KHS1

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0A2R8Y4L2 S95 Sugiyama HNRNPA1L3 HNRNPA1P48 RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED
A5A3E0 T789 Sugiyama POTEF A26C1B YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPVLLTEAT
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
O00303 T119 Sugiyama EIF3F EIF3S5 LASIVDSYERRNEGAARVIGtLLGtVDKHSVEVTNCFSVPH
O00303 T123 Sugiyama EIF3F EIF3S5 VDSYERRNEGAARVIGtLLGtVDKHSVEVTNCFSVPHNEsE
O00541 S282 Sugiyama PES1 EGTyALDSESCMEKLAALsAsLARVVVPATEEEAEVDEFPt
O14556 T301 Sugiyama GAPDHS GAPD2 GAPDH2 GAPDS HSD-35 HSD35 ASTGAAKAVTKVIPELKGKLtGMAFRVPTPDVSVVDLTCRL
O14744 T80 Sugiyama PRMT5 HRMT1L5 IBP72 JBP1 SKB1 KNRPGPQTRSDLLLSGRDWNtLIVGKLSPWIRPDSKVEKIR
O14908 T238 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 FDMISQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPs
O14908 T242 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 SQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPsAFEE
O15067 S1053 Sugiyama PFAS KIAA0361 RGLRERMGPSYCLPPTFPKAsVPREPGGPsPRVAILREEGS
O15067 T591 Sugiyama PFAS KIAA0361 NRDFLTHVSARERCPACFVGtITGDRRIVLVDDRECPVRRN
O15143 S323 Sugiyama ARPC1B ARC41 QNLDKKAssEGGtAAGAGLDsLHKNsVsQIsVLsGGKAKCS
O15212 T107 Sugiyama PFDN6 HKE2 PFD6 IKRYESQLRDLERQsEQQREtLAQLQQEFQRAQAAKAGAPG
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O43390 T137 Sugiyama HNRNPR HNRPR ESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O43399 T146 Sugiyama TPD52L2 yKKTQETLsQAGQKtsAALstVGsAIsRKLGDMRNsAtFKs
O43707 S507 Sugiyama ACTN4 DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43707 Y441 Sugiyama ACTN4 KAsIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEs
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60506 T134 Sugiyama SYNCRIP HNRPQ NSAP1 DSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O75390 T335 Sugiyama CS LQKEVGKDVSDEKLRDYIWNtLNSGRVVPGyGHAVLRKTDP
O75475 Y18 Sugiyama PSIP1 DFS70 LEDGF PSIP2 ___MTRDFKPGDLIFAKMKGyPHWPARVDEVPDGAVKPPTN
O75821 T240 Sugiyama EIF3G EIF3S4 DGAsRRGESMQPNRRADDNAtIRVtNLSEDTRETDLQELFR
O75821 T27 Sugiyama EIF3G EIF3S4 DsKPsWADQVEEEGEDDKCVtsELLKGIPLAtGDtsPEPEL
O94776 S433 Sugiyama MTA2 MTA1L1 PID ATRGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQt
O95218 T50 Sugiyama ZRANB2 ZIS ZNF265 SCNRCGREKTTEAKMMKAGGtEIGKtLAEKSRGLFsANDWQ
O95218 T55 Sugiyama ZRANB2 ZIS ZNF265 GREKTTEAKMMKAGGtEIGKtLAEKSRGLFsANDWQCKTCs
O95347 S664 Sugiyama SMC2 CAPE SMC2L1 PRO0324 RIMTRTVtLGGDVFDPHGtLsGGARSQAASILTKFQELKDV
O95347 T651 Sugiyama SMC2 CAPE SMC2L1 PRO0324 DNMDNAKKVAFDKRIMTRTVtLGGDVFDPHGtLsGGARSQA
O95347 T662 Sugiyama SMC2 CAPE SMC2L1 PRO0324 DKRIMTRTVtLGGDVFDPHGtLsGGARSQAASILTKFQELK
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95757 S579 Sugiyama HSPA4L APG1 HSPH3 OSP94 SAVSDKQDRLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNs
O95757 S586 Sugiyama HSPA4L APG1 HSPH3 OSP94 DRLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGK
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00338 S319 Sugiyama LDHA PIG19 GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______
P00338 S69 Sugiyama LDHA PIG19 ALVDVIEDKLKGEMMDLQHGsLFLRTPKIVSGKDyNVTANs
P00338 T275 Sugiyama LDHA PIG19 SVADLAESIMKNLRRVHPVstMIKGLYGIKDDVFLSVPCIL
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00492 S92 Sugiyama HPRT1 HPRT YKFFADLLDYIKALNRNSDRsIPMtVDFIRLKsYCNDQsTG
P00492 T96 Sugiyama HPRT1 HPRT ADLLDYIKALNRNSDRsIPMtVDFIRLKsYCNDQsTGDIKV
P00558 S390 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 IIGGGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPG
P00558 S399 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 T369 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV
P00558 T376 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P04040 T361 Sugiyama CAT PGIEASPDKMLQGRLFAyPDtHRHRLGPNyLHIPVNCPyRA
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 T119 Sugiyama ALDOA ALDA KsKGGVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYK
P04075 T124 Sugiyama ALDOA ALDA VVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGAD
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04080 S83 Sugiyama CSTB CST6 STFB DFVHLRVFQsLPHENKPLtLsNyQTNKAKHDELtyF_____
P04080 T81 Sugiyama CSTB CST6 STFB DEDFVHLRVFQsLPHENKPLtLsNyQTNKAKHDELtyF___
P04080 Y85 Sugiyama CSTB CST6 STFB VHLRVFQsLPHENKPLtLsNyQTNKAKHDELtyF_______
P04083 S173 Sugiyama ANXA1 ANX1 LPC1 NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG
P04083 S182 Sugiyama ANXA1 ANX1 LPC1 RDLAKDItsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsD
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 T229 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 AstGAAKAVGKVIPELNGKLtGMAFRVPtANVsVVDLtCRL
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04792 T91 Sugiyama HSPB1 HSP27 HSP28 PAYsRALsRQLssGVsEIRHtADRWRVsLDVNHFAPDELtV
P05187 T181 Sugiyama ALPP PLAP AGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASAR
P05187 T185 Sugiyama ALPP PLAP VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05455 T120 Sugiyama SSB VTDEyKNDVKNRsVYIKGFPtDAtLDDIKEWLEDKGQVLNI
P05455 T123 Sugiyama SSB EyKNDVKNRsVYIKGFPtDAtLDDIKEWLEDKGQVLNIQMR
P05455 T302 Sugiyama SSB ALGKAKDANNGNLQLRNKEVtWEVLEGEVEKEALKKIIEDQ
P05783 S399 Sugiyama KRT18 CYK18 PIG46 TYRRLLEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVV
P05783 T404 Sugiyama KRT18 CYK18 PIG46 LEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVVsETND
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S291 Sugiyama KRT8 CYK8 ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P05787 S330 Sugiyama KRT8 CYK8 MNRNISRLQAEIEGLKGQRAsLEAAIADAEQRGELAIKDAN
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 T55 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP
P06733 T72 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NDKtRYMGKGVSKAVEHINKtIAPALVsKKLNVtEQEKIDK
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T276 Sugiyama LDHB SVADLIESMLKNLSRIHPVStMVKGMYGIENEVFLSLPCIL
P07195 T302 Sugiyama LDHB YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 S390 Sugiyama PGK2 PGKB VIGGGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPG
P07205 S399 Sugiyama PGK2 PGKB CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 T117 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB RGyPtIKFFRNGDTASPKEytAGREADDIVNWLKKRTGPAA
P07237 T413 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB YAPWCGHCKQLAPIWDKLGEtyKDHENIVIAKMDstANEVE
P07437 S115 Sugiyama TUBB TUBB5 OK/SW-cl.56 sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 T312 Sugiyama TUBB TUBB5 OK/SW-cl.56 QVFDAKNMMAACDPRHGRyLtVAAVFRGRMsMKEVDEQMLN
P07437 T72 Sugiyama TUBB TUBB5 OK/SW-cl.56 NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
P07737 T65 Sugiyama PFN1 PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs
P07814 T1506 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 LCELQPGAKCVCGKNPAKyytLFGRsy______________
P07814 T707 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 VsPysCKEAPCVLIyIPDGHtKEMPTSGSKEKTKVEATKNE
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S169 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA TVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILH
P07900 S476 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA RKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKHIyyItG
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S52 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs
P07900 S63 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN
P07900 T171 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILHLK
P07900 T317 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P07900 T467 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKEN
P07900 T624 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA yGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIE
P07900 T645 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL
P07900 T65 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQ
P07900 T88 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA sKLDsGKELHINLIPNKQDRtLtIVDtGIGMTKADLINNLG
P07900 T90 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LDsGKELHINLIPNKQDRtLtIVDtGIGMTKADLINNLGtI
P07900 T94 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KELHINLIPNKQDRtLtIVDtGIGMTKADLINNLGtIAKSG
P07900 Y465 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IKLGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMK
P08195 S134 Sugiyama SLC3A2 MDU1 ELNELEPEKQPMNAAsGAAMsLAGAEKNGLVKIKVAEDEAE
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S164 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB VVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILH
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S58 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN
P08238 T166 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILHLK
P08238 T309 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238 T60 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQ
P08238 T616 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE
P08238 T637 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL
P08238 T83 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sKLDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLG
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T89 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P08758 S37 Sugiyama ANXA5 ANX5 ENX2 PP4 ERADAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAF
P08758 T111 Sugiyama ANXA5 ANX5 ENX2 PP4 yDAyELKHALKGAGTNEKVLtEIIAsRtPEELRAIKQVyEE
P08758 T40 Sugiyama ANXA5 ANX5 ENX2 PP4 DAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTL
P08758 T43 Sugiyama ANXA5 ANX5 ENX2 PP4 tLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTLFGR
P08758 T8 Sugiyama ANXA5 ANX5 ENX2 PP4 _____________MAQVLRGtVtDFPGFDERADAEtLRKAM
P09211 T62 Sugiyama GSTP1 FAEES3 GST3 GsLKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGK
P09211 T68 Sugiyama GSTP1 FAEES3 GST3 CLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQEAA
P09211 Y64 Sugiyama GSTP1 FAEES3 GST3 LKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQ
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09417 S163 Sugiyama QDPR DHPR SDR33C1 GTPGMIGYGMAKGAVHQLCQsLAGKNSGMPPGAAAIAVLPV
P09429 S35 Sugiyama HMGB1 HMG1 syAFFVQtCREEHKKKHPDAsVNFsEFsKKCsERWKtMsAK
P09651 S365 Sugiyama HNRNPA1 HNRPA1 GQyFAKPRNQGGyGGssssssyGsGRRF_____________
P09651 S368 Sugiyama HNRNPA1 HNRPA1 FAKPRNQGGyGGssssssyGsGRRF________________
P09651 S95 Sugiyama HNRNPA1 HNRPA1 RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED
P09651 Y366 Sugiyama HNRNPA1 HNRPA1 QyFAKPRNQGGyGGssssssyGsGRRF______________
P09874 S185 Sugiyama PARP1 ADPRT PPOL KNREELGFRPEYsAsQLKGFsLLAtEDKEALKKQLPGVKSE
P09923 T178 Sugiyama ALPI AGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASAR
P09923 T182 Sugiyama ALPI VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC
P0CG38 T789 Sugiyama POTEI YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
P0CG39 T752 Sugiyama POTEJ YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
P0DPH7 T334 Sugiyama TUBA3C TUBA2 ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
P0DPH7 T41 Sugiyama TUBA3C TUBA2 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P10412 S36 Sugiyama H1-4 H1F4 HIST1H1E EKtPVKKKARKsAGAAKRKAsGPPVsELItKAVAASKERsG
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10412 S58 Sugiyama H1-4 H1F4 HIST1H1E PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P10515 S98 Sugiyama DLAT DLTA LGSPGRRYYSLPPHQKVPLPsLsPtMQAGtIARWEKKEGDK
P10515 T102 Sugiyama DLAT DLTA GRRYYSLPPHQKVPLPsLsPtMQAGtIARWEKKEGDKINEG
P10515 T107 Sugiyama DLAT DLTA SLPPHQKVPLPsLsPtMQAGtIARWEKKEGDKINEGDLIAE
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P10809 T173 Sugiyama HSPD1 HSP60 AELKKQsKPVttPEEIAQVAtIsANGDKEIGNIIsDAMKKV
P10809 T206 Sugiyama HSPD1 HSP60 IsDAMKKVGRKGVITVKDGKtLNDELEIIEGMKFDRGyIsP
P10809 T231 Sugiyama HSPD1 HSP60 LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI
P10809 Y223 Sugiyama HSPD1 HSP60 DGKtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAy
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 S432 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGERAMTKD
P11142 T138 Sugiyama HSPA8 HSC70 HSP73 HSPA10 EVSSMVLTKMKEIAEAyLGKtVTNAVVtVPAyFNDsQRQAt
P11142 T145 Sugiyama HSPA8 HSC70 HSP73 HSPA10 TKMKEIAEAyLGKtVTNAVVtVPAyFNDsQRQAtKDAGtIA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11142 T586 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DKQKILDKCNEIINWLDKNQtAEKEEFEHQQKELEKVCNPI
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11586 S129 Sugiyama MTHFD1 MTHFC MTHFD INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP
P11586 T128 Sugiyama MTHFD1 MTHFC MTHFD SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt
P11940 T191 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 GRFKSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLF
P11940 T319 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KNLDDGIDDERLRKEFsPFGtItsAKVMMEGGRSKGFGFVC
P11940 T379 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 AtKPLyVALAQRKEERQAHLtNQyMQRMASVRAVPNPVINP
P11940 T71 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 sLGyAyVNFQQPADAERALDtMNFDVIKGKPVRIMWSQRDP
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12268 S416 Sugiyama IMPDH2 IMPD2 APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK
P12268 S508 Sugiyama IMPDH2 IMPD2 LKFEKRtssAQVEGGVHsLHsyEKRLF______________
P12268 Y509 Sugiyama IMPDH2 IMPD2 KFEKRtssAQVEGGVHsLHsyEKRLF_______________
P12270 T1039 Sugiyama TPR QDDKRRAIESMEQQLSELKKtLSSVQNEVQEALQRASTALS
P12277 T327 Sugiyama CKB CKBB KFsEVLKRLRLQKRGtGGVDtAAVGGVFDVsNADRLGFSEV
P12814 T490 Sugiyama ACTN1 PsVNARCQKICDQWDNLGALtQKRREALERTEKLLETIDQL
P12956 T302 Sugiyama XRCC6 G22P1 KPPPIKLYRETNEPVKTKTRtFNtstGGLLLPsDtKRSQIY
P12956 T305 Sugiyama XRCC6 G22P1 PIKLYRETNEPVKTKTRtFNtstGGLLLPsDtKRSQIYGSR
P13639 S418 Sugiyama EEF2 EF2 ISKMVPTSDKGRFyAFGRVFsGLVsTGLKVRIMGPNytPGK
P13639 S422 Sugiyama EEF2 EF2 VPTSDKGRFyAFGRVFsGLVsTGLKVRIMGPNytPGKKEDL
P13639 T34 Sugiyama EEF2 EF2 DKKANIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEt
P13639 T484 Sugiyama EEF2 EF2 VPCGNIVGLVGVDQFLVKtGtIttFEHAHNMRVMKFsVsPV
P13639 T5 Sugiyama EEF2 EF2 ________________MVNFtVDQIRAIMDKKANIRNMsVI
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13667 T238 Sugiyama PDIA4 ERP70 ERP72 KAAKELSKRSPPIPLAKVDAtAETDLAKRFDVsGyPTLKIF
P13667 T380 Sugiyama PDIA4 ERP70 ERP72 PEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGHR
P13796 T174 Sugiyama LCP1 PLS2 FNAVGDGIVLCKMINLSVPDtIDERTINKKKLTPFTIQENL
P13797 T177 Sugiyama PLS3 FKAVGDGIVLCKMINLSVPDtIDERAINKKKLTPFIIQENL
P13929 T19 Sugiyama ENO3 __MAMQKIFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGA
P13929 T26 Sugiyama ENO3 IFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGAstGIyEA
P14314 S126 Sugiyama PRKCSH G19P1 yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14314 S478 Sugiyama PRKCSH G19P1 DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 T45 Sugiyama PKM OIP3 PK2 PK3 PKM2 TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14618 T80 Sugiyama PKM OIP3 PK2 PK3 PKM2 tLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAs
P14618 T87 Sugiyama PKM OIP3 PK2 PK3 PKM2 sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P14625 S514 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK
P14625 S523 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 RtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAG
P14625 T150 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 EELTVKIKCDKEKNLLHVtDtGVGMtREELVKNLGTIAKsG
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P14625 T450 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 LNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRKTLD
P14625 T519 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 DHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIy
P14866 S544 Sugiyama HNRNPL HNRPL P/OKcl.14 LGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLNH
P15259 S189 Sugiyama PGAM2 PGAMM EEIVPQIKAGKRVLIAAHGNsLRGIVKHLEGMSDQAIMELN
P15259 T96 Sugiyama PGAM2 PGAMM QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQVKIWR
P15311 T299 Sugiyama EZR VIL2 RILQLCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQLE
P15531 S120 Sugiyama NME1 NDPKA NM23 KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P15531 S122 Sugiyama NME1 NDPKA NM23 GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P15880 S206 Sugiyama RPS2 RPS4 GRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDCytsA
P15880 T202 Sugiyama RPS2 RPS4 CKVTGRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDC
P15880 T230 Sugiyama RPS2 RPS4 PKKLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysy
P15880 T232 Sugiyama RPS2 RPS4 KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P16083 S80 Sugiyama NQO2 NMOR2 LSNPEVFNyGVEtHEAyKQRsLAsDITDEQKKVREADLVIF
P16402 S37 Sugiyama H1-3 H1F3 HIST1H1D KtPVKKKAKKAGATAGKRKAsGPPVsELItKAVAASKERsG
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16402 S59 Sugiyama H1-3 H1F3 HIST1H1D PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P16403 S36 Sugiyama H1-2 H1F2 HIST1H1C EKAPVKKKAAKKAGGtPRKAsGPPVsELItKAVAASKERsG
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S58 Sugiyama H1-2 H1F2 HIST1H1C PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P16949 S46 Sugiyama STMN1 C1orf215 LAP18 OP18 PRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAEERRKsHEA
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17987 S35 Sugiyama TCP1 CCT1 CCTA EtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTIT
P18621 S111 Sugiyama RPL17 LLHMLKNAESNAELKGLDVDsLVIEHIQVNKAPKMRRRTYR
P18621 T29 Sugiyama RPL17 ENPtKsCKSRGSNLRVHFKNtRETAQAIKGMHIRKATKYLK
P18669 S189 Sugiyama PGAM1 PGAMA CDABP0006 EEIVPQIKEGKRVLIAAHGNsLRGIVKHLEGLSEEAIMELN
P18669 T96 Sugiyama PGAM1 PGAMA CDABP0006 QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P19338 T301 Sugiyama NCL KKEMAKQKAAPEAKKQKVEGtEPttAFNLFVGNLNFNKSAP
P19338 T304 Sugiyama NCL MAKQKAAPEAKKQKVEGtEPttAFNLFVGNLNFNKSAPELK
P19338 T464 Sugiyama NCL KTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsGE
P20042 S67 Sugiyama EIF2S2 EIF2B EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK
P20290 S126 Sugiyama BTF3 NACB OK/SW-cl.8 VNMFTNQGTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEM
P20290 T131 Sugiyama BTF3 NACB OK/SW-cl.8 NQGTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsIL
P20290 T133 Sugiyama BTF3 NACB OK/SW-cl.8 GTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQ
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20618 S162 Sugiyama PSMB1 PSC5 DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG
P20618 Y158 Sugiyama PSMB1 PSC5 IGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLD
P22090 S204 Sugiyama RPS4Y1 RPS4Y PRO2646 IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN
P22314 T600 Sugiyama UBA1 A1S9T UBE1 ARMYMDRRCVYYRKPLLESGtLGtKGNVQVVIPFLTESySS
P22314 T633 Sugiyama UBA1 A1S9T UBE1 FLTESySSSQDPPEKSIPICtLKNFPNAIEHTLQWARDEFE
P22314 T682 Sugiyama UBA1 A1S9T UBE1 NVNQyLtDPKFVERtLRLAGtQPLEVLEAVQRSLVLQRPQT
P22626 S212 Sugiyama HNRNPA2B1 HNRPA2B1 EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD
P22626 T140 Sugiyama HNRNPA2B1 HNRPA2B1 KEDTEEHHLRDyFEEYGKIDtIEIItDRQsGKKRGFGFVtF
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23284 T108 Sugiyama PPIB CYPB YKNSKFHRVIKDFMIQGGDFtRGDGtGGKsIyGERFPDENF
P23381 S378 Sugiyama WARS1 IFI53 WARS WRS sIFLtDtAKQIKTKVNKHAFsGGRDtIEEHRQFGGNCDVDV
P23381 T383 Sugiyama WARS1 IFI53 WARS WRS DtAKQIKTKVNKHAFsGGRDtIEEHRQFGGNCDVDVSFMYL
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23588 S359 Sugiyama EIF4B RstPKEDDSsASTSQSTRAAsIFGGAKPVDtAAREREVEER
P23588 T369 Sugiyama EIF4B ASTSQSTRAAsIFGGAKPVDtAAREREVEERLQKEQEKLQR
P23921 T751 Sugiyama RRM1 RR1 GLKTGMYyLRTRPAANPIQFtLNKEKLKDKEKVSKEEEEKE
P24752 S69 Sugiyama ACAT1 ACAT MAT RTPIGSFLGSLSLLPATKLGsIAIQGAIEKAGIPKEEVKEA
P25705 S198 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK
P25786 T11 Sugiyama PSMA1 HC2 NU PROS30 PSC2 __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ
P25789 T10 Sugiyama PSMA4 HC9 PSC9 ___________MSRRyDsRttIFsPEGRLYQVEYAMEAIGH
P25789 Y5 Sugiyama PSMA4 HC9 PSC9 ________________MSRRyDsRttIFsPEGRLYQVEYAM
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26038 T299 Sugiyama MSN RILALCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQME
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26373 T24 Sugiyama RPL13 BBC1 OK/SW-cl.46 SRNGMVLKPHFHKDWQRRVAtWFNQPARKIRRRKARQAKAR
P26641 T150 Sugiyama EEF1G EF1G PRO1608 NAKEEVRRILGLLDAYLKTRtFLVGERVTLADITVVCTLLW
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27144 S195 Sugiyama AK4 AK3 AK3L1 KDVAKPVIELYKSRGVLHQFsGtEtNKIWPYVYTLFSNKIT
P27144 T199 Sugiyama AK4 AK3 AK3L1 KPVIELYKSRGVLHQFsGtEtNKIWPYVYTLFSNKITPIQS
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P28066 T161 Sugiyama PSMA5 LLFGGVDEKGPQLFHMDPsGtFVQCDARAIGsAsEGAQssL
P29401 S124 Sugiyama TKT ssDLDGHPVPKQAFtDVATGsLGQGLGAACGMAYTGKYFDK
P29401 T346 Sugiyama TKT AKLGHAsDRIIALDGDtKNstFsEIFKKEHPDRFIECYIAE
P29692 S119 Sugiyama EEF1D EF1D QELQQAIsKLEARLNVLEKssPGHRAtAPQtQHVsPMRQVE
P29692 S60 Sugiyama EEF1D EF1D ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL
P29692 T125 Sugiyama EEF1D EF1D IsKLEARLNVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKP
P29692 T129 Sugiyama EEF1D EF1D EARLNVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPA
P30040 S244 Sugiyama ERP29 C12orf8 ERP28 IARLIEKNKMSDGKKEELQKsLNILtAFQKKGAEKEEL___
P30040 T249 Sugiyama ERP29 C12orf8 ERP28 EKNKMSDGKKEELQKsLNILtAFQKKGAEKEEL________
P30043 T199 Sugiyama BLVRB FLR SCAN HDLGHFMLRCLttDEyDGHstyPsHQyQ_____________
P30048 S199 Sugiyama PRDX3 AOP1 SGLALRGLFIIDPNGVIKHLsVNDLPVGRSVEETLRLVKAF
P30048 S86 Sugiyama PRDX3 AOP1 TQHAPYFKGTAVVNGEFKDLsLDDFKGKYLVLFFYPLDFTF
P30050 T128 Sugiyama RPL12 EIVNIARQMRHRSLARELsGtIKEILGtAQsVGCNVDGRHP
P30050 T135 Sugiyama RPL12 QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI
P30050 T18 Sugiyama RPL12 ___MPPKFDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLs
P30050 T25 Sugiyama RPL12 FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30086 S60 Sugiyama PEBP1 PBP PEBP VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK
P30086 T101 Sugiyama PEBP1 PBP PEBP YREWHHFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLHRyV
P30086 T115 Sugiyama PEBP1 PBP PEBP NDIssGtVLsDyVGsGPPKGtGLHRyVWLVyEQDRPLKCDE
P30086 T167 Sugiyama PEBP1 PBP PEBP GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK
P30101 T485 Sugiyama PDIA3 ERP57 ERP60 GRP58 KKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKKKKAQEDL
P30626 T130 Sugiyama SRI IsFDTDRSGTVDPQELQKALttMGFRLsPQAVNSIAKRYst
P30626 T131 Sugiyama SRI sFDTDRSGTVDPQELQKALttMGFRLsPQAVNSIAKRYstN
P30740 S72 Sugiyama SERPINB1 ELANH2 MNEI PI2 AQLSKTFHFNTVEEVHSRFQsLNADINKRGASYILKLANRL
P31153 T262 Sugiyama MAT2A AMS2 MATA2 yHLQPsGRFVIGGPQGDAGLtGRKIIVDTYGGWGAHGGGAF
P31943 S269 Sugiyama HNRNPH1 HNRPH HNRPH1 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH
P31943 T282 Sugiyama HNRNPH1 HNRPH HNRPH1 RDLNyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtE
P31943 T286 Sugiyama HNRNPH1 HNRPH HNRPH1 yCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDIy
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948 T145 Sugiyama STIP1 MNPFNMPNLYQKLESDPRtRtLLSDPTYRELIEQLRNKPSD
P32929 T372 Sugiyama CTH AIMtHASVLKNDRDVLGISDtLIRLsVGLEDEEDLLEDLDQ
P32969 T186 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 TVKNKDIRKFLDGIyVsEKGtVQQADE______________
P33992 S417 Sugiyama MCM5 CDC46 CsPIGVytsGKGSSAAGLtAsVMRDPssRNFIMEGGAMVLA
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P35241 T299 Sugiyama RDX RILALCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQLE
P35579 S304 Sugiyama MYH9 AGEHLKTDLLLEPyNKyRFLsNGHVtIPGQQDKDMFQETME
P35579 T1208 Sugiyama MYH9 QEMRQKHsQAVEELAEQLEQtKRVKANLEKAKQtLENERGE
P35579 T309 Sugiyama MYH9 KTDLLLEPyNKyRFLsNGHVtIPGQQDKDMFQETMEAMRIM
P35637 S462 Sugiyama FUS TLS NECNQCKAPKPDGPGGGPGGsHMGGNyGDDRRGGRGGYDRG
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36578 S131 Sugiyama RPL4 RPL1 WHRRVNTTQKRyAICSALAAsALPALVMsKGHRIEEVPELP
P36578 S139 Sugiyama RPL4 RPL1 QKRyAICSALAAsALPALVMsKGHRIEEVPELPLVVEDKVE
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T69 Sugiyama RPL4 RPL1 RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P36578 Y122 Sugiyama RPL4 RPL1 FAPTKTWRRWHRRVNTTQKRyAICSALAAsALPALVMsKGH
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P37802 T84 Sugiyama TAGLN2 KIAA0120 CDABP0035 ELINALYPEGQAPVKKIQAstMAFKQMEQIsQFLQAAERYG
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39019 T55 Sugiyama RPS19 DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P39023 T189 Sugiyama RPL3 OK/SW-cl.32 RLLPLRQKKAHLMEIQVNGGtVAEKLDWARERLEQQVPVNQ
P39687 S117 Sugiyama ANP32A C15orf1 LANP MAPM PHAP1 GNKIKDLstIEPLKKLENLKsLDLFNCEVtNLNDyRENVFK
P39748 S255 Sugiyama FEN1 RAD2 CESIRGIGPKRAVDLIQKHKsIEEIVRRLDPNKYPVPENWL
P40227 T147 Sugiyama CCT6A CCT6 CCTZ KEKALQFLEEVKVSREMDREtLIDVARTSLRTKVHAELADV
P40227 T82 Sugiyama CCT6A CCT6 CCTZ VLLHEMQIQHPTASLIAKVAtAQDDITGDGTTsNVLIIGEL
P40261 S213 Sugiyama NNMT LVIMDALKSSYYMIGEQKFSsLPLGREAVEAAVKEAGYTIE
P40429 T155 Sugiyama RPL13A FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P41091 T41 Sugiyama EIF2S3 EIF2G ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
P41091 T46 Sugiyama EIF2S3 EIF2G tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHt
P42166 T137 Sugiyama TMPO LAP2 NEDLLDQLVKyGVNPGPIVGttRKLYEKKLLKLREQGtEsR
P42167 T137 Sugiyama TMPO LAP2 NEDLLDQLVKyGVNPGPIVGtTRKLYEKKLLKLREQGTESR
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P46776 T72 Sugiyama RPL27A yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK
P46776 T95 Sugiyama RPL27A LDKLWtLVsEQtRVNAAKNKtGAAPIIDVVRsGyyKVLGKG
P46776 Y52 Sugiyama RPL27A RGNAGGLHHHRINFDKyHPGyFGKVGMKHYHLKRNQsFCPt
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 T177 Sugiyama RPL5 MSTP030 NKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHRK
P46778 T124 Sugiyama RPL21 sFLKRVKENDQKKKEAKEKGtWVQLKRQPAPPREAHFVRTN
P46782 S75 Sugiyama RPS5 RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46783 T148 Sugiyama RPS10 RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P47712 S729 Sugiyama PLA2G4A CPLA2 PLA2G4 KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P48643 S51 Sugiyama CCT5 CCTE KIAA0098 LEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtVT
P48643 T47 Sugiyama CCT5 CCTE KIAA0098 RLMGLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGD
P48643 T50 Sugiyama CCT5 CCTE KIAA0098 GLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtV
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P49327 T1999 Sugiyama FASN FAS LLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFVVF
P49327 T715 Sugiyama FASN FAS LQELKKVIREPKPRSARWLstsIPEAQWHssLARTSSAEYN
P49368 T430 Sugiyama CCT3 CCTG TRIC5 GGGASEMAVAHALTEKSKAMtGVEQWPyRAVAQALEVIPRT
P49368 T459 Sugiyama CCT3 CCTG TRIC5 AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG
P49411 T433 Sugiyama TUFM LRQPMILEKGQRFTLRDGNRtIGTGLVTNTLAMTEEEKNIK
P49589 S34 Sugiyama CARS1 CARS VQPQWsPPAGtQPCRLHLyNsLtRNKEVFIPQDGKKVTWYC
P49841 S9 SIGNOR|EPSD|PSP GSK3B ____________MSGRPRttsFAEsCKPVQQPsAFGsMKVS
P50395 T425 Sugiyama GDI2 RABGDIB DAttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED
P50914 T43 Sugiyama RPL14 KLVAIVDVIDQNRALVDGPCtQVRRQAMPFKCMQLTDFILK
P50990 S162 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 ILPNLVCCsAKNLRDIDEVssLLRTSIMSKQyGNEVFLAKL
P50990 T374 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 EVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDD
P50991 T69 Sugiyama CCT4 CCTD SRB RtsLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAAR
P50991 T76 Sugiyama CCT4 CCTD SRB GMDKMIQDGKGDVtItNDGAtILKQMQVLHPAARMLVELSK
P51149 T168 Sugiyama RAB7A RAB7 NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE
P51858 S83 Sugiyama HDGF HMG1L2 LFPyEEsKEKFGKPNKRKGFsEGLWEIENNPtVKASGYQSs
P51858 T184 Sugiyama HDGF HMG1L2 DsPKRPKEAENPEGEEKEAAtLEVERPLPMEVEKNstPsEP
P51858 T94 Sugiyama HDGF HMG1L2 GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP
P51858 Y23 Sugiyama HDGF HMG1L2 RSNRQKEYKCGDLVFAKMKGyPHWPARIDEMPEAAVKstAN
P51991 S370 Sugiyama HNRNPA3 HNRPA3 sFGGRssGsPyGGGyGsGGGsGGyGsRRF____________
P53621 T821 Sugiyama COPA IMPLDTNWPLLTVSKGFFEGtIAsKGKGGALAADIDIDTVG
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P55036 S358 Sugiyama PSMD4 MCB1 VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_
P55060 S931 Sugiyama CSE1L CAS XPO2 KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL
P55209 S69 Sugiyama NAP1L1 NRP LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA
P55209 T64 Sugiyama NAP1L1 NRP QNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNL
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P55795 S269 Sugiyama HNRNPH2 FTP3 HNRPH2 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH
P56192 S127 Sugiyama MARS1 MARS GKKGEDVLGSVRRALTHIDHsLSRQNCPFLAGETESLADIV
P56192 S812 Sugiyama MARS1 MARS GHQIGTVSPLFQKLENDQIEsLRQRFGGGQAKtsPKPAVVE
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T173 Sugiyama TPI1 TPI DNVKDWSKVVLAyEPVWAIGtGKtATPQQAQEVHEKLRGWL
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T76 Sugiyama TPI1 TPI LDPKIAVAAQNCyKVTNGAFtGEIsPGMIKDCGAtWVVLGH
P60660 Y86 Sugiyama MYL6 DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T203 Sugiyama ACTB RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 T89 Sugiyama ACTB YPIEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAP
P60709 Y188 Sugiyama ACTB GyALPHAILRLDLAGRDLTDyLMKILtERGysFtttAEREI
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P60842 T80 Sugiyama EIF4A1 DDX2A EIF4A QRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDLKA
P61221 S186 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 AIIKPQYVDQIPKAAKGtVGsILDRKDETKTQAIVCQQLDL
P61221 T183 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 DLKAIIKPQYVDQIPKAAKGtVGsILDRKDETKTQAIVCQQ
P61247 S203 Sugiyama RPS3A FTE1 MFTL EVVNKLIPDsIGKDIEKACQsIyPLHDVFVRKVKMLKKPKF
P61247 S237 Sugiyama RPS3A FTE1 MFTL MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE
P61247 S238 Sugiyama RPS3A FTE1 MFTL LKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyEP
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 S23 Sugiyama RPL26 FNPFVtsDRsKNRKRHFNAPsHIRRKIMssPLSKELRQKYN
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61254 T93 Sugiyama RPL26 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
P61313 T80 Sugiyama RPL15 EC45 TCBAP0781 VIyRIRVRRGGRKRPVPKGAtyGKPVHHGVNQLKFARsLQs
P61313 Y6 Sugiyama RPL15 EC45 TCBAP0781 _______________MGAYKyIQELWRKKQSDVMRFLLRVR
P61513 S21 Sugiyama RPL37A MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQHAKYTCSF
P61513 T16 Sugiyama RPL37A _____MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQHAK
P61513 Y14 Sugiyama RPL37A _______MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQH
P61604 T79 Sugiyama HSPE1 EIQPVsVKVGDKVLLPEyGGtKVVLDDKDyFLFRDGDILGK
P61604 Y76 Sugiyama HSPE1 KGGEIQPVsVKVGDKVLLPEyGGtKVVLDDKDyFLFRDGDI
P61758 S157 Sugiyama VBP1 PFDN3 IDEAQALLEKNLSTATKNLDsLEEDLDFLRDQFTtTEVNMA
P61758 T171 Sugiyama VBP1 PFDN3 ATKNLDsLEEDLDFLRDQFTtTEVNMARVyNWDVKRRNKDD
P61916 T44 Sugiyama NPC2 HE1 FKDCGsVDGVIKEVNVsPCPtQPCQLSKGQSYSVNVTFTSN
P61970 S58 Sugiyama NUTF2 NTF2 CLTWEGQQFQGKAAIVEKLssLPFQKIQHSITAQDHQPTPD
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P62081 T172 Sugiyama RPS7 RLIKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEF
P62241 S160 Sugiyama RPS8 OK/SW-cl.83 KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62258 T114 Sugiyama YWHAE KLICCDILDVLDKHLIPAANtGEsKVFyyKMKGDYHRyLAE
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62263 S69 Sugiyama RPS14 PRO2640 GKETICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELG
P62263 T140 Sugiyama RPS14 PRO2640 ARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL_________
P62266 S45 Sugiyama RPS23 KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62266 T34 Sugiyama RPS23 RSHRRDQKWHDKQYKKAHLGtALKANPFGGAsHAKGIVLEK
P62269 T60 Sugiyama RPS18 D6S218E YAHVVLRKADIDLTKRAGELtEDEVERVItIMQNPRQYKIP
P62269 T69 Sugiyama RPS18 D6S218E DIDLTKRAGELtEDEVERVItIMQNPRQYKIPDWFLNRQKD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62277 T24 Sugiyama RPS13 MHAPGKGLsQsALPyRRsVPtWLKLTsDDVKEQIyKLAKKG
P62280 S74 Sugiyama RPS11 tyIDKKCPFTGNVsIRGRILsGVVTKMKMQRTIVIRRDYLH
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62424 T142 Sugiyama RPL7A SURF-3 SURF3 AAGKGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVD
P62424 T145 Sugiyama RPL7A SURF-3 SURF3 KGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVDPIE
P62424 T84 Sugiyama RPL7A SURF-3 SURF3 QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP
P62701 S204 Sugiyama RPS4X CCG2 RPS4 SCAR tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN
P62701 T177 Sugiyama RPS4X CCG2 RPS4 SCAR NDtIQIDLEtGKITDFIKFDtGNLCMVtGGANLGRIGVITN
P62701 T184 Sugiyama RPS4X CCG2 RPS4 SCAR LEtGKITDFIKFDtGNLCMVtGGANLGRIGVITNRERHPGs
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y190 Sugiyama ACTA2 ACTSA ACTVS GIG46 GyALPHAIMRLDLAGRDLTDyLMKILTERGysFVttAEREI
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62750 T126 Sugiyama RPL23A KHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAYVRLAPDyDA
P62826 S135 Sugiyama RAN ARA24 OK/SW-cl.81 IPIVLCGNKVDIKDRKVKAKsIVFHRKKNLQyyDIsAKSNy
P62826 T21 Sugiyama RAN ARA24 OK/SW-cl.81 MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA
P62826 T32 Sugiyama RAN ARA24 OK/SW-cl.81 KLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGVEVHPLVF
P62851 T110 Sugiyama RPS25 ELLsKGLIKLVSKHRAQVIytRNtKGGDAPAAGEDA_____
P62851 T113 Sugiyama RPS25 sKGLIKLVSKHRAQVIytRNtKGGDAPAAGEDA________
P62857 S41 Sugiyama RPS28 tGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLLEs
P62857 T38 Sugiyama RPS28 LGRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtL
P62857 T57 Sugiyama RPS28 DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________
P62899 S15 Sugiyama RPL31 ______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG
P62899 T22 Sugiyama RPL31 APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 T143 Sugiyama RPL8 RGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANR
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 T157 Sugiyama PPIA CYPA NIVEAMERFGsRNGKTSKKItIADCGQLE____________
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63104 T205 Sugiyama YWHAZ PEKACSLAKtAFDEAIAELDtLsEEsyKDstLIMQLLRDNL
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T203 Sugiyama ACTG1 ACTG RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 T89 Sugiyama ACTG1 ACTG YPIEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAP
P63261 Y188 Sugiyama ACTG1 ACTG GyALPHAILRLDLAGRDLTDyLMKILtERGysFtttAEREI
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y189 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG GyALPHAIMRLDLAGRDLTDyLMKILTERGysFVttAEREI
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809 S209 Sugiyama YBX1 NSEP1 YB1 RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67936 T237 Sugiyama TPM4 IDDLEEKLAQAKEENVGLHQtLDQtLNELNCI_________
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 T91 Sugiyama ACTC1 ACTC yPIEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAP
P68032 Y190 Sugiyama ACTC1 ACTC GyALPHAIMRLDLAGRDLTDyLMKILTERGysFVttAEREI
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104 T23 Sugiyama EEF1A1 EEF1A EF1A LENG7 KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
P68104 T261 Sugiyama EEF1A1 EEF1A EF1A LENG7 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
P68104 T269 Sugiyama EEF1A1 EEF1A EF1A LENG7 PLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFAPVNVttEV
P68104 T279 Sugiyama EEF1A1 EEF1A EF1A LENG7 IGtVPVGRVEtGVLKPGMVVtFAPVNVttEVKsVEMHHEAL
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 T91 Sugiyama ACTA1 ACTA yPIEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAP
P68133 Y190 Sugiyama ACTA1 ACTA GyALPHAIMRLDLAGRDLTDyLMKILTERGysFVttAEREI
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 T334 Sugiyama TUBA1B ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG
P68363 T41 Sugiyama TUBA1B WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P68431 T46 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P78371 T474 Sugiyama CCT2 99D8.1 CCTB AGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGIT
P78371 T69 Sugiyama CCT2 99D8.1 CCTB DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 T83 Sugiyama RPL24 QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098 T187 Sugiyama RPL19 KEARKRREERLQAKKEEIIKtLsKEEETKK___________
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P84243 T46 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q00610 S432 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 sPLLQYFGILLDQGQLNKyEsLELCRPVLQQGRKQLLEKWL
Q01105 S168 Sugiyama SET ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01518 T24 Sugiyama CAP1 CAP MQNLVERLERAVGRLEAVSHtsDMHRGyADsPsKAGAAPyV
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q01650 T45 Sugiyama SLC7A5 CD98LC LAT1 MPE16 KMLAAKsADGsAPAGEGEGVtLQRNITLLNGVAIIVGTIIG
Q02543 S123 Sugiyama RPL18A AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK
Q02543 T101 Sugiyama RPL18A WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA
Q02543 T107 Sugiyama RPL18A RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02543 T168 Sugiyama RPL18A SKIKFPLPHRVLRRQHKPRFttKRPNtFF____________
Q02543 T169 Sugiyama RPL18A KIKFPLPHRVLRRQHKPRFttKRPNtFF_____________
Q02878 S255 Sugiyama RPL6 TXREB1 tEKEKYEITEQRKIDQKAVDsQILPKIKAIPQLQGYLRSVF
Q02878 T118 Sugiyama RPL6 TXREB1 GDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQHVR
Q02878 T235 Sugiyama RPL6 TXREB1 AyFKKKKLRKPRHQEGEIFDtEKEKYEITEQRKIDQKAVDs
Q02878 T91 Sugiyama RPL6 TXREB1 RKYSAAKSKVEKKKKEKVLAtVtKPVGGDKNGGTRVVKLRK
Q04637 T718 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI GLGPRRsQQGPRKEPRKIIAtVLMtEDIKLNKAEKAWKPSS
Q04637 T722 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI RRsQQGPRKEPRKIIAtVLMtEDIKLNKAEKAWKPSSKRTA
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05639 T23 Sugiyama EEF1A2 EEF1AL STN KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
Q05639 T261 Sugiyama EEF1A2 EEF1AL STN PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06830 T18 Sugiyama PRDX1 PAGA PAGB TDPX2 ___MSSGNAKIGHPAPNFKAtAVMPDGQFKDIsLsDyKGKY
Q07020 T79 Sugiyama RPL18 PPLsLsRMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLK
Q07020 T85 Sugiyama RPL18 RMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRV
Q07020 T87 Sugiyama RPL18 IRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRVTS
Q07157 T1167 Sugiyama TJP1 ZO1 EQAPRAsALRHEEQPAPGyDtHGRLRPEAQPHPsAGPKPAE
Q12906 T300 Sugiyama ILF3 DRBF MPHOSPH4 NF90 ASGIVMPDGSGIYDPCEKEAtDAIGHLDRQQREDItQsAQH
Q12931 T641 Sugiyama TRAP1 HSP75 HSPC5 FLRMQQLAKTQEERAQLLQPtLEINPRHALIKKLNQLRASE
Q13247 T146 Sugiyama SRSF6 SFRS6 SRP55 LKDFMRQAGEVTYADAHKERtNEGVIEFRSYSDMKRALDKL
Q13283 S119 Sugiyama G3BP1 G3BP SNNNQALRRFMQtFVLAPEGsVANKFyVHNDIFRyQDEVFG
Q13283 S250 Sugiyama G3BP1 G3BP sssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGI
Q13283 S253 Sugiyama G3BP1 G3BP PAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPH
Q13283 T111 Sugiyama G3BP1 G3BP VVQVMGLLSNNNQALRRFMQtFVLAPEGsVANKFyVHNDIF
Q13283 T21 Sugiyama G3BP1 G3BP MVMEKPsPLLVGREFVRQyytLLNQAPDMLHRFYGKNssyV
Q13310 T191 Sugiyama PABPC4 APP1 PABP4 GRFKSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELF
Q13310 T71 Sugiyama PABPC4 APP1 PABP4 sLGyAyVNFQQPADAERALDtMNFDVIKGKPIRIMWSQRDP
Q13409 T617 Sugiyama DYNC1I2 DNCI2 DNCIC2 YDVGEQIAVPRNDEWARFGRtLAEINANRADAEEEAATRIP
Q13509 S115 Sugiyama TUBB3 TUBB4 SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13509 T312 Sugiyama TUBB3 TUBB4 QMFDAKNMMAACDPRHGRYLtVAtVFRGRMSMKEVDEQMLA
Q13509 T315 Sugiyama TUBB3 TUBB4 DAKNMMAACDPRHGRYLtVAtVFRGRMSMKEVDEQMLAIQS
Q13509 T72 Sugiyama TUBB3 TUBB4 NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF
Q13642 T138 Sugiyama FHL1 SLIM1 KGtVWHKDCFTCSNCKQVIGtGSFFPKGEDFyCVtCHETKF
Q13885 S115 Sugiyama TUBB2A TUBB2 sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q13885 T72 Sugiyama TUBB2A TUBB2 NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S1188 Sugiyama EIF3A EIF3S10 KIAA0139 PWRPLVKPGGWREKEKAREEsWGPPRESRPsEEREWDREKE
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14240 T81 Sugiyama EIF4A2 DDX2B EIF4F QRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEFKE
Q14247 T219 Sugiyama CTTN EMS1 yGIDKDKVDKsAVGFEyQGKtEKHESQKDyVKGFGGKFGVQ
Q14247 T68 Sugiyama CTTN EMS1 GHQEHINIHKLRENVFQEHQtLKEKELETGPKASHGyGGKF
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14568 S169 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 TVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILH
Q14568 S52 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS
Q14568 T171 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 ITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILHLK
Q14914 T83 Sugiyama PTGR1 LTB4DH MMGQQVAKVVESKNVALPKGtIVLAsPGWttHSISDGKDLE
Q14914 T93 Sugiyama PTGR1 LTB4DH ESKNVALPKGtIVLAsPGWttHSISDGKDLEKLLTEWPDTI
Q14974 S201 Sugiyama KPNB1 NTF97 MRKEEPSNNVKLAAtNALLNsLEFTKANFDKESERHFIMQV
Q14974 T195 Sugiyama KPNB1 NTF97 TAIIQGMRKEEPSNNVKLAAtNALLNsLEFTKANFDKESER
Q14980 S1991 Sugiyama NUMA1 NMP22 NUMA QPIQIAEGTGITTRQQRKRVsLEPHQGPGtPEsKKATSCFP
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15084 S88 Sugiyama PDIA6 ERP5 P5 TXNDC7 AATALKDVVKVGAVDADKHHsLGGQyGVQGFPtIKIFGSNK
Q15084 T100 Sugiyama PDIA6 ERP5 P5 TXNDC7 AVDADKHHsLGGQyGVQGFPtIKIFGSNKNRPEDYQGGRTG
Q15084 T395 Sugiyama PDIA6 ERP5 P5 TXNDC7 sFsEQGINEFLRELsFGRGstAPVGGGAFPtIVEREPWDGR
Q15084 T405 Sugiyama PDIA6 ERP5 P5 TXNDC7 LRELsFGRGstAPVGGGAFPtIVEREPWDGRDGELPVEDDI
Q15084 Y93 Sugiyama PDIA6 ERP5 P5 TXNDC7 KDVVKVGAVDADKHHsLGGQyGVQGFPtIKIFGSNKNRPED
Q15185 S39 Sugiyama PTGES3 P23 TEBP FCVEDSKDVNVNFEKsKLTFsCLGGsDNFKHLNEIDLFHCI
Q15185 S44 Sugiyama PTGES3 P23 TEBP SKDVNVNFEKsKLTFsCLGGsDNFKHLNEIDLFHCIDPNDs
Q15185 S72 Sugiyama PTGES3 P23 TEBP EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE
Q15293 S69 Sugiyama RCN1 RCN PPEDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVD
Q15293 T211 Sugiyama RCN1 RCN FTAFLHPEEFEHMKEIVVLEtLEDIDKNGDGFVDQDEyIAD
Q15293 T71 Sugiyama RCN1 RCN EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI
Q15369 T41 Sugiyama ELOC TCEB1 LISSDGHEFIVKREHALtsGtIKAMLSGPGQFAENETNEVN
Q15459 S508 Sugiyama SF3A1 SAP114 IGEEEIQKPEEKVTWDGHsGsMARTQQAAQANITLQEQIEA
Q15785 S160 Sugiyama TOMM34 URCC3 WRLKLPSIPLVPVsAQKRWNsLPSENHKEMAKSKSKETTAT
Q16576 T373 Sugiyama RBBP7 RBAP46 QsAEDAEDGPPELLFIHGGHtAKISDFSWNPNEPWVICSVS
Q16658 S237 Sugiyama FSCN1 FAN1 HSN SNL RsGKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALE
Q16658 T213 Sugiyama FSCN1 FAN1 HSN SNL HRFLRHDGRLVARPEPATGytLEFRsGKVAFRDCEGRyLAP
Q16658 T239 Sugiyama FSCN1 FAN1 HSN SNL GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs
Q16695 T46 Sugiyama H3-4 H3FT HIST3H3 ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q2VIR3 T41 Sugiyama EIF2S3B ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
Q2VIR3 T46 Sugiyama EIF2S3B tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHT
Q32P51 S95 Sugiyama HNRNPA1L2 HNRNPA1L TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q3ZCM7 S75 Sugiyama TUBB8 SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC
Q4G0X9 S553 Sugiyama CCDC40 KIAA1640 EIEAYKKSIMKEEEKNEKLAsILNRTETEATLLQKLTTQCL
Q52LJ0 T265 Sugiyama FAM98B KTDDIARIYQPKRYALSPKTtItMAHLLAAREDLSKIIRTs
Q52LJ0 T267 Sugiyama FAM98B DDIARIYQPKRYALSPKTtItMAHLLAAREDLSKIIRTsSG
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q562R1 Y189 Sugiyama ACTBL2 GYALPHAILRLDLAGRDLTDyLMKILTERGYNFTTTAEREI
Q58FF6 S34 Sugiyama HSP90AB4P IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN
Q58FF6 T36 Sugiyama HSP90AB4P LQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPNPR
Q58FF7 S58 Sugiyama HSP90AB3P HSP90BC IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF7 T489 Sugiyama HSP90AB3P HSP90BC YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME
Q58FF7 T60 Sugiyama HSP90AB3P HSP90BC LQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQ
Q58FF8 S58 Sugiyama HSP90AB2P HSP90BB IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8 T60 Sugiyama HSP90AB2P HSP90BB LWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQ
Q58FG1 T28 Sugiyama HSP90AA4P HSP90AD HSPCAL2 SKLDSGKEPHISLIPNKQDRtLtIVDtGIGMTKADLINNLG
Q58FG1 T30 Sugiyama HSP90AA4P HSP90AD HSPCAL2 LDSGKEPHISLIPNKQDRtLtIVDtGIGMTKADLINNLGTI
Q58FG1 T34 Sugiyama HSP90AA4P HSP90AD HSPCAL2 KEPHISLIPNKQDRtLtIVDtGIGMTKADLINNLGTITKSE
Q5VTE0 T23 Sugiyama EEF1A1P5 EEF1AL3 KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
Q5VTE0 T261 Sugiyama EEF1A1P5 EEF1AL3 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
Q5VTE0 T269 Sugiyama EEF1A1P5 EEF1AL3 PLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFAPVNVttEV
Q5VTE0 T279 Sugiyama EEF1A1P5 EEF1AL3 IGtVPVGRVEtGVLKPGMVVtFAPVNVttEVKSVEMHHEAL
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q6NXT2 T45 Sugiyama H3-5 H3F3C AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6PEY2 T334 Sugiyama TUBA3E ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q6PEY2 T41 Sugiyama TUBA3E WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q6S8J3 T789 Sugiyama POTEE A26C1A POTE2 YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71DI3 T46 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71U36 T334 Sugiyama TUBA1A TUBA3 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q71U36 T41 Sugiyama TUBA1A TUBA3 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q71UM5 S11 Sugiyama RPS27L __________MPLARDLLHPsLEEEKKKHKKKRLVQsPNsy
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7KZF4 T98 Sugiyama SND1 TDRD11 WAFPAREFLRKKLIGKEVCFtIENKtPQGREyGMIyLGKDT
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z4V5 Y18 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 ___MPHAFKPGDLVFAKMKGyPHWPARIDDIADGAVKPPPN
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86U42 S235 Sugiyama PABPN1 PAB2 PABP2 FAyIEFSDKEsVRTSLALDEsLFRGRQIKVIPKRTNRPGIS
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8IYP9 S200 Sugiyama ZDHHC23 LILLALHRAKKNPGYLSNPAsGDRSLsSSQLECLSRKGQEK
Q8N0Y7 T96 Sugiyama PGAM4 PGAM3 QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR
Q8NBT2 S16 Sugiyama SPC24 SPBC24 _____MAAFRDIEEVSQGLLsLLGANRAEAQQRRLLGRHEQ
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8WXX5 S215 Sugiyama DNAJC9 EEAKEAEMSRKELGLDEGVDsLKAAIQSRQKDRQKEMDNFL
Q92522 T55 Sugiyama H1-10 H1FX KRKNSKKKNQPGKySQLVVEtIRRLGERNGSSLAKIYTEAK
Q92598 T63 Sugiyama HSPH1 HSP105 HSP110 KIAA0201 SKNRTIGVAAKNQQITHANNtVsNFKRFHGRAFNDPFIQKE
Q92688 S117 Sugiyama ANP32B APRIL PHAPI2 GNKLKDIstLEPLKKLECLKsLDLFNCEVtNLNDyREsVFK
Q92688 T105 Sugiyama ANP32B APRIL PHAPI2 EKLPNLTHLNLsGNKLKDIstLEPLKKLECLKsLDLFNCEV
Q93045 S80 Sugiyama STMN2 SCG10 SCGN10 PPsPISEAPRTLAsPKKKDLsLEEIQKKLEAAEERRKsQEA
Q96AY3 T441 Sugiyama FKBP10 FKBP65 PSEC0056 DYGAPQEATLGANKVIEGLDtGLQGMCVGERRQLIVPPHLA
Q96QK1 T773 Sugiyama VPS35 MEM3 TCCCTA00141 DLPNLEssEEtEQINKHFHNtLEHLRLRREsPEsEGPIyEG
Q99439 T58 Sugiyama CNN2 IEGLTGLSIGPDFQKGLKDGtILCtLMNKLQPGSVPKINRS
Q99439 T62 Sugiyama CNN2 TGLSIGPDFQKGLKDGtILCtLMNKLQPGSVPKINRSMQNW
Q99613 T880 Sugiyama EIF3C EIF3S8 AEKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMR
Q99832 T458 Sugiyama CCT7 CCTH NIP7-1 yAKALEIIPRQLCDNAGFDAtNILNKLRARHAQGGTWYGVD
Q9BQE3 T334 Sugiyama TUBA1C TUBA6 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q9BQE3 T41 Sugiyama TUBA1C TUBA6 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q9BRA2 T91 Sugiyama TXNDC17 TXNL5 VGEKPYWKDPNNDFRKNLKVtAVPtLLKYGTPQKLVESECL
Q9BRA2 T95 Sugiyama TXNDC17 TXNL5 PYWKDPNNDFRKNLKVtAVPtLLKYGTPQKLVESECLQANL
Q9BS26 T155 Sugiyama ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 yIRQQKSDPIQEIRDLAEIttLDRSKRNIIGYFEQKDSDNy
Q9BUF5 T312 Sugiyama TUBB6 QMFDARNMMAACDPRHGRYLtVAtVFRGPMSMKEVDEQMLA
Q9BUF5 T315 Sugiyama TUBB6 DARNMMAACDPRHGRYLtVAtVFRGPMSMKEVDEQMLAIQS
Q9BVA1 S115 Sugiyama TUBB2B sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BVA1 T72 Sugiyama TUBB2B NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BYX7 T89 Sugiyama POTEKP ACTBL3 FKSG30 YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
Q9GZT8 T149 Sugiyama NIF3L1 ALS2CR1 MDS015 My018 AYDAAPQGVNNWLAKGLGACtSRPIHPSKAPNyPTEGNHRV
Q9H3G5 S334 Sugiyama CPVL VLP PSEC0124 UNQ197/PRO223 YYNFLRCTEPEDQLyyVKFLsLPEVRQAIHVGNQTFNDGTI
Q9H788 S124 Sugiyama SH2D4A PPP1R38 SH2A LKAEQEAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKD
Q9HA77 T546 Sugiyama CARS2 OK/SW-cl.10 CDTLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG__
Q9HB07 T49 Sugiyama MYG1 C12orf10 ESVPPPKRSRsKLMAPPRIGtHNGtFHCDEALACALLRLLP
Q9HB07 T53 Sugiyama MYG1 C12orf10 PPKRSRsKLMAPPRIGtHNGtFHCDEALACALLRLLPEYRD
Q9HB71 T209 Sugiyama CACYBP S100A6BP SIP PNAS-107 EGLMNVLKKIyEDGDDDMKRtINKAWVESREKQAKGDTEF_
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ39 T159 Sugiyama RPS10P5 RPS10L RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9NR30 T371 Sugiyama DDX21 DQVEEILSVAYKKDSEDNPQtLLFSAtCPHWVFNVAKKYMK
Q9NR30 T377 Sugiyama DDX21 LSVAYKKDSEDNPQtLLFSAtCPHWVFNVAKKYMKSTYEQV
Q9NR45 S251 Sugiyama NANS SAS GAKVLERHITLDKTWKGsDHsAsLEPGELAELVRSVRLVER
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NTJ3 T890 Sugiyama SMC4 CAPC SMC4L1 YDAVAEKAGKVEAEVKRLHNtIVEINNHKLKAQQDKLDKIN
Q9NZB2 S847 Sugiyama FAM120A C9orf10 KIAA0183 OSSA GQADQAAKVEKMRQSVLEGLsFsRQSHTLPFPPPPALPFYP
Q9P2J5 S720 Sugiyama LARS1 KIAA1352 LARS WPTAVRANGHLLLNSEKMSKstGNFLtLtQAIDKFSADGMR
Q9P2J5 T726 Sugiyama LARS1 KIAA1352 LARS ANGHLLLNSEKMSKstGNFLtLtQAIDKFSADGMRLALADA
Q9P2J5 T728 Sugiyama LARS1 KIAA1352 LARS GHLLLNSEKMSKstGNFLtLtQAIDKFSADGMRLALADAGD
Q9UBQ5 T28 Sugiyama EIF3K EIF3S12 ARG134 HSPC029 MSTP001 PTD001 RANVGKLLKGIDRyNPENLAtLERYVETQAKENAyDLEANL
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UNX3 T93 Sugiyama RPL26L1 RPL26P1 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
Q9UNZ2 S192 Sugiyama NSFL1C UBXN2C KRQHssQDVHVVLKLWKsGFsLDNGELRSyQDPsNAQFLEs
Q9Y2B0 T132 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDELIEFF
Q9Y2T7 T143 Sugiyama YBX2 CSDA3 MSY2 QtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEATNVTGP
Q9Y3E1 Y22 Sugiyama HDGFL3 HDGF2 HDGFRP3 CGI-142 ARPRPREYKAGDLVFAKMKGyPHWPARIDELPEGAVKPPAN
Q9Y3F4 S230 Sugiyama STRAP MAWD UNRIP SAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLyKy
Q9Y3F4 T225 Sugiyama STRAP MAWD UNRIP SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF
Q9Y3F4 T54 Sugiyama STRAP MAWD UNRIP SACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLNKDATKA
Q9Y3U8 S91 Sugiyama RPL36 KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y4K4 S28 Sugiyama MAP4K5 AADILRRNPQQDyELVQRVGsGTYGDVYKARNVHtGELAAV
Q9Y4K4 S413 Sugiyama MAP4K5 PPKPRIssyPEDNFPDEEKAsTIKHCPDsEsRAPQILRRQs
Q9Y4K4 S421 Sugiyama MAP4K5 yPEDNFPDEEKAsTIKHCPDsEsRAPQILRRQssPsCGPVA
Q9Y4K4 S423 Sugiyama MAP4K5 EDNFPDEEKAsTIKHCPDsEsRAPQILRRQssPsCGPVAET
Q9Y4K4 S60 Sugiyama MAP4K5 VHtGELAAVKIIKLEPGDDFsLIQQEIFMVKECKHCNIVAY
Q9Y4K4 S764 Sugiyama MAP4K5 DKFVKIVNLQGKLKSSKKLAsELSFDFRIESVVCLQDSVLA
Q9Y4K4 T304 Sugiyama MAP4K5 RALAVELLDKVNNPDNHAHytEADDDDFEPHAIIRHTIRST
Q9Y4K4 T42 Sugiyama MAP4K5 LVQRVGsGTYGDVYKARNVHtGELAAVKIIKLEPGDDFsLI
Q9Y4K4 T801 Sugiyama MAP4K5 SVLAFWKHGMQGKSFKSDEVtQEISDEtRVFRLLGSDRVVV
Q9Y4K4 T808 Sugiyama MAP4K5 HGMQGKSFKSDEVtQEISDEtRVFRLLGSDRVVVLESRPtE
Q9Y4K4 T827 Sugiyama MAP4K5 EtRVFRLLGSDRVVVLESRPtENPtAHSNLYILAGHENsY_
Q9Y4K4 T831 Sugiyama MAP4K5 FRLLGSDRVVVLESRPtENPtAHSNLYILAGHENsY_____
Q9Y4K4 Y20 Sugiyama MAP4K5 _MEAPLRPAADILRRNPQQDyELVQRVGsGTYGDVYKARNV
Q9Y4L1 S742 Sugiyama HYOU1 GRP170 HSPH4 ORP150 KLQDLTLRDLEKQEREKAANsLEAFIFEtQDKLyQPEyQEV
Q9Y4L1 T750 Sugiyama HYOU1 GRP170 HSPH4 ORP150 DLEKQEREKAANsLEAFIFEtQDKLyQPEyQEVsTEEQREE
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Axon guidance R-HSA-422475 7.881964e-07 6.103 0 0
Nervous system development R-HSA-9675108 1.962787e-06 5.707 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 3.491593e-06 5.457 0 0
Signal Transduction R-HSA-162582 5.488808e-06 5.261 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 5.513451e-06 5.259 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.658735e-05 4.780 0 0
Signaling by VEGF R-HSA-194138 1.623559e-05 4.790 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.468825e-05 4.608 0 0
Apoptotic execution phase R-HSA-75153 7.046296e-05 4.152 0 0
Signaling by ERBB2 R-HSA-1227986 1.019105e-04 3.992 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.567591e-04 3.805 0 0
Signaling by Hippo R-HSA-2028269 2.692021e-04 3.570 0 0
Signaling by PTK6 R-HSA-8848021 6.059662e-04 3.218 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 6.059662e-04 3.218 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 8.030170e-04 3.095 0 0
L1CAM interactions R-HSA-373760 7.839472e-04 3.106 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 1.013798e-03 2.994 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.019304e-03 2.992 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.332878e-03 2.875 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.577688e-03 2.802 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.915166e-03 2.718 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.989953e-03 2.701 0 0
Interaction between L1 and Ankyrins R-HSA-445095 2.141790e-03 2.669 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.097425e-03 2.678 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 2.857017e-03 2.544 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.275237e-03 2.485 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.275237e-03 2.485 0 0
MAPK family signaling cascades R-HSA-5683057 3.295373e-03 2.482 0 0
Interleukin-37 signaling R-HSA-9008059 3.275237e-03 2.485 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.051198e-03 2.392 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.994115e-03 2.399 0 0
Programmed Cell Death R-HSA-5357801 4.065860e-03 2.391 0 0
Nuclear Envelope Breakdown R-HSA-2980766 4.637735e-03 2.334 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 4.804590e-03 2.318 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 4.921172e-03 2.308 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 5.415015e-03 2.266 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 5.301616e-03 2.276 0 0
Centrosome maturation R-HSA-380287 6.173214e-03 2.209 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 6.844729e-03 2.165 0 0
Cell-extracellular matrix interactions R-HSA-446353 7.068190e-03 2.151 0 0
Sema4D in semaphorin signaling R-HSA-400685 8.063950e-03 2.093 0 0
RET signaling R-HSA-8853659 7.586415e-03 2.120 0 0
EPH-Ephrin signaling R-HSA-2682334 7.883248e-03 2.103 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 8.297049e-03 2.081 0 0
Signaling by ALK in cancer R-HSA-9700206 8.297049e-03 2.081 0 0
Interleukin-1 family signaling R-HSA-446652 8.315232e-03 2.080 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 8.994994e-03 2.046 0 0
TRP channels R-HSA-3295583 9.159101e-03 2.038 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 9.662601e-03 2.015 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.927487e-03 2.003 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.032453e-02 1.986 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.032453e-02 1.986 0 0
Intracellular signaling by second messengers R-HSA-9006925 9.965503e-03 2.002 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 9.927487e-03 2.003 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.105863e-02 1.956 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.137544e-02 1.944 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.123908e-02 1.949 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.160156e-02 1.935 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.228692e-02 1.911 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.190378e-02 1.924 0 0
Apoptosis R-HSA-109581 1.309443e-02 1.883 0 0
Ephrin signaling R-HSA-3928664 1.344683e-02 1.871 0 0
Signal attenuation R-HSA-74749 1.506413e-02 1.822 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.456211e-02 1.837 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.585960e-02 1.800 0 0
Regulation of CDH11 function R-HSA-9762292 1.506413e-02 1.822 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.488334e-02 1.827 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.421207e-02 1.847 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.363922e-02 1.626 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.363922e-02 1.626 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.363922e-02 1.626 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 2.363922e-02 1.626 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 2.363922e-02 1.626 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.618682e-02 1.791 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.618682e-02 1.791 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.978820e-02 1.704 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 2.177070e-02 1.662 0 0
RAF activation R-HSA-5673000 2.387796e-02 1.622 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.091742e-02 1.679 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.091742e-02 1.679 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.091742e-02 1.679 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.340873e-02 1.631 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.340873e-02 1.631 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.387796e-02 1.622 0 0
Signaling by RAS mutants R-HSA-6802949 2.091742e-02 1.679 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.767234e-02 1.753 0 0
Leishmania phagocytosis R-HSA-9664417 2.313867e-02 1.636 0 0
Parasite infection R-HSA-9664407 2.313867e-02 1.636 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 2.313867e-02 1.636 0 0
Mitophagy R-HSA-5205647 2.387796e-02 1.622 0 0
Interleukin-2 signaling R-HSA-9020558 1.828675e-02 1.738 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.363922e-02 1.626 0 0
Mitotic Prophase R-HSA-68875 1.838804e-02 1.735 0 0
Kinesins R-HSA-983189 1.907303e-02 1.720 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 2.406921e-02 1.619 0 0
Leishmania infection R-HSA-9658195 1.720481e-02 1.764 0 0
Parasitic Infection Pathways R-HSA-9824443 1.720481e-02 1.764 0 0
MyD88-independent TLR4 cascade R-HSA-166166 2.406921e-02 1.619 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.873521e-02 1.727 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 2.177070e-02 1.662 0 0
Muscle contraction R-HSA-397014 2.298097e-02 1.639 0 0
Cell Cycle, Mitotic R-HSA-69278 1.689437e-02 1.772 0 0
Toll-like Receptor Cascades R-HSA-168898 2.072466e-02 1.684 0 0
Semaphorin interactions R-HSA-373755 2.340873e-02 1.631 0 0
Nuclear import of Rev protein R-HSA-180746 2.387796e-02 1.622 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 2.264097e-02 1.645 0 0
Sensory processing of sound R-HSA-9659379 2.305192e-02 1.637 0 0
Signaling by Interleukins R-HSA-449147 2.377222e-02 1.624 0 0
Interleukin-12 signaling R-HSA-9020591 1.921647e-02 1.716 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 2.413502e-02 1.617 0 0
IGF1R signaling cascade R-HSA-2428924 2.499329e-02 1.602 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 2.579103e-02 1.589 0 0
Signaling by LTK R-HSA-9842663 2.579103e-02 1.589 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.611235e-02 1.583 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.612571e-02 1.583 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.664981e-02 1.574 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 2.664981e-02 1.574 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.838043e-02 1.547 0 0
AURKA Activation by TPX2 R-HSA-8854518 2.837957e-02 1.547 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.739652e-02 1.562 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 3.019403e-02 1.520 0 0
M Phase R-HSA-68886 3.062508e-02 1.514 0 0
Immune System R-HSA-168256 3.067293e-02 1.513 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 3.136587e-02 1.504 0 0
IRS activation R-HSA-74713 3.136587e-02 1.504 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 3.154542e-02 1.501 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 3.097102e-02 1.509 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 3.097102e-02 1.509 0 0
Regulated Necrosis R-HSA-5218859 3.206365e-02 1.494 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 3.097102e-02 1.509 0 0
Regulation of KIT signaling R-HSA-1433559 3.470483e-02 1.460 0 0
Cardiac conduction R-HSA-5576891 3.281624e-02 1.484 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 3.136587e-02 1.504 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.359896e-02 1.474 0 0
Long-term potentiation R-HSA-9620244 3.490945e-02 1.457 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 3.842860e-02 1.415 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 3.994014e-02 1.399 0 0
Signaling by EGFR R-HSA-177929 4.221398e-02 1.375 0 0
Signaling by FGFR1 R-HSA-5654736 4.221398e-02 1.375 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 3.994014e-02 1.399 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 4.157693e-02 1.381 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 3.847353e-02 1.415 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 3.950048e-02 1.403 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 3.950048e-02 1.403 0 0
Interleukin-2 family signaling R-HSA-451927 3.925953e-02 1.406 0 0
Diseases of programmed cell death R-HSA-9645723 3.966617e-02 1.402 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 3.994014e-02 1.399 0 0
NRAGE signals death through JNK R-HSA-193648 4.221398e-02 1.375 0 0
Post NMDA receptor activation events R-HSA-438064 3.772255e-02 1.423 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.925953e-02 1.406 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.925953e-02 1.406 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 3.994014e-02 1.399 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.787133e-02 1.422 0 0
Interleukin-12 family signaling R-HSA-447115 3.772255e-02 1.423 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 4.223814e-02 1.374 0 0
PKMTs methylate histone lysines R-HSA-3214841 4.229447e-02 1.374 0 0
FLT3 Signaling R-HSA-9607240 4.229447e-02 1.374 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 4.229447e-02 1.374 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 4.229447e-02 1.374 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 4.500229e-02 1.347 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.036843e-02 1.298 0 0
MAP2K and MAPK activation R-HSA-5674135 4.546701e-02 1.342 0 0
Signaling by ERBB4 R-HSA-1236394 4.498850e-02 1.347 0 0
Signaling by RAF1 mutants R-HSA-9656223 4.546701e-02 1.342 0 0
Killing mechanisms R-HSA-9664420 4.500229e-02 1.347 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 4.500229e-02 1.347 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 4.649785e-02 1.333 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 5.036843e-02 1.298 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 4.467540e-02 1.350 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 4.467540e-02 1.350 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 5.036843e-02 1.298 0 0
Nef and signal transduction R-HSA-164944 4.928568e-02 1.307 0 0
Cell Cycle R-HSA-1640170 4.815672e-02 1.317 0 0
Cell junction organization R-HSA-446728 4.976776e-02 1.303 0 0
MHC class II antigen presentation R-HSA-2132295 4.649785e-02 1.333 0 0
Cell-Cell communication R-HSA-1500931 4.557087e-02 1.341 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 4.928568e-02 1.307 0 0
Stimuli-sensing channels R-HSA-2672351 4.971317e-02 1.304 0 0
snRNP Assembly R-HSA-191859 5.055536e-02 1.296 0 0
Metabolism of non-coding RNA R-HSA-194441 5.055536e-02 1.296 0 0
Cytokine Signaling in Immune system R-HSA-1280215 5.062355e-02 1.296 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.065587e-02 1.295 0 0
Signaling by FGFR4 R-HSA-5654743 5.222708e-02 1.282 0 0
Signaling by SCF-KIT R-HSA-1433557 5.222708e-02 1.282 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 5.386967e-02 1.269 0 0
Netrin-1 signaling R-HSA-373752 5.581513e-02 1.253 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 5.933075e-02 1.227 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.933075e-02 1.227 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 6.293511e-02 1.201 0 0
EGFR downregulation R-HSA-182971 5.929471e-02 1.227 0 0
Diseases of mitotic cell cycle R-HSA-9675126 6.405266e-02 1.193 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 5.663629e-02 1.247 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 5.663629e-02 1.247 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 5.763202e-02 1.239 0 0
Signaling by FGFR3 R-HSA-5654741 5.954186e-02 1.225 0 0
Recycling pathway of L1 R-HSA-437239 6.741012e-02 1.171 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 6.293511e-02 1.201 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 6.281360e-02 1.202 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 5.929471e-02 1.227 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 5.954186e-02 1.225 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 6.741012e-02 1.171 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 6.293511e-02 1.201 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 6.085678e-02 1.216 0 0
tRNA processing in the nucleus R-HSA-6784531 5.983822e-02 1.223 0 0
MECP2 regulates transcription factors R-HSA-9022707 5.933075e-02 1.227 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 6.340702e-02 1.198 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 6.827690e-02 1.166 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 6.827690e-02 1.166 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 6.827690e-02 1.166 0 0
Regulation of necroptotic cell death R-HSA-5675482 6.900441e-02 1.161 0 0
Integrin signaling R-HSA-354192 6.900441e-02 1.161 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 6.900441e-02 1.161 0 0
Regulation of signaling by CBL R-HSA-912631 6.954308e-02 1.158 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 6.989296e-02 1.156 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 7.000797e-02 1.155 0 0
FGFR1b ligand binding and activation R-HSA-190370 7.000797e-02 1.155 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 7.000797e-02 1.155 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 7.000797e-02 1.155 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 7.000797e-02 1.155 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 7.155050e-02 1.145 0 0
GPER1 signaling R-HSA-9634597 7.155050e-02 1.145 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 7.538270e-02 1.123 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 7.538270e-02 1.123 0 0
Diseases of Telomere Maintenance R-HSA-9673013 7.538270e-02 1.123 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 7.538270e-02 1.123 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 7.538270e-02 1.123 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 7.538270e-02 1.123 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 7.538270e-02 1.123 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 7.538270e-02 1.123 0 0
WNT mediated activation of DVL R-HSA-201688 8.125410e-02 1.090 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 8.364619e-02 1.078 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 8.364619e-02 1.078 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 9.111985e-02 1.040 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.111985e-02 1.040 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 9.036085e-02 1.044 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 8.364619e-02 1.078 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 8.364619e-02 1.078 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 9.111985e-02 1.040 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 7.414739e-02 1.130 0 0
Inhibition of PKR R-HSA-169131 7.538270e-02 1.123 0 0
Signalling to ERKs R-HSA-187687 8.499519e-02 1.071 0 0
Ub-specific processing proteases R-HSA-5689880 7.939516e-02 1.100 0 0
Oncogene Induced Senescence R-HSA-2559585 8.499519e-02 1.071 0 0
Membrane Trafficking R-HSA-199991 7.711868e-02 1.113 0 0
Death Receptor Signaling R-HSA-73887 7.998398e-02 1.097 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 8.125410e-02 1.090 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 7.312191e-02 1.136 0 0
Cellular response to heat stress R-HSA-3371556 8.780293e-02 1.056 0 0
Interleukin-1 signaling R-HSA-9020702 7.700304e-02 1.113 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 9.111985e-02 1.040 0 0
Signal transduction by L1 R-HSA-445144 7.645027e-02 1.117 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 8.005367e-02 1.097 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.111985e-02 1.040 0 0
Folding of actin by CCT/TriC R-HSA-390450 9.300980e-02 1.031 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 9.300980e-02 1.031 0 0
Receptor Mediated Mitophagy R-HSA-8934903 9.300980e-02 1.031 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 9.300980e-02 1.031 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 9.300980e-02 1.031 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 9.300980e-02 1.031 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 9.446648e-02 1.025 0 0
Cellular Senescence R-HSA-2559583 9.655938e-02 1.015 0 0
Voltage gated Potassium channels R-HSA-1296072 9.656918e-02 1.015 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 9.760573e-02 1.011 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 9.784433e-02 1.009 0 0
mTORC1-mediated signalling R-HSA-166208 9.885987e-02 1.005 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 9.885987e-02 1.005 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.019494e-01 0.992 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.026188e-01 0.989 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.033855e-01 0.986 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.052194e-01 0.978 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.052194e-01 0.978 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 1.109188e-01 0.955 0 0
XAV939 stabilizes AXIN R-HSA-5545619 1.109188e-01 0.955 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5660724 1.109188e-01 0.955 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5619081 1.109188e-01 0.955 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.450912e-01 0.838 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.450912e-01 0.838 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.450912e-01 0.838 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.450912e-01 0.838 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.450912e-01 0.838 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.450912e-01 0.838 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.450912e-01 0.838 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.450912e-01 0.838 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.450912e-01 0.838 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.450912e-01 0.838 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.450912e-01 0.838 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.779521e-01 0.750 0 0
Classical Kir channels R-HSA-1296053 1.779521e-01 0.750 0 0
Defective GCLC causes HAGGSD R-HSA-5578999 1.779521e-01 0.750 0 0
Nucleotide catabolism defects R-HSA-9735786 2.095519e-01 0.679 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 2.095519e-01 0.679 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.095519e-01 0.679 0 0
Signaling by MAP2K mutants R-HSA-9652169 2.095519e-01 0.679 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.095519e-01 0.679 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 2.095519e-01 0.679 0 0
Activation of AMPA receptors R-HSA-399710 2.399388e-01 0.620 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 2.399388e-01 0.620 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.399388e-01 0.620 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 2.399388e-01 0.620 0 0
Defective SLC1A3 causes episodic ataxia 6 (EA6) R-HSA-5619062 2.399388e-01 0.620 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 1.178309e-01 0.929 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.178309e-01 0.929 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.178309e-01 0.929 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.307954e-01 0.883 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.691594e-01 0.570 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 2.691594e-01 0.570 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.691594e-01 0.570 0 0
Phase 1 - inactivation of fast Na+ channels R-HSA-5576894 2.691594e-01 0.570 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.576039e-01 0.802 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.972582e-01 0.527 0 0
STAT5 Activation R-HSA-9645135 2.972582e-01 0.527 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.972582e-01 0.527 0 0
Erythropoietin activates RAS R-HSA-9027284 1.713654e-01 0.766 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.713654e-01 0.766 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.713654e-01 0.766 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.713654e-01 0.766 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 1.150919e-01 0.939 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.853145e-01 0.732 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.242784e-01 0.489 0 0
SOS-mediated signalling R-HSA-112412 3.242784e-01 0.489 0 0
FGFR3b ligand binding and activation R-HSA-190371 3.242784e-01 0.489 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 3.242784e-01 0.489 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 1.994167e-01 0.700 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 1.411379e-01 0.850 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.136395e-01 0.670 0 0
Type I hemidesmosome assembly R-HSA-446107 3.502613e-01 0.456 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.502613e-01 0.456 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 3.502613e-01 0.456 0 0
Formation of annular gap junctions R-HSA-196025 3.502613e-01 0.456 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 2.279531e-01 0.642 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.279531e-01 0.642 0 0
PKA activation in glucagon signalling R-HSA-164378 2.279531e-01 0.642 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.152219e-01 0.938 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.689261e-01 0.772 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.752466e-01 0.426 0 0
Gap junction degradation R-HSA-190873 3.752466e-01 0.426 0 0
CASP8 activity is inhibited R-HSA-5218900 3.752466e-01 0.426 0 0
ALK mutants bind TKIs R-HSA-9700645 3.752466e-01 0.426 0 0
Trafficking of AMPA receptors R-HSA-399719 1.785185e-01 0.748 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.981256e-01 0.703 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 2.711684e-01 0.567 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.711684e-01 0.567 0 0
MAPK3 (ERK1) activation R-HSA-110056 3.992725e-01 0.399 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.992725e-01 0.399 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 2.855849e-01 0.544 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 2.999714e-01 0.523 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.223759e-01 0.374 0 0
Deadenylation of mRNA R-HSA-429947 3.285803e-01 0.483 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 3.285803e-01 0.483 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 2.190103e-01 0.660 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.670004e-01 0.777 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.670004e-01 0.777 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 3.708416e-01 0.431 0 0
Signaling by Erythropoietin R-HSA-9006335 3.984235e-01 0.400 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 3.742357e-01 0.427 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 3.114015e-01 0.507 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 3.114015e-01 0.507 0 0
mRNA 3'-end processing R-HSA-72187 4.176412e-01 0.379 0 0
Signaling by EGFR in Cancer R-HSA-1643713 1.322459e-01 0.879 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 2.284161e-01 0.641 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 1.594903e-01 0.797 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 1.689261e-01 0.772 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 2.284161e-01 0.641 0 0
DAP12 signaling R-HSA-2424491 4.120030e-01 0.385 0 0
mRNA Splicing R-HSA-72172 3.830950e-01 0.417 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 3.114015e-01 0.507 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.711684e-01 0.567 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.337214e-01 0.874 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.266225e-01 0.486 0 0
Neutrophil degranulation R-HSA-6798695 1.858265e-01 0.731 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.257834e-01 0.900 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.178309e-01 0.929 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 1.994167e-01 0.700 0 0
Signaling by FGFR R-HSA-190236 1.401053e-01 0.854 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.279531e-01 0.642 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.494772e-01 0.825 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 3.742357e-01 0.427 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 1.785185e-01 0.748 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.782918e-01 0.749 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 4.089015e-01 0.388 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 2.182172e-01 0.661 0 0
Signaling by FGFR2 R-HSA-5654738 1.350798e-01 0.869 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 2.136395e-01 0.670 0 0
PI3K/AKT activation R-HSA-198203 3.992725e-01 0.399 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 4.223759e-01 0.374 0 0
Activation of the pre-replicative complex R-HSA-68962 4.120030e-01 0.385 0 0
Insulin receptor signalling cascade R-HSA-74751 1.552464e-01 0.809 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.502235e-01 0.823 0 0
PKA activation R-HSA-163615 2.279531e-01 0.642 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 2.006684e-01 0.698 0 0
Regulation of mitotic cell cycle R-HSA-453276 2.006684e-01 0.698 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 3.937088e-01 0.405 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.567123e-01 0.805 0 0
Signaling by Insulin receptor R-HSA-74752 3.705539e-01 0.431 0 0
DNA Double Strand Break Response R-HSA-5693606 1.741674e-01 0.759 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.863810e-01 0.413 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 2.711684e-01 0.567 0 0
Signalling to RAS R-HSA-167044 2.711684e-01 0.567 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.910755e-01 0.536 0 0
Signaling by FGFR1 in disease R-HSA-5655302 3.016694e-01 0.520 0 0
TNF signaling R-HSA-75893 1.094748e-01 0.961 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.565446e-01 0.448 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 2.399388e-01 0.620 0 0
FGFR1c ligand binding and activation R-HSA-190373 1.440673e-01 0.841 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 1.994167e-01 0.700 0 0
FGFR2b ligand binding and activation R-HSA-190377 4.223759e-01 0.374 0 0
Defective pyroptosis R-HSA-9710421 3.229025e-01 0.491 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 3.478449e-01 0.459 0 0
Adipogenesis R-HSA-9843745 3.550701e-01 0.450 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 2.200449e-01 0.657 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 3.623793e-01 0.441 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 3.730020e-01 0.428 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.713654e-01 0.766 0 0
HSF1-dependent transactivation R-HSA-3371571 2.028245e-01 0.693 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 3.830182e-01 0.417 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 2.779622e-01 0.556 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 2.779622e-01 0.556 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 2.779622e-01 0.556 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 2.779622e-01 0.556 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 3.568607e-01 0.448 0 0
Regulation of TNFR1 signaling R-HSA-5357905 1.641093e-01 0.785 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 2.095519e-01 0.679 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.691594e-01 0.570 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 2.691594e-01 0.570 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 1.713654e-01 0.766 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 2.136395e-01 0.670 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.752466e-01 0.426 0 0
Clathrin-mediated endocytosis R-HSA-8856828 1.057454e-01 0.976 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 1.235597e-01 0.908 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 2.866010e-01 0.543 0 0
Homology Directed Repair R-HSA-5693538 2.629270e-01 0.580 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 1.310290e-01 0.883 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.502235e-01 0.823 0 0
FGFR1 ligand binding and activation R-HSA-190242 2.279531e-01 0.642 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 1.594903e-01 0.797 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 2.182172e-01 0.661 0 0
Protein folding R-HSA-391251 2.138855e-01 0.670 0 0
FGFR1 mutant receptor activation R-HSA-1839124 1.981256e-01 0.703 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.752466e-01 0.426 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 2.855849e-01 0.544 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 3.708416e-01 0.431 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.302592e-01 0.481 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 1.981256e-01 0.703 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 3.568607e-01 0.448 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 3.300676e-01 0.481 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.322279e-01 0.879 0 0
G-protein mediated events R-HSA-112040 1.741674e-01 0.759 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 1.109188e-01 0.955 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.109188e-01 0.955 0 0
Reelin signalling pathway R-HSA-8866376 2.399388e-01 0.620 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.440673e-01 0.841 0 0
G2/M DNA replication checkpoint R-HSA-69478 2.972582e-01 0.527 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 1.853145e-01 0.732 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.242784e-01 0.489 0 0
Myogenesis R-HSA-525793 1.322459e-01 0.879 0 0
Regulation by c-FLIP R-HSA-3371378 3.502613e-01 0.456 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 1.502235e-01 0.823 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 3.752466e-01 0.426 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 3.992725e-01 0.399 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 3.992725e-01 0.399 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 3.992725e-01 0.399 0 0
Notch-HLH transcription pathway R-HSA-350054 2.999714e-01 0.523 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 2.387023e-01 0.622 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.143091e-01 0.503 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.179882e-01 0.928 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 3.122812e-01 0.505 0 0
Neurexins and neuroligins R-HSA-6794361 4.176412e-01 0.379 0 0
Mismatch Repair R-HSA-5358508 2.279531e-01 0.642 0 0
Cyclin D associated events in G1 R-HSA-69231 1.494439e-01 0.826 0 0
G1 Phase R-HSA-69236 1.494439e-01 0.826 0 0
Frs2-mediated activation R-HSA-170968 1.440673e-01 0.841 0 0
Signaling by NOTCH1 R-HSA-1980143 2.355350e-01 0.628 0 0
Spry regulation of FGF signaling R-HSA-1295596 1.713654e-01 0.766 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.661046e-01 0.436 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 3.242784e-01 0.489 0 0
Effects of PIP2 hydrolysis R-HSA-114508 2.081166e-01 0.682 0 0
Termination of translesion DNA synthesis R-HSA-5656169 3.984235e-01 0.400 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 4.048667e-01 0.393 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 2.779622e-01 0.556 0 0
Signaling by NOTCH R-HSA-157118 3.240435e-01 0.489 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.399388e-01 0.620 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 3.502613e-01 0.456 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 2.805087e-01 0.552 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 2.805087e-01 0.552 0 0
Prolonged ERK activation events R-HSA-169893 1.853145e-01 0.732 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 3.830182e-01 0.417 0 0
Negative regulation of MET activity R-HSA-6807004 2.567425e-01 0.591 0 0
Ion homeostasis R-HSA-5578775 1.094748e-01 0.961 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.016694e-01 0.520 0 0
Mitotic Anaphase R-HSA-68882 1.413863e-01 0.850 0 0
FLT3 signaling in disease R-HSA-9682385 2.387023e-01 0.622 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 3.242784e-01 0.489 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 3.752466e-01 0.426 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.992725e-01 0.399 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.444846e-01 0.840 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 3.929443e-01 0.406 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 2.182172e-01 0.661 0 0
Regulation of BACH1 activity R-HSA-9708530 1.853145e-01 0.732 0 0
Pyroptosis R-HSA-5620971 1.502235e-01 0.823 0 0
PLC beta mediated events R-HSA-112043 1.372400e-01 0.863 0 0
Smooth Muscle Contraction R-HSA-445355 2.190103e-01 0.660 0 0
Platelet calcium homeostasis R-HSA-418360 3.984235e-01 0.400 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.423293e-01 0.616 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.150919e-01 0.939 0 0
Mitotic Prometaphase R-HSA-68877 1.339338e-01 0.873 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 1.152219e-01 0.938 0 0
Diseases of Immune System R-HSA-5260271 1.152219e-01 0.938 0 0
DAG and IP3 signaling R-HSA-1489509 1.567123e-01 0.805 0 0
Selective autophagy R-HSA-9663891 1.840505e-01 0.735 0 0
Interleukin-15 signaling R-HSA-8983432 1.307954e-01 0.883 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.251407e-01 0.903 0 0
Innate Immune System R-HSA-168249 1.709262e-01 0.767 0 0
MTOR signalling R-HSA-165159 1.353151e-01 0.869 0 0
Breakdown of the nuclear lamina R-HSA-352238 1.109188e-01 0.955 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.779521e-01 0.750 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 2.095519e-01 0.679 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.691594e-01 0.570 0 0
Negative regulation of FLT3 R-HSA-9706369 1.853145e-01 0.732 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.242784e-01 0.489 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.242784e-01 0.489 0 0
Tight junction interactions R-HSA-420029 1.235597e-01 0.908 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 3.502613e-01 0.456 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 3.502613e-01 0.456 0 0
Dimerization of procaspase-8 R-HSA-69416 3.502613e-01 0.456 0 0
TGFBR3 PTM regulation R-HSA-9839383 3.502613e-01 0.456 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.279531e-01 0.642 0 0
ARMS-mediated activation R-HSA-170984 3.752466e-01 0.426 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.182172e-01 0.661 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.372400e-01 0.863 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 2.699782e-01 0.569 0 0
Protein-protein interactions at synapses R-HSA-6794362 1.614719e-01 0.792 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 2.805087e-01 0.552 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 3.863810e-01 0.413 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.939167e-01 0.712 0 0
Vesicle-mediated transport R-HSA-5653656 4.172556e-01 0.380 0 0
Calmodulin induced events R-HSA-111933 2.387023e-01 0.622 0 0
Degradation of CDH1 R-HSA-9766229 3.863810e-01 0.413 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 2.017521e-01 0.695 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 3.568607e-01 0.448 0 0
CaM pathway R-HSA-111997 2.387023e-01 0.622 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 2.972582e-01 0.527 0 0
Rap1 signalling R-HSA-392517 2.423293e-01 0.616 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.752466e-01 0.426 0 0
Triglyceride biosynthesis R-HSA-75109 3.708416e-01 0.431 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 3.682233e-01 0.434 0 0
Signaling by ROBO receptors R-HSA-376176 2.579546e-01 0.588 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.619097e-01 0.582 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.844678e-01 0.546 0 0
Cell-cell junction organization R-HSA-421270 2.692075e-01 0.570 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 1.853145e-01 0.732 0 0
EPHB-mediated forward signaling R-HSA-3928662 3.335247e-01 0.477 0 0
DNA Damage Bypass R-HSA-73893 3.863810e-01 0.413 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 1.293616e-01 0.888 0 0
Signaling by TGFBR3 R-HSA-9839373 3.547404e-01 0.450 0 0
Ca-dependent events R-HSA-111996 3.122812e-01 0.505 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.350798e-01 0.869 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.809070e-01 0.743 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.069982e-01 0.971 0 0
Cellular responses to stress R-HSA-2262752 1.733301e-01 0.761 0 0
Co-inhibition by BTLA R-HSA-9927353 2.399388e-01 0.620 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.399388e-01 0.620 0 0
Activation of RAC1 R-HSA-428540 1.178309e-01 0.929 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.691594e-01 0.570 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.242784e-01 0.489 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 3.242784e-01 0.489 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 3.242784e-01 0.489 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 3.502613e-01 0.456 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 3.752466e-01 0.426 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 3.752466e-01 0.426 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 3.122812e-01 0.505 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 3.846996e-01 0.415 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.005361e-01 0.397 0 0
Deubiquitination R-HSA-5688426 1.282604e-01 0.892 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 3.708416e-01 0.431 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 3.568607e-01 0.448 0 0
Cellular responses to stimuli R-HSA-8953897 1.480446e-01 0.830 0 0
Neurodegenerative Diseases R-HSA-8863678 1.150919e-01 0.939 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.150919e-01 0.939 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 3.300131e-01 0.481 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 1.221322e-01 0.913 0 0
HDL assembly R-HSA-8963896 1.576039e-01 0.802 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 1.341843e-01 0.872 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 2.910755e-01 0.536 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 2.844678e-01 0.546 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.855849e-01 0.544 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.411379e-01 0.850 0 0
Neuronal System R-HSA-112316 1.567327e-01 0.805 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.399388e-01 0.620 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 2.691594e-01 0.570 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 2.691594e-01 0.570 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 1.440673e-01 0.841 0 0
Synthesis of PG R-HSA-1483148 1.994167e-01 0.700 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.752466e-01 0.426 0 0
Interleukin-1 processing R-HSA-448706 3.752466e-01 0.426 0 0
Signaling by NOTCH4 R-HSA-9013694 1.063928e-01 0.973 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.223759e-01 0.374 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 4.223759e-01 0.374 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 3.018400e-01 0.520 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.385985e-01 0.470 0 0
Potassium Channels R-HSA-1296071 4.089015e-01 0.388 0 0
Transmission across Chemical Synapses R-HSA-112315 3.698525e-01 0.432 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.690691e-01 0.772 0 0
Cell Cycle Checkpoints R-HSA-69620 2.986565e-01 0.525 0 0
Signaling by NOTCH3 R-HSA-9012852 2.355265e-01 0.628 0 0
Signaling by NTRKs R-HSA-166520 2.080672e-01 0.682 0 0
G2/M Transition R-HSA-69275 1.861356e-01 0.730 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.940681e-01 0.712 0 0
Adaptive Immune System R-HSA-1280218 2.233937e-01 0.651 0 0
Glycolysis R-HSA-70171 1.494772e-01 0.825 0 0
Inositol phosphate metabolism R-HSA-1483249 2.168719e-01 0.664 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.853145e-01 0.732 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 2.108732e-01 0.676 0 0
PI3K Cascade R-HSA-109704 3.968516e-01 0.401 0 0
Regulation of TP53 Activity R-HSA-5633007 1.658394e-01 0.780 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 2.281086e-01 0.642 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.742357e-01 0.427 0 0
FOXO-mediated transcription R-HSA-9614085 1.447549e-01 0.839 0 0
Influenza Infection R-HSA-168255 2.529961e-01 0.597 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 3.127236e-01 0.505 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.440673e-01 0.841 0 0
Zinc efflux and compartmentalization by the SLC30 family R-HSA-435368 2.399388e-01 0.620 0 0
Tie2 Signaling R-HSA-210993 2.279531e-01 0.642 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 3.752466e-01 0.426 0 0
PECAM1 interactions R-HSA-210990 4.223759e-01 0.374 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 2.711684e-01 0.567 0 0
G alpha (12/13) signalling events R-HSA-416482 1.251407e-01 0.903 0 0
Host Interactions of HIV factors R-HSA-162909 2.991069e-01 0.524 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 3.752466e-01 0.426 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 3.235635e-01 0.490 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.068545e-01 0.971 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.711684e-01 0.567 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 3.708416e-01 0.431 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 3.992685e-01 0.399 0 0
Growth hormone receptor signaling R-HSA-982772 3.143091e-01 0.503 0 0
Signaling by Leptin R-HSA-2586552 3.992725e-01 0.399 0 0
Plasma lipoprotein assembly R-HSA-8963898 3.285803e-01 0.483 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.708416e-01 0.431 0 0
SARS-CoV-2 Infection R-HSA-9694516 2.047960e-01 0.689 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 3.752466e-01 0.426 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.387023e-01 0.622 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.143091e-01 0.503 0 0
Glucose metabolism R-HSA-70326 2.570189e-01 0.590 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 1.440673e-01 0.841 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.758679e-01 0.425 0 0
SARS-CoV Infections R-HSA-9679506 4.086552e-01 0.389 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 2.136395e-01 0.670 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 2.699782e-01 0.569 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 1.576039e-01 0.802 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 2.423293e-01 0.616 0 0
Signaling by ALK R-HSA-201556 2.699782e-01 0.569 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.726078e-01 0.763 0 0
IRE1alpha activates chaperones R-HSA-381070 2.077871e-01 0.682 0 0
Gene Silencing by RNA R-HSA-211000 3.249275e-01 0.488 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 2.646689e-01 0.577 0 0
Post-translational protein phosphorylation R-HSA-8957275 4.241662e-01 0.372 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 4.254291e-01 0.371 0 0
Cargo concentration in the ER R-HSA-5694530 4.254291e-01 0.371 0 0
Downstream signal transduction R-HSA-186763 4.254291e-01 0.371 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.279486e-01 0.369 0 0
Meiotic synapsis R-HSA-1221632 4.279486e-01 0.369 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.279486e-01 0.369 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.279486e-01 0.369 0 0
Ion channel transport R-HSA-983712 4.285898e-01 0.368 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.349999e-01 0.362 0 0
PCP/CE pathway R-HSA-4086400 4.352751e-01 0.361 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.445922e-01 0.352 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.445922e-01 0.352 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 4.445922e-01 0.352 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.445922e-01 0.352 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.445922e-01 0.352 0 0
Plasmalogen biosynthesis R-HSA-75896 4.445922e-01 0.352 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 4.445922e-01 0.352 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 4.445922e-01 0.352 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.445922e-01 0.352 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.445922e-01 0.352 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 4.469177e-01 0.350 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 4.517887e-01 0.345 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 4.517887e-01 0.345 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 4.524383e-01 0.344 0 0
Signaling by MET R-HSA-6806834 4.524383e-01 0.344 0 0
Cellular response to chemical stress R-HSA-9711123 4.550609e-01 0.342 0 0
Formation of the cornified envelope R-HSA-6809371 4.554773e-01 0.342 0 0
Adherens junctions interactions R-HSA-418990 4.557896e-01 0.341 0 0
Processing of DNA double-strand break ends R-HSA-5693607 4.609567e-01 0.336 0 0
tRNA processing R-HSA-72306 4.619055e-01 0.335 0 0
Striated Muscle Contraction R-HSA-390522 4.647081e-01 0.333 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 4.647081e-01 0.333 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 4.647081e-01 0.333 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 4.659552e-01 0.332 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.659552e-01 0.332 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 4.659552e-01 0.332 0 0
IRAK1 recruits IKK complex R-HSA-937039 4.659552e-01 0.332 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 4.659552e-01 0.332 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.659552e-01 0.332 0 0
GRB2 events in EGFR signaling R-HSA-179812 4.659552e-01 0.332 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.659552e-01 0.332 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.659552e-01 0.332 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 4.659552e-01 0.332 0 0
MET activates RAS signaling R-HSA-8851805 4.659552e-01 0.332 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.659552e-01 0.332 0 0
Leading Strand Synthesis R-HSA-69109 4.659552e-01 0.332 0 0
Polymerase switching R-HSA-69091 4.659552e-01 0.332 0 0
Regulation of IFNG signaling R-HSA-877312 4.659552e-01 0.332 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 4.659552e-01 0.332 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 4.659552e-01 0.332 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 4.659552e-01 0.332 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 4.659552e-01 0.332 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.659552e-01 0.332 0 0
OAS antiviral response R-HSA-8983711 4.659552e-01 0.332 0 0
HCMV Early Events R-HSA-9609690 4.669299e-01 0.331 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 4.669299e-01 0.331 0 0
Regulation of CDH1 Function R-HSA-9764561 4.684766e-01 0.329 0 0
IRS-mediated signalling R-HSA-112399 4.684766e-01 0.329 0 0
Opioid Signalling R-HSA-111885 4.694364e-01 0.328 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 4.694364e-01 0.328 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 4.757765e-01 0.323 0 0
RSV-host interactions R-HSA-9833110 4.768803e-01 0.322 0 0
Signaling by NOTCH2 R-HSA-1980145 4.774460e-01 0.321 0 0
Calnexin/calreticulin cycle R-HSA-901042 4.774460e-01 0.321 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 4.778518e-01 0.321 0 0
G2/M Checkpoints R-HSA-69481 4.824954e-01 0.317 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 4.862228e-01 0.313 0 0
Adenylate cyclase activating pathway R-HSA-170660 4.864978e-01 0.313 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 4.864978e-01 0.313 0 0
FGFR2c ligand binding and activation R-HSA-190375 4.864978e-01 0.313 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 4.864978e-01 0.313 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 4.864978e-01 0.313 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 4.864978e-01 0.313 0 0
FGFR4 ligand binding and activation R-HSA-190322 4.864978e-01 0.313 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 4.864978e-01 0.313 0 0
Diseases of nucleotide metabolism R-HSA-9735804 4.864978e-01 0.313 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 4.864978e-01 0.313 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 4.864978e-01 0.313 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 4.864978e-01 0.313 0 0
FGFR3 mutant receptor activation R-HSA-2033514 4.864978e-01 0.313 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 4.864978e-01 0.313 0 0
Maturation of nucleoprotein R-HSA-9683610 4.864978e-01 0.313 0 0
Interleukin-6 signaling R-HSA-1059683 4.864978e-01 0.313 0 0
Triglyceride metabolism R-HSA-8979227 4.882563e-01 0.311 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.907701e-01 0.309 0 0
SARS-CoV-1-host interactions R-HSA-9692914 4.916620e-01 0.308 0 0
Hemostasis R-HSA-109582 4.922395e-01 0.308 0 0
RAB geranylgeranylation R-HSA-8873719 4.980111e-01 0.303 0 0
Regulation of PTEN gene transcription R-HSA-8943724 4.980111e-01 0.303 0 0
tRNA Aminoacylation R-HSA-379724 4.980111e-01 0.303 0 0
Glutathione conjugation R-HSA-156590 4.980111e-01 0.303 0 0
PRC2 methylates histones and DNA R-HSA-212300 5.023571e-01 0.299 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 5.023571e-01 0.299 0 0
GPVI-mediated activation cascade R-HSA-114604 5.023571e-01 0.299 0 0
RUNX2 regulates bone development R-HSA-8941326 5.023571e-01 0.299 0 0
DNA Replication R-HSA-69306 5.053860e-01 0.296 0 0
Removal of the Flap Intermediate R-HSA-69166 5.062515e-01 0.296 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 5.062515e-01 0.296 0 0
FGFR3c ligand binding and activation R-HSA-190372 5.062515e-01 0.296 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 5.062515e-01 0.296 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 5.062515e-01 0.296 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 5.062515e-01 0.296 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 5.062515e-01 0.296 0 0
Signal regulatory protein family interactions R-HSA-391160 5.062515e-01 0.296 0 0
Zinc transporters R-HSA-435354 5.062515e-01 0.296 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 5.062890e-01 0.296 0 0
Antigen processing-Cross presentation R-HSA-1236975 5.062890e-01 0.296 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.076713e-01 0.294 0 0
MAP kinase activation R-HSA-450294 5.076713e-01 0.294 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 5.109976e-01 0.292 0 0
Ovarian tumor domain proteases R-HSA-5689896 5.145220e-01 0.289 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.172336e-01 0.286 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 5.172336e-01 0.286 0 0
Interferon Signaling R-HSA-913531 5.174458e-01 0.286 0 0
PPARA activates gene expression R-HSA-1989781 5.175206e-01 0.286 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.252463e-01 0.280 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 5.252463e-01 0.280 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 5.252463e-01 0.280 0 0
Processive synthesis on the lagging strand R-HSA-69183 5.252463e-01 0.280 0 0
FGFR3 ligand binding and activation R-HSA-190239 5.252463e-01 0.280 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 5.252463e-01 0.280 0 0
DCC mediated attractive signaling R-HSA-418885 5.252463e-01 0.280 0 0
p38MAPK events R-HSA-171007 5.252463e-01 0.280 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 5.252463e-01 0.280 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 5.252463e-01 0.280 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 5.252463e-01 0.280 0 0
Purine salvage R-HSA-74217 5.264885e-01 0.279 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 5.295468e-01 0.276 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 5.350203e-01 0.272 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 5.350203e-01 0.272 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 5.355165e-01 0.271 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 5.382540e-01 0.269 0 0
Base Excision Repair R-HSA-73884 5.431541e-01 0.265 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.435116e-01 0.265 0 0
Phosphorylation of the APC/C R-HSA-176412 5.435116e-01 0.265 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 5.435116e-01 0.265 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.435116e-01 0.265 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.435116e-01 0.265 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.435116e-01 0.265 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 5.435116e-01 0.265 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.435116e-01 0.265 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.435116e-01 0.265 0 0
Signaling by TGFB family members R-HSA-9006936 5.473641e-01 0.262 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 5.498162e-01 0.260 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 5.498162e-01 0.260 0 0
Attenuation phase R-HSA-3371568 5.498162e-01 0.260 0 0
ESR-mediated signaling R-HSA-8939211 5.519432e-01 0.258 0 0
Integration of energy metabolism R-HSA-163685 5.543361e-01 0.256 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 5.560600e-01 0.255 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 5.588193e-01 0.253 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 5.610752e-01 0.251 0 0
Phase 2 - plateau phase R-HSA-5576893 5.610752e-01 0.251 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 5.610752e-01 0.251 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.610752e-01 0.251 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.610752e-01 0.251 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 5.610752e-01 0.251 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 5.611733e-01 0.251 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 5.611733e-01 0.251 0 0
Maturation of spike protein R-HSA-9694548 5.611733e-01 0.251 0 0
Interferon alpha/beta signaling R-HSA-909733 5.698222e-01 0.244 0 0
Separation of Sister Chromatids R-HSA-2467813 5.706648e-01 0.244 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 5.723240e-01 0.242 0 0
Intra-Golgi traffic R-HSA-6811438 5.723240e-01 0.242 0 0
PTEN Regulation R-HSA-6807070 5.731333e-01 0.242 0 0
Unfolded Protein Response (UPR) R-HSA-381119 5.731333e-01 0.242 0 0
Cilium Assembly R-HSA-5617833 5.742509e-01 0.241 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 5.779641e-01 0.238 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 5.779641e-01 0.238 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 5.779641e-01 0.238 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 5.779641e-01 0.238 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 5.779641e-01 0.238 0 0
Uptake and function of anthrax toxins R-HSA-5210891 5.779641e-01 0.238 0 0
Activation of GABAB receptors R-HSA-991365 5.832673e-01 0.234 0 0
GABA B receptor activation R-HSA-977444 5.832673e-01 0.234 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 5.832673e-01 0.234 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 5.832673e-01 0.234 0 0
Macroautophagy R-HSA-1632852 5.854451e-01 0.233 0 0
Epigenetic regulation of gene expression R-HSA-212165 5.860507e-01 0.232 0 0
SLC transporter disorders R-HSA-5619102 5.877672e-01 0.231 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 5.899010e-01 0.229 0 0
Interleukin-17 signaling R-HSA-448424 5.899010e-01 0.229 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 5.899010e-01 0.229 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 5.942041e-01 0.226 0 0
GAB1 signalosome R-HSA-180292 5.942041e-01 0.226 0 0
Activated point mutants of FGFR2 R-HSA-2033519 5.942041e-01 0.226 0 0
Presynaptic function of Kainate receptors R-HSA-500657 5.942041e-01 0.226 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 5.942041e-01 0.226 0 0
Synaptic adhesion-like molecules R-HSA-8849932 5.942041e-01 0.226 0 0
Platelet sensitization by LDL R-HSA-432142 5.942041e-01 0.226 0 0
Polo-like kinase mediated events R-HSA-156711 5.942041e-01 0.226 0 0
Apoptotic factor-mediated response R-HSA-111471 5.942041e-01 0.226 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.975724e-01 0.224 0 0
Platelet activation, signaling and aggregation R-HSA-76002 6.021587e-01 0.220 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.040040e-01 0.219 0 0
DAP12 interactions R-HSA-2172127 6.045301e-01 0.219 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 6.069315e-01 0.217 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.069315e-01 0.217 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.098201e-01 0.215 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.098201e-01 0.215 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 6.098201e-01 0.215 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 6.098201e-01 0.215 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 6.098201e-01 0.215 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.098201e-01 0.215 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.098201e-01 0.215 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.098201e-01 0.215 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 6.098201e-01 0.215 0 0
Translesion Synthesis by POLH R-HSA-110320 6.098201e-01 0.215 0 0
Maturation of nucleoprotein R-HSA-9694631 6.098201e-01 0.215 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 6.098201e-01 0.215 0 0
The NLRP3 inflammasome R-HSA-844456 6.098201e-01 0.215 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.112567e-01 0.214 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 6.148494e-01 0.211 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 6.148494e-01 0.211 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 6.148494e-01 0.211 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 6.148494e-01 0.211 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 6.148494e-01 0.211 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 6.152685e-01 0.211 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.152685e-01 0.211 0 0
Ca2+ pathway R-HSA-4086398 6.152685e-01 0.211 0 0
Regulation of insulin secretion R-HSA-422356 6.184270e-01 0.209 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 6.209222e-01 0.207 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 6.212468e-01 0.207 0 0
Signaling by FGFR in disease R-HSA-1226099 6.234854e-01 0.205 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 6.248361e-01 0.204 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 6.248361e-01 0.204 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 6.248361e-01 0.204 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 6.248361e-01 0.204 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 6.248361e-01 0.204 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 6.248361e-01 0.204 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 6.248361e-01 0.204 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 6.248361e-01 0.204 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 6.248361e-01 0.204 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 6.248361e-01 0.204 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.248361e-01 0.204 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.248361e-01 0.204 0 0
Nephrin family interactions R-HSA-373753 6.248361e-01 0.204 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 6.249611e-01 0.204 0 0
Diseases of DNA repair R-HSA-9675135 6.249611e-01 0.204 0 0
Co-inhibition by PD-1 R-HSA-389948 6.262651e-01 0.203 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 6.263041e-01 0.203 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 6.263041e-01 0.203 0 0
ER to Golgi Anterograde Transport R-HSA-199977 6.270403e-01 0.203 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 6.281315e-01 0.202 0 0
Disease R-HSA-1643685 6.322026e-01 0.199 0 0
S Phase R-HSA-69242 6.327823e-01 0.199 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 6.348660e-01 0.197 0 0
FGFR2 ligand binding and activation R-HSA-190241 6.392751e-01 0.194 0 0
Lagging Strand Synthesis R-HSA-69186 6.392751e-01 0.194 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.392751e-01 0.194 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 6.392751e-01 0.194 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 6.392751e-01 0.194 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 6.395564e-01 0.194 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 6.408550e-01 0.193 0 0
G1/S Transition R-HSA-69206 6.413013e-01 0.193 0 0
Co-stimulation by CD28 R-HSA-389356 6.445649e-01 0.191 0 0
PI Metabolism R-HSA-1483255 6.462681e-01 0.190 0 0
Translation of Structural Proteins R-HSA-9694635 6.474094e-01 0.189 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.531593e-01 0.185 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 6.531593e-01 0.185 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 6.531593e-01 0.185 0 0
Glutathione synthesis and recycling R-HSA-174403 6.531593e-01 0.185 0 0
Signaling by PDGFR in disease R-HSA-9671555 6.531593e-01 0.185 0 0
Ribavirin ADME R-HSA-9755088 6.531593e-01 0.185 0 0
Platelet degranulation R-HSA-114608 6.534744e-01 0.185 0 0
RNA Polymerase I Transcription R-HSA-73864 6.551403e-01 0.184 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 6.596753e-01 0.181 0 0
Regulation of RAS by GAPs R-HSA-5658442 6.633499e-01 0.178 0 0
Azathioprine ADME R-HSA-9748787 6.633499e-01 0.178 0 0
Chromatin modifying enzymes R-HSA-3247509 6.636358e-01 0.178 0 0
Developmental Biology R-HSA-1266738 6.653437e-01 0.177 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 6.665098e-01 0.176 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 6.665098e-01 0.176 0 0
FGFR2 alternative splicing R-HSA-6803529 6.665098e-01 0.176 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 6.665098e-01 0.176 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 6.665098e-01 0.176 0 0
LDL clearance R-HSA-8964038 6.665098e-01 0.176 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 6.665098e-01 0.176 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.665098e-01 0.176 0 0
PKR-mediated signaling R-HSA-9833482 6.702349e-01 0.174 0 0
Meiotic recombination R-HSA-912446 6.724388e-01 0.172 0 0
Autophagy R-HSA-9612973 6.768043e-01 0.170 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 6.793473e-01 0.168 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 6.793473e-01 0.168 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 6.793473e-01 0.168 0 0
Syndecan interactions R-HSA-3000170 6.793473e-01 0.168 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 6.813278e-01 0.167 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 6.813278e-01 0.167 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 6.813278e-01 0.167 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 6.813278e-01 0.167 0 0
HIV Life Cycle R-HSA-162587 6.820612e-01 0.166 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 6.848401e-01 0.164 0 0
Synthesis of DNA R-HSA-69239 6.854451e-01 0.164 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 6.900186e-01 0.161 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 6.916683e-01 0.160 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 6.916683e-01 0.160 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 6.916913e-01 0.160 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 6.916913e-01 0.160 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 6.916913e-01 0.160 0 0
Complex III assembly R-HSA-9865881 6.916913e-01 0.160 0 0
TNFs bind their physiological receptors R-HSA-5669034 6.916913e-01 0.160 0 0
Interleukin-6 family signaling R-HSA-6783589 6.916913e-01 0.160 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 6.939647e-01 0.159 0 0
DNA Replication Pre-Initiation R-HSA-69002 6.978037e-01 0.156 0 0
Translation initiation complex formation R-HSA-72649 6.985134e-01 0.156 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 6.985134e-01 0.156 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.989572e-01 0.156 0 0
Signaling by WNT R-HSA-195721 7.015401e-01 0.154 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.035609e-01 0.153 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 7.035609e-01 0.153 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 7.035609e-01 0.153 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.035609e-01 0.153 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.035609e-01 0.153 0 0
G protein gated Potassium channels R-HSA-1296059 7.035609e-01 0.153 0 0
TGFBR3 expression R-HSA-9839394 7.035609e-01 0.153 0 0
Hyaluronan degradation R-HSA-2160916 7.035609e-01 0.153 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 7.035609e-01 0.153 0 0
Acyl chain remodelling of PS R-HSA-1482801 7.035609e-01 0.153 0 0
HDMs demethylate histones R-HSA-3214842 7.035609e-01 0.153 0 0
Laminin interactions R-HSA-3000157 7.035609e-01 0.153 0 0
Interleukin-7 signaling R-HSA-1266695 7.035609e-01 0.153 0 0
Meiosis R-HSA-1500620 7.058336e-01 0.151 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 7.068144e-01 0.151 0 0
HDACs deacetylate histones R-HSA-3214815 7.068144e-01 0.151 0 0
G alpha (z) signalling events R-HSA-418597 7.068144e-01 0.151 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 7.068144e-01 0.151 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.125893e-01 0.147 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 7.125893e-01 0.147 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 7.149238e-01 0.146 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 7.149238e-01 0.146 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 7.149238e-01 0.146 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 7.149238e-01 0.146 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.149238e-01 0.146 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 7.149741e-01 0.146 0 0
Metalloprotease DUBs R-HSA-5689901 7.149741e-01 0.146 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 7.149741e-01 0.146 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 7.149741e-01 0.146 0 0
Estrogen-dependent gene expression R-HSA-9018519 7.155965e-01 0.145 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.188791e-01 0.143 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 7.228442e-01 0.141 0 0
Synthesis of PA R-HSA-1483166 7.228442e-01 0.141 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 7.259487e-01 0.139 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 7.259487e-01 0.139 0 0
Packaging Of Telomere Ends R-HSA-171306 7.259487e-01 0.139 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 7.259487e-01 0.139 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.259487e-01 0.139 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 7.259487e-01 0.139 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 7.259487e-01 0.139 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 7.259487e-01 0.139 0 0
Insulin processing R-HSA-264876 7.259487e-01 0.139 0 0
Maturation of hRSV A proteins R-HSA-9828806 7.259487e-01 0.139 0 0
DNA Repair R-HSA-73894 7.261331e-01 0.139 0 0
Chromatin organization R-HSA-4839726 7.268262e-01 0.139 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 7.305781e-01 0.136 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 7.305781e-01 0.136 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 7.305781e-01 0.136 0 0
HCMV Infection R-HSA-9609646 7.307435e-01 0.136 0 0
Peptide chain elongation R-HSA-156902 7.321378e-01 0.135 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.365013e-01 0.133 0 0
HIV elongation arrest and recovery R-HSA-167287 7.365013e-01 0.133 0 0
Pausing and recovery of HIV elongation R-HSA-167290 7.365013e-01 0.133 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.365013e-01 0.133 0 0
Insulin receptor recycling R-HSA-77387 7.365013e-01 0.133 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 7.365013e-01 0.133 0 0
Formation of the Early Elongation Complex R-HSA-113418 7.365013e-01 0.133 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 7.365013e-01 0.133 0 0
Inflammasomes R-HSA-622312 7.365013e-01 0.133 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 7.381280e-01 0.132 0 0
Peroxisomal protein import R-HSA-9033241 7.381280e-01 0.132 0 0
ER-Phagosome pathway R-HSA-1236974 7.384170e-01 0.132 0 0
GABA receptor activation R-HSA-977443 7.454967e-01 0.128 0 0
DNA methylation R-HSA-5334118 7.466482e-01 0.127 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.466482e-01 0.127 0 0
DARPP-32 events R-HSA-180024 7.466482e-01 0.127 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 7.466482e-01 0.127 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 7.466482e-01 0.127 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.490794e-01 0.125 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.490794e-01 0.125 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 7.506249e-01 0.125 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 7.506249e-01 0.125 0 0
HIV Infection R-HSA-162906 7.514856e-01 0.124 0 0
Aquaporin-mediated transport R-HSA-445717 7.526869e-01 0.123 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 7.526869e-01 0.123 0 0
Nucleotide salvage R-HSA-8956321 7.526869e-01 0.123 0 0
Collagen degradation R-HSA-1442490 7.526869e-01 0.123 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.564049e-01 0.121 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 7.564049e-01 0.121 0 0
Neurotransmitter clearance R-HSA-112311 7.564049e-01 0.121 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 7.564049e-01 0.121 0 0
Activation of BH3-only proteins R-HSA-114452 7.564049e-01 0.121 0 0
Metabolism of RNA R-HSA-8953854 7.594401e-01 0.120 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 7.597015e-01 0.119 0 0
Mitochondrial protein import R-HSA-1268020 7.597015e-01 0.119 0 0
Heme signaling R-HSA-9707616 7.597015e-01 0.119 0 0
Signaling by PDGF R-HSA-186797 7.597015e-01 0.119 0 0
Eukaryotic Translation Elongation R-HSA-156842 7.623720e-01 0.118 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 7.623720e-01 0.118 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 7.623720e-01 0.118 0 0
Leishmania parasite growth and survival R-HSA-9664433 7.627728e-01 0.118 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 7.627728e-01 0.118 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 7.646145e-01 0.117 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.657865e-01 0.116 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 7.665432e-01 0.115 0 0
FCGR activation R-HSA-2029481 7.680753e-01 0.115 0 0
Assembly of the pre-replicative complex R-HSA-68867 7.680753e-01 0.115 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 7.745485e-01 0.111 0 0
G0 and Early G1 R-HSA-1538133 7.748073e-01 0.111 0 0
DNA strand elongation R-HSA-69190 7.748073e-01 0.111 0 0
Inwardly rectifying K+ channels R-HSA-1296065 7.748073e-01 0.111 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 7.748073e-01 0.111 0 0
Signaling by WNT in cancer R-HSA-4791275 7.748073e-01 0.111 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 7.748073e-01 0.111 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 7.791471e-01 0.108 0 0
Cellular response to hypoxia R-HSA-1234174 7.797198e-01 0.108 0 0
G alpha (q) signalling events R-HSA-416476 7.816183e-01 0.107 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 7.834813e-01 0.106 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.834813e-01 0.106 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 7.834813e-01 0.106 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 7.834813e-01 0.106 0 0
G-protein beta:gamma signalling R-HSA-397795 7.834813e-01 0.106 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 7.834813e-01 0.106 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 7.834813e-01 0.106 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 7.834813e-01 0.106 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 7.841497e-01 0.106 0 0
Formation of a pool of free 40S subunits R-HSA-72689 7.845180e-01 0.105 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 7.845180e-01 0.105 0 0
Eukaryotic Translation Termination R-HSA-72764 7.845180e-01 0.105 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 7.860606e-01 0.105 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 7.897804e-01 0.102 0 0
Resolution of D-Loop Structures R-HSA-5693537 7.918216e-01 0.101 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 7.918216e-01 0.101 0 0
Heme degradation R-HSA-189483 7.918216e-01 0.101 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 7.918216e-01 0.101 0 0
Miscellaneous transport and binding events R-HSA-5223345 7.918216e-01 0.101 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 7.922404e-01 0.101 0 0
Nicotinate metabolism R-HSA-196807 7.922404e-01 0.101 0 0
Telomere Maintenance R-HSA-157579 7.949358e-01 0.100 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 7.953112e-01 0.099 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 7.982621e-01 0.098 0 0
Protein localization R-HSA-9609507 7.993990e-01 0.097 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 7.998411e-01 0.097 0 0
Dual Incision in GG-NER R-HSA-5696400 7.998411e-01 0.097 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 7.998411e-01 0.097 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 7.998411e-01 0.097 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 7.998411e-01 0.097 0 0
Hyaluronan metabolism R-HSA-2142845 7.998411e-01 0.097 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 7.998411e-01 0.097 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 7.998411e-01 0.097 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 7.998411e-01 0.097 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 8.068058e-01 0.093 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.075522e-01 0.093 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 8.075522e-01 0.093 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 8.075522e-01 0.093 0 0
Hedgehog 'off' state R-HSA-5610787 8.097720e-01 0.092 0 0
ABC-family proteins mediated transport R-HSA-382556 8.097720e-01 0.092 0 0
Selenocysteine synthesis R-HSA-2408557 8.145120e-01 0.089 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.149667e-01 0.089 0 0
HSF1 activation R-HSA-3371511 8.149667e-01 0.089 0 0
Triglyceride catabolism R-HSA-163560 8.149667e-01 0.089 0 0
G1/S-Specific Transcription R-HSA-69205 8.149667e-01 0.089 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.149667e-01 0.089 0 0
HCMV Late Events R-HSA-9610379 8.151101e-01 0.089 0 0
Cellular response to starvation R-HSA-9711097 8.188803e-01 0.087 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 8.205169e-01 0.086 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 8.208283e-01 0.086 0 0
Degradation of AXIN R-HSA-4641257 8.220959e-01 0.085 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 8.220959e-01 0.085 0 0
Degradation of DVL R-HSA-4641258 8.220959e-01 0.085 0 0
Cleavage of the damaged purine R-HSA-110331 8.220959e-01 0.085 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 8.220959e-01 0.085 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 8.220959e-01 0.085 0 0
Viral mRNA Translation R-HSA-192823 8.236922e-01 0.084 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 8.289509e-01 0.081 0 0
Depurination R-HSA-73927 8.289509e-01 0.081 0 0
MET promotes cell motility R-HSA-8875878 8.289509e-01 0.081 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 8.289509e-01 0.081 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 8.289509e-01 0.081 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 8.289509e-01 0.081 0 0
ROS and RNS production in phagocytes R-HSA-1222556 8.312409e-01 0.080 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.324818e-01 0.080 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.324818e-01 0.080 0 0
Neddylation R-HSA-8951664 8.327209e-01 0.080 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 8.355421e-01 0.078 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 8.355421e-01 0.078 0 0
Plasma lipoprotein clearance R-HSA-8964043 8.355421e-01 0.078 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 8.355421e-01 0.078 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 8.362400e-01 0.078 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 8.362400e-01 0.078 0 0
Protein ubiquitination R-HSA-8852135 8.362400e-01 0.078 0 0
Nucleotide Excision Repair R-HSA-5696398 8.367338e-01 0.077 0 0
Selenoamino acid metabolism R-HSA-2408522 8.402194e-01 0.076 0 0
Platelet homeostasis R-HSA-418346 8.408925e-01 0.075 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 8.418798e-01 0.075 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 8.418798e-01 0.075 0 0
HIV Transcription Elongation R-HSA-167169 8.418798e-01 0.075 0 0
Aggrephagy R-HSA-9646399 8.418798e-01 0.075 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.418798e-01 0.075 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 8.449593e-01 0.073 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 8.479735e-01 0.072 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 8.479735e-01 0.072 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 8.479735e-01 0.072 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 8.479735e-01 0.072 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 8.479735e-01 0.072 0 0
Nuclear Receptor transcription pathway R-HSA-383280 8.504438e-01 0.070 0 0
ABC transporter disorders R-HSA-5619084 8.504438e-01 0.070 0 0
Integrin cell surface interactions R-HSA-216083 8.504438e-01 0.070 0 0
Interleukin-10 signaling R-HSA-6783783 8.504438e-01 0.070 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.538328e-01 0.069 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 8.538328e-01 0.069 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 8.538328e-01 0.069 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 8.538328e-01 0.069 0 0
Translation of Structural Proteins R-HSA-9683701 8.538328e-01 0.069 0 0
Ribosome-associated quality control R-HSA-9948299 8.565293e-01 0.067 0 0
Signaling by Hedgehog R-HSA-5358351 8.565293e-01 0.067 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 8.594666e-01 0.066 0 0
Depyrimidination R-HSA-73928 8.594666e-01 0.066 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 8.624606e-01 0.064 0 0
Amyloid fiber formation R-HSA-977225 8.635173e-01 0.064 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 8.638193e-01 0.064 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.639664e-01 0.064 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 8.648836e-01 0.063 0 0
TBC/RABGAPs R-HSA-8854214 8.648836e-01 0.063 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 8.648836e-01 0.063 0 0
G alpha (s) signalling events R-HSA-418555 8.654161e-01 0.063 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 8.665516e-01 0.062 0 0
Phospholipid metabolism R-HSA-1483257 8.686977e-01 0.061 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 8.700921e-01 0.060 0 0
Gap junction trafficking R-HSA-190828 8.700921e-01 0.060 0 0
Surfactant metabolism R-HSA-5683826 8.700921e-01 0.060 0 0
Nucleosome assembly R-HSA-774815 8.751002e-01 0.058 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 8.751002e-01 0.058 0 0
Keratinization R-HSA-6805567 8.770295e-01 0.057 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 8.799154e-01 0.056 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 8.799154e-01 0.056 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 8.799154e-01 0.056 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.799154e-01 0.056 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.799154e-01 0.056 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 8.808949e-01 0.055 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 8.845453e-01 0.053 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 8.845453e-01 0.053 0 0
Synthesis of PC R-HSA-1483191 8.845453e-01 0.053 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 8.845453e-01 0.053 0 0
Rab regulation of trafficking R-HSA-9007101 8.871247e-01 0.052 0 0
Metal ion SLC transporters R-HSA-425410 8.889970e-01 0.051 0 0
Gap junction trafficking and regulation R-HSA-157858 8.932773e-01 0.049 0 0
Infectious disease R-HSA-5663205 8.940039e-01 0.049 0 0
Potential therapeutics for SARS R-HSA-9679191 8.949758e-01 0.048 0 0
MITF-M-dependent gene expression R-HSA-9856651 8.949758e-01 0.048 0 0
TCF dependent signaling in response to WNT R-HSA-201681 8.968918e-01 0.047 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.973928e-01 0.047 0 0
Chromosome Maintenance R-HSA-73886 8.987176e-01 0.046 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.013498e-01 0.045 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.013498e-01 0.045 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.013498e-01 0.045 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.041027e-01 0.044 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 9.051545e-01 0.043 0 0
Orc1 removal from chromatin R-HSA-68949 9.051545e-01 0.043 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 9.051545e-01 0.043 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.051545e-01 0.043 0 0
Viral Infection Pathways R-HSA-9824446 9.084281e-01 0.042 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 9.088126e-01 0.042 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.088126e-01 0.042 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.123299e-01 0.040 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.123299e-01 0.040 0 0
Paracetamol ADME R-HSA-9753281 9.157117e-01 0.038 0 0
Interferon gamma signaling R-HSA-877300 9.159964e-01 0.038 0 0
Organelle biogenesis and maintenance R-HSA-1852241 9.163925e-01 0.038 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 9.189633e-01 0.037 0 0
Dectin-2 family R-HSA-5621480 9.220896e-01 0.035 0 0
Dual incision in TC-NER R-HSA-6782135 9.250955e-01 0.034 0 0
Reproduction R-HSA-1474165 9.252680e-01 0.034 0 0
Sensory perception of taste R-HSA-9717189 9.273350e-01 0.033 0 0
Extension of Telomeres R-HSA-180786 9.279855e-01 0.032 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.279855e-01 0.032 0 0
Regulation of beta-cell development R-HSA-186712 9.279855e-01 0.032 0 0
HATs acetylate histones R-HSA-3214847 9.293443e-01 0.032 0 0
Circadian clock R-HSA-9909396 9.293494e-01 0.032 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.293494e-01 0.032 0 0
rRNA processing R-HSA-72312 9.295597e-01 0.032 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 9.307643e-01 0.031 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 9.307643e-01 0.031 0 0
Signaling by Nuclear Receptors R-HSA-9006931 9.327169e-01 0.030 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.334360e-01 0.030 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.352863e-01 0.029 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.360047e-01 0.029 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 9.360047e-01 0.029 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 9.360047e-01 0.029 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.384745e-01 0.028 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.408491e-01 0.026 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.474378e-01 0.023 0 0
Post-translational protein modification R-HSA-597592 9.491057e-01 0.023 0 0
Transcription of the HIV genome R-HSA-167172 9.494670e-01 0.023 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.532937e-01 0.021 0 0
COPII-mediated vesicle transport R-HSA-204005 9.532937e-01 0.021 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 9.532937e-01 0.021 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.550971e-01 0.020 0 0
Hedgehog 'on' state R-HSA-5632684 9.550971e-01 0.020 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 9.550971e-01 0.020 0 0
Metabolism of porphyrins R-HSA-189445 9.550971e-01 0.020 0 0
Purine catabolism R-HSA-74259 9.568310e-01 0.019 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 9.601008e-01 0.018 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.616418e-01 0.017 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.616418e-01 0.017 0 0
Gene expression (Transcription) R-HSA-74160 9.629743e-01 0.016 0 0
UCH proteinases R-HSA-5689603 9.631233e-01 0.016 0 0
Peptide hormone metabolism R-HSA-2980736 9.643388e-01 0.016 0 0
Generic Transcription Pathway R-HSA-212436 9.644204e-01 0.016 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 9.655145e-01 0.015 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.672338e-01 0.014 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.672338e-01 0.014 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.697167e-01 0.013 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.720118e-01 0.012 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.729301e-01 0.012 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.730933e-01 0.012 0 0
Pyruvate metabolism R-HSA-70268 9.770179e-01 0.010 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.779063e-01 0.010 0 0
Downstream TCR signaling R-HSA-202424 9.795815e-01 0.009 0 0
Neurotransmitter release cycle R-HSA-112310 9.795815e-01 0.009 0 0
RNA Polymerase II Transcription R-HSA-73857 9.815184e-01 0.008 0 0
Collagen formation R-HSA-1474290 9.832353e-01 0.007 0 0
Mitochondrial translation elongation R-HSA-5389840 9.851062e-01 0.007 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 9.856823e-01 0.006 0 0
Mitochondrial translation initiation R-HSA-5368286 9.862362e-01 0.006 0 0
Developmental Cell Lineages R-HSA-9734767 9.863758e-01 0.006 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.867687e-01 0.006 0 0
Regulation of endogenous retroelements R-HSA-9842860 9.882458e-01 0.005 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.887006e-01 0.005 0 0
Metabolism of nucleotides R-HSA-15869 9.903092e-01 0.004 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.904944e-01 0.004 0 0
Mitochondrial translation termination R-HSA-5419276 9.914285e-01 0.004 0 0
TCR signaling R-HSA-202403 9.917604e-01 0.004 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.917604e-01 0.004 0 0
Translation R-HSA-72766 9.919260e-01 0.004 0 0
GPCR downstream signalling R-HSA-388396 9.933804e-01 0.003 0 0
Extracellular matrix organization R-HSA-1474244 9.938848e-01 0.003 0 0
Mitochondrial biogenesis R-HSA-1592230 9.942253e-01 0.003 0 0
G alpha (i) signalling events R-HSA-418594 9.942326e-01 0.003 0 0
Drug ADME R-HSA-9748784 9.954141e-01 0.002 0 0
Nucleotide catabolism R-HSA-8956319 9.965454e-01 0.002 0 0
Transport of small molecules R-HSA-382551 9.971946e-01 0.001 0 0
Signaling by GPCR R-HSA-372790 9.974903e-01 0.001 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.976794e-01 0.001 0 0
Mitochondrial translation R-HSA-5368287 9.977641e-01 0.001 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.983051e-01 0.001 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.983061e-01 0.001 0 0
Metabolism of proteins R-HSA-392499 9.984993e-01 0.001 0 0
Gastrulation R-HSA-9758941 9.986095e-01 0.001 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.994356e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.995766e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.996663e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.996917e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.997665e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.998676e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999258e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999412e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999464e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999890e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999905e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999924e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999960e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999966e-01 0.000 0 0
Biological oxidations R-HSA-211859 9.999992e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999998e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999999e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.110223e-16 15.955 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.110223e-16 15.955 0 0
Eukaryotic Translation Elongation R-HSA-156842 1.110223e-16 15.955 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.110223e-16 15.955 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.110223e-16 15.955 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.110223e-16 15.955 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Peptide chain elongation R-HSA-156902 2.220446e-16 15.654 0 0
Aggrephagy R-HSA-9646399 5.551115e-16 15.256 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 5.551115e-16 15.256 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 9.992007e-16 15.000 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.110223e-15 14.955 0 0
M Phase R-HSA-68886 1.443290e-15 14.841 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.665335e-15 14.778 0 0
Formation of a pool of free 40S subunits R-HSA-72689 2.109424e-15 14.676 0 0
Cell-Cell communication R-HSA-1500931 2.331468e-15 14.632 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 2.442491e-15 14.612 0 0
Cell Cycle R-HSA-1640170 8.659740e-15 14.062 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 1.865175e-14 13.729 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 1.865175e-14 13.729 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 2.331468e-14 13.632 0 0
Signaling by ROBO receptors R-HSA-376176 2.609024e-14 13.584 0 0
Cellular response to heat stress R-HSA-3371556 2.919887e-14 13.535 0 0
Ribosome-associated quality control R-HSA-9948299 3.996803e-14 13.398 0 0
Eukaryotic Translation Termination R-HSA-72764 9.348078e-14 13.029 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.014744e-13 12.994 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.052491e-13 12.978 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.362244e-13 12.866 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 2.414735e-13 12.617 0 0
Developmental Biology R-HSA-1266738 2.730038e-13 12.564 0 0
Selenocysteine synthesis R-HSA-2408557 3.430589e-13 12.465 0 0
Cell junction organization R-HSA-446728 3.596012e-13 12.444 0 0
Viral mRNA Translation R-HSA-192823 5.196954e-13 12.284 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 8.116841e-13 12.091 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.162181e-12 11.935 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 1.546319e-12 11.811 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.485478e-12 11.828 0 0
Influenza Infection R-HSA-168255 1.556755e-12 11.808 0 0
Metabolism of RNA R-HSA-8953854 2.051581e-12 11.688 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.165379e-12 11.664 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 3.952838e-12 11.403 0 0
Transport of connexons to the plasma membrane R-HSA-190872 3.878342e-12 11.411 0 0
Cell Cycle, Mitotic R-HSA-69278 4.484857e-12 11.348 0 0
Interferon Signaling R-HSA-913531 8.583023e-12 11.066 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 8.634427e-12 11.064 0 0
Translation initiation complex formation R-HSA-72649 1.006795e-11 10.997 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.440348e-11 10.842 0 0
Viral Infection Pathways R-HSA-9824446 1.537825e-11 10.813 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.661804e-11 10.779 0 0
PKR-mediated signaling R-HSA-9833482 1.850187e-11 10.733 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.259504e-11 10.646 0 0
Cellular Senescence R-HSA-2559583 3.333844e-11 10.477 0 0
HSF1-dependent transactivation R-HSA-3371571 3.395029e-11 10.469 0 0
Gap junction trafficking R-HSA-190828 3.537892e-11 10.451 0 0
Apoptosis R-HSA-109581 4.759237e-11 10.322 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.589118e-11 10.253 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.589118e-11 10.253 0 0
Protein folding R-HSA-391251 5.596767e-11 10.252 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 6.176282e-11 10.209 0 0
Gap junction assembly R-HSA-190861 7.787393e-11 10.109 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.024860e-10 9.989 0 0
Post NMDA receptor activation events R-HSA-438064 9.932732e-11 10.003 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.154896e-10 9.937 0 0
Selective autophagy R-HSA-9663891 1.211079e-10 9.917 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.304304e-10 9.885 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.406714e-10 9.852 0 0
Gap junction trafficking and regulation R-HSA-157858 1.513105e-10 9.820 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.521953e-10 9.818 0 0
Mitotic Anaphase R-HSA-68882 1.878340e-10 9.726 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.100984e-10 9.678 0 0
Selenoamino acid metabolism R-HSA-2408522 2.650110e-10 9.577 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 3.679772e-10 9.434 0 0
Cellular response to starvation R-HSA-9711097 5.060266e-10 9.296 0 0
Cell-cell junction organization R-HSA-421270 5.953317e-10 9.225 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 5.976848e-10 9.224 0 0
Recycling pathway of L1 R-HSA-437239 6.696624e-10 9.174 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.861022e-10 9.164 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 7.198246e-10 9.143 0 0
Programmed Cell Death R-HSA-5357801 7.623704e-10 9.118 0 0
Adherens junctions interactions R-HSA-418990 8.589697e-10 9.066 0 0
HCMV Early Events R-HSA-9609690 9.274217e-10 9.033 0 0
Translation R-HSA-72766 1.047173e-09 8.980 0 0
G2/M Transition R-HSA-69275 1.118021e-09 8.952 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.407535e-09 8.852 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 2.136957e-09 8.670 0 0
SARS-CoV-2-host interactions R-HSA-9705683 2.426450e-09 8.615 0 0
Mitotic Prometaphase R-HSA-68877 2.470936e-09 8.607 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.804590e-09 8.552 0 0
Signal Transduction R-HSA-162582 2.921165e-09 8.534 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 3.370490e-09 8.472 0 0
rRNA processing R-HSA-72312 3.616856e-09 8.442 0 0
Apoptotic execution phase R-HSA-75153 3.811692e-09 8.419 0 0
Separation of Sister Chromatids R-HSA-2467813 4.311236e-09 8.365 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.557095e-09 8.341 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 6.873423e-09 8.163 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 7.480149e-09 8.126 0 0
Regulation of CDH1 Function R-HSA-9764561 7.702039e-09 8.113 0 0
Interleukin-12 signaling R-HSA-9020591 1.029907e-08 7.987 0 0
HCMV Infection R-HSA-9609646 1.962065e-08 7.707 0 0
Cilium Assembly R-HSA-5617833 2.329591e-08 7.633 0 0
Signaling by RAS mutants R-HSA-6802949 2.679841e-08 7.572 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.679841e-08 7.572 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.679841e-08 7.572 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.679841e-08 7.572 0 0
Autophagy R-HSA-9612973 2.501721e-08 7.602 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 2.679841e-08 7.572 0 0
L1CAM interactions R-HSA-373760 2.716864e-08 7.566 0 0
Attenuation phase R-HSA-3371568 3.330817e-08 7.477 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 4.032802e-08 7.394 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 4.839993e-08 7.315 0 0
Signaling by RAF1 mutants R-HSA-9656223 5.517253e-08 7.258 0 0
Macroautophagy R-HSA-1632852 5.694878e-08 7.245 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 6.583378e-08 7.182 0 0
Interleukin-12 family signaling R-HSA-447115 8.072862e-08 7.093 0 0
HSF1 activation R-HSA-3371511 8.653614e-08 7.063 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 8.726767e-08 7.059 0 0
Diseases of programmed cell death R-HSA-9645723 9.445942e-08 7.025 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.028389e-07 6.988 0 0
Infectious disease R-HSA-5663205 1.124654e-07 6.949 0 0
Cell Cycle Checkpoints R-HSA-69620 1.202380e-07 6.920 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.478080e-07 6.830 0 0
Signaling by PTK6 R-HSA-8848021 1.550616e-07 6.809 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.550616e-07 6.809 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.896623e-07 6.722 0 0
Mitotic Prophase R-HSA-68875 1.909997e-07 6.719 0 0
Muscle contraction R-HSA-397014 2.119894e-07 6.674 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 2.195409e-07 6.658 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.199687e-07 6.658 0 0
Signaling by ERBB2 R-HSA-1227986 4.896179e-07 6.310 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 4.896179e-07 6.310 0 0
Kinesins R-HSA-983189 4.896179e-07 6.310 0 0
G2/M Checkpoints R-HSA-69481 4.969328e-07 6.304 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 7.145414e-07 6.146 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 7.332392e-07 6.135 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 7.609671e-07 6.119 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 8.921262e-07 6.050 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 9.690694e-07 6.014 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.005786e-06 5.997 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.119371e-06 5.951 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.436989e-06 5.843 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.465829e-06 5.834 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.585514e-06 5.587 0 0
Glycolysis R-HSA-70171 2.867926e-06 5.542 0 0
MAPK family signaling cascades R-HSA-5683057 3.176508e-06 5.498 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.252188e-06 5.488 0 0
Oncogene Induced Senescence R-HSA-2559585 3.287447e-06 5.483 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.456221e-06 5.461 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.493752e-06 5.457 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.030838e-06 5.395 0 0
Disease R-HSA-1643685 4.258097e-06 5.371 0 0
RMTs methylate histone arginines R-HSA-3214858 4.268997e-06 5.370 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 4.313946e-06 5.365 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 5.075678e-06 5.295 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 5.291653e-06 5.276 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 5.502142e-06 5.259 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 5.960984e-06 5.225 0 0
ISG15 antiviral mechanism R-HSA-1169408 5.393332e-06 5.268 0 0
Gene Silencing by RNA R-HSA-211000 7.310169e-06 5.136 0 0
Platelet activation, signaling and aggregation R-HSA-76002 8.431220e-06 5.074 0 0
RAF/MAP kinase cascade R-HSA-5673001 8.635426e-06 5.064 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 8.749538e-06 5.058 0 0
Intraflagellar transport R-HSA-5620924 8.892299e-06 5.051 0 0
Immune System R-HSA-168256 9.874078e-06 5.006 0 0
Hemostasis R-HSA-109582 1.244255e-05 4.905 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.274147e-05 4.895 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.295360e-05 4.888 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.353146e-05 4.869 0 0
Striated Muscle Contraction R-HSA-390522 1.353365e-05 4.869 0 0
MAP2K and MAPK activation R-HSA-5674135 1.366953e-05 4.864 0 0
Metalloprotease DUBs R-HSA-5689901 1.460628e-05 4.835 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 1.645011e-05 4.784 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.667229e-05 4.778 0 0
Signaling by VEGF R-HSA-194138 1.824169e-05 4.739 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.854788e-05 4.732 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.854788e-05 4.732 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.697564e-05 4.770 0 0
SARS-CoV Infections R-HSA-9679506 1.842702e-05 4.735 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.101131e-05 4.678 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.316305e-05 4.635 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.316305e-05 4.635 0 0
Metabolism of proteins R-HSA-392499 2.365163e-05 4.626 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 2.433445e-05 4.614 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 2.433445e-05 4.614 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.433445e-05 4.614 0 0
PRC2 methylates histones and DNA R-HSA-212300 2.486237e-05 4.604 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.486237e-05 4.604 0 0
Glucose metabolism R-HSA-70326 2.562810e-05 4.591 0 0
COPI-mediated anterograde transport R-HSA-6807878 2.651338e-05 4.577 0 0
Transmission across Chemical Synapses R-HSA-112315 2.678361e-05 4.572 0 0
DNA methylation R-HSA-5334118 2.919176e-05 4.535 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 2.991321e-05 4.524 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.017035e-05 4.520 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 3.281998e-05 4.484 0 0
Nuclear Envelope Breakdown R-HSA-2980766 3.750070e-05 4.426 0 0
Hedgehog 'off' state R-HSA-5610787 4.075168e-05 4.390 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 4.332873e-05 4.363 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 4.792050e-05 4.319 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 4.350446e-05 4.361 0 0
Gluconeogenesis R-HSA-70263 4.533107e-05 4.344 0 0
Amyloid fiber formation R-HSA-977225 4.886307e-05 4.311 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 5.760606e-05 4.240 0 0
Estrogen-dependent gene expression R-HSA-9018519 5.890583e-05 4.230 0 0
Assembly of the pre-replicative complex R-HSA-68867 6.269559e-05 4.203 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 6.525163e-05 4.185 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 6.641606e-05 4.178 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 6.912917e-05 4.160 0 0
Signaling by Hedgehog R-HSA-5358351 6.965531e-05 4.157 0 0
Platelet degranulation R-HSA-114608 7.083598e-05 4.150 0 0
Meiotic recombination R-HSA-912446 7.170034e-05 4.144 0 0
Negative regulation of MAPK pathway R-HSA-5675221 7.295738e-05 4.137 0 0
Meiosis R-HSA-1500620 7.734595e-05 4.112 0 0
Long-term potentiation R-HSA-9620244 7.839612e-05 4.106 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 7.991280e-05 4.097 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 8.030834e-05 4.095 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.300371e-05 4.081 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 8.575669e-05 4.067 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 8.575669e-05 4.067 0 0
Regulation of PTEN localization R-HSA-8948747 8.797365e-05 4.056 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.370845e-05 4.028 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 9.492692e-05 4.023 0 0
RAF activation R-HSA-5673000 9.656325e-05 4.015 0 0
Signaling by EGFR in Cancer R-HSA-1643713 9.734307e-05 4.012 0 0
Defective pyroptosis R-HSA-9710421 1.008348e-04 3.996 0 0
UCH proteinases R-HSA-5689603 1.053214e-04 3.977 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.254752e-04 3.901 0 0
Co-inhibition by PD-1 R-HSA-389948 1.261617e-04 3.899 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.093666e-04 3.961 0 0
Nephrin family interactions R-HSA-373753 1.330306e-04 3.876 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 1.367435e-04 3.864 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.427791e-04 3.845 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.599451e-04 3.796 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.627366e-04 3.789 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.651914e-04 3.782 0 0
Late endosomal microautophagy R-HSA-9615710 1.781619e-04 3.749 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.839224e-04 3.735 0 0
Signaling by WNT R-HSA-195721 1.971313e-04 3.705 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 2.039184e-04 3.691 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 2.043627e-04 3.690 0 0
Spry regulation of FGF signaling R-HSA-1295596 2.117110e-04 3.674 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 2.117435e-04 3.674 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.135038e-04 3.671 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.149959e-04 3.668 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 2.630352e-04 3.580 0 0
Degradation of CDH1 R-HSA-9766229 2.439000e-04 3.613 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.418302e-04 3.616 0 0
Trafficking of AMPA receptors R-HSA-399719 2.578532e-04 3.589 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.578532e-04 3.589 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 2.266819e-04 3.645 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 2.630352e-04 3.580 0 0
Adaptive Immune System R-HSA-1280218 2.671912e-04 3.573 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.832652e-04 3.548 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 2.936909e-04 3.532 0 0
Josephin domain DUBs R-HSA-5689877 2.936909e-04 3.532 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 2.936909e-04 3.532 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 3.061214e-04 3.514 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 3.061214e-04 3.514 0 0
Semaphorin interactions R-HSA-373755 3.465601e-04 3.460 0 0
Centrosome maturation R-HSA-380287 3.514084e-04 3.454 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 3.589521e-04 3.445 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 3.589521e-04 3.445 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 3.645860e-04 3.438 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 3.747969e-04 3.426 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.963072e-04 3.402 0 0
Neurodegenerative Diseases R-HSA-8863678 3.963072e-04 3.402 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 3.963072e-04 3.402 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 4.098781e-04 3.387 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 4.106334e-04 3.387 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.106334e-04 3.387 0 0
Meiotic synapsis R-HSA-1221632 4.126644e-04 3.384 0 0
Smooth Muscle Contraction R-HSA-445355 4.126644e-04 3.384 0 0
ER to Golgi Anterograde Transport R-HSA-199977 4.266515e-04 3.370 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.540383e-04 3.343 0 0
Maturation of protein E R-HSA-9683683 4.540383e-04 3.343 0 0
Maturation of protein E R-HSA-9694493 4.540383e-04 3.343 0 0
Signaling by Hippo R-HSA-2028269 4.576424e-04 3.339 0 0
Host Interactions of HIV factors R-HSA-162909 4.602484e-04 3.337 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 4.717036e-04 3.326 0 0
ESR-mediated signaling R-HSA-8939211 4.898903e-04 3.310 0 0
Signaling by Interleukins R-HSA-449147 4.903333e-04 3.310 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.983312e-04 3.302 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 5.047951e-04 3.297 0 0
HDACs deacetylate histones R-HSA-3214815 5.280350e-04 3.277 0 0
Regulation of endogenous retroelements R-HSA-9842860 5.426193e-04 3.266 0 0
DNA Double Strand Break Response R-HSA-5693606 5.433246e-04 3.265 0 0
Membrane Trafficking R-HSA-199991 5.761312e-04 3.239 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 5.820098e-04 3.235 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.848092e-04 3.233 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 5.950406e-04 3.225 0 0
EPH-Ephrin signaling R-HSA-2682334 6.541288e-04 3.184 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 6.857887e-04 3.164 0 0
Packaging Of Telomere Ends R-HSA-171306 6.915111e-04 3.160 0 0
Regulation of signaling by CBL R-HSA-912631 7.175251e-04 3.144 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 7.457210e-04 3.127 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 7.460113e-04 3.127 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 7.460113e-04 3.127 0 0
Ovarian tumor domain proteases R-HSA-5689896 7.941041e-04 3.100 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 9.065973e-04 3.043 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 9.699430e-04 3.013 0 0
Ub-specific processing proteases R-HSA-5689880 9.447180e-04 3.025 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 9.751725e-04 3.011 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.049010e-03 2.979 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 9.535590e-04 3.021 0 0
Activation of BH3-only proteins R-HSA-114452 1.138777e-03 2.944 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.160949e-03 2.935 0 0
MHC class II antigen presentation R-HSA-2132295 1.199370e-03 2.921 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.252876e-03 2.902 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 1.252876e-03 2.902 0 0
Gene expression (Transcription) R-HSA-74160 1.256403e-03 2.901 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.305342e-03 2.884 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.307696e-03 2.883 0 0
EGFR downregulation R-HSA-182971 1.329829e-03 2.876 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 1.334988e-03 2.875 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.339914e-03 2.873 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.372572e-03 2.862 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.416349e-03 2.849 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 1.465535e-03 2.834 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 1.465535e-03 2.834 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.465535e-03 2.834 0 0
Modulation by Mtb of host immune system R-HSA-9637628 1.465535e-03 2.834 0 0
Generic Transcription Pathway R-HSA-212436 1.473984e-03 2.832 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.545053e-03 2.811 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.566180e-03 2.805 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 1.566180e-03 2.805 0 0
mTORC1-mediated signalling R-HSA-166208 1.566180e-03 2.805 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 1.566180e-03 2.805 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.585037e-03 2.800 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.585037e-03 2.800 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.585037e-03 2.800 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 1.585037e-03 2.800 0 0
Protein methylation R-HSA-8876725 1.585037e-03 2.800 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.585037e-03 2.800 0 0
Nuclear Receptor transcription pathway R-HSA-383280 1.608281e-03 2.794 0 0
RNA Polymerase I Transcription R-HSA-73864 1.608281e-03 2.794 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.673085e-03 2.776 0 0
Negative regulation of FLT3 R-HSA-9706369 1.977720e-03 2.704 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.056182e-03 2.687 0 0
Deadenylation of mRNA R-HSA-429947 2.204789e-03 2.657 0 0
Signaling by EGFR R-HSA-177929 2.232892e-03 2.651 0 0
Ion homeostasis R-HSA-5578775 2.232892e-03 2.651 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.244595e-03 2.649 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.277057e-03 2.643 0 0
Homology Directed Repair R-HSA-5693538 2.289088e-03 2.640 0 0
mRNA Splicing R-HSA-72172 2.322019e-03 2.634 0 0
Nuclear import of Rev protein R-HSA-180746 2.356341e-03 2.628 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 2.356341e-03 2.628 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 2.518951e-03 2.599 0 0
Nucleosome assembly R-HSA-774815 2.518951e-03 2.599 0 0
DAG and IP3 signaling R-HSA-1489509 2.518951e-03 2.599 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.589430e-03 2.587 0 0
Regulation of CDH11 function R-HSA-9762292 2.671613e-03 2.573 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.671613e-03 2.573 0 0
Pexophagy R-HSA-9664873 2.671613e-03 2.573 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 2.702530e-03 2.568 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.768379e-03 2.558 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 2.792323e-03 2.554 0 0
RNA Polymerase II Transcription R-HSA-73857 3.051568e-03 2.515 0 0
FLT3 signaling in disease R-HSA-9682385 3.056928e-03 2.515 0 0
TCR signaling R-HSA-202403 3.102441e-03 2.508 0 0
Telomere Maintenance R-HSA-157579 3.170252e-03 2.499 0 0
Neuronal System R-HSA-112316 3.190684e-03 2.496 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 3.296299e-03 2.482 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 3.542958e-03 2.451 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 4.277825e-03 2.369 0 0
Signaling by ERBB4 R-HSA-1236394 3.588703e-03 2.445 0 0
Translesion Synthesis by POLH R-HSA-110320 4.277825e-03 2.369 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 3.461945e-03 2.461 0 0
HATs acetylate histones R-HSA-3214847 3.660412e-03 2.436 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.461945e-03 2.461 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 3.996112e-03 2.398 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.426205e-03 2.354 0 0
Stabilization of p53 R-HSA-69541 4.393229e-03 2.357 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.426205e-03 2.354 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 4.047414e-03 2.393 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 3.887943e-03 2.410 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 3.887943e-03 2.410 0 0
RAS processing R-HSA-9648002 4.393229e-03 2.357 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 4.373841e-03 2.359 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.927189e-03 2.406 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.426205e-03 2.354 0 0
NF-kB is activated and signals survival R-HSA-209560 4.426205e-03 2.354 0 0
Cleavage of the damaged purine R-HSA-110331 3.461945e-03 2.461 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 3.516199e-03 2.454 0 0
Depurination R-HSA-73927 3.906580e-03 2.408 0 0
DNA Replication R-HSA-69306 3.927189e-03 2.406 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 4.046994e-03 2.393 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 3.580891e-03 2.446 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.646919e-03 2.333 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 4.646919e-03 2.333 0 0
HCMV Late Events R-HSA-9610379 4.867660e-03 2.313 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 4.924320e-03 2.308 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 4.924320e-03 2.308 0 0
Negative regulation of MET activity R-HSA-6807004 5.066406e-03 2.295 0 0
Glycogen synthesis R-HSA-3322077 5.066406e-03 2.295 0 0
Deubiquitination R-HSA-5688426 5.238691e-03 2.281 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 5.245917e-03 2.280 0 0
Intracellular signaling by second messengers R-HSA-9006925 5.344693e-03 2.272 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 5.353028e-03 2.271 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 5.353028e-03 2.271 0 0
Reproduction R-HSA-1474165 5.470925e-03 2.262 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 5.502304e-03 2.259 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 5.502304e-03 2.259 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 5.502304e-03 2.259 0 0
FLT3 Signaling R-HSA-9607240 5.502304e-03 2.259 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 5.540059e-03 2.256 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 5.540059e-03 2.256 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 5.540059e-03 2.256 0 0
IRAK1 recruits IKK complex R-HSA-937039 5.540059e-03 2.256 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 5.540059e-03 2.256 0 0
VLDLR internalisation and degradation R-HSA-8866427 5.540059e-03 2.256 0 0
p75NTR recruits signalling complexes R-HSA-209543 5.540059e-03 2.256 0 0
Signaling by NOTCH R-HSA-157118 5.665306e-03 2.247 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 5.952757e-03 2.225 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 5.952757e-03 2.225 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 5.952757e-03 2.225 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 6.038335e-03 2.219 0 0
Budding and maturation of HIV virion R-HSA-162588 6.038335e-03 2.219 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 6.038335e-03 2.219 0 0
G-protein mediated events R-HSA-112040 6.170369e-03 2.210 0 0
Regulated Necrosis R-HSA-5218859 6.697471e-03 2.174 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 6.808837e-03 2.167 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 6.808837e-03 2.167 0 0
Depyrimidination R-HSA-73928 6.808837e-03 2.167 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 6.826870e-03 2.166 0 0
Neutrophil degranulation R-HSA-6798695 6.899909e-03 2.161 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 6.942888e-03 2.158 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 6.942888e-03 2.158 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 6.942888e-03 2.158 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 6.942888e-03 2.158 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 6.942888e-03 2.158 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 6.942888e-03 2.158 0 0
Assembly Of The HIV Virion R-HSA-175474 6.942888e-03 2.158 0 0
Chromosome Maintenance R-HSA-73886 7.028975e-03 2.153 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 7.383447e-03 2.132 0 0
Signaling by FGFR4 R-HSA-5654743 7.542350e-03 2.122 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 7.586729e-03 2.120 0 0
Signaling by FGFR1 R-HSA-5654736 7.586729e-03 2.120 0 0
Manipulation of host energy metabolism R-HSA-9636667 7.747233e-03 2.111 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 9.812178e-03 2.008 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 7.710893e-03 2.113 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 8.661736e-03 2.062 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 1.081043e-02 1.966 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.081043e-02 1.966 0 0
Protein ubiquitination R-HSA-8852135 1.141195e-02 1.943 0 0
Regulation of mitotic cell cycle R-HSA-453276 8.487412e-03 2.071 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 8.487412e-03 2.071 0 0
Translesion synthesis by REV1 R-HSA-110312 9.960805e-03 2.002 0 0
Regulation of Apoptosis R-HSA-169911 1.081043e-02 1.966 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 8.549925e-03 2.068 0 0
Ca2+ pathway R-HSA-4086398 9.868245e-03 2.006 0 0
Breakdown of the nuclear lamina R-HSA-352238 7.747233e-03 2.111 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 1.059375e-02 1.975 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 8.297192e-03 2.081 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 9.802357e-03 2.009 0 0
HIV Life Cycle R-HSA-162587 1.084220e-02 1.965 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 7.854629e-03 2.105 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.710893e-03 2.113 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 7.710893e-03 2.113 0 0
NOD1/2 Signaling Pathway R-HSA-168638 9.693742e-03 2.014 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 9.693742e-03 2.014 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 7.710893e-03 2.113 0 0
Regulation of pyruvate metabolism R-HSA-9861718 1.009361e-02 1.996 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.151690e-02 1.939 0 0
NRIF signals cell death from the nucleus R-HSA-205043 8.297192e-03 2.081 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 9.812178e-03 2.008 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 8.042666e-03 2.095 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 7.710893e-03 2.113 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.067070e-02 1.972 0 0
PLC beta mediated events R-HSA-112043 1.152547e-02 1.938 0 0
MAP kinase activation R-HSA-450294 1.152547e-02 1.938 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 9.960805e-03 2.002 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 1.106912e-02 1.956 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 7.710893e-03 2.113 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 8.297192e-03 2.081 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 8.332669e-03 2.079 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 8.356178e-03 2.078 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.151690e-02 1.939 0 0
Signaling by FGFR3 R-HSA-5654741 9.182269e-03 2.037 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.176815e-03 2.037 0 0
p75NTR signals via NF-kB R-HSA-193639 9.960805e-03 2.002 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.182668e-02 1.927 0 0
Translesion synthesis by POLI R-HSA-5656121 1.182668e-02 1.927 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 1.182668e-02 1.927 0 0
Regulation of BACH1 activity R-HSA-9708530 1.182668e-02 1.927 0 0
Calmodulin induced events R-HSA-111933 1.201524e-02 1.920 0 0
CaM pathway R-HSA-111997 1.201524e-02 1.920 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.265346e-02 1.898 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.265346e-02 1.898 0 0
HIV Infection R-HSA-162906 1.314640e-02 1.881 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.328626e-02 1.877 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.338651e-02 1.873 0 0
Diseases of Cellular Senescence R-HSA-9630747 1.338651e-02 1.873 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.338651e-02 1.873 0 0
Diseases of cellular response to stress R-HSA-9675132 1.338651e-02 1.873 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.338651e-02 1.873 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.338651e-02 1.873 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.338651e-02 1.873 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.338651e-02 1.873 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.338651e-02 1.873 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.338651e-02 1.873 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.338651e-02 1.873 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.338651e-02 1.873 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.338651e-02 1.873 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.338651e-02 1.873 0 0
Developmental Cell Lineages R-HSA-9734767 1.364447e-02 1.865 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 1.390296e-02 1.857 0 0
Translesion synthesis by POLK R-HSA-5655862 1.390296e-02 1.857 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 1.390296e-02 1.857 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 1.390296e-02 1.857 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.390296e-02 1.857 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.390296e-02 1.857 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.451484e-02 1.838 0 0
Ion transport by P-type ATPases R-HSA-936837 1.451484e-02 1.838 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 1.470256e-02 1.833 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.470256e-02 1.833 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.491472e-02 1.826 0 0
Sensory processing of sound R-HSA-9659379 1.503191e-02 1.823 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 1.537822e-02 1.813 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.537822e-02 1.813 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.537822e-02 1.813 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 1.566058e-02 1.805 0 0
Hedgehog ligand biogenesis R-HSA-5358346 1.566058e-02 1.805 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.591742e-02 1.798 0 0
Signaling by MET R-HSA-6806834 1.605577e-02 1.794 0 0
Signaling by FGFR2 R-HSA-5654738 1.605577e-02 1.794 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 1.619149e-02 1.791 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.619149e-02 1.791 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.619149e-02 1.791 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 1.619691e-02 1.791 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 1.619691e-02 1.791 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.619691e-02 1.791 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 1.619691e-02 1.791 0 0
Glycogen storage diseases R-HSA-3229121 1.619691e-02 1.791 0 0
Cellular response to chemical stress R-HSA-9711123 1.621234e-02 1.790 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.641984e-02 1.785 0 0
Signaling by ALK in cancer R-HSA-9700206 1.641984e-02 1.785 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.692301e-02 1.772 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 1.699235e-02 1.770 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.699235e-02 1.770 0 0
Chromatin modifying enzymes R-HSA-3247509 1.702906e-02 1.769 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 1.724782e-02 1.763 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.778136e-02 1.750 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.778136e-02 1.750 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 1.778136e-02 1.750 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.810136e-02 1.742 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 1.840213e-02 1.735 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.871496e-02 1.728 0 0
Ephrin signaling R-HSA-3928664 1.871496e-02 1.728 0 0
Vesicle-mediated transport R-HSA-5653656 1.909781e-02 1.719 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 1.926205e-02 1.715 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 1.926205e-02 1.715 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.932881e-02 1.714 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 1.947509e-02 1.711 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 1.961052e-02 1.708 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 1.989204e-02 1.701 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.989204e-02 1.701 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 2.066640e-02 1.685 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.128849e-02 1.672 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 2.142482e-02 1.669 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 2.146264e-02 1.668 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.146414e-02 1.668 0 0
G alpha (z) signalling events R-HSA-418597 2.146414e-02 1.668 0 0
Interleukin-17 signaling R-HSA-448424 2.212057e-02 1.655 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.249194e-02 1.648 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.249194e-02 1.648 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.249194e-02 1.648 0 0
Signaling by FGFR R-HSA-190236 2.249194e-02 1.648 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 2.252258e-02 1.647 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 2.312041e-02 1.636 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 2.312041e-02 1.636 0 0
MTOR signalling R-HSA-165159 2.318512e-02 1.635 0 0
Ca-dependent events R-HSA-111996 2.318512e-02 1.635 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.329870e-02 1.633 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.329870e-02 1.633 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 2.360308e-02 1.627 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 2.373971e-02 1.625 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 2.373971e-02 1.625 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 2.373971e-02 1.625 0 0
Formation of definitive endoderm R-HSA-9823730 2.444465e-02 1.612 0 0
Signal transduction by L1 R-HSA-445144 2.444465e-02 1.612 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 2.444465e-02 1.612 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 2.520657e-02 1.598 0 0
Response of Mtb to phagocytosis R-HSA-9637690 2.520657e-02 1.598 0 0
Pyruvate metabolism R-HSA-70268 2.616201e-02 1.582 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 2.621001e-02 1.582 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 2.734217e-02 1.563 0 0
G1 Phase R-HSA-69236 2.734217e-02 1.563 0 0
Cyclin D associated events in G1 R-HSA-69231 2.734217e-02 1.563 0 0
Interferon alpha/beta signaling R-HSA-909733 2.742206e-02 1.562 0 0
Basigin interactions R-HSA-210991 2.766482e-02 1.558 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 2.766482e-02 1.558 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.766482e-02 1.558 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 2.829379e-02 1.548 0 0
Chromatin organization R-HSA-4839726 2.831533e-02 1.548 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.846254e-02 1.546 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 2.846254e-02 1.546 0 0
MTF1 activates gene expression R-HSA-5660489 2.846254e-02 1.546 0 0
Signaling by NOTCH4 R-HSA-9013694 2.853526e-02 1.545 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 2.883863e-02 1.540 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 2.959408e-02 1.529 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.959408e-02 1.529 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 2.959408e-02 1.529 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 2.959408e-02 1.529 0 0
Response of endothelial cells to shear stress R-HSA-9860931 3.076571e-02 1.512 0 0
Opioid Signalling R-HSA-111885 3.076571e-02 1.512 0 0
Downstream TCR signaling R-HSA-202424 3.091016e-02 1.510 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.162819e-02 1.500 0 0
Vpu mediated degradation of CD4 R-HSA-180534 3.162819e-02 1.500 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 3.196436e-02 1.495 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.196436e-02 1.495 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 3.232883e-02 1.490 0 0
Activation of HOX genes during differentiation R-HSA-5619507 3.232883e-02 1.490 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 3.394691e-02 1.469 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 3.445484e-02 1.463 0 0
Dual Incision in GG-NER R-HSA-5696400 3.458094e-02 1.461 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 3.458094e-02 1.461 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 3.458094e-02 1.461 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 3.458094e-02 1.461 0 0
PCP/CE pathway R-HSA-4086400 3.613170e-02 1.442 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 3.766587e-02 1.424 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 3.766587e-02 1.424 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 3.766587e-02 1.424 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 3.769882e-02 1.424 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 3.769882e-02 1.424 0 0
Signalling to ERKs R-HSA-187687 3.769882e-02 1.424 0 0
Formation of axial mesoderm R-HSA-9796292 3.869497e-02 1.412 0 0
Syndecan interactions R-HSA-3000170 3.878025e-02 1.411 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 3.913887e-02 1.407 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 3.924569e-02 1.406 0 0
DNA Damage Bypass R-HSA-73893 3.980303e-02 1.400 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 4.098341e-02 1.387 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 4.098463e-02 1.387 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 4.242124e-02 1.372 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 4.242124e-02 1.372 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 8.304539e-02 1.081 0 0
Diseases of Telomere Maintenance R-HSA-9673013 8.304539e-02 1.081 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 8.304539e-02 1.081 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 8.304539e-02 1.081 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 8.304539e-02 1.081 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 8.304539e-02 1.081 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 8.304539e-02 1.081 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 8.304539e-02 1.081 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 8.304539e-02 1.081 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 8.304539e-02 1.081 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 8.304539e-02 1.081 0 0
Hereditary fructose intolerance R-HSA-5657560 8.304539e-02 1.081 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 4.783645e-02 1.320 0 0
Phosphorylation of Emi1 R-HSA-176417 4.783645e-02 1.320 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 5.887591e-02 1.230 0 0
SOS-mediated signalling R-HSA-112412 7.069245e-02 1.151 0 0
Disinhibition of SNARE formation R-HSA-114516 7.069245e-02 1.151 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 5.740967e-02 1.241 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 7.184418e-02 1.144 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 5.200453e-02 1.284 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 6.249932e-02 1.204 0 0
snRNP Assembly R-HSA-191859 7.415518e-02 1.130 0 0
Metabolism of non-coding RNA R-HSA-194441 7.415518e-02 1.130 0 0
PTEN Regulation R-HSA-6807070 4.251194e-02 1.371 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 5.515689e-02 1.258 0 0
Regulation of PTEN stability and activity R-HSA-8948751 5.200453e-02 1.284 0 0
PKMTs methylate histone lysines R-HSA-3214841 5.993919e-02 1.222 0 0
Nucleotide Excision Repair R-HSA-5696398 7.213295e-02 1.142 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 5.887591e-02 1.230 0 0
Mitotic Spindle Checkpoint R-HSA-69618 5.583666e-02 1.253 0 0
DCC mediated attractive signaling R-HSA-418885 5.076834e-02 1.294 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 5.993919e-02 1.222 0 0
p38MAPK events R-HSA-171007 5.076834e-02 1.294 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.266360e-02 1.370 0 0
Myogenesis R-HSA-525793 5.209963e-02 1.283 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.076834e-02 1.294 0 0
Orc1 removal from chromatin R-HSA-68949 4.876345e-02 1.312 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 6.234992e-02 1.205 0 0
Peroxisomal protein import R-HSA-9033241 7.415518e-02 1.130 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 4.596281e-02 1.338 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.783645e-02 1.320 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 4.452671e-02 1.351 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 5.076834e-02 1.294 0 0
Termination of translesion DNA synthesis R-HSA-5656169 6.760208e-02 1.170 0 0
Degradation of CRY and PER proteins R-HSA-9932298 6.423876e-02 1.192 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 4.214017e-02 1.375 0 0
Protein localization R-HSA-9609507 7.313194e-02 1.136 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 4.783645e-02 1.320 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.565367e-02 1.183 0 0
Signaling by TGFB family members R-HSA-9006936 5.008564e-02 1.300 0 0
Degradation of DVL R-HSA-4641258 4.443597e-02 1.352 0 0
Inhibition of PKR R-HSA-169131 8.304539e-02 1.081 0 0
Degradation of AXIN R-HSA-4641257 4.443597e-02 1.352 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 4.443597e-02 1.352 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 4.443597e-02 1.352 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 6.423876e-02 1.192 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 6.788193e-02 1.168 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 6.788193e-02 1.168 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.603032e-02 1.119 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.603032e-02 1.119 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 5.110745e-02 1.292 0 0
Pentose phosphate pathway R-HSA-71336 5.184830e-02 1.285 0 0
Malate-aspartate shuttle R-HSA-9856872 4.452671e-02 1.351 0 0
CHL1 interactions R-HSA-447041 7.069245e-02 1.151 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 6.423876e-02 1.192 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 6.423876e-02 1.192 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 4.642373e-02 1.333 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 7.069245e-02 1.151 0 0
Platelet calcium homeostasis R-HSA-418360 6.760208e-02 1.170 0 0
DNA Repair R-HSA-73894 7.175875e-02 1.144 0 0
Regulation of TP53 Activity R-HSA-5633007 5.008564e-02 1.300 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 4.288914e-02 1.368 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.297504e-02 1.367 0 0
MyD88-independent TLR4 cascade R-HSA-166166 4.288914e-02 1.368 0 0
TNF signaling R-HSA-75893 6.249932e-02 1.204 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 8.256794e-02 1.083 0 0
Cardiac conduction R-HSA-5576891 5.907358e-02 1.229 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.605305e-02 1.251 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 4.896163e-02 1.310 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 5.558481e-02 1.255 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 5.580891e-02 1.253 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 5.993919e-02 1.222 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 5.209963e-02 1.283 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 5.702715e-02 1.244 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 5.702715e-02 1.244 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 5.993919e-02 1.222 0 0
Nef and signal transduction R-HSA-164944 5.887591e-02 1.230 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.876345e-02 1.312 0 0
Interleukin-7 signaling R-HSA-1266695 4.741510e-02 1.324 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 5.791083e-02 1.237 0 0
Signaling by NOTCH3 R-HSA-9012852 5.887211e-02 1.230 0 0
Apoptotic factor-mediated response R-HSA-111471 7.961101e-02 1.099 0 0
Base Excision Repair R-HSA-73884 6.978541e-02 1.156 0 0
Suppression of phagosomal maturation R-HSA-9637687 5.209963e-02 1.283 0 0
Glycogen metabolism R-HSA-8982491 5.580891e-02 1.253 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 7.297020e-02 1.137 0 0
Ion channel transport R-HSA-983712 7.334533e-02 1.135 0 0
Regulation of gene expression in beta cells R-HSA-210745 6.760208e-02 1.170 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 6.219553e-02 1.206 0 0
Metabolism of amino acids and derivatives R-HSA-71291 6.941463e-02 1.159 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 8.311195e-02 1.080 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 8.311195e-02 1.080 0 0
Formation of annular gap junctions R-HSA-196025 8.320049e-02 1.080 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 8.320049e-02 1.080 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 8.320049e-02 1.080 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 8.320049e-02 1.080 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 8.586202e-02 1.066 0 0
tRNA processing in the nucleus R-HSA-6784531 8.696519e-02 1.061 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 8.772516e-02 1.057 0 0
Rap1 signalling R-HSA-392517 8.772516e-02 1.057 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 8.824200e-02 1.054 0 0
Regulation of TNFR1 signaling R-HSA-5357905 8.824200e-02 1.054 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 9.153648e-02 1.038 0 0
Integrin signaling R-HSA-354192 9.153648e-02 1.038 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 9.153648e-02 1.038 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.353301e-02 1.029 0 0
Inositol phosphate metabolism R-HSA-1483249 9.451694e-02 1.024 0 0
Clathrin-mediated endocytosis R-HSA-8856828 9.594767e-02 1.018 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 9.617148e-02 1.017 0 0
Gap junction degradation R-HSA-190873 9.632028e-02 1.016 0 0
Hypusine synthesis from eIF5A-lysine R-HSA-204626 9.632028e-02 1.016 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 9.632028e-02 1.016 0 0
ARMS-mediated activation R-HSA-170984 9.632028e-02 1.016 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 9.632028e-02 1.016 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 9.632028e-02 1.016 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 9.632028e-02 1.016 0 0
PIP3 activates AKT signaling R-HSA-1257604 9.698059e-02 1.013 0 0
Effects of PIP2 hydrolysis R-HSA-114508 9.807453e-02 1.008 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 9.807453e-02 1.008 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 1.045885e-01 0.981 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 1.048238e-01 0.980 0 0
Calnexin/calreticulin cycle R-HSA-901042 1.048238e-01 0.980 0 0
Signaling by NOTCH2 R-HSA-1980145 1.048238e-01 0.980 0 0
Mitophagy R-HSA-5205647 1.048238e-01 0.980 0 0
Signalling to RAS R-HSA-167044 1.049343e-01 0.979 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.099776e-01 0.959 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.099776e-01 0.959 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 1.099776e-01 0.959 0 0
Ribavirin ADME R-HSA-9755088 1.139975e-01 0.943 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 1.162571e-01 0.935 0 0
Post-translational protein modification R-HSA-597592 1.165981e-01 0.933 0 0
Interleukin-1 signaling R-HSA-9020702 1.179112e-01 0.928 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.186156e-01 0.926 0 0
RET signaling R-HSA-8853659 1.189321e-01 0.925 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.212053e-01 0.916 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 1.219485e-01 0.914 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 1.219485e-01 0.914 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 1.219485e-01 0.914 0 0
Loss of Function of SMAD4 in Cancer R-HSA-3304347 1.219485e-01 0.914 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 1.219485e-01 0.914 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 1.219485e-01 0.914 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 1.219485e-01 0.914 0 0
SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-3315487 1.219485e-01 0.914 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 1.219485e-01 0.914 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 1.219485e-01 0.914 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 1.219485e-01 0.914 0 0
SMAD4 MH2 Domain Mutants in Cancer R-HSA-3311021 1.219485e-01 0.914 0 0
Oligomerization of connexins into connexons R-HSA-190704 1.219485e-01 0.914 0 0
ARL13B-mediated ciliary trafficking of INPP5E R-HSA-5624958 1.219485e-01 0.914 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.219485e-01 0.914 0 0
Transport of connexins along the secretory pathway R-HSA-190827 1.219485e-01 0.914 0 0
NTRK3 as a dependence receptor R-HSA-9603505 1.219485e-01 0.914 0 0
mRNA 3'-end processing R-HSA-72187 1.223138e-01 0.913 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 1.241033e-01 0.906 0 0
ChREBP activates metabolic gene expression R-HSA-163765 1.241033e-01 0.906 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 1.265728e-01 0.898 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.265728e-01 0.898 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.283983e-01 0.891 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 1.285913e-01 0.891 0 0
Hedgehog 'on' state R-HSA-5632684 1.320538e-01 0.879 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 1.329592e-01 0.876 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.386334e-01 0.858 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.386334e-01 0.858 0 0
Integration of provirus R-HSA-162592 1.386334e-01 0.858 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.386334e-01 0.858 0 0
Plasma lipoprotein clearance R-HSA-8964043 1.415209e-01 0.849 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 1.428243e-01 0.845 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.428243e-01 0.845 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 1.433475e-01 0.844 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.451811e-01 0.838 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 1.479428e-01 0.830 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.494030e-01 0.826 0 0
Generation of second messenger molecules R-HSA-202433 1.494030e-01 0.826 0 0
HDMs demethylate histones R-HSA-3214842 1.529234e-01 0.816 0 0
Tight junction interactions R-HSA-420029 1.529234e-01 0.816 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.529234e-01 0.816 0 0
IRE1alpha activates chaperones R-HSA-381070 1.530091e-01 0.815 0 0
GRB2 events in EGFR signaling R-HSA-179812 1.535081e-01 0.814 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 1.535081e-01 0.814 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 1.535081e-01 0.814 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.535081e-01 0.814 0 0
OAS antiviral response R-HSA-8983711 1.535081e-01 0.814 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.550678e-01 0.809 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 1.590166e-01 0.799 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 1.590166e-01 0.799 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 1.590166e-01 0.799 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.592033e-01 0.798 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.592033e-01 0.798 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 1.592033e-01 0.798 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 1.592033e-01 0.798 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 1.592033e-01 0.798 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 1.592033e-01 0.798 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 1.592033e-01 0.798 0 0
Neurophilin interactions with VEGF and VEGFR R-HSA-194306 1.592033e-01 0.798 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 1.592033e-01 0.798 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 1.592033e-01 0.798 0 0
Dual incision in TC-NER R-HSA-6782135 1.615455e-01 0.792 0 0
Translation of Structural Proteins R-HSA-9683701 1.656522e-01 0.781 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.686722e-01 0.773 0 0
Frs2-mediated activation R-HSA-170968 1.686722e-01 0.773 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 1.686722e-01 0.773 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 1.686722e-01 0.773 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.686722e-01 0.773 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.689829e-01 0.772 0 0
Mitochondrial protein degradation R-HSA-9837999 1.693510e-01 0.771 0 0
ABC transporter disorders R-HSA-5619084 1.734036e-01 0.761 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 1.737567e-01 0.760 0 0
Cristae formation R-HSA-8949613 1.737567e-01 0.760 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.756297e-01 0.755 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.828416e-01 0.738 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.828416e-01 0.738 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.840746e-01 0.735 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.840746e-01 0.735 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 1.840746e-01 0.735 0 0
Regulation of KIT signaling R-HSA-1433559 1.840746e-01 0.735 0 0
Telomere Extension By Telomerase R-HSA-171319 1.844579e-01 0.734 0 0
Pyroptosis R-HSA-5620971 1.844579e-01 0.734 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.860993e-01 0.730 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.888595e-01 0.724 0 0
Mitochondrial protein import R-HSA-1268020 1.901606e-01 0.721 0 0
Netrin-1 signaling R-HSA-373752 1.911237e-01 0.719 0 0
FasL/ CD95L signaling R-HSA-75157 1.948796e-01 0.710 0 0
Classical Kir channels R-HSA-1296053 1.948796e-01 0.710 0 0
MET interacts with TNS proteins R-HSA-8875513 1.948796e-01 0.710 0 0
Intracellular oxygen transport R-HSA-8981607 1.948796e-01 0.710 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 1.953271e-01 0.709 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.975823e-01 0.704 0 0
Erythropoietin activates RAS R-HSA-9027284 1.996677e-01 0.700 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.996677e-01 0.700 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.996677e-01 0.700 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 1.996677e-01 0.700 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.998758e-01 0.699 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.998758e-01 0.699 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 1.998758e-01 0.699 0 0
FOXO-mediated transcription R-HSA-9614085 2.041607e-01 0.690 0 0
Interleukin-1 family signaling R-HSA-446652 2.078147e-01 0.682 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 2.087458e-01 0.680 0 0
Cellular response to hypoxia R-HSA-1234174 2.127147e-01 0.672 0 0
Prolonged ERK activation events R-HSA-169893 2.154078e-01 0.667 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 2.154078e-01 0.667 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.154078e-01 0.667 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 2.179822e-01 0.662 0 0
Asparagine N-linked glycosylation R-HSA-446203 2.180181e-01 0.662 0 0
Diseases of mitotic cell cycle R-HSA-9675126 2.287849e-01 0.641 0 0
G0 and Early G1 R-HSA-1538133 2.287849e-01 0.641 0 0
HCN channels R-HSA-1296061 2.290442e-01 0.640 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 2.290442e-01 0.640 0 0
Nucleotide catabolism defects R-HSA-9735786 2.290442e-01 0.640 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.290442e-01 0.640 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.290442e-01 0.640 0 0
NADE modulates death signalling R-HSA-205025 2.290442e-01 0.640 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.290442e-01 0.640 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.290442e-01 0.640 0 0
Dopamine receptors R-HSA-390651 2.290442e-01 0.640 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 2.312544e-01 0.636 0 0
Galactose catabolism R-HSA-70370 2.312544e-01 0.636 0 0
Response to metal ions R-HSA-5660526 2.312544e-01 0.636 0 0
XBP1(S) activates chaperone genes R-HSA-381038 2.331317e-01 0.632 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 2.359837e-01 0.627 0 0
RSV-host interactions R-HSA-9833110 2.414233e-01 0.617 0 0
Parasite infection R-HSA-9664407 2.451595e-01 0.611 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 2.451595e-01 0.611 0 0
Leishmania phagocytosis R-HSA-9664417 2.451595e-01 0.611 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 2.471702e-01 0.607 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 2.471702e-01 0.607 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 2.516469e-01 0.599 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 2.516469e-01 0.599 0 0
ER-Phagosome pathway R-HSA-1236974 2.543362e-01 0.595 0 0
Synthesis of DNA R-HSA-69239 2.608195e-01 0.584 0 0
IRS activation R-HSA-74713 2.617610e-01 0.582 0 0
G2 Phase R-HSA-68911 2.617610e-01 0.582 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.617610e-01 0.582 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.617610e-01 0.582 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.617610e-01 0.582 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 2.617610e-01 0.582 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 2.617610e-01 0.582 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 2.617610e-01 0.582 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.617610e-01 0.582 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 2.631208e-01 0.580 0 0
GAB1 signalosome R-HSA-180292 2.631208e-01 0.580 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.631208e-01 0.580 0 0
Presynaptic function of Kainate receptors R-HSA-500657 2.631208e-01 0.580 0 0
Nephron development R-HSA-9831926 2.631208e-01 0.580 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 2.631208e-01 0.580 0 0
Signal amplification R-HSA-392518 2.632013e-01 0.580 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 2.640006e-01 0.578 0 0
G1/S Transition R-HSA-69206 2.649263e-01 0.577 0 0
Extracellular matrix organization R-HSA-1474244 2.678385e-01 0.572 0 0
PERK regulates gene expression R-HSA-381042 2.748196e-01 0.561 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.764040e-01 0.558 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.790748e-01 0.554 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.790748e-01 0.554 0 0
The NLRP3 inflammasome R-HSA-844456 2.790748e-01 0.554 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 2.790748e-01 0.554 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 2.790748e-01 0.554 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.845855e-01 0.546 0 0
Iron uptake and transport R-HSA-917937 2.929252e-01 0.533 0 0
Plus-strand DNA synthesis R-HSA-164525 2.930914e-01 0.533 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.930914e-01 0.533 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.930914e-01 0.533 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.930914e-01 0.533 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.930914e-01 0.533 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.930914e-01 0.533 0 0
Pentose phosphate pathway disease R-HSA-6791465 2.930914e-01 0.533 0 0
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399 2.930914e-01 0.533 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.930914e-01 0.533 0 0
VEGF ligand-receptor interactions R-HSA-194313 2.930914e-01 0.533 0 0
Acetylcholine inhibits contraction of outer hair cells R-HSA-9667769 2.930914e-01 0.533 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 2.930914e-01 0.533 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.930914e-01 0.533 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 2.950032e-01 0.530 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.950032e-01 0.530 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.950032e-01 0.530 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.950032e-01 0.530 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 3.067742e-01 0.513 0 0
Translation of Structural Proteins R-HSA-9694635 3.096103e-01 0.509 0 0
MET promotes cell motility R-HSA-8875878 3.099277e-01 0.509 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 3.108795e-01 0.507 0 0
Early Phase of HIV Life Cycle R-HSA-162594 3.108795e-01 0.507 0 0
ERK/MAPK targets R-HSA-198753 3.108795e-01 0.507 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.108795e-01 0.507 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 3.180028e-01 0.498 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 3.216738e-01 0.493 0 0
Signaling by LTK in cancer R-HSA-9842640 3.230939e-01 0.491 0 0
Erythropoietin activates STAT5 R-HSA-9027283 3.230939e-01 0.491 0 0
Uncoating of the HIV Virion R-HSA-162585 3.230939e-01 0.491 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.230939e-01 0.491 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 3.230939e-01 0.491 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 3.230939e-01 0.491 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 3.230939e-01 0.491 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.230939e-01 0.491 0 0
CREB phosphorylation R-HSA-199920 3.230939e-01 0.491 0 0
VLDL assembly R-HSA-8866423 3.230939e-01 0.491 0 0
Signaling by PDGFR in disease R-HSA-9671555 3.266794e-01 0.486 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.266794e-01 0.486 0 0
Parasitic Infection Pathways R-HSA-9824443 3.287604e-01 0.483 0 0
Leishmania infection R-HSA-9658195 3.287604e-01 0.483 0 0
Regulation of beta-cell development R-HSA-186712 3.312663e-01 0.480 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 3.315291e-01 0.479 0 0
RAB geranylgeranylation R-HSA-8873719 3.409882e-01 0.467 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 3.409882e-01 0.467 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 3.409882e-01 0.467 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 3.409882e-01 0.467 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 3.409882e-01 0.467 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 3.409882e-01 0.467 0 0
FGFR2 alternative splicing R-HSA-6803529 3.423809e-01 0.465 0 0
Fructose metabolism R-HSA-5652084 3.423809e-01 0.465 0 0
Integration of energy metabolism R-HSA-163685 3.463632e-01 0.460 0 0
ABC-family proteins mediated transport R-HSA-382556 3.508715e-01 0.455 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 3.518248e-01 0.454 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 3.518248e-01 0.454 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.518248e-01 0.454 0 0
DAG1 core M1 glycosylations R-HSA-8932506 3.518248e-01 0.454 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.518248e-01 0.454 0 0
Recycling of eIF2:GDP R-HSA-72731 3.518248e-01 0.454 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.518248e-01 0.454 0 0
PTK6 Expression R-HSA-8849473 3.518248e-01 0.454 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 3.518248e-01 0.454 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.518248e-01 0.454 0 0
LDL remodeling R-HSA-8964041 3.518248e-01 0.454 0 0
Ca2+ activated K+ channels R-HSA-1296052 3.518248e-01 0.454 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 3.518248e-01 0.454 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 3.518248e-01 0.454 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 3.579639e-01 0.446 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 3.579639e-01 0.446 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.579639e-01 0.446 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 3.584808e-01 0.446 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 3.602869e-01 0.443 0 0
Activation of GABAB receptors R-HSA-991365 3.685748e-01 0.433 0 0
GABA B receptor activation R-HSA-977444 3.685748e-01 0.433 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 3.695546e-01 0.432 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 3.734103e-01 0.428 0 0
Complex III assembly R-HSA-9865881 3.734103e-01 0.428 0 0
Reverse Transcription of HIV RNA R-HSA-162589 3.793379e-01 0.421 0 0
Minus-strand DNA synthesis R-HSA-164516 3.793379e-01 0.421 0 0
Type I hemidesmosome assembly R-HSA-446107 3.793379e-01 0.421 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.793379e-01 0.421 0 0
DAG1 core M2 glycosylations R-HSA-8932504 3.793379e-01 0.421 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 3.793379e-01 0.421 0 0
Regulation by c-FLIP R-HSA-3371378 3.793379e-01 0.421 0 0
Activation of RAS in B cells R-HSA-1169092 3.793379e-01 0.421 0 0
Fructose biosynthesis R-HSA-5652227 3.793379e-01 0.421 0 0
FGFR1b ligand binding and activation R-HSA-190370 3.793379e-01 0.421 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.793379e-01 0.421 0 0
Dimerization of procaspase-8 R-HSA-69416 3.793379e-01 0.421 0 0
Sodium/Proton exchangers R-HSA-425986 3.793379e-01 0.421 0 0
Interleukin-23 signaling R-HSA-9020933 3.793379e-01 0.421 0 0
Signaling by SCF-KIT R-HSA-1433557 3.802283e-01 0.420 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 3.813594e-01 0.419 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 3.857606e-01 0.414 0 0
Innate Immune System R-HSA-168249 3.865547e-01 0.413 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.887035e-01 0.410 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.887035e-01 0.410 0 0
G protein gated Potassium channels R-HSA-1296059 3.887035e-01 0.410 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 3.887035e-01 0.410 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 3.887035e-01 0.410 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 3.887035e-01 0.410 0 0
Hyaluronan degradation R-HSA-2160916 3.887035e-01 0.410 0 0
Formation of the cornified envelope R-HSA-6809371 3.907510e-01 0.408 0 0
Proteasome assembly R-HSA-9907900 3.918344e-01 0.407 0 0
MET activates PTK2 signaling R-HSA-8874081 4.038288e-01 0.394 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 4.038288e-01 0.394 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 4.038288e-01 0.394 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 4.038288e-01 0.394 0 0
Platelet homeostasis R-HSA-418346 4.042517e-01 0.393 0 0
Lipophagy R-HSA-9613354 4.056848e-01 0.392 0 0
CASP8 activity is inhibited R-HSA-5218900 4.056848e-01 0.392 0 0
ALK mutants bind TKIs R-HSA-9700645 4.056848e-01 0.392 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 4.056848e-01 0.392 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 4.056848e-01 0.392 0 0
Calcineurin activates NFAT R-HSA-2025928 4.056848e-01 0.392 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 4.056848e-01 0.392 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 4.056848e-01 0.392 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 4.056848e-01 0.392 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 4.056848e-01 0.392 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 4.056848e-01 0.392 0 0
Cellular response to mitochondrial stress R-HSA-9840373 4.056848e-01 0.392 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 4.056848e-01 0.392 0 0
Kidney development R-HSA-9830369 4.089321e-01 0.388 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 4.089321e-01 0.388 0 0
Signaling by TGFBR3 R-HSA-9839373 4.148705e-01 0.382 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 4.148705e-01 0.382 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 4.187729e-01 0.378 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 4.187729e-01 0.378 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 4.187729e-01 0.378 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 4.187729e-01 0.378 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 4.187729e-01 0.378 0 0
Antigen processing-Cross presentation R-HSA-1236975 4.194830e-01 0.377 0 0
Stimuli-sensing channels R-HSA-2672351 4.194830e-01 0.377 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 4.256832e-01 0.371 0 0
Toll-like Receptor Cascades R-HSA-168898 4.262012e-01 0.370 0 0
S Phase R-HSA-69242 4.305292e-01 0.366 0 0
Signaling by NTRKs R-HSA-166520 4.305292e-01 0.366 0 0
Binding and entry of HIV virion R-HSA-173107 4.309148e-01 0.366 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 4.309148e-01 0.366 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.309148e-01 0.366 0 0
PI3K/AKT activation R-HSA-198203 4.309148e-01 0.366 0 0
2-LTR circle formation R-HSA-164843 4.309148e-01 0.366 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 4.309148e-01 0.366 0 0
Signal attenuation R-HSA-74749 4.309148e-01 0.366 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 4.309148e-01 0.366 0 0
MAPK3 (ERK1) activation R-HSA-110056 4.309148e-01 0.366 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 4.309148e-01 0.366 0 0
Signaling by Leptin R-HSA-2586552 4.309148e-01 0.366 0 0
HIV elongation arrest and recovery R-HSA-167287 4.335240e-01 0.363 0 0
Pausing and recovery of HIV elongation R-HSA-167290 4.335240e-01 0.363 0 0
Inflammasomes R-HSA-622312 4.335240e-01 0.363 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 4.335240e-01 0.363 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 4.335240e-01 0.363 0 0
GPER1 signaling R-HSA-9634597 4.376201e-01 0.359 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 4.396055e-01 0.357 0 0
Potential therapeutics for SARS R-HSA-9679191 4.434635e-01 0.353 0 0
ECM proteoglycans R-HSA-3000178 4.471817e-01 0.350 0 0
Signaling by Erythropoietin R-HSA-9006335 4.480715e-01 0.349 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 4.531498e-01 0.344 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 4.531498e-01 0.344 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.550752e-01 0.342 0 0
DAG1 core M3 glycosylations R-HSA-8932505 4.550752e-01 0.342 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 4.550752e-01 0.342 0 0
vRNP Assembly R-HSA-192905 4.550752e-01 0.342 0 0
Chylomicron assembly R-HSA-8963888 4.550752e-01 0.342 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 4.550752e-01 0.342 0 0
Bicarbonate transporters R-HSA-425381 4.550752e-01 0.342 0 0
PECAM1 interactions R-HSA-210990 4.550752e-01 0.342 0 0
Interleukin-2 signaling R-HSA-9020558 4.550752e-01 0.342 0 0
Dissolution of Fibrin Clot R-HSA-75205 4.550752e-01 0.342 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 4.563557e-01 0.341 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 4.566290e-01 0.340 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 4.624062e-01 0.335 0 0
DAP12 signaling R-HSA-2424491 4.624062e-01 0.335 0 0
Interleukin-37 signaling R-HSA-9008059 4.624062e-01 0.335 0 0
Death Receptor Signaling R-HSA-73887 4.691932e-01 0.329 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 4.697223e-01 0.328 0 0
The phototransduction cascade R-HSA-2514856 4.710864e-01 0.327 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 4.765199e-01 0.322 0 0
Molecules associated with elastic fibres R-HSA-2129379 4.765199e-01 0.322 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 4.782112e-01 0.320 0 0
Signaling by GSK3beta mutants R-HSA-5339716 4.782112e-01 0.320 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.782112e-01 0.320 0 0
Plasmalogen biosynthesis R-HSA-75896 4.782112e-01 0.320 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.782112e-01 0.320 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 4.782112e-01 0.320 0 0
Activation of RAC1 R-HSA-428540 4.782112e-01 0.320 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 4.782112e-01 0.320 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 4.820420e-01 0.317 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 4.846265e-01 0.315 0 0
Disorders of transmembrane transporters R-HSA-5619115 4.894140e-01 0.310 0 0
Inwardly rectifying K+ channels R-HSA-1296065 4.904055e-01 0.309 0 0
Signaling by NOTCH1 R-HSA-1980143 4.938313e-01 0.306 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 5.003663e-01 0.301 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 5.003663e-01 0.301 0 0
Scavenging by Class F Receptors R-HSA-3000484 5.003663e-01 0.301 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 5.003663e-01 0.301 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 5.003663e-01 0.301 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 5.003663e-01 0.301 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 5.003663e-01 0.301 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 5.003663e-01 0.301 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 5.003663e-01 0.301 0 0
MET activates RAS signaling R-HSA-8851805 5.003663e-01 0.301 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 5.003663e-01 0.301 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 5.003663e-01 0.301 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 5.003663e-01 0.301 0 0
Rab regulation of trafficking R-HSA-9007101 5.018392e-01 0.299 0 0
Mitochondrial biogenesis R-HSA-1592230 5.018392e-01 0.299 0 0
G-protein beta:gamma signalling R-HSA-397795 5.040570e-01 0.298 0 0
Nuclear RNA decay R-HSA-9930044 5.040570e-01 0.298 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 5.040570e-01 0.298 0 0
Activation of ATR in response to replication stress R-HSA-176187 5.040570e-01 0.298 0 0
Regulation of insulin secretion R-HSA-422356 5.104056e-01 0.292 0 0
Integrin cell surface interactions R-HSA-216083 5.120285e-01 0.291 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 5.183929e-01 0.285 0 0
PDH complex synthesizes acetyl-CoA from PYR R-HSA-9861559 5.215821e-01 0.283 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 5.215821e-01 0.283 0 0
Processing of SMDT1 R-HSA-8949664 5.215821e-01 0.283 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 5.215821e-01 0.283 0 0
Diseases of nucleotide metabolism R-HSA-9735804 5.215821e-01 0.283 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 5.215821e-01 0.283 0 0
FGFR1c ligand binding and activation R-HSA-190373 5.215821e-01 0.283 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 5.215821e-01 0.283 0 0
CD28 dependent Vav1 pathway R-HSA-389359 5.215821e-01 0.283 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 5.215821e-01 0.283 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 5.215821e-01 0.283 0 0
Interleukin-6 signaling R-HSA-1059683 5.215821e-01 0.283 0 0
Hyaluronan metabolism R-HSA-2142845 5.306380e-01 0.275 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 5.306380e-01 0.275 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 5.308060e-01 0.275 0 0
CRMPs in Sema3A signaling R-HSA-399956 5.418981e-01 0.266 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 5.418981e-01 0.266 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 5.418981e-01 0.266 0 0
Signal regulatory protein family interactions R-HSA-391160 5.418981e-01 0.266 0 0
Signaling by FGFR4 in disease R-HSA-5655291 5.418981e-01 0.266 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.450260e-01 0.264 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 5.479355e-01 0.261 0 0
FCERI mediated NF-kB activation R-HSA-2871837 5.543365e-01 0.256 0 0
Extension of Telomeres R-HSA-180786 5.554388e-01 0.255 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 5.562315e-01 0.255 0 0
G1/S-Specific Transcription R-HSA-69205 5.562315e-01 0.255 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 5.613527e-01 0.251 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.613527e-01 0.251 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.613527e-01 0.251 0 0
G beta:gamma signalling through BTK R-HSA-8964315 5.613527e-01 0.251 0 0
Signaling by Activin R-HSA-1502540 5.613527e-01 0.251 0 0
Protein lipoylation R-HSA-9857492 5.613527e-01 0.251 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.613527e-01 0.251 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 5.613527e-01 0.251 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 5.613527e-01 0.251 0 0
Other semaphorin interactions R-HSA-416700 5.613527e-01 0.251 0 0
GABA receptor activation R-HSA-977443 5.654082e-01 0.248 0 0
tRNA processing R-HSA-72306 5.745140e-01 0.241 0 0
G alpha (q) signalling events R-HSA-416476 5.746854e-01 0.241 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.799821e-01 0.237 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 5.799821e-01 0.237 0 0
Phosphorylation of the APC/C R-HSA-176412 5.799821e-01 0.237 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.799821e-01 0.237 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.799821e-01 0.237 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 5.799821e-01 0.237 0 0
Fructose catabolism R-HSA-70350 5.799821e-01 0.237 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.799821e-01 0.237 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.799821e-01 0.237 0 0
Activation of SMO R-HSA-5635838 5.799821e-01 0.237 0 0
Attachment and Entry R-HSA-9678110 5.799821e-01 0.237 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 5.808180e-01 0.236 0 0
Elastic fibre formation R-HSA-1566948 5.808180e-01 0.236 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 5.808180e-01 0.236 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 5.808180e-01 0.236 0 0
NCAM signaling for neurite out-growth R-HSA-375165 5.849311e-01 0.233 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 5.898382e-01 0.229 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 5.927304e-01 0.227 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 5.927304e-01 0.227 0 0
Signaling by ALK R-HSA-201556 5.927304e-01 0.227 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 5.978215e-01 0.223 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 5.978215e-01 0.223 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 5.978215e-01 0.223 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 5.978215e-01 0.223 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.978215e-01 0.223 0 0
Fibronectin matrix formation R-HSA-1566977 5.978215e-01 0.223 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 5.978215e-01 0.223 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 5.978215e-01 0.223 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.978215e-01 0.223 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 6.043881e-01 0.219 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 6.043881e-01 0.219 0 0
HIV Transcription Elongation R-HSA-167169 6.043881e-01 0.219 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 6.043881e-01 0.219 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 6.149042e-01 0.211 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 6.149042e-01 0.211 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 6.149042e-01 0.211 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 6.157914e-01 0.211 0 0
Circadian clock R-HSA-9909396 6.194814e-01 0.208 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 6.269408e-01 0.203 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 6.312623e-01 0.200 0 0
FGFR1 ligand binding and activation R-HSA-190242 6.312623e-01 0.200 0 0
Platelet sensitization by LDL R-HSA-432142 6.312623e-01 0.200 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 6.312623e-01 0.200 0 0
Tie2 Signaling R-HSA-210993 6.312623e-01 0.200 0 0
Polo-like kinase mediated events R-HSA-156711 6.312623e-01 0.200 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 6.312623e-01 0.200 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.312623e-01 0.200 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 6.378373e-01 0.195 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 6.378373e-01 0.195 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 6.378373e-01 0.195 0 0
Interferon gamma signaling R-HSA-877300 6.461997e-01 0.190 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 6.469265e-01 0.189 0 0
Specification of the neural plate border R-HSA-9834899 6.469265e-01 0.189 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 6.469265e-01 0.189 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.469265e-01 0.189 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.469265e-01 0.189 0 0
TBC/RABGAPs R-HSA-8854214 6.484823e-01 0.188 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 6.575525e-01 0.182 0 0
DAP12 interactions R-HSA-2172127 6.588775e-01 0.181 0 0
Signaling by NODAL R-HSA-1181150 6.619262e-01 0.179 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 6.619262e-01 0.179 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 6.619262e-01 0.179 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.619262e-01 0.179 0 0
Creatine metabolism R-HSA-71288 6.619262e-01 0.179 0 0
Pregnenolone biosynthesis R-HSA-196108 6.619262e-01 0.179 0 0
Protein hydroxylation R-HSA-9629569 6.619262e-01 0.179 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 6.690248e-01 0.175 0 0
Somitogenesis R-HSA-9824272 6.690248e-01 0.175 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 6.738183e-01 0.171 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 6.738183e-01 0.171 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 6.762895e-01 0.170 0 0
G-protein activation R-HSA-202040 6.762895e-01 0.170 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 6.762895e-01 0.170 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 6.762895e-01 0.170 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 6.762895e-01 0.170 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 6.762895e-01 0.170 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 6.789266e-01 0.168 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 6.789266e-01 0.168 0 0
Potassium Channels R-HSA-1296071 6.813308e-01 0.167 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 6.900435e-01 0.161 0 0
Mitochondrial calcium ion transport R-HSA-8949215 6.900435e-01 0.161 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 6.900435e-01 0.161 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 6.900435e-01 0.161 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.900435e-01 0.161 0 0
Attachment and Entry R-HSA-9694614 6.900435e-01 0.161 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 6.945263e-01 0.158 0 0
Post-translational protein phosphorylation R-HSA-8957275 6.951015e-01 0.158 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 6.975799e-01 0.156 0 0
Co-stimulation by CD28 R-HSA-389356 6.980040e-01 0.156 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 7.032138e-01 0.153 0 0
Ethanol oxidation R-HSA-71384 7.032138e-01 0.153 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 7.032138e-01 0.153 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 7.032138e-01 0.153 0 0
Signaling by KIT in disease R-HSA-9669938 7.032138e-01 0.153 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 7.032138e-01 0.153 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 7.126781e-01 0.147 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 7.158253e-01 0.145 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 7.158253e-01 0.145 0 0
Biosynthesis of maresins R-HSA-9018682 7.158253e-01 0.145 0 0
Formation of the ureteric bud R-HSA-9830674 7.158253e-01 0.145 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 7.158253e-01 0.145 0 0
Growth hormone receptor signaling R-HSA-982772 7.158253e-01 0.145 0 0
Azathioprine ADME R-HSA-9748787 7.161325e-01 0.145 0 0
Neddylation R-HSA-8951664 7.170275e-01 0.144 0 0
Leishmania parasite growth and survival R-HSA-9664433 7.259640e-01 0.139 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 7.259640e-01 0.139 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 7.271885e-01 0.138 0 0
CYP2E1 reactions R-HSA-211999 7.279016e-01 0.138 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 7.279016e-01 0.138 0 0
Thromboxane signalling through TP receptor R-HSA-428930 7.279016e-01 0.138 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 7.279016e-01 0.138 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.279016e-01 0.138 0 0
Mitochondrial RNA degradation R-HSA-9836573 7.279016e-01 0.138 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 7.279016e-01 0.138 0 0
Interleukin-6 family signaling R-HSA-6783589 7.279016e-01 0.138 0 0
Gastrulation R-HSA-9758941 7.301309e-01 0.137 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 7.333379e-01 0.135 0 0
TGFBR3 expression R-HSA-9839394 7.394655e-01 0.131 0 0
Laminin interactions R-HSA-3000157 7.394655e-01 0.131 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.394655e-01 0.131 0 0
Formation of the nephric duct R-HSA-9830364 7.394655e-01 0.131 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 7.394655e-01 0.131 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 7.394655e-01 0.131 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 7.411188e-01 0.130 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 7.416031e-01 0.130 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 7.416031e-01 0.130 0 0
Nucleotide biosynthesis R-HSA-8956320 7.416031e-01 0.130 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.505385e-01 0.125 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 7.505385e-01 0.125 0 0
Urea cycle R-HSA-70635 7.505385e-01 0.125 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 7.505385e-01 0.125 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 7.611416e-01 0.119 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 7.611416e-01 0.119 0 0
Insulin processing R-HSA-264876 7.611416e-01 0.119 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.611416e-01 0.119 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 7.611416e-01 0.119 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.611416e-01 0.119 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.614555e-01 0.118 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.712946e-01 0.113 0 0
IRS-mediated signalling R-HSA-112399 7.725011e-01 0.112 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 7.797042e-01 0.108 0 0
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174 7.810167e-01 0.107 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 7.810167e-01 0.107 0 0
Glucagon-type ligand receptors R-HSA-420092 7.810167e-01 0.107 0 0
Activation of the pre-replicative complex R-HSA-68962 7.903260e-01 0.102 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.903260e-01 0.102 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.903260e-01 0.102 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 7.903260e-01 0.102 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 7.903260e-01 0.102 0 0
Neurotransmitter clearance R-HSA-112311 7.903260e-01 0.102 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.903260e-01 0.102 0 0
tRNA Aminoacylation R-HSA-379724 7.935126e-01 0.100 0 0
Aspartate and asparagine metabolism R-HSA-8963693 7.992402e-01 0.097 0 0
Downstream signal transduction R-HSA-186763 7.992402e-01 0.097 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 7.999800e-01 0.097 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 8.001260e-01 0.097 0 0
Formation of paraxial mesoderm R-HSA-9793380 8.001260e-01 0.097 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 8.065509e-01 0.093 0 0
Signaling by PDGF R-HSA-186797 8.065509e-01 0.093 0 0
DAG1 glycosylations R-HSA-8931838 8.077758e-01 0.093 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 8.077758e-01 0.093 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.077758e-01 0.093 0 0
Signaling by WNT in cancer R-HSA-4791275 8.077758e-01 0.093 0 0
SLC transporter disorders R-HSA-5619102 8.120830e-01 0.090 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 8.127913e-01 0.090 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 8.159491e-01 0.088 0 0
Cardiogenesis R-HSA-9733709 8.159491e-01 0.088 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 8.159491e-01 0.088 0 0
Insulin receptor signalling cascade R-HSA-74751 8.188514e-01 0.087 0 0
IGF1R signaling cascade R-HSA-2428924 8.188514e-01 0.087 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.233108e-01 0.084 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 8.237753e-01 0.084 0 0
Glutamate and glutamine metabolism R-HSA-8964539 8.237753e-01 0.084 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.237753e-01 0.084 0 0
Miscellaneous transport and binding events R-HSA-5223345 8.237753e-01 0.084 0 0
Heme degradation R-HSA-189483 8.237753e-01 0.084 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 8.247352e-01 0.084 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 8.304467e-01 0.081 0 0
eNOS activation R-HSA-203615 8.312692e-01 0.080 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 8.312692e-01 0.080 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 8.312692e-01 0.080 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 8.384448e-01 0.077 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 8.384448e-01 0.077 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 8.384448e-01 0.077 0 0
Transcription of the HIV genome R-HSA-167172 8.413688e-01 0.075 0 0
GPVI-mediated activation cascade R-HSA-114604 8.453157e-01 0.073 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.453157e-01 0.073 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 8.453157e-01 0.073 0 0
RNA Polymerase III Transcription R-HSA-74158 8.453157e-01 0.073 0 0
COPII-mediated vesicle transport R-HSA-204005 8.516494e-01 0.070 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 8.518948e-01 0.070 0 0
Respiratory electron transport R-HSA-611105 8.549336e-01 0.068 0 0
Purine salvage R-HSA-74217 8.581945e-01 0.066 0 0
Keratinization R-HSA-6805567 8.583028e-01 0.066 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 8.642265e-01 0.063 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 8.642265e-01 0.063 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.642265e-01 0.063 0 0
PI Metabolism R-HSA-1483255 8.674100e-01 0.062 0 0
Diseases of Immune System R-HSA-5260271 8.700024e-01 0.060 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.700024e-01 0.060 0 0
Tryptophan catabolism R-HSA-71240 8.700024e-01 0.060 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 8.700024e-01 0.060 0 0
Interleukin-2 family signaling R-HSA-451927 8.700024e-01 0.060 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 8.704095e-01 0.060 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 8.755328e-01 0.058 0 0
Maturation of spike protein R-HSA-9694548 8.755328e-01 0.058 0 0
Intra-Golgi traffic R-HSA-6811438 8.808283e-01 0.055 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 8.808283e-01 0.055 0 0
Signaling by FGFR1 in disease R-HSA-5655302 8.808283e-01 0.055 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.858988e-01 0.053 0 0
G alpha (i) signalling events R-HSA-418594 8.866473e-01 0.052 0 0
Methylation R-HSA-156581 8.954027e-01 0.048 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 8.954027e-01 0.048 0 0
Amine ligand-binding receptors R-HSA-375280 8.954027e-01 0.048 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.998539e-01 0.046 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 8.998539e-01 0.046 0 0
Bacterial Infection Pathways R-HSA-9824439 9.042391e-01 0.044 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.044464e-01 0.044 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.049045e-01 0.043 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 9.121043e-01 0.040 0 0
Metal ion SLC transporters R-HSA-425410 9.121043e-01 0.040 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.121043e-01 0.040 0 0
G alpha (s) signalling events R-HSA-418555 9.143633e-01 0.039 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.158457e-01 0.038 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.173020e-01 0.037 0 0
PI3K Cascade R-HSA-109704 9.194280e-01 0.036 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.194280e-01 0.036 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.194280e-01 0.036 0 0
Complex IV assembly R-HSA-9864848 9.228581e-01 0.035 0 0
Neurexins and neuroligins R-HSA-6794361 9.261423e-01 0.033 0 0
Metabolism of nucleotides R-HSA-15869 9.268635e-01 0.033 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.281688e-01 0.032 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.292869e-01 0.032 0 0
Paracetamol ADME R-HSA-9753281 9.351807e-01 0.029 0 0
Signaling by Insulin receptor R-HSA-74752 9.354188e-01 0.029 0 0
FCGR activation R-HSA-2029481 9.376774e-01 0.028 0 0
Collagen formation R-HSA-1474290 9.398610e-01 0.027 0 0
Dectin-2 family R-HSA-5621480 9.405838e-01 0.027 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.431144e-01 0.025 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.435819e-01 0.025 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.455372e-01 0.024 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.455372e-01 0.024 0 0
Metabolism of polyamines R-HSA-351202 9.478571e-01 0.023 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.478571e-01 0.023 0 0
Aquaporin-mediated transport R-HSA-445717 9.500782e-01 0.022 0 0
Nucleotide salvage R-HSA-8956321 9.500782e-01 0.022 0 0
Complex I biogenesis R-HSA-6799198 9.542410e-01 0.020 0 0
Xenobiotics R-HSA-211981 9.561906e-01 0.019 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.615556e-01 0.017 0 0
Metabolism of steroid hormones R-HSA-196071 9.615556e-01 0.017 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.631939e-01 0.016 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.662643e-01 0.015 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.665138e-01 0.015 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.677023e-01 0.014 0 0
Metabolism of cofactors R-HSA-8978934 9.677023e-01 0.014 0 0
Metabolism of porphyrins R-HSA-189445 9.677023e-01 0.014 0 0
Purine catabolism R-HSA-74259 9.690790e-01 0.014 0 0
Aspirin ADME R-HSA-9749641 9.703971e-01 0.013 0 0
Signaling by FGFR in disease R-HSA-1226099 9.716591e-01 0.012 0 0
Visual phototransduction R-HSA-2187338 9.741104e-01 0.011 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.758028e-01 0.011 0 0
G alpha (12/13) signalling events R-HSA-416482 9.761922e-01 0.010 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.772075e-01 0.010 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.772075e-01 0.010 0 0
Peptide hormone metabolism R-HSA-2980736 9.775334e-01 0.010 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.791101e-01 0.009 0 0
Protein-protein interactions at synapses R-HSA-6794362 9.824528e-01 0.008 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.832497e-01 0.007 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 9.839181e-01 0.007 0 0
Neurotransmitter release cycle R-HSA-112310 9.864923e-01 0.006 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.904718e-01 0.004 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.904718e-01 0.004 0 0
GPCR downstream signalling R-HSA-388396 9.917480e-01 0.004 0 0
Drug ADME R-HSA-9748784 9.921345e-01 0.003 0 0
Peptide ligand-binding receptors R-HSA-375276 9.934090e-01 0.003 0 0
Diseases of metabolism R-HSA-5668914 9.935831e-01 0.003 0 0
Arachidonate metabolism R-HSA-2142753 9.948776e-01 0.002 0 0
Antimicrobial peptides R-HSA-6803157 9.952614e-01 0.002 0 0
Transport of small molecules R-HSA-382551 9.958819e-01 0.002 0 0
Signaling by GPCR R-HSA-372790 9.972022e-01 0.001 0 0
Nucleotide catabolism R-HSA-8956319 9.981076e-01 0.001 0 0
Adipogenesis R-HSA-9843745 9.983403e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.984113e-01 0.001 0 0
Diseases of glycosylation R-HSA-3781865 9.985862e-01 0.001 0 0
O-linked glycosylation R-HSA-5173105 9.987782e-01 0.001 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.989580e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.990093e-01 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.991006e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.991621e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.993381e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.996858e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.998853e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999339e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999819e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999850e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.999878e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999986e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999991e-01 0.000 0 0
Biological oxidations R-HSA-211859 9.999993e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999997e-01 0.000 0 0
Metabolism R-HSA-1430728 9.999999e-01 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways