KIT

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included
Y Sites Probabilities

Log-Odds: Y Sites / Y Background

Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown

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substrate_uniprot site source substrate_genes site_seq
A5A3E0 Y1062 Sugiyama POTEF A26C1B GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______
A5A3E0 Y791 Sugiyama POTEF A26C1B MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPVLLTEATLN
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A5YKK6 Y851 Sugiyama CNOT1 CDC39 KIAA1007 NOT1 AD-005 QVWPEANQHFSKEIDDEANSyFQRIYNHPPHPTMSVDEVLE
A6NMY6 Y147 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B sLIEIICsRtNQELQEINRVyKEMYKtDLEKDIIsDtsGDF
O00116 Y645 Sugiyama AGPS AAG5 QWLKESIsDVGFGMLKSVKEyVDPNNIFGNRNLL_______
O00170 Y202 Sugiyama AIP XAP2 IHQEGNRLYREGHVKEAAAKyyDAIACLKNLQMKEQPGSPE
O00170 Y203 Sugiyama AIP XAP2 HQEGNRLYREGHVKEAAAKyyDAIACLKNLQMKEQPGSPEW
O00193 Y84 Sugiyama SMAP C11orf58 TSHFRTGEEDKKINEELEsQyQQsMDsKLSGRYRRHCGLGF
O00401 Y256 Sugiyama WASL FDMCGIsEAQLKDRETSKVIyDFIEKTGGVEAVKNELRRQA
O00429 Y101 Sugiyama DNM1L DLP1 DRP1 EENGVEAEEWGKFLHTKNKLyTDFDEIRQEIENETERISGN
O00469 Y444 Sugiyama PLOD2 LWSNFWGALSPDGYYARsEDyVDIVQGNRVGVWNVPYMANV
O14639 Y383 Sugiyama ABLIM1 ABLIM KIAA0059 LIMAB1 sIPGsPGHtIyAKVDNEILDyKDLAAIPKVKAIYDIERPDL
O14818 T147 Sugiyama PSMA7 HSPC FGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKS
O14818 T152 Sugiyama PSMA7 HSPC LIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFL
O14818 Y153 Sugiyama PSMA7 HSPC IVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFLE
O14818 Y176 Sugiyama PSMA7 HSPC WKANAIGRGAKSVREFLEKNyTDEAIETDDLTIKLVIKALL
O14950 Y143 Sugiyama MYL12B MRLC2 MYLC2B LRELLttMGDRFtDEEVDELyREAPIDKKGNFNyIEFtRIL
O14950 Y156 Sugiyama MYL12B MRLC2 MYLC2B DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
O14974 Y911 Sugiyama PPP1R12A MBS MYPT1 ETssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDSTD
O14979 Y167 Sugiyama HNRNPDL HNRPDL JKTBP DGKMFIGGLSWDTsKKDLtEyLSRFGEVVDCtIKTDPVTGR
O15067 Y538 Sugiyama PFAS KIAA0361 GAGGNGNVLKELsDPAGAIIytsRFQLGDPTLNALEIWGAE
O15230 Y81 Sugiyama LAMA5 KIAA0533 KIAA1907 SATCGEEAPARGSPRPTEDLyCKLVGGPVAGGDPNQTIRGQ
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O15371 Y50 Sugiyama EIF3D EIF3S7 yQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQYA
O43390 Y376 Sugiyama HNRNPR HNRPR ILEKSFSEFGKLERVKKLKDyAFVHFEDRGAAVKAMDEMNG
O43390 Y435 Sugiyama HNRNPR HNRPR KRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGGR
O43390 Y436 Sugiyama HNRNPR HNRPR RKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGGRG
O43615 T198 Sugiyama TIMM44 MIMT44 TIM44 ALsQGVEsVKKEIDDsVLGQtGPyRRPQRLRKRTEFAGDKF
O43707 Y234 Sugiyama ACTN4 KLRKDDPVTNLNNAFEVAEKyLDIPKMLDAEDIVNtARPDE
O43707 Y878 Sugiyama ACTN4 DKNFITAEELRRELPPDQAEyCIARMAPyQGPDAVPGALDy
O43852 Y106 Sugiyama CALU GFVtVDELKDWIKFAQKRWIyEDVERQWKGHDLNEDGLVsW
O43852 Y185 Sugiyama CALU KDGDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNAD
O43852 Y187 Sugiyama CALU GDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNADGF
O43852 Y213 Sugiyama CALU VQEtMEDIDKNADGFIDLEEyIGDMysHDGNtDEPEWVKTE
O43852 Y263 Sugiyama CALU KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
O43852 Y47 Sugiyama CALU RVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQLtPE
O43865 Y28 Sugiyama AHCYL1 DCAL IRBIT XPVKONA PLPGVGEELKQAKEIEDAEKysFMATVTKAPKKQIQFADDM
O60341 Y135 Sugiyama KDM1A AOF2 KDM1 KIAA0601 LSD1 RAKVEyREMDEsLANLsEDEyysEEERNAKAEKEKKLPPPP
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60664 Y235 Sugiyama PLIN3 M6PRBP1 TIP47 AtsLDGFDVAsVQQQRQEQSyFVRLGsLSERLRQHAyEHsL
O60664 Y95 Sugiyama PLIN3 M6PRBP1 TIP47 VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE
O60716 Y228 Sugiyama CTNND1 KIAA0384 yPPDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGy
O60739 Y30 Sugiyama EIF1B FDPFADATKGDDLLPAGTEDyIHIRIQQRNGRKtLttVQGI
O60763 Y655 Sugiyama USO1 VDP DKKEEEVKKTLEQHDNIVTHyKNMIREQDLQLEELRQQVST
O60814 Y41 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
O60814 Y43 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
O75223 Y156 Sugiyama GGCT C7orf24 CRF21 sPQYKKIICMGAKENGLPLEyQEKLKAIEPNDytGKVsEEI
O75347 Y75 Sugiyama TBCA EILQEsRMMIPDCQRRLEAAyLDLQRILENEKDLEEAEEyK
O75347 Y94 Sugiyama TBCA AyLDLQRILENEKDLEEAEEyKEARLVLDsVKLEA______
O75348 Y47 Sugiyama ATP6V1G1 ATP6G ATP6G1 ATP6J KRKNRRLKQAKEEAQAEIEQyRLQREKEFKAKEAAALGsRG
O75391 Y163 Sugiyama SPAG7 QRQEEEAAQQGPVVVsPAsDyKDKYSHLIGKGAAKDAAHML
O75874 Y391 Sugiyama IDH1 PICD FMTKDLAACIKGLPNVQRsDyLNTFEFMDKLGENLKIKLAQ
O94906 Y105 Sugiyama PRPF6 C20orf14 AGSLFSSGPYEKDDEEADAIyAALDKRMDERRKERREQREK
O94919 T132 Sugiyama ENDOD1 KIAA0830 INEAEAITSVNSLGSKQALNtDyLDsDyQRGQLYPFSLSSD
O95218 Y114 Sugiyama ZRANB2 ZIS ZNF265 AKLEERtGYGGGFNERENVEyIEREEsDGEyDEFGRKKKKY
O95218 Y167 Sugiyama ZRANB2 ZIS ZNF265 EVEDKEsEGEEEDEDEDLsKyKLDEDEDEDDADLsKyNLDA
O95297 Y263 Sugiyama MPZL1 PZR UNQ849/PRO1787 QLDHsGGHHSDKINKSEsVVyADIRKN______________
O95347 Y938 Sugiyama SMC2 CAPE SMC2L1 PRO0324 SKHKREAEDGAAKVSKMLKDyDWINAERHLFGQPNSAYDFK
O95433 Y323 Sugiyama AHSA1 C14orf3 HSPC322 EGRGIPAPEEERTRQGWQRyyFEGIKQTFGYGARLF_____
O95817 Y240 Sugiyama BAG3 BIS AAQPsFHQAQKTHyPAQQGEyQtHQPVyHKIQGDDWEPRPL
O95881 Y137 Sugiyama TXNDC12 TLP19 UNQ713/PRO1376 FLDPSGKVHPEIINENGNPsyKyFyVsAEQVVQGMKEAQER
O96019 Y69 Sugiyama ACTL6A BAF53 BAF53A INO80K DGsTLMEIDGDKGKQGGPtyyIDtNALRVPRENMEAIsPLK
P00338 Y239 Sugiyama LDHA PIG19 GtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVADL
P00505 Y96 Sugiyama GOT2 KYAT4 VLPSVRKAEAQIAAKNLDKEyLPIGGLAEFCKASAELALGE
P00533 Y1197 Sugiyama EGFR ERBB ERBB1 HER1 FPKEAKPNGIFKGstAENAEyLRVAPQsSEFIGA_______
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P00558 Y196 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MVGVNLPQKAGGFLMKKELNyFAKALEsPERPFLAILGGAK
P02545 Y45 Sugiyama LMNA LMN1 RItRLQEKEDLQELNDRLAVyIDRVRsLETENAGLRLRItE
P02786 Y152 Sugiyama TFRC sEKLDstDFTGtIKLLNENsyVPREAGsQKDENLALyVENQ
P02786 Y168 Sugiyama TFRC NENsyVPREAGsQKDENLALyVENQFREFKLSKVWRDQHFV
P02786 Y402 Sugiyama TFRC KEIKILNIFGVIKGFVEPDHyVVVGAQRDAWGPGAAKSGVG
P04080 T51 Sugiyama CSTB CST6 STFB ENKKFPVFKAVSFKSQVVAGtNyFIKVHVGDEDFVHLRVFQ
P04080 Y97 Sugiyama CSTB CST6 STFB NKPLtLsNyQTNKAKHDELtyF___________________
P04083 Y21 Sugiyama ANXA1 ANX1 LPC1 MAMVsEFLKQAWFIENEEQEyVQtVKssKGGPGsAVsPyPt
P04181 Y50 Sugiyama OAT TKKtVQGPPtSDDIFEREyKyGAHNyHPLPVALERGKGIyL
P04181 Y55 Sugiyama OAT QGPPtSDDIFEREyKyGAHNyHPLPVALERGKGIyLWDVEG
P04406 Y314 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK
P04406 Y320 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04920 Y73 Sugiyama SLC4A2 AE2 EPB3L1 HKB3 MPB3L EAGsRGGEEPGRsYGEEDFEyHRQSSHHIHHPLSTHLPPDA
P05067 Y308 Sugiyama APP A4 AD1 REVCSEQAETGPCRAMISRWyFDVTEGKCAPFFyGGCGGNR
P05362 Y455 Sugiyama ICAM1 GtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTRKVTVNVL
P05787 Y204 Sugiyama KRT8 CYK8 NKRTEMENEFVLIKKDVDEAyMNKVELESRLEGLTDEINFL
P05787 Y282 Sugiyama KRT8 CYK8 EVKAQyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDLRR
P06730 Y34 Sugiyama EIF4E EIF4EL1 EIF4F PPttEEEKtEsNQEVANPEHyIKHPLQNRWALWFFKNDKsK
P06733 S268 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 ASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyP
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 Y131 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 ILGVsLAVCKAGAVEKGVPLyRHIADLAGNsEVILPVPAFN
P06733 Y189 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 MILPVGAANFREAMRIGAEVyHNLKNVIKEKyGKDAtNVGD
P06733 Y270 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV
P06733 Y280 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD
P06733 Y287 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 PsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKF
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06899 Y41 Sugiyama H2BC11 H2BFR HIST1H2BJ KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMG
P06899 Y43 Sugiyama H2BC11 H2BFR HIST1H2BJ QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMGIM
P07195 Y240 Sugiyama LDHB GTDNDSENWKEVHKMVVEsAyEVIKLKGYTNWAIGLSVADL
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07355 Y147 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sLIEIICsRtNQELQEINRVyKEMYKtDLEKDIIsDtsGDF
P07355 Y188 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 Y106 Sugiyama TUBB TUBB5 OK/SW-cl.56 RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAES
P07437 Y50 Sugiyama TUBB TUBB5 OK/SW-cl.56 IDPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEP
P07437 Y51 Sugiyama TUBB TUBB5 OK/SW-cl.56 DPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPG
P07437 Y59 Sugiyama TUBB TUBB5 OK/SW-cl.56 DsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDsVRsG
P07686 Y463 Sugiyama HEXB HCC7 VILSAPWYLDLISYGQDWRKyyKVEPLDFGGtQKQKQLFIG
P07686 Y464 Sugiyama HEXB HCC7 ILSAPWYLDLISYGQDWRKyyKVEPLDFGGtQKQKQLFIGG
P07711 Y311 Sugiyama CTSL CTSL1 DNNKYWLVKNsWGEEWGMGGyVKMAKDRRNHCGIAsAAsyP
P07814 Y1504 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KPLCELQPGAKCVCGKNPAKyytLFGRsy____________
P07814 Y1505 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PLCELQPGAKCVCGKNPAKyytLFGRsy_____________
P07814 Y827 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK
P07858 Y244 Sugiyama CTSB CPSB HYGYNSYSVSNSEKDIMAEIyKNGPVEGAFSVYSDFLLYKS
P07900 Y197 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA GEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIGyP
P07900 Y284 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI
P07900 Y309 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF
P07900 Y313 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG
P07900 Y434 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KNLVKKCLELFtELAEDKENyKKFyEQFSKNIKLGIHEDsQ
P07900 Y492 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLR
P07900 Y493 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLRK
P07900 Y61 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KEIFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLI
P08238 Y192 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIGyP
P08238 Y276 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI
P08238 Y301 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF
P08238 Y305 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG
P08238 Y430 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KKCLELFsELAEDKENyKKFyEAFSKNLKLGIHEDstNRRR
P08238 Y472 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKE
P08238 Y484 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR
P08238 Y56 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEIFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDII
P08238 Y619 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR
P08670 Y291 Sugiyama VIM DVRQQyEsVAAKNLQEAEEWyKSKFADLsEAANRNNDALRQ
P08708 Y84 Sugiyama RPS17 RPS17L GPVRGISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKE
P08758 Y94 Sugiyama ANXA5 ANX5 ENX2 PP4 TGKFEKLIVALMKPSRLyDAyELKHALKGAGTNEKVLtEII
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09234 Y12 Sugiyama SNRPC _________MPKFyCDyCDtyLtHDsPsVRKTHCSGRKHKE
P09651 Y341 Sugiyama HNRNPA1 HNRPA1 QSSNFGPMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGss
P09651 Y347 Sugiyama HNRNPA1 HNRPA1 PMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGssssssyG
P09874 Y794 Sugiyama PARP1 ADPRT PPOL AySLLRGGsDDssKDPIDVNyEKLKTDIKVVDRDSEEAEII
P0CG38 Y1062 Sugiyama POTEI GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG38 Y791 Sugiyama POTEI MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAPLN
P0CG39 Y1025 Sugiyama POTEJ GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG39 Y754 Sugiyama POTEJ MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAPLN
P10398 Y155 Sugiyama ARAF ARAF1 PKS PKS2 HCSSKVPTVCVDMSTNRQQFyHsVQDLsGGsRQHEAPsNRP
P10721 S715 Sugiyama KIT SCFR EDHAEAALyKNLLHSKESSCsDsTNEyMDMKPGVsyVVPTK
P10721 S717 Sugiyama KIT SCFR HAEAALyKNLLHSKESSCsDsTNEyMDMKPGVsyVVPTKAD
P10721 S729 Sugiyama KIT SCFR SKESSCsDsTNEyMDMKPGVsyVVPTKADKRRsVRIGsyIE
P10721 S821 Sugiyama KIT SCFR THGRITKICDFGLARDIKNDsNyVVKGNARLPVKWMAPESI
P10721 S937 Sugiyama KIT SCFR FKQIVQLIEKQISEstNHIysNLANCsPNRQKPVVDHSVRI
P10721 S943 Sugiyama KIT SCFR LIEKQISEstNHIysNLANCsPNRQKPVVDHSVRINsVGst
P10721 S959 Sugiyama KIT SCFR LANCsPNRQKPVVDHSVRINsVGstAsSSQPLLVHDDV___
P10721 S962 Sugiyama KIT SCFR CsPNRQKPVVDHSVRINsVGstAsSSQPLLVHDDV______
P10721 T607 Sugiyama KIT SCFR NRLSFGKTLGAGAFGKVVEAtAyGLIKSDAAMTVAVKMLKP
P10721 T932 Sugiyama KIT SCFR LKRPTFKQIVQLIEKQISEstNHIysNLANCsPNRQKPVVD
P10721 Y547 EPSD|PSP|Sugiyama KIT SCFR IGFVIVAGMMCIIVMILTYKyLQKPMyEVQWKVVEEINGNN
P10721 Y553 EPSD|PSP|Sugiyama KIT SCFR AGMMCIIVMILTYKyLQKPMyEVQWKVVEEINGNNyVyIDP
P10721 Y568 SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama KIT SCFR LQKPMyEVQWKVVEEINGNNyVyIDPTQLPYDHKWEFPRNR
P10721 Y570 SIGNOR|ELM|iPTMNet|EPSD|PSP KIT SCFR KPMyEVQWKVVEEINGNNyVyIDPTQLPYDHKWEFPRNRLS
P10721 Y609 Sugiyama KIT SCFR LSFGKTLGAGAFGKVVEAtAyGLIKSDAAMTVAVKMLKPSA
P10721 Y703 SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama KIT SCFR RRKRDSFICSKQEDHAEAALyKNLLHSKESSCsDsTNEyMD
P10721 Y721 EPSD|PSP|Sugiyama KIT SCFR ALyKNLLHSKESSCsDsTNEyMDMKPGVsyVVPTKADKRRs
P10721 Y730 Sugiyama KIT SCFR KESSCsDsTNEyMDMKPGVsyVVPTKADKRRsVRIGsyIER
P10721 Y747 Sugiyama KIT SCFR GVsyVVPTKADKRRsVRIGsyIERDVTPAIMEDDELALDLE
P10721 Y823 SIGNOR|EPSD|PSP|Sugiyama KIT SCFR GRITKICDFGLARDIKNDsNyVVKGNARLPVKWMAPESIFN
P10721 Y900 EPSD|Sugiyama KIT SCFR YKMIKEGFRMLsPEHAPAEMyDIMKTCWDADPLKRPTFKQI
P10721 Y936 SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama KIT SCFR TFKQIVQLIEKQISEstNHIysNLANCsPNRQKPVVDHSVR
P10809 Y223 Sugiyama HSPD1 HSP60 DGKtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAy
P10809 Y243 Sugiyama HSPD1 HSP60 yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI
P11047 Y352 Sugiyama LAMC1 LAMB2 tAEsASECLPCDCNGRsQECyFDPELyRSTGHGGHCTNCQD
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11142 Y545 Sugiyama HSPA8 HSC70 HSP73 HSPA10 YKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKINDE
P11233 Y153 Sugiyama RALA RAL DKRQVsVEEAKNRAEQWNVNyVETSAKTRANVDKVFFDLMR
P11413 Y118 Sugiyama G6PD LEDFFARNsyVAGQyDDAAsyQRLNsHMNALHLGsQANRLF
P11940 Y194 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF
P12004 Y249 Sugiyama PCNA MSADVPLVVEYKIADMGHLKyyLAPKIEDEEGs________
P12004 Y250 Sugiyama PCNA SADVPLVVEYKIADMGHLKyyLAPKIEDEEGs_________
P12277 Y125 Sugiyama CKB CKBB EHKTDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPH
P12277 Y39 Sugiyama CKB CKBB EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT
P12814 Y215 Sugiyama ACTN1 KLRKDDPLTNLNTAFDVAEKyLDIPKMLDAEDIVGtARPDE
P12814 Y842 Sugiyama ACTN1 DTDTADQVMASFKILAGDKNyITMDELRRELPPDQAEyCIA
P12814 Y859 Sugiyama ACTN1 DKNyITMDELRRELPPDQAEyCIARMAPYTGPDSVPGALDY
P12956 Y30 Sugiyama XRCC6 G22P1 tEGDEEAEEEQEENLEAsGDyKYsGRDsLIFLVDASKAMFE
P13073 Y38 Sugiyama COX4I1 COX4 SVCVRAHESVVKsEDFsLPAyMDRRDHPLPEVAHVKHLSAS
P13639 Y443 Sugiyama EEF2 EF2 TGLKVRIMGPNytPGKKEDLyLKPIQRTILMMGRYVEPIED
P13639 Y671 Sugiyama EEF2 EF2 CFGPDGTGPNILTDITKGVQyLNEIKDSVVAGFQWATKEGA
P13639 Y730 Sugiyama EEF2 EF2 HADAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQ
P13667 Y448 Sugiyama PDIA4 ERP70 ERP72 RAATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLs
P13667 Y458 Sugiyama PDIA4 ERP70 ERP72 VLEVAKDFPEytFAIADEEDyAGEVKDLGLsEsGEDVNAAI
P13667 Y565 Sugiyama PDIA4 ERP70 ERP72 DVLIEFYAPWCGHCKQLEPVyNsLAKKYKGQKGLVIAKMDA
P13674 Y282 Sugiyama P4HA1 P4HA ASDDQSDQKTTPKKKGVAVDyLPERQKyEMLCRGEGIKMTP
P13693 Y18 Sugiyama TPT1 ___MIIYRDLIsHDEMFsDIyKIREIADGLCLEVEGKMVSR
P13798 Y17 Sugiyama APEH D3F15S2 D3S48E DNF15S2 ____MERQVLLsEPEEAAALyRGLSRQPALsAACLGPEVtT
P13929 Y131 Sugiyama ENO3 ILGVSLAVCKAGAAEKGVPLyRHIADLAGNPDLILPVPAFN
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P13987 Y86 Sugiyama CD59 MIC11 MIN1 MIN2 MIN3 MSK21 KFEHCNFNDVtTRLRENELtyyCCKKDLCNFNEQLENGGTS
P13987 Y87 Sugiyama CD59 MIC11 MIN1 MIN2 MIN3 MSK21 FEHCNFNDVtTRLRENELtyyCCKKDLCNFNEQLENGGTSL
P14625 Y401 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 VTFKSILFVPTSAPRGLFDEyGsKKSDYIKLYVRRVFITDD
P14625 Y429 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IKLYVRRVFITDDFHDMMPKyLNFVKGVVDsDDLPLNVsRE
P14625 Y527 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 AKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAGsSRK
P14625 Y539 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDItsLDQyVERMKEKQDKIyFMAGsSRKEAEssPFVERLL
P14625 Y677 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 NMERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIRDM
P14649 Y86 Sugiyama MYL6B MLC1SA LEEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVL
P14854 Y57 Sugiyama COX6B1 COX6B FHRCQKAMTAKGGDIsVCEWyQRVYQsLCPtsWVTDWDEQR
P14927 Y90 Sugiyama UQCRB UQBP NLKHQILPKEQWTKyEEENFyLEPyLKEVIRERKEREEWAK
P15259 Y92 Sugiyama PGAM2 PGAMM DGTDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQV
P15311 Y424 Sugiyama EZR VIL2 ERQAVDQIKsQEQLAAELAEytAKIALLEEARRRKEDEVEE
P15328 Y80 Sugiyama FOLR1 FOLR WRKNACCSTNTSQEAHKDVsyLyRFNWNHCGEMAPACKRHF
P15880 Y248 Sugiyama RPS2 RPS4 GCtAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQE
P15880 Y250 Sugiyama RPS2 RPS4 tAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQEFt
P17066 Y43 Sugiyama HSPA6 HSP70B' FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P17676 Y139 Sugiyama CEBPB TCF5 PP9092 SDLFSDDYGGKNCKKPAEyGyVsLGRLGAAKGALHPGCFAP
P17812 Y473 Sugiyama CTPS1 CTPS RRtLFQTKNsVMRKLyGDADyLEERHRHRFEVNPVWKKCLE
P17844 Y59 Sugiyama DDX5 G17P1 HELR HLR1 EKLVKKKWNLDELPKFEKNFyQEHPDLARRtAQEVETYRRS
P17980 Y185 Sugiyama PSMC3 TBP1 PtEyDsRVKAMEVDERPtEQysDIGGLDKQIQELVEAIVLP
P17980 Y381 Sugiyama PSMC3 TBP1 ARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQCKAVCV
P17987 Y545 Sugiyama TCP1 CCT1 CCTA LRIDDLIKLHPESKDDKHGsyEDAVHsGALND_________
P18084 Y509 Sugiyama ITGB5 CSPGYLGTRCECQDGENQsVyQNLCREAEGKPLCSGRGDCS
P18206 Y822 Sugiyama VCL KAVAGNIsDPGLQKsFLDsGyRILGAVAKVREAFQPQEPDF
P18615 Y133 Sugiyama NELFE RD RDBP sIsADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEA
P18615 Y170 Sugiyama NELFE RD RDBP GEEAEGPGAGDGPPRsFDWGyEERSGAHSsAsPPRsRSRDR
P18615 Y372 Sugiyama NELFE RD RDBP NsPKGCHRDKRTQIVysDDVyKENLVDGF____________
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18669 S137 Sugiyama PGAM1 PGAMA CDABP0006 RsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLK
P18669 Y142 Sugiyama PGAM1 PGAMA CDABP0006 PPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIAR
P18669 Y92 Sugiyama PGAM1 PGAMA CDABP0006 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
P19105 Y142 Sugiyama MYL12A MLCB MRLC3 RLC LRELLttMGDRFtDEEVDELyREAPIDKKGNFNyIEFtRIL
P19105 Y155 Sugiyama MYL12A MLCB MRLC3 RLC DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
P19338 Y433 Sugiyama NCL FEDAAEIRLVSKDGKSKGIAyIEFKTEADAEKTFEEKQGtE
P19338 Y462 Sugiyama NCL AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs
P20042 Y176 Sugiyama EIF2S2 EIF2B GIsFsNQtGPAWAGSERDytyEELLNRVFNIMREKNPDMVA
P20618 S151 Sugiyama PSMB1 PSC5 PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA
P20618 Y150 Sugiyama PSMB1 PSC5 FPYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSAS
P20618 Y158 Sugiyama PSMB1 PSC5 IGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLD
P20810 Y618 Sugiyama CAST KAKAEHRDKLGERDDTIPPEyRHLLDDNGQDKPVKPPTKKS
P21980 Y369 Sugiyama TGM2 PGYEGWQALDPTPQEKsEGtyCCGPVPVRAIKEGDLstKyD
P22234 Y22 Sugiyama PAICS ADE2 AIRC PAIS AtAEVLNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAG
P22314 Y55 Sugiyama UBA1 A1S9T UBE1 SVPTNGMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSV
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P23193 Y126 Sugiyama TCEA1 GTF2S TFIIS EsTSsGNVsNRKDETNARDTyVsSFPRAPstsDsVRLKCRE
P23246 Y488 Sugiyama SFPQ PSF PMYQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQV
P23246 Y490 Sugiyama SFPQ PSF YQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQVEK
P23284 Y119 Sugiyama PPIB CYPB DFMIQGGDFtRGDGtGGKsIyGERFPDENFKLKHyGPGWVs
P23434 Y139 Sugiyama GCSH EVTEINEALAENPGLVNKSCyEDGWLIKMtLsNPsELDELM
P23434 Y164 Sugiyama GCSH LIKMtLsNPsELDELMsEEAyEKYIKSIEE___________
P23526 Y165 Sugiyama AHCY SAHH QLLPGIRGIsEEtTTGVHNLyKMMANGILKVPAINVNDsVt
P23527 Y41 Sugiyama H2BC17 H2BFH H2BFN HIST1H2BO KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMG
P23527 Y43 Sugiyama H2BC17 H2BFH H2BFN HIST1H2BO QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMGIM
P23528 T91 Sugiyama CFL1 CFL FVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPESAPL
P23528 Y140 Sugiyama CFL1 CFL SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs
P23528 Y68 Sugiyama CFL1 CFL ILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAt
P23528 Y82 Sugiyama CFL1 CFL QtVDDPyAtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFI
P23528 Y89 Sugiyama CFL1 CFL AtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPESA
P23588 Y211 Sugiyama EIF4B DsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDRYDsD
P24534 Y18 Sugiyama EEF1B2 EEF1B EF1B ___MGFGDLKsPAGLQVLNDyLADKSYIEGYVPsQADVAVF
P24752 Y214 Sugiyama ACAT1 ACAT MAT GsCAENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNE
P24844 Y156 Sugiyama MYL9 MLC2 MRLC1 MYRL2 DEEVDEMyREAPIDKKGNFNyVEFTRILKHGAKDKDD____
P25205 Y19 Sugiyama MCM3 __MAGtVVLDDVELREAQRDyLDFLDDEEDQGIyQsKVREL
P25205 Y32 Sugiyama MCM3 LREAQRDyLDFLDDEEDQGIyQsKVRELIsDNQyRLIVNVN
P25205 Y45 Sugiyama MCM3 DEEDQGIyQsKVRELIsDNQyRLIVNVNDLRRKNEKRANRL
P25208 Y58 Sugiyama NFYB HAP3 SMNDHEDTNGSKESFREQDIyLPIANVARIMKNAIPQTGKI
P25398 Y127 Sugiyama RPS12 sCVVVKDYGKESQAKDVIEEyFKCKK_______________
P26196 Y469 Sugiyama DDX6 HLR2 RCK IEEQLGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP______
P26196 Y473 Sugiyama DDX6 HLR2 RCK LGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP__________
P26599 Y127 Sugiyama PTBP1 PTB ANTMVNYYTSVTPVLRGQPIyIQFsNHKELKtDSSPNQARA
P27348 Y149 Sugiyama YWHAQ LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG
P27348 Y48 Sugiyama YWHAQ AVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSIEQK
P27540 Y561 Sugiyama ARNT BHLHE2 PLEKSDGLFAQDRDPRFsEIyHNINADQSKGISSSTVPATQ
P27695 Y128 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 LQELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGD
P27695 Y45 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 KSKTAAKKNDKEAAGEGPALyEDPPDQKtsPsGKPAtLKIC
P27797 Y109 Sugiyama CALR CRTC QTLVVQFTVKHEQNIDCGGGyVKLFPNSLDQTDMHGDSEYN
P27816 Y47 Sugiyama MAP4 AtLEAEAFDDVVGETVGKTDyIPLLDVDEKtGNsESKKKPC
P27824 Y70 Sugiyama CANX TAPPSSPKVTYKAPVPtGEVyFADsFDRGTLSGWILSKAKK
P28066 Y185 Sugiyama PSMA5 CDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSLIILKQV
P29353 Y427 Sugiyama SHC1 SHC SHCA RKQMPPPPPCPGRELFDDPsyVNVQNLDKARQAVGGAGPPN
P29401 Y202 Sugiyama TKT LDINRLGQsDPAPLQHQMDIyQKRCEAFGWHAIIVDGHSVE
P29401 Y481 Sugiyama TKT AANTKGICFIRTsRPENAIIyNNNEDFQVGQAKVVLKSKDD
P29692 Y26 Sugiyama EEF1D EF1D LAHEKIWFDKFKYDDAERRFyEQMNGPVAGAsRQENGAsVI
P30043 S202 Sugiyama BLVRB FLR SCAN GHFMLRCLttDEyDGHstyPsHQyQ________________
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P30086 Y176 Sugiyama PEBP1 PBP PEBP KKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK_________
P30086 Y64 Sugiyama PEBP1 PBP PEBP tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW
P30101 Y100 Sugiyama PDIA3 ERP57 ERP60 GRP58 LAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRt
P30101 Y115 Sugiyama PDIA3 ERP57 ERP60 GRP58 yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA
P30101 Y356 Sugiyama PDIA3 ERP57 ERP60 GRP58 FVMQEEFsRDGKALERFLQDyFDGNLKRyLKsEPIPESNDG
P30101 Y67 Sugiyama PDIA3 ERP57 ERP60 GRP58 LMLVEFFAPWCGHCKRLAPEyEAAAtRLKGIVPLAKVDCTA
P30622 Y108 Sugiyama CLIP1 CYLN1 RSN AGIVLDEPIGKNDGSVAGVRyFQCEPLKGIFTRPSKLTRKV
P31153 Y242 Sugiyama MAT2A AMS2 MATA2 LKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLt
P31327 Y1450 Sugiyama CPS1 GsIDLVINLPNNNTKFVHDNyVIRRTAVDSGIPLLTNFQVT
P31943 Y266 Sugiyama HNRNPH1 HNRPH HNRPH1 yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst
P31946 Y151 Sugiyama YWHAB LsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLG
P31946 Y213 Sugiyama YWHAB LAKTAFDEAIAELDtLNEEsyKDstLIMQLLRDNLtLWtSE
P31946 Y50 Sugiyama YWHAB AVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P31947 Y151 Sugiyama SFN HME1 LAEVATGDDKKRIIDSARsAyQEAMDISKKEMPPTNPIRLG
P31947 Y19 Sugiyama SFN HME1 __MERASLIQKAKLAEQAERyEDMAAFMKGAVEKGEELsCE
P31947 Y213 Sugiyama SFN HME1 LAKTtFDEAMADLHtLsEDsyKDstLIMQLLRDNLtLWTAD
P31947 Y48 Sugiyama SFN HME1 GAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsIEQK
P31948 Y354 Sugiyama STIP1 DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG
P31948 Y41 Sugiyama STIP1 DDALQCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDG
P32004 Y310 Sugiyama L1CAM CAML1 MIC5 YQNHNKTLQLLKVGEEDDGEyRCLAENSLGSARHAYYVTVE
P32119 Y115 Sugiyama PRDX2 NKEFB TDPX1 GLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFIIDGK
P32929 S61 Sugiyama CTH ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA
P32969 Y180 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 LIQQATTVKNKDIRKFLDGIyVsEKGtVQQADE________
P33316 Y167 Sugiyama DUT PPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDVGAG
P33778 Y41 Sugiyama H2BC3 H2BFF HIST1H2BB KAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKAMG
P33778 Y43 Sugiyama H2BC3 H2BFF HIST1H2BB QKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKAMGIM
P33993 Y102 Sugiyama MCM7 CDC47 MCM2 QELLPQYKEREVVNKDVLDVyIEHRLMMEQRSRDPGMVRsP
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P34932 Y30 Sugiyama HSPA4 APG2 HSPH2 FQSCYVAVARAGGIETIANEysDRCtPACIsFGPKNRSIGA
P34932 Y597 Sugiyama HSPA4 APG2 HSPH2 VDLPIENQLLWQIDREMLNLyIENEGKMIMQDKLEKERNDA
P35232 Y259 PSP PHB1 PHB RKLEAAEDIAyQLSRSRNItyLPAGQSVLLQLPQ_______
P35606 Y824 Sugiyama COPB2 AFVVEEWVKETHADLWPAKQyPLVtPNEERNVMEEGKDFQP
P36871 Y476 Sugiyama PGM1 GKQFSANDKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTD
P36954 Y54 Sugiyama POLR2I ILLyACRNCDYQQEADNSCIyVNKITHEVDELtQIIADVsQ
P37108 T29 Sugiyama SRP14 FLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGtVEGF
P37802 Y192 Sugiyama TAGLN2 KIAA0120 CDABP0035 NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P38646 Y196 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 EtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNV
P38919 Y54 Sugiyama EIF4A3 DDX48 KIAA0111 VDVTPTFDTMGLREDLLRGIyAyGFEKPsAIQQRAIKQIIK
P38919 Y56 Sugiyama EIF4A3 DDX48 KIAA0111 VTPTFDTMGLREDLLRGIyAyGFEKPsAIQQRAIKQIIKGR
P39019 Y48 Sugiyama RPS19 LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39687 Y131 Sugiyama ANP32A C15orf1 LANP MAPM PHAP1 KLENLKsLDLFNCEVtNLNDyRENVFKLLPQLtyLDGyDRD
P40763 Y176 Sugiyama STAT3 APRF QDLEQKMKVVENLQDDFDFNyKTLKsQGDMQDLNGNNQsVT
P41219 Y287 Sugiyama PRPH NEF4 PRPH1 DIRAQYESIAAKNLQEAEEWyKSKYADLSDAANRNHEALRQ
P41567 Y30 Sugiyama EIF1 SUI1 FDPFADAsKGDDLLPAGTEDyIHIRIQQRNGRKtLttVQGI
P42025 Y33 Sugiyama ACTR1B CTRN2 VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALE
P42025 Y38 Sugiyama ACTR1B CTRN2 SGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALEGDLFI
P42224 Y170 Sugiyama STAT1 KDKVMCIEHEIKsLEDLQDEyDFKCKTLQNREHETNGVAKS
P42224 Y701 SIGNOR|EPSD STAT1 YSRPKEAPEPMELDGPKGtGyIKtELIsVsEVHPSRLQttD
P43121 Y222 Sugiyama MCAM MUC18 YTLQSILKAQLVKEDKDAQFyCELNYRLPSGNHMKEsREVT
P43243 Y214 Sugiyama MATR3 KIAA0723 PsLNPVLDyDHGsRsQEsGyyDRMDyEDDRLRDGERCRDDs
P43243 Y243 Sugiyama MATR3 KIAA0723 RLRDGERCRDDsFFGEtsHNyHKFDsEyERMGRGPGPLQER
P43490 Y34 Sugiyama NAMPT PBEF PBEF1 ATDSYKVTHYKQYPPNTSKVysyFECREKKTENSKLRKVKY
P45974 Y849 Sugiyama USP5 ISOT WVIYNDQKVCASEKPPKDLGyIyFyQRVAS___________
P46776 Y52 Sugiyama RPL27A RGNAGGLHHHRINFDKyHPGyFGKVGMKHYHLKRNQsFCPt
P46777 Y219 Sugiyama RPL5 MSTP030 IMGQNVADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEM
P46777 Y240 Sugiyama RPL5 MSTP030 KKQFsQyIKNsVtPDMMEEMyKKAHAAIRENPVyEKKPKKE
P46778 Y30 Sugiyama RPL21 GTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQK
P46937 Y407 Sugiyama YAP1 YAP65 NsGtyHsRDEstDsGLsMssysVPRtPDDFLNsVDEMDTGD
P47224 Y114 Sugiyama RABIF MSS4 RASGRF3 CADCEIGPIGWHCLDDKNSFyVALERVSHE___________
P47712 Y535 Sugiyama PLA2G4A CPLA2 PLA2G4 sFDDDELDAAVADPDEFERIyEPLDVKSKKIHVVDSGLTFN
P47756 Y232 Sugiyama CAPZB NIGRLVEDMENKIRstLNEIyFGKTKDIVNGLRSVQTFADK
P47756 Y59 Sugiyama CAPZB LLSSVDQPLKIARDKVVGKDyLLCDyNRDGDSyRsPWSNKy
P47914 Y98 Sugiyama RPL29 PKEVKPKIPKGVSRKLDRLAyIAHPKLGKRARARIAKGLRL
P48643 Y274 Sugiyama CCT5 CCTE KIAA0098 PFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQQIKE
P48741 Y43 Sugiyama HSPA7 HSP70B FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P49023 Y409 Sugiyama PXN EEIGSRNFFERDGQPYCEKDyHNLFsPRCYYCNGPILDKVV
P49207 Y32 Sugiyama RPL34 sYNtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGR
P49327 Y2462 Sugiyama FASN FAS NVMLLRAKtGGAyGEDLGADyNLsQVCDGKVsVHVIEGDHR
P49327 Y277 Sugiyama FASN FAS KEQGVtFPsGDIQEQLIRSLyQsAGVAPEsFEyIEAHGtGT
P49327 Y289 Sugiyama FASN FAS QEQLIRSLyQsAGVAPEsFEyIEAHGtGTKVGDPQELNGIt
P49327 Y45 Sugiyama FASN FAS NLIGGVDMVTDDDRRWKAGLyGLPRRsGKLKDLSRFDAsFF
P49588 Y192 Sugiyama AARS1 AARS KDNFWEMGDtGPCGPCsEIHyDRIGGRDAAHLVNQDDPNVL
P49588 Y295 Sugiyama AARS1 AARS GARPYTGKVGAEDADGIDMAyRVLADHARTITVALADGGRP
P49591 Y248 Sugiyama SARS1 SARS SERS FMRKEVMQEVAQLsQFDEELyKVIGKGSEKSDDNSYDEKYL
P49773 Y109 Sugiyama HINT1 HINT PKCI1 PRKCNH1 GLNKGYRMVVNEGsDGGQsVyHVHLHVLGGRQMHWPPG___
P50395 Y203 Sugiyama GDI2 RABGDIB DFTGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsP
P50402 Y99 Sugiyama EMD EDMD STA KEDALLyQsKGyNDDyyEEsyFTTRTyGEPEsAGPSRAVRQ
P50502 Y185 Sugiyama ST13 AAG2 FAM10A1 HIP SNC6 NAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEAAHDL
P50990 Y30 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 GFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTTRTAYGPN
P50990 Y426 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 KRLVPGGGAtEIELAKQItsyGETCPGLEQyAIKKFAEAFE
P50990 Y436 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 EIELAKQItsyGETCPGLEQyAIKKFAEAFEAIPRALAENS
P50991 Y269 Sugiyama CCT4 CCTD SRB IQFCLSAPKTDMDNQIVVSDyAQMDRVLREERAYILNLVKQ
P50995 Y482 Sugiyama ANXA11 ANX11 sEtDLLDIRSEYKRMYGKsLyHDISGDtsGDyRKILLKICG
P50995 Y493 Sugiyama ANXA11 ANX11 YKRMYGKsLyHDISGDtsGDyRKILLKICGGND________
P51965 Y77 Sugiyama UBE2E1 UBCH6 ADITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
P52272 Y681 Sugiyama HNRNPM HNRPM NAGR1 PFDFTWKMLKDKFNECGHVLyADIKMENGKSKGCGVVKFEs
P52298 Y14 Sugiyama NCBP2 CBP20 PIG55 _______MSGGLLKALRsDsyVELSQYRDQHFRGDNEEQEK
P52565 Y156 Sugiyama ARHGDIA GDIA1 GVKIDKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYs
P52597 Y82 Sugiyama HNRNPF HNRPF GsEDDVKMALKKDRESMGHRyIEVFKSHRTEMDWVLKHsGP
P52655 Y365 Sugiyama GTF2A1 TF2A1 SKNKWKFHLKDGIMNLNGRDyIFSKAIGDAEW_________
P53634 Y438 Sugiyama CTSC CPPI SGMDYWIVKNsWGtGWGENGyFRIRRGtDECAIEsIAVAAt
P54577 Y388 Sugiyama YARS1 YARS LDIRVGKIITVEKHPDADsLyVEKIDVGEAEPRTVVSGLVQ
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55060 Y369 Sugiyama CSE1L CAS XPO2 VPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAACDL
P55196 Y1497 Sugiyama AFDN AF6 MLLT4 VIRELQPQQQPRTIERRDLQyItVsKEELssGDsLsPDPWK
P55209 Y106 Sugiyama NAP1L1 NRP VKCAQIEAKFyEEVHDLERKyAVLyQPLFDKRFEIINAIYE
P55209 Y110 Sugiyama NAP1L1 NRP QIEAKFyEEVHDLERKyAVLyQPLFDKRFEIINAIYEPTEE
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P55795 Y266 Sugiyama HNRNPH2 FTP3 HNRPH2 YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst
P56192 Y718 Sugiyama MARS1 MARS KVRIRDALRSILtISRHGNQyIQVNEPWKRIKGSEADRQRA
P56945 Y234 Sugiyama BCAR1 CAS CASS1 CRKAS VPtRVGQGyVyEAAQPEQDEyDIPRHLLAPGPQDIyDVPPV
P57053 Y41 Sugiyama H2BC12L H2BFS H2BS1 KAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
P57053 Y43 Sugiyama H2BC12L H2BFS H2BS1 QKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P58876 Y41 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
P58876 Y43 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P60174 Y209 Sugiyama TPI1 TPI LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG
P60174 Y48 Sugiyama TPI1 TPI tLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQNCy
P60660 Y29 Sugiyama MYL6 TAEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVL
P60660 Y86 Sugiyama MYL6 DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG
P60660 Y89 Sugiyama MYL6 HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI
P60709 Y198 Sugiyama ACTB LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y306 Sugiyama ACTB DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P60709 Y362 Sugiyama ACTB GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P60709 Y91 Sugiyama ACTB IEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAPLN
P60842 Y197 Sugiyama EIF4A1 DDX2A EIF4A KMFVLDEADEMLsRGFKDQIyDIFQKLNsNtQVVLLSATMP
P60842 Y48 Sugiyama EIF4A1 DDX2A EIF4A NEIVDSFDDMNLSESLLRGIyAyGFEKPsAIQQRAILPCIK
P60842 Y50 Sugiyama EIF4A1 DDX2A EIF4A IVDSFDDMNLSESLLRGIyAyGFEKPsAIQQRAILPCIKGy
P60842 Y70 Sugiyama EIF4A1 DDX2A EIF4A yGFEKPsAIQQRAILPCIKGyDVIAQAQsGtGKTATFAISI
P61024 Y19 Sugiyama CKS1B CKS1 PNAS-143 PNAS-16 __MSHKQIyysDKyDDEEFEyRHVMLPKDIAKLVPKTHLMs
P61024 Y7 Sugiyama CKS1B CKS1 PNAS-143 PNAS-16 ______________MSHKQIyysDKyDDEEFEyRHVMLPKD
P61081 Y172 Sugiyama UBE2M UBC12 VLQNNRRLFEQNVQRSMRGGyIGstyFERCLK_________
P61081 Y177 Sugiyama UBE2M UBC12 RRLFEQNVQRSMRGGyIGstyFERCLK______________
P61158 S232 Sugiyama ACTR3 ARP3 EVGIPPEQSLETAKAVKERysyVCPDLVKEFNKYDTDGSKW
P61158 Y231 Sugiyama ACTR3 ARP3 REVGIPPEQSLETAKAVKERysyVCPDLVKEFNKYDTDGSK
P61163 Y33 Sugiyama ACTR1A CTRN1 VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALE
P61163 Y38 Sugiyama ACTR1A CTRN1 SGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALEGDIFI
P61247 Y256 Sugiyama RPS3A FTE1 MFTL sssGKAtGDEtGAKVERADGyEPPVQEsV____________
P61313 Y6 Sugiyama RPL15 EC45 TCBAP0781 _______________MGAYKyIQELWRKKQSDVMRFLLRVR
P61313 Y62 Sugiyama RPL15 EC45 TCBAP0781 PTRPDKARRLGYKAKQGyVIyRIRVRRGGRKRPVPKGAtyG
P61604 Y76 Sugiyama HSPE1 KGGEIQPVsVKVGDKVLLPEyGGtKVVLDDKDyFLFRDGDI
P61604 Y88 Sugiyama HSPE1 GDKVLLPEyGGtKVVLDDKDyFLFRDGDILGKyVD______
P61981 S215 Sugiyama YWHAG HLAKtAFDDAIAELDtLNEDsyKDstLIMQLLRDNLtLWts
P61981 Y49 Sugiyama YWHAG NVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P62081 Y177 Sugiyama RPS7 HLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEFQL___
P62258 Y152 Sugiyama YWHAE LAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLG
P62258 Y214 Sugiyama YWHAE LAKAAFDDAIAELDtLsEEsyKDstLIMQLLRDNLtLWtsD
P62258 Y49 Sugiyama YWHAE KVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssIEQK
P62269 Y95 Sugiyama RPS18 D6S218E RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62280 Y55 Sugiyama RPS11 RYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILsG
P62312 Y72 Sugiyama LSM6 VNGQLKNKyGDAFIRGNNVLyIstQKRRM____________
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62750 Y144 Sugiyama RPL23A VNtLIRPDGEKKAYVRLAPDyDALDVANKIGII________
P62750 Y74 Sugiyama RPL23A LRRQPKYPRKSAPRRNKLDHyAIIKFPLTTEsAMKKIEDNN
P62807 Y41 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI KAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMG
P62807 Y43 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI QKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P62826 Y146 Sugiyama RAN ARA24 OK/SW-cl.81 IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR
P62899 Y108 Sugiyama RPL31 LSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN___
P62906 Y11 Sugiyama RPL10A NEDD6 __________MSSKVsRDtLyEAVREVLHGNQRKRRKFLET
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 Y79 Sugiyama PPIA CYPA GFMCQGGDFtRHNGTGGKsIyGEKFEDENFILKHtGPGILs
P62979 Y148 Sugiyama RPS27A UBA80 UBCEP1 AGVFMAsHFDRHyCGKCCLtyCFNKPEDK____________
P63104 Y149 Sugiyama YWHAZ LAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLG
P63104 Y19 Sugiyama YWHAZ __MDKNELVQKAKLAEQAERyDDMAACMKsVtEQGAELsNE
P63104 Y211 Sugiyama YWHAZ LAKtAFDEAIAELDtLsEEsyKDstLIMQLLRDNLtLWtsD
P63104 Y48 Sugiyama YWHAZ sVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssIEQK
P63173 Y41 Sugiyama RPL38 KSVKIKKNKDNVKFKVRCSRyLytLVItDKEKAEKLKQSLP
P63173 Y43 Sugiyama RPL38 VKIKKNKDNVKFKVRCSRyLytLVItDKEKAEKLKQSLPPG
P63220 Y53 Sugiyama RPS21 QMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRLA
P63261 Y198 Sugiyama ACTG1 ACTG LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y306 Sugiyama ACTG1 ACTG DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P63261 Y362 Sugiyama ACTG1 ACTG GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P63261 Y91 Sugiyama ACTG1 ACTG IEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAPLN
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67809 S209 Sugiyama YBX1 NSEP1 YB1 RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ
P67809 Y196 Sugiyama YBX1 NSEP1 YB1 sAPEGQAQQRRPyRRRRFPPyyMRRPYGRRPQysNPPVQGE
P67809 Y197 Sugiyama YBX1 NSEP1 YB1 APEGQAQQRRPyRRRRFPPyyMRRPYGRRPQysNPPVQGEV
P67809 Y208 Sugiyama YBX1 NSEP1 YB1 yRRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGE
P67809 Y72 Sugiyama YBX1 NSEP1 YB1 KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 Y93 Sugiyama ACTC1 ACTC IEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAPLN
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68133 Y93 Sugiyama ACTA1 ACTA IEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAPLN
P68363 Y432 Sugiyama TUBA1B GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
P80303 Y389 Sugiyama NUCB2 NEFA QKQKEELQRQHDQLEAQKLEyHQVIQQMEQKKLQQGIPPSG
P83731 Y11 Sugiyama RPL24 __________MKVELCsFsGyKIYPGHGRRYARTDGKVFQF
P84103 Y32 Sugiyama SRSF3 SFRS3 SRP20 VyVGNLGNNGNKtELERAFGyyGPLRSVWVARNPPGFAFVE
P84103 Y33 Sugiyama SRSF3 SFRS3 SRP20 yVGNLGNNGNKtELERAFGyyGPLRSVWVARNPPGFAFVEF
P98175 Y694 Sugiyama RBM10 DXS8237E GPATC9 GPATCH9 KIAA0122 QPISSLRDDERREsAtADAGyAILEKKGALAERQHTsMDLP
Q00169 Y140 Sugiyama PITPNA PITPN GTQENVHKLEPEAWKHVEAVyIDIADRSQVLSKDYKAEEDP
Q00341 Y40 Sugiyama HDLBP HBP VGL VPQQIKVAtLNsEEEsDPPtyKDAFPPLPEKAACLESAQEP
Q00534 Y13 Sugiyama CDK6 CDKN6 ________MEKDGLCRADQQyECVAEIGEGAyGKVFKARDL
Q00610 Y883 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 EARIHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsR
Q00610 Y899 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 LAKIyIDsNNNPERFLRENPyyDsRVVGKYCEKRDPHLACV
Q00610 Y900 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 AKIyIDsNNNPERFLRENPyyDsRVVGKYCEKRDPHLACVA
Q00653 Y247 Sugiyama NFKB2 LYT10 NLKISRMDKTAGSVRGGDEVyLLCDKVQKDDIEVRFYEDDE
Q00839 Y257 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 QKGGDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVE
Q00839 Y260 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED
Q01105 Y140 Sugiyama SET LTRVEVtEFEDIKsGyRIDFyFDENPyFENKVLSKEFHLNE
Q01105 Y146 Sugiyama SET tEFEDIKsGyRIDFyFDENPyFENKVLSKEFHLNEsGDPss
Q01130 Y44 Sugiyama SRSF2 SFRS2 RtsPDtLRRVFEKYGRVGDVyIPRDRYTKESRGFAFVRFHD
Q02809 Y434 Sugiyama PLOD1 LLH PLOD LWSNFWGALSADGYYARSEDyVDIVQGRRVGVWNVPYISNI
Q02878 T118 Sugiyama RPL6 TXREB1 GDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQHVR
Q02878 Y116 Sugiyama RPL6 TXREB1 VGGDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQH
Q04446 Y657 Sugiyama GBE1 RVGTALPGKFKIVLDSDAAEyGGHQRLDHSTDFFSEAFEHN
Q04837 Y73 Sugiyama SSBP1 SSBP PVTIFSLATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPG
Q04917 Y154 Sugiyama YWHAH YWHA1 LAEVASGEKKNsVVEAsEAAyKEAFEISKEQMQPTHPIRLG
Q04917 Y49 Sugiyama YWHAH YWHA1 AVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSIEQK
Q06830 Y116 Sugiyama PRDX1 PAGA PAGB TDPX2 GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK
Q07157 Y1128 Sugiyama TJP1 ZO1 NQHsQDLDSRQHPEESSERGyFPRFEEPAPLsyDsRPRYEQ
Q07157 Y1191 Sugiyama TJP1 ZO1 LRPEAQPHPsAGPKPAEsKQyFEQysRsyEQVPPQGFTSRA
Q07157 Y1355 Sugiyama TJP1 ZO1 KPPEDIVRSNHyDPEEDEEyyRKQLsyFDRRsFENKPPAHI
Q07666 Y145 Sugiyama KHDRBS1 SAM68 LtAEIEKIQKGDSKKDDEENyLDLFsHKNMKLKERVLIPVK
Q07955 Y37 Sugiyama SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 RIyVGNLPPDIRtKDIEDVFyKYGAIRDIDLKNRRGGPPFA
Q07955 Y82 Sugiyama SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 EDPRDAEDAVYGRDGyDYDGyRLRVEFPRSGRGTGRGGGGG
Q08043 Y229 Sugiyama ACTN3 KLRKDDPIGNLNTAFEVAEKyLDIPKMLDAEDIVNtPKPDE
Q08211 Y68 Sugiyama DHX9 DDX9 LKP NDH2 MGNSTNKKDAQSNAARDFVNyLVRINEIKsEEVPAFGVAsP
Q08J23 Y51 Sugiyama NSUN2 SAKI TRM4 EAGWEGGyPEIVKENKLFEHyyQELKIVPEGEWGQFMDALR
Q08J23 Y52 Sugiyama NSUN2 SAKI TRM4 AGWEGGyPEIVKENKLFEHyyQELKIVPEGEWGQFMDALRE
Q12996 Y708 Sugiyama CSTF3 NEDsDEDEEKGAVVPPVHDIyRARQQKRIR___________
Q13017 Y1109 Sugiyama ARHGAP5 RHOGAP5 DNyAEPIDTIFKQKGYsDEIyVVPDDsQNRIKIRNsFVNNt
Q13098 Y172 Sugiyama GPS1 COPS1 CSN1 YKGNSIKESIRRGHDDLGDHyLDCGDLSNALKCYSRARDYC
Q13144 Y495 Sugiyama EIF2B5 EIF2BE KDKVKMKGYNPAEVGAAGKGyLWKAAGMNMEEEEELQQNLW
Q13228 T38 Sugiyama SELENBP1 SBP AMKGPREEIVyLPCIyRNtGtEAPDyLATVDVDPKsPQyCQ
Q13228 Y28 Sugiyama SELENBP1 SBP CGPGySTPLEAMKGPREEIVyLPCIyRNtGtEAPDyLATVD
Q13228 Y43 Sugiyama SELENBP1 SBP REEIVyLPCIyRNtGtEAPDyLATVDVDPKsPQyCQVIHRL
Q13239 Y120 SIGNOR|PSP SLA SLAP SLAP1 LPDTKVGSFMIRESETKKGFySLSVRHRQVKHYRIFRLPNN
Q13239 Y258 SIGNOR|PSP SLA SLAP SLAP1 SLTSEDNTSFDRKKKSISLMyGGsKRKssFFSsPPyFED__
Q13239 Y273 SIGNOR|PSP SLA SLAP SLAP1 SISLMyGGsKRKssFFSsPPyFED_________________
Q13242 Y17 Sugiyama SRSF9 SFRS9 SRP30C ____MsGWADERGGEGDGRIyVGNLPTDVREKDLEDLFyKY
Q13242 Y214 Sugiyama SRSF9 SFRS9 SRP30C RsRSGsRGRDsPyQsRGsPHyFsPFRPy_____________
Q13263 Y133 Sugiyama TRIM28 KAP1 RNF96 TIF1B TVVDCPVCKQQCFSKDIVENyFMRDsGsKAATDAQDANQCC
Q13263 Y242 Sugiyama TRIM28 KAP1 RNF96 TIF1B ESCDTLTCRDCQLNAHKDHQyQFLEDAVRNQRKLLAsLVKR
Q13263 Y517 Sugiyama TRIM28 KAP1 RNF96 TIF1B LtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATGQPGtA
Q13283 Y19 Sugiyama G3BP1 G3BP __MVMEKPsPLLVGREFVRQyytLLNQAPDMLHRFYGKNss
Q13310 Y194 Sugiyama PABPC4 APP1 PABP4 KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF
Q13356 Y212 Sugiyama PPIL2 DPSYYLKNTNAETRETLQELyKEFKGDEILAATMKAPEKKK
Q13405 Y45 Sugiyama MRPL49 C11orf4 NOF1 OK/SW-cl.67 LLSQTQGPPDYPRFVEsVDEyQFVERLLPATRIPDPPKHEH
Q13435 Y591 Sugiyama SF3B2 SAP145 LHDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSD
Q13435 Y592 Sugiyama SF3B2 SAP145 HDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSDE
Q13442 S19 Sugiyama PDAP1 HASPP28 __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE
Q13442 Y17 Sugiyama PDAP1 HASPP28 ____MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREE
Q13442 Y70 Sugiyama PDAP1 HASPP28 DPKKEKKsLDsDEsEDEEDDyQQKRKGVEGLIDIENPNRVA
Q13480 Y659 Sugiyama GAB1 PPRKQKssGsGssVADERVDyVVVDQQKTLALKSTREAWTD
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13509 Y106 Sugiyama TUBB3 TUBB4 RPDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECEN
Q13546 Y384 Sugiyama RIPK1 RIP RIP1 EHPQEENEPSLQSKLQDEANyHLyGsRMDRQTKQQPRQNVA
Q13561 Y6 Sugiyama DCTN2 DCTN50 _______________MADPKyADLPGIARNEPDVYETSDLP
Q13573 Y292 Sugiyama SNW1 SKIIP SKIP GRGLQTVHINENFAKLAEALyIADRKAREAVEMRAQVERKM
Q13573 Y430 Sugiyama SNW1 SKIIP SKIP RLFNQSKGMDSGFAGGEDEIyNVyDQAWRGGKDMAQsIyRP
Q13573 Y433 Sugiyama SNW1 SKIIP SKIP NQSKGMDSGFAGGEDEIyNVyDQAWRGGKDMAQsIyRPSKN
Q13596 Y162 Sugiyama SNX1 QFDLTVGITDPEKIGDGMNAyVAyKVTTQTsLPLFRSKQFA
Q13619 Y259 Sugiyama CUL4A TNCLYAAEGQRLMQEREVPEyLNHVSKRLEEEGDRVITYLD
Q13642 Y149 Sugiyama FHL1 SLIM1 CSNCKQVIGtGSFFPKGEDFyCVtCHETKFAKHCVKCNKAI
Q13765 Y120 Sugiyama NACA HSD48 KNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAAA
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q13885 Y106 Sugiyama TUBB2A TUBB2 RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESES
Q14152 Y697 Sugiyama EIF3A EIF3S10 KIAA0139 LEKEKKELQERLKNQEKKIDyFERAKRLEEIPLIKSAYEEQ
Q14240 Y49 Sugiyama EIF4A2 DDX2B EIF4F NEIVDNFDDMNLKESLLRGIyAyGFEKPsAIQQRAIIPCIK
Q14240 Y51 Sugiyama EIF4A2 DDX2B EIF4F IVDNFDDMNLKESLLRGIyAyGFEKPsAIQQRAIIPCIKGy
Q14240 Y71 Sugiyama EIF4A2 DDX2B EIF4F yGFEKPsAIQQRAIIPCIKGyDVIAQAQsGtGKTATFAISI
Q14247 Y289 Sugiyama CTTN EMS1 FGGKFGVQsERQDsAAVGFDyKEKLAKHEsQQDySKGFGGK
Q14247 Y334 Sugiyama CTTN EMS1 KDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKtsNIRANF
Q14247 Y421 Sugiyama CTTN EMS1 tPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVsGtE
Q14247 Y453 Sugiyama CTTN EMS1 yRGPVsGtEPEPVysMEAADyREASSQQGLAYATEAVyESA
Q14257 Y311 Sugiyama RCN2 ERC55 NPDLFLtsEAtDyGRQLHDDyFyHDEL______________
Q14257 Y313 Sugiyama RCN2 ERC55 DLFLtsEAtDyGRQLHDDyFyHDEL________________
Q14257 Y54 Sugiyama RCN2 ERC55 ERRsDyDREALLGVQEDVDEyVKLGHEEQQKRLQAIIKKID
Q14566 Y598 Sugiyama MCM6 FARQFKPKISKESEDFIVEQyKHLRQRDGSGVTKSSWRITV
Q14568 Y283 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI
Q14671 Y83 Sugiyama PUM1 KIAA0099 PUMH1 SPVPGSIGVAGRsQDDAMVDyFFQRQHGEQLGGGGsGGGGy
Q14677 Y114 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 SERVVTSAREHIyDLRSLENyHFVDEHGKDQGINIRQKVKE
Q14696 Y58 Sugiyama MESD KIAA0081 MESDC2 MESDM UNQ1911/PRO4369 PGTPDESTPPPRKKKKDIRDyNDADMARLLEQWEKDDDIEE
Q14697 Y489 Sugiyama GANAB G2AN KIAA0088 PHIKVDSGyRVHEELRNLGLyVKtRDGSDyEGWCWPGSAGY
Q14697 Y60 Sugiyama GANAB G2AN KIAA0088 tCEEssFCKRQRsIRPGLsPyRALLDSLQLGPDSLTVHLIH
Q14974 Y529 Sugiyama KPNB1 NTF97 KLLETTDRPDGHQNNLRSSAyEsLMEIVKNSAKDCYPAVQK
Q15056 Y101 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 FKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRKQ
Q15056 Y86 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 sIRsVRLVRDKDTDKFKGFCyVEFDEVDsLKEALtyDGALL
Q15181 Y169 Sugiyama PPA1 IOPPP PP EGETDWKVIAINVDDPDAANyNDINDVKRLKPGYLEATVDW
Q15181 Y17 Sugiyama PPA1 IOPPP PP ____MSGFSTEERAAPFsLEyRVFLKNEKGQyIsPFHDIPI
Q15293 Y115 Sugiyama RCN1 RCN GDGFVttEELKtWIKRVQKRyIFDNVAKVWKDYDRDKDDKI
Q15293 Y140 Sugiyama RCN1 RCN VAKVWKDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssD
Q15293 Y147 Sugiyama RCN1 RCN YDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFKKM
Q15293 Y148 Sugiyama RCN1 RCN DRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFKKML
Q15293 Y228 Sugiyama RCN1 RCN VLEtLEDIDKNGDGFVDQDEyIADMFSHEENGPEPDWVLSE
Q15293 Y278 Sugiyama RCN1 RCN LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE
Q15369 Y18 Sugiyama ELOC TCEB1 ___MDGEEKtyGGCEGPDAMyVKLISSDGHEFIVKREHALt
Q15427 Y16 Sugiyama SF3B4 SAP49 _____MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFLQA
Q15459 Y456 Sugiyama SF3A1 SAP114 PRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAERRtDI
Q15527 Y123 Sugiyama SURF2 GRRYQRALCKYEECQKQGVEyVPACLVHRRRRREDQMDGDG
Q15555 Y268 Sugiyama MAPRE2 RP1 NEQVHsLKLALEGVEKERDFyFGKLREIELLCQEHGQENDD
Q15631 Y210 Sugiyama TSN sLRKRYDGLKYDVKKVEEVVyDLSIRGFNKETAAACVEK__
Q15650 Y289 Sugiyama TRIP4 RQT4 LLEFDRtsIRRtQVIDDESDyFASDSNQWLSKLERETLQKR
Q15650 Y345 Sugiyama TRIP4 RQT4 KVTIDFAGRKILEEENsLAEyHSRLDETIQAIANGTLNQPL
Q15691 Y217 Sugiyama MAPRE1 MQQVNVLKLtVEDLEKERDFyFGKLRNIELICQENEGENDP
Q15785 Y54 Sugiyama TOMM34 URCC3 RALRVLQAQGssDPEEEsVLysNRAACHLKDGNCRDCIKDC
Q16719 Y441 Sugiyama KYNU RGVVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsA
Q16719 Y448 Sugiyama KYNU RNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAETKN___
Q16719 Y47 Sugiyama KYNU ERVALHLDEEDKLRHFRECFyIPKIQDLPPVDLSLVNKDEN
Q16778 Y41 Sugiyama H2BC21 H2BFQ HIST2H2BE KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKAMG
Q16778 Y43 Sugiyama H2BC21 H2BFQ HIST2H2BE QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKAMGIM
Q32MZ4 Y597 Sugiyama LRRFIP1 GCF2 TRIP KKKKsPVPVETLKDVKKELtyQNTDLsEIKEEEQVKstDRK
Q53H82 Y121 Sugiyama LACTB2 CGI-83 IKKLPRNPQREEIIGNGEQQyVyLKDGDVIKTEGATLRVLY
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF3 Y58 Sugiyama HSP90B2P GRP94B GRP94P1 TRAP1 VTFKSILFVPTFVPRGLFDEyGsKKSDYIKLYVRCVFITDD
Q58FF6 Y167 Sugiyama HSP90AB4P GEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIGCL
Q58FF6 Y32 Sugiyama HSP90AB4P KEIFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDII
Q58FF7 Y171 Sugiyama HSP90AB3P HSP90BC GEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIGyP
Q58FF7 Y492 Sugiyama HSP90AB3P HSP90BC TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR
Q58FF7 Y56 Sugiyama HSP90AB3P HSP90BC EEIFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FF8 Y198 Sugiyama HSP90AB2P HSP90BB DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI
Q58FF8 Y260 Sugiyama HSP90AB2P HSP90BB VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW
Q58FF8 Y56 Sugiyama HSP90AB2P HSP90BB KEIFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FG0 Y177 Sugiyama HSP90AA5P HSP90AE GQLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQ
Q58FG0 Y178 Sugiyama HSP90AA5P HSP90AE QLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQK
Q5JTH9 Y1251 Sugiyama RRP12 KIAA0690 AEYKAKKAKGDVKKKGRPDPyAyIPLNRSKLNRRKKMKLQG
Q5QNW6 Y41 Sugiyama H2BC18 HIST2H2BF KVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q5QNW6 Y43 Sugiyama H2BC18 HIST2H2BF QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q5SW79 Y364 Sugiyama CEP170 FAM68A KAB KIAA0470 QMLWERTEEDsKsIKsDVPVyLKRLKGNKHDDGtQsDsENA
Q5T200 Y592 Sugiyama ZC3H13 KIAA0853 EKGSRGsRGsQIDsHSSNSNyHDSWETRSSYPERDRYPERD
Q5VV41 Y216 Sugiyama ARHGEF16 EPHEXIN4 NBR KKTLGRKRGHKGsFKDDPQLyQEIQERGLNtsQEsDDDILD
Q6DN03 Y41 Sugiyama H2BC20P HIST2H2BC KAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMG
Q6DN03 Y43 Sugiyama H2BC20P HIST2H2BC QKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMGIM
Q6DRA6 Y41 Sugiyama H2BC19P HIST2H2BD KAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMG
Q6DRA6 Y43 Sugiyama H2BC19P HIST2H2BD QKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMGIM
Q6NVY1 Y247 Sugiyama HIBCH EDLLALKsPSKENIAsVLENyHtESKIDRDKSFILEEHMDK
Q6QNY0 Y40 Sugiyama BLOC1S3 BLOS3 GEAtEtDsERsAsssEEEELyLGPSGPTRGRPTGLRVAGEA
Q6S8J3 Y1062 Sugiyama POTEE A26C1A POTE2 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q6S8J3 Y791 Sugiyama POTEE A26C1A POTE2 MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAPLN
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6UN15 Y453 Sugiyama FIP1L1 FIP1 RHE HLPGSAPsWPSLVDTSKQWDyyARREKDRDRERDRDRERDR
Q6ZSR9 Y28 Sugiyama None LYPDPSRVPGTKTQNNLESDyLARDGPSSNSSFHSSEEEGT
Q71RC2 Y425 Sugiyama LARP4 PP13296 SRNFPAERHNPTVTGHQEQtyLQKETSTLQVEQNGDYGRGR
Q71U36 Y432 Sugiyama TUBA1A TUBA3 GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
Q7KZF4 Y476 Sugiyama SND1 TDRD11 SKGLATVIRYRQDDDQRssHyDELLAAEARAIKNGKGLHSK
Q7RTV0 Y100 Sugiyama PHF5A KDRDGCPKIVNLGSsKTDLFyERKKYGFKKR__________
Q7Z5J4 Y305 Sugiyama RAI1 KIAA1820 QQQQQQQALQSRHHAQETLHyQNLAKYQHYGQQGQGYCQPD
Q86SX6 Y88 Sugiyama GLRX5 C14orf87 GFSNAVVQILRLHGVRDyAAyNVLDDPELRQGIKDYSNWPT
Q86V81 Y250 Sugiyama ALYREF ALY BEF THOC4 AGRNSKQQLsAEELDAQLDAyNARMDts_____________
Q86XP3 Y160 Sugiyama DDX42 ERKNVKGIRDDIEEEDDQEAyFRYMAENPtAGVVQEEEEDN
Q8IV50 T210 Sugiyama LYSMD2 STQAAKKLKEESRDEEsPyAtSLyHs_______________
Q8IWX8 Y894 Sugiyama CHERP DAN26 SCAF6 GDVRDKWDQYKGVGVALDDPyENyRRNKsysFIARMKARDE
Q8IWX8 Y897 Sugiyama CHERP DAN26 SCAF6 RDKWDQYKGVGVALDDPyENyRRNKsysFIARMKARDECK_
Q8IWX8 Y903 Sugiyama CHERP DAN26 SCAF6 YKGVGVALDDPyENyRRNKsysFIARMKARDECK_______
Q8IXH6 Y211 Sugiyama TP53INP2 C20orf110 DOR PINH RQNRARESRPRRSKNQSsFIyQPCQRQFNY___________
Q8IY92 T1561 Sugiyama SLX4 BTBD12 KIAA1784 KIAA1987 GLEtPKGANRKKNLPPKVPItPMPQYSIMEtPVLKKELDRF
Q8IY92 T1571 Sugiyama SLX4 BTBD12 KIAA1784 KIAA1987 KKNLPPKVPItPMPQYSIMEtPVLKKELDRFGVRPLPKRQM
Q8IZP0 Y23 Sugiyama ABI1 SSH3BP1 ELQMLLEEEIPSGKRALIEsyQNLTRVADyCENNyIQATDK
Q8N0Y7 S137 Sugiyama PGAM4 PGAM3 RsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSYESPK
Q8N0Y7 Y92 Sugiyama PGAM4 PGAM3 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
Q8N1G4 Y257 Sugiyama LRRC47 KIAA1185 LRDKRLEKMVSGCQTRSILEyLRVGGRGGGKGKGRAEGSEK
Q8N257 Y41 Sugiyama H2BC26 H2BU1 HIST3H2BB KAQKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKAMG
Q8N257 Y43 Sugiyama H2BC26 H2BU1 HIST3H2BB QKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKAMGIM
Q8N5P1 Y97 Sugiyama ZC3H8 ZC3HDC8 sDNDICsQEsEDNFAKELQQyIQAREMANAAQPEESTKKEG
Q8N684 Y451 Sugiyama CPSF7 SRESSRRHRDLLHNEDRHDDyFQERNREHERHRDRERDRHH
Q8N6H7 Y278 Sugiyama ARFGAP2 ZNF289 Nbla10535 QAADAKKQAEESMVASMRLAyQELQIDRKKEEKKLQNLEGK
Q8N7H5 Y311 Sugiyama PAF1 PD2 IAREYNWNVKNKASKGyEENyFFIFREGDGVyyNELETRVR
Q8NBF2 Y39 Sugiyama NHLRC2 TSLEYALLDAVTQQEKDSLVyQyLQKVDGWEQDLSVPEFPE
Q8NBS9 Y251 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 ALGLEHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDG
Q8NBS9 Y289 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 RDGKKVDQYKGKRDLEsLREyVEsQLQRTETGATETVTPSE
Q8NDI1 Y585 Sugiyama EHBP1 KIAA0903 NACSIN TYKVGNYETDTNssVDQEKFyAELSDLKREPELQQPISGAV
Q8NFI4 Y185 Sugiyama ST13P5 FAM10A5 NAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEAAHDL
Q8NI22 Y135 Sugiyama MCFD2 SDNSF DELINIIDGVLRDDDKNNDGyIDyAEFAKSLQ_________
Q8NI22 Y138 Sugiyama MCFD2 SDNSF INIIDGVLRDDDKNNDGyIDyAEFAKSLQ____________
Q8TD19 Y52 Sugiyama NEK9 KIAA1995 NEK8 NERCC PSASQGPRAGGGAAEQEELHyIPIRVLGRGAFGEAtLyRRT
Q8TD19 Y845 Sugiyama NEK9 KIAA1995 NEK8 NERCC PDsPsPLsAAFsEsEKDTLPyEELQGLKVAsEAPLEHKPQV
Q8TDD1 Y681 Sugiyama DDX54 GPNRGAKRRREEARQRDQEFyIPyRPKDFDSERGLsIsGEG
Q8TEW0 Y388 Sugiyama PARD3 PAR3 PAR3A QLSQSEKNNyyssRFsPDsQyIDNRSVNSAGLHTVQRAPRL
Q8WUA2 Y401 Sugiyama PPIL4 TSKKHKKKTHHCsEEKEDEDyMPIKNTNQDIYREMGFGHYE
Q8WVC0 Y374 Sugiyama LEO1 RDL PETRIEVEIPKVNTDLGNDLyFVKLPNFLSVEPRPFDPQYY
Q8WVJ2 Y145 Sugiyama NUDCD2 ERFQKENPGFDFsGAEIsGNytKGGPDFsNLEK________
Q8WX93 Y731 Sugiyama PALLD KIAA0992 CGI-151 PMSALASRsAPAMQssGsFNyARPKQFIAAQNLGPAsGHGt
Q8WYP5 Y1790 Sugiyama AHCTF1 ELYS TMBS62 MSTP108 QSVRKKTRKAKEISEASENIySDVRGLsQNQQIPQNsVtPR
Q92796 S678 Sugiyama DLG3 KIAA1232 HTTRPRRDNEVDGQDyHFVVsREQMEKDIQDNKFIEAGQFN
Q92796 Y673 Sugiyama DLG3 KIAA1232 GSCVPHTTRPRRDNEVDGQDyHFVVsREQMEKDIQDNKFIE
Q92878 Y1162 Sugiyama RAD50 EINKIIRDLWRSTYRGQDIEyIEIRSDADENVSASDKRRNY
Q92945 Y626 Sugiyama KHSRP FUBP2 EPPQPPPTGQSDYTKAWEEyyKKIGQQPQQPGAPPQQDytK
Q93079 Y41 Sugiyama H2BC9 H2BFJ HIST1H2BH KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q93079 Y43 Sugiyama H2BC9 H2BFJ HIST1H2BH QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q969T4 Y91 Sugiyama UBE2E3 UBCE4 UBCH9 AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
Q96AE4 Y590 Sugiyama FUBP1 DQQNPAPAGQVDYTKAWEEyyKKMGQAVPAPTGAPPGGQPD
Q96AE4 Y626 Sugiyama FUBP1 GGQPDYSAAWAEYYRQQAAyyAQtsPQGMPQHPPAPQGQ__
Q96C90 Y29 Sugiyama PPP1R14B PLCB3N PNG GAALAAPAPGPGsGGPGPRVyFQsPPGAAGEGPGGADDEGP
Q96CT7 Y38 Sugiyama CCDC124 RRAEAKAAADAKKQKELEDAyWKDDDKHVMRKEQRKEEKEK
Q96D46 Y459 Sugiyama NMD3 CGI-07 YQDFLEDLEEDEAIRKNVNIyRDsAIPVEsDtDDEGAPRIS
Q96F86 Y258 Sugiyama EDC3 LSM16 YJDC YJEFN2 PP844 NERPTRYRHDENILESEPIVyRRIIVPHNVSKEFCTDSGLV
Q96GX9 Y57 Sugiyama APIP CGI-29 HLGWVTGTGGGISLKHGDEIyIAPsGVQKERIQPEDMFVCD
Q96HE7 Y178 Sugiyama ERO1A ERO1L UNQ434/PRO865 HDDSSDNFCEADDIQsPEAEyVDLLLNPERYTGYKGPDAWK
Q96IK1 Y82 Sugiyama BOD1 FAM44B RGLFDSFRRDCLADVDTKPAyQNLRQKVDNFVStHLDKQEW
Q96LR5 Y85 Sugiyama UBE2E2 UBCH8 AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
Q96NB3 Y315 Sugiyama ZNF830 CCDC16 EDEEGRLDRQIGEIDEQIECyRRVEKLRNRQDEIKNKLKEI
Q96QC0 Y512 Sugiyama PPP1R10 CAT53 FB19 PNUTS GILQELFLNKESPHEPDPEPyEPIPPKLIPLDEECSMDETP
Q96QK1 Y507 Sugiyama VPS35 MEM3 TCCCTA00141 EQSLVGRFIHLLRsEDPDQQyLILNTARKHFGAGGNQRIRF
Q99470 Y69 Sugiyama SDF2 GSGSGQQSVTGVTSVDDSNSyWRIRGKSATVCERGTPIKCG
Q99614 Y212 Sugiyama TTC1 TPR1 ILRRAELYEKTDKLDEALEDyKSILEKDPSIHQAREACMRL
Q99614 Y96 Sugiyama TTC1 TPR1 ADKVENKsNEDVNssELDEEyLIELEKNMSDEEKQKRREES
Q99733 Y95 Sugiyama NAP1L4 NAP2 VRCAHIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVE
Q99733 Y99 Sugiyama NAP1L4 NAP2 HIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVEPtDA
Q99798 Y544 Sugiyama ACO2 LEAPDADELPKGEFDPGQDtyQHPPKDSsGQHVDVsPtsQR
Q99848 Y265 Sugiyama EBNA1BP2 EBP2 NQKFGFGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPG
Q99877 Y41 Sugiyama H2BC15 H2BFD HIST1H2BN KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99877 Y43 Sugiyama H2BC15 H2BFD HIST1H2BN QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q99879 Y41 Sugiyama H2BC14 H2BFE HIST1H2BM KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99879 Y43 Sugiyama H2BC14 H2BFE HIST1H2BM QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q99880 Y41 Sugiyama H2BC13 H2BFC HIST1H2BL KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99880 Y43 Sugiyama H2BC13 H2BFC HIST1H2BL QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q99961 Y57 Sugiyama SH3GL1 CNSA1 SH3D2B EKKVDVTSKAVTEVLARTIEyLQPNPAsRAKLTMLNTVSKI
Q99962 Y57 Sugiyama SH3GL2 CNSA2 SH3D2A ERKVDVTSRAVMEIMTKTIEyLQPNPAsRAKLSMINTMsKI
Q9BPX3 Y929 Sugiyama NCAPG CAPG NYMEL3 QDATLTTTTFQNEDEKNKEVyMtPLRGVKATQASKSTQLKT
Q9BQE3 Y432 Sugiyama TUBA1C TUBA6 GMEEGEFSEAREDMAALEKDyEEVGADsADGEDEGEEy___
Q9BRK5 Y162 Sugiyama SDF4 CAB45 PSEC0034 sKTHFRAVDPDGDGHVsWDEyKVKFLASKGHSEKEVADAIR
Q9BS40 Y20 Sugiyama LXN _MEIPPTNYPASRAALVAQNyINyQQGTPHRVFEVQKVKQA
Q9BS40 Y23 Sugiyama LXN IPPTNYPASRAALVAQNyINyQQGTPHRVFEVQKVKQAsME
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BVA1 Y106 Sugiyama TUBB2B RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESES
Q9BW71 Y111 Sugiyama HIRIP3 RKRFRFNsEsEsGsEASSPDyFGPPAKNGVAAEVsPAKEEN
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BYX7 Y362 Sugiyama POTEKP ACTBL3 FKSG30 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q9BYX7 Y91 Sugiyama POTEKP ACTBL3 FKSG30 MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAPLN
Q9C0C2 Y1122 Sugiyama TNKS1BP1 KIAA1741 TAB182 FsPGQQDWsRDFCIEASERsyQFGIIGNDRVsGAGFsPssK
Q9GZY6 Y110 EPSD|PSP LAT2 LAB NTAL WBS15 WBSCR15 WBSCR5 HSPC046 PASSRyQNFSKGsRHGsEEAyIDPIAMEyyNWGRFSKPPED
Q9GZY6 Y118 EPSD|PSP LAT2 LAB NTAL WBS15 WBSCR15 WBSCR5 HSPC046 FSKGsRHGsEEAyIDPIAMEyyNWGRFSKPPEDDDANsyEN
Q9H1E3 Y146 Sugiyama NUCKS1 NUCKS JC7 QEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPERKE
Q9H2H8 T140 Sugiyama PPIL3 KVIDGLETLDELEKLPVNEKtyRPLNDVHIKDItIHANPFA
Q9H788 Y131 Sugiyama SH2D4A PPP1R38 SH2A EEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKDIWKKVAE
Q9H814 Y57 Sugiyama PHAX RNUXA GDsAMRAFQNTAtACAPVSHyRAVESVDSSEESFSDSDDDS
Q9HC35 Y226 Sugiyama EML4 C2orf2 EMAPL4 PKVTKTADKHKDVIINQEGEyIKMFMRGRPItMFIPSDVDN
Q9HCG8 Y45 Sugiyama CWC22 KIAA1604 NCM RNssPEDRYEEQERsPRDRDyFDYsRsDYEHSRRGRsYDsS
Q9HCN8 Y81 Sugiyama SDF2L1 UNQ1941/PRO4424 GSGSGQQSVtGVEAsDDANSyWRIRGGSEGGCPRGSPVRCG
Q9NP61 Y432 Sugiyama ARFGAP3 ARFGAP1 ENTDEAQKKFGNVKAIssDMyFGRQsQADYETRARLERLsA
Q9NPQ8 Y446 Sugiyama RIC8A MAGGRPEGQysEDEDtDtDEyKEAKAsINPVTGRVEEKPPN
Q9NQW7 Y588 Sugiyama XPNPEP1 XPNPEPL XPNPEPL1 QTKMIDVDSLTDKECDWLNNyHLtCRDVIGKELQKQGRQEA
Q9NRX4 Y52 Sugiyama PHPT1 PHP14 CGI-202 HSPC141 RSGAPAAESKEIVRGYKWAEyHADIyDKVSGDMQKQGCDCE
Q9NRX4 Y57 Sugiyama PHPT1 PHP14 CGI-202 HSPC141 AAESKEIVRGYKWAEyHADIyDKVSGDMQKQGCDCECLGGG
Q9NUL3 Y326 Sugiyama STAU2 MNPISRLAQIQQAKKEKEPDyVLLSERGMPRRREFVMQVKV
Q9NVS9 Y256 Sugiyama PNPO LPtGDsPLGPMTHRGEEDWLyERLAP_______________
Q9NYF8 Y408 Sugiyama BCLAF1 BTF KIAA0164 EsGKQKFNDsEGDDtEEtEDyRQFRKsVLADQGKsFATAsH
Q9NZB2 Y9 Sugiyama FAM120A C9orf10 KIAA0183 OSSA ____________MGVQGFQDyIEKHCPsAVVPVELQKLARG
Q9UBQ7 Y255 Sugiyama GRHPR GLXR MSTP035 KETAVFINISRGDVVNQDDLyQALAsGKIAAAGLDVtsPEP
Q9UBR2 Y76 Sugiyama CTSZ YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA
Q9UFG5 Y63 Sugiyama C19orf25 EDPPVPFRMMEDAEAPGEQLyQQSRAYVAANQRLQQAGNVL
Q9UGY1 Y30 Sugiyama NOL12 DGDDRRPRLVLsFDEEKRREyLTGFHKRKVERKKAAIEEIK
Q9UI15 Y192 Sugiyama TAGLN3 NP25 NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________
Q9UIQ6 Y70 Sugiyama LNPEP OTASE GsRLLVRGLGEHEMEEDEEDyEssAKLLGMsFMNRssGLRN
Q9UJU6 Y16 Sugiyama DBNL CMAP SH3P7 PP5423 _____MAANLSRNGPALQEAyVRVVtEKsPtDWALFTyEGN
Q9UKY7 Y244 Sugiyama CDV3 H41 NRGRDEVSKNQALKLQLDNQyAVLENQKSSHSQYN______
Q9ULF5 Y596 Sugiyama SLC39A10 KIAA1265 ZIP10 RLNEtELtDLEGQQEsPPKNyLCIEEEKIIDHsHsDGLHtI
Q9UMS0 Y194 Sugiyama NFU1 HIRIP5 CGI-33 KELLDTRIRPTVQEDGGDVIyKGFEDGIVQLKLQGSCTSCP
Q9UMX5 Y65 Sugiyama NENF CIR2 SPUF RLFtEEELARYGGEEEDQPIyLAVKGVVFDVtSGKEFYGRG
Q9UNF0 Y267 Sugiyama PACSIN2 VLLEVQKHLDLSNVAGYKAIyHDLEQsIRAADAVEDLRWFR
Q9UNP9 Y143 Sugiyama PPIE CYP33 KAETQEGEPIAKKARSNPQVyMDIKIGNKPAGRIQMLLRSD
Q9UNZ2 Y167 Sugiyama NSFL1C UBXN2C PRPFAGGGYRLGAAPEEEsAyVAGEKRQHssQDVHVVLKLW
Q9UPQ0 Y446 Sugiyama LIMCH1 KIAA1102 LHEAYKNARsQEEAEGILQQyIERFTISEAVLERLEMPKIL
Q9UQ80 Y98 Sugiyama PA2G4 EBP1 TSISVNNCVCHFsPLKSDQDyILKEGDLVKIDLGVHVDGFI
Q9Y281 T91 Sugiyama CFL2 FVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPESAPL
Q9Y281 Y82 Sugiyama CFL2 DTVEDPYtsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFI
Q9Y281 Y89 Sugiyama CFL2 tsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPESA
Q9Y2T7 Y107 Sugiyama YBX2 CSDA3 MSY2 KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
Q9Y2W2 Y124 Sugiyama WBP11 NPWBP SIPP1 SNP70 YKELRKLEVEYEQKRAQLSQyFDAVKNAQHVEVESIPLPDM
Q9Y3C1 Y118 Sugiyama NOP16 CGI-117 HSPC111 EAEASLPEKKGNTLSRDLIDyVRYMVENHGEDYKAMARDEK
Q9Y3F4 Y114 Sugiyama STRAP MAWD UNRIP LMTLAHKHIVKtVDFtQDSNyLLtGGQDKLLRIYDLNKPEA
Q9Y3P9 Y472 Sugiyama RABGAP1 HSPC094 FFLKLKQIKQRERKNNTDTLyEVVCLESESERERRKTTAsP
Q9Y3U8 Y53 Sugiyama RPL36 LTKHTKFVRDMIREVCGFAPyERRAMELLKVSKDKRALKFI
Q9Y490 Y127 Sugiyama TLN1 KIAA1027 TLN TVTDMLMTICARIGITNHDEysLVRELMEEKKEEItGtLRK
Q9Y4H2 Y919 Sugiyama IRS2 PSLPSMHEYPLPPEPKsPGEyINIDFGEPGARLsPPAPPLL
Q9Y5Q8 Y393 Sugiyama GTF3C5 CDABP0017 SGtsGARKPASSKYKLKDSVyIFREGALPPYRQMFYQLCDL
Q9Y5S9 Y54 Sugiyama RBM8A RBM8 HSPC114 MDS014 KRKGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWI
Q9Y639 Y216 Sugiyama NPTN SDFR1 SDR1 KNASNMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKA
Q9Y639 Y220 Sugiyama NPTN SDFR1 SDR1 NMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKAAPDI
Q9Y696 Y244 Sugiyama CLIC4 AysRDEFtNtCPsDKEVEIAysDVAKRLTK___________
Site Promiscuity

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.851252e-11 10.733 1 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 2.655370e-09 8.576 1 1
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 6.848111e-09 8.164 1 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.561592e-08 7.448 1 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.307340e-08 7.275 1 1
Negative regulation of the PI3K/AKT network R-HSA-199418 9.723116e-08 7.012 1 0
IGF1R signaling cascade R-HSA-2428924 1.389602e-07 6.857 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 1.558615e-07 6.807 0 0
RAF/MAP kinase cascade R-HSA-5673001 4.029762e-07 6.395 1 1
MAPK1/MAPK3 signaling R-HSA-5684996 5.397040e-07 6.268 1 0
Signaling by LTK R-HSA-9842663 1.148826e-06 5.940 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.680930e-06 5.774 0 0
Signaling by NTRKs R-HSA-166520 2.842069e-06 5.546 0 0
MAPK family signaling cascades R-HSA-5683057 3.648052e-06 5.438 1 0
Signaling by ERBB2 R-HSA-1227986 1.226127e-05 4.911 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.222424e-05 4.913 1 1
Signaling by KIT in disease R-HSA-9669938 1.695382e-05 4.771 1 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 1.695382e-05 4.771 1 1
Signal Transduction R-HSA-162582 1.791392e-05 4.747 1 0
Signaling by SCF-KIT R-HSA-1433557 2.491272e-05 4.604 1 1
Interleukin-15 signaling R-HSA-8983432 3.358467e-05 4.474 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.688435e-05 4.433 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 3.779950e-05 4.423 0 0
Signaling by Erythropoietin R-HSA-9006335 4.863362e-05 4.313 0 0
Regulation of KIT signaling R-HSA-1433559 5.288417e-05 4.277 1 1
Intracellular signaling by second messengers R-HSA-9006925 5.490286e-05 4.260 1 0
Axon guidance R-HSA-422475 5.998215e-05 4.222 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 7.052646e-05 4.152 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 1.017437e-04 3.992 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 1.298876e-04 3.886 0 0
Nervous system development R-HSA-9675108 1.320365e-04 3.879 0 0
STAT5 Activation R-HSA-9645135 1.474940e-04 3.831 0 0
Erythropoietin activates STAT5 R-HSA-9027283 1.474940e-04 3.831 0 0
Insulin receptor signalling cascade R-HSA-74751 1.632050e-04 3.787 0 0
Activation of TRKA receptors R-HSA-187015 2.006983e-04 3.697 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.479335e-04 3.606 0 0
EPHB-mediated forward signaling R-HSA-3928662 3.030435e-04 3.518 0 0
Growth hormone receptor signaling R-HSA-982772 3.243943e-04 3.489 0 0
Signaling by Interleukins R-HSA-449147 3.034328e-04 3.518 0 0
Signal attenuation R-HSA-74749 4.304032e-04 3.366 0 0
PI3K/AKT activation R-HSA-198203 4.304032e-04 3.366 0 0
Interleukin-7 signaling R-HSA-1266695 4.164222e-04 3.380 0 0
Signaling by Leptin R-HSA-2586552 4.304032e-04 3.366 0 0
PI3K Cascade R-HSA-109704 4.962603e-04 3.304 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 5.332534e-04 3.273 0 0
Interleukin-2 signaling R-HSA-9020558 5.332534e-04 3.273 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 5.257191e-04 3.279 0 0
PECAM1 interactions R-HSA-210990 5.332534e-04 3.273 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 6.506227e-04 3.187 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 6.506227e-04 3.187 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 6.540124e-04 3.184 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 7.832908e-04 3.106 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 7.832908e-04 3.106 0 0
IRS-mediated signalling R-HSA-112399 8.249713e-04 3.084 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 9.336801e-04 3.030 0 0
EPH-Ephrin signaling R-HSA-2682334 1.007679e-03 2.997 0 0
Signaling by Insulin receptor R-HSA-74752 1.007679e-03 2.997 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 1.170379e-03 2.932 0 0
Erythropoietin activates RAS R-HSA-9027284 1.280435e-03 2.893 0 0
RET signaling R-HSA-8853659 1.392198e-03 2.856 0 0
TRKA activation by NGF R-HSA-187042 1.448385e-03 2.839 0 0
MET activates PTPN11 R-HSA-8865999 1.448385e-03 2.839 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 1.701321e-03 2.769 0 0
Signaling by ALK R-HSA-201556 1.777549e-03 2.750 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.070689e-03 2.684 0 0
FLT3 Signaling R-HSA-9607240 2.072067e-03 2.684 0 0
Interleukin-2 family signaling R-HSA-451927 1.920903e-03 2.716 0 0
MTF1 activates gene expression R-HSA-5660489 2.070689e-03 2.684 0 0
Cytokine Signaling in Immune system R-HSA-1280215 2.193098e-03 2.659 0 0
Ephrin signaling R-HSA-3928664 2.199635e-03 2.658 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 2.398682e-03 2.620 0 0
Regulation of signaling by CBL R-HSA-912631 2.479265e-03 2.606 0 0
IRS activation R-HSA-74713 2.798205e-03 2.553 0 0
NTRK2 activates RAC1 R-HSA-9032759 2.798205e-03 2.553 0 0
Reelin signalling pathway R-HSA-8866376 2.798205e-03 2.553 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.779926e-03 2.556 0 0
NGF-independant TRKA activation R-HSA-187024 3.628586e-03 2.440 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 3.628586e-03 2.440 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.446337e-03 2.463 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 3.700513e-03 2.432 0 0
Degradation of CDH1 R-HSA-9766229 3.818745e-03 2.418 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.446337e-03 2.463 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 3.628586e-03 2.440 0 0
Interleukin receptor SHC signaling R-HSA-912526 4.202629e-03 2.376 0 0
Immune System R-HSA-168256 4.344629e-03 2.362 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 4.615555e-03 2.336 0 0
Sema4D in semaphorin signaling R-HSA-400685 5.052196e-03 2.297 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 4.615555e-03 2.336 0 0
Adherens junctions interactions R-HSA-418990 5.137188e-03 2.289 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.615555e-03 2.336 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 5.588735e-03 2.253 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 5.588735e-03 2.253 0 0
SOS-mediated signalling R-HSA-112412 5.588735e-03 2.253 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.588735e-03 2.253 0 0
Packaging Of Telomere Ends R-HSA-171306 5.998080e-03 2.222 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 5.998080e-03 2.222 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 5.306887e-03 2.275 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.673884e-03 2.246 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.673884e-03 2.246 0 0
Regulation of CDH1 Function R-HSA-9764561 6.036909e-03 2.219 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 6.221290e-03 2.206 0 0
Drug resistance of FLT3 mutants R-HSA-9702506 1.093189e-02 1.961 0 0
Drug resistance of KIT mutants R-HSA-9669937 1.093189e-02 1.961 1 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.093189e-02 1.961 0 0
KIT mutants bind TKIs R-HSA-9669921 1.093189e-02 1.961 1 1
FLT3 mutants bind TKIs R-HSA-9702509 1.093189e-02 1.961 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.093189e-02 1.961 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.093189e-02 1.961 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.093189e-02 1.961 0 0
midostaurin-resistant FLT3 mutants R-HSA-9702600 1.093189e-02 1.961 0 0
sunitinib-resistant FLT3 mutants R-HSA-9702632 1.093189e-02 1.961 0 0
Nilotinib-resistant KIT mutants R-HSA-9669926 1.093189e-02 1.961 1 1
Sorafenib-resistant KIT mutants R-HSA-9669936 1.093189e-02 1.961 1 1
linifanib-resistant FLT3 mutants R-HSA-9702998 1.093189e-02 1.961 0 0
Regorafenib-resistant KIT mutants R-HSA-9669929 1.093189e-02 1.961 1 1
semaxanib-resistant FLT3 mutants R-HSA-9702577 1.093189e-02 1.961 0 0
pexidartinib-resistant FLT3 mutants R-HSA-9702605 1.093189e-02 1.961 0 0
tamatinib-resistant FLT3 mutants R-HSA-9703009 1.093189e-02 1.961 0 0
tandutinib-resistant FLT3 mutants R-HSA-9702636 1.093189e-02 1.961 0 0
quizartinib-resistant FLT3 mutants R-HSA-9702620 1.093189e-02 1.961 0 0
KW2449-resistant FLT3 mutants R-HSA-9702569 1.093189e-02 1.961 0 0
sorafenib-resistant FLT3 mutants R-HSA-9702624 1.093189e-02 1.961 0 0
gilteritinib-resistant FLT3 mutants R-HSA-9702590 1.093189e-02 1.961 0 0
crenolanib-resistant FLT3 mutants R-HSA-9702581 1.093189e-02 1.961 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.093189e-02 1.961 0 0
Masitinib-resistant KIT mutants R-HSA-9669924 1.093189e-02 1.961 1 1
ponatinib-resistant FLT3 mutants R-HSA-9702614 1.093189e-02 1.961 0 0
lestaurtinib-resistant FLT3 mutants R-HSA-9702596 1.093189e-02 1.961 0 0
Sunitinib-resistant KIT mutants R-HSA-9669934 1.093189e-02 1.961 1 1
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.093189e-02 1.961 0 0
Imatinib-resistant KIT mutants R-HSA-9669917 1.093189e-02 1.961 1 1
Dasatinib-resistant KIT mutants R-HSA-9669914 1.093189e-02 1.961 1 1
Activated NTRK2 signals through FYN R-HSA-9032500 6.713996e-03 2.173 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 6.713996e-03 2.173 0 0
MET receptor recycling R-HSA-8875656 6.713996e-03 2.173 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 6.713996e-03 2.173 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 6.713996e-03 2.173 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 9.243895e-03 2.034 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 9.243895e-03 2.034 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.064424e-02 1.973 0 0
DNA methylation R-HSA-5334118 7.042995e-03 2.152 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 7.603350e-03 2.119 0 0
Downstream signal transduction R-HSA-186763 8.189336e-03 2.087 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 6.363344e-03 2.196 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.028780e-02 1.988 0 0
Interleukin-21 signaling R-HSA-9020958 7.933103e-03 2.101 0 0
Regulation of CDH11 function R-HSA-9762292 9.243895e-03 2.034 0 0
Neutrophil degranulation R-HSA-6798695 6.968068e-03 2.157 0 0
Interleukin-9 signaling R-HSA-8985947 6.713996e-03 2.173 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.079439e-02 1.967 0 0
Semaphorin interactions R-HSA-373755 8.171570e-03 2.088 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 7.042995e-03 2.152 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 7.603350e-03 2.119 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 9.403134e-03 2.027 0 0
Interleukin-18 signaling R-HSA-9012546 6.713996e-03 2.173 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.018302e-02 1.992 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 7.178019e-03 2.144 0 0
Cell-cell junction organization R-HSA-421270 1.074657e-02 1.969 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 8.801207e-03 2.055 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 9.439198e-03 2.025 0 0
ChREBP activates metabolic gene expression R-HSA-163765 1.064424e-02 1.973 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 7.785905e-03 2.109 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.059791e-02 1.975 0 0
Signaling by ALK in cancer R-HSA-9700206 1.059791e-02 1.975 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 8.980033e-03 2.047 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 1.079439e-02 1.967 0 0
Signalling to ERKs R-HSA-187687 1.151198e-02 1.939 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 1.151198e-02 1.939 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 1.151198e-02 1.939 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.188641e-02 1.925 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.213206e-02 1.916 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.221490e-02 1.913 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.225645e-02 1.912 0 0
FLT3 signaling in disease R-HSA-9682385 1.225645e-02 1.912 0 0
Cell-Cell communication R-HSA-1500931 1.260414e-02 1.899 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.302797e-02 1.885 0 0
Cleavage of the damaged purine R-HSA-110331 1.302797e-02 1.885 0 0
MET activates RAS signaling R-HSA-8851805 1.370528e-02 1.863 0 0
Depurination R-HSA-73927 1.382666e-02 1.859 0 0
Interleukin-12 signaling R-HSA-9020591 1.435921e-02 1.843 0 0
Developmental Biology R-HSA-1266738 1.512474e-02 1.820 1 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.536189e-02 1.814 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.550606e-02 1.809 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.550606e-02 1.809 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.638696e-02 1.786 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 1.638696e-02 1.786 0 0
Mitotic Prophase R-HSA-68875 1.685613e-02 1.773 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.729544e-02 1.762 0 0
Cellular responses to stimuli R-HSA-8953897 1.783862e-02 1.749 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 2.174494e-02 1.663 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.225345e-02 1.653 0 0
DCC mediated attractive signaling R-HSA-418885 1.891733e-02 1.723 0 0
Prolonged ERK activation events R-HSA-169893 2.081228e-02 1.682 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 2.120632e-02 1.674 0 0
Nucleosome assembly R-HSA-774815 2.120632e-02 1.674 0 0
Defective pyroptosis R-HSA-9710421 1.919540e-02 1.717 0 0
Signaling by FGFR4 R-HSA-5654743 1.919540e-02 1.717 0 0
Signaling by FGFR3 R-HSA-5654741 2.120632e-02 1.674 0 0
Cell junction organization R-HSA-446728 1.798156e-02 1.745 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 2.278286e-02 1.642 1 1
Innate Immune System R-HSA-168249 2.395765e-02 1.621 0 0
Response to metal ions R-HSA-5660526 2.278286e-02 1.642 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.823157e-02 1.739 0 0
Depyrimidination R-HSA-73928 1.823157e-02 1.739 0 0
Interleukin-12 family signaling R-HSA-447115 2.216581e-02 1.654 0 0
ESR-mediated signaling R-HSA-8939211 2.437593e-02 1.613 0 0
Co-stimulation by CD28 R-HSA-389356 2.443109e-02 1.612 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.443109e-02 1.612 0 0
GPER1 signaling R-HSA-9634597 2.443109e-02 1.612 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.482720e-02 1.605 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.482720e-02 1.605 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 2.524483e-02 1.598 0 0
GAB1 signalosome R-HSA-180292 2.694347e-02 1.570 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.694347e-02 1.570 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.694347e-02 1.570 0 0
FCGR activation R-HSA-2029481 2.771513e-02 1.557 0 0
Assembly of the pre-replicative complex R-HSA-68867 2.771513e-02 1.557 0 0
Meiotic recombination R-HSA-912446 2.790573e-02 1.554 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 2.911932e-02 1.536 0 0
Meiotic synapsis R-HSA-1221632 3.036051e-02 1.518 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 3.036051e-02 1.518 0 0
Parasite infection R-HSA-9664407 3.054594e-02 1.515 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 3.054594e-02 1.515 0 0
Leishmania phagocytosis R-HSA-9664417 3.054594e-02 1.515 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 3.122608e-02 1.505 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 3.162923e-02 1.500 0 0
NTRK3 as a dependence receptor R-HSA-9603505 3.244044e-02 1.489 0 0
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935 3.244044e-02 1.489 1 1
Signaling by extracellular domain mutants of KIT R-HSA-9680187 3.244044e-02 1.489 1 1
Signaling by kinase domain mutants of KIT R-HSA-9669933 3.244044e-02 1.489 1 1
HDACs deacetylate histones R-HSA-3214815 3.292541e-02 1.482 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 3.370606e-02 1.472 0 0
Signalling to RAS R-HSA-167044 3.370606e-02 1.472 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 3.370606e-02 1.472 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 3.370606e-02 1.472 0 0
Signaling by EGFR R-HSA-177929 3.424896e-02 1.465 0 0
Signaling by FGFR1 R-HSA-5654736 3.424896e-02 1.465 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 3.424896e-02 1.465 0 0
Dectin-2 family R-HSA-5621480 3.559980e-02 1.449 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 3.609239e-02 1.443 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 3.609239e-02 1.443 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 3.838289e-02 1.416 0 0
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357 4.301965e-02 1.366 0 0
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046 4.301965e-02 1.366 0 0
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909 4.301965e-02 1.366 0 0
NTF3 activates NTRK3 signaling R-HSA-9034013 4.301965e-02 1.366 0 0
PLC-gamma1 signalling R-HSA-167021 5.348384e-02 1.272 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 5.348384e-02 1.272 0 0
MET interacts with TNS proteins R-HSA-8875513 5.348384e-02 1.272 0 0
Classical Kir channels R-HSA-1296053 5.348384e-02 1.272 0 0
Signalling to STAT3 R-HSA-198745 5.348384e-02 1.272 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 4.362425e-02 1.360 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 5.168164e-02 1.287 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 5.558688e-02 1.255 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 4.894006e-02 1.310 0 0
Signaling by PDGF R-HSA-186797 4.275935e-02 1.369 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 4.894006e-02 1.310 0 0
DNA Double Strand Break Response R-HSA-5693606 5.058250e-02 1.296 0 0
MET activates STAT3 R-HSA-8875791 5.348384e-02 1.272 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 3.981493e-02 1.400 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 5.730569e-02 1.242 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 5.730569e-02 1.242 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 4.437278e-02 1.353 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 5.732455e-02 1.242 0 0
Signaling by EGFR in Cancer R-HSA-1643713 4.894006e-02 1.310 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 5.732455e-02 1.242 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 5.904954e-02 1.229 0 0
Interleukin-20 family signaling R-HSA-8854691 4.105312e-02 1.387 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 5.503562e-02 1.259 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 5.013944e-02 1.300 0 0
DNA Replication Pre-Initiation R-HSA-69002 4.549458e-02 1.342 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 4.894006e-02 1.310 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.981493e-02 1.400 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 4.275935e-02 1.369 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 5.558688e-02 1.255 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 5.168164e-02 1.287 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 5.986946e-02 1.223 0 0
DAP12 signaling R-HSA-2424491 6.022294e-02 1.220 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 6.022294e-02 1.220 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 6.094344e-02 1.215 0 0
Ub-specific processing proteases R-HSA-5689880 6.202835e-02 1.207 0 0
Signaling by FGFR in disease R-HSA-1226099 6.261154e-02 1.203 0 0
G2/M DNA damage checkpoint R-HSA-69473 6.261154e-02 1.203 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 6.312419e-02 1.200 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 6.383425e-02 1.195 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 6.383425e-02 1.195 0 0
Sensory perception of sour taste R-HSA-9729555 6.383425e-02 1.195 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 6.627125e-02 1.179 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 6.920868e-02 1.160 0 0
FGFR1 mutant receptor activation R-HSA-1839124 6.920868e-02 1.160 0 0
Signaling by VEGF R-HSA-194138 6.977896e-02 1.156 0 0
RNA Polymerase I Transcription R-HSA-73864 7.002697e-02 1.155 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 7.121084e-02 1.147 0 0
G2/M Checkpoints R-HSA-69481 7.265774e-02 1.139 0 0
TCF dependent signaling in response to WNT R-HSA-201681 7.347647e-02 1.134 0 0
Signaling by MET R-HSA-6806834 7.387695e-02 1.131 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 7.387695e-02 1.131 0 0
Signaling by FGFR2 R-HSA-5654738 7.387695e-02 1.131 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 7.407210e-02 1.130 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 7.407210e-02 1.130 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 7.407210e-02 1.130 0 0
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403 7.407210e-02 1.130 0 0
NrCAM interactions R-HSA-447038 7.407210e-02 1.130 0 0
RAF activation R-HSA-5673000 7.542750e-02 1.122 0 0
Processing of DNA double-strand break ends R-HSA-5693607 7.583672e-02 1.120 0 0
Amyloid fiber formation R-HSA-977225 7.583672e-02 1.120 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 7.781936e-02 1.109 0 0
GPVI-mediated activation cascade R-HSA-114604 8.181655e-02 1.087 0 0
Meiosis R-HSA-1500620 8.390222e-02 1.076 0 0
Protein-protein interactions at synapses R-HSA-6794362 8.390222e-02 1.076 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 8.419862e-02 1.075 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 8.419862e-02 1.075 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 8.419862e-02 1.075 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 8.419862e-02 1.075 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 8.470072e-02 1.072 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 8.507168e-02 1.070 0 0
mRNA Splicing - Major Pathway R-HSA-72163 8.731161e-02 1.059 0 0
MET promotes cell motility R-HSA-8875878 8.836556e-02 1.054 0 0
Estrogen-dependent gene expression R-HSA-9018519 8.954600e-02 1.048 0 0
Diseases of programmed cell death R-HSA-9645723 9.231841e-02 1.035 0 0
Developmental Cell Lineages R-HSA-9734767 9.366670e-02 1.028 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 9.421501e-02 1.026 0 0
MET Receptor Activation R-HSA-6806942 9.421501e-02 1.026 0 0
Nef and signal transduction R-HSA-164944 9.421501e-02 1.026 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 1.041225e-01 0.982 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.041225e-01 0.982 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.041225e-01 0.982 0 0
IFNG signaling activates MAPKs R-HSA-9732724 1.041225e-01 0.982 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.139221e-01 0.943 0 0
ARMS-mediated activation R-HSA-170984 1.236152e-01 0.908 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 1.332029e-01 0.875 0 0
Signaling by GSK3beta mutants R-HSA-5339716 1.520664e-01 0.818 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.613445e-01 0.792 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 1.613445e-01 0.792 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 1.613445e-01 0.792 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 1.613445e-01 0.792 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 1.613445e-01 0.792 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 1.613445e-01 0.792 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.705217e-01 0.768 0 0
CRMPs in Sema3A signaling R-HSA-399956 1.795990e-01 0.746 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.795990e-01 0.746 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.885775e-01 0.725 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.885775e-01 0.725 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.885775e-01 0.725 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 1.885775e-01 0.725 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.885775e-01 0.725 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.885775e-01 0.725 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.019043e-01 0.992 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.195589e-01 0.922 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 1.041225e-01 0.982 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 1.520664e-01 0.818 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.195589e-01 0.922 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.195589e-01 0.922 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.705217e-01 0.768 0 0
MAP2K and MAPK activation R-HSA-5674135 1.019043e-01 0.992 0 0
Signaling by RAS mutants R-HSA-6802949 1.195589e-01 0.922 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.291641e-01 0.889 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 1.139221e-01 0.943 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.365815e-01 0.865 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.365815e-01 0.865 0 0
mRNA Splicing R-HSA-72172 1.024121e-01 0.990 0 0
DAP12 interactions R-HSA-2172127 1.124073e-01 0.949 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 1.139221e-01 0.943 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.426862e-01 0.846 0 0
Conjugation of benzoate with glycine R-HSA-177135 1.426862e-01 0.846 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.613445e-01 0.792 0 0
Conjugation of salicylate with glycine R-HSA-177128 1.613445e-01 0.792 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.885775e-01 0.725 0 0
Peroxisomal protein import R-HSA-9033241 1.683734e-01 0.774 0 0
Neurexins and neuroligins R-HSA-6794361 1.416402e-01 0.849 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.957462e-02 1.002 0 0
Adrenoceptors R-HSA-390696 1.139221e-01 0.943 0 0
Frs2-mediated activation R-HSA-170968 1.705217e-01 0.768 0 0
p75NTR regulates axonogenesis R-HSA-193697 1.236152e-01 0.908 0 0
Formation of paraxial mesoderm R-HSA-9793380 1.761641e-01 0.754 0 0
VLDL clearance R-HSA-8964046 1.041225e-01 0.982 0 0
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286 1.613445e-01 0.792 0 0
G alpha (s) signalling events R-HSA-418555 1.581530e-01 0.801 0 0
Somitogenesis R-HSA-9824272 1.159689e-01 0.936 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.019043e-01 0.992 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.340928e-01 0.873 0 0
Signaling by FGFR R-HSA-190236 1.195092e-01 0.923 0 0
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661 1.795990e-01 0.746 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.613445e-01 0.792 0 0
Formation of axial mesoderm R-HSA-9796292 1.705217e-01 0.768 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.416402e-01 0.849 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.622965e-01 0.790 0 0
Netrin-1 signaling R-HSA-373752 1.124073e-01 0.949 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.236152e-01 0.908 0 0
Protein methylation R-HSA-8876725 1.885775e-01 0.725 0 0
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290 1.426862e-01 0.846 0 0
Signaling by FGFR4 in disease R-HSA-5655291 1.795990e-01 0.746 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.885775e-01 0.725 0 0
HATs acetylate histones R-HSA-3214847 1.218969e-01 0.914 0 0
RNA Polymerase II Transcription R-HSA-73857 1.849345e-01 0.733 1 0
TCR signaling R-HSA-202403 1.518374e-01 0.819 0 0
Chromosome Maintenance R-HSA-73886 1.865735e-01 0.729 0 0
Co-inhibition by PD-1 R-HSA-389948 9.539438e-02 1.020 0 0
Adaptive Immune System R-HSA-1280218 1.289756e-01 0.889 0 0
Signaling by PTK6 R-HSA-8848021 1.840108e-01 0.735 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.840108e-01 0.735 0 0
Telomere Maintenance R-HSA-157579 1.171392e-01 0.931 0 0
Prolactin receptor signaling R-HSA-1170546 1.795990e-01 0.746 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.291641e-01 0.889 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.311759e-01 0.882 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.139221e-01 0.943 0 0
Platelet activation, signaling and aggregation R-HSA-76002 1.071418e-01 0.970 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.302379e-01 0.885 0 0
Interferon alpha/beta signaling R-HSA-909733 1.702800e-01 0.769 0 0
Deubiquitination R-HSA-5688426 1.871350e-01 0.728 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 1.055652e-01 0.976 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 1.810965e-01 0.742 0 0
DNA Replication R-HSA-69306 1.208140e-01 0.918 0 0
Cellular responses to stress R-HSA-2262752 1.093836e-01 0.961 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 9.846751e-02 1.007 0 0
Cell surface interactions at the vascular wall R-HSA-202733 1.547224e-01 0.810 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 1.019043e-01 0.992 0 0
Base Excision Repair R-HSA-73884 9.665305e-02 1.015 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.267247e-01 0.897 0 0
Leishmania parasite growth and survival R-HSA-9664433 1.623115e-01 0.790 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 1.623115e-01 0.790 0 0
Dissolution of Fibrin Clot R-HSA-75205 1.426862e-01 0.846 0 0
Cellular response to chemical stress R-HSA-9711123 9.967191e-02 1.001 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.124073e-01 0.949 1 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.622965e-01 0.790 0 0
Homology Directed Repair R-HSA-5693538 1.783747e-01 0.749 0 0
Signaling by NOTCH R-HSA-157118 1.599520e-01 0.796 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.865735e-01 0.729 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.268202e-01 0.897 0 0
Gene Silencing by RNA R-HSA-211000 1.441417e-01 0.841 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.919074e-01 0.717 0 0
Cellular response to hypoxia R-HSA-1234174 1.919074e-01 0.717 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.920937e-01 0.716 0 0
Negative regulation of FLT3 R-HSA-9706369 1.974583e-01 0.705 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 1.974583e-01 0.705 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 1.974583e-01 0.705 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 1.974583e-01 0.705 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 1.974583e-01 0.705 0 0
Phase 4 - resting membrane potential R-HSA-5576886 1.974583e-01 0.705 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.974583e-01 0.705 0 0
Differentiation of T cells R-HSA-9945266 1.974583e-01 0.705 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 1.974583e-01 0.705 0 0
Cell Cycle, Mitotic R-HSA-69278 1.993583e-01 0.700 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 2.004502e-01 0.698 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 2.004502e-01 0.698 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 2.004502e-01 0.698 0 0
Generic Transcription Pathway R-HSA-212436 2.047347e-01 0.689 1 0
SHC1 events in ERBB4 signaling R-HSA-1250347 2.062424e-01 0.686 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 2.062424e-01 0.686 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 2.062424e-01 0.686 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 2.078272e-01 0.682 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 2.118295e-01 0.674 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 2.118295e-01 0.674 0 0
HCMV Early Events R-HSA-9609690 2.127339e-01 0.672 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 2.149310e-01 0.668 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 2.149310e-01 0.668 0 0
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265 2.149310e-01 0.668 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.158394e-01 0.666 1 1
Reproduction R-HSA-1474165 2.174122e-01 0.663 0 0
Biosynthesis of Lipoxins (LX) R-HSA-2142700 2.235249e-01 0.651 0 0
Platelet sensitization by LDL R-HSA-432142 2.235249e-01 0.651 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.235249e-01 0.651 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.235249e-01 0.651 0 0
Synaptic adhesion-like molecules R-HSA-8849932 2.235249e-01 0.651 0 0
Tie2 Signaling R-HSA-210993 2.235249e-01 0.651 0 0
Protein ubiquitination R-HSA-8852135 2.319426e-01 0.635 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 2.319426e-01 0.635 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 2.320254e-01 0.634 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.320254e-01 0.634 0 0
Specification of the neural plate border R-HSA-9834899 2.320254e-01 0.634 0 0
Amino Acid conjugation R-HSA-156587 2.320254e-01 0.634 0 0
Conjugation of carboxylic acids R-HSA-159424 2.320254e-01 0.634 0 0
Pyrimidine biosynthesis R-HSA-500753 2.320254e-01 0.634 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 2.320254e-01 0.634 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.320254e-01 0.634 0 0
Rap1 signalling R-HSA-392517 2.320254e-01 0.634 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.337315e-01 0.631 0 0
Leishmania infection R-HSA-9658195 2.377598e-01 0.624 0 0
Parasitic Infection Pathways R-HSA-9824443 2.377598e-01 0.624 0 0
Negative regulation of MET activity R-HSA-6807004 2.404332e-01 0.619 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 2.404332e-01 0.619 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.404332e-01 0.619 0 0
Nephrin family interactions R-HSA-373753 2.404332e-01 0.619 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.404332e-01 0.619 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 2.404332e-01 0.619 0 0
Formation of definitive endoderm R-HSA-9823730 2.404332e-01 0.619 0 0
G alpha (12/13) signalling events R-HSA-416482 2.440698e-01 0.612 0 0
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896 2.487496e-01 0.604 0 0
Basigin interactions R-HSA-210991 2.487496e-01 0.604 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.521698e-01 0.598 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 2.548572e-01 0.594 1 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.569754e-01 0.590 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.569754e-01 0.590 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.569754e-01 0.590 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.569754e-01 0.590 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.569754e-01 0.590 0 0
Disease R-HSA-1643685 2.646620e-01 0.577 1 0
PI-3K cascade:FGFR1 R-HSA-5654689 2.651116e-01 0.577 0 0
Biosynthesis of D-series resolvins R-HSA-9018676 2.651116e-01 0.577 0 0
mTORC1-mediated signalling R-HSA-166208 2.651116e-01 0.577 0 0
LDL clearance R-HSA-8964038 2.651116e-01 0.577 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.698136e-01 0.569 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.724418e-01 0.565 0 0
Signaling by WNT R-HSA-195721 2.727204e-01 0.564 0 0
Termination of O-glycan biosynthesis R-HSA-977068 2.731592e-01 0.564 0 0
Biosynthesis of maresins R-HSA-9018682 2.731592e-01 0.564 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 2.731592e-01 0.564 0 0
XBP1(S) activates chaperone genes R-HSA-381038 2.805490e-01 0.552 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.811192e-01 0.551 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.811192e-01 0.551 0 0
MITF-M-dependent gene expression R-HSA-9856651 2.816710e-01 0.550 0 0
M Phase R-HSA-68886 2.838628e-01 0.547 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.846432e-01 0.546 0 0
Interleukin-1 family signaling R-HSA-446652 2.876181e-01 0.541 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 2.889925e-01 0.539 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 2.889925e-01 0.539 0 0
G protein gated Potassium channels R-HSA-1296059 2.889925e-01 0.539 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 2.889925e-01 0.539 0 0
Long-term potentiation R-HSA-9620244 2.889925e-01 0.539 0 0
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives R-HSA-9027604 2.889925e-01 0.539 0 0
Formation of the nephric duct R-HSA-9830364 2.889925e-01 0.539 0 0
Protein localization R-HSA-9609507 2.905956e-01 0.537 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.905956e-01 0.537 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.935753e-01 0.532 0 0
MET activates PTK2 signaling R-HSA-8874081 2.967801e-01 0.528 0 0
Myogenesis R-HSA-525793 2.967801e-01 0.528 0 0
TRP channels R-HSA-3295583 2.967801e-01 0.528 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 3.007805e-01 0.522 0 0
HCMV Late Events R-HSA-9610379 3.025264e-01 0.519 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 3.044829e-01 0.516 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 3.044829e-01 0.516 0 0
Biosynthesis of DPAn-3 SPMs R-HSA-9025094 3.044829e-01 0.516 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 3.044829e-01 0.516 0 0
Signaling by BMP R-HSA-201451 3.044829e-01 0.516 0 0
Signaling by FGFR3 in disease R-HSA-5655332 3.044829e-01 0.516 0 0
IRE1alpha activates chaperones R-HSA-381070 3.048171e-01 0.516 0 0
Chromatin modifying enzymes R-HSA-3247509 3.058871e-01 0.514 0 0
Eukaryotic Translation Elongation R-HSA-156842 3.088496e-01 0.510 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 3.121017e-01 0.506 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 3.121017e-01 0.506 0 0
Biosynthesis of EPA-derived SPMs R-HSA-9018679 3.196376e-01 0.495 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 3.270913e-01 0.485 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 3.270913e-01 0.485 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 3.344639e-01 0.476 0 0
Biosynthesis of DPA-derived SPMs R-HSA-9018683 3.344639e-01 0.476 0 0
Cargo concentration in the ER R-HSA-5694530 3.344639e-01 0.476 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 3.409140e-01 0.467 0 0
FOXO-mediated transcription R-HSA-9614085 3.409140e-01 0.467 0 0
Inwardly rectifying K+ channels R-HSA-1296065 3.417561e-01 0.466 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 3.417561e-01 0.466 0 0
Signaling by WNT in cancer R-HSA-4791275 3.417561e-01 0.466 0 0
G0 and Early G1 R-HSA-1538133 3.417561e-01 0.466 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 3.417561e-01 0.466 0 0
Chromatin organization R-HSA-4839726 3.429984e-01 0.465 0 0
HCMV Infection R-HSA-9609646 3.454810e-01 0.462 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.489689e-01 0.457 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 3.489689e-01 0.457 0 0
Integrin signaling R-HSA-354192 3.489689e-01 0.457 0 0
Cardiogenesis R-HSA-9733709 3.489689e-01 0.457 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 3.561031e-01 0.448 0 0
Vpu mediated degradation of CD4 R-HSA-180534 3.561031e-01 0.448 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 3.631595e-01 0.440 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.631595e-01 0.440 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 3.631595e-01 0.440 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 3.631595e-01 0.440 0 0
Cell Cycle Checkpoints R-HSA-69620 3.653495e-01 0.437 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 3.701391e-01 0.432 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 3.701391e-01 0.432 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 3.701391e-01 0.432 0 0
Regulation of Apoptosis R-HSA-169911 3.701391e-01 0.432 0 0
SARS-CoV-1-host interactions R-HSA-9692914 3.725093e-01 0.429 0 0
Cellular Senescence R-HSA-2559583 3.742045e-01 0.427 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 3.770425e-01 0.424 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.770425e-01 0.424 0 0
HSF1 activation R-HSA-3371511 3.770425e-01 0.424 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 3.770425e-01 0.424 0 0
RUNX2 regulates bone development R-HSA-8941326 3.770425e-01 0.424 0 0
Stimuli-sensing channels R-HSA-2672351 3.803168e-01 0.420 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.838708e-01 0.416 0 0
Degradation of DVL R-HSA-4641258 3.838708e-01 0.416 0 0
Degradation of AXIN R-HSA-4641257 3.838708e-01 0.416 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 3.838708e-01 0.416 0 0
SLC-mediated transport of organic cations R-HSA-549127 3.838708e-01 0.416 0 0
Hemostasis R-HSA-109582 3.920721e-01 0.407 0 0
FCERI mediated MAPK activation R-HSA-2871796 3.958077e-01 0.403 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 3.973048e-01 0.401 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.973048e-01 0.401 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 3.973048e-01 0.401 0 0
Stabilization of p53 R-HSA-69541 3.973048e-01 0.401 0 0
Plasma lipoprotein clearance R-HSA-8964043 3.973048e-01 0.401 0 0
Pentose phosphate pathway R-HSA-71336 3.973048e-01 0.401 0 0
Generation of second messenger molecules R-HSA-202433 4.039121e-01 0.394 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 4.039121e-01 0.394 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 4.039121e-01 0.394 0 0
Cell Cycle R-HSA-1640170 4.092819e-01 0.388 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 4.104475e-01 0.387 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 4.104475e-01 0.387 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.104475e-01 0.387 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 4.104475e-01 0.387 0 0
PKMTs methylate histone lysines R-HSA-3214841 4.104475e-01 0.387 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 4.111209e-01 0.386 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 4.149198e-01 0.382 0 0
Degradation of CRY and PER proteins R-HSA-9932298 4.169116e-01 0.380 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 4.169116e-01 0.380 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 4.169116e-01 0.380 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 4.169116e-01 0.380 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 4.169116e-01 0.380 0 0
MTOR signalling R-HSA-165159 4.233052e-01 0.373 0 0
Activation of GABAB receptors R-HSA-991365 4.233052e-01 0.373 0 0
GABA B receptor activation R-HSA-977444 4.233052e-01 0.373 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 4.233052e-01 0.373 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 4.296291e-01 0.367 0 0
Gene expression (Transcription) R-HSA-74160 4.320590e-01 0.364 1 0
Proteasome assembly R-HSA-9907900 4.358840e-01 0.361 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 4.358840e-01 0.361 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 4.358840e-01 0.361 0 0
Amine ligand-binding receptors R-HSA-375280 4.358840e-01 0.361 0 0
G1 Phase R-HSA-69236 4.358840e-01 0.361 0 0
Cyclin D associated events in G1 R-HSA-69231 4.358840e-01 0.361 0 0
Cellular response to heat stress R-HSA-3371556 4.374517e-01 0.359 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 4.420707e-01 0.355 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 4.420707e-01 0.355 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 4.420707e-01 0.355 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 4.420707e-01 0.355 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 4.420707e-01 0.355 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 4.420707e-01 0.355 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.420707e-01 0.355 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.481900e-01 0.349 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.481900e-01 0.349 0 0
Apoptotic execution phase R-HSA-75153 4.481900e-01 0.349 0 0
Formation of the cornified envelope R-HSA-6809371 4.485417e-01 0.348 0 0
Host Interactions of HIV factors R-HSA-162909 4.485417e-01 0.348 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.542425e-01 0.343 0 0
Platelet degranulation R-HSA-114608 4.631366e-01 0.334 0 0
Chemokine receptors bind chemokines R-HSA-380108 4.661502e-01 0.331 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 4.661502e-01 0.331 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 4.661502e-01 0.331 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.720068e-01 0.326 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.720068e-01 0.326 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 4.720068e-01 0.326 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 4.777995e-01 0.321 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 4.777995e-01 0.321 0 0
Hedgehog ligand biogenesis R-HSA-5358346 4.777995e-01 0.321 0 0
mRNA 3'-end processing R-HSA-72187 4.835290e-01 0.316 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 4.835290e-01 0.316 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 4.835290e-01 0.316 0 0
Orc1 removal from chromatin R-HSA-68949 4.835290e-01 0.316 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 4.835290e-01 0.316 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.835290e-01 0.316 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 4.881266e-01 0.311 0 0
Amino acids regulate mTORC1 R-HSA-9639288 4.891960e-01 0.311 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.891960e-01 0.311 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.891960e-01 0.311 0 0
Nucleotide biosynthesis R-HSA-8956320 4.891960e-01 0.311 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.891960e-01 0.311 0 0
Smooth Muscle Contraction R-HSA-445355 4.891960e-01 0.311 0 0
Translation initiation complex formation R-HSA-72649 4.948012e-01 0.306 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 4.948012e-01 0.306 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 5.003452e-01 0.301 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 5.003452e-01 0.301 0 0
Paracetamol ADME R-HSA-9753281 5.003452e-01 0.301 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.020794e-01 0.299 0 0
Integration of energy metabolism R-HSA-163685 5.020794e-01 0.299 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 5.058287e-01 0.296 0 0
NRAGE signals death through JNK R-HSA-193648 5.058287e-01 0.296 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 5.058287e-01 0.296 0 0
Nuclear Envelope Breakdown R-HSA-2980766 5.112524e-01 0.291 0 0
PTEN Regulation R-HSA-6807070 5.123833e-01 0.290 0 0
Unfolded Protein Response (UPR) R-HSA-381119 5.123833e-01 0.290 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 5.166168e-01 0.287 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 5.167748e-01 0.287 0 0
Amino acid transport across the plasma membrane R-HSA-352230 5.219228e-01 0.282 0 0
GABA receptor activation R-HSA-977443 5.271708e-01 0.278 0 0
Regulation of PTEN gene transcription R-HSA-8943724 5.271708e-01 0.278 0 0
Glutathione conjugation R-HSA-156590 5.271708e-01 0.278 0 0
Metabolism of polyamines R-HSA-351202 5.271708e-01 0.278 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 5.271708e-01 0.278 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.323615e-01 0.274 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 5.323615e-01 0.274 0 0
Endogenous sterols R-HSA-211976 5.323615e-01 0.274 0 0
FCERI mediated NF-kB activation R-HSA-2871837 5.325691e-01 0.274 0 0
NCAM signaling for neurite out-growth R-HSA-375165 5.374955e-01 0.270 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.374955e-01 0.270 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 5.374955e-01 0.270 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 5.374955e-01 0.270 0 0
Complex I biogenesis R-HSA-6799198 5.425735e-01 0.266 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 5.425735e-01 0.266 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 5.425735e-01 0.266 0 0
CD22 mediated BCR regulation R-HSA-5690714 5.475961e-01 0.262 0 0
Xenobiotics R-HSA-211981 5.475961e-01 0.262 0 0
Gastrulation R-HSA-9758941 5.489530e-01 0.260 0 0
Translation R-HSA-72766 5.524122e-01 0.258 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 5.585897e-01 0.253 0 0
Arachidonate metabolism R-HSA-2142753 5.585897e-01 0.253 0 0
Kidney development R-HSA-9830369 5.623371e-01 0.250 0 0
SLC-mediated transport of amino acids R-HSA-9958863 5.623371e-01 0.250 0 0
Death Receptor Signaling R-HSA-73887 5.649329e-01 0.248 0 0
O-linked glycosylation of mucins R-HSA-913709 5.671439e-01 0.246 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 5.671439e-01 0.246 0 0
Autophagy R-HSA-9612973 5.712109e-01 0.243 0 0
COPII-mediated vesicle transport R-HSA-204005 5.766004e-01 0.239 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 5.766004e-01 0.239 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.766004e-01 0.239 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 5.766004e-01 0.239 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 5.812514e-01 0.236 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.812514e-01 0.236 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.812514e-01 0.236 0 0
Hedgehog 'on' state R-HSA-5632684 5.812514e-01 0.236 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 5.858516e-01 0.232 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 5.858516e-01 0.232 0 0
Apoptosis R-HSA-109581 5.896517e-01 0.229 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 5.904015e-01 0.229 0 0
Switching of origins to a post-replicative state R-HSA-69052 5.904015e-01 0.229 0 0
Ca2+ pathway R-HSA-4086398 5.904015e-01 0.229 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 5.904015e-01 0.229 0 0
Aspirin ADME R-HSA-9749641 5.904015e-01 0.229 0 0
Signaling by ERBB4 R-HSA-1236394 5.949017e-01 0.226 0 0
Signaling by NOTCH4 R-HSA-9013694 5.949017e-01 0.226 0 0
ISG15 antiviral mechanism R-HSA-1169408 5.993527e-01 0.222 0 0
UCH proteinases R-HSA-5689603 6.037551e-01 0.219 0 0
ABC transporter disorders R-HSA-5619084 6.124161e-01 0.213 0 0
PCP/CE pathway R-HSA-4086400 6.124161e-01 0.213 0 0
Sensory processing of sound R-HSA-9659379 6.166757e-01 0.210 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 6.208888e-01 0.207 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 6.250559e-01 0.204 0 0
Neuronal System R-HSA-112316 6.260893e-01 0.203 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 6.291774e-01 0.201 0 0
SARS-CoV-1 Infection R-HSA-9678108 6.303804e-01 0.200 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 6.332538e-01 0.198 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 6.372857e-01 0.196 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 6.412735e-01 0.193 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 6.452178e-01 0.190 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.491189e-01 0.188 0 0
GPCR downstream signalling R-HSA-388396 6.500591e-01 0.187 0 0
Interferon Signaling R-HSA-913531 6.507452e-01 0.187 0 0
Post NMDA receptor activation events R-HSA-438064 6.529773e-01 0.185 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.567935e-01 0.183 0 0
Peptide chain elongation R-HSA-156902 6.567935e-01 0.183 0 0
G2/M Transition R-HSA-69275 6.601358e-01 0.180 0 0
ER-Phagosome pathway R-HSA-1236974 6.605680e-01 0.180 0 0
Neurotransmitter release cycle R-HSA-112310 6.643013e-01 0.178 0 0
Downstream TCR signaling R-HSA-202424 6.643013e-01 0.178 0 0
Mitotic G2-G2/M phases R-HSA-453274 6.653362e-01 0.177 0 0
Ion channel transport R-HSA-983712 6.679125e-01 0.175 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 6.752577e-01 0.171 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.893151e-01 0.162 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 6.893151e-01 0.162 0 0
Mitochondrial translation elongation R-HSA-5389840 6.927339e-01 0.159 0 0
Potassium Channels R-HSA-1296071 6.927339e-01 0.159 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 6.927339e-01 0.159 0 0
Post-translational protein phosphorylation R-HSA-8957275 6.994596e-01 0.155 0 0
Mitochondrial translation initiation R-HSA-5368286 6.994596e-01 0.155 0 0
Hedgehog 'off' state R-HSA-5610787 7.060389e-01 0.151 0 0
ABC-family proteins mediated transport R-HSA-382556 7.060389e-01 0.151 0 0
Interleukin-1 signaling R-HSA-9020702 7.092746e-01 0.149 0 0
Programmed Cell Death R-HSA-5357801 7.093056e-01 0.149 0 0
Keratinization R-HSA-6805567 7.116018e-01 0.148 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 7.124749e-01 0.147 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 7.124749e-01 0.147 0 0
PI Metabolism R-HSA-1483255 7.124749e-01 0.147 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 7.156402e-01 0.145 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.187708e-01 0.143 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 7.250636e-01 0.140 0 0
Muscle contraction R-HSA-397014 7.250636e-01 0.140 0 0
Platelet homeostasis R-HSA-418346 7.279586e-01 0.138 0 0
Metabolism of RNA R-HSA-8953854 7.287734e-01 0.137 0 0
Epigenetic regulation of gene expression R-HSA-212165 7.293690e-01 0.137 0 0
Transmission across Chemical Synapses R-HSA-112315 7.293690e-01 0.137 0 0
Synthesis of DNA R-HSA-69239 7.309543e-01 0.136 0 0
Mitotic Anaphase R-HSA-68882 7.337420e-01 0.134 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 7.339173e-01 0.134 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 7.339173e-01 0.134 0 0
Antigen processing-Cross presentation R-HSA-1236975 7.339173e-01 0.134 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 7.358751e-01 0.133 0 0
Mitochondrial translation termination R-HSA-5419276 7.368478e-01 0.133 0 0
Drug ADME R-HSA-9748784 7.379937e-01 0.132 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.454481e-01 0.128 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.454481e-01 0.128 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 7.537689e-01 0.123 0 0
Signaling by GPCR R-HSA-372790 7.540606e-01 0.123 0 0
HIV Infection R-HSA-162906 7.564199e-01 0.121 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.618192e-01 0.118 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.618192e-01 0.118 0 0
L1CAM interactions R-HSA-373760 7.618192e-01 0.118 0 0
Peptide hormone metabolism R-HSA-2980736 7.644441e-01 0.117 0 0
Phase II - Conjugation of compounds R-HSA-156580 7.792493e-01 0.108 0 0
G1/S Transition R-HSA-69206 7.868101e-01 0.104 0 0
Infectious disease R-HSA-5663205 7.876223e-01 0.104 0 0
DNA Repair R-HSA-73894 7.901532e-01 0.102 0 0
Sensory perception of taste R-HSA-9717189 8.027348e-01 0.095 0 0
Cardiac conduction R-HSA-5576891 8.027348e-01 0.095 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 8.049110e-01 0.094 0 0
Circadian clock R-HSA-9909396 8.049110e-01 0.094 0 0
O-linked glycosylation R-HSA-5173105 8.174761e-01 0.088 0 0
Mitochondrial translation R-HSA-5368287 8.194906e-01 0.086 0 0
Ribosome-associated quality control R-HSA-9948299 8.194906e-01 0.086 0 0
Signaling by Hedgehog R-HSA-5358351 8.194906e-01 0.086 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.254024e-01 0.083 0 0
Macroautophagy R-HSA-1632852 8.254024e-01 0.083 0 0
Clathrin-mediated endocytosis R-HSA-8856828 8.311216e-01 0.080 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 8.311216e-01 0.080 0 0
Bacterial Infection Pathways R-HSA-9824439 8.320009e-01 0.080 0 0
ER to Golgi Anterograde Transport R-HSA-199977 8.384585e-01 0.077 0 0
S Phase R-HSA-69242 8.402426e-01 0.076 0 0
Potential therapeutics for SARS R-HSA-9679191 8.437523e-01 0.074 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.463850e-01 0.072 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.471853e-01 0.072 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 8.505433e-01 0.070 0 0
Fatty acid metabolism R-HSA-8978868 8.517765e-01 0.070 0 0
PPARA activates gene expression R-HSA-1989781 8.521947e-01 0.069 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 8.554433e-01 0.068 0 0
Cellular response to starvation R-HSA-9711097 8.570408e-01 0.067 0 0
Interferon gamma signaling R-HSA-877300 8.586208e-01 0.066 0 0
Signaling by TGFB family members R-HSA-9006936 8.601834e-01 0.065 0 0
Separation of Sister Chromatids R-HSA-2467813 8.662640e-01 0.062 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 8.706513e-01 0.060 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 8.762790e-01 0.057 0 0
Respiratory electron transport R-HSA-611105 8.868145e-01 0.052 0 0
Viral Infection Pathways R-HSA-9824446 8.903338e-01 0.050 0 0
Diseases of glycosylation R-HSA-3781865 8.941262e-01 0.049 0 0
Peptide ligand-binding receptors R-HSA-375276 8.964575e-01 0.047 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 8.987377e-01 0.046 0 0
Extracellular matrix organization R-HSA-1474244 8.999996e-01 0.046 0 0
Mitotic Prometaphase R-HSA-68877 9.042222e-01 0.044 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 9.114077e-01 0.040 0 0
Sphingolipid metabolism R-HSA-428157 9.123894e-01 0.040 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.133604e-01 0.039 0 0
Signaling by ROBO receptors R-HSA-376176 9.143206e-01 0.039 0 0
Neddylation R-HSA-8951664 9.306807e-01 0.031 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.381244e-01 0.028 0 0
rRNA processing R-HSA-72312 9.386905e-01 0.027 0 0
Biological oxidations R-HSA-211859 9.401524e-01 0.027 0 0
Metabolism of nucleotides R-HSA-15869 9.413691e-01 0.026 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.440913e-01 0.025 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.456217e-01 0.024 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.481499e-01 0.023 0 0
G alpha (i) signalling events R-HSA-418594 9.504413e-01 0.022 0 0
SARS-CoV Infections R-HSA-9679506 9.540367e-01 0.020 0 0
G alpha (q) signalling events R-HSA-416476 9.571269e-01 0.019 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.633458e-01 0.016 0 0
Transport of small molecules R-HSA-382551 9.669123e-01 0.015 0 0
Phospholipid metabolism R-HSA-1483257 9.697031e-01 0.013 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 9.713095e-01 0.013 0 0
Membrane Trafficking R-HSA-199991 9.792385e-01 0.009 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.819240e-01 0.008 0 0
GPCR ligand binding R-HSA-500792 9.914319e-01 0.004 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.928280e-01 0.003 0 0
Diseases of metabolism R-HSA-5668914 9.932222e-01 0.003 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.950628e-01 0.002 0 0
Vesicle-mediated transport R-HSA-5653656 9.951122e-01 0.002 0 0
Post-translational protein modification R-HSA-597592 9.962549e-01 0.002 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.992283e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 9.994027e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.994195e-01 0.000 0 0
Sensory Perception R-HSA-9709957 9.999911e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
G2/M DNA damage checkpoint R-HSA-69473 1.110223e-16 15.955 0 0
G2/M Checkpoints R-HSA-69481 1.554312e-15 14.808 0 0
Cell-Cell communication R-HSA-1500931 2.609024e-14 13.584 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.130030e-14 13.384 0 0
Packaging Of Telomere Ends R-HSA-171306 1.147971e-13 12.940 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.147971e-13 12.940 0 0
DNA methylation R-HSA-5334118 2.153833e-13 12.667 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.157474e-13 12.501 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.157474e-13 12.501 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 5.181411e-13 12.286 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 6.833423e-13 12.165 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.163514e-12 11.934 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 1.163514e-12 11.934 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.929679e-12 11.715 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.208012e-12 11.656 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 2.462586e-12 11.609 0 0
Cleavage of the damaged purine R-HSA-110331 2.462586e-12 11.609 0 0
Cell Cycle Checkpoints R-HSA-69620 2.686407e-12 11.571 0 0
Depurination R-HSA-73927 3.125056e-12 11.505 0 0
Meiotic synapsis R-HSA-1221632 3.831380e-12 11.417 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 3.831380e-12 11.417 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 4.952039e-12 11.305 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 4.952039e-12 11.305 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 6.186607e-12 11.209 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 6.186607e-12 11.209 0 0
Cell junction organization R-HSA-446728 9.676371e-12 11.014 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.520496e-12 11.021 0 0
Depyrimidination R-HSA-73928 9.520496e-12 11.021 0 0
Defective pyroptosis R-HSA-9710421 1.173162e-11 10.931 0 0
Adherens junctions interactions R-HSA-418990 1.240341e-11 10.906 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.324751e-11 10.878 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.759193e-11 10.755 0 0
Nucleosome assembly R-HSA-774815 1.759193e-11 10.755 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.141431e-11 10.669 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 3.137857e-11 10.503 0 0
Meiotic recombination R-HSA-912446 5.422807e-11 10.266 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 6.465639e-11 10.189 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 7.253642e-11 10.139 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 8.359913e-11 10.078 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.108525e-11 10.041 0 0
HDACs deacetylate histones R-HSA-3214815 1.076419e-10 9.968 0 0
Cell-cell junction organization R-HSA-421270 1.089080e-10 9.963 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.747861e-10 9.757 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.043818e-10 9.690 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.384042e-10 9.623 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 3.220969e-10 9.492 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 3.220969e-10 9.492 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 4.014851e-10 9.396 0 0
Meiosis R-HSA-1500620 4.530040e-10 9.344 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 5.725884e-10 9.242 0 0
Gene Silencing by RNA R-HSA-211000 6.163468e-10 9.210 0 0
DNA Double Strand Break Response R-HSA-5693606 6.577547e-10 9.182 0 0
Cell Cycle R-HSA-1640170 7.311454e-10 9.136 0 0
Diseases of programmed cell death R-HSA-9645723 7.243233e-10 9.140 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 7.541126e-10 9.123 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 8.668767e-10 9.062 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.856449e-10 9.006 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 9.856449e-10 9.006 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.016121e-09 8.993 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.123763e-09 8.949 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.410152e-09 8.851 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.855479e-09 8.732 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.855479e-09 8.732 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.855479e-09 8.732 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 2.110245e-09 8.676 0 0
M Phase R-HSA-68886 2.153275e-09 8.667 0 0
Mitotic Prophase R-HSA-68875 2.520091e-09 8.599 0 0
Attenuation phase R-HSA-3371568 2.520327e-09 8.599 0 0
RNA Polymerase I Transcription R-HSA-73864 2.684959e-09 8.571 0 0
HATs acetylate histones R-HSA-3214847 2.914549e-09 8.535 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 3.395927e-09 8.469 0 0
Regulation of endogenous retroelements R-HSA-9842860 3.918094e-09 8.407 0 0
Processing of DNA double-strand break ends R-HSA-5693607 3.810977e-09 8.419 0 0
Amyloid fiber formation R-HSA-977225 3.810977e-09 8.419 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 4.270818e-09 8.369 0 0
Cellular responses to stimuli R-HSA-8953897 4.357739e-09 8.361 0 0
DNA Replication Pre-Initiation R-HSA-69002 8.284964e-09 8.082 0 0
Base Excision Repair R-HSA-73884 1.123850e-08 7.949 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.180737e-08 7.928 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.190514e-08 7.924 0 0
EPH-Ephrin signaling R-HSA-2682334 1.519207e-08 7.818 0 0
HSF1-dependent transactivation R-HSA-3371571 1.752805e-08 7.756 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 2.002244e-08 7.698 0 0
Signaling by NOTCH R-HSA-157118 2.105686e-08 7.677 0 0
Ub-specific processing proteases R-HSA-5689880 2.133057e-08 7.671 0 0
Smooth Muscle Contraction R-HSA-445355 2.324260e-08 7.634 0 0
Telomere Maintenance R-HSA-157579 2.699387e-08 7.569 0 0
Cellular response to heat stress R-HSA-3371556 2.717420e-08 7.566 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.184068e-08 7.497 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.245798e-08 7.372 0 0
Signal Transduction R-HSA-162582 4.942730e-08 7.306 1 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 5.513540e-08 7.259 0 0
Activation of HOX genes during differentiation R-HSA-5619507 5.513540e-08 7.259 0 0
Reproduction R-HSA-1474165 6.300851e-08 7.201 0 0
Cell Cycle, Mitotic R-HSA-69278 6.682794e-08 7.175 0 0
Co-inhibition by PD-1 R-HSA-389948 1.055314e-07 6.977 0 0
ESR-mediated signaling R-HSA-8939211 1.164319e-07 6.934 0 0
Activation of BH3-only proteins R-HSA-114452 1.401088e-07 6.854 0 0
Infectious disease R-HSA-5663205 1.275128e-07 6.894 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.251585e-07 6.903 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 1.461818e-07 6.835 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 1.512021e-07 6.820 0 0
Homology Directed Repair R-HSA-5693538 1.978318e-07 6.704 0 0
Muscle contraction R-HSA-397014 2.104431e-07 6.677 0 0
Chromosome Maintenance R-HSA-73886 2.465782e-07 6.608 0 0
Deubiquitination R-HSA-5688426 2.733079e-07 6.563 0 0
TCF dependent signaling in response to WNT R-HSA-201681 2.835762e-07 6.547 0 0
Developmental Biology R-HSA-1266738 2.987604e-07 6.525 1 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 3.043094e-07 6.517 0 0
DNA Replication R-HSA-69306 3.353013e-07 6.475 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 3.517170e-07 6.454 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 3.517170e-07 6.454 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 3.517170e-07 6.454 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 4.197485e-07 6.377 0 0
Cellular responses to stress R-HSA-2262752 4.427970e-07 6.354 0 0
HSF1 activation R-HSA-3371511 4.570471e-07 6.340 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 4.774154e-07 6.321 0 0
Regulation of CDH1 Function R-HSA-9764561 5.523161e-07 6.258 0 0
HCMV Early Events R-HSA-9609690 5.674909e-07 6.246 0 0
Viral Infection Pathways R-HSA-9824446 1.142233e-06 5.942 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.367468e-06 5.864 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.610139e-06 5.793 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.403796e-06 5.619 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.540133e-06 5.595 0 0
Immune System R-HSA-168256 2.795244e-06 5.554 0 0
Signaling by VEGF R-HSA-194138 2.809105e-06 5.551 0 0
HCMV Late Events R-HSA-9610379 2.990695e-06 5.524 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 3.160123e-06 5.500 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 3.329294e-06 5.478 0 0
Protein ubiquitination R-HSA-8852135 3.329294e-06 5.478 0 0
Programmed Cell Death R-HSA-5357801 5.556049e-06 5.255 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 6.152505e-06 5.211 0 0
HCMV Infection R-HSA-9609646 6.682075e-06 5.175 0 0
Signaling by WNT R-HSA-195721 8.012364e-06 5.096 0 0
Cellular Senescence R-HSA-2559583 9.913982e-06 5.004 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.342212e-05 4.872 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.452828e-05 4.838 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.485738e-05 4.828 0 0
Chromatin modifying enzymes R-HSA-3247509 1.833931e-05 4.737 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.139589e-05 4.670 0 0
Apoptosis R-HSA-109581 2.425316e-05 4.615 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.919203e-05 4.535 0 0
Chromatin organization R-HSA-4839726 3.190642e-05 4.496 0 0
Axon guidance R-HSA-422475 3.256583e-05 4.487 0 0
SARS-CoV-1-host interactions R-HSA-9692914 4.079247e-05 4.389 0 0
Disease R-HSA-1643685 5.363478e-05 4.271 1 0
Cell-extracellular matrix interactions R-HSA-446353 5.441835e-05 4.264 0 0
Nervous system development R-HSA-9675108 7.292787e-05 4.137 0 0
Striated Muscle Contraction R-HSA-390522 7.298463e-05 4.137 0 0
L1CAM interactions R-HSA-373760 7.964212e-05 4.099 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 9.604474e-05 4.018 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 9.159386e-05 4.038 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.177257e-04 3.929 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.177257e-04 3.929 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.367092e-04 3.864 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.470691e-04 3.832 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.697892e-04 3.770 0 0
Signaling by Interleukins R-HSA-449147 1.709643e-04 3.767 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.866528e-04 3.729 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.085716e-04 3.681 1 1
Cytokine Signaling in Immune system R-HSA-1280215 2.094747e-04 3.679 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 2.230009e-04 3.652 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 2.283464e-04 3.641 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.382052e-04 3.623 0 0
Centrosome maturation R-HSA-380287 2.710571e-04 3.567 0 0
Interleukin-12 signaling R-HSA-9020591 2.887648e-04 3.539 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.909276e-04 3.536 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.909276e-04 3.536 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.909276e-04 3.536 0 0
Signaling by RAS mutants R-HSA-6802949 2.909276e-04 3.536 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 2.963932e-04 3.528 0 0
Epigenetic regulation of gene expression R-HSA-212165 3.033383e-04 3.518 0 0
CASP4 inflammasome assembly R-HSA-9948001 3.761436e-04 3.425 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 4.344324e-04 3.362 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 4.654016e-04 3.332 0 0
RAF/MAP kinase cascade R-HSA-5673001 4.685760e-04 3.329 1 1
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.501783e-04 3.259 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.125564e-04 3.213 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 5.631709e-04 3.249 1 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 5.787038e-04 3.238 1 0
SARS-CoV-2 Infection R-HSA-9694516 5.774322e-04 3.238 0 0
Interleukin-12 family signaling R-HSA-447115 5.805757e-04 3.236 0 0
DNA Repair R-HSA-73894 7.443747e-04 3.128 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 8.157081e-04 3.088 0 0
Developmental Cell Lineages R-HSA-9734767 8.942011e-04 3.049 0 0
Non-canonical inflammasome activation R-HSA-9686114 9.608945e-04 3.017 0 0
Semaphorin interactions R-HSA-373755 9.914019e-04 3.004 0 0
SARS-CoV-1 Infection R-HSA-9678108 1.116537e-03 2.952 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.120238e-03 2.951 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.165795e-03 2.933 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.277574e-03 2.894 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.336219e-03 2.874 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.458558e-03 2.836 0 0
G2/M Transition R-HSA-69275 1.576443e-03 2.802 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.674222e-03 2.776 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.804308e-03 2.744 0 0
MAPK family signaling cascades R-HSA-5683057 1.852795e-03 2.732 1 0
Signaling by NOTCH4 R-HSA-9013694 1.858354e-03 2.731 0 0
MAP2K and MAPK activation R-HSA-5674135 1.887179e-03 2.724 0 0
Adaptive Immune System R-HSA-1280218 1.920639e-03 2.717 0 0
Ephrin signaling R-HSA-3928664 1.929376e-03 2.715 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.929376e-03 2.715 0 0
Mitotic Prometaphase R-HSA-68877 1.939774e-03 2.712 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.996408e-03 2.700 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.996664e-03 2.700 0 0
Generic Transcription Pathway R-HSA-212436 1.998434e-03 2.699 1 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 2.029565e-03 2.693 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 2.297480e-03 2.639 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.435301e-03 2.613 0 0
Death Receptor Signaling R-HSA-73887 2.435301e-03 2.613 0 0
Signal transduction by L1 R-HSA-445144 2.440141e-03 2.613 0 0
PKR-mediated signaling R-HSA-9833482 2.516244e-03 2.599 0 0
mRNA Splicing R-HSA-72172 2.713457e-03 2.566 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.723944e-03 2.565 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.971913e-03 2.527 1 0
Oncogenic MAPK signaling R-HSA-6802957 3.181838e-03 2.497 0 0
SARS-CoV Infections R-HSA-9679506 3.215237e-03 2.493 0 0
RNA Polymerase II Transcription R-HSA-73857 3.637668e-03 2.439 1 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 4.607662e-03 2.337 0 0
CHL1 interactions R-HSA-447041 5.110336e-03 2.292 0 0
Platelet activation, signaling and aggregation R-HSA-76002 4.136601e-03 2.383 0 0
Parasitic Infection Pathways R-HSA-9824443 4.807395e-03 2.318 0 0
Leishmania infection R-HSA-9658195 4.807395e-03 2.318 0 0
Metabolism of RNA R-HSA-8953854 4.072640e-03 2.390 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 5.110336e-03 2.292 0 0
Gene expression (Transcription) R-HSA-74160 5.144960e-03 2.289 1 0
Uptake and actions of bacterial toxins R-HSA-5339562 3.882693e-03 2.411 0 0
Interaction between L1 and Ankyrins R-HSA-445095 5.280185e-03 2.277 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 6.038024e-03 2.219 0 0
Formation of annular gap junctions R-HSA-196025 6.141270e-03 2.212 0 0
FOXO-mediated transcription R-HSA-9614085 6.396357e-03 2.194 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 6.609019e-03 2.180 0 0
Leishmania phagocytosis R-HSA-9664417 6.609019e-03 2.180 0 0
Parasite infection R-HSA-9664407 6.609019e-03 2.180 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 6.638101e-03 2.178 0 0
Cilium Assembly R-HSA-5617833 6.925013e-03 2.160 0 0
Gap junction degradation R-HSA-190873 7.258740e-03 2.139 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 7.258740e-03 2.139 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 8.460846e-03 2.073 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 9.189100e-03 2.037 0 0
TCR signaling R-HSA-202403 9.719846e-03 2.012 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.022475e-02 1.990 0 0
Drug resistance of KIT mutants R-HSA-9669937 1.044038e-02 1.981 1 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.044038e-02 1.981 0 0
KIT mutants bind TKIs R-HSA-9669921 1.044038e-02 1.981 1 1
PDGFR mutants bind TKIs R-HSA-9674428 1.044038e-02 1.981 0 0
Masitinib-resistant KIT mutants R-HSA-9669924 1.044038e-02 1.981 1 1
Sunitinib-resistant KIT mutants R-HSA-9669934 1.044038e-02 1.981 1 1
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.044038e-02 1.981 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.044038e-02 1.981 0 0
Imatinib-resistant KIT mutants R-HSA-9669917 1.044038e-02 1.981 1 1
Regorafenib-resistant KIT mutants R-HSA-9669929 1.044038e-02 1.981 1 1
Sorafenib-resistant KIT mutants R-HSA-9669936 1.044038e-02 1.981 1 1
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.044038e-02 1.981 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.044038e-02 1.981 0 0
Dasatinib-resistant KIT mutants R-HSA-9669914 1.044038e-02 1.981 1 1
Nilotinib-resistant KIT mutants R-HSA-9669926 1.044038e-02 1.981 1 1
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.045337e-02 1.981 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.089852e-02 1.963 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.111153e-02 1.954 0 0
Membrane Trafficking R-HSA-199991 1.135141e-02 1.945 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.206383e-02 1.919 1 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 1.295890e-02 1.887 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.407873e-02 1.851 0 0
Vesicle-mediated transport R-HSA-5653656 1.425456e-02 1.846 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.483286e-02 1.829 1 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 1.567659e-02 1.805 0 0
Signal regulatory protein family interactions R-HSA-391160 1.567659e-02 1.805 0 0
Protein-protein interactions at synapses R-HSA-6794362 1.721201e-02 1.764 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.734832e-02 1.761 0 0
Protein methylation R-HSA-8876725 1.734832e-02 1.761 0 0
Platelet degranulation R-HSA-114608 1.760977e-02 1.754 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.909221e-02 1.719 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.909221e-02 1.719 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.278984e-02 1.642 0 0
Translation initiation complex formation R-HSA-72649 2.813049e-02 1.551 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 3.048156e-02 1.516 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.090660e-02 1.680 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.675643e-02 1.573 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 2.883662e-02 1.540 0 0
Ion homeostasis R-HSA-5578775 3.048156e-02 1.516 0 0
Rap1 signalling R-HSA-392517 2.675643e-02 1.573 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 2.114914e-02 1.675 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 3.058295e-02 1.515 0 0
Downstream TCR signaling R-HSA-202424 2.107390e-02 1.676 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.699090e-02 1.569 0 0
Uptake and function of anthrax toxins R-HSA-5210891 2.278984e-02 1.642 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.883662e-02 1.540 0 0
NRAGE signals death through JNK R-HSA-193648 3.048156e-02 1.516 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 3.048156e-02 1.516 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 2.090660e-02 1.680 1 1
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 2.759634e-02 1.559 0 0
Nephrin family interactions R-HSA-373753 2.883662e-02 1.540 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.542800e-02 1.595 0 0
Signaling by Hippo R-HSA-2028269 2.278984e-02 1.642 0 0
NTRK3 as a dependence receptor R-HSA-9603505 3.099717e-02 1.509 0 0
Signaling by extracellular domain mutants of KIT R-HSA-9680187 3.099717e-02 1.509 1 1
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935 3.099717e-02 1.509 1 1
PTEN Loss of Function in Cancer R-HSA-5674404 3.099717e-02 1.509 0 0
Signaling by kinase domain mutants of KIT R-HSA-9669933 3.099717e-02 1.509 1 1
Manipulation of host energy metabolism R-HSA-9636667 3.099717e-02 1.509 0 0
Extracellular matrix organization R-HSA-1474244 3.282345e-02 1.484 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 3.293301e-02 1.482 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 3.318311e-02 1.479 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 3.318311e-02 1.479 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.318311e-02 1.479 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.544639e-02 1.450 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 3.776774e-02 1.423 0 0
Syndecan interactions R-HSA-3000170 3.776774e-02 1.423 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.111581e-02 1.386 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.111581e-02 1.386 0 0
NTF3 activates NTRK3 signaling R-HSA-9034013 4.111581e-02 1.386 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.111581e-02 1.386 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.111581e-02 1.386 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.111581e-02 1.386 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.111581e-02 1.386 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.111581e-02 1.386 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.111581e-02 1.386 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.111581e-02 1.386 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.111581e-02 1.386 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.111581e-02 1.386 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 4.111581e-02 1.386 0 0
Long-term potentiation R-HSA-9620244 4.257886e-02 1.371 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 4.257886e-02 1.371 0 0
Sema4D in semaphorin signaling R-HSA-400685 4.257886e-02 1.371 0 0
MET activates PTK2 signaling R-HSA-8874081 4.506582e-02 1.346 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 4.667234e-02 1.331 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.760522e-02 1.322 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.760522e-02 1.322 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 4.795044e-02 1.319 0 0
PIP3 activates AKT signaling R-HSA-1257604 4.959256e-02 1.305 1 1
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 4.971051e-02 1.304 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 5.019568e-02 1.299 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 5.112940e-02 1.291 0 0
Axonal growth stimulation R-HSA-209563 5.112940e-02 1.291 0 0
MET interacts with TNS proteins R-HSA-8875513 5.112940e-02 1.291 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 5.134747e-02 1.289 1 0
DAP12 signaling R-HSA-2424491 5.552456e-02 1.256 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 5.552456e-02 1.256 0 0
Molecules associated with elastic fibres R-HSA-2129379 5.826037e-02 1.235 0 0
NADE modulates death signalling R-HSA-205025 6.103903e-02 1.214 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 6.104207e-02 1.214 0 0
G alpha (12/13) signalling events R-HSA-416482 6.279364e-02 1.202 0 0
Integrin signaling R-HSA-354192 6.386841e-02 1.195 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 6.386841e-02 1.195 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 6.386841e-02 1.195 0 0
Regulation of necroptotic cell death R-HSA-5675482 6.386841e-02 1.195 0 0
Interferon Signaling R-HSA-913531 6.425437e-02 1.192 0 0
Sensory processing of sound R-HSA-9659379 6.453100e-02 1.190 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 6.754520e-02 1.170 1 0
Bacterial Infection Pathways R-HSA-9824439 6.945635e-02 1.158 0 0
RAF activation R-HSA-5673000 6.965018e-02 1.157 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 6.965018e-02 1.157 0 0
eNOS activation R-HSA-203615 6.965018e-02 1.157 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 7.084578e-02 1.150 0 0
Innate Immune System R-HSA-168249 7.449976e-02 1.128 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 8.055070e-02 1.094 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 8.055070e-02 1.094 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 9.965926e-02 1.001 0 0
Regulation of PTEN localization R-HSA-8948747 9.965926e-02 1.001 0 0
Recycling of eIF2:GDP R-HSA-72731 9.965926e-02 1.001 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 9.965926e-02 1.001 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.090650e-01 0.962 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.090650e-01 0.962 0 0
Lipophagy R-HSA-9613354 1.183730e-01 0.927 0 0
ALK mutants bind TKIs R-HSA-9700645 1.183730e-01 0.927 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.275844e-01 0.894 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 1.275844e-01 0.894 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.367000e-01 0.864 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 1.108365e-01 0.955 0 0
Post-translational protein phosphorylation R-HSA-8957275 1.079827e-01 0.967 0 0
Regulation of PTEN stability and activity R-HSA-8948751 1.350737e-01 0.869 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.183730e-01 0.927 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.168577e-01 0.932 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 1.090650e-01 0.962 0 0
Regulation of CDH11 function R-HSA-9762292 1.275844e-01 0.894 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.367000e-01 0.864 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.353840e-01 0.868 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.275844e-01 0.894 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 7.559611e-02 1.122 0 0
PTEN Regulation R-HSA-6807070 8.307900e-02 1.081 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.074763e-01 0.969 0 0
Post NMDA receptor activation events R-HSA-438064 8.113746e-02 1.091 0 0
PTK6 Expression R-HSA-8849473 9.965926e-02 1.001 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 1.090650e-01 0.962 0 0
Calcineurin activates NFAT R-HSA-2025928 1.183730e-01 0.927 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 8.055070e-02 1.094 0 0
DAG and IP3 signaling R-HSA-1489509 1.074763e-01 0.969 0 0
Cam-PDE 1 activation R-HSA-111957 8.055070e-02 1.094 0 0
p75NTR regulates axonogenesis R-HSA-193697 1.183730e-01 0.927 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.367000e-01 0.864 0 0
vRNP Assembly R-HSA-192905 1.367000e-01 0.864 0 0
NF-kB is activated and signals survival R-HSA-209560 1.457210e-01 0.836 0 0
MET promotes cell motility R-HSA-8875878 8.169701e-02 1.088 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.111947e-02 1.040 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 9.728226e-02 1.012 1 1
GP1b-IX-V activation signalling R-HSA-430116 1.183730e-01 0.927 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 1.280299e-01 0.893 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.169701e-02 1.088 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 1.090650e-01 0.962 0 0
ARMS-mediated activation R-HSA-170984 1.183730e-01 0.927 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.275844e-01 0.894 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.457210e-01 0.836 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 8.794394e-02 1.056 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.330146e-01 0.876 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.330146e-01 0.876 0 0
GPVI-mediated activation cascade R-HSA-114604 7.559611e-02 1.122 0 0
Clathrin-mediated endocytosis R-HSA-8856828 9.067277e-02 1.043 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.494092e-01 0.826 0 0
Degradation of CDH1 R-HSA-9766229 1.210777e-01 0.917 0 0
Generation of second messenger molecules R-HSA-202433 8.794394e-02 1.056 0 0
Protein folding R-HSA-391251 9.313034e-02 1.031 0 0
Alpha-defensins R-HSA-1462054 1.090650e-01 0.962 0 0
Sodium/Calcium exchangers R-HSA-425561 1.457210e-01 0.836 0 0
Recycling pathway of L1 R-HSA-437239 1.142241e-01 0.942 0 0
Neurexins and neuroligins R-HSA-6794361 1.315408e-01 0.881 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 8.055070e-02 1.094 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 8.055070e-02 1.094 0 0
Nef and signal transduction R-HSA-164944 9.015485e-02 1.045 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 1.183730e-01 0.927 0 0
Gap junction trafficking R-HSA-190828 1.041444e-01 0.982 0 0
DAP12 interactions R-HSA-2172127 1.041444e-01 0.982 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.153416e-01 0.938 0 0
Elastic fibre formation R-HSA-1566948 8.169701e-02 1.088 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.183730e-01 0.927 0 0
Gap junction trafficking and regulation R-HSA-157858 1.210777e-01 0.917 0 0
HIV Infection R-HSA-162906 1.199437e-01 0.921 0 0
Inositol phosphate metabolism R-HSA-1483249 1.425786e-01 0.846 0 0
PECAM1 interactions R-HSA-210990 1.367000e-01 0.864 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.169701e-02 1.088 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.407231e-01 0.852 0 0
Hemostasis R-HSA-109582 1.414302e-01 0.849 0 0
Glycolysis R-HSA-70171 1.123863e-01 0.949 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.146137e-01 0.941 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.494092e-01 0.826 0 0
RSV-host interactions R-HSA-9833110 1.236879e-01 0.908 0 0
Potential therapeutics for SARS R-HSA-9679191 1.018415e-01 0.992 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.183730e-01 0.927 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 1.051444e-01 0.978 0 0
Metabolism of proteins R-HSA-392499 1.420049e-01 0.848 0 0
Post-translational protein modification R-HSA-597592 1.127379e-01 0.948 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 8.905441e-02 1.050 0 0
Gluconeogenesis R-HSA-70263 1.176382e-01 0.929 0 0
Azathioprine ADME R-HSA-9748787 1.245420e-01 0.905 0 0
Dissolution of Fibrin Clot R-HSA-75205 1.367000e-01 0.864 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 1.008418e-01 0.996 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.041444e-01 0.982 1 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 1.058069e-01 0.975 0 0
Apoptotic execution phase R-HSA-75153 1.108365e-01 0.955 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 1.498983e-01 0.824 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.546483e-01 0.811 0 0
Scavenging by Class F Receptors R-HSA-3000484 1.546483e-01 0.811 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.546483e-01 0.811 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 1.546483e-01 0.811 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.546483e-01 0.811 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 1.546483e-01 0.811 0 0
Pervasive developmental disorders R-HSA-9005895 1.546483e-01 0.811 0 0
Disorders of Nervous System Development R-HSA-9697154 1.546483e-01 0.811 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.546483e-01 0.811 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.573366e-01 0.803 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.573366e-01 0.803 0 0
Glucose metabolism R-HSA-70326 1.598413e-01 0.796 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.603527e-01 0.795 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.634828e-01 0.787 0 0
Frs2-mediated activation R-HSA-170968 1.634828e-01 0.787 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 1.634828e-01 0.787 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.634828e-01 0.787 0 0
PLC beta mediated events R-HSA-112043 1.640331e-01 0.785 0 0
Formation of paraxial mesoderm R-HSA-9793380 1.640331e-01 0.785 0 0
NCAM signaling for neurite out-growth R-HSA-375165 1.677285e-01 0.775 0 0
Regulation of KIT signaling R-HSA-1433559 1.722255e-01 0.764 1 1
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.722255e-01 0.764 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.722255e-01 0.764 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 1.722255e-01 0.764 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.751183e-01 0.757 1 1
Host Interactions of HIV factors R-HSA-162909 1.777038e-01 0.750 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.808774e-01 0.743 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.808774e-01 0.743 0 0
DCC mediated attractive signaling R-HSA-418885 1.808774e-01 0.743 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.808774e-01 0.743 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 1.808774e-01 0.743 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.808774e-01 0.743 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.808774e-01 0.743 0 0
p75NTR signals via NF-kB R-HSA-193639 1.808774e-01 0.743 0 0
Other semaphorin interactions R-HSA-416700 1.808774e-01 0.743 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 1.855229e-01 0.732 0 0
G-protein mediated events R-HSA-112040 1.864067e-01 0.730 0 0
Prolonged ERK activation events R-HSA-169893 1.894394e-01 0.723 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 1.894394e-01 0.723 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.894394e-01 0.723 0 0
Regulated Necrosis R-HSA-5218859 1.901779e-01 0.721 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 1.979125e-01 0.704 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 1.979125e-01 0.704 0 0
Fibronectin matrix formation R-HSA-1566977 1.979125e-01 0.704 0 0
Disorders of Developmental Biology R-HSA-9675151 1.979125e-01 0.704 0 0
Cardiac conduction R-HSA-5576891 2.014229e-01 0.696 0 0
ECM proteoglycans R-HSA-3000178 2.015510e-01 0.696 0 0
Metabolism of cofactors R-HSA-8978934 2.015510e-01 0.696 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.062975e-01 0.686 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.062975e-01 0.686 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.091767e-01 0.679 0 0
Synaptic adhesion-like molecules R-HSA-8849932 2.145953e-01 0.668 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.145953e-01 0.668 0 0
PKA activation R-HSA-163615 2.145953e-01 0.668 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.145953e-01 0.668 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.145953e-01 0.668 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.168317e-01 0.664 0 0
UCH proteinases R-HSA-5689603 2.206689e-01 0.656 0 0
The NLRP3 inflammasome R-HSA-844456 2.228069e-01 0.652 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.258369e-01 0.646 0 0
Integrin cell surface interactions R-HSA-216083 2.283597e-01 0.641 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 2.309331e-01 0.637 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.309331e-01 0.637 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.309331e-01 0.637 0 0
Signaling by MET R-HSA-6806834 2.360690e-01 0.627 0 0
Mitotic Anaphase R-HSA-68882 2.366482e-01 0.626 0 0
Late Phase of HIV Life Cycle R-HSA-162599 2.368689e-01 0.625 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.388946e-01 0.622 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.389749e-01 0.622 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.389749e-01 0.622 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 2.389749e-01 0.622 0 0
Basigin interactions R-HSA-210991 2.389749e-01 0.622 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.437928e-01 0.613 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.469331e-01 0.607 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.469331e-01 0.607 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.469331e-01 0.607 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.469331e-01 0.607 0 0
Signaling by KIT in disease R-HSA-9669938 2.548085e-01 0.594 1 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 2.548085e-01 0.594 1 1
Regulation of IFNA/IFNB signaling R-HSA-912694 2.548085e-01 0.594 0 0
Notch-HLH transcription pathway R-HSA-350054 2.548085e-01 0.594 0 0
mTORC1-mediated signalling R-HSA-166208 2.548085e-01 0.594 0 0
Neuronal System R-HSA-112316 2.553320e-01 0.593 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.592682e-01 0.586 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.592682e-01 0.586 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 2.592682e-01 0.586 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 2.626021e-01 0.581 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 2.626021e-01 0.581 0 0
Formation of the ureteric bud R-HSA-9830674 2.626021e-01 0.581 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.626021e-01 0.581 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 2.626021e-01 0.581 0 0
Deadenylation of mRNA R-HSA-429947 2.703146e-01 0.568 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.703146e-01 0.568 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.703146e-01 0.568 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 2.703146e-01 0.568 0 0
Mitochondrial RNA degradation R-HSA-9836573 2.703146e-01 0.568 0 0
Neurodegenerative Diseases R-HSA-8863678 2.703146e-01 0.568 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.703146e-01 0.568 0 0
Selective autophagy R-HSA-9663891 2.708849e-01 0.567 0 0
Autophagy R-HSA-9612973 2.761257e-01 0.559 0 0
Laminin interactions R-HSA-3000157 2.779470e-01 0.556 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 2.779470e-01 0.556 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 2.779470e-01 0.556 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 2.779470e-01 0.556 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 2.779470e-01 0.556 0 0
HIV Life Cycle R-HSA-162587 2.789588e-01 0.554 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.854999e-01 0.544 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.854999e-01 0.544 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 2.854999e-01 0.544 0 0
Signaling by TGFB family members R-HSA-9006936 2.874743e-01 0.541 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 2.929744e-01 0.533 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 2.929744e-01 0.533 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 2.929744e-01 0.533 0 0
Cristae formation R-HSA-8949613 2.929744e-01 0.533 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.929744e-01 0.533 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 2.940945e-01 0.532 0 0
Mitochondrial protein degradation R-HSA-9837999 2.979551e-01 0.526 0 0
Separation of Sister Chromatids R-HSA-2467813 2.988599e-01 0.525 0 0
HIV elongation arrest and recovery R-HSA-167287 3.003711e-01 0.522 0 0
Pausing and recovery of HIV elongation R-HSA-167290 3.003711e-01 0.522 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 3.003711e-01 0.522 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 3.003711e-01 0.522 0 0
Inflammasomes R-HSA-622312 3.003711e-01 0.522 0 0
Late endosomal microautophagy R-HSA-9615710 3.076908e-01 0.512 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.076908e-01 0.512 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.076908e-01 0.512 0 0
DARPP-32 events R-HSA-180024 3.076908e-01 0.512 0 0
Platelet calcium homeostasis R-HSA-418360 3.076908e-01 0.512 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 3.133624e-01 0.504 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 3.149345e-01 0.502 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.149345e-01 0.502 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 3.149345e-01 0.502 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.149345e-01 0.502 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 3.149345e-01 0.502 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.188398e-01 0.496 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.221027e-01 0.492 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.221027e-01 0.492 0 0
Downstream signal transduction R-HSA-186763 3.221027e-01 0.492 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 3.221027e-01 0.492 0 0
Budding and maturation of HIV virion R-HSA-162588 3.221027e-01 0.492 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 3.221027e-01 0.492 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.221027e-01 0.492 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 3.221027e-01 0.492 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.248714e-01 0.488 0 0
Hedgehog 'off' state R-HSA-5610787 3.248714e-01 0.488 0 0
ABC-family proteins mediated transport R-HSA-382556 3.248714e-01 0.488 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 3.274125e-01 0.485 0 0
Leishmania parasite growth and survival R-HSA-9664433 3.274125e-01 0.485 0 0
Interleukin-1 signaling R-HSA-9020702 3.286971e-01 0.483 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 3.291965e-01 0.483 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 3.291965e-01 0.483 0 0
G0 and Early G1 R-HSA-1538133 3.291965e-01 0.483 0 0
PI Metabolism R-HSA-1483255 3.325171e-01 0.478 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 3.362164e-01 0.473 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.362164e-01 0.473 0 0
G-protein beta:gamma signalling R-HSA-397795 3.362164e-01 0.473 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.362164e-01 0.473 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.362164e-01 0.473 0 0
Opioid Signalling R-HSA-111885 3.401385e-01 0.468 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.431633e-01 0.464 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.431633e-01 0.464 0 0
Vpu mediated degradation of CD4 R-HSA-180534 3.431633e-01 0.464 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.431633e-01 0.464 0 0
Nuclear import of Rev protein R-HSA-180746 3.500379e-01 0.456 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 3.500379e-01 0.456 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 3.500379e-01 0.456 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.552993e-01 0.449 0 0
Signaling by ALK in cancer R-HSA-9700206 3.552993e-01 0.449 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.568410e-01 0.448 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 3.568410e-01 0.448 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 3.568410e-01 0.448 0 0
Signalling to ERKs R-HSA-187687 3.568410e-01 0.448 0 0
Regulation of Apoptosis R-HSA-169911 3.568410e-01 0.448 0 0
PERK regulates gene expression R-HSA-381042 3.568410e-01 0.448 0 0
CaM pathway R-HSA-111997 3.635733e-01 0.439 0 0
Calmodulin induced events R-HSA-111933 3.635733e-01 0.439 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 3.635733e-01 0.439 0 0
FLT3 signaling in disease R-HSA-9682385 3.635733e-01 0.439 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 3.635733e-01 0.439 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 3.701880e-01 0.432 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 3.702355e-01 0.432 0 0
Degradation of DVL R-HSA-4641258 3.702355e-01 0.432 0 0
Degradation of AXIN R-HSA-4641257 3.702355e-01 0.432 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 3.702355e-01 0.432 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.702355e-01 0.432 0 0
Ovarian tumor domain proteases R-HSA-5689896 3.702355e-01 0.432 0 0
FCERI mediated MAPK activation R-HSA-2871796 3.740749e-01 0.427 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.768284e-01 0.424 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.833527e-01 0.416 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.833527e-01 0.416 0 0
RAS processing R-HSA-9648002 3.833527e-01 0.416 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.833527e-01 0.416 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 3.833527e-01 0.416 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.833527e-01 0.416 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 3.833527e-01 0.416 0 0
Stabilization of p53 R-HSA-69541 3.833527e-01 0.416 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.898091e-01 0.409 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.898091e-01 0.409 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.898091e-01 0.409 0 0
HIV Transcription Elongation R-HSA-167169 3.898091e-01 0.409 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.898091e-01 0.409 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.898091e-01 0.409 0 0
Diseases of Immune System R-HSA-5260271 3.898091e-01 0.409 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 3.898091e-01 0.409 0 0
Aggrephagy R-HSA-9646399 3.898091e-01 0.409 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 3.898091e-01 0.409 0 0
Glycogen metabolism R-HSA-8982491 3.898091e-01 0.409 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 3.926281e-01 0.406 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 3.961982e-01 0.402 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 3.961982e-01 0.402 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 3.961982e-01 0.402 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 3.961982e-01 0.402 0 0
Mitochondrial biogenesis R-HSA-1592230 3.999810e-01 0.398 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 4.025209e-01 0.395 0 0
Degradation of CRY and PER proteins R-HSA-9932298 4.025209e-01 0.395 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 4.025209e-01 0.395 0 0
Scavenging by Class A Receptors R-HSA-3000480 4.025209e-01 0.395 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 4.025209e-01 0.395 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 4.025209e-01 0.395 0 0
Negative regulation of MAPK pathway R-HSA-5675221 4.025209e-01 0.395 0 0
Ca-dependent events R-HSA-111996 4.087778e-01 0.389 0 0
MTOR signalling R-HSA-165159 4.087778e-01 0.389 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 4.087778e-01 0.389 0 0
Infection with Enterobacteria R-HSA-9640148 4.124711e-01 0.385 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.145613e-01 0.382 0 0
Signaling by SCF-KIT R-HSA-1433557 4.149695e-01 0.382 1 1
Defensins R-HSA-1461973 4.149695e-01 0.382 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 4.149695e-01 0.382 0 0
Response of Mtb to phagocytosis R-HSA-9637690 4.149695e-01 0.382 0 0
Netrin-1 signaling R-HSA-373752 4.210967e-01 0.376 0 0
Proteasome assembly R-HSA-9907900 4.210967e-01 0.376 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 4.210967e-01 0.376 0 0
Methylation R-HSA-156581 4.210967e-01 0.376 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 4.271602e-01 0.369 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.271602e-01 0.369 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 4.271602e-01 0.369 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 4.271602e-01 0.369 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 4.271602e-01 0.369 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 4.271602e-01 0.369 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 4.271602e-01 0.369 0 0
Somitogenesis R-HSA-9824272 4.271602e-01 0.369 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.331605e-01 0.363 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.331605e-01 0.363 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 4.331605e-01 0.363 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 4.331605e-01 0.363 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 4.331605e-01 0.363 0 0
Regulation of pyruvate metabolism R-HSA-9861718 4.331605e-01 0.363 0 0
Regulation of TNFR1 signaling R-HSA-5357905 4.331605e-01 0.363 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.390983e-01 0.357 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 4.390983e-01 0.357 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 4.401813e-01 0.356 0 0
GPER1 signaling R-HSA-9634597 4.449743e-01 0.352 0 0
Metal ion SLC transporters R-HSA-425410 4.449743e-01 0.352 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 4.507891e-01 0.346 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 4.507891e-01 0.346 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 4.507891e-01 0.346 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.565433e-01 0.341 0 0
Circadian clock R-HSA-9909396 4.606757e-01 0.337 0 0
Complex IV assembly R-HSA-9864848 4.622376e-01 0.335 0 0
The phototransduction cascade R-HSA-2514856 4.622376e-01 0.335 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 4.622376e-01 0.335 0 0
Hedgehog ligand biogenesis R-HSA-5358346 4.622376e-01 0.335 0 0
mRNA 3'-end processing R-HSA-72187 4.678726e-01 0.330 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.678726e-01 0.330 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 4.678726e-01 0.330 0 0
Orc1 removal from chromatin R-HSA-68949 4.678726e-01 0.330 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 4.678726e-01 0.330 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.678726e-01 0.330 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.734489e-01 0.325 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.734489e-01 0.325 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.734489e-01 0.325 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.734489e-01 0.325 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 4.778486e-01 0.321 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 4.789671e-01 0.320 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 4.844278e-01 0.315 0 0
Signaling by NOTCH3 R-HSA-9012852 4.844278e-01 0.315 0 0
Signaling by Hedgehog R-HSA-5358351 4.846247e-01 0.315 0 0
Transmission across Chemical Synapses R-HSA-112315 4.861051e-01 0.313 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 4.898316e-01 0.310 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 4.898316e-01 0.310 0 0
TNF signaling R-HSA-75893 4.898316e-01 0.310 0 0
rRNA processing R-HSA-72312 4.940024e-01 0.306 0 0
Macroautophagy R-HSA-1632852 4.946870e-01 0.306 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.057075e-01 0.296 0 0
Metabolism of non-coding RNA R-HSA-194441 5.057075e-01 0.296 0 0
snRNP Assembly R-HSA-191859 5.057075e-01 0.296 0 0
Regulation of beta-cell development R-HSA-186712 5.057075e-01 0.296 0 0
FCERI mediated NF-kB activation R-HSA-2871837 5.079097e-01 0.294 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 5.108895e-01 0.292 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 5.108895e-01 0.292 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 5.108895e-01 0.292 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 5.108895e-01 0.292 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 5.108895e-01 0.292 0 0
Signaling by ERBB2 R-HSA-1227986 5.108895e-01 0.292 0 0
Metabolism of polyamines R-HSA-351202 5.108895e-01 0.292 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 5.144367e-01 0.289 0 0
Viral Messenger RNA Synthesis R-HSA-168325 5.160176e-01 0.287 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.160176e-01 0.287 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 5.160176e-01 0.287 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.176789e-01 0.286 0 0
Signaling by NTRKs R-HSA-166520 5.209068e-01 0.283 0 0
Signaling by PDGF R-HSA-186797 5.210922e-01 0.283 0 0
tRNA processing in the nucleus R-HSA-6784531 5.210922e-01 0.283 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 5.210922e-01 0.283 0 0
Mitochondrial protein import R-HSA-1268020 5.210922e-01 0.283 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.210922e-01 0.283 0 0
Gastrulation R-HSA-9758941 5.241203e-01 0.281 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 5.261139e-01 0.279 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 5.261139e-01 0.279 0 0
Signaling by PTK6 R-HSA-8848021 5.261139e-01 0.279 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 5.261139e-01 0.279 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 5.273195e-01 0.278 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.310832e-01 0.275 0 0
Ion transport by P-type ATPases R-HSA-936837 5.310832e-01 0.275 0 0
Interleukin-1 family signaling R-HSA-446652 5.336743e-01 0.273 0 0
Cellular response to hypoxia R-HSA-1234174 5.360008e-01 0.271 0 0
Protein localization R-HSA-9609507 5.368300e-01 0.270 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 5.430975e-01 0.265 0 0
Kidney development R-HSA-9830369 5.456826e-01 0.263 0 0
Transcription of the HIV genome R-HSA-167172 5.504479e-01 0.259 0 0
COPII-mediated vesicle transport R-HSA-204005 5.598300e-01 0.252 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 5.598300e-01 0.252 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 5.598300e-01 0.252 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.598300e-01 0.252 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.644478e-01 0.248 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.644478e-01 0.248 0 0
Hedgehog 'on' state R-HSA-5632684 5.644478e-01 0.248 0 0
Neutrophil degranulation R-HSA-6798695 5.650940e-01 0.248 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 5.690174e-01 0.245 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 5.690174e-01 0.245 0 0
Ca2+ pathway R-HSA-4086398 5.735394e-01 0.241 0 0
Switching of origins to a post-replicative state R-HSA-69052 5.735394e-01 0.241 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 5.780142e-01 0.238 0 0
Signaling by NOTCH1 R-HSA-1980143 5.868242e-01 0.231 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 5.954514e-01 0.225 0 0
ABC transporter disorders R-HSA-5619084 5.954514e-01 0.225 0 0
PCP/CE pathway R-HSA-4086400 5.954514e-01 0.225 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 6.038995e-01 0.219 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 6.038995e-01 0.219 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 6.080576e-01 0.216 0 0
Cytoprotection by HMOX1 R-HSA-9707564 6.162439e-01 0.210 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 6.162439e-01 0.210 0 0
Influenza Infection R-HSA-168255 6.164289e-01 0.210 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.202731e-01 0.207 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 6.242603e-01 0.205 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 6.282058e-01 0.202 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.321102e-01 0.199 0 0
Chaperonin-mediated protein folding R-HSA-390466 6.359738e-01 0.197 0 0
Pyruvate metabolism R-HSA-70268 6.359738e-01 0.197 0 0
ER-Phagosome pathway R-HSA-1236974 6.435803e-01 0.191 0 0
Neurotransmitter release cycle R-HSA-112310 6.473242e-01 0.189 0 0
Toll-like Receptor Cascades R-HSA-168898 6.483101e-01 0.188 0 0
FCGR activation R-HSA-2029481 6.619125e-01 0.179 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.724587e-01 0.172 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 6.724587e-01 0.172 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 6.756687e-01 0.170 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.759009e-01 0.170 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 6.826778e-01 0.166 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 6.826778e-01 0.166 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 6.826778e-01 0.166 0 0
Regulation of insulin secretion R-HSA-422356 6.826778e-01 0.166 0 0
Translation R-HSA-72766 6.976886e-01 0.156 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 7.021747e-01 0.154 0 0
Nucleotide Excision Repair R-HSA-5696398 7.084053e-01 0.150 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 7.084053e-01 0.150 0 0
Platelet homeostasis R-HSA-418346 7.114718e-01 0.148 0 0
Synthesis of DNA R-HSA-69239 7.145063e-01 0.146 0 0
Drug ADME R-HSA-9748784 7.145388e-01 0.146 0 0
Antigen processing-Cross presentation R-HSA-1236975 7.175090e-01 0.144 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 7.175090e-01 0.144 0 0
Stimuli-sensing channels R-HSA-2672351 7.175090e-01 0.144 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 7.204803e-01 0.142 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.234206e-01 0.141 0 0
MyD88-independent TLR4 cascade R-HSA-166166 7.234206e-01 0.141 0 0
Antimicrobial peptides R-HSA-6803157 7.263301e-01 0.139 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 7.320582e-01 0.135 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 7.325579e-01 0.135 0 0
GPCR downstream signalling R-HSA-388396 7.333728e-01 0.135 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 7.375658e-01 0.132 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 7.385604e-01 0.132 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 7.404276e-01 0.131 0 0
Interferon alpha/beta signaling R-HSA-909733 7.431592e-01 0.129 0 0
Rab regulation of trafficking R-HSA-9007101 7.485371e-01 0.126 0 0
Cell surface interactions at the vascular wall R-HSA-202733 7.533084e-01 0.123 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 7.538030e-01 0.123 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 7.538030e-01 0.123 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 7.538030e-01 0.123 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 7.589592e-01 0.120 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 7.589592e-01 0.120 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.614969e-01 0.118 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.614969e-01 0.118 0 0
G1/S Transition R-HSA-69206 7.713850e-01 0.113 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.718436e-01 0.112 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 7.785326e-01 0.109 0 0
Integration of energy metabolism R-HSA-163685 8.007914e-01 0.096 0 0
Ribosome-associated quality control R-HSA-9948299 8.049687e-01 0.094 0 0
Cellular response to chemical stress R-HSA-9711123 8.068703e-01 0.093 0 0
Signaling by GPCR R-HSA-372790 8.196582e-01 0.086 0 0
Visual phototransduction R-HSA-2187338 8.245845e-01 0.084 0 0
S Phase R-HSA-69242 8.264348e-01 0.083 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 8.264348e-01 0.083 0 0
G alpha (i) signalling events R-HSA-418594 8.292759e-01 0.081 0 0
MITF-M-dependent gene expression R-HSA-9856651 8.300773e-01 0.081 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 8.318699e-01 0.080 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.336438e-01 0.079 0 0
Cellular response to starvation R-HSA-9711097 8.439030e-01 0.074 0 0
Phospholipid metabolism R-HSA-1483257 8.448679e-01 0.073 0 0
Regulation of TP53 Activity R-HSA-5633007 8.471809e-01 0.072 0 0
SLC transporter disorders R-HSA-5619102 8.581241e-01 0.066 0 0
tRNA processing R-HSA-72306 8.640238e-01 0.063 0 0
G alpha (s) signalling events R-HSA-418555 8.654603e-01 0.063 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 8.710566e-01 0.060 0 0
Respiratory electron transport R-HSA-611105 8.751015e-01 0.058 0 0
Peptide ligand-binding receptors R-HSA-375276 8.852816e-01 0.053 0 0
Ion channel transport R-HSA-983712 8.888826e-01 0.051 0 0
Signaling by ROBO receptors R-HSA-376176 9.042568e-01 0.044 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.131933e-01 0.039 0 0
Neddylation R-HSA-8951664 9.217932e-01 0.035 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.354481e-01 0.029 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.481743e-01 0.023 0 0
G alpha (q) signalling events R-HSA-416476 9.505681e-01 0.022 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.574380e-01 0.019 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.592202e-01 0.018 0 0
Biological oxidations R-HSA-211859 9.792479e-01 0.009 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.863505e-01 0.006 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.878752e-01 0.005 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.882609e-01 0.005 0 0
GPCR ligand binding R-HSA-500792 9.985356e-01 0.001 0 0
Transport of small molecules R-HSA-382551 9.985608e-01 0.001 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.989331e-01 0.000 0 0
Sensory Perception R-HSA-9709957 9.993593e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 9.999989e-01 0.000 0 0
Metabolism R-HSA-1430728 9.999999e-01 0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways