JNK2
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Y Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Log-Odds: Y Sites / Y Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0MZ66 | S444 | Sugiyama | SHTN1 KIAA1598 | RPVNQTARPKTKPESSKGCEsAVDELKGILGtLNKSTSSRs |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | Y1062 | Sugiyama | POTEF A26C1B | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______ |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| O00115 | S70 | Sugiyama | DNASE2 DNASE2A DNL2 | QYKyLDEssGGWRDGRALINsPEGAVGRSLQPLyRSNTSQL |
| O00165 | S153 | Sugiyama | HAX1 HS1BP1 | PDSHQPRIFGGVLESDARSEsPQPAPDWGsQRPFHRFDDVW |
| O00299 | S221 | Sugiyama | CLIC1 G6 NCC27 | EAFRGVHRYLsNAyAREEFAstCPDDEEIELAyEQVAKALK |
| O00299 | T222 | Sugiyama | CLIC1 G6 NCC27 | AFRGVHRYLsNAyAREEFAstCPDDEEIELAyEQVAKALK_ |
| O00418 | S396 | iPTMNet | EEF2K | LsENSGDENMSDVTFDsLPSsPsSATPHSQKLDHLHWPVFS |
| O00499 | T323 | Sugiyama | BIN1 AMPHL | sPAAtPEIRVNHEPEPAGGAtPGAtLPKsPsQLRKGPPVPP |
| O14497 | S363 | Sugiyama | ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1 | AAAAAAASGGAQQRsHHAPMsPGssGGGGQPLARtPQPssP |
| O14545 | T323 | Sugiyama | TRAFD1 FLN29 | ELLIDHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQNFLQ |
| O14910 | S130 | Sugiyama | LIN7A MALS1 VELI1 | ELPKTDEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLK |
| O14979 | S241 | Sugiyama | HNRNPDL HNRPDL JKTBP | KRAKALKGKEPPKKVFVGGLsPDtsEEQIKEYFGAFGEIEN |
| O15230 | S422 | Sugiyama | LAMA5 KIAA0533 KIAA1907 | GVNCERCLPGFYRSPNHPLDsPHVCRRCNCESDFTDGtCED |
| O43242 | S430 | Sugiyama | PSMD3 | ISLSySRIsLADIAQKLQLDsPEDAEFIVAKAIRDGVIEAs |
| O43521 | S104 | SIGNOR|ELM | BCL2L11 BIM | RRSsLLSRsssGYFsFDTDRsPAPMSCDKSTQtPsPPCQAF |
| O43521 | S118 | SIGNOR|ELM | BCL2L11 BIM | sFDTDRsPAPMSCDKSTQtPsPPCQAFNHYLSAMASMRQAE |
| O43521 | S59 | SIGNOR|EPSD | BCL2L11 BIM | EPQGNPEGNHGGEGDSCPHGsPQGPLAPPAsPGPFATRsPL |
| O43521 | S69 | SIGNOR|EPSD | BCL2L11 BIM | GGEGDSCPHGsPQGPLAPPAsPGPFATRsPLFIFMRRSsLL |
| O43521 | S77 | SIGNOR|EPSD | BCL2L11 BIM | HGsPQGPLAPPAsPGPFATRsPLFIFMRRSsLLSRsssGYF |
| O43521 | T116 | SIGNOR|ELM | BCL2L11 BIM | YFsFDTDRsPAPMSCDKSTQtPsPPCQAFNHYLSAMASMRQ |
| O43765 | S77 | Sugiyama | SGTA SGT SGT1 | TLPEIFEAAATGKEMPQDLRsPARtPPsEEDsAEAERLKTE |
| O43765 | T81 | Sugiyama | SGTA SGT SGT1 | IFEAAATGKEMPQDLRsPARtPPsEEDsAEAERLKTEGNEQ |
| O43852 | S261 | Sugiyama | CALU | RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK |
| O43852 | T65 | Sugiyama | CALU | FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD |
| O60239 | S351 | SIGNOR|iPTMNet | SH3BP5 SAB | PSEMPDQFPAVVRPGSLDLPsPVsLsEFGMMFPVLGPRsEC |
| O60239 | S421 | iPTMNet | SH3BP5 SAB | NRGLSSSSGSGGSSKsQsstsPEGQALENRMKQLSLQCSKG |
| O60282 | S176 | SIGNOR | KIF5C KIAA0531 NKHC2 | VHEDKNRVPYVKGCTERFVSsPEEVMDVIDEGKANRHVAVT |
| O60361 | Y136 | Sugiyama | NME2P1 | SLRFKPEELVDYKSCAHDWVyE___________________ |
| O60701 | T185 | Sugiyama | UGDH | EGTAIKDLKNPDRVLIGGDEtPEGQRAVQALCAVYEHWVPR |
| O60784 | S461 | Sugiyama | TOM1 | EEFDKFLEERAKAADRLPNLssPsAEGPPGPPsGPAPRKKT |
| O60784 | S462 | Sugiyama | TOM1 | EFDKFLEERAKAADRLPNLssPsAEGPPGPPsGPAPRKKTQ |
| O75179 | S2042 | Sugiyama | ANKRD17 GTAR KIAA0697 | TAPTNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPLD |
| O75179 | S2045 | Sugiyama | ANKRD17 GTAR KIAA0697 | TNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPLDCGs |
| O75391 | S161 | Sugiyama | SPAG7 | LAQRQEEEAAQQGPVVVsPAsDyKDKYSHLIGKGAAKDAAH |
| O75533 | T207 | Sugiyama | SF3B1 SAP155 | AAAsQPPsKRKRRWDQtADQtPGAtPKKLssWDQAEtPGHt |
| O75533 | T223 | Sugiyama | SF3B1 SAP155 | tADQtPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsE |
| O75533 | T227 | Sugiyama | SF3B1 SAP155 | tPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsEtPGA |
| O75533 | T313 | Sugiyama | SF3B1 SAP155 | WDEtPKtERDtPGHGsGWAEtPRtDRGGDsIGEtPtPGAsK |
| O75533 | T316 | Sugiyama | SF3B1 SAP155 | tPKtERDtPGHGsGWAEtPRtDRGGDsIGEtPtPGAsKRKs |
| O75822 | T109 | Sugiyama | EIF3J EIF3S1 PRO0391 | KKRQEEIKKRLEEPEEPKVLtPEEQLADKLRLKKLQEEsDL |
| O94776 | S435 | Sugiyama | MTA2 MTA1L1 PID | RGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQtFL |
| O94776 | T438 | Sugiyama | MTA2 MTA1L1 PID | TEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQtFLLQt |
| O94842 | S178 | Sugiyama | TOX4 C14orf92 KIAA0737 | GGGTILPPAQSPEDRLsttPsPtssLHEDGVEDFRRQLPSQ |
| O94842 | T176 | Sugiyama | TOX4 C14orf92 KIAA0737 | SLGGGTILPPAQSPEDRLsttPsPtssLHEDGVEDFRRQLP |
| O95140 | S27 | SIGNOR|EPSD|PSP | MFN2 CPRP1 KIAA0214 | RCNsIVtVKKNKRHMAEVNAsPLKHFVTAKKKINGIFEQLG |
| O95359 | T2581 | Sugiyama | TACC2 | ssPVRMsEsPtPCsGssFEEtEALVNTAAKNQHPVPRGLAP |
| O95757 | S599 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00367 | T410 | Sugiyama | GLUD1 GLUD | KSNAPRVKAKIIAEGANGPttPEADKIFLERNIMVIPDLYL |
| P00533 | S511 | Sugiyama | EGFR ERBB ERBB1 HER1 | ISNRGENSCKATGQVCHALCsPEGCWGPEPRDCVSCRNVSR |
| P00558 | T376 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG |
| P00558 | T378 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA |
| P01106 | S77 | PSP | MYC BHLHE39 | PPAPSEDIWKKFELLPtPPLsPsRRsGLCsPSyVAVTPFsL |
| P01106 | S86 | PSP | MYC BHLHE39 | KKFELLPtPPLsPsRRsGLCsPSyVAVTPFsLRGDNDGGGG |
| P04083 | S170 | Sugiyama | ANXA1 ANX1 LPC1 | RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE |
| P04083 | S34 | Sugiyama | ANXA1 ANX1 LPC1 | IENEEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKA |
| P04083 | S37 | Sugiyama | ANXA1 ANX1 LPC1 | EEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKAIMV |
| P04150 | S226 | ELM | NR3C1 GRL | KETNEsPWRSDLLIDENCLLsPLAGEDDSFLLEGNSNEDCK |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04406 | Y314 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK |
| P04406 | Y320 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____ |
| P04637 | S20 | SIGNOR|EPSD|PSP | TP53 P53 | _MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQAM |
| P04637 | S46 | PSP | TP53 P53 | LPENNVLsPLPsQAMDDLMLsPDDIEQWFtEDPGPDEAPRM |
| P04637 | S6 | SIGNOR | TP53 P53 | _______________MEEPQsDPsVEPPLsQEtFsDLWKLL |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05023 | T226 | Sugiyama | ATP1A1 | IsANGCKVDNssLtGESEPQtRsPDFtNENPLETRNIAFFS |
| P05187 | S177 | Sugiyama | ALPP PLAP | RAKKAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADVP |
| P05198 | T279 | Sugiyama | EIF2S1 EIF2A | KEKIEEKRGVFNVQMEPKVVtDtDEtELARQMERLERENAE |
| P05386 | S101 | Sugiyama | RPLP1 RRP1 | APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______ |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S102 | Sugiyama | RPLP2 D11S2243E RPP2 | PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05412 | S63 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | JUN | ADPVGSLKPHLRAKNsDLLtsPDVGLLKLAsPELERLIIQS |
| P05412 | S73 | SIGNOR|EPSD|PSP | JUN | LRAKNsDLLtsPDVGLLKLAsPELERLIIQSSNGHItttPt |
| P06733 | S263 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GMDVAASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsF |
| P06733 | S272 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI |
| P06733 | S291 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06733 | Y280 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD |
| P06733 | Y44 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK |
| P06744 | S455 | Sugiyama | GPI | ALMRGKSTEEARKELQAAGKsPEDLERLLPHKVFEGNRPTN |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07437 | S115 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL |
| P07437 | T107 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC |
| P07437 | Y106 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAES |
| P07741 | S30 | Sugiyama | APRT | EQRIRsFPDFPTPGVVFRDIsPVLKDPASFRAAIGLLARHL |
| P07814 | S886 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | EKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPEAKVLFD |
| P07814 | Y827 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07900 | S263 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | EEKEKEEKEsEDKPEIEDVGsDEEEEKKDGDKKKKKKIKEK |
| P07900 | S391 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P07900 | T305 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IDQEELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLA |
| P07900 | T317 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08195 | S607 | Sugiyama | SLC3A2 MDU1 | ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP |
| P08238 | S383 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P08238 | T309 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08238 | Y301 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF |
| P08865 | T97 | Sugiyama | RPSA LAMBR LAMR1 | IssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQAAFR |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09104 | Y44 | Sugiyama | ENO2 | LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK |
| P09382 | S63 | Sugiyama | LGALS1 | CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG |
| P09382 | T58 | Sugiyama | LGALS1 | DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF |
| P09923 | S174 | Sugiyama | ALPI | RAKQAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMP |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG38 | Y1062 | Sugiyama | POTEI | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | Y1025 | Sugiyama | POTEJ | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P0DPH7 | S48 | Sugiyama | TUBA3C TUBA2 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P0DPH7 | T51 | Sugiyama | TUBA3C TUBA2 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P10415 | S70 | GPS6|SIGNOR | BCL2 | SSQPGHtPHPAASRDPVARtsPLQtPAAPGAAAGPALsPVP |
| P10415 | S87 | GPS6 | BCL2 | ARtsPLQtPAAPGAAAGPALsPVPPVVHLTLRQAGDDFSRR |
| P10415 | T56 | GPS6 | BCL2 | GAAPPGAAPAPGIFSSQPGHtPHPAASRDPVARtsPLQtPA |
| P10415 | T74 | GPS6 | BCL2 | GHtPHPAASRDPVARtsPLQtPAAPGAAAGPALsPVPPVVH |
| P10809 | S453 | Sugiyama | HSPD1 HSP60 | EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK |
| P10809 | T206 | Sugiyama | HSPD1 HSP60 | IsDAMKKVGRKGVITVKDGKtLNDELEIIEGMKFDRGyIsP |
| P10809 | T455 | Sugiyama | HSPD1 HSP60 | GIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLKIP |
| P11142 | T226 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK |
| P11142 | T37 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P11142 | T38 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P11142 | T45 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P11802 | T172 | EPSD|PSP | CDK4 | GTVKLADFGLARIYSYQMALtPVVVTLWYRAPEVLLQSTYA |
| P12270 | S2155 | Sugiyama | TPR | PstPtLVVPHRtDGFAEAIHsPQVAGVPRFRFGPPEDMPQT |
| P12277 | T35 | Sugiyama | CKB CKBB | PAEDEFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDD |
| P13804 | S192 | Sugiyama | ETFA | sFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPEL |
| P13804 | T191 | Sugiyama | ETFA | tsFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPE |
| P13807 | S723 | Sugiyama | GYS1 GYS | TSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN______ |
| P13807 | T721 | Sugiyama | GYS1 GYS | sSTSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN____ |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P13929 | Y44 | Sugiyama | ENO3 | LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK |
| P14314 | S442 | Sugiyama | PRKCSH G19P1 | EYVYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSA |
| P14314 | T444 | Sugiyama | PRKCSH G19P1 | VYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMK |
| P14314 | T469 | Sugiyama | PRKCSH G19P1 | WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt |
| P14618 | T195 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | yVDDGLISLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAA |
| P14625 | S552 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | KEKQDKIyFMAGsSRKEAEssPFVERLLKKGyEVIyLTEPV |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14866 | S101 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | GAAGGGGGGENyDDPHKtPAsPVVHIRGLIDGVVEADLVEA |
| P15311 | T533 | Sugiyama | EZR VIL2 | NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII |
| P15336 | S90 | EPSD|PSP | ATF2 CREB2 CREBP1 | PtPtRFLKNCEEVGLFNELAsPFENEFKKASEDDIKKMPLD |
| P15336 | T69 | SIGNOR|iPTMNet|EPSD|PSP | ATF2 CREB2 CREBP1 | HEMtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELA |
| P15336 | T71 | SIGNOR|iPTMNet|EPSD|PSP | ATF2 CREB2 CREBP1 | MtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELAsP |
| P16104 | S140 | SIGNOR | H2AX H2AFX | KtsAtVGPKAPSGGKKAtQAsQEy_________________ |
| P16333 | S89 | Sugiyama | NCK1 NCK | KNLKDTLGIGKVKRKPsVPDsAsPADDsFVDPGERLyDLNM |
| P16949 | S38 | SIGNOR | STMN1 C1orf215 LAP18 OP18 | QAFELILsPRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAE |
| P17812 | S575 | Sugiyama | CTPS1 CTPS | LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____ |
| P18669 | S152 | Sugiyama | PGAM1 PGAMA CDABP0006 | FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV |
| P18669 | S31 | Sugiyama | PGAM1 PGAMA CDABP0006 | HGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALRDAGyE |
| P18669 | T146 | Sugiyama | PGAM1 PGAMA CDABP0006 | MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF |
| P19338 | S619 | Sugiyama | NCL | RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK |
| P19419 | S383 | iPTMNet|EPSD | ELK1 | tPVLLtPSSLPPSIHFWSTLsPIAPRsPAKLSFQFPSSGSA |
| P19419 | S389 | SIGNOR|iPTMNet|EPSD | ELK1 | PSSLPPSIHFWSTLsPIAPRsPAKLSFQFPSSGSAQVHIPS |
| P19793 | S260 | SIGNOR|EPSD|PSP | RXRA NR2B1 | LAVEPKTETyVEANMGLNPssPNDPVtNICQAADKQLFTLV |
| P20042 | S67 | Sugiyama | EIF2S2 EIF2B | EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK |
| P21333 | S1084 | Sugiyama | FLNA FLN FLN1 | PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV |
| P21333 | S2319 | Sugiyama | FLNA FLN FLN1 | VQEPGDyEVsVKFNEEHIPDsPFVVPVAsPsGDARRLtVss |
| P21333 | S2327 | Sugiyama | FLNA FLN FLN1 | VsVKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKV |
| P21333 | S2329 | Sugiyama | FLNA FLN FLN1 | VKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKVNQ |
| P22392 | Y151 | Sugiyama | NME2 NM23B | SLWFKPEELVDyKSCAHDWVyE___________________ |
| P23246 | T687 | Sugiyama | SFPQ PSF | FGQGGAGPVGGQGPRGMGPGtPAGyGRGREEYEGPNKKPRF |
| P23528 | Y140 | Sugiyama | CFL1 CFL | SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs |
| P24752 | T220 | Sugiyama | ACAT1 ACAT MAT | TAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVtV |
| P25054 | S1100 | Sugiyama | APC DP2.5 | ESTDDKHLKFQPHFGQQECVsPYRSRGANGSETNRVGSNHG |
| P26639 | T246 | Sugiyama | TARS1 TARS | LLAMFKYNKFKCRILNEKVNtPtttVyRCGPLIDLCRGPHV |
| P29401 | S105 | Sugiyama | TKT | VWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGsL |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | S443 | Sugiyama | TKT | EDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAAN |
| P29401 | T287 | Sugiyama | TKT | AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP |
| P29692 | S133 | Sugiyama | EEF1D EF1D | NVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPAEDDE |
| P29692 | S162 | Sugiyama | EEF1D EF1D | AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY |
| P29692 | S70 | Sugiyama | EEF1D EF1D | IARARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVE |
| P29692 | T147 | Sugiyama | EEF1D EF1D | PQtQHVsPMRQVEPPAKKPAtPAEDDEDDDIDLFGsDNEEE |
| P29966 | S26 | Sugiyama | MARCKS MACS PRKCSL | SKTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAs |
| P29966 | S27 | Sugiyama | MARCKS MACS PRKCSL | KTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAsP |
| P29966 | S46 | EPSD|PSP | MARCKS MACS PRKCSL | ssPsKANGQENGHVKVNGDAsPAAAEsGAKEELQANGsAPA |
| P30041 | T177 | Sugiyama | PRDX6 AOP2 KIAA0106 | FDEILRVVISLQLTAEKRVAtPVDWKDGDsVMVLPtIPEEE |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30050 | S26 | Sugiyama | RPL12 | DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI |
| P30086 | T42 | Sugiyama | PEBP1 PBP PEBP | QHPLHVTYAGAAVDELGKVLtPtQVKNRPtsIsWDGLDsGK |
| P30086 | T69 | Sugiyama | PEBP1 PBP PEBP | RPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWHHFLV |
| P30101 | S443 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | LsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLN |
| P30101 | Y115 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA |
| P30307 | S168 | SIGNOR|EPSD|PSP | CDC25C | SANKENDNGNLVDSEMKYLGsPITTVPKLDKNPNLGEDQAE |
| P31150 | S316 | Sugiyama | GDI1 GDIL OPHN2 RABGDIA XAP4 | QVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSDIYVCM |
| P31645 | T616 | EPSD|PSP | SLC6A4 HTT SERT | RLIITPGtFKERIIKsItPEtPTEIPCGDIRLNAV______ |
| P31943 | S104 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | EVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK |
| P31947 | S186 | SIGNOR | SFN HME1 | NPIRLGLALNFSVFHYEIANsPEEAISLAKTtFDEAMADLH |
| P32322 | S294 | Sugiyama | PYCR1 | QEQVSPAAIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLA |
| P32322 | S301 | Sugiyama | PYCR1 | AIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLAPAGKD__ |
| P33176 | S175 | Sugiyama | KIF5B KNS KNS1 | VHEDKNRVPYVKGCTERFVCsPDEVMDtIDEGKSNRHVAVT |
| P33316 | Y167 | Sugiyama | DUT | PPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDVGAG |
| P34931 | T39 | Sugiyama | HSPA1L | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P34931 | T40 | Sugiyama | HSPA1L | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P34931 | T47 | Sugiyama | HSPA1L | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P35222 | S191 | SIGNOR | CTNNB1 CTNNB OK/SW-cl.35 PRO2286 | AAVMVHQLsKKEAsRHAIMRsPQMVSAIVRTMQNTNDVETA |
| P35222 | S37 | SIGNOR | CTNNB1 CTNNB OK/SW-cl.35 PRO2286 | DRKAAVsHWQQQsyLDsGIHsGATtTAPsLsGKGNPEEEDV |
| P35222 | S605 | SIGNOR | CTNNB1 CTNNB OK/SW-cl.35 PRO2286 | HNRIVIRGLNTIPLFVQLLYsPIENIQRVAAGVLCELAQDK |
| P35222 | T41 | SIGNOR | CTNNB1 CTNNB OK/SW-cl.35 PRO2286 | AVsHWQQQsyLDsGIHsGATtTAPsLsGKGNPEEEDVDTsQ |
| P35568 | S307 | SIGNOR | IRS1 | HHLNNPPPSQVGLTRRsRtEsItAtsPAsMVGGKPGsFRVR |
| P35568 | S312 | SIGNOR | IRS1 | PPPSQVGLTRRsRtEsItAtsPAsMVGGKPGsFRVRAssDG |
| P35568 | S315 | SIGNOR | IRS1 | SQVGLTRRsRtEsItAtsPAsMVGGKPGsFRVRAssDGEGt |
| P35568 | Y612 | SIGNOR | IRS1 | LERRGGHHRPDsstLHtDDGyMPMsPGVAPVPSGRKGsGDy |
| P35568 | Y632 | SIGNOR | IRS1 | yMPMsPGVAPVPSGRKGsGDyMPMsPKsVSAPQQIINPIRR |
| P35606 | T828 | Sugiyama | COPB2 | EEWVKETHADLWPAKQyPLVtPNEERNVMEEGKDFQPSRst |
| P35998 | T193 | Sugiyama | PSMC2 MSS1 | TYSDVGGCKEQIEKLREVVEtPLLHPERFVNLGIEPPKGVL |
| P36578 | S295 | Sugiyama | RPL4 RPL1 | sNyNLPMHKMINtDLsRILKsPEIQRALRAPRKKIHRRVLK |
| P36956 | S117 | PSP | SREBF1 BHLHD1 SREBP1 | LSPPQPAPTPLKMYPSMPAFsPGPGIKEESVPLSILQTPTP |
| P37802 | S145 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN |
| P38646 | S549 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | IVHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYA |
| P38936 | S130 | EPSD|PSP | CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 | HVDLsLSCTLVPRsGEQAEGsPGGPGDSQGRKRRQtsMTDF |
| P38936 | S98 | EPSD|PSP | CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 | LPtGPRRGRDELGGGRRPGtsPALLQGTAEEDHVDLsLSCT |
| P38936 | T57 | EPSD|PSP | CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 | LMAGCIQEARERWNFDFVtEtPLEGDFAWERVRGLGLPKLy |
| P39019 | Y48 | Sugiyama | RPS19 | LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG |
| P40763 | S727 | SIGNOR|PSP | STAT3 APRF | KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS |
| P41970 | S357 | ELM|iPTMNet | ELK3 NET SAP2 | NGLLLTPSPLLSSIHFWSSLsPVAPLsPARLQGPSTLFQFP |
| P45984 | T183 | Sugiyama | MAPK9 JNK2 PRKM9 SAPK1A | CTLKILDFGLARTACTNFMMtPyVVtRYYRAPEVILGMGYK |
| P45984 | T188 | Sugiyama | MAPK9 JNK2 PRKM9 SAPK1A | LDFGLARTACTNFMMtPyVVtRYYRAPEVILGMGYKENVDI |
| P45984 | Y185 | Sugiyama | MAPK9 JNK2 PRKM9 SAPK1A | LKILDFGLARTACTNFMMtPyVVtRYYRAPEVILGMGYKEN |
| P46937 | S138 | GPS6|SIGNOR|PSP | YAP1 YAP65 | LtPQHVRAHssPAsLQLGAVsPGtLtPtGVVsGPAAtPTAQ |
| P46937 | S289 | Sugiyama | YAP1 YAP65 | MNQRIsQsAPVKQPPPLAPQsPQGGVMGGsNsNQQQQMRLQ |
| P46937 | S367 | GPS6|SIGNOR | YAP1 YAP65 | ALRSQLPtLEQDGGtQNPVssPGMsQELRTMttNssDPFLN |
| P46937 | S400 | SIGNOR | YAP1 YAP65 | NssDPFLNsGtyHsRDEstDsGLsMssysVPRtPDDFLNsV |
| P46937 | T119 | GPS6|SIGNOR|PSP|Sugiyama | YAP1 YAP65 | PEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQLGAVsP |
| P46937 | T154 | GPS6|SIGNOR|PSP | YAP1 YAP65 | LGAVsPGtLtPtGVVsGPAAtPTAQHLRQssFEIPDDVPLP |
| P46937 | T412 | GPS6 | YAP1 YAP65 | HsRDEstDsGLsMssysVPRtPDDFLNsVDEMDTGDTINQS |
| P46940 | T1410 | Sugiyama | IQGAP1 KIAA0051 | RLIVDVIRFQPGETLtEILEtPAtsEQEAEHQRAMQRRAIR |
| P47756 | S207 | Sugiyama | CAPZB | MNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKIRst |
| P49023 | S303 | Sugiyama | PXN | QRADGERCWAAGWPRDGGRssPGGQDEGGFMAQGKtGsssP |
| P49327 | S831 | Sugiyama | FASN FAS | NPNALFPPVEFPAPRGtPLIsPLIKWDHSLAWDVPAAEDFP |
| P49327 | T827 | Sugiyama | FASN FAS | GIDANPNALFPPVEFPAPRGtPLIsPLIKWDHSLAWDVPAA |
| P49448 | T410 | Sugiyama | GLUD2 GLUDP1 | KSNAPRVKAKIIAEGANGPttPEADKIFLERNILVIPDLYL |
| P49768 | S319 | SIGNOR|EPSD|PSP | PSEN1 AD3 PS1 PSNL1 | AEGDPEAQRRVsKNsKyNAEstEREsQDtVAENDDGGFsEE |
| P49768 | T320 | SIGNOR|EPSD|PSP | PSEN1 AD3 PS1 PSNL1 | EGDPEAQRRVsKNsKyNAEstEREsQDtVAENDDGGFsEEW |
| P49792 | S1400 | Sugiyama | RANBP2 NUP358 | PSNKELVGPPLAEtVFtPKtsPENVQDRFALVtPKKEGHWD |
| P49792 | S2628 | Sugiyama | RANBP2 NUP358 | NytFKtPEKAKEKKKPEDsPsDDDVLIVyELtPTAEQKALA |
| P49792 | T1144 | Sugiyama | RANBP2 NUP358 | GFRRsDDMFTFHGPGKsVFGtPtLETANKNHEtDGGsAHGD |
| P49792 | T1396 | Sugiyama | RANBP2 NUP358 | QNLNPSNKELVGPPLAEtVFtPKtsPENVQDRFALVtPKKE |
| P49792 | T1761 | Sugiyama | RANBP2 NUP358 | ATKCIACQCPSKQNQtTAIstPAssEIsKAPKsGFEGMFIR |
| P49792 | T2639 | Sugiyama | RANBP2 NUP358 | EKKKPEDsPsDDDVLIVyELtPTAEQKALATKLKLPPTFFC |
| P50395 | S316 | Sugiyama | GDI2 RABGDIB | QVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSDIyVCM |
| P50454 | S141 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI |
| P50616 | S152 | SIGNOR|EPSD|PSP | TOB1 TOB TROB1 | FNPEAQVFMPISDPASsVsssPsPPFGHsAAVsPTFMPRSt |
| P50616 | S154 | SIGNOR|EPSD|PSP | TOB1 TOB TROB1 | PEAQVFMPISDPASsVsssPsPPFGHsAAVsPTFMPRStQP |
| P50616 | S164 | SIGNOR|EPSD|PSP | TOB1 TOB TROB1 | DPASsVsssPsPPFGHsAAVsPTFMPRStQPLTFTTATFAA |
| P50991 | T50 | Sugiyama | CCT4 CCTD SRB | PAQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtI |
| P52945 | S61 | EPSD|PSP | PDX1 IPF1 STF1 | QPPPPPPHPFPGALGALEQGsPPDIsPYEVPPLADDPAVAH |
| P52945 | S66 | EPSD|PSP | PDX1 IPF1 STF1 | PPHPFPGALGALEQGsPPDIsPYEVPPLADDPAVAHLHHHL |
| P52948 | S623 | Sugiyama | NUP98 ADAR2 | KNLNNsNLFsPVNRDsENLAsPsEyPENGERFsFLSKPVDE |
| P54259 | S739 | SIGNOR | ATN1 D12S755E DRPLA | PPLSATQIKQEPAEEyEtPEsPVPPARsPsPPPKVVDVPSH |
| P54652 | T229 | Sugiyama | HSPA2 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK |
| P54652 | T38 | Sugiyama | HSPA2 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P54652 | T39 | Sugiyama | HSPA2 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P54652 | T46 | Sugiyama | HSPA2 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P55036 | S115 | Sugiyama | PSMD4 MCB1 | LALKHRQGKNHKMRIIAFVGsPVEDNEKDLVKLAKRLKKEK |
| P55209 | T62 | Sugiyama | NAP1L1 NRP | MMQNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALK |
| P55795 | S104 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | EVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK |
| P55809 | S509 | Sugiyama | OXCT1 OXCT SCOT | LWEGLTVDDVQKSTGCDFAVsPKLMPMQQIAN_________ |
| P55957 | T59 | EPSD|PSP | BID | ALGHELPVLAPQWEGyDELQtDGNRssHsRLGRIEADsEsQ |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | T106 | Sugiyama | ACTB | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60709 | Y362 | Sugiyama | ACTB | GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P60866 | T6 | Sugiyama | RPS20 | _______________MAFKDtGKtPVEPEVAIHRIRITLTS |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61978 | S216 | SIGNOR | HNRNPK HNRPK | GGKPDRVVECIKIILDLIsEsPIKGRAQPyDPNFyDETyDy |
| P61978 | S284 | Sugiyama | HNRNPK HNRPK | MPPGRGGRPMPPSRRDyDDMsPRRGPPPPPPGRGGRGGsRA |
| P61978 | S353 | SIGNOR | HNRNPK HNRPK | YDGMVGFSADETWDSAIDtWsPSEWQMAYEPQGGSGYDYSY |
| P61981 | S38 | Sugiyama | YWHAG | ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS |
| P62195 | T109 | Sugiyama | PSMC5 SUG1 | VHPEGKFVVDVDKNIDINDVtPNCRVALRNDsytLHKILPN |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62263 | S137 | Sugiyama | RPS14 PRO2640 | RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______ |
| P62263 | T133 | Sugiyama | RPS14 PRO2640 | QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__ |
| P62714 | S212 | Sugiyama | PPP2CB | EGPMCDLLWSDPDDRGGWGIsPRGAGYTFGQDISETFNHAN |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62750 | Y74 | Sugiyama | RPL23A | LRRQPKYPRKSAPRRNKLDHyAIIKFPLTTEsAMKKIEDNN |
| P62942 | S9 | Sugiyama | FKBP1A FKBP1 FKBP12 | ____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG |
| P62979 | S123 | Sugiyama | RPS27A UBA80 UBCEP1 | LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK |
| P63104 | S184 | SIGNOR | YWHAZ | HPIRLGLALNFSVFYYEILNsPEKACSLAKtAFDEAIAELD |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | T106 | Sugiyama | ACTG1 ACTG | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63261 | Y362 | Sugiyama | ACTG1 ACTG | GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P67775 | S212 | Sugiyama | PPP2CA | EGPMCDLLWSDPDDRGGWGIsPRGAGYTFGQDISETFNHAN |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68363 | S48 | Sugiyama | TUBA1B | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P68363 | T51 | Sugiyama | TUBA1B | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T80 | Sugiyama | TUBA1B | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| P68363 | Y83 | Sugiyama | TUBA1B | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| P84243 | S29 | iPTMNet | H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B | RKstGGKAPRKQLATKAARKsAPsTGGVKKPHRyRPGtVAL |
| P85037 | T436 | Sugiyama | FOXK1 MNF | sAPAsPtHPGLMsPRsGGLQtPECLsREGsPIPHDPEFGsK |
| P98177 | S230 | SIGNOR | FOXO4 AFX AFX1 MLLT7 | KAPKKKPSVLPAPPEGAtPtsPVGHFAKWSGSPCSRNREEA |
| P98177 | T227 | SIGNOR | FOXO4 AFX AFX1 MLLT7 | GRSKAPKKKPSVLPAPPEGAtPtsPVGHFAKWSGSPCSRNR |
| P98177 | T451 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | FOXO4 AFX AFX1 MLLT7 | LSMIAPPPVMASAPIPKALGtPVLtPPTEAASQDRMPQDLD |
| P98177 | T455 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | FOXO4 AFX AFX1 MLLT7 | APPPVMASAPIPKALGtPVLtPPTEAASQDRMPQDLDLDMY |
| Q00610 | S886 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | IHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsRVVG |
| Q00613 | S363 | ELM | HSF1 HSTF1 | AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE |
| Q05682 | T730 | Sugiyama | CALD1 CAD CDM | RNIKsMWEKGNVFssPtAAGtPNKEtAGLKVGVSsRINEWL |
| Q06210 | S103 | Sugiyama | GFPT1 GFAT GFPT | IEFDVHLGIAHTRWATHGEPsPVNSHPQRSDKNNEFIVIHN |
| Q06481 | T736 | EPSD|PSP | APLP2 APPL2 | LRKRQYGtISHGIVEVDPMLtPEERHLNKMQNHGyENPtyK |
| Q07020 | S130 | Sugiyama | RPL18 | RSRILRAGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYR |
| Q07021 | T165 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD |
| Q07817 | S62 | SIGNOR|EPSD|PSP | BCL2L1 BCL2L BCLX | ESEMEtPsAINGNPSWHLADsPAVNGATGHSSSLDAREVIP |
| Q07817 | T115 | SIGNOR|EPSD|PSP | BCL2L1 BCL2L BCLX | DEFELRYRRAFSDLTSQLHItPGTAYQSFEQVVNELFRDGV |
| Q07817 | T47 | SIGNOR|EPSD|PSP | BCL2L1 BCL2L BCLX | FSDVEENRTEAPEGTESEMEtPsAINGNPSWHLADsPAVNG |
| Q07866 | S460 | Sugiyama | KLC1 KLC KNS2 | QKDGTsFGEyGGWyKACKVDsPtVTTtLKNLGALyRRQGKF |
| Q07960 | S51 | Sugiyama | ARHGAP1 CDC42GAP RHOGAP1 | KNWPsDEMPDFPKsDDsKsssPELVtHLKWDDPyyDIARHQ |
| Q08AD1 | S1276 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | PQVVKQKKQRPKsIHRDHIEsPKtPIKGPPVssLsLAsLNt |
| Q08AD1 | S862 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | sKsLADIKESMENPQAKWLKsPttPIDPEKQWNLAsPsEET |
| Q08AD1 | T1279 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | VKQKKQRPKsIHRDHIEsPKtPIKGPPVssLsLAsLNtGDN |
| Q08AD1 | T865 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | LADIKESMENPQAKWLKsPttPIDPEKQWNLAsPsEETLNE |
| Q08J23 | S743 | Sugiyama | NSUN2 SAKI TRM4 | AstGQPDNDVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGV |
| Q08J23 | S751 | Sugiyama | NSUN2 SAKI TRM4 | DVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGVHPPR____ |
| Q09666 | S216 | Sugiyama | AHNAK PM227 | DVEtQsGKtVIRLPsGsGAAsPtGsAVDIRAGAIsAsGPEL |
| Q09666 | S41 | Sugiyama | AHNAK PM227 | HGLTIAQRDDGVFVQEVtQNsPAARTGVVKEGDQIVGATIy |
| Q09666 | T4564 | Sugiyama | AHNAK PM227 | LEGDLKGPKVDVKGPKVGIDtPDIDIHGPEGKLKGPKFKMP |
| Q12792 | S143 | Sugiyama | TWF1 PTK9 | GTVKEDVSLHGYKKyLLsQssPAPLtAAEEELRQIKINEVQ |
| Q12931 | S568 | Sugiyama | TRAP1 HSP75 HSPC5 | ISVETDIVVDHYKEEKFEDRsPAAECLSEKETEELMAWMRN |
| Q12968 | S163 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | NFATC3 NFAT4 | RPSRDHLyLPLEPSYRESsLsPsPASSISSRSWFsDAssCE |
| Q12968 | S165 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | NFATC3 NFAT4 | SRDHLyLPLEPSYRESsLsPsPASSISSRSWFsDAssCEsL |
| Q13066 | T39 | Sugiyama | GAGE2B GAGE2; GAGE2C | PPEMIGPMRPEQFsDEVEPAtPEEGEPATQRQDPAAAQEGE |
| Q13098 | S468 | Sugiyama | GPS1 COPS1 CSN1 | RRAKAMMLRAAVLRNQIHVKsPPREGsQGELtPANsQsRMs |
| Q13098 | T479 | Sugiyama | GPS1 COPS1 CSN1 | VLRNQIHVKsPPREGsQGELtPANsQsRMstNM________ |
| Q13200 | S16 | Sugiyama | PSMD2 TRAP2 | _____MEEGGRDKAPVQPQQsPAAAPGGtDEKPsGKERRDA |
| Q13263 | S512 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | RLDLDLtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATG |
| Q13263 | T513 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | LDLDLtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATGQ |
| Q13283 | S232 | Sugiyama | G3BP1 G3BP | EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA |
| Q13283 | T241 | Sugiyama | G3BP1 G3BP | ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP |
| Q13451 | T46 | Sugiyama | FKBP5 AIG6 FKBP51 | TsKKDRGVLKIVKRVGNGEEtPMIGDKVyVHYKGKLSNGKK |
| Q13509 | S115 | Sugiyama | TUBB3 TUBB4 | SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL |
| Q13509 | T107 | Sugiyama | TUBB3 TUBB4 | PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC |
| Q13509 | Y106 | Sugiyama | TUBB3 TUBB4 | RPDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECEN |
| Q13526 | S115 | SIGNOR|PSP | PIN1 | KIKSGEEDFEsLAsQFSDCSsAKARGDLGAFsRGQMQKPFE |
| Q13541 | S86 | Sugiyama | EIF4EBP1 | PVtKtPPRDLPtIPGVtsPssDEPPMEAsQsHLRNsPEDKR |
| Q13541 | S96 | Sugiyama | EIF4EBP1 | PtIPGVtsPssDEPPMEAsQsHLRNsPEDKRAGGEEsQFEM |
| Q13573 | S224 | Sugiyama | SNW1 SKIIP SKIP | KDPMEPPRFKINKKIPRGPPsPPAPVMHsPsRKMTVKEQQE |
| Q13573 | S232 | Sugiyama | SNW1 SKIIP SKIP | FKINKKIPRGPPsPPAPVMHsPsRKMTVKEQQEWKIPPCIS |
| Q13884 | S87 | Sugiyama | SNTB1 SNT2B1 | SFCRGAGAGHPGAGGAQPPDsPAGVRTAFTDLPEQVPESIS |
| Q13885 | S115 | Sugiyama | TUBB2A TUBB2 | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q13885 | T107 | Sugiyama | TUBB2A TUBB2 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q13885 | Y106 | Sugiyama | TUBB2A TUBB2 | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESES |
| Q14103 | S190 | Sugiyama | HNRNPD AUF1 HNRPD | KRAKAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVES |
| Q14103 | T193 | Sugiyama | HNRNPD AUF1 HNRPD | KAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVESIEL |
| Q14157 | S470 | Sugiyama | UBAP2L KIAA0144 NICE4 | PPPssPLPsKstsAPQMsPGssDNQsssPQPAQQKLKQQKK |
| Q14160 | S504 | Sugiyama | SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL | MKRSIEGRRsEACPCQPDsGsPLPAEEEKRLsAESGLSEDS |
| Q14247 | S405 | Sugiyama | CTTN EMS1 | EEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVyEDAA |
| Q14247 | S418 | Sugiyama | CTTN EMS1 | KtQtPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVs |
| Q14934 | S213 | GPS6|EPSD|PSP | NFATC4 NFAT3 | AACDEVESELNEAASRFGLGsPLPsPRASPRPWtPEDPWSL |
| Q14934 | S217 | GPS6|EPSD|PSP | NFATC4 NFAT3 | EVESELNEAASRFGLGsPLPsPRASPRPWtPEDPWSLYGPS |
| Q14980 | S1757 | Sugiyama | NUMA1 NMP22 NUMA | ITSKLPRtQPDGtsVPGEPAsPIsQRLPPKVEsLEsLyFtP |
| Q15181 | S250 | Sugiyama | PPA1 IOPPP PP | LVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDALPPPC |
| Q15181 | T245 | Sugiyama | PPA1 IOPPP PP | DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA |
| Q15181 | T246 | Sugiyama | PPA1 IOPPP PP | HWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDAL |
| Q15185 | S113 | Sugiyama | PTGES3 P23 TEBP | RAKLNWLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGD |
| Q15293 | T211 | Sugiyama | RCN1 RCN | FTAFLHPEEFEHMKEIVVLEtLEDIDKNGDGFVDQDEyIAD |
| Q15293 | T71 | Sugiyama | RCN1 RCN | EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI |
| Q15293 | T76 | Sugiyama | RCN1 RCN | FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD |
| Q15293 | Y278 | Sugiyama | RCN1 RCN | LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE |
| Q15637 | S80 | Sugiyama | SF1 ZFM1 ZNF162 | DLTRKLRtGDLGIPPNPEDRsPsPEPIyNsEGKRLNTREFR |
| Q15637 | T232 | Sugiyama | SF1 ZFM1 ZNF162 | MENVKKAVEQIRNILKQGIEtPEDQNDLRKMQLRELARLNG |
| Q15642 | S304 | Sugiyama | TRIP10 CIP4 STOT STP | FEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRTKRWPFG |
| Q15642 | T302 | Sugiyama | TRIP10 CIP4 STOT STP | VEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRTKRWP |
| Q15750 | S438 | PSP | TAB1 MAP3K7IP1 | VNGAHsASTLDEAtPTLTNQsPTLTLQSTNTHTQssSSssD |
| Q15773 | S238 | Sugiyama | MLF2 | GAGGRRAEGPPRLAIQGPEDsPsRQsRRYDW__________ |
| Q16204 | S244 | Sugiyama | CCDC6 D10S170 TST1 | LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF |
| Q16630 | T157 | Sugiyama | CPSF6 CFIM68 | SKKLMDLLPKRELHGQNPVVtPCNKQFLsQFEMQSRKTTQS |
| Q16643 | T346 | Sugiyama | DBN1 D0S117E | RRMAPtPIPtRsPsDsstAstPVAEQIERALDEVTsSQPPP |
| Q27J81 | S589 | Sugiyama | INF2 C14orf151 C14orf173 | WQKLPsNVAREHNsMWAsLssPDAEAVEPDFSSIERLFSFP |
| Q4KMP7 | T150 | Sugiyama | TBC1D10B FP2461 | ADsPKtEEARPsPAPGPGtPtGtPtRtPsRtAPGALTAKPP |
| Q4V328 | S655 | Sugiyama | GRIPAP1 KIAA1167 | ILTNSKSRSGLEELVLsEMNsPSRtQtGDsssIssFsYREI |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q5JR12 | S93 | SIGNOR | PPM1J PPP2CZ | LQLsPGGLRRADDHAGRAVQsPPDTGRRLPWSTGYAEVINA |
| Q5JSH3 | S96 | Sugiyama | WDR44 RPH11 | QLEDDsLDSKGKELsDQAtAsPIVARTDLSNIPGLLAIDQV |
| Q5SW79 | T1533 | Sugiyama | CEP170 FAM68A KAB KIAA0470 | LPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAVSAAA |
| Q5T035 | T77 | Sugiyama | FAM120A2P C9orf129 | SGKNLtEQNsysNIPHEGKHtPLyERSLPINPAQSGSPNHV |
| Q5T4S7 | S178 | Sugiyama | UBR4 KIAA0462 KIAA1307 RBAF600 | AKLPQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLT |
| Q5VT52 | S965 | Sugiyama | RPRD2 KIAA0460 HSPC099 | NsLsQsttGHLSLPQKQyPDsPHPVPHRsLFsPQNtLAAPT |
| Q66K74 | S759 | Sugiyama | MAP1S BPY2IP1 C19orf5 MAP8 VCY2IP1 | LVsPCEFEHRKAVPMAPAPAsPGssNDssARsQERAGGLGA |
| Q68CZ2 | S660 | Sugiyama | TNS3 TEM6 TENS1 TPP | RVAVQRGVGsGPHPPDTQQPsPsKAFKPRFPGDQVVNGAGP |
| Q6EMK4 | S322 | Sugiyama | VASN SLITL2 UNQ314/PRO357/PRO1282 | CVCPLSWFGPWVRESHVTLAsPEETRCHFPPKNAGRLLLEL |
| Q6NT46 | T39 | Sugiyama | GAGE2A GAGE2 | PPEMIGPMRPEQFsDEVEPAtPEEGEPATQRQDPAAAQEGQ |
| Q6PEY2 | S48 | Sugiyama | TUBA3E | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q6PEY2 | T51 | Sugiyama | TUBA3E | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q6PKG0 | S521 | Sugiyama | LARP1 KIAA0731 LARP | NCPEFVPRQHYQKEtEsAPGsPRAVtPVPtKTEEVSNLKTL |
| Q6PKG0 | S774 | Sugiyama | LARP1 KIAA0731 LARP | LFGAPEPstIARsLPttVPEsPNyRNtRtPRtPRtPQLKDS |
| Q6PKG0 | T526 | Sugiyama | LARP1 KIAA0731 LARP | VPRQHYQKEtEsAPGsPRAVtPVPtKTEEVSNLKTLPKGLs |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | Y1062 | Sugiyama | POTEE A26C1A POTE2 | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q71U36 | S48 | Sugiyama | TUBA1A TUBA3 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q71U36 | T51 | Sugiyama | TUBA1A TUBA3 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T80 | Sugiyama | TUBA1A TUBA3 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q71U36 | Y83 | Sugiyama | TUBA1A TUBA3 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q7L2J0 | S216 | Sugiyama | MEPCE BCDIN3 | NLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPKDIt |
| Q7L2J0 | T213 | Sugiyama | MEPCE BCDIN3 | DPLNLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPK |
| Q7Z417 | S692 | Sugiyama | NUFIP2 KIAA1321 PIG1 | IWNLQKQDPKRIItyNEAMDsPDQ_________________ |
| Q7Z6Z7 | T2889 | Sugiyama | HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272 | EAVGDTSAAGSSEQPRAGsstPGDAPPAVAEVQGRSDGsGE |
| Q86UY5 | S353 | Sugiyama | FAM83A TSGP | NPFSGRSAGSHPGTRsVsAssGPCsPAAPHPPPPPRFQPHQ |
| Q86UY5 | S357 | Sugiyama | FAM83A TSGP | GRSAGSHPGTRsVsAssGPCsPAAPHPPPPPRFQPHQGPWG |
| Q8IW41 | T182 | GPS6|ELM|iPTMNet|EPSD|PSP | MAPKAPK5 PRAK | DAPVKLCDFGFAKIDQGDLMtPQFtPyYVAPQVLEAQRRHQ |
| Q8IZ21 | S118 | Sugiyama | PHACTR4 PRO2963 | PSDAMLKNGHTTPIGNARsssPVQVEEEPVRLAsLRKAIPE |
| Q8N1F7 | S430 | Sugiyama | NUP93 KIAA0095 | TEDYLWLKLNQVCFDDDGTssPQDRLTLsQFQKQLLEDYGE |
| Q8N684 | T203 | Sugiyama | CPSF7 | GGIPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLP |
| Q8NBJ5 | S612 | Sugiyama | COLGALT1 GLT25D1 PSEC0241 | QKMREQQALSREAKNsDVLQsPLDsAARDEL__________ |
| Q8TAQ2 | S283 | Sugiyama | SMARCC2 BAF170 | KNPVSRRKKISAKtLtDEVNsPDsDRRDKKGGNYKKRKRsP |
| Q8TC07 | S675 | Sugiyama | TBC1D15 | TSAFQSNALPTLSASGARNDsPtQIPVssDVCRLtPA____ |
| Q8WUI4 | S109 | Sugiyama | HDAC7 HDAC7A | LAEVILKKQQAALERtVHPNsPGIPYRTLEPLETEGATRSM |
| Q8WW12 | T139 | Sugiyama | PCNP | sEPEEMPPEAKMRMKNIGRDtPtsAGPNsFNKGKHGFsDNQ |
| Q8WW12 | T141 | Sugiyama | PCNP | PEEMPPEAKMRMKNIGRDtPtsAGPNsFNKGKHGFsDNQKL |
| Q8WWM7 | S111 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | PGAAAIGsARGQstGKGPPQsPVFEGVyNNSRMLHFLTAVV |
| Q8WWM7 | S594 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | EEPKGKEKEVDGLLtsEPMGsPVssKtEsVsDKEDKPPLAP |
| Q8WYK2 | T148 | GPS6|iPTMNet|EPSD|PSP | JDP2 | LILMLNRHRPTCIVRTDsVKtPEsEGNPLLEQLEKK_____ |
| Q92530 | S153 | Sugiyama | PSMF1 | RIVSGIITPIHEQWEKANVssPHREFPPAtAREVDPLRIPP |
| Q92609 | S539 | Sugiyama | TBC1D5 KIAA0210 | KsEsMPVQLNKGLSSKNIsssPsVEsLPGGREFtGsPPssA |
| Q92614 | S157 | Sugiyama | MYO18A CD245 KIAA0216 MYSPDZ TIAF1 | KRFsFsQRsRDEsAsEtstPsEHsAAPsPQVEVRTLEGQLV |
| Q92614 | S164 | Sugiyama | MYO18A CD245 KIAA0216 MYSPDZ TIAF1 | RsRDEsAsEtstPsEHsAAPsPQVEVRTLEGQLVQHPGPGI |
| Q92614 | T155 | Sugiyama | MYO18A CD245 KIAA0216 MYSPDZ TIAF1 | IVKRFsFsQRsRDEsAsEtstPsEHsAAPsPQVEVRTLEGQ |
| Q92879 | S179 | Sugiyama | CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 | AMAQTAIKAMHQAQtMEGCssPMVVKFADTQKDKEQKRMAQ |
| Q92945 | S181 | Sugiyama | KHSRP FUBP2 | GRGGEQINKIQQDSGCKVQIsPDsGGLPERsVsLtGAPEsV |
| Q96B36 | S212 | Sugiyama | AKT1S1 PRAS40 | GFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAED |
| Q96C19 | S74 | Sugiyama | EFHD2 SWS1 | ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI |
| Q96D15 | T72 | Sugiyama | RCN3 UNQ239/PRO272 | FQYDHEAFLGREVAKEFDQLtPEEsQARLGRIVDRMDRAGD |
| Q96H79 | S256 | Sugiyama | ZC3HAV1L C7orf39 | QIISTYKHMKLHKMLENtDNssPsTEHsQGLEKQGVHAAGA |
| Q96H79 | S257 | Sugiyama | ZC3HAV1L C7orf39 | IISTYKHMKLHKMLENtDNssPsTEHsQGLEKQGVHAAGAA |
| Q96HN2 | S107 | Sugiyama | AHCYL2 KIAA0828 | KRSDPHHQHQRHRDGGEALVsPDGTVTEAPRTVKKQIQFAD |
| Q96K76 | S910 | Sugiyama | USP47 | DGDNGDssKstEtsDFENIEsPLNERDsSAsVDNRELEQHI |
| Q96L14 | T242 | Sugiyama | CEP170P1 CEP170L KIAA0470L | LPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAVSAAA |
| Q96MH2 | S76 | Sugiyama | HEXIM2 L3 | EDLAGAVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPS |
| Q96N67 | S910 | Sugiyama | DOCK7 KIAA1771 | NLNRsRsLsNsNPDIsGtPtsPDDEVRsIIGSKGLDRsNsW |
| Q96N67 | T909 | Sugiyama | DOCK7 KIAA1771 | LNLNRsRsLsNsNPDIsGtPtsPDDEVRsIIGSKGLDRsNs |
| Q96S44 | T8 | Sugiyama | TP53RK C20orf64 PRPK | _____________MAAARAttPADGEEPAPEAEALAAARER |
| Q99933 | S205 | Sugiyama | BAG1 HAP | QSFQKLIFKGKSLKEMEtPLsALGIQDGCRVMLIGKKNsPQ |
| Q99933 | T202 | Sugiyama | BAG1 HAP | GVPQSFQKLIFKGKSLKEMEtPLsALGIQDGCRVMLIGKKN |
| Q9BPU6 | T509 | Sugiyama | DPYSL5 CRMP5 ULIP6 | RTPYLGDVAVVVHPGKKEMGtPLADtPtRPVTRHGGMRDLH |
| Q9BPU6 | T514 | Sugiyama | DPYSL5 CRMP5 ULIP6 | GDVAVVVHPGKKEMGtPLADtPtRPVTRHGGMRDLHEssFs |
| Q9BQ16 | T118 | Sugiyama | SPOCK3 TICN3 UNQ409/PRO771 | HKVCIAQDSQTAVCISHRRLtHRMKEAGVDHRQWRGPILST |
| Q9BQE3 | S48 | Sugiyama | TUBA1C TUBA6 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q9BQE3 | T51 | Sugiyama | TUBA1C TUBA6 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T80 | Sugiyama | TUBA1C TUBA6 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q9BQE3 | Y83 | Sugiyama | TUBA1C TUBA6 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q9BQG0 | S11 | Sugiyama | MYBBP1A P160 | __________MEsRDPAQPMsPGEAtQsGARPADRYGLLKH |
| Q9BQQ3 | S274 | EPSD|PSP | GORASP1 GOLPH5 GRASP65 | MEALLQAPGSSMEDPLPGPGsPSHSAPDPDGLPHFMETPLQ |
| Q9BV73 | S2229 | Sugiyama | CEP250 CEP2 CNAP1 | QRLQDELELTRRALEKERLHsPGAtsTAELGSRGEQGVQLG |
| Q9BVA1 | S115 | Sugiyama | TUBB2B | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q9BVA1 | T107 | Sugiyama | TUBB2B | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q9BVA1 | Y106 | Sugiyama | TUBB2B | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESES |
| Q9BX68 | T47 | Sugiyama | HINT2 | QVRGAAGVTDGNEVAKAQQAtPGGAAPtIFsRILDKsLPAD |
| Q9BY44 | S506 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | KNQRKHEAKKAAKQEARsDKsPDLAPtPAPQstPRNtVsQs |
| Q9BY44 | T512 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | EAKKAAKQEARsDKsPDLAPtPAPQstPRNtVsQsIsGDPE |
| Q9BY77 | S275 | Sugiyama | POLDIP3 KIAA1649 PDIP46 | RTLVNKEEPPKELPAAEPVLsPLEGTKMTVNNLHPRVTEED |
| Q9BYG3 | T234 | Sugiyama | NIFK MKI67IP NOPP34 | KKKVsGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELND |
| Q9BYG3 | T238 | Sugiyama | NIFK MKI67IP NOPP34 | sGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELNDDDKD |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9BYX7 | Y362 | Sugiyama | POTEKP ACTBL3 FKSG30 | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| Q9C0C2 | S1103 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ |
| Q9C0C2 | S1297 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | GQADWtPDLGLRNMAPGAVCsPGEsKELGVGQMDWGNNLGL |
| Q9C0C2 | S435 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | DAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAALPQGQG |
| Q9C0C2 | S494 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | QSFEWTFPTRPSGLGVWRLDsPPPsPItEAsEAAEAAEAGN |
| Q9C0C2 | S498 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | WTFPTRPSGLGVWRLDsPPPsPItEAsEAAEAAEAGNLAVS |
| Q9C0C2 | S672 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | TLARAETtQARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsP |
| Q9GZR2 | S15 | Sugiyama | REXO4 PMC2 XPMC2H | ______MGKAKVPASKRAPssPVAKPGPVKTLTRKKNKKKK |
| Q9H0D6 | T433 | Sugiyama | XRN2 | SFRRRQKEKRKRMKRDQPAFtPsGILtPHALGsRNsPGsQV |
| Q9H0D6 | T439 | Sugiyama | XRN2 | KEKRKRMKRDQPAFtPsGILtPHALGsRNsPGsQVAsNPRQ |
| Q9H1A4 | S313 | Sugiyama | ANAPC1 TSG24 | QNVAtsssLTAHLRsLsKGDsPVtsPFQNysSIHSQSRSTs |
| Q9H1A4 | T316 | Sugiyama | ANAPC1 TSG24 | AtsssLTAHLRsLsKGDsPVtsPFQNysSIHSQSRSTssPs |
| Q9H2U2 | S317 | Sugiyama | PPA2 HSPC124 | DSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK___ |
| Q9H488 | S264 | Sugiyama | POFUT1 FUT12 KIAA0180 | DWKNACAMLKDGTAGSHFMAsPQCVGySRSTAAPLTMTMCL |
| Q9H4A5 | S112 | Sugiyama | GOLPH3L GPP34R | EPPTMRKKRLLDRKVLLKsDsPTGDVLLDETLKHIKATEPT |
| Q9HAP6 | S115 | Sugiyama | LIN7B MALS2 VELI2 UNQ3116/PRO10200 | ELPKTDEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLK |
| Q9HAU0 | S933 | Sugiyama | PLEKHA5 KIAA1686 PEPP2 | QQACLREKKKGLNVIGAsDQsPLQsPsNLRDNPFRTTQTRR |
| Q9HAU0 | S937 | Sugiyama | PLEKHA5 KIAA1686 PEPP2 | LREKKKGLNVIGAsDQsPLQsPsNLRDNPFRTTQTRRRDDK |
| Q9HC38 | T242 | Sugiyama | GLOD4 C17orf25 CGI-150 My027 | PQKELPDLEDLMKRENQKILtPLVsLDtPGKATVQVVILAD |
| Q9HC38 | T249 | Sugiyama | GLOD4 C17orf25 CGI-150 My027 | LEDLMKRENQKILtPLVsLDtPGKATVQVVILADPDGHEIC |
| Q9HCD6 | S169 | Sugiyama | TANC2 KIAA1148 KIAA1636 | tLPPISTNATAKDCSyGAVtsPtstLESRDSGIIATLTSYS |
| Q9NQR4 | S133 | Sugiyama | NIT2 CUA002 | IHLFDIDVPGKITFQESKTLsPGDsFSTFDTPyCRVGLGIC |
| Q9NUP9 | S115 | Sugiyama | LIN7C MALS3 VELI3 | ELPKTEEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLK |
| Q9NUQ3 | S97 | Sugiyama | TXLNG CXorf15 ELRG LSR5 | KHSLEEDEGsDFItENRNLVsPAyCtQEsREEIPGGEARTD |
| Q9NYV6 | T200 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | RRN3 TIFIA | PANFDTCHRALQIIARYVPstPWFLMPILVEKFPFVRKSER |
| Q9NZB2 | T428 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | SGKNLtEQNsysNIPHEGKHtPLyERssPINPAQsGsPNHV |
| Q9NZT2 | S315 | Sugiyama | OGFR | FKPSSLPHPLEGSRKVEEEGsPGDPDHEAstQGRTCGPEHS |
| Q9NZT2 | S378 | Sugiyama | OGFR | LERsQGDEAGGHGEDRPEPLsPKEsKKRKLELSRREQPPTE |
| Q9UGP4 | S272 | PSP | LIMD1 | GGRssEKPtGLWstASSQRVsPGLPsPNLENGAPAVGPVQP |
| Q9UGP4 | S277 | PSP | LIMD1 | EKPtGLWstASSQRVsPGLPsPNLENGAPAVGPVQPRtPsV |
| Q9UGP4 | S421 | PSP | LIMD1 | CKEGPLGWSSDGsLGsVLLDsPssPRVRLPCQPLVPGPELR |
| Q9UGP4 | S424 | PSP | LIMD1 | GPLGWSSDGsLGsVLLDsPssPRVRLPCQPLVPGPELRPSA |
| Q9UGV2 | S361 | Sugiyama | NDRG3 | sPFsRsVtsNQsDGtQESCEsPDVLDRHQTMEVsC______ |
| Q9UHB6 | S490 | Sugiyama | LIMA1 EPLIN SREBP3 PP624 | ENEEILERPAQLANAREtPHsPGVEDAPIAKVGVLAAsMEA |
| Q9UIG0 | S158 | SIGNOR|EPSD|PSP | BAZ1B WBSC10 WBSCR10 WBSCR9 WSTF | HPLEKVDEEATEKKsDGACDsPssDKENssQIAQDHQKKET |
| Q9UKG1 | T399 | Sugiyama | APPL1 APPL DIP13A KIAA1428 | LSENPEETAARVNQsALEAVtPsPsFQQRHEsLRPAAGQSR |
| Q9UKS6 | S319 | Sugiyama | PACSIN3 | FEEWsLDtQRtIsRKEKGGRsPDEVtLtsIVPTRDGTAPPP |
| Q9UPQ0 | S973 | Sugiyama | LIMCH1 KIAA1102 | SEDVKPKTLPLDKsINHQIEsPsERRKKSPREHFQAGPFsP |
| Q9UPQ0 | S975 | Sugiyama | LIMCH1 KIAA1102 | DVKPKTLPLDKsINHQIEsPsERRKKSPREHFQAGPFsPCS |
| Q9UPT6 | T265 | SIGNOR | MAPK8IP3 JIP3 KIAA1066 | SSYQCPQDEMSESGQSSAAAtPSTTGTKsNtPtssVPSAAV |
| Q9UPT6 | T275 | SIGNOR | MAPK8IP3 JIP3 KIAA1066 | SESGQSSAAAtPSTTGTKsNtPtssVPSAAVtPLNESLQPL |
| Q9UPT6 | T286 | SIGNOR | MAPK8IP3 JIP3 KIAA1066 | PSTTGTKsNtPtssVPSAAVtPLNESLQPLGDYGVGSKNSK |
| Q9UQ35 | S1103 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sPsLQSKSQTsPKGGRsRsssPVtELAsRsPIRQDRGEFsA |
| Q9UQ35 | S1404 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sELsPDAVEKAGMssNQsIssPVLDAVPRtPsRERsssAss |
| Q9UQ35 | S2132 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | SRMsCFsRPsMsPtPLDRCRsPGMLEPLGssRtPMsVLQQA |
| Q9UQ35 | S2272 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | tAVNLADsRtPAAAAAMNLAsPRtAVAPsAVNLADPRtPtA |
| Q9UQ35 | S857 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sssPHPKVKsGtPPRQGsItsPQANEQsVtPQRRsCFEssP |
| Q9UQ35 | T1413 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | KAGMssNQsIssPVLDAVPRtPsRERsssAssPEMKDGLPR |
| Q9UQ35 | T866 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sGtPPRQGsItsPQANEQsVtPQRRsCFEssPDPELKsRtP |
| Q9UQF2 | S15 | ELM | MAPK8IP1 IB1 JIP1 PRKM8IP | ______MAERESGGLGGGAAsPPAASPFLGLHIAsPPNFRL |
| Q9UQF2 | S197 | ELM | MAPK8IP1 IB1 JIP1 PRKM8IP | LNNNSLGKKHSWQDRVSRSSsPLKTGEQtPPHEHICLSDEL |
| Q9UQF2 | S29 | ELM | MAPK8IP1 IB1 JIP1 PRKM8IP | LGGGAAsPPAASPFLGLHIAsPPNFRLTHDISLEEFEDEDL |
| Q9UQF2 | S341 | ELM | MAPK8IP1 IB1 JIP1 PRKM8IP | TAGRPHPSISEEEEGFDCLSsPERAEPPGGGWRGSLGEPPP |
| Q9UQF2 | S421 | ELM | MAPK8IP1 IB1 JIP1 PRKM8IP | GDYSDESDSATVYDNCASVSsPYESAIGEEYEEAPRPQPPA |
| Q9UQF2 | T103 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | MAPK8IP1 IB1 JIP1 PRKM8IP | AGSRLQAEMLQMDLIDATGDtPGAEDDEEDDDEERAARRPG |
| Q9UQF2 | T205 | GPS6|ELM | MAPK8IP1 IB1 JIP1 PRKM8IP | KHSWQDRVSRSSsPLKTGEQtPPHEHICLSDELPPQSGPAP |
| Q9UQF2 | T284 | ELM | MAPK8IP1 IB1 JIP1 PRKM8IP | RDRIHYQADVRLEATEEIYLtPVQRPPDAAEPTSAFLPPTE |
| Q9Y266 | S139 | Sugiyama | NUDC | IDQKKDAENHEAQLKNGsLDsPGKQDtEEDEEEDEKDKGKL |
| Q9Y266 | T145 | Sugiyama | NUDC | AENHEAQLKNGsLDsPGKQDtEEDEEEDEKDKGKLKPNLGN |
| Q9Y2W2 | S237 | Sugiyama | WBP11 NPWBP SIPP1 SNP70 | RKVGFALDLPPRRRDEDMLysPELAQRGHDDDVSSTSEDDG |
| Q9Y2X7 | S362 | Sugiyama | GIT1 | TLIIDILSEAKRRQQGKsLssPtDNLELsLRSQSDLDDQHD |
| Q9Y2Y9 | S119 | SIGNOR | KLF13 BTEB3 NSLP1 | PPPAPEPTSPGAEGAAAAPPsPAWsEPEPEAGLEPEREPGP |
| Q9Y2Y9 | S123 | SIGNOR | KLF13 BTEB3 NSLP1 | PEPTSPGAEGAAAAPPsPAWsEPEPEAGLEPEREPGPAGSG |
| Q9Y4E8 | S229 | Sugiyama | USP15 KIAA0529 | LVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPssLsNN |
| Q9Y4E8 | T226 | Sugiyama | USP15 KIAA0529 | GQVLVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPssL |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Chromatin organization | R-HSA-4839726 | 9.049586e-07 | 6.043 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 4.688443e-06 | 5.329 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 2.027330e-05 | 4.693 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 1.656413e-04 | 3.781 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 4.087243e-04 | 3.389 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 5.006883e-04 | 3.300 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 5.300090e-04 | 3.276 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 8.285211e-04 | 3.082 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.055711e-03 | 2.976 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 1.135909e-03 | 2.945 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 1.104431e-03 | 2.957 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.415403e-03 | 2.849 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 1.517144e-03 | 2.819 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 1.676700e-03 | 2.776 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.871434e-03 | 2.728 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 2.217599e-03 | 2.654 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 2.217599e-03 | 2.654 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 2.217599e-03 | 2.654 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.276780e-03 | 2.643 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 2.377591e-03 | 2.624 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.549308e-03 | 2.594 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 2.540721e-03 | 2.595 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 3.038491e-03 | 2.517 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.648844e-03 | 2.438 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 3.881137e-03 | 2.411 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 4.424817e-03 | 2.354 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 4.960634e-03 | 2.304 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 4.868770e-03 | 2.313 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 5.284461e-03 | 2.277 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 5.582942e-03 | 2.253 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 5.872691e-03 | 2.231 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 6.372752e-03 | 2.196 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 6.375126e-03 | 2.196 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 6.465595e-03 | 2.189 | 1 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 7.054590e-03 | 2.152 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 7.054590e-03 | 2.152 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 6.871163e-03 | 2.163 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 8.492646e-03 | 2.071 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 9.317063e-03 | 2.031 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 9.474159e-03 | 2.023 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 1.006549e-02 | 1.997 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.132575e-02 | 1.946 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.132575e-02 | 1.946 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 1.132575e-02 | 1.946 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.038118e-02 | 1.984 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 1.132575e-02 | 1.946 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.038144e-02 | 1.984 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 1.182722e-02 | 1.927 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.182722e-02 | 1.927 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.218813e-02 | 1.914 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 1.225665e-02 | 1.912 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 1.385035e-02 | 1.859 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 1.389165e-02 | 1.857 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.389165e-02 | 1.857 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 1.296001e-02 | 1.887 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.385035e-02 | 1.859 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 1.327788e-02 | 1.877 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.296001e-02 | 1.887 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.440860e-02 | 1.841 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 1.450266e-02 | 1.839 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.567289e-02 | 1.805 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.567289e-02 | 1.805 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 1.595503e-02 | 1.797 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.636963e-02 | 1.786 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.670593e-02 | 1.777 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 1.984029e-02 | 1.702 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 1.984029e-02 | 1.702 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.969703e-02 | 1.706 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 1.918357e-02 | 1.717 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.918357e-02 | 1.717 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.969703e-02 | 1.706 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.999411e-02 | 1.699 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.953554e-02 | 1.709 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 2.191465e-02 | 1.659 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.195066e-02 | 1.659 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.325670e-02 | 1.633 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 2.359392e-02 | 1.627 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.364898e-02 | 1.626 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.437197e-02 | 1.613 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 2.696552e-02 | 1.569 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 2.685600e-02 | 1.571 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 2.687307e-02 | 1.571 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 2.696552e-02 | 1.569 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 2.682983e-02 | 1.571 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 2.602040e-02 | 1.585 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 2.737126e-02 | 1.563 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 2.993878e-02 | 1.524 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 2.993878e-02 | 1.524 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 4.164213e-02 | 1.380 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 4.164213e-02 | 1.380 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 4.164213e-02 | 1.380 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.164213e-02 | 1.380 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 4.164213e-02 | 1.380 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 4.024171e-02 | 1.395 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 4.024171e-02 | 1.395 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 3.629448e-02 | 1.440 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 3.629448e-02 | 1.440 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 3.373374e-02 | 1.472 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 3.373374e-02 | 1.472 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 3.754633e-02 | 1.425 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 3.754633e-02 | 1.425 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 3.754633e-02 | 1.425 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 3.754633e-02 | 1.425 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 3.914007e-02 | 1.407 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 3.235184e-02 | 1.490 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 3.235184e-02 | 1.490 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 3.577059e-02 | 1.446 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 3.017158e-02 | 1.520 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 3.348315e-02 | 1.475 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 2.973548e-02 | 1.527 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 3.043080e-02 | 1.517 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 3.475077e-02 | 1.459 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 3.312346e-02 | 1.480 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 4.164213e-02 | 1.380 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 4.164213e-02 | 1.380 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 4.164213e-02 | 1.380 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 3.268568e-02 | 1.486 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 3.268568e-02 | 1.486 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 3.295613e-02 | 1.482 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 3.692849e-02 | 1.433 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 3.754633e-02 | 1.425 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 3.046366e-02 | 1.516 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 3.914007e-02 | 1.407 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 3.963883e-02 | 1.402 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 3.738764e-02 | 1.427 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 4.024171e-02 | 1.395 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 3.581953e-02 | 1.446 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 3.914007e-02 | 1.407 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 4.264992e-02 | 1.370 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 4.264992e-02 | 1.370 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 4.264992e-02 | 1.370 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 4.264992e-02 | 1.370 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 4.264992e-02 | 1.370 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 4.763360e-02 | 1.322 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 4.593433e-02 | 1.338 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 5.024598e-02 | 1.299 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 5.024598e-02 | 1.299 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 5.024598e-02 | 1.299 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 4.518895e-02 | 1.345 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 4.725859e-02 | 1.326 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 4.759559e-02 | 1.322 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 5.024598e-02 | 1.299 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 4.784554e-02 | 1.320 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 4.593433e-02 | 1.338 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 4.671127e-02 | 1.331 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 5.005011e-02 | 1.301 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 4.635129e-02 | 1.334 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 4.635129e-02 | 1.334 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 5.206558e-02 | 1.283 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 5.206558e-02 | 1.283 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 5.206558e-02 | 1.283 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 5.564147e-02 | 1.255 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 5.862041e-02 | 1.232 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 5.457730e-02 | 1.263 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 5.564147e-02 | 1.255 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 5.884761e-02 | 1.230 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 5.271240e-02 | 1.278 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 5.817588e-02 | 1.235 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 5.564147e-02 | 1.255 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 5.321525e-02 | 1.274 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 5.457730e-02 | 1.263 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 5.247846e-02 | 1.280 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 5.876725e-02 | 1.231 | 1 | 1 |
| Signaling by ALK in cancer | R-HSA-9700206 | 5.876725e-02 | 1.231 | 1 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 5.475626e-02 | 1.262 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 5.906601e-02 | 1.229 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 6.044624e-02 | 1.219 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 6.147980e-02 | 1.211 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 6.910289e-02 | 1.161 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 6.424458e-02 | 1.192 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.197824e-02 | 1.143 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 7.197824e-02 | 1.143 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 7.197824e-02 | 1.143 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 7.140774e-02 | 1.146 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 6.777932e-02 | 1.169 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 7.141461e-02 | 1.146 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 7.141461e-02 | 1.146 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 6.424458e-02 | 1.192 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 6.511683e-02 | 1.186 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 6.424458e-02 | 1.192 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 6.511683e-02 | 1.186 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 6.512683e-02 | 1.186 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 6.424458e-02 | 1.192 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 6.777932e-02 | 1.169 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 6.786972e-02 | 1.168 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 6.181943e-02 | 1.209 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 6.564478e-02 | 1.183 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 6.890518e-02 | 1.162 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 6.910289e-02 | 1.161 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 6.910289e-02 | 1.161 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 7.197824e-02 | 1.143 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 7.197824e-02 | 1.143 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 7.265305e-02 | 1.139 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 7.265305e-02 | 1.139 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 7.265305e-02 | 1.139 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 7.265305e-02 | 1.139 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 7.265305e-02 | 1.139 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 7.265305e-02 | 1.139 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 7.281554e-02 | 1.138 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 7.297270e-02 | 1.137 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 7.341941e-02 | 1.134 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 7.341941e-02 | 1.134 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 7.341941e-02 | 1.134 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 7.584664e-02 | 1.120 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 7.881507e-02 | 1.103 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 7.919243e-02 | 1.101 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 8.314014e-02 | 1.080 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.314014e-02 | 1.080 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 8.314014e-02 | 1.080 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 8.314014e-02 | 1.080 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 8.338406e-02 | 1.079 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 1.008530e-01 | 0.996 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 1.008530e-01 | 0.996 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.008530e-01 | 0.996 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 9.337913e-02 | 1.030 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 8.610773e-02 | 1.065 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 8.974553e-02 | 1.047 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 9.464612e-02 | 1.024 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 8.451845e-02 | 1.073 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 9.337913e-02 | 1.030 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 9.337913e-02 | 1.030 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 9.635080e-02 | 1.016 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 8.518352e-02 | 1.070 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 9.008717e-02 | 1.045 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 9.008717e-02 | 1.045 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 8.451845e-02 | 1.073 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 9.434228e-02 | 1.025 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 8.675141e-02 | 1.062 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 1.010877e-01 | 0.995 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 1.028666e-01 | 0.988 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 1.028666e-01 | 0.988 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 1.031953e-01 | 0.986 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.038690e-01 | 0.984 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 1.041073e-01 | 0.983 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 1.041073e-01 | 0.983 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 1.041073e-01 | 0.983 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.059500e-01 | 0.975 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 1.101288e-01 | 0.958 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 1.102741e-01 | 0.958 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 1.102741e-01 | 0.958 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 1.102741e-01 | 0.958 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 1.102741e-01 | 0.958 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 1.482139e-01 | 0.829 | 0 | 0 |
| Defective SLC9A9 causes autism 16 (AUTS16) | R-HSA-5619052 | 1.482139e-01 | 0.829 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.925707e-01 | 0.715 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.925707e-01 | 0.715 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 1.925707e-01 | 0.715 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.925707e-01 | 0.715 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 1.925707e-01 | 0.715 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 1.925707e-01 | 0.715 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.925707e-01 | 0.715 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.925707e-01 | 0.715 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.925707e-01 | 0.715 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.925707e-01 | 0.715 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.925707e-01 | 0.715 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 1.925707e-01 | 0.715 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.925707e-01 | 0.715 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 1.925707e-01 | 0.715 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.925707e-01 | 0.715 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.925707e-01 | 0.715 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 2.346201e-01 | 0.630 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 2.346201e-01 | 0.630 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.179694e-01 | 0.928 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 1.357421e-01 | 0.867 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 1.357421e-01 | 0.867 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 2.744821e-01 | 0.561 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 2.744821e-01 | 0.561 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 2.744821e-01 | 0.561 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 2.744821e-01 | 0.561 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 1.728084e-01 | 0.762 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.728084e-01 | 0.762 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.728084e-01 | 0.762 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.728084e-01 | 0.762 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.728084e-01 | 0.762 | 0 | 0 |
| IRS activation | R-HSA-74713 | 3.122703e-01 | 0.505 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 3.122703e-01 | 0.505 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 3.122703e-01 | 0.505 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 3.122703e-01 | 0.505 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 3.122703e-01 | 0.505 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 3.122703e-01 | 0.505 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 1.919026e-01 | 0.717 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 1.919026e-01 | 0.717 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.919026e-01 | 0.717 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 2.112527e-01 | 0.675 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 2.112527e-01 | 0.675 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 2.112527e-01 | 0.675 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 2.112527e-01 | 0.675 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 2.112527e-01 | 0.675 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 2.112527e-01 | 0.675 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 2.112527e-01 | 0.675 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 3.480925e-01 | 0.458 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 3.480925e-01 | 0.458 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 3.480925e-01 | 0.458 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 3.480925e-01 | 0.458 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 3.480925e-01 | 0.458 | 0 | 0 |
| Defective CSF2RB causes SMDP5 | R-HSA-5688849 | 3.480925e-01 | 0.458 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 3.480925e-01 | 0.458 | 0 | 0 |
| Defective CSF2RA causes SMDP4 | R-HSA-5688890 | 3.480925e-01 | 0.458 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 1.640144e-01 | 0.785 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 1.202403e-01 | 0.920 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 1.770304e-01 | 0.752 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 2.504152e-01 | 0.601 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 2.504152e-01 | 0.601 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 3.820509e-01 | 0.418 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 3.820509e-01 | 0.418 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 3.820509e-01 | 0.418 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 3.820509e-01 | 0.418 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 1.903188e-01 | 0.721 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 1.903188e-01 | 0.721 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 2.700927e-01 | 0.568 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 2.700927e-01 | 0.568 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.700927e-01 | 0.568 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 1.251116e-01 | 0.903 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 2.175928e-01 | 0.662 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 4.142423e-01 | 0.383 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 4.142423e-01 | 0.383 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 4.142423e-01 | 0.383 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 4.142423e-01 | 0.383 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 1.121569e-01 | 0.950 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.121569e-01 | 0.950 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 3.093517e-01 | 0.510 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 2.598157e-01 | 0.585 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 3.288350e-01 | 0.483 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 4.447586e-01 | 0.352 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 4.447586e-01 | 0.352 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 4.447586e-01 | 0.352 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 4.447586e-01 | 0.352 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 4.447586e-01 | 0.352 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 2.885244e-01 | 0.540 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 3.673024e-01 | 0.435 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 3.673024e-01 | 0.435 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 4.736868e-01 | 0.325 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 4.736868e-01 | 0.325 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 4.736868e-01 | 0.325 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 3.862172e-01 | 0.413 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 3.862172e-01 | 0.413 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 3.862172e-01 | 0.413 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 3.862172e-01 | 0.413 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 4.048800e-01 | 0.393 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 5.011095e-01 | 0.300 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 5.011095e-01 | 0.300 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 5.011095e-01 | 0.300 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 4.413526e-01 | 0.355 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 4.413526e-01 | 0.355 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 5.271049e-01 | 0.278 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 5.271049e-01 | 0.278 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 3.313396e-01 | 0.480 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 3.313396e-01 | 0.480 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.626755e-01 | 0.440 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 5.517473e-01 | 0.258 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 4.936464e-01 | 0.307 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 4.597116e-01 | 0.338 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 4.466230e-01 | 0.350 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 4.168118e-01 | 0.380 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 4.356947e-01 | 0.361 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 5.267405e-01 | 0.278 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 4.562802e-01 | 0.341 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 5.427295e-01 | 0.265 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 5.427295e-01 | 0.265 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 4.456717e-01 | 0.351 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 5.514360e-01 | 0.259 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 4.597682e-01 | 0.337 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 2.456033e-01 | 0.610 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 1.640144e-01 | 0.785 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 1.640144e-01 | 0.785 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 2.393566e-01 | 0.621 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 4.349030e-01 | 0.362 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.152947e-01 | 0.938 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.152947e-01 | 0.938 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 4.868023e-01 | 0.313 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 3.673024e-01 | 0.435 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 4.633886e-01 | 0.334 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 1.202403e-01 | 0.920 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 1.387771e-01 | 0.858 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 3.029719e-01 | 0.519 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 5.478009e-01 | 0.261 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.651399e-01 | 0.782 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 2.491241e-01 | 0.604 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 5.456649e-01 | 0.263 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 2.504152e-01 | 0.601 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.251116e-01 | 0.903 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 4.142423e-01 | 0.383 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 4.179880e-01 | 0.379 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 5.261520e-01 | 0.279 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 4.868023e-01 | 0.313 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 4.320255e-01 | 0.364 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 4.735561e-01 | 0.325 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 4.735561e-01 | 0.325 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 4.735561e-01 | 0.325 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 2.112527e-01 | 0.675 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 5.011095e-01 | 0.300 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 5.011095e-01 | 0.300 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 5.271049e-01 | 0.278 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.293697e-01 | 0.888 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 1.357421e-01 | 0.867 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 4.232657e-01 | 0.373 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 4.413526e-01 | 0.355 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 4.936464e-01 | 0.307 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 5.427295e-01 | 0.265 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 5.370183e-01 | 0.270 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 1.408138e-01 | 0.851 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 2.744821e-01 | 0.561 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 3.122703e-01 | 0.505 | 0 | 0 |
| Ligand-receptor interactions | R-HSA-5632681 | 3.480925e-01 | 0.458 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 2.700927e-01 | 0.568 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 3.481642e-01 | 0.458 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 4.736868e-01 | 0.325 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 4.413526e-01 | 0.355 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 4.597116e-01 | 0.338 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 5.108605e-01 | 0.292 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 1.202403e-01 | 0.920 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 1.293697e-01 | 0.888 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 1.895037e-01 | 0.722 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 2.180402e-01 | 0.661 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 4.413526e-01 | 0.355 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 4.733367e-01 | 0.325 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 1.573248e-01 | 0.803 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 2.112527e-01 | 0.675 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 5.271049e-01 | 0.278 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 1.895037e-01 | 0.722 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 2.897554e-01 | 0.538 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 3.608625e-01 | 0.443 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 2.321722e-01 | 0.634 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 3.122703e-01 | 0.505 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 3.122703e-01 | 0.505 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.530587e-01 | 0.815 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 2.799437e-01 | 0.553 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 3.464161e-01 | 0.460 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 3.634707e-01 | 0.440 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 4.936464e-01 | 0.307 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 4.936464e-01 | 0.307 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 5.000991e-01 | 0.301 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 4.315357e-01 | 0.365 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 1.293697e-01 | 0.888 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 1.914573e-01 | 0.718 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 3.036151e-01 | 0.518 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 3.036151e-01 | 0.518 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 3.779531e-01 | 0.423 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 2.596937e-01 | 0.586 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 3.608625e-01 | 0.443 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 1.728084e-01 | 0.762 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 5.103771e-01 | 0.292 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 3.608864e-01 | 0.443 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 2.112527e-01 | 0.675 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 2.592997e-01 | 0.586 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 4.700370e-01 | 0.328 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 3.174507e-01 | 0.498 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.799437e-01 | 0.553 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 1.640144e-01 | 0.785 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 1.583721e-01 | 0.800 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 1.448010e-01 | 0.839 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 4.413526e-01 | 0.355 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 3.540636e-01 | 0.451 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 2.504710e-01 | 0.601 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 2.953627e-01 | 0.530 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 3.260773e-01 | 0.487 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 2.771939e-01 | 0.557 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 1.995469e-01 | 0.700 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 2.456033e-01 | 0.610 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 2.565840e-01 | 0.591 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 4.926607e-01 | 0.307 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 4.926607e-01 | 0.307 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 4.926607e-01 | 0.307 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 4.926607e-01 | 0.307 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 3.200734e-01 | 0.495 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 4.459374e-01 | 0.351 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.160909e-01 | 0.665 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.138227e-01 | 0.944 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 3.514717e-01 | 0.454 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 3.895904e-01 | 0.409 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 5.103771e-01 | 0.292 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 5.000991e-01 | 0.301 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 4.348587e-01 | 0.362 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 1.482139e-01 | 0.829 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 1.482139e-01 | 0.829 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 1.540565e-01 | 0.812 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 1.919026e-01 | 0.717 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.919026e-01 | 0.717 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 1.389232e-01 | 0.857 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 2.700927e-01 | 0.568 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 4.447586e-01 | 0.352 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 1.147381e-01 | 0.940 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 5.011095e-01 | 0.300 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 5.011095e-01 | 0.300 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 3.608625e-01 | 0.443 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 2.466153e-01 | 0.608 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 5.517473e-01 | 0.258 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 5.517473e-01 | 0.258 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 4.597116e-01 | 0.338 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.897683e-01 | 0.538 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.897554e-01 | 0.538 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 2.504152e-01 | 0.601 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.502220e-01 | 0.823 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 4.477205e-01 | 0.349 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 2.565840e-01 | 0.591 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 1.673363e-01 | 0.776 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.492760e-01 | 0.603 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 5.089540e-01 | 0.293 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 3.093517e-01 | 0.510 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 3.673024e-01 | 0.435 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 2.613422e-01 | 0.583 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.691891e-01 | 0.772 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 2.872975e-01 | 0.542 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 4.547009e-01 | 0.342 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.852665e-01 | 0.732 | 1 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 2.744821e-01 | 0.561 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 1.919026e-01 | 0.717 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 1.640144e-01 | 0.785 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 3.673024e-01 | 0.435 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 4.736868e-01 | 0.325 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 5.011095e-01 | 0.300 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 5.011095e-01 | 0.300 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 3.514717e-01 | 0.454 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 2.613422e-01 | 0.583 | 1 | 1 |
| HDACs deacetylate histones | R-HSA-3214815 | 4.349030e-01 | 0.362 | 0 | 0 |
| S Phase | R-HSA-69242 | 3.961380e-01 | 0.402 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 4.402591e-01 | 0.356 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 5.150743e-01 | 0.288 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 5.354691e-01 | 0.271 | 0 | 0 |
| M Phase | R-HSA-68886 | 2.531964e-01 | 0.597 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.903866e-01 | 0.720 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 2.598157e-01 | 0.585 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 2.723038e-01 | 0.565 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 4.936464e-01 | 0.307 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 3.013155e-01 | 0.521 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.364602e-01 | 0.865 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 5.103771e-01 | 0.292 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 4.765577e-01 | 0.322 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 4.765577e-01 | 0.322 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 5.103771e-01 | 0.292 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 5.261077e-01 | 0.279 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 2.545120e-01 | 0.594 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 3.235413e-01 | 0.490 | 0 | 0 |
| Kinesins | R-HSA-983189 | 4.926607e-01 | 0.307 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 4.694636e-01 | 0.328 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.857811e-01 | 0.731 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.333804e-01 | 0.632 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 3.859415e-01 | 0.413 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 2.536908e-01 | 0.596 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 1.482139e-01 | 0.829 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.700927e-01 | 0.568 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 4.142423e-01 | 0.383 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.604472e-01 | 0.795 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 3.673024e-01 | 0.435 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 4.736868e-01 | 0.325 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 3.174507e-01 | 0.498 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 3.862172e-01 | 0.413 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 3.036151e-01 | 0.518 | 0 | 0 |
| Arachidonate production from DAG | R-HSA-426048 | 5.011095e-01 | 0.300 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 5.011095e-01 | 0.300 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 5.011095e-01 | 0.300 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 2.412110e-01 | 0.618 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 5.517473e-01 | 0.258 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 5.517473e-01 | 0.258 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 5.517473e-01 | 0.258 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 5.267405e-01 | 0.278 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 5.456649e-01 | 0.263 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 4.160462e-01 | 0.381 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 4.288939e-01 | 0.368 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 5.261077e-01 | 0.279 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 4.045193e-01 | 0.393 | 1 | 0 |
| Signaling by VEGF | R-HSA-194138 | 4.735561e-01 | 0.325 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 4.926607e-01 | 0.307 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.629211e-01 | 0.788 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.152947e-01 | 0.938 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 4.503880e-01 | 0.346 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 5.099737e-01 | 0.292 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 3.464161e-01 | 0.460 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 4.460113e-01 | 0.351 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 4.838300e-01 | 0.315 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 1.728084e-01 | 0.762 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 1.269104e-01 | 0.897 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 2.017302e-01 | 0.695 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 5.011095e-01 | 0.300 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 2.709433e-01 | 0.567 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 3.836135e-01 | 0.416 | 0 | 0 |
| Attachment of bacteria to epithelial cells | R-HSA-9638630 | 5.103771e-01 | 0.292 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 5.267405e-01 | 0.278 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 2.029721e-01 | 0.693 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 2.855575e-01 | 0.544 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 4.019357e-01 | 0.396 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 1.914959e-01 | 0.718 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 4.765577e-01 | 0.322 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 2.908700e-01 | 0.536 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 2.849915e-01 | 0.545 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 5.517473e-01 | 0.258 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.658647e-01 | 0.780 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 1.175815e-01 | 0.930 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 1.919026e-01 | 0.717 | 0 | 0 |
| Relaxin receptors | R-HSA-444821 | 3.480925e-01 | 0.458 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 3.480925e-01 | 0.458 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 2.307805e-01 | 0.637 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 3.820509e-01 | 0.418 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 2.897554e-01 | 0.538 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 4.142423e-01 | 0.383 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 4.142423e-01 | 0.383 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 4.142423e-01 | 0.383 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 3.093517e-01 | 0.510 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 4.447586e-01 | 0.352 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 4.447586e-01 | 0.352 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 2.336473e-01 | 0.631 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 4.736868e-01 | 0.325 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 3.174507e-01 | 0.498 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 5.011095e-01 | 0.300 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 4.232657e-01 | 0.373 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 5.271049e-01 | 0.278 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 4.765577e-01 | 0.322 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 5.517473e-01 | 0.258 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 5.039234e-01 | 0.298 | 1 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 5.261077e-01 | 0.279 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 2.211858e-01 | 0.655 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 4.848149e-01 | 0.314 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 2.700927e-01 | 0.568 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 2.539450e-01 | 0.595 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 4.936464e-01 | 0.307 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 4.967643e-01 | 0.304 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 1.756716e-01 | 0.755 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 4.498215e-01 | 0.347 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.540565e-01 | 0.812 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 5.132183e-01 | 0.290 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 1.770304e-01 | 0.752 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 2.112482e-01 | 0.675 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.318467e-01 | 0.880 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 3.939368e-01 | 0.405 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 1.179694e-01 | 0.928 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.179694e-01 | 0.928 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 3.480925e-01 | 0.458 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 4.736868e-01 | 0.325 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.192180e-01 | 0.924 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.608625e-01 | 0.443 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 4.591219e-01 | 0.338 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 5.517473e-01 | 0.258 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 5.103771e-01 | 0.292 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 4.179309e-01 | 0.379 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.605655e-01 | 0.794 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 5.388934e-01 | 0.268 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 3.036151e-01 | 0.518 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 3.752597e-01 | 0.426 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 5.150743e-01 | 0.288 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 4.004529e-01 | 0.397 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 3.036151e-01 | 0.518 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 3.155341e-01 | 0.501 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 4.736868e-01 | 0.325 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.218237e-01 | 0.914 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 1.540565e-01 | 0.812 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 4.327713e-01 | 0.364 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 2.897683e-01 | 0.538 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 3.461373e-01 | 0.461 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.387538e-01 | 0.858 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 3.862172e-01 | 0.413 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.917472e-01 | 0.535 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 2.698153e-01 | 0.569 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 1.152947e-01 | 0.938 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 2.417297e-01 | 0.617 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.916829e-01 | 0.717 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 2.682094e-01 | 0.572 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 3.122703e-01 | 0.505 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 3.480925e-01 | 0.458 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 1.834970e-01 | 0.736 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 4.179880e-01 | 0.379 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 4.099348e-01 | 0.387 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 5.427295e-01 | 0.265 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 2.154843e-01 | 0.667 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 2.596937e-01 | 0.586 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.269104e-01 | 0.897 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 4.904045e-01 | 0.309 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 3.698037e-01 | 0.432 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 2.504152e-01 | 0.601 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 4.936464e-01 | 0.307 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 4.466230e-01 | 0.350 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 3.230224e-01 | 0.491 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 1.789139e-01 | 0.747 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.048800e-01 | 0.393 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.484492e-01 | 0.828 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 3.288350e-01 | 0.483 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 2.592997e-01 | 0.586 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.700927e-01 | 0.568 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 4.736868e-01 | 0.325 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 4.413526e-01 | 0.355 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 5.132183e-01 | 0.290 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 3.274915e-01 | 0.485 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 5.443461e-01 | 0.264 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 5.267405e-01 | 0.278 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 5.427295e-01 | 0.265 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 5.011095e-01 | 0.300 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 5.103771e-01 | 0.292 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 4.591219e-01 | 0.338 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 3.274915e-01 | 0.485 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 3.170318e-01 | 0.499 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 4.936464e-01 | 0.307 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.474092e-01 | 0.831 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 4.038383e-01 | 0.394 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 3.746070e-01 | 0.426 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 5.583388e-01 | 0.253 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 5.583388e-01 | 0.253 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 5.583388e-01 | 0.253 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 5.583388e-01 | 0.253 | 1 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 5.595111e-01 | 0.252 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 5.617153e-01 | 0.250 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 5.735644e-01 | 0.241 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 5.735644e-01 | 0.241 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 5.751071e-01 | 0.240 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 5.751071e-01 | 0.240 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 5.751071e-01 | 0.240 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 5.751071e-01 | 0.240 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 5.751071e-01 | 0.240 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 5.751071e-01 | 0.240 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 5.751071e-01 | 0.240 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 5.830114e-01 | 0.234 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 5.878193e-01 | 0.231 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 5.878193e-01 | 0.231 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 5.878193e-01 | 0.231 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 5.884040e-01 | 0.230 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 5.895659e-01 | 0.229 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 5.921914e-01 | 0.228 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 5.921914e-01 | 0.228 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 5.951859e-01 | 0.225 | 1 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 5.972508e-01 | 0.224 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 5.972508e-01 | 0.224 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 5.972508e-01 | 0.224 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 5.972508e-01 | 0.224 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 5.972508e-01 | 0.224 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 5.972508e-01 | 0.224 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 5.972508e-01 | 0.224 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 5.972508e-01 | 0.224 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 5.983324e-01 | 0.223 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 5.989201e-01 | 0.223 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 5.995181e-01 | 0.222 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 5.996471e-01 | 0.222 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 5.996471e-01 | 0.222 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 5.996471e-01 | 0.222 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 6.015277e-01 | 0.221 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 6.015277e-01 | 0.221 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 6.015277e-01 | 0.221 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 6.028565e-01 | 0.220 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 6.028565e-01 | 0.220 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 6.058835e-01 | 0.218 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 6.095781e-01 | 0.215 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 6.109968e-01 | 0.214 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 6.113480e-01 | 0.214 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 6.169218e-01 | 0.210 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 6.169218e-01 | 0.210 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 6.169218e-01 | 0.210 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 6.169218e-01 | 0.210 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 6.169218e-01 | 0.210 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 6.169218e-01 | 0.210 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 6.169218e-01 | 0.210 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 6.169218e-01 | 0.210 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 6.182417e-01 | 0.209 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 6.182417e-01 | 0.209 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 6.182417e-01 | 0.209 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 6.182417e-01 | 0.209 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 6.222529e-01 | 0.206 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 6.222529e-01 | 0.206 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 6.306012e-01 | 0.200 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 6.351508e-01 | 0.197 | 1 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 6.351508e-01 | 0.197 | 1 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 6.353200e-01 | 0.197 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 6.381398e-01 | 0.195 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 6.381398e-01 | 0.195 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 6.381398e-01 | 0.195 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 6.381398e-01 | 0.195 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 6.381398e-01 | 0.195 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 6.381398e-01 | 0.195 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 6.381398e-01 | 0.195 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 6.381398e-01 | 0.195 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 6.381398e-01 | 0.195 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 6.381398e-01 | 0.195 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 6.381398e-01 | 0.195 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 6.381398e-01 | 0.195 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 6.381398e-01 | 0.195 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 6.384455e-01 | 0.195 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 6.438965e-01 | 0.191 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 6.438965e-01 | 0.191 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 6.438965e-01 | 0.191 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 6.438965e-01 | 0.191 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 6.438965e-01 | 0.191 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 6.438965e-01 | 0.191 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 6.477530e-01 | 0.189 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 6.477530e-01 | 0.189 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 6.477530e-01 | 0.189 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 6.510229e-01 | 0.186 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 6.568107e-01 | 0.183 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 6.569003e-01 | 0.183 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 6.570020e-01 | 0.182 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 6.570020e-01 | 0.182 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 6.570020e-01 | 0.182 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 6.570020e-01 | 0.182 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 6.570020e-01 | 0.182 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 6.570020e-01 | 0.182 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 6.570020e-01 | 0.182 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 6.570020e-01 | 0.182 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 6.570020e-01 | 0.182 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 6.570020e-01 | 0.182 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 6.574378e-01 | 0.182 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 6.625204e-01 | 0.179 | 1 | 0 |
| Ion homeostasis | R-HSA-5578775 | 6.650203e-01 | 0.177 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 6.650203e-01 | 0.177 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 6.650203e-01 | 0.177 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 6.653876e-01 | 0.177 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 6.693474e-01 | 0.174 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 6.693474e-01 | 0.174 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 6.693474e-01 | 0.174 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 6.693474e-01 | 0.174 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 6.693474e-01 | 0.174 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 6.744032e-01 | 0.171 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 6.747104e-01 | 0.171 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 6.748820e-01 | 0.171 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 6.748820e-01 | 0.171 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 6.748820e-01 | 0.171 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 6.748820e-01 | 0.171 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 6.748820e-01 | 0.171 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 6.748820e-01 | 0.171 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 6.748820e-01 | 0.171 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 6.748820e-01 | 0.171 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 6.751439e-01 | 0.171 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 6.798998e-01 | 0.168 | 1 | 0 |
| tRNA processing | R-HSA-72306 | 6.803049e-01 | 0.167 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 6.815108e-01 | 0.167 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.836773e-01 | 0.165 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 6.844972e-01 | 0.165 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 6.844972e-01 | 0.165 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 6.850399e-01 | 0.164 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 6.850399e-01 | 0.164 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 6.918310e-01 | 0.160 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 6.918310e-01 | 0.160 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 6.918310e-01 | 0.160 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 6.918310e-01 | 0.160 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 6.918310e-01 | 0.160 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 6.918310e-01 | 0.160 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 6.918310e-01 | 0.160 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 6.918310e-01 | 0.160 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 6.918310e-01 | 0.160 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 6.918310e-01 | 0.160 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 6.918696e-01 | 0.160 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 6.918696e-01 | 0.160 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 6.918696e-01 | 0.160 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 6.921463e-01 | 0.160 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 6.921463e-01 | 0.160 | 1 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 6.921463e-01 | 0.160 | 1 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 6.933057e-01 | 0.159 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 6.933057e-01 | 0.159 | 0 | 0 |
| Biofilm formation | R-HSA-9931953 | 6.933057e-01 | 0.159 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 6.933057e-01 | 0.159 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.947091e-01 | 0.158 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 6.947091e-01 | 0.158 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 6.947091e-01 | 0.158 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 6.947091e-01 | 0.158 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 6.977606e-01 | 0.156 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 6.977606e-01 | 0.156 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 7.002041e-01 | 0.155 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 7.008910e-01 | 0.154 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 7.034440e-01 | 0.153 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 7.047375e-01 | 0.152 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 7.047375e-01 | 0.152 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 7.078973e-01 | 0.150 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 7.078973e-01 | 0.150 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 7.078973e-01 | 0.150 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 7.078973e-01 | 0.150 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 7.078973e-01 | 0.150 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 7.078973e-01 | 0.150 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 7.078973e-01 | 0.150 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 7.078973e-01 | 0.150 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 7.078973e-01 | 0.150 | 0 | 0 |
| PKA activation | R-HSA-163615 | 7.078973e-01 | 0.150 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 7.078973e-01 | 0.150 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 7.078973e-01 | 0.150 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 7.133705e-01 | 0.147 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 7.133705e-01 | 0.147 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 7.133705e-01 | 0.147 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 7.133705e-01 | 0.147 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 7.133705e-01 | 0.147 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 7.143606e-01 | 0.146 | 1 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 7.143606e-01 | 0.146 | 1 | 0 |
| Aggrephagy | R-HSA-9646399 | 7.158121e-01 | 0.145 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 7.158121e-01 | 0.145 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 7.163830e-01 | 0.145 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 7.176081e-01 | 0.144 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 7.214640e-01 | 0.142 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 7.223655e-01 | 0.141 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 7.231270e-01 | 0.141 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 7.231270e-01 | 0.141 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 7.231270e-01 | 0.141 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 7.231270e-01 | 0.141 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 7.231270e-01 | 0.141 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 7.231270e-01 | 0.141 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 7.231270e-01 | 0.141 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 7.242279e-01 | 0.140 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 7.265354e-01 | 0.139 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 7.265354e-01 | 0.139 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 7.274076e-01 | 0.138 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 7.337723e-01 | 0.134 | 1 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 7.337723e-01 | 0.134 | 1 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 7.353536e-01 | 0.134 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 7.353536e-01 | 0.134 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 7.369142e-01 | 0.133 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 7.369142e-01 | 0.133 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 7.369142e-01 | 0.133 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 7.369142e-01 | 0.133 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 7.369142e-01 | 0.133 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 7.369142e-01 | 0.133 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 7.369142e-01 | 0.133 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 7.375635e-01 | 0.132 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 7.375635e-01 | 0.132 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 7.375635e-01 | 0.132 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 7.375635e-01 | 0.132 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 7.375635e-01 | 0.132 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 7.375635e-01 | 0.132 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 7.403060e-01 | 0.131 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 7.421064e-01 | 0.130 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 7.421064e-01 | 0.130 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 7.421064e-01 | 0.130 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 7.443806e-01 | 0.128 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 7.467913e-01 | 0.127 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 7.469550e-01 | 0.127 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 7.512481e-01 | 0.124 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 7.512481e-01 | 0.124 | 1 | 1 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 7.512481e-01 | 0.124 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 7.512481e-01 | 0.124 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 7.512481e-01 | 0.124 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 7.512481e-01 | 0.124 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 7.512481e-01 | 0.124 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 7.539915e-01 | 0.123 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 7.543338e-01 | 0.122 | 1 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 7.566650e-01 | 0.121 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 7.566650e-01 | 0.121 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 7.640599e-01 | 0.117 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 7.640599e-01 | 0.117 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 7.642199e-01 | 0.117 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 7.642199e-01 | 0.117 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 7.642199e-01 | 0.117 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 7.642199e-01 | 0.117 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 7.642199e-01 | 0.117 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 7.642199e-01 | 0.117 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 7.642199e-01 | 0.117 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 7.642199e-01 | 0.117 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 7.642199e-01 | 0.117 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 7.660513e-01 | 0.116 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 7.664485e-01 | 0.116 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 7.678482e-01 | 0.115 | 1 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.678482e-01 | 0.115 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 7.697416e-01 | 0.114 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 7.717593e-01 | 0.113 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 7.717593e-01 | 0.113 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 7.739693e-01 | 0.111 | 1 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 7.751213e-01 | 0.111 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 7.751213e-01 | 0.111 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 7.751213e-01 | 0.111 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 7.751213e-01 | 0.111 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 7.751213e-01 | 0.111 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 7.757205e-01 | 0.110 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 7.765160e-01 | 0.110 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.765160e-01 | 0.110 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 7.765160e-01 | 0.110 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 7.765160e-01 | 0.110 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 7.765160e-01 | 0.110 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 7.772683e-01 | 0.109 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 7.838823e-01 | 0.106 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 7.838823e-01 | 0.106 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 7.865411e-01 | 0.104 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 7.876387e-01 | 0.104 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 7.881716e-01 | 0.103 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 7.881716e-01 | 0.103 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 7.881716e-01 | 0.103 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 7.881716e-01 | 0.103 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 7.881716e-01 | 0.103 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 7.894246e-01 | 0.103 | 1 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 7.907317e-01 | 0.102 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 7.915910e-01 | 0.101 | 1 | 1 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 7.917309e-01 | 0.101 | 1 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 7.923420e-01 | 0.101 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 7.923420e-01 | 0.101 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 7.923420e-01 | 0.101 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 7.936296e-01 | 0.100 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 7.936296e-01 | 0.100 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 7.939078e-01 | 0.100 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.972209e-01 | 0.098 | 1 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 7.978581e-01 | 0.098 | 1 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 7.979319e-01 | 0.098 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 7.992199e-01 | 0.097 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 7.992199e-01 | 0.097 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 7.992199e-01 | 0.097 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 8.005080e-01 | 0.097 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 8.005208e-01 | 0.097 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 8.027082e-01 | 0.095 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 8.059990e-01 | 0.094 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 8.072181e-01 | 0.093 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 8.083878e-01 | 0.092 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 8.096926e-01 | 0.092 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 8.096926e-01 | 0.092 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 8.096926e-01 | 0.092 | 0 | 0 |
| Beta-oxidation of pristanoyl-CoA | R-HSA-389887 | 8.096926e-01 | 0.092 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 8.096926e-01 | 0.092 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 8.096926e-01 | 0.092 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 8.108841e-01 | 0.091 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 8.118250e-01 | 0.091 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 8.137248e-01 | 0.090 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 8.137248e-01 | 0.090 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 8.144408e-01 | 0.089 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 8.150648e-01 | 0.089 | 1 | 0 |
| PI3K Cascade | R-HSA-109704 | 8.159890e-01 | 0.088 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 8.172656e-01 | 0.088 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 8.189463e-01 | 0.087 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 8.196197e-01 | 0.086 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 8.196197e-01 | 0.086 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 8.196197e-01 | 0.086 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 8.196197e-01 | 0.086 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 8.196197e-01 | 0.086 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 8.230475e-01 | 0.085 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 8.233193e-01 | 0.084 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 8.260539e-01 | 0.083 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 8.268324e-01 | 0.083 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 8.290295e-01 | 0.081 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 8.290295e-01 | 0.081 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 8.290295e-01 | 0.081 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 8.290295e-01 | 0.081 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 8.290295e-01 | 0.081 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 8.290295e-01 | 0.081 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 8.290295e-01 | 0.081 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 8.303863e-01 | 0.081 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 8.303863e-01 | 0.081 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 8.303863e-01 | 0.081 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 8.305808e-01 | 0.081 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 8.321372e-01 | 0.080 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 8.371974e-01 | 0.077 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 8.371974e-01 | 0.077 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 8.371974e-01 | 0.077 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 8.371974e-01 | 0.077 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 8.379174e-01 | 0.077 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 8.379490e-01 | 0.077 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 8.379490e-01 | 0.077 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 8.379490e-01 | 0.077 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 8.464036e-01 | 0.072 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 8.464036e-01 | 0.072 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 8.464036e-01 | 0.072 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 8.464036e-01 | 0.072 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 8.464036e-01 | 0.072 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 8.464036e-01 | 0.072 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 8.464036e-01 | 0.072 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 8.464036e-01 | 0.072 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 8.464036e-01 | 0.072 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 8.477521e-01 | 0.072 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 8.486972e-01 | 0.071 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 8.489637e-01 | 0.071 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 8.500817e-01 | 0.071 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 8.500817e-01 | 0.071 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 8.544177e-01 | 0.068 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 8.544177e-01 | 0.068 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 8.544177e-01 | 0.068 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 8.544177e-01 | 0.068 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 8.583128e-01 | 0.066 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 8.608290e-01 | 0.065 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 8.620140e-01 | 0.064 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 8.620140e-01 | 0.064 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.620140e-01 | 0.064 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 8.620309e-01 | 0.064 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 8.625254e-01 | 0.064 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.643529e-01 | 0.063 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 8.692145e-01 | 0.061 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 8.692145e-01 | 0.061 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 8.692145e-01 | 0.061 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 8.692145e-01 | 0.061 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 8.720025e-01 | 0.059 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 8.760396e-01 | 0.057 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 8.760396e-01 | 0.057 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 8.760396e-01 | 0.057 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 8.760396e-01 | 0.057 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 8.783253e-01 | 0.056 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 8.783253e-01 | 0.056 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 8.792701e-01 | 0.056 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 8.810237e-01 | 0.055 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 8.825089e-01 | 0.054 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 8.825089e-01 | 0.054 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 8.825089e-01 | 0.054 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 8.825089e-01 | 0.054 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 8.825089e-01 | 0.054 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 8.825089e-01 | 0.054 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 8.833496e-01 | 0.054 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 8.833496e-01 | 0.054 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 8.833496e-01 | 0.054 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 8.845279e-01 | 0.053 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 8.864145e-01 | 0.052 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 8.868353e-01 | 0.052 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 8.870105e-01 | 0.052 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 8.881813e-01 | 0.051 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 8.886410e-01 | 0.051 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 8.886410e-01 | 0.051 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 8.886410e-01 | 0.051 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 8.886410e-01 | 0.051 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 8.886410e-01 | 0.051 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 8.898215e-01 | 0.051 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 8.909064e-01 | 0.050 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 8.944533e-01 | 0.048 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 8.944533e-01 | 0.048 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 8.944533e-01 | 0.048 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 8.944533e-01 | 0.048 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 8.944533e-01 | 0.048 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 8.944533e-01 | 0.048 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 8.944533e-01 | 0.048 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 8.944533e-01 | 0.048 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 8.963725e-01 | 0.048 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 8.972925e-01 | 0.047 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 8.986931e-01 | 0.046 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 8.999627e-01 | 0.046 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 8.999627e-01 | 0.046 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 8.999627e-01 | 0.046 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 8.999627e-01 | 0.046 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 8.999627e-01 | 0.046 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 9.027676e-01 | 0.044 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 9.051848e-01 | 0.043 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 9.051848e-01 | 0.043 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 9.051848e-01 | 0.043 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.051848e-01 | 0.043 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.051848e-01 | 0.043 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.094202e-01 | 0.041 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.094202e-01 | 0.041 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.094202e-01 | 0.041 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 9.096705e-01 | 0.041 | 0 | 0 |
| Depurination | R-HSA-73927 | 9.101345e-01 | 0.041 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.101345e-01 | 0.041 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.101345e-01 | 0.041 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.109203e-01 | 0.041 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.127604e-01 | 0.040 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 9.134762e-01 | 0.039 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.135910e-01 | 0.039 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.135910e-01 | 0.039 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 9.136741e-01 | 0.039 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.148262e-01 | 0.039 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.148262e-01 | 0.039 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.159883e-01 | 0.038 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.192732e-01 | 0.037 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 9.192732e-01 | 0.037 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 9.192732e-01 | 0.037 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 9.192732e-01 | 0.037 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 9.192732e-01 | 0.037 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 9.192732e-01 | 0.037 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 9.193120e-01 | 0.037 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.206405e-01 | 0.036 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.216518e-01 | 0.035 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 9.221197e-01 | 0.035 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.234883e-01 | 0.035 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.234883e-01 | 0.035 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.234883e-01 | 0.035 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.234883e-01 | 0.035 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.234883e-01 | 0.035 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 9.234883e-01 | 0.035 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 9.240097e-01 | 0.034 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 9.240097e-01 | 0.034 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 9.240097e-01 | 0.034 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.240097e-01 | 0.034 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 9.272437e-01 | 0.033 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.274835e-01 | 0.033 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.274835e-01 | 0.033 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 9.303475e-01 | 0.031 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.312703e-01 | 0.031 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.312703e-01 | 0.031 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.312703e-01 | 0.031 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.312703e-01 | 0.031 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.312703e-01 | 0.031 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.312703e-01 | 0.031 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.331710e-01 | 0.030 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 9.344820e-01 | 0.029 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.348596e-01 | 0.029 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.348596e-01 | 0.029 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.361832e-01 | 0.029 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.382617e-01 | 0.028 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.382617e-01 | 0.028 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.382617e-01 | 0.028 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.382617e-01 | 0.028 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.382617e-01 | 0.028 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 9.396554e-01 | 0.027 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 9.414863e-01 | 0.026 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 9.414863e-01 | 0.026 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 9.414863e-01 | 0.026 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 9.414863e-01 | 0.026 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.414863e-01 | 0.026 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.414863e-01 | 0.026 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.414863e-01 | 0.026 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.414863e-01 | 0.026 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.415534e-01 | 0.026 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.440747e-01 | 0.025 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.440747e-01 | 0.025 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 9.445426e-01 | 0.025 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 9.449507e-01 | 0.025 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.459610e-01 | 0.024 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 9.474395e-01 | 0.023 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.474395e-01 | 0.023 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.474395e-01 | 0.023 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.488473e-01 | 0.023 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 9.501852e-01 | 0.022 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 9.501852e-01 | 0.022 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.501852e-01 | 0.022 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.510614e-01 | 0.022 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 9.510614e-01 | 0.022 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.518539e-01 | 0.021 | 1 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 9.527876e-01 | 0.021 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 9.531616e-01 | 0.021 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 9.547772e-01 | 0.020 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.547772e-01 | 0.020 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.552543e-01 | 0.020 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 9.565347e-01 | 0.019 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.575922e-01 | 0.019 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.575922e-01 | 0.019 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 9.575922e-01 | 0.019 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.575922e-01 | 0.019 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 9.581920e-01 | 0.019 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 9.582280e-01 | 0.019 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.582280e-01 | 0.019 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 9.590321e-01 | 0.018 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 9.590321e-01 | 0.018 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 9.598081e-01 | 0.018 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 9.598081e-01 | 0.018 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 9.598081e-01 | 0.018 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 9.598081e-01 | 0.018 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.600170e-01 | 0.018 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.600170e-01 | 0.018 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.608273e-01 | 0.017 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 9.614307e-01 | 0.017 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 9.614307e-01 | 0.017 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 9.617342e-01 | 0.017 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 9.619083e-01 | 0.017 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 9.619083e-01 | 0.017 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.619083e-01 | 0.017 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 9.638989e-01 | 0.016 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 9.638989e-01 | 0.016 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.638989e-01 | 0.016 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 9.644577e-01 | 0.016 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 9.657711e-01 | 0.015 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.657856e-01 | 0.015 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 9.657856e-01 | 0.015 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.657856e-01 | 0.015 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.659406e-01 | 0.015 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.672814e-01 | 0.014 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 9.675738e-01 | 0.014 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.687275e-01 | 0.014 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 9.690302e-01 | 0.014 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 9.697086e-01 | 0.013 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 9.697086e-01 | 0.013 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 9.701119e-01 | 0.013 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 9.714372e-01 | 0.013 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 9.720596e-01 | 0.012 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.723975e-01 | 0.012 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.723975e-01 | 0.012 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.727057e-01 | 0.012 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.737716e-01 | 0.012 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.738405e-01 | 0.012 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.738405e-01 | 0.012 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 9.739197e-01 | 0.011 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.752081e-01 | 0.011 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.752936e-01 | 0.011 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 9.761932e-01 | 0.010 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 9.765043e-01 | 0.010 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 9.772569e-01 | 0.010 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 9.772569e-01 | 0.010 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.777329e-01 | 0.010 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.782745e-01 | 0.010 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 9.788972e-01 | 0.009 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.801791e-01 | 0.009 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.810466e-01 | 0.008 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 9.812622e-01 | 0.008 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.819215e-01 | 0.008 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.820379e-01 | 0.008 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.820379e-01 | 0.008 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 9.827360e-01 | 0.008 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 9.842594e-01 | 0.007 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 9.845488e-01 | 0.007 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 9.847116e-01 | 0.007 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 9.847791e-01 | 0.007 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 9.849773e-01 | 0.007 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.855114e-01 | 0.006 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.855114e-01 | 0.006 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.862693e-01 | 0.006 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.868952e-01 | 0.006 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.869877e-01 | 0.006 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 9.875185e-01 | 0.005 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 9.880865e-01 | 0.005 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 9.892821e-01 | 0.005 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.900541e-01 | 0.004 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.900541e-01 | 0.004 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.905747e-01 | 0.004 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.914137e-01 | 0.004 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.916825e-01 | 0.004 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.923985e-01 | 0.003 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.927965e-01 | 0.003 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.928872e-01 | 0.003 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.929578e-01 | 0.003 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.937228e-01 | 0.003 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.948931e-01 | 0.002 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.950566e-01 | 0.002 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.950566e-01 | 0.002 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.961622e-01 | 0.002 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.966718e-01 | 0.001 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.967859e-01 | 0.001 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 9.967859e-01 | 0.001 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.971139e-01 | 0.001 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.971656e-01 | 0.001 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 9.976646e-01 | 0.001 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 9.978509e-01 | 0.001 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.978554e-01 | 0.001 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.979254e-01 | 0.001 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 9.980459e-01 | 0.001 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.986421e-01 | 0.001 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.987929e-01 | 0.001 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.988197e-01 | 0.001 | 1 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.994458e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 9.994741e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.994798e-01 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.994855e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.997089e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.997837e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.998337e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.998344e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.998424e-01 | 0.000 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 9.998706e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.998925e-01 | 0.000 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.998981e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999072e-01 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.999091e-01 | 0.000 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 9.999137e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999160e-01 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 9.999160e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999312e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.999673e-01 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.999673e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999691e-01 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 9.999742e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999794e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999838e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999866e-01 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.999867e-01 | 0.000 | 1 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999889e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.999944e-01 | 0.000 | 1 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999951e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999973e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999980e-01 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 9.999982e-01 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.999994e-01 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 9.999995e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.999995e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.999998e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.999999e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 1.000000e+00 | 0.000 | 1 | 1 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 5.088818e-11 | 10.293 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 4.238431e-09 | 8.373 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 5.971238e-09 | 8.224 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 7.327361e-09 | 8.135 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.234187e-08 | 7.909 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 1.510131e-08 | 7.821 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 5.899142e-08 | 7.229 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.171276e-07 | 6.931 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 1.490105e-07 | 6.827 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.504803e-07 | 6.823 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 1.739274e-07 | 6.760 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 1.953969e-07 | 6.709 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 2.819864e-07 | 6.550 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 4.859621e-07 | 6.313 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 4.920155e-07 | 6.308 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 7.812229e-07 | 6.107 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 7.783183e-07 | 6.109 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 8.457158e-07 | 6.073 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 2.281575e-06 | 5.642 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 2.452695e-06 | 5.610 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 2.635826e-06 | 5.579 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.848002e-06 | 5.545 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 3.207322e-06 | 5.494 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 3.280111e-06 | 5.484 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 3.973762e-06 | 5.401 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 4.609306e-06 | 5.336 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 7.214060e-06 | 5.142 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 9.537771e-06 | 5.021 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 1.082939e-05 | 4.965 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 1.059771e-05 | 4.975 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.369451e-05 | 4.863 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.422727e-05 | 4.847 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.885029e-05 | 4.725 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.885029e-05 | 4.725 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.957110e-05 | 4.708 | 1 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 2.248057e-05 | 4.648 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.180309e-05 | 4.661 | 0 | 0 |
| Kinesins | R-HSA-983189 | 2.341216e-05 | 4.631 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 2.729985e-05 | 4.564 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 3.218088e-05 | 4.492 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 3.218088e-05 | 4.492 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 3.294545e-05 | 4.482 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 3.407675e-05 | 4.468 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 4.150438e-05 | 4.382 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 4.241111e-05 | 4.373 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 4.508431e-05 | 4.346 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 5.279150e-05 | 4.277 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 5.391474e-05 | 4.268 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 5.309788e-05 | 4.275 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 5.468207e-05 | 4.262 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 5.559274e-05 | 4.255 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 5.743083e-05 | 4.241 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 6.740899e-05 | 4.171 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 6.916070e-05 | 4.160 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 8.141710e-05 | 4.089 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 8.239598e-05 | 4.084 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 9.010469e-05 | 4.045 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 9.010469e-05 | 4.045 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 9.467133e-05 | 4.024 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 1.038883e-04 | 3.983 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.053597e-04 | 3.977 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.060420e-04 | 3.975 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 1.063148e-04 | 3.973 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.156670e-04 | 3.937 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.427249e-04 | 3.846 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 1.638151e-04 | 3.786 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 1.638151e-04 | 3.786 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 1.945438e-04 | 3.711 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 2.004294e-04 | 3.698 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 2.004294e-04 | 3.698 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.058056e-04 | 3.687 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.058056e-04 | 3.687 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 2.099686e-04 | 3.678 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 2.259785e-04 | 3.646 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.230151e-04 | 3.652 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 2.419483e-04 | 3.616 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 2.446366e-04 | 3.611 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 2.603786e-04 | 3.584 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 2.688741e-04 | 3.570 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 2.800452e-04 | 3.553 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 3.300856e-04 | 3.481 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 3.546989e-04 | 3.450 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 3.694191e-04 | 3.432 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 3.893813e-04 | 3.410 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 4.027470e-04 | 3.395 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 3.879896e-04 | 3.411 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 4.398287e-04 | 3.357 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 4.534785e-04 | 3.343 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 5.137210e-04 | 3.289 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 5.299962e-04 | 3.276 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 5.675601e-04 | 3.246 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 5.675601e-04 | 3.246 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 6.566332e-04 | 3.183 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 6.119739e-04 | 3.213 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 7.245613e-04 | 3.140 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 7.245613e-04 | 3.140 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 7.245613e-04 | 3.140 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 7.245613e-04 | 3.140 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 7.245613e-04 | 3.140 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 8.144026e-04 | 3.089 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 8.250118e-04 | 3.084 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 7.629509e-04 | 3.118 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 8.713696e-04 | 3.060 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 8.884957e-04 | 3.051 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 9.500880e-04 | 3.022 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 9.500880e-04 | 3.022 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 9.564309e-04 | 3.019 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 1.167021e-03 | 2.933 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.322266e-03 | 2.879 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.322266e-03 | 2.879 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 1.322266e-03 | 2.879 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 1.239991e-03 | 2.907 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 1.229590e-03 | 2.910 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 1.241778e-03 | 2.906 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.322943e-03 | 2.878 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 1.612354e-03 | 2.793 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 1.612354e-03 | 2.793 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 1.690375e-03 | 2.772 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 1.690375e-03 | 2.772 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 1.769461e-03 | 2.752 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 1.735970e-03 | 2.760 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 1.892071e-03 | 2.723 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.908945e-03 | 2.719 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 2.123739e-03 | 2.673 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.241009e-03 | 2.650 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 2.315272e-03 | 2.635 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 2.334931e-03 | 2.632 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 2.401109e-03 | 2.620 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 2.428217e-03 | 2.615 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 2.542010e-03 | 2.595 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 2.588845e-03 | 2.587 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 2.588845e-03 | 2.587 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 3.046628e-03 | 2.516 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 2.858579e-03 | 2.544 | 1 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.067580e-03 | 2.513 | 1 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 3.308241e-03 | 2.480 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 3.344132e-03 | 2.476 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 3.370529e-03 | 2.472 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 3.444127e-03 | 2.463 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 3.462591e-03 | 2.461 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 3.508813e-03 | 2.455 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 3.537851e-03 | 2.451 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 3.692131e-03 | 2.433 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 4.233014e-03 | 2.373 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 4.233014e-03 | 2.373 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 4.593883e-03 | 2.338 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 4.695202e-03 | 2.328 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 4.695202e-03 | 2.328 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 4.709791e-03 | 2.327 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 5.167575e-03 | 2.287 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 5.515032e-03 | 2.258 | 1 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 5.482294e-03 | 2.261 | 0 | 0 |
| Protein folding | R-HSA-391251 | 5.924417e-03 | 2.227 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 6.000641e-03 | 2.222 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 6.109940e-03 | 2.214 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 6.501483e-03 | 2.187 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 6.965968e-03 | 2.157 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 6.965968e-03 | 2.157 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 7.227747e-03 | 2.141 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 7.241003e-03 | 2.140 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 7.940857e-03 | 2.100 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 7.940857e-03 | 2.100 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 8.118045e-03 | 2.091 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 8.668122e-03 | 2.062 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 8.768139e-03 | 2.057 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 9.091882e-03 | 2.041 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 9.443139e-03 | 2.025 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 9.628822e-03 | 2.016 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 9.628822e-03 | 2.016 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.066477e-02 | 1.972 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 1.124537e-02 | 1.949 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 9.990649e-03 | 2.000 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.112049e-02 | 1.954 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.109782e-02 | 1.955 | 1 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.056046e-02 | 1.976 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.133067e-02 | 1.946 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 1.133067e-02 | 1.946 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 1.216578e-02 | 1.915 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.222269e-02 | 1.913 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.222269e-02 | 1.913 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.222269e-02 | 1.913 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.222269e-02 | 1.913 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.222269e-02 | 1.913 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.222269e-02 | 1.913 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.274515e-02 | 1.895 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 1.313999e-02 | 1.881 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.313999e-02 | 1.881 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 1.384811e-02 | 1.859 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 1.394030e-02 | 1.856 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 1.403231e-02 | 1.853 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 1.403231e-02 | 1.853 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 1.436071e-02 | 1.843 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 1.436071e-02 | 1.843 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.491816e-02 | 1.826 | 1 | 1 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.557073e-02 | 1.808 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.846644e-02 | 1.734 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 1.846644e-02 | 1.734 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.789127e-02 | 1.747 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 1.611204e-02 | 1.793 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 1.734982e-02 | 1.761 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.601618e-02 | 1.795 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 1.724075e-02 | 1.763 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 1.879765e-02 | 1.726 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 1.944185e-02 | 1.711 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.969782e-02 | 1.706 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.969782e-02 | 1.706 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 1.974999e-02 | 1.704 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.998038e-02 | 1.699 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 1.998038e-02 | 1.699 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 2.015193e-02 | 1.696 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 2.015193e-02 | 1.696 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 2.050052e-02 | 1.688 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 2.098316e-02 | 1.678 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 2.098316e-02 | 1.678 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 2.138383e-02 | 1.670 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.306510e-02 | 1.637 | 1 | 1 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.306510e-02 | 1.637 | 1 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 2.378985e-02 | 1.624 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 2.378985e-02 | 1.624 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 2.504822e-02 | 1.601 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 2.605466e-02 | 1.584 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 2.631909e-02 | 1.580 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 2.636964e-02 | 1.579 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 3.053141e-02 | 1.515 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 3.053141e-02 | 1.515 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 2.677311e-02 | 1.572 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 2.844081e-02 | 1.546 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 2.844081e-02 | 1.546 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 2.844081e-02 | 1.546 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 2.844081e-02 | 1.546 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 3.109300e-02 | 1.507 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 2.858941e-02 | 1.544 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 2.724957e-02 | 1.565 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 2.689250e-02 | 1.570 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 3.166534e-02 | 1.499 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 2.935334e-02 | 1.532 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 2.844081e-02 | 1.546 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 2.944516e-02 | 1.531 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 3.175845e-02 | 1.498 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 3.217100e-02 | 1.493 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 3.391670e-02 | 1.470 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 3.524415e-02 | 1.453 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 3.622822e-02 | 1.441 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 3.691675e-02 | 1.433 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 3.691675e-02 | 1.433 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 3.702122e-02 | 1.432 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 3.716649e-02 | 1.430 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 3.716765e-02 | 1.430 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 3.810092e-02 | 1.419 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.840729e-02 | 1.416 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 3.921985e-02 | 1.406 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 3.957937e-02 | 1.403 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 3.957937e-02 | 1.403 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 4.040088e-02 | 1.394 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 4.040088e-02 | 1.394 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 4.078894e-02 | 1.389 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 4.078894e-02 | 1.389 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 4.243354e-02 | 1.372 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 4.390026e-02 | 1.358 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 4.390026e-02 | 1.358 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 4.393081e-02 | 1.357 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 4.518480e-02 | 1.345 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 4.570750e-02 | 1.340 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.663515e-02 | 1.331 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 4.701955e-02 | 1.328 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 4.878431e-02 | 1.312 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.012903e-02 | 1.300 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 5.116907e-02 | 1.291 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 5.116907e-02 | 1.291 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 5.144447e-02 | 1.289 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 6.503713e-02 | 1.187 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 6.420613e-02 | 1.192 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 6.420613e-02 | 1.192 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 5.409165e-02 | 1.267 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 6.387692e-02 | 1.195 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 5.861807e-02 | 1.232 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 5.664317e-02 | 1.247 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 6.487279e-02 | 1.188 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 5.963771e-02 | 1.224 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 5.764230e-02 | 1.239 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 5.208189e-02 | 1.283 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 6.420613e-02 | 1.192 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 5.854756e-02 | 1.232 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 6.440784e-02 | 1.191 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 5.552968e-02 | 1.255 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 6.503713e-02 | 1.187 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 5.409165e-02 | 1.267 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 6.387692e-02 | 1.195 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 6.027715e-02 | 1.220 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 6.420613e-02 | 1.192 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 5.871196e-02 | 1.231 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 6.420613e-02 | 1.192 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 6.527656e-02 | 1.185 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 6.530981e-02 | 1.185 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 6.562202e-02 | 1.183 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 6.677813e-02 | 1.175 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 6.775253e-02 | 1.169 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 6.817209e-02 | 1.166 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 6.907102e-02 | 1.161 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 6.907102e-02 | 1.161 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 6.907102e-02 | 1.161 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 7.024005e-02 | 1.153 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 7.024005e-02 | 1.153 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 7.100350e-02 | 1.149 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 7.250841e-02 | 1.140 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 7.450994e-02 | 1.128 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 7.452234e-02 | 1.128 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 7.551592e-02 | 1.122 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 7.650512e-02 | 1.116 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 7.664845e-02 | 1.115 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 7.720497e-02 | 1.112 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 7.747165e-02 | 1.111 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 7.769480e-02 | 1.110 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 7.814818e-02 | 1.107 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 7.860665e-02 | 1.105 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 7.860665e-02 | 1.105 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 7.860665e-02 | 1.105 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 7.860665e-02 | 1.105 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 7.860665e-02 | 1.105 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 7.927684e-02 | 1.101 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 7.927684e-02 | 1.101 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 7.939702e-02 | 1.100 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 8.103128e-02 | 1.091 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 8.244956e-02 | 1.084 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 8.264329e-02 | 1.083 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 8.264329e-02 | 1.083 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 8.454696e-02 | 1.073 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 8.505872e-02 | 1.070 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 8.802395e-02 | 1.055 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 8.883208e-02 | 1.051 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 8.883208e-02 | 1.051 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 8.883208e-02 | 1.051 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 8.968298e-02 | 1.047 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 9.053174e-02 | 1.043 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 1.147315e-01 | 0.940 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 1.147315e-01 | 0.940 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.147315e-01 | 0.940 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 9.427367e-02 | 1.026 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 9.828478e-02 | 1.008 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 9.828478e-02 | 1.008 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 9.828478e-02 | 1.008 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 1.056886e-01 | 0.976 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.173182e-01 | 0.931 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 1.103890e-01 | 0.957 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 9.828339e-02 | 1.008 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.251028e-01 | 0.903 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 9.427367e-02 | 1.026 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 1.147315e-01 | 0.940 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 9.828478e-02 | 1.008 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 1.009809e-01 | 0.996 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 1.081324e-01 | 0.966 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 1.153187e-01 | 0.938 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 1.066947e-01 | 0.972 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.075829e-01 | 0.968 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 1.168433e-01 | 0.932 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.056886e-01 | 0.976 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 9.828339e-02 | 1.008 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.075829e-01 | 0.968 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.242949e-01 | 0.906 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.247537e-01 | 0.904 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 9.427367e-02 | 1.026 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 1.251028e-01 | 0.903 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.008416e-01 | 0.996 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 1.113323e-01 | 0.953 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 1.113323e-01 | 0.953 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 9.427367e-02 | 1.026 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.062185e-01 | 0.974 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 1.274769e-01 | 0.895 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 1.274769e-01 | 0.895 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 1.285301e-01 | 0.891 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 1.289771e-01 | 0.889 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.289771e-01 | 0.889 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 1.297706e-01 | 0.887 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 1.328136e-01 | 0.877 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.360272e-01 | 0.866 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.369959e-01 | 0.863 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 1.369959e-01 | 0.863 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.385843e-01 | 0.858 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.385896e-01 | 0.858 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.385896e-01 | 0.858 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.385896e-01 | 0.858 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 1.395502e-01 | 0.855 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 1.395502e-01 | 0.855 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.407250e-01 | 0.852 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.407250e-01 | 0.852 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 1.407250e-01 | 0.852 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.422527e-01 | 0.847 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 1.422527e-01 | 0.847 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 1.422527e-01 | 0.847 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 1.432693e-01 | 0.844 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 1.442881e-01 | 0.841 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 1.457513e-01 | 0.836 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.477868e-01 | 0.830 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 1.477868e-01 | 0.830 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.477868e-01 | 0.830 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 1.490075e-01 | 0.827 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 1.490075e-01 | 0.827 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 1.490075e-01 | 0.827 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 1.490279e-01 | 0.827 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 1.510904e-01 | 0.821 | 0 | 0 |
| Activation and oligomerization of BAK protein | R-HSA-111452 | 1.522732e-01 | 0.817 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 1.522732e-01 | 0.817 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.522732e-01 | 0.817 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 1.532470e-01 | 0.815 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.534019e-01 | 0.814 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.534019e-01 | 0.814 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 1.540282e-01 | 0.812 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 1.546256e-01 | 0.811 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.550617e-01 | 0.809 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 1.588727e-01 | 0.799 | 1 | 0 |
| tRNA processing | R-HSA-72306 | 1.602264e-01 | 0.795 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 1.603472e-01 | 0.795 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.194863e-01 | 0.659 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.194863e-01 | 0.659 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 2.194863e-01 | 0.659 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 2.194863e-01 | 0.659 | 0 | 0 |
| Defective MMADHC causes MMAHCD | R-HSA-3359473 | 2.194863e-01 | 0.659 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 2.813740e-01 | 0.551 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 2.813740e-01 | 0.551 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 2.813740e-01 | 0.551 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 2.813740e-01 | 0.551 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 2.813740e-01 | 0.551 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 2.813740e-01 | 0.551 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 2.813740e-01 | 0.551 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 2.813740e-01 | 0.551 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 2.813740e-01 | 0.551 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 2.813740e-01 | 0.551 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 2.813740e-01 | 0.551 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 2.813740e-01 | 0.551 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 2.813740e-01 | 0.551 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 2.813740e-01 | 0.551 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 2.813740e-01 | 0.551 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 2.813740e-01 | 0.551 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 2.813740e-01 | 0.551 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 2.813740e-01 | 0.551 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 2.813740e-01 | 0.551 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 2.813740e-01 | 0.551 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 2.005389e-01 | 0.698 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 2.005389e-01 | 0.698 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 2.005389e-01 | 0.698 | 0 | 0 |
| Defective MMACHC causes MAHCC | R-HSA-3359474 | 3.383580e-01 | 0.471 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 3.383580e-01 | 0.471 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.383580e-01 | 0.471 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.383580e-01 | 0.471 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 2.306275e-01 | 0.637 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 2.306275e-01 | 0.637 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 2.306275e-01 | 0.637 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 2.306275e-01 | 0.637 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.609730e-01 | 0.583 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 2.609730e-01 | 0.583 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 2.609730e-01 | 0.583 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 3.908265e-01 | 0.408 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 3.908265e-01 | 0.408 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 3.908265e-01 | 0.408 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 3.908265e-01 | 0.408 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 3.908265e-01 | 0.408 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 3.908265e-01 | 0.408 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 2.086669e-01 | 0.681 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 2.086669e-01 | 0.681 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.086669e-01 | 0.681 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 2.086669e-01 | 0.681 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.086669e-01 | 0.681 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.702778e-01 | 0.769 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 2.300711e-01 | 0.638 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 2.300711e-01 | 0.638 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 2.300711e-01 | 0.638 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 2.518537e-01 | 0.599 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 3.215510e-01 | 0.493 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 4.391371e-01 | 0.357 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 4.391371e-01 | 0.357 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.391371e-01 | 0.357 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.391371e-01 | 0.357 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.800888e-01 | 0.745 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 1.800888e-01 | 0.745 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 3.514244e-01 | 0.454 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 3.514244e-01 | 0.454 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 2.961647e-01 | 0.528 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.635367e-01 | 0.786 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 3.185128e-01 | 0.497 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 3.185128e-01 | 0.497 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 3.808287e-01 | 0.419 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 3.808287e-01 | 0.419 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 3.808287e-01 | 0.419 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 4.836191e-01 | 0.315 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 4.836191e-01 | 0.315 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 4.836191e-01 | 0.315 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 4.836191e-01 | 0.315 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 4.836191e-01 | 0.315 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 4.836191e-01 | 0.315 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 4.836191e-01 | 0.315 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 4.836191e-01 | 0.315 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 4.836191e-01 | 0.315 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 4.836191e-01 | 0.315 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 3.098361e-01 | 0.509 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 3.098361e-01 | 0.509 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 4.096507e-01 | 0.388 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 4.096507e-01 | 0.388 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 2.842014e-01 | 0.546 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 1.685541e-01 | 0.773 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 3.631899e-01 | 0.440 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 3.282849e-01 | 0.484 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 3.467929e-01 | 0.460 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 3.467929e-01 | 0.460 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 3.853758e-01 | 0.414 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 3.853758e-01 | 0.414 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 3.853758e-01 | 0.414 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 3.853758e-01 | 0.414 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 4.377979e-01 | 0.359 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 4.377979e-01 | 0.359 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 4.377979e-01 | 0.359 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 4.377979e-01 | 0.359 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 4.073750e-01 | 0.390 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 4.073750e-01 | 0.390 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.480672e-01 | 0.458 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 4.651961e-01 | 0.332 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 4.651961e-01 | 0.332 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 4.651961e-01 | 0.332 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 4.651961e-01 | 0.332 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 4.291313e-01 | 0.367 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 4.291313e-01 | 0.367 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 3.965171e-01 | 0.402 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 4.505943e-01 | 0.346 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 4.341843e-01 | 0.362 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 4.166740e-01 | 0.380 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 4.628511e-01 | 0.335 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 4.628511e-01 | 0.335 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 4.382163e-01 | 0.358 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 3.631899e-01 | 0.440 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 3.631899e-01 | 0.440 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 1.769110e-01 | 0.752 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 2.739160e-01 | 0.562 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 2.739160e-01 | 0.562 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 3.480672e-01 | 0.458 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 1.800888e-01 | 0.745 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 4.022425e-01 | 0.396 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.674144e-01 | 0.776 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 3.408794e-01 | 0.467 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 3.739802e-01 | 0.427 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 3.739802e-01 | 0.427 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 3.739802e-01 | 0.427 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 3.480672e-01 | 0.458 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 2.961647e-01 | 0.528 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 2.508579e-01 | 0.601 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 3.419096e-01 | 0.466 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 3.408794e-01 | 0.467 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 3.467929e-01 | 0.460 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 4.377979e-01 | 0.359 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 4.446067e-01 | 0.352 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 4.291313e-01 | 0.367 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.961647e-01 | 0.528 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 2.609730e-01 | 0.583 | 1 | 1 |
| Regulation of CDH11 function | R-HSA-9762292 | 2.913458e-01 | 0.536 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 2.913458e-01 | 0.536 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 2.913458e-01 | 0.536 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 2.300711e-01 | 0.638 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 3.215510e-01 | 0.493 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 3.514244e-01 | 0.454 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 3.319628e-01 | 0.479 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 4.073750e-01 | 0.390 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.943191e-01 | 0.711 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 2.300711e-01 | 0.638 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 2.300711e-01 | 0.638 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 4.761440e-01 | 0.322 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 2.518625e-01 | 0.599 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 3.908265e-01 | 0.408 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 4.391371e-01 | 0.357 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 1.940386e-01 | 0.712 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 3.808287e-01 | 0.419 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 2.733027e-01 | 0.563 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.642132e-01 | 0.439 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 4.717191e-01 | 0.326 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 3.808287e-01 | 0.419 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 3.853758e-01 | 0.414 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 4.391371e-01 | 0.357 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 4.391371e-01 | 0.357 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 1.800888e-01 | 0.745 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.739160e-01 | 0.562 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 3.408794e-01 | 0.467 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 3.631899e-01 | 0.440 | 1 | 1 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.829368e-01 | 0.548 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 4.576034e-01 | 0.340 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 2.518537e-01 | 0.599 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 1.627192e-01 | 0.789 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 2.961647e-01 | 0.528 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 2.685693e-01 | 0.571 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 4.096507e-01 | 0.388 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 4.651961e-01 | 0.332 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 4.377979e-01 | 0.359 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 3.191213e-01 | 0.496 | 0 | 0 |
| S Phase | R-HSA-69242 | 3.016775e-01 | 0.520 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 3.514244e-01 | 0.454 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 3.408794e-01 | 0.467 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 4.126209e-01 | 0.384 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.898101e-01 | 0.722 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 2.609730e-01 | 0.583 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 3.808287e-01 | 0.419 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 2.373092e-01 | 0.625 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 2.518537e-01 | 0.599 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 2.375851e-01 | 0.624 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.100897e-01 | 0.678 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 4.371889e-01 | 0.359 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 4.651961e-01 | 0.332 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 1.665330e-01 | 0.778 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 2.194863e-01 | 0.659 | 0 | 0 |
| Inhibition of Host mRNA Processing and RNA Silencing | R-HSA-168315 | 2.194863e-01 | 0.659 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 2.194863e-01 | 0.659 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 2.813740e-01 | 0.551 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 3.383580e-01 | 0.471 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.383580e-01 | 0.471 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 3.908265e-01 | 0.408 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 3.908265e-01 | 0.408 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 2.086669e-01 | 0.681 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.913458e-01 | 0.536 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.518537e-01 | 0.599 | 0 | 0 |
| Regulation of gene expression in early pancreatic precursor cells | R-HSA-210747 | 3.215510e-01 | 0.493 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 4.391371e-01 | 0.357 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 4.391371e-01 | 0.357 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 2.375851e-01 | 0.624 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 2.375851e-01 | 0.624 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 2.379320e-01 | 0.624 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 1.741945e-01 | 0.759 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 4.096507e-01 | 0.388 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 3.853758e-01 | 0.414 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 3.653159e-01 | 0.437 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 4.651961e-01 | 0.332 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 4.291313e-01 | 0.367 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 3.191592e-01 | 0.496 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 4.427148e-01 | 0.354 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 3.803724e-01 | 0.420 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 2.229928e-01 | 0.652 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 4.022425e-01 | 0.396 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.853250e-01 | 0.732 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 2.209277e-01 | 0.656 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 3.762341e-01 | 0.425 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 4.689323e-01 | 0.329 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 4.096507e-01 | 0.388 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 3.428728e-01 | 0.465 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 2.171581e-01 | 0.663 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.651961e-01 | 0.332 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 4.761440e-01 | 0.322 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 4.205695e-01 | 0.376 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 2.518537e-01 | 0.599 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 2.047271e-01 | 0.689 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 2.486566e-01 | 0.604 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 2.999990e-01 | 0.523 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 4.377979e-01 | 0.359 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 3.062161e-01 | 0.514 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 3.550956e-01 | 0.450 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 2.153506e-01 | 0.667 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 3.453609e-01 | 0.462 | 1 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 4.621011e-01 | 0.335 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 2.005389e-01 | 0.698 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 3.908265e-01 | 0.408 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 2.913458e-01 | 0.536 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 2.030999e-01 | 0.692 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.808287e-01 | 0.419 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 3.808287e-01 | 0.419 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 3.808287e-01 | 0.419 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 3.808287e-01 | 0.419 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 3.991342e-01 | 0.399 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 4.286588e-01 | 0.368 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 2.804941e-01 | 0.552 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 3.282849e-01 | 0.484 | 1 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 4.645363e-01 | 0.333 | 1 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 2.014982e-01 | 0.696 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 3.186231e-01 | 0.497 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 1.702778e-01 | 0.769 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 2.091031e-01 | 0.680 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 2.479979e-01 | 0.606 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 2.702463e-01 | 0.568 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 2.913458e-01 | 0.536 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 4.391371e-01 | 0.357 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 2.229928e-01 | 0.652 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 2.229928e-01 | 0.652 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 4.096507e-01 | 0.388 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 3.653159e-01 | 0.437 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 4.775922e-01 | 0.321 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 3.663410e-01 | 0.436 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.829368e-01 | 0.548 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.185128e-01 | 0.497 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.352314e-01 | 0.629 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 4.778090e-01 | 0.321 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 4.717191e-01 | 0.326 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 4.205695e-01 | 0.376 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 4.749839e-01 | 0.323 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 3.215510e-01 | 0.493 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 4.567785e-01 | 0.340 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 2.005389e-01 | 0.698 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 2.005389e-01 | 0.698 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 3.383580e-01 | 0.471 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 2.609730e-01 | 0.583 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 2.609730e-01 | 0.583 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 1.864538e-01 | 0.729 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 3.215510e-01 | 0.493 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 4.096507e-01 | 0.388 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 2.844380e-01 | 0.546 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.840853e-01 | 0.735 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 4.693612e-01 | 0.328 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.651961e-01 | 0.332 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 3.097181e-01 | 0.509 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 4.836191e-01 | 0.315 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 4.836191e-01 | 0.315 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 3.972436e-01 | 0.401 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 3.184840e-01 | 0.497 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 4.286588e-01 | 0.368 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 3.808287e-01 | 0.419 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 4.096507e-01 | 0.388 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 4.291313e-01 | 0.367 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 3.042318e-01 | 0.517 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 3.215510e-01 | 0.493 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 4.289958e-01 | 0.368 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.864538e-01 | 0.729 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 4.391371e-01 | 0.357 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 2.733027e-01 | 0.563 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.947227e-01 | 0.531 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 4.651961e-01 | 0.332 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 3.808287e-01 | 0.419 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.644992e-01 | 0.784 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 4.604422e-01 | 0.337 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 4.717191e-01 | 0.326 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 3.467929e-01 | 0.460 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 4.291313e-01 | 0.367 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 4.607079e-01 | 0.337 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 4.889294e-01 | 0.311 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 4.911314e-01 | 0.309 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.917871e-01 | 0.308 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 4.917871e-01 | 0.308 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 4.924664e-01 | 0.308 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 4.924664e-01 | 0.308 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 4.924664e-01 | 0.308 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 4.924664e-01 | 0.308 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 4.968058e-01 | 0.304 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 5.020087e-01 | 0.299 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 5.034339e-01 | 0.298 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 5.070680e-01 | 0.295 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 5.095352e-01 | 0.293 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 5.128016e-01 | 0.290 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 5.161970e-01 | 0.287 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 5.175267e-01 | 0.286 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 5.175267e-01 | 0.286 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 5.175267e-01 | 0.286 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 5.208424e-01 | 0.283 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 5.245757e-01 | 0.280 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.245757e-01 | 0.280 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 5.245757e-01 | 0.280 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 5.245757e-01 | 0.280 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 5.245757e-01 | 0.280 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 5.245757e-01 | 0.280 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 5.245757e-01 | 0.280 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 5.245757e-01 | 0.280 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 5.245757e-01 | 0.280 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 5.266043e-01 | 0.279 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 5.288406e-01 | 0.277 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 5.288469e-01 | 0.277 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 5.313421e-01 | 0.275 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 5.402565e-01 | 0.267 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 5.423826e-01 | 0.266 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 5.423826e-01 | 0.266 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 5.423826e-01 | 0.266 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 5.423826e-01 | 0.266 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 5.423826e-01 | 0.266 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 5.423826e-01 | 0.266 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 5.423826e-01 | 0.266 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 5.433796e-01 | 0.265 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 5.433796e-01 | 0.265 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 5.433796e-01 | 0.265 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 5.451479e-01 | 0.263 | 1 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 5.451479e-01 | 0.263 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 5.451479e-01 | 0.263 | 1 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 5.519972e-01 | 0.258 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 5.521221e-01 | 0.258 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 5.521221e-01 | 0.258 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 5.521221e-01 | 0.258 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 5.524093e-01 | 0.258 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 5.584723e-01 | 0.253 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 5.622860e-01 | 0.250 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 5.622860e-01 | 0.250 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 5.622860e-01 | 0.250 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 5.622860e-01 | 0.250 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 5.622860e-01 | 0.250 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 5.622860e-01 | 0.250 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 5.622860e-01 | 0.250 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 5.622860e-01 | 0.250 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 5.622860e-01 | 0.250 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 5.622860e-01 | 0.250 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 5.622860e-01 | 0.250 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 5.622860e-01 | 0.250 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 5.663331e-01 | 0.247 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 5.663331e-01 | 0.247 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 5.663331e-01 | 0.247 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 5.663331e-01 | 0.247 | 0 | 0 |
| PKA activation | R-HSA-163615 | 5.663331e-01 | 0.247 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 5.663331e-01 | 0.247 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 5.663331e-01 | 0.247 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 5.663331e-01 | 0.247 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 5.663331e-01 | 0.247 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 5.710610e-01 | 0.243 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 5.759797e-01 | 0.240 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 5.759797e-01 | 0.240 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 5.759797e-01 | 0.240 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 5.808085e-01 | 0.236 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 5.831436e-01 | 0.234 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 5.835876e-01 | 0.234 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 5.893655e-01 | 0.230 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 5.893655e-01 | 0.230 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 5.917750e-01 | 0.228 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 5.917750e-01 | 0.228 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 5.970073e-01 | 0.224 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 5.970073e-01 | 0.224 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 5.970073e-01 | 0.224 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 5.970073e-01 | 0.224 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 5.970073e-01 | 0.224 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 5.970073e-01 | 0.224 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 5.970073e-01 | 0.224 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 5.970073e-01 | 0.224 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 6.072173e-01 | 0.217 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 6.072173e-01 | 0.217 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 6.085974e-01 | 0.216 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 6.085974e-01 | 0.216 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 6.085974e-01 | 0.216 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 6.114748e-01 | 0.214 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 6.114748e-01 | 0.214 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 6.114748e-01 | 0.214 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 6.120238e-01 | 0.213 | 1 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 6.132360e-01 | 0.212 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 6.186314e-01 | 0.209 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 6.230286e-01 | 0.205 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 6.247971e-01 | 0.204 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 6.247971e-01 | 0.204 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 6.247971e-01 | 0.204 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 6.287653e-01 | 0.202 | 1 | 0 |
| Lipophagy | R-HSA-9613354 | 6.289762e-01 | 0.201 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 6.289762e-01 | 0.201 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 6.289762e-01 | 0.201 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 6.289762e-01 | 0.201 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 6.289762e-01 | 0.201 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.289762e-01 | 0.201 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 6.289762e-01 | 0.201 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 6.289762e-01 | 0.201 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 6.289762e-01 | 0.201 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 6.289762e-01 | 0.201 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 6.310940e-01 | 0.200 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 6.310940e-01 | 0.200 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 6.326623e-01 | 0.199 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 6.326623e-01 | 0.199 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 6.326623e-01 | 0.199 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 6.326623e-01 | 0.199 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 6.370054e-01 | 0.196 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 6.370054e-01 | 0.196 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 6.370054e-01 | 0.196 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 6.416476e-01 | 0.193 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 6.466120e-01 | 0.189 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 6.482106e-01 | 0.188 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 6.513362e-01 | 0.186 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 6.529352e-01 | 0.185 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 6.529352e-01 | 0.185 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.575982e-01 | 0.182 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 6.579123e-01 | 0.182 | 1 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 6.579577e-01 | 0.182 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 6.579577e-01 | 0.182 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 6.579577e-01 | 0.182 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 6.584109e-01 | 0.182 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 6.584109e-01 | 0.182 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 6.584109e-01 | 0.182 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 6.584109e-01 | 0.182 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 6.584109e-01 | 0.182 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 6.584109e-01 | 0.182 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 6.584109e-01 | 0.182 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 6.584109e-01 | 0.182 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 6.584109e-01 | 0.182 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 6.584109e-01 | 0.182 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 6.587457e-01 | 0.181 | 1 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 6.587457e-01 | 0.181 | 1 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 6.587457e-01 | 0.181 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 6.673288e-01 | 0.176 | 1 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 6.705139e-01 | 0.174 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 6.723053e-01 | 0.172 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 6.723053e-01 | 0.172 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 6.723053e-01 | 0.172 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 6.723053e-01 | 0.172 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 6.723053e-01 | 0.172 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 6.723053e-01 | 0.172 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 6.737253e-01 | 0.172 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 6.765095e-01 | 0.170 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 6.765907e-01 | 0.170 | 1 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 6.765907e-01 | 0.170 | 1 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 6.767183e-01 | 0.170 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 6.810607e-01 | 0.167 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 6.851827e-01 | 0.164 | 1 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 6.851827e-01 | 0.164 | 1 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 6.851948e-01 | 0.164 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 6.851948e-01 | 0.164 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 6.855120e-01 | 0.164 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 6.855120e-01 | 0.164 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 6.855120e-01 | 0.164 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 6.855120e-01 | 0.164 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 6.855120e-01 | 0.164 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 6.889505e-01 | 0.162 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 6.907882e-01 | 0.161 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 6.907882e-01 | 0.161 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 6.907882e-01 | 0.161 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 6.907882e-01 | 0.161 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 6.920204e-01 | 0.160 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 6.920204e-01 | 0.160 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 7.025724e-01 | 0.153 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.034269e-01 | 0.153 | 1 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 7.036359e-01 | 0.153 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 7.082508e-01 | 0.150 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 7.085154e-01 | 0.150 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 7.104644e-01 | 0.148 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 7.104644e-01 | 0.148 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 7.104644e-01 | 0.148 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 7.104644e-01 | 0.148 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 7.104644e-01 | 0.148 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 7.104644e-01 | 0.148 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 7.129535e-01 | 0.147 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 7.160422e-01 | 0.145 | 1 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 7.201485e-01 | 0.143 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 7.251702e-01 | 0.140 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 7.251702e-01 | 0.140 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 7.292073e-01 | 0.137 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 7.292073e-01 | 0.137 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 7.292073e-01 | 0.137 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 7.314047e-01 | 0.136 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 7.314047e-01 | 0.136 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 7.320823e-01 | 0.135 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 7.329608e-01 | 0.135 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 7.334384e-01 | 0.135 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 7.334384e-01 | 0.135 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 7.334384e-01 | 0.135 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.334384e-01 | 0.135 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 7.334384e-01 | 0.135 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 7.334384e-01 | 0.135 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 7.334384e-01 | 0.135 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 7.334384e-01 | 0.135 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 7.334384e-01 | 0.135 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 7.377526e-01 | 0.132 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 7.405771e-01 | 0.130 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 7.405771e-01 | 0.130 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 7.408289e-01 | 0.130 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 7.408289e-01 | 0.130 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 7.411142e-01 | 0.130 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 7.445011e-01 | 0.128 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 7.445011e-01 | 0.128 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 7.445011e-01 | 0.128 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 7.445011e-01 | 0.128 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 7.445011e-01 | 0.128 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 7.445011e-01 | 0.128 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 7.454347e-01 | 0.128 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 7.469226e-01 | 0.127 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 7.545907e-01 | 0.122 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 7.545907e-01 | 0.122 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 7.545907e-01 | 0.122 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 7.545907e-01 | 0.122 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 7.545907e-01 | 0.122 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 7.545907e-01 | 0.122 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 7.545907e-01 | 0.122 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 7.562598e-01 | 0.121 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 7.562598e-01 | 0.121 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 7.562598e-01 | 0.121 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 7.562598e-01 | 0.121 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 7.567797e-01 | 0.121 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 7.627528e-01 | 0.118 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 7.629283e-01 | 0.118 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 7.691593e-01 | 0.114 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 7.691593e-01 | 0.114 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 7.691593e-01 | 0.114 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 7.706332e-01 | 0.113 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 7.706332e-01 | 0.113 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 7.706332e-01 | 0.113 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 7.726800e-01 | 0.112 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 7.726800e-01 | 0.112 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 7.734147e-01 | 0.112 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 7.740657e-01 | 0.111 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 7.740657e-01 | 0.111 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 7.740657e-01 | 0.111 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 7.740657e-01 | 0.111 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 7.740657e-01 | 0.111 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 7.740657e-01 | 0.111 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 7.797835e-01 | 0.108 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 7.798042e-01 | 0.108 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 7.802381e-01 | 0.108 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 7.835323e-01 | 0.106 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 7.842616e-01 | 0.106 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 7.842616e-01 | 0.106 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 7.842616e-01 | 0.106 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 7.867603e-01 | 0.104 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 7.901606e-01 | 0.102 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 7.918391e-01 | 0.101 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 7.918391e-01 | 0.101 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 7.919963e-01 | 0.101 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 7.919963e-01 | 0.101 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 7.919963e-01 | 0.101 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 7.919963e-01 | 0.101 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 7.919963e-01 | 0.101 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 7.919963e-01 | 0.101 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 7.919963e-01 | 0.101 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 7.932871e-01 | 0.101 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 7.950976e-01 | 0.100 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 8.018032e-01 | 0.096 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 8.018032e-01 | 0.096 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 8.024653e-01 | 0.096 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 8.024653e-01 | 0.096 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 8.026855e-01 | 0.095 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 8.059499e-01 | 0.094 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 8.085048e-01 | 0.092 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 8.085048e-01 | 0.092 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 8.085048e-01 | 0.092 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 8.085048e-01 | 0.092 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 8.085048e-01 | 0.092 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 8.085048e-01 | 0.092 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 8.085048e-01 | 0.092 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 8.085048e-01 | 0.092 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 8.085048e-01 | 0.092 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 8.085048e-01 | 0.092 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 8.085048e-01 | 0.092 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 8.085048e-01 | 0.092 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.085048e-01 | 0.092 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 8.093945e-01 | 0.092 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 8.093945e-01 | 0.092 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 8.117343e-01 | 0.091 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 8.153821e-01 | 0.089 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 8.173255e-01 | 0.088 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 8.204406e-01 | 0.086 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 8.204406e-01 | 0.086 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 8.209550e-01 | 0.086 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 8.209550e-01 | 0.086 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 8.223518e-01 | 0.085 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 8.237041e-01 | 0.084 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 8.237041e-01 | 0.084 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 8.237041e-01 | 0.084 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 8.237041e-01 | 0.084 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 8.237041e-01 | 0.084 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 8.237041e-01 | 0.084 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 8.237041e-01 | 0.084 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 8.237041e-01 | 0.084 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 8.280228e-01 | 0.082 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 8.288122e-01 | 0.082 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 8.316381e-01 | 0.080 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 8.318821e-01 | 0.080 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 8.318821e-01 | 0.080 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 8.318821e-01 | 0.080 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 8.358732e-01 | 0.078 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 8.368567e-01 | 0.077 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 8.376978e-01 | 0.077 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 8.376978e-01 | 0.077 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 8.376978e-01 | 0.077 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.376978e-01 | 0.077 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 8.376978e-01 | 0.077 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 8.376978e-01 | 0.077 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 8.389608e-01 | 0.076 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 8.405040e-01 | 0.075 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 8.405040e-01 | 0.075 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 8.405040e-01 | 0.075 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 8.422036e-01 | 0.075 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 8.422036e-01 | 0.075 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 8.422036e-01 | 0.075 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 8.422036e-01 | 0.075 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 8.445823e-01 | 0.073 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 8.445823e-01 | 0.073 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 8.489630e-01 | 0.071 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 8.505815e-01 | 0.070 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 8.505815e-01 | 0.070 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 8.505815e-01 | 0.070 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.505815e-01 | 0.070 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 8.505815e-01 | 0.070 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 8.505815e-01 | 0.070 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 8.508262e-01 | 0.070 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 8.514605e-01 | 0.070 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 8.519467e-01 | 0.070 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 8.519467e-01 | 0.070 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 8.519467e-01 | 0.070 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 8.519972e-01 | 0.070 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 8.570288e-01 | 0.067 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.570288e-01 | 0.067 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 8.591099e-01 | 0.066 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 8.611382e-01 | 0.065 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 8.624431e-01 | 0.064 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 8.624431e-01 | 0.064 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 8.624431e-01 | 0.064 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 8.624431e-01 | 0.064 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 8.624431e-01 | 0.064 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 8.624431e-01 | 0.064 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.624431e-01 | 0.064 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 8.624431e-01 | 0.064 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 8.624431e-01 | 0.064 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 8.624431e-01 | 0.064 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 8.624431e-01 | 0.064 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 8.624431e-01 | 0.064 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 8.659287e-01 | 0.063 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 8.685528e-01 | 0.061 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 8.698042e-01 | 0.061 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 8.698042e-01 | 0.061 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 8.698042e-01 | 0.061 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 8.698042e-01 | 0.061 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 8.698042e-01 | 0.061 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 8.698199e-01 | 0.061 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 8.720348e-01 | 0.059 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 8.724624e-01 | 0.059 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 8.733638e-01 | 0.059 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 8.733638e-01 | 0.059 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 8.733638e-01 | 0.059 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.733638e-01 | 0.059 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 8.733638e-01 | 0.059 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 8.733638e-01 | 0.059 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 8.779702e-01 | 0.057 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 8.779702e-01 | 0.057 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 8.790021e-01 | 0.056 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 8.806475e-01 | 0.055 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 8.830523e-01 | 0.054 | 1 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 8.834181e-01 | 0.054 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 8.834181e-01 | 0.054 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 8.834181e-01 | 0.054 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 8.834181e-01 | 0.054 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 8.834181e-01 | 0.054 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 8.834181e-01 | 0.054 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 8.834181e-01 | 0.054 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 8.847085e-01 | 0.053 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 8.847085e-01 | 0.053 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 8.853050e-01 | 0.053 | 1 | 1 |
| SARS-CoV Infections | R-HSA-9679506 | 8.855932e-01 | 0.053 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 8.856300e-01 | 0.053 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 8.856609e-01 | 0.053 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 8.856609e-01 | 0.053 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 8.856609e-01 | 0.053 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 8.870450e-01 | 0.052 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 8.904381e-01 | 0.050 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 8.904381e-01 | 0.050 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 8.926747e-01 | 0.049 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 8.926747e-01 | 0.049 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 8.926747e-01 | 0.049 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 8.926747e-01 | 0.049 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 8.926747e-01 | 0.049 | 0 | 0 |
| Immune System | R-HSA-168256 | 8.941659e-01 | 0.049 | 1 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 8.959778e-01 | 0.048 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 8.975529e-01 | 0.047 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 8.997116e-01 | 0.046 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 8.998541e-01 | 0.046 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 8.998541e-01 | 0.046 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 8.998541e-01 | 0.046 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 9.011968e-01 | 0.045 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 9.011968e-01 | 0.045 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 9.011968e-01 | 0.045 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 9.036088e-01 | 0.044 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.038829e-01 | 0.044 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 9.041950e-01 | 0.044 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.061170e-01 | 0.043 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.061170e-01 | 0.043 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.061170e-01 | 0.043 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 9.061170e-01 | 0.043 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.082481e-01 | 0.042 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.090427e-01 | 0.041 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.090427e-01 | 0.041 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.090427e-01 | 0.041 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.121381e-01 | 0.040 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 9.140041e-01 | 0.039 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 9.154911e-01 | 0.038 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.162660e-01 | 0.038 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 9.162660e-01 | 0.038 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.162660e-01 | 0.038 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 9.162660e-01 | 0.038 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.162660e-01 | 0.038 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.162660e-01 | 0.038 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.165232e-01 | 0.038 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.177955e-01 | 0.037 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.177955e-01 | 0.037 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.177955e-01 | 0.037 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 9.195157e-01 | 0.036 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 9.217960e-01 | 0.035 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.228422e-01 | 0.035 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 9.229160e-01 | 0.035 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.229160e-01 | 0.035 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.229160e-01 | 0.035 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.229160e-01 | 0.035 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.229160e-01 | 0.035 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.229160e-01 | 0.035 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.229160e-01 | 0.035 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.229160e-01 | 0.035 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 9.231089e-01 | 0.035 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.236003e-01 | 0.035 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 9.239882e-01 | 0.034 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 9.239944e-01 | 0.034 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.279419e-01 | 0.032 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 9.279419e-01 | 0.032 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.279667e-01 | 0.032 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 9.290383e-01 | 0.032 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.290383e-01 | 0.032 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 9.290383e-01 | 0.032 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 9.290383e-01 | 0.032 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.290383e-01 | 0.032 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 9.301384e-01 | 0.031 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.301384e-01 | 0.031 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 9.317091e-01 | 0.031 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 9.321028e-01 | 0.031 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 9.327788e-01 | 0.030 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 9.327788e-01 | 0.030 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 9.327788e-01 | 0.030 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 9.327788e-01 | 0.030 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 9.327788e-01 | 0.030 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 9.346747e-01 | 0.029 | 0 | 0 |
| Cobalamin (Cbl) metabolism | R-HSA-9759218 | 9.346747e-01 | 0.029 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.346747e-01 | 0.029 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 9.346747e-01 | 0.029 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 9.346747e-01 | 0.029 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.346747e-01 | 0.029 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 9.346747e-01 | 0.029 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 9.346747e-01 | 0.029 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.346747e-01 | 0.029 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 9.371706e-01 | 0.028 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 9.371706e-01 | 0.028 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 9.397259e-01 | 0.027 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 9.398637e-01 | 0.027 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 9.398637e-01 | 0.027 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.398637e-01 | 0.027 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 9.398637e-01 | 0.027 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.398637e-01 | 0.027 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.398637e-01 | 0.027 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 9.398637e-01 | 0.027 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 9.405453e-01 | 0.027 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.412893e-01 | 0.026 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 9.446408e-01 | 0.025 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.446408e-01 | 0.025 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.446408e-01 | 0.025 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 9.446408e-01 | 0.025 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.446408e-01 | 0.025 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.446408e-01 | 0.025 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 9.446408e-01 | 0.025 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 9.450582e-01 | 0.025 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 9.451504e-01 | 0.024 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 9.456967e-01 | 0.024 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 9.465498e-01 | 0.024 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 9.474715e-01 | 0.023 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 9.475007e-01 | 0.023 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 9.475007e-01 | 0.023 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 9.480000e-01 | 0.023 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 9.486289e-01 | 0.023 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 9.487689e-01 | 0.023 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 9.490386e-01 | 0.023 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 9.490386e-01 | 0.023 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.490386e-01 | 0.023 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.490386e-01 | 0.023 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.490386e-01 | 0.023 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.505017e-01 | 0.022 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 9.530874e-01 | 0.021 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.530874e-01 | 0.021 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 9.530874e-01 | 0.021 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 9.530874e-01 | 0.021 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 9.533625e-01 | 0.021 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 9.534547e-01 | 0.021 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 9.534554e-01 | 0.021 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 9.540660e-01 | 0.020 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 9.545043e-01 | 0.020 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 9.554492e-01 | 0.020 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.583067e-01 | 0.018 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 9.583067e-01 | 0.018 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 9.601912e-01 | 0.018 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 9.602460e-01 | 0.018 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 9.602460e-01 | 0.018 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 9.605901e-01 | 0.017 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.610893e-01 | 0.017 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.634049e-01 | 0.016 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 9.634049e-01 | 0.016 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 9.636932e-01 | 0.016 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.636932e-01 | 0.016 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 9.651697e-01 | 0.015 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.661291e-01 | 0.015 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.663130e-01 | 0.015 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 9.663130e-01 | 0.015 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 9.663130e-01 | 0.015 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.663130e-01 | 0.015 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.663130e-01 | 0.015 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.663130e-01 | 0.015 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.663130e-01 | 0.015 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.663130e-01 | 0.015 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 9.668111e-01 | 0.015 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 9.677838e-01 | 0.014 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 9.684074e-01 | 0.014 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.686552e-01 | 0.014 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.686552e-01 | 0.014 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.689902e-01 | 0.014 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.689902e-01 | 0.014 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.689902e-01 | 0.014 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.689902e-01 | 0.014 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 9.689902e-01 | 0.014 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.689902e-01 | 0.014 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 9.697158e-01 | 0.013 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 9.706105e-01 | 0.013 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.711084e-01 | 0.013 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 9.714547e-01 | 0.013 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.714547e-01 | 0.013 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.725291e-01 | 0.012 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 9.725747e-01 | 0.012 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 9.736294e-01 | 0.012 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.737235e-01 | 0.012 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.743902e-01 | 0.011 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 9.751160e-01 | 0.011 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 9.751160e-01 | 0.011 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.758121e-01 | 0.011 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 9.758121e-01 | 0.011 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.758121e-01 | 0.011 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.761292e-01 | 0.010 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.768867e-01 | 0.010 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 9.775472e-01 | 0.010 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 9.777348e-01 | 0.010 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.777348e-01 | 0.010 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.777348e-01 | 0.010 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.777348e-01 | 0.010 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 9.777537e-01 | 0.010 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.777537e-01 | 0.010 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.777537e-01 | 0.010 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 9.779373e-01 | 0.010 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.791169e-01 | 0.009 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.792709e-01 | 0.009 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.795047e-01 | 0.009 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 9.795047e-01 | 0.009 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 9.795047e-01 | 0.009 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 9.795047e-01 | 0.009 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.795047e-01 | 0.009 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 9.797560e-01 | 0.009 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 9.806876e-01 | 0.008 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.811341e-01 | 0.008 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 9.817669e-01 | 0.008 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 9.820101e-01 | 0.008 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 9.820101e-01 | 0.008 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 9.825056e-01 | 0.008 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 9.826340e-01 | 0.008 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.826340e-01 | 0.008 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.826340e-01 | 0.008 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.827010e-01 | 0.008 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.836874e-01 | 0.007 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.840148e-01 | 0.007 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.852858e-01 | 0.006 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 9.861047e-01 | 0.006 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.864559e-01 | 0.006 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.864559e-01 | 0.006 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.864559e-01 | 0.006 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.864559e-01 | 0.006 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.864559e-01 | 0.006 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.864739e-01 | 0.006 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 9.864821e-01 | 0.006 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 9.865617e-01 | 0.006 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.867368e-01 | 0.006 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.875329e-01 | 0.005 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 9.877838e-01 | 0.005 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 9.880624e-01 | 0.005 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.882811e-01 | 0.005 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.885244e-01 | 0.005 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.887229e-01 | 0.005 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 9.889461e-01 | 0.005 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.890941e-01 | 0.005 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 9.890941e-01 | 0.005 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.894371e-01 | 0.005 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.898520e-01 | 0.004 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.902772e-01 | 0.004 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.903035e-01 | 0.004 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.903035e-01 | 0.004 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.909205e-01 | 0.004 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.910506e-01 | 0.004 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.912166e-01 | 0.004 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.917625e-01 | 0.004 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 9.920427e-01 | 0.003 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.921229e-01 | 0.003 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.924178e-01 | 0.003 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.924178e-01 | 0.003 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.924178e-01 | 0.003 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 9.925523e-01 | 0.003 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 9.930210e-01 | 0.003 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.933878e-01 | 0.003 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.934292e-01 | 0.003 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.934292e-01 | 0.003 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.934419e-01 | 0.003 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.934419e-01 | 0.003 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.935763e-01 | 0.003 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.937748e-01 | 0.003 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.938988e-01 | 0.003 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.944615e-01 | 0.002 | 1 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.947207e-01 | 0.002 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.949909e-01 | 0.002 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 9.950080e-01 | 0.002 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.950756e-01 | 0.002 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.953895e-01 | 0.002 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.953895e-01 | 0.002 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 9.956360e-01 | 0.002 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 9.962085e-01 | 0.002 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.964051e-01 | 0.002 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.964051e-01 | 0.002 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.966012e-01 | 0.001 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.966698e-01 | 0.001 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.969546e-01 | 0.001 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.970930e-01 | 0.001 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.971971e-01 | 0.001 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.972764e-01 | 0.001 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.974707e-01 | 0.001 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.979062e-01 | 0.001 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.981489e-01 | 0.001 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.982000e-01 | 0.001 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.982551e-01 | 0.001 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.983051e-01 | 0.001 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 9.983554e-01 | 0.001 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 9.984320e-01 | 0.001 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.985569e-01 | 0.001 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.985569e-01 | 0.001 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.986049e-01 | 0.001 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.986345e-01 | 0.001 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.987776e-01 | 0.001 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 9.988176e-01 | 0.001 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.989646e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.989658e-01 | 0.000 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.989658e-01 | 0.000 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.991929e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.991929e-01 | 0.000 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.992025e-01 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.993202e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.994447e-01 | 0.000 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.996483e-01 | 0.000 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 9.997075e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.997205e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.997259e-01 | 0.000 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.997259e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.998034e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.998487e-01 | 0.000 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.998590e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.998601e-01 | 0.000 | 1 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.998902e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999013e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.999043e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999333e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999404e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999544e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999595e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.999774e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999774e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.999801e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.999828e-01 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.999828e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999868e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999887e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999934e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999940e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999972e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.999986e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999986e-01 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.999991e-01 | 0.000 | 1 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999992e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999996e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999996e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.999997e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999998e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999998e-01 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.999998e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
