IKKE
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | T949 | Sugiyama | POTEF A26C1B | TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| A6NMY6 | S127 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | AQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEINRVy |
| O00273 | S305 | Sugiyama | DFFA DFF1 DFF45 H13 | VQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDLQNPKR |
| O00410 | S239 | Sugiyama | IPO5 KPNB3 RANBP5 | PGFLQAVNDSCYQNDDSVLKsLVEIADTVPKYLRPHLEATL |
| O00429 | T586 | Sugiyama | DNM1L DLP1 DRP1 | ETKNVAsGGGGVGDGVQEPTtGNWRGMLKtSKAEELLAEEK |
| O00571 | S102 | EPSD|PSP | DDX3X DBX DDX3 | ssFFsDRGsGsRGRFDDRGRsDyDGIGsRGDRSGFGKFERG |
| O00625 | S225 | Sugiyama | PIR | PDDAQQKIEPHHTAVLGEGDsVQVENKDPKRSHFVLIAGEP |
| O14519 | S46 | SIGNOR|EPSD|PSP | CDK2AP1 CDKAP1 DOC1 | stsMATSSQYRQLLSDYGPPsLGYTQGTGNSQVPQSKYAEL |
| O14545 | S320 | Sugiyama | TRAFD1 FLN29 | YPEELLIDHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQN |
| O14893 | S131 | Sugiyama | GEMIN2 SIP1 | STVRQNVNKHRSHWKsQQLDsNVTMPKSEDEEGWKKFCLGE |
| O14974 | S912 | Sugiyama | PPP1R12A MBS MYPT1 | TssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDSTDF |
| O15067 | S407 | Sugiyama | PFAS KIAA0361 | NGASDYGNKFGEPVLAGFARsLGLQLPDGQRREWIKPIMFS |
| O15067 | S513 | Sugiyama | PFAS KIAA0361 | QKMNRVIRACVEAPKGNPICsLHDQGAGGNGNVLKELsDPA |
| O15427 | S464 | Sugiyama | SLC16A3 MCT3 MCT4 | EHFLKAEPEKNGEVVHtPEtsV___________________ |
| O43164 | S196 | Sugiyama | PJA2 KIAA0438 RNF131 | EDNDHLQLSAEVVEGSRYQEsLGNtVFELENREAEAYtGLs |
| O43175 | S14 | Sugiyama | PHGDH PGDH3 | _______MAFANLRKVLIsDsLDPCCRKILQDGGLQVVEKQ |
| O43175 | S251 | Sugiyama | PHGDH PGDH3 | VVNCARGGIVDEGALLRALQsGQCAGAALDVFTEEPPRDRA |
| O43290 | S117 | Sugiyama | SART1 | KRDDGYEAAASSKtssGDAssLSIEETNKLRAKLGLKPLEV |
| O43423 | S100 | Sugiyama | ANP32CP PP32R1 | AEKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCE |
| O43524 | S644 | SIGNOR|EPSD|PSP | FOXO3 FKHRL1 FOXO3A | MEsIIRSELMDADGLDFNFDsLISTQNVVGLNVGNFTGAKQ |
| O43615 | S193 | Sugiyama | TIMM44 MIMT44 TIM44 | TAAFRALsQGVEsVKKEIDDsVLGQtGPyRRPQRLRKRTEF |
| O43670 | S371 | Sugiyama | ZNF207 BUGZ | PATLTTtsAtsKLIHPDEDIsLEERRAQLPKYQRNLPRPGQ |
| O43707 | S507 | Sugiyama | ACTN4 | DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID |
| O43707 | S796 | Sugiyama | ACTN4 | HFDKDHGGALGPEEFKACLIsLGyDVENDRQGEAEFNRIMS |
| O43734 | S328 | SIGNOR | TRAF3IP2 C6orf2 C6orf4 C6orf5 C6orf6 | LPGASVRGLHPVQKVILNYPsPWDHEERPAQRDCSFPGLPR |
| O43852 | S125 | Sugiyama | CALU | IyEDVERQWKGHDLNEDGLVsWEEyKNATYGYVLDDPDPDD |
| O43852 | S219 | Sugiyama | CALU | DIDKNADGFIDLEEyIGDMysHDGNtDEPEWVKTEREQFVE |
| O43852 | S261 | Sugiyama | CALU | RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK |
| O43852 | S44 | Sugiyama | CALU | KKDRVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQL |
| O43852 | T196 | Sugiyama | CALU | FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD |
| O60291 | S515 | Sugiyama | MGRN1 KIAA0544 RNF156 | sFItEEVDESssPQQGTRAAsIENVLQDssPEHCGRGPPAD |
| O60664 | S225 | Sugiyama | PLIN3 M6PRBP1 TIP47 | PLTDAELARIAtsLDGFDVAsVQQQRQEQSyFVRLGsLSER |
| O60664 | S91 | Sugiyama | PLIN3 M6PRBP1 TIP47 | TAAAVsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQ |
| O60664 | T216 | Sugiyama | PLIN3 M6PRBP1 TIP47 | sEEWADNHLPLTDAELARIAtsLDGFDVAsVQQQRQEQSyF |
| O60784 | S355 | Sugiyama | TOM1 | LSSQLAGMNLGSSSVRAGLQsLEAsGRLEDEFDMFALTRGS |
| O60841 | S190 | Sugiyama | EIF5B IF2 KIAA0741 | NsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGP |
| O60841 | S222 | Sugiyama | EIF5B IF2 KIAA0741 | KNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAEKKERERKK |
| O75347 | S103 | Sugiyama | TBCA | ENEKDLEEAEEyKEARLVLDsVKLEA_______________ |
| O75643 | S17 | Sugiyama | SNRNP200 ASCC3L1 BRR2 HELIC2 KIAA0788 | ____MADVTARsLQYEYKANsNLVLQADRsLIDRTRRDEPT |
| O75643 | S26 | Sugiyama | SNRNP200 ASCC3L1 BRR2 HELIC2 KIAA0788 | ARsLQYEYKANsNLVLQADRsLIDRTRRDEPTGEVLsLVGK |
| O75643 | S42 | Sugiyama | SNRNP200 ASCC3L1 BRR2 HELIC2 KIAA0788 | QADRsLIDRTRRDEPTGEVLsLVGKLEGTRMGDKAQRTKPQ |
| O75821 | S189 | Sugiyama | EIF3G EIF3S4 | CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK |
| O75828 | S69 | Sugiyama | CBR3 SDR21C2 | QLQAEGLsPRFHQLDIDDLQsIRALRDFLRKEYGGLNVLVN |
| O94776 | S433 | Sugiyama | MTA2 MTA1L1 PID | ATRGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQt |
| O94992 | S268 | Sugiyama | HEXIM1 CLP1 EDG1 HIS1 MAQ1 | EDGGsDGMGGDGSEFLQRDFsEtyERyHTEsLQNMsKQELI |
| O94992 | T270 | Sugiyama | HEXIM1 CLP1 EDG1 HIS1 MAQ1 | GGsDGMGGDGSEFLQRDFsEtyERyHTEsLQNMsKQELIKE |
| O95155 | S105 | Sugiyama | UBE4B HDNB1 KIAA0684 UFD2 | LsssPsNsLEtQsQsLsRsQsMDIDGVSCEKsMsQVDVDsG |
| O95218 | S143 | Sugiyama | ZRANB2 ZIS ZNF265 | EyDEFGRKKKKYRGKAVGPAsILKEVEDKEsEGEEEDEDED |
| O95218 | S181 | Sugiyama | ZRANB2 ZIS ZNF265 | DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR |
| O95292 | S9 | Sugiyama | VAPB UNQ484/PRO983 | ____________MAKVEQVLsLEPQHELKFRGPFTDVVTTN |
| O95297 | S260 | Sugiyama | MPZL1 PZR UNQ849/PRO1787 | IyAQLDHsGGHHSDKINKSEsVVyADIRKN___________ |
| O95626 | S104 | Sugiyama | ANP32D PP32R2 | AEKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCE |
| O95644 | S117 | EPSD|PSP | NFATC1 NFAT2 NFATC | PAGYFLSSGHTRPDGAPALEsPRIEITSCLGLYHNNNQFFH |
| O95644 | S151 | SIGNOR|EPSD|PSP | NFATC1 NFAT2 NFATC | NNNQFFHDVEVEDVLPSSKRsPstATLSLPsLEAYRDPsCL |
| O95644 | S161 | EPSD|PSP | NFATC1 NFAT2 NFATC | VEDVLPSSKRsPstATLSLPsLEAYRDPsCLsPAssLSSRS |
| O95644 | S324 | EPSD|PSP | NFATC1 NFAT2 NFATC | TTQYTSSAIVAAINALTTDSsLDLGDGVPVKsRKttLEQPP |
| O95678 | S162 | Sugiyama | KRT75 K6HF KB18 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| O95757 | S587 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM |
| O95757 | S599 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND |
| O95786 | S855 | EPSD|PSP | RIGI DDX58 | GDAFKECFVSRPHPKPKQFssFEKRAKIFCARQNCSHDWGI |
| O95816 | S31 | Sugiyama | BAG2 | NEGRFCRsssMADRsSRLLEsLDQLELRVEALREAATAVEQ |
| O96013 | S41 | Sugiyama | PAK4 KIAA1142 | VHTGFDQHEQKFTGLPRQWQsLIEESARRPKPLVDPACITS |
| P00338 | S319 | Sugiyama | LDHA PIG19 | GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______ |
| P00441 | S106 | Sugiyama | SOD1 | GNVtADKDGVADVsIEDsVIsLsGDHCIIGRTLVVHEKADD |
| P00441 | S99 | Sugiyama | SOD1 | ERHVGDLGNVtADKDGVADVsIEDsVIsLsGDHCIIGRTLV |
| P00558 | S390 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | IIGGGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPG |
| P00558 | S399 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__ |
| P00558 | T168 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF |
| P02538 | S176 | Sugiyama | KRT6A K6A KRT6D | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT |
| P02545 | S463 | Sugiyama | LMNA LMN1 | EEVDEEGKFVRLRNKsNEDQsMGNWQIKRQNGDDPLLtYRF |
| P02786 | S10 | Sugiyama | TFRC | ___________MMDQARsAFsNLFGGEPLsytRFsLARQVD |
| P02786 | S24 | Sugiyama | TFRC | QARsAFsNLFGGEPLsytRFsLARQVDGDNsHVEMKLAVDE |
| P03372 | S167 | SIGNOR|EPSD|PSP | ESR1 ESR NR3A1 | PAFYRPNsDNRRQGGRERLAsTNDKGSMAMESAKETRYCAV |
| P04075 | S17 | Sugiyama | ALDOA ALDA | ____MPyQyPALtPEQKKELsDIAHRIVAPGKGILAADEst |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S354 | Sugiyama | ALDOA ALDA | ANsLACQGKytPsGQAGAAAsEsLFVsNHAy__________ |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S360 | Sugiyama | ALDOA ALDA | QGKytPsGQAGAAAsEsLFVsNHAy________________ |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | Y364 | Sugiyama | ALDOA ALDA | tPsGQAGAAAsEsLFVsNHAy____________________ |
| P04083 | S189 | Sugiyama | ANXA1 ANX1 LPC1 | tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA |
| P04083 | T172 | Sugiyama | ANXA1 ANX1 LPC1 | INRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDF |
| P04259 | S176 | Sugiyama | KRT6B K6B KRTL1 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P04406 | S151 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | FVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIV |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | T154 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIVEGL |
| P04406 | Y314 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S64 | Sugiyama | RPLP2 D11S2243E RPP2 | sELNGKNIEDVIAQGIGKLAsVPAGGAVAVsAAPGsAAPAA |
| P05455 | S225 | Sugiyama | SSB | LRAKQEQEAKQKLEEDAEMKsLEEKIGCLLKFSGDLDDQTC |
| P05455 | S325 | Sugiyama | SSB | VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA |
| P05783 | S93 | Sugiyama | KRT18 CYK18 PIG46 | GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR |
| P05787 | S104 | Sugiyama | KRT8 CYK8 | IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS |
| P05787 | S258 | Sugiyama | KRT8 CYK8 | QISDTSVVLsMDNSRsLDMDsIIAEVKAQyEDIANRsRAEA |
| P05787 | S280 | Sugiyama | KRT8 CYK8 | IAEVKAQyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDL |
| P05787 | S291 | Sugiyama | KRT8 CYK8 | ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN |
| P05787 | S330 | Sugiyama | KRT8 CYK8 | MNRNISRLQAEIEGLKGQRAsLEAAIADAEQRGELAIKDAN |
| P05787 | S410 | Sugiyama | KRT8 CYK8 | TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S291 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA |
| P06733 | S353 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06748 | S137 | Sugiyama | NPM1 NPM | VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK |
| P06748 | S43 | Sugiyama | NPM1 NPM | LKADKDyHFKVDNDENEHQLsLRTVsLGAGAKDELHIVEAE |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | S320 | Sugiyama | LDHB | GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______ |
| P07195 | S44 | Sugiyama | LDHB | ITVVGVGQVGMACAISILGKsLADELALVDVLEDKLKGEMM |
| P07195 | T323 | Sugiyama | LDHB | sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________ |
| P07203 | S95 | Sugiyama | GPX1 | GFPCNQFGHQENAKNEEILNsLKyVRPGGGFEPNFMLFEKC |
| P07205 | S390 | Sugiyama | PGK2 PGKB | VIGGGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPG |
| P07205 | S399 | Sugiyama | PGK2 PGKB | CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__ |
| P07205 | T168 | Sugiyama | PGK2 PGKB | EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF |
| P07237 | S427 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | WDKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFP |
| P07237 | T85 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | KAAGKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFF |
| P07355 | S127 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | AQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEINRVy |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07437 | S115 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL |
| P07437 | S75 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| P07737 | S30 | Sugiyama | PFN1 | NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV |
| P07737 | S85 | Sugiyama | PFN1 | tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK |
| P07737 | T65 | Sugiyama | PFN1 | PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs |
| P07737 | Y60 | Sugiyama | PFN1 | FVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQ |
| P07814 | S1473 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | CEDWIKKtTARDQDLEPGAPsMGAKSLCIPFKPLCELQPGA |
| P07814 | S739 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV |
| P07814 | S750 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | APFKERPtPsLNNNCttsEDsLVLyNRVAVQGDVVRELKAK |
| P07814 | S944 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PKDQVDIAVQELLQLKAQYKsLIGVEyKPVsATGAEDKDKK |
| P07900 | S476 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | RKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKHIyyItG |
| P07900 | S50 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | S63 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN |
| P07900 | S641 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD |
| P08195 | S134 | Sugiyama | SLC3A2 MDU1 | ELNELEPEKQPMNAAsGAAMsLAGAEKNGLVKIKVAEDEAE |
| P08195 | S292 | Sugiyama | SLC3A2 MDU1 | VAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNY |
| P08195 | S518 | Sugiyama | SLC3A2 MDU1 | DIPGAVSANMTVKGQsEDPGsLLsLFRRLsDQRsKERSLLH |
| P08195 | S521 | Sugiyama | SLC3A2 MDU1 | GAVSANMTVKGQsEDPGsLLsLFRRLsDQRsKERSLLHGDF |
| P08238 | S206 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEDQtEyLEERRVKEVVKKHsQFIGyPItLyLEKEREKEIs |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S48 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG |
| P08238 | S482 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | sGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVER |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | S58 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| P08238 | T214 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EERRVKEVVKKHsQFIGyPItLyLEKEREKEIsDDEAEEEK |
| P08670 | S205 | Sugiyama | VIM | LREKLQEEMLQREEAENtLQsFRQDVDNAsLARLDLERKVE |
| P08670 | S325 | Sugiyama | VIM | NNDALRQAKQESTEYRRQVQsLtCEVDALKGtNEsLERQMR |
| P08670 | S430 | Sugiyama | VIM | RIsLPLPNFssLNLREtNLDsLPLVDtHsKRTLLIKtVEtR |
| P08708 | S89 | Sugiyama | RPS17 RPS17L | ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL |
| P08729 | S104 | Sugiyama | KRT7 SCL | LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT |
| P08758 | T10 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | ___________MAQVLRGtVtDFPGFDERADAEtLRKAMKG |
| P08865 | S138 | Sugiyama | RPSA LAMBR LAMR1 | EPRLLVVTDPRADHQPLtEAsyVNLPtIALCNTDSPLRyVD |
| P08865 | S75 | Sugiyama | RPSA LAMBR LAMR1 | WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG |
| P08865 | S78 | Sugiyama | RPSA LAMBR LAMR1 | LLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtP |
| P08865 | T144 | Sugiyama | RPSA LAMBR LAMR1 | VTDPRADHQPLtEAsyVNLPtIALCNTDSPLRyVDIAIPCN |
| P09234 | S48 | Sugiyama | SNRPC | RKHKENVKDYYQKWMEEQAQsLIDKTTAAFQQGKIPPTPFS |
| P09382 | T58 | Sugiyama | LGALS1 | DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF |
| P09429 | S35 | Sugiyama | HMGB1 HMG1 | syAFFVQtCREEHKKKHPDAsVNFsEFsKKCsERWKtMsAK |
| P09493 | T282 | Sugiyama | TPM1 C15orf13 TMSA | AQKLKYKAISEELDHALNDMtsI__________________ |
| P09496 | S236 | Sugiyama | CLTA | RLCDFNPKSSKQAKDVSRMRsVLIsLKQAPLVH________ |
| P09496 | S240 | Sugiyama | CLTA | FNPKSSKQAKDVSRMRsVLIsLKQAPLVH____________ |
| P09651 | S360 | Sugiyama | HNRNPA1 HNRPA1 | PyGGGGQyFAKPRNQGGyGGssssssyGsGRRF________ |
| P09651 | S368 | Sugiyama | HNRNPA1 HNRPA1 | FAKPRNQGGyGGssssssyGsGRRF________________ |
| P09651 | Y357 | Sugiyama | HNRNPA1 HNRPA1 | ssGPyGGGGQyFAKPRNQGGyGGssssssyGsGRRF_____ |
| P09972 | S356 | Sugiyama | ALDOC ALDC | GLAAQGKYEGSGEDGGAAAQsLyIANHAY____________ |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0DPH7 | S48 | Sugiyama | TUBA3C TUBA2 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P0DPH7 | S54 | Sugiyama | TUBA3C TUBA2 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P0DPH7 | T41 | Sugiyama | TUBA3C TUBA2 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| P0DPH7 | T51 | Sugiyama | TUBA3C TUBA2 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P10809 | S453 | Sugiyama | HSPD1 HSP60 | EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK |
| P10809 | S488 | Sugiyama | HSPD1 HSP60 | IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG |
| P10809 | S67 | Sugiyama | HSPD1 HSP60 | LADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLK |
| P10809 | T61 | Sugiyama | HSPD1 HSP60 | LQGVDLLADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVA |
| P10914 | S215 | SIGNOR|EPSD|PSP | IRF1 | WHIPVEVVPDSTSDLYNFQVsPMPsTsEATTDEDEEGKLPE |
| P10914 | S219 | SIGNOR|EPSD|PSP | IRF1 | VEVVPDSTSDLYNFQVsPMPsTsEATTDEDEEGKLPEDIMK |
| P10914 | S221 | SIGNOR|EPSD|PSP | IRF1 | VVPDSTSDLYNFQVsPMPsTsEATTDEDEEGKLPEDIMKLL |
| P11047 | S942 | Sugiyama | LAMC1 LAMB2 | GFYNLQSGQGCERCDCHALGstNGQCDIRTGQCECQPGITG |
| P11142 | S362 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | RIPKIQKLLQDFFNGKELNKsINPDEAVAyGAAVQAAILsG |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | T163 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy |
| P11142 | T226 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK |
| P11279 | S141 | Sugiyama | LAMP1 | NLSDTHLFPNASSKEIKtVEsITDIRADIDKKYRCVSGTQV |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P12004 | S152 | Sugiyama | PCNA | EySCVVKMPSGEFARICRDLsHIGDAVVIsCAKDGVKFSAs |
| P12004 | S161 | Sugiyama | PCNA | SGEFARICRDLsHIGDAVVIsCAKDGVKFSAsGELGNGNIK |
| P12035 | S211 | Sugiyama | KRT3 | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN |
| P12268 | S505 | Sugiyama | IMPDH2 IMPD2 | SGELKFEKRtssAQVEGGVHsLHsyEKRLF___________ |
| P12268 | S508 | Sugiyama | IMPDH2 IMPD2 | LKFEKRtssAQVEGGVHsLHsyEKRLF______________ |
| P12270 | T1039 | Sugiyama | TPR | QDDKRRAIESMEQQLSELKKtLSSVQNEVQEALQRASTALS |
| P12277 | S163 | Sugiyama | CKB CKBB | PPHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAE |
| P13073 | S34 | Sugiyama | COX4I1 COX4 | AISTSVCVRAHESVVKsEDFsLPAyMDRRDHPLPEVAHVKH |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S38 | Sugiyama | EEF2 EF2 | NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD |
| P13639 | S587 | Sugiyama | EEF2 EF2 | CIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKAR |
| P13647 | S181 | Sugiyama | KRT5 | IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P13667 | Y565 | Sugiyama | PDIA4 ERP70 ERP72 | DVLIEFYAPWCGHCKQLEPVyNsLAKKYKGQKGLVIAKMDA |
| P13693 | S9 | Sugiyama | TPT1 | ____________MIIYRDLIsHDEMFsDIyKIREIADGLCL |
| P13797 | Y121 | Sugiyama | PLS3 | EGICALGGTsELssEGtQHsysEEEKyAFVNWINKALENDP |
| P13861 | S58 | Sugiyama | PRKAR2A PKR2 PRKAR2 | TRLREARAPAsVLPAAtPRQsLGHPPPEPGPDRVADAKGDs |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P14209 | S168 | Sugiyama | CD99 MIC2 MIC2X MIC2Y | YQKKKLCFKENAEQGEVDMEsHRNANAEPAVQRtLLEK___ |
| P14314 | S126 | Sugiyama | PRKCSH G19P1 | yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE |
| P14314 | S168 | Sugiyama | PRKCSH G19P1 | WKKAREEKQKKLIELQAGKKsLEDQVEMLRTVKEEAEKPER |
| P14314 | T469 | Sugiyama | PRKCSH G19P1 | WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt |
| P14618 | S100 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | tHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGPEIR |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S97 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGP |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S109 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN |
| P14625 | S523 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | RtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAG |
| P14625 | S674 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | WsGNMERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLI |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14854 | S52 | Sugiyama | COX6B1 COX6B | QNyLDFHRCQKAMTAKGGDIsVCEWyQRVYQsLCPtsWVTD |
| P14854 | S68 | Sugiyama | COX6B1 COX6B | GGDIsVCEWyQRVYQsLCPtsWVTDWDEQRAEGTFPGKI__ |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15311 | S536 | Sugiyama | EZR VIL2 | KRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNE |
| P15311 | S539 | Sugiyama | EZR VIL2 | TEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNENMR |
| P15311 | T533 | Sugiyama | EZR VIL2 | NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P16070 | S71 | Sugiyama | CD44 LHR MDU2 MDU3 MIC4 | DLCKAFNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRI |
| P16083 | S80 | Sugiyama | NQO2 NMOR2 | LSNPEVFNyGVEtHEAyKQRsLAsDITDEQKKVREADLVIF |
| P16083 | S83 | Sugiyama | NQO2 NMOR2 | PEVFNyGVEtHEAyKQRsLAsDITDEQKKVREADLVIFQFP |
| P16152 | S69 | Sugiyama | CBR1 CBR CRN SDR21C1 | QLQAEGLsPRFHQLDIDDLQsIRALRDFLRKEYGGLDVLVN |
| P16333 | S96 | Sugiyama | NCK1 NCK | GIGKVKRKPsVPDsAsPADDsFVDPGERLyDLNMPAyVKFN |
| P16949 | S46 | Sugiyama | STMN1 C1orf215 LAP18 OP18 | PRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAEERRKsHEA |
| P17066 | S42 | Sugiyama | HSPA6 HSP70B' | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P17812 | S587 | Sugiyama | CTPS1 CTPS | ysDRsGsssPDsEItELKFPsINHD________________ |
| P17844 | S520 | Sugiyama | DDX5 G17P1 HELR HLR1 | GKRGGFNTFRDRENYDRGYssLLKRDFGAKTQNGVYSAANY |
| P17987 | S35 | Sugiyama | TCP1 CCT1 CCTA | EtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTIT |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P18615 | S135 | Sugiyama | NELFE RD RDBP | sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG |
| P18615 | S138 | Sugiyama | NELFE RD RDBP | DDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEGPGA |
| P18615 | Y133 | Sugiyama | NELFE RD RDBP | sIsADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEA |
| P18621 | S111 | Sugiyama | RPL17 | LLHMLKNAESNAELKGLDVDsLVIEHIQVNKAPKMRRRTYR |
| P18621 | S5 | Sugiyama | RPL17 | ________________MVRysLDPENPtKsCKSRGSNLRVH |
| P18669 | S134 | Sugiyama | PGAM1 PGAMA CDABP0006 | IWRRsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsCE |
| P18669 | S152 | Sugiyama | PGAM1 PGAMA CDABP0006 | FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV |
| P18669 | S155 | Sugiyama | PGAM1 PGAMA CDABP0006 | NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI |
| P18827 | S287 | Sugiyama | SDC1 SDC | AVCLVGFMLYRMKKKDEGsysLEEPKQANGGAyQKPtKQEE |
| P19338 | S458 | Sugiyama | NCL | TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P19338 | S619 | Sugiyama | NCL | RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK |
| P20042 | S67 | Sugiyama | EIF2S2 EIF2B | EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK |
| P20290 | S126 | Sugiyama | BTF3 NACB OK/SW-cl.8 | VNMFTNQGTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEM |
| P20290 | T133 | Sugiyama | BTF3 NACB OK/SW-cl.8 | GTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQ |
| P20618 | S151 | Sugiyama | PSMB1 PSC5 | PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA |
| P20618 | S162 | Sugiyama | PSMB1 PSC5 | DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG |
| P20810 | S295 | Sugiyama | CAST | QEKKRKVEKDtMsDQALEALsAsLGTRQAEPELDLRsIKEV |
| P20810 | S297 | Sugiyama | CAST | KKRKVEKDtMsDQALEALsAsLGTRQAEPELDLRsIKEVDE |
| P21333 | S1029 | Sugiyama | FLNA FLN FLN1 | VGPSGAAVPCKVEPGLGADNsVVRFLPREEGPYEVEVTYDG |
| P22059 | S386 | Sugiyama | OSBP OSBP1 | ITMPENLGHKRtGsNIsGAssDIsLDEQyKHQLEETKKEKR |
| P22059 | S389 | Sugiyama | OSBP OSBP1 | PENLGHKRtGsNIsGAssDIsLDEQyKHQLEETKKEKRTRI |
| P22626 | S225 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN |
| P23381 | S358 | Sugiyama | WARS1 IFI53 WARS WRS | TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs |
| P23528 | T70 | Sugiyama | CFL1 CFL | EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE |
| P23588 | S122 | Sugiyama | EIF4B | NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA |
| P23588 | S207 | Sugiyama | EIF4B | DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR |
| P23921 | S780 | Sugiyama | RRM1 RR1 | KEKVSKEEEEKERNtAAMVCsLENRDECLMCGS________ |
| P24752 | S218 | Sugiyama | ACAT1 ACAT MAT | ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV |
| P25205 | S41 | Sugiyama | MCM3 | DFLDDEEDQGIyQsKVRELIsDNQyRLIVNVNDLRRKNEKR |
| P25205 | S704 | Sugiyama | MCM3 | DQEQKRKRRKTRQPDAKDGDsyDPyDFsDtEEEMPQVHtPK |
| P25705 | S198 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK |
| P25705 | S53 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | ARNFHASNTHLQKtGtAEMssILEERILGADtsVDLEETGR |
| P25705 | S65 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | KtGtAEMssILEERILGADtsVDLEETGRVLsIGDGIARVH |
| P25786 | S211 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | GLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDDDDVsP |
| P25788 | Y239 | Sugiyama | PSMA3 HC8 PSC8 | ELTNGRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM____ |
| P25963 | S32 | GPS6|EPSD|PSP | NFKBIA IKBA MAD3 NFKBI | AMEGPRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEI |
| P25963 | S36 | GPS6|SIGNOR|iPTMNet|EPSD|PSP | NFKBIA IKBA MAD3 NFKBI | PRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEIRLEP |
| P26038 | S527 | Sugiyama | MSN | ERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHAE |
| P26038 | S576 | Sugiyama | MSN | YKtLRQIRQGNTKQRIDEFEsM___________________ |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26639 | S522 | Sugiyama | TARS1 TARS | PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP |
| P27348 | S45 | Sugiyama | YWHAQ | CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI |
| P27482 | S18 | Sugiyama | CALML3 | ___MADQLTEEQVTEFKEAFsLFDKDGDGCITTRELGTVMR |
| P27695 | S129 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | QELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDE |
| P27797 | S195 | Sugiyama | CALR CRTC | IVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIKDPDAsK |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P28066 | S180 | Sugiyama | PSMA5 | GtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSLI |
| P28340 | S1042 | Sugiyama | POLD1 POLD | QGAVCEFCQPRESELYQKEVsHLNALEERFSRLWTQCQRCQ |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | S305 | Sugiyama | TKT | LAtPPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQAL |
| P29401 | S439 | Sugiyama | TKT | VSIGEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVE |
| P29401 | T442 | Sugiyama | TKT | GEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAA |
| P29590 | S366 | Sugiyama | PML MYL PP8675 RNF71 TRIM19 | LDMHGFLRQALCRLRQEEPQsLQAAVRTDGFDEFKVRLQDL |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S60 | Sugiyama | EEF1D EF1D | ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL |
| P29692 | S86 | Sugiyama | EEF1D EF1D | GPGAssGtsGDHGELVVRIAsLEVENQsLRGVVQELQQAIs |
| P30043 | S198 | Sugiyama | BLVRB FLR SCAN | KHDLGHFMLRCLttDEyDGHstyPsHQyQ____________ |
| P30043 | S202 | Sugiyama | BLVRB FLR SCAN | GHFMLRCLttDEyDGHstyPsHQyQ________________ |
| P30043 | Y200 | Sugiyama | BLVRB FLR SCAN | DLGHFMLRCLttDEyDGHstyPsHQyQ______________ |
| P30044 | S168 | Sugiyama | PRDX5 ACR1 SBBI10 | RLLADPTGAFGKEtDLLLDDsLVsIFGNRRLKRFsMVVQDG |
| P30044 | S171 | Sugiyama | PRDX5 ACR1 SBBI10 | ADPTGAFGKEtDLLLDDsLVsIFGNRRLKRFsMVVQDGIVK |
| P30044 | T161 | Sugiyama | PRDX5 ACR1 SBBI10 | HKAEGKVRLLADPTGAFGKEtDLLLDDsLVsIFGNRRLKRF |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30050 | S157 | Sugiyama | RPL12 | QsVGCNVDGRHPHDIIDDINsGAVECPAs____________ |
| P30086 | S104 | Sugiyama | PEBP1 PBP PEBP | WHHFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLHRyVWLV |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | S60 | Sugiyama | PEBP1 PBP PEBP | VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK |
| P30086 | T51 | Sugiyama | PEBP1 PBP PEBP | GAAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDP |
| P30086 | T65 | Sugiyama | PEBP1 PBP PEBP | QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH |
| P30101 | S474 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | yFsPANKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEK |
| P30101 | S478 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | ANKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKK |
| P30101 | S98 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | VPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGP |
| P30101 | T102 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRtAD |
| P30101 | Y100 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | LAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRt |
| P30740 | S72 | Sugiyama | SERPINB1 ELANH2 MNEI PI2 | AQLSKTFHFNTVEEVHSRFQsLNADINKRGASYILKLANRL |
| P31327 | S564 | Sugiyama | CPS1 | TEDRQLFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPV |
| P31327 | S569 | Sugiyama | CPS1 | LFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPVMIRSA |
| P31327 | S863 | Sugiyama | CPS1 | LSEPSsTRIyAIAKAIDDNMsLDEIEKLTYIDKWFLYKMRD |
| P31749 | S473 | EPSD|PSP | AKT1 PKB RAC | DQDDSMECVDSERRPHFPQFsysAsGtA_____________ |
| P31749 | T308 | EPSD|PSP | AKT1 PKB RAC | IKITDFGLCKEGIKDGAtMKtFCGtPEyLAPEVLEDNDyGR |
| P31943 | S269 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH |
| P31943 | S272 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | GYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGHCVH |
| P31943 | S281 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | GRDLNyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAt |
| P31943 | S285 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | NyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDI |
| P31943 | T286 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | yCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDIy |
| P31946 | S47 | Sugiyama | YWHAB | AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P31947 | S45 | Sugiyama | SFN HME1 | FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI |
| P33240 | S336 | Sugiyama | CSTF2 | PtPRGLLGDAPNDPRGGtLLsVtGEVEPRGYLGPPHQGPPM |
| P34897 | S52 | Sugiyama | SHMT2 | AQTQTGEANRGWtGQEsLsDsDPEMWELLQREKDRQCRGLE |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P35269 | S431 | Sugiyama | GTF2F1 RAP74 | GKRVSEMPAAKRLRLDtGPQsLsGKstPQPPsGKttPNsGD |
| P35579 | S1308 | Sugiyama | MYH9 | LLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLs |
| P35579 | S169 | Sugiyama | MYH9 | HIyAITDtAyRSMMQDREDQsILCTGESGAGKTENTKKVIQ |
| P35579 | S1915 | Sugiyama | MYH9 | KLQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMA |
| P35580 | S1312 | Sugiyama | MYH10 | VsTLLEEAEKKGIKFAKDAAsLEsQLQDtQELLQEETRQKL |
| P35606 | S350 | Sugiyama | COPB2 | MGDAEIKDGERLPLAVKDMGsCEIyPQtIQHNPNGRFVVVC |
| P35908 | S191 | Sugiyama | KRT2 KRT2A KRT2E | IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| P37802 | S145 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN |
| P37802 | S163 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG |
| P37802 | T180 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_ |
| P38606 | S614 | Sugiyama | ATP6V1A ATP6A1 ATP6V1A1 VPP2 | EAKIKSDYAQLLEDMQNAFRsLED_________________ |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P38646 | T94 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN |
| P39019 | S90 | Sugiyama | RPS19 | AGVGsMTKIYGGRQRNGVMPsHFsRGsKsVARRVLQALEGL |
| P39023 | S13 | Sugiyama | RPL3 OK/SW-cl.32 | ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP |
| P39687 | S104 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | AEKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCE |
| P39687 | S117 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | GNKIKDLstIEPLKKLENLKsLDLFNCEVtNLNDyRENVFK |
| P41238 | S8 | Sugiyama | APOBEC1 | _____________MTSEKGPsTGDPtLRRRIEPWEFDVFYD |
| P41238 | T13 | Sugiyama | APOBEC1 | ________MTSEKGPsTGDPtLRRRIEPWEFDVFYDPRELR |
| P42224 | S727 | SIGNOR | STAT1 | IsVsEVHPSRLQttDNLLPMsPEEFDEVSRIVGsVEFDSMM |
| P42566 | S655 | Sugiyama | EPS15 AF1P | PFGKIDPFGGDPFKGSDPFAsDCFFRQSTDPFAtsstDPFs |
| P42858 | S13 | PSP | HTT HD IT15 | ________MAtLEKLMKAFEsLKsFQQQQQQQQQQQQQQQQ |
| P43243 | S188 | Sugiyama | MATR3 KIAA0723 | EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs |
| P43243 | S195 | Sugiyama | MATR3 KIAA0723 | RDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyD |
| P43243 | S211 | Sugiyama | MATR3 KIAA0723 | DRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDDRLRDGERCR |
| P43243 | S234 | Sugiyama | MATR3 KIAA0723 | yDRMDyEDDRLRDGERCRDDsFFGEtsHNyHKFDsEyERMG |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P45974 | S783 | Sugiyama | USP5 ISOT | IDDLDAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQL |
| P45974 | S785 | Sugiyama | USP5 ISOT | DLDAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQLFA |
| P45974 | S787 | Sugiyama | USP5 ISOT | DAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQLFAFI |
| P46013 | S1098 | Sugiyama | MKI67 | PAARVTGMKKWPRtPKEEAQsLEDLAGFKELFQtPGPsEEs |
| P46776 | Y108 | Sugiyama | RPL27A | VNAAKNKtGAAPIIDVVRsGyyKVLGKGKLPKQPVIVKAKF |
| P46777 | S172 | Sugiyama | RPL5 MSTP030 | RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA |
| P46937 | S419 | SIGNOR|EPSD|PSP | YAP1 YAP65 | DsGLsMssysVPRtPDDFLNsVDEMDTGDTINQSTLPsQQN |
| P46940 | S1362 | Sugiyama | IQGAP1 KIAA0051 | GESSGNLNDPNKEALAKTEVsLTLTNKFDVPGDENAEMDAR |
| P47712 | S729 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA |
| P47756 | S192 | Sugiyama | CAPZB | TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN |
| P47914 | S142 | Sugiyama | RPL29 | KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___ |
| P48643 | S270 | Sugiyama | CCT5 CCTE KIAA0098 | ILTCPFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQ |
| P48668 | S176 | Sugiyama | KRT6C KRT6E | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P48739 | S165 | Sugiyama | PITPNB | DRSQVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsP |
| P48741 | S42 | Sugiyama | HSPA7 HSP70B | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P49023 | S83 | Sugiyama | PXN | LDPLDQWQPSSSRFIHQQPQsssPVyGssAKtssVsNPQDs |
| P49368 | S244 | Sugiyama | CCT3 CCTG TRIC5 | VTHPRMRRYIKNPRIVLLDssLEyKKGEsQtDIEITREEDF |
| P49589 | S305 | Sugiyama | CARS1 CARS | KLVPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKA |
| P49736 | S170 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | KRRQVERAtEDGEEDEEMIEsIENLEDLKGHSVREWVsMAG |
| P49790 | S203 | Sugiyama | NUP153 | ttsGFssRAsDKDITVsKNtsLPPLWsPEAERsHsLsQHtA |
| P49840 | S21 | EPSD|PSP | GSK3A | MsGGGPsGGGPGGsGRARtssFAEPGGGGGGGGGGPGGsAs |
| P49959 | S447 | Sugiyama | MRE11 HNGS1 MRE11A | LRVEDLVKQYFQTAEKNVQLsLLTERGMGEAVQEFVDKEEK |
| P50395 | S401 | Sugiyama | GDI2 RABGDIB | VsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDDIKNIY |
| P50454 | S139 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS |
| P50454 | S141 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI |
| P50454 | Y135 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | LRSLSNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYN |
| P50502 | S181 | Sugiyama | ST13 AAG2 FAM10A1 HIP SNC6 | LQKPNAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| P50897 | S262 | Sugiyama | PPT1 CLN1 PPT | EWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLVF |
| P50991 | S51 | Sugiyama | CCT4 CCTD SRB | AQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtIt |
| P51116 | S601 | Sugiyama | FXR2 FMR1L2 | RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ |
| P51858 | S239 | Sugiyama | HDGF HMG1L2 | DEEEEAtKEDAEAPGIRDHEsL___________________ |
| P52272 | S467 | Sugiyama | HNRNPM HNRPM NAGR1 | VERMGsGIERMGPLGLDHMAssIERMGQTMERIGsGVERMG |
| P52272 | S468 | Sugiyama | HNRNPM HNRPM NAGR1 | ERMGsGIERMGPLGLDHMAssIERMGQTMERIGsGVERMGA |
| P52597 | S265 | Sugiyama | HNRNPF HNRPF | EySGLSDGYGFTTDLFGRDLsyCLsGMyDHRYGDsEFtVQs |
| P52597 | S269 | Sugiyama | HNRNPF HNRPF | LSDGYGFTTDLFGRDLsyCLsGMyDHRYGDsEFtVQsTTGH |
| P52630 | T404 | PSP | STAT2 | KtLtPEKGQsQGLIWDFGYLtLVEQRSGGSGKGSNKGPLGV |
| P52888 | S29 | Sugiyama | THOP1 | GDMADAAsPCSVVNDLRWDLsAQQIEERTRELIEQTKRVyD |
| P52948 | S683 | Sugiyama | NUP98 ADAR2 | IAKPIPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGLEG |
| P53999 | S118 | Sugiyama | SUB1 PC4 RPO2TC1 | PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________ |
| P53999 | S9 | Sugiyama | SUB1 PC4 RPO2TC1 | ____________MPKSKELVsssssGsDsDsEVDKKLKRKK |
| P54105 | S210 | Sugiyama | CLNS1A CLCI ICLN | GMLsQsVssQYNMAGVRtEDsIRDyEDGMEVDttPtVAGQF |
| P54252 | S256 | Sugiyama | ATXN3 ATX3 MJD MJD1 SCA3 | sRQEIDMEDEEADLRRAIQLsMQGssRNIsQDMtQtsGTNL |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P54652 | T229 | Sugiyama | HSPA2 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK |
| P55036 | S358 | Sugiyama | PSMD4 MCB1 | VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_ |
| P55060 | S342 | Sugiyama | CSE1L CAS XPO2 | ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF |
| P55072 | S37 | Sugiyama | VCP HEL-220 HEL-S-70 | LKQKNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTV |
| P55072 | S40 | Sugiyama | VCP HEL-220 HEL-S-70 | KNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTVLLK |
| P55795 | S269 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH |
| P55795 | S272 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | GYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGHCVH |
| P56537 | S174 | Sugiyama | EIF6 EIF3A ITGB4BP OK/SW-cl.27 | FSNQGGLVHPKtsIEDQDELssLLQVPLVAGTVNRGSEVIA |
| P56537 | S175 | Sugiyama | EIF6 EIF3A ITGB4BP OK/SW-cl.27 | SNQGGLVHPKtsIEDQDELssLLQVPLVAGTVNRGSEVIAA |
| P60174 | S21 | Sugiyama | TPI1 TPI | MAPSRKFFVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVV |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | T217 | Sugiyama | TPI1 TPI | VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL |
| P60174 | T28 | Sugiyama | TPI1 TPI | FVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVVCAPPtAy |
| P60174 | T38 | Sugiyama | TPI1 TPI | RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP |
| P60174 | T46 | Sugiyama | TPI1 TPI | IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN |
| P60174 | Y209 | Sugiyama | TPI1 TPI | LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG |
| P60228 | S442 | Sugiyama | EIF3E EIF3S6 INT6 | IEKKLNQNSRSEAPNWAtQDsGFy_________________ |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60709 | S323 | Sugiyama | ACTB | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | S60 | Sugiyama | ACTB | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P60709 | T106 | Sugiyama | ACTB | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P60709 | T249 | Sugiyama | ACTB | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P60709 | T304 | Sugiyama | ACTB | KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst |
| P60709 | T324 | Sugiyama | ACTB | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P60709 | Y53 | Sugiyama | ACTB | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P61158 | S406 | Sugiyama | ACTR3 ARP3 | STPEFYQVCHTKKDyEEIGPsICRHNPVFGVMs________ |
| P61204 | S147 | Sugiyama | ARF3 | KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61604 | S64 | Sugiyama | HSPE1 | AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD |
| P61769 | S75 | Sugiyama | B2M CDABP0092 HDCMA22P | IEVDLLKNGERIEKVEHsDLsFsKDWSFYLLYYTEFTPTEK |
| P61978 | S401 | Sugiyama | HNRNPK HNRPK | GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI |
| P61978 | S420 | Sugiyama | HNRNPK HNRPK | GsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITItGt |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61981 | S38 | Sugiyama | YWHAG | ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS |
| P61981 | S46 | Sugiyama | YWHAG | AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P62136 | S11 | Sugiyama | PPP1CA PPP1A | __________MsDsEKLNLDsIIGRLLEVQGsRPGKNVQLT |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | S46 | Sugiyama | YWHAE | SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI |
| P62304 | S89 | Sugiyama | SNRPE | KSRKQLGRIMLKGDNITLLQsVsN_________________ |
| P62736 | S325 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | S62 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P62736 | T251 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P62736 | T326 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P62736 | Y55 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | S138 | Sugiyama | RPL8 | EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI |
| P62917 | T135 | Sugiyama | RPL8 | CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62942 | T7 | Sugiyama | FKBP1A FKBP1 FKBP12 | ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy |
| P62979 | S123 | Sugiyama | RPS27A UBA80 UBCEP1 | LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK |
| P62979 | S134 | Sugiyama | RPS27A UBA80 UBCEP1 | IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE |
| P62979 | Y140 | Sugiyama | RPS27A UBA80 UBCEP1 | ECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPEDK____ |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | S45 | Sugiyama | YWHAZ | CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI |
| P63104 | T30 | Sugiyama | YWHAZ | AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN |
| P63151 | S412 | Sugiyama | PPP2R2A | LKPRKVCASGKRKKDEIsVDsLDFNKKILHTAWHPKENIIA |
| P63167 | S21 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAH |
| P63220 | S31 | Sugiyama | RPS21 | LYVPRKCSASNRIIGAKDHAsIQMNVAEVDKVTGRFNGQFK |
| P63220 | S68 | Sugiyama | RPS21 | GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____ |
| P63241 | S100 | Sugiyama | EIF5A | DVPNIKRNDFQLIGIQDGyLsLLQDSGEVREDLRLPEGDLG |
| P63261 | S323 | Sugiyama | ACTG1 ACTG | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | S60 | Sugiyama | ACTG1 ACTG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P63261 | T106 | Sugiyama | ACTG1 ACTG | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P63261 | T249 | Sugiyama | ACTG1 ACTG | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P63261 | T304 | Sugiyama | ACTG1 ACTG | KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst |
| P63261 | T324 | Sugiyama | ACTG1 ACTG | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P63261 | Y53 | Sugiyama | ACTG1 ACTG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P63267 | S324 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | S61 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P63267 | T250 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P63267 | T325 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P63267 | Y54 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P67809 | S102 | Sugiyama | YBX1 NSEP1 YB1 | EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA |
| P67809 | S209 | Sugiyama | YBX1 NSEP1 YB1 | RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ |
| P67809 | T108 | Sugiyama | YBX1 NSEP1 YB1 | QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP |
| P67809 | Y99 | Sugiyama | YBX1 NSEP1 YB1 | DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG |
| P68032 | S325 | Sugiyama | ACTC1 ACTC | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | S62 | Sugiyama | ACTC1 ACTC | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68032 | T251 | Sugiyama | ACTC1 ACTC | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68032 | T326 | Sugiyama | ACTC1 ACTC | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68032 | Y55 | Sugiyama | ACTC1 ACTC | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68133 | S325 | Sugiyama | ACTA1 ACTA | TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | S62 | Sugiyama | ACTA1 ACTA | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68133 | T251 | Sugiyama | ACTA1 ACTA | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68133 | T326 | Sugiyama | ACTA1 ACTA | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68133 | Y55 | Sugiyama | ACTA1 ACTA | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68363 | S439 | Sugiyama | TUBA1B | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| P68363 | S48 | Sugiyama | TUBA1B | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P68363 | S54 | Sugiyama | TUBA1B | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P68363 | T41 | Sugiyama | TUBA1B | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| P68363 | T51 | Sugiyama | TUBA1B | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T80 | Sugiyama | TUBA1B | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| P68363 | Y83 | Sugiyama | TUBA1B | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| P78371 | S60 | Sugiyama | CCT2 99D8.1 CCTB | KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA |
| P83731 | S7 | Sugiyama | RPL24 | ______________MKVELCsFsGyKIYPGHGRRYARTDGK |
| P83731 | S86 | Sugiyama | RPL24 | EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE |
| P84077 | S147 | Sugiyama | ARF1 | KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY |
| P84098 | S37 | Sugiyama | RPL19 | CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV |
| P98170 | S430 | EPSD|PSP | XIAP API3 BIRC4 IAP3 | LVADLVNAQKDSMQDESSQTsLQKEISTEEQLRRLQEEKLC |
| Q00839 | S59 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | QAALDDEEAGGRPAMEPGNGsLDLGGDsAGRSGAGLEQEAA |
| Q01105 | S166 | Sugiyama | SET | yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT |
| Q01546 | S196 | Sugiyama | KRT76 KRT2B KRT2P | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE |
| Q02790 | S11 | Sugiyama | FKBP4 FKBP52 | __________MTAEEMKAtEsGAQsAPLPMEGVDIsPKQDE |
| Q02790 | S15 | Sugiyama | FKBP4 FKBP52 | ______MTAEEMKAtEsGAQsAPLPMEGVDIsPKQDEGVLK |
| Q02818 | S193 | Sugiyama | NUCB1 NUC | HEEFKRyEMLKEHERRRyLEsLGEEQRKEAERKLEEQQRRH |
| Q04206 | S468 | GPS6|SIGNOR|EPSD|PSP | RELA NFKB3 | EDLGALLGNSTDPAVFTDLAsVDNsEFQQLLNQGIPVAPHT |
| Q04206 | S536 | GPS6|SIGNOR|ELM|EPSD|PSP | RELA NFKB3 | APLGAPGLPNGLLsGDEDFSsIADMDFsALLSQISS_____ |
| Q04917 | S46 | Sugiyama | YWHAH YWHA1 | AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI |
| Q05682 | S129 | Sugiyama | CALD1 CAD CDM | KRLQEALERQKEFDPtItDAsLsLPsRRMQNDTAENETTEK |
| Q05682 | S131 | Sugiyama | CALD1 CAD CDM | LQEALERQKEFDPtItDAsLsLPsRRMQNDTAENETTEKEE |
| Q06323 | S55 | Sugiyama | PSME1 IFI5111 | KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE |
| Q06830 | S152 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV |
| Q06830 | T156 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | KGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEVCPAG |
| Q06830 | T166 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | DLPVGRsVDEtLRLVQAFQFtDKHGEVCPAGWKPGsDtIKP |
| Q07021 | S210 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS |
| Q07021 | S87 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | CGCGCGSLHTDGDKAFVDFLsDEIKEERKIQKHKTLPKMsG |
| Q07157 | S1139 | Sugiyama | TJP1 ZO1 | HPEESSERGyFPRFEEPAPLsyDsRPRYEQAPRAsALRHEE |
| Q08209 | S492 | Sugiyama | PPP3CA CALNA CNA | EAKGLDRINERMPPRRDAMPsDANLNsINKALTSETNGTDS |
| Q08209 | S498 | Sugiyama | PPP3CA CALNA CNA | RINERMPPRRDAMPsDANLNsINKALTSETNGTDSNGSNSS |
| Q08378 | S465 | Sugiyama | GOLGA3 | LSTKLQAQVECSHSSQQRQDsLsSEVDTLKQsCWDLERAMT |
| Q08752 | S119 | Sugiyama | PPID CYP40 CYPD | yGEKFEDENFHyKHDREGLLsMANAGRNTNGSQFFITTVPT |
| Q09028 | S147 | Sugiyama | RBBP4 RBAP48 | VNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGEC |
| Q09161 | S33 | Sugiyama | NCBP1 CBP80 NCBP | GQPHKRRKtsDANEtEDHLEsLICKVGEKSACSLESNLEGL |
| Q09666 | S295 | Sugiyama | AHNAK PM227 | VPAVDIsssLGGRAVEVQGPsLEsGDHGKIKFPTMKVPKFG |
| Q09666 | S4360 | Sugiyama | AHNAK PM227 | LPKADIEISGPKVDIDAPDVsIEGPDAKLKGPKFKMPEMNI |
| Q12888 | S197 | Sugiyama | TP53BP1 | QsQDVEENTVPYEVDKEQLQsVttNsGytRLsDVDANtAIK |
| Q12906 | S20 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | _MRPMRIFVNDDRHVMAKHssVyPTQEELEAVQNMVsHtER |
| Q12906 | S36 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | AKHssVyPTQEELEAVQNMVsHtERALKAVsDWIDEQEKGs |
| Q12906 | T38 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | HssVyPTQEELEAVQNMVsHtERALKAVsDWIDEQEKGssE |
| Q12933 | S11 | PSP | TRAF2 TRAP3 | __________MAAAsVtPPGsLELLQPGFSKTLLGTKLEAK |
| Q12952 | S174 | Sugiyama | FOXL1 FKHL11 FREAC7 | AKRPRAETHQRSAEAQPEAGsGAGGSGPAISRLQAAPAGPS |
| Q13177 | S141 | Sugiyama | PAK2 | QAVLDVLKFyDsNtVKQKyLsFtPPEKDGFPsGtPALNAKG |
| Q13177 | S55 | Sugiyama | PAK2 | HsLKPLPsVPEEKKPRHKIIsIFsGtEKGsKKKEKERPEIs |
| Q13177 | S58 | Sugiyama | PAK2 | KPLPsVPEEKKPRHKIIsIFsGtEKGsKKKEKERPEIsPPS |
| Q13263 | S784 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK |
| Q13283 | S250 | Sugiyama | G3BP1 G3BP | sssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGI |
| Q13283 | S253 | Sugiyama | G3BP1 G3BP | PAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPH |
| Q13283 | S362 | Sugiyama | G3BP1 G3BP | LFIGNLPHEVDKSELKDFFQsyGNVVELRINsGGKLPNFGF |
| Q13310 | S206 | Sugiyama | PABPC4 APP1 PABP4 | KAKEFtNVyIKNFGEEVDDEsLKELFsQFGKTLSVKVMRDP |
| Q13347 | S217 | Sugiyama | EIF3I EIF3S2 TRIP1 | sRDMtMFVtASKDNTAKLFDsttLEHQKTFRTERPVNSAAL |
| Q13409 | T95 | Sugiyama | DYNC1I2 DNCI2 DNCIC2 | IVFSEYWVPPPMsPSSKsVStPsEAGsQDsGDGAVGsRTLH |
| Q13442 | S57 | Sugiyama | PDAP1 HASPP28 | EEEQKEGGDGAAGDPKKEKKsLDsDEsEDEEDDyQQKRKGV |
| Q13509 | S115 | Sugiyama | TUBB3 TUBB4 | SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL |
| Q13509 | S75 | Sugiyama | TUBB3 TUBB4 | SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS |
| Q13526 | S105 | Sugiyama | PIN1 | ALELINGyIQKIKSGEEDFEsLAsQFSDCSsAKARGDLGAF |
| Q13561 | S203 | Sugiyama | DCTN2 DCTN50 | ATKNSKGGSGGKttGtPPDssLVtyELHsRPEQDKFSQAAK |
| Q13561 | S391 | Sugiyama | DCTN2 DCTN50 | LTQVQTTMRENLATVEGNFAsIDERMKKLGK__________ |
| Q13765 | S132 | Sugiyama | NACA HSD48 | YKSPAsDtyIVFGEAKIEDLsQQAQLAAAEKFKVQGEAVsN |
| Q13885 | S115 | Sugiyama | TUBB2A TUBB2 | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q13885 | S75 | Sugiyama | TUBB2A TUBB2 | AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q14004 | S1048 | Sugiyama | CDK13 CDC2L CDC2L5 CHED KIAA1791 | QKQMGMTDDVSTIKAPRKDLsLGLDDsRtNtPQGVLPSsQL |
| Q14151 | S195 | Sugiyama | SAFB2 KIAA0138 | AQPPEHAVDGEGFKNtLEtssLNFKVtPDIEEsLLEPENEK |
| Q14151 | S613 | Sugiyama | SAFB2 KIAA0138 | ERSSKSQDRKSESKEKRDILsFDKIKEQRERERQRQREREI |
| Q14152 | S1028 | Sugiyama | EIF3A EIF3S10 KIAA0139 | NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP |
| Q14152 | S1188 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PWRPLVKPGGWREKEKAREEsWGPPRESRPsEEREWDREKE |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14152 | S988 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN |
| Q14157 | S852 | Sugiyama | UBAP2L KIAA0144 NICE4 | LDyysIPFPtPttPLtGRDGsLAsNPysGDLtKFGRGDASS |
| Q14157 | S855 | Sugiyama | UBAP2L KIAA0144 NICE4 | ysIPFPtPttPLtGRDGsLAsNPysGDLtKFGRGDASSPAP |
| Q14164 | S151 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | IVHRDIKPGNIMRLVGEEGQsIyKLtDFGAARELDDDEKFV |
| Q14164 | S172 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | IyKLtDFGAARELDDDEKFVsVyGtEEyLHPDMYERAVLRK |
| Q14164 | S479 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | EVARTSLLYLSSSLGTERFSsVAGtPEIQELKAAAELRSRL |
| Q14164 | S519 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | LRtLAEVLSRCSQNITETQEsLSsLNRELVKSRDQVHEDRS |
| Q14164 | S522 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | LAEVLSRCSQNITETQEsLSsLNRELVKSRDQVHEDRSIQQ |
| Q14164 | S582 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | MRPGLGYNEEQIHKLDKVNFsHLAKRLLQVFQEECVQKYQA |
| Q14164 | S603 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | HLAKRLLQVFQEECVQKYQAsLVTHGKRMRVVHETRNHLRL |
| Q14164 | S650 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | ACNTEAQGVQESLSKLLEELsHQLLQDRAKGAQAsPPPIAP |
| Q14164 | S664 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | KLLEELsHQLLQDRAKGAQAsPPPIAPyPsPTRKDLLLHMQ |
| Q14164 | S673 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | LLQDRAKGAQAsPPPIAPyPsPTRKDLLLHMQELCEGMKLL |
| Q14164 | S695 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | TRKDLLLHMQELCEGMKLLAsDLLDNNRIIERLNRVPAPPD |
| Q14164 | T156 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | IKPGNIMRLVGEEGQsIyKLtDFGAARELDDDEKFVsVyGt |
| Q14164 | T176 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | tDFGAARELDDDEKFVsVyGtEEyLHPDMYERAVLRKPQQK |
| Q14164 | T414 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | DPALDVPKFVPKVDLQADYNtAKGVLGAGYQALRLARALLD |
| Q14164 | T483 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | TSLLYLSSSLGTERFSsVAGtPEIQELKAAAELRSRLRtLA |
| Q14164 | T501 | SIGNOR|PSP | IKBKE IKKE IKKI KIAA0151 | AGtPEIQELKAAAELRSRLRtLAEVLSRCSQNITETQEsLS |
| Q14164 | Y153 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | HRDIKPGNIMRLVGEEGQsIyKLtDFGAARELDDDEKFVsV |
| Q14164 | Y174 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | KLtDFGAARELDDDEKFVsVyGtEEyLHPDMYERAVLRKPQ |
| Q14164 | Y671 | Sugiyama | IKBKE IKKE IKKI KIAA0151 | HQLLQDRAKGAQAsPPPIAPyPsPTRKDLLLHMQELCEGMK |
| Q14192 | S238 | Sugiyama | FHL2 DRAL SLIM3 | AKKCAGCTNPISGLGGtKyIsFEERQWHNDCFNCKKCsLsL |
| Q14192 | S257 | Sugiyama | FHL2 DRAL SLIM3 | IsFEERQWHNDCFNCKKCsLsLVGRGFLTERDDILCPDCGK |
| Q14203 | S320 | Sugiyama | DCTN1 | TADAIEMATLDKEMAEERAEsLQQEVEALKERVDELTTDLE |
| Q14247 | S331 | Sugiyama | CTTN EMS1 | GVQKDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKtsNIR |
| Q14247 | S432 | Sugiyama | CTTN EMS1 | EERLPssPVyEDAAsFKAELsyRGPVsGtEPEPVysMEAAD |
| Q14247 | S447 | Sugiyama | CTTN EMS1 | FKAELsyRGPVsGtEPEPVysMEAADyREASSQQGLAYATE |
| Q14257 | S207 | Sugiyama | RCN2 ERC55 | TEFVIQEALEEHDKNGDGFVsLEEFLGDyRWDPTANEDPEW |
| Q14444 | S200 | Sugiyama | CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 | EEELSLLDEFyKLVDPERDMsLRLNEQYEHASIHLWDLLEG |
| Q14444 | S307 | Sugiyama | CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 | SEVESTEYVNRQFMAEtQFtsGEKEQVDEWTVETVEVVNSL |
| Q14568 | S50 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL |
| Q14653 | S385 | SIGNOR | IRF3 | VKVVPTCLRALVEMARVGGAssLENtVDLHIsNsHPLsLts |
| Q14653 | S386 | GPS6|SIGNOR|ELM|EPSD|PSP | IRF3 | KVVPTCLRALVEMARVGGAssLENtVDLHIsNsHPLsLtsD |
| Q14653 | S396 | SIGNOR|EPSD|PSP | IRF3 | VEMARVGGAssLENtVDLHIsNsHPLsLtsDQYKAYLQDLV |
| Q14653 | S398 | SIGNOR|EPSD|PSP | IRF3 | MARVGGAssLENtVDLHIsNsHPLsLtsDQYKAYLQDLVEG |
| Q14653 | S402 | SIGNOR|EPSD|PSP | IRF3 | GGAssLENtVDLHIsNsHPLsLtsDQYKAYLQDLVEGMDFQ |
| Q14653 | S405 | SIGNOR | IRF3 | ssLENtVDLHIsNsHPLsLtsDQYKAYLQDLVEGMDFQGPG |
| Q14653 | T404 | SIGNOR | IRF3 | AssLENtVDLHIsNsHPLsLtsDQYKAYLQDLVEGMDFQGP |
| Q14671 | S183 | Sugiyama | PUM1 KIAA0099 PUMH1 | PKGIFLGDQWRDsAWGTsDHsVsQPIMVQRRPGQsFHVNsE |
| Q14677 | S164 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | RLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKW |
| Q14677 | S166 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE |
| Q14684 | S422 | Sugiyama | RRP1B KIAA0179 | KKKKKHHLQPENPGPGGAAPsLEQNRGREPEASGLKALKAR |
| Q14697 | S916 | Sugiyama | GANAB G2AN KIAA0088 | GAGKPAAVVLQTKGSPEsRLsFQHDPEtsVLVLRKPGINVA |
| Q14847 | S99 | Sugiyama | LASP1 MLN50 | ELQsQVRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsN |
| Q14974 | S531 | Sugiyama | KPNB1 NTF97 | LETTDRPDGHQNNLRSSAyEsLMEIVKNSAKDCYPAVQKTT |
| Q14980 | S1789 | Sugiyama | NUMA1 NMP22 NUMA | sLEsLyFtPIPARsQAPLEssLDsLGDVFLDsGRKtRSARR |
| Q14980 | S1792 | Sugiyama | NUMA1 NMP22 NUMA | sLyFtPIPARsQAPLEssLDsLGDVFLDsGRKtRSARRRtt |
| Q14C86 | S740 | Sugiyama | GAPVD1 GAPEX5 KIAA1521 RAP6 | LPSDSEAPDLKQEERLQELEsCsGLGstSDDTDVREVSSRP |
| Q14C86 | S742 | Sugiyama | GAPVD1 GAPEX5 KIAA1521 RAP6 | SDSEAPDLKQEERLQELEsCsGLGstSDDTDVREVSSRPST |
| Q14CN4 | S138 | Sugiyama | KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 | IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN |
| Q15056 | S110 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK |
| Q15056 | S94 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | RDKDTDKFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVD |
| Q15056 | T100 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | KFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRK |
| Q15056 | Y101 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | FKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRKQ |
| Q15084 | S169 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | GKQGRSDsSSKKDVIELtDDsFDKNVLDSEDVWMVEFYAPW |
| Q15084 | S88 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | AATALKDVVKVGAVDADKHHsLGGQyGVQGFPtIKIFGSNK |
| Q15084 | T100 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | AVDADKHHsLGGQyGVQGFPtIKIFGSNKNRPEDYQGGRTG |
| Q15084 | Y93 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | KDVVKVGAVDADKHHsLGGQyGVQGFPtIKIFGSNKNRPED |
| Q15185 | S118 | Sugiyama | PTGES3 P23 TEBP | WLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGDEDVDL |
| Q15185 | S72 | Sugiyama | PTGES3 P23 TEBP | EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE |
| Q15393 | S1184 | Sugiyama | SF3B3 KIAA0017 SAP130 | RSyyFPVKNVIDGDLCEQFNsMEPNKQKNVSEELDRtPPEV |
| Q15398 | S777 | Sugiyama | DLGAP5 DLG7 KIAA0008 | sItSQDVLMssPEKNTAsQNsILEEGEtKIsQsELFDNKsL |
| Q15459 | S506 | Sugiyama | SF3A1 SAP114 | KKIGEEEIQKPEEKVTWDGHsGsMARTQQAAQANITLQEQI |
| Q15459 | S690 | Sugiyama | SF3A1 SAP114 | VHPPPPMEDEPTSKKLKTEDsLMPEEEFLRRNKGPVSIKVQ |
| Q15642 | S299 | Sugiyama | TRIP10 CIP4 STOT STP | PGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRTK |
| Q15643 | S406 | Sugiyama | TRIP11 CEV14 | EVFRLQQALSDAENEIMRLSsLNQDNsLAEDNLKLKMRIEV |
| Q15814 | S23 | Sugiyama | TBCC | SVSCSAAAVRTGDMESQRDLsLVPERLQRREQERQLEVERR |
| Q16513 | S583 | Sugiyama | PKN2 PRK2 PRKCL2 | VTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQDs |
| Q16576 | S146 | Sugiyama | RBBP7 RBAP46 | VNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGEC |
| Q16719 | S443 | Sugiyama | KYNU | VVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAET |
| Q16719 | S460 | Sugiyama | KYNU | LyNsFHDVyKFTNLLtsILDsAETKN_______________ |
| Q16719 | T455 | Sugiyama | KYNU | VAPVPLyNsFHDVyKFTNLLtsILDsAETKN__________ |
| Q2TAA2 | S241 | Sugiyama | IAH1 | SSLPLLLPYWRDVAEAKPELsLLGDGDH_____________ |
| Q32MZ4 | S766 | Sugiyama | LRRFIP1 GCF2 TRIP | sTERCEMSEHPSQTVRKALDsNsLENDDLSAPGREPGHFNP |
| Q3SY84 | S143 | Sugiyama | KRT71 K6IRS1 KB34 KRT6IRS1 | IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q3ZCM7 | S75 | Sugiyama | TUBB8 | SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC |
| Q4G0X9 | S553 | Sugiyama | CCDC40 KIAA1640 | EIEAYKKSIMKEEEKNEKLAsILNRTETEATLLQKLTTQCL |
| Q4V328 | S291 | Sugiyama | GRIPAP1 KIAA1167 | HKAQLARTQKLQQELEAANQsLAELRDQRQGERLEHAAALR |
| Q53EL6 | S49 | Sugiyama | PDCD4 H731 | ENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKNssR |
| Q562R1 | T250 | Sugiyama | ACTBL2 | RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI |
| Q58FF6 | S34 | Sugiyama | HSP90AB4P | IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN |
| Q58FF7 | S185 | Sugiyama | HSP90AB3P HSP90BC | KEDQtEyLEERRVKEVVKKHsQFIGyPItLyLEKEQDKEIs |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF7 | S58 | Sugiyama | HSP90AB3P HSP90BC | IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| Q58FF7 | T193 | Sugiyama | HSP90AB3P HSP90BC | EERRVKEVVKKHsQFIGyPItLyLEKEQDKEIsDDEAEEEK |
| Q58FF8 | S258 | Sugiyama | HSP90AB2P HSP90BB | LAVRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQ |
| Q58FF8 | S58 | Sugiyama | HSP90AB2P HSP90BB | IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| Q5H9R7 | S579 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | IDQFGFNDEKFADQDDIGNVsFDRVSDINFTLNTNESGNIA |
| Q5H9R7 | S868 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | RPPsssPEQRTGQPSAPGDtsVNGPV_______________ |
| Q5T035 | T62 | Sugiyama | FAM120A2P C9orf129 | yPysLSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyER |
| Q5XKE5 | S155 | Sugiyama | KRT79 K6L KB38 KRT6L | IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| Q66LE6 | S418 | Sugiyama | PPP2R2D KIAA1541 | LKPRKVCTGGKRRKDEIsVDsLDFNKKILHTAWHPVDNVIA |
| Q6FI81 | S305 | Sugiyama | CIAPIN1 CUA001 PRO0915 | CAsCPyLGMPAFKPGEKVLLsDsNLHDA_____________ |
| Q6P996 | S786 | Sugiyama | PDXDC1 KIAA0251 | AFQKGVPHPEDDHsQVEGPEsLR__________________ |
| Q6PEY2 | S48 | Sugiyama | TUBA3E | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q6PEY2 | S54 | Sugiyama | TUBA3E | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q6PEY2 | T41 | Sugiyama | TUBA3E | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q6PEY2 | T51 | Sugiyama | TUBA3E | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | T949 | Sugiyama | POTEE A26C1A POTE2 | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q6UXH1 | S295 | Sugiyama | CRELD2 UNQ185/PRO211 | KECISGYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSY |
| Q71U36 | S439 | Sugiyama | TUBA1A TUBA3 | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| Q71U36 | S48 | Sugiyama | TUBA1A TUBA3 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q71U36 | S54 | Sugiyama | TUBA1A TUBA3 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q71U36 | T41 | Sugiyama | TUBA1A TUBA3 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q71U36 | T51 | Sugiyama | TUBA1A TUBA3 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T80 | Sugiyama | TUBA1A TUBA3 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q71U36 | Y83 | Sugiyama | TUBA1A TUBA3 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q71UM5 | S11 | Sugiyama | RPS27L | __________MPLARDLLHPsLEEEKKKHKKKRLVQsPNsy |
| Q7KZF4 | S126 | Sugiyama | SND1 TDRD11 | GREyGMIyLGKDTNGENIAEsLVAEGLAtRREGMRANNPEQ |
| Q7RTS7 | S153 | Sugiyama | KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 | IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE |
| Q7RTV0 | S53 | Sugiyama | PHF5A | CDSyVRPCTLVRICDECNyGsyQGRCVICGGPGVSDAyyCK |
| Q7Z2W4 | S492 | Sugiyama | ZC3HAV1 ZC3HDC2 PRO1677 | VQATGRIADDADPRVALVNDsLsDVtsTtssRVDDHDSEEI |
| Q7Z2W4 | S494 | Sugiyama | ZC3HAV1 ZC3HDC2 PRO1677 | ATGRIADDADPRVALVNDsLsDVtsTtssRVDDHDSEEICL |
| Q7Z3K3 | S28 | Sugiyama | POGZ KIAA0461 SUHW5 ZNF280E ZNF635 Nbla00003 | MECEEEELEPWQKISDVIEDsVVEDyNsVDKTTTVSVSQQP |
| Q7Z417 | S592 | Sugiyama | NUFIP2 KIAA1321 PIG1 | sPQVLGSILKsGttsEsGALsLEPsHIGDLQKADtssQGAL |
| Q7Z417 | S596 | Sugiyama | NUFIP2 KIAA1321 PIG1 | LGSILKsGttsEsGALsLEPsHIGDLQKADtssQGALVFLS |
| Q7Z417 | S652 | Sugiyama | NUFIP2 KIAA1321 PIG1 | NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI |
| Q7Z417 | S655 | Sugiyama | NUFIP2 KIAA1321 PIG1 | LGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsIWNL |
| Q7Z4S6 | S708 | Sugiyama | KIF21A KIAA1708 KIF2 | KIRDTQLERDQVLQNLGsVEsysEEKAKKVRSEYEKKLQAM |
| Q7Z4S6 | Y709 | Sugiyama | KIF21A KIAA1708 KIF2 | IRDTQLERDQVLQNLGsVEsysEEKAKKVRSEYEKKLQAMN |
| Q7Z794 | S177 | Sugiyama | KRT77 KRT1B | IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| Q86UE4 | S306 | Sugiyama | MTDH AEG1 LYRIC | WNEKSVKLssQIsAGEEKWNsVsPAsAGKRKtEPSAWsQDt |
| Q86UP2 | S906 | Sugiyama | KTN1 CG1 KIAA0004 | KEKDLANTGKWLQDLQEENEsLKAHVQEVAQHNLKEASSAS |
| Q86V81 | S145 | Sugiyama | ALYREF ALY BEF THOC4 | LFAEFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQ |
| Q86V81 | S8 | Sugiyama | ALYREF ALY BEF THOC4 | _____________MADKMDMsLDDIIKLNRSQRGGRGGGRG |
| Q86Y46 | S145 | Sugiyama | KRT73 K6IRS3 KB36 KRT6IRS3 | IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q8IW35 | S500 | Sugiyama | CEP97 LRRIQ2 | GLLPCPEPTIISAILKDDNHsLtFFPESTEQKQSDIKKPEN |
| Q8IWZ3 | S803 | Sugiyama | ANKHD1 KIAA1085 MASK VBARP PP2500 | EGKLNELGQRISAIEKAQLKsLELIQGEPLNKDKIEELKKN |
| Q8N0Y7 | S134 | Sugiyama | PGAM4 PGAM3 | IWRRsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSYE |
| Q8N6H7 | S364 | Sugiyama | ARFGAP2 ZNF289 Nbla10535 | LFDDVGTFASGPPKYKDNPFsLGEsFGsRWDTDAAWGMDRV |
| Q8N6T3 | S174 | Sugiyama | ARFGAP1 ARF1GAP | QsVtAssDKAFEDWLNDDLGsyQGAQGNRyVGFGNtPPPQK |
| Q8N6T3 | S348 | Sugiyama | ARFGAP1 ARF1GAP | FWETFGSAEPTKtRKsPssDsWtCADtstERRssDsWEVWG |
| Q8NBJ7 | S256 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG |
| Q8NBS9 | S285 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | LLWFRDGKKVDQYKGKRDLEsLREyVEsQLQRTETGATETV |
| Q8ND56 | S300 | Sugiyama | LSM14A C19orf13 FAM61A RAP55 RAP55A | GRFGIRRDGPMKFEKDFDFEsANAQFNKEEIDREFHNKLKL |
| Q8NFI4 | S181 | Sugiyama | ST13P5 FAM10A5 | LQKPNAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| Q8TAM6 | S280 | Sugiyama | ERMN KIAA1189 | TISYRKIRKGNTKQRIDEFEsMMHL________________ |
| Q8TD19 | S13 | Sugiyama | NEK9 KIAA1995 NEK8 NERCC | ________MsVLGEYERHCDsINSDFGSEsGGCGDssPGPS |
| Q8WU90 | S231 | Sugiyama | ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 | LPPGFVLKKDKKKEEKEDEIsLEDLIERERSALGPNVTKIT |
| Q8WU90 | S351 | Sugiyama | ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 | DIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLsEAs |
| Q8WUD4 | S149 | Sugiyama | CCDC12 | KRTQRAIAELIRERLKGQEDsLAsAVDAATEQKtCDsD___ |
| Q8WVJ2 | S142 | Sugiyama | NUDCD2 | LTLERFQKENPGFDFsGAEIsGNytKGGPDFsNLEK_____ |
| Q8WVJ2 | S153 | Sugiyama | NUDCD2 | GFDFsGAEIsGNytKGGPDFsNLEK________________ |
| Q8WWI1 | S704 | Sugiyama | LMO7 FBX20 FBXO20 KIAA0858 | KKRLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEM |
| Q8WWM7 | S563 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | EELRKFGAQFKLQPsssPENsLDPFPPRILKEEPKGKEKEV |
| Q8WXX5 | S215 | Sugiyama | DNAJC9 | EEAKEAEMSRKELGLDEGVDsLKAAIQSRQKDRQKEMDNFL |
| Q92688 | S117 | Sugiyama | ANP32B APRIL PHAPI2 | GNKLKDIstLEPLKKLECLKsLDLFNCEVtNLNDyREsVFK |
| Q92734 | S183 | Sugiyama | TFG | AsMsAFDPLKNQDEINKNVMsAFGLtDDQVsGPPsAPAEDR |
| Q92734 | S197 | Sugiyama | TFG | INKNVMsAFGLtDDQVsGPPsAPAEDRSGTPDSIASSSSAA |
| Q92785 | S142 | Sugiyama | DPF2 BAF45D REQ UBID4 | LLRTDPLEKRGAPDPRVDDDsLGEFPVTNsRARKRILEPDD |
| Q92844 | S100 | SIGNOR | TANK ITRAF TRAF2 | EDSETRKNNLTLDQPQDKVIsGIAREKLPKVRRQEVSsPRK |
| Q92844 | S126 | SIGNOR | TANK ITRAF TRAF2 | KLPKVRRQEVSsPRKETSARsLGsPLLHERGNIEKTFWDLK |
| Q92844 | S178 | SIGNOR | TANK ITRAF TRAF2 | AQKDHLSKLNIPDTATEtQCsVPIQCTDKTDKQEALFKPQA |
| Q92844 | S208 | SIGNOR | TANK ITRAF TRAF2 | DKQEALFKPQAKDDINRGAPsITsVtPRGLCRDEEDtsFEs |
| Q92844 | S228 | SIGNOR | TANK ITRAF TRAF2 | sITsVtPRGLCRDEEDtsFEsLsKFNVKFPPMDNDSTFLHS |
| Q92844 | S257 | SIGNOR | TANK ITRAF TRAF2 | PPMDNDSTFLHStPERPGILsPAtSEAVCQEKFNMEFRDNP |
| Q92844 | S406 | SIGNOR | TANK ITRAF TRAF2 | TDSELHIPRVCEFCQAVFPPsITsRGDFLRHLNSHFNGET_ |
| Q92844 | S409 | SIGNOR | TANK ITRAF TRAF2 | ELHIPRVCEFCQAVFPPsITsRGDFLRHLNSHFNGET____ |
| Q92844 | S49 | SIGNOR | TANK ITRAF TRAF2 | ELQQKTENYEQRIREQQEQLsLQQTIIDKLKSQLLLVNstQ |
| Q92890 | S299 | Sugiyama | UFD1 UFD1L | KKVEEDEAGGRFVAFsGEGQsLRKKGRKP____________ |
| Q92985 | S471 | SIGNOR|EPSD|PSP | IRF7 | VKLEPWLCRVHLEGTQREGVssLDSSsLsLCLsSANsLYDD |
| Q92985 | S472 | SIGNOR|EPSD|PSP | IRF7 | KLEPWLCRVHLEGTQREGVssLDSSsLsLCLsSANsLYDDI |
| Q92985 | S477 | GPS6|EPSD|PSP | IRF7 | LCRVHLEGTQREGVssLDSSsLsLCLsSANsLYDDIECFLM |
| Q92985 | S479 | GPS6|EPSD|PSP | IRF7 | RVHLEGTQREGVssLDSSsLsLCLsSANsLYDDIECFLMEL |
| Q93045 | S80 | Sugiyama | STMN2 SCG10 SCGN10 | PPsPISEAPRTLAsPKKKDLsLEEIQKKLEAAEERRKsQEA |
| Q96AC1 | S159 | PSP | FERMT2 KIND2 MIG2 PLEKHC1 | SLLKKPRDPTKKKKKKLDDQsEDEALELEGPLItPGsGsIy |
| Q96AE4 | S52 | Sugiyama | FUBP1 | KDALQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQ |
| Q96AQ6 | S147 | SIGNOR|PSP | PBXIP1 HPIP | PQSLPSTPKAAWIREEGRCsssDDDTDVDMEGLRRRRGREA |
| Q96B36 | S211 | Sugiyama | AKT1S1 PRAS40 | WGFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAE |
| Q96C01 | S135 | Sugiyama | FAM136A | VDDHMHLIPTMTKKMKEALLsIGK_________________ |
| Q96CT7 | S122 | Sugiyama | CCDC124 | DtLRRDHQLREAPDTAEKAKsHLEVPLEENVNRRVLEEGsV |
| Q96FA3 | S293 | EPSD|PSP | PELI1 PRISM | QEINAARPQCPVGFNtLAFPsMKRKDVVDEKQPWVYLNCGH |
| Q96FA3 | S76 | EPSD|PSP | PELI1 PRISM | TVHIACTPQAAKAIsNKDQHsIsYtLsRAQtVVVEYTHDSN |
| Q96FA3 | T288 | EPSD|PSP | PELI1 PRISM | LEALRQEINAARPQCPVGFNtLAFPsMKRKDVVDEKQPWVY |
| Q96FA3 | T80 | EPSD|PSP | PELI1 PRISM | ACTPQAAKAIsNKDQHsIsYtLsRAQtVVVEYTHDSNTDMF |
| Q96HE7 | S143 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD |
| Q96MH2 | S194 | Sugiyama | HEXIM2 L3 | EAGDSDGRGRAHGEFQRKDFsEtYERFHTESLQGRSKQELV |
| Q96MH2 | T196 | Sugiyama | HEXIM2 L3 | GDSDGRGRAHGEFQRKDFsEtYERFHTESLQGRSKQELVRD |
| Q99497 | S57 | Sugiyama | PARK7 | GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL |
| Q99584 | S62 | Sugiyama | S100A13 | VTQQLPHLLKDVGSLDEKMKsLDVNQDSELKFNEyWRLIGE |
| Q99613 | S865 | Sugiyama | EIF3C EIF3S8 | HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF |
| Q99614 | S275 | Sugiyama | TTC1 TPR1 | GNLVLRPFGLstENFQIKQDsstGsysINFVQNPNNNR___ |
| Q99614 | S281 | Sugiyama | TTC1 TPR1 | PFGLstENFQIKQDsstGsysINFVQNPNNNR_________ |
| Q99733 | Y55 | Sugiyama | NAP1L4 NAP2 | PRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQV |
| Q9BQE3 | S48 | Sugiyama | TUBA1C TUBA6 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q9BQE3 | S54 | Sugiyama | TUBA1C TUBA6 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q9BQE3 | T41 | Sugiyama | TUBA1C TUBA6 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q9BQE3 | T51 | Sugiyama | TUBA1C TUBA6 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T80 | Sugiyama | TUBA1C TUBA6 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q9BQE3 | Y83 | Sugiyama | TUBA1C TUBA6 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q9BR76 | S391 | Sugiyama | CORO1B | EAALEAEEWVSGRDADPILIsLREAYVPSKQRDLKISRRNV |
| Q9BRA2 | S41 | Sugiyama | TXNDC17 TXNL5 | QHNGKTIFAyFTGSKDAGGKsWCPDCVQAEPVVREGLKHIS |
| Q9BRK5 | S158 | Sugiyama | SDF4 CAB45 PSEC0034 | AMEEsKTHFRAVDPDGDGHVsWDEyKVKFLASKGHSEKEVA |
| Q9BRS2 | S130 | Sugiyama | RIOK1 RIO1 | DKVLRKFENKINLDKLNVtDsVINKVTEKSRQKEADMYRIK |
| Q9BTD8 | S372 | Sugiyama | RBM42 | KPEKLKRCIRtAAGSSWEDPsLLEWDADDFRIFCGDLGNEV |
| Q9BVA1 | S115 | Sugiyama | TUBB2B | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q9BVA1 | S75 | Sugiyama | TUBB2B | tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q9BVS4 | S412 | Sugiyama | RIOK2 RIO2 | EMTEFNQALEEIKGQVVENNsVTEFsEEKNRTENYNRQDGQ |
| Q9BW91 | S238 | Sugiyama | NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771 | DPGEKISATLKREFGEEALNsLQKTSAEKREIEEKLHKLFS |
| Q9BX40 | S349 | Sugiyama | LSM14B C20orf40 FAM61B RAP55B | SSRRTTWAEERKLNtEtFGVsGRFLRGRSSRGGFRGGRGNG |
| Q9BXS6 | S363 | Sugiyama | NUSAP1 ANKT BM-037 PRO0310 | TtEAtQtPVsNKKPVFDLKAsLsRPLNyEPHKGKLKPWGQS |
| Q9BY32 | S53 | Sugiyama | ITPA C20orf37 My049 OK/SW-cl.9 | CTLVAQKIDLPEyQGEPDEIsIQKCQEAVRQVQGPVLVEDT |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BYX7 | T249 | Sugiyama | POTEKP ACTBL3 FKSG30 | MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q9C005 | S50 | Sugiyama | DPY30 | IVENEKINAEKSSKQKVDLQsLPTRAYLDQTVVPILLQGLA |
| Q9C0C2 | S1047 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | LFsPstAHVPDGALGQRDQssWQNsDAsQEVGGHQERQQAG |
| Q9C0C2 | S1229 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | LESGGSEEPGGIGVGEKDWtsDVNVKSKDLAEVGEGGGHsQ |
| Q9C0C2 | S882 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | LQDQEFGKRDsLGtyssRDVsLGDWEFGKRDsLGAyAsQDA |
| Q9C0C2 | S936 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | GRyssQDADEQDWEFQKRDVsLGTyGSRAAEPQEQEFGKSA |
| Q9GZT3 | S15 | Sugiyama | SLIRP C14orf156 DC23 DC50 PD04872 | ______MAASAARGAAALRRsINQPVAFVRRIPWTAASSQL |
| Q9GZZ9 | S24 | Sugiyama | UBA5 UBE1DC1 | SVERLQQRVQELERELAQERsLQVPRSGDGGGGRVRIEKMs |
| Q9H0A0 | S984 | Sugiyama | NAT10 ALP KIAA1709 | IIRGDDEEWNEVLNKAGPNAsIIsLKsDKKRKLEAKQEPKQ |
| Q9H0A0 | S987 | Sugiyama | NAT10 ALP KIAA1709 | GDDEEWNEVLNKAGPNAsIIsLKsDKKRKLEAKQEPKQSKK |
| Q9H0L4 | S344 | Sugiyama | CSTF2T KIAA0689 | LPPRGLLGDAPNDPRGGtLLsVtGEVEPRGYLGPPHQGPPM |
| Q9H2G2 | S344 | Sugiyama | SLK KIAA0204 STK2 | EEEtENsLPIPAsKRAssDLsIAssEEDKLsQNACILEsVS |
| Q9H2U2 | S309 | Sugiyama | PPA2 HSPC124 | NCTNVQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVW |
| Q9H2U2 | S313 | Sugiyama | PPA2 HSPC124 | VQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLG |
| Q9H3P7 | S316 | Sugiyama | ACBD3 GCP60 GOCAP1 GOLPH1 | QLAQQQAALQKQQEVVVAGssLPtssKVNATVPSNMMSVNG |
| Q9H3P7 | S393 | Sugiyama | ACBD3 GCP60 GOCAP1 GOLPH1 | SMWTRPQIKDFKEKIQQDADsVItVGRGEVVTVRVPTHEEG |
| Q9H3Q1 | S309 | Sugiyama | CDC42EP4 BORG4 CEP4 | AAPsPGsARSMGSHTTRDSSsLssCtsGILEERsPAFRGPD |
| Q9H6T3 | S507 | Sugiyama | RPAP3 | PTsDtPRAKVLKIEEVsDTssLQPQAsLKQDVCQsYsEKMP |
| Q9H765 | S17 | PSP | ASB8 PP14212 | ____MSSSMWYIMQSIQSKYsLSERLIRTIAAIRsFPHDNV |
| Q9H788 | S124 | Sugiyama | SH2D4A PPP1R38 SH2A | LKAEQEAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKD |
| Q9NPQ8 | S452 | Sugiyama | RIC8A | EGQysEDEDtDtDEyKEAKAsINPVTGRVEEKPPNPMEGMT |
| Q9NQX3 | S262 | Sugiyama | GPHN GPH KIAA1385 | AKIPDSIISRGVQVLPRDTAsLsttPsEsPRAQAtsRLstA |
| Q9NSB2 | S178 | Sugiyama | KRT84 KRTHB4 | AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS |
| Q9NVS9 | S55 | Sugiyama | PNPO | GPMRKsYRGDREAFEETHLTsLDPVKQFAAWFEEAVQCPDI |
| Q9NZB2 | T413 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | yPysLSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyER |
| Q9NZL9 | S9 | Sugiyama | MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 | ____________MVGREKELsIHFVPGsCRLVEEEVNIPNR |
| Q9UBC2 | S518 | Sugiyama | EPS15L1 EPS15R | LNRAKSELNRLQQEETQLEQsIQAGRVQLETIIKSLKSTQD |
| Q9UBR2 | S78 | Sugiyama | CTSZ | SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST |
| Q9UHB6 | S704 | Sugiyama | LIMA1 EPLIN SREBP3 PP624 | ADsDEDDNsFLKQQsPQEPKsLNWssFVDNtFAEEFTTQNQ |
| Q9UHB6 | S708 | Sugiyama | LIMA1 EPLIN SREBP3 PP624 | EDDNsFLKQQsPQEPKsLNWssFVDNtFAEEFTTQNQKsQD |
| Q9UII2 | S39 | Sugiyama | ATP5IF1 ATPI ATPIF1 | TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF |
| Q9UKK9 | S24 | Sugiyama | NUDT5 NUDIX5 HSPC115 | QEPtEssQNGKQyIISEELIsEGKWVKLEKTTYMDPTGKtR |
| Q9UKS6 | S327 | Sugiyama | PACSIN3 | QRtIsRKEKGGRsPDEVtLtsIVPTRDGTAPPPQsPGsPGt |
| Q9ULV4 | S389 | Sugiyama | CORO1C CRN2 CRNN4 | EAALEAEEWFEGKNADPILIsLKHGYIPGKNRDLKVVKKNI |
| Q9UNN5 | S556 | SIGNOR|PSP | FAF1 UBXD12 UBXN3A CGI-03 | QFRLEQIRKEQEEEREAIRLsLEQALPPEPKEENAEPVSKL |
| Q9UPN9 | S856 | Sugiyama | TRIM33 KIAA1113 RFG7 TIF1G | NHVKIEPADMNESCKQsGLssLVNGKsPIRSLMHRSARIGG |
| Q9UPQ0 | S204 | Sugiyama | LIMCH1 KIAA1102 | DsERsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVVLRG |
| Q9UPQ0 | S207 | Sugiyama | LIMCH1 KIAA1102 | RsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVVLRGssD |
| Q9UPQ0 | S585 | Sugiyama | LIMCH1 KIAA1102 | ETVHREEEKERECPTVAPAHsLtKSQMFEGVARVHGsPLEL |
| Q9UQ35 | S1150 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | GMsPEQsRFQsDsssyPtVDsNsLLGQsRLETAESKEKMAL |
| Q9UQ35 | S1152 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sPEQsRFQsDsssyPtVDsNsLLGQsRLETAESKEKMALPP |
| Q9UQ35 | S1318 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | VPsMASSWGGPHFsPEHKELsNsPLRENsFGsPLEFRNsGP |
| Q9UQ35 | S1326 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | GGPHFsPEHKELsNsPLRENsFGsPLEFRNsGPLGTEMNtG |
| Q9UQ80 | T386 | Sugiyama | PA2G4 EBP1 | tQKKKKKKAsKtAENAtsGEtLEENEAGD____________ |
| Q9Y266 | S136 | Sugiyama | NUDC | QLEIDQKKDAENHEAQLKNGsLDsPGKQDtEEDEEEDEKDK |
| Q9Y266 | S285 | Sugiyama | NUDC | NtKKINPENsKLsDLDsEtRsMVEKMMYDQRQKsMGLPtsD |
| Q9Y2B0 | S139 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | DLQGIRIDsDISGtLKFACEsIVEEyEDELIEFFsREADNV |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2L5 | S279 | Sugiyama | TRAPPC8 KIAA1012 | sYEDGPCtItsNKNsDNNLLsLDGLDNEVKDGLPNNFRAHP |
| Q9Y3F4 | S230 | Sugiyama | STRAP MAWD UNRIP | SAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLyKy |
| Q9Y450 | S67 | Sugiyama | HBS1L HBS1 KIAA1038 | KPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCLDH |
| Q9Y4L1 | S461 | Sugiyama | HYOU1 GRP170 HSPH4 ORP150 | VVYPILVEFTREVEEEPGIHsLKHNKRVLFSRMGPYPQRKV |
| Q9Y4X5 | S517 | Sugiyama | ARIH1 ARI MOP6 UBCH7BP HUSSY-27 | DLENATEVLSGYLERDIsQDsLQDIKQKVQDKYRYCESRRR |
| Q9Y5L4 | S57 | Sugiyama | TIMM13 TIM13B TIMM13A TIMM13B | ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW |
| Q9Y5S9 | S56 | Sugiyama | RBM8A RBM8 HSPC114 MDS014 | KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF |
| Q9Y5X1 | S116 | Sugiyama | SNX9 SH3PX1 SH3PXD3A | SNNHQVGSGNDPWSAWSASKsGNWESsEGWGAQPEGAGAQR |
| Q9Y696 | S31 | Sugiyama | CLIC4 | KEEDKEPLIELFVKAGsDGEsIGNCPFSQRLFMILWLKGVV |
| Q9Y6G9 | S381 | Sugiyama | DYNC1LI1 DNCLI1 | FVHEKEIMAEDDQVFLMKLQsLLAKQPPtAAGRPVDAsPRV |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle | R-HSA-1640170 | 2.542411e-14 | 13.595 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.718625e-12 | 11.765 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.462395e-10 | 9.835 | 1 | 0 |
| M Phase | R-HSA-68886 | 7.138670e-10 | 9.146 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 9.447573e-10 | 9.025 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 5.722630e-09 | 8.242 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 2.342471e-08 | 7.630 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 7.453467e-08 | 7.128 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 8.570762e-08 | 7.067 | 1 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 9.993841e-08 | 7.000 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 1.319798e-07 | 6.879 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.782481e-07 | 6.749 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 4.855667e-07 | 6.314 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 8.924795e-07 | 6.049 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.270605e-06 | 5.896 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.754781e-06 | 5.756 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.940571e-06 | 5.712 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 3.159511e-06 | 5.500 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 4.412854e-06 | 5.355 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 5.090515e-06 | 5.293 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 5.090515e-06 | 5.293 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 7.474003e-06 | 5.126 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 7.816169e-06 | 5.107 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 9.719017e-06 | 5.012 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 1.068635e-05 | 4.971 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.064241e-05 | 4.973 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.190715e-05 | 4.924 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.217273e-05 | 4.915 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.326168e-05 | 4.877 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.326168e-05 | 4.877 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.607284e-05 | 4.794 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.751016e-05 | 4.757 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.092218e-05 | 4.679 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.092218e-05 | 4.679 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 2.323256e-05 | 4.634 | 1 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.541301e-05 | 4.595 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 3.907132e-05 | 4.408 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 4.187182e-05 | 4.378 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.263490e-05 | 4.370 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 5.236814e-05 | 4.281 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 5.684782e-05 | 4.245 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 6.002470e-05 | 4.222 | 1 | 1 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 6.192564e-05 | 4.208 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 6.310553e-05 | 4.200 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 8.201848e-05 | 4.086 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 8.041221e-05 | 4.095 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 8.664790e-05 | 4.062 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.000610e-04 | 4.000 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.001723e-04 | 3.999 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.035884e-04 | 3.985 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 1.073405e-04 | 3.969 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 1.201370e-04 | 3.920 | 1 | 1 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 1.211667e-04 | 3.917 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.368051e-04 | 3.864 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.544374e-04 | 3.811 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.544374e-04 | 3.811 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 1.680588e-04 | 3.775 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 1.857836e-04 | 3.731 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.987079e-04 | 3.702 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.939906e-04 | 3.712 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 1.987079e-04 | 3.702 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 2.002983e-04 | 3.698 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 2.211834e-04 | 3.655 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.283235e-04 | 3.641 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 2.384205e-04 | 3.623 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 2.609956e-04 | 3.583 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 2.609956e-04 | 3.583 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.651309e-04 | 3.577 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 3.956620e-04 | 3.403 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 3.976287e-04 | 3.401 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 4.133731e-04 | 3.384 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 4.140140e-04 | 3.383 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 4.370050e-04 | 3.360 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 4.904837e-04 | 3.309 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 4.863344e-04 | 3.313 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 5.576568e-04 | 3.254 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 5.884861e-04 | 3.230 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 6.768108e-04 | 3.170 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 6.836691e-04 | 3.165 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 7.040796e-04 | 3.152 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 7.358602e-04 | 3.133 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 8.125375e-04 | 3.090 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 8.130925e-04 | 3.090 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 8.130925e-04 | 3.090 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 9.093530e-04 | 3.041 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 8.803833e-04 | 3.055 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 9.093530e-04 | 3.041 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 9.744759e-04 | 3.011 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 1.119559e-03 | 2.951 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.229287e-03 | 2.910 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.282989e-03 | 2.892 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.361605e-03 | 2.866 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.335537e-03 | 2.874 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.335537e-03 | 2.874 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.335537e-03 | 2.874 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.335537e-03 | 2.874 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.372613e-03 | 2.862 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.390607e-03 | 2.857 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 1.361605e-03 | 2.866 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.616864e-03 | 2.791 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.616864e-03 | 2.791 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.616864e-03 | 2.791 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.616864e-03 | 2.791 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.616864e-03 | 2.791 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.616864e-03 | 2.791 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.616864e-03 | 2.791 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.616864e-03 | 2.791 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.616864e-03 | 2.791 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.616864e-03 | 2.791 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.616864e-03 | 2.791 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.606722e-03 | 2.794 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 1.688241e-03 | 2.773 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.702512e-03 | 2.769 | 1 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 1.670476e-03 | 2.777 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.856845e-03 | 2.731 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.914008e-03 | 2.718 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 1.942500e-03 | 2.712 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.974215e-03 | 2.705 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.012779e-03 | 2.696 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.012779e-03 | 2.696 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 2.145186e-03 | 2.669 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 1.995666e-03 | 2.700 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 2.388761e-03 | 2.622 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 2.464153e-03 | 2.608 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 2.490600e-03 | 2.604 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 2.629897e-03 | 2.580 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 2.629897e-03 | 2.580 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 2.950515e-03 | 2.530 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 3.048569e-03 | 2.516 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 2.964543e-03 | 2.528 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 3.332880e-03 | 2.477 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 3.347983e-03 | 2.475 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.545303e-03 | 2.450 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 3.545303e-03 | 2.450 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 3.667441e-03 | 2.436 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 3.667441e-03 | 2.436 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 3.716727e-03 | 2.430 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 4.004195e-03 | 2.397 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 4.020639e-03 | 2.396 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 4.184459e-03 | 2.378 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 3.853075e-03 | 2.414 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 4.004195e-03 | 2.397 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 4.215626e-03 | 2.375 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 4.386384e-03 | 2.358 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 4.465710e-03 | 2.350 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 4.547374e-03 | 2.342 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 4.630817e-03 | 2.334 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 4.630817e-03 | 2.334 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 4.660063e-03 | 2.332 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 4.682298e-03 | 2.330 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 4.944924e-03 | 2.306 | 1 | 1 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 5.439893e-03 | 2.264 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 5.439893e-03 | 2.264 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 5.543020e-03 | 2.256 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 5.641878e-03 | 2.249 | 1 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 5.641878e-03 | 2.249 | 1 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 5.200443e-03 | 2.284 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 5.668763e-03 | 2.247 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 5.707494e-03 | 2.244 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 5.707494e-03 | 2.244 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 5.781069e-03 | 2.238 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 5.813994e-03 | 2.236 | 1 | 1 |
| Cellular Senescence | R-HSA-2559583 | 5.922839e-03 | 2.227 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 6.342840e-03 | 2.198 | 1 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 6.372445e-03 | 2.196 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 6.461913e-03 | 2.190 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 6.461913e-03 | 2.190 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 6.461913e-03 | 2.190 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 6.760853e-03 | 2.170 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 6.760853e-03 | 2.170 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 6.760853e-03 | 2.170 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 6.901105e-03 | 2.161 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 7.266956e-03 | 2.139 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 6.962181e-03 | 2.157 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 7.149481e-03 | 2.146 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 6.863535e-03 | 2.163 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 7.325004e-03 | 2.135 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 7.460457e-03 | 2.127 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 7.889402e-03 | 2.103 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 7.993976e-03 | 2.097 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 8.084831e-03 | 2.092 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 8.186591e-03 | 2.087 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 8.246244e-03 | 2.084 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 8.246244e-03 | 2.084 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 8.307458e-03 | 2.081 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.307458e-03 | 2.081 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 8.307458e-03 | 2.081 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 8.454290e-03 | 2.073 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 8.663923e-03 | 2.062 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 8.799276e-03 | 2.056 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 8.829545e-03 | 2.054 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 9.020869e-03 | 2.045 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 9.828653e-03 | 2.008 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 9.828653e-03 | 2.008 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 1.139090e-02 | 1.943 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 1.139090e-02 | 1.943 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 1.127861e-02 | 1.948 | 1 | 1 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 1.037968e-02 | 1.984 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 1.139090e-02 | 1.943 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.155919e-02 | 1.937 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 1.160545e-02 | 1.935 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.218470e-02 | 1.914 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 1.218470e-02 | 1.914 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 1.247295e-02 | 1.904 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 1.270278e-02 | 1.896 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.272519e-02 | 1.895 | 1 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 1.298661e-02 | 1.887 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 1.314553e-02 | 1.881 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 1.314553e-02 | 1.881 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 1.355224e-02 | 1.868 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 1.386791e-02 | 1.858 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 1.386791e-02 | 1.858 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 1.437009e-02 | 1.843 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.437084e-02 | 1.843 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 1.452018e-02 | 1.838 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.486905e-02 | 1.828 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 1.502372e-02 | 1.823 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.546533e-02 | 1.811 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 1.768040e-02 | 1.753 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 1.768040e-02 | 1.753 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 1.621792e-02 | 1.790 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 1.621792e-02 | 1.790 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 1.570655e-02 | 1.804 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 1.759226e-02 | 1.755 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 1.768040e-02 | 1.753 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.700781e-02 | 1.769 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.632913e-02 | 1.787 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.632913e-02 | 1.787 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.715443e-02 | 1.766 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.783356e-02 | 1.749 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 1.794115e-02 | 1.746 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 1.815029e-02 | 1.741 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 1.816353e-02 | 1.741 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 1.860847e-02 | 1.730 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.882274e-02 | 1.725 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.891932e-02 | 1.723 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.891932e-02 | 1.723 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.901887e-02 | 1.721 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.955388e-02 | 1.709 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 2.087667e-02 | 1.680 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 2.099079e-02 | 1.678 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 2.138715e-02 | 1.670 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 2.200368e-02 | 1.658 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 2.203752e-02 | 1.657 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 2.213383e-02 | 1.655 | 1 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 2.236423e-02 | 1.650 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 2.289214e-02 | 1.640 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.310325e-02 | 1.636 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.310325e-02 | 1.636 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.356128e-02 | 1.628 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 2.411448e-02 | 1.618 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 2.546155e-02 | 1.594 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 2.546155e-02 | 1.594 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.488104e-02 | 1.604 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 2.849971e-02 | 1.545 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 2.488104e-02 | 1.604 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 2.795864e-02 | 1.553 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 2.521958e-02 | 1.598 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 2.670490e-02 | 1.573 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 2.493396e-02 | 1.603 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.512391e-02 | 1.600 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.576874e-02 | 1.589 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 2.576874e-02 | 1.589 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 2.607130e-02 | 1.584 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 2.853301e-02 | 1.545 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 2.868781e-02 | 1.542 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 2.868781e-02 | 1.542 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 2.888482e-02 | 1.539 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.981648e-02 | 1.526 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 3.028164e-02 | 1.519 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 3.028164e-02 | 1.519 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.028164e-02 | 1.519 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 3.029894e-02 | 1.519 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 3.074645e-02 | 1.512 | 1 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 3.121995e-02 | 1.506 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 3.121995e-02 | 1.506 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 3.121995e-02 | 1.506 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 3.121995e-02 | 1.506 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 3.121995e-02 | 1.506 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 3.838089e-02 | 1.416 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 3.838089e-02 | 1.416 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 3.838089e-02 | 1.416 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 3.838089e-02 | 1.416 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 3.578259e-02 | 1.446 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 3.578259e-02 | 1.446 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 3.578259e-02 | 1.446 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 3.641895e-02 | 1.439 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 3.641895e-02 | 1.439 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 3.641895e-02 | 1.439 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 3.641895e-02 | 1.439 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 3.580806e-02 | 1.446 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 3.310909e-02 | 1.480 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 3.310909e-02 | 1.480 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 3.811087e-02 | 1.419 | 1 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.733178e-02 | 1.428 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.580806e-02 | 1.446 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 3.838089e-02 | 1.416 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 3.838089e-02 | 1.416 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 3.221966e-02 | 1.492 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 3.704793e-02 | 1.431 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 3.691689e-02 | 1.433 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 3.838089e-02 | 1.416 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 3.372725e-02 | 1.472 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 3.691689e-02 | 1.433 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 3.372725e-02 | 1.472 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 3.372725e-02 | 1.472 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 3.733178e-02 | 1.428 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 3.221966e-02 | 1.492 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 3.733178e-02 | 1.428 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 3.524647e-02 | 1.453 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 3.522416e-02 | 1.453 | 1 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 3.845784e-02 | 1.415 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 3.892007e-02 | 1.410 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 3.892007e-02 | 1.410 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 3.892007e-02 | 1.410 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 3.956985e-02 | 1.403 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 3.956985e-02 | 1.403 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 4.130824e-02 | 1.384 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 4.133027e-02 | 1.384 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 4.206796e-02 | 1.376 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 4.220485e-02 | 1.375 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 4.330916e-02 | 1.363 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 4.370714e-02 | 1.359 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 4.381927e-02 | 1.358 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 4.424314e-02 | 1.354 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 4.461129e-02 | 1.351 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 4.605091e-02 | 1.337 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 4.629888e-02 | 1.334 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 4.668288e-02 | 1.331 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 4.668288e-02 | 1.331 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 4.674116e-02 | 1.330 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 4.735136e-02 | 1.325 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 4.736907e-02 | 1.325 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 4.768861e-02 | 1.322 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 4.773358e-02 | 1.321 | 1 | 1 |
| Adrenoceptors | R-HSA-390696 | 4.773358e-02 | 1.321 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 4.814603e-02 | 1.317 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 4.880359e-02 | 1.312 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 4.880359e-02 | 1.312 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 5.291736e-02 | 1.276 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 5.291736e-02 | 1.276 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 5.291736e-02 | 1.276 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 5.582657e-02 | 1.253 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 5.582657e-02 | 1.253 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 5.582657e-02 | 1.253 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 5.582657e-02 | 1.253 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 6.162722e-02 | 1.210 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 6.003502e-02 | 1.222 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 5.591913e-02 | 1.252 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 5.952968e-02 | 1.225 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 6.100070e-02 | 1.215 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 6.100070e-02 | 1.215 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 6.112685e-02 | 1.214 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 5.183251e-02 | 1.285 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 5.149955e-02 | 1.288 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 5.395329e-02 | 1.268 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 5.909895e-02 | 1.228 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 5.851992e-02 | 1.233 | 0 | 0 |
| S Phase | R-HSA-69242 | 5.975905e-02 | 1.224 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 5.580847e-02 | 1.253 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 6.039113e-02 | 1.219 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 5.291736e-02 | 1.276 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 5.395329e-02 | 1.268 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 5.975905e-02 | 1.224 | 1 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 4.940202e-02 | 1.306 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 5.318961e-02 | 1.274 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 5.318961e-02 | 1.274 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 5.952968e-02 | 1.225 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 6.162722e-02 | 1.210 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 5.909895e-02 | 1.228 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 5.909895e-02 | 1.228 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 5.881293e-02 | 1.231 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 5.149955e-02 | 1.288 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 5.994488e-02 | 1.222 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.851992e-02 | 1.233 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 6.345997e-02 | 1.198 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 6.588495e-02 | 1.181 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 6.617924e-02 | 1.179 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 6.617924e-02 | 1.179 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 6.617924e-02 | 1.179 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 6.667627e-02 | 1.176 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 6.667627e-02 | 1.176 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 6.695483e-02 | 1.174 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 6.873175e-02 | 1.163 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 6.885901e-02 | 1.162 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 6.885901e-02 | 1.162 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 6.888163e-02 | 1.162 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 6.957443e-02 | 1.158 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 6.995900e-02 | 1.155 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 7.233655e-02 | 1.141 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 7.259745e-02 | 1.139 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 7.261188e-02 | 1.139 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 7.261188e-02 | 1.139 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 7.261188e-02 | 1.139 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 7.425627e-02 | 1.129 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 7.637975e-02 | 1.117 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 7.637975e-02 | 1.117 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 7.637975e-02 | 1.117 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 7.637975e-02 | 1.117 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 7.637975e-02 | 1.117 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 7.637975e-02 | 1.117 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 7.637975e-02 | 1.117 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 7.637975e-02 | 1.117 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 7.637975e-02 | 1.117 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 7.722387e-02 | 1.112 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 7.722387e-02 | 1.112 | 1 | 1 |
| Signalling to ERKs | R-HSA-187687 | 7.722387e-02 | 1.112 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 7.741630e-02 | 1.111 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 7.746463e-02 | 1.111 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 7.746463e-02 | 1.111 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 7.861134e-02 | 1.105 | 1 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 7.867592e-02 | 1.104 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 7.901363e-02 | 1.102 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 7.909508e-02 | 1.102 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 8.002575e-02 | 1.097 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 8.006824e-02 | 1.097 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 8.144659e-02 | 1.089 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 8.323395e-02 | 1.080 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 8.458420e-02 | 1.073 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 8.521591e-02 | 1.069 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 8.521591e-02 | 1.069 | 1 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 8.697253e-02 | 1.061 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 8.697253e-02 | 1.061 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 8.697253e-02 | 1.061 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 8.697253e-02 | 1.061 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 8.697253e-02 | 1.061 | 0 | 0 |
| Signaling by RAS GAP mutants | R-HSA-9753510 | 8.697253e-02 | 1.061 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 9.974200e-02 | 1.001 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 9.974200e-02 | 1.001 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 9.501749e-02 | 1.022 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 9.501749e-02 | 1.022 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 9.501749e-02 | 1.022 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 9.501749e-02 | 1.022 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 9.501749e-02 | 1.022 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 9.501749e-02 | 1.022 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 9.501749e-02 | 1.022 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 8.651244e-02 | 1.063 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.016973e-01 | 0.993 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 1.016973e-01 | 0.993 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 8.999051e-02 | 1.046 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 1.017799e-01 | 0.992 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 8.791135e-02 | 1.056 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 1.039698e-01 | 0.983 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 1.062171e-01 | 0.974 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 1.138205e-01 | 0.944 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 9.187767e-02 | 1.037 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 9.974200e-02 | 1.001 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 9.959073e-02 | 1.002 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 8.912262e-02 | 1.050 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 9.910101e-02 | 1.004 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.103319e-01 | 0.957 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 8.615643e-02 | 1.065 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 8.615643e-02 | 1.065 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 1.138205e-01 | 0.944 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 9.368562e-02 | 1.028 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 9.625521e-02 | 1.017 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 9.625521e-02 | 1.017 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 8.615643e-02 | 1.065 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 1.010366e-01 | 0.996 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.103296e-01 | 0.957 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.103319e-01 | 0.957 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 9.434738e-02 | 1.025 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 1.090957e-01 | 0.962 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 8.651244e-02 | 1.063 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 8.976579e-02 | 1.047 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 1.021067e-01 | 0.991 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 8.697253e-02 | 1.061 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 9.646435e-02 | 1.016 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 9.415179e-02 | 1.026 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 8.783818e-02 | 1.056 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 8.854616e-02 | 1.053 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 8.615643e-02 | 1.065 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 1.103319e-01 | 0.957 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.143178e-01 | 0.942 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 1.143178e-01 | 0.942 | 1 | 1 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.143178e-01 | 0.942 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 1.143178e-01 | 0.942 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 1.143655e-01 | 0.942 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.151536e-01 | 0.939 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.151536e-01 | 0.939 | 0 | 0 |
| Deletions in the AXIN1 gene destabilize the destruction complex | R-HSA-5467345 | 1.151536e-01 | 0.939 | 0 | 0 |
| Deletions in the AMER1 gene destabilize the destruction complex | R-HSA-5467343 | 1.151536e-01 | 0.939 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.172175e-01 | 0.931 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 1.173261e-01 | 0.931 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 1.173261e-01 | 0.931 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 1.173261e-01 | 0.931 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 1.181114e-01 | 0.928 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.208836e-01 | 0.918 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.236967e-01 | 0.908 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 1.255678e-01 | 0.901 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 1.255678e-01 | 0.901 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 1.255678e-01 | 0.901 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.255678e-01 | 0.901 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 1.255678e-01 | 0.901 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 1.255678e-01 | 0.901 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.255678e-01 | 0.901 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 1.255678e-01 | 0.901 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 1.255678e-01 | 0.901 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 1.257446e-01 | 0.901 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 1.257446e-01 | 0.901 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 1.257446e-01 | 0.901 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 1.257446e-01 | 0.901 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 1.284626e-01 | 0.891 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 1.325173e-01 | 0.878 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.325173e-01 | 0.878 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 1.329279e-01 | 0.876 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 1.341624e-01 | 0.872 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.341624e-01 | 0.872 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.346027e-01 | 0.871 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 1.347649e-01 | 0.870 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.347649e-01 | 0.870 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.351809e-01 | 0.869 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.351809e-01 | 0.869 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 1.351809e-01 | 0.869 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.351809e-01 | 0.869 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.351809e-01 | 0.869 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.351809e-01 | 0.869 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.351809e-01 | 0.869 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 1.351809e-01 | 0.869 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 1.351809e-01 | 0.869 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 1.356859e-01 | 0.867 | 0 | 0 |
| Kinesins | R-HSA-983189 | 1.358527e-01 | 0.867 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.368452e-01 | 0.864 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.370207e-01 | 0.863 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 1.372976e-01 | 0.862 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.373427e-01 | 0.862 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 1.415364e-01 | 0.849 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 1.418298e-01 | 0.848 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 1.418298e-01 | 0.848 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 1.418298e-01 | 0.848 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 1.418298e-01 | 0.848 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.676969e-01 | 0.775 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.676969e-01 | 0.775 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 1.676969e-01 | 0.775 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.676969e-01 | 0.775 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 1.676969e-01 | 0.775 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 1.676969e-01 | 0.775 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 2.115837e-01 | 0.675 | 0 | 0 |
| IRS activation | R-HSA-74713 | 2.115837e-01 | 0.675 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 2.115837e-01 | 0.675 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 2.115837e-01 | 0.675 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 1.534881e-01 | 0.814 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 1.534881e-01 | 0.814 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.534881e-01 | 0.814 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.534881e-01 | 0.814 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 1.831274e-01 | 0.737 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 1.831274e-01 | 0.737 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 1.831274e-01 | 0.737 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.831274e-01 | 0.737 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 1.574528e-01 | 0.803 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 1.574528e-01 | 0.803 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.574528e-01 | 0.803 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 1.574528e-01 | 0.803 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 1.574528e-01 | 0.803 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 1.574528e-01 | 0.803 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 2.141176e-01 | 0.669 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 1.809677e-01 | 0.742 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.809677e-01 | 0.742 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 1.809677e-01 | 0.742 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 1.543406e-01 | 0.812 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 2.055525e-01 | 0.687 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 2.055525e-01 | 0.687 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 2.055525e-01 | 0.687 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 2.055525e-01 | 0.687 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.055525e-01 | 0.687 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 1.945243e-01 | 0.711 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 1.721385e-01 | 0.764 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 2.015339e-01 | 0.696 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 1.671570e-01 | 0.777 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 1.445332e-01 | 0.840 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.047720e-01 | 0.689 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.666538e-01 | 0.778 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 1.429662e-01 | 0.845 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 1.563539e-01 | 0.806 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 1.436241e-01 | 0.843 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 1.485898e-01 | 0.828 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.566804e-01 | 0.805 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 1.574528e-01 | 0.803 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 2.141176e-01 | 0.669 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.773769e-01 | 0.751 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 2.141176e-01 | 0.669 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 1.760242e-01 | 0.754 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.434403e-01 | 0.843 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 2.115837e-01 | 0.675 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 2.141176e-01 | 0.669 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.831599e-01 | 0.737 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.831599e-01 | 0.737 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 1.666538e-01 | 0.778 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 1.783424e-01 | 0.749 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 1.769794e-01 | 0.752 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 1.789654e-01 | 0.747 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 1.498780e-01 | 0.824 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.721385e-01 | 0.764 | 1 | 1 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 1.676969e-01 | 0.775 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 1.831274e-01 | 0.737 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 1.485898e-01 | 0.828 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 1.882619e-01 | 0.725 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.831599e-01 | 0.737 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.654905e-01 | 0.781 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.017203e-01 | 0.695 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.809974e-01 | 0.742 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 1.645360e-01 | 0.784 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.594134e-01 | 0.797 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 2.052684e-01 | 0.688 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 1.676969e-01 | 0.775 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 2.115837e-01 | 0.675 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 2.115837e-01 | 0.675 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.831274e-01 | 0.737 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 1.809677e-01 | 0.742 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 1.566471e-01 | 0.805 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 2.049714e-01 | 0.688 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 1.518836e-01 | 0.818 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 2.033291e-01 | 0.692 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 1.676969e-01 | 0.775 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.671679e-01 | 0.777 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.482838e-01 | 0.829 | 1 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 2.055525e-01 | 0.687 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 2.055525e-01 | 0.687 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 1.569762e-01 | 0.804 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 1.919419e-01 | 0.717 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 1.739857e-01 | 0.759 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 2.049714e-01 | 0.688 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 1.676969e-01 | 0.775 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.597344e-01 | 0.797 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 1.994091e-01 | 0.700 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.658346e-01 | 0.780 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 1.831274e-01 | 0.737 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 1.781092e-01 | 0.749 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 1.557445e-01 | 0.808 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.789654e-01 | 0.747 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 1.534881e-01 | 0.814 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 1.831274e-01 | 0.737 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 1.809677e-01 | 0.742 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 2.055525e-01 | 0.687 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 1.739857e-01 | 0.759 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 2.052684e-01 | 0.688 | 1 | 1 |
| Gene Silencing by RNA | R-HSA-211000 | 1.499249e-01 | 0.824 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 2.115837e-01 | 0.675 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 2.015339e-01 | 0.696 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 1.831274e-01 | 0.737 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.887333e-01 | 0.724 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 2.158543e-01 | 0.666 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 2.158543e-01 | 0.666 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 2.158543e-01 | 0.666 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 2.158543e-01 | 0.666 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 2.158543e-01 | 0.666 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 2.166028e-01 | 0.664 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.170529e-01 | 0.663 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.170529e-01 | 0.663 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.170529e-01 | 0.663 | 0 | 0 |
| Impaired BRCA2 binding to SEM1 (DSS1) | R-HSA-9763198 | 2.170529e-01 | 0.663 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.170529e-01 | 0.663 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.170529e-01 | 0.663 | 0 | 0 |
| Defective F8 binding to von Willebrand factor | R-HSA-9672393 | 2.170529e-01 | 0.663 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.170529e-01 | 0.663 | 0 | 0 |
| Impaired BRCA2 translocation to the nucleus | R-HSA-9709275 | 2.170529e-01 | 0.663 | 0 | 0 |
| Hereditary fructose intolerance | R-HSA-5657560 | 2.170529e-01 | 0.663 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 2.170529e-01 | 0.663 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 2.170529e-01 | 0.663 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.170529e-01 | 0.663 | 0 | 0 |
| Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) | R-HSA-5619110 | 2.170529e-01 | 0.663 | 0 | 0 |
| SDK interactions | R-HSA-373756 | 2.170529e-01 | 0.663 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 2.181789e-01 | 0.661 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 2.202039e-01 | 0.657 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 2.205444e-01 | 0.657 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 2.205444e-01 | 0.657 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 2.221187e-01 | 0.653 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 2.221187e-01 | 0.653 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 2.222184e-01 | 0.653 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 2.285571e-01 | 0.641 | 0 | 0 |
| Signaling by FGFR3 fusions in cancer | R-HSA-8853334 | 3.072226e-01 | 0.513 | 0 | 0 |
| t(4;14) translocations of FGFR3 | R-HSA-2033515 | 3.072226e-01 | 0.513 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 3.072226e-01 | 0.513 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 3.072226e-01 | 0.513 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 3.072226e-01 | 0.513 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 3.072226e-01 | 0.513 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5660724 | 3.072226e-01 | 0.513 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 3.072226e-01 | 0.513 | 0 | 0 |
| Defective SLC12A3 causes Gitelman syndrome (GS) | R-HSA-5619087 | 3.072226e-01 | 0.513 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5619081 | 3.072226e-01 | 0.513 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 3.072226e-01 | 0.513 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 3.072226e-01 | 0.513 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 3.072226e-01 | 0.513 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 2.564038e-01 | 0.591 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 2.564038e-01 | 0.591 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 2.564038e-01 | 0.591 | 0 | 0 |
| NGF-independant TRKA activation | R-HSA-187024 | 2.564038e-01 | 0.591 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.564038e-01 | 0.591 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 2.564038e-01 | 0.591 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 3.870124e-01 | 0.412 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 3.870124e-01 | 0.412 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 3.870124e-01 | 0.412 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.870124e-01 | 0.412 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 3.870124e-01 | 0.412 | 0 | 0 |
| TWIK related potassium channel (TREK) | R-HSA-1299503 | 3.870124e-01 | 0.412 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 3.870124e-01 | 0.412 | 0 | 0 |
| Defective visual phototransduction due to STRA6 loss of function | R-HSA-9918449 | 3.870124e-01 | 0.412 | 0 | 0 |
| Defective F8 cleavage by thrombin | R-HSA-9672391 | 3.870124e-01 | 0.412 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 3.013608e-01 | 0.521 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 3.013608e-01 | 0.521 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 3.013608e-01 | 0.521 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 3.013608e-01 | 0.521 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 3.013608e-01 | 0.521 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.461064e-01 | 0.609 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 2.787644e-01 | 0.555 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 2.787644e-01 | 0.555 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.458291e-01 | 0.461 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 3.458291e-01 | 0.461 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 3.458291e-01 | 0.461 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 3.458291e-01 | 0.461 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 4.576167e-01 | 0.339 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 4.576167e-01 | 0.339 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 4.576167e-01 | 0.339 | 0 | 0 |
| Defective DPM2 causes DPM2-CDG | R-HSA-4719377 | 4.576167e-01 | 0.339 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 4.576167e-01 | 0.339 | 0 | 0 |
| Defective DPM1 causes DPM1-CDG | R-HSA-4717374 | 4.576167e-01 | 0.339 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 4.576167e-01 | 0.339 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 4.576167e-01 | 0.339 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 4.576167e-01 | 0.339 | 0 | 0 |
| Defective DPM3 causes DPM3-CDG | R-HSA-4719360 | 4.576167e-01 | 0.339 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 2.572280e-01 | 0.590 | 1 | 1 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 2.572280e-01 | 0.590 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 2.572280e-01 | 0.590 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 3.117888e-01 | 0.506 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 3.117888e-01 | 0.506 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 3.117888e-01 | 0.506 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 2.378701e-01 | 0.624 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 2.378701e-01 | 0.624 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.839715e-01 | 0.547 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 3.893252e-01 | 0.410 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 3.893252e-01 | 0.410 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 3.893252e-01 | 0.410 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 2.604644e-01 | 0.584 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 3.449061e-01 | 0.462 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 3.449061e-01 | 0.462 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 3.449061e-01 | 0.462 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 3.449061e-01 | 0.462 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 3.110960e-01 | 0.507 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 3.384442e-01 | 0.471 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 3.384442e-01 | 0.471 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 3.778726e-01 | 0.423 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 4.314836e-01 | 0.365 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 4.314836e-01 | 0.365 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 4.314836e-01 | 0.365 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 4.314836e-01 | 0.365 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 4.314836e-01 | 0.365 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 3.658680e-01 | 0.437 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 3.658680e-01 | 0.437 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 2.955322e-01 | 0.529 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 2.474805e-01 | 0.606 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 4.104748e-01 | 0.387 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 4.104748e-01 | 0.387 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 3.932302e-01 | 0.405 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 3.932302e-01 | 0.405 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 3.784252e-01 | 0.422 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 4.425282e-01 | 0.354 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 3.427367e-01 | 0.465 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 3.427367e-01 | 0.465 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 4.204052e-01 | 0.376 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 3.327613e-01 | 0.478 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 2.987812e-01 | 0.525 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 3.608441e-01 | 0.443 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.296289e-01 | 0.482 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 4.083005e-01 | 0.389 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 4.472787e-01 | 0.349 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 3.491643e-01 | 0.457 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.431321e-01 | 0.614 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 2.690125e-01 | 0.570 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 2.487600e-01 | 0.604 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.519416e-01 | 0.345 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 4.515805e-01 | 0.345 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 3.011668e-01 | 0.521 | 0 | 0 |
| Protein folding | R-HSA-391251 | 2.724037e-01 | 0.565 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 4.349318e-01 | 0.362 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 2.601889e-01 | 0.585 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 3.868214e-01 | 0.412 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 4.519745e-01 | 0.345 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 2.806759e-01 | 0.552 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 3.932302e-01 | 0.405 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 3.545060e-01 | 0.450 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 4.496981e-01 | 0.347 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 2.359952e-01 | 0.627 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 3.226089e-01 | 0.491 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.439086e-01 | 0.464 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 3.439086e-01 | 0.464 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 2.806759e-01 | 0.552 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 2.766631e-01 | 0.558 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 3.784252e-01 | 0.422 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 3.247626e-01 | 0.488 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 4.516589e-01 | 0.345 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 3.617083e-01 | 0.442 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 3.542575e-01 | 0.451 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 3.237763e-01 | 0.490 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 3.117888e-01 | 0.506 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 3.069645e-01 | 0.513 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 3.069645e-01 | 0.513 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 4.425282e-01 | 0.354 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 2.401204e-01 | 0.620 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 2.543237e-01 | 0.595 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 2.654341e-01 | 0.576 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 3.759316e-01 | 0.425 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 2.839715e-01 | 0.547 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 4.104748e-01 | 0.387 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 4.425282e-01 | 0.354 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 4.083005e-01 | 0.389 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 4.472787e-01 | 0.349 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 4.472787e-01 | 0.349 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 4.055896e-01 | 0.392 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 3.110960e-01 | 0.507 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 3.865818e-01 | 0.413 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 3.845424e-01 | 0.415 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 2.676928e-01 | 0.572 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 2.564038e-01 | 0.591 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 2.787644e-01 | 0.555 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 3.384442e-01 | 0.471 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 3.384442e-01 | 0.471 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 2.298244e-01 | 0.639 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 4.204052e-01 | 0.376 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 3.496154e-01 | 0.456 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 2.893855e-01 | 0.539 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 3.306525e-01 | 0.481 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 4.046427e-01 | 0.393 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 3.449061e-01 | 0.462 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 3.073634e-01 | 0.512 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 2.564038e-01 | 0.591 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 2.572280e-01 | 0.590 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 3.110960e-01 | 0.507 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 4.314836e-01 | 0.365 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 3.658680e-01 | 0.437 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 3.535316e-01 | 0.452 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 3.790425e-01 | 0.421 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 3.636042e-01 | 0.439 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 4.155492e-01 | 0.381 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.913224e-01 | 0.536 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 4.368130e-01 | 0.360 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 2.712272e-01 | 0.567 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 3.696356e-01 | 0.432 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 2.572280e-01 | 0.590 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 2.804229e-01 | 0.552 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 2.572280e-01 | 0.590 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 3.658680e-01 | 0.437 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 3.050914e-01 | 0.516 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.310311e-01 | 0.636 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 4.104748e-01 | 0.387 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 4.261033e-01 | 0.370 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 2.550572e-01 | 0.593 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 2.399515e-01 | 0.620 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 4.496981e-01 | 0.347 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 2.609265e-01 | 0.583 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 2.604644e-01 | 0.584 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 4.314836e-01 | 0.365 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 4.104748e-01 | 0.387 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 3.545060e-01 | 0.450 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 2.832357e-01 | 0.548 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 3.340212e-01 | 0.476 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 3.754208e-01 | 0.425 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 3.658680e-01 | 0.437 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 2.855324e-01 | 0.544 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 2.339756e-01 | 0.631 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 3.893252e-01 | 0.410 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 4.087506e-01 | 0.389 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 4.477152e-01 | 0.349 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 2.621876e-01 | 0.581 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 4.472787e-01 | 0.349 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.927091e-01 | 0.406 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 3.530156e-01 | 0.452 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 3.306525e-01 | 0.481 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 2.662135e-01 | 0.575 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 2.292524e-01 | 0.640 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 2.662135e-01 | 0.575 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 2.662135e-01 | 0.575 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 2.757750e-01 | 0.559 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.072226e-01 | 0.513 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 3.870124e-01 | 0.412 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 3.870124e-01 | 0.412 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 2.461064e-01 | 0.609 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 2.787644e-01 | 0.555 | 0 | 0 |
| Activation of TRKA receptors | R-HSA-187015 | 3.458291e-01 | 0.461 | 0 | 0 |
| Adenosine P1 receptors | R-HSA-417973 | 4.576167e-01 | 0.339 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 3.893252e-01 | 0.410 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 3.893252e-01 | 0.410 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 3.893252e-01 | 0.410 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 3.110960e-01 | 0.507 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 4.314836e-01 | 0.365 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 4.314836e-01 | 0.365 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 4.314836e-01 | 0.365 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 3.439086e-01 | 0.464 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 3.932302e-01 | 0.405 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 2.809367e-01 | 0.551 | 1 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 4.234304e-01 | 0.373 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 3.774573e-01 | 0.423 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.104748e-01 | 0.387 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 4.520004e-01 | 0.345 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 3.439086e-01 | 0.464 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 2.957255e-01 | 0.529 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 3.206154e-01 | 0.494 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 2.725957e-01 | 0.564 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.378701e-01 | 0.624 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 4.261033e-01 | 0.370 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 3.013608e-01 | 0.521 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 3.117888e-01 | 0.506 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 3.893252e-01 | 0.410 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 2.654341e-01 | 0.576 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 3.712007e-01 | 0.430 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 2.378701e-01 | 0.624 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 3.545060e-01 | 0.450 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 3.247626e-01 | 0.488 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.310311e-01 | 0.636 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 2.835299e-01 | 0.547 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 3.870124e-01 | 0.412 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 4.576167e-01 | 0.339 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 2.604644e-01 | 0.584 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 3.327613e-01 | 0.478 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.117888e-01 | 0.506 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 3.013608e-01 | 0.521 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 4.314836e-01 | 0.365 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 3.870124e-01 | 0.412 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 3.458291e-01 | 0.461 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 4.576167e-01 | 0.339 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 4.362702e-01 | 0.360 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 3.431054e-01 | 0.465 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 2.606096e-01 | 0.584 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 4.023193e-01 | 0.395 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 3.458291e-01 | 0.461 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 4.314836e-01 | 0.365 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.653356e-01 | 0.437 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 2.601889e-01 | 0.585 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 2.788564e-01 | 0.555 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 3.449061e-01 | 0.462 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 4.314836e-01 | 0.365 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 3.778726e-01 | 0.423 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 4.613020e-01 | 0.336 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 4.641855e-01 | 0.333 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 4.678821e-01 | 0.330 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 4.689383e-01 | 0.329 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 4.700029e-01 | 0.328 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 4.710627e-01 | 0.327 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 4.710627e-01 | 0.327 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 4.720354e-01 | 0.326 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 4.720354e-01 | 0.326 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 4.720354e-01 | 0.326 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 4.720354e-01 | 0.326 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 4.720354e-01 | 0.326 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 4.720354e-01 | 0.326 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 4.720354e-01 | 0.326 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 4.720354e-01 | 0.326 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 4.720354e-01 | 0.326 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 4.720354e-01 | 0.326 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 4.720354e-01 | 0.326 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 4.720354e-01 | 0.326 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 4.720910e-01 | 0.326 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 4.720910e-01 | 0.326 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 4.730307e-01 | 0.325 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 4.730307e-01 | 0.325 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 4.737486e-01 | 0.324 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 4.737486e-01 | 0.324 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 4.738762e-01 | 0.324 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 4.738762e-01 | 0.324 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 4.738762e-01 | 0.324 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 4.738762e-01 | 0.324 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 4.772499e-01 | 0.321 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 4.788855e-01 | 0.320 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 4.857946e-01 | 0.314 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 4.857946e-01 | 0.314 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 4.902909e-01 | 0.310 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 4.960347e-01 | 0.304 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 4.997246e-01 | 0.301 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 4.997246e-01 | 0.301 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 4.997246e-01 | 0.301 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 5.039032e-01 | 0.298 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 5.039532e-01 | 0.298 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 5.043884e-01 | 0.297 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 5.043884e-01 | 0.297 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 5.043884e-01 | 0.297 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 5.043884e-01 | 0.297 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 5.043884e-01 | 0.297 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 5.043884e-01 | 0.297 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 5.043884e-01 | 0.297 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 5.056862e-01 | 0.296 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 5.093051e-01 | 0.293 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 5.107916e-01 | 0.292 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 5.107916e-01 | 0.292 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 5.107916e-01 | 0.292 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 5.115789e-01 | 0.291 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 5.117566e-01 | 0.291 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 5.118886e-01 | 0.291 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 5.121175e-01 | 0.291 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 5.135368e-01 | 0.289 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 5.135368e-01 | 0.289 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 5.135368e-01 | 0.289 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 5.135368e-01 | 0.289 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 5.135368e-01 | 0.289 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 5.135368e-01 | 0.289 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 5.135368e-01 | 0.289 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 5.143381e-01 | 0.289 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 5.154041e-01 | 0.288 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.154041e-01 | 0.288 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 5.186502e-01 | 0.285 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 5.186502e-01 | 0.285 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 5.186502e-01 | 0.285 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 5.200923e-01 | 0.284 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 5.200923e-01 | 0.284 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 5.200923e-01 | 0.284 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 5.200923e-01 | 0.284 | 0 | 0 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling | R-HSA-2644607 | 5.200923e-01 | 0.284 | 0 | 0 |
| FBXW7 Mutants and NOTCH1 in Cancer | R-HSA-2644605 | 5.200923e-01 | 0.284 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 5.200923e-01 | 0.284 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 5.200923e-01 | 0.284 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 5.232462e-01 | 0.281 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 5.232462e-01 | 0.281 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 5.251280e-01 | 0.280 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 5.251280e-01 | 0.280 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 5.251280e-01 | 0.280 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 5.251280e-01 | 0.280 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 5.269757e-01 | 0.278 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 5.280696e-01 | 0.277 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 5.337935e-01 | 0.273 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 5.337935e-01 | 0.273 | 0 | 0 |
| PKA activation | R-HSA-163615 | 5.339583e-01 | 0.272 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 5.339583e-01 | 0.272 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 5.339583e-01 | 0.272 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 5.339583e-01 | 0.272 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 5.362685e-01 | 0.271 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 5.383354e-01 | 0.269 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 5.383467e-01 | 0.269 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 5.386903e-01 | 0.269 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 5.408235e-01 | 0.267 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 5.408235e-01 | 0.267 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 5.408235e-01 | 0.267 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 5.416866e-01 | 0.266 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 5.432311e-01 | 0.265 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 5.476278e-01 | 0.262 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 5.476278e-01 | 0.262 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 5.476278e-01 | 0.262 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 5.476278e-01 | 0.262 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 5.476278e-01 | 0.262 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 5.476278e-01 | 0.262 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 5.476278e-01 | 0.262 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 5.491329e-01 | 0.260 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 5.498911e-01 | 0.260 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 5.498911e-01 | 0.260 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 5.498911e-01 | 0.260 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 5.498911e-01 | 0.260 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 5.498911e-01 | 0.260 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 5.536859e-01 | 0.257 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 5.536859e-01 | 0.257 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 5.536859e-01 | 0.257 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 5.536859e-01 | 0.257 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 5.576626e-01 | 0.254 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 5.585034e-01 | 0.253 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 5.603996e-01 | 0.252 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 5.603996e-01 | 0.252 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 5.625018e-01 | 0.250 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 5.625018e-01 | 0.250 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 5.625018e-01 | 0.250 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 5.625074e-01 | 0.250 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 5.625074e-01 | 0.250 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 5.625074e-01 | 0.250 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 5.625074e-01 | 0.250 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 5.675645e-01 | 0.246 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 5.731787e-01 | 0.242 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 5.731787e-01 | 0.242 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 5.736682e-01 | 0.241 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 5.739570e-01 | 0.241 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 5.739570e-01 | 0.241 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 5.744691e-01 | 0.241 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 5.753748e-01 | 0.240 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 5.753748e-01 | 0.240 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 5.753748e-01 | 0.240 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 5.753748e-01 | 0.240 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 5.753748e-01 | 0.240 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 5.753748e-01 | 0.240 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 5.753748e-01 | 0.240 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 5.753748e-01 | 0.240 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 5.753748e-01 | 0.240 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 5.753748e-01 | 0.240 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 5.753748e-01 | 0.240 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 5.753748e-01 | 0.240 | 0 | 0 |
| Inositol transporters | R-HSA-429593 | 5.753748e-01 | 0.240 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 5.753748e-01 | 0.240 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 5.818047e-01 | 0.235 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 5.824721e-01 | 0.235 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 5.824721e-01 | 0.235 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 5.824721e-01 | 0.235 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 5.824721e-01 | 0.235 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 5.824721e-01 | 0.235 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 5.824721e-01 | 0.235 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 5.824721e-01 | 0.235 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 5.824721e-01 | 0.235 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 5.825497e-01 | 0.235 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 5.825497e-01 | 0.235 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 5.825497e-01 | 0.235 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 5.825497e-01 | 0.235 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 5.836610e-01 | 0.234 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 5.836610e-01 | 0.234 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 5.840735e-01 | 0.234 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 5.847717e-01 | 0.233 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 5.899544e-01 | 0.229 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 5.899544e-01 | 0.229 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 5.909780e-01 | 0.228 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 5.909780e-01 | 0.228 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 5.909780e-01 | 0.228 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 5.909780e-01 | 0.228 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 5.909780e-01 | 0.228 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 5.922411e-01 | 0.228 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 5.957170e-01 | 0.225 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 5.957170e-01 | 0.225 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 5.972788e-01 | 0.224 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 5.972788e-01 | 0.224 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 5.972788e-01 | 0.224 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 5.972788e-01 | 0.224 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 6.007633e-01 | 0.221 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 6.042492e-01 | 0.219 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 6.042492e-01 | 0.219 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 6.056747e-01 | 0.218 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 6.058164e-01 | 0.218 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 6.071696e-01 | 0.217 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 6.152947e-01 | 0.211 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 6.152947e-01 | 0.211 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 6.152947e-01 | 0.211 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 6.152947e-01 | 0.211 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 6.152947e-01 | 0.211 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 6.162698e-01 | 0.210 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 6.162698e-01 | 0.210 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 6.162698e-01 | 0.210 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 6.198188e-01 | 0.208 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 6.201051e-01 | 0.208 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 6.242426e-01 | 0.205 | 1 | 1 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 6.242426e-01 | 0.205 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 6.242426e-01 | 0.205 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 6.242426e-01 | 0.205 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.242919e-01 | 0.205 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.242919e-01 | 0.205 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 6.242919e-01 | 0.205 | 0 | 0 |
| Defective CSF2RB causes SMDP5 | R-HSA-5688849 | 6.242919e-01 | 0.205 | 0 | 0 |
| Defective CSF2RA causes SMDP4 | R-HSA-5688890 | 6.242919e-01 | 0.205 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 6.242919e-01 | 0.205 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 6.242919e-01 | 0.205 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 6.242919e-01 | 0.205 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 6.242919e-01 | 0.205 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 6.242919e-01 | 0.205 | 0 | 0 |
| Synthesis of dolichyl-phosphate mannose | R-HSA-162699 | 6.242919e-01 | 0.205 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 6.242919e-01 | 0.205 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.242919e-01 | 0.205 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 6.242919e-01 | 0.205 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 6.242919e-01 | 0.205 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 6.242919e-01 | 0.205 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 6.242919e-01 | 0.205 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 6.242919e-01 | 0.205 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 6.286775e-01 | 0.202 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 6.289693e-01 | 0.201 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 6.289693e-01 | 0.201 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 6.289693e-01 | 0.201 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 6.289693e-01 | 0.201 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 6.289693e-01 | 0.201 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 6.289693e-01 | 0.201 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 6.289693e-01 | 0.201 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 6.308868e-01 | 0.200 | 1 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 6.316330e-01 | 0.200 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 6.337671e-01 | 0.198 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 6.337671e-01 | 0.198 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 6.414173e-01 | 0.193 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 6.414173e-01 | 0.193 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 6.414173e-01 | 0.193 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 6.414173e-01 | 0.193 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 6.436171e-01 | 0.191 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 6.442193e-01 | 0.191 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 6.460989e-01 | 0.190 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 6.460989e-01 | 0.190 | 0 | 0 |
| Synthesis of IPs in the nucleus | R-HSA-1855191 | 6.460989e-01 | 0.190 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 6.460989e-01 | 0.190 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 6.460989e-01 | 0.190 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 6.460989e-01 | 0.190 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 6.460989e-01 | 0.190 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 6.460989e-01 | 0.190 | 0 | 0 |
| Glycerophospholipid catabolism | R-HSA-6814848 | 6.460989e-01 | 0.190 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 6.465922e-01 | 0.189 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 6.500196e-01 | 0.187 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 6.595312e-01 | 0.181 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 6.623540e-01 | 0.179 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 6.623540e-01 | 0.179 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 6.623540e-01 | 0.179 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 6.624465e-01 | 0.179 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 6.624465e-01 | 0.179 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 6.628144e-01 | 0.179 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 6.631734e-01 | 0.178 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 6.653801e-01 | 0.177 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 6.653801e-01 | 0.177 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 6.653801e-01 | 0.177 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 6.658369e-01 | 0.177 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 6.675763e-01 | 0.175 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 6.675763e-01 | 0.175 | 0 | 0 |
| Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) | R-HSA-3656244 | 6.675763e-01 | 0.175 | 0 | 0 |
| Defective ST3GAL3 causes MCT12 and EIEE15 | R-HSA-3656243 | 6.675763e-01 | 0.175 | 0 | 0 |
| Defective CHST6 causes MCDC1 | R-HSA-3656225 | 6.675763e-01 | 0.175 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 6.675763e-01 | 0.175 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 6.675763e-01 | 0.175 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 6.675763e-01 | 0.175 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 6.675763e-01 | 0.175 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 6.675763e-01 | 0.175 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 6.675763e-01 | 0.175 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 6.713156e-01 | 0.173 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 6.743562e-01 | 0.171 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 6.749140e-01 | 0.171 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 6.749140e-01 | 0.171 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 6.749140e-01 | 0.171 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 6.749140e-01 | 0.171 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 6.749140e-01 | 0.171 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 6.749140e-01 | 0.171 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 6.749140e-01 | 0.171 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 6.774902e-01 | 0.169 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 6.804391e-01 | 0.167 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 6.804391e-01 | 0.167 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 6.804391e-01 | 0.167 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 6.804391e-01 | 0.167 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 6.824998e-01 | 0.166 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 6.848592e-01 | 0.164 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 6.881536e-01 | 0.162 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 6.881536e-01 | 0.162 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 6.881536e-01 | 0.162 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 6.881536e-01 | 0.162 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 6.881536e-01 | 0.162 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 6.881536e-01 | 0.162 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 6.934648e-01 | 0.159 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 6.961233e-01 | 0.157 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 6.961233e-01 | 0.157 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 6.961233e-01 | 0.157 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 6.961233e-01 | 0.157 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 6.963106e-01 | 0.157 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 6.963106e-01 | 0.157 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 6.978626e-01 | 0.156 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 6.978626e-01 | 0.156 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 6.978626e-01 | 0.156 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 6.978626e-01 | 0.156 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 6.992919e-01 | 0.155 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 7.005761e-01 | 0.155 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 7.017010e-01 | 0.154 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 7.017896e-01 | 0.154 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 7.017896e-01 | 0.154 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 7.017896e-01 | 0.154 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 7.017896e-01 | 0.154 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 7.017896e-01 | 0.154 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 7.017896e-01 | 0.154 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 7.017896e-01 | 0.154 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 7.017896e-01 | 0.154 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 7.017896e-01 | 0.154 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 7.017896e-01 | 0.154 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 7.017896e-01 | 0.154 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 7.058762e-01 | 0.151 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 7.058762e-01 | 0.151 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 7.058762e-01 | 0.151 | 0 | 0 |
| FGFR3b ligand binding and activation | R-HSA-190371 | 7.058762e-01 | 0.151 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis | R-HSA-9632974 | 7.058762e-01 | 0.151 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 7.058762e-01 | 0.151 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 7.058762e-01 | 0.151 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 7.058762e-01 | 0.151 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 7.058762e-01 | 0.151 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 7.058762e-01 | 0.151 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 7.058762e-01 | 0.151 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 7.058762e-01 | 0.151 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 7.058762e-01 | 0.151 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 7.058762e-01 | 0.151 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 7.058762e-01 | 0.151 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 7.061598e-01 | 0.151 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 7.097432e-01 | 0.149 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 7.097432e-01 | 0.149 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 7.097432e-01 | 0.149 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 7.103864e-01 | 0.149 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 7.105764e-01 | 0.148 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 7.117040e-01 | 0.148 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 7.146189e-01 | 0.146 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 7.146189e-01 | 0.146 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 7.146189e-01 | 0.146 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 7.146189e-01 | 0.146 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 7.146189e-01 | 0.146 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 7.146189e-01 | 0.146 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 7.200492e-01 | 0.143 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 7.200492e-01 | 0.143 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 7.200492e-01 | 0.143 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 7.248639e-01 | 0.140 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 7.248639e-01 | 0.140 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 7.248639e-01 | 0.140 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 7.267898e-01 | 0.139 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 7.267898e-01 | 0.139 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 7.267898e-01 | 0.139 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.267898e-01 | 0.139 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 7.267898e-01 | 0.139 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 7.267898e-01 | 0.139 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 7.292835e-01 | 0.137 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 7.301634e-01 | 0.137 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.301634e-01 | 0.137 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 7.307060e-01 | 0.136 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 7.339345e-01 | 0.134 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 7.358547e-01 | 0.133 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 7.363347e-01 | 0.133 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 7.375483e-01 | 0.132 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 7.375483e-01 | 0.132 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 7.375483e-01 | 0.132 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 7.375483e-01 | 0.132 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 7.380784e-01 | 0.132 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 7.394888e-01 | 0.131 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 7.397654e-01 | 0.131 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 7.397654e-01 | 0.131 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 7.397654e-01 | 0.131 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 7.397654e-01 | 0.131 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 7.397654e-01 | 0.131 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 7.397654e-01 | 0.131 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 7.397654e-01 | 0.131 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 7.397654e-01 | 0.131 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 7.397654e-01 | 0.131 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 7.411273e-01 | 0.130 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 7.411273e-01 | 0.130 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 7.411273e-01 | 0.130 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 7.411273e-01 | 0.130 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 7.461254e-01 | 0.127 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 7.466359e-01 | 0.127 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 7.486939e-01 | 0.126 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 7.494358e-01 | 0.125 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 7.499901e-01 | 0.125 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 7.542071e-01 | 0.123 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 7.542071e-01 | 0.123 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 7.549632e-01 | 0.122 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 7.549632e-01 | 0.122 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 7.549632e-01 | 0.122 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 7.558192e-01 | 0.122 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 7.675165e-01 | 0.115 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 7.675881e-01 | 0.115 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 7.675881e-01 | 0.115 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 7.675881e-01 | 0.115 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 7.675881e-01 | 0.115 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 7.697516e-01 | 0.114 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 7.697516e-01 | 0.114 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 7.697516e-01 | 0.114 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 7.697516e-01 | 0.114 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 7.697516e-01 | 0.114 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 7.697516e-01 | 0.114 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 7.697516e-01 | 0.114 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 7.697516e-01 | 0.114 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 7.697516e-01 | 0.114 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 7.697516e-01 | 0.114 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 7.700381e-01 | 0.113 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 7.700381e-01 | 0.113 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 7.714733e-01 | 0.113 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 7.714733e-01 | 0.113 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 7.714733e-01 | 0.113 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 7.714733e-01 | 0.113 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 7.714733e-01 | 0.113 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 7.714733e-01 | 0.113 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 7.714733e-01 | 0.113 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 7.714733e-01 | 0.113 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 7.749812e-01 | 0.111 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 7.758621e-01 | 0.110 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 7.809941e-01 | 0.107 | 0 | 0 |
| Immune System | R-HSA-168256 | 7.829776e-01 | 0.106 | 1 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 7.846530e-01 | 0.105 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 7.846530e-01 | 0.105 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 7.846530e-01 | 0.105 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 7.874477e-01 | 0.104 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 7.884343e-01 | 0.103 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 7.884343e-01 | 0.103 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 7.913269e-01 | 0.102 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 7.913269e-01 | 0.102 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 7.913269e-01 | 0.102 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 7.920474e-01 | 0.101 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 7.962842e-01 | 0.099 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 7.962842e-01 | 0.099 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 7.962842e-01 | 0.099 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 7.962842e-01 | 0.099 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 7.962842e-01 | 0.099 | 0 | 0 |
| Arachidonate production from DAG | R-HSA-426048 | 7.962842e-01 | 0.099 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 7.962842e-01 | 0.099 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 7.962842e-01 | 0.099 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 7.962842e-01 | 0.099 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 7.962842e-01 | 0.099 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 7.962842e-01 | 0.099 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 7.962842e-01 | 0.099 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 7.962842e-01 | 0.099 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 7.977632e-01 | 0.098 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 8.006669e-01 | 0.097 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 8.006669e-01 | 0.097 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 8.006669e-01 | 0.097 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 8.006669e-01 | 0.097 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 8.012524e-01 | 0.096 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.070287e-01 | 0.093 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 8.093606e-01 | 0.092 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 8.096411e-01 | 0.092 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 8.096411e-01 | 0.092 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.096411e-01 | 0.092 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 8.096411e-01 | 0.092 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 8.096411e-01 | 0.092 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 8.101755e-01 | 0.091 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 8.127390e-01 | 0.090 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 8.127390e-01 | 0.090 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 8.134490e-01 | 0.090 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 8.137415e-01 | 0.090 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 8.156691e-01 | 0.088 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 8.156691e-01 | 0.088 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 8.156691e-01 | 0.088 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 8.178156e-01 | 0.087 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 8.194100e-01 | 0.086 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 8.197606e-01 | 0.086 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 8.197606e-01 | 0.086 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 8.197606e-01 | 0.086 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 8.197606e-01 | 0.086 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 8.197606e-01 | 0.086 | 0 | 0 |
| Inorganic anion exchange by SLC26 transporters | R-HSA-427601 | 8.197606e-01 | 0.086 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 8.197606e-01 | 0.086 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 8.197606e-01 | 0.086 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 8.254459e-01 | 0.083 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 8.254459e-01 | 0.083 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 8.265071e-01 | 0.083 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 8.265071e-01 | 0.083 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 8.265071e-01 | 0.083 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 8.272727e-01 | 0.082 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 8.272727e-01 | 0.082 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.297011e-01 | 0.081 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 8.329221e-01 | 0.079 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 8.348908e-01 | 0.078 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.360385e-01 | 0.078 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 8.368346e-01 | 0.077 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 8.368439e-01 | 0.077 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 8.374295e-01 | 0.077 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 8.405328e-01 | 0.075 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 8.405328e-01 | 0.075 | 0 | 0 |
| Scavenging by Class H Receptors | R-HSA-3000497 | 8.405328e-01 | 0.075 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 8.405328e-01 | 0.075 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 8.405328e-01 | 0.075 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 8.405328e-01 | 0.075 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 8.405328e-01 | 0.075 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 8.417469e-01 | 0.075 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 8.420153e-01 | 0.075 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 8.450548e-01 | 0.073 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 8.465007e-01 | 0.072 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 8.479035e-01 | 0.072 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 8.486419e-01 | 0.071 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 8.513698e-01 | 0.070 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 8.523869e-01 | 0.069 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 8.545568e-01 | 0.068 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 8.545568e-01 | 0.068 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 8.550273e-01 | 0.068 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 8.550273e-01 | 0.068 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 8.562545e-01 | 0.067 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 8.562545e-01 | 0.067 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 8.562545e-01 | 0.067 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 8.563371e-01 | 0.067 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 8.563371e-01 | 0.067 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 8.589121e-01 | 0.066 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 8.589121e-01 | 0.066 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 8.589121e-01 | 0.066 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 8.589121e-01 | 0.066 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.589121e-01 | 0.066 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 8.589121e-01 | 0.066 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 8.589121e-01 | 0.066 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.589121e-01 | 0.066 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 8.589121e-01 | 0.066 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 8.589121e-01 | 0.066 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 8.589121e-01 | 0.066 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 8.589121e-01 | 0.066 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 8.589121e-01 | 0.066 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 8.589121e-01 | 0.066 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 8.589121e-01 | 0.066 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 8.593319e-01 | 0.066 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 8.627763e-01 | 0.064 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 8.656732e-01 | 0.063 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 8.658929e-01 | 0.063 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 8.661030e-01 | 0.062 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 8.661030e-01 | 0.062 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 8.693114e-01 | 0.061 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 8.693114e-01 | 0.061 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 8.723478e-01 | 0.059 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 8.723478e-01 | 0.059 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 8.723478e-01 | 0.059 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 8.751741e-01 | 0.058 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 8.751741e-01 | 0.058 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 8.751741e-01 | 0.058 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 8.751741e-01 | 0.058 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 8.751741e-01 | 0.058 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 8.751741e-01 | 0.058 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 8.751741e-01 | 0.058 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 8.769959e-01 | 0.057 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 8.769959e-01 | 0.057 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 8.769959e-01 | 0.057 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 8.786636e-01 | 0.056 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 8.786636e-01 | 0.056 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 8.786636e-01 | 0.056 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 8.799095e-01 | 0.056 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 8.800200e-01 | 0.056 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 8.812691e-01 | 0.055 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 8.812691e-01 | 0.055 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 8.812691e-01 | 0.055 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 8.835277e-01 | 0.054 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 8.842656e-01 | 0.053 | 1 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 8.868306e-01 | 0.052 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 8.869722e-01 | 0.052 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 8.874349e-01 | 0.052 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 8.895625e-01 | 0.051 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.895625e-01 | 0.051 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 8.895625e-01 | 0.051 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 8.895625e-01 | 0.051 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 8.895625e-01 | 0.051 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 8.895625e-01 | 0.051 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 8.922075e-01 | 0.050 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 8.922075e-01 | 0.050 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 8.922075e-01 | 0.050 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 8.922075e-01 | 0.050 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 8.922075e-01 | 0.050 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 8.922075e-01 | 0.050 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 8.937283e-01 | 0.049 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 8.959562e-01 | 0.048 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 8.959562e-01 | 0.048 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 9.000539e-01 | 0.046 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.000539e-01 | 0.046 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 9.001733e-01 | 0.046 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 9.001733e-01 | 0.046 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.001733e-01 | 0.046 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.022027e-01 | 0.045 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.022027e-01 | 0.045 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 9.022932e-01 | 0.045 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 9.022932e-01 | 0.045 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 9.022932e-01 | 0.045 | 0 | 0 |
| Dopamine clearance from the synaptic cleft | R-HSA-379401 | 9.022932e-01 | 0.045 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 9.022932e-01 | 0.045 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 9.053845e-01 | 0.043 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.105032e-01 | 0.041 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 9.113267e-01 | 0.040 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.113267e-01 | 0.040 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.113267e-01 | 0.040 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 9.113267e-01 | 0.040 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.115370e-01 | 0.040 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.126815e-01 | 0.040 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 9.135570e-01 | 0.039 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 9.135570e-01 | 0.039 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 9.135570e-01 | 0.039 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 9.135570e-01 | 0.039 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 9.135570e-01 | 0.039 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 9.135570e-01 | 0.039 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 9.135570e-01 | 0.039 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 9.135570e-01 | 0.039 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 9.135570e-01 | 0.039 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 9.152978e-01 | 0.038 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.157009e-01 | 0.038 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.159060e-01 | 0.038 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.176736e-01 | 0.037 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.176736e-01 | 0.037 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.194886e-01 | 0.036 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 9.194886e-01 | 0.036 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 9.194886e-01 | 0.036 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.194886e-01 | 0.036 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.196475e-01 | 0.036 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.196475e-01 | 0.036 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.196475e-01 | 0.036 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.198878e-01 | 0.036 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 9.198878e-01 | 0.036 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 9.201098e-01 | 0.036 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 9.201098e-01 | 0.036 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 9.208641e-01 | 0.036 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.234314e-01 | 0.035 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 9.235228e-01 | 0.035 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.235228e-01 | 0.035 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.235228e-01 | 0.035 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 9.235228e-01 | 0.035 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 9.235228e-01 | 0.035 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 9.235228e-01 | 0.035 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 9.235228e-01 | 0.035 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 9.235228e-01 | 0.035 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 9.235228e-01 | 0.035 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 9.255681e-01 | 0.034 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 9.261815e-01 | 0.033 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 9.261815e-01 | 0.033 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 9.272290e-01 | 0.033 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.283235e-01 | 0.032 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.323403e-01 | 0.030 | 0 | 0 |
| Catecholamine biosynthesis | R-HSA-209905 | 9.323403e-01 | 0.030 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 9.323403e-01 | 0.030 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 9.323403e-01 | 0.030 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 9.323403e-01 | 0.030 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 9.330571e-01 | 0.030 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 9.330571e-01 | 0.030 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.341310e-01 | 0.030 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.341310e-01 | 0.030 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 9.346819e-01 | 0.029 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 9.386171e-01 | 0.028 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 9.401416e-01 | 0.027 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.404094e-01 | 0.027 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.433109e-01 | 0.025 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.433109e-01 | 0.025 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 9.456190e-01 | 0.024 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.461162e-01 | 0.024 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 9.461162e-01 | 0.024 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.467895e-01 | 0.024 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 9.470437e-01 | 0.024 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 9.470437e-01 | 0.024 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 9.470437e-01 | 0.024 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 9.470437e-01 | 0.024 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 9.470437e-01 | 0.024 | 0 | 0 |
| Methionine salvage pathway | R-HSA-1237112 | 9.470437e-01 | 0.024 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 9.470437e-01 | 0.024 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 9.470437e-01 | 0.024 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 9.470437e-01 | 0.024 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.487466e-01 | 0.023 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.488204e-01 | 0.023 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.506588e-01 | 0.022 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 9.511025e-01 | 0.022 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 9.512997e-01 | 0.022 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.525959e-01 | 0.021 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.527792e-01 | 0.021 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 9.531504e-01 | 0.021 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.531504e-01 | 0.021 | 0 | 0 |
| Keratan sulfate degradation | R-HSA-2022857 | 9.531504e-01 | 0.021 | 0 | 0 |
| Melanin biosynthesis | R-HSA-5662702 | 9.531504e-01 | 0.021 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 9.531504e-01 | 0.021 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 9.535150e-01 | 0.021 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.560046e-01 | 0.020 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.560046e-01 | 0.020 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.565178e-01 | 0.019 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.565178e-01 | 0.019 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 9.585532e-01 | 0.018 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 9.585532e-01 | 0.018 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.585532e-01 | 0.018 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 9.585532e-01 | 0.018 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 9.585532e-01 | 0.018 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.602725e-01 | 0.018 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.602725e-01 | 0.018 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.602725e-01 | 0.018 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.602725e-01 | 0.018 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.604441e-01 | 0.018 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.604441e-01 | 0.018 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.607345e-01 | 0.017 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.611319e-01 | 0.017 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.631878e-01 | 0.016 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 9.631878e-01 | 0.016 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 9.632599e-01 | 0.016 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 9.633332e-01 | 0.016 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 9.633332e-01 | 0.016 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 9.633332e-01 | 0.016 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.633332e-01 | 0.016 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 9.633332e-01 | 0.016 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.657193e-01 | 0.015 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.661541e-01 | 0.015 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.662230e-01 | 0.015 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 9.667590e-01 | 0.015 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 9.675622e-01 | 0.014 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 9.675622e-01 | 0.014 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.675622e-01 | 0.014 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.675622e-01 | 0.014 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.675622e-01 | 0.014 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 9.675622e-01 | 0.014 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 9.676466e-01 | 0.014 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.676466e-01 | 0.014 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.676466e-01 | 0.014 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 9.678755e-01 | 0.014 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.694167e-01 | 0.013 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.708206e-01 | 0.013 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 9.708206e-01 | 0.013 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.708206e-01 | 0.013 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.708206e-01 | 0.013 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 9.709411e-01 | 0.013 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.713036e-01 | 0.013 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.713036e-01 | 0.013 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.714304e-01 | 0.013 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.726189e-01 | 0.012 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.736931e-01 | 0.012 | 0 | 0 |
| Depurination | R-HSA-73927 | 9.736931e-01 | 0.012 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.738880e-01 | 0.011 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.746137e-01 | 0.011 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 9.746137e-01 | 0.011 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 9.746137e-01 | 0.011 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.746137e-01 | 0.011 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.746137e-01 | 0.011 | 0 | 0 |
| Cytosolic sulfonation of small molecules | R-HSA-156584 | 9.750533e-01 | 0.011 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.750533e-01 | 0.011 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.762913e-01 | 0.010 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.775422e-01 | 0.010 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.775422e-01 | 0.010 | 0 | 0 |
| Retinoid cycle disease events | R-HSA-2453864 | 9.775422e-01 | 0.010 | 0 | 0 |
| Diseases associated with visual transduction | R-HSA-2474795 | 9.775422e-01 | 0.010 | 0 | 0 |
| Diseases of the neuronal system | R-HSA-9675143 | 9.775422e-01 | 0.010 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.775422e-01 | 0.010 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.775422e-01 | 0.010 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.790650e-01 | 0.009 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.790650e-01 | 0.009 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.801330e-01 | 0.009 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 9.801330e-01 | 0.009 | 0 | 0 |
| Linoleic acid (LA) metabolism | R-HSA-2046105 | 9.801330e-01 | 0.009 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 9.801330e-01 | 0.009 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.807632e-01 | 0.008 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.807632e-01 | 0.008 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.811809e-01 | 0.008 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.814453e-01 | 0.008 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 9.824250e-01 | 0.008 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 9.824250e-01 | 0.008 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.824250e-01 | 0.008 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 9.824250e-01 | 0.008 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.824250e-01 | 0.008 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 9.824250e-01 | 0.008 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.844119e-01 | 0.007 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.844119e-01 | 0.007 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.844119e-01 | 0.007 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.844527e-01 | 0.007 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.844527e-01 | 0.007 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 9.857508e-01 | 0.006 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.859743e-01 | 0.006 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.862466e-01 | 0.006 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.862466e-01 | 0.006 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.862466e-01 | 0.006 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.869615e-01 | 0.006 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.873615e-01 | 0.006 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.876884e-01 | 0.005 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.883271e-01 | 0.005 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.883972e-01 | 0.005 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.886549e-01 | 0.005 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.892376e-01 | 0.005 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.892376e-01 | 0.005 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.893313e-01 | 0.005 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.894020e-01 | 0.005 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.898007e-01 | 0.004 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.900563e-01 | 0.004 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.900563e-01 | 0.004 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 9.904796e-01 | 0.004 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.904796e-01 | 0.004 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.904883e-01 | 0.004 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.908333e-01 | 0.004 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.908934e-01 | 0.004 | 0 | 0 |
| Keratan sulfate biosynthesis | R-HSA-2022854 | 9.915783e-01 | 0.004 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.915783e-01 | 0.004 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.917634e-01 | 0.004 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.925503e-01 | 0.003 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.925503e-01 | 0.003 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.930919e-01 | 0.003 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.932232e-01 | 0.003 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.941047e-01 | 0.003 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.941709e-01 | 0.003 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.946524e-01 | 0.002 | 1 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.946594e-01 | 0.002 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.946749e-01 | 0.002 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.947173e-01 | 0.002 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.947392e-01 | 0.002 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.948438e-01 | 0.002 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.948438e-01 | 0.002 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.951205e-01 | 0.002 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.951933e-01 | 0.002 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.954390e-01 | 0.002 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.954390e-01 | 0.002 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.954972e-01 | 0.002 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.959656e-01 | 0.002 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.959656e-01 | 0.002 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.959656e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.964314e-01 | 0.002 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.965706e-01 | 0.001 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.967683e-01 | 0.001 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.967683e-01 | 0.001 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.968434e-01 | 0.001 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.968434e-01 | 0.001 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.971301e-01 | 0.001 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.971350e-01 | 0.001 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.972079e-01 | 0.001 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.973840e-01 | 0.001 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.974992e-01 | 0.001 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.975303e-01 | 0.001 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.977588e-01 | 0.001 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.977690e-01 | 0.001 | 1 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.979426e-01 | 0.001 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.979917e-01 | 0.001 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.979917e-01 | 0.001 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.979917e-01 | 0.001 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.980678e-01 | 0.001 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.981704e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.982308e-01 | 0.001 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.982308e-01 | 0.001 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.983681e-01 | 0.001 | 0 | 0 |
| The canonical retinoid cycle in rods (twilight vision) | R-HSA-2453902 | 9.984884e-01 | 0.001 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.984884e-01 | 0.001 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.985567e-01 | 0.001 | 0 | 0 |
| Translation | R-HSA-72766 | 9.986041e-01 | 0.001 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.986846e-01 | 0.001 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.987262e-01 | 0.001 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.988174e-01 | 0.001 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.988861e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.989541e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.989642e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.990365e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.990729e-01 | 0.000 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.990729e-01 | 0.000 | 0 | 0 |
| Keratan sulfate/keratin metabolism | R-HSA-1638074 | 9.990749e-01 | 0.000 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.990749e-01 | 0.000 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.991818e-01 | 0.000 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.992577e-01 | 0.000 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.992763e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.992891e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.993359e-01 | 0.000 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.993359e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.993359e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.994059e-01 | 0.000 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.995249e-01 | 0.000 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.995412e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.995751e-01 | 0.000 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.996084e-01 | 0.000 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.996605e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.997291e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.997543e-01 | 0.000 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.997604e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.997834e-01 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.997906e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.998042e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.998499e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.998534e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.998627e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.998901e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.998901e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.998945e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.998986e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999007e-01 | 0.000 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.999018e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.999099e-01 | 0.000 | 1 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.999299e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.999380e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.999380e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999413e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.999452e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.999504e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.999515e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.999515e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999686e-01 | 0.000 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.999738e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999794e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999819e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999875e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999900e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999921e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999928e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999932e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999937e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999965e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999974e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.999975e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999982e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999986e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999987e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999988e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999988e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999989e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999999e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999999e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 1.000000e+00 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 1.000000e+00 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 1.000000e+00 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 1 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 1.110223e-16 | 15.955 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.110223e-16 | 15.955 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 3.330669e-16 | 15.477 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 4.440892e-16 | 15.353 | 1 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.665335e-15 | 14.778 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 3.441691e-15 | 14.463 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 8.548717e-15 | 14.068 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 7.360779e-14 | 13.133 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 1.030287e-13 | 12.987 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 7.498446e-13 | 12.125 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 2.109868e-12 | 11.676 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.332112e-11 | 10.875 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 1.930633e-11 | 10.714 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 4.501255e-11 | 10.347 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 8.203638e-11 | 10.086 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 1.004451e-10 | 9.998 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 1.029291e-10 | 9.987 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.434504e-10 | 9.843 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.779444e-10 | 9.750 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 3.294847e-10 | 9.482 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 3.580162e-10 | 9.446 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 4.879473e-10 | 9.312 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 7.032298e-10 | 9.153 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 8.455857e-10 | 9.073 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.023837e-09 | 8.990 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 1.037818e-09 | 8.984 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.131570e-09 | 8.946 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 1.268048e-09 | 8.897 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.282491e-09 | 8.892 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 1.848260e-09 | 8.733 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.524729e-09 | 8.598 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.260613e-09 | 8.279 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 5.727677e-09 | 8.242 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 5.595427e-09 | 8.252 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 5.859225e-09 | 8.232 | 0 | 0 |
| Kinesins | R-HSA-983189 | 6.467955e-09 | 8.189 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.111026e-08 | 7.954 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.428047e-08 | 7.845 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 1.924930e-08 | 7.716 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 2.601204e-08 | 7.585 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 2.601204e-08 | 7.585 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 2.734694e-08 | 7.563 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 3.162111e-08 | 7.500 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 3.098186e-08 | 7.509 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 3.879355e-08 | 7.411 | 1 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 4.267955e-08 | 7.370 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 4.673202e-08 | 7.330 | 1 | 0 |
| Axon guidance | R-HSA-422475 | 4.887854e-08 | 7.311 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 5.534651e-08 | 7.257 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 6.711135e-08 | 7.173 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 7.199210e-08 | 7.143 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.035330e-07 | 6.985 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.035744e-07 | 6.985 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.115502e-07 | 6.953 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.090515e-07 | 6.962 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.107483e-07 | 6.956 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.131856e-07 | 6.946 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 1.800722e-07 | 6.745 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.868576e-07 | 6.728 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 1.960345e-07 | 6.708 | 1 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 1.962296e-07 | 6.707 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 2.118247e-07 | 6.674 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 2.270875e-07 | 6.644 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 2.426733e-07 | 6.615 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 2.440339e-07 | 6.613 | 1 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.672787e-07 | 6.573 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 2.819864e-07 | 6.550 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.734292e-07 | 6.563 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.837023e-07 | 6.547 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 2.854621e-07 | 6.544 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 3.074269e-07 | 6.512 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 3.074269e-07 | 6.512 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 3.441030e-07 | 6.463 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 3.597305e-07 | 6.444 | 1 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 5.037153e-07 | 6.298 | 1 | 1 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 5.812438e-07 | 6.236 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 6.717048e-07 | 6.173 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 7.054498e-07 | 6.152 | 1 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 7.457484e-07 | 6.127 | 1 | 1 |
| Programmed Cell Death | R-HSA-5357801 | 7.182600e-07 | 6.144 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 8.085511e-07 | 6.092 | 1 | 0 |
| Protein folding | R-HSA-391251 | 8.128964e-07 | 6.090 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 9.375508e-07 | 6.028 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 9.797416e-07 | 6.009 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.072867e-06 | 5.969 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 1.144961e-06 | 5.941 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.434022e-06 | 5.843 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.692654e-06 | 5.771 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.774830e-06 | 5.751 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.976406e-06 | 5.704 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.119459e-06 | 5.674 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 2.308205e-06 | 5.637 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 3.465310e-06 | 5.460 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 3.465310e-06 | 5.460 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 4.443168e-06 | 5.352 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 5.469087e-06 | 5.262 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 6.130009e-06 | 5.213 | 1 | 1 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 5.903854e-06 | 5.229 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 5.903854e-06 | 5.229 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 5.848925e-06 | 5.233 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 6.723759e-06 | 5.172 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 7.214060e-06 | 5.142 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 7.569962e-06 | 5.121 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.109241e-05 | 4.955 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.204313e-05 | 4.919 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.204313e-05 | 4.919 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.348099e-05 | 4.870 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 1.386400e-05 | 4.858 | 1 | 1 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 1.394727e-05 | 4.856 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.422727e-05 | 4.847 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 1.462031e-05 | 4.835 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 2.073816e-05 | 4.683 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 2.541626e-05 | 4.595 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 2.548970e-05 | 4.594 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 3.218088e-05 | 4.492 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 3.844465e-05 | 4.415 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 4.150438e-05 | 4.382 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 4.150438e-05 | 4.382 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 4.300434e-05 | 4.366 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 4.403335e-05 | 4.356 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 4.508431e-05 | 4.346 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 4.547664e-05 | 4.342 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 4.736896e-05 | 4.325 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 4.906681e-05 | 4.309 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 5.391474e-05 | 4.268 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 5.020641e-05 | 4.299 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 5.908968e-05 | 4.228 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 5.908968e-05 | 4.228 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 5.909766e-05 | 4.228 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 5.934405e-05 | 4.227 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 6.545407e-05 | 4.184 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 6.800596e-05 | 4.167 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 8.129858e-05 | 4.090 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 8.129858e-05 | 4.090 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 7.785427e-05 | 4.109 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 8.141710e-05 | 4.089 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 8.311865e-05 | 4.080 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 9.456855e-05 | 4.024 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 9.796729e-05 | 4.009 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 1.071314e-04 | 3.970 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 1.123696e-04 | 3.949 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.147143e-04 | 3.940 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 1.270818e-04 | 3.896 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.284524e-04 | 3.891 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.284524e-04 | 3.891 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.473544e-04 | 3.832 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 1.632537e-04 | 3.787 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.704702e-04 | 3.768 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.989099e-04 | 3.701 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.989099e-04 | 3.701 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 2.004294e-04 | 3.698 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.058056e-04 | 3.687 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.058056e-04 | 3.687 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.099686e-04 | 3.678 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 2.259785e-04 | 3.646 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 2.434211e-04 | 3.614 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 2.434211e-04 | 3.614 | 1 | 1 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 2.654779e-04 | 3.576 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 2.603786e-04 | 3.584 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 2.675850e-04 | 3.573 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 2.654779e-04 | 3.576 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 2.940885e-04 | 3.532 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 3.158142e-04 | 3.501 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 3.195920e-04 | 3.495 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 3.275224e-04 | 3.485 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 3.275224e-04 | 3.485 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 3.317022e-04 | 3.479 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 3.334277e-04 | 3.477 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 3.334277e-04 | 3.477 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 3.489038e-04 | 3.457 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 3.694191e-04 | 3.432 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 3.818237e-04 | 3.418 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 3.924998e-04 | 3.406 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 3.924998e-04 | 3.406 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 4.034848e-04 | 3.394 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 4.182699e-04 | 3.379 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 4.313596e-04 | 3.365 | 0 | 0 |
| S Phase | R-HSA-69242 | 4.302554e-04 | 3.366 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 4.774035e-04 | 3.321 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 5.087639e-04 | 3.293 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 5.137210e-04 | 3.289 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 5.159949e-04 | 3.287 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 5.170769e-04 | 3.286 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 5.262936e-04 | 3.279 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 5.289999e-04 | 3.277 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 5.419428e-04 | 3.266 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 5.675601e-04 | 3.246 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 5.772697e-04 | 3.239 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 5.772697e-04 | 3.239 | 0 | 0 |
| Immune System | R-HSA-168256 | 5.852873e-04 | 3.233 | 1 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 6.307091e-04 | 3.200 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 6.941126e-04 | 3.159 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 7.061075e-04 | 3.151 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 7.075317e-04 | 3.150 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 7.309514e-04 | 3.136 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 7.309514e-04 | 3.136 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 7.391560e-04 | 3.131 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 7.391560e-04 | 3.131 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 7.516325e-04 | 3.124 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 7.629509e-04 | 3.118 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 7.690744e-04 | 3.114 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 8.003214e-04 | 3.097 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 8.713696e-04 | 3.060 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 1.008047e-03 | 2.997 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 8.980022e-04 | 3.047 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 8.980022e-04 | 3.047 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 1.015272e-03 | 2.993 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.121827e-03 | 2.950 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 1.142202e-03 | 2.942 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.169336e-03 | 2.932 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.169336e-03 | 2.932 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 1.171864e-03 | 2.931 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 1.185197e-03 | 2.926 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.185932e-03 | 2.926 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.241778e-03 | 2.906 | 1 | 1 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.396850e-03 | 2.855 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.561282e-03 | 2.807 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.692790e-03 | 2.771 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.735970e-03 | 2.760 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 1.746219e-03 | 2.758 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 1.746219e-03 | 2.758 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 1.746219e-03 | 2.758 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.828947e-03 | 2.738 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.880514e-03 | 2.726 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 1.890342e-03 | 2.723 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 2.124314e-03 | 2.673 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.194818e-03 | 2.659 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.194818e-03 | 2.659 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.194818e-03 | 2.659 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 1.907106e-03 | 2.720 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 2.164681e-03 | 2.665 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.194818e-03 | 2.659 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 2.207813e-03 | 2.656 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 1.927402e-03 | 2.715 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.983421e-03 | 2.703 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 2.010444e-03 | 2.697 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 2.194818e-03 | 2.659 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 2.010444e-03 | 2.697 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 2.228462e-03 | 2.652 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.259393e-03 | 2.646 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 2.282682e-03 | 2.642 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 2.291575e-03 | 2.640 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 2.401109e-03 | 2.620 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 2.401109e-03 | 2.620 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 2.428217e-03 | 2.615 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 2.428217e-03 | 2.615 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 2.565646e-03 | 2.591 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 2.611777e-03 | 2.583 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 2.611777e-03 | 2.583 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 2.649809e-03 | 2.577 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.682110e-03 | 2.572 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 2.685100e-03 | 2.571 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 2.690485e-03 | 2.570 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 2.906756e-03 | 2.537 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 2.958111e-03 | 2.529 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 3.046628e-03 | 2.516 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 3.151450e-03 | 2.501 | 0 | 0 |
| Translation | R-HSA-72766 | 3.220011e-03 | 2.492 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 3.225375e-03 | 2.491 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 3.225375e-03 | 2.491 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 3.315938e-03 | 2.479 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 3.344132e-03 | 2.476 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 3.365922e-03 | 2.473 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 3.414132e-03 | 2.467 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 3.444524e-03 | 2.463 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 3.444524e-03 | 2.463 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 3.508813e-03 | 2.455 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 3.508813e-03 | 2.455 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 3.537851e-03 | 2.451 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 3.565198e-03 | 2.448 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 3.615205e-03 | 2.442 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 3.750576e-03 | 2.426 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 3.990233e-03 | 2.399 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 4.233014e-03 | 2.373 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 4.058267e-03 | 2.392 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 4.156392e-03 | 2.381 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 4.289214e-03 | 2.368 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 4.658697e-03 | 2.332 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 4.243958e-03 | 2.372 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 4.499624e-03 | 2.347 | 1 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 4.692529e-03 | 2.329 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 4.692529e-03 | 2.329 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 4.692529e-03 | 2.329 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 4.692529e-03 | 2.329 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 4.692529e-03 | 2.329 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 4.692529e-03 | 2.329 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 4.692529e-03 | 2.329 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 4.692529e-03 | 2.329 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 4.692529e-03 | 2.329 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 4.692529e-03 | 2.329 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 4.692529e-03 | 2.329 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 4.692529e-03 | 2.329 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 4.695202e-03 | 2.328 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 4.695202e-03 | 2.328 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 4.695202e-03 | 2.328 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 4.695202e-03 | 2.328 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 4.842511e-03 | 2.315 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 4.897428e-03 | 2.310 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 4.897428e-03 | 2.310 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 4.897428e-03 | 2.310 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 4.897428e-03 | 2.310 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 4.911622e-03 | 2.309 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 5.009102e-03 | 2.300 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 5.009102e-03 | 2.300 | 1 | 1 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 5.165040e-03 | 2.287 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 5.174944e-03 | 2.286 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 5.324013e-03 | 2.274 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 5.401178e-03 | 2.268 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 5.401178e-03 | 2.268 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 5.465351e-03 | 2.262 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 5.482294e-03 | 2.261 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 5.482294e-03 | 2.261 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 5.482294e-03 | 2.261 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.557338e-03 | 2.255 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 5.587448e-03 | 2.253 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 5.678076e-03 | 2.246 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 5.802624e-03 | 2.236 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 6.170245e-03 | 2.210 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 6.170245e-03 | 2.210 | 1 | 1 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 6.257599e-03 | 2.204 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 6.535512e-03 | 2.185 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 6.765518e-03 | 2.170 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 6.884650e-03 | 2.162 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 6.884650e-03 | 2.162 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 8.625867e-03 | 2.064 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 8.007393e-03 | 2.097 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 8.458264e-03 | 2.073 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 9.264267e-03 | 2.033 | 1 | 1 |
| MAP2K and MAPK activation | R-HSA-5674135 | 8.668122e-03 | 2.062 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 9.264267e-03 | 2.033 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 8.458264e-03 | 2.073 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 8.768139e-03 | 2.057 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 7.499298e-03 | 2.125 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 8.720369e-03 | 2.059 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 8.191766e-03 | 2.087 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 8.795238e-03 | 2.056 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 8.007393e-03 | 2.097 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 7.955266e-03 | 2.099 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 8.684736e-03 | 2.061 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 9.277113e-03 | 2.033 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 8.118045e-03 | 2.091 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 9.557196e-03 | 2.020 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 9.557196e-03 | 2.020 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 9.901936e-03 | 2.004 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.008222e-02 | 1.996 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.008222e-02 | 1.996 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.012149e-02 | 1.995 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.073948e-02 | 1.969 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.077036e-02 | 1.968 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.077036e-02 | 1.968 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 1.098232e-02 | 1.959 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 1.120542e-02 | 1.951 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.124537e-02 | 1.949 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 1.133067e-02 | 1.946 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 1.191952e-02 | 1.924 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.192161e-02 | 1.924 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 1.221842e-02 | 1.913 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.222269e-02 | 1.913 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.222269e-02 | 1.913 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 1.256512e-02 | 1.901 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.274515e-02 | 1.895 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 1.274515e-02 | 1.895 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 1.291335e-02 | 1.889 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 1.305375e-02 | 1.884 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 1.305375e-02 | 1.884 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.313999e-02 | 1.881 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 1.313999e-02 | 1.881 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 1.349047e-02 | 1.870 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 1.349047e-02 | 1.870 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 1.384811e-02 | 1.859 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 1.384811e-02 | 1.859 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.384811e-02 | 1.859 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 1.384811e-02 | 1.859 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 1.386496e-02 | 1.858 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 1.392382e-02 | 1.856 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.409565e-02 | 1.851 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 1.422434e-02 | 1.847 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.422434e-02 | 1.847 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 1.422434e-02 | 1.847 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 1.468284e-02 | 1.833 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 1.479267e-02 | 1.830 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.523414e-02 | 1.817 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 1.529156e-02 | 1.816 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.582290e-02 | 1.801 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 1.585215e-02 | 1.800 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.591161e-02 | 1.798 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 1.601563e-02 | 1.795 | 1 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.601618e-02 | 1.795 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 1.601618e-02 | 1.795 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 1.611204e-02 | 1.793 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.623084e-02 | 1.790 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 1.623084e-02 | 1.790 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 2.195165e-02 | 1.659 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.195165e-02 | 1.659 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 2.195165e-02 | 1.659 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 2.195165e-02 | 1.659 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 2.138383e-02 | 1.670 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 2.138383e-02 | 1.670 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 1.969782e-02 | 1.706 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.951297e-02 | 1.710 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 2.221141e-02 | 1.653 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.729436e-02 | 1.762 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 1.714213e-02 | 1.766 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 2.015193e-02 | 1.696 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 1.679910e-02 | 1.775 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 1.840342e-02 | 1.735 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 1.789127e-02 | 1.747 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 2.195165e-02 | 1.659 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 1.789232e-02 | 1.747 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 2.015193e-02 | 1.696 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.840342e-02 | 1.735 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 1.944185e-02 | 1.711 | 1 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.729436e-02 | 1.762 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 1.729436e-02 | 1.762 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 1.840342e-02 | 1.735 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 1.846644e-02 | 1.734 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 2.221141e-02 | 1.653 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.679910e-02 | 1.775 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 2.015193e-02 | 1.696 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.729436e-02 | 1.762 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 1.892837e-02 | 1.723 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 2.195165e-02 | 1.659 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 2.014873e-02 | 1.696 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.942299e-02 | 1.712 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 2.244411e-02 | 1.649 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 2.244411e-02 | 1.649 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 2.244411e-02 | 1.649 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 2.246543e-02 | 1.648 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 2.261047e-02 | 1.646 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 2.306510e-02 | 1.637 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 2.306510e-02 | 1.637 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 2.337171e-02 | 1.631 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 2.424276e-02 | 1.615 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 2.506536e-02 | 1.601 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 2.506536e-02 | 1.601 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 2.538726e-02 | 1.595 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 2.588207e-02 | 1.587 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.605466e-02 | 1.584 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.605466e-02 | 1.584 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 2.605466e-02 | 1.584 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 2.605466e-02 | 1.584 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.625089e-02 | 1.581 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 2.636964e-02 | 1.579 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 2.656706e-02 | 1.576 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 2.656706e-02 | 1.576 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 2.656706e-02 | 1.576 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.677311e-02 | 1.572 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 2.686506e-02 | 1.571 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 2.717309e-02 | 1.566 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 2.719073e-02 | 1.566 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 2.720593e-02 | 1.565 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.814691e-02 | 1.551 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 2.815765e-02 | 1.550 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 2.815765e-02 | 1.550 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 2.822795e-02 | 1.549 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 2.859317e-02 | 1.544 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 2.878698e-02 | 1.541 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.950314e-02 | 1.530 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 2.998257e-02 | 1.523 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 2.998257e-02 | 1.523 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 3.003777e-02 | 1.522 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 3.003777e-02 | 1.522 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 3.053141e-02 | 1.515 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 3.079099e-02 | 1.512 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 3.166534e-02 | 1.499 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 3.175845e-02 | 1.498 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 3.201733e-02 | 1.495 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 3.205988e-02 | 1.494 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 3.221337e-02 | 1.492 | 1 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 3.290547e-02 | 1.483 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 3.295373e-02 | 1.482 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 3.295373e-02 | 1.482 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 3.391670e-02 | 1.470 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 3.391670e-02 | 1.470 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 3.435670e-02 | 1.464 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 3.459651e-02 | 1.461 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 3.459651e-02 | 1.461 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 3.459651e-02 | 1.461 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 3.524415e-02 | 1.453 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 3.526978e-02 | 1.453 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 3.580722e-02 | 1.446 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 3.612523e-02 | 1.442 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 3.612523e-02 | 1.442 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 3.622822e-02 | 1.441 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 3.639358e-02 | 1.439 | 1 | 0 |
| Activation of RAC1 | R-HSA-428540 | 3.716649e-02 | 1.430 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 3.840729e-02 | 1.416 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 3.927251e-02 | 1.406 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 3.950251e-02 | 1.403 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 3.950251e-02 | 1.403 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 3.957937e-02 | 1.403 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 3.983925e-02 | 1.400 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 4.078894e-02 | 1.389 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 4.198238e-02 | 1.377 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 4.390026e-02 | 1.358 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 5.116907e-02 | 1.291 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 5.116907e-02 | 1.291 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 5.116907e-02 | 1.291 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 5.116907e-02 | 1.291 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 4.518480e-02 | 1.345 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 5.409165e-02 | 1.267 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 4.393081e-02 | 1.357 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 5.093147e-02 | 1.293 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 5.208189e-02 | 1.283 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 4.416291e-02 | 1.355 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 4.309063e-02 | 1.366 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 5.256558e-02 | 1.279 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 5.256558e-02 | 1.279 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 4.878431e-02 | 1.312 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 4.878431e-02 | 1.312 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 4.656764e-02 | 1.332 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 5.208189e-02 | 1.283 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 5.370861e-02 | 1.270 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 4.331252e-02 | 1.363 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 5.208189e-02 | 1.283 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 4.309063e-02 | 1.366 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 5.409165e-02 | 1.267 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 5.036197e-02 | 1.298 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 5.036197e-02 | 1.298 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 5.168642e-02 | 1.287 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 4.915032e-02 | 1.308 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 5.924390e-02 | 1.227 | 1 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 4.570750e-02 | 1.340 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 6.266924e-02 | 1.203 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 5.552968e-02 | 1.255 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 4.518480e-02 | 1.345 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 5.764230e-02 | 1.239 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 6.387692e-02 | 1.195 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 5.861807e-02 | 1.232 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 5.431789e-02 | 1.265 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 5.093147e-02 | 1.293 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 5.093147e-02 | 1.293 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 4.601108e-02 | 1.337 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 4.878431e-02 | 1.312 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 6.320259e-02 | 1.199 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 4.416291e-02 | 1.355 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 5.093147e-02 | 1.293 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 5.264197e-02 | 1.279 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 5.370861e-02 | 1.270 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 5.116907e-02 | 1.291 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 5.099050e-02 | 1.293 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 5.664317e-02 | 1.247 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 5.437060e-02 | 1.265 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 4.372305e-02 | 1.359 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 4.331252e-02 | 1.363 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 4.518480e-02 | 1.345 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 4.518480e-02 | 1.345 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 4.393081e-02 | 1.357 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 6.266924e-02 | 1.203 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 6.166691e-02 | 1.210 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 6.377197e-02 | 1.195 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 5.845755e-02 | 1.233 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 4.570750e-02 | 1.340 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 5.664317e-02 | 1.247 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 4.518480e-02 | 1.345 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 4.518480e-02 | 1.345 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 6.387692e-02 | 1.195 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 4.309063e-02 | 1.366 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.663515e-02 | 1.331 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 4.331252e-02 | 1.363 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 5.838779e-02 | 1.234 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 5.861807e-02 | 1.232 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 5.854756e-02 | 1.232 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 6.420613e-02 | 1.192 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 6.420613e-02 | 1.192 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 6.420613e-02 | 1.192 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 6.448192e-02 | 1.191 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 6.503713e-02 | 1.187 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 6.503713e-02 | 1.187 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 6.503713e-02 | 1.187 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 6.503713e-02 | 1.187 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 6.503713e-02 | 1.187 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 6.562202e-02 | 1.183 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 6.562202e-02 | 1.183 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 6.562202e-02 | 1.183 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 6.562202e-02 | 1.183 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 6.638829e-02 | 1.178 | 1 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 6.677813e-02 | 1.175 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 6.677813e-02 | 1.175 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 6.677813e-02 | 1.175 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 6.677813e-02 | 1.175 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 6.775253e-02 | 1.169 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 6.775253e-02 | 1.169 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 6.907102e-02 | 1.161 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 6.907102e-02 | 1.161 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 7.026287e-02 | 1.153 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 7.033650e-02 | 1.153 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 7.073644e-02 | 1.150 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 7.250841e-02 | 1.140 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 7.309383e-02 | 1.136 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 7.309383e-02 | 1.136 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 7.330117e-02 | 1.135 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 7.330117e-02 | 1.135 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 7.452234e-02 | 1.128 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 7.561813e-02 | 1.121 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 7.561813e-02 | 1.121 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 7.561813e-02 | 1.121 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 7.561813e-02 | 1.121 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 7.561813e-02 | 1.121 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 7.584934e-02 | 1.120 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 7.584934e-02 | 1.120 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 7.650512e-02 | 1.116 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 7.650512e-02 | 1.116 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 7.650512e-02 | 1.116 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 7.650512e-02 | 1.116 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 7.860665e-02 | 1.105 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 7.860665e-02 | 1.105 | 0 | 0 |
| Drug resistance of FLT3 mutants | R-HSA-9702506 | 7.927684e-02 | 1.101 | 0 | 0 |
| FLT3 mutants bind TKIs | R-HSA-9702509 | 7.927684e-02 | 1.101 | 0 | 0 |
| gilteritinib-resistant FLT3 mutants | R-HSA-9702590 | 7.927684e-02 | 1.101 | 0 | 0 |
| quizartinib-resistant FLT3 mutants | R-HSA-9702620 | 7.927684e-02 | 1.101 | 0 | 0 |
| tamatinib-resistant FLT3 mutants | R-HSA-9703009 | 7.927684e-02 | 1.101 | 0 | 0 |
| semaxanib-resistant FLT3 mutants | R-HSA-9702577 | 7.927684e-02 | 1.101 | 0 | 0 |
| lestaurtinib-resistant FLT3 mutants | R-HSA-9702596 | 7.927684e-02 | 1.101 | 0 | 0 |
| KW2449-resistant FLT3 mutants | R-HSA-9702569 | 7.927684e-02 | 1.101 | 0 | 0 |
| sorafenib-resistant FLT3 mutants | R-HSA-9702624 | 7.927684e-02 | 1.101 | 0 | 0 |
| pexidartinib-resistant FLT3 mutants | R-HSA-9702605 | 7.927684e-02 | 1.101 | 0 | 0 |
| tandutinib-resistant FLT3 mutants | R-HSA-9702636 | 7.927684e-02 | 1.101 | 0 | 0 |
| crenolanib-resistant FLT3 mutants | R-HSA-9702581 | 7.927684e-02 | 1.101 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 7.927684e-02 | 1.101 | 0 | 0 |
| linifanib-resistant FLT3 mutants | R-HSA-9702998 | 7.927684e-02 | 1.101 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 7.927684e-02 | 1.101 | 0 | 0 |
| midostaurin-resistant FLT3 mutants | R-HSA-9702600 | 7.927684e-02 | 1.101 | 0 | 0 |
| ponatinib-resistant FLT3 mutants | R-HSA-9702614 | 7.927684e-02 | 1.101 | 0 | 0 |
| sunitinib-resistant FLT3 mutants | R-HSA-9702632 | 7.927684e-02 | 1.101 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 8.055054e-02 | 1.094 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 8.178070e-02 | 1.087 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 8.505872e-02 | 1.070 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 8.505872e-02 | 1.070 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 8.576225e-02 | 1.067 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 8.600229e-02 | 1.065 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 8.600229e-02 | 1.065 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 8.669663e-02 | 1.062 | 1 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 8.669663e-02 | 1.062 | 1 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 8.795515e-02 | 1.056 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 8.802395e-02 | 1.055 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 8.883208e-02 | 1.051 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 8.883208e-02 | 1.051 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 8.883208e-02 | 1.051 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 8.883208e-02 | 1.051 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 8.883208e-02 | 1.051 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 8.883208e-02 | 1.051 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 8.883208e-02 | 1.051 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.942998e-02 | 1.049 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 8.942998e-02 | 1.049 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 8.968298e-02 | 1.047 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 8.978479e-02 | 1.047 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 9.053174e-02 | 1.043 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.053174e-02 | 1.043 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 9.091781e-02 | 1.041 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 9.427367e-02 | 1.026 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 9.427367e-02 | 1.026 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 9.508745e-02 | 1.022 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 9.508745e-02 | 1.022 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 9.508745e-02 | 1.022 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.689355e-02 | 1.014 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 9.746863e-02 | 1.011 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 9.828339e-02 | 1.008 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 9.828478e-02 | 1.008 | 1 | 1 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 9.828478e-02 | 1.008 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 9.843037e-02 | 1.007 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 9.843037e-02 | 1.007 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 9.843037e-02 | 1.007 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.843037e-02 | 1.007 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.005190e-01 | 0.998 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.011097e-01 | 0.995 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 1.038124e-01 | 0.984 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.055162e-01 | 0.977 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 1.056886e-01 | 0.976 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 1.066947e-01 | 0.972 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 1.066947e-01 | 0.972 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.075829e-01 | 0.968 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.075829e-01 | 0.968 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.077032e-01 | 0.968 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 1.103890e-01 | 0.957 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.522732e-01 | 0.817 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.522732e-01 | 0.817 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.522732e-01 | 0.817 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 1.522732e-01 | 0.817 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.522732e-01 | 0.817 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 1.522732e-01 | 0.817 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 1.522732e-01 | 0.817 | 0 | 0 |
| RPIA deficiency: failed conversion of RU5P to R5P | R-HSA-6791461 | 1.522732e-01 | 0.817 | 0 | 0 |
| RPIA deficiency: failed conversion of R5P to RU5P | R-HSA-5659996 | 1.522732e-01 | 0.817 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.522732e-01 | 0.817 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 1.522732e-01 | 0.817 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.522732e-01 | 0.817 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.194863e-01 | 0.659 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.194863e-01 | 0.659 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 2.194863e-01 | 0.659 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.194863e-01 | 0.659 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 1.147315e-01 | 0.940 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 1.147315e-01 | 0.940 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.147315e-01 | 0.940 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.147315e-01 | 0.940 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 1.147315e-01 | 0.940 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.422527e-01 | 0.847 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 1.422527e-01 | 0.847 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 1.709762e-01 | 0.767 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.005389e-01 | 0.698 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 2.005389e-01 | 0.698 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 1.477868e-01 | 0.830 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.477868e-01 | 0.830 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.113323e-01 | 0.953 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.674144e-01 | 0.776 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.674144e-01 | 0.776 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 1.395502e-01 | 0.855 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 2.086669e-01 | 0.681 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 2.086669e-01 | 0.681 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 1.702778e-01 | 0.769 | 1 | 1 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 1.407250e-01 | 0.852 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.407250e-01 | 0.852 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.407250e-01 | 0.852 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 1.173182e-01 | 0.931 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 1.864538e-01 | 0.729 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 1.665330e-01 | 0.778 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 1.720461e-01 | 0.764 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 1.635367e-01 | 0.786 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 1.964446e-01 | 0.707 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 1.964446e-01 | 0.707 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 1.964446e-01 | 0.707 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.850007e-01 | 0.733 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 2.220394e-01 | 0.654 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 2.220394e-01 | 0.654 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 2.220394e-01 | 0.654 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.308717e-01 | 0.883 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 1.821939e-01 | 0.739 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 1.607672e-01 | 0.794 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 2.220394e-01 | 0.654 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 1.665330e-01 | 0.778 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 1.702778e-01 | 0.769 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 1.380451e-01 | 0.860 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.532470e-01 | 0.815 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 2.086669e-01 | 0.681 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 1.147315e-01 | 0.940 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 1.422527e-01 | 0.847 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 1.289771e-01 | 0.889 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 2.030999e-01 | 0.692 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 2.030999e-01 | 0.692 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 1.120360e-01 | 0.951 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 1.964446e-01 | 0.707 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 1.407250e-01 | 0.852 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 1.477868e-01 | 0.830 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 1.477868e-01 | 0.830 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 2.086669e-01 | 0.681 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 2.201617e-01 | 0.657 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 1.200618e-01 | 0.921 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 1.940386e-01 | 0.712 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 1.200851e-01 | 0.921 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 1.285301e-01 | 0.891 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 1.251028e-01 | 0.903 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.251028e-01 | 0.903 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.285301e-01 | 0.891 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 1.943191e-01 | 0.711 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 1.171966e-01 | 0.931 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 1.147315e-01 | 0.940 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 1.422527e-01 | 0.847 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 1.877452e-01 | 0.726 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 1.877452e-01 | 0.726 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 1.153187e-01 | 0.938 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 1.741257e-01 | 0.759 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 2.201617e-01 | 0.657 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 1.422527e-01 | 0.847 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 1.173182e-01 | 0.931 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 1.665330e-01 | 0.778 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 1.546256e-01 | 0.811 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.385896e-01 | 0.858 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 1.181767e-01 | 0.927 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 1.902763e-01 | 0.721 | 1 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 1.522732e-01 | 0.817 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.522732e-01 | 0.817 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 1.113323e-01 | 0.953 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 1.840853e-01 | 0.735 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 1.840853e-01 | 0.735 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.289716e-01 | 0.890 | 1 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.181714e-01 | 0.927 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 1.665330e-01 | 0.778 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 1.468429e-01 | 0.833 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 2.220394e-01 | 0.654 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 1.434186e-01 | 0.843 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 1.940386e-01 | 0.712 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 1.111011e-01 | 0.954 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.850007e-01 | 0.733 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 2.005389e-01 | 0.698 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 1.877452e-01 | 0.726 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 1.153187e-01 | 0.938 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 1.153187e-01 | 0.938 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 1.200618e-01 | 0.921 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 1.171966e-01 | 0.931 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.291320e-01 | 0.889 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 1.534019e-01 | 0.814 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 1.665330e-01 | 0.778 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 1.424470e-01 | 0.846 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 1.147315e-01 | 0.940 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.422527e-01 | 0.847 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 1.674144e-01 | 0.776 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 1.702778e-01 | 0.769 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 1.644992e-01 | 0.784 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.385896e-01 | 0.858 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.385896e-01 | 0.858 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 1.206358e-01 | 0.919 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.877452e-01 | 0.726 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 1.808404e-01 | 0.743 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 1.395502e-01 | 0.855 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 1.432693e-01 | 0.844 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 1.134482e-01 | 0.945 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 2.165003e-01 | 0.665 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 1.242327e-01 | 0.906 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 2.129359e-01 | 0.672 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 1.407250e-01 | 0.852 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 2.201617e-01 | 0.657 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.242949e-01 | 0.906 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 1.532470e-01 | 0.815 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 1.603472e-01 | 0.795 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 1.964446e-01 | 0.707 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.005389e-01 | 0.698 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.251028e-01 | 0.903 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 1.432693e-01 | 0.844 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 1.532470e-01 | 0.815 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 1.532470e-01 | 0.815 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 1.285301e-01 | 0.891 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 1.374908e-01 | 0.862 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 1.685541e-01 | 0.773 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 1.815926e-01 | 0.741 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.113323e-01 | 0.953 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 1.546256e-01 | 0.811 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 1.729360e-01 | 0.762 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 1.147315e-01 | 0.940 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 2.229928e-01 | 0.652 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 2.229928e-01 | 0.652 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 2.229928e-01 | 0.652 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 2.300711e-01 | 0.638 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 2.300711e-01 | 0.638 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 2.300711e-01 | 0.638 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 2.300711e-01 | 0.638 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 2.306275e-01 | 0.637 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 2.306275e-01 | 0.637 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 2.306275e-01 | 0.637 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 2.306275e-01 | 0.637 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 2.306275e-01 | 0.637 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 2.311991e-01 | 0.636 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 2.324960e-01 | 0.634 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 2.371969e-01 | 0.625 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 2.375851e-01 | 0.624 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.375851e-01 | 0.624 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 2.386224e-01 | 0.622 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 2.413906e-01 | 0.617 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 2.431528e-01 | 0.614 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 2.486566e-01 | 0.604 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 2.487743e-01 | 0.604 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.518537e-01 | 0.599 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 2.518537e-01 | 0.599 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 2.518537e-01 | 0.599 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 2.518537e-01 | 0.599 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 2.518537e-01 | 0.599 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 2.518537e-01 | 0.599 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 2.531352e-01 | 0.597 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 2.531352e-01 | 0.597 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 2.531352e-01 | 0.597 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 2.531352e-01 | 0.597 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 2.531352e-01 | 0.597 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 2.531352e-01 | 0.597 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 2.540965e-01 | 0.595 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 2.553164e-01 | 0.593 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 2.553164e-01 | 0.593 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 2.561298e-01 | 0.592 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 2.597598e-01 | 0.585 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 2.609730e-01 | 0.583 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 2.609730e-01 | 0.583 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 2.609730e-01 | 0.583 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 2.609730e-01 | 0.583 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 2.609730e-01 | 0.583 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 2.609730e-01 | 0.583 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 2.609730e-01 | 0.583 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 2.609730e-01 | 0.583 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 2.609730e-01 | 0.583 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 2.609730e-01 | 0.583 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 2.609730e-01 | 0.583 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 2.622924e-01 | 0.581 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 2.622924e-01 | 0.581 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 2.622924e-01 | 0.581 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 2.624813e-01 | 0.581 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 2.685693e-01 | 0.571 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 2.739160e-01 | 0.562 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 2.739160e-01 | 0.562 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.739160e-01 | 0.562 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 2.739160e-01 | 0.562 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 2.739160e-01 | 0.562 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 2.761159e-01 | 0.559 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 2.813740e-01 | 0.551 | 0 | 0 |
| Defective AHCY causes HMAHCHD | R-HSA-5578997 | 2.813740e-01 | 0.551 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 2.813740e-01 | 0.551 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 2.813740e-01 | 0.551 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 2.813740e-01 | 0.551 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 2.813740e-01 | 0.551 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 2.813740e-01 | 0.551 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 2.813740e-01 | 0.551 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 2.813740e-01 | 0.551 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 2.841180e-01 | 0.547 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 2.841496e-01 | 0.546 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 2.842014e-01 | 0.546 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 2.842014e-01 | 0.546 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 2.842014e-01 | 0.546 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 2.901041e-01 | 0.537 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 2.913458e-01 | 0.536 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 2.913458e-01 | 0.536 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 2.913458e-01 | 0.536 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 2.913458e-01 | 0.536 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 2.913458e-01 | 0.536 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 2.913458e-01 | 0.536 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 2.913458e-01 | 0.536 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 2.913458e-01 | 0.536 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 2.913458e-01 | 0.536 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 2.913458e-01 | 0.536 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 2.913458e-01 | 0.536 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 2.914926e-01 | 0.535 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 2.927096e-01 | 0.534 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 2.932497e-01 | 0.533 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 2.961647e-01 | 0.528 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 2.961647e-01 | 0.528 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 2.961647e-01 | 0.528 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 2.985103e-01 | 0.525 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 2.999990e-01 | 0.523 | 1 | 1 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 3.001715e-01 | 0.523 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 3.016775e-01 | 0.520 | 1 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 3.037925e-01 | 0.517 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 3.052104e-01 | 0.515 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 3.057021e-01 | 0.515 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 3.184840e-01 | 0.497 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 3.185128e-01 | 0.497 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.185128e-01 | 0.497 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 3.185128e-01 | 0.497 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 3.186231e-01 | 0.497 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 3.191213e-01 | 0.496 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 3.206593e-01 | 0.494 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 3.215510e-01 | 0.493 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 3.215510e-01 | 0.493 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 3.215510e-01 | 0.493 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 3.215510e-01 | 0.493 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 3.282849e-01 | 0.484 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 3.282849e-01 | 0.484 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 3.319628e-01 | 0.479 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 3.319628e-01 | 0.479 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 3.319628e-01 | 0.479 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 3.319628e-01 | 0.479 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 3.328306e-01 | 0.478 | 0 | 0 |
| PLC-gamma1 signalling | R-HSA-167021 | 3.383580e-01 | 0.471 | 0 | 0 |
| Activated NTRK3 signals through PLCG1 | R-HSA-9034793 | 3.383580e-01 | 0.471 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 3.383580e-01 | 0.471 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.383580e-01 | 0.471 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.383580e-01 | 0.471 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 3.383580e-01 | 0.471 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 3.383580e-01 | 0.471 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 3.383580e-01 | 0.471 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 3.408794e-01 | 0.467 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 3.408794e-01 | 0.467 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 3.408794e-01 | 0.467 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 3.419096e-01 | 0.466 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 3.453609e-01 | 0.462 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.467929e-01 | 0.460 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 3.467929e-01 | 0.460 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 3.472521e-01 | 0.459 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 3.480672e-01 | 0.458 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 3.514244e-01 | 0.454 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 3.514244e-01 | 0.454 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 3.514244e-01 | 0.454 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 3.542300e-01 | 0.451 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 3.585770e-01 | 0.445 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 3.609444e-01 | 0.443 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 3.631899e-01 | 0.440 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 3.642132e-01 | 0.439 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 3.642132e-01 | 0.439 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 3.695737e-01 | 0.432 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 3.762341e-01 | 0.425 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 3.762580e-01 | 0.425 | 1 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 3.808287e-01 | 0.419 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 3.808287e-01 | 0.419 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 3.808287e-01 | 0.419 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 3.808287e-01 | 0.419 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 3.808287e-01 | 0.419 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 3.808287e-01 | 0.419 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 3.808287e-01 | 0.419 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 3.838123e-01 | 0.416 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 3.842775e-01 | 0.415 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 3.851201e-01 | 0.414 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 3.853758e-01 | 0.414 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 3.853758e-01 | 0.414 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 3.853758e-01 | 0.414 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 3.908265e-01 | 0.408 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 3.908265e-01 | 0.408 | 0 | 0 |
| Activated NTRK2 signals through PLCG1 | R-HSA-9026527 | 3.908265e-01 | 0.408 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 3.908265e-01 | 0.408 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 3.908265e-01 | 0.408 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 3.908265e-01 | 0.408 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 3.908265e-01 | 0.408 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 3.908265e-01 | 0.408 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 3.965171e-01 | 0.402 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 3.991342e-01 | 0.399 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 4.022425e-01 | 0.396 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 4.022425e-01 | 0.396 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 4.073750e-01 | 0.390 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 4.073750e-01 | 0.390 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 4.073750e-01 | 0.390 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 4.096507e-01 | 0.388 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 4.096507e-01 | 0.388 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 4.096507e-01 | 0.388 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 4.096507e-01 | 0.388 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 4.096507e-01 | 0.388 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 4.096507e-01 | 0.388 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 4.096507e-01 | 0.388 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 4.096507e-01 | 0.388 | 0 | 0 |
| Disease | R-HSA-1643685 | 4.180329e-01 | 0.379 | 1 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 4.205695e-01 | 0.376 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 4.205695e-01 | 0.376 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 4.249783e-01 | 0.372 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 4.280982e-01 | 0.368 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 4.286588e-01 | 0.368 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 4.291313e-01 | 0.367 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 4.321825e-01 | 0.364 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 4.341843e-01 | 0.362 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 4.377979e-01 | 0.359 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 4.377979e-01 | 0.359 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 4.377979e-01 | 0.359 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 4.377979e-01 | 0.359 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 4.387589e-01 | 0.358 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 4.387589e-01 | 0.358 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.391371e-01 | 0.357 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.391371e-01 | 0.357 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 4.391371e-01 | 0.357 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 4.391371e-01 | 0.357 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 4.391371e-01 | 0.357 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 4.391371e-01 | 0.357 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 4.391371e-01 | 0.357 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 4.391371e-01 | 0.357 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 4.391371e-01 | 0.357 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.391371e-01 | 0.357 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 4.391371e-01 | 0.357 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 4.391371e-01 | 0.357 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 4.391371e-01 | 0.357 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 4.427148e-01 | 0.354 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 4.505943e-01 | 0.346 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 4.576034e-01 | 0.340 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 4.604422e-01 | 0.337 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 4.651961e-01 | 0.332 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 4.651961e-01 | 0.332 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 4.651961e-01 | 0.332 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 4.651961e-01 | 0.332 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.651961e-01 | 0.332 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 4.657630e-01 | 0.332 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 4.717191e-01 | 0.326 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 4.717191e-01 | 0.326 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 4.717191e-01 | 0.326 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 4.717191e-01 | 0.326 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 4.717191e-01 | 0.326 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 4.717191e-01 | 0.326 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 4.717191e-01 | 0.326 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 4.745988e-01 | 0.324 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 4.745988e-01 | 0.324 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 4.745988e-01 | 0.324 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 4.745988e-01 | 0.324 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 4.745988e-01 | 0.324 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 4.761440e-01 | 0.322 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 4.770474e-01 | 0.321 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 4.770474e-01 | 0.321 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 4.836191e-01 | 0.315 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 4.836191e-01 | 0.315 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 4.836191e-01 | 0.315 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 4.836191e-01 | 0.315 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 4.836191e-01 | 0.315 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 4.836191e-01 | 0.315 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 4.836191e-01 | 0.315 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 4.836191e-01 | 0.315 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 4.836191e-01 | 0.315 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 4.836191e-01 | 0.315 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 4.836191e-01 | 0.315 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 4.836191e-01 | 0.315 | 0 | 0 |
| Intestinal hexose absorption | R-HSA-8981373 | 4.836191e-01 | 0.315 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 4.836191e-01 | 0.315 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 4.836191e-01 | 0.315 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 4.836191e-01 | 0.315 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 4.836191e-01 | 0.315 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 4.911314e-01 | 0.309 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 4.911314e-01 | 0.309 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 4.911314e-01 | 0.309 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 4.911314e-01 | 0.309 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 4.911314e-01 | 0.309 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 4.917871e-01 | 0.308 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 4.917871e-01 | 0.308 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 4.917871e-01 | 0.308 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 4.917871e-01 | 0.308 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 4.917871e-01 | 0.308 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 4.917871e-01 | 0.308 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 4.924664e-01 | 0.308 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 4.924664e-01 | 0.308 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 5.029172e-01 | 0.299 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 5.034339e-01 | 0.298 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 5.095352e-01 | 0.293 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 5.128016e-01 | 0.290 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 5.128016e-01 | 0.290 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 5.128016e-01 | 0.290 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 5.128016e-01 | 0.290 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 5.175267e-01 | 0.286 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 5.175267e-01 | 0.286 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 5.189058e-01 | 0.285 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 5.189058e-01 | 0.285 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 5.189058e-01 | 0.285 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 5.222545e-01 | 0.282 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 5.245757e-01 | 0.280 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 5.245757e-01 | 0.280 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.245757e-01 | 0.280 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 5.245757e-01 | 0.280 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.245757e-01 | 0.280 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.245757e-01 | 0.280 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 5.245757e-01 | 0.280 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 5.245757e-01 | 0.280 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 5.245757e-01 | 0.280 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 5.245757e-01 | 0.280 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 5.245757e-01 | 0.280 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 5.245757e-01 | 0.280 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.245757e-01 | 0.280 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 5.245757e-01 | 0.280 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 5.245757e-01 | 0.280 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.245757e-01 | 0.280 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 5.245757e-01 | 0.280 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 5.245757e-01 | 0.280 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.245757e-01 | 0.280 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 5.245757e-01 | 0.280 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 5.313421e-01 | 0.275 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 5.326953e-01 | 0.274 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 5.335384e-01 | 0.273 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 5.361646e-01 | 0.271 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 5.374705e-01 | 0.270 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 5.404611e-01 | 0.267 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 5.417625e-01 | 0.266 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 5.423826e-01 | 0.266 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 5.423826e-01 | 0.266 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 5.423826e-01 | 0.266 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 5.433796e-01 | 0.265 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 5.433796e-01 | 0.265 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 5.451479e-01 | 0.263 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 5.451479e-01 | 0.263 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 5.451479e-01 | 0.263 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 5.460683e-01 | 0.263 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 5.473111e-01 | 0.262 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 5.508075e-01 | 0.259 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 5.519972e-01 | 0.258 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 5.521221e-01 | 0.258 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 5.521221e-01 | 0.258 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 5.622860e-01 | 0.250 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 5.622860e-01 | 0.250 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 5.622860e-01 | 0.250 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 5.622860e-01 | 0.250 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 5.622860e-01 | 0.250 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 5.622860e-01 | 0.250 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 5.622860e-01 | 0.250 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 5.622860e-01 | 0.250 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 5.622860e-01 | 0.250 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 5.622860e-01 | 0.250 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 5.622860e-01 | 0.250 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 5.622860e-01 | 0.250 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 5.622860e-01 | 0.250 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 5.659577e-01 | 0.247 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 5.663331e-01 | 0.247 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 5.663331e-01 | 0.247 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 5.663331e-01 | 0.247 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 5.663331e-01 | 0.247 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 5.663331e-01 | 0.247 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 5.665254e-01 | 0.247 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 5.710610e-01 | 0.243 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 5.710610e-01 | 0.243 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 5.710610e-01 | 0.243 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 5.710610e-01 | 0.243 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 5.710610e-01 | 0.243 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 5.774156e-01 | 0.239 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 5.893655e-01 | 0.230 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 5.893655e-01 | 0.230 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 5.893655e-01 | 0.230 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 5.893655e-01 | 0.230 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 5.893655e-01 | 0.230 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 5.893655e-01 | 0.230 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 5.893655e-01 | 0.230 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 5.893655e-01 | 0.230 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 5.894950e-01 | 0.230 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 5.899376e-01 | 0.229 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 5.917750e-01 | 0.228 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 5.970073e-01 | 0.224 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 5.970073e-01 | 0.224 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 5.970073e-01 | 0.224 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 5.970073e-01 | 0.224 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 5.970073e-01 | 0.224 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 5.970073e-01 | 0.224 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 5.970073e-01 | 0.224 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 5.970073e-01 | 0.224 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 5.970073e-01 | 0.224 | 0 | 0 |
| Intestinal absorption | R-HSA-8963676 | 5.970073e-01 | 0.224 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 5.970073e-01 | 0.224 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 5.970073e-01 | 0.224 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 6.003671e-01 | 0.222 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 6.016753e-01 | 0.221 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 6.051633e-01 | 0.218 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 6.072173e-01 | 0.217 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 6.072173e-01 | 0.217 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 6.072173e-01 | 0.217 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 6.074104e-01 | 0.217 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 6.074104e-01 | 0.217 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 6.085974e-01 | 0.216 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 6.114748e-01 | 0.214 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 6.114748e-01 | 0.214 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 6.114748e-01 | 0.214 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 6.114748e-01 | 0.214 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 6.114748e-01 | 0.214 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 6.114748e-01 | 0.214 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 6.114748e-01 | 0.214 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 6.114748e-01 | 0.214 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 6.114748e-01 | 0.214 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 6.187616e-01 | 0.208 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 6.187616e-01 | 0.208 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 6.218294e-01 | 0.206 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 6.220851e-01 | 0.206 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 6.222969e-01 | 0.206 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 6.246137e-01 | 0.204 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 6.247971e-01 | 0.204 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 6.247971e-01 | 0.204 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 6.265755e-01 | 0.203 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 6.289762e-01 | 0.201 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 6.289762e-01 | 0.201 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 6.289762e-01 | 0.201 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 6.289762e-01 | 0.201 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 6.289762e-01 | 0.201 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 6.289762e-01 | 0.201 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 6.289762e-01 | 0.201 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 6.289762e-01 | 0.201 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 6.326623e-01 | 0.199 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 6.326623e-01 | 0.199 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 6.326623e-01 | 0.199 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 6.326623e-01 | 0.199 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 6.326623e-01 | 0.199 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 6.326623e-01 | 0.199 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 6.335058e-01 | 0.198 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 6.370054e-01 | 0.196 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 6.416476e-01 | 0.193 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 6.529352e-01 | 0.185 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 6.529352e-01 | 0.185 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 6.529352e-01 | 0.185 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 6.529352e-01 | 0.185 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 6.529352e-01 | 0.185 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 6.579123e-01 | 0.182 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 6.579577e-01 | 0.182 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 6.579577e-01 | 0.182 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 6.579577e-01 | 0.182 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 6.584109e-01 | 0.182 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 6.584109e-01 | 0.182 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 6.584109e-01 | 0.182 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 6.584109e-01 | 0.182 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 6.584109e-01 | 0.182 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 6.584109e-01 | 0.182 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 6.584109e-01 | 0.182 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 6.584109e-01 | 0.182 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 6.587457e-01 | 0.181 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 6.587457e-01 | 0.181 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 6.608368e-01 | 0.180 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.681958e-01 | 0.175 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 6.684045e-01 | 0.175 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 6.723053e-01 | 0.172 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 6.723053e-01 | 0.172 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 6.723053e-01 | 0.172 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 6.723053e-01 | 0.172 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 6.723053e-01 | 0.172 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 6.731660e-01 | 0.172 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 6.731660e-01 | 0.172 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 6.737253e-01 | 0.172 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 6.737253e-01 | 0.172 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 6.737253e-01 | 0.172 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 6.737253e-01 | 0.172 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 6.737253e-01 | 0.172 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 6.851827e-01 | 0.164 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 6.851827e-01 | 0.164 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 6.855120e-01 | 0.164 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 6.855120e-01 | 0.164 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 6.855120e-01 | 0.164 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 6.855120e-01 | 0.164 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 6.855120e-01 | 0.164 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 6.855120e-01 | 0.164 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 6.855120e-01 | 0.164 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 6.859318e-01 | 0.164 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 6.889505e-01 | 0.162 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 6.889505e-01 | 0.162 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 6.889505e-01 | 0.162 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 6.889505e-01 | 0.162 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 6.907882e-01 | 0.161 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 6.907882e-01 | 0.161 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 6.973930e-01 | 0.157 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 7.083425e-01 | 0.150 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 7.084027e-01 | 0.150 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 7.084027e-01 | 0.150 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.084027e-01 | 0.150 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 7.084027e-01 | 0.150 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 7.084027e-01 | 0.150 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 7.104644e-01 | 0.148 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 7.104644e-01 | 0.148 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.104644e-01 | 0.148 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 7.104644e-01 | 0.148 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 7.104644e-01 | 0.148 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 7.104644e-01 | 0.148 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.104644e-01 | 0.148 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 7.160422e-01 | 0.145 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 7.172000e-01 | 0.144 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 7.177854e-01 | 0.144 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 7.177854e-01 | 0.144 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 7.194588e-01 | 0.143 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 7.206579e-01 | 0.142 | 1 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 7.251702e-01 | 0.140 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 7.251702e-01 | 0.140 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 7.251702e-01 | 0.140 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.251702e-01 | 0.140 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 7.251702e-01 | 0.140 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 7.263162e-01 | 0.139 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 7.314047e-01 | 0.136 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 7.314047e-01 | 0.136 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 7.334384e-01 | 0.135 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 7.334384e-01 | 0.135 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 7.334384e-01 | 0.135 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 7.334384e-01 | 0.135 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 7.334384e-01 | 0.135 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 7.334384e-01 | 0.135 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 7.334384e-01 | 0.135 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 7.334384e-01 | 0.135 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 7.334384e-01 | 0.135 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.334384e-01 | 0.135 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 7.334384e-01 | 0.135 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.334384e-01 | 0.135 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 7.334384e-01 | 0.135 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 7.334384e-01 | 0.135 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 7.334384e-01 | 0.135 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.334384e-01 | 0.135 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 7.334384e-01 | 0.135 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 7.334384e-01 | 0.135 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 7.365271e-01 | 0.133 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 7.406967e-01 | 0.130 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 7.411142e-01 | 0.130 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 7.411142e-01 | 0.130 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 7.411142e-01 | 0.130 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 7.445011e-01 | 0.128 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 7.463599e-01 | 0.127 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 7.509780e-01 | 0.124 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 7.515032e-01 | 0.124 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 7.538412e-01 | 0.123 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 7.541273e-01 | 0.123 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 7.545907e-01 | 0.122 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 7.545907e-01 | 0.122 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 7.562598e-01 | 0.121 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 7.562598e-01 | 0.121 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 7.562598e-01 | 0.121 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 7.562598e-01 | 0.121 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 7.562598e-01 | 0.121 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 7.563998e-01 | 0.121 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 7.691593e-01 | 0.114 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 7.691593e-01 | 0.114 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 7.704794e-01 | 0.113 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 7.706332e-01 | 0.113 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 7.706332e-01 | 0.113 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 7.706332e-01 | 0.113 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 7.706332e-01 | 0.113 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 7.706332e-01 | 0.113 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 7.706332e-01 | 0.113 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 7.709412e-01 | 0.113 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 7.740657e-01 | 0.111 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 7.740657e-01 | 0.111 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 7.740657e-01 | 0.111 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 7.740657e-01 | 0.111 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 7.740657e-01 | 0.111 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 7.740657e-01 | 0.111 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 7.740657e-01 | 0.111 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 7.740657e-01 | 0.111 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 7.740657e-01 | 0.111 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 7.740657e-01 | 0.111 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 7.740657e-01 | 0.111 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 7.785823e-01 | 0.109 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 7.807410e-01 | 0.107 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 7.807410e-01 | 0.107 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 7.807410e-01 | 0.107 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 7.821992e-01 | 0.107 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 7.842616e-01 | 0.106 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 7.919963e-01 | 0.101 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 7.919963e-01 | 0.101 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 7.919963e-01 | 0.101 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 7.919963e-01 | 0.101 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 7.919963e-01 | 0.101 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 7.919963e-01 | 0.101 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 7.919963e-01 | 0.101 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 7.919963e-01 | 0.101 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 7.919963e-01 | 0.101 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 7.919963e-01 | 0.101 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 7.919963e-01 | 0.101 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 7.919963e-01 | 0.101 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 7.932871e-01 | 0.101 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 7.959616e-01 | 0.099 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 7.971727e-01 | 0.098 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 7.971727e-01 | 0.098 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 7.971727e-01 | 0.098 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 7.975149e-01 | 0.098 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 8.018113e-01 | 0.096 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 8.024653e-01 | 0.096 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 8.025970e-01 | 0.096 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 8.085048e-01 | 0.092 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 8.085048e-01 | 0.092 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.085048e-01 | 0.092 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 8.085048e-01 | 0.092 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 8.085048e-01 | 0.092 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 8.085048e-01 | 0.092 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 8.085048e-01 | 0.092 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 8.085048e-01 | 0.092 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 8.085048e-01 | 0.092 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 8.085048e-01 | 0.092 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 8.085048e-01 | 0.092 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 8.085048e-01 | 0.092 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.085048e-01 | 0.092 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 8.093945e-01 | 0.092 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 8.117343e-01 | 0.091 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 8.141037e-01 | 0.089 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 8.204406e-01 | 0.086 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 8.209550e-01 | 0.086 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 8.209550e-01 | 0.086 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 8.223518e-01 | 0.085 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 8.237041e-01 | 0.084 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 8.237041e-01 | 0.084 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 8.237041e-01 | 0.084 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 8.237041e-01 | 0.084 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 8.237041e-01 | 0.084 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 8.237041e-01 | 0.084 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 8.237041e-01 | 0.084 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 8.237041e-01 | 0.084 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 8.237041e-01 | 0.084 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 8.237041e-01 | 0.084 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 8.237041e-01 | 0.084 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 8.237041e-01 | 0.084 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 8.237041e-01 | 0.084 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.237041e-01 | 0.084 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 8.288122e-01 | 0.082 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 8.318821e-01 | 0.080 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 8.318821e-01 | 0.080 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 8.318821e-01 | 0.080 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 8.318821e-01 | 0.080 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 8.368567e-01 | 0.077 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 8.369254e-01 | 0.077 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 8.376978e-01 | 0.077 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 8.376978e-01 | 0.077 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 8.376978e-01 | 0.077 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 8.376978e-01 | 0.077 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 8.376978e-01 | 0.077 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 8.376978e-01 | 0.077 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 8.376978e-01 | 0.077 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 8.389852e-01 | 0.076 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 8.422036e-01 | 0.075 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 8.422036e-01 | 0.075 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 8.505815e-01 | 0.070 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 8.505815e-01 | 0.070 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 8.505815e-01 | 0.070 | 0 | 0 |
| PKA activation | R-HSA-163615 | 8.505815e-01 | 0.070 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 8.505815e-01 | 0.070 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 8.505815e-01 | 0.070 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.505815e-01 | 0.070 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.517800e-01 | 0.070 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 8.519467e-01 | 0.070 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 8.519467e-01 | 0.070 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 8.519467e-01 | 0.070 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 8.519467e-01 | 0.070 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 8.539710e-01 | 0.069 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 8.539845e-01 | 0.069 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 8.591487e-01 | 0.066 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 8.611382e-01 | 0.065 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 8.624431e-01 | 0.064 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 8.624431e-01 | 0.064 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 8.624431e-01 | 0.064 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 8.624431e-01 | 0.064 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.624431e-01 | 0.064 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 8.624431e-01 | 0.064 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 8.659287e-01 | 0.063 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 8.698042e-01 | 0.061 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 8.720348e-01 | 0.059 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 8.720348e-01 | 0.059 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 8.733638e-01 | 0.059 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 8.733638e-01 | 0.059 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 8.733638e-01 | 0.059 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.733638e-01 | 0.059 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 8.733638e-01 | 0.059 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 8.733638e-01 | 0.059 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 8.770837e-01 | 0.057 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 8.779702e-01 | 0.057 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 8.779702e-01 | 0.057 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 8.834181e-01 | 0.054 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 8.834181e-01 | 0.054 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 8.834181e-01 | 0.054 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 8.834181e-01 | 0.054 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 8.834181e-01 | 0.054 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 8.834181e-01 | 0.054 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 8.856300e-01 | 0.053 | 0 | 0 |
| Depurination | R-HSA-73927 | 8.856609e-01 | 0.053 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 8.856609e-01 | 0.053 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 8.919318e-01 | 0.050 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 8.926747e-01 | 0.049 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 8.997116e-01 | 0.046 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 9.011968e-01 | 0.045 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.011968e-01 | 0.045 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.011968e-01 | 0.045 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 9.011968e-01 | 0.045 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.061170e-01 | 0.043 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.069246e-01 | 0.042 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.090427e-01 | 0.041 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.090427e-01 | 0.041 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.090427e-01 | 0.041 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.090427e-01 | 0.041 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.090427e-01 | 0.041 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.090427e-01 | 0.041 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.090427e-01 | 0.041 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.121381e-01 | 0.040 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.141325e-01 | 0.039 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.141325e-01 | 0.039 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 9.145422e-01 | 0.039 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.162660e-01 | 0.038 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.162660e-01 | 0.038 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 9.162660e-01 | 0.038 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 9.162660e-01 | 0.038 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 9.162660e-01 | 0.038 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.162660e-01 | 0.038 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.177955e-01 | 0.037 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.189926e-01 | 0.037 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.198405e-01 | 0.036 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.229160e-01 | 0.035 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.229160e-01 | 0.035 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.229160e-01 | 0.035 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 9.229160e-01 | 0.035 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.252981e-01 | 0.034 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 9.264544e-01 | 0.033 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 9.279419e-01 | 0.032 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 9.279667e-01 | 0.032 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 9.279667e-01 | 0.032 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.280973e-01 | 0.032 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.280973e-01 | 0.032 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.280973e-01 | 0.032 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.290383e-01 | 0.032 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 9.290383e-01 | 0.032 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.290383e-01 | 0.032 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.290383e-01 | 0.032 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 9.290383e-01 | 0.032 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 9.327788e-01 | 0.030 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.346747e-01 | 0.029 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 9.352973e-01 | 0.029 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.357433e-01 | 0.029 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.371706e-01 | 0.028 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.371706e-01 | 0.028 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.371706e-01 | 0.028 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.398637e-01 | 0.027 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 9.398928e-01 | 0.027 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.446408e-01 | 0.025 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.446408e-01 | 0.025 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.446408e-01 | 0.025 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.446408e-01 | 0.025 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 9.446408e-01 | 0.025 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 9.451504e-01 | 0.024 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 9.451504e-01 | 0.024 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.456967e-01 | 0.024 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.465498e-01 | 0.024 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.487689e-01 | 0.023 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.490386e-01 | 0.023 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.490386e-01 | 0.023 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.530874e-01 | 0.021 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.553339e-01 | 0.020 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 9.568147e-01 | 0.019 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.568147e-01 | 0.019 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.568147e-01 | 0.019 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.580935e-01 | 0.019 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.580935e-01 | 0.019 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 9.605901e-01 | 0.017 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.605901e-01 | 0.017 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.628159e-01 | 0.016 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 9.634049e-01 | 0.016 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.634049e-01 | 0.016 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.634049e-01 | 0.016 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.663130e-01 | 0.015 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.663130e-01 | 0.015 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.689902e-01 | 0.014 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.714547e-01 | 0.013 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 9.714547e-01 | 0.013 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.720599e-01 | 0.012 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.725291e-01 | 0.012 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.728651e-01 | 0.012 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.737235e-01 | 0.012 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.737235e-01 | 0.012 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 9.737924e-01 | 0.012 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 9.737924e-01 | 0.012 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 9.737924e-01 | 0.012 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.741335e-01 | 0.011 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.741335e-01 | 0.011 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.741335e-01 | 0.011 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.743902e-01 | 0.011 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.761292e-01 | 0.010 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.772476e-01 | 0.010 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.772476e-01 | 0.010 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.777537e-01 | 0.010 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.795047e-01 | 0.009 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.802297e-01 | 0.009 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.811341e-01 | 0.008 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.811341e-01 | 0.008 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 9.826340e-01 | 0.008 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.832653e-01 | 0.007 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.840148e-01 | 0.007 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.840148e-01 | 0.007 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.847054e-01 | 0.007 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.864559e-01 | 0.006 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.864739e-01 | 0.006 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.875329e-01 | 0.005 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 9.875329e-01 | 0.005 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.882811e-01 | 0.005 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.882811e-01 | 0.005 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.884112e-01 | 0.005 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 9.889461e-01 | 0.005 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.890065e-01 | 0.005 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.894371e-01 | 0.005 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.895504e-01 | 0.005 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.902772e-01 | 0.004 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.902772e-01 | 0.004 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.917625e-01 | 0.004 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.917625e-01 | 0.004 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.918299e-01 | 0.004 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 9.920277e-01 | 0.003 | 0 | 0 |
| Cytosolic sulfonation of small molecules | R-HSA-156584 | 9.924178e-01 | 0.003 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.934292e-01 | 0.003 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.935763e-01 | 0.003 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.936747e-01 | 0.003 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.937748e-01 | 0.003 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.940874e-01 | 0.003 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.945579e-01 | 0.002 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.949909e-01 | 0.002 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.953322e-01 | 0.002 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.953895e-01 | 0.002 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.953895e-01 | 0.002 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.954692e-01 | 0.002 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.960942e-01 | 0.002 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.964051e-01 | 0.002 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.964051e-01 | 0.002 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.964909e-01 | 0.002 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.966912e-01 | 0.001 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.967753e-01 | 0.001 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.970769e-01 | 0.001 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.971971e-01 | 0.001 | 0 | 0 |
| Digestion and absorption | R-HSA-8963743 | 9.971971e-01 | 0.001 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.974202e-01 | 0.001 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.974202e-01 | 0.001 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.974707e-01 | 0.001 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.977880e-01 | 0.001 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.978147e-01 | 0.001 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.979401e-01 | 0.001 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.979887e-01 | 0.001 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.980958e-01 | 0.001 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.981489e-01 | 0.001 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.985386e-01 | 0.001 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.985386e-01 | 0.001 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.985569e-01 | 0.001 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.985569e-01 | 0.001 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.985569e-01 | 0.001 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.987776e-01 | 0.001 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.988750e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.988853e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.992572e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.992572e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.993709e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.993709e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.995096e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.995196e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.995485e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.995761e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.995815e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.995946e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.996178e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.997845e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.998034e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.998468e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.998590e-01 | 0.000 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.998590e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.998769e-01 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.998935e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999142e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999676e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999884e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999950e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999972e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999979e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999982e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999982e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999984e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.999984e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999986e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999989e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999991e-01 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 9.999992e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999992e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999995e-01 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 9.999997e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999998e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 9.999998e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999999e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999999e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
