ITK

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included
Y Sites Probabilities

Log-Odds: Y Sites / Y Background

Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown

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substrate_uniprot site source substrate_genes site_seq
A0MZ66 Y24 Sugiyama SHTN1 KIAA1598 sDEEKQLQLITsLKEQAIGEyEDLRAENQKTKEKCDKIRQE
A5A3E0 Y1062 Sugiyama POTEF A26C1B GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A5YKK6 Y1572 Sugiyama CNOT1 CDC39 KIAA1007 NOT1 AD-005 RMPEQIRLKVGGVDPKQLAVyEEFARNVPGFLPTNDLSQPT
O00116 Y645 Sugiyama AGPS AAG5 QWLKESIsDVGFGMLKSVKEyVDPNNIFGNRNLL_______
O00233 Y70 Sugiyama PSMD9 IGMNEPLVDCEGyPRSDVDLyQVRTARHNIICLQNDHKAVM
O00299 Y233 Sugiyama CLIC1 G6 NCC27 AyAREEFAstCPDDEEIELAyEQVAKALK____________
O00429 Y101 Sugiyama DNM1L DLP1 DRP1 EENGVEAEEWGKFLHTKNKLyTDFDEIRQEIENETERISGN
O14818 Y145 Sugiyama PSMA7 HSPC RPFGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGA
O14818 Y153 Sugiyama PSMA7 HSPC IVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFLE
O14910 Y133 Sugiyama LIN7A MALS1 VELI1 KTDEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLKRGD
O14950 Y143 Sugiyama MYL12B MRLC2 MYLC2B LRELLttMGDRFtDEEVDELyREAPIDKKGNFNyIEFtRIL
O14950 Y156 Sugiyama MYL12B MRLC2 MYLC2B DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
O14979 Y167 Sugiyama HNRNPDL HNRPDL JKTBP DGKMFIGGLSWDTsKKDLtEyLSRFGEVVDCtIKTDPVTGR
O15067 Y538 Sugiyama PFAS KIAA0361 GAGGNGNVLKELsDPAGAIIytsRFQLGDPTLNALEIWGAE
O15234 Y240 Sugiyama CASC3 MLN51 HDKFREDEQAPKSRQELIALyGyDIRSAHNPDDIKPRRIRK
O15234 Y242 Sugiyama CASC3 MLN51 KFREDEQAPKSRQELIALyGyDIRSAHNPDDIKPRRIRKPR
O15357 Y190 Sugiyama INPPL1 SHIP2 AAESAPNGLSTVSHDYLKGsyGLDLEAVRGGASHLPHLTRT
O15371 Y30 Sugiyama EIF3D EIF3S7 QDNPSGWGPCAVPEQFRDMPyQPFsKGDRLGKVADWtGAty
O15371 Y50 Sugiyama EIF3D EIF3S7 yQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQYA
O43143 Y128 Sugiyama DHX15 DBP1 DDX15 HTSLPQCINPFTNLPHTPRyyDILKKRLQLPVWEYKDRFTD
O43252 Y238 Sugiyama PAPSS1 ATPSK1 PAPSS ELLQERDIVPVDAsYEVKELyVPENKLHLAKTDAETLPALK
O43390 Y136 Sugiyama HNRNPR HNRPR QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O43390 Y296 Sugiyama HNRNPR HNRPR VILYHQPDDKKKNRGFCFLEyEDHKSAAQARRRLMSGKVKV
O43390 Y376 Sugiyama HNRNPR HNRPR ILEKSFSEFGKLERVKKLKDyAFVHFEDRGAAVKAMDEMNG
O43390 Y435 Sugiyama HNRNPR HNRPR KRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGGR
O43390 Y436 Sugiyama HNRNPR HNRPR RKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGGRG
O43707 Y212 Sugiyama ACTN4 WKDGLAFNALIHRHRPELIEyDKLRKDDPVTNLNNAFEVAE
O43707 Y878 Sugiyama ACTN4 DKNFITAEELRRELPPDQAEyCIARMAPyQGPDAVPGALDy
O43765 Y195 Sugiyama SGTA SGT SGT1 HVEAVAYYKKALELDPDNEtyKsNLKIAELKLREAPSPTGG
O43823 Y311 Sugiyama AKAP8 AKAP95 RGFDRFGPDGTGRKRKQFQLyEEPDtKLARVDsEGDFsEND
O43852 Y106 Sugiyama CALU GFVtVDELKDWIKFAQKRWIyEDVERQWKGHDLNEDGLVsW
O43852 Y263 Sugiyama CALU KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
O43852 Y47 Sugiyama CALU RVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQLtPE
O43865 Y291 Sugiyama AHCYL1 DCAL IRBIT XPVKONA LCVPAMNVNDSVTKQKFDNLyCCRESILDGLKRTTDVMFGG
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60506 Y133 Sugiyama SYNCRIP HNRPQ NSAP1 ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O60506 Y293 Sugiyama SYNCRIP HNRPQ NSAP1 VILyHQPDDKKKNRGFCFLEyEDHKTAAQARRRLMSGKVKV
O60664 Y95 Sugiyama PLIN3 M6PRBP1 TIP47 VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE
O60716 Y228 Sugiyama CTNND1 KIAA0384 yPPDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGy
O60814 Y38 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
O60814 Y41 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
O60814 Y43 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
O60841 S186 Sugiyama EIF5B IF2 KIAA0741 EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN
O60841 Y134 Sugiyama EIF5B IF2 KIAA0741 EELEDKDsKSKKTAKPKVEMysGsDDDDDFNKLPKKAKGKA
O75223 Y156 Sugiyama GGCT C7orf24 CRF21 sPQYKKIICMGAKENGLPLEyQEKLKAIEPNDytGKVsEEI
O75347 Y75 Sugiyama TBCA EILQEsRMMIPDCQRRLEAAyLDLQRILENEKDLEEAEEyK
O75348 Y47 Sugiyama ATP6V1G1 ATP6G ATP6G1 ATP6J KRKNRRLKQAKEEAQAEIEQyRLQREKEFKAKEAAALGsRG
O75534 S598 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR KVNKtHsVNGItEEADPTIysGKVIRPLRSVDPTQTEYQGM
O75534 Y597 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR EKVNKtHsVNGItEEADPTIysGKVIRPLRSVDPTQTEYQG
O75718 Y372 Sugiyama CRTAP CASP FQPRPEAVQFFNVTTLQKELyDFAKENIMDDDEGEVVEyVD
O75791 Y45 PSP GRAP2 GADS GRB2L GRID LKILSNQEEWFKAELGsQEGyVPKNFIDIQFPKWFHEGLSR
O94906 Y105 Sugiyama PRPF6 C20orf14 AGSLFSSGPYEKDDEEADAIyAALDKRMDERRKERREQREK
O95218 S120 Sugiyama ZRANB2 ZIS ZNF265 tGYGGGFNERENVEyIEREEsDGEyDEFGRKKKKYRGKAVG
O95218 Y114 Sugiyama ZRANB2 ZIS ZNF265 AKLEERtGYGGGFNERENVEyIEREEsDGEyDEFGRKKKKY
O95218 Y124 Sugiyama ZRANB2 ZIS ZNF265 GGFNERENVEyIEREEsDGEyDEFGRKKKKYRGKAVGPAsI
O95347 Y938 Sugiyama SMC2 CAPE SMC2L1 PRO0324 SKHKREAEDGAAKVSKMLKDyDWINAERHLFGQPNSAYDFK
O95757 Y629 Sugiyama HSPA4L APG1 HSPH3 OSP94 MQDKLEKERNDAKNAVEEyVyDFRDRLGtVYEKFITPEDLS
O96019 Y69 Sugiyama ACTL6A BAF53 BAF53A INO80K DGsTLMEIDGDKGKQGGPtyyIDtNALRVPRENMEAIsPLK
P00338 Y239 Sugiyama LDHA PIG19 GtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVADL
P00491 Y166 Sugiyama PNP NP PLRGPNDERFGDRFPAMsDAyDRtMRQRALstWKQMGEQRE
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P00558 Y196 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MVGVNLPQKAGGFLMKKELNyFAKALEsPERPFLAILGGAK
P00966 Y163 Sugiyama ASS1 ASS APWRMPEFYNRFKGRNDLMEyAKQHGIPIPVtPKNPWSMDE
P02786 Y152 Sugiyama TFRC sEKLDstDFTGtIKLLNENsyVPREAGsQKDENLALyVENQ
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406 Y314 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK
P04406 Y320 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____
P04632 Y87 Sugiyama CAPNS1 CAPN4 CAPNS sAISEAAAQYNPEPPPPRtHysNIEANEsEEVRQFRRLFAQ
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05362 Y455 Sugiyama ICAM1 GtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTRKVTVNVL
P05455 Y104 Sugiyama SSB EDKTKIRRsPsKPLPEVTDEyKNDVKNRsVYIKGFPtDAtL
P05787 Y204 Sugiyama KRT8 CYK8 NKRTEMENEFVLIKKDVDEAyMNKVELESRLEGLTDEINFL
P06493 Y15 Sugiyama CDK1 CDC2 CDC28A CDKN1 P34CDC2 ______MEDyTKIEKIGEGtyGVVyKGRHKTTGQVVAMKKI
P06730 Y197 Sugiyama EIF4E EIF4EL1 EIF4F THIGRVYKERLGLPPKIVIGyQsHADTAtKsGsttKNRFVV
P06733 S268 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 ASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyP
P06733 Y189 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 MILPVGAANFREAMRIGAEVyHNLKNVIKEKyGKDAtNVGD
P06733 Y257 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 TDKVVIGMDVAASEFFRsGKyDLDFKsPDDPsRyIsPDQLA
P06733 Y270 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV
P06733 Y280 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06899 Y38 Sugiyama H2BC11 H2BFR HIST1H2BJ AVTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSK
P06899 Y41 Sugiyama H2BC11 H2BFR HIST1H2BJ KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMG
P07195 Y240 Sugiyama LDHB GTDNDSENWKEVHKMVVEsAyEVIKLKGYTNWAIGLSVADL
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 T101 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB KVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPKEytAGRE
P07237 Y94 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK
P07237 Y99 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB LAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPKEytAG
P07355 Y188 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT
P07355 Y199 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RAEDGsVIDyELIDQDARDLyDAGVKRKGTDVPKWIsIMTE
P07437 Y50 Sugiyama TUBB TUBB5 OK/SW-cl.56 IDPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEP
P07437 Y51 Sugiyama TUBB TUBB5 OK/SW-cl.56 DPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPG
P07686 Y547 Sugiyama HEXB HCC7 DRLTRHRCRMVERGIAAQPLyAGyCNHENM___________
P07711 Y112 Sugiyama CTSL CTSL1 MNGFQNRKPRKGKVFQEPLFyEAPRSVDWREKGyVTPVKNQ
P07737 Y129 Sugiyama PFN1 tLVLLMGKEGVHGGLINKKCyEMAsHLRRsQY_________
P07814 Y1504 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KPLCELQPGAKCVCGKNPAKyytLFGRsy____________
P07814 Y1505 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PLCELQPGAKCVCGKNPAKyytLFGRsy_____________
P07814 Y827 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK
P07858 Y244 Sugiyama CTSB CPSB HYGYNSYSVSNSEKDIMAEIyKNGPVEGAFSVYSDFLLYKS
P07900 Y197 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA GEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIGyP
P07900 Y284 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI
P07900 Y309 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF
P07900 Y313 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG
P07900 Y438 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KKCLELFtELAEDKENyKKFyEQFSKNIKLGIHEDsQNRKK
P07900 Y492 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLR
P07900 Y493 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLRK
P07900 Y61 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KEIFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLI
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 Y192 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIGyP
P08238 Y276 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI
P08238 Y301 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF
P08238 Y305 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG
P08238 Y430 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KKCLELFsELAEDKENyKKFyEAFSKNLKLGIHEDstNRRR
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08238 Y472 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKE
P08238 Y484 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR
P08238 Y485 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVRK
P08238 Y56 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEIFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDII
P08238 Y619 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR
P08708 S89 Sugiyama RPS17 RPS17L ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09211 Y50 Sugiyama GSTP1 FAEES3 GST3 KEEVVTVETWQEGsLKASCLyGQLPKFQDGDLtLyQsNtIL
P09234 T11 Sugiyama SNRPC __________MPKFyCDyCDtyLtHDsPsVRKTHCSGRKHK
P09234 Y12 Sugiyama SNRPC _________MPKFyCDyCDtyLtHDsPsVRKTHCSGRKHKE
P09496 Y147 Sugiyama CLTA NSRKQEAEWKEKAIKELEEWyARQDEQLQKTKANNRVADEA
P09651 Y341 Sugiyama HNRNPA1 HNRPA1 QSSNFGPMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGss
P09651 Y347 Sugiyama HNRNPA1 HNRPA1 PMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGssssssyG
P09972 Y358 Sugiyama ALDOC ALDC AAQGKYEGSGEDGGAAAQsLyIANHAY______________
P0CG38 Y1062 Sugiyama POTEI GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG39 Y1025 Sugiyama POTEJ GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0DPH7 Y224 Sugiyama TUBA3C TUBA2 VDNEAIYDICRRNLDIERPtytNLNRLIGQIVSSITASLRF
P10398 Y155 Sugiyama ARAF ARAF1 PKS PKS2 HCSSKVPTVCVDMSTNRQQFyHsVQDLsGGsRQHEAPsNRP
P10412 Y71 Sugiyama H1-4 H1F4 HIST1H1E SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P10747 Y191 GPS6|SIGNOR|ELM|iPTMNet|EPSD CD28 TVAFIIFWVRSKRSRLLHsDyMNMtPRRPGPTRKHyQPyAP
P10747 Y206 SIGNOR|iPTMNet|EPSD CD28 LLHsDyMNMtPRRPGPTRKHyQPyAPPRDFAAyRS______
P10747 Y209 GPS6|SIGNOR|ELM|iPTMNet|EPSD CD28 sDyMNMtPRRPGPTRKHyQPyAPPRDFAAyRS_________
P10747 Y218 GPS6|SIGNOR|ELM|iPTMNet|EPSD CD28 RPGPTRKHyQPyAPPRDFAAyRS__________________
P10809 Y243 Sugiyama HSPD1 HSP60 yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 T37 Sugiyama HSPA8 HSC70 HSP73 HSPA10 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P11142 Y134 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FYPEEVSSMVLTKMKEIAEAyLGKtVTNAVVtVPAyFNDsQ
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11142 Y545 Sugiyama HSPA8 HSC70 HSP73 HSPA10 YKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKINDE
P11940 Y194 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF
P11940 Y291 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 ERQTELKRKFEQMKQDRITRyQGVNLyVKNLDDGIDDERLR
P11940 Y297 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KRKFEQMKQDRITRyQGVNLyVKNLDDGIDDERLRKEFsPF
P12268 Y509 Sugiyama IMPDH2 IMPD2 KFEKRtssAQVEGGVHsLHsyEKRLF_______________
P12277 Y125 Sugiyama CKB CKBB EHKTDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPH
P12277 Y39 Sugiyama CKB CKBB EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT
P12814 Y842 Sugiyama ACTN1 DTDTADQVMASFKILAGDKNyITMDELRRELPPDQAEyCIA
P12814 Y859 Sugiyama ACTN1 DKNyITMDELRRELPPDQAEyCIARMAPYTGPDSVPGALDY
P13639 Y373 Sugiyama EEF2 EF2 MITIHLPSPVTAQKyRCELLyEGPPDDEAAMGIKsCDPKGP
P13639 Y443 Sugiyama EEF2 EF2 TGLKVRIMGPNytPGKKEDLyLKPIQRTILMMGRYVEPIED
P13639 Y634 Sugiyama EEF2 EF2 AEDIDKGEVsARQELKQRARyLAEKyEWDVAEARKIWCFGP
P13639 Y639 Sugiyama EEF2 EF2 KGEVsARQELKQRARyLAEKyEWDVAEARKIWCFGPDGTGP
P13639 Y671 Sugiyama EEF2 EF2 CFGPDGTGPNILTDITKGVQyLNEIKDSVVAGFQWATKEGA
P13639 Y730 Sugiyama EEF2 EF2 HADAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQ
P13667 Y448 Sugiyama PDIA4 ERP70 ERP72 RAATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLs
P13667 Y458 Sugiyama PDIA4 ERP70 ERP72 VLEVAKDFPEytFAIADEEDyAGEVKDLGLsEsGEDVNAAI
P13667 Y565 Sugiyama PDIA4 ERP70 ERP72 DVLIEFYAPWCGHCKQLEPVyNsLAKKYKGQKGLVIAKMDA
P13674 Y141 Sugiyama P4HA1 P4HA FPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSF
P13674 Y282 Sugiyama P4HA1 P4HA ASDDQSDQKTTPKKKGVAVDyLPERQKyEMLCRGEGIKMTP
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P13987 Y87 Sugiyama CD59 MIC11 MIN1 MIN2 MIN3 MSK21 FEHCNFNDVtTRLRENELtyyCCKKDLCNFNEQLENGGTSL
P14314 Y106 Sugiyama PRKCSH G19P1 yIPSNRVNDGVCDCCDGtDEyNsGVICENtCKEKGRKEREs
P14314 Y465 Sugiyama PRKCSH G19P1 sLGtWGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLC
P14625 Y527 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 AKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAGsSRK
P14625 Y539 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDItsLDQyVERMKEKQDKIyFMAGsSRKEAEssPFVERLL
P14649 Y86 Sugiyama MYL6B MLC1SA LEEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVL
P15259 Y92 Sugiyama PGAM2 PGAMM DGTDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQV
P15311 Y424 Sugiyama EZR VIL2 ERQAVDQIKsQEQLAAELAEytAKIALLEEARRRKEDEVEE
P15880 S264 Sugiyama RPS2 RPS4 ISKTysyLtPDLWKEtVFtKsPyQEFtDHLVKtHtRVsVQR
P15880 Y248 Sugiyama RPS2 RPS4 GCtAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQE
P15880 Y250 Sugiyama RPS2 RPS4 tAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQEFt
P15880 Y266 Sugiyama RPS2 RPS4 KTysyLtPDLWKEtVFtKsPyQEFtDHLVKtHtRVsVQRtQ
P16402 Y72 Sugiyama H1-3 H1F3 HIST1H1D SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P16403 Y71 Sugiyama H1-2 H1F2 HIST1H1C SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17066 Y43 Sugiyama HSPA6 HSP70B' FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P17844 Y59 Sugiyama DDX5 G17P1 HELR HLR1 EKLVKKKWNLDELPKFEKNFyQEHPDLARRtAQEVETYRRS
P17931 Y221 Sugiyama LGALS3 MAC2 QVLVEPDHFKVAVNDAHLLQyNHRVKKLNEISKLGISGDID
P17987 Y545 Sugiyama TCP1 CCT1 CCTA LRIDDLIKLHPESKDDKHGsyEDAVHsGALND_________
P18124 Y155 Sugiyama RPL7 IVEPYIAWGYPNLKsVNELIyKRGYGKINKKRIALtDNALI
P18124 Y82 Sugiyama RPL7 RQMYRTEIRMARMARKAGNFyVPAEPKLAFVIRIRGINGVS
P18615 Y133 Sugiyama NELFE RD RDBP sIsADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEA
P18615 Y170 Sugiyama NELFE RD RDBP GEEAEGPGAGDGPPRsFDWGyEERSGAHSsAsPPRsRSRDR
P18615 Y367 Sugiyama NELFE RD RDBP SLAVQNsPKGCHRDKRTQIVysDDVyKENLVDGF_______
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18669 S137 Sugiyama PGAM1 PGAMA CDABP0006 RsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLK
P18669 Y133 Sugiyama PGAM1 PGAMA CDABP0006 KIWRRsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsC
P18669 Y142 Sugiyama PGAM1 PGAMA CDABP0006 PPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIAR
P18669 Y26 Sugiyama PGAM1 PGAMA CDABP0006 LVLIRHGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALR
P18669 Y92 Sugiyama PGAM1 PGAMA CDABP0006 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
P19105 Y142 Sugiyama MYL12A MLCB MRLC3 RLC LRELLttMGDRFtDEEVDELyREAPIDKKGNFNyIEFtRIL
P19105 Y155 Sugiyama MYL12A MLCB MRLC3 RLC DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
P19174 Y783 GPS6|EPSD|PSP PLCG1 PLC1 KIGTAEPDyGALyEGRNPGFyVEANPMPTFKCAVKALFDYK
P19338 Y462 Sugiyama NCL AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs
P20042 Y176 Sugiyama EIF2S2 EIF2B GIsFsNQtGPAWAGSERDytyEELLNRVFNIMREKNPDMVA
P20618 Y150 Sugiyama PSMB1 PSC5 FPYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSAS
P21127 Y449 Sugiyama CDK11B CDC2L1 CDK11 PITSLREA PK58 LQGCRsVEEFQCLNRIEEGtyGVVYRAKDKKTDEIVALKRL
P21980 T368 Sugiyama TGM2 QPGYEGWQALDPTPQEKsEGtyCCGPVPVRAIKEGDLstKy
P22087 Y118 Sugiyama FBL FIB1 FLRN ICRGKEDALVTKNLVPGEsVyGEKRVsIsEGDDKIEyRAWN
P22234 Y22 Sugiyama PAICS ADE2 AIRC PAIS AtAEVLNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAG
P22314 Y451 Sugiyama UBA1 A1S9T UBE1 CLPEDKEVLTEDKCLQRQNRyDGQVAVFGsDLQEKLGKQKY
P22314 Y55 Sugiyama UBA1 A1S9T UBE1 SVPTNGMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSV
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P22492 Y75 Sugiyama H1-6 H1FT H1T HIST1H1T SQERVGMSLVALKKALAAAGyDVEKNNSRIKLSLKSLVNKG
P22626 S341 Sugiyama HNRNPA2B1 HNRPA2B1 FGGsRNMGGPyGGGNyGPGGsGGsGGyGGRsRy________
P22626 S344 Sugiyama HNRNPA2B1 HNRPA2B1 sRNMGGPyGGGNyGPGGsGGsGGyGGRsRy___________
P22626 Y347 Sugiyama HNRNPA2B1 HNRPA2B1 MGGPyGGGNyGPGGsGGsGGyGGRsRy______________
P23193 Y126 Sugiyama TCEA1 GTF2S TFIIS EsTSsGNVsNRKDETNARDTyVsSFPRAPstsDsVRLKCRE
P23246 S491 Sugiyama SFPQ PSF QKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQVEKN
P23246 Y488 Sugiyama SFPQ PSF PMYQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQV
P23246 Y490 Sugiyama SFPQ PSF YQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQVEK
P23284 Y119 Sugiyama PPIB CYPB DFMIQGGDFtRGDGtGGKsIyGERFPDENFKLKHyGPGWVs
P23396 S35 Sugiyama RPS3 OK/SW-cl.26 GIFKAELNEFLtRELAEDGysGVEVRVtPTRTEIIILATRT
P23396 Y34 Sugiyama RPS3 OK/SW-cl.26 DGIFKAELNEFLtRELAEDGysGVEVRVtPTRTEIIILATR
P23434 Y139 Sugiyama GCSH EVTEINEALAENPGLVNKSCyEDGWLIKMtLsNPsELDELM
P23526 Y165 Sugiyama AHCY SAHH QLLPGIRGIsEEtTTGVHNLyKMMANGILKVPAINVNDsVt
P23526 Y193 Sugiyama AHCY SAHH LKVPAINVNDsVtKsKFDNLyGCRESLIDGIKRATDVMIAG
P23527 Y38 Sugiyama H2BC17 H2BFH H2BFN HIST1H2BO AVTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSK
P23527 Y41 Sugiyama H2BC17 H2BFH H2BFN HIST1H2BO KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMG
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23528 T88 Sugiyama CFL1 CFL yAtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPES
P23528 Y140 Sugiyama CFL1 CFL SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs
P23528 Y85 Sugiyama CFL1 CFL DDPyAtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWA
P23528 Y89 Sugiyama CFL1 CFL AtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPESA
P24752 Y214 Sugiyama ACAT1 ACAT MAT GsCAENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNE
P24752 Y90 Sugiyama ACAT1 ACAT MAT IAIQGAIEKAGIPKEEVKEAyMGNVLQGGEGQAPTRQAVLG
P24941 Y15 Sugiyama CDK2 CDKN2 ______MENFQKVEKIGEGtyGVVyKARNKLTGEVVALKKI
P25205 Y32 Sugiyama MCM3 LREAQRDyLDFLDDEEDQGIyQsKVRELIsDNQyRLIVNVN
P25205 Y45 Sugiyama MCM3 DEEDQGIyQsKVRELIsDNQyRLIVNVNDLRRKNEKRANRL
P25398 Y127 Sugiyama RPS12 sCVVVKDYGKESQAKDVIEEyFKCKK_______________
P25685 Y52 Sugiyama DNAJB1 DNAJ1 HDJ1 HSPF1 HPDKNKEPGAEEKFKEIAEAyDVLSDPRKREIFDRYGEEGL
P25786 Y6 Sugiyama PSMA1 HC2 NU PROS30 PSC2 _______________MFRNQyDNDVtVWsPQGRIHQIEYAM
P25787 Y57 Sugiyama PSMA2 HC3 PSC3 GIKAANGVVLATEKKQKSILyDERSVHKVEPITKHIGLVys
P26196 Y469 Sugiyama DDX6 HLR2 RCK IEEQLGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP______
P26196 Y473 Sugiyama DDX6 HLR2 RCK LGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP__________
P26640 Y601 Sugiyama VARS1 G7A VARS VARS2 VDMDFGTGAVKITPAHDQNDyEVGQRHGLEAIsIMDsRGAL
P26885 Y112 Sugiyama FKBP2 FKBP13 GLLGMCEGEKRKLVIPsELGyGERGAPPKIPGGATLVFEVE
P27348 Y149 Sugiyama YWHAQ LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG
P27695 S129 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 QELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDE
P27695 Y128 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 LQELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGD
P27695 Y144 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 DKEGysGVGLLsRQCPLKVsyGIGDEEHDQEGRVIVAEFDS
P27695 Y45 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 KSKTAAKKNDKEAAGEGPALyEDPPDQKtsPsGKPAtLKIC
P27797 Y109 Sugiyama CALR CRTC QTLVVQFTVKHEQNIDCGGGyVKLFPNSLDQTDMHGDSEYN
P28074 Y236 Sugiyama PSMB5 LMPX MB1 X RRAIyQATYRDAysGGAVNLyHVREDGWIRVSsDNVADLHE
P29353 Y427 Sugiyama SHC1 SHC SHCA RKQMPPPPPCPGRELFDDPsyVNVQNLDKARQAVGGAGPPN
P29401 S308 Sugiyama TKT PPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQALAKL
P29401 Y202 Sugiyama TKT LDINRLGQsDPAPLQHQMDIyQKRCEAFGWHAIIVDGHSVE
P29401 Y481 Sugiyama TKT AANTKGICFIRTsRPENAIIyNNNEDFQVGQAKVVLKSKDD
P29692 Y26 Sugiyama EEF1D EF1D LAHEKIWFDKFKYDDAERRFyEQMNGPVAGAsRQENGAsVI
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P30086 Y106 Sugiyama PEBP1 PBP PEBP HFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLHRyVWLVyE
P30086 Y176 Sugiyama PEBP1 PBP PEBP KKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK_________
P30086 Y181 Sugiyama PEBP1 PBP PEBP RAPVAGtCyQAEWDDyVPKLyEQLsGK______________
P30086 Y64 Sugiyama PEBP1 PBP PEBP tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW
P30101 Y100 Sugiyama PDIA3 ERP57 ERP60 GRP58 LAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRt
P30101 Y115 Sugiyama PDIA3 ERP57 ERP60 GRP58 yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA
P30101 Y445 Sugiyama PDIA3 ERP57 ERP60 GRP58 KDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLNPK
P30101 Y67 Sugiyama PDIA3 ERP57 ERP60 GRP58 LMLVEFFAPWCGHCKRLAPEyEAAAtRLKGIVPLAKVDCTA
P30101 Y95 Sugiyama PDIA3 ERP57 ERP60 GRP58 KGIVPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAy
P31153 Y242 Sugiyama MAT2A AMS2 MATA2 LKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLt
P31327 Y1450 Sugiyama CPS1 GsIDLVINLPNNNTKFVHDNyVIRRTAVDSGIPLLTNFQVT
P31943 Y266 Sugiyama HNRNPH1 HNRPH HNRPH1 yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst
P31946 Y21 Sugiyama YWHAB MTMDKsELVQKAKLAEQAERyDDMAAAMKAVtEQGHELsNE
P31947 Y151 Sugiyama SFN HME1 LAEVATGDDKKRIIDSARsAyQEAMDISKKEMPPTNPIRLG
P31947 Y19 Sugiyama SFN HME1 __MERASLIQKAKLAEQAERyEDMAAFMKGAVEKGEELsCE
P31948 Y354 Sugiyama STIP1 DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG
P32119 Y115 Sugiyama PRDX2 NKEFB TDPX1 GLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFIIDGK
P32969 Y180 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 LIQQATTVKNKDIRKFLDGIyVsEKGtVQQADE________
P33121 Y693 Sugiyama ACSL1 FACL1 FACL2 LACS LACS1 LACS2 TMKAKRPELRNYFRSQIDDLyStIKV_______________
P33316 Y167 Sugiyama DUT PPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDVGAG
P33778 Y38 Sugiyama H2BC3 H2BFF HIST1H2BB AITKAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSK
P33778 Y41 Sugiyama H2BC3 H2BFF HIST1H2BB KAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKAMG
P33993 Y102 Sugiyama MCM7 CDC47 MCM2 QELLPQYKEREVVNKDVLDVyIEHRLMMEQRSRDPGMVRsP
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931 T39 Sugiyama HSPA1L CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P34932 S31 Sugiyama HSPA4 APG2 HSPH2 QSCYVAVARAGGIETIANEysDRCtPACIsFGPKNRSIGAA
P34932 Y30 Sugiyama HSPA4 APG2 HSPH2 FQSCYVAVARAGGIETIANEysDRCtPACIsFGPKNRSIGA
P34932 Y336 Sugiyama HSPA4 APG2 HSPH2 RVEPPLRSVLEQTKLKKEDIyAVEIVGGATRIPAVKEKISK
P34932 Y597 Sugiyama HSPA4 APG2 HSPH2 VDLPIENQLLWQIDREMLNLyIENEGKMIMQDKLEKERNDA
P34932 Y624 Sugiyama HSPA4 APG2 HSPH2 MIMQDKLEKERNDAKNAVEEyVyEMRDKLSGEYEKFVSEDD
P34932 Y626 Sugiyama HSPA4 APG2 HSPH2 MQDKLEKERNDAKNAVEEyVyEMRDKLSGEYEKFVSEDDRN
P35637 Y325 Sugiyama FUS TLS FKQIGIIKTNKKTGQPMINLyTDRETGKLKGEAtVsFDDPP
P35637 Y468 Sugiyama FUS TLS KAPKPDGPGGGPGGsHMGGNyGDDRRGGRGGYDRGGYRGRG
P37802 Y192 Sugiyama TAGLN2 KIAA0120 CDABP0035 NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P38646 Y196 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 EtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNV
P38646 Y652 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 NIRQAAssLQQASLKLFEMAyKKMAsEREGSGsSGTGEQKE
P39019 Y48 Sugiyama RPS19 LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P40261 Y11 Sugiyama NNMT __________MESGFTSKDTyLSHFNPRDYLEKYYKFGSRH
P40429 Y149 Sugiyama RPL13A LKPTRKFAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYR
P40925 Y210 Sugiyama MDH1 MDHA tQYPDVNHAKVKLQGKEVGVyEALKDDsWLKGEFVttVQQR
P40939 Y637 Sugiyama HADHA HADH ELLTQMVSKGFLGRKSGKGFyIyQEGVKRKDLNSDMDSILA
P40939 Y639 Sugiyama HADHA HADH LTQMVSKGFLGRKSGKGFyIyQEGVKRKDLNSDMDSILASL
P41227 Y145 Sugiyama NAA10 ARD1 ARD1A TE2 TLNFQISEVEPKyyADGEDAyAMKRDLtQMADELRRHLELK
P42025 Y33 Sugiyama ACTR1B CTRN2 VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALE
P42025 Y38 Sugiyama ACTR1B CTRN2 SGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALEGDLFI
P42680 Y206 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP TEC PSCTK4 AMyDFQAAEGHDLRLERGQEyLILEKNDVHWWRARDKYGNE
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P43243 Y202 Sugiyama MATR3 KIAA0723 RHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDD
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P43490 Y34 Sugiyama NAMPT PBEF PBEF1 ATDSYKVTHYKQYPPNTSKVysyFECREKKTENSKLRKVKY
P46777 Y207 Sugiyama RPL5 MSTP030 sKEFNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyI
P46777 Y210 Sugiyama RPL5 MSTP030 FNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyIKNs
P46777 Y219 Sugiyama RPL5 MSTP030 IMGQNVADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEM
P46777 Y240 Sugiyama RPL5 MSTP030 KKQFsQyIKNsVtPDMMEEMyKKAHAAIRENPVyEKKPKKE
P46777 Y253 Sugiyama RPL5 MSTP030 PDMMEEMyKKAHAAIRENPVyEKKPKKEVKKKRWNRPKMsL
P46778 T29 Sugiyama RPL21 RGTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQ
P46778 Y156 Sugiyama RPL21 REAHFVRTNGKEPELLEPIPyEFMA________________
P46778 Y30 Sugiyama RPL21 GTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQK
P46940 Y1095 Sugiyama IQGAP1 KIAA0051 VVKEIMDDKSLNIKTDPVDIyKsWVNQMESQTGEASKLPyD
P47224 Y114 Sugiyama RABIF MSS4 RASGRF3 CADCEIGPIGWHCLDDKNSFyVALERVSHE___________
P47756 Y232 Sugiyama CAPZB NIGRLVEDMENKIRstLNEIyFGKTKDIVNGLRSVQTFADK
P47914 Y98 Sugiyama RPL29 PKEVKPKIPKGVSRKLDRLAyIAHPKLGKRARARIAKGLRL
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P48741 Y43 Sugiyama HSPA7 HSP70B FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P49207 Y32 Sugiyama RPL34 sYNtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGR
P49207 Y34 Sugiyama RPL34 NtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGRLR
P49321 Y540 Sugiyama NASP DMLDLAKIIFKRQETKEAQLyAAQAHLKLGEVSVESENYVQ
P49327 Y277 Sugiyama FASN FAS KEQGVtFPsGDIQEQLIRSLyQsAGVAPEsFEyIEAHGtGT
P49327 Y289 Sugiyama FASN FAS QEQLIRSLyQsAGVAPEsFEyIEAHGtGTKVGDPQELNGIt
P49327 Y45 Sugiyama FASN FAS NLIGGVDMVTDDDRRWKAGLyGLPRRsGKLKDLSRFDAsFF
P49419 T67 Sugiyama ALDH7A1 ATQ1 LREENEGVyNGSWGGRGEVIttyCPANNEPIARVRQAsVAD
P50454 Y246 Sugiyama SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 VTRSYTVGVMMMHRTGLyNyyDDEKEKLQIVEMPLAHKLsS
P50990 Y30 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 GFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTTRTAYGPN
P51116 Y614 Sugiyama FXR2 FMR1L2 RGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLERTKPs
P51813 Y216 SIGNOR|iPTMNet|EPSD|PSP BMX NESKKNyGSQPPsSSTSLAQyDSNSKKIyGSQPNFNMQYIP
P51813 Y224 SIGNOR|iPTMNet|EPSD BMX SQPPsSSTSLAQyDSNSKKIyGSQPNFNMQYIPREDFPDWW
P51965 Y77 Sugiyama UBE2E1 UBCH6 ADITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
P52272 Y681 Sugiyama HNRNPM HNRPM NAGR1 PFDFTWKMLKDKFNECGHVLyADIKMENGKSKGCGVVKFEs
P52597 Y266 Sugiyama HNRNPF HNRPF ySGLSDGYGFTTDLFGRDLsyCLsGMyDHRYGDsEFtVQsT
P53396 Y659 Sugiyama ACLY TGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISRTTD
P53621 S730 Sugiyama COPA TGNLEKLRKMMKIAEIRKDMsGHyQNALyLGDVSERVRILK
P53621 Y738 Sugiyama COPA KMMKIAEIRKDMsGHyQNALyLGDVSERVRILKNCGQKsLA
P54105 Y214 Sugiyama CLNS1A CLCI ICLN QsVssQYNMAGVRtEDsIRDyEDGMEVDttPtVAGQFEDAD
P54577 Y388 Sugiyama YARS1 YARS LDIRVGKIITVEKHPDADsLyVEKIDVGEAEPRTVVSGLVQ
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652 T38 Sugiyama HSPA2 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55060 Y369 Sugiyama CSE1L CAS XPO2 VPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAACDL
P55209 Y106 Sugiyama NAP1L1 NRP VKCAQIEAKFyEEVHDLERKyAVLyQPLFDKRFEIINAIYE
P55209 Y110 Sugiyama NAP1L1 NRP QIEAKFyEEVHDLERKyAVLyQPLFDKRFEIINAIYEPTEE
P55209 Y96 Sugiyama NAP1L1 NRP RRVNALKNLQVKCAQIEAKFyEEVHDLERKyAVLyQPLFDK
P55795 Y266 Sugiyama HNRNPH2 FTP3 HNRPH2 YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst
P55884 Y768 Sugiyama EIF3B EIF3S9 ERRRTMMEDFRKYRKMAQELyMEQKNERLELRGGVDTDELD
P57053 Y38 Sugiyama H2BC12L H2BFS H2BS1 AVTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssK
P57053 Y41 Sugiyama H2BC12L H2BFS H2BS1 KAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
P57053 Y43 Sugiyama H2BC12L H2BFS H2BS1 QKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P58876 Y38 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
P58876 Y41 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
P58876 Y43 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 Y209 Sugiyama TPI1 TPI LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG
P60228 Y445 Sugiyama EIF3E EIF3S6 INT6 KLNQNSRSEAPNWAtQDsGFy____________________
P60660 Y29 Sugiyama MYL6 TAEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVL
P60660 Y86 Sugiyama MYL6 DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG
P60660 Y89 Sugiyama MYL6 HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI
P60709 Y198 Sugiyama ACTB LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y362 Sugiyama ACTB GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P60842 Y197 Sugiyama EIF4A1 DDX2A EIF4A KMFVLDEADEMLsRGFKDQIyDIFQKLNsNtQVVLLSATMP
P60842 Y70 Sugiyama EIF4A1 DDX2A EIF4A yGFEKPsAIQQRAILPCIKGyDVIAQAQsGtGKTATFAISI
P60900 Y160 Sugiyama PSMA6 PROS27 LIGIDEEQGPQVYKCDPAGyyCGFKATAAGVKQtEstsFLE
P61081 T176 Sugiyama UBE2M UBC12 NRRLFEQNVQRSMRGGyIGstyFERCLK_____________
P61081 Y172 Sugiyama UBE2M UBC12 VLQNNRRLFEQNVQRSMRGGyIGstyFERCLK_________
P61081 Y177 Sugiyama UBE2M UBC12 RRLFEQNVQRSMRGGyIGstyFERCLK______________
P61163 Y33 Sugiyama ACTR1A CTRN1 VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALE
P61163 Y38 Sugiyama ACTR1A CTRN1 SGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALEGDIFI
P61247 Y256 Sugiyama RPS3A FTE1 MFTL sssGKAtGDEtGAKVERADGyEPPVQEsV____________
P61247 Y31 Sugiyama RPS3A FTE1 MFTL KGGKKGAKKKVVDPFSKKDWyDVKAPAMFNIRNIGKTLVTR
P61313 Y6 Sugiyama RPL15 EC45 TCBAP0781 _______________MGAYKyIQELWRKKQSDVMRFLLRVR
P61313 Y62 Sugiyama RPL15 EC45 TCBAP0781 PTRPDKARRLGYKAKQGyVIyRIRVRRGGRKRPVPKGAtyG
P61353 S39 Sugiyama RPL27 SGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVTAAMGK
P61353 Y38 Sugiyama RPL27 YSGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVTAAMG
P61353 Y85 Sugiyama RPL27 RSKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPA
P61604 Y88 Sugiyama HSPE1 GDKVLLPEyGGtKVVLDDKDyFLFRDGDILGKyVD______
P61978 T70 Sugiyama HNRNPK HNRPK QSKNAGAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsI
P61978 Y323 Sugiyama HNRNPK HNRPK RARNLPLPPPPPPRGGDLMAyDRRGRPGDRYDGMVGFSADE
P61978 Y72 Sugiyama HNRNPK HNRPK KNAGAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISA
P61981 T31 Sugiyama YWHAG ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN
P61981 Y20 Sugiyama YWHAG _MVDREQLVQKARLAEQAERyDDMAAAMKNVtELNEPLsNE
P62081 Y177 Sugiyama RPS7 HLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEFQL___
P62191 Y184 Sugiyama PSMC1 MDDTDPLVTVMKVEKAPQETyADIGGLDNQIQEIKESVELP
P62191 Y439 Sugiyama PSMC1 FKKSKENVLyKKQEGtPEGLyL___________________
P62195 S120 Sugiyama PSMC5 SUG1 DKNIDINDVtPNCRVALRNDsytLHKILPNKVDPLVSLMMV
P62195 Y121 Sugiyama PSMC5 SUG1 KNIDINDVtPNCRVALRNDsytLHKILPNKVDPLVSLMMVE
P62241 S115 Sugiyama RPS8 OK/SW-cl.83 TLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEE
P62241 Y113 Sugiyama RPS8 OK/SW-cl.83 TKTLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEE
P62241 Y117 Sugiyama RPS8 OK/SW-cl.83 VKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEEIL
P62249 Y115 Sugiyama RPS16 YYQKYVDEASKKEIKDILIQyDRtLLVADPRRCESKKFGGP
P62258 Y152 Sugiyama YWHAE LAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLG
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62269 Y95 Sugiyama RPS18 D6S218E RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 Y18 Sugiyama RPS13 ___MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVKEQIy
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62280 Y55 Sugiyama RPS11 RYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILsG
P62312 Y72 Sugiyama LSM6 VNGQLKNKyGDAFIRGNNVLyIstQKRRM____________
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62750 Y117 Sugiyama RPL23A VFIVDVKANKHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAY
P62750 Y144 Sugiyama RPL23A VNtLIRPDGEKKAYVRLAPDyDALDVANKIGII________
P62750 Y74 Sugiyama RPL23A LRRQPKYPRKSAPRRNKLDHyAIIKFPLTTEsAMKKIEDNN
P62753 Y156 Sugiyama RPS6 OK/SW-cl.2 KRASRIRKLFNLsKEDDVRQyVVRKPLNKEGKKPRTKAPKI
P62753 Y28 Sugiyama RPS6 OK/SW-cl.2 PAtGCQKLIEVDDERKLRtFyEKRMAtEVAADALGEEWKGY
P62805 Y52 Sugiyama H4C1 H4/A H4FA HIST1H4A; H4C2 H4/I H4FI HIST1H4B; H4C3 H4/G H4FG HIST1H4C; H4C4 H4/B H4FB HIST1H4D; H4C5 H4/J H4FJ HIST1H4E; H4C6 H4/C H4FC HIST1H4F; H4C8 H4/H H4FH HIST1H4H; H4C9 H4/M H4FM HIST1H4I; H4C11 H4/E H4FE HIST1H4J; H4C12 H4/D H4FD HIST1H4K; H4C13 H4/K H4FK HIST1H4L; H4C14 H4/N H4F2 H4FN HIST2H4 HIST2H4A; H4C15 H4/O H4FO HIST2H4B; H4C16 H4-16 HIST4H4 KPAIRRLARRGGVKRIsGLIyEETRGVLKVFLENVIRDAVt
P62807 Y38 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI AVTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssK
P62807 Y41 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI KAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMG
P62807 Y43 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI QKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P62826 Y146 Sugiyama RAN ARA24 OK/SW-cl.81 IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR
P62826 Y147 Sugiyama RAN ARA24 OK/SW-cl.81 KDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARK
P62847 Y76 Sugiyama RPS24 FVFGFRTHFGGGKttGFGMIyDsLDyAKKNEPKHRLARHGL
P62847 Y81 Sugiyama RPS24 RTHFGGGKttGFGMIyDsLDyAKKNEPKHRLARHGLYEKKK
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62899 Y25 Sugiyama RPL31 KKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRA
P62906 Y11 Sugiyama RPL10A NEDD6 __________MSSKVsRDtLyEAVREVLHGNQRKRRKFLET
P62913 Y170 Sugiyama RPL11 CIGAKHRISKEEAMRWFQQKyDGIILPGK____________
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62979 Y148 Sugiyama RPS27A UBA80 UBCEP1 AGVFMAsHFDRHyCGKCCLtyCFNKPEDK____________
P63104 Y149 Sugiyama YWHAZ LAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLG
P63220 T52 Sugiyama RPS21 IQMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRL
P63220 Y53 Sugiyama RPS21 QMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRLA
P63261 Y198 Sugiyama ACTG1 ACTG LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y362 Sugiyama ACTG1 ACTG GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67809 Y196 Sugiyama YBX1 NSEP1 YB1 sAPEGQAQQRRPyRRRRFPPyyMRRPYGRRPQysNPPVQGE
P67809 Y197 Sugiyama YBX1 NSEP1 YB1 APEGQAQQRRPyRRRRFPPyyMRRPYGRRPQysNPPVQGEV
P67809 Y208 Sugiyama YBX1 NSEP1 YB1 yRRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGE
P67809 Y72 Sugiyama YBX1 NSEP1 YB1 KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68104 Y254 Sugiyama EEF1A1 EEF1A EF1A LENG7 CILPPtRPTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKP
P68104 Y29 Sugiyama EEF1A1 EEF1A EF1A LENG7 NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 Y224 Sugiyama TUBA1B VDNEAIYDICRRNLDIERPtytNLNRLIsQIVSsITASLRF
P68363 Y432 Sugiyama TUBA1B GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
P68366 Y224 Sugiyama TUBA4A TUBA1 VDNEAIYDICRRNLDIERPtytNLNRLIsQIVSsITASLRF
P83731 Y11 Sugiyama RPL24 __________MKVELCsFsGyKIYPGHGRRYARTDGKVFQF
P84098 Y120 Sugiyama RPL19 RILRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILME
P84098 Y124 Sugiyama RPL19 RLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHIHK
P84103 Y13 Sugiyama SRSF3 SFRS3 SRP20 ________MHRDsCPLDCKVyVGNLGNNGNKtELERAFGyy
P84103 Y33 Sugiyama SRSF3 SFRS3 SRP20 yVGNLGNNGNKtELERAFGyyGPLRSVWVARNPPGFAFVEF
P98082 Y38 Sugiyama DAB2 DOC2 AAPKAPsKKEKKKGPEKTDEyLLARFKGDGVKYKAKLIGID
P98179 Y118 Sugiyama RBM3 RNPL GRGRSYSRGGGDQGYGSGRyyDsRPGGyGyGyGRSRDYNGR
Q00059 Y165 Sugiyama TFAM TCF6 TCF6L2 KKKELTLLGKPKRPRsAYNVyVAERFQEAKGDsPQEKLKTV
Q00526 Y15 Sugiyama CDK3 CDKN3 ______MDMFQKVEKIGEGtyGVVyKAKNRETGQLVALKKI
Q00610 Y883 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 EARIHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsR
Q00610 Y899 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 LAKIyIDsNNNPERFLRENPyyDsRVVGKYCEKRDPHLACV
Q00610 Y900 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 AKIyIDsNNNPERFLRENPyyDsRVVGKYCEKRDPHLACVA
Q00839 Y257 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 QKGGDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVE
Q00839 Y260 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED
Q01105 Y146 Sugiyama SET tEFEDIKsGyRIDFyFDENPyFENKVLSKEFHLNEsGDPss
Q01130 Y44 Sugiyama SRSF2 SFRS2 RtsPDtLRRVFEKYGRVGDVyIPRDRYTKESRGFAFVRFHD
Q01518 Y164 Sugiyama CAP1 CAP VAMAPKPGPYVKEMNDAAMFytNRVLKEYKDVDKKHVDWVK
Q02539 Y74 Sugiyama H1-1 H1F1 HIST1H1A SKERGGVSLAALKKALAAAGyDVEKNNSRIKLGIKsLVsKG
Q02543 Y63 Sugiyama RPL18A RFWYFVSQLKKMKKssGEIVyCGQVFEKsPLRVKNFGIWLR
Q02878 Y216 Sugiyama RPL6 TXREB1 AtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIFDtE
Q04837 Y73 Sugiyama SSBP1 SSBP PVTIFSLATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPG
Q05639 Y254 Sugiyama EEF1A2 EEF1AL STN TILPPTRPTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRP
Q05639 Y29 Sugiyama EEF1A2 EEF1AL STN NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
Q06187 Y223 SIGNOR|iPTMNet|EPSD|PSP BTK AGMX1 ATK BPK PPEPAAAPVSTSELKKVVALyDyMPMNANDLQLRKGDEYFI
Q06830 Y116 Sugiyama PRDX1 PAGA PAGB TDPX2 GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK
Q07157 Y669 Sugiyama TJP1 ZO1 IFGPIADVAREKLAREEPDIyQIAKSEPRDAGTDQRSsGII
Q07955 Y189 Sugiyama SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 TYAVRKLDNTKFRsHEGEtAyIRVKVDGPRsPsyGRsRsRs
Q07955 Y37 Sugiyama SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 RIyVGNLPPDIRtKDIEDVFyKYGAIRDIDLKNRRGGPPFA
Q08211 Y68 Sugiyama DHX9 DDX9 LKP NDH2 MGNSTNKKDAQSNAARDFVNyLVRINEIKsEEVPAFGVAsP
Q08881 S204 Sugiyama ITK EMT LYK TNDPQELALRRNEEyCLLDSsEIHWWRVQDRNGHEGyVPss
Q08881 S223 Sugiyama ITK EMT LYK SsEIHWWRVQDRNGHEGyVPssyLVEKSPNNLEtyEWyNKS
Q08881 S224 Sugiyama ITK EMT LYK sEIHWWRVQDRNGHEGyVPssyLVEKSPNNLEtyEWyNKSI
Q08881 S284 Sugiyama ITK EMT LYK VRDSRTAGTytVSVFTKAVVsENNPCIKHYHIKETNDNPKR
Q08881 S514 Sugiyama ITK EMT LYK QVIKVSDFGMTRFVLDDQytssTGtKFPVKWAsPEVFSFsR
Q08881 S526 Sugiyama ITK EMT LYK FVLDDQytssTGtKFPVKWAsPEVFSFsRYSSKSDVWSFGV
Q08881 S533 Sugiyama ITK EMT LYK tssTGtKFPVKWAsPEVFSFsRYSSKSDVWSFGVLMWEVFS
Q08881 S563 Sugiyama ITK EMT LYK SFGVLMWEVFSEGKIPYENRsNsEVVEDIsTGFRLYKPRLA
Q08881 S565 iPTMNet|EPSD|Sugiyama ITK EMT LYK GVLMWEVFSEGKIPYENRsNsEVVEDIsTGFRLYKPRLAST
Q08881 S572 Sugiyama ITK EMT LYK FSEGKIPYENRsNsEVVEDIsTGFRLYKPRLASTHVyQIMN
Q08881 S71 Sugiyama ITK EMT LYK LKGSIELSRIKCVEIVKSDIsIPCHyKYPFQVVHDNyLLyV
Q08881 T274 Sugiyama ITK EMT LYK LDTGKEGAFMVRDSRTAGTytVSVFTKAVVsENNPCIKHYH
Q08881 T513 Sugiyama ITK EMT LYK NQVIKVSDFGMTRFVLDDQytssTGtKFPVKWAsPEVFSFs
Q08881 Y120 Sugiyama ITK EMT LYK QRWVLALKEETRNNNSLVPKyHPNFWMDGKWRCCSQLEKLA
Q08881 Y146 Sugiyama ITK EMT LYK MDGKWRCCSQLEKLATGCAQyDPTKNASKKPLPPTPEDNRR
Q08881 Y180 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP ITK EMT LYK TPEDNRRPLWEPEETVVIALyDYQTNDPQELALRRNEEyCL
Q08881 Y198 Sugiyama ITK EMT LYK ALyDYQTNDPQELALRRNEEyCLLDSsEIHWWRVQDRNGHE
Q08881 Y220 Sugiyama ITK EMT LYK LLDSsEIHWWRVQDRNGHEGyVPssyLVEKSPNNLEtyEWy
Q08881 Y225 Sugiyama ITK EMT LYK EIHWWRVQDRNGHEGyVPssyLVEKSPNNLEtyEWyNKSIS
Q08881 Y237 Sugiyama ITK EMT LYK HEGyVPssyLVEKSPNNLEtyEWyNKSISRDKAEKLLLDTG
Q08881 Y240 Sugiyama ITK EMT LYK yVPssyLVEKSPNNLEtyEWyNKSISRDKAEKLLLDTGKEG
Q08881 Y273 Sugiyama ITK EMT LYK LLDTGKEGAFMVRDSRTAGTytVSVFTKAVVsENNPCIKHY
Q08881 Y336 Sugiyama ITK EMT LYK IPLLINYHQHNGGGLVTRLRyPVCFGRQKAPVTAGLRYGKW
Q08881 Y40 Sugiyama ITK EMT LYK RTSPSNFKVRFFVLTKASLAyFEDRHGKKRTLKGSIELSRI
Q08881 Y512 Sugiyama ITK EMT LYK ENQVIKVSDFGMTRFVLDDQytssTGtKFPVKWAsPEVFSF
Q08881 Y76 Sugiyama ITK EMT LYK ELSRIKCVEIVKSDIsIPCHyKYPFQVVHDNyLLyVFAPDR
Q08881 Y87 Sugiyama ITK EMT LYK KSDIsIPCHyKYPFQVVHDNyLLyVFAPDRESRQRWVLALK
Q08881 Y90 Sugiyama ITK EMT LYK IsIPCHyKYPFQVVHDNyLLyVFAPDRESRQRWVLALKEET
Q12965 Y971 Sugiyama MYO1E MYO1C PVRAAPPPPGyHQNGVIRNQyVPYPHAPGsQRSNQKSLyTs
Q12996 Y708 Sugiyama CSTF3 NEDsDEDEEKGAVVPPVHDIyRARQQKRIR___________
Q13094 Y173 EPSD|PSP LCP2 EEALQNSILPAKPFPNSNSMyIDRPPSGKTPQQPPVPPQRP
Q13242 Y152 Sugiyama SRSF9 SFRS9 SRP30C REAGDVCYADVQKDGVGMVEyLRKEDMEYALRKLDDTKFRs
Q13242 Y17 Sugiyama SRSF9 SFRS9 SRP30C ____MsGWADERGGEGDGRIyVGNLPTDVREKDLEDLFyKY
Q13263 Y133 Sugiyama TRIM28 KAP1 RNF96 TIF1B TVVDCPVCKQQCFSKDIVENyFMRDsGsKAATDAQDANQCC
Q13263 Y242 Sugiyama TRIM28 KAP1 RNF96 TIF1B ESCDTLTCRDCQLNAHKDHQyQFLEDAVRNQRKLLAsLVKR
Q13283 Y125 Sugiyama G3BP1 G3BP LRRFMQtFVLAPEGsVANKFyVHNDIFRyQDEVFGGFVtEP
Q13310 Y194 Sugiyama PABPC4 APP1 PABP4 KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF
Q13435 Y591 Sugiyama SF3B2 SAP145 LHDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSD
Q13435 Y592 Sugiyama SF3B2 SAP145 HDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSDE
Q13442 S19 Sugiyama PDAP1 HASPP28 __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE
Q13442 Y17 Sugiyama PDAP1 HASPP28 ____MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREE
Q13546 Y387 Sugiyama RIPK1 RIP RIP1 QEENEPSLQSKLQDEANyHLyGsRMDRQTKQQPRQNVAYNR
Q13561 S211 Sugiyama DCTN2 DCTN50 SGGKttGtPPDssLVtyELHsRPEQDKFSQAAKVAELEKRL
Q13561 Y207 Sugiyama DCTN2 DCTN50 SKGGSGGKttGtPPDssLVtyELHsRPEQDKFSQAAKVAEL
Q13561 Y6 Sugiyama DCTN2 DCTN50 _______________MADPKyADLPGIARNEPDVYETSDLP
Q13573 Y179 Sugiyama SNW1 SKIIP SKIP VAAAMPVRAADKLAPAQyIRytPsQQGVAFNsGAKQRVIRM
Q13601 Y287 Sugiyama KRR1 HRB2 tPFPPPQPESQIDKELAsGEyFLKANQKKRQKMEAIKAKQA
Q13765 Y120 Sugiyama NACA HSD48 KNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAAA
Q14004 Y399 Sugiyama CDK13 CDC2L CDC2L5 CHED KIAA1791 GGDVsPsPyssSsWRRsRsPysPVLRRSGKSRSRSPYSSRH
Q14152 Y697 Sugiyama EIF3A EIF3S10 KIAA0139 LEKEKKELQERLKNQEKKIDyFERAKRLEEIPLIKSAYEEQ
Q14240 Y71 Sugiyama EIF4A2 DDX2B EIF4F yGFEKPsAIQQRAIIPCIKGyDVIAQAQsGtGKTATFAISI
Q14247 Y421 Sugiyama CTTN EMS1 tPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVsGtE
Q14257 Y311 Sugiyama RCN2 ERC55 NPDLFLtsEAtDyGRQLHDDyFyHDEL______________
Q14257 Y313 Sugiyama RCN2 ERC55 DLFLtsEAtDyGRQLHDDyFyHDEL________________
Q14258 Y245 Sugiyama TRIM25 EFP RNF147 ZNF147 NRQQDVRMTANRKVEQLQQEytEMKALLDASETTSTRKIKE
Q14568 Y283 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI
Q14974 Y529 Sugiyama KPNB1 NTF97 KLLETTDRPDGHQNNLRSSAyEsLMEIVKNSAKDCYPAVQK
Q14980 Y1836 Sugiyama NUMA1 NMP22 NUMA NITMTKKLDVEEPDsANssFystRsAPAsQAsLRAtsstQs
Q14CX7 Y19 Sugiyama NAA25 C12orf30 MDM20 NAP1 __MATRGHVQDPNDRRLRPIyDyLDNGNNKMAIQQADKLLK
Q15024 Y13 Sugiyama EXOSC7 KIAA0116 RRP42 ________MASVTLSEAEKVyIVHGVQEDLRVDGRGCEDYR
Q15056 Y101 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 FKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRKQ
Q15293 Y115 Sugiyama RCN1 RCN GDGFVttEELKtWIKRVQKRyIFDNVAKVWKDYDRDKDDKI
Q15293 Y148 Sugiyama RCN1 RCN DRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFKKML
Q15293 Y278 Sugiyama RCN1 RCN LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE
Q15417 Y261 Sugiyama CNN3 STISLQMGTNKVAsQKGMsVyGLGRQVYDPKYCAAPTEPVI
Q15424 Y723 Sugiyama SAFB HAP HET SAFB1 EQERRPAVRRPYDLDRRDDAyWPEAKRAALDERYHSDFNRQ
Q15427 Y16 Sugiyama SF3B4 SAP49 _____MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFLQA
Q15459 Y456 Sugiyama SF3A1 SAP114 PRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAERRtDI
Q15527 Y123 Sugiyama SURF2 GRRYQRALCKYEECQKQGVEyVPACLVHRRRRREDQMDGDG
Q15631 Y210 Sugiyama TSN sLRKRYDGLKYDVKKVEEVVyDLSIRGFNKETAAACVEK__
Q15785 Y25 Sugiyama TOMM34 URCC3 FPDsVEELRAAGNESFRNGQyAEASALyGRALRVLQAQGss
Q15785 Y54 Sugiyama TOMM34 URCC3 RALRVLQAQGssDPEEEsVLysNRAACHLKDGNCRDCIKDC
Q16181 Y306 Sugiyama SEPTIN7 CDC10 SEPT7 RNMLIRTHMQDLKDVTNNVHyENyRSRKLAAVtyNGVDNNK
Q16719 S443 Sugiyama KYNU VVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAET
Q16719 Y441 Sugiyama KYNU RGVVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsA
Q16719 Y448 Sugiyama KYNU RNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAETKN___
Q16719 Y47 Sugiyama KYNU ERVALHLDEEDKLRHFRECFyIPKIQDLPPVDLSLVNKDEN
Q16778 Y38 Sugiyama H2BC21 H2BFQ HIST2H2BE AVTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssK
Q16778 Y41 Sugiyama H2BC21 H2BFQ HIST2H2BE KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKAMG
Q4VXU2 Y291 Sugiyama PABPC1L C20orf119 ERQNELKRRFEQMKQDRLRRyQGVNLyVKNLDDSIDDDKLR
Q4VXU2 Y297 Sugiyama PABPC1L C20orf119 KRRFEQMKQDRLRRyQGVNLyVKNLDDSIDDDKLRKEFSPY
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF6 Y167 Sugiyama HSP90AB4P GEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIGCL
Q58FF6 Y32 Sugiyama HSP90AB4P KEIFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDII
Q58FF7 Y171 Sugiyama HSP90AB3P HSP90BC GEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIGyP
Q58FF7 Y492 Sugiyama HSP90AB3P HSP90BC TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR
Q58FF7 Y56 Sugiyama HSP90AB3P HSP90BC EEIFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FF8 Y198 Sugiyama HSP90AB2P HSP90BB DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI
Q58FF8 Y260 Sugiyama HSP90AB2P HSP90BB VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW
Q58FF8 Y261 Sugiyama HSP90AB2P HSP90BB RYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVWK
Q58FF8 Y56 Sugiyama HSP90AB2P HSP90BB KEIFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FG0 Y177 Sugiyama HSP90AA5P HSP90AE GQLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQ
Q58FG0 Y178 Sugiyama HSP90AA5P HSP90AE QLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQK
Q5JTH9 Y1251 Sugiyama RRP12 KIAA0690 AEYKAKKAKGDVKKKGRPDPyAyIPLNRSKLNRRKKMKLQG
Q5JTH9 Y1253 Sugiyama RRP12 KIAA0690 YKAKKAKGDVKKKGRPDPyAyIPLNRSKLNRRKKMKLQGQF
Q5QNW6 Y38 Sugiyama H2BC18 HIST2H2BF AVTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q5QNW6 Y41 Sugiyama H2BC18 HIST2H2BF KVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q5QNW6 Y43 Sugiyama H2BC18 HIST2H2BF QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q5VTE0 Y254 Sugiyama EEF1A1P5 EEF1AL3 CILPPtRPTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKP
Q5VTE0 Y29 Sugiyama EEF1A1P5 EEF1AL3 NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
Q5VV41 Y216 Sugiyama ARHGEF16 EPHEXIN4 NBR KKTLGRKRGHKGsFKDDPQLyQEIQERGLNtsQEsDDDILD
Q6DN03 Y38 Sugiyama H2BC20P HIST2H2BC AVTKAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCK
Q6DN03 Y41 Sugiyama H2BC20P HIST2H2BC KAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMG
Q6DRA6 Y38 Sugiyama H2BC19P HIST2H2BD AVTKAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCK
Q6DRA6 Y41 Sugiyama H2BC19P HIST2H2BD KAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMG
Q6PEY2 Y224 Sugiyama TUBA3E VDNEAIYDICRRNLDIERPtytNLNRLIGQIVSSITASLRF
Q6PKG0 Y633 Sugiyama LARP1 KIAA0731 LARP MEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVtQtPHyM
Q6S8J3 Y1062 Sugiyama POTEE A26C1A POTE2 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6UB99 Y817 Sugiyama ANKRD11 ANCO1 EDKEKLKKEKVYREDsAFDEyCNKNQFLENEDtKFsLsDDQ
Q6UN15 Y454 Sugiyama FIP1L1 FIP1 RHE LPGSAPsWPSLVDTSKQWDyyARREKDRDRERDRDRERDRD
Q71RC2 Y425 Sugiyama LARP4 PP13296 SRNFPAERHNPTVTGHQEQtyLQKETSTLQVEQNGDYGRGR
Q71U36 Y224 Sugiyama TUBA1A TUBA3 VDNEAIYDICRRNLDIERPtytNLNRLIGQIVSSITASLRF
Q71U36 Y432 Sugiyama TUBA1A TUBA3 GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
Q7KZF4 Y476 Sugiyama SND1 TDRD11 SKGLATVIRYRQDDDQRssHyDELLAAEARAIKNGKGLHSK
Q7RTV0 Y100 Sugiyama PHF5A KDRDGCPKIVNLGSsKTDLFyERKKYGFKKR__________
Q86UK7 Y306 Sugiyama ZNF598 QFSYAPRHSRRNEGVVGGEDyEEVDRysRQGRVARAGTRGA
Q86V81 Y250 Sugiyama ALYREF ALY BEF THOC4 AGRNSKQQLsAEELDAQLDAyNARMDts_____________
Q86XP3 Y573 Sugiyama DDX42 VATDVAARGLDIPSIKTVINyDVARDIDTHTHRIGRTGRAG
Q8IXH6 Y211 Sugiyama TP53INP2 C20orf110 DOR PINH RQNRARESRPRRSKNQSsFIyQPCQRQFNY___________
Q8N0Y7 S137 Sugiyama PGAM4 PGAM3 RsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSYESPK
Q8N0Y7 Y133 Sugiyama PGAM4 PGAM3 KIWRRsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSY
Q8N0Y7 Y92 Sugiyama PGAM4 PGAM3 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
Q8N1G4 Y257 Sugiyama LRRC47 KIAA1185 LRDKRLEKMVSGCQTRSILEyLRVGGRGGGKGKGRAEGSEK
Q8N257 Y38 Sugiyama H2BC26 H2BU1 HIST3H2BB AVTKAQKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssK
Q8N257 Y41 Sugiyama H2BC26 H2BU1 HIST3H2BB KAQKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKAMG
Q8N5P1 Y97 Sugiyama ZC3H8 ZC3HDC8 sDNDICsQEsEDNFAKELQQyIQAREMANAAQPEESTKKEG
Q8NBS9 Y251 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 ALGLEHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDG
Q8NFD5 S1744 Sugiyama ARID1B BAF250B DAN15 KIAA1235 OSA2 ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI
Q8NI22 Y135 Sugiyama MCFD2 SDNSF DELINIIDGVLRDDDKNNDGyIDyAEFAKSLQ_________
Q8TDD1 Y681 Sugiyama DDX54 GPNRGAKRRREEARQRDQEFyIPyRPKDFDSERGLsIsGEG
Q8TDQ0 Y265 GPS6|SIGNOR|EPSD|PSP HAVCR2 TIM3 TIMD3 LPPSGLANAVAEGIRSEENIyTIEENVyEVEEPNEYYCYVS
Q8TEW0 S386 Sugiyama PARD3 PAR3 PAR3A YEQLSQSEKNNyyssRFsPDsQyIDNRSVNSAGLHTVQRAP
Q8TEW0 Y388 Sugiyama PARD3 PAR3 PAR3A QLSQSEKNNyyssRFsPDsQyIDNRSVNSAGLHTVQRAPRL
Q8WXX5 Y66 Sugiyama DNAJC9 RVGEGDKEDATRRFQILGKVySVLSDREQRAVYDEQGTVDE
Q8WYP5 Y1790 Sugiyama AHCTF1 ELYS TMBS62 MSTP108 QSVRKKTRKAKEISEASENIySDVRGLsQNQQIPQNsVtPR
Q92522 Y48 Sugiyama H1-10 H1FX AALsPsKKRKNSKKKNQPGKySQLVVEtIRRLGERNGSSLA
Q92598 Y641 Sugiyama HSPH1 HSP105 HSP110 KIAA0201 MIMQDKLEKERNDAKNAVEEyVyEFRDKLCGPYEKFICEQD
Q92598 Y643 Sugiyama HSPH1 HSP105 HSP110 KIAA0201 MQDKLEKERNDAKNAVEEyVyEFRDKLCGPYEKFICEQDHQ
Q93079 Y38 Sugiyama H2BC9 H2BFJ HIST1H2BH AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q93079 Y41 Sugiyama H2BC9 H2BFJ HIST1H2BH KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q93079 Y43 Sugiyama H2BC9 H2BFJ HIST1H2BH QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q969T4 Y91 Sugiyama UBE2E3 UBCE4 UBCH9 AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
Q96CT7 Y38 Sugiyama CCDC124 RRAEAKAAADAKKQKELEDAyWKDDDKHVMRKEQRKEEKEK
Q96DT5 T3057 Sugiyama DNAH11 HKDSISLFMAHVHTTVNEMStRYYQNERRHNYTTPKSFLEQ
Q96EU6 Y138 Sugiyama RRP36 C6orf153 HSPC253 RDPRFDDLSGEYNPEVFDKtyQFLNDIRAKEKELVKKQLKK
Q96F63 Y135 Sugiyama CCDC97 LREEHLACFGHVRGDHRADFyCAEVARQGTARPRTLRTRLR
Q96GX9 Y57 Sugiyama APIP CGI-29 HLGWVTGTGGGISLKHGDEIyIAPsGVQKERIQPEDMFVCD
Q96HN2 Y372 Sugiyama AHCYL2 KIAA0828 LCVPAMNVNDSVTKQKFDNLyCCRESILDGLKRTTDMMFGG
Q96LC7 Y597 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP SIGLEC10 SLG2 UNQ477/PRO940 RRTQTETPRPRFSRHstILDyINVVPTAGPLAQKRNQKATP
Q96LC7 Y667 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP SIGLEC10 SLG2 UNQ477/PRO940 PEPKSSTQAPESQESQEELHyATLNFPGVRPRPEARMPKGT
Q96LR5 Y85 Sugiyama UBE2E2 UBCH8 AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
Q96QK1 Y791 Sugiyama VPS35 MEM3 TCCCTA00141 HNtLEHLRLRREsPEsEGPIyEGLIL_______________
Q96T37 Y608 Sugiyama RBM15 OTT OTT1 PPPPPVRERSTRTAATsVPAyEPLDSLDRRRDGWsLDRDRG
Q99426 Y107 Sugiyama TBCB CG22 CKAP1 VIDHsGARLGEyEDVSRVEKytIsQEAyDQRQDtVRSFLKR
Q99426 Y114 Sugiyama TBCB CG22 CKAP1 RLGEyEDVSRVEKytIsQEAyDQRQDtVRSFLKRsKLGRyN
Q99460 Y494 Sugiyama PSMD1 RHGGSLGLGLAAMGTARQDVyDLLKTNLYQDDAVTGEAAGL
Q99497 S142 Sugiyama PARK7 KVTtHPLAKDKMMNGGHytysENRVEKDGLILtSRGPGTSF
Q99497 T140 Sugiyama PARK7 GSKVTtHPLAKDKMMNGGHytysENRVEKDGLILtSRGPGT
Q99497 Y139 Sugiyama PARK7 FGSKVTtHPLAKDKMMNGGHytysENRVEKDGLILtSRGPG
Q99497 Y141 Sugiyama PARK7 SKVTtHPLAKDKMMNGGHytysENRVEKDGLILtSRGPGTS
Q99543 S275 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 RAQRKKEEMNRIRtLVDNAysCDPRIKKFKEEEKAKKEAEK
Q99575 Y101 Sugiyama POP1 KIAA0061 FRKKGGWKAGPEGTsQEIPKyItAStFAQARAAEISAMLKA
Q99613 Y881 Sugiyama EIF3C EIF3S8 EKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMRR
Q99733 Y85 Sugiyama NAP1L4 NAP2 RRINALKQLQVRCAHIEAKFyEEVHDLERKyAALyQPLFDK
Q99733 Y95 Sugiyama NAP1L4 NAP2 VRCAHIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVE
Q99733 Y99 Sugiyama NAP1L4 NAP2 HIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVEPtDA
Q99848 Y265 Sugiyama EBNA1BP2 EBP2 NQKFGFGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPG
Q99877 Y38 Sugiyama H2BC15 H2BFD HIST1H2BN AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q99877 Y41 Sugiyama H2BC15 H2BFD HIST1H2BN KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99877 Y43 Sugiyama H2BC15 H2BFD HIST1H2BN QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q99879 Y38 Sugiyama H2BC14 H2BFE HIST1H2BM AINKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q99879 Y41 Sugiyama H2BC14 H2BFE HIST1H2BM KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99879 Y43 Sugiyama H2BC14 H2BFE HIST1H2BM QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q99880 Y38 Sugiyama H2BC13 H2BFC HIST1H2BL AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q99880 Y41 Sugiyama H2BC13 H2BFC HIST1H2BL KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99880 Y43 Sugiyama H2BC13 H2BFC HIST1H2BL QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q9BPX3 Y929 Sugiyama NCAPG CAPG NYMEL3 QDATLTTTTFQNEDEKNKEVyMtPLRGVKATQASKSTQLKT
Q9BQE3 Y224 Sugiyama TUBA1C TUBA6 VDNEAIYDICRRNLDIERPtytNLNRLIsQIVSsITASLRF
Q9BQE3 Y432 Sugiyama TUBA1C TUBA6 GMEEGEFSEAREDMAALEKDyEEVGADsADGEDEGEEy___
Q9BRD0 Y494 Sugiyama BUD13 KLERLEQRRKAEKDSERDELyAQWGKGLAQSRQQQQNVEDA
Q9BRK5 Y342 Sugiyama SDF4 CAB45 PSEC0034 MIAVADENQNHHLEPEEVLKysEFFTGSKLVDYARsVHEEF
Q9BRL6 Y44 Sugiyama SRSF8 SFRS2B SRP46 RtsPDsLRRVFEKYGRVGDVyIPREPHTKAPRGFAFVRFHD
Q9BS26 T398 Sugiyama ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 VASSPPESSFQKLAPsEyRytLLRDRDEL____________
Q9BS26 Y397 Sugiyama ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 DVASSPPESSFQKLAPsEyRytLLRDRDEL___________
Q9BS40 Y20 Sugiyama LXN _MEIPPTNYPASRAALVAQNyINyQQGTPHRVFEVQKVKQA
Q9BS40 Y23 Sugiyama LXN IPPTNYPASRAALVAQNyINyQQGTPHRVFEVQKVKQAsME
Q9BSU3 Y145 Sugiyama NAA11 ARD1B ARD2 TLNFQISEVEPKyyADGEDAyAMKRDLSQMADELRRQMDLK
Q9BUJ2 Y111 Sugiyama HNRNPUL1 E1BAP5 HNRPUL1 GYSGPDGHYAMDNITRQNQFyDtQVIKQENESGyERRPLEM
Q9BXS6 Y370 Sugiyama NUSAP1 ANKT BM-037 PRO0310 PVsNKKPVFDLKAsLsRPLNyEPHKGKLKPWGQSKENNyLN
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BYX7 Y362 Sugiyama POTEKP ACTBL3 FKSG30 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q9H4E7 Y210 EPSD|PSP DEF6 IBP SGRCLRGVGRDTLSMAIHEVyQELIQDVLKQGyLWKRGHLR
Q9H4E7 Y222 EPSD|PSP DEF6 IBP LSMAIHEVyQELIQDVLKQGyLWKRGHLRRNWAERWFQLQP
Q9H814 Y309 Sugiyama PHAX RNUXA FLNLLKNtPsISEEQIKDIFyIENQKEYENKKAARKRRTQV
Q9H9Y2 Y287 Sugiyama RPF1 BXDC5 FPHNPQFIGRQVATFHNQRDyIFFRFHRYIFRSEKKVGIQE
Q9HAP6 Y118 Sugiyama LIN7B MALS2 VELI2 UNQ3116/PRO10200 KTDEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLKRGD
Q9NRX4 Y113 Sugiyama PHPT1 PHP14 CGI-202 HSPC141 ysMAyGPAQHAISTEKIKAKyPDyEVtWANDGy________
Q9NUL3 Y326 Sugiyama STAU2 MNPISRLAQIQQAKKEKEPDyVLLSERGMPRRREFVMQVKV
Q9NUP9 Y118 Sugiyama LIN7C MALS3 VELI3 KTEEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLKRGD
Q9NVS9 Y195 Sugiyama PNPO SSVIPDREYLRKKNEELEQLyQDQEVPKPKSWGGYVLYPQV
Q9NVS9 Y256 Sugiyama PNPO LPtGDsPLGPMTHRGEEDWLyERLAP_______________
Q9NY65 Y224 Sugiyama TUBA8 TUBAL2 VDNEAIYDICRRNLDIERPtytNLNRLIsQIVSsITASLRF
Q9NYB9 T24 Sugiyama ABI2 ARGBPIA LQMLLEEEIPGGRRALFDsytNLERVADyCENNyIQSADKQ
Q9NYF8 Y219 Sugiyama BCLAF1 BTF KIAA0164 IDEFNKssAtsGDIWPGLsAyDNsPRsPHsPsPIAtPPSQS
Q9NZB2 Y9 Sugiyama FAM120A C9orf10 KIAA0183 OSSA ____________MGVQGFQDyIEKHCPsAVVPVELQKLARG
Q9UBR2 Y76 Sugiyama CTSZ YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA
Q9UBS4 Y74 Sugiyama DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080 PDRNPDDPQAQEKFQDLGAAyEVLsDSEKRKQyDTyGEEGL
Q9UHI6 Y659 Sugiyama DDX20 DP103 GEMIN3 RVPVLASSsQsGDsEsDSDSySSRTSSQSKGNKsyLEGssD
Q9UI15 Y192 Sugiyama TAGLN3 NP25 NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________
Q9UK59 Y533 Sugiyama DBR1 LsDEHEPEQRKKIKRRNQAIyAAVDDDDDDAA_________
Q9UKS6 Y206 Sugiyama PACSIN3 RKLQERVERCAKEAEKTKAQyEQtLAELHRYTPRYMEDMEQ
Q9UKV3 Y1086 Sugiyama ACIN1 ACINUS KIAA0670 RTALHGVKWPQSNPKFLCADyAEQDELDyHRGLLVDRPsEt
Q9UMX5 Y65 Sugiyama NENF CIR2 SPUF RLFtEEELARYGGEEEDQPIyLAVKGVVFDVtSGKEFYGRG
Q9UNZ2 Y167 Sugiyama NSFL1C UBXN2C PRPFAGGGYRLGAAPEEEsAyVAGEKRQHssQDVHVVLKLW
Q9UQ35 Y2693 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 RRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQSS
Q9Y230 Y172 Sugiyama RUVBL2 INO80J TIP48 TIP49B CGI-46 TGTGSKVGKLTLKTTEMETIyDLGTKMIESLTKDKVQAGDV
Q9Y265 Y438 Sugiyama RUVBL1 INO80H NMP238 TIP49 TIP49A KINGKDSIEKEHVEEIsELFyDAKSSAKILADQQDKYMK__
Q9Y281 T88 Sugiyama CFL2 YtsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPES
Q9Y281 Y85 Sugiyama CFL2 EDPYtsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWA
Q9Y281 Y89 Sugiyama CFL2 tsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPESA
Q9Y2T7 Y107 Sugiyama YBX2 CSDA3 MSY2 KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
Q9Y2W1 T230 Sugiyama THRAP3 BCLAF2 TRAP150 tsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERsPA
Q9Y2W1 Y228 Sugiyama THRAP3 BCLAF2 TRAP150 GGtsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERs
Q9Y3C1 Y118 Sugiyama NOP16 CGI-117 HSPC111 EAEASLPEKKGNTLSRDLIDyVRYMVENHGEDYKAMARDEK
Q9Y3D8 Y31 Sugiyama AK6 CINAP AD-004 CGI-137 TPGVGKTTLGKELASKSGLKyINVGDLAREEQLYDGYDEEY
Q9Y3F4 Y300 Sugiyama STRAP MAWD UNRIP yAsGSEDGTLRLWQTVVGKtyGLWKCVLPEEDsGELAKPKI
Q9Y3P9 Y472 Sugiyama RABGAP1 HSPC094 FFLKLKQIKQRERKNNTDTLyEVVCLESESERERRKTTAsP
Q9Y3U8 Y53 Sugiyama RPL36 LTKHTKFVRDMIREVCGFAPyERRAMELLKVSKDKRALKFI
Q9Y5Q8 Y393 Sugiyama GTF3C5 CDABP0017 SGtsGARKPASSKYKLKDSVyIFREGALPPYRQMFYQLCDL
Q9Y5R6 S43 Sugiyama DMRT1 DMT1 PPQGRAGGFGKASGALVGAAsGSSAGGSSRGGGSGSGASDL
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y5S9 Y54 Sugiyama RBM8A RBM8 HSPC114 MDS014 KRKGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWI
Q9Y696 Y244 Sugiyama CLIC4 AysRDEFtNtCPsDKEVEIAysDVAKRLTK___________
Site Promiscuity

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Signal Transduction R-HSA-162582 1.234550e-07 6.908 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.585516e-07 6.587 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.621140e-07 6.582 0 0
Axon guidance R-HSA-422475 2.474715e-06 5.606 0 0
Signaling by EGFR R-HSA-177929 6.152505e-06 5.211 0 0
Nervous system development R-HSA-9675108 6.297765e-06 5.201 0 0
Signaling by ERBB2 R-HSA-1227986 9.081478e-06 5.042 0 0
EPH-Ephrin signaling R-HSA-2682334 1.464303e-05 4.834 0 0
Cell-Cell communication R-HSA-1500931 1.472631e-05 4.832 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.919203e-05 4.535 0 0
Signaling by LTK R-HSA-9842663 2.804372e-05 4.552 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 4.457345e-05 4.351 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 5.743334e-05 4.241 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 9.109598e-05 4.041 0 0
GPVI-mediated activation cascade R-HSA-114604 1.021663e-04 3.991 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.021507e-04 3.991 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 9.753747e-05 4.011 0 0
ESR-mediated signaling R-HSA-8939211 9.827749e-05 4.008 0 0
Cell junction organization R-HSA-446728 8.401234e-05 4.076 0 0
Platelet activation, signaling and aggregation R-HSA-76002 7.404778e-05 4.130 0 0
IGF1R signaling cascade R-HSA-2428924 1.269363e-04 3.896 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 1.367092e-04 3.864 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.752033e-04 3.756 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.079223e-04 3.682 0 0
MET receptor recycling R-HSA-8875656 2.314084e-04 3.636 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 2.314084e-04 3.636 0 0
Apoptotic execution phase R-HSA-75153 2.909276e-04 3.536 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 3.060715e-04 3.514 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.761436e-04 3.425 0 0
Signaling by MET R-HSA-6806834 3.688722e-04 3.433 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.918382e-04 3.407 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.419102e-04 3.355 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 4.718129e-04 3.326 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 5.046217e-04 3.297 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 5.690185e-04 3.245 0 0
Developmental Biology R-HSA-1266738 6.072941e-04 3.217 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 6.108287e-04 3.214 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 6.852980e-04 3.164 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 7.604410e-04 3.119 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 7.604410e-04 3.119 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 7.604410e-04 3.119 0 0
Signaling by VEGF R-HSA-194138 7.604410e-04 3.119 0 0
Apoptosis R-HSA-109581 6.932987e-04 3.159 0 0
Integrin signaling R-HSA-354192 8.211247e-04 3.086 0 0
Signaling by Nuclear Receptors R-HSA-9006931 7.963514e-04 3.099 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 8.520823e-04 3.070 0 0
Formation of paraxial mesoderm R-HSA-9793380 8.739139e-04 3.059 0 0
Immune System R-HSA-168256 9.156089e-04 3.038 1 0
Transcriptional regulation by RUNX3 R-HSA-8878159 1.062245e-03 2.974 0 0
Adherens junctions interactions R-HSA-418990 1.011445e-03 2.995 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.045866e-03 2.981 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.045866e-03 2.981 0 0
HATs acetylate histones R-HSA-3214847 1.165795e-03 2.933 0 0
RET signaling R-HSA-8853659 1.174795e-03 2.930 0 0
MET activates PTPN11 R-HSA-8865999 1.322239e-03 2.879 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.336219e-03 2.874 0 0
MET promotes cell motility R-HSA-8875878 1.386481e-03 2.858 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.581488e-03 2.801 0 0
Interleukin-2 family signaling R-HSA-451927 1.623437e-03 2.790 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.730639e-03 2.762 0 0
Signaling by ALK in cancer R-HSA-9700206 1.730639e-03 2.762 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.751865e-03 2.756 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.890965e-03 2.723 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.029565e-03 2.693 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 2.061637e-03 2.686 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.114390e-03 2.675 0 0
RNA Polymerase I Transcription R-HSA-73864 2.280700e-03 2.642 0 0
G alpha (12/13) signalling events R-HSA-416482 2.280700e-03 2.642 0 0
DAP12 interactions R-HSA-2172127 2.336296e-03 2.631 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 2.501011e-03 2.602 0 0
Nucleosome assembly R-HSA-774815 2.501011e-03 2.602 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.673535e-03 2.573 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 2.501011e-03 2.602 0 0
Cell-cell junction organization R-HSA-421270 2.432808e-03 2.614 0 0
Programmed Cell Death R-HSA-5357801 2.787455e-03 2.555 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 2.886030e-03 2.540 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.027292e-03 2.519 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 3.039596e-03 2.517 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.042734e-03 2.517 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 3.315814e-03 2.479 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 3.315814e-03 2.479 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.694297e-03 2.432 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.058742e-03 2.392 0 0
Meiotic synapsis R-HSA-1221632 4.114854e-03 2.386 0 0
Sema4D in semaphorin signaling R-HSA-400685 4.444310e-03 2.352 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 4.851348e-03 2.314 0 0
NRAGE signals death through JNK R-HSA-193648 4.867243e-03 2.313 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 5.110336e-03 2.292 0 0
Packaging Of Telomere Ends R-HSA-171306 5.280185e-03 2.277 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 5.417060e-03 2.266 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 5.706913e-03 2.244 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 5.280185e-03 2.277 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 5.078550e-03 2.294 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 5.280185e-03 2.277 0 0
Estrogen-dependent gene expression R-HSA-9018519 5.855953e-03 2.232 0 0
DNA methylation R-HSA-5334118 6.204493e-03 2.207 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 6.204493e-03 2.207 0 0
Signaling by Erythropoietin R-HSA-9006335 6.204493e-03 2.207 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 6.204493e-03 2.207 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 6.204493e-03 2.207 0 0
Downstream signal transduction R-HSA-186763 7.219529e-03 2.141 0 0
Signaling by PDGF R-HSA-186797 6.638101e-03 2.178 0 0
DAP12 signaling R-HSA-2424491 6.700537e-03 2.174 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 6.700537e-03 2.174 0 0
Insulin receptor signalling cascade R-HSA-74751 7.311742e-03 2.136 0 0
EGFR downregulation R-HSA-182971 7.219529e-03 2.141 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 6.884388e-03 2.162 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 6.638101e-03 2.178 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 6.638101e-03 2.178 0 0
Response of endothelial cells to shear stress R-HSA-9860931 7.664437e-03 2.116 0 0
Signaling by WNT in cancer R-HSA-4791275 7.761717e-03 2.110 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 7.761717e-03 2.110 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 8.029006e-03 2.095 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 8.327331e-03 2.079 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 8.327331e-03 2.079 0 0
DNA Double Strand Break Response R-HSA-5693606 8.404343e-03 2.075 0 0
Regulation of CDH11 function R-HSA-9762292 8.460846e-03 2.073 0 0
Adaptive Immune System R-HSA-1280218 8.670040e-03 2.062 1 0
Deletions in the AMER1 gene destabilize the destruction complex R-HSA-5467343 1.044038e-02 1.981 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.044038e-02 1.981 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 9.745723e-03 2.011 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 9.745723e-03 2.011 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 9.529687e-03 2.021 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 1.016682e-02 1.993 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 1.016682e-02 1.993 0 0
Cell Cycle, Mitotic R-HSA-69278 9.411235e-03 2.026 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 9.529687e-03 2.021 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 9.598779e-03 2.018 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.529687e-03 2.021 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.045337e-02 1.981 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.077935e-02 1.967 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.082815e-02 1.965 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.089852e-02 1.963 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.105027e-02 1.957 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.111153e-02 1.954 0 0
Signaling by AMER1 mutants R-HSA-4839748 1.111153e-02 1.954 0 0
Signaling by GSK3beta mutants R-HSA-5339716 1.111153e-02 1.954 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.151385e-02 1.939 0 0
Cleavage of the damaged purine R-HSA-110331 1.151385e-02 1.939 0 0
Depurination R-HSA-73927 1.222405e-02 1.913 0 0
MET activates RAS signaling R-HSA-8851805 1.255646e-02 1.901 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 1.255646e-02 1.901 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 1.255646e-02 1.901 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 1.255646e-02 1.901 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 1.255646e-02 1.901 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 1.255646e-02 1.901 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.371851e-02 1.863 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.450299e-02 1.839 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 1.255646e-02 1.901 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.255646e-02 1.901 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.371851e-02 1.863 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 1.450299e-02 1.839 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.531243e-02 1.815 0 0
Interleukin-15 signaling R-HSA-8983432 1.255646e-02 1.901 0 0
Mitotic Prophase R-HSA-68875 1.407374e-02 1.852 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.533790e-02 1.814 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.533790e-02 1.814 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 1.546090e-02 1.811 0 0
MAPK family signaling cascades R-HSA-5683057 1.606548e-02 1.794 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.614692e-02 1.792 0 0
Depyrimidination R-HSA-73928 1.614692e-02 1.792 0 0
Ub-specific processing proteases R-HSA-5689880 1.645613e-02 1.784 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.700342e-02 1.769 0 0
Defective pyroptosis R-HSA-9710421 1.700653e-02 1.769 0 0
Signaling by FGFR4 R-HSA-5654743 1.700653e-02 1.769 0 0
Activation and oligomerization of BAK protein R-HSA-111452 2.077240e-02 1.683 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 2.077240e-02 1.683 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.734832e-02 1.761 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 1.734832e-02 1.761 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.909221e-02 1.719 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.278984e-02 1.642 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 2.278984e-02 1.642 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 2.090660e-02 1.680 0 0
Meiosis R-HSA-1500620 1.721201e-02 1.764 0 0
Cyclin D associated events in G1 R-HSA-69231 1.789133e-02 1.747 0 0
G1 Phase R-HSA-69236 1.789133e-02 1.747 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.278984e-02 1.642 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.278984e-02 1.642 0 0
Somitogenesis R-HSA-9824272 1.880136e-02 1.726 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.882987e-02 1.725 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.168320e-02 1.664 0 0
Cell Cycle R-HSA-1640170 2.209254e-02 1.656 0 0
Signaling by FGFR3 R-HSA-5654741 1.880136e-02 1.726 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 1.909221e-02 1.719 0 0
Signaling by NOTCH R-HSA-157118 2.063668e-02 1.685 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.734832e-02 1.761 0 0
GPER1 signaling R-HSA-9634597 2.168320e-02 1.664 0 0
Diseases of programmed cell death R-HSA-9645723 1.973261e-02 1.705 0 0
Signaling by Hippo R-HSA-2028269 2.278984e-02 1.642 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 2.090660e-02 1.680 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.907449e-02 1.720 0 0
Disease R-HSA-1643685 1.968795e-02 1.706 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.914743e-02 1.718 0 0
Signaling by Insulin receptor R-HSA-74752 2.318859e-02 1.635 0 0
PI3K Cascade R-HSA-109704 2.373106e-02 1.625 0 0
Assembly of the pre-replicative complex R-HSA-68867 2.392113e-02 1.621 0 0
Ephrin signaling R-HSA-3928664 2.474031e-02 1.607 0 0
GAB1 signalosome R-HSA-180292 2.474031e-02 1.607 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.474031e-02 1.607 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.474031e-02 1.607 0 0
Tie2 Signaling R-HSA-210993 2.474031e-02 1.607 0 0
Meiotic recombination R-HSA-912446 2.479299e-02 1.606 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 2.588022e-02 1.587 0 0
Innate Immune System R-HSA-168249 2.627228e-02 1.581 1 0
Deubiquitination R-HSA-5688426 2.689705e-02 1.570 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 2.699090e-02 1.569 0 0
M Phase R-HSA-68886 2.726017e-02 1.564 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 2.813049e-02 1.551 0 0
Negative regulation of MET activity R-HSA-6807004 2.883662e-02 1.540 0 0
HDACs deacetylate histones R-HSA-3214815 2.929345e-02 1.533 0 0
FOXO-mediated transcription R-HSA-9614085 2.944109e-02 1.531 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 2.944109e-02 1.531 0 0
Signaling by FGFR1 R-HSA-5654736 3.048156e-02 1.516 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 3.058295e-02 1.515 1 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 3.097936e-02 1.509 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 3.097936e-02 1.509 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 3.097936e-02 1.509 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.097936e-02 1.509 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5660686 3.099717e-02 1.509 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5619101 3.099717e-02 1.509 0 0
Inhibition of membrane repair R-HSA-9635644 3.099717e-02 1.509 0 0
Signaling by NTRKs R-HSA-166520 3.158718e-02 1.500 0 0
Dectin-2 family R-HSA-5621480 3.169477e-02 1.499 0 0
IRS-mediated signalling R-HSA-112399 3.169477e-02 1.499 0 0
Gastrulation R-HSA-9758941 3.228565e-02 1.491 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 3.318311e-02 1.479 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.318311e-02 1.479 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 3.318311e-02 1.479 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 4.014570e-02 1.396 0 0
MET activates PTK2 signaling R-HSA-8874081 4.506582e-02 1.346 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 4.760522e-02 1.322 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 4.971051e-02 1.304 0 0
FCERI mediated MAPK activation R-HSA-2871796 4.257604e-02 1.371 0 0
Myogenesis R-HSA-525793 4.506582e-02 1.346 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 4.971051e-02 1.304 0 0
Notch-HLH transcription pathway R-HSA-350054 3.544639e-02 1.450 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 3.548426e-02 1.450 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 4.014570e-02 1.396 0 0
TCR signaling R-HSA-202403 4.052707e-02 1.392 1 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 4.795044e-02 1.319 1 1
Gene Silencing by RNA R-HSA-211000 3.756168e-02 1.425 0 0
Signaling by EGFR in Cancer R-HSA-1643713 4.506582e-02 1.346 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 4.014570e-02 1.396 0 0
Death Receptor Signaling R-HSA-73887 3.592266e-02 1.445 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 4.760522e-02 1.322 0 0
Intracellular signaling by second messengers R-HSA-9006925 3.822955e-02 1.418 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 5.019568e-02 1.299 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 3.679710e-02 1.434 0 0
Semaphorin interactions R-HSA-373755 3.949677e-02 1.403 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 4.971051e-02 1.304 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 3.949677e-02 1.403 0 0
Signaling by PTK6 R-HSA-8848021 3.949677e-02 1.403 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 4.760522e-02 1.322 0 0
Hemostasis R-HSA-109582 4.497872e-02 1.347 0 0
SARS-CoV-1-host interactions R-HSA-9692914 3.660201e-02 1.436 0 0
DNA Replication Pre-Initiation R-HSA-69002 3.952420e-02 1.403 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 4.506582e-02 1.346 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.548426e-02 1.450 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 4.468263e-02 1.350 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 4.863431e-02 1.313 0 0
MET interacts with TNS proteins R-HSA-8875513 5.112940e-02 1.291 0 0
MET activates STAT3 R-HSA-8875791 5.112940e-02 1.291 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 5.126503e-02 1.290 0 0
Homology Directed Repair R-HSA-5693538 5.134747e-02 1.289 0 0
Signaling by WNT R-HSA-195721 5.167049e-02 1.287 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 5.198398e-02 1.284 0 0
Chromatin modifying enzymes R-HSA-3247509 5.257030e-02 1.279 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 5.283590e-02 1.277 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 5.388359e-02 1.269 0 0
SARS-CoV-1 Infection R-HSA-9678108 5.484840e-02 1.261 0 0
Chromosome Maintenance R-HSA-73886 5.487321e-02 1.261 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 5.552456e-02 1.256 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 5.552456e-02 1.256 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 5.552456e-02 1.256 0 0
Interleukin-37 signaling R-HSA-9008059 5.552456e-02 1.256 0 0
Signaling by FGFR in disease R-HSA-1226099 5.606853e-02 1.251 0 0
G2/M DNA damage checkpoint R-HSA-69473 5.606853e-02 1.251 0 0
RNA Polymerase II Transcription R-HSA-73857 5.738288e-02 1.241 0 0
Protein ubiquitination R-HSA-8852135 5.771581e-02 1.239 0 0
Cellular Senescence R-HSA-2559583 5.982237e-02 1.223 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 6.103903e-02 1.214 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 6.103903e-02 1.214 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 6.103903e-02 1.214 0 0
Regulation of gap junction activity R-HSA-191650 6.103903e-02 1.214 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 6.103903e-02 1.214 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 6.103903e-02 1.214 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 6.103903e-02 1.214 0 0
G0 and Early G1 R-HSA-1538133 6.104207e-02 1.214 0 0
Diseases of mitotic cell cycle R-HSA-9675126 6.104207e-02 1.214 0 0
TCF dependent signaling in response to WNT R-HSA-201681 6.292657e-02 1.201 0 0
Platelet degranulation R-HSA-114608 6.359632e-02 1.197 0 0
FGFR1 mutant receptor activation R-HSA-1839124 6.386841e-02 1.195 0 0
Cardiogenesis R-HSA-9733709 6.386841e-02 1.195 0 0
Cellular responses to stimuli R-HSA-8953897 6.504156e-02 1.187 0 0
Generic Transcription Pathway R-HSA-212436 6.523526e-02 1.186 0 0
Chromatin organization R-HSA-4839726 6.551772e-02 1.184 0 0
Neutrophil degranulation R-HSA-6798695 6.622335e-02 1.179 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 6.629043e-02 1.179 0 0
Signaling by FGFR2 R-HSA-5654738 6.629043e-02 1.179 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 6.629043e-02 1.179 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 6.673818e-02 1.176 0 0
Processing of DNA double-strand break ends R-HSA-5693607 6.807175e-02 1.167 0 0
Amyloid fiber formation R-HSA-977225 6.807175e-02 1.167 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 7.084578e-02 1.150 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 7.084578e-02 1.150 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 7.084578e-02 1.150 0 0
Defective CSF2RA causes SMDP4 R-HSA-5688890 8.055070e-02 1.094 0 0
Defective CSF2RB causes SMDP5 R-HSA-5688849 8.055070e-02 1.094 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 9.015485e-02 1.045 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 9.015485e-02 1.045 0 0
STAT5 Activation R-HSA-9645135 9.015485e-02 1.045 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 9.965926e-02 1.001 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 9.965926e-02 1.001 0 0
TRIF-mediated programmed cell death R-HSA-2562578 9.965926e-02 1.001 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.090650e-01 0.962 0 0
Type I hemidesmosome assembly R-HSA-446107 1.090650e-01 0.962 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 1.090650e-01 0.962 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 1.090650e-01 0.962 0 0
ARMS-mediated activation R-HSA-170984 1.183730e-01 0.927 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 1.183730e-01 0.927 0 0
Interleukin-21 signaling R-HSA-9020958 1.183730e-01 0.927 0 0
CASP8 activity is inhibited R-HSA-5218900 1.183730e-01 0.927 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 1.275844e-01 0.894 0 0
PECAM1 interactions R-HSA-210990 1.367000e-01 0.864 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 1.367000e-01 0.864 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 1.367000e-01 0.864 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 1.367000e-01 0.864 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 1.367000e-01 0.864 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 1.367000e-01 0.864 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 6.965018e-02 1.157 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 9.756940e-02 1.011 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 1.350737e-01 0.869 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.306601e-01 0.884 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.330146e-01 0.876 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 8.704548e-02 1.060 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 9.965926e-02 1.001 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 9.111947e-02 1.040 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 7.084578e-02 1.150 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 8.055070e-02 1.094 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.041444e-01 0.982 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.168577e-01 0.932 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 1.090650e-01 0.962 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.236879e-01 0.908 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.236879e-01 0.908 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.123863e-01 0.949 0 0
Activation of AKT2 R-HSA-165158 7.084578e-02 1.150 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 7.084578e-02 1.150 0 0
mRNA 3'-end processing R-HSA-72187 1.315408e-01 0.881 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.330146e-01 0.876 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.210777e-01 0.917 0 0
MET Receptor Activation R-HSA-6806942 9.015485e-02 1.045 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 7.084578e-02 1.150 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 8.055070e-02 1.094 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 8.055070e-02 1.094 0 0
Regulation by c-FLIP R-HSA-3371378 1.090650e-01 0.962 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 1.275844e-01 0.894 0 0
Signaling by APC mutants R-HSA-4839744 1.367000e-01 0.864 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 9.965926e-02 1.001 0 0
Signal attenuation R-HSA-74749 1.275844e-01 0.894 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 7.354509e-02 1.133 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 9.965926e-02 1.001 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 9.538379e-02 1.021 0 0
Co-inhibition by PD-1 R-HSA-389948 8.219940e-02 1.085 0 0
Signalling to ERKs R-HSA-187687 7.260321e-02 1.139 0 0
Dimerization of procaspase-8 R-HSA-69416 1.090650e-01 0.962 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.183730e-01 0.927 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.367000e-01 0.864 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.068141e-01 0.971 0 0
Degradation of CDH1 R-HSA-9766229 1.210777e-01 0.917 0 0
Parasite infection R-HSA-9664407 8.457162e-02 1.073 0 0
Leishmania phagocytosis R-HSA-9664417 8.457162e-02 1.073 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 8.457162e-02 1.073 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.607738e-02 1.065 0 0
Signaling by FGFR R-HSA-190236 1.079827e-01 0.967 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 9.015485e-02 1.045 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 7.214709e-02 1.142 0 0
RSK activation R-HSA-444257 1.090650e-01 0.962 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.315408e-01 0.881 0 0
Gene expression (Transcription) R-HSA-74160 9.765988e-02 1.010 0 0
Generation of second messenger molecules R-HSA-202433 8.794394e-02 1.056 1 1
Transcriptional Regulation by VENTX R-HSA-8853884 9.111947e-02 1.040 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 7.260321e-02 1.139 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 7.300387e-02 1.137 0 0
Neurexins and neuroligins R-HSA-6794361 1.315408e-01 0.881 0 0
FLT3 Signaling R-HSA-9607240 9.111947e-02 1.040 0 0
RUNX2 regulates bone development R-HSA-8941326 7.559611e-02 1.122 0 0
Reproduction R-HSA-1474165 6.888923e-02 1.162 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 9.756940e-02 1.011 0 0
Telomere Maintenance R-HSA-157579 1.058069e-01 0.975 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.275844e-01 0.894 0 0
Signaling by SCF-KIT R-HSA-1433557 1.008418e-01 0.996 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.168577e-01 0.932 0 0
Cell Cycle Checkpoints R-HSA-69620 7.410976e-02 1.130 0 0
Interleukin-2 signaling R-HSA-9020558 1.367000e-01 0.864 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 8.905441e-02 1.050 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.183730e-01 0.927 0 0
Signaling by ROBO receptors R-HSA-376176 8.589335e-02 1.066 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.018415e-01 0.992 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 7.260321e-02 1.139 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 8.169701e-02 1.088 0 0
Base Excision Repair R-HSA-73884 8.704548e-02 1.060 0 0
DNA Replication R-HSA-69306 1.068141e-01 0.971 0 0
Signaling by ALK R-HSA-201556 8.480276e-02 1.072 0 0
Translation initiation complex formation R-HSA-72649 1.386278e-01 0.858 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.407231e-01 0.852 0 0
Signaling by NOTCH3 R-HSA-9012852 1.422023e-01 0.847 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 1.457210e-01 0.836 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.457210e-01 0.836 0 0
Signaling by AXIN mutants R-HSA-4839735 1.457210e-01 0.836 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.457963e-01 0.836 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 1.457963e-01 0.836 0 0
Regulation of CDH1 Function R-HSA-9764561 1.494092e-01 0.826 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.494092e-01 0.826 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.530400e-01 0.815 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.546483e-01 0.811 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.546483e-01 0.811 0 0
Diseases associated with surfactant metabolism R-HSA-5687613 1.546483e-01 0.811 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.546483e-01 0.811 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.546483e-01 0.811 0 0
Regulation of beta-cell development R-HSA-186712 1.566881e-01 0.805 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.573366e-01 0.803 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.573366e-01 0.803 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.603527e-01 0.795 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.603527e-01 0.795 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.603527e-01 0.795 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.603527e-01 0.795 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.603527e-01 0.795 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.634828e-01 0.787 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.634828e-01 0.787 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.634828e-01 0.787 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.634828e-01 0.787 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.634828e-01 0.787 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.634828e-01 0.787 0 0
Formation of axial mesoderm R-HSA-9796292 1.634828e-01 0.787 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 1.634828e-01 0.787 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 1.634828e-01 0.787 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.640331e-01 0.785 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 1.648872e-01 0.783 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.714382e-01 0.766 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.714382e-01 0.766 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.722255e-01 0.764 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 1.722255e-01 0.764 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 1.722255e-01 0.764 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 1.722255e-01 0.764 0 0
Signaling by FGFR4 in disease R-HSA-5655291 1.722255e-01 0.764 0 0
Physiological factors R-HSA-5578768 1.722255e-01 0.764 0 0
Signal regulatory protein family interactions R-HSA-391160 1.722255e-01 0.764 0 0
Prolactin receptor signaling R-HSA-1170546 1.722255e-01 0.764 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 1.722255e-01 0.764 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.767245e-01 0.753 0 0
Cilium Assembly R-HSA-5617833 1.783195e-01 0.749 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 1.808774e-01 0.743 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.808774e-01 0.743 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 1.808774e-01 0.743 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.808774e-01 0.743 0 0
DCC mediated attractive signaling R-HSA-418885 1.808774e-01 0.743 0 0
Erythropoietin activates RAS R-HSA-9027284 1.808774e-01 0.743 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.808774e-01 0.743 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.808774e-01 0.743 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.808774e-01 0.743 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.808774e-01 0.743 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.826465e-01 0.738 0 0
G2/M Checkpoints R-HSA-69481 1.881494e-01 0.725 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.894394e-01 0.723 0 0
Phosphorylation of the APC/C R-HSA-176412 1.894394e-01 0.723 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.894394e-01 0.723 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 1.894394e-01 0.723 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 1.894394e-01 0.723 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 1.894394e-01 0.723 0 0
Prolonged ERK activation events R-HSA-169893 1.894394e-01 0.723 0 0
Negative regulation of FLT3 R-HSA-9706369 1.894394e-01 0.723 0 0
Differentiation of T cells R-HSA-9945266 1.894394e-01 0.723 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 1.894394e-01 0.723 0 0
Regulated Necrosis R-HSA-5218859 1.901779e-01 0.721 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 1.977507e-01 0.704 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 1.979125e-01 0.704 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 1.979125e-01 0.704 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 1.979125e-01 0.704 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 1.979125e-01 0.704 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.979125e-01 0.704 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 1.979125e-01 0.704 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 2.015510e-01 0.696 0 0
Regulation of mitotic cell cycle R-HSA-453276 2.015510e-01 0.696 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 2.053599e-01 0.687 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 2.053599e-01 0.687 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 2.053599e-01 0.687 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 2.062975e-01 0.686 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 2.062975e-01 0.686 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 2.062975e-01 0.686 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 2.062975e-01 0.686 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.070036e-01 0.684 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.091767e-01 0.679 0 0
Ca2+ pathway R-HSA-4086398 2.091767e-01 0.679 0 0
Parasitic Infection Pathways R-HSA-9824443 2.107091e-01 0.676 0 0
Leishmania infection R-HSA-9658195 2.107091e-01 0.676 0 0
Signaling by ERBB4 R-HSA-1236394 2.130008e-01 0.672 0 0
Signaling by NOTCH4 R-HSA-9013694 2.130008e-01 0.672 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.145953e-01 0.668 0 0
Platelet sensitization by LDL R-HSA-432142 2.145953e-01 0.668 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 2.145953e-01 0.668 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.145953e-01 0.668 0 0
Apoptotic factor-mediated response R-HSA-111471 2.145953e-01 0.668 0 0
Centrosome maturation R-HSA-380287 2.168317e-01 0.664 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.168317e-01 0.664 0 0
Signaling by NOTCH1 R-HSA-1980143 2.206689e-01 0.656 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 2.228069e-01 0.652 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.228069e-01 0.652 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 2.228069e-01 0.652 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.228069e-01 0.652 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.228069e-01 0.652 0 0
Specification of the neural plate border R-HSA-9834899 2.228069e-01 0.652 0 0
Regulation of signaling by CBL R-HSA-912631 2.228069e-01 0.652 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.228069e-01 0.652 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 2.228069e-01 0.652 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.258369e-01 0.646 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 2.299403e-01 0.638 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 2.309331e-01 0.637 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 2.309331e-01 0.637 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 2.309331e-01 0.637 0 0
Nephrin family interactions R-HSA-373753 2.309331e-01 0.637 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.309331e-01 0.637 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 2.309331e-01 0.637 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 2.309331e-01 0.637 0 0
Creatine metabolism R-HSA-71288 2.309331e-01 0.637 0 0
Formation of definitive endoderm R-HSA-9823730 2.309331e-01 0.637 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 2.389749e-01 0.622 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.389749e-01 0.622 0 0
Signalling to RAS R-HSA-167044 2.389749e-01 0.622 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 2.389749e-01 0.622 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 2.389749e-01 0.622 0 0
Signaling by Interleukins R-HSA-449147 2.394841e-01 0.621 0 0
S Phase R-HSA-69242 2.535866e-01 0.596 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 2.548085e-01 0.594 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 2.548085e-01 0.594 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 2.548085e-01 0.594 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.548085e-01 0.594 0 0
Protein-protein interactions at synapses R-HSA-6794362 2.553970e-01 0.593 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.592682e-01 0.586 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.592682e-01 0.586 0 0
Termination of O-glycan biosynthesis R-HSA-977068 2.626021e-01 0.581 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 2.626021e-01 0.581 0 0
Growth hormone receptor signaling R-HSA-982772 2.626021e-01 0.581 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 2.626021e-01 0.581 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 2.626021e-01 0.581 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.626021e-01 0.581 0 0
XBP1(S) activates chaperone genes R-HSA-381038 2.631402e-01 0.580 0 0
Post NMDA receptor activation events R-HSA-438064 2.670126e-01 0.573 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.703146e-01 0.568 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 2.703146e-01 0.568 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.703146e-01 0.568 0 0
Deadenylation of mRNA R-HSA-429947 2.703146e-01 0.568 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.708849e-01 0.567 0 0
Peptide chain elongation R-HSA-156902 2.708849e-01 0.567 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 2.779470e-01 0.556 0 0
TGFBR3 expression R-HSA-9839394 2.779470e-01 0.556 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 2.779470e-01 0.556 0 0
Formation of the nephric duct R-HSA-9830364 2.779470e-01 0.556 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.779470e-01 0.556 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 2.824972e-01 0.549 0 0
Cell surface interactions at the vascular wall R-HSA-202733 2.847461e-01 0.546 0 0
TRP channels R-HSA-3295583 2.854999e-01 0.544 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 2.854999e-01 0.544 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.854999e-01 0.544 0 0
Metalloprotease DUBs R-HSA-5689901 2.854999e-01 0.544 0 0
Suppression of phagosomal maturation R-HSA-9637687 2.854999e-01 0.544 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 2.863652e-01 0.543 0 0
IRE1alpha activates chaperones R-HSA-381070 2.863652e-01 0.543 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.902311e-01 0.537 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 2.929744e-01 0.533 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 2.929744e-01 0.533 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 2.929744e-01 0.533 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 2.929744e-01 0.533 0 0
Signaling by FGFR3 in disease R-HSA-5655332 2.929744e-01 0.533 0 0
Triglyceride biosynthesis R-HSA-75109 2.929744e-01 0.533 0 0
Synthesis of PE R-HSA-1483213 2.929744e-01 0.533 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 2.940945e-01 0.532 0 0
Cellular responses to stress R-HSA-2262752 2.968034e-01 0.528 0 0
Separation of Sister Chromatids R-HSA-2467813 2.988599e-01 0.525 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 3.003711e-01 0.522 0 0
Pyroptosis R-HSA-5620971 3.003711e-01 0.522 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 3.018126e-01 0.520 0 0
Formation of a pool of free 40S subunits R-HSA-72689 3.056665e-01 0.515 0 0
Eukaryotic Translation Termination R-HSA-72764 3.056665e-01 0.515 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 3.076908e-01 0.512 0 0
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174 3.076908e-01 0.512 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 3.095165e-01 0.509 0 0
Activation of BH3-only proteins R-HSA-114452 3.149345e-01 0.502 0 0
G alpha (s) signalling events R-HSA-418555 3.216972e-01 0.493 0 0
Cargo concentration in the ER R-HSA-5694530 3.221027e-01 0.492 0 0
Selenocysteine synthesis R-HSA-2408557 3.286971e-01 0.483 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.325171e-01 0.478 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.362164e-01 0.473 0 0
Regulation of necroptotic cell death R-HSA-5675482 3.362164e-01 0.473 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.362164e-01 0.473 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 3.362164e-01 0.473 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 3.362164e-01 0.473 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.362164e-01 0.473 0 0
G-protein beta:gamma signalling R-HSA-397795 3.362164e-01 0.473 0 0
Viral mRNA Translation R-HSA-192823 3.363310e-01 0.473 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.401385e-01 0.468 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 3.401385e-01 0.468 0 0
Infectious disease R-HSA-5663205 3.408139e-01 0.467 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.431633e-01 0.464 0 0
Dual Incision in GG-NER R-HSA-5696400 3.500379e-01 0.456 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.500379e-01 0.456 0 0
PERK regulates gene expression R-HSA-381042 3.568410e-01 0.448 0 0
Oncogene Induced Senescence R-HSA-2559585 3.568410e-01 0.448 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.590708e-01 0.445 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.628344e-01 0.440 0 0
FLT3 signaling in disease R-HSA-9682385 3.635733e-01 0.439 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 3.635733e-01 0.439 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 3.635733e-01 0.439 0 0
G1/S-Specific Transcription R-HSA-69205 3.635733e-01 0.439 0 0
Regulation of TP53 Degradation R-HSA-6804757 3.635733e-01 0.439 0 0
G2/M Transition R-HSA-69275 3.645032e-01 0.438 0 0
DNA Repair R-HSA-73894 3.687964e-01 0.433 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.701880e-01 0.432 0 0
Voltage gated Potassium channels R-HSA-1296072 3.702355e-01 0.432 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.702355e-01 0.432 0 0
Ovarian tumor domain proteases R-HSA-5689896 3.702355e-01 0.432 0 0
SLC-mediated transport of organic cations R-HSA-549127 3.702355e-01 0.432 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 3.740749e-01 0.427 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 3.740749e-01 0.427 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 3.768284e-01 0.424 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 3.833527e-01 0.416 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 3.833527e-01 0.416 0 0
Mitotic Prometaphase R-HSA-68877 3.843589e-01 0.415 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.871849e-01 0.412 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 3.898091e-01 0.409 0 0
Interferon alpha/beta signaling R-HSA-909733 3.926281e-01 0.406 0 0
HCMV Early Events R-HSA-9609690 3.928281e-01 0.406 0 0
SARS-CoV Infections R-HSA-9679506 4.010539e-01 0.397 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 4.025209e-01 0.395 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 4.087778e-01 0.389 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.145613e-01 0.382 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 4.149695e-01 0.382 0 0
Response of Mtb to phagocytosis R-HSA-9637690 4.149695e-01 0.382 0 0
mRNA Splicing R-HSA-72172 4.180488e-01 0.379 0 0
Netrin-1 signaling R-HSA-373752 4.210967e-01 0.376 0 0
Surfactant metabolism R-HSA-5683826 4.210967e-01 0.376 0 0
Formation of the cornified envelope R-HSA-6809371 4.253811e-01 0.371 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.271602e-01 0.369 0 0
G1/S Transition R-HSA-69206 4.325369e-01 0.364 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.331605e-01 0.363 0 0
Regulation of TNFR1 signaling R-HSA-5357905 4.331605e-01 0.363 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 4.331605e-01 0.363 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.331605e-01 0.363 0 0
Signaling by TGFBR3 R-HSA-9839373 4.331605e-01 0.363 0 0
Regulation of pyruvate metabolism R-HSA-9861718 4.331605e-01 0.363 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.390983e-01 0.357 0 0
Synthesis of PC R-HSA-1483191 4.390983e-01 0.357 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 4.431814e-01 0.353 0 0
Co-stimulation by CD28 R-HSA-389356 4.449743e-01 0.352 0 0
Gap junction trafficking and regulation R-HSA-157858 4.507891e-01 0.346 0 0
DNA Damage Bypass R-HSA-73893 4.507891e-01 0.346 0 0
Mitotic Anaphase R-HSA-68882 4.511296e-01 0.346 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 4.538533e-01 0.343 0 0
GPCR downstream signalling R-HSA-388396 4.564739e-01 0.341 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.565433e-01 0.341 0 0
Azathioprine ADME R-HSA-9748787 4.565433e-01 0.341 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 4.678726e-01 0.330 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 4.678726e-01 0.330 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.678726e-01 0.330 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.734489e-01 0.325 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.734489e-01 0.325 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.734489e-01 0.325 0 0
Smooth Muscle Contraction R-HSA-445355 4.734489e-01 0.325 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 4.778486e-01 0.321 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 4.789671e-01 0.320 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.789671e-01 0.320 0 0
Organelle biogenesis and maintenance R-HSA-1852241 4.793207e-01 0.319 0 0
SARS-CoV-2-host interactions R-HSA-9705683 4.834325e-01 0.316 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 4.844278e-01 0.315 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.844278e-01 0.315 0 0
Ribosome-associated quality control R-HSA-9948299 4.846247e-01 0.315 0 0
PTEN Regulation R-HSA-6807070 4.879925e-01 0.312 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 4.898316e-01 0.310 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.898316e-01 0.310 0 0
TNF signaling R-HSA-75893 4.898316e-01 0.310 0 0
Nuclear Envelope Breakdown R-HSA-2980766 4.951791e-01 0.305 0 0
Dual incision in TC-NER R-HSA-6782135 5.004709e-01 0.301 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 5.004709e-01 0.301 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 5.004709e-01 0.301 0 0
Clathrin-mediated endocytosis R-HSA-8856828 5.046250e-01 0.297 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.057075e-01 0.296 0 0
Triglyceride metabolism R-HSA-8979227 5.057075e-01 0.296 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 5.057075e-01 0.296 0 0
Amino acid transport across the plasma membrane R-HSA-352230 5.057075e-01 0.296 0 0
FCERI mediated NF-kB activation R-HSA-2871837 5.079097e-01 0.294 0 0
Signaling by Retinoic Acid R-HSA-5362517 5.108895e-01 0.292 0 0
Endogenous sterols R-HSA-211976 5.160176e-01 0.287 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.176789e-01 0.286 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 5.209068e-01 0.283 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 5.210922e-01 0.283 0 0
NCAM signaling for neurite out-growth R-HSA-375165 5.210922e-01 0.283 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 5.261139e-01 0.279 0 0
Potential therapeutics for SARS R-HSA-9679191 5.273195e-01 0.278 0 0
Xenobiotics R-HSA-211981 5.310832e-01 0.275 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 5.336743e-01 0.273 0 0
Interleukin-1 family signaling R-HSA-446652 5.336743e-01 0.273 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 5.399710e-01 0.268 0 0
HCMV Infection R-HSA-9609646 5.401894e-01 0.267 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 5.430975e-01 0.265 0 0
PPARA activates gene expression R-HSA-1989781 5.430975e-01 0.265 0 0
SARS-CoV-2 Infection R-HSA-9694516 5.432976e-01 0.265 0 0
Kidney development R-HSA-9830369 5.456826e-01 0.263 0 0
SLC-mediated transport of amino acids R-HSA-9958863 5.456826e-01 0.263 0 0
Viral Infection Pathways R-HSA-9824446 5.483430e-01 0.261 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 5.493063e-01 0.260 0 0
HCMV Late Events R-HSA-9610379 5.493063e-01 0.260 0 0
O-linked glycosylation of mucins R-HSA-913709 5.504479e-01 0.259 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 5.504479e-01 0.259 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 5.523886e-01 0.258 0 0
Cellular response to starvation R-HSA-9711097 5.523886e-01 0.258 0 0
Membrane Trafficking R-HSA-199991 5.566570e-01 0.254 0 0
Signaling by TGFB family members R-HSA-9006936 5.585089e-01 0.253 0 0
Regulation of TP53 Activity R-HSA-5633007 5.585089e-01 0.253 0 0
COPII-mediated vesicle transport R-HSA-204005 5.598300e-01 0.252 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 5.644478e-01 0.248 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 5.644478e-01 0.248 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 5.644478e-01 0.248 0 0
Selenoamino acid metabolism R-HSA-2408522 5.705713e-01 0.244 0 0
Switching of origins to a post-replicative state R-HSA-69052 5.735394e-01 0.241 0 0
Signaling by GPCR R-HSA-372790 5.766518e-01 0.239 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 5.798700e-01 0.237 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 5.824423e-01 0.235 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 5.824423e-01 0.235 0 0
Neuronal System R-HSA-112316 5.853431e-01 0.233 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 5.911060e-01 0.228 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 5.911605e-01 0.228 0 0
Integrin cell surface interactions R-HSA-216083 5.954514e-01 0.225 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 5.996976e-01 0.222 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 6.160262e-01 0.210 0 0
Influenza Infection R-HSA-168255 6.164289e-01 0.210 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.202731e-01 0.207 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 6.242603e-01 0.205 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 6.282058e-01 0.202 0 0
Bacterial Infection Pathways R-HSA-9824439 6.282973e-01 0.202 0 0
Pyruvate metabolism R-HSA-70268 6.359738e-01 0.197 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 6.405404e-01 0.193 0 0
Downstream TCR signaling R-HSA-202424 6.473242e-01 0.189 0 0
Toll-like Receptor Cascades R-HSA-168898 6.483101e-01 0.188 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 6.508705e-01 0.187 0 0
Mitochondrial protein degradation R-HSA-9837999 6.654649e-01 0.177 0 0
Collagen formation R-HSA-1474290 6.654649e-01 0.177 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 6.689802e-01 0.175 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 6.724587e-01 0.172 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 6.756687e-01 0.170 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.759009e-01 0.170 0 0
Potassium Channels R-HSA-1296071 6.759009e-01 0.170 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.793071e-01 0.168 0 0
Metabolism of RNA R-HSA-8953854 6.805742e-01 0.167 0 0
Post-translational protein phosphorylation R-HSA-8957275 6.826778e-01 0.166 0 0
Keratinization R-HSA-6805567 6.875251e-01 0.163 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 6.958118e-01 0.158 0 0
Translation R-HSA-72766 6.976886e-01 0.156 0 0
Muscle contraction R-HSA-397014 7.012836e-01 0.154 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 7.012836e-01 0.154 0 0
RSV-host interactions R-HSA-9833110 7.053064e-01 0.152 0 0
Nucleotide Excision Repair R-HSA-5696398 7.084053e-01 0.150 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 7.084053e-01 0.150 0 0
Platelet homeostasis R-HSA-418346 7.114718e-01 0.148 0 0
Synthesis of DNA R-HSA-69239 7.145063e-01 0.146 0 0
Stimuli-sensing channels R-HSA-2672351 7.175090e-01 0.144 0 0
Neddylation R-HSA-8951664 7.209807e-01 0.142 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.234206e-01 0.141 0 0
MyD88-independent TLR4 cascade R-HSA-166166 7.234206e-01 0.141 0 0
Inositol phosphate metabolism R-HSA-1483249 7.292092e-01 0.137 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 7.376671e-01 0.132 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 7.404276e-01 0.131 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 7.431592e-01 0.129 0 0
rRNA processing R-HSA-72312 7.435666e-01 0.129 0 0
L1CAM interactions R-HSA-373760 7.458623e-01 0.127 0 0
Rab regulation of trafficking R-HSA-9007101 7.485371e-01 0.126 0 0
Peptide hormone metabolism R-HSA-2980736 7.485371e-01 0.126 0 0
Cellular response to heat stress R-HSA-3371556 7.589592e-01 0.120 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 7.589592e-01 0.120 0 0
MHC class II antigen presentation R-HSA-2132295 7.640081e-01 0.117 0 0
Vesicle-mediated transport R-HSA-5653656 7.716901e-01 0.113 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 7.737926e-01 0.111 0 0
Cardiac conduction R-HSA-5576891 7.877182e-01 0.104 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 7.899549e-01 0.102 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.986651e-01 0.098 0 0
Interferon Signaling R-HSA-913531 7.986651e-01 0.098 0 0
Developmental Cell Lineages R-HSA-9734767 7.989896e-01 0.097 0 0
O-linked glycosylation R-HSA-5173105 8.028910e-01 0.095 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 8.028910e-01 0.095 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 8.318699e-01 0.080 0 0
Post-translational protein modification R-HSA-597592 8.518399e-01 0.070 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 8.581241e-01 0.066 0 0
SLC transporter disorders R-HSA-5619102 8.581241e-01 0.066 0 0
Metabolism of proteins R-HSA-392499 8.600047e-01 0.065 0 0
Leishmania parasite growth and survival R-HSA-9664433 8.682880e-01 0.061 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 8.682880e-01 0.061 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 8.710566e-01 0.060 0 0
Transmission across Chemical Synapses R-HSA-112315 8.770234e-01 0.057 0 0
Diseases of glycosylation R-HSA-3781865 8.828166e-01 0.054 0 0
Extracellular matrix organization R-HSA-1474244 8.850200e-01 0.053 0 0
Ion channel transport R-HSA-983712 8.888826e-01 0.051 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 9.011512e-01 0.045 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.042568e-01 0.044 0 0
Drug ADME R-HSA-9748784 9.192533e-01 0.037 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.353902e-01 0.029 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.407293e-01 0.027 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.481743e-01 0.023 0 0
Diseases of metabolism R-HSA-5668914 9.504256e-01 0.022 0 0
Cellular response to chemical stress R-HSA-9711123 9.526362e-01 0.021 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.574380e-01 0.019 0 0
Phospholipid metabolism R-HSA-1483257 9.645158e-01 0.016 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.656198e-01 0.015 0 0
Metabolism of steroids R-HSA-8957322 9.739927e-01 0.011 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.783291e-01 0.010 0 0
Biological oxidations R-HSA-211859 9.969963e-01 0.001 0 0
Transport of small molecules R-HSA-382551 9.985608e-01 0.001 0 0
Metabolism of lipids R-HSA-556833 9.999898e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
G2/M DNA damage checkpoint R-HSA-69473 2.331468e-15 14.632 0 0
Viral Infection Pathways R-HSA-9824446 1.287859e-14 13.890 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.487699e-14 13.827 0 0
Axon guidance R-HSA-422475 3.808065e-14 13.419 0 0
G2/M Checkpoints R-HSA-69481 5.628831e-14 13.250 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 7.327472e-14 13.135 0 0
M Phase R-HSA-68886 9.570122e-14 13.019 0 0
Packaging Of Telomere Ends R-HSA-171306 2.032818e-13 12.692 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 2.032818e-13 12.692 0 0
Nervous system development R-HSA-9675108 2.066125e-13 12.685 0 0
Cell Cycle R-HSA-1640170 2.297051e-13 12.639 0 0
DNA methylation R-HSA-5334118 3.809175e-13 12.419 0 0
HCMV Early Events R-HSA-9609690 5.963008e-13 12.225 0 0
Cell Cycle, Mitotic R-HSA-69278 5.857537e-13 12.232 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 6.685763e-13 12.175 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 8.075762e-13 12.093 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 8.075762e-13 12.093 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 9.148238e-13 12.039 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 1.205924e-12 11.919 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.748934e-12 11.757 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 2.051026e-12 11.688 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 1.876721e-12 11.727 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 2.051026e-12 11.688 0 0
PRC2 methylates histones and DNA R-HSA-212300 3.398171e-12 11.469 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 4.334533e-12 11.363 0 0
Cleavage of the damaged purine R-HSA-110331 4.334533e-12 11.363 0 0
Meiotic recombination R-HSA-912446 4.826251e-12 11.316 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 5.163092e-12 11.287 0 0
Depurination R-HSA-73927 5.497602e-12 11.260 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 5.577538e-12 11.254 0 0
Meiotic synapsis R-HSA-1221632 7.064460e-12 11.151 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 7.064460e-12 11.151 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 8.702816e-12 11.060 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 8.702816e-12 11.060 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.086697e-11 10.964 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 1.086697e-11 10.964 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.665512e-11 10.778 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.670597e-11 10.777 0 0
Depyrimidination R-HSA-73928 1.670597e-11 10.777 0 0
Defective pyroptosis R-HSA-9710421 2.057543e-11 10.687 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.433909e-11 10.614 0 0
Gap junction trafficking R-HSA-190828 2.523404e-11 10.598 0 0
Infectious disease R-HSA-5663205 2.687262e-11 10.571 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 3.082190e-11 10.511 0 0
Nucleosome assembly R-HSA-774815 3.082190e-11 10.511 0 0
Adherens junctions interactions R-HSA-418990 3.095124e-11 10.509 0 0
PKR-mediated signaling R-HSA-9833482 3.097378e-11 10.509 0 0
HCMV Infection R-HSA-9609646 3.379086e-11 10.471 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 3.381506e-11 10.471 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 3.381506e-11 10.471 0 0
Recycling pathway of L1 R-HSA-437239 4.545297e-11 10.342 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 5.489276e-11 10.260 0 0
Meiosis R-HSA-1500620 6.057943e-11 10.218 0 0
Gap junction trafficking and regulation R-HSA-157858 6.606082e-11 10.180 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.008187e-10 9.996 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 1.128775e-10 9.947 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.325167e-10 9.878 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.526488e-10 9.816 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.588552e-10 9.799 0 0
Cell junction organization R-HSA-446728 1.866722e-10 9.729 0 0
HDACs deacetylate histones R-HSA-3214815 1.876347e-10 9.727 0 0
Attenuation phase R-HSA-3371568 1.954621e-10 9.709 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.104132e-10 9.677 0 0
Cell-Cell communication R-HSA-1500931 2.283045e-10 9.641 0 0
Cell-cell junction organization R-HSA-421270 2.670422e-10 9.573 0 0
Transport of connexons to the plasma membrane R-HSA-190872 2.974710e-10 9.527 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 3.042107e-10 9.517 0 0
L1CAM interactions R-HSA-373760 3.154927e-10 9.501 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 3.555403e-10 9.449 0 0
Cell Cycle Checkpoints R-HSA-69620 4.057366e-10 9.392 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 4.145138e-10 9.382 0 0
Processing of DNA double-strand break ends R-HSA-5693607 5.036256e-10 9.298 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 5.066887e-10 9.295 0 0
Cellular response to heat stress R-HSA-3371556 5.102480e-10 9.292 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 5.704350e-10 9.244 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.285961e-10 9.138 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 9.925227e-10 9.003 0 0
DNA Double Strand Break Response R-HSA-5693606 1.139569e-09 8.943 0 0
Gene Silencing by RNA R-HSA-211000 1.165889e-09 8.933 0 0
Developmental Biology R-HSA-1266738 1.208218e-09 8.918 0 0
Diseases of programmed cell death R-HSA-9645723 1.311101e-09 8.882 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.420650e-09 8.848 0 0
G2/M Transition R-HSA-69275 1.648161e-09 8.783 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.705038e-09 8.768 0 0
HSF1-dependent transactivation R-HSA-3371571 1.695285e-09 8.771 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.888871e-09 8.724 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.705038e-09 8.768 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.942974e-09 8.712 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 2.334062e-09 8.632 0 0
Assembly of the pre-replicative complex R-HSA-68867 2.544686e-09 8.594 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 3.145415e-09 8.502 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 3.639321e-09 8.439 0 0
Aggrephagy R-HSA-9646399 3.970620e-09 8.401 0 0
Telomere Maintenance R-HSA-157579 4.285652e-09 8.368 0 0
RNA Polymerase I Transcription R-HSA-73864 4.625764e-09 8.335 0 0
Mitotic Prophase R-HSA-68875 4.730298e-09 8.325 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.844702e-09 8.233 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 5.844702e-09 8.233 0 0
HATs acetylate histones R-HSA-3214847 5.240612e-09 8.281 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 6.119357e-09 8.213 0 0
Amyloid fiber formation R-HSA-977225 6.555706e-09 8.183 0 0
Regulation of endogenous retroelements R-HSA-9842860 7.034258e-09 8.153 0 0
Reproduction R-HSA-1474165 1.286758e-08 7.891 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 1.750099e-08 7.757 0 0
Base Excision Repair R-HSA-73884 1.923466e-08 7.716 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 2.128015e-08 7.672 0 0
Estrogen-dependent gene expression R-HSA-9018519 2.212870e-08 7.655 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 2.296282e-08 7.639 0 0
Gap junction assembly R-HSA-190861 2.562638e-08 7.591 0 0
Co-inhibition by PD-1 R-HSA-389948 2.985991e-08 7.525 0 0
Translation initiation complex formation R-HSA-72649 4.169815e-08 7.380 0 0
HSF1 activation R-HSA-3371511 3.681592e-08 7.434 0 0
Disease R-HSA-1643685 3.660415e-08 7.436 0 0
Homology Directed Repair R-HSA-5693538 3.790393e-08 7.421 0 0
Chromosome Maintenance R-HSA-73886 4.824053e-08 7.317 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 5.445402e-08 7.264 0 0
MHC class II antigen presentation R-HSA-2132295 5.646687e-08 7.248 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 7.048959e-08 7.152 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 7.116949e-08 7.148 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 7.116949e-08 7.148 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 7.116949e-08 7.148 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 7.215214e-08 7.142 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 7.215214e-08 7.142 0 0
DNA Replication R-HSA-69306 7.915805e-08 7.102 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 8.458260e-08 7.073 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 9.355344e-08 7.029 0 0
Activation of HOX genes during differentiation R-HSA-5619507 9.355344e-08 7.029 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.773637e-08 7.010 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 9.896430e-08 7.005 0 0
Selective autophagy R-HSA-9663891 1.707063e-07 6.768 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.954085e-07 6.709 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 2.054722e-07 6.687 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 2.357458e-07 6.628 0 0
Signaling by NOTCH R-HSA-157118 2.651122e-07 6.577 0 0
Protein folding R-HSA-391251 2.691518e-07 6.570 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 2.756095e-07 6.560 0 0
Ub-specific processing proteases R-HSA-5689880 2.921745e-07 6.534 0 0
COPI-mediated anterograde transport R-HSA-6807878 4.142863e-07 6.383 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 4.512886e-07 6.346 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 4.725317e-07 6.326 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 4.779916e-07 6.321 0 0
TCF dependent signaling in response to WNT R-HSA-201681 5.139900e-07 6.289 0 0
Deubiquitination R-HSA-5688426 5.330382e-07 6.273 0 0
DNA Double-Strand Break Repair R-HSA-5693532 5.844029e-07 6.233 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 6.208295e-07 6.207 0 0
Autophagy R-HSA-9612973 6.997871e-07 6.155 0 0
Cilium Assembly R-HSA-5617833 7.487769e-07 6.126 0 0
Adaptive Immune System R-HSA-1280218 7.806710e-07 6.108 1 0
Transcriptional regulation by RUNX1 R-HSA-8878171 7.890219e-07 6.103 0 0
Regulation of CDH1 Function R-HSA-9764561 8.170728e-07 6.088 0 0
SARS-CoV-2-host interactions R-HSA-9705683 8.670567e-07 6.062 0 0
Mitotic Prometaphase R-HSA-68877 8.758225e-07 6.058 0 0
SARS-CoV-1-host interactions R-HSA-9692914 9.933996e-07 6.003 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.061893e-06 5.974 0 0
Kinesins R-HSA-983189 1.139868e-06 5.943 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.153208e-06 5.938 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.153208e-06 5.938 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.342398e-06 5.872 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.549043e-06 5.810 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 1.585038e-06 5.800 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 2.223014e-06 5.653 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.135255e-06 5.671 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.336119e-06 5.632 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.336119e-06 5.632 0 0
EPH-Ephrin signaling R-HSA-2682334 2.526541e-06 5.597 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.526541e-06 5.597 0 0
Cellular Senescence R-HSA-2559583 2.763337e-06 5.559 0 0
Mitotic Anaphase R-HSA-68882 2.810023e-06 5.551 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.940692e-06 5.532 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.250038e-06 5.488 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 3.413490e-06 5.467 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 4.258376e-06 5.371 0 0
Signal Transduction R-HSA-162582 4.775227e-06 5.321 0 0
Protein ubiquitination R-HSA-8852135 4.881997e-06 5.311 0 0
Organelle biogenesis and maintenance R-HSA-1852241 6.917704e-06 5.160 0 0
ESR-mediated signaling R-HSA-8939211 6.969566e-06 5.157 0 0
Immune System R-HSA-168256 7.016887e-06 5.154 1 0
Golgi-to-ER retrograde transport R-HSA-8856688 7.208750e-06 5.142 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 7.601891e-06 5.119 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 9.832715e-06 5.007 0 0
Macroautophagy R-HSA-1632852 1.261328e-05 4.899 0 0
Post NMDA receptor activation events R-HSA-438064 1.385158e-05 4.859 0 0
Signaling by WNT R-HSA-195721 1.445938e-05 4.840 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.673380e-05 4.776 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.673380e-05 4.776 0 0
Semaphorin interactions R-HSA-373755 1.673380e-05 4.776 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.791217e-05 4.747 0 0
ER to Golgi Anterograde Transport R-HSA-199977 1.821450e-05 4.740 0 0
Membrane Trafficking R-HSA-199991 1.860712e-05 4.730 0 0
AURKA Activation by TPX2 R-HSA-8854518 2.174665e-05 4.663 0 0
Formation of a pool of free 40S subunits R-HSA-72689 2.788177e-05 4.555 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 2.977830e-05 4.526 0 0
HCMV Late Events R-HSA-9610379 2.985411e-05 4.525 0 0
Chromatin modifying enzymes R-HSA-3247509 3.064641e-05 4.514 0 0
Hemostasis R-HSA-109582 3.161655e-05 4.500 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 3.838347e-05 4.416 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 3.900482e-05 4.409 0 0
Separation of Sister Chromatids R-HSA-2467813 4.136958e-05 4.383 0 0
Intraflagellar transport R-HSA-5620924 4.306522e-05 4.366 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 4.357149e-05 4.361 0 0
Centrosome maturation R-HSA-380287 4.469861e-05 4.350 0 0
Vesicle-mediated transport R-HSA-5653656 4.946655e-05 4.306 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 6.652771e-05 4.177 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 6.652771e-05 4.177 0 0
Interferon Signaling R-HSA-913531 4.995949e-05 4.301 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 6.652771e-05 4.177 0 0
Chromatin organization R-HSA-4839726 5.291642e-05 4.276 0 0
SARS-CoV-1 Infection R-HSA-9678108 6.996524e-05 4.155 0 0
SARS-CoV Infections R-HSA-9679506 8.042673e-05 4.095 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 8.458189e-05 4.073 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 1.027245e-04 3.988 0 0
Peptide chain elongation R-HSA-156902 1.170011e-04 3.932 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.311524e-04 3.882 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.325098e-04 3.878 0 0
Metabolism of proteins R-HSA-392499 1.373782e-04 3.862 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.380329e-04 3.860 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.447955e-04 3.839 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.811304e-04 3.742 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.811304e-04 3.742 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.858267e-04 3.731 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 1.997192e-04 3.700 0 0
MAP2K and MAPK activation R-HSA-5674135 2.372606e-04 3.625 0 0
Hedgehog 'off' state R-HSA-5610787 2.643537e-04 3.578 0 0
Formation of annular gap junctions R-HSA-196025 2.693899e-04 3.570 0 0
Signaling by Interleukins R-HSA-449147 3.250456e-04 3.488 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.264876e-04 3.486 0 0
Gap junction degradation R-HSA-190873 3.469186e-04 3.460 0 0
DNA Repair R-HSA-73894 3.495667e-04 3.456 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 3.689692e-04 3.433 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 3.689692e-04 3.433 0 0
Signaling downstream of RAS mutants R-HSA-9649948 3.689692e-04 3.433 0 0
Signaling by RAS mutants R-HSA-6802949 3.689692e-04 3.433 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.763219e-04 3.424 0 0
Interleukin-12 signaling R-HSA-9020591 3.806394e-04 3.419 0 0
Influenza Infection R-HSA-168255 4.021683e-04 3.396 0 0
Translation R-HSA-72766 5.315846e-04 3.274 0 0
Manipulation of host energy metabolism R-HSA-9636667 5.349475e-04 3.272 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 5.420439e-04 3.266 0 0
Smooth Muscle Contraction R-HSA-445355 6.379621e-04 3.195 0 0
Oncogenic MAPK signaling R-HSA-6802957 6.463056e-04 3.190 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 6.678989e-04 3.175 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 6.859120e-04 3.164 0 0
Activation of BH3-only proteins R-HSA-114452 7.412032e-04 3.130 0 0
Interleukin-12 family signaling R-HSA-447115 7.610516e-04 3.119 0 0
G0 and Early G1 R-HSA-1538133 9.045716e-04 3.044 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.378322e-04 3.028 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.865969e-04 3.006 0 0
Platelet degranulation R-HSA-114608 1.115850e-03 2.952 0 0
Generic Transcription Pathway R-HSA-212436 1.122652e-03 2.950 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.201434e-03 2.920 0 0
Eukaryotic Translation Termination R-HSA-72764 1.260344e-03 2.900 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.301245e-03 2.886 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.301245e-03 2.886 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.465929e-03 2.834 0 0
Selenocysteine synthesis R-HSA-2408557 1.661563e-03 2.779 0 0
Platelet activation, signaling and aggregation R-HSA-76002 1.747623e-03 2.758 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 1.764530e-03 2.753 0 0
Viral mRNA Translation R-HSA-192823 1.814798e-03 2.741 0 0
Ribosome-associated quality control R-HSA-9948299 1.829543e-03 2.738 0 0
Signaling by Hedgehog R-HSA-5358351 1.829543e-03 2.738 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 2.035795e-03 2.691 0 0
RNA Polymerase II Transcription R-HSA-73857 2.234701e-03 2.651 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 2.244763e-03 2.649 0 0
Signaling by RAF1 mutants R-HSA-9656223 2.277095e-03 2.643 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.447843e-03 2.611 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 2.747431e-03 2.561 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.815362e-03 2.550 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 2.747431e-03 2.561 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 3.330133e-03 2.478 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.717336e-03 2.566 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 3.350453e-03 2.475 0 0
Cellular response to starvation R-HSA-9711097 3.677179e-03 2.434 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 3.046375e-03 2.516 0 0
Gene expression (Transcription) R-HSA-74160 3.615684e-03 2.442 0 0
Signaling by ROBO receptors R-HSA-376176 3.525588e-03 2.453 0 0
Syndecan interactions R-HSA-3000170 4.268994e-03 2.370 0 0
Selenoamino acid metabolism R-HSA-2408522 4.402837e-03 2.356 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 4.574832e-03 2.340 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 4.609629e-03 2.336 0 0
Signaling by VEGF R-HSA-194138 4.930799e-03 2.307 0 0
CHL1 interactions R-HSA-447041 5.649925e-03 2.248 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 5.649925e-03 2.248 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 5.835196e-03 2.234 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 6.008332e-03 2.221 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 6.091700e-03 2.215 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 8.019310e-03 2.096 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 8.234712e-03 2.084 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 9.343968e-03 2.029 0 0
Post-translational protein modification R-HSA-597592 1.052686e-02 1.978 0 0
PECAM1 interactions R-HSA-210990 1.075904e-02 1.968 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.099331e-02 1.959 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.099331e-02 1.959 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.099331e-02 1.959 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.099331e-02 1.959 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.099331e-02 1.959 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.099331e-02 1.959 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.127079e-02 1.948 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.226241e-02 1.911 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 1.244220e-02 1.905 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.244757e-02 1.905 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.244757e-02 1.905 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.244757e-02 1.905 0 0
Programmed Cell Death R-HSA-5357801 1.316357e-02 1.881 0 0
Signaling by NOTCH4 R-HSA-9013694 1.351073e-02 1.869 0 0
Scavenging by Class F Receptors R-HSA-3000484 1.385197e-02 1.858 0 0
Transmission across Chemical Synapses R-HSA-112315 1.471443e-02 1.832 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 1.487274e-02 1.828 0 0
Muscle contraction R-HSA-397014 1.531418e-02 1.815 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.663162e-02 1.779 0 0
Extracellular matrix organization R-HSA-1474244 1.682197e-02 1.774 0 0
Protein methylation R-HSA-8876725 1.911751e-02 1.719 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.930015e-02 1.714 0 0
Signaling by SCF-KIT R-HSA-1433557 1.947943e-02 1.710 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 2.103168e-02 1.677 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 2.103168e-02 1.677 0 0
MAPK family signaling cascades R-HSA-5683057 2.168867e-02 1.664 0 0
Gluconeogenesis R-HSA-70263 2.478716e-02 1.606 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.508692e-02 1.601 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 2.515229e-02 1.599 0 0
Asparagine N-linked glycosylation R-HSA-446203 2.635752e-02 1.579 0 0
Ephrin signaling R-HSA-3928664 2.722425e-02 1.565 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.722425e-02 1.565 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.841626e-02 1.546 0 0
Metabolism of RNA R-HSA-8953854 2.865712e-02 1.543 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.943228e-02 1.531 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 2.953857e-02 1.530 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.077059e-02 1.512 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 3.079630e-02 1.512 0 0
Signal transduction by L1 R-HSA-445144 3.170921e-02 1.499 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 3.262070e-02 1.487 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 3.340756e-02 1.476 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.405327e-02 1.468 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.416970e-02 1.466 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 3.646275e-02 1.438 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.646275e-02 1.438 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 3.652068e-02 1.437 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 3.893592e-02 1.410 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.893592e-02 1.410 0 0
Potential therapeutics for SARS R-HSA-9679191 3.980701e-02 1.400 0 0
RSV-host interactions R-HSA-9833110 4.073896e-02 1.390 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 4.147112e-02 1.382 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.325737e-02 1.364 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.325737e-02 1.364 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.325737e-02 1.364 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.325737e-02 1.364 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.325737e-02 1.364 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.325737e-02 1.364 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.325737e-02 1.364 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 4.325737e-02 1.364 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.325737e-02 1.364 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.325737e-02 1.364 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.325737e-02 1.364 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.325737e-02 1.364 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 4.325737e-02 1.364 0 0
Mitochondrial protein import R-HSA-1268020 4.335629e-02 1.363 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 4.335629e-02 1.363 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 4.513527e-02 1.345 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 4.599108e-02 1.337 0 0
Neuronal System R-HSA-112316 4.632990e-02 1.334 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 6.418307e-02 1.193 0 0
IRS activation R-HSA-74713 7.447461e-02 1.128 0 0
G2 Phase R-HSA-68911 7.447461e-02 1.128 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 8.465360e-02 1.072 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 8.465360e-02 1.072 0 0
G2/M DNA replication checkpoint R-HSA-69478 9.472126e-02 1.024 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 9.472126e-02 1.024 0 0
Cristae formation R-HSA-8949613 5.219970e-02 1.282 0 0
Striated Muscle Contraction R-HSA-390522 7.300114e-02 1.137 0 0
mRNA Splicing - Major Pathway R-HSA-72163 8.891038e-02 1.051 0 0
Integrin signaling R-HSA-354192 6.988624e-02 1.156 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 6.988624e-02 1.156 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 8.260489e-02 1.083 0 0
PTEN Regulation R-HSA-6807070 9.592437e-02 1.018 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 8.465360e-02 1.072 0 0
Leishmania phagocytosis R-HSA-9664417 9.760976e-02 1.011 0 0
Parasite infection R-HSA-9664407 9.760976e-02 1.011 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.760976e-02 1.011 0 0
PIP3 activates AKT signaling R-HSA-1257604 6.201458e-02 1.208 0 0
MET interacts with TNS proteins R-HSA-8875513 5.377774e-02 1.269 0 0
Phosphorylation of Emi1 R-HSA-176417 8.465360e-02 1.072 0 0
Interaction between L1 and Ankyrins R-HSA-445095 5.219970e-02 1.282 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 7.936179e-02 1.100 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.808345e-02 1.236 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.808345e-02 1.236 0 0
G1/S Transition R-HSA-69206 7.091502e-02 1.149 0 0
GPVI-mediated activation cascade R-HSA-114604 8.260489e-02 1.083 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.596611e-02 1.018 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 7.832586e-02 1.106 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 7.447461e-02 1.128 0 0
Co-inhibition by BTLA R-HSA-9927353 7.447461e-02 1.128 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 9.472126e-02 1.024 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 8.465360e-02 1.072 0 0
Nef and signal transduction R-HSA-164944 9.472126e-02 1.024 0 0
Molecules associated with elastic fibres R-HSA-2129379 6.379405e-02 1.195 0 0
Elastic fibre formation R-HSA-1566948 8.921023e-02 1.050 0 0
Sensory processing of sound R-HSA-9659379 7.289213e-02 1.137 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 8.920301e-02 1.050 0 0
RAF/MAP kinase cascade R-HSA-5673001 5.716776e-02 1.243 0 0
Regulation of necroptotic cell death R-HSA-5675482 6.988624e-02 1.156 0 0
Ovarian tumor domain proteases R-HSA-5689896 8.588812e-02 1.066 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 5.294063e-02 1.276 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.921023e-02 1.050 0 0
rRNA processing R-HSA-72312 6.235275e-02 1.205 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 8.499109e-02 1.071 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 7.616010e-02 1.118 0 0
Interleukin-37 signaling R-HSA-9008059 6.081956e-02 1.216 0 0
G1/S-Specific Transcription R-HSA-69205 8.260489e-02 1.083 0 0
Regulation of TP53 Degradation R-HSA-6804757 8.260489e-02 1.083 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 9.256996e-02 1.034 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 5.808345e-02 1.236 0 0
Apoptosis R-HSA-109581 5.071892e-02 1.295 0 0
Downstream TCR signaling R-HSA-202424 9.788317e-02 1.009 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.939747e-02 1.003 0 0
mRNA Splicing R-HSA-72172 1.042364e-01 0.982 0 0
Regulation of PTEN localization R-HSA-8948747 1.046788e-01 0.980 0 0
Recycling of eIF2:GDP R-HSA-72731 1.046788e-01 0.980 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 1.046788e-01 0.980 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.046788e-01 0.980 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.063612e-01 0.973 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.084514e-01 0.965 0 0
Mitochondrial protein degradation R-HSA-9837999 1.091925e-01 0.962 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.098912e-01 0.959 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 1.098912e-01 0.959 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 1.134519e-01 0.945 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.134519e-01 0.945 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.170422e-01 0.932 0 0
Protein localization R-HSA-9609507 1.226169e-01 0.911 0 0
FOXO-mediated transcription R-HSA-9614085 1.233930e-01 0.909 0 0
Lipophagy R-HSA-9613354 1.242683e-01 0.906 0 0
ALK mutants bind TKIs R-HSA-9700645 1.242683e-01 0.906 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.242683e-01 0.906 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 1.242683e-01 0.906 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 1.242683e-01 0.906 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.242683e-01 0.906 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.242683e-01 0.906 0 0
Glycolysis R-HSA-70171 1.258227e-01 0.900 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.279797e-01 0.893 0 0
Degradation of CDH1 R-HSA-9766229 1.316777e-01 0.880 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.316777e-01 0.880 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.316777e-01 0.880 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.339027e-01 0.873 0 0
Regulation of CDH11 function R-HSA-9762292 1.339027e-01 0.873 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 1.339027e-01 0.873 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.339027e-01 0.873 0 0
MAPK3 (ERK1) activation R-HSA-110056 1.339027e-01 0.873 0 0
Signal attenuation R-HSA-74749 1.339027e-01 0.873 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.357113e-01 0.867 0 0
Regulation of TP53 Activity R-HSA-5633007 1.360521e-01 0.866 0 0
HIV Infection R-HSA-162906 1.401446e-01 0.853 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.429141e-01 0.845 0 0
Orc1 removal from chromatin R-HSA-68949 1.429141e-01 0.845 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 1.429141e-01 0.845 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.434316e-01 0.843 0 0
vRNP Assembly R-HSA-192905 1.434316e-01 0.843 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.458582e-01 0.836 0 0
Signaling by ALK in cancer R-HSA-9700206 1.458582e-01 0.836 0 0
Regulation of PTEN stability and activity R-HSA-8948751 1.467039e-01 0.834 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 1.467039e-01 0.834 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 1.505143e-01 0.822 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.528563e-01 0.816 0 0
TCR signaling R-HSA-202403 1.536273e-01 0.814 1 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 1.543444e-01 0.812 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 1.581933e-01 0.801 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.581933e-01 0.801 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.620602e-01 0.790 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.620602e-01 0.790 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 1.621778e-01 0.790 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 1.621778e-01 0.790 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.621778e-01 0.790 0 0
VLDLR internalisation and degradation R-HSA-8866427 1.621778e-01 0.790 0 0
Regulation of IFNG signaling R-HSA-877312 1.621778e-01 0.790 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.621778e-01 0.790 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 1.621778e-01 0.790 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.641838e-01 0.785 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.713974e-01 0.766 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.713974e-01 0.766 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.713974e-01 0.766 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.713974e-01 0.766 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 1.713974e-01 0.766 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.713974e-01 0.766 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.737600e-01 0.760 0 0
Glucose metabolism R-HSA-70326 1.776725e-01 0.750 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.804066e-01 0.744 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.805160e-01 0.743 0 0
CRMPs in Sema3A signaling R-HSA-399956 1.805160e-01 0.743 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.805160e-01 0.743 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.805160e-01 0.743 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 1.805160e-01 0.743 0 0
Regulation of KIT signaling R-HSA-1433559 1.805160e-01 0.743 0 0
Signal regulatory protein family interactions R-HSA-391160 1.805160e-01 0.743 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 1.855917e-01 0.731 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.886768e-01 0.724 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.895349e-01 0.722 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.895349e-01 0.722 0 0
Erythropoietin activates RAS R-HSA-9027284 1.895349e-01 0.722 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.895349e-01 0.722 0 0
Other semaphorin interactions R-HSA-416700 1.895349e-01 0.722 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.942441e-01 0.712 0 0
Host Interactions of HIV factors R-HSA-162909 1.970432e-01 0.705 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 1.984550e-01 0.702 0 0
Phosphorylation of the APC/C R-HSA-176412 1.984550e-01 0.702 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 1.984550e-01 0.702 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.984550e-01 0.702 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 1.984550e-01 0.702 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 1.984550e-01 0.702 0 0
Developmental Cell Lineages R-HSA-9734767 2.053638e-01 0.687 0 0
Regulated Necrosis R-HSA-5218859 2.055478e-01 0.687 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 2.072776e-01 0.683 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 2.072776e-01 0.683 0 0
Fibronectin matrix formation R-HSA-1566977 2.072776e-01 0.683 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.072776e-01 0.683 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 2.135964e-01 0.670 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.160035e-01 0.666 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.160035e-01 0.666 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 2.160035e-01 0.666 0 0
Uptake and function of anthrax toxins R-HSA-5210891 2.160035e-01 0.666 0 0
ECM proteoglycans R-HSA-3000178 2.176321e-01 0.662 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 2.216746e-01 0.654 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.246340e-01 0.649 0 0
Platelet sensitization by LDL R-HSA-432142 2.246340e-01 0.649 0 0
Switching of origins to a post-replicative state R-HSA-69052 2.257232e-01 0.646 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.331699e-01 0.632 0 0
Rap1 signalling R-HSA-392517 2.331699e-01 0.632 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.331699e-01 0.632 0 0
The NLRP3 inflammasome R-HSA-844456 2.331699e-01 0.632 0 0
Regulation of signaling by CBL R-HSA-912631 2.331699e-01 0.632 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.371396e-01 0.625 0 0
UCH proteinases R-HSA-5689603 2.378997e-01 0.624 0 0
Leishmania infection R-HSA-9658195 2.412071e-01 0.618 0 0
Parasitic Infection Pathways R-HSA-9824443 2.412071e-01 0.618 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 2.416125e-01 0.617 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.416125e-01 0.617 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.416125e-01 0.617 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.416125e-01 0.617 0 0
Nuclear Receptor transcription pathway R-HSA-383280 2.460370e-01 0.609 0 0
Integrin cell surface interactions R-HSA-216083 2.460370e-01 0.609 0 0
PCP/CE pathway R-HSA-4086400 2.460370e-01 0.609 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.488722e-01 0.604 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.499625e-01 0.602 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.499625e-01 0.602 0 0
Basigin interactions R-HSA-210991 2.499625e-01 0.602 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.582212e-01 0.588 0 0
Attachment and Entry R-HSA-9694614 2.582212e-01 0.588 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.582212e-01 0.588 0 0
Late Phase of HIV Life Cycle R-HSA-162599 2.606784e-01 0.584 0 0
FGFR2 alternative splicing R-HSA-6803529 2.663894e-01 0.574 0 0
LDL clearance R-HSA-8964038 2.663894e-01 0.574 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 2.663894e-01 0.574 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 2.744682e-01 0.562 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.744682e-01 0.562 0 0
Formation of the ureteric bud R-HSA-9830674 2.744682e-01 0.562 0 0
Growth hormone receptor signaling R-HSA-982772 2.744682e-01 0.562 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 2.744682e-01 0.562 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 2.786484e-01 0.555 0 0
Neutrophil degranulation R-HSA-6798695 2.786901e-01 0.555 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.824585e-01 0.549 0 0
Neurodegenerative Diseases R-HSA-8863678 2.824585e-01 0.549 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.824585e-01 0.549 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.824585e-01 0.549 0 0
Complex III assembly R-HSA-9865881 2.824585e-01 0.549 0 0
XBP1(S) activates chaperone genes R-HSA-381038 2.827234e-01 0.549 0 0
MITF-M-dependent gene expression R-HSA-9856651 2.844932e-01 0.546 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.874847e-01 0.541 0 0
Laminin interactions R-HSA-3000157 2.903613e-01 0.537 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 2.903613e-01 0.537 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 2.903613e-01 0.537 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 2.903613e-01 0.537 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.903613e-01 0.537 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 2.903613e-01 0.537 0 0
Interleukin-1 family signaling R-HSA-446652 2.904788e-01 0.537 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.981776e-01 0.526 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 2.981776e-01 0.526 0 0
MET activates PTK2 signaling R-HSA-8874081 2.981776e-01 0.526 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 2.981776e-01 0.526 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 3.030609e-01 0.518 0 0
Bacterial Infection Pathways R-HSA-9824439 3.034236e-01 0.518 0 0
HIV Life Cycle R-HSA-162587 3.054801e-01 0.515 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 3.059082e-01 0.514 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 3.059082e-01 0.514 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 3.059082e-01 0.514 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 3.059082e-01 0.514 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.059082e-01 0.514 0 0
IRE1alpha activates chaperones R-HSA-381070 3.071179e-01 0.513 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 3.084852e-01 0.511 0 0
HIV elongation arrest and recovery R-HSA-167287 3.135541e-01 0.504 0 0
Pausing and recovery of HIV elongation R-HSA-167290 3.135541e-01 0.504 0 0
Insulin receptor recycling R-HSA-77387 3.135541e-01 0.504 0 0
Telomere Extension By Telomerase R-HSA-171319 3.135541e-01 0.504 0 0
Inflammasomes R-HSA-622312 3.135541e-01 0.504 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 3.152182e-01 0.501 0 0
Cell surface interactions at the vascular wall R-HSA-202733 3.168686e-01 0.499 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 3.192607e-01 0.496 0 0
Late endosomal microautophagy R-HSA-9615710 3.211163e-01 0.493 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.211163e-01 0.493 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.211163e-01 0.493 0 0
Signaling by Erythropoietin R-HSA-9006335 3.211163e-01 0.493 0 0
DARPP-32 events R-HSA-180024 3.211163e-01 0.493 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 3.232977e-01 0.490 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 3.273286e-01 0.485 0 0
Activation of the pre-replicative complex R-HSA-68962 3.285957e-01 0.483 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.285957e-01 0.483 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 3.285957e-01 0.483 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 3.285957e-01 0.483 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.285957e-01 0.483 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 3.285957e-01 0.483 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.353712e-01 0.474 0 0
Downstream signal transduction R-HSA-186763 3.359931e-01 0.474 0 0
Budding and maturation of HIV virion R-HSA-162588 3.359931e-01 0.474 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 3.359931e-01 0.474 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 3.359931e-01 0.474 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.359931e-01 0.474 0 0
Post-translational protein phosphorylation R-HSA-8957275 3.393822e-01 0.469 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 3.433094e-01 0.464 0 0
Diseases of mitotic cell cycle R-HSA-9675126 3.433094e-01 0.464 0 0
HS-GAG degradation R-HSA-2024096 3.433094e-01 0.464 0 0
ABC-family proteins mediated transport R-HSA-382556 3.473818e-01 0.459 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.505456e-01 0.455 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.505456e-01 0.455 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.505456e-01 0.455 0 0
PI Metabolism R-HSA-1483255 3.553496e-01 0.449 0 0
Vpu mediated degradation of CD4 R-HSA-180534 3.577025e-01 0.446 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.577025e-01 0.446 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 3.647810e-01 0.438 0 0
Nuclear import of Rev protein R-HSA-180746 3.647810e-01 0.438 0 0
eNOS activation R-HSA-203615 3.647810e-01 0.438 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 3.647810e-01 0.438 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 3.647810e-01 0.438 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.717819e-01 0.430 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 3.717819e-01 0.430 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 3.717819e-01 0.430 0 0
Regulation of Apoptosis R-HSA-169911 3.717819e-01 0.430 0 0
PERK regulates gene expression R-HSA-381042 3.717819e-01 0.430 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 3.717819e-01 0.430 0 0
HS-GAG biosynthesis R-HSA-2022928 3.787060e-01 0.422 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 3.787060e-01 0.422 0 0
Synthesis of DNA R-HSA-69239 3.790380e-01 0.421 0 0
Degradation of DVL R-HSA-4641258 3.855543e-01 0.414 0 0
Degradation of AXIN R-HSA-4641257 3.855543e-01 0.414 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 3.855543e-01 0.414 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.855543e-01 0.414 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.923275e-01 0.406 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 3.923275e-01 0.406 0 0
MET promotes cell motility R-HSA-8875878 3.923275e-01 0.406 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.990264e-01 0.399 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.990264e-01 0.399 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.990264e-01 0.399 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 3.990264e-01 0.399 0 0
Plasma lipoprotein clearance R-HSA-8964043 3.990264e-01 0.399 0 0
Stabilization of p53 R-HSA-69541 3.990264e-01 0.399 0 0
Pentose phosphate pathway R-HSA-71336 3.990264e-01 0.399 0 0
Signaling by ALK R-HSA-201556 3.990264e-01 0.399 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 4.056519e-01 0.392 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 4.056519e-01 0.392 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 4.056519e-01 0.392 0 0
HIV Transcription Elongation R-HSA-167169 4.056519e-01 0.392 0 0
Generation of second messenger molecules R-HSA-202433 4.056519e-01 0.392 1 1
Regulation of RUNX3 expression and activity R-HSA-8941858 4.056519e-01 0.392 0 0
Interleukin-2 family signaling R-HSA-451927 4.056519e-01 0.392 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 4.100424e-01 0.387 0 0
Metabolism of amino acids and derivatives R-HSA-71291 4.109057e-01 0.386 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 4.122048e-01 0.385 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 4.122048e-01 0.385 0 0
Interferon alpha/beta signaling R-HSA-909733 4.176775e-01 0.379 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 4.176775e-01 0.379 1 1
Degradation of CRY and PER proteins R-HSA-9932298 4.186858e-01 0.378 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 4.186858e-01 0.378 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 4.186858e-01 0.378 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 4.186858e-01 0.378 0 0
Negative regulation of MAPK pathway R-HSA-5675221 4.186858e-01 0.378 0 0
Mitochondrial biogenesis R-HSA-1592230 4.252629e-01 0.371 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 4.314355e-01 0.365 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 4.327970e-01 0.364 0 0
Proteasome assembly R-HSA-9907900 4.377056e-01 0.359 0 0
Methylation R-HSA-156581 4.377056e-01 0.359 0 0
Cyclin D associated events in G1 R-HSA-69231 4.377056e-01 0.359 0 0
G1 Phase R-HSA-69236 4.377056e-01 0.359 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 4.402787e-01 0.356 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 4.439070e-01 0.353 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 4.439070e-01 0.353 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.439070e-01 0.353 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 4.439070e-01 0.353 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 4.439070e-01 0.353 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 4.439070e-01 0.353 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 4.439070e-01 0.353 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 4.439070e-01 0.353 0 0
Somitogenesis R-HSA-9824272 4.439070e-01 0.353 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 4.451363e-01 0.352 1 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.500404e-01 0.347 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.500404e-01 0.347 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 4.500404e-01 0.347 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 4.500404e-01 0.347 0 0
Regulation of pyruvate metabolism R-HSA-9861718 4.500404e-01 0.347 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.561065e-01 0.341 0 0
Co-stimulation by CD28 R-HSA-389356 4.621061e-01 0.335 0 0
GPER1 signaling R-HSA-9634597 4.621061e-01 0.335 0 0
NGF-stimulated transcription R-HSA-9031628 4.621061e-01 0.335 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 4.696543e-01 0.328 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.739085e-01 0.324 0 0
Azathioprine ADME R-HSA-9748787 4.739085e-01 0.324 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 4.797128e-01 0.319 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 4.797128e-01 0.319 0 0
Hedgehog ligand biogenesis R-HSA-5358346 4.797128e-01 0.319 0 0
mRNA 3'-end processing R-HSA-72187 4.854534e-01 0.314 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.854534e-01 0.314 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 4.854534e-01 0.314 0 0
Neurexins and neuroligins R-HSA-6794361 4.854534e-01 0.314 0 0
Circadian clock R-HSA-9909396 4.875446e-01 0.312 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.911310e-01 0.309 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.911310e-01 0.309 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.050568e-01 0.297 0 0
NRAGE signals death through JNK R-HSA-193648 5.077927e-01 0.294 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 5.185980e-01 0.285 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 5.239119e-01 0.281 0 0
Extension of Telomeres R-HSA-180786 5.239119e-01 0.281 0 0
Signaling by ERBB2 R-HSA-1227986 5.291674e-01 0.276 0 0
Metabolism of polyamines R-HSA-351202 5.291674e-01 0.276 0 0
Innate Immune System R-HSA-168249 5.305885e-01 0.275 1 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.343653e-01 0.272 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 5.343653e-01 0.272 0 0
Formation of paraxial mesoderm R-HSA-9793380 5.343653e-01 0.272 0 0
Signaling by PDGF R-HSA-186797 5.395060e-01 0.268 0 0
tRNA processing in the nucleus R-HSA-6784531 5.395060e-01 0.268 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.395060e-01 0.268 0 0
Complex I biogenesis R-HSA-6799198 5.445904e-01 0.264 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 5.445904e-01 0.264 0 0
Signaling by PTK6 R-HSA-8848021 5.445904e-01 0.264 0 0
S Phase R-HSA-69242 5.487446e-01 0.261 0 0
Signaling by NTRKs R-HSA-166520 5.487446e-01 0.261 0 0
Insulin receptor signalling cascade R-HSA-74751 5.496189e-01 0.260 0 0
CD22 mediated BCR regulation R-HSA-5690714 5.496189e-01 0.260 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.496189e-01 0.260 0 0
Cellular response to hypoxia R-HSA-1234174 5.545922e-01 0.256 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 5.552233e-01 0.256 0 0
Kidney development R-HSA-9830369 5.643755e-01 0.248 0 0
Transcription of the HIV genome R-HSA-167172 5.691868e-01 0.245 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.786513e-01 0.238 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 5.786513e-01 0.238 0 0
Retinoid metabolism and transport R-HSA-975634 5.833057e-01 0.234 0 0
Metabolism of cofactors R-HSA-8978934 5.833057e-01 0.234 0 0
Hedgehog 'on' state R-HSA-5632684 5.833057e-01 0.234 0 0
Signaling by TGFB family members R-HSA-9006936 5.866281e-01 0.232 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 5.879091e-01 0.231 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 5.924618e-01 0.227 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 5.924618e-01 0.227 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 5.969645e-01 0.224 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 6.072955e-01 0.217 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 6.144860e-01 0.211 0 0
G alpha (12/13) signalling events R-HSA-416482 6.144860e-01 0.211 0 0
ABC transporter disorders R-HSA-5619084 6.144860e-01 0.211 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 6.187467e-01 0.208 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 6.187467e-01 0.208 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 6.187467e-01 0.208 0 0
Cellular response to chemical stress R-HSA-9711123 6.188867e-01 0.208 0 0
Signaling by FGFR2 R-HSA-5654738 6.229606e-01 0.206 0 0
Signaling by MET R-HSA-6806834 6.229606e-01 0.206 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 6.229606e-01 0.206 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 6.271282e-01 0.203 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 6.312499e-01 0.200 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 6.353264e-01 0.197 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.393580e-01 0.194 0 0
Protein-protein interactions at synapses R-HSA-6794362 6.433453e-01 0.192 0 0
Amplification of signal from the kinetochores R-HSA-141424 6.472888e-01 0.189 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 6.472888e-01 0.189 0 0
Sulfur amino acid metabolism R-HSA-1614635 6.511889e-01 0.186 0 0
Pyruvate metabolism R-HSA-70268 6.550461e-01 0.184 0 0
ER-Phagosome pathway R-HSA-1236974 6.626338e-01 0.179 0 0
Neurotransmitter release cycle R-HSA-112310 6.663651e-01 0.176 0 0
Signaling by Insulin receptor R-HSA-74752 6.773147e-01 0.169 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 6.773147e-01 0.169 0 0
FCGR activation R-HSA-2029481 6.808846e-01 0.167 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 6.879069e-01 0.162 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 6.947756e-01 0.158 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 6.981533e-01 0.156 0 0
Signaling by FGFR R-HSA-190236 7.014939e-01 0.154 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 7.047977e-01 0.152 0 0
Mitotic Spindle Checkpoint R-HSA-69618 7.080652e-01 0.150 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 7.112967e-01 0.148 0 0
Interleukin-1 signaling R-HSA-9020702 7.112967e-01 0.148 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.207792e-01 0.142 0 0
Opioid Signalling R-HSA-111885 7.207792e-01 0.142 0 0
Nucleotide Excision Repair R-HSA-5696398 7.269282e-01 0.139 0 0
Platelet homeostasis R-HSA-418346 7.299520e-01 0.137 0 0
Antigen processing-Cross presentation R-HSA-1236975 7.359001e-01 0.133 0 0
Stimuli-sensing channels R-HSA-2672351 7.359001e-01 0.133 0 0
FCERI mediated MAPK activation R-HSA-2871796 7.474083e-01 0.126 0 0
Inositol phosphate metabolism R-HSA-1483249 7.474083e-01 0.126 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 7.610946e-01 0.119 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 7.630857e-01 0.117 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 7.638080e-01 0.117 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 7.910072e-01 0.102 0 0
FCERI mediated NF-kB activation R-HSA-2871837 8.346665e-01 0.078 0 0
Visual phototransduction R-HSA-2187338 8.401137e-01 0.076 0 0
Gastrulation R-HSA-9758941 8.436456e-01 0.074 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.487986e-01 0.071 0 0
Death Receptor Signaling R-HSA-73887 8.521397e-01 0.069 0 0
Interferon gamma signaling R-HSA-877300 8.601748e-01 0.065 0 0
Phospholipid metabolism R-HSA-1483257 8.648034e-01 0.063 0 0
tRNA processing R-HSA-72306 8.777312e-01 0.057 0 0
G alpha (s) signalling events R-HSA-418555 8.790912e-01 0.056 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 8.790912e-01 0.056 0 0
Leishmania parasite growth and survival R-HSA-9664433 8.817662e-01 0.055 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 8.817662e-01 0.055 0 0
Respiratory electron transport R-HSA-611105 8.881992e-01 0.051 0 0
Diseases of glycosylation R-HSA-3781865 8.954608e-01 0.048 0 0
Ion channel transport R-HSA-983712 9.011525e-01 0.045 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.054831e-01 0.043 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.271471e-01 0.033 0 0
Drug ADME R-HSA-9748784 9.293805e-01 0.032 0 0
Neddylation R-HSA-8951664 9.317182e-01 0.031 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.442132e-01 0.025 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.490096e-01 0.023 0 0
Diseases of metabolism R-HSA-5668914 9.598460e-01 0.018 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.640241e-01 0.016 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.656090e-01 0.015 0 0
Metabolism of steroids R-HSA-8957322 9.785863e-01 0.009 0 0
Biological oxidations R-HSA-211859 9.840750e-01 0.007 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.891406e-01 0.005 0 0
G alpha (i) signalling events R-HSA-418594 9.917294e-01 0.004 0 0
Fatty acid metabolism R-HSA-8978868 9.917294e-01 0.004 0 0
GPCR downstream signalling R-HSA-388396 9.935710e-01 0.003 0 0
Transport of small molecules R-HSA-382551 9.961951e-01 0.002 0 0
Signaling by GPCR R-HSA-372790 9.970514e-01 0.001 0 0
Sensory Perception R-HSA-9709957 9.996438e-01 0.000 0 0
Metabolism R-HSA-1430728 9.999302e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 9.999701e-01 0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways