JNK1

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities

T Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown

Download
substrate_uniprot site source substrate_genes site_seq
A0MZ66 S444 Sugiyama SHTN1 KIAA1598 RPVNQTARPKTKPESSKGCEsAVDELKGILGtLNKSTSSRs
A0MZ66 S494 Sugiyama SHTN1 KIAA1598 EtELERILRRRKVtAEADsssPtGILAtsEsKsMPVLGsVs
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 T789 Sugiyama POTEF A26C1B YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPVLLTEAT
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A5A3E0 Y1062 Sugiyama POTEF A26C1B GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______
A5A3E0 Y791 Sugiyama POTEF A26C1B MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPVLLTEATLN
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NKT7 T1475 Sugiyama RGPD3 RGP3 DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
O00151 S130 Sugiyama PDLIM1 CLIM1 CLP36 PQEVLHIGsAHNRsAMPFtAsPAsSTTARVItNQyNNPAGL
O00161 S110 Sugiyama SNAP23 TKNFEsGKAYKttWGDGGENsPCNVVSKQPGPVTNGQLQQP
O00165 S153 Sugiyama HAX1 HS1BP1 PDSHQPRIFGGVLESDARSEsPQPAPDWGsQRPFHRFDDVW
O00232 S335 Sugiyama PSMD12 MRWSTLVEDYGMELRKGsLEsPAtDVFGsTEEGEKRWKDLK
O00267 T806 Sugiyama SUPT5H SPT5 SPT5H MYGsQtPLQDGsRtPHyGsQtPLHDGsRtPAQsGAWDPNNP
O00418 S396 iPTMNet EEF2K LsENSGDENMSDVTFDsLPSsPsSATPHSQKLDHLHWPVFS
O00429 S126 Sugiyama DNM1L DLP1 DRP1 EIRQEIENETERISGNNKGVsPEPIHLKIFSPNVVNLTLVD
O00499 T323 Sugiyama BIN1 AMPHL sPAAtPEIRVNHEPEPAGGAtPGAtLPKsPsQLRKGPPVPP
O14497 S363 Sugiyama ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1 AAAAAAASGGAQQRsHHAPMsPGssGGGGQPLARtPQPssP
O14497 S698 Sugiyama ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1 QSPFSPHTSPHLPGIRGPsPsPVGsPAsVAQSRsGPLsPAA
O14497 S702 Sugiyama ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1 SPHTSPHLPGIRGPsPsPVGsPAsVAQSRsGPLsPAAVPGN
O14545 T323 Sugiyama TRAFD1 FLN29 ELLIDHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQNFLQ
O14639 S431 Sugiyama ABLIM1 ABLIM KIAA0059 LIMAB1 TSGYDDKQERQsLGEsPRtLsPtPsAEGyQDVRDRMIHRst
O14715 T1474 Sugiyama RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3 DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
O14745 S280 Sugiyama NHERF1 NHERF SLC9A3R1 tNGEIQKENsREALAEAALEsPRPALVRsAssDtsEELNsQ
O14910 S130 Sugiyama LIN7A MALS1 VELI1 ELPKTDEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLK
O14979 S241 Sugiyama HNRNPDL HNRPDL JKTBP KRAKALKGKEPPKKVFVGGLsPDtsEEQIKEYFGAFGEIEN
O43242 S430 Sugiyama PSMD3 ISLSySRIsLADIAQKLQLDsPEDAEFIVAKAIRDGVIEAs
O43379 S1070 Sugiyama WDR62 C19orf14 LPQtPEQEKFLRHHFETLtEsPCRALGDVEASEAEDHFFNP
O43379 T1053 SIGNOR|PSP WDR62 C19orf14 TEDELSLPEGPSVPsssLPQtPEQEKFLRHHFETLtEsPCR
O43521 S104 SIGNOR|ELM|EPSD BCL2L11 BIM RRSsLLSRsssGYFsFDTDRsPAPMSCDKSTQtPsPPCQAF
O43521 S118 SIGNOR|ELM BCL2L11 BIM sFDTDRsPAPMSCDKSTQtPsPPCQAFNHYLSAMASMRQAE
O43521 S69 SIGNOR|EPSD BCL2L11 BIM GGEGDSCPHGsPQGPLAPPAsPGPFATRsPLFIFMRRSsLL
O43521 S77 SIGNOR BCL2L11 BIM HGsPQGPLAPPAsPGPFATRsPLFIFMRRSsLLSRsssGYF
O43521 T116 SIGNOR|ELM BCL2L11 BIM YFsFDTDRsPAPMSCDKSTQtPsPPCQAFNHYLSAMASMRQ
O43524 S574 EPSD|PSP FOXO3 FKHRL1 FOXO3A VsNMGLSESSSLGSAKHQQQsPVSQSMQTLSDSLsGSSLYS
O43561 T184 SIGNOR LAT VLPDSTPATSTAAPSAPALStPGIRDSAFSMESIDDyVNVP
O43765 S77 Sugiyama SGTA SGT SGT1 TLPEIFEAAATGKEMPQDLRsPARtPPsEEDsAEAERLKTE
O43765 T81 Sugiyama SGTA SGT SGT1 IFEAAATGKEMPQDLRsPARtPPsEEDsAEAERLKTEGNEQ
O43852 S261 Sugiyama CALU RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK
O43852 T65 Sugiyama CALU FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD
O43852 Y263 Sugiyama CALU KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
O60282 S176 SIGNOR KIF5C KIAA0531 NKHC2 VHEDKNRVPYVKGCTERFVSsPEEVMDVIDEGKANRHVAVT
O60291 S457 Sugiyama MGRN1 KIAA0544 RNF156 LDSSRQKGRPQSKAPDstLRsPssPIHEEDEEKLsEDVDAP
O60291 S460 Sugiyama MGRN1 KIAA0544 RNF156 SRQKGRPQSKAPDstLRsPssPIHEEDEEKLsEDVDAPPPL
O60333 T647 Sugiyama KIF1B KIAA0591 KIAA1448 GKNHVFRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELL
O60333 T652 Sugiyama KIF1B KIAA0591 KIAA1448 FRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELLEKQGI
O60361 S107 Sugiyama NME2P1 GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDY
O60361 S110 Sugiyama NME2P1 RGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDYKSC
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60568 S367 Sugiyama PLOD3 WPQLQDHFSAVKLVGPEEALsPGEARDMAMDLCRQDPECEF
O60701 T185 Sugiyama UGDH EGTAIKDLKNPDRVLIGGDEtPEGQRAVQALCAVYEHWVPR
O75116 S425 Sugiyama ROCK2 KIAA0619 GNQLPFIGFTYYRENLLLsDsPSCRETDSIQSRKNEESQEI
O75179 S2041 Sugiyama ANKRD17 GTAR KIAA0697 NTAPTNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPL
O75179 Y2038 Sugiyama ANKRD17 GTAR KIAA0697 SNNNTAPTNATYPMPTAKEHyPVssPssPsPPAQPGGVsRN
O75369 S2325 Sugiyama FLNB FLN1L FLN3 TABP TAP PAsFAIRLNGAKGKIDAKVHsPsGAVEECHVsELEPDKYAV
O75376 S158 Sugiyama NCOR1 KIAA1047 RASADAKKDPAFGGKHEAPssPIsGQPCGDDQNAsPsKLSK
O75391 S158 Sugiyama SPAG7 LKELAQRQEEEAAQQGPVVVsPAsDyKDKYSHLIGKGAAKD
O75533 S488 Sugiyama SF3B1 SAP155 KPDDIQYFDKLLVDVDEstLsPEEQKERKIMKLLLKIKNGT
O75533 T207 Sugiyama SF3B1 SAP155 AAAsQPPsKRKRRWDQtADQtPGAtPKKLssWDQAEtPGHt
O75533 T223 Sugiyama SF3B1 SAP155 tADQtPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsE
O75533 T227 Sugiyama SF3B1 SAP155 tPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsEtPGA
O75822 T109 Sugiyama EIF3J EIF3S1 PRO0391 KKRQEEIKKRLEEPEEPKVLtPEEQLADKLRLKKLQEEsDL
O94842 S174 Sugiyama TOX4 C14orf92 KIAA0737 GLSLGGGTILPPAQSPEDRLsttPsPtssLHEDGVEDFRRQ
O94842 S178 Sugiyama TOX4 C14orf92 KIAA0737 GGGTILPPAQSPEDRLsttPsPtssLHEDGVEDFRRQLPSQ
O94842 T176 Sugiyama TOX4 C14orf92 KIAA0737 SLGGGTILPPAQSPEDRLsttPsPtssLHEDGVEDFRRQLP
O94868 S693 Sugiyama FCHSD2 KIAA0769 SH3MD3 RssLYFPRsPsANEKsLHAEsPGFsQAsRHtPETSYGKLRP
O94979 S188 Sugiyama SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334 PEDISCIAWNRQVQHILAsAsPsGRATVWDLRKNEPIIKVS
O95140 S27 SIGNOR MFN2 CPRP1 KIAA0214 RCNsIVtVKKNKRHMAEVNAsPLKHFVTAKKKINGIFEQLG
O95149 S348 Sugiyama SNUPN RNUT1 SPN1 AsENGHyELEHLstPKLKGssHsPDHPGCLMEN________
O95359 T2514 Sugiyama TACC2 DYPQPSDLSTFVNETKFssPtEELDyRNsYEIEyMEKIGss
O95433 Y223 Sugiyama AHSA1 C14orf3 HSPC322 KIPTCKITLKETFLTSPEELyRVFTTQELVQAFTHAPATLE
O95644 S172 EPSD|PSP NFATC1 NFAT2 NFATC PstATLSLPsLEAYRDPsCLsPAssLSSRSCNSEAsSYESN
O95757 S599 Sugiyama HSPA4L APG1 HSPH3 OSP94 sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND
O95757 Y600 Sugiyama HSPA4L APG1 HSPH3 OSP94 IDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERNDA
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00367 T409 Sugiyama GLUD1 GLUD TKSNAPRVKAKIIAEGANGPttPEADKIFLERNIMVIPDLY
P00558 S390 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 IIGGGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPG
P00558 S399 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558 T376 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG
P00558 T378 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA
P00558 T394 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL
P01106 S77 iPTMNet|PSP MYC BHLHE39 PPAPSEDIWKKFELLPtPPLsPsRRsGLCsPSyVAVTPFsL
P01106 S86 iPTMNet|PSP MYC BHLHE39 KKFELLPtPPLsPsRRsGLCsPSyVAVTPFsLRGDNDGGGG
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 T344 Sugiyama ALDOA ALDA AQEEYVKRALANsLACQGKytPsGQAGAAAsEsLFVsNHAy
P04075 T49 Sugiyama ALDOA ALDA GILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtADDR
P04083 S170 Sugiyama ANXA1 ANX1 LPC1 RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE
P04083 S34 Sugiyama ANXA1 ANX1 LPC1 IENEEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKA
P04083 S37 Sugiyama ANXA1 ANX1 LPC1 EEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKAIMV
P04150 S226 SIGNOR|ELM|iPTMNet|EPSD|PSP NR3C1 GRL KETNEsPWRSDLLIDENCLLsPLAGEDDSFLLEGNSNEDCK
P04181 T39 Sugiyama OAT HSSVASATSVATKKtVQGPPtSDDIFEREyKyGAHNyHPLP
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04406 Y320 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____
P04637 S20 SIGNOR|EPSD|PSP TP53 P53 _MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQAM
P04637 T81 SIGNOR|iPTMNet|EPSD|PSP TP53 P53 DEAPRMPEAAPPVAPAPAAPtPAAPAPAPSWPLSSSVPSQK
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05067 T743 SIGNOR APP A4 AD1 LKKKQYtsIHHGVVEVDAAVtPEERHLSKMQQNGyENPtyK
P05187 S177 Sugiyama ALPP PLAP RAKKAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADVP
P05198 T279 Sugiyama EIF2S1 EIF2A KEKIEEKRGVFNVQMEPKVVtDtDEtELARQMERLERENAE
P05386 S101 Sugiyama RPLP1 RRP1 APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S102 Sugiyama RPLP2 D11S2243E RPP2 PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05387 S17 Sugiyama RPLP2 D11S2243E RPP2 ____MRyVAsyLLAALGGNssPsAKDIKKILDsVGIEADDD
P05387 S29 Sugiyama RPLP2 D11S2243E RPP2 LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK
P05412 S63 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP JUN ADPVGSLKPHLRAKNsDLLtsPDVGLLKLAsPELERLIIQS
P05412 S73 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP JUN LRAKNsDLLtsPDVGLLKLAsPELERLIIQSSNGHItttPt
P05412 T91 EPSD|PSP JUN LAsPELERLIIQSSNGHItttPtPtQFLCPKNVTDEQEGFA
P05412 T93 EPSD|PSP JUN sPELERLIIQSSNGHItttPtPtQFLCPKNVTDEQEGFAEG
P05787 S432 EPSD|PSP KRT8 CYK8 HtKTTSGYAGGLSSAYGGLtsPGLSYSLGSSFGSGAGSSSF
P05787 S74 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP KRT8 CYK8 YGGASGMGGITAVtVNQSLLsPLVLEVDPNIQAVRTQEKEQ
P06733 S263 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GMDVAASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsF
P06733 S272 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI
P06733 S37 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 Y280 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06744 S455 Sugiyama GPI ALMRGKSTEEARKELQAAGKsPEDLERLLPHKVFEGNRPTN
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07205 S390 Sugiyama PGK2 PGKB VIGGGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPG
P07205 S399 Sugiyama PGK2 PGKB CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205 T394 Sugiyama PGK2 PGKB GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL
P07237 S449 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB ANEVEAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKF
P07237 T453 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB EAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKFLESG
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07437 T72 Sugiyama TUBB TUBB5 OK/SW-cl.56 NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
P07437 Y50 Sugiyama TUBB TUBB5 OK/SW-cl.56 IDPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEP
P07741 S30 Sugiyama APRT EQRIRsFPDFPTPGVVFRDIsPVLKDPASFRAAIGLLARHL
P07814 S1350 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 YRRRLLsVNIRVRADLRDNysPGWKFNHWELKGVPIRLEVG
P07814 S739 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV
P07814 S886 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPEAKVLFD
P07814 T294 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 ETIMKYAEKLIQEGKAyVDDtPAEQMKAEREQRIDSKHRKN
P07814 T737 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EKTKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRV
P07814 T898 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PLsQssDssPtRNsEPAGLEtPEAKVLFDKVAsQGEVVRKL
P07858 S216 Sugiyama CTSB CPSB PPCTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSE
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07900 S391 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P07900 S50 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL
P07900 T305 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IDQEELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLA
P08047 T278 GPS6|SIGNOR|EPSD|PSP SP1 TSFP1 VALNGNITLLPVNSVSAATLtPSSQAVTISSSGSQESGSQP
P08047 T739 SIGNOR|EPSD|PSP SP1 TSFP1 LsVGtLPLDsGAGsEGSGtAtPSALITTNMVAMEAICPEGI
P08195 S598 Sugiyama SLC3A2 MDU1 LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08195 S607 Sugiyama SLC3A2 MDU1 ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP
P08195 T599 Sugiyama SLC3A2 MDU1 QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH
P08238 S383 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P08238 S417 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB QsKILKVIRKNIVKKCLELFsELAEDKENyKKFyEAFSKNL
P08238 S45 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 T297 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IDQEELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLA
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T89 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08708 S89 Sugiyama RPS17 RPS17L ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL
P08865 T97 Sugiyama RPSA LAMBR LAMR1 IssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQAAFR
P09104 S37 Sugiyama ENO2 NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09382 S63 Sugiyama LGALS1 CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09923 S174 Sugiyama ALPI RAKQAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMP
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG38 T789 Sugiyama POTEI YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
P0CG38 Y1062 Sugiyama POTEI GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG38 Y791 Sugiyama POTEI MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAPLN
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 T752 Sugiyama POTEJ YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
P0CG39 Y1025 Sugiyama POTEJ GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG39 Y754 Sugiyama POTEJ MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAPLN
P0DJD0 T1459 Sugiyama RGPD1 RANBP2L6 RGP1 DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
P0DPH7 S48 Sugiyama TUBA3C TUBA2 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7 T51 Sugiyama TUBA3C TUBA2 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P10070 T1546 PSP GLI2 THP SGALSPSLLHSLSQNSSRLTtPRNSLTLPSIPAGISNMAVG
P10275 S651 EPSD|PSP AR DHTR NR3C4 KLKKLGNLKLQEEGEAsSttsPTEETTQKLTVSHIEGYECQ
P10276 S445 EPSD|PSP RARA NR1B1 GQPGGGGRDGGGLAPPPGsCsPsLsPSSNRSSPATHsP___
P10276 S461 EPSD|PSP RARA NR1B1 PGsCsPsLsPSSNRSSPATHsP___________________
P10276 T181 EPSD|PSP RARA NR1B1 DRNKKKKEVPKPECSESYTLtPEVGELIEKVRKAHQETFPA
P10415 S70 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP BCL2 SSQPGHtPHPAASRDPVARtsPLQtPAAPGAAAGPALsPVP
P10415 S87 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP BCL2 ARtsPLQtPAAPGAAAGPALsPVPPVVHLTLRQAGDDFSRR
P10415 T69 GPS6|SIGNOR|iPTMNet|EPSD|PSP BCL2 FSSQPGHtPHPAASRDPVARtsPLQtPAAPGAAAGPALsPV
P10809 S453 Sugiyama HSPD1 HSP60 EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK
P10809 S70 Sugiyama HSPD1 HSP60 AVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLKDKY
P10809 T455 Sugiyama HSPD1 HSP60 GIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLKIP
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T38 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11532 S3613 Sugiyama DMD LRQLLEQPQAEAKVNGttVssPstsLQRsDssQPMLLRVVG
P11802 T172 EPSD|PSP CDK4 GTVKLADFGLARIYSYQMALtPVVVTLWYRAPEVLLQSTYA
P12270 S2155 Sugiyama TPR PstPtLVVPHRtDGFAEAIHsPQVAGVPRFRFGPPEDMPQT
P13489 S290 Sugiyama RNH1 PRI RNH AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13804 S192 Sugiyama ETFA sFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPEL
P13807 S723 Sugiyama GYS1 GYS TSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN______
P13807 S727 Sugiyama GYS1 GYS KRNsVDtAtsssLstPsEPLsPtssLGEERN__________
P13807 T721 Sugiyama GYS1 GYS sSTSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN____
P13929 S37 Sugiyama ENO3 NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P14314 S442 Sugiyama PRKCSH G19P1 EYVYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSA
P14314 S445 Sugiyama PRKCSH G19P1 YRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKy
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14314 T492 Sugiyama PRKCSH G19P1 WQGPNRstTVRLLCGKEtMVtStTEPSRCEYLMELMTPAAC
P14550 S211 Sugiyama AKR1A1 ALDR1 ALR LAQNELIAHCQARGLEVTAysPLGSSDRAWRDPDEPVLLEE
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S37 Sugiyama PKM OIP3 PK2 PK3 PKM2 QLHAAMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRs
P14618 T195 Sugiyama PKM OIP3 PK2 PK3 PKM2 yVDDGLISLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAA
P14618 T365 SIGNOR|PSP PKM OIP3 PK2 PK3 PKM2 GsDVANAVLDGADCIMLSGEtAKGDyPLEAVRMQHLIAREA
P14625 S106 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625 S523 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 RtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAG
P14625 S552 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 KEKQDKIyFMAGsSRKEAEssPFVERLLKKGyEVIyLTEPV
P14649 S87 Sugiyama MYL6B MLC1SA EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK
P14866 S101 Sugiyama HNRNPL HNRPL P/OKcl.14 GAAGGGGGGENyDDPHKtPAsPVVHIRGLIDGVVEADLVEA
P14868 S369 Sugiyama DARS1 DARS PIG40 CEALAMLREAGVEMGDEDDLstPNEKLLGHLVKEKyDTDFy
P15311 S535 Sugiyama EZR VIL2 EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN
P15311 T533 Sugiyama EZR VIL2 NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII
P15336 S90 EPSD|PSP ATF2 CREB2 CREBP1 PtPtRFLKNCEEVGLFNELAsPFENEFKKASEDDIKKMPLD
P15336 T69 SIGNOR|EPSD|PSP|Sugiyama ATF2 CREB2 CREBP1 HEMtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELA
P15336 T71 GPS6|SIGNOR|EPSD|PSP|Sugiyama ATF2 CREB2 CREBP1 MtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELAsP
P15374 S130 Sugiyama UCHL3 KMHFESGSTLKKFLEEsVsMsPEERARyLENyDAIRVtHEt
P16104 S140 SIGNOR H2AX H2AFX KtsAtVGPKAPSGGKKAtQAsQEy_________________
P16278 S434 Sugiyama GLB1 ELNR1 GFVLYRTTLPQDCSNPAPLssPLNGVHDRAyVAVDGIPQGV
P16949 S38 SIGNOR|Sugiyama STMN1 C1orf215 LAP18 OP18 QAFELILsPRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAE
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17275 T102 SIGNOR|iPTMNet|EPSD|PSP JUNB LASSELERLIVPNSNGVITttPtPPGQyFYPRGGGsGGGAG
P17275 T104 SIGNOR|iPTMNet|EPSD|PSP JUNB SSELERLIVPNSNGVITttPtPPGQyFYPRGGGsGGGAGGA
P17535 S100 SIGNOR|EPSD|PSP JUND SAAPPDGLLAsPDLGLLKLAsPELERLIIQSNGLVtttPTS
P17544 T51 Sugiyama ATF7 ATFA HEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELA
P17544 T53 Sugiyama ATF7 ATFA MTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELASS
P17706 S298 Sugiyama PTPN2 PTPT CIKGDSSIQKRWKELsKEDLsPAFDHsPNKIMtEKYNGNRI
P17812 S575 Sugiyama CTPS1 CTPS LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____
P17936 S97 Sugiyama IGFBP3 IBP3 EGQPCGIYTERCGSGLRCQPsPDEARPLQALLDGRGLCVNA
P17980 S376 Sugiyama PSMC3 TBP1 MPNEEARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQC
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669 S31 Sugiyama PGAM1 PGAMA CDABP0006 HGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALRDAGyE
P18669 T146 Sugiyama PGAM1 PGAMA CDABP0006 MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF
P18754 S90 Sugiyama RCC1 CHC1 VQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsVEGSEM
P19419 S383 GPS6|SIGNOR ELK1 tPVLLtPSSLPPSIHFWSTLsPIAPRsPAKLSFQFPSSGSA
P19419 S389 SIGNOR ELK1 PSSLPPSIHFWSTLsPIAPRsPAKLSFQFPSSGSAQVHIPS
P19793 S260 SIGNOR|EPSD|PSP RXRA NR2B1 LAVEPKTETyVEANMGLNPssPNDPVtNICQAADKQLFTLV
P20290 T182 Sugiyama BTF3 NACB OK/SW-cl.8 LRRLAEALPKQsVDGKAPLAtGEDDDDEVPDLVENFDEAsK
P20618 S151 Sugiyama PSMB1 PSC5 PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA
P20618 Y150 Sugiyama PSMB1 PSC5 FPYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSAS
P21333 S1084 Sugiyama FLNA FLN FLN1 PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV
P21333 S1459 Sugiyama FLNA FLN FLN1 KVPVHDVTDASKVKCsGPGLsPGMVRANLPQsFQVDTSKAG
P21333 S2319 Sugiyama FLNA FLN FLN1 VQEPGDyEVsVKFNEEHIPDsPFVVPVAsPsGDARRLtVss
P21333 S2327 Sugiyama FLNA FLN FLN1 VsVKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKV
P21333 S2329 Sugiyama FLNA FLN FLN1 VKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKVNQ
P22059 T332 Sugiyama OSBP OSBP1 AKQHNHLERAFRGAtVLPANtPGNVGsGKDQCCSGKGDMsD
P22059 T762 Sugiyama OSBP OSBP1 KQRLSRKKREAEAMKATEDGtPYDPyKALWFERKKDPVTKE
P22234 S27 Sugiyama PAICS ADE2 AIRC PAIS LNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAGNAARK
P22314 T233 Sugiyama UBA1 A1S9T UBE1 GEQPLSAMVSMVTKDNPGVVtCLDEARHGFESGDFVSFSEV
P22392 S122 Sugiyama NME2 NM23B GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDy
P22392 S125 Sugiyama NME2 NM23B RGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDyKSC
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P22626 S259 Sugiyama HNRNPA2B1 HNRPA2B1 GFGDGyNGyGGGPGGGNFGGsPGyGGGRGGYGGGGPGYGNQ
P22736 S95 SIGNOR|EPSD|PSP NR4A1 GFRP1 HMR NAK1 VQPCSSASSSASSTSSSSATsPASASFKFEDFQVYGCYPGP
P23246 T687 Sugiyama SFPQ PSF FGQGGAGPVGGQGPRGMGPGtPAGyGRGREEYEGPNKKPRF
P23396 T242 Sugiyama RPS3 OK/SW-cl.26 PIsEQKGGKPEPPAMPQPVPtA___________________
P23528 Y140 Sugiyama CFL1 CFL SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs
P23921 S559 Sugiyama RRM1 RR1 ALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTPTDLW
P24534 S8 Sugiyama EEF1B2 EEF1B EF1B _____________MGFGDLKsPAGLQVLNDyLADKSYIEGY
P24752 S218 Sugiyama ACAT1 ACAT MAT ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV
P24928 S1913 Sugiyama POLR2A POLR2 PtysPtsPVytPtsPKysPtsPtysPtsPKysPtsPtysPt
P24928 S1917 Sugiyama POLR2A POLR2 PtsPVytPtsPKysPtsPtysPtsPKysPtsPtysPtsPKG
P24928 T1912 Sugiyama POLR2A POLR2 sPtysPtsPVytPtsPKysPtsPtysPtsPKysPtsPtysP
P25786 S14 Sugiyama PSMA1 HC2 NU PROS30 PSC2 _______MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQGSA
P26038 T465 Sugiyama MSN WQQKAQMVQEDLEKTRAELKtAMstPHVAEPAENEQDEQDE
P26038 T469 Sugiyama MSN AQMVQEDLEKTRAELKtAMstPHVAEPAENEQDEQDENGAE
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26640 S301 Sugiyama VARS1 G7A VARS VARS2 DLPtPPGEKKDVSGPMPDsysPRYVEAAWYPWWEQQGFFKP
P27816 S507 Sugiyama MAP4 APAKDVAPSTVKEVGLLKDMsPLsEtEMALGKDVtPPPEtE
P28066 S179 Sugiyama PSMA5 sGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSL
P28074 S175 Sugiyama PSMB5 LMPX MB1 X SMGTMICGWDKRGPGLyyVDsEGNRISGATFSVGSGSVYAY
P28324 S381 GPS6 ELK4 SAP1 tPIILtPSPLLSSIHFWSTLsPVAPLsPARLQGANTLFQFP
P28324 S387 GPS6 ELK4 SAP1 PSPLLSSIHFWSTLsPVAPLsPARLQGANTLFQFPSVLNSH
P28324 S425 GPS6 ELK4 SAP1 NSHGPFTLSGLDGPStPGPFsPDLQKT______________
P28324 T361 GPS6 ELK4 SAP1 LGILSPSLPTASLTPAFFSQtPIILtPSPLLSSIHFWSTLs
P28324 T366 GPS6 ELK4 SAP1 PSLPTASLTPAFFSQtPIILtPSPLLSSIHFWSTLsPVAPL
P28324 T420 GPS6 ELK4 SAP1 FPSVLNSHGPFTLSGLDGPStPGPFsPDLQKT_________
P28715 S384 Sugiyama ERCC5 ERCM2 XPG XPGC ENRRQARGRNAPAAVDEGsIsPRtLSAIKRALDDDEDVKVC
P29401 S105 Sugiyama TKT VWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGsL
P29401 S295 Sugiyama TKT ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI
P29401 T287 Sugiyama TKT AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP
P29474 S114 PSP NOS3 CTPRRCLGSLVFPRKLQGRPsPGPPAPEQLLSQARDFINQY
P29692 S133 Sugiyama EEF1D EF1D NVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPAEDDE
P29692 S162 Sugiyama EEF1D EF1D AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY
P29692 S64 Sugiyama EEF1D EF1D sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI
P29692 T147 Sugiyama EEF1D EF1D PQtQHVsPMRQVEPPAKKPAtPAEDDEDDDIDLFGsDNEEE
P29966 S101 Sugiyama MARCKS MACS PRKCSL sPsAAEKGEPAAAAAPEAGAsPVEKEAPAEGEAAEPGsPtA
P29966 S27 Sugiyama MARCKS MACS PRKCSL KTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAsP
P29966 S46 EPSD|PSP MARCKS MACS PRKCSL ssPsKANGQENGHVKVNGDAsPAAAEsGAKEELQANGsAPA
P30041 T177 Sugiyama PRDX6 AOP2 KIAA0106 FDEILRVVISLQLTAEKRVAtPVDWKDGDsVMVLPtIPEEE
P30043 S82 Sugiyama BLVRB FLR SCAN DKTVAGQDAVIVLLGTRNDLsPTTVMSEGARNIVAAMKAHG
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050 S157 Sugiyama RPL12 QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P30050 S165 Sugiyama RPL12 GRHPHDIIDDINsGAVECPAs____________________
P30050 S26 Sugiyama RPL12 DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI
P30086 T42 Sugiyama PEBP1 PBP PEBP QHPLHVTYAGAAVDELGKVLtPtQVKNRPtsIsWDGLDsGK
P30086 T69 Sugiyama PEBP1 PBP PEBP RPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWHHFLV
P30086 Y64 Sugiyama PEBP1 PBP PEBP tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW
P30101 S443 Sugiyama PDIA3 ERP57 ERP60 GRP58 LsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLN
P30101 Y115 Sugiyama PDIA3 ERP57 ERP60 GRP58 yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA
P30305 S101 SIGNOR CDC25B CDC25HU2 SRSRLTHLsLsRRASESSLSsEsSESSDAGLCMDSPSPMDP
P30305 S103 SIGNOR CDC25B CDC25HU2 SRLTHLsLsRRASESSLSsEsSESSDAGLCMDSPSPMDPHM
P30307 S168 SIGNOR|EPSD|PSP CDC25C SANKENDNGNLVDSEMKYLGsPITTVPKLDKNPNLGEDQAE
P31749 T450 SIGNOR AKT1 PKB RAC TSETDTRYFDEEFtAQMItItPPDQDDSMECVDSERRPHFP
P31943 S104 Sugiyama HNRNPH1 HNRPH HNRPH1 EVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK
P31943 T100 Sugiyama HNRNPH1 HNRPH HNRPH1 HRyVEVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPF
P31946 S186 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP YWHAB HPIRLGLALNFSVFYYEILNsPEKACSLAKTAFDEAIAELD
P31947 S186 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP SFN HME1 NPIRLGLALNFSVFHYEIANsPEEAISLAKTtFDEAMADLH
P31948 S481 Sugiyama STIP1 CKEAADGYQRCMMAQyNRHDsPEDVKRRAMADPEVQQIMSD
P32322 S294 Sugiyama PYCR1 QEQVSPAAIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLA
P32322 S301 Sugiyama PYCR1 AIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLAPAGKD__
P32322 T298 Sugiyama PYCR1 SPAAIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLAPAGK
P33176 S175 Sugiyama KIF5B KNS KNS1 VHEDKNRVPYVKGCTERFVCsPDEVMDtIDEGKSNRHVAVT
P33991 S131 Sugiyama MCM4 CDC21 PVRQRPDLGsAQKGLQVDLQsDGAAAEDIVAsEQsLGQKLV
P33992 S315 Sugiyama MCM5 CDC46 RVLGIQVDTDGSGRSFAGAVsPQEEEEFRRLAALPNVYEVI
P33992 S398 Sugiyama MCM5 CDC46 LMLGDPGTAKSQLLKFVEKCsPIGVytsGKGSSAAGLtAsV
P34896 T405 Sugiyama SHMT1 NKNTCPGDRSALRPSGLRLGtPALTSRGLLEKDFQKVAHFI
P34897 S417 Sugiyama SHMT2 ERVLELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFR
P34897 T420 Sugiyama SHMT2 LELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFREDD
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P34931 T40 Sugiyama HSPA1L VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P35222 S33 EPSD|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 AMEPDRKAAVsHWQQQsyLDsGIHsGATtTAPsLsGKGNPE
P35222 S37 SIGNOR|EPSD|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 DRKAAVsHWQQQsyLDsGIHsGATtTAPsLsGKGNPEEEDV
P35222 T41 SIGNOR|EPSD|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 AVsHWQQQsyLDsGIHsGATtTAPsLsGKGNPEEEDVDTsQ
P35269 T389 Sugiyama GTF2F1 RAP74 PPKRERKPsGGSSRGNsRPGtPsAEGGstsstLRAAASKLE
P35568 S307 GPS6|SIGNOR IRS1 HHLNNPPPSQVGLTRRsRtEsItAtsPAsMVGGKPGsFRVR
P35568 S312 SIGNOR|iPTMNet|EPSD|PSP IRS1 PPPSQVGLTRRsRtEsItAtsPAsMVGGKPGsFRVRAssDG
P35568 S315 SIGNOR IRS1 SQVGLTRRsRtEsItAtsPAsMVGGKPGsFRVRAssDGEGt
P35568 S616 SIGNOR IRS1 GGHHRPDsstLHtDDGyMPMsPGVAPVPSGRKGsGDyMPMs
P35568 S636 SIGNOR IRS1 sPGVAPVPSGRKGsGDyMPMsPKsVSAPQQIINPIRRHPQR
P35606 T828 Sugiyama COPB2 EEWVKETHADLWPAKQyPLVtPNEERNVMEEGKDFQPSRst
P35658 S430 Sugiyama NUP214 CAIN CAN KIAA0023 VKSLIKTPERLsLEGERQPKsPGstPTTPTSSQAPQKLDAS
P35658 S433 Sugiyama NUP214 CAIN CAN KIAA0023 LIKTPERLsLEGERQPKsPGstPTTPTSSQAPQKLDASAAA
P35658 T434 Sugiyama NUP214 CAIN CAN KIAA0023 IKTPERLsLEGERQPKsPGstPTTPTSSQAPQKLDASAAAA
P35813 S216 Sugiyama PPM1A PPPM1A ALGDFDYKCVHGKGPTEQLVsPEPEVHDIERSEEDDQFIIL
P35998 T193 Sugiyama PSMC2 MSS1 TYSDVGGCKEQIEKLREVVEtPLLHPERFVNLGIEPPKGVL
P36956 S117 EPSD|PSP SREBF1 BHLHD1 SREBP1 LSPPQPAPTPLKMYPSMPAFsPGPGIKEESVPLSILQTPTP
P37231 S112 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP PPARG NR1C3 DYKYDLKLQEyQSAIKVEPAsPPYYSEKTQLYNKPHEEPSN
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T87 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKR
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P38936 S130 SIGNOR|iPTMNet|EPSD|PSP CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 HVDLsLSCTLVPRsGEQAEGsPGGPGDSQGRKRRQtsMTDF
P38936 S98 EPSD|PSP CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 LPtGPRRGRDELGGGRRPGtsPALLQGTAEEDHVDLsLSCT
P38936 T57 SIGNOR|iPTMNet|EPSD|PSP CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 LMAGCIQEARERWNFDFVtEtPLEGDFAWERVRGLGLPKLy
P40222 S514 Sugiyama TXLNA TXLN GsLtDsGPERRPEGPGAQAPssPRVtEAPCyPGAPSTEASG
P40763 S727 SIGNOR|EPSD|PSP STAT3 APRF KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS
P41091 T109 Sugiyama EIF2S3 EIF2G YKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLVRH
P41970 S357 ELM|iPTMNet ELK3 NET SAP2 NGLLLTPSPLLSSIHFWSSLsPVAPLsPARLQGPSTLFQFP
P42166 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs
P42167 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS
P42224 Y701 SIGNOR STAT1 YSRPKEAPEPMELDGPKGtGyIKtELIsVsEVHPSRLQttD
P42226 S707 SIGNOR|EPSD|PSP STAT6 DMVPQVYPPHSHSIPPYQGLsPEESVNVLSAFQEPHLQMPP
P43121 T107 Sugiyama MCAM MUC18 EYEQRLsLQDRGAtLALtQVtPQDERIFLCQGKRPRSQEYR
P45983 S179 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C VKSDCTLKILDFGLARTAGtsFMMtPyVVtRyYRAPEVILG
P45983 S270 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C KKLQPTVRTYVENRPKyAGysFEKLFPDVLFPADsEHNKLK
P45983 S284 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C PKyAGysFEKLFPDVLFPADsEHNKLKASQARDLLSKMLVI
P45983 T178 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C VVKSDCTLKILDFGLARTAGtsFMMtPyVVtRyYRAPEVIL
P45983 T183 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C CTLKILDFGLARTAGtsFMMtPyVVtRyYRAPEVILGMGYK
P45983 T188 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C LDFGLARTAGtsFMMtPyVVtRyYRAPEVILGMGYKENVDL
P45983 T243 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C ILFPGRDYIDQWNKVIEQLGtPCPEFMKKLQPTVRTYVENR
P45983 Y185 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C LKILDFGLARTAGtsFMMtPyVVtRyYRAPEVILGMGYKEN
P45983 Y266 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C PEFMKKLQPTVRTYVENRPKyAGysFEKLFPDVLFPADsEH
P45983 Y269 Sugiyama MAPK8 JNK1 PRKM8 SAPK1 SAPK1C MKKLQPTVRTYVENRPKyAGysFEKLFPDVLFPADsEHNKL
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46937 S138 GPS6|SIGNOR YAP1 YAP65 LtPQHVRAHssPAsLQLGAVsPGtLtPtGVVsGPAAtPTAQ
P46937 S367 GPS6|SIGNOR|Sugiyama YAP1 YAP65 ALRSQLPtLEQDGGtQNPVssPGMsQELRTMttNssDPFLN
P46937 S400 SIGNOR YAP1 YAP65 NssDPFLNsGtyHsRDEstDsGLsMssysVPRtPDDFLNsV
P46937 T110 Sugiyama YAP1 YAP65 KLPDsFFKPPEPKsHsRQAstDAGtAGALtPQHVRAHssPA
P46937 T119 GPS6|SIGNOR|Sugiyama YAP1 YAP65 PEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQLGAVsP
P46937 T154 GPS6|SIGNOR|PSP YAP1 YAP65 LGAVsPGtLtPtGVVsGPAAtPTAQHLRQssFEIPDDVPLP
P46937 T412 GPS6|EPSD YAP1 YAP65 HsRDEstDsGLsMssysVPRtPDDFLNsVDEMDTGDTINQS
P47756 S207 Sugiyama CAPZB MNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKIRst
P47914 S142 Sugiyama RPL29 KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___
P48506 S215 Sugiyama GCLC GLCL GLCLC HRRGEKVVINVPIFKDKNtPsPFIETFTEDDEASRASKPDH
P48506 T213 Sugiyama GCLC GLCL GLCLC IRHRRGEKVVINVPIFKDKNtPsPFIETFTEDDEASRASKP
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P49023 S106 Sugiyama PXN PVyGssAKtssVsNPQDsVGsPCsRVGEEEHVysFPNKQKs
P49023 S178 SIGNOR|iPTMNet|EPSD|PSP PXN NPPGFPADEANSSPPLPGALsPLyGVPETNSPLGGKAGPLT
P49023 S303 Sugiyama PXN QRADGERCWAAGWPRDGGRssPGGQDEGGFMAQGKtGsssP
P49321 T390 Sugiyama NASP EAPVLPKDGAVNGPsVVGDQtPIEPQtsIERLtEtKDGsGL
P49448 T409 Sugiyama GLUD2 GLUDP1 TKSNAPRVKAKIIAEGANGPttPEADKIFLERNILVIPDLY
P49643 T470 Sugiyama PRIM2 PRIM2A ESQRILNGGKDIKKEPIQPEtPQPKPsVQKTKDASSALASL
P49721 S76 Sugiyama PSMB2 FAEYIQKNVQLYKMRNGYELsPTAAANFTRRNLADCLRSRT
P49753 S360 Sugiyama ACOT2 PTE2 PTE2A NRNRIKVTKDGyADIVDVLNsPLEGPDQKSFIPVERAESTF
P49757 S634 Sugiyama NUMB C14orf41 DPFEAQWAALENKSKQRtNPsPtNPFSSDLQKTFEIEL___
P49792 S1400 Sugiyama RANBP2 NUP358 PSNKELVGPPLAEtVFtPKtsPENVQDRFALVtPKKEGHWD
P49792 T1396 Sugiyama RANBP2 NUP358 QNLNPSNKELVGPPLAEtVFtPKtsPENVQDRFALVtPKKE
P49792 T1761 Sugiyama RANBP2 NUP358 ATKCIACQCPSKQNQtTAIstPAssEIsKAPKsGFEGMFIR
P49792 T2450 Sugiyama RANBP2 NUP358 DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
P49841 T43 Sugiyama GSK3B FGsMKVSRDKDGSKVTTVVAtPGQGPDRPQEVSyTDTKVIG
P49915 S332 Sugiyama GMPS IsDEDRtPRKRISKTLNMttsPEEKRKIIGDTFVKIANEVI
P50454 S139 Sugiyama SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS
P50454 S141 Sugiyama SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI
P51812 S715 Sugiyama RPS6KA3 ISPK1 MAPKAPK1B RSK2 APHLVKGAMAAtysALNRNQsPVLEPVGRsTLAQRRGIKKI
P51991 S358 Sugiyama HNRNPA3 HNRPA3 QQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF
P52272 S701 Sugiyama HNRNPM HNRPM NAGR1 yADIKMENGKSKGCGVVKFEsPEVAERACRMMNGMKLSGRE
P52565 T160 Sugiyama ARHGDIA GDIA1 DKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYsIKSR
P52948 S623 Sugiyama NUP98 ADAR2 KNLNNsNLFsPVNRDsENLAsPsEyPENGERFsFLSKPVDE
P53396 S481 Sugiyama ACLY ADEVAPAKKAKPAMPQDsVPsPRSLQGKSTTLFSRHTKAIV
P53779 S217 Sugiyama MAPK10 JNK3 JNK3A PRKM10 SAPK1B VKSDCTLKILDFGLARTAGtsFMMtPyVVtRyYRAPEVILG
P53779 T216 Sugiyama MAPK10 JNK3 JNK3A PRKM10 SAPK1B VVKSDCTLKILDFGLARTAGtsFMMtPyVVtRyYRAPEVIL
P53779 T221 Sugiyama MAPK10 JNK3 JNK3A PRKM10 SAPK1B CTLKILDFGLARTAGtsFMMtPyVVtRyYRAPEVILGMGYK
P53779 T226 Sugiyama MAPK10 JNK3 JNK3A PRKM10 SAPK1B LDFGLARTAGtsFMMtPyVVtRyYRAPEVILGMGYKENVDI
P53779 T281 Sugiyama MAPK10 JNK3 JNK3A PRKM10 SAPK1B ILFPGRDYIDQWNKVIEQLGtPCPEFMKKLQPTVRNYVENR
P53779 Y223 Sugiyama MAPK10 JNK3 JNK3A PRKM10 SAPK1B LKILDFGLARTAGtsFMMtPyVVtRyYRAPEVILGMGYKEN
P54105 T223 Sugiyama CLNS1A CLCI ICLN AGVRtEDsIRDyEDGMEVDttPtVAGQFEDADVDH______
P54259 S739 GPS6|SIGNOR|EPSD|PSP ATN1 D12S755E DRPLA PPLSATQIKQEPAEEyEtPEsPVPPARsPsPPPKVVDVPSH
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T39 Sugiyama HSPA2 VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P54727 T155 Sugiyama RAD23B SEPAPASAAKQEKPAEKPAEtPVAtsPtAtDstsGDssRSN
P54727 T162 Sugiyama RAD23B AAKQEKPAEKPAEtPVAtsPtAtDstsGDssRSNLFEDATS
P55036 S115 Sugiyama PSMD4 MCB1 LALKHRQGKNHKMRIIAFVGsPVEDNEKDLVKLAKRLKKEK
P55060 T341 Sugiyama CSE1L CAS XPO2 LASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEA
P55072 T76 Sugiyama VCP HEL-220 HEL-S-70 TVLLKGKKRREAVCIVLSDDtCSDEKIRMNRVVRNNLRVRL
P55209 T62 Sugiyama NAP1L1 NRP MMQNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALK
P55795 S104 Sugiyama HNRNPH2 FTP3 HNRPH2 EVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK
P55795 T100 Sugiyama HNRNPH2 FTP3 HNRPH2 HRyVEVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPF
P55809 S509 Sugiyama OXCT1 OXCT SCOT LWEGLTVDDVQKSTGCDFAVsPKLMPMQQIAN_________
P55957 T59 EPSD|PSP BID ALGHELPVLAPQWEGyDELQtDGNRssHsRLGRIEADsEsQ
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T214 Sugiyama TPI1 TPI KsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGG
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60660 S30 Sugiyama MYL6 AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 T202 Sugiyama ACTB GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T318 Sugiyama ACTB VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709 T89 Sugiyama ACTB YPIEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAP
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y362 Sugiyama ACTB GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P60709 Y91 Sugiyama ACTB IEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAPLN
P60866 T6 Sugiyama RPS20 _______________MAFKDtGKtPVEPEVAIHRIRITLTS
P61247 S237 Sugiyama RPS3A FTE1 MFTL MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 S32 Sugiyama RPL26 sKNRKRHFNAPsHIRRKIMssPLSKELRQKYNVRSMPIRKD
P61604 S64 Sugiyama HSPE1 AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD
P61916 S40 Sugiyama NPC2 HE1 EPVQFKDCGsVDGVIKEVNVsPCPtQPCQLSKGQSYSVNVT
P61978 S216 SIGNOR|EPSD|PSP HNRNPK HNRPK GGKPDRVVECIKIILDLIsEsPIKGRAQPyDPNFyDETyDy
P61978 S284 Sugiyama HNRNPK HNRPK MPPGRGGRPMPPSRRDyDDMsPRRGPPPPPPGRGGRGGsRA
P61978 S353 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP HNRNPK HNRPK YDGMVGFSADETWDSAIDtWsPSEWQMAYEPQGGSGYDYSY
P61978 S77 Sugiyama HNRNPK HNRPK VIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIETI
P62195 T109 Sugiyama PSMC5 SUG1 VHPEGKFVVDVDKNIDINDVtPNCRVALRNDsytLHKILPN
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 T208 Sugiyama YWHAE PDRACRLAKAAFDDAIAELDtLsEEsyKDstLIMQLLRDNL
P62263 S137 Sugiyama RPS14 PRO2640 RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______
P62263 T133 Sugiyama RPS14 PRO2640 QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62714 S212 Sugiyama PPP2CB EGPMCDLLWSDPDDRGGWGIsPRGAGYTFGQDISETFNHAN
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T320 Sugiyama ACTA2 ACTSA ACTVS GIG46 VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62750 S43 Sugiyama RPL23A KAKKAVLKGVHSHKKKKIRtsPTFRRPKTLRLRRQPKYPRK
P62829 S115 Sugiyama RPL23 FLYFEDNAGVIVNNKGEMKGsAItGPVAKECADLWPRIASN
P62829 T118 Sugiyama RPL23 FEDNAGVIVNNKGEMKGsAItGPVAKECADLWPRIASNAGs
P62899 T119 Sugiyama RPL31 PNKLytLVtyVPVttFKNLQtVNVDEN______________
P62942 S9 Sugiyama FKBP1A FKBP1 FKBP12 ____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG
P63104 S184 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP YWHAZ HPIRLGLALNFSVFYYEILNsPEKACSLAKtAFDEAIAELD
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 T202 Sugiyama ACTG1 ACTG GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T318 Sugiyama ACTG1 ACTG VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261 T89 Sugiyama ACTG1 ACTG YPIEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAP
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y362 Sugiyama ACTG1 ACTG GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P63261 Y91 Sugiyama ACTG1 ACTG IEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAPLN
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T319 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67775 S212 Sugiyama PPP2CA EGPMCDLLWSDPDDRGGWGIsPRGAGYTFGQDISETFNHAN
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T320 Sugiyama ACTC1 ACTC VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032 T91 Sugiyama ACTC1 ACTC yPIEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAP
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 Y93 Sugiyama ACTC1 ACTC IEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAPLN
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T320 Sugiyama ACTA1 ACTA VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133 T91 Sugiyama ACTA1 ACTA yPIEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAP
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68133 Y93 Sugiyama ACTA1 ACTA IEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAPLN
P68363 S48 Sugiyama TUBA1B HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363 T51 Sugiyama TUBA1B QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T80 Sugiyama TUBA1B KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P78316 S96 Sugiyama NOP14 C4orf9 NOL14 RES4-25 ERDKSNVFRDKRFGEyNsNMsPEEKMMKRFALEQQRHHEKK
P78371 T474 Sugiyama CCT2 99D8.1 CCTB AGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGIT
P80723 T36 Sugiyama BASP1 NAP22 DEKAKEKDKKAEGAAtEEEGtPKEsEPQAAAEPAEAKEGKE
P85037 T436 Sugiyama FOXK1 MNF sAPAsPtHPGLMsPRsGGLQtPECLsREGsPIPHDPEFGsK
P85298 S455 SIGNOR|EPSD|PSP ARHGAP8 LQEAVPRTQATGLTKPTLPPsPLMAARRRL___________
P98177 S230 SIGNOR|EPSD|PSP FOXO4 AFX AFX1 MLLT7 KAPKKKPSVLPAPPEGAtPtsPVGHFAKWSGSPCSRNREEA
P98177 T227 SIGNOR|EPSD|PSP FOXO4 AFX AFX1 MLLT7 GRSKAPKKKPSVLPAPPEGAtPtsPVGHFAKWSGSPCSRNR
P98177 T451 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP FOXO4 AFX AFX1 MLLT7 LSMIAPPPVMASAPIPKALGtPVLtPPTEAASQDRMPQDLD
P98177 T455 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP FOXO4 AFX AFX1 MLLT7 APPPVMASAPIPKALGtPVLtPPTEAASQDRMPQDLDLDMY
Q00610 S886 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 IHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsRVVG
Q00613 S363 SIGNOR|ELM|iPTMNet HSF1 HSTF1 AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE
Q01082 T2192 Sugiyama SPTBN1 SPTB2 sDRKAKTALPAQsAAtLPARtQEtPsAQMEGFLNRKHEWEA
Q01082 T2195 Sugiyama SPTBN1 SPTB2 KAKTALPAQsAAtLPARtQEtPsAQMEGFLNRKHEWEAHNK
Q01130 S212 Sugiyama SRSF2 SFRS2 PPPVsKRESKSRSRsKsPPKsPEEEGAVss___________
Q01814 S1231 Sugiyama ATP2B2 PMCA2 SAIDSGINLTTDtsKSATSSsPGsPIHSLEtsL________
Q01814 S1234 Sugiyama ATP2B2 PMCA2 DSGINLTTDtsKSATSSsPGsPIHSLEtsL___________
Q01844 T79 PSP EWSR1 EWS ATYGQTAYATSYGQPPTGYttPtAPQAYSQPVQGYGTGAYD
Q02952 S483 Sugiyama AKAP12 AKAP250 LVKLKEtCVsGEDPTQGADLsPDEKVLSKPPEGVVSEVEML
Q02952 S569 Sugiyama AKAP12 AKAP250 QVPADsPDsQEEQKGEssAssPEEPEEItCLEKGLAEVQQD
Q05639 S205 SIGNOR|EPSD|PSP EEF1A2 EEF1AL STN PATVPFVPISGWHGDNMLEPsPNMPWFKGWKVERKEGNASG
Q05639 S358 SIGNOR|EPSD|PSP EEF1A2 EEF1AL STN AQFTSQVIILNHPGQISAGYsPVIDCHTAHIACKFAELKEK
Q06481 T736 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP APLP2 APPL2 LRKRQYGtISHGIVEVDPMLtPEERHLNKMQNHGyENPtyK
Q07020 S130 Sugiyama RPL18 RSRILRAGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYR
Q07020 T122 Sugiyama RPL18 ALRVTSRARSRILRAGGKILtFDQLALDsPKGCGtVLLsGP
Q07021 T165 Sugiyama C1QBP GC1QBP HABP1 SF2P32 GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD
Q07157 S1619 Sugiyama TJP1 ZO1 KPKyQINNISTVPKAIPVsPsAVEEDEDEDGHTVVATARGI
Q07157 S912 Sugiyama TJP1 ZO1 NQtyPPYsPQAQPQPIHRIDsPGFKPAsQQKAEAssPVPyL
Q07817 S62 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP BCL2L1 BCL2L BCLX ESEMEtPsAINGNPSWHLADsPAVNGATGHSSSLDAREVIP
Q07817 T115 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP BCL2L1 BCL2L BCLX DEFELRYRRAFSDLTSQLHItPGTAYQSFEQVVNELFRDGV
Q07817 T47 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP BCL2L1 BCL2L BCLX FSDVEENRTEAPEGTESEMEtPsAINGNPSWHLADsPAVNG
Q07820 S121 EPSD|PSP MCL1 BCL2L3 PTRRAAPLEEMEAPAADAIMsPEEELDGYEPEPLGKRPAVL
Q07820 S64 GPS6|EPSD|PSP MCL1 BCL2L3 ARREIGGGEAGAVIGGSAGAsPPstLtPDSRRVARPPPIGA
Q07820 T163 SIGNOR|EPSD|PSP MCL1 BCL2L3 LLELVGEsGNNtstDGsLPstPPPAEEEEDELYRQSLEIIS
Q07866 S460 Sugiyama KLC1 KLC KNS2 QKDGTsFGEyGGWyKACKVDsPtVTTtLKNLGALyRRQGKF
Q07960 S51 Sugiyama ARHGAP1 CDC42GAP RHOGAP1 KNWPsDEMPDFPKsDDsKsssPELVtHLKWDDPyyDIARHQ
Q08AD1 S673 Sugiyama CAMSAP2 CAMSAP1L1 KIAA1078 DASKFLQDyDIRTGNTREALsPCPsTVsTKSQPGSSAssss
Q08J23 S743 Sugiyama NSUN2 SAKI TRM4 AstGQPDNDVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGV
Q08J23 S751 Sugiyama NSUN2 SAKI TRM4 DVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGVHPPR____
Q09666 T3716 Sugiyama AHNAK PM227 VEGDLKGPEVDIKGPKVDIDtPDINIEGsEGKFKGPKFKIP
Q09666 T4100 Sugiyama AHNAK PM227 VDVNLPKADIDVsGPKVDIDtPDIDIHGPEGKLKGPKFKMP
Q12765 S322 Sugiyama SCRN1 KIAA0193 RSIFKPFIFVDDVKLVPKtQsPCFGDDDPAKKEPRFQEKPD
Q12765 T320 Sugiyama SCRN1 KIAA0193 PSRSIFKPFIFVDDVKLVPKtQsPCFGDDDPAKKEPRFQEK
Q12774 S445 Sugiyama ARHGEF5 TIM ASYLMTQIPGTQTESRAEELsPAALsPsLEPIRCSHQPISL
Q12774 S450 Sugiyama ARHGEF5 TIM TQIPGTQTESRAEELsPAALsPsLEPIRCSHQPISLLGsFL
Q12792 S143 Sugiyama TWF1 PTK9 GTVKEDVSLHGYKKyLLsQssPAPLtAAEEELRQIKINEVQ
Q12888 S380 Sugiyama TP53BP1 sDLVAPsPDAFRstPFIVPssPtEQEGRQDKPMDtsVLsEE
Q12904 S140 SIGNOR|EPSD|PSP AIMP1 EMAP2 SCYE1 EKKAKEKIEKKGEKKEKKQQsIAGsADSKPIDVSRLDLRIG
Q12931 S568 Sugiyama TRAP1 HSP75 HSPC5 ISVETDIVVDHYKEEKFEDRsPAAECLSEKETEELMAWMRN
Q12965 T1011 Sugiyama MYO1E MYO1C sMARPPLPRQQstssDRVsQtPEsLDFLKVPDQGAAGVRRQ
Q13043 S82 SIGNOR|EPSD|PSP STK4 KRS2 MST1 PVEsDLQEIIKEIsIMQQCDsPHVVKYYGSYFKNTDLWIVM
Q13200 S16 Sugiyama PSMD2 TRAP2 _____MEEGGRDKAPVQPQQsPAAAPGGtDEKPsGKERRDA
Q13263 S512 Sugiyama TRIM28 KAP1 RNF96 TIF1B RLDLDLtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATG
Q13263 T513 Sugiyama TRIM28 KAP1 RNF96 TIF1B LDLDLtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATGQ
Q13263 T514 Sugiyama TRIM28 KAP1 RNF96 TIF1B DLDLtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATGQP
Q13283 S230 Sugiyama G3BP1 G3BP IQEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFs
Q13283 S231 Sugiyama G3BP1 G3BP QEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsW
Q13283 S232 Sugiyama G3BP1 G3BP EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA
Q13283 T241 Sugiyama G3BP1 G3BP ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP
Q13363 S422 SIGNOR|EPSD|PSP CTBP1 CTBP PSAMSLSHGLPPVAHPPHAPsPGQTVKPEADRDHASDQL__
Q13409 S92 Sugiyama DYNC1I2 DNCI2 DNCIC2 ESPIVFSEYWVPPPMsPSSKsVStPsEAGsQDsGDGAVGsR
Q13409 S97 Sugiyama DYNC1I2 DNCI2 DNCIC2 FSEYWVPPPMsPSSKsVStPsEAGsQDsGDGAVGsRTLHWD
Q13438 S653 Sugiyama OS9 AQKERQRQKELESNYRRVWGsPGGEGTGDLDEFDF______
Q13442 S19 Sugiyama PDAP1 HASPP28 __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE
Q13443 S758 Sugiyama ADAM9 KIAA0021 MCMP MDC9 MLTNG SDGKNQANPSRQPGsVPRHVsPVtPPREVPIyANRFAVPty
Q13443 T761 Sugiyama ADAM9 KIAA0021 MCMP MDC9 MLTNG KNQANPSRQPGsVPRHVsPVtPPREVPIyANRFAVPtyAAK
Q13451 S13 Sugiyama FKBP5 AIG6 FKBP51 ________MttDEGAKNNEEsPtAtVAEQGEDITsKKDRGV
Q13451 T46 Sugiyama FKBP5 AIG6 FKBP51 TsKKDRGVLKIVKRVGNGEEtPMIGDKVyVHYKGKLSNGKK
Q13459 S1290 Sugiyama MYO9B MYR5 EtPEDKsKPCGsPRVQEKPDsPGGstQIQRYLDAERLAsAV
Q13501 S266 Sugiyama SQSTM1 ORCA OSIL AALsPLGIEVDIDVEHGGKRsRLtPVsPEssstEEKsssQP
Q13501 S272 Sugiyama SQSTM1 ORCA OSIL GIEVDIDVEHGGKRsRLtPVsPEssstEEKsssQPssCCsD
Q13501 T269 Sugiyama SQSTM1 ORCA OSIL sPLGIEVDIDVEHGGKRsRLtPVsPEssstEEKsssQPssC
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13509 T72 Sugiyama TUBB3 TUBB4 NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF
Q13526 S115 SIGNOR|PSP PIN1 KIKSGEEDFEsLAsQFSDCSsAKARGDLGAFsRGQMQKPFE
Q13541 S83 Sugiyama EIF4EBP1 RNsPVtKtPPRDLPtIPGVtsPssDEPPMEAsQsHLRNsPE
Q13573 S224 Sugiyama SNW1 SKIIP SKIP KDPMEPPRFKINKKIPRGPPsPPAPVMHsPsRKMTVKEQQE
Q13573 S234 Sugiyama SNW1 SKIIP SKIP INKKIPRGPPsPPAPVMHsPsRKMTVKEQQEWKIPPCISNW
Q13610 S57 Sugiyama PWP1 AEAKEKLQEEGGGsDEEEtGsPsEDGMQsARTQARPREPLE
Q13884 S87 Sugiyama SNTB1 SNT2B1 SFCRGAGAGHPGAGGAQPPDsPAGVRTAFTDLPEQVPESIS
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q13885 T72 Sugiyama TUBB2A TUBB2 NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q13950 S118 EPSD|PSP RUNX2 AML3 CBFA1 OSF2 PEBP2A DNRTMVEIIADHPAELVRTDsPNFLCSVLPSHWRCNKTLPV
Q14103 S190 Sugiyama HNRNPD AUF1 HNRPD KRAKAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVES
Q14103 T193 Sugiyama HNRNPD AUF1 HNRPD KAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVESIEL
Q14135 S149 Sugiyama VGLL4 KIAA0121 LEQPLALTKNsLDAsRPAGLsPtLtPGERQQNRPSVITCAS
Q14135 T153 Sugiyama VGLL4 KIAA0121 LALTKNsLDAsRPAGLsPtLtPGERQQNRPSVITCASAGAR
Q14137 T106 Sugiyama BOP1 KIAA0124 LDDEGHSGIKKTTEEQVQAstPCPRTEMASARIGDEyAEDs
Q14157 S416 Sugiyama UBAP2L KIAA0144 NICE4 tQsPsLVQYDLKNPsDsAVHsPFtKRQAFtPsstMMEVFLQ
Q14157 S470 Sugiyama UBAP2L KIAA0144 NICE4 PPPssPLPsKstsAPQMsPGssDNQsssPQPAQQKLKQQKK
Q14160 S1232 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL AAGIGHRNsLEsIssIDRELsPEGPGKEKELPGQTLHWGPE
Q14160 S1486 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL RHQERLRVQsPEPPAPERALsPAELRALEAEKRALWRAARM
Q14160 S504 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL MKRSIEGRRsEACPCQPDsGsPLPAEEEKRLsAESGLSEDS
Q14204 S2410 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 GEDEAQRRRKGKEDEGEEAAsPMLQIQRDAATIMQPYFTSN
Q14204 T1882 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 ANAKFNyGFEyLGVQDKLVQtPLTDRCyLTMTQALEARLGG
Q14247 S405 Sugiyama CTTN EMS1 EEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVyEDAA
Q14247 S418 Sugiyama CTTN EMS1 KtQtPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVs
Q14451 S194 SIGNOR|EPSD|PSP GRB7 GGDSRFVFRKNFAKyELFKssPHSLFPEKMVSSCLDAHTGI
Q14568 S50 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL
Q14653 S173 SIGNOR|EPSD|PSP IRF3 PDPGPPSLAVAPEPCPQPLRsPsLDNPtPFPNLGPsENPLK
Q14677 S164 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 RLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKW
Q14749 S10 PSP GNMT ___________MVDSVYRtRsLGVAAEGLPDQYADGEAARV
Q14847 T104 Sugiyama LASP1 MLN50 VRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsNIKyHE
Q14934 S213 GPS6|EPSD|PSP NFATC4 NFAT3 AACDEVESELNEAASRFGLGsPLPsPRASPRPWtPEDPWSL
Q14934 S217 GPS6|EPSD|PSP NFATC4 NFAT3 EVESELNEAASRFGLGsPLPsPRASPRPWtPEDPWSLYGPS
Q14974 S12 Sugiyama KPNB1 NTF97 _________MELITILEKtVsPDRLELEAAQKFLERAAVEN
Q14980 S1757 Sugiyama NUMA1 NMP22 NUMA ITSKLPRtQPDGtsVPGEPAsPIsQRLPPKVEsLEsLyFtP
Q14980 T2000 Sugiyama NUMA1 NMP22 NUMA GITTRQQRKRVsLEPHQGPGtPEsKKATSCFPRPMtPRDRH
Q15181 S250 Sugiyama PPA1 IOPPP PP LVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDALPPPC
Q15181 T245 Sugiyama PPA1 IOPPP PP DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA
Q15185 S113 Sugiyama PTGES3 P23 TEBP RAKLNWLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGD
Q15293 T211 Sugiyama RCN1 RCN FTAFLHPEEFEHMKEIVVLEtLEDIDKNGDGFVDQDEyIAD
Q15293 T71 Sugiyama RCN1 RCN EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI
Q15293 T76 Sugiyama RCN1 RCN FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD
Q15393 T1200 Sugiyama SF3B3 KIAA0017 SAP130 EQFNsMEPNKQKNVSEELDRtPPEVSKKLEDIRTRYAF___
Q15599 S43 Sugiyama NHERF2 SLC9A3R2 FHLHGEKGRRGQFIRRVEPGsPAEAAALRAGDRLVEVNGVN
Q15599 T102 Sugiyama NHERF2 SLC9A3R2 QTRLLVVDQETDEELRRRQLtCTEEMAQRGLPPAHDPWEPK
Q15637 S80 Sugiyama SF1 ZFM1 ZNF162 DLTRKLRtGDLGIPPNPEDRsPsPEPIyNsEGKRLNTREFR
Q15637 S82 Sugiyama SF1 ZFM1 ZNF162 TRKLRtGDLGIPPNPEDRsPsPEPIyNsEGKRLNTREFRTR
Q15637 T232 Sugiyama SF1 ZFM1 ZNF162 MENVKKAVEQIRNILKQGIEtPEDQNDLRKMQLRELARLNG
Q15642 S298 Sugiyama TRIP10 CIP4 STOT STP RPGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRT
Q15642 T302 Sugiyama TRIP10 CIP4 STOT STP VEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRTKRWP
Q15654 T27 Sugiyama TRIP6 OIP1 LPPKQPEPARAPQGRAIPRGtPGPPPAHGAALQPHPRVNFC
Q15672 S68 SIGNOR|EPSD|PSP TWIST1 BHLHA38 TWIST GGAGPGGAAGGGVGGGDEPGsPAQGKRGKKSAGCGGGGGAG
Q15717 S221 PSP ELAVL1 HUR HsPARRFGGPVHHQAQRFRFsPMGVDHMSGLSGVNVPGNAS
Q15750 S438 PSP TAB1 MAP3K7IP1 VNGAHsASTLDEAtPTLTNQsPTLTLQSTNTHTQssSSssD
Q15773 S238 Sugiyama MLF2 GAGGRRAEGPPRLAIQGPEDsPsRQsRRYDW__________
Q15814 S330 Sugiyama TBCC RSKNNWNDVDDFNWLARDMAsPNWsILPEEERNIQWD____
Q16204 S244 Sugiyama CCDC6 D10S170 TST1 LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF
Q16236 S215 PSP NFE2L2 NRF2 PELQCLNIENDKLVETtMVPsPEAKLTEVDNYHFYSSIPSM
Q16236 S408 PSP NFE2L2 NRF2 VKQNGPKtPVHSSGDMVQPLsPSQGQSTHVHDAQCENTPEK
Q16236 S577 PSP NFE2L2 NRF2 LstLYLEVFSMLRDEDGKPysPSEYSLQQTRDGNVFLVPKS
Q16513 T121 Sugiyama PKN2 PRK2 PRKCL2 QELNAHIVVsDPEDItDCPRtPDtPNNDPRCSTSNNRLKAL
Q16513 T124 Sugiyama PKN2 PRK2 PRKCL2 NAHIVVsDPEDItDCPRtPDtPNNDPRCSTSNNRLKALQKQ
Q16621 S157 SIGNOR|EPSD|PSP NFE2 KPQEDPESDSGLSLNYSDAEsLELEGTEAGRRRSEYVEMYP
Q16621 S346 PSP NFE2 LTELYRDIFQHLRDESGNSYsPEEYALQQAADGTIFLVPRG
Q16630 T157 Sugiyama CPSF6 CFIM68 SKKLMDLLPKRELHGQNPVVtPCNKQFLsQFEMQSRKTTQS
Q16643 T346 Sugiyama DBN1 D0S117E RRMAPtPIPtRsPsDsstAstPVAEQIERALDEVTsSQPPP
Q16658 S127 Sugiyama FSCN1 FAN1 HSN SNL AHRRYFGGtEDRLsCFAQtVsPAEKWSVHIAMHPQVNIYSV
Q16719 S443 Sugiyama KYNU VVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAET
Q16719 Y448 Sugiyama KYNU RNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAETKN___
Q16881 T413 Sugiyama TXNRD1 GRIM12 KDRF HGIKFIRQFVPIKVEQIEAGtPGRLRVVAQSTNSEEIIEGE
Q4KMP7 T150 Sugiyama TBC1D10B FP2461 ADsPKtEEARPsPAPGPGtPtGtPtRtPsRtAPGALTAKPP
Q4V328 S655 Sugiyama GRIPAP1 KIAA1167 ILTNSKSRSGLEELVLsEMNsPSRtQtGDsssIssFsYREI
Q53EZ4 S425 Sugiyama CEP55 C10orf3 URCC6 ITEPLVTFQGETENREKVAAsPKsPtAALNEsLVECPKCNI
Q53EZ4 T430 Sugiyama CEP55 C10orf3 URCC6 VTFQGETENREKVAAsPKsPtAALNEsLVECPKCNIQYPAT
Q53GS7 S88 PSP GLE1 GLE1L ETSPSSTSASALDQPSFVPKsPDAssAFsPAsPAtPNGTKG
Q53GS7 S92 PSP GLE1 GLE1L SSTSASALDQPSFVPKsPDAssAFsPAsPAtPNGTKGKDES
Q53GS7 S93 PSP GLE1 GLE1L STSASALDQPSFVPKsPDAssAFsPAsPAtPNGTKGKDESQ
Q53GS7 S99 PSP GLE1 GLE1L LDQPSFVPKsPDAssAFsPAsPAtPNGTKGKDESQHTESMV
Q53GS7 T102 PSP GLE1 GLE1L PSFVPKsPDAssAFsPAsPAtPNGTKGKDESQHTESMVLQS
Q562R1 T107 Sugiyama ACTBL2 WYHTFYNELRVAPDEHPILLtEAPLNPKINREKMTQIMFEA
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q5JR12 S93 SIGNOR PPM1J PPP2CZ LQLsPGGLRRADDHAGRAVQsPPDTGRRLPWSTGYAEVINA
Q5JSH3 S50 Sugiyama WDR44 RPH11 KVGLSTFKETENTAYKVGNEsPVQELKQDVSKKIIEsIIEE
Q5JSH3 S96 Sugiyama WDR44 RPH11 QLEDDsLDSKGKELsDQAtAsPIVARTDLSNIPGLLAIDQV
Q5JSH3 T364 Sugiyama WDR44 RPH11 sGRELtDEEILASVMIKNLDtGEEIPLsLAEEKLPTGINPL
Q5JTZ9 T670 Sugiyama AARS2 AARSL KIAA1270 TEQQGSHLNPEQLRLDVTTQtPLtPEQLRAVENTVQEAVGQ
Q5JTZ9 T673 Sugiyama AARS2 AARSL KIAA1270 QGSHLNPEQLRLDVTTQtPLtPEQLRAVENTVQEAVGQDEA
Q5R3I4 S362 Sugiyama TTC38 GAHDPQTTQELLTTLRDASEsPGENCQHLLARDVGLPLCQA
Q5T4S7 S178 Sugiyama UBR4 KIAA0462 KIAA1307 RBAF600 AKLPQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLT
Q5VT52 T723 Sugiyama RPRD2 KIAA0460 HSPC099 SHPSDFQRGPtstsIDNIDGtPVRDERsGtPtQDEMMDKPt
Q66K74 S759 Sugiyama MAP1S BPY2IP1 C19orf5 MAP8 VCY2IP1 LVsPCEFEHRKAVPMAPAPAsPGssNDssARsQERAGGLGA
Q68CZ2 S660 Sugiyama TNS3 TEM6 TENS1 TPP RVAVQRGVGsGPHPPDTQQPsPsKAFKPRFPGDQVVNGAGP
Q6EMK4 S322 Sugiyama VASN SLITL2 UNQ314/PRO357/PRO1282 CVCPLSWFGPWVRESHVTLAsPEETRCHFPPKNAGRLLLEL
Q6FI81 T136 Sugiyama CIAPIN1 CUA001 PRO0915 CSALTLSGLVEVKELQREPLtPEEVQSVREHLGHESDNLLF
Q6JBY9 S216 GPS6|SIGNOR RCSD1 CAPZIP NGAKEEDGDEVLPSKsKAPGsPLssEGAAGEGVRTLGPAEK
Q6JBY9 S68 GPS6|SIGNOR RCSD1 CAPZIP PCSLPLFPPKVDLGQNGEEKsPPNAsHPPKFKVKssPLIEK
Q6JBY9 S83 GPS6|SIGNOR RCSD1 CAPZIP NGEEKsPPNAsHPPKFKVKssPLIEKLQANLTFDPAALLPG
Q6PEY2 S48 Sugiyama TUBA3E HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2 T51 Sugiyama TUBA3E QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q6PKG0 S627 Sugiyama LARP1 KIAA0731 LARP FLFDEEMEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVt
Q6PKG0 S631 Sugiyama LARP1 KIAA0731 LARP EEMEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVtQtPH
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 T789 Sugiyama POTEE A26C1A POTE2 YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6S8J3 Y1062 Sugiyama POTEE A26C1A POTE2 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q6S8J3 Y791 Sugiyama POTEE A26C1A POTE2 MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAPLN
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6SZW1 S548 SIGNOR|PSP SARM1 KIAA0524 SAMD2 SARM GIHLGVHRARILTAAREMLHsPLPCTGGKPSGDTPDVFISY
Q6WCQ1 S326 Sugiyama MPRIP KIAA0864 MRIP RHOIP3 KFEALDIEKAEHMETNAVGPsPssDTRQGRSEKRAFPRKRD
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q71U36 S48 Sugiyama TUBA1A TUBA3 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36 T51 Sugiyama TUBA1A TUBA3 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T80 Sugiyama TUBA1A TUBA3 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q7KZF4 T103 EPSD|PSP SND1 TDRD11 REFLRKKLIGKEVCFtIENKtPQGREyGMIyLGKDTNGENI
Q7L2J0 S217 Sugiyama MEPCE BCDIN3 LNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPKDItD
Q7L2J0 T213 Sugiyama MEPCE BCDIN3 DPLNLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPK
Q7Z2W4 S275 Sugiyama ZC3HAV1 ZC3HDC2 PRO1677 QGsQEFLASASAsAERsCtPsPDQIsHRAsLEDAPVDDLtR
Q7Z2W4 T273 Sugiyama ZC3HAV1 ZC3HDC2 PRO1677 FFQGsQEFLASASAsAERsCtPsPDQIsHRAsLEDAPVDDL
Q7Z3J3 T1475 Sugiyama RGPD4 RGP4 DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
Q7Z417 S692 Sugiyama NUFIP2 KIAA1321 PIG1 IWNLQKQDPKRIItyNEAMDsPDQ_________________
Q7Z4H7 T858 Sugiyama HAUS6 DGT6 FAM29A KIAA1574 EALKKSLSKKREESyLSNsQtPERHKPELsPtPQNVQtDDt
Q7Z4V5 S183 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 KMsVSKRARKASSDLDQAsVsPSEEENSESSsESEKTsDQD
Q7Z6Z7 T2889 Sugiyama HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272 EAVGDTSAAGSSEQPRAGsstPGDAPPAVAEVQGRSDGsGE
Q86TX2 S298 Sugiyama ACOT1 CTE1 NRNRIKVTKDGyADIVDVLNsPLEGPDQKSFIPVERAESTF
Q86UE4 T143 Sugiyama MTDH AEG1 LYRIC SEKPKPNGRTVEVAEGEAVRtPQsVtAKQPPEIDKKNEKSK
Q86UY5 S353 Sugiyama FAM83A TSGP NPFSGRSAGSHPGTRsVsAssGPCsPAAPHPPPPPRFQPHQ
Q86UY5 S357 Sugiyama FAM83A TSGP GRSAGSHPGTRsVsAssGPCsPAAPHPPPPPRFQPHQGPWG
Q86VQ1 T350 Sugiyama GLCCI1 RRAPLPAHYRssstRsIDTQtPsVQERSSSCSSHSPCVSPF
Q86X29 T501 Sugiyama LSR ILDR3 LISCH GGGWRARRPRARsVDALDDLtPPstAEsGsRsPtsNGGRSR
Q8IWW6 S240 Sugiyama ARHGAP12 SSSsTEQIRAttPPNQGRPDsPVyANLQELKISQSALPPLP
Q8IWW6 T231 Sugiyama ARHGAP12 QDSEsGDELSSSsTEQIRAttPPNQGRPDsPVyANLQELKI
Q8N122 S696 EPSD|PSP RPTOR KIAA1303 RAPTOR SNFCTVALQFIEEEKNYALPsPATTEGGSLtPVRDsPCtPR
Q8N122 S863 EPSD|PSP RPTOR KIAA1303 RAPTOR VNARPQRVLDtssLtQsAPAsPtNKGVHIHQAGGsPPAsst
Q8N122 T706 EPSD|PSP RPTOR KIAA1303 RAPTOR IEEEKNYALPsPATTEGGSLtPVRDsPCtPRLRsVssYGNI
Q8N1F7 S430 Sugiyama NUP93 KIAA0095 TEDYLWLKLNQVCFDDDGTssPQDRLTLsQFQKQLLEDYGE
Q8N684 T203 Sugiyama CPSF7 GGIPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLP
Q8N6T7 S10 EPSD|PSP SIRT6 SIR2L6 ___________MSVNYAAGLsPYADKGKCGLPEIFDPPEEL
Q8NBJ5 S612 Sugiyama COLGALT1 GLT25D1 PSEC0241 QKMREQQALSREAKNsDVLQsPLDsAARDEL__________
Q8NBJ5 S616 Sugiyama COLGALT1 GLT25D1 PSEC0241 EQQALSREAKNsDVLQsPLDsAARDEL______________
Q8NBJ7 S44 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 NGQATSMVQLQGGRFLMGtNsPDSRDGDGPVREATVKPFAI
Q8NBJ7 T278 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 IDtADGsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPP
Q8NEY1 S1000 Sugiyama NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1 PsPPALPMSLSAKGQLTNIVsPtAAttPRITRsNsIPTHEA
Q8NEY1 S1377 Sugiyama NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1 DRLKVAPGPSSGstPGQVPGssALssPRRSLGLALTHSFGP
Q8NEY1 T1006 Sugiyama NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1 PMSLSAKGQLTNIVsPtAAttPRITRsNsIPTHEAAFELYS
Q8NEY1 T1370 Sugiyama NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1 DLLKAENDRLKVAPGPSSGstPGQVPGssALssPRRSLGLA
Q8NG08 S1021 Sugiyama HELB SEASSPDERTLTFAERWQLssPDGVDtDDDLPKSRASKRTC
Q8TAQ2 S283 Sugiyama SMARCC2 BAF170 KNPVSRRKKISAKtLtDEVNsPDsDRRDKKGGNYKKRKRsP
Q8TAQ2 S286 Sugiyama SMARCC2 BAF170 VSRRKKISAKtLtDEVNsPDsDRRDKKGGNYKKRKRsPsPs
Q8TC07 S675 Sugiyama TBC1D15 TSAFQSNALPTLSASGARNDsPtQIPVssDVCRLtPA____
Q8TCS8 S754 Sugiyama PNPT1 PNPASE KYFGRDPADGRMRLSRKVLQsPAtTVVRTLNDRssIVMGEP
Q8TD19 S29 Sugiyama NEK9 KIAA1995 NEK8 NERCC RHCDsINSDFGSEsGGCGDssPGPSASQGPRAGGGAAEQEE
Q8WUF5 S567 Sugiyama PPP1R13L IASPP NKIP1 PPP1R13BL RAI ISRLFHRHGGPGPGGPEPELsPItEGSEARAGPPAPAPPAP
Q8WUI4 S109 Sugiyama HDAC7 HDAC7A LAEVILKKQQAALERtVHPNsPGIPYRTLEPLETEGATRSM
Q8WUM4 S730 Sugiyama PDCD6IP AIP1 ALIX KIAA1375 QQsIAREPsAPsIPtPAyQssPAGGHAPtPPtPAPRTMPPT
Q8WUM4 T738 Sugiyama PDCD6IP AIP1 ALIX KIAA1375 sAPsIPtPAyQssPAGGHAPtPPtPAPRTMPPTKPQPPARP
Q8WUM4 T741 Sugiyama PDCD6IP AIP1 ALIX KIAA1375 sIPtPAyQssPAGGHAPtPPtPAPRTMPPTKPQPPARPPPP
Q8WW01 T10 Sugiyama TSEN15 C1orf19 SEN15 ___________MEERGDsEPtPGCSGLGPGGVRGFGDGGGA
Q8WW12 T139 Sugiyama PCNP sEPEEMPPEAKMRMKNIGRDtPtsAGPNsFNKGKHGFsDNQ
Q8WWM7 S111 Sugiyama ATXN2L A2D A2LG A2LP A2RP PGAAAIGsARGQstGKGPPQsPVFEGVyNNSRMLHFLTAVV
Q8WWM7 S589 Sugiyama ATXN2L A2D A2LG A2LP A2RP PRILKEEPKGKEKEVDGLLtsEPMGsPVssKtEsVsDKEDK
Q8WWM7 S594 Sugiyama ATXN2L A2D A2LG A2LP A2RP EEPKGKEKEVDGLLtsEPMGsPVssKtEsVsDKEDKPPLAP
Q8WXI9 S122 Sugiyama GATAD2B KIAA1150 DEPVDMSARRsEPERGRLtPsPDIIVLsDNEAssPRsSsRM
Q8WXI9 S135 Sugiyama GATAD2B KIAA1150 ERGRLtPsPDIIVLsDNEAssPRsSsRMEERLKAANLEMFK
Q8WYK2 T148 GPS6|iPTMNet JDP2 LILMLNRHRPTCIVRTDsVKtPEsEGNPLLEQLEKK_____
Q8WYQ5 S153 EPSD|PSP DGCR8 C22orf12 DGCRK6 LP4941 RKVLYTGAERDVRAECGLLLsPVSGDVHACPFGGSVGDGVG
Q92530 S152 Sugiyama PSMF1 SRIVSGIITPIHEQWEKANVssPHREFPPAtAREVDPLRIP
Q92530 S153 Sugiyama PSMF1 RIVSGIITPIHEQWEKANVssPHREFPPAtAREVDPLRIPP
Q92609 S539 Sugiyama TBC1D5 KIAA0210 KsEsMPVQLNKGLSSKNIsssPsVEsLPGGREFtGsPPssA
Q92614 S164 Sugiyama MYO18A CD245 KIAA0216 MYSPDZ TIAF1 RsRDEsAsEtstPsEHsAAPsPQVEVRTLEGQLVQHPGPGI
Q92871 S242 Sugiyama PMM1 PMMH22 PGGNDFEIFADPRTVGHSVVsPQDtVQRCREIFFPETAHEA
Q92879 S179 Sugiyama CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 AMAQTAIKAMHQAQtMEGCssPMVVKFADTQKDKEQKRMAQ
Q92922 T335 Sugiyama SMARCC1 BAF155 DRKASANARKRKHsPsPPPPtPtEsRKKSGKKGQASLYGKR
Q92945 S181 Sugiyama KHSRP FUBP2 GRGGEQINKIQQDSGCKVQIsPDsGGLPERsVsLtGAPEsV
Q92945 S184 Sugiyama KHSRP FUBP2 GEQINKIQQDSGCKVQIsPDsGGLPERsVsLtGAPEsVQKA
Q93045 S73 PSP STMN2 SCG10 SCGN10 AFELILKPPsPISEAPRTLAsPKKKDLsLEEIQKKLEAAEE
Q969R2 S762 PSP OSBP2 KIAA1664 ORP4 OSBPL4 AHYVLSGSWDEQMECSKVMHssPssPsSDGKQKTVYQTLSA
Q969R2 S763 PSP OSBP2 KIAA1664 ORP4 OSBPL4 HYVLSGSWDEQMECSKVMHssPssPsSDGKQKTVYQTLSAK
Q969R2 S766 PSP OSBP2 KIAA1664 ORP4 OSBPL4 LSGSWDEQMECSKVMHssPssPsSDGKQKTVYQTLSAKLLW
Q969R2 S768 PSP OSBP2 KIAA1664 ORP4 OSBPL4 GSWDEQMECSKVMHssPssPsSDGKQKTVYQTLSAKLLWKK
Q96AE4 S630 Sugiyama FUBP1 DYSAAWAEYYRQQAAyyAQtsPQGMPQHPPAPQGQ______
Q96B36 S212 Sugiyama AKT1S1 PRAS40 GFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAED
Q96C19 S74 Sugiyama EFHD2 SWS1 ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI
Q96D15 T72 Sugiyama RCN3 UNQ239/PRO272 FQYDHEAFLGREVAKEFDQLtPEEsQARLGRIVDRMDRAGD
Q96EB6 S27 GPS6|SIGNOR|EPSD|PSP SIRT1 SIR2L1 LALQPGGsPsAAGADREAAssPAGEPLRKRPRRDGPGLERs
Q96EB6 S47 GPS6|SIGNOR|EPSD|PSP SIRT1 SIR2L1 sPAGEPLRKRPRRDGPGLERsPGEPGGAAPEREVPAAARGC
Q96EB6 T530 GPS6|SIGNOR|EPSD|PSP SIRT1 SIR2L1 ITEKPPRTQKELAYLSELPPtPLHVsEDsssPERtsPPDss
Q96EK9 S184 Sugiyama KTI12 SBBI81 GSAQADVPKELEREEsGAAEsPALVtPDSEKSAKHGsGAFy
Q96EK9 T189 Sugiyama KTI12 SBBI81 DVPKELEREEsGAAEsPALVtPDSEKSAKHGsGAFysPELL
Q96EN8 S530 Sugiyama MOCOS APSADSQADVIPAVMGRRsLsPQEDALTGSRVWNNSSTVNA
Q96FI4 S207 EPSD|PSP NEIL1 KIPPFEKARSVLEALQQHRPsPELTLSQKIRTKLQNPDLLE
Q96FI4 S306 EPSD|PSP NEIL1 GPLAPKGRKSRKKKSKATQLsPEDRVEDALPPSKAPSRTRR
Q96FI4 S61 EPSD|PSP NEIL1 ESSAYRISASARGKELRLILsPLPGAQPQQEPLALVFRFGM
Q96GM8 S425 Sugiyama TOE1 MGIKAARPEIADRATsEVPGsQAsPNPVPGDGLHRAGFDAF
Q96GM8 S428 Sugiyama TOE1 KAARPEIADRATsEVPGsQAsPNPVPGDGLHRAGFDAFMTG
Q96HN2 S107 Sugiyama AHCYL2 KIAA0828 KRSDPHHQHQRHRDGGEALVsPDGTVTEAPRTVKKQIQFAD
Q96I25 S222 PSP RBM17 SPF45 sQsSKAAIPPPVyEEQDRPRsPtGPsNsFLANMGGTVAHKI
Q96I25 T71 PSP RBM17 SPF45 LAPVIDLKRGGssDDRQIVDtPPHVAAGLKDPVPSGFSAGE
Q96J02 S240 SIGNOR ITCH GsDDPEDAGAGENRRVsGNNsPsLSNGGFKPSRPPRPsRPP
Q96J02 S273 SIGNOR ITCH PPRPsRPPPPtPRRPASVNGsPSATSESDGSSTGSLPPTNT
Q96J02 T263 SIGNOR ITCH LSNGGFKPSRPPRPsRPPPPtPRRPASVNGsPSATSESDGS
Q96K76 S910 Sugiyama USP47 DGDNGDssKstEtsDFENIEsPLNERDsSAsVDNRELEQHI
Q96LC9 S74 iPTMNet|EPSD|PSP BMF HCCGPGLRPTSQEDKATQTLsPAsPsQGVMLPCGVTEEPQR
Q96LC9 S77 iPTMNet BMF GPGLRPTSQEDKATQTLsPAsPsQGVMLPCGVTEEPQRLFY
Q96MH2 S29 Sugiyama HEXIM2 L3 ACNAEsPVALEEAKtsGAPGsPQtPPERHDsGGsLPLtPRM
Q96MH2 S39 Sugiyama HEXIM2 L3 EEAKtsGAPGsPQtPPERHDsGGsLPLtPRMEsHsEDEDLA
Q96MH2 S76 Sugiyama HEXIM2 L3 EDLAGAVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPS
Q96MH2 T32 Sugiyama HEXIM2 L3 AEsPVALEEAKtsGAPGsPQtPPERHDsGGsLPLtPRMEsH
Q96N67 S241 Sugiyama DOCK7 KIAA1771 RQNDDQRKSNRHKELFALHPsPDEEEPIERLSVPDIPKEHF
Q96P20 S198 SIGNOR|EPSD|PSP NLRP3 C1orf7 CIAS1 NALP3 PYPAF1 RSQQEREQELLAIGKTKTCEsPVSPIKMELLFDPDDEHSEP
Q96QK1 S783 Sugiyama VPS35 MEM3 TCCCTA00141 tEQINKHFHNtLEHLRLRREsPEsEGPIyEGLIL_______
Q96S44 T8 Sugiyama TP53RK C20orf64 PRPK _____________MAAARAttPADGEEPAPEAEALAAARER
Q96S55 T116 Sugiyama WRNIP1 WHIP GEEGDDGGETESREsyDAPPtPsGARLIPDFPVARsssPGR
Q96SB4 S311 Sugiyama SRPK1 EMEKESGPGQKRPNKQEEsEsPVERPLKENPPNKMtQEKLE
Q96ST3 T161 Sugiyama SIN3A PQVYNDFLDIMKEFKSQsIDtPGVISRVSQLFKGHPDLIMG
Q99460 S315 Sugiyama PSMD1 DsMEtEEKTSsAFVGKtPEAsPEPKDQTLKMIKILSGEMAI
Q99460 T311 Sugiyama PSMD1 EKDsDsMEtEEKTSsAFVGKtPEAsPEPKDQTLKMIKILSG
Q99543 T539 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 KKAFDKFKKEHGVVPQADNAtPsERFEGPytDFTPWTtEEQ
Q99607 S641 EPSD|PSP ELF4 ELFR MEF SGSLLMAEPSVTTSGSLLTRsPtPAPFsPFNPTSLIKMEPH
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99666 T1474 Sugiyama RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6 DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
Q9BPU6 T509 Sugiyama DPYSL5 CRMP5 ULIP6 RTPYLGDVAVVVHPGKKEMGtPLADtPtRPVTRHGGMRDLH
Q9BPU6 T514 Sugiyama DPYSL5 CRMP5 ULIP6 GDVAVVVHPGKKEMGtPLADtPtRPVTRHGGMRDLHEssFs
Q9BQ52 S618 Sugiyama ELAC2 HPC2 VLHHISMIPAKCLQEGAEIssPAVERLISSLLRTCDLEEFQ
Q9BQE3 S439 Sugiyama TUBA1C TUBA6 SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BQE3 S48 Sugiyama TUBA1C TUBA6 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3 T51 Sugiyama TUBA1C TUBA6 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T80 Sugiyama TUBA1C TUBA6 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQG0 S11 Sugiyama MYBBP1A P160 __________MEsRDPAQPMsPGEAtQsGARPADRYGLLKH
Q9BQG0 S1163 Sugiyama MYBBP1A P160 GVQRPKLEKKDAKEIPsAtQsPIsKKRKKKGFLPETKKRKK
Q9BTC0 S1471 Sugiyama DIDO1 C20orf158 DATF1 KIAA0333 DVRRNsVERPAEPVAGAAtPsLVEQQKMLEELNKQIEEQKR
Q9BTC0 T1469 Sugiyama DIDO1 C20orf158 DATF1 KIAA0333 CADVRRNsVERPAEPVAGAAtPsLVEQQKMLEELNKQIEEQ
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BVA1 T72 Sugiyama TUBB2B NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q9BX68 T47 Sugiyama HINT2 QVRGAAGVTDGNEVAKAQQAtPGGAAPtIFsRILDKsLPAD
Q9BXJ9 T652 Sugiyama NAA15 GA19 NARG1 NATH TBDN100 DEEIGGPKEELIPEKLAKVEtPLEEAIKFLTPLKNLVKNKI
Q9BXP5 S493 Sugiyama SRRT ARS2 ASR2 VNIKEICWNLQNIRLRECELsPGVNRDLTRRVRNINGITQH
Q9BY44 S503 Sugiyama EIF2A CDA02 MSTP004 MSTP089 TALKNQRKHEAKKAAKQEARsDKsPDLAPtPAPQstPRNtV
Q9BY44 T512 Sugiyama EIF2A CDA02 MSTP004 MSTP089 EAKKAAKQEARsDKsPDLAPtPAPQstPRNtVsQsIsGDPE
Q9BYG3 T234 Sugiyama NIFK MKI67IP NOPP34 KKKVsGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELND
Q9BYG3 T238 Sugiyama NIFK MKI67IP NOPP34 sGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELNDDDKD
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BYX7 T89 Sugiyama POTEKP ACTBL3 FKSG30 YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BYX7 Y362 Sugiyama POTEKP ACTBL3 FKSG30 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q9BYX7 Y91 Sugiyama POTEKP ACTBL3 FKSG30 MEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAPLN
Q9BZH6 S1216 Sugiyama WDR11 BRWD2 KIAA1351 WDR15 AVLFASKAGAAGKDLLNELEsPKEEPIEE____________
Q9C0C2 S1103 Sugiyama TNKS1BP1 KIAA1741 TAB182 KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ
Q9C0C2 S1297 Sugiyama TNKS1BP1 KIAA1741 TAB182 GQADWtPDLGLRNMAPGAVCsPGEsKELGVGQMDWGNNLGL
Q9C0C2 S435 Sugiyama TNKS1BP1 KIAA1741 TAB182 DAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAALPQGQG
Q9C0C2 S494 Sugiyama TNKS1BP1 KIAA1741 TAB182 QSFEWTFPTRPSGLGVWRLDsPPPsPItEAsEAAEAAEAGN
Q9C0C2 S498 Sugiyama TNKS1BP1 KIAA1741 TAB182 WTFPTRPSGLGVWRLDsPPPsPItEAsEAAEAAEAGNLAVS
Q9C0C2 S601 Sugiyama TNKS1BP1 KIAA1741 TAB182 LPLQQAEERyEsQEPLAGQEsPLPLATREAALPILEPVLGQ
Q9C0C2 S672 Sugiyama TNKS1BP1 KIAA1741 TAB182 TLARAETtQARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsP
Q9C0C2 S712 Sugiyama TNKS1BP1 KIAA1741 TAB182 PPPsGGGARRGAGAELKDtQsPstCsEGLLGWsQKDLQSEF
Q9C0C7 S639 Sugiyama AMBRA1 DCAF3 KIAA1736 LERTEGQTPsSsRLELsssAsPQEERTVGVAFNQETGHWER
Q9C0E2 S521 Sugiyama XPO4 KIAA1721 EERVTRLHGQLQRHQQQLLAsPGssTVDNKMLDDLYEDIHW
Q9H078 S668 Sugiyama CLPB SKD3 TLRITVEDSDKQLLKsPELPsPQAEKRLPKLRLEIIDKDSK
Q9H0B6 S445 Sugiyama KLC2 RRDsAPyGEyGsWYKACKVDsPtVNTTLRSLGALYRRQGKL
Q9H0D6 T433 Sugiyama XRN2 SFRRRQKEKRKRMKRDQPAFtPsGILtPHALGsRNsPGsQV
Q9H0D6 T439 Sugiyama XRN2 KEKRKRMKRDQPAFtPsGILtPHALGsRNsPGsQVAsNPRQ
Q9H1A4 S313 Sugiyama ANAPC1 TSG24 QNVAtsssLTAHLRsLsKGDsPVtsPFQNysSIHSQSRSTs
Q9H1A4 S317 Sugiyama ANAPC1 TSG24 tsssLTAHLRsLsKGDsPVtsPFQNysSIHSQSRSTssPsL
Q9H1A4 T316 Sugiyama ANAPC1 TSG24 AtsssLTAHLRsLsKGDsPVtsPFQNysSIHSQSRSTssPs
Q9H211 S391 SIGNOR|PSP CDT1 IsPRMEKALsQLALRsAAPssPGsPRPALPAtPPAtPPAAs
Q9H211 S411 PSP CDT1 sPGsPRPALPAtPPAtPPAAsPSALKGVSQDLLERIRAKEA
Q9H211 S491 SIGNOR|PSP CDT1 PALSMEVACARMVGSCCTIMsPGEMEKHLLLLSELLPDWLS
Q9H211 T29 GPS6|EPSD|PSP CDT1 FFARRRPGPPRIAPPKLACRtPsPARPALRAPASATSGSRK
Q9H211 T402 PSP CDT1 LALRsAAPssPGsPRPALPAtPPAtPPAAsPSALKGVSQDL
Q9H211 T406 PSP CDT1 sAAPssPGsPRPALPAtPPAtPPAAsPSALKGVSQDLLERI
Q9H2B2 S135 SIGNOR|EPSD|PSP SYT4 KIAA1342 PSDLENATPKLFLEGEKESVsPESLKSSTSLTSEEKQEKLG
Q9H2U2 S317 Sugiyama PPA2 HSPC124 DSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK___
Q9H3D4 S51 PSP TP63 KET P63 P73H P73L TP73L WKESYYRSTMSQsTQtNEFLsPEVFQHIWDFLEQPICsVQP
Q9H4A5 S112 Sugiyama GOLPH3L GPP34R EPPTMRKKRLLDRKVLLKsDsPTGDVLLDETLKHIKATEPT
Q9HAP6 S115 Sugiyama LIN7B MALS2 VELI2 UNQ3116/PRO10200 ELPKTDEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLK
Q9HC38 T242 Sugiyama GLOD4 C17orf25 CGI-150 My027 PQKELPDLEDLMKRENQKILtPLVsLDtPGKATVQVVILAD
Q9HC38 T249 Sugiyama GLOD4 C17orf25 CGI-150 My027 LEDLMKRENQKILtPLVsLDtPGKATVQVVILADPDGHEIC
Q9HDC5 S413 Sugiyama JPH1 JP1 QAALAARQECDIARAVARELsPDFyQPGPDyVKQRFQEGVD
Q9HDC9 T190 Sugiyama APMAP C20orf3 UNQ1869/PRO4305 KGLFEVNPWKREVKLLLSsEtPIEGKNMSFVNDLTVTQDGR
Q9NPI6 S315 EPSD|PSP DCP1A SMIF TPASITQSNEKHAPtYtIPLsPVLsPtLPAEAPTAQVPPsL
Q9NPI6 T531 Sugiyama DCP1A SMIF VTRSSDLERKAssPsPLtIGtPEsQRKPSIILSKsQLQDTL
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQR4 S133 Sugiyama NIT2 CUA002 IHLFDIDVPGKITFQESKTLsPGDsFSTFDTPyCRVGLGIC
Q9NR28 S6 EPSD|PSP DIABLO SMAC _______________MAALKsWLsRSVTSFFRYRQCLCVPV
Q9NR28 S9 EPSD|PSP DIABLO SMAC ____________MAALKsWLsRSVTSFFRYRQCLCVPVVAN
Q9NRA8 S301 SIGNOR|EPSD|PSP EIF4ENIF1 LAQEPAADQEVPRDAVLPEQsPGDFDFNEFFNLDKVPCLAS
Q9NRA8 S374 SIGNOR|EPSD|PSP EIF4ENIF1 LGstPHEELERLAGLEQAILsPGQNsGNyFAPIPLEDHAEN
Q9NRA8 S513 SIGNOR|EPSD|PSP EIF4ENIF1 ASGTLPsQPKVSRNLESHLMsPAEIPGQPVPKNILQELLGQ
Q9NRA8 S587 SIGNOR|EPSD|PSP EIF4ENIF1 LsQVFQTRAAsADYLRPRIPsPIGFtPGPQQLLGDPFQGMR
Q9NRA8 S693 SIGNOR|EPSD|PSP EIF4ENIF1 PVHRGNsssPAPAAsItsMLsPSFtPTSVIRKMYESKEKSK
Q9NRA8 S752 SIGNOR|EPSD|PSP EIF4ENIF1 KASEENLLSsssVPsADRDssPttNsKLSALQRSsCstPLS
Q9NSK0 S460 Sugiyama KLC4 KNSL8 HEGGtPYAEYGGWYKACKVssPTVNTTLRNLGALyRRQGKL
Q9NTJ3 S22 Sugiyama SMC4 CAPC SMC4L1 PRKGTQPSTARRREEGPPPPsPDGAssDAEPEPPsGRtEsP
Q9NUP9 S115 Sugiyama LIN7C MALS3 VELI3 ELPKTEEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLK
Q9NUQ3 S97 Sugiyama TXLNG CXorf15 ELRG LSR5 KHSLEEDEGsDFItENRNLVsPAyCtQEsREEIPGGEARTD
Q9NWS0 T195 Sugiyama PIH1D1 NOP17 sQQNIRSEQRPRIQELGDLytPAPGRAESGPEKPHLNLWLE
Q9NYD6 S189 Sugiyama HOXC10 HOX3I DFEAPFEQRASLNPRAEHLEsPQLGGKVSFPEtPKsDsQtP
Q9NYF3 S254 Sugiyama FAM53C C5orf6 sPsLGPQASRFLPSARssPAssPELPWRPRGLRNLPRsRsQ
Q9NYF8 S290 Sugiyama BCLAF1 BTF KIAA0164 ERsGsGsVGNGssRysPsQNsPIHHIPsRRsPAKtIAPQNA
Q9NZ72 S60 PSP STMN3 SCLIP MEVKQLDKRAsGQsFEVILKsPSDLsPEsPMLssPPKKKDt
Q9NZB2 T991 Sugiyama FAM120A C9orf10 KIAA0183 OSSA PLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKNQ
Q9NZN8 S242 Sugiyama CNOT2 CDC36 NOT2 HSPC131 MSTP046 VTGLDLSDFPALADRNRREGsGNPtPLINPLAGRAPYVGMV
Q9NZN8 T246 Sugiyama CNOT2 CDC36 NOT2 HSPC131 MSTP046 DLSDFPALADRNRREGsGNPtPLINPLAGRAPYVGMVTKPA
Q9NZT2 S315 Sugiyama OGFR FKPSSLPHPLEGSRKVEEEGsPGDPDHEAstQGRTCGPEHS
Q9NZT2 S378 Sugiyama OGFR LERsQGDEAGGHGEDRPEPLsPKEsKKRKLELSRREQPPTE
Q9P2E9 S615 Sugiyama RRBP1 KIAA1398 NQGKKTEsAsVQGRNTDVAQsPEAPKQEAPAKKKSGSKKKG
Q9UEY8 S673 Sugiyama ADD3 ADDL ttIENIEITIKsPEKIEEVLsPEGsPsKsPsKKKKKFRTPs
Q9UGP4 S272 PSP LIMD1 GGRssEKPtGLWstASSQRVsPGLPsPNLENGAPAVGPVQP
Q9UGP4 S277 PSP LIMD1 EKPtGLWstASSQRVsPGLPsPNLENGAPAVGPVQPRtPsV
Q9UGP4 S421 PSP LIMD1 CKEGPLGWSSDGsLGsVLLDsPssPRVRLPCQPLVPGPELR
Q9UGP4 S424 PSP LIMD1 GPLGWSSDGsLGsVLLDsPssPRVRLPCQPLVPGPELRPSA
Q9UGV2 S341 Sugiyama NDRG3 MTRLARsRtHstsssLGsGEsPFsRsVtsNQsDGtQESCEs
Q9UGV2 S361 Sugiyama NDRG3 sPFsRsVtsNQsDGtQESCEsPDVLDRHQTMEVsC______
Q9UHB6 S490 Sugiyama LIMA1 EPLIN SREBP3 PP624 ENEEILERPAQLANAREtPHsPGVEDAPIAKVGVLAAsMEA
Q9UI10 S130 Sugiyama EIF2B4 EIF2BD AERALKQARKGEQGGPPPKAsPstAGEtPsGVKRLPEYPQV
Q9UI10 S132 Sugiyama EIF2B4 EIF2BD RALKQARKGEQGGPPPKAsPstAGEtPsGVKRLPEYPQVDD
Q9UI10 T137 Sugiyama EIF2B4 EIF2BD ARKGEQGGPPPKAsPstAGEtPsGVKRLPEYPQVDDLLLRR
Q9UI10 T86 Sugiyama EIF2B4 EIF2BD AAQCQVGPTRELPESGIQLGtPREKVPAGRSKAELRAERRA
Q9UKG1 T399 Sugiyama APPL1 APPL DIP13A KIAA1428 LSENPEETAARVNQsALEAVtPsPsFQQRHEsLRPAAGQSR
Q9UKS6 S341 Sugiyama PACSIN3 DEVtLtsIVPTRDGTAPPPQsPGsPGtGQDEEWsDEEsPRK
Q9UKS6 S344 Sugiyama PACSIN3 tLtsIVPTRDGTAPPPQsPGsPGtGQDEEWsDEEsPRKAAT
Q9UKV3 S365 Sugiyama ACIN1 ACINUS KIAA0670 EEARKSHLARQQQEKEMKttsPLEEEEREIKssQGLKEKsK
Q9UKX7 S221 Sugiyama NUP50 NPAP60L PRO1146 HGNsGRNsESEsNKVAAEtQsPsLFGstKLQQEStFLFHGN
Q9UNE7 S23 Sugiyama STUB1 CHIP PP1131 GKEEKEGGARLGAGGGsPEKsPsAQELKEQGNRLFVGRKYP
Q9UNE7 S25 Sugiyama STUB1 CHIP PP1131 EEKEGGARLGAGGGsPEKsPsAQELKEQGNRLFVGRKYPEA
Q9UNX3 S32 Sugiyama RPL26L1 RPL26P1 sKNRKRHFNAPSHVRRKIMssPLSKELRQKYNVRSMPIRKD
Q9UPQ0 S973 Sugiyama LIMCH1 KIAA1102 SEDVKPKTLPLDKsINHQIEsPsERRKKSPREHFQAGPFsP
Q9UPT6 T265 SIGNOR|iPTMNet MAPK8IP3 JIP3 KIAA1066 SSYQCPQDEMSESGQSSAAAtPSTTGTKsNtPtssVPSAAV
Q9UPT6 T275 SIGNOR|iPTMNet MAPK8IP3 JIP3 KIAA1066 SESGQSSAAAtPSTTGTKsNtPtssVPSAAVtPLNESLQPL
Q9UPT6 T286 SIGNOR|iPTMNet MAPK8IP3 JIP3 KIAA1066 PSTTGTKsNtPtssVPSAAVtPLNESLQPLGDYGVGSKNSK
Q9UQ35 S1103 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sPsLQSKSQTsPKGGRsRsssPVtELAsRsPIRQDRGEFsA
Q9UQ35 S1112 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 TsPKGGRsRsssPVtELAsRsPIRQDRGEFsAsPMLKsGMs
Q9UQ35 S1320 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sMASSWGGPHFsPEHKELsNsPLRENsFGsPLEFRNsGPLG
Q9UQ35 S1329 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 HFsPEHKELsNsPLRENsFGsPLEFRNsGPLGTEMNtGFss
Q9UQ35 S1387 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 PsLDMKEQstRssGHsssELsPDAVEKAGMssNQsIssPVL
Q9UQ35 S1404 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sELsPDAVEKAGMssNQsIssPVLDAVPRtPsRERsssAss
Q9UQ35 S2272 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 tAVNLADsRtPAAAAAMNLAsPRtAVAPsAVNLADPRtPtA
Q9UQ35 S857 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sssPHPKVKsGtPPRQGsItsPQANEQsVtPQRRsCFEssP
Q9UQ35 S994 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sPDtKVKPEtPPRQsHsGsIsPyPKVKAQtPPGPsLsGsKs
Q9UQ35 T1413 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 KAGMssNQsIssPVLDAVPRtPsRERsssAssPEMKDGLPR
Q9UQ35 T384 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 PAPtPLLAERHGGsPQPLAttPLsQEPVNPPsEAsPtRDRs
Q9UQ80 T386 Sugiyama PA2G4 EBP1 tQKKKKKKAsKtAENAtsGEtLEENEAGD____________
Q9UQF2 S15 SIGNOR|ELM|iPTMNet MAPK8IP1 IB1 JIP1 PRKM8IP ______MAERESGGLGGGAAsPPAASPFLGLHIAsPPNFRL
Q9UQF2 S197 SIGNOR|ELM|iPTMNet MAPK8IP1 IB1 JIP1 PRKM8IP LNNNSLGKKHSWQDRVSRSSsPLKTGEQtPPHEHICLSDEL
Q9UQF2 S29 SIGNOR|ELM|iPTMNet MAPK8IP1 IB1 JIP1 PRKM8IP LGGGAAsPPAASPFLGLHIAsPPNFRLTHDISLEEFEDEDL
Q9UQF2 S341 ELM|iPTMNet|EPSD MAPK8IP1 IB1 JIP1 PRKM8IP TAGRPHPSISEEEEGFDCLSsPERAEPPGGGWRGSLGEPPP
Q9UQF2 S421 SIGNOR|ELM|iPTMNet MAPK8IP1 IB1 JIP1 PRKM8IP GDYSDESDSATVYDNCASVSsPYESAIGEEYEEAPRPQPPA
Q9UQF2 T103 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP MAPK8IP1 IB1 JIP1 PRKM8IP AGSRLQAEMLQMDLIDATGDtPGAEDDEEDDDEERAARRPG
Q9UQF2 T205 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP MAPK8IP1 IB1 JIP1 PRKM8IP KHSWQDRVSRSSsPLKTGEQtPPHEHICLSDELPPQSGPAP
Q9UQF2 T284 ELM|iPTMNet MAPK8IP1 IB1 JIP1 PRKM8IP RDRIHYQADVRLEATEEIYLtPVQRPPDAAEPTSAFLPPTE
Q9Y266 T303 Sugiyama NUDC tRsMVEKMMYDQRQKsMGLPtsDEQKKQEILKKFMDQHPEM
Q9Y2T7 S137 Sugiyama YBX2 CSDA3 MSY2 EDVFVHQtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEA
Q9Y2V2 S41 Sugiyama CARHSP1 LDtPRsRERsPsPLRGNVVPsPLPtRRtRtFsAtVRASQGP
Q9Y2W2 S237 Sugiyama WBP11 NPWBP SIPP1 SNP70 RKVGFALDLPPRRRDEDMLysPELAQRGHDDDVSSTSEDDG
Q9Y2X7 S362 Sugiyama GIT1 TLIIDILSEAKRRQQGKsLssPtDNLELsLRSQSDLDDQHD
Q9Y4E8 S229 Sugiyama USP15 KIAA0529 LVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPssLsNN
Q9Y4E8 T226 Sugiyama USP15 KIAA0529 GQVLVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPssL
Q9Y5U2 S143 Sugiyama TSSC4 KRPLAPsGRsPVEGLGRAHRsPAsPRVPPVPDYVAHPERWT
Q9Y5U2 S146 Sugiyama TSSC4 LAPsGRsPVEGLGRAHRsPAsPRVPPVPDYVAHPERWTKYS
Q9Y6G9 S516 Sugiyama DYNC1LI1 DNCLI1 HAELDRITRKPVtVsPttPtsPtEGEAs_____________
Q9Y6G9 T515 Sugiyama DYNC1LI1 DNCLI1 VHAELDRITRKPVtVsPttPtsPtEGEAs____________
Q9Y6Q9 S505 EPSD|PSP NCOA3 AIB1 BHLHE42 RAC3 TRAM1 RNRGSPKIASHQFSPVAGVHsPMAsSGNTGNHSFSSSSLSA
Q9Y6Q9 S543 EPSD|PSP NCOA3 AIB1 BHLHE42 RAC3 TRAM1 LSALQAISEGVGTSLLSTLSsPGPKLDNsPNMNITQPSKVs
Q9Y6Q9 S860 EPSD|PSP NCOA3 AIB1 BHLHE42 RAC3 TRAM1 KSSQSVQSIRPPYNRAVsLDsPVsVGssPPVKNISAFPMLP
Q9Y6Q9 S867 EPSD|PSP NCOA3 AIB1 BHLHE42 RAC3 TRAM1 SIRPPYNRAVsLDsPVsVGssPPVKNISAFPMLPKQPMLGG
Q9Y6Q9 T24 EPSD|PSP NCOA3 AIB1 BHLHE42 RAC3 TRAM1 LGENLDPLAsDSRKRKLPCDtPGQGLtCsGEKRRREQESKY
Site Promiscuity

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Chromatin organization R-HSA-4839726 1.606060e-08 7.794 0 0
Chromatin modifying enzymes R-HSA-3247509 9.818043e-08 7.008 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.187807e-06 5.925 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 3.832390e-06 5.417 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 4.806870e-06 5.318 0 0
Signal Transduction R-HSA-162582 5.153433e-06 5.288 1 0
Transcriptional regulation by RUNX1 R-HSA-8878171 7.774097e-06 5.109 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.071194e-05 4.970 0 0
Gene expression (Transcription) R-HSA-74160 1.178928e-05 4.929 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.266034e-05 4.898 0 0
Cell Cycle R-HSA-1640170 1.835719e-05 4.736 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 1.987687e-05 4.702 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 2.466649e-05 4.608 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 2.635396e-05 4.579 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.595378e-05 4.586 0 0
Cell Cycle, Mitotic R-HSA-69278 2.222186e-05 4.653 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.648567e-05 4.438 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 4.494501e-05 4.347 0 0
ESR-mediated signaling R-HSA-8939211 4.355102e-05 4.361 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 5.812860e-05 4.236 1 0
Mitotic Prometaphase R-HSA-68877 6.331863e-05 4.198 0 0
Estrogen-dependent gene expression R-HSA-9018519 6.875051e-05 4.163 0 0
Regulation of TP53 Activity R-HSA-5633007 7.745937e-05 4.111 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 8.666859e-05 4.062 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.039350e-04 3.983 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.315899e-04 3.881 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.606731e-04 3.794 0 0
RNA Polymerase II Transcription R-HSA-73857 1.754921e-04 3.756 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.948629e-04 3.710 0 0
Signaling by NTRKs R-HSA-166520 2.061830e-04 3.686 0 0
Signaling by ERBB2 R-HSA-1227986 2.780785e-04 3.556 0 0
Separation of Sister Chromatids R-HSA-2467813 2.732715e-04 3.563 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 2.948338e-04 3.530 0 0
Epigenetic regulation of gene expression R-HSA-212165 3.019767e-04 3.520 0 0
Generic Transcription Pathway R-HSA-212436 3.222684e-04 3.492 0 0
M Phase R-HSA-68886 3.571549e-04 3.447 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 4.873314e-04 3.312 0 0
Amplification of signal from the kinetochores R-HSA-141424 4.873314e-04 3.312 0 0
Post NMDA receptor activation events R-HSA-438064 5.965764e-04 3.224 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 6.009391e-04 3.221 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 5.873205e-04 3.231 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 6.158404e-04 3.211 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 6.637921e-04 3.178 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.585667e-04 3.181 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 7.251542e-04 3.140 0 0
Recycling pathway of L1 R-HSA-437239 6.979832e-04 3.156 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 7.320720e-04 3.135 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 7.675693e-04 3.115 0 0
Mitotic Spindle Checkpoint R-HSA-69618 8.315668e-04 3.080 0 0
Cellular Senescence R-HSA-2559583 8.736924e-04 3.059 1 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 8.440137e-04 3.074 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 8.906984e-04 3.050 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 1.244250e-03 2.905 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 1.108871e-03 2.955 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.102579e-03 2.958 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.102579e-03 2.958 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 1.291697e-03 2.889 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.124666e-03 2.949 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 1.102579e-03 2.958 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.054219e-03 2.977 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.243238e-03 2.905 0 0
CREB phosphorylation R-HSA-199920 1.321993e-03 2.879 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 1.128302e-03 2.948 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.387054e-03 2.858 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.458179e-03 2.836 0 0
Signaling by WNT R-HSA-195721 1.416451e-03 2.849 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.476989e-03 2.831 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.588556e-03 2.799 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.588556e-03 2.799 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.588556e-03 2.799 0 0
Repression of WNT target genes R-HSA-4641265 1.588556e-03 2.799 0 0
Signaling by LTK R-HSA-9842663 1.588556e-03 2.799 0 0
Mitotic Anaphase R-HSA-68882 1.585044e-03 2.800 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.673468e-03 2.776 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 1.715517e-03 2.766 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.747001e-03 2.758 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.910827e-03 2.719 0 0
RET signaling R-HSA-8853659 2.017794e-03 2.695 0 0
Nuclear Envelope Breakdown R-HSA-2980766 2.363787e-03 2.626 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 2.670699e-03 2.573 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 2.721745e-03 2.565 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 2.971641e-03 2.527 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 3.032279e-03 2.518 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.088481e-03 2.510 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 3.310100e-03 2.480 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.446961e-03 2.463 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.446961e-03 2.463 0 0
Viral Messenger RNA Synthesis R-HSA-168325 3.588980e-03 2.445 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 3.892206e-03 2.410 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 3.903264e-03 2.409 0 0
L1CAM interactions R-HSA-373760 3.697038e-03 2.432 0 0
FLT3 Signaling R-HSA-9607240 3.903264e-03 2.409 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 4.366506e-03 2.360 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 4.366506e-03 2.360 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 4.568986e-03 2.340 0 0
Signal attenuation R-HSA-74749 4.900021e-03 2.310 0 0
MTOR signalling R-HSA-165159 4.955751e-03 2.305 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 4.900021e-03 2.310 0 0
Developmental Biology R-HSA-1266738 4.698621e-03 2.328 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 5.024323e-03 2.299 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 5.223788e-03 2.282 0 0
Axon guidance R-HSA-422475 5.286772e-03 2.277 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 5.911291e-03 2.228 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 5.911291e-03 2.228 0 0
AURKA Activation by TPX2 R-HSA-8854518 5.775105e-03 2.238 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 6.082576e-03 2.216 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 6.082576e-03 2.216 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 5.803428e-03 2.236 0 0
HDMs demethylate histones R-HSA-3214842 5.911291e-03 2.228 0 0
G2/M Transition R-HSA-69275 5.786747e-03 2.238 0 0
Nuclear import of Rev protein R-HSA-180746 5.946596e-03 2.226 0 0
Nervous system development R-HSA-9675108 6.128755e-03 2.213 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 6.130154e-03 2.213 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 6.212814e-03 2.207 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 6.292716e-03 2.201 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 6.741559e-03 2.171 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 7.288406e-03 2.137 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 7.288406e-03 2.137 0 0
Regulation of TP53 Degradation R-HSA-6804757 7.612836e-03 2.118 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 7.992970e-03 2.097 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 8.554672e-03 2.068 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 8.554672e-03 2.068 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 8.651580e-03 2.063 0 0
snRNP Assembly R-HSA-191859 8.895932e-03 2.051 0 0
Metabolism of non-coding RNA R-HSA-194441 8.895932e-03 2.051 0 0
PIP3 activates AKT signaling R-HSA-1257604 8.159607e-03 2.088 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 8.564584e-03 2.067 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 9.974149e-03 2.001 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 1.018150e-02 1.992 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.033527e-02 1.986 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 9.855008e-03 2.006 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 9.304451e-03 2.031 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 1.033527e-02 1.986 1 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 9.974149e-03 2.001 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 9.600942e-03 2.018 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 9.236350e-03 2.034 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.040508e-02 1.983 0 0
Gap junction trafficking and regulation R-HSA-157858 1.040671e-02 1.983 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.043417e-02 1.982 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.043417e-02 1.982 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.043417e-02 1.982 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.188716e-02 1.925 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.188716e-02 1.925 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 1.173070e-02 1.931 0 0
Cell Cycle Checkpoints R-HSA-69620 1.120441e-02 1.951 0 0
Mitotic Prophase R-HSA-68875 1.110392e-02 1.955 0 0
Aggrephagy R-HSA-9646399 1.194386e-02 1.923 0 0
Signaling by FGFR in disease R-HSA-1226099 1.128284e-02 1.948 0 0
tRNA processing in the nucleus R-HSA-6784531 1.155868e-02 1.937 0 0
Activation of BH3-only proteins R-HSA-114452 1.173232e-02 1.931 1 0
Signaling by ALK R-HSA-201556 1.072601e-02 1.970 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 1.194386e-02 1.923 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.194386e-02 1.923 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.072601e-02 1.970 0 0
Centrosome maturation R-HSA-380287 1.218277e-02 1.914 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.221565e-02 1.913 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.221565e-02 1.913 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.221565e-02 1.913 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 1.221565e-02 1.913 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.256652e-02 1.901 0 0
Signaling by PTK6 R-HSA-8848021 1.256652e-02 1.901 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 1.325846e-02 1.878 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.325846e-02 1.878 0 0
IGF1R signaling cascade R-HSA-2428924 1.363832e-02 1.865 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.377707e-02 1.861 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.467375e-02 1.833 0 0
Regulation of KIT signaling R-HSA-1433559 1.475605e-02 1.831 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 1.477634e-02 1.830 0 0
Diseases of mitotic cell cycle R-HSA-9675126 1.491587e-02 1.826 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.491587e-02 1.826 0 0
Disinhibition of SNARE formation R-HSA-114516 1.549904e-02 1.810 0 0
SOS-mediated signalling R-HSA-112412 1.549904e-02 1.810 0 0
HDACs deacetylate histones R-HSA-3214815 1.784985e-02 1.748 0 0
G alpha (z) signalling events R-HSA-418597 1.784985e-02 1.748 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.593216e-02 1.798 1 1
Signaling by FGFR2 R-HSA-5654738 1.751493e-02 1.757 0 0
Signaling by FGFR4 R-HSA-5654743 1.782155e-02 1.749 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.760712e-02 1.754 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 1.549904e-02 1.810 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.751493e-02 1.757 0 0
HCMV Early Events R-HSA-9609690 1.800247e-02 1.745 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.826902e-02 1.738 0 0
Regulation of TP53 Expression R-HSA-6804754 1.848810e-02 1.733 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.877102e-02 1.727 0 0
Signaling by EGFR R-HSA-177929 1.938686e-02 1.712 0 0
NRAGE signals death through JNK R-HSA-193648 1.938686e-02 1.712 1 1
Gap junction trafficking R-HSA-190828 1.956139e-02 1.709 0 0
RSK activation R-HSA-444257 1.987180e-02 1.702 0 0
Gap junction assembly R-HSA-190861 2.074379e-02 1.683 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.077890e-02 1.682 0 0
Signaling by FGFR3 R-HSA-5654741 2.141653e-02 1.669 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.141653e-02 1.669 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 2.153756e-02 1.667 0 0
Membrane Trafficking R-HSA-199991 2.161666e-02 1.665 0 0
Metabolism of RNA R-HSA-8953854 2.207277e-02 1.656 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 2.427973e-02 1.615 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 2.625056e-02 1.581 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.625056e-02 1.581 0 0
Cellular response to heat stress R-HSA-3371556 2.516653e-02 1.599 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 2.763342e-02 1.559 0 0
TGFBR3 expression R-HSA-9839394 2.333086e-02 1.632 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 2.439807e-02 1.613 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.625056e-02 1.581 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 2.625056e-02 1.581 0 0
Cellular responses to stress R-HSA-2262752 2.694688e-02 1.569 1 0
Regulation of PTEN gene transcription R-HSA-8943724 2.648138e-02 1.577 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 2.478184e-02 1.606 0 0
Calmodulin induced events R-HSA-111933 2.538657e-02 1.595 0 0
CaM pathway R-HSA-111997 2.538657e-02 1.595 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 2.478184e-02 1.606 0 0
Apoptotic execution phase R-HSA-75153 2.339031e-02 1.631 0 0
FLT3 signaling in disease R-HSA-9682385 2.538657e-02 1.595 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 2.339031e-02 1.631 0 0
NGF-stimulated transcription R-HSA-9031628 2.770634e-02 1.557 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 2.816426e-02 1.550 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 2.939365e-02 1.532 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 2.939365e-02 1.532 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 2.939365e-02 1.532 0 0
FOXO-mediated transcription R-HSA-9614085 2.973442e-02 1.527 0 0
HATs acetylate histones R-HSA-3214847 2.973442e-02 1.527 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.005447e-02 1.522 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 3.044645e-02 1.516 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 3.063086e-02 1.514 0 0
Selective autophagy R-HSA-9663891 3.116331e-02 1.506 0 0
Signaling by NOTCH R-HSA-157118 3.139428e-02 1.503 0 0
Signaling by VEGF R-HSA-194138 3.224462e-02 1.492 0 0
Ephrin signaling R-HSA-3928664 3.229335e-02 1.491 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 3.229335e-02 1.491 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 3.229335e-02 1.491 0 0
Polo-like kinase mediated events R-HSA-156711 3.229335e-02 1.491 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 3.276442e-02 1.485 0 0
Formation of the Early Elongation Complex R-HSA-113418 3.276442e-02 1.485 0 0
HIV elongation arrest and recovery R-HSA-167287 3.276442e-02 1.485 0 0
Pausing and recovery of HIV elongation R-HSA-167290 3.276442e-02 1.485 0 0
Regulation of gap junction activity R-HSA-191650 3.890242e-02 1.410 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 3.890242e-02 1.410 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 3.890242e-02 1.410 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 3.890242e-02 1.410 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 3.664247e-02 1.436 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.636647e-02 1.439 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 4.020277e-02 1.396 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 4.020277e-02 1.396 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 4.020277e-02 1.396 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 3.356843e-02 1.474 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 3.636647e-02 1.439 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 4.020277e-02 1.396 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 3.630974e-02 1.440 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 4.168131e-02 1.380 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 4.020277e-02 1.396 0 0
Late Phase of HIV Life Cycle R-HSA-162599 4.092130e-02 1.388 0 0
Signaling by MET R-HSA-6806834 4.122917e-02 1.385 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 3.890242e-02 1.410 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 3.890242e-02 1.410 0 0
PTEN Regulation R-HSA-6807070 3.438193e-02 1.464 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 3.890242e-02 1.410 0 0
HIV Life Cycle R-HSA-162587 4.088053e-02 1.388 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 3.491158e-02 1.457 0 0
Regulation of gene expression in beta cells R-HSA-210745 3.636647e-02 1.439 0 0
G alpha (12/13) signalling events R-HSA-416482 3.656933e-02 1.437 0 0
Macroautophagy R-HSA-1632852 3.754976e-02 1.425 0 0
PKMTs methylate histone lysines R-HSA-3214841 3.987308e-02 1.399 0 0
ChREBP activates metabolic gene expression R-HSA-163765 3.664247e-02 1.436 0 0
PKR-mediated signaling R-HSA-9833482 4.122917e-02 1.385 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 3.664247e-02 1.436 0 0
Rab regulation of trafficking R-HSA-9007101 4.194701e-02 1.377 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 4.219980e-02 1.375 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 4.328824e-02 1.364 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.343258e-02 1.362 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 4.343258e-02 1.362 0 0
Adipogenesis R-HSA-9843745 4.442165e-02 1.352 0 0
Cilium Assembly R-HSA-5617833 4.646326e-02 1.333 0 0
Ca-dependent events R-HSA-111996 4.688129e-02 1.329 0 0
Signalling to RAS R-HSA-167044 4.689424e-02 1.329 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 4.689424e-02 1.329 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 4.689424e-02 1.329 0 0
ERK/MAPK targets R-HSA-198753 4.689424e-02 1.329 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.696108e-02 1.328 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 4.725765e-02 1.326 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 4.741418e-02 1.324 1 1
Signaling by ALK in cancer R-HSA-9700206 4.741418e-02 1.324 1 0
Gene Silencing by RNA R-HSA-211000 4.741418e-02 1.324 0 0
Apoptosis R-HSA-109581 4.976241e-02 1.303 1 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 5.017991e-02 1.299 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 5.017991e-02 1.299 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 5.017991e-02 1.299 0 0
Signaling by FGFR1 R-HSA-5654736 5.026702e-02 1.299 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 5.026702e-02 1.299 1 0
Cellular responses to stimuli R-HSA-8953897 5.041423e-02 1.297 1 0
TBC/RABGAPs R-HSA-8854214 5.065376e-02 1.295 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 5.080315e-02 1.294 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 5.080315e-02 1.294 0 0
MET activates RAS signaling R-HSA-8851805 5.080315e-02 1.294 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 5.080315e-02 1.294 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 5.121760e-02 1.291 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 5.121760e-02 1.291 0 0
IRS activation R-HSA-74713 5.121760e-02 1.291 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 5.121760e-02 1.291 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 5.121760e-02 1.291 0 0
Organelle biogenesis and maintenance R-HSA-1852241 5.137466e-02 1.289 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 5.873736e-02 1.231 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 6.721567e-02 1.173 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 6.721567e-02 1.173 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 6.459160e-02 1.190 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 6.459160e-02 1.190 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 6.459160e-02 1.190 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 6.305786e-02 1.200 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 6.493529e-02 1.188 0 0
mRNA Splicing - Major Pathway R-HSA-72163 5.346153e-02 1.272 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 5.361209e-02 1.271 0 0
G1 Phase R-HSA-69236 5.460685e-02 1.263 0 0
Cyclin D associated events in G1 R-HSA-69231 5.460685e-02 1.263 0 0
COPI-mediated anterograde transport R-HSA-6807878 5.361209e-02 1.271 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 5.361209e-02 1.271 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 6.822061e-02 1.166 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.459160e-02 1.190 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 6.822061e-02 1.166 0 0
Oncogene Induced Senescence R-HSA-2559585 6.822061e-02 1.166 0 0
Signaling by FGFR R-HSA-190236 5.912454e-02 1.228 0 0
RMTs methylate histone arginines R-HSA-3214858 5.460685e-02 1.263 0 0
Signaling by FGFR4 in disease R-HSA-5655291 6.721567e-02 1.173 0 0
Ca2+ pathway R-HSA-4086398 6.142451e-02 1.212 0 0
Chaperonin-mediated protein folding R-HSA-390466 6.380911e-02 1.195 0 0
Signalling to ERKs R-HSA-187687 6.822061e-02 1.166 0 0
DAG and IP3 signaling R-HSA-1489509 5.874139e-02 1.231 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 5.245212e-02 1.280 0 0
Kinesins R-HSA-983189 6.493529e-02 1.188 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 5.162724e-02 1.287 0 0
MAPK family signaling cascades R-HSA-5683057 6.732928e-02 1.172 0 0
Regulation of beta-cell development R-HSA-186712 6.104993e-02 1.214 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 5.313648e-02 1.275 0 0
ISG15 antiviral mechanism R-HSA-1169408 6.856085e-02 1.164 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 6.142451e-02 1.212 1 0
MAP kinase activation R-HSA-450294 6.896700e-02 1.161 1 0
Autophagy R-HSA-9612973 7.065626e-02 1.151 0 0
HCMV Infection R-HSA-9609646 7.079365e-02 1.150 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 7.116458e-02 1.148 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 7.116458e-02 1.148 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 7.116458e-02 1.148 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 7.122429e-02 1.147 0 0
Signaling by NOTCH1 R-HSA-1980143 7.231197e-02 1.141 0 0
Interferon Signaling R-HSA-913531 7.312454e-02 1.136 0 0
Erythropoietin activates RAS R-HSA-9027284 7.621632e-02 1.118 0 0
SHC1 events in EGFR signaling R-HSA-180336 7.621632e-02 1.118 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 7.621632e-02 1.118 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 7.621632e-02 1.118 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 7.621632e-02 1.118 0 0
mRNA Splicing R-HSA-72172 7.641336e-02 1.117 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 7.756108e-02 1.110 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 7.925095e-02 1.101 0 0
Deubiquitination R-HSA-5688426 8.131494e-02 1.090 0 0
Insulin receptor signalling cascade R-HSA-74751 8.194056e-02 1.087 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.214037e-02 1.085 0 0
Protein folding R-HSA-391251 8.506543e-02 1.070 0 0
Myogenesis R-HSA-525793 8.528714e-02 1.069 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 8.544724e-02 1.068 0 0
Negative regulation of FLT3 R-HSA-9706369 8.571571e-02 1.067 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 8.571571e-02 1.067 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 9.162784e-02 1.038 0 0
S Phase R-HSA-69242 9.261247e-02 1.033 0 0
mRNA 3'-end processing R-HSA-72187 9.276025e-02 1.033 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 9.282179e-02 1.032 0 0
HIV Infection R-HSA-162906 9.293701e-02 1.032 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 9.468203e-02 1.024 0 0
PTK6 Expression R-HSA-8849473 9.468203e-02 1.024 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 9.468203e-02 1.024 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 9.468203e-02 1.024 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 9.568880e-02 1.019 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 9.568880e-02 1.019 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 9.568880e-02 1.019 0 0
Disorders of Developmental Biology R-HSA-9675151 9.568880e-02 1.019 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.591053e-02 1.018 0 0
Diseases of Telomere Maintenance R-HSA-9673013 9.784468e-02 1.009 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 9.784468e-02 1.009 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 9.784468e-02 1.009 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 9.784468e-02 1.009 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 9.784468e-02 1.009 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5619101 1.431202e-01 0.844 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5660686 1.431202e-01 0.844 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 1.431202e-01 0.844 0 0
Formation of annular gap junctions R-HSA-196025 1.108838e-01 0.955 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 1.277403e-01 0.894 0 0
Gap junction degradation R-HSA-190873 1.277403e-01 0.894 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.451452e-01 0.838 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.061094e-01 0.974 0 0
GAB1 signalosome R-HSA-180292 1.169506e-01 0.932 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.397838e-01 0.855 0 0
Signaling by Erythropoietin R-HSA-9006335 1.087941e-01 0.963 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 9.805043e-02 1.009 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.440618e-01 0.841 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.215849e-01 0.915 0 0
HIV Transcription Elongation R-HSA-167169 9.805043e-02 1.009 0 0
mRNA Capping R-HSA-72086 1.087941e-01 0.963 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 9.805043e-02 1.009 0 0
G-protein beta:gamma signalling R-HSA-397795 1.440618e-01 0.841 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 1.172120e-01 0.931 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.277403e-01 0.894 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.117916e-01 0.952 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 1.108838e-01 0.955 0 0
Regulation of CDH11 function R-HSA-9762292 1.451452e-01 0.838 0 0
PI3K/AKT activation R-HSA-198203 1.451452e-01 0.838 0 0
IRS-mediated signalling R-HSA-112399 1.223427e-01 0.912 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.353319e-01 0.869 1 1
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.172598e-01 0.931 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 1.169506e-01 0.932 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.259035e-01 0.900 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.046937e-01 0.980 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.172598e-01 0.931 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.420609e-01 0.848 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.420609e-01 0.848 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.420609e-01 0.848 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.420609e-01 0.848 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 1.277403e-01 0.894 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.337442e-01 0.874 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.023798e-01 0.990 0 0
FGFR1 mutant receptor activation R-HSA-1839124 1.440618e-01 0.841 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 9.784468e-02 1.009 0 0
Transport of connexins along the secretory pathway R-HSA-190827 1.431202e-01 0.844 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 1.108838e-01 0.955 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 1.281847e-01 0.892 0 0
Co-inhibition by PD-1 R-HSA-389948 1.064750e-01 0.973 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.064750e-01 0.973 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 1.440618e-01 0.841 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.228645e-01 0.911 0 0
Cellular response to chemical stress R-HSA-9711123 1.133333e-01 0.946 0 0
Nephrin family interactions R-HSA-373753 1.397838e-01 0.855 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.172598e-01 0.931 0 0
Hedgehog 'off' state R-HSA-5610787 1.239812e-01 0.907 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.273494e-01 0.895 0 0
Oligomerization of connexins into connexons R-HSA-190704 1.431202e-01 0.844 0 0
Signaling by Hippo R-HSA-2028269 1.061094e-01 0.974 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 1.021962e-01 0.991 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.420609e-01 0.848 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.277403e-01 0.894 0 0
Interleukin-17 signaling R-HSA-448424 1.117916e-01 0.952 1 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 1.277403e-01 0.894 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 1.172120e-01 0.931 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 1.410455e-01 0.851 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 1.108838e-01 0.955 0 0
Co-inhibition by CTLA4 R-HSA-389513 1.397838e-01 0.855 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.146159e-01 0.941 1 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.146159e-01 0.941 1 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.146159e-01 0.941 1 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 1.295800e-01 0.887 1 0
Programmed Cell Death R-HSA-5357801 1.254635e-01 0.901 1 0
Cytokine Signaling in Immune system R-HSA-1280215 1.058041e-01 0.975 1 0
Signaling by Leptin R-HSA-2586552 1.451452e-01 0.838 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.192483e-01 0.924 1 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.454089e-01 0.837 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.486538e-01 0.828 0 0
Signaling by TGFBR3 R-HSA-9839373 1.489026e-01 0.827 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 1.489410e-01 0.827 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.489410e-01 0.827 0 0
PLC beta mediated events R-HSA-112043 1.489410e-01 0.827 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 1.517199e-01 0.819 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 1.535047e-01 0.814 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 1.535047e-01 0.814 0 0
Heme signaling R-HSA-9707616 1.559681e-01 0.807 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.569404e-01 0.804 0 0
Interleukin-2 signaling R-HSA-9020558 1.630012e-01 0.788 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 1.631378e-01 0.787 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 1.639650e-01 0.785 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.639650e-01 0.785 0 0
GPER1 signaling R-HSA-9634597 1.651519e-01 0.782 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.709015e-01 0.767 1 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.723337e-01 0.764 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.861262e-01 0.730 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.861262e-01 0.730 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.861262e-01 0.730 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.861262e-01 0.730 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.861262e-01 0.730 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.861262e-01 0.730 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 1.861262e-01 0.730 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 1.861262e-01 0.730 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.861262e-01 0.730 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 1.861262e-01 0.730 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.861262e-01 0.730 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.861262e-01 0.730 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.861262e-01 0.730 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.861262e-01 0.730 0 0
Axonal growth stimulation R-HSA-209563 2.269762e-01 0.644 0 0
MET activates PTPN11 R-HSA-8865999 2.269762e-01 0.644 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 2.269762e-01 0.644 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 2.269762e-01 0.644 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 2.657782e-01 0.575 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.657782e-01 0.575 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.657782e-01 0.575 0 0
Signaling by LRP5 mutants R-HSA-5339717 2.657782e-01 0.575 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 3.026348e-01 0.519 0 0
NrCAM interactions R-HSA-447038 3.026348e-01 0.519 0 0
G2 Phase R-HSA-68911 3.026348e-01 0.519 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 3.026348e-01 0.519 0 0
Activation of RAC1 R-HSA-428540 1.812194e-01 0.742 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 1.812194e-01 0.742 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 1.812194e-01 0.742 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.997186e-01 0.700 0 0
GRB2 events in EGFR signaling R-HSA-179812 1.997186e-01 0.700 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 3.376433e-01 0.472 0 0
Cam-PDE 1 activation R-HSA-111957 3.376433e-01 0.472 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 3.376433e-01 0.472 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 3.376433e-01 0.472 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 3.376433e-01 0.472 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 3.376433e-01 0.472 0 0
Signaling by RNF43 mutants R-HSA-5340588 3.376433e-01 0.472 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 3.376433e-01 0.472 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 2.372707e-01 0.625 0 0
cGMP effects R-HSA-418457 2.372707e-01 0.625 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 2.372707e-01 0.625 0 0
FGFR2 alternative splicing R-HSA-6803529 1.764913e-01 0.753 0 0
Notch-HLH transcription pathway R-HSA-350054 1.764913e-01 0.753 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.764913e-01 0.753 0 0
Processive synthesis on the lagging strand R-HSA-69183 2.561954e-01 0.591 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 2.561954e-01 0.591 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 2.022782e-01 0.694 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 2.751435e-01 0.560 0 0
Phosphorylation of the APC/C R-HSA-176412 2.751435e-01 0.560 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 2.751435e-01 0.560 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 2.940652e-01 0.532 0 0
Interaction between L1 and Ankyrins R-HSA-445095 2.423984e-01 0.615 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 2.423984e-01 0.615 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 2.252076e-01 0.647 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.995892e-01 0.700 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.085584e-01 0.681 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 2.085584e-01 0.681 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 2.085584e-01 0.681 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 2.471034e-01 0.607 0 0
HIV Transcription Initiation R-HSA-167161 2.471034e-01 0.607 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 2.471034e-01 0.607 0 0
EGFR downregulation R-HSA-182971 2.975461e-01 0.526 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 2.694348e-01 0.570 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 2.921010e-01 0.534 0 0
Striated Muscle Contraction R-HSA-390522 3.393743e-01 0.469 0 0
Transcription of the HIV genome R-HSA-167172 2.009639e-01 0.697 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 2.471034e-01 0.607 0 0
G0 and Early G1 R-HSA-1538133 3.114781e-01 0.507 0 0
Cellular response to hypoxia R-HSA-1234174 3.239192e-01 0.490 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 1.902966e-01 0.721 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 1.902966e-01 0.721 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 3.377393e-01 0.471 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 1.858848e-01 0.731 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 2.372707e-01 0.625 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 1.902966e-01 0.721 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 2.423984e-01 0.615 0 0
Activation of SMO R-HSA-5635838 2.751435e-01 0.560 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 2.500406e-01 0.602 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 2.657782e-01 0.575 0 0
UCH proteinases R-HSA-5689603 2.671076e-01 0.573 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 2.516371e-01 0.599 0 0
Activation of HOX genes during differentiation R-HSA-5619507 2.516371e-01 0.599 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.997186e-01 0.700 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 3.129153e-01 0.505 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 2.751435e-01 0.560 0 0
Signaling by WNT in cancer R-HSA-4791275 3.114781e-01 0.507 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 2.638327e-01 0.579 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 3.026348e-01 0.519 0 0
Activation of AKT2 R-HSA-165158 3.026348e-01 0.519 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 3.026348e-01 0.519 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 2.184247e-01 0.661 0 0
PI3K Cascade R-HSA-109704 1.820672e-01 0.740 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 2.582211e-01 0.588 0 0
Signaling by Insulin receptor R-HSA-74752 2.750084e-01 0.561 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 2.332983e-01 0.632 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 2.423984e-01 0.615 0 0
DNA Double Strand Break Response R-HSA-5693606 1.931511e-01 0.714 1 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 2.184247e-01 0.661 0 0
MET promotes cell motility R-HSA-8875878 2.038507e-01 0.691 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 2.332983e-01 0.632 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 2.423984e-01 0.615 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.360947e-01 0.627 0 0
mRNA Editing: A to I Conversion R-HSA-75064 1.861262e-01 0.730 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.861262e-01 0.730 0 0
Regulation of cortical dendrite branching R-HSA-8985801 1.861262e-01 0.730 0 0
C6 deamination of adenosine R-HSA-75102 1.861262e-01 0.730 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 2.269762e-01 0.644 0 0
MET interacts with TNS proteins R-HSA-8875513 2.269762e-01 0.644 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 2.657782e-01 0.575 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.812194e-01 0.742 0 0
PDE3B signalling R-HSA-165160 3.376433e-01 0.472 0 0
Phosphorylation of Emi1 R-HSA-176417 3.376433e-01 0.472 0 0
PKB-mediated events R-HSA-109703 3.376433e-01 0.472 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 2.560550e-01 0.592 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 3.316535e-01 0.479 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 2.698133e-01 0.569 0 0
Trafficking of AMPA receptors R-HSA-399719 2.975461e-01 0.526 0 0
Intraflagellar transport R-HSA-5620924 3.265165e-01 0.486 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 3.380532e-01 0.471 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 3.380532e-01 0.471 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 2.187824e-01 0.660 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.174601e-01 0.498 0 0
Nuclear RNA decay R-HSA-9930044 3.254271e-01 0.488 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 3.254271e-01 0.488 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 2.561954e-01 0.591 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 2.698133e-01 0.569 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 3.039926e-01 0.517 0 0
DCC mediated attractive signaling R-HSA-418885 2.561954e-01 0.591 0 0
G-protein mediated events R-HSA-112040 1.931511e-01 0.714 0 0
Neurodegenerative Diseases R-HSA-8863678 2.022782e-01 0.694 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.022782e-01 0.694 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 3.109056e-01 0.507 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 2.657782e-01 0.575 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 1.812194e-01 0.742 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.997186e-01 0.700 0 0
Pervasive developmental disorders R-HSA-9005895 1.997186e-01 0.700 0 0
Disorders of Nervous System Development R-HSA-9697154 1.997186e-01 0.700 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 3.129153e-01 0.505 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 3.150048e-01 0.502 0 0
Vesicle-mediated transport R-HSA-5653656 2.690308e-01 0.570 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.254271e-01 0.488 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.772433e-01 0.751 1 0
Spry regulation of FGF signaling R-HSA-1295596 2.561954e-01 0.591 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.975461e-01 0.526 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.869132e-01 0.728 0 0
Interleukin-15 signaling R-HSA-8983432 1.997186e-01 0.700 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 3.181216e-01 0.497 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.154854e-01 0.667 0 0
Signaling by FGFR3 in disease R-HSA-5655332 2.423984e-01 0.615 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 3.316535e-01 0.479 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 2.975461e-01 0.526 0 0
DNA Repair R-HSA-73894 1.816904e-01 0.741 1 0
Adherens junctions interactions R-HSA-418990 3.447750e-01 0.462 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 2.893961e-01 0.539 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 2.893961e-01 0.539 0 0
Base Excision Repair R-HSA-73884 2.516619e-01 0.599 0 0
Signaling by Hedgehog R-HSA-5358351 2.802308e-01 0.552 0 0
Cardiogenesis R-HSA-9733709 3.254271e-01 0.488 0 0
Cell-Cell communication R-HSA-1500931 2.867825e-01 0.542 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 2.940652e-01 0.532 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 2.009639e-01 0.697 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.351600e-01 0.629 0 0
Ub-specific processing proteases R-HSA-5689880 2.893961e-01 0.539 0 0
Transmission across Chemical Synapses R-HSA-112315 3.178179e-01 0.498 0 0
The NLRP1 inflammasome R-HSA-844455 2.269762e-01 0.644 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 2.184247e-01 0.661 0 0
Deadenylation of mRNA R-HSA-429947 2.022782e-01 0.694 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 2.751435e-01 0.560 0 0
Differentiation of T cells R-HSA-9945266 2.751435e-01 0.560 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 2.751435e-01 0.560 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 2.154854e-01 0.667 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 2.144552e-01 0.669 0 0
G1/S Transition R-HSA-69206 1.902966e-01 0.721 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.740517e-01 0.759 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 2.142246e-01 0.669 0 0
Biotin transport and metabolism R-HSA-196780 2.561954e-01 0.591 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 2.288672e-01 0.640 0 0
Sensory processing of sound R-HSA-9659379 2.932204e-01 0.533 0 0
Other semaphorin interactions R-HSA-416700 2.561954e-01 0.591 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 3.254271e-01 0.488 0 0
RSV-host interactions R-HSA-9833110 2.516371e-01 0.599 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 2.505775e-01 0.601 0 0
Tie2 Signaling R-HSA-210993 3.316535e-01 0.479 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 1.934071e-01 0.714 0 0
Integrin signaling R-HSA-354192 3.254271e-01 0.488 0 0
Host Interactions of HIV factors R-HSA-162909 1.793923e-01 0.746 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 3.376433e-01 0.472 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 3.376433e-01 0.472 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.561954e-01 0.591 0 0
p38MAPK events R-HSA-171007 2.561954e-01 0.591 0 0
SARS-CoV-2-host interactions R-HSA-9705683 2.147048e-01 0.668 0 0
MHC class II antigen presentation R-HSA-2132295 2.772992e-01 0.557 0 0
Signaling by NOTCH3 R-HSA-9012852 2.268740e-01 0.644 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.250628e-01 0.648 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.765687e-01 0.753 1 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 2.038507e-01 0.691 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 2.505775e-01 0.601 1 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 2.505775e-01 0.601 1 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 2.705408e-01 0.568 1 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 2.705408e-01 0.568 1 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 2.950906e-01 0.530 1 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 2.362044e-01 0.627 0 0
Signaling by SCF-KIT R-HSA-1433557 2.694348e-01 0.570 0 0
MyD88-independent TLR4 cascade R-HSA-166166 2.950906e-01 0.530 1 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 2.000635e-01 0.699 1 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 2.587389e-01 0.587 1 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 3.026348e-01 0.519 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 3.376433e-01 0.472 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 3.254271e-01 0.488 0 0
Inositol phosphate metabolism R-HSA-1483249 3.099646e-01 0.509 0 0
Cytoprotection by HMOX1 R-HSA-9707564 3.287612e-01 0.483 0 0
Influenza Infection R-HSA-168255 3.248219e-01 0.488 0 0
Signaling by TGFB family members R-HSA-9006936 3.130189e-01 0.504 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.231742e-01 0.491 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 2.932204e-01 0.533 0 0
Effects of PIP2 hydrolysis R-HSA-114508 3.393743e-01 0.469 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 3.316535e-01 0.479 0 0
Death Receptor Signaling R-HSA-73887 2.762138e-01 0.559 1 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 2.009639e-01 0.697 0 0
Glycolysis R-HSA-70171 3.477712e-01 0.459 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 3.502435e-01 0.456 0 0
E2F mediated regulation of DNA replication R-HSA-113510 3.502435e-01 0.456 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 3.502435e-01 0.456 0 0
Rap1 signalling R-HSA-392517 3.502435e-01 0.456 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 3.533017e-01 0.452 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 3.533017e-01 0.452 0 0
Signaling by NOTCH2 R-HSA-1980145 3.533017e-01 0.452 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 3.533017e-01 0.452 0 0
Circadian clock R-HSA-9909396 3.542177e-01 0.451 0 0
HSF1-dependent transactivation R-HSA-3371571 3.611583e-01 0.442 0 0
Mitochondrial biogenesis R-HSA-1592230 3.630492e-01 0.440 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 3.686531e-01 0.433 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 3.686531e-01 0.433 0 0
Negative regulation of MET activity R-HSA-6807004 3.686531e-01 0.433 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 3.708964e-01 0.431 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 3.708964e-01 0.431 0 0
Signaling by LTK in cancer R-HSA-9842640 3.708964e-01 0.431 0 0
Erythropoietin activates STAT5 R-HSA-9027283 3.708964e-01 0.431 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 3.708964e-01 0.431 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.708964e-01 0.431 0 0
Nef and signal transduction R-HSA-164944 3.708964e-01 0.431 0 0
Neurofascin interactions R-HSA-447043 3.708964e-01 0.431 0 0
Opioid Signalling R-HSA-111885 3.808553e-01 0.419 0 0
FGFR2 mutant receptor activation R-HSA-1839126 3.810304e-01 0.419 0 0
Diseases of programmed cell death R-HSA-9645723 3.829240e-01 0.417 0 0
tRNA processing R-HSA-72306 3.830121e-01 0.417 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 3.842373e-01 0.415 0 0
Regulation of PTEN stability and activity R-HSA-8948751 3.842373e-01 0.415 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 3.842832e-01 0.415 0 0
Regulation of mitotic cell cycle R-HSA-453276 3.842832e-01 0.415 0 0
Lagging Strand Synthesis R-HSA-69186 3.868536e-01 0.412 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.868536e-01 0.412 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 3.948005e-01 0.404 0 0
Ovarian tumor domain proteases R-HSA-5689896 3.948005e-01 0.404 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 3.973664e-01 0.401 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 4.024820e-01 0.395 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 4.024820e-01 0.395 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 4.024820e-01 0.395 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 4.024820e-01 0.395 0 0
Regulation of PTEN localization R-HSA-8948747 4.024820e-01 0.395 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 4.024820e-01 0.395 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 4.024820e-01 0.395 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 4.048196e-01 0.393 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 4.048196e-01 0.393 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 4.048196e-01 0.393 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 4.048196e-01 0.393 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 4.138080e-01 0.383 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.144506e-01 0.383 0 0
Signaling by ERBB4 R-HSA-1236394 4.144506e-01 0.383 0 0
Viral Infection Pathways R-HSA-9824446 4.178138e-01 0.379 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.186401e-01 0.378 0 0
Ion homeostasis R-HSA-5578775 4.186401e-01 0.378 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 4.186401e-01 0.378 0 0
Stabilization of p53 R-HSA-69541 4.220813e-01 0.375 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 4.225289e-01 0.374 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 4.225289e-01 0.374 0 0
mTORC1-mediated signalling R-HSA-166208 4.225289e-01 0.374 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 4.225289e-01 0.374 0 0
RAF/MAP kinase cascade R-HSA-5673001 4.247841e-01 0.372 0 0
SARS-CoV Infections R-HSA-9679506 4.259988e-01 0.371 0 0
EPH-Ephrin signaling R-HSA-2682334 4.281428e-01 0.368 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 4.324835e-01 0.364 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 4.324835e-01 0.364 0 0
MET receptor recycling R-HSA-8875656 4.324835e-01 0.364 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 4.324835e-01 0.364 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 4.324835e-01 0.364 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 4.324835e-01 0.364 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 4.324835e-01 0.364 0 0
Adrenoceptors R-HSA-390696 4.324835e-01 0.364 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 4.324835e-01 0.364 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 4.324835e-01 0.364 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 4.324835e-01 0.364 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 4.324835e-01 0.364 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 4.355662e-01 0.361 0 0
Attenuation phase R-HSA-3371568 4.355662e-01 0.361 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 4.355662e-01 0.361 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 4.355662e-01 0.361 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 4.355662e-01 0.361 0 0
Interleukin-2 family signaling R-HSA-451927 4.355662e-01 0.361 0 0
SARS-CoV-2 Infection R-HSA-9694516 4.390679e-01 0.357 0 0
Interleukin receptor SHC signaling R-HSA-912526 4.399618e-01 0.357 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 4.399618e-01 0.357 0 0
Carnitine shuttle R-HSA-200425 4.399618e-01 0.357 0 0
Growth hormone receptor signaling R-HSA-982772 4.399618e-01 0.357 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 4.406569e-01 0.356 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 4.413299e-01 0.355 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 4.461094e-01 0.351 0 0
Clathrin-mediated endocytosis R-HSA-8856828 4.478494e-01 0.349 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 4.525773e-01 0.344 0 0
PCP/CE pathway R-HSA-4086400 4.542768e-01 0.343 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 4.571016e-01 0.340 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 4.571016e-01 0.340 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 4.608716e-01 0.336 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 4.609804e-01 0.336 0 0
Calcineurin activates NFAT R-HSA-2025928 4.609804e-01 0.336 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 4.609804e-01 0.336 1 1
Lipophagy R-HSA-9613354 4.609804e-01 0.336 0 0
p75NTR regulates axonogenesis R-HSA-193697 4.609804e-01 0.336 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 4.609804e-01 0.336 0 0
mRNA Editing R-HSA-75072 4.609804e-01 0.336 0 0
Cellular response to mitochondrial stress R-HSA-9840373 4.609804e-01 0.336 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 4.609804e-01 0.336 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 4.609804e-01 0.336 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 4.637500e-01 0.334 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 4.637500e-01 0.334 0 0
Cell junction organization R-HSA-446728 4.671577e-01 0.331 0 0
Signaling by Interleukins R-HSA-449147 4.720208e-01 0.326 1 0
PI-3K cascade:FGFR2 R-HSA-5654695 4.739338e-01 0.324 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 4.739338e-01 0.324 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 4.739338e-01 0.324 0 0
Acyl chain remodelling of PS R-HSA-1482801 4.739338e-01 0.324 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 4.739338e-01 0.324 0 0
Interleukin-7 signaling R-HSA-1266695 4.739338e-01 0.324 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 4.752630e-01 0.323 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 4.752630e-01 0.323 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 4.752630e-01 0.323 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 4.752630e-01 0.323 0 0
Telomere Maintenance R-HSA-157579 4.816502e-01 0.317 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 4.835801e-01 0.316 1 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 4.858440e-01 0.314 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.880480e-01 0.312 0 0
DNA replication initiation R-HSA-68952 4.880480e-01 0.312 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 4.880480e-01 0.312 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 4.880480e-01 0.312 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 4.880480e-01 0.312 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 4.880480e-01 0.312 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 4.880480e-01 0.312 0 0
Receptor Mediated Mitophagy R-HSA-8934903 4.880480e-01 0.312 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 4.880480e-01 0.312 0 0
Sperm Motility And Taxes R-HSA-1300642 4.880480e-01 0.312 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 4.880480e-01 0.312 0 0
Josephin domain DUBs R-HSA-5689877 4.880480e-01 0.312 0 0
Pexophagy R-HSA-9664873 4.880480e-01 0.312 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 4.904461e-01 0.309 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 4.904461e-01 0.309 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 4.904461e-01 0.309 0 0
Semaphorin interactions R-HSA-373755 4.967527e-01 0.304 0 0
Potential therapeutics for SARS R-HSA-9679191 4.977250e-01 0.303 0 0
Netrin-1 signaling R-HSA-373752 5.009985e-01 0.300 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 5.066281e-01 0.295 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 5.066281e-01 0.295 0 0
Glucose metabolism R-HSA-70326 5.119628e-01 0.291 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 5.136224e-01 0.289 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 5.136224e-01 0.289 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 5.136224e-01 0.289 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 5.137580e-01 0.289 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 5.137580e-01 0.289 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 5.137580e-01 0.289 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 5.137580e-01 0.289 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 5.137580e-01 0.289 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 5.137580e-01 0.289 0 0
LGI-ADAM interactions R-HSA-5682910 5.137580e-01 0.289 0 0
Dissolution of Fibrin Clot R-HSA-75205 5.137580e-01 0.289 0 0
Signaling by APC mutants R-HSA-4839744 5.137580e-01 0.289 0 0
Suppression of apoptosis R-HSA-9635465 5.137580e-01 0.289 0 0
Homology Directed Repair R-HSA-5693538 5.198971e-01 0.284 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 5.224714e-01 0.282 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 5.224714e-01 0.282 0 0
Pyroptosis R-HSA-5620971 5.224714e-01 0.282 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 5.260742e-01 0.279 0 0
Integration of energy metabolism R-HSA-163685 5.302795e-01 0.275 0 0
Cell-cell junction organization R-HSA-421270 5.312495e-01 0.275 0 0
PPARA activates gene expression R-HSA-1989781 5.325814e-01 0.274 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 5.379692e-01 0.269 0 0
Platelet calcium homeostasis R-HSA-418360 5.379692e-01 0.269 0 0
Signaling by GSK3beta mutants R-HSA-5339716 5.381782e-01 0.269 0 0
Negative regulation of TCF-dependent signaling by WNT ligand antagonists R-HSA-3772470 5.381782e-01 0.269 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 5.381782e-01 0.269 0 0
Signaling by AXIN mutants R-HSA-4839735 5.381782e-01 0.269 0 0
ERKs are inactivated R-HSA-202670 5.381782e-01 0.269 0 0
Signaling by AMER1 mutants R-HSA-4839748 5.381782e-01 0.269 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 5.381782e-01 0.269 0 0
DS-GAG biosynthesis R-HSA-2022923 5.381782e-01 0.269 0 0
Chromosome Maintenance R-HSA-73886 5.434049e-01 0.265 0 0
HCMV Late Events R-HSA-9610379 5.462840e-01 0.263 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 5.504372e-01 0.259 0 0
Co-stimulation by CD28 R-HSA-389356 5.504372e-01 0.259 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 5.504372e-01 0.259 0 0
DAP12 signaling R-HSA-2424491 5.531162e-01 0.257 0 0
Interleukin-37 signaling R-HSA-9008059 5.531162e-01 0.257 0 0
Nucleotide Excision Repair R-HSA-5696398 5.586508e-01 0.253 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.588079e-01 0.253 0 0
Leading Strand Synthesis R-HSA-69109 5.613735e-01 0.251 0 0
Polymerase switching R-HSA-69091 5.613735e-01 0.251 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 5.613735e-01 0.251 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 5.613735e-01 0.251 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 5.613735e-01 0.251 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 5.613735e-01 0.251 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 5.613735e-01 0.251 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 5.613735e-01 0.251 0 0
Regulation of IFNG signaling R-HSA-877312 5.613735e-01 0.251 0 0
Downstream signal transduction R-HSA-186763 5.679087e-01 0.246 0 0
Hedgehog 'on' state R-HSA-5632684 5.800138e-01 0.237 0 0
DNA strand elongation R-HSA-69190 5.823440e-01 0.235 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 5.834050e-01 0.234 0 0
Adenylate cyclase activating pathway R-HSA-170660 5.834050e-01 0.234 0 0
Formation of axial mesoderm R-HSA-9796292 5.834050e-01 0.234 0 0
Frs2-mediated activation R-HSA-170968 5.834050e-01 0.234 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 5.834050e-01 0.234 0 0
Processing of SMDT1 R-HSA-8949664 5.834050e-01 0.234 0 0
Interleukin-6 signaling R-HSA-1059683 5.834050e-01 0.234 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 5.834050e-01 0.234 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 5.853997e-01 0.233 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 5.855544e-01 0.232 0 0
Signaling by ROBO receptors R-HSA-376176 5.913244e-01 0.228 0 0
G2/M Checkpoints R-HSA-69481 5.962539e-01 0.225 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 5.964206e-01 0.224 0 0
Activation of ATR in response to replication stress R-HSA-176187 5.964206e-01 0.224 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 5.968636e-01 0.224 0 0
Removal of the Flap Intermediate R-HSA-69166 6.043313e-01 0.219 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 6.043313e-01 0.219 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 6.043313e-01 0.219 0 0
Signal regulatory protein family interactions R-HSA-391160 6.043313e-01 0.219 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 6.043313e-01 0.219 0 0
Smooth Muscle Contraction R-HSA-445355 6.079693e-01 0.216 0 0
Signaling by NOTCH4 R-HSA-9013694 6.091300e-01 0.215 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 6.101382e-01 0.215 0 0
Resolution of D-Loop Structures R-HSA-5693537 6.101382e-01 0.215 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 6.101382e-01 0.215 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 6.185554e-01 0.209 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 6.185554e-01 0.209 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 6.188693e-01 0.208 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 6.234973e-01 0.205 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 6.234973e-01 0.205 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 6.234973e-01 0.205 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 6.242075e-01 0.205 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 6.242075e-01 0.205 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 6.242075e-01 0.205 0 0
G beta:gamma signalling through BTK R-HSA-8964315 6.242075e-01 0.205 0 0
Telomere C-strand synthesis initiation R-HSA-174430 6.242075e-01 0.205 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 6.242075e-01 0.205 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 6.242075e-01 0.205 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 6.242075e-01 0.205 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 6.242075e-01 0.205 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 6.278373e-01 0.202 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 6.298627e-01 0.201 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 6.298627e-01 0.201 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 6.369737e-01 0.196 0 0
Toll-like Receptor Cascades R-HSA-168898 6.399689e-01 0.194 1 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 6.400450e-01 0.194 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 6.400450e-01 0.194 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 6.430865e-01 0.192 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 6.430865e-01 0.192 0 0
Prolonged ERK activation events R-HSA-169893 6.430865e-01 0.192 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 6.430865e-01 0.192 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 6.430865e-01 0.192 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 6.430865e-01 0.192 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 6.430865e-01 0.192 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 6.430865e-01 0.192 1 1
Killing mechanisms R-HSA-9664420 6.430865e-01 0.192 1 0
Nuclear Receptor transcription pathway R-HSA-383280 6.459633e-01 0.190 0 0
RNA Polymerase I Transcription R-HSA-73864 6.459633e-01 0.190 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 6.491464e-01 0.188 0 0
RUNX2 regulates bone development R-HSA-8941326 6.491464e-01 0.188 0 0
G1/S-Specific Transcription R-HSA-69205 6.491464e-01 0.188 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 6.491464e-01 0.188 0 0
RNA Polymerase III Transcription R-HSA-74158 6.491464e-01 0.188 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 6.610181e-01 0.180 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 6.610181e-01 0.180 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 6.610181e-01 0.180 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 6.610181e-01 0.180 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 6.610181e-01 0.180 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 6.610181e-01 0.180 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 6.634967e-01 0.178 0 0
Extension of Telomeres R-HSA-180786 6.702317e-01 0.174 0 0
Processing of DNA double-strand break ends R-HSA-5693607 6.720387e-01 0.173 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 6.780498e-01 0.169 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 6.780498e-01 0.169 0 0
Glycogen storage diseases R-HSA-3229121 6.780498e-01 0.169 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 6.780498e-01 0.169 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 6.780498e-01 0.169 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 6.780498e-01 0.169 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 6.780498e-01 0.169 0 0
Uptake and function of anthrax toxins R-HSA-5210891 6.780498e-01 0.169 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 6.780498e-01 0.169 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 6.780498e-01 0.169 0 0
tRNA Aminoacylation R-HSA-379724 6.798720e-01 0.168 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 6.849894e-01 0.164 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 6.849894e-01 0.164 0 0
Formation of paraxial mesoderm R-HSA-9793380 6.893015e-01 0.162 0 0
Interferon gamma signaling R-HSA-877300 6.904067e-01 0.161 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 6.942268e-01 0.158 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 6.942268e-01 0.158 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 6.942268e-01 0.158 0 0
Presynaptic function of Kainate receptors R-HSA-500657 6.942268e-01 0.158 0 0
PKA activation in glucagon signalling R-HSA-164378 6.942268e-01 0.158 0 0
PKA activation R-HSA-163615 6.942268e-01 0.158 0 0
Mismatch Repair R-HSA-5358508 6.942268e-01 0.158 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 6.962509e-01 0.157 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 6.962509e-01 0.157 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 6.962509e-01 0.157 0 0
Glycogen metabolism R-HSA-8982491 6.962509e-01 0.157 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 6.962509e-01 0.157 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.967583e-01 0.157 0 0
Developmental Cell Lineages R-HSA-9734767 6.972185e-01 0.157 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 6.985210e-01 0.156 0 0
Signaling by PDGF R-HSA-186797 6.985210e-01 0.156 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 6.985210e-01 0.156 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.050829e-01 0.152 0 0
Response of endothelial cells to shear stress R-HSA-9860931 7.050829e-01 0.152 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 7.071771e-01 0.150 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 7.071771e-01 0.150 0 0
Regulation of signaling by CBL R-HSA-912631 7.095918e-01 0.149 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 7.095918e-01 0.149 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 7.095918e-01 0.149 0 0
Pyrimidine biosynthesis R-HSA-500753 7.095918e-01 0.149 0 0
Specification of the neural plate border R-HSA-9834899 7.095918e-01 0.149 0 0
Maturation of nucleoprotein R-HSA-9694631 7.095918e-01 0.149 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 7.095918e-01 0.149 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 7.124807e-01 0.147 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 7.177731e-01 0.144 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 7.177731e-01 0.144 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 7.177731e-01 0.144 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 7.177731e-01 0.144 0 0
Heme biosynthesis R-HSA-189451 7.177731e-01 0.144 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 7.241857e-01 0.140 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 7.241857e-01 0.140 0 0
Glycogen synthesis R-HSA-3322077 7.241857e-01 0.140 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 7.241857e-01 0.140 0 0
Formation of definitive endoderm R-HSA-9823730 7.241857e-01 0.140 0 0
Signal transduction by L1 R-HSA-445144 7.241857e-01 0.140 0 0
Signaling by NODAL R-HSA-1181150 7.241857e-01 0.140 0 0
Platelet homeostasis R-HSA-418346 7.258225e-01 0.139 0 0
Activation of GABAB receptors R-HSA-991365 7.280447e-01 0.138 0 0
GABA B receptor activation R-HSA-977444 7.280447e-01 0.138 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 7.280447e-01 0.138 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 7.280447e-01 0.138 0 0
Depyrimidination R-HSA-73928 7.280447e-01 0.138 0 0
SLC transporter disorders R-HSA-5619102 7.353213e-01 0.134 0 0
Defective pyroptosis R-HSA-9710421 7.379977e-01 0.132 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 7.379977e-01 0.132 0 0
Response of Mtb to phagocytosis R-HSA-9637690 7.379977e-01 0.132 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 7.380470e-01 0.132 0 0
G-protein activation R-HSA-202040 7.380470e-01 0.132 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 7.380470e-01 0.132 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 7.380470e-01 0.132 0 0
Basigin interactions R-HSA-210991 7.380470e-01 0.132 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 7.380470e-01 0.132 0 0
Early Phase of HIV Life Cycle R-HSA-162594 7.380470e-01 0.132 0 0
Stimuli-sensing channels R-HSA-2672351 7.390547e-01 0.131 0 0
EPHB-mediated forward signaling R-HSA-3928662 7.476380e-01 0.126 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 7.476380e-01 0.126 0 0
DAP12 interactions R-HSA-2172127 7.476380e-01 0.126 0 0
Regulated Necrosis R-HSA-5218859 7.494948e-01 0.125 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 7.512125e-01 0.124 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 7.512125e-01 0.124 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 7.512125e-01 0.124 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 7.512125e-01 0.124 0 0
Mitochondrial calcium ion transport R-HSA-8949215 7.512125e-01 0.124 0 0
Muscle contraction R-HSA-397014 7.545393e-01 0.122 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 7.569720e-01 0.121 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 7.569720e-01 0.121 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 7.569720e-01 0.121 0 0
Fanconi Anemia Pathway R-HSA-6783310 7.569720e-01 0.121 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 7.572826e-01 0.121 0 0
G alpha (s) signalling events R-HSA-418555 7.610251e-01 0.119 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 7.637170e-01 0.117 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 7.637170e-01 0.117 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 7.637170e-01 0.117 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 7.637170e-01 0.117 0 0
Signaling by KIT in disease R-HSA-9669938 7.637170e-01 0.117 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 7.637170e-01 0.117 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 7.648738e-01 0.116 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 7.648738e-01 0.116 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 7.648738e-01 0.116 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 7.660062e-01 0.116 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 7.660062e-01 0.116 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 7.660062e-01 0.116 0 0
Regulation of TNFR1 signaling R-HSA-5357905 7.660062e-01 0.116 0 0
Neuronal System R-HSA-112316 7.671907e-01 0.115 0 0
Adaptive Immune System R-HSA-1280218 7.732885e-01 0.112 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 7.747470e-01 0.111 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 7.747470e-01 0.111 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 7.755938e-01 0.110 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.755938e-01 0.110 0 0
Organic anion transport by SLCO transporters R-HSA-879518 7.755938e-01 0.110 0 0
Syndecan interactions R-HSA-3000170 7.755938e-01 0.110 0 0
Thromboxane signalling through TP receptor R-HSA-428930 7.868743e-01 0.104 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.868743e-01 0.104 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 7.868743e-01 0.104 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 7.868743e-01 0.104 0 0
TNFs bind their physiological receptors R-HSA-5669034 7.868743e-01 0.104 0 0
Interleukin-6 family signaling R-HSA-6783589 7.868743e-01 0.104 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 7.882916e-01 0.103 0 0
G alpha (q) signalling events R-HSA-416476 7.911698e-01 0.102 0 0
Degradation of CDH1 R-HSA-9766229 7.913752e-01 0.102 0 0
DNA Damage Bypass R-HSA-73893 7.913752e-01 0.102 0 0
G protein gated Potassium channels R-HSA-1296059 7.975884e-01 0.098 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.975884e-01 0.098 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.975884e-01 0.098 0 0
Laminin interactions R-HSA-3000157 7.975884e-01 0.098 0 0
Long-term potentiation R-HSA-9620244 7.975884e-01 0.098 0 0
Sema4D in semaphorin signaling R-HSA-400685 7.975884e-01 0.098 0 0
Beta-oxidation of pristanoyl-CoA R-HSA-389887 7.975884e-01 0.098 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 7.975884e-01 0.098 0 0
Fertilization R-HSA-1187000 7.975884e-01 0.098 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 7.975884e-01 0.098 0 0
Regulation of RAS by GAPs R-HSA-5658442 7.992762e-01 0.097 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 7.999719e-01 0.097 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 8.069107e-01 0.093 0 0
The phototransduction cascade R-HSA-2514856 8.069107e-01 0.093 0 0
MET activates PTK2 signaling R-HSA-8874081 8.077645e-01 0.093 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 8.077645e-01 0.093 0 0
Metalloprotease DUBs R-HSA-5689901 8.077645e-01 0.093 0 0
TRP channels R-HSA-3295583 8.077645e-01 0.093 0 0
Attachment of bacteria to epithelial cells R-HSA-9638630 8.077645e-01 0.093 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 8.077645e-01 0.093 0 0
Suppression of phagosomal maturation R-HSA-9637687 8.077645e-01 0.093 0 0
Regulation of insulin secretion R-HSA-422356 8.115663e-01 0.091 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 8.142856e-01 0.089 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.142856e-01 0.089 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 8.142856e-01 0.089 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 8.142856e-01 0.089 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 8.174295e-01 0.088 0 0
Cristae formation R-HSA-8949613 8.174295e-01 0.088 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 8.174295e-01 0.088 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 8.174295e-01 0.088 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 8.214078e-01 0.085 0 0
Platelet activation, signaling and aggregation R-HSA-76002 8.264957e-01 0.083 0 0
Telomere Extension By Telomerase R-HSA-171319 8.266092e-01 0.083 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.266092e-01 0.083 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 8.266092e-01 0.083 0 0
Pyrimidine salvage R-HSA-73614 8.266092e-01 0.083 0 0
Inflammasomes R-HSA-622312 8.266092e-01 0.083 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 8.282839e-01 0.082 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 8.282839e-01 0.082 0 0
PI Metabolism R-HSA-1483255 8.327068e-01 0.080 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 8.349206e-01 0.078 0 0
DNA methylation R-HSA-5334118 8.353279e-01 0.078 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 8.353279e-01 0.078 0 0
Termination of translesion DNA synthesis R-HSA-5656169 8.353279e-01 0.078 0 0
Glucagon-type ligand receptors R-HSA-420092 8.353279e-01 0.078 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 8.353279e-01 0.078 0 0
TNF signaling R-HSA-75893 8.413247e-01 0.075 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 8.425138e-01 0.074 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 8.436087e-01 0.074 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.436087e-01 0.074 0 0
Activation of the pre-replicative complex R-HSA-68962 8.436087e-01 0.074 0 0
Regulation of CDH1 Function R-HSA-9764561 8.475028e-01 0.072 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.513678e-01 0.070 0 0
Budding and maturation of HIV virion R-HSA-162588 8.514735e-01 0.070 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 8.514735e-01 0.070 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 8.514735e-01 0.070 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 8.514735e-01 0.070 0 0
Dual incision in TC-NER R-HSA-6782135 8.534613e-01 0.069 0 0
SARS-CoV-1-host interactions R-HSA-9692914 8.563147e-01 0.067 0 0
Oncogenic MAPK signaling R-HSA-6802957 8.570643e-01 0.067 0 0
Gastrulation R-HSA-9758941 8.589326e-01 0.066 0 0
Inwardly rectifying K+ channels R-HSA-1296065 8.589433e-01 0.066 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.589433e-01 0.066 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 8.589433e-01 0.066 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 8.589433e-01 0.066 0 0
Amino acid transport across the plasma membrane R-HSA-352230 8.592068e-01 0.066 0 0
Synthesis of DNA R-HSA-69239 8.606806e-01 0.065 0 0
GABA receptor activation R-HSA-977443 8.647455e-01 0.063 0 0
Recycling of bile acids and salts R-HSA-159418 8.660378e-01 0.062 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 8.660378e-01 0.062 0 0
Regulation of necroptotic cell death R-HSA-5675482 8.660378e-01 0.062 0 0
Aquaporin-mediated transport R-HSA-445717 8.700838e-01 0.060 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 8.700838e-01 0.060 0 0
Nucleotide salvage R-HSA-8956321 8.700838e-01 0.060 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 8.727759e-01 0.059 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.727759e-01 0.059 0 0
Vpu mediated degradation of CD4 R-HSA-180534 8.727759e-01 0.059 0 0
Miscellaneous transport and binding events R-HSA-5223345 8.727759e-01 0.059 0 0
Glutamate and glutamine metabolism R-HSA-8964539 8.727759e-01 0.059 0 0
NCAM signaling for neurite out-growth R-HSA-375165 8.752277e-01 0.058 0 0
Signal amplification R-HSA-392518 8.791755e-01 0.056 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 8.791755e-01 0.056 0 0
eNOS activation R-HSA-203615 8.791755e-01 0.056 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 8.791755e-01 0.056 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 8.791755e-01 0.056 0 0
Mitophagy R-HSA-5205647 8.791755e-01 0.056 0 0
RAF activation R-HSA-5673000 8.791755e-01 0.056 0 0
Hyaluronan metabolism R-HSA-2142845 8.791755e-01 0.056 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 8.791755e-01 0.056 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 8.801833e-01 0.055 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.808452e-01 0.055 1 1
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 8.810419e-01 0.055 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 8.852536e-01 0.053 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 8.852536e-01 0.053 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.852536e-01 0.053 0 0
Regulation of Apoptosis R-HSA-169911 8.852536e-01 0.053 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 8.852536e-01 0.053 0 0
PERK regulates gene expression R-HSA-381042 8.852536e-01 0.053 0 0
Transferrin endocytosis and recycling R-HSA-917977 8.852536e-01 0.053 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 8.852536e-01 0.053 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 8.892595e-01 0.051 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 8.895531e-01 0.051 0 0
HSF1 activation R-HSA-3371511 8.910262e-01 0.050 0 0
PRC2 methylates histones and DNA R-HSA-212300 8.910262e-01 0.050 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 8.910262e-01 0.050 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 8.910262e-01 0.050 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 8.939789e-01 0.049 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 8.957080e-01 0.048 0 0
Cleavage of the damaged purine R-HSA-110331 8.965088e-01 0.047 0 0
Degradation of DVL R-HSA-4641258 8.965088e-01 0.047 0 0
Degradation of AXIN R-HSA-4641257 8.965088e-01 0.047 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 8.965088e-01 0.047 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 8.965088e-01 0.047 0 0
SLC-mediated transport of organic cations R-HSA-549127 8.965088e-01 0.047 0 0
Collagen chain trimerization R-HSA-8948216 8.965088e-01 0.047 0 0
Metabolism of folate and pterines R-HSA-196757 8.965088e-01 0.047 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 8.982392e-01 0.047 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 8.982392e-01 0.047 0 0
SLC-mediated transport of amino acids R-HSA-9958863 8.982392e-01 0.047 0 0
Interferon alpha/beta signaling R-HSA-909733 8.984266e-01 0.047 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.993649e-01 0.046 0 0
Hemostasis R-HSA-109582 9.001900e-01 0.046 0 0
Depurination R-HSA-73927 9.017158e-01 0.045 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.017158e-01 0.045 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.017158e-01 0.045 0 0
Biofilm formation R-HSA-9931953 9.017158e-01 0.045 0 0
Purine salvage R-HSA-74217 9.017158e-01 0.045 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 9.017158e-01 0.045 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 9.017158e-01 0.045 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.023396e-01 0.045 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.066612e-01 0.043 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.066612e-01 0.043 0 0
RAS processing R-HSA-9648002 9.066612e-01 0.043 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 9.075646e-01 0.042 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.128633e-01 0.040 0 0
Metabolism of porphyrins R-HSA-189445 9.137336e-01 0.039 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.158187e-01 0.038 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.158187e-01 0.038 0 0
Maturation of spike protein R-HSA-9694548 9.158187e-01 0.038 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.158187e-01 0.038 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 9.158187e-01 0.038 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.200552e-01 0.036 0 0
Intra-Golgi traffic R-HSA-6811438 9.200552e-01 0.036 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.200552e-01 0.036 0 0
Negative regulation of MAPK pathway R-HSA-5675221 9.200552e-01 0.036 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.206237e-01 0.036 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 9.231826e-01 0.035 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.238713e-01 0.034 0 0
Iron uptake and transport R-HSA-917937 9.269933e-01 0.033 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.279001e-01 0.032 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.313800e-01 0.031 0 0
Amine ligand-binding receptors R-HSA-375280 9.315292e-01 0.031 0 0
Proteasome assembly R-HSA-9907900 9.315292e-01 0.031 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.315292e-01 0.031 0 0
Translation of Structural Proteins R-HSA-9694635 9.328783e-01 0.030 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 9.349759e-01 0.029 0 0
Nucleosome assembly R-HSA-774815 9.349759e-01 0.029 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.349759e-01 0.029 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.349759e-01 0.029 0 0
Somitogenesis R-HSA-9824272 9.349759e-01 0.029 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.349759e-01 0.029 0 0
Interleukin-10 signaling R-HSA-6783783 9.356496e-01 0.029 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 9.382493e-01 0.028 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 9.382493e-01 0.028 0 0
Signaling downstream of RAS mutants R-HSA-9649948 9.382493e-01 0.028 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 9.382493e-01 0.028 0 0
Signaling by RAS mutants R-HSA-6802949 9.382493e-01 0.028 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.386341e-01 0.028 1 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.413581e-01 0.026 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.413581e-01 0.026 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.440578e-01 0.025 0 0
Cardiac conduction R-HSA-5576891 9.442136e-01 0.025 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.461235e-01 0.024 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.471146e-01 0.024 0 0
Cellular response to starvation R-HSA-9711097 9.479509e-01 0.023 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.479527e-01 0.023 0 0
DNA Replication Pre-Initiation R-HSA-69002 9.481181e-01 0.023 0 0
Azathioprine ADME R-HSA-9748787 9.497776e-01 0.022 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.497776e-01 0.022 0 0
Protein-protein interactions at synapses R-HSA-6794362 9.522170e-01 0.021 0 0
Complex IV assembly R-HSA-9864848 9.523066e-01 0.021 0 0
Cytosolic sulfonation of small molecules R-HSA-156584 9.523066e-01 0.021 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.523066e-01 0.021 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 9.536970e-01 0.021 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 9.536970e-01 0.021 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.546839e-01 0.020 0 0
Orc1 removal from chromatin R-HSA-68949 9.547084e-01 0.020 0 0
Neurexins and neuroligins R-HSA-6794361 9.547084e-01 0.020 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.547084e-01 0.020 0 0
XBP1(S) activates chaperone genes R-HSA-381038 9.561463e-01 0.019 0 0
Ion channel transport R-HSA-983712 9.563574e-01 0.019 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.569894e-01 0.019 0 0
Nucleotide biosynthesis R-HSA-8956320 9.569894e-01 0.019 0 0
Selenoamino acid metabolism R-HSA-2408522 9.571260e-01 0.019 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.587113e-01 0.018 0 0
Translation initiation complex formation R-HSA-72649 9.591557e-01 0.018 0 0
Peptide chain elongation R-HSA-156902 9.597654e-01 0.018 0 0
Paracetamol ADME R-HSA-9753281 9.612130e-01 0.017 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.612130e-01 0.017 0 0
ER-Phagosome pathway R-HSA-1236974 9.614658e-01 0.017 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.617664e-01 0.017 0 0
Downstream TCR signaling R-HSA-202424 9.630971e-01 0.016 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 9.631668e-01 0.016 0 0
Neddylation R-HSA-8951664 9.645415e-01 0.016 0 0
Peptide hormone metabolism R-HSA-2980736 9.646080e-01 0.016 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.646620e-01 0.016 0 0
Synthesis of PA R-HSA-1483166 9.650222e-01 0.015 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.661631e-01 0.015 0 0
IRE1alpha activates chaperones R-HSA-381070 9.661631e-01 0.015 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 9.667843e-01 0.015 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.667843e-01 0.015 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.670638e-01 0.015 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.676027e-01 0.014 0 0
Peroxisomal protein import R-HSA-9033241 9.684578e-01 0.014 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.684578e-01 0.014 0 0
Assembly of the pre-replicative complex R-HSA-68867 9.689832e-01 0.014 0 0
Metabolism of polyamines R-HSA-351202 9.700470e-01 0.013 0 0
Collagen formation R-HSA-1474290 9.703070e-01 0.013 0 0
GPCR downstream signalling R-HSA-388396 9.711910e-01 0.013 0 0
SARS-CoV-1 Infection R-HSA-9678108 9.711925e-01 0.013 0 0
Endogenous sterols R-HSA-211976 9.715563e-01 0.013 0 0
Collagen degradation R-HSA-1442490 9.715563e-01 0.013 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.715763e-01 0.013 0 0
Formation of a pool of free 40S subunits R-HSA-72689 9.727932e-01 0.012 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.727932e-01 0.012 0 0
Eukaryotic Translation Termination R-HSA-72764 9.727932e-01 0.012 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.739597e-01 0.011 0 0
Complex I biogenesis R-HSA-6799198 9.743507e-01 0.011 0 0
rRNA processing R-HSA-72312 9.745401e-01 0.011 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.752627e-01 0.011 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.752627e-01 0.011 0 0
Interleukin-1 family signaling R-HSA-446652 9.752627e-01 0.011 1 0
Ion transport by P-type ATPases R-HSA-936837 9.756433e-01 0.011 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 9.756433e-01 0.011 0 0
DNA Replication R-HSA-69306 9.761471e-01 0.010 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.761494e-01 0.010 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.771765e-01 0.010 0 0
ABC-family proteins mediated transport R-HSA-382556 9.781607e-01 0.010 0 0
Selenocysteine synthesis R-HSA-2408557 9.791037e-01 0.009 0 0
Interleukin-1 signaling R-HSA-9020702 9.791037e-01 0.009 0 0
Viral mRNA Translation R-HSA-192823 9.808729e-01 0.008 0 0
COPII-mediated vesicle transport R-HSA-204005 9.821416e-01 0.008 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.821416e-01 0.008 0 0
Metabolism of cofactors R-HSA-8978934 9.830420e-01 0.007 0 0
ECM proteoglycans R-HSA-3000178 9.830420e-01 0.007 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.838970e-01 0.007 0 0
Infectious disease R-HSA-5663205 9.844674e-01 0.007 1 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.847090e-01 0.007 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 9.853518e-01 0.006 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 9.853518e-01 0.006 0 0
Ribosome-associated quality control R-HSA-9948299 9.863374e-01 0.006 0 0
TCR signaling R-HSA-202403 9.866042e-01 0.006 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.866042e-01 0.006 0 0
Unfolded Protein Response (UPR) R-HSA-381119 9.868805e-01 0.006 0 0
ABC transporter disorders R-HSA-5619084 9.881951e-01 0.005 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.881951e-01 0.005 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.887905e-01 0.005 0 0
Eukaryotic Translation Initiation R-HSA-72613 9.906502e-01 0.004 0 0
Cap-dependent Translation Initiation R-HSA-72737 9.906502e-01 0.004 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.913469e-01 0.004 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.925438e-01 0.003 0 0
Neutrophil degranulation R-HSA-6798695 9.927760e-01 0.003 0 0
Formation of the cornified envelope R-HSA-6809371 9.934941e-01 0.003 0 0
Neurotransmitter release cycle R-HSA-112310 9.939781e-01 0.003 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.939781e-01 0.003 0 0
Signaling by GPCR R-HSA-372790 9.943321e-01 0.002 0 0
Platelet degranulation R-HSA-114608 9.945788e-01 0.002 0 0
Immune System R-HSA-168256 9.947832e-01 0.002 1 0
Post-translational protein modification R-HSA-597592 9.951721e-01 0.002 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.955032e-01 0.002 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.958815e-01 0.002 0 0
Potassium Channels R-HSA-1296071 9.960215e-01 0.002 0 0
Sphingolipid metabolism R-HSA-428157 9.963227e-01 0.002 0 0
Phospholipid metabolism R-HSA-1483257 9.967496e-01 0.001 0 0
Metabolism of nucleotides R-HSA-15869 9.968838e-01 0.001 0 0
Disease R-HSA-1643685 9.977449e-01 0.001 1 0
FCERI mediated NF-kB activation R-HSA-2871837 9.978426e-01 0.001 0 0
Visual phototransduction R-HSA-2187338 9.981234e-01 0.001 0 0
Arachidonate metabolism R-HSA-2142753 9.985135e-01 0.001 0 0
Protein localization R-HSA-9609507 9.985813e-01 0.001 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.987288e-01 0.001 0 0
Metabolism of steroids R-HSA-8957322 9.988322e-01 0.001 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.989055e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.990934e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.991800e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.991998e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.993040e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.993182e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.994166e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.994715e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.994715e-01 0.000 0 0
Reproduction R-HSA-1474165 9.994742e-01 0.000 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.994960e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.995830e-01 0.000 0 0
Leishmania phagocytosis R-HSA-9664417 9.997031e-01 0.000 0 0
Parasite infection R-HSA-9664407 9.997031e-01 0.000 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.997031e-01 0.000 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.997182e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.997958e-01 0.000 0 0
Leishmania infection R-HSA-9658195 9.998720e-01 0.000 1 0
Parasitic Infection Pathways R-HSA-9824443 9.998720e-01 0.000 1 0
Keratinization R-HSA-6805567 9.998956e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.999308e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999509e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999729e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999750e-01 0.000 0 0
Translation R-HSA-72766 9.999794e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999825e-01 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 9.999900e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999956e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999960e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999974e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999975e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.999983e-01 0.000 1 0
Phase II - Conjugation of compounds R-HSA-156580 9.999985e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.999995e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999998e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999999e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 1.000000e+00 0.000 1 1
Activation of BMF and translocation to mitochondria R-HSA-139910 1.000000e+00 0.000 1 1
NRIF signals cell death from the nucleus R-HSA-205043 1.000000e+00 0.000 1 1
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 1.000000e+00 0.000 1 1
Interleukin-38 signaling R-HSA-9007892 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Recycling pathway of L1 R-HSA-437239 1.861973e-07 6.730 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 3.236283e-07 6.490 0 0
Aggrephagy R-HSA-9646399 2.021787e-06 5.694 0 0
Cell Cycle, Mitotic R-HSA-69278 2.133130e-06 5.671 0 0
Chromatin organization R-HSA-4839726 2.123565e-06 5.673 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.344354e-06 5.630 0 0
Transport of connexons to the plasma membrane R-HSA-190872 3.558916e-06 5.449 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 5.336444e-06 5.273 0 0
Cell Cycle R-HSA-1640170 5.161004e-06 5.287 0 0
Cellular response to heat stress R-HSA-3371556 7.445219e-06 5.128 0 0
Chromatin modifying enzymes R-HSA-3247509 1.265092e-05 4.898 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.362867e-05 4.866 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 2.235755e-05 4.651 0 0
Gap junction trafficking and regulation R-HSA-157858 2.133783e-05 4.671 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.268497e-05 4.486 1 0
Post-chaperonin tubulin folding pathway R-HSA-389977 4.368284e-05 4.360 0 0
PKR-mediated signaling R-HSA-9833482 4.214470e-05 4.375 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 6.387806e-05 4.195 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 9.531496e-05 4.021 0 0
Gap junction trafficking R-HSA-190828 1.048873e-04 3.979 0 0
M Phase R-HSA-68886 1.184267e-04 3.927 0 0
Selective autophagy R-HSA-9663891 1.526179e-04 3.816 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.613900e-04 3.792 0 0
L1CAM interactions R-HSA-373760 1.838538e-04 3.736 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.900718e-04 3.721 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.307377e-04 3.637 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 2.452817e-04 3.610 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.487119e-04 3.604 0 0
NRAGE signals death through JNK R-HSA-193648 2.654294e-04 3.576 1 1
Mitotic Prometaphase R-HSA-68877 2.992314e-04 3.524 0 0
Nuclear Envelope Breakdown R-HSA-2980766 3.115918e-04 3.506 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.145673e-04 3.502 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 3.064070e-04 3.514 0 0
Regulation of TP53 Expression R-HSA-6804754 3.312887e-04 3.480 0 0
Signal Transduction R-HSA-162582 3.350700e-04 3.475 1 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.798781e-04 3.420 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.798781e-04 3.420 0 0
HSF1-dependent transactivation R-HSA-3371571 3.712680e-04 3.430 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.918844e-04 3.407 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 3.780967e-04 3.422 1 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 4.194129e-04 3.377 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 4.106826e-04 3.386 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 4.675947e-04 3.330 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 5.056170e-04 3.296 0 0
Attenuation phase R-HSA-3371568 5.056170e-04 3.296 0 0
Mitotic Anaphase R-HSA-68882 4.739097e-04 3.324 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 5.100767e-04 3.292 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 5.127781e-04 3.290 0 0
Apoptotic execution phase R-HSA-75153 5.186416e-04 3.285 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 5.358286e-04 3.271 0 0
Gap junction assembly R-HSA-190861 5.716501e-04 3.243 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 6.085498e-04 3.216 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 6.486735e-04 3.188 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 6.603187e-04 3.180 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 6.943372e-04 3.158 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 6.978723e-04 3.156 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 7.232005e-04 3.141 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 7.720979e-04 3.112 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.014286e-04 3.096 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 9.467658e-04 3.024 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 9.467658e-04 3.024 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 9.365218e-04 3.028 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 9.617759e-04 3.017 0 0
Separation of Sister Chromatids R-HSA-2467813 9.777142e-04 3.010 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.034848e-03 2.985 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.034926e-03 2.985 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.047038e-03 2.980 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.079524e-03 2.967 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.180648e-03 2.928 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 1.200226e-03 2.921 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.374321e-03 2.862 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.374321e-03 2.862 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.339222e-03 2.873 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.393494e-03 2.856 0 0
Kinesins R-HSA-983189 1.420909e-03 2.847 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 1.479671e-03 2.830 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 1.479671e-03 2.830 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.627094e-03 2.789 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.673844e-03 2.776 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 1.682088e-03 2.774 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.793132e-03 2.746 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 1.848024e-03 2.733 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.823847e-03 2.739 1 1
Signaling by ALK in cancer R-HSA-9700206 1.823847e-03 2.739 1 0
Interferon Signaling R-HSA-913531 1.873637e-03 2.727 0 0
Nuclear import of Rev protein R-HSA-180746 1.998189e-03 2.699 0 0
mTORC1-mediated signalling R-HSA-166208 2.118411e-03 2.674 0 0
Chaperonin-mediated protein folding R-HSA-390466 2.292427e-03 2.640 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 2.371379e-03 2.625 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.575520e-03 2.589 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.684287e-03 2.571 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.675348e-03 2.573 0 0
HCMV Early Events R-HSA-9609690 2.810504e-03 2.551 0 0
COPI-mediated anterograde transport R-HSA-6807878 2.967121e-03 2.528 0 0
Mitotic Prophase R-HSA-68875 3.198421e-03 2.495 0 0
Cellular Senescence R-HSA-2559583 3.401439e-03 2.468 1 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.285013e-03 2.483 0 0
Membrane Trafficking R-HSA-199991 3.425103e-03 2.465 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 3.285013e-03 2.483 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 3.339506e-03 2.476 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 3.557989e-03 2.449 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.896696e-03 2.409 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.896696e-03 2.409 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 3.929699e-03 2.406 1 0
Diseases of mitotic cell cycle R-HSA-9675126 3.962650e-03 2.402 0 0
Oncogenic MAPK signaling R-HSA-6802957 3.979169e-03 2.400 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 4.239346e-03 2.373 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 4.128804e-03 2.384 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 4.381723e-03 2.358 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 4.204101e-03 2.376 0 0
Protein folding R-HSA-391251 4.169494e-03 2.380 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.458643e-03 2.351 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 4.458643e-03 2.351 0 0
Cell-extracellular matrix interactions R-HSA-446353 4.607184e-03 2.337 0 0
Myogenesis R-HSA-525793 4.692758e-03 2.329 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 4.753542e-03 2.323 0 0
G2/M Transition R-HSA-69275 5.026230e-03 2.299 0 0
Macroautophagy R-HSA-1632852 5.052724e-03 2.296 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 5.157661e-03 2.288 0 0
Post NMDA receptor activation events R-HSA-438064 5.333269e-03 2.273 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 5.409070e-03 2.267 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 5.939711e-03 2.226 0 0
Cytokine Signaling in Immune system R-HSA-1280215 6.095831e-03 2.215 1 0
Signaling by EGFR R-HSA-177929 6.175899e-03 2.209 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 6.203468e-03 2.207 0 0
Death Receptor Signaling R-HSA-73887 6.978663e-03 2.156 1 0
Activation of RAC1 R-HSA-428540 7.562018e-03 2.121 0 0
MTOR signalling R-HSA-165159 7.778550e-03 2.109 0 0
MET interacts with TNS proteins R-HSA-8875513 7.809600e-03 2.107 0 0
ISG15 antiviral mechanism R-HSA-1169408 7.953046e-03 2.099 0 0
Metabolism of non-coding RNA R-HSA-194441 8.669204e-03 2.062 0 0
snRNP Assembly R-HSA-191859 8.669204e-03 2.062 0 0
Repression of WNT target genes R-HSA-4641265 9.794679e-03 2.009 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 9.794679e-03 2.009 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 9.177545e-03 2.037 0 0
Signaling by Hippo R-HSA-2028269 9.115813e-03 2.040 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 9.794679e-03 2.009 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 9.819632e-03 2.008 0 0
G alpha (12/13) signalling events R-HSA-416482 1.057169e-02 1.976 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.097748e-02 1.959 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.132273e-02 1.946 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.140066e-02 1.943 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 1.273154e-02 1.895 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 1.273154e-02 1.895 0 0
Type I hemidesmosome assembly R-HSA-446107 1.226008e-02 1.912 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 1.226008e-02 1.912 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 1.244254e-02 1.905 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.244254e-02 1.905 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.244254e-02 1.905 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.274060e-02 1.895 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.274060e-02 1.895 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.274060e-02 1.895 0 0
Signaling by RAS mutants R-HSA-6802949 1.274060e-02 1.895 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.244254e-02 1.905 0 0
tRNA processing in the nucleus R-HSA-6784531 1.188557e-02 1.925 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 1.226008e-02 1.912 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.274060e-02 1.895 0 0
Signaling by ALK R-HSA-201556 1.277837e-02 1.894 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.285826e-02 1.891 0 0
TGFBR3 expression R-HSA-9839394 1.322571e-02 1.879 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.379106e-02 1.860 0 0
Autophagy R-HSA-9612973 1.450929e-02 1.838 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 1.545493e-02 1.811 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 1.545493e-02 1.811 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.553702e-02 1.809 0 0
NGF-stimulated transcription R-HSA-9031628 1.597151e-02 1.797 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.632921e-02 1.787 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.632921e-02 1.787 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.635314e-02 1.786 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.907828e-02 1.719 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.839231e-02 1.735 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 1.912700e-02 1.718 0 0
MAP2K and MAPK activation R-HSA-5674135 1.839231e-02 1.735 0 0
HATs acetylate histones R-HSA-3214847 1.734064e-02 1.761 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.793873e-02 1.746 0 0
Late Phase of HIV Life Cycle R-HSA-162599 2.015308e-02 1.696 0 0
Apoptosis R-HSA-109581 2.048956e-02 1.688 1 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 2.069052e-02 1.684 0 0
Clathrin-mediated endocytosis R-HSA-8856828 2.137395e-02 1.670 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 2.155431e-02 1.666 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 2.247840e-02 1.648 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 2.344457e-02 1.630 0 0
Deubiquitination R-HSA-5688426 2.403499e-02 1.619 0 0
Axon guidance R-HSA-422475 2.421667e-02 1.616 0 0
Breakdown of the nuclear lamina R-HSA-352238 2.434904e-02 1.614 0 0
Viral Messenger RNA Synthesis R-HSA-168325 2.478570e-02 1.606 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.493518e-02 1.603 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.529365e-02 1.597 0 0
Smooth Muscle Contraction R-HSA-445355 2.666032e-02 1.574 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.683660e-02 1.571 0 0
HIV Life Cycle R-HSA-162587 2.686599e-02 1.571 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 2.688093e-02 1.571 0 0
Nervous system development R-HSA-9675108 2.701946e-02 1.568 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 2.776703e-02 1.556 0 0
Deadenylation of mRNA R-HSA-429947 3.483245e-02 1.458 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.435859e-02 1.464 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 3.150648e-02 1.502 0 0
Cilium Assembly R-HSA-5617833 3.213459e-02 1.493 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 3.329419e-02 1.478 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 3.031761e-02 1.518 0 0
Neurodegenerative Diseases R-HSA-8863678 3.483245e-02 1.458 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 3.483245e-02 1.458 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.613630e-02 1.442 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.793105e-02 1.421 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.802803e-02 1.420 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.802803e-02 1.420 0 0
Intraflagellar transport R-HSA-5620924 3.808028e-02 1.419 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 3.858080e-02 1.414 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.865355e-02 1.413 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 3.888052e-02 1.410 0 0
Cell junction organization R-HSA-446728 3.969089e-02 1.401 0 0
Developmental Biology R-HSA-1266738 3.971519e-02 1.401 0 0
HDMs demethylate histones R-HSA-3214842 3.975901e-02 1.401 0 0
UCH proteinases R-HSA-5689603 4.004574e-02 1.397 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 4.044301e-02 1.393 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 4.044301e-02 1.393 0 0
Interleukin-15 signaling R-HSA-8983432 4.044301e-02 1.393 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 4.681358e-02 1.330 0 0
SOS-mediated signalling R-HSA-112412 4.681358e-02 1.330 0 0
Formation of axial mesoderm R-HSA-9796292 4.851867e-02 1.314 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 4.347339e-02 1.362 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 4.434568e-02 1.353 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 4.452342e-02 1.351 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 4.626593e-02 1.335 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 4.681358e-02 1.330 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 4.510597e-02 1.346 0 0
Estrogen-dependent gene expression R-HSA-9018519 4.147276e-02 1.382 0 0
Gene expression (Transcription) R-HSA-74160 4.605104e-02 1.337 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.077581e-02 1.390 1 1
HCMV Infection R-HSA-9609646 4.629012e-02 1.335 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 4.110408e-02 1.386 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 4.851867e-02 1.314 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.095885e-02 1.388 0 0
Signaling by NTRKs R-HSA-166520 4.792930e-02 1.319 0 0
Cell-Cell communication R-HSA-1500931 4.856835e-02 1.314 0 0
Inositol phosphate metabolism R-HSA-1483249 4.379277e-02 1.359 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 5.020764e-02 1.299 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 5.164370e-02 1.287 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 5.164370e-02 1.287 0 0
MHC class II antigen presentation R-HSA-2132295 5.181891e-02 1.286 0 0
mRNA 3'-end processing R-HSA-72187 5.414946e-02 1.266 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 5.586028e-02 1.253 0 0
Heme signaling R-HSA-9707616 5.724018e-02 1.242 0 0
Regulation of KIT signaling R-HSA-1433559 5.741727e-02 1.241 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 5.863298e-02 1.232 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 5.876382e-02 1.231 0 0
Formation of annular gap junctions R-HSA-196025 5.886009e-02 1.230 0 0
Adrenoceptors R-HSA-390696 5.886009e-02 1.230 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 5.886009e-02 1.230 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 5.928816e-02 1.227 0 0
HSF1 activation R-HSA-3371511 5.928816e-02 1.227 0 0
RNA Polymerase III Transcription R-HSA-74158 5.928816e-02 1.227 0 0
FLT3 signaling in disease R-HSA-9682385 5.928816e-02 1.227 0 0
RUNX2 regulates bone development R-HSA-8941326 5.928816e-02 1.227 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 5.931978e-02 1.227 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 5.931978e-02 1.227 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 5.931978e-02 1.227 0 0
Cyclin D associated events in G1 R-HSA-69231 5.959557e-02 1.225 0 0
G1 Phase R-HSA-69236 5.959557e-02 1.225 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 5.959557e-02 1.225 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 6.100819e-02 1.215 0 0
mRNA Splicing R-HSA-72172 6.159557e-02 1.210 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 7.652815e-02 1.116 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 7.652815e-02 1.116 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 7.652815e-02 1.116 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 7.652815e-02 1.116 0 0
Gap junction degradation R-HSA-190873 7.220615e-02 1.141 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 7.762915e-02 1.110 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 7.762915e-02 1.110 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 7.762915e-02 1.110 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 6.372597e-02 1.196 0 0
MET promotes cell motility R-HSA-8875878 7.156511e-02 1.145 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.080102e-02 1.150 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 7.080102e-02 1.150 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 6.496856e-02 1.187 0 0
Activation of BH3-only proteins R-HSA-114452 7.080102e-02 1.150 1 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 7.551577e-02 1.122 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 6.792347e-02 1.168 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 6.881630e-02 1.162 0 0
Mitotic Spindle Checkpoint R-HSA-69618 6.526236e-02 1.185 0 0
Signaling by NOTCH3 R-HSA-9012852 6.873057e-02 1.163 0 0
Signaling by NOTCH1 R-HSA-1980143 7.729249e-02 1.112 0 0
Unwinding of DNA R-HSA-176974 7.220615e-02 1.141 0 0
Metabolism of RNA R-HSA-8953854 6.490357e-02 1.188 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 6.712698e-02 1.173 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 6.579098e-02 1.182 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 7.251163e-02 1.140 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 7.762915e-02 1.110 0 0
Signaling by TGFBR3 R-HSA-9839373 7.063227e-02 1.151 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 7.408675e-02 1.130 0 0
Interleukin-37 signaling R-HSA-9008059 7.080102e-02 1.150 0 0
S Phase R-HSA-69242 7.768808e-02 1.110 0 0
PTEN Regulation R-HSA-6807070 7.946770e-02 1.100 0 0
Regulation of CDH1 Function R-HSA-9764561 7.969298e-02 1.099 0 0
Regulation of gap junction activity R-HSA-191650 8.348204e-02 1.078 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 8.348204e-02 1.078 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 8.348204e-02 1.078 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 8.348204e-02 1.078 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 8.348204e-02 1.078 0 0
DNA strand elongation R-HSA-69190 8.624835e-02 1.064 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 8.676931e-02 1.062 0 0
Signal attenuation R-HSA-74749 8.676931e-02 1.062 0 0
Signaling by Leptin R-HSA-2586552 8.676931e-02 1.062 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 8.695532e-02 1.061 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 8.889907e-02 1.051 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 8.889907e-02 1.051 0 0
Circadian clock R-HSA-9909396 8.893731e-02 1.051 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 8.937470e-02 1.049 0 0
Nucleotide Excision Repair R-HSA-5696398 9.004593e-02 1.046 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.133484e-02 1.039 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 9.165650e-02 1.038 0 0
Regulation of beta-cell development R-HSA-186712 9.165650e-02 1.038 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 9.259868e-02 1.033 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 9.259868e-02 1.033 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 9.422930e-02 1.026 0 0
Integrin signaling R-HSA-354192 9.461211e-02 1.024 0 0
Nuclear RNA decay R-HSA-9930044 9.461211e-02 1.024 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 9.461211e-02 1.024 0 0
Programmed Cell Death R-HSA-5357801 9.580875e-02 1.019 1 0
HIV Infection R-HSA-162906 9.616049e-02 1.017 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 9.801269e-02 1.009 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 1.080164e-01 0.967 0 0
IRS activation R-HSA-74713 1.080164e-01 0.967 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 1.080164e-01 0.967 0 0
G2 Phase R-HSA-68911 1.080164e-01 0.967 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.341648e-01 0.872 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 1.191737e-01 0.924 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 1.191737e-01 0.924 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.262508e-01 0.899 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.262508e-01 0.899 0 0
Striated Muscle Contraction R-HSA-390522 1.033939e-01 0.986 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.083408e-01 0.965 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 1.321532e-01 0.879 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.107232e-01 0.956 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 1.184061e-01 0.927 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.185597e-01 0.926 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.185597e-01 0.926 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 1.150730e-01 0.939 0 0
Ephrin signaling R-HSA-3928664 1.136175e-01 0.945 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.225129e-01 0.912 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.029062e-01 0.988 0 0
Polo-like kinase mediated events R-HSA-156711 1.136175e-01 0.945 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 1.136175e-01 0.945 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.115359e-01 0.953 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.231819e-01 0.909 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.191737e-01 0.924 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.047577e-01 0.980 0 0
Regulation of TP53 Activity R-HSA-5633007 1.258320e-01 0.900 0 0
Adipogenesis R-HSA-9843745 1.338846e-01 0.873 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.111260e-01 0.954 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 1.033939e-01 0.986 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.046168e-01 0.980 0 0
Cell Cycle Checkpoints R-HSA-69620 1.265857e-01 0.898 0 0
Oncogene Induced Senescence R-HSA-2559585 1.221755e-01 0.913 0 0
Vesicle-mediated transport R-HSA-5653656 1.163196e-01 0.934 0 0
Cellular responses to stress R-HSA-2262752 1.115381e-01 0.953 1 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.341648e-01 0.872 0 0
Mitochondrial biogenesis R-HSA-1592230 1.068482e-01 0.971 0 0
RET signaling R-HSA-8853659 1.321532e-01 0.879 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.136175e-01 0.945 0 0
Adherens junctions interactions R-HSA-418990 1.028107e-01 0.988 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.007685e-01 0.997 0 0
Specification of primordial germ cells R-HSA-9827857 1.009067e-01 0.996 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.136175e-01 0.945 0 0
HDACs deacetylate histones R-HSA-3214815 1.345957e-01 0.871 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.357267e-01 0.867 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.357267e-01 0.867 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 1.368151e-01 0.864 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.368151e-01 0.864 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.368151e-01 0.864 0 0
Signaling by LTK R-HSA-9842663 1.368151e-01 0.864 0 0
HIV elongation arrest and recovery R-HSA-167287 1.379053e-01 0.860 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.379053e-01 0.860 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.412632e-01 0.850 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.425053e-01 0.846 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.428637e-01 0.845 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 1.430909e-01 0.844 0 0
Host Interactions of HIV factors R-HSA-162909 1.440363e-01 0.842 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.472040e-01 0.832 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 1.472040e-01 0.832 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.472040e-01 0.832 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.472040e-01 0.832 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.472040e-01 0.832 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.472040e-01 0.832 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.472040e-01 0.832 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.472040e-01 0.832 0 0
Regulation of gene expression in beta cells R-HSA-210745 1.500133e-01 0.824 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.551432e-01 0.809 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 1.552786e-01 0.809 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 1.555694e-01 0.808 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 1.558252e-01 0.807 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 1.558252e-01 0.807 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 1.558252e-01 0.807 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 1.615370e-01 0.792 0 0
Sensory processing of sound R-HSA-9659379 1.615505e-01 0.792 0 0
Activation of the pre-replicative complex R-HSA-68962 1.625503e-01 0.789 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.633046e-01 0.787 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.660070e-01 0.780 0 0
Signaling by MET R-HSA-6806834 1.695471e-01 0.771 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.706800e-01 0.768 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.706800e-01 0.768 0 0
FOXO-mediated transcription R-HSA-9614085 1.734011e-01 0.761 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.124747e-01 0.673 0 0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) R-HSA-5619111 2.124747e-01 0.673 0 0
Defective VWF binding to collagen type I R-HSA-9845622 2.124747e-01 0.673 0 0
Defective MMADHC causes MMAHCD R-HSA-3359473 2.124747e-01 0.673 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.124747e-01 0.673 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 2.727533e-01 0.564 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 2.727533e-01 0.564 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 2.727533e-01 0.564 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 2.727533e-01 0.564 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 2.727533e-01 0.564 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 2.727533e-01 0.564 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 2.727533e-01 0.564 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 2.727533e-01 0.564 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 2.727533e-01 0.564 0 0
Enhanced cleavage of VWF variant by ADAMTS13 R-HSA-9845619 2.727533e-01 0.564 0 0
Defective VWF cleavage by ADAMTS13 variant R-HSA-9845621 2.727533e-01 0.564 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 2.727533e-01 0.564 0 0
Glycogen storage disease type IV (GBE1) R-HSA-3878781 2.727533e-01 0.564 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 2.727533e-01 0.564 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 2.727533e-01 0.564 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 2.727533e-01 0.564 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 2.727533e-01 0.564 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 2.727533e-01 0.564 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 1.897928e-01 0.722 0 0
IFNG signaling activates MAPKs R-HSA-9732724 1.897928e-01 0.722 0 0
Recycling of eIF2:GDP R-HSA-72731 1.897928e-01 0.722 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.897928e-01 0.722 0 0
Defective MMACHC causes MAHCC R-HSA-3359474 3.284214e-01 0.484 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 3.284214e-01 0.484 1 1
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.284214e-01 0.484 0 0
MET activates PTPN11 R-HSA-8865999 3.284214e-01 0.484 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.284214e-01 0.484 0 0
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023 3.284214e-01 0.484 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 2.186372e-01 0.660 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 2.186372e-01 0.660 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 2.478147e-01 0.606 0 0
HCN channels R-HSA-1296061 3.798314e-01 0.420 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 3.798314e-01 0.420 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 3.798314e-01 0.420 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 3.798314e-01 0.420 0 0
Erythropoietin activates RAS R-HSA-9027284 1.942595e-01 0.712 0 0
Processive synthesis on the lagging strand R-HSA-69183 1.942595e-01 0.712 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.942595e-01 0.712 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.942595e-01 0.712 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 2.771057e-01 0.557 0 0
Phosphorylation of the APC/C R-HSA-176412 2.145752e-01 0.668 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 1.862762e-01 0.730 0 0
Notch-HLH transcription pathway R-HSA-350054 1.862762e-01 0.730 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 4.273088e-01 0.369 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 4.273088e-01 0.369 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 4.273088e-01 0.369 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 4.273088e-01 0.369 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 4.273088e-01 0.369 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.023097e-01 0.694 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.563775e-01 0.591 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 3.353036e-01 0.475 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 3.353036e-01 0.475 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.991510e-01 0.524 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.991510e-01 0.524 0 0
MET activates RAS signaling R-HSA-8851805 3.639154e-01 0.439 0 0
Leading Strand Synthesis R-HSA-69109 3.639154e-01 0.439 0 0
Polymerase switching R-HSA-69091 3.639154e-01 0.439 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 4.711541e-01 0.327 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 4.711541e-01 0.327 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 4.711541e-01 0.327 0 0
Signaling by RNF43 mutants R-HSA-5340588 4.711541e-01 0.327 0 0
Signaling by MAPK mutants R-HSA-9652817 4.711541e-01 0.327 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 4.711541e-01 0.327 0 0
RAF activation R-HSA-5673000 2.307245e-01 0.637 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 2.307245e-01 0.637 0 0
Interaction between L1 and Ankyrins R-HSA-445095 2.698474e-01 0.569 0 0
Negative regulation of MET activity R-HSA-6807004 3.206994e-01 0.494 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 3.920444e-01 0.407 0 0
G1/S-Specific Transcription R-HSA-69205 2.600197e-01 0.585 0 0
Lagging Strand Synthesis R-HSA-69186 3.422578e-01 0.466 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 3.422578e-01 0.466 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.018980e-01 0.695 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 2.629877e-01 0.580 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 3.227546e-01 0.491 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 3.227546e-01 0.491 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 3.637601e-01 0.439 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 3.637601e-01 0.439 0 0
Removal of the Flap Intermediate R-HSA-69166 4.195968e-01 0.377 0 0
Retrograde neurotrophin signalling R-HSA-177504 4.195968e-01 0.377 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 5.116450e-01 0.291 0 0
Signaling by LTK in cancer R-HSA-9842640 5.116450e-01 0.291 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 5.116450e-01 0.291 0 0
STAT5 Activation R-HSA-9645135 5.116450e-01 0.291 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.116450e-01 0.291 0 0
Centrosome maturation R-HSA-380287 2.209572e-01 0.656 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.207880e-01 0.494 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 2.756504e-01 0.560 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 4.464962e-01 0.350 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 4.464962e-01 0.350 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 3.588052e-01 0.445 0 0
Translation initiation complex formation R-HSA-72649 3.727846e-01 0.429 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 4.981033e-01 0.303 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.007718e-01 0.397 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 4.007718e-01 0.397 0 0
MET activates PTK2 signaling R-HSA-8874081 4.684759e-01 0.329 0 0
Nuclear Receptor transcription pathway R-HSA-383280 3.783917e-01 0.422 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.885408e-01 0.311 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 4.601156e-01 0.337 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 5.082285e-01 0.294 0 0
Formation of the Early Elongation Complex R-HSA-113418 5.082285e-01 0.294 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 5.147581e-01 0.288 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 5.147581e-01 0.288 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 4.906291e-01 0.309 0 0
Transcription of the HIV genome R-HSA-167172 2.626962e-01 0.581 0 0
HIV Transcription Elongation R-HSA-167169 3.207880e-01 0.494 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 4.274327e-01 0.369 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 4.259429e-01 0.371 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 2.563775e-01 0.591 0 0
G0 and Early G1 R-HSA-1538133 1.888062e-01 0.724 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.207880e-01 0.494 0 0
Developmental Cell Lineages R-HSA-9734767 3.275383e-01 0.485 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 4.195968e-01 0.377 0 0
Signaling by ERBB2 R-HSA-1227986 1.795775e-01 0.746 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 4.641521e-01 0.333 0 0
G1/S Transition R-HSA-69206 3.269384e-01 0.486 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 2.478147e-01 0.606 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 3.851451e-01 0.414 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 1.897928e-01 0.722 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 2.478147e-01 0.606 1 1
PI3K/AKT activation R-HSA-198203 2.771057e-01 0.557 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 3.353036e-01 0.475 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.053964e-01 0.515 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 3.851451e-01 0.414 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 3.207880e-01 0.494 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 4.885408e-01 0.311 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.307245e-01 0.637 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.763186e-01 0.559 0 0
Synthesis of DNA R-HSA-69239 3.512071e-01 0.454 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.354942e-01 0.628 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.637601e-01 0.439 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.776847e-01 0.556 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.991510e-01 0.524 0 0
Regulation of IFNG signaling R-HSA-877312 3.639154e-01 0.439 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 3.639154e-01 0.439 0 0
VLDLR internalisation and degradation R-HSA-8866427 3.639154e-01 0.439 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.878932e-01 0.541 1 1
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 1.862762e-01 0.730 0 0
Interleukin-2 signaling R-HSA-9020558 3.063220e-01 0.514 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 4.684759e-01 0.329 0 0
DCC mediated attractive signaling R-HSA-418885 1.942595e-01 0.712 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 2.353119e-01 0.628 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 4.273088e-01 0.369 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.273088e-01 0.369 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 2.563775e-01 0.591 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 2.116019e-01 0.674 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 3.422578e-01 0.466 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 4.752572e-01 0.323 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 4.752572e-01 0.323 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.776847e-01 0.556 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 3.920444e-01 0.407 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.795775e-01 0.746 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.795775e-01 0.746 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.795775e-01 0.746 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.795775e-01 0.746 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 4.425624e-01 0.354 0 0
DNA Double Strand Break Response R-HSA-5693606 3.890180e-01 0.410 1 0
MET Receptor Activation R-HSA-6806942 5.116450e-01 0.291 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 4.726811e-01 0.325 0 0
Switching of origins to a post-replicative state R-HSA-69052 3.195399e-01 0.495 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 4.885408e-01 0.311 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 5.227261e-01 0.282 0 0
Signaling by SCF-KIT R-HSA-1433557 2.241171e-01 0.650 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.518025e-01 0.454 0 0
RNA Polymerase II Transcription R-HSA-73857 2.917094e-01 0.535 0 0
Interleukin-2 family signaling R-HSA-451927 1.756584e-01 0.755 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 3.353036e-01 0.475 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 3.206994e-01 0.494 0 0
EPH-Ephrin signaling R-HSA-2682334 1.956388e-01 0.709 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.684759e-01 0.329 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 4.731616e-01 0.325 0 0
Generic Transcription Pathway R-HSA-212436 5.223815e-01 0.282 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 2.478147e-01 0.606 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.923134e-01 0.534 1 0
Signaling by NOTCH4 R-HSA-9013694 2.113413e-01 0.675 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 4.274327e-01 0.369 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.353119e-01 0.628 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 2.187319e-01 0.660 0 0
Mismatch Repair R-HSA-5358508 2.776847e-01 0.556 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 4.528961e-01 0.344 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 3.053964e-01 0.515 0 0
Signaling by VEGF R-HSA-194138 2.316088e-01 0.635 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.124747e-01 0.673 0 0
mRNA Editing: A to I Conversion R-HSA-75064 2.727533e-01 0.564 0 0
Signalling to ERK5 R-HSA-198765 2.727533e-01 0.564 0 0
C6 deamination of adenosine R-HSA-75102 2.727533e-01 0.564 0 0
MET activates STAT3 R-HSA-8875791 3.284214e-01 0.484 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 3.284214e-01 0.484 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 2.478147e-01 0.606 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 3.798314e-01 0.420 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 3.798314e-01 0.420 0 0
Disorders of Developmental Biology R-HSA-9675151 2.353119e-01 0.628 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 2.353119e-01 0.628 0 0
Bicarbonate transporters R-HSA-425381 3.063220e-01 0.514 0 0
Reelin signalling pathway R-HSA-8866376 4.273088e-01 0.369 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 4.273088e-01 0.369 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 2.187319e-01 0.660 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 3.353036e-01 0.475 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 4.195968e-01 0.377 0 0
G2/M DNA replication checkpoint R-HSA-69478 5.116450e-01 0.291 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 2.763186e-01 0.559 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 4.464962e-01 0.350 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 4.063572e-01 0.391 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 4.273458e-01 0.369 0 0
Signaling by NOTCH2 R-HSA-1980145 4.117958e-01 0.385 0 0
Glycogen storage diseases R-HSA-3229121 5.227261e-01 0.282 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 5.147581e-01 0.288 0 0
Orc1 removal from chromatin R-HSA-68949 5.197658e-01 0.284 0 0
Signaling by NOTCH R-HSA-157118 3.339796e-01 0.476 0 0
Signaling by FGFR1 in disease R-HSA-5655302 3.518025e-01 0.454 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.762815e-01 0.424 0 0
Neurexins and neuroligins R-HSA-6794361 3.448596e-01 0.462 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 3.122285e-01 0.506 0 0
ESR-mediated signaling R-HSA-8939211 3.145609e-01 0.502 0 0
Formation of definitive endoderm R-HSA-9823730 3.206994e-01 0.494 0 0
Rab regulation of trafficking R-HSA-9007101 3.526651e-01 0.453 0 0
EGFR downregulation R-HSA-182971 1.754903e-01 0.756 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.921971e-01 0.716 0 0
DNA Repair R-HSA-73894 3.985526e-01 0.400 1 0
Receptor Mediated Mitophagy R-HSA-8934903 2.771057e-01 0.557 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 2.353119e-01 0.628 0 0
Rap1 signalling R-HSA-392517 2.991510e-01 0.524 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.195968e-01 0.377 1 1
Acetylcholine regulates insulin secretion R-HSA-399997 4.981033e-01 0.303 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 5.227261e-01 0.282 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.926352e-01 0.715 0 0
Prolonged ERK activation events R-HSA-169893 4.726811e-01 0.325 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.746825e-01 0.758 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.405821e-01 0.468 0 0
Regulation of TNFR1 signaling R-HSA-5357905 2.629877e-01 0.580 0 0
Semaphorin interactions R-HSA-373755 3.379484e-01 0.471 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.002596e-01 0.523 0 0
Formation of intermediate mesoderm R-HSA-9761174 2.771057e-01 0.557 0 0
Pervasive developmental disorders R-HSA-9005895 3.639154e-01 0.439 0 0
Disorders of Nervous System Development R-HSA-9697154 3.639154e-01 0.439 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 3.639154e-01 0.439 0 0
Homology Directed Repair R-HSA-5693538 4.806140e-01 0.318 0 0
MAPK family signaling cascades R-HSA-5683057 3.943726e-01 0.404 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 4.837413e-01 0.315 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.368665e-01 0.625 0 0
TNF signaling R-HSA-75893 4.007718e-01 0.397 0 0
Cellular responses to stimuli R-HSA-8953897 3.033172e-01 0.518 1 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 3.049948e-01 0.516 1 0
Downstream signal transduction R-HSA-186763 3.405821e-01 0.468 0 0
Acyl chain remodelling of PS R-HSA-1482801 4.480656e-01 0.349 0 0
Signalling to ERKs R-HSA-187687 4.293998e-01 0.367 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.006529e-01 0.522 0 0
Signaling by KIT in disease R-HSA-9669938 3.851451e-01 0.414 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 3.284214e-01 0.484 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 2.771057e-01 0.557 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 2.353119e-01 0.628 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.711541e-01 0.327 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.795775e-01 0.746 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 2.749834e-01 0.561 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 4.063572e-01 0.391 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.762815e-01 0.424 0 0
Killing mechanisms R-HSA-9664420 4.726811e-01 0.325 1 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 4.726811e-01 0.325 1 1
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.620793e-01 0.441 0 0
Protein-protein interactions at synapses R-HSA-6794362 4.614233e-01 0.336 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 3.246530e-01 0.489 0 0
Netrin-1 signaling R-HSA-373752 3.985071e-01 0.400 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.515965e-01 0.599 1 0
STING mediated induction of host immune responses R-HSA-1834941 2.991510e-01 0.524 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.637601e-01 0.439 0 0
FLT3 Signaling R-HSA-9607240 3.362658e-01 0.473 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 5.147581e-01 0.288 0 0
Generation of second messenger molecules R-HSA-202433 5.147581e-01 0.288 0 0
Suppression of apoptosis R-HSA-9635465 3.063220e-01 0.514 0 0
TBC/RABGAPs R-HSA-8854214 3.829482e-01 0.417 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 2.364144e-01 0.626 0 0
MAP kinase activation R-HSA-450294 4.701077e-01 0.328 1 0
Cell-cell junction organization R-HSA-421270 2.558815e-01 0.592 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 4.684759e-01 0.329 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 4.020264e-01 0.396 0 0
Gastrulation R-HSA-9758941 2.622645e-01 0.581 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 3.851451e-01 0.414 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 3.908761e-01 0.408 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.116019e-01 0.674 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 1.897928e-01 0.722 0 0
The NLRP1 inflammasome R-HSA-844455 3.284214e-01 0.484 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 2.478147e-01 0.606 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 4.711541e-01 0.327 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 3.920444e-01 0.407 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.053964e-01 0.515 0 0
Hedgehog 'off' state R-HSA-5610787 1.807686e-01 0.743 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 4.464962e-01 0.350 0 0
Differentiation of T cells R-HSA-9945266 4.726811e-01 0.325 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 4.726811e-01 0.325 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 3.715295e-01 0.430 0 0
Diseases of programmed cell death R-HSA-9645723 3.686512e-01 0.433 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.596299e-01 0.444 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 3.980320e-01 0.400 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 4.480656e-01 0.349 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 4.684759e-01 0.329 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 5.227261e-01 0.282 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 2.478147e-01 0.606 0 0
Signaling by PTK6 R-HSA-8848021 4.972643e-01 0.303 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 4.972643e-01 0.303 0 0
Uptake and function of anthrax toxins R-HSA-5210891 2.563775e-01 0.591 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 3.422578e-01 0.466 0 0
Signal regulatory protein family interactions R-HSA-391160 4.195968e-01 0.377 0 0
Nef and signal transduction R-HSA-164944 5.116450e-01 0.291 0 0
Signaling by TGFB family members R-HSA-9006936 3.471926e-01 0.459 0 0
Signaling by Hedgehog R-HSA-5358351 4.630379e-01 0.334 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.140252e-01 0.383 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 3.762815e-01 0.424 0 0
Signaling by Interleukins R-HSA-449147 1.921893e-01 0.716 1 0
Josephin domain DUBs R-HSA-5689877 2.771057e-01 0.557 0 0
CD28 dependent Vav1 pathway R-HSA-389359 3.920444e-01 0.407 0 0
tRNA processing R-HSA-72306 4.367275e-01 0.360 0 0
ChREBP activates metabolic gene expression R-HSA-163765 3.063220e-01 0.514 0 0
PECAM1 interactions R-HSA-210990 3.063220e-01 0.514 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 4.273088e-01 0.369 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 4.711541e-01 0.327 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 5.116450e-01 0.291 0 0
Neurofascin interactions R-HSA-447043 5.116450e-01 0.291 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 4.464962e-01 0.350 0 0
OAS antiviral response R-HSA-8983711 3.639154e-01 0.439 0 0
Glycolysis R-HSA-70171 2.743972e-01 0.562 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 4.981033e-01 0.303 0 0
Gene Silencing by RNA R-HSA-211000 3.512071e-01 0.454 0 0
Glucose metabolism R-HSA-70326 4.707182e-01 0.327 0 0
Interleukin-7 signaling R-HSA-1266695 4.480656e-01 0.349 0 0
Growth hormone receptor signaling R-HSA-982772 4.063572e-01 0.391 0 0
Cellular response to hypoxia R-HSA-1234174 5.239281e-01 0.281 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 5.239281e-01 0.281 0 0
Signaling by Erythropoietin R-HSA-9006335 5.275118e-01 0.278 0 0
Late endosomal microautophagy R-HSA-9615710 5.275118e-01 0.278 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 5.275118e-01 0.278 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 5.342448e-01 0.272 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 5.463671e-01 0.263 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 5.463671e-01 0.263 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 5.463671e-01 0.263 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 5.465230e-01 0.262 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 5.465230e-01 0.262 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 5.465230e-01 0.262 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 5.465230e-01 0.262 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 5.465230e-01 0.262 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 5.465230e-01 0.262 0 0
Tie2 Signaling R-HSA-210993 5.465230e-01 0.262 0 0
Nephron development R-HSA-9831926 5.465230e-01 0.262 0 0
GAB1 signalosome R-HSA-180292 5.465230e-01 0.262 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 5.472305e-01 0.262 0 0
HIV Transcription Initiation R-HSA-167161 5.472305e-01 0.262 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 5.472305e-01 0.262 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 5.490380e-01 0.260 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 5.490380e-01 0.260 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 5.490380e-01 0.260 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 5.490380e-01 0.260 0 0
Disinhibition of SNARE formation R-HSA-114516 5.490380e-01 0.260 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.490380e-01 0.260 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 5.490380e-01 0.260 0 0
PTK6 Expression R-HSA-8849473 5.490380e-01 0.260 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 5.490380e-01 0.260 0 0
VLDL clearance R-HSA-8964046 5.490380e-01 0.260 0 0
Regulation of PTEN localization R-HSA-8948747 5.490380e-01 0.260 0 0
Netrin mediated repulsion signals R-HSA-418886 5.490380e-01 0.260 0 0
CHL1 interactions R-HSA-447041 5.490380e-01 0.260 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.515781e-01 0.258 0 0
Signaling by WNT R-HSA-195721 5.526488e-01 0.258 0 0
Trafficking of AMPA receptors R-HSA-399719 5.647745e-01 0.248 0 0
Regulation of signaling by CBL R-HSA-912631 5.694760e-01 0.245 0 0
Assembly of the pre-replicative complex R-HSA-68867 5.751258e-01 0.240 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 5.754602e-01 0.240 0 0
Activation of HOX genes during differentiation R-HSA-5619507 5.754602e-01 0.240 0 0
RSV-host interactions R-HSA-9833110 5.754602e-01 0.240 0 0
Muscle contraction R-HSA-397014 5.756692e-01 0.240 0 0
G2/M Checkpoints R-HSA-69481 5.766425e-01 0.239 0 0
Potential therapeutics for SARS R-HSA-9679191 5.782240e-01 0.238 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 5.785323e-01 0.238 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 5.827177e-01 0.235 0 0
Signaling by WNT in cancer R-HSA-4791275 5.827177e-01 0.235 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 5.827177e-01 0.235 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 5.835699e-01 0.234 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 5.835699e-01 0.234 0 0
MET receptor recycling R-HSA-8875656 5.835699e-01 0.234 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 5.835699e-01 0.234 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 5.835699e-01 0.234 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 5.835699e-01 0.234 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 5.835699e-01 0.234 0 0
TGFBR3 PTM regulation R-HSA-9839383 5.835699e-01 0.234 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 5.835699e-01 0.234 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 5.835699e-01 0.234 0 0
Sodium/Proton exchangers R-HSA-425986 5.835699e-01 0.234 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 5.835699e-01 0.234 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 5.835699e-01 0.234 0 0
Interleukin-17 signaling R-HSA-448424 5.878543e-01 0.231 1 0
Glycogen synthesis R-HSA-3322077 5.915749e-01 0.228 0 0
Co-inhibition by CTLA4 R-HSA-389513 5.915749e-01 0.228 0 0
Protein hydroxylation R-HSA-9629569 5.915749e-01 0.228 0 0
RMTs methylate histone arginines R-HSA-3214858 5.937110e-01 0.226 0 0
Parasite infection R-HSA-9664407 5.949472e-01 0.226 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 5.949472e-01 0.226 0 0
Leishmania phagocytosis R-HSA-9664417 5.949472e-01 0.226 0 0
Signaling by ROBO receptors R-HSA-376176 5.966913e-01 0.224 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.979541e-01 0.223 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 6.000975e-01 0.222 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 6.000975e-01 0.222 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 6.001833e-01 0.222 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 6.001833e-01 0.222 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 6.001833e-01 0.222 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 6.033884e-01 0.219 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 6.085605e-01 0.216 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.128158e-01 0.213 1 1
Signalling to RAS R-HSA-167044 6.128158e-01 0.213 0 0
ERK/MAPK targets R-HSA-198753 6.128158e-01 0.213 0 0
ARMS-mediated activation R-HSA-170984 6.154595e-01 0.211 0 0
Lipophagy R-HSA-9613354 6.154595e-01 0.211 0 0
ALK mutants bind TKIs R-HSA-9700645 6.154595e-01 0.211 0 0
Calcineurin activates NFAT R-HSA-2025928 6.154595e-01 0.211 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 6.154595e-01 0.211 0 0
p75NTR regulates axonogenesis R-HSA-193697 6.154595e-01 0.211 0 0
mRNA Editing R-HSA-75072 6.154595e-01 0.211 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.154595e-01 0.211 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 6.154595e-01 0.211 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 6.154595e-01 0.211 0 0
Regulated proteolysis of p75NTR R-HSA-193692 6.154595e-01 0.211 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 6.154595e-01 0.211 0 0
Cellular response to mitochondrial stress R-HSA-9840373 6.154595e-01 0.211 0 0
Effects of PIP2 hydrolysis R-HSA-114508 6.171611e-01 0.210 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 6.171611e-01 0.210 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 6.198156e-01 0.208 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 6.230721e-01 0.205 0 0
Ca2+ pathway R-HSA-4086398 6.239824e-01 0.205 0 0
DNA Replication Pre-Initiation R-HSA-69002 6.251380e-01 0.204 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 6.293466e-01 0.201 0 0
Dual Incision in GG-NER R-HSA-5696400 6.336435e-01 0.198 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 6.336435e-01 0.198 0 0
Mitophagy R-HSA-5205647 6.336435e-01 0.198 0 0
G2/M DNA damage checkpoint R-HSA-69473 6.356124e-01 0.197 0 0
Signaling by FGFR in disease R-HSA-1226099 6.356124e-01 0.197 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 6.372386e-01 0.196 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 6.377542e-01 0.195 1 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 6.377542e-01 0.195 1 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 6.377542e-01 0.195 1 0
Formation of paraxial mesoderm R-HSA-9793380 6.419317e-01 0.193 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 6.449087e-01 0.191 0 0
Folding of actin by CCT/TriC R-HSA-390450 6.449087e-01 0.191 0 0
DNA replication initiation R-HSA-68952 6.449087e-01 0.191 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 6.449087e-01 0.191 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 6.449087e-01 0.191 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 6.449087e-01 0.191 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 6.449087e-01 0.191 0 0
Pexophagy R-HSA-9664873 6.449087e-01 0.191 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 6.449087e-01 0.191 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 6.449087e-01 0.191 0 0
Regulation of CDH11 function R-HSA-9762292 6.449087e-01 0.191 0 0
Regulation of Apoptosis R-HSA-169911 6.496253e-01 0.187 0 0
Co-stimulation by CD28 R-HSA-389356 6.510542e-01 0.186 0 0
FGFR2 alternative splicing R-HSA-6803529 6.527358e-01 0.185 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 6.527358e-01 0.185 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 6.527358e-01 0.185 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 6.527358e-01 0.185 0 0
LDL clearance R-HSA-8964038 6.527358e-01 0.185 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 6.542471e-01 0.184 0 0
Signaling by PDGF R-HSA-186797 6.542471e-01 0.184 0 0
RAF/MAP kinase cascade R-HSA-5673001 6.555892e-01 0.183 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 6.582229e-01 0.182 0 0
Interleukin-12 signaling R-HSA-9020591 6.582229e-01 0.182 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 6.625648e-01 0.179 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 6.662884e-01 0.176 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 6.714320e-01 0.173 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 6.714320e-01 0.173 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 6.714320e-01 0.173 0 0
Syndecan interactions R-HSA-3000170 6.714320e-01 0.173 0 0
Formation of the ureteric bud R-HSA-9830674 6.714320e-01 0.173 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 6.715727e-01 0.173 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 6.721043e-01 0.173 0 0
Signaling by APC mutants R-HSA-4839744 6.721043e-01 0.173 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 6.721043e-01 0.173 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 6.721043e-01 0.173 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 6.721043e-01 0.173 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 6.721043e-01 0.173 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 6.721043e-01 0.173 0 0
vRNA Synthesis R-HSA-192814 6.721043e-01 0.173 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 6.721043e-01 0.173 0 0
Synthesis of PI R-HSA-1483226 6.721043e-01 0.173 0 0
Prostanoid ligand receptors R-HSA-391908 6.721043e-01 0.173 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 6.721146e-01 0.173 0 0
Base Excision Repair R-HSA-73884 6.726860e-01 0.172 0 0
RNA Polymerase I Transcription R-HSA-73864 6.799415e-01 0.168 0 0
Collagen chain trimerization R-HSA-8948216 6.800779e-01 0.167 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 6.805466e-01 0.167 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 6.891525e-01 0.162 1 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 6.893030e-01 0.162 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 6.893030e-01 0.162 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 6.903564e-01 0.161 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 6.945488e-01 0.158 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 6.955859e-01 0.158 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 6.972185e-01 0.157 0 0
Signaling by GSK3beta mutants R-HSA-5339716 6.972185e-01 0.157 0 0
Proton-coupled monocarboxylate transport R-HSA-433692 6.972185e-01 0.157 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 6.972185e-01 0.157 0 0
Plasmalogen biosynthesis R-HSA-75896 6.972185e-01 0.157 0 0
NF-kB is activated and signals survival R-HSA-209560 6.972185e-01 0.157 0 0
Signaling by AMER1 mutants R-HSA-4839748 6.972185e-01 0.157 0 0
Signaling by AXIN mutants R-HSA-4839735 6.972185e-01 0.157 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 6.972185e-01 0.157 0 0
Anchoring fibril formation R-HSA-2214320 6.972185e-01 0.157 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 7.027353e-01 0.153 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 7.027353e-01 0.153 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 7.027353e-01 0.153 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.061385e-01 0.151 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.061385e-01 0.151 0 0
Long-term potentiation R-HSA-9620244 7.063656e-01 0.151 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 7.063656e-01 0.151 0 0
Plasma lipoprotein clearance R-HSA-8964043 7.085192e-01 0.150 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 7.115973e-01 0.148 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 7.116563e-01 0.148 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 7.125651e-01 0.147 1 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 7.147525e-01 0.146 0 0
Meiotic synapsis R-HSA-1221632 7.147525e-01 0.146 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 7.204106e-01 0.142 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 7.204106e-01 0.142 0 0
GRB2 events in EGFR signaling R-HSA-179812 7.204106e-01 0.142 0 0
Scavenging by Class F Receptors R-HSA-3000484 7.204106e-01 0.142 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 7.204106e-01 0.142 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 7.204106e-01 0.142 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 7.204106e-01 0.142 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 7.204106e-01 0.142 0 0
p75NTR recruits signalling complexes R-HSA-209543 7.204106e-01 0.142 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 7.204106e-01 0.142 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 7.204106e-01 0.142 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 7.204106e-01 0.142 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 7.219934e-01 0.141 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 7.219934e-01 0.141 0 0
Glycogen metabolism R-HSA-8982491 7.219934e-01 0.141 0 0
Metalloprotease DUBs R-HSA-5689901 7.226387e-01 0.141 0 0
TRP channels R-HSA-3295583 7.226387e-01 0.141 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 7.264089e-01 0.139 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 7.304792e-01 0.136 1 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 7.304792e-01 0.136 1 0
VEGFR2 mediated vascular permeability R-HSA-5218920 7.349768e-01 0.134 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 7.355694e-01 0.133 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 7.377063e-01 0.132 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 7.378229e-01 0.132 1 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 7.381432e-01 0.132 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 7.381432e-01 0.132 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 7.418275e-01 0.130 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 7.418275e-01 0.130 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 7.418275e-01 0.130 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 7.418275e-01 0.130 0 0
Frs2-mediated activation R-HSA-170968 7.418275e-01 0.130 0 0
Maturation of nucleoprotein R-HSA-9683610 7.418275e-01 0.130 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 7.418275e-01 0.130 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 7.458941e-01 0.127 1 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 7.459369e-01 0.127 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 7.474763e-01 0.126 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 7.486474e-01 0.126 0 0
Interferon gamma signaling R-HSA-877300 7.490090e-01 0.126 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 7.524957e-01 0.123 0 0
Regulation of mitotic cell cycle R-HSA-453276 7.524957e-01 0.123 0 0
Pyrimidine salvage R-HSA-73614 7.529012e-01 0.123 0 0
Inflammasomes R-HSA-622312 7.529012e-01 0.123 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.534334e-01 0.123 1 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.534334e-01 0.123 1 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.537907e-01 0.123 1 0
MyD88-independent TLR4 cascade R-HSA-166166 7.537907e-01 0.123 1 0
Ub-specific processing proteases R-HSA-5689880 7.569131e-01 0.121 0 0
IRS-mediated signalling R-HSA-112399 7.592354e-01 0.120 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 7.616050e-01 0.118 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 7.616050e-01 0.118 0 0
Prolactin receptor signaling R-HSA-1170546 7.616050e-01 0.118 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 7.616050e-01 0.118 0 0
Signaling by FGFR4 in disease R-HSA-5655291 7.616050e-01 0.118 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 7.616050e-01 0.118 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 7.616050e-01 0.118 0 0
SARS-CoV-2-host interactions R-HSA-9705683 7.639407e-01 0.117 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 7.662137e-01 0.116 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 7.669361e-01 0.115 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.669361e-01 0.115 0 0
mRNA Capping R-HSA-72086 7.669361e-01 0.115 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 7.677358e-01 0.115 1 0
Dual incision in TC-NER R-HSA-6782135 7.694743e-01 0.114 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 7.710551e-01 0.113 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 7.743055e-01 0.111 0 0
Interleukin-12 family signaling R-HSA-447115 7.746348e-01 0.111 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 7.764351e-01 0.110 1 0
Extension of Telomeres R-HSA-180786 7.793686e-01 0.108 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 7.798686e-01 0.108 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 7.798686e-01 0.108 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 7.798686e-01 0.108 0 0
Telomere C-strand synthesis initiation R-HSA-174430 7.798686e-01 0.108 0 0
SHC1 events in EGFR signaling R-HSA-180336 7.798686e-01 0.108 0 0
p75NTR signals via NF-kB R-HSA-193639 7.798686e-01 0.108 0 0
p38MAPK events R-HSA-171007 7.798686e-01 0.108 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 7.798686e-01 0.108 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 7.798686e-01 0.108 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 7.798686e-01 0.108 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 7.798686e-01 0.108 0 0
Protein methylation R-HSA-8876725 7.798686e-01 0.108 0 0
Spry regulation of FGF signaling R-HSA-1295596 7.798686e-01 0.108 0 0
Signaling by ERBB4 R-HSA-1236394 7.801808e-01 0.108 0 0
Amine ligand-binding receptors R-HSA-375280 7.821525e-01 0.107 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 7.888602e-01 0.103 0 0
Influenza Infection R-HSA-168255 7.923893e-01 0.101 0 0
DAG and IP3 signaling R-HSA-1489509 7.928018e-01 0.101 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 7.929338e-01 0.101 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 7.929338e-01 0.101 0 0
Budding and maturation of HIV virion R-HSA-162588 7.929338e-01 0.101 0 0
PI Metabolism R-HSA-1483255 7.938356e-01 0.100 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 7.967339e-01 0.099 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 7.967339e-01 0.099 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 7.967339e-01 0.099 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 7.967339e-01 0.099 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 7.967339e-01 0.099 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 7.967339e-01 0.099 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 7.967339e-01 0.099 0 0
Negative regulation of FLT3 R-HSA-9706369 7.967339e-01 0.099 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 7.967339e-01 0.099 0 0
Activation of SMO R-HSA-5635838 7.967339e-01 0.099 0 0
SLC transporter disorders R-HSA-5619102 7.981134e-01 0.098 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 7.981443e-01 0.098 0 0
Collagen degradation R-HSA-1442490 7.981443e-01 0.098 0 0
DNA Replication R-HSA-69306 7.987076e-01 0.098 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 8.030136e-01 0.095 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 8.030136e-01 0.095 0 0
Diseases of DNA repair R-HSA-9675135 8.030136e-01 0.095 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 8.054147e-01 0.094 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 8.070371e-01 0.093 0 0
NCAM signaling for neurite out-growth R-HSA-375165 8.070371e-01 0.093 0 0
PPARA activates gene expression R-HSA-1989781 8.102166e-01 0.091 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 8.123081e-01 0.090 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 8.123081e-01 0.090 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 8.123081e-01 0.090 0 0
Fibronectin matrix formation R-HSA-1566977 8.123081e-01 0.090 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 8.123081e-01 0.090 0 0
tRNA modification in the mitochondrion R-HSA-6787450 8.123081e-01 0.090 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 8.123081e-01 0.090 0 0
PCP/CE pathway R-HSA-4086400 8.132974e-01 0.090 0 0
G-protein beta:gamma signalling R-HSA-397795 8.163347e-01 0.088 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 8.163347e-01 0.088 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 8.163347e-01 0.088 0 0
Signaling by Nuclear Receptors R-HSA-9006931 8.188417e-01 0.087 0 0
HCMV Late Events R-HSA-9610379 8.212307e-01 0.086 0 0
Transmission across Chemical Synapses R-HSA-112315 8.229510e-01 0.085 0 0
Insulin receptor signalling cascade R-HSA-74751 8.238641e-01 0.084 0 0
IGF1R signaling cascade R-HSA-2428924 8.238641e-01 0.084 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 8.266898e-01 0.083 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 8.266898e-01 0.083 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 8.266898e-01 0.083 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 8.266898e-01 0.083 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 8.266898e-01 0.083 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 8.266898e-01 0.083 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 8.266898e-01 0.083 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.266898e-01 0.083 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 8.271241e-01 0.082 0 0
Resolution of D-Loop Structures R-HSA-5693537 8.271241e-01 0.082 0 0
Glutamate and glutamine metabolism R-HSA-8964539 8.271241e-01 0.082 0 0
Miscellaneous transport and binding events R-HSA-5223345 8.271241e-01 0.082 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 8.301008e-01 0.081 0 0
Degradation of CDH1 R-HSA-9766229 8.311368e-01 0.080 0 0
DNA Damage Bypass R-HSA-73893 8.311368e-01 0.080 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 8.318118e-01 0.080 0 0
Collagen formation R-HSA-1474290 8.339368e-01 0.079 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 8.339368e-01 0.079 0 0
Processing of DNA double-strand break ends R-HSA-5693607 8.354184e-01 0.078 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 8.373393e-01 0.077 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.373393e-01 0.077 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 8.373393e-01 0.077 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.373393e-01 0.077 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.373393e-01 0.077 0 0
PI3K Cascade R-HSA-109704 8.397127e-01 0.076 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 8.399704e-01 0.076 0 0
Presynaptic function of Kainate receptors R-HSA-500657 8.399704e-01 0.076 0 0
Synaptic adhesion-like molecules R-HSA-8849932 8.399704e-01 0.076 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 8.400937e-01 0.076 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 8.400937e-01 0.076 0 0
Kidney development R-HSA-9830369 8.468111e-01 0.072 0 0
PERK regulates gene expression R-HSA-381042 8.470050e-01 0.072 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 8.470050e-01 0.072 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.470050e-01 0.072 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.489400e-01 0.071 0 0
Crosslinking of collagen fibrils R-HSA-2243919 8.522340e-01 0.069 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 8.522340e-01 0.069 0 0
Pyrimidine biosynthesis R-HSA-500753 8.522340e-01 0.069 0 0
The NLRP3 inflammasome R-HSA-844456 8.522340e-01 0.069 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 8.522340e-01 0.069 0 0
Diseases of hemostasis R-HSA-9671793 8.522340e-01 0.069 0 0
Other interleukin signaling R-HSA-449836 8.522340e-01 0.069 0 0
Specification of the neural plate border R-HSA-9834899 8.522340e-01 0.069 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 8.522340e-01 0.069 0 0
Maturation of nucleoprotein R-HSA-9694631 8.522340e-01 0.069 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 8.522340e-01 0.069 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 8.557391e-01 0.068 0 0
Regulation of TP53 Degradation R-HSA-6804757 8.561453e-01 0.067 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 8.561453e-01 0.067 0 0
Calmodulin induced events R-HSA-111933 8.561453e-01 0.067 0 0
CaM pathway R-HSA-111997 8.561453e-01 0.067 0 0
Glycosphingolipid transport R-HSA-9845576 8.561453e-01 0.067 0 0
Telomere Maintenance R-HSA-157579 8.585121e-01 0.066 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.625666e-01 0.064 1 1
KEAP1-NFE2L2 pathway R-HSA-9755511 8.634969e-01 0.064 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 8.635584e-01 0.064 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 8.635584e-01 0.064 0 0
Signaling by NODAL R-HSA-1181150 8.635584e-01 0.064 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 8.635584e-01 0.064 0 0
Signal transduction by L1 R-HSA-445144 8.635584e-01 0.064 0 0
Nephrin family interactions R-HSA-373753 8.635584e-01 0.064 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 8.635584e-01 0.064 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 8.671810e-01 0.062 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.679811e-01 0.061 0 0
Interleukin-1 family signaling R-HSA-446652 8.679811e-01 0.061 1 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.729444e-01 0.059 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 8.729444e-01 0.059 0 0
Hedgehog 'on' state R-HSA-5632684 8.734337e-01 0.059 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 8.740157e-01 0.058 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 8.740157e-01 0.058 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 8.740157e-01 0.058 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 8.740157e-01 0.058 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 8.740157e-01 0.058 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 8.740157e-01 0.058 0 0
Basigin interactions R-HSA-210991 8.740157e-01 0.058 0 0
Early Phase of HIV Life Cycle R-HSA-162594 8.740157e-01 0.058 0 0
G alpha (z) signalling events R-HSA-418597 8.771473e-01 0.057 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 8.800099e-01 0.056 0 0
Stabilization of p53 R-HSA-69541 8.806489e-01 0.055 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 8.836720e-01 0.054 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 8.836720e-01 0.054 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 8.836720e-01 0.054 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 8.836720e-01 0.054 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 8.836720e-01 0.054 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 8.836720e-01 0.054 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 8.836720e-01 0.054 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 8.879194e-01 0.052 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 8.879194e-01 0.052 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 8.896654e-01 0.051 0 0
Hemostasis R-HSA-109582 8.925087e-01 0.049 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 8.925887e-01 0.049 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 8.925887e-01 0.049 0 0
Reproduction R-HSA-1474165 8.937763e-01 0.049 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 8.947772e-01 0.048 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 8.947772e-01 0.048 0 0
Platelet activation, signaling and aggregation R-HSA-76002 8.950411e-01 0.048 0 0
Protein ubiquitination R-HSA-8852135 8.959628e-01 0.048 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.008225e-01 0.045 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.008225e-01 0.045 0 0
Organic anion transport by SLCO transporters R-HSA-879518 9.008225e-01 0.045 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 9.012428e-01 0.045 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.012428e-01 0.045 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.012428e-01 0.045 0 0
Viral Infection Pathways R-HSA-9824446 9.036400e-01 0.044 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.053459e-01 0.043 0 0
Toll-like Receptor Cascades R-HSA-168898 9.062871e-01 0.043 1 0
SARS-CoV-1-host interactions R-HSA-9692914 9.070570e-01 0.042 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.073361e-01 0.042 0 0
Depyrimidination R-HSA-73928 9.073361e-01 0.042 0 0
Ca-dependent events R-HSA-111996 9.073361e-01 0.042 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.084255e-01 0.042 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 9.084255e-01 0.042 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 9.084255e-01 0.042 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 9.084255e-01 0.042 0 0
Chromosome Maintenance R-HSA-73886 9.113220e-01 0.040 0 0
PLC beta mediated events R-HSA-112043 9.116710e-01 0.040 0 0
Nucleotide salvage R-HSA-8956321 9.116710e-01 0.040 0 0
Defective pyroptosis R-HSA-9710421 9.130760e-01 0.039 0 0
Signaling by FGFR4 R-HSA-5654743 9.130760e-01 0.039 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.130760e-01 0.039 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 9.154461e-01 0.038 0 0
Defects in cobalamin (B12) metabolism R-HSA-3296469 9.154461e-01 0.038 0 0
Hyaluronan degradation R-HSA-2160916 9.154461e-01 0.038 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.154461e-01 0.038 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 9.154461e-01 0.038 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.154461e-01 0.038 0 0
Laminin interactions R-HSA-3000157 9.154461e-01 0.038 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.154461e-01 0.038 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.162118e-01 0.038 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.183741e-01 0.037 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.184810e-01 0.037 0 0
Signaling by FGFR2 R-HSA-5654738 9.191106e-01 0.037 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 9.198511e-01 0.036 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.210556e-01 0.036 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.219288e-01 0.035 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 9.219288e-01 0.035 0 0
Signaling by EGFR in Cancer R-HSA-1643713 9.219288e-01 0.035 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 9.219288e-01 0.035 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.219288e-01 0.035 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.235685e-01 0.035 0 0
Somitogenesis R-HSA-9824272 9.235685e-01 0.035 0 0
Fanconi Anemia Pathway R-HSA-6783310 9.235685e-01 0.035 0 0
Signaling by FGFR3 R-HSA-5654741 9.235685e-01 0.035 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.240825e-01 0.034 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 9.279149e-01 0.032 0 0
Cobalamin (Cbl) metabolism R-HSA-9759218 9.279149e-01 0.032 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 9.279149e-01 0.032 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 9.279149e-01 0.032 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 9.279149e-01 0.032 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.279149e-01 0.032 0 0
Insulin processing R-HSA-264876 9.279149e-01 0.032 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 9.283556e-01 0.032 0 0
Co-inhibition by PD-1 R-HSA-389948 9.309835e-01 0.031 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.334318e-01 0.030 0 0
Telomere Extension By Telomerase R-HSA-171319 9.334423e-01 0.030 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 9.334423e-01 0.030 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 9.334423e-01 0.030 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 9.334423e-01 0.030 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 9.334423e-01 0.030 0 0
Pyroptosis R-HSA-5620971 9.334423e-01 0.030 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 9.334423e-01 0.030 0 0
Platelet degranulation R-HSA-114608 9.339154e-01 0.030 0 0
Metal ion SLC transporters R-HSA-425410 9.370923e-01 0.028 0 0
G-protein mediated events R-HSA-112040 9.371425e-01 0.028 0 0
Meiosis R-HSA-1500620 9.375342e-01 0.028 0 0
DNA methylation R-HSA-5334118 9.385462e-01 0.028 0 0
Platelet calcium homeostasis R-HSA-418360 9.385462e-01 0.028 0 0
Termination of translesion DNA synthesis R-HSA-5656169 9.385462e-01 0.028 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 9.385462e-01 0.028 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.385462e-01 0.028 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 9.385462e-01 0.028 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 9.385462e-01 0.028 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.406613e-01 0.027 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.410720e-01 0.026 0 0
Neuronal System R-HSA-112316 9.423955e-01 0.026 0 0
Interferon alpha/beta signaling R-HSA-909733 9.431610e-01 0.025 0 0
DAP12 signaling R-HSA-2424491 9.432590e-01 0.025 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.432590e-01 0.025 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.432590e-01 0.025 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 9.432590e-01 0.025 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.432590e-01 0.025 0 0
XBP1(S) activates chaperone genes R-HSA-381038 9.437696e-01 0.025 0 0
SARS-CoV Infections R-HSA-9679506 9.447233e-01 0.025 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.448116e-01 0.025 0 0
COPII-mediated vesicle transport R-HSA-204005 9.471574e-01 0.024 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.476106e-01 0.023 0 0
Cargo concentration in the ER R-HSA-5694530 9.476106e-01 0.023 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.490832e-01 0.023 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 9.506285e-01 0.022 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 9.516235e-01 0.022 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.516288e-01 0.022 0 0
Extracellular matrix organization R-HSA-1474244 9.529534e-01 0.021 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.529867e-01 0.021 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 9.553389e-01 0.020 0 0
Cardiogenesis R-HSA-9733709 9.553389e-01 0.020 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 9.553389e-01 0.020 0 0
Regulation of necroptotic cell death R-HSA-5675482 9.553389e-01 0.020 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 9.569486e-01 0.019 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 9.576277e-01 0.019 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.576277e-01 0.019 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.587647e-01 0.018 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.587647e-01 0.018 0 0
IRE1alpha activates chaperones R-HSA-381070 9.592156e-01 0.018 0 0
Signaling by Insulin receptor R-HSA-74752 9.613717e-01 0.017 0 0
Stimuli-sensing channels R-HSA-2672351 9.615846e-01 0.017 0 0
eNOS activation R-HSA-203615 9.619279e-01 0.017 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.619279e-01 0.017 0 0
Hyaluronan metabolism R-HSA-2142845 9.619279e-01 0.017 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.619279e-01 0.017 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 9.619279e-01 0.017 0 0
Signal amplification R-HSA-392518 9.619279e-01 0.017 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 9.619279e-01 0.017 0 0
Ion homeostasis R-HSA-5578775 9.629142e-01 0.016 0 0
Signaling by FGFR1 R-HSA-5654736 9.629142e-01 0.016 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 9.642384e-01 0.016 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.648487e-01 0.016 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.648487e-01 0.016 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.648487e-01 0.016 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.648487e-01 0.016 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.648487e-01 0.016 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.648487e-01 0.016 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.648487e-01 0.016 0 0
TCR signaling R-HSA-202403 9.653050e-01 0.015 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.675455e-01 0.014 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.675455e-01 0.014 0 0
GPVI-mediated activation cascade R-HSA-114604 9.675455e-01 0.014 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.675455e-01 0.014 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.675455e-01 0.014 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 9.686908e-01 0.014 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 9.686908e-01 0.014 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.689860e-01 0.014 0 0
Cellular response to chemical stress R-HSA-9711123 9.690519e-01 0.014 0 0
Peroxisomal protein import R-HSA-9033241 9.696729e-01 0.013 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.700356e-01 0.013 0 0
Degradation of DVL R-HSA-4641258 9.700356e-01 0.013 0 0
Degradation of AXIN R-HSA-4641257 9.700356e-01 0.013 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.700356e-01 0.013 0 0
NCAM1 interactions R-HSA-419037 9.700356e-01 0.013 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.700356e-01 0.013 0 0
Purine salvage R-HSA-74217 9.723347e-01 0.012 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 9.723347e-01 0.012 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.732019e-01 0.012 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.735015e-01 0.012 0 0
Signaling by FGFR R-HSA-190236 9.737431e-01 0.012 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.744576e-01 0.011 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.744576e-01 0.011 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.744576e-01 0.011 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.744576e-01 0.011 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.745642e-01 0.011 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 9.764177e-01 0.010 0 0
Diseases of Immune System R-HSA-5260271 9.764177e-01 0.010 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 9.768611e-01 0.010 0 0
Interleukin-1 signaling R-HSA-9020702 9.778131e-01 0.010 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.782275e-01 0.010 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.782275e-01 0.010 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.782275e-01 0.010 0 0
Maturation of spike protein R-HSA-9694548 9.782275e-01 0.010 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 9.782275e-01 0.010 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 9.783824e-01 0.009 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.790747e-01 0.009 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.798985e-01 0.009 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.798985e-01 0.009 0 0
Intra-Golgi traffic R-HSA-6811438 9.798985e-01 0.009 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.798985e-01 0.009 0 0
Translation of Structural Proteins R-HSA-9683701 9.798985e-01 0.009 0 0
Leishmania infection R-HSA-9658195 9.806942e-01 0.008 1 0
Parasitic Infection Pathways R-HSA-9824443 9.806942e-01 0.008 1 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.814413e-01 0.008 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.822545e-01 0.008 1 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.828658e-01 0.008 0 0
Pyrimidine catabolism R-HSA-73621 9.828658e-01 0.008 0 0
Regulated Necrosis R-HSA-5218859 9.835545e-01 0.007 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 9.836302e-01 0.007 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.837275e-01 0.007 0 0
DAP12 interactions R-HSA-2172127 9.841811e-01 0.007 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.841811e-01 0.007 0 0
Proteasome assembly R-HSA-9907900 9.841811e-01 0.007 0 0
Surfactant metabolism R-HSA-5683826 9.841811e-01 0.007 0 0
Unfolded Protein Response (UPR) R-HSA-381119 9.847520e-01 0.007 0 0
Neurotransmitter release cycle R-HSA-112310 9.851289e-01 0.007 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 9.853954e-01 0.006 0 0
Nucleosome assembly R-HSA-774815 9.853954e-01 0.006 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.853954e-01 0.006 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.853954e-01 0.006 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.853954e-01 0.006 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.853954e-01 0.006 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 9.856677e-01 0.006 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.856677e-01 0.006 0 0
SARS-CoV-1 Infection R-HSA-9678108 9.865130e-01 0.006 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.865166e-01 0.006 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.865166e-01 0.006 0 0
Immune System R-HSA-168256 9.873114e-01 0.006 1 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.875518e-01 0.005 0 0
Synthesis of PC R-HSA-1483191 9.875518e-01 0.005 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.876720e-01 0.005 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.883505e-01 0.005 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.884226e-01 0.005 0 0
GPER1 signaling R-HSA-9634597 9.885076e-01 0.005 0 0
Gluconeogenesis R-HSA-70263 9.885076e-01 0.005 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.891307e-01 0.005 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.893730e-01 0.005 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 9.901001e-01 0.004 0 0
Regulation of RAS by GAPs R-HSA-5658442 9.902048e-01 0.004 0 0
Complex IV assembly R-HSA-9864848 9.909570e-01 0.004 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.909570e-01 0.004 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.909570e-01 0.004 0 0
Translation of Structural Proteins R-HSA-9694635 9.911778e-01 0.004 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.916515e-01 0.004 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 9.916515e-01 0.004 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.917724e-01 0.004 0 0
Integrin cell surface interactions R-HSA-216083 9.917724e-01 0.004 0 0
Interleukin-10 signaling R-HSA-6783783 9.917724e-01 0.004 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.919370e-01 0.004 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.920826e-01 0.003 0 0
Regulation of insulin secretion R-HSA-422356 9.920826e-01 0.003 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.922927e-01 0.003 0 0
Nucleotide biosynthesis R-HSA-8956320 9.922927e-01 0.003 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.922927e-01 0.003 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.923277e-01 0.003 0 0
Post-translational protein modification R-HSA-597592 9.930835e-01 0.003 0 0
Amyloid fiber formation R-HSA-977225 9.933306e-01 0.003 0 0
Integration of energy metabolism R-HSA-163685 9.934849e-01 0.003 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.939358e-01 0.003 0 0
Phospholipid metabolism R-HSA-1483257 9.941593e-01 0.003 0 0
Dectin-2 family R-HSA-5621480 9.944017e-01 0.002 0 0
Synthesis of PA R-HSA-1483166 9.944017e-01 0.002 0 0
Response of endothelial cells to shear stress R-HSA-9860931 9.946120e-01 0.002 0 0
Opioid Signalling R-HSA-111885 9.946120e-01 0.002 0 0
Cellular response to starvation R-HSA-9711097 9.946924e-01 0.002 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.948318e-01 0.002 0 0
Formation of the cornified envelope R-HSA-6809371 9.951612e-01 0.002 0 0
RAB geranylgeranylation R-HSA-8873719 9.955954e-01 0.002 0 0
Metabolism of polyamines R-HSA-351202 9.955954e-01 0.002 0 0
Adaptive Immune System R-HSA-1280218 9.956025e-01 0.002 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.956295e-01 0.002 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.961039e-01 0.002 0 0
ER-Phagosome pathway R-HSA-1236974 9.964665e-01 0.002 0 0
Neddylation R-HSA-8951664 9.967188e-01 0.001 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.971454e-01 0.001 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.973418e-01 0.001 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.973418e-01 0.001 0 0
FCGR activation R-HSA-2029481 9.975249e-01 0.001 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.975372e-01 0.001 0 0
O-linked glycosylation of mucins R-HSA-913709 9.976769e-01 0.001 0 0
Formation of a pool of free 40S subunits R-HSA-72689 9.980029e-01 0.001 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.980029e-01 0.001 0 0
rRNA processing R-HSA-72312 9.981097e-01 0.001 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.981411e-01 0.001 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.981411e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.981726e-01 0.001 0 0
ECM proteoglycans R-HSA-3000178 9.981726e-01 0.001 0 0
Metabolism of cofactors R-HSA-8978934 9.981726e-01 0.001 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.982817e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.985014e-01 0.001 0 0
ABC-family proteins mediated transport R-HSA-382556 9.986055e-01 0.001 0 0
Iron uptake and transport R-HSA-917937 9.986731e-01 0.001 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.987653e-01 0.001 0 0
ABC transporter disorders R-HSA-5619084 9.989563e-01 0.000 0 0
Cholesterol biosynthesis R-HSA-191273 9.989563e-01 0.000 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 9.991107e-01 0.000 0 0
Neutrophil degranulation R-HSA-6798695 9.991336e-01 0.000 0 0
Platelet homeostasis R-HSA-418346 9.991590e-01 0.000 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.992179e-01 0.000 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.993006e-01 0.000 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.993419e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.993710e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.994403e-01 0.000 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.994500e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.994702e-01 0.000 0 0
Peptide chain elongation R-HSA-156902 9.995674e-01 0.000 0 0
Downstream TCR signaling R-HSA-202424 9.996315e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.996315e-01 0.000 0 0
G alpha (q) signalling events R-HSA-416476 9.996470e-01 0.000 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.996598e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.996739e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.997416e-01 0.000 1 0
Mitochondrial protein degradation R-HSA-9837999 9.997531e-01 0.000 0 0
Ion channel transport R-HSA-983712 9.997558e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.997568e-01 0.000 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.997721e-01 0.000 0 0
Eukaryotic Translation Termination R-HSA-72764 9.997897e-01 0.000 0 0
Potassium Channels R-HSA-1296071 9.998059e-01 0.000 0 0
G alpha (s) signalling events R-HSA-418555 9.998202e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.998436e-01 0.000 0 0
Selenocysteine synthesis R-HSA-2408557 9.998700e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.998747e-01 0.000 0 0
Protein localization R-HSA-9609507 9.998756e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.998853e-01 0.000 0 0
Viral mRNA Translation R-HSA-192823 9.998892e-01 0.000 0 0
Cardiac conduction R-HSA-5576891 9.998996e-01 0.000 0 0
Disease R-HSA-1643685 9.999338e-01 0.000 1 0
Ribosome-associated quality control R-HSA-9948299 9.999445e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999462e-01 0.000 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.999667e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.999667e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.999671e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999790e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999838e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.999909e-01 0.000 1 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.999938e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999955e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.999965e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.999965e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999987e-01 0.000 0 0
Translation R-HSA-72766 9.999990e-01 0.000 0 0
Selenoamino acid metabolism R-HSA-2408522 9.999995e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999998e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999999e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.999999e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999999e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
G alpha (i) signalling events R-HSA-418594 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 -0.000 0 0
Activation of BMF and translocation to mitochondria R-HSA-139910 1.000000e+00 0.000 1 1
Interleukin-38 signaling R-HSA-9007892 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways