IKKA

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0MZ66 S444 Sugiyama SHTN1 KIAA1598 RPVNQTARPKTKPESSKGCEsAVDELKGILGtLNKSTSSRs
A0MZ66 S467 Sugiyama SHTN1 KIAA1598 DELKGILGtLNKSTSSRsLKsLDPENsEtELERILRRRKVt
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NKT7 S980 Sugiyama RGPD3 RGP3 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
O00273 S37 Sugiyama DFFA DFF1 DFF45 H13 TLKPCLLRRNysREQHGVAAsCLEDLRSKACDILAIDKSLT
O00429 S44 Sugiyama DNM1L DLP1 DRP1 QLPQIVVVGTQSSGKSsVLEsLVGRDLLPRGTGIVTRRPLI
O14545 S320 Sugiyama TRAFD1 FLN29 YPEELLIDHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQN
O14545 S409 Sugiyama TRAFD1 FLN29 CDQRPATATNHVTEGIPRLDsQPQEtsPELPRRRVRHQGDL
O14715 S979 Sugiyama RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
O14920 S177 SIGNOR|ELM IKBKB IKKB EQRLIHKIIDLGYAKELDQGsLCTsFVGTLQyLAPELLEQQ
O14920 S181 SIGNOR|ELM IKBKB IKKB IHKIIDLGYAKELDQGsLCTsFVGTLQyLAPELLEQQKyTV
O14920 S670 ELM IKBKB IKKB RQKELWNLLKIACSKVRGPVsGsPDsMNAsRLsQPGQLMsQ
O14920 S672 ELM IKBKB IKKB KELWNLLKIACSKVRGPVsGsPDsMNAsRLsQPGQLMsQPs
O14920 S675 ELM IKBKB IKKB WNLLKIACSKVRGPVsGsPDsMNAsRLsQPGQLMsQPstAs
O14920 S682 ELM IKBKB IKKB CSKVRGPVsGsPDsMNAsRLsQPGQLMsQPstAsNsLPEPA
O14920 S689 ELM IKBKB IKKB VsGsPDsMNAsRLsQPGQLMsQPstAsNsLPEPAKKsEELV
O14920 S692 ELM IKBKB IKKB sPDsMNAsRLsQPGQLMsQPstAsNsLPEPAKKsEELVAEA
O14920 S695 ELM IKBKB IKKB sMNAsRLsQPGQLMsQPstAsNsLPEPAKKsEELVAEAHNL
O14920 S697 ELM IKBKB IKKB NAsRLsQPGQLMsQPstAsNsLPEPAKKsEELVAEAHNLCT
O14920 S705 ELM IKBKB IKKB GQLMsQPstAsNsLPEPAKKsEELVAEAHNLCTLLENAIQD
O14920 S733 ELM IKBKB IKKB HNLCTLLENAIQDTVREQDQsFTALDWsWLQTEEEEHsCLE
O14920 S740 ELM IKBKB IKKB ENAIQDTVREQDQsFTALDWsWLQTEEEEHsCLEQAs____
O14920 S750 ELM IKBKB IKKB QDQsFTALDWsWLQTEEEEHsCLEQAs______________
O14965 T288 GPS6 AURKA AIK AIRK1 ARK1 AURA AYK1 BTAK IAK1 STK15 STK6 GELKIADFGWsVHAPssRRttLCGTLDYLPPEMIEGRMHDE
O14974 S903 Sugiyama PPP1R12A MBS MYPT1 QtDsIsRyETssTsAGDRyDsLLGRsGsysYLEERKPYSSR
O14974 S912 Sugiyama PPP1R12A MBS MYPT1 TssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDSTDF
O15111 S123 Sugiyama CHUK IKKA TCF16 LRKLLNKPENCCGLKESQILsLLsDIGSGIRYLHENKIIHR
O15111 S126 Sugiyama CHUK IKKA TCF16 LLNKPENCCGLKESQILsLLsDIGSGIRYLHENKIIHRDLK
O15111 S249 Sugiyama CHUK IKKA TCF16 TWHEKIKKKDPKCIFACEEMsGEVRFSSHLPQPNSLCSLVV
O15111 S351 Sugiyama CHUK IKKA TCF16 DESLHSLQSRIEREtGINTGsQELLsETGIsLDPRKPAsQC
O15111 S356 Sugiyama CHUK IKKA TCF16 SLQSRIEREtGINTGsQELLsETGIsLDPRKPAsQCVLDGV
O15111 S361 Sugiyama CHUK IKKA TCF16 IEREtGINTGsQELLsETGIsLDPRKPAsQCVLDGVRGCDs
O15111 S369 Sugiyama CHUK IKKA TCF16 TGsQELLsETGIsLDPRKPAsQCVLDGVRGCDsYMVYLFDK
O15111 S381 Sugiyama CHUK IKKA TCF16 sLDPRKPAsQCVLDGVRGCDsYMVYLFDKSKtVyEGPFAsR
O15111 S400 Sugiyama CHUK IKKA TCF16 DsYMVYLFDKSKtVyEGPFAsRsLsDCVNYIVQDsKIQLPI
O15111 S402 Sugiyama CHUK IKKA TCF16 YMVYLFDKSKtVyEGPFAsRsLsDCVNYIVQDsKIQLPIIQ
O15111 S404 Sugiyama CHUK IKKA TCF16 VYLFDKSKtVyEGPFAsRsLsDCVNYIVQDsKIQLPIIQLR
O15111 S414 Sugiyama CHUK IKKA TCF16 yEGPFAsRsLsDCVNYIVQDsKIQLPIIQLRKVWAEAVHYV
O15111 S559 Sugiyama CHUK IKKA TCF16 AEIMELQKSPYGRRQGDLMEsLEQRAIDLYKQLKHRPSDHs
O15111 S579 Sugiyama CHUK IKKA TCF16 sLEQRAIDLYKQLKHRPSDHsYSDStEMVKIIVHtVQsQDR
O15111 S596 Sugiyama CHUK IKKA TCF16 SDHsYSDStEMVKIIVHtVQsQDRVLKELFGHLSKLLGCKQ
O15111 T23 Sugiyama CHUK IKKA TCF16 RPPGLRPGAGGPWEMRERLGtGGFGNVCLYQHRELDLKIAI
O15111 T294 Sugiyama CHUK IKKA TCF16 NWLQLMLNWDPQQRGGPVDLtLKQPRCFVLMDHILNLKIVH
O15111 T345 Sugiyama CHUK IKKA TCF16 SFLLPPDESLHSLQSRIEREtGINTGsQELLsETGIsLDPR
O15111 T392 Sugiyama CHUK IKKA TCF16 VLDGVRGCDsYMVYLFDKSKtVyEGPFAsRsLsDCVNYIVQ
O15111 T584 Sugiyama CHUK IKKA TCF16 AIDLYKQLKHRPSDHsYSDStEMVKIIVHtVQsQDRVLKEL
O15111 T593 Sugiyama CHUK IKKA TCF16 HRPSDHsYSDStEMVKIIVHtVQsQDRVLKELFGHLSKLLG
O15111 Y394 Sugiyama CHUK IKKA TCF16 DGVRGCDsYMVYLFDKSKtVyEGPFAsRsLsDCVNYIVQDs
O43524 S644 SIGNOR|EPSD|PSP FOXO3 FKHRL1 FOXO3A MEsIIRSELMDADGLDFNFDsLISTQNVVGLNVGNFTGAKQ
O43715 S32 Sugiyama TRIAP1 15E1.1 HSPC132 KREYDQCFNRWFAEKFLKGDssGDPCTDLFKRYQQCVQKAI
O43823 S323 Sugiyama AKAP8 AKAP95 RKRKQFQLyEEPDtKLARVDsEGDFsENDDAAGDFRsGDEE
O43852 S261 Sugiyama CALU RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK
O43852 S277 Sugiyama CALU WILPsDyDHAEAEARHLVyEsDQNKDGKLTKEEIVDKyDLF
O43852 S44 Sugiyama CALU KKDRVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQL
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60220 S57 Sugiyama TIMM8A DDP DDP1 TIM8A HQMTELCWEKCMDKPGPKLDsRAEACFVNCVERFIDTSQFI
O60220 S94 Sugiyama TIMM8A DDP DDP1 TIM8A SQFILNRLEQTQKSKPVFSEsLsD_________________
O60716 S230 Sugiyama CTNND1 KIAA0384 PDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRA
O60749 S265 Sugiyama SNX2 TRG9 RTVKHPTLLQDPDLRQFLEssELPRAVNTQALsGAGILRMV
O60841 S182 Sugiyama EIF5B IF2 KIAA0741 DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK
O60841 S214 Sugiyama EIF5B IF2 KIAA0741 LQsRKGQKKNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAE
O60841 S66 Sugiyama EIF5B IF2 KIAA0741 KEKKKQDFDEDDILKELEELsLEAQGIKADREtVAVKPTEN
O75347 S103 Sugiyama TBCA ENEKDLEEAEEyKEARLVLDsVKLEA_______________
O75533 T316 Sugiyama SF3B1 SAP155 tPKtERDtPGHGsGWAEtPRtDRGGDsIGEtPtPGAsKRKs
O75683 S13 Sugiyama SURF6 SURF-6 ________MASLLAKDAyLQsLAKKICSHsAPEQQARTRAG
O75821 S189 Sugiyama EIF3G EIF3S4 CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK
O75925 S90 iPTMNet PIAS1 DDXBP1 MTPADLSIPNVHSSPMPATLsPSTIPQLTYDGHPASSPLLP
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95757 S599 Sugiyama HSPA4L APG1 HSPH3 OSP94 sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00558 S415 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GGGAsLELLEGKVLPGVDALsNI__________________
P01106 S82 PSP MYC BHLHE39 EDIWKKFELLPtPPLsPsRRsGLCsPSyVAVTPFsLRGDND
P01106 S86 PSP MYC BHLHE39 KKFELLPtPPLsPsRRsGLCsPSyVAVTPFsLRGDNDGGGG
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02786 S137 Sugiyama TFRC PAARRLyWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREA
P03372 S118 EPSD|PSP ESR1 ESR NR3A1 PPLNsVsPsPLMLLHPPPQLsPFLQPHGQQVPYYLENEPSG
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04083 S182 Sugiyama ANXA1 ANX1 LPC1 RDLAKDItsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsD
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 S312 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA
P04406 S321 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406 Y314 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04792 S83 Sugiyama HSPB1 HSP27 HSP28 IEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNH
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05387 S29 Sugiyama RPLP2 D11S2243E RPP2 LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK
P05388 S307 Sugiyama RPLP0 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05783 S93 Sugiyama KRT18 CYK18 PIG46 GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S291 Sugiyama KRT8 CYK8 ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P06733 S27 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL
P06733 S291 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA
P06733 S349 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 Y287 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 PsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKF
P06748 S137 Sugiyama NPM1 NPM VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK
P06748 S43 Sugiyama NPM1 NPM LKADKDyHFKVDNDENEHQLsLRTVsLGAGAKDELHIVEAE
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 S320 Sugiyama LDHB GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______
P07237 S427 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB WDKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFP
P07237 S439 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB NIVIAKMDstANEVEAVKVHsFPtLKFFPAsADRtVIDyNG
P07237 S88 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNG
P07237 T442 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB IAKMDstANEVEAVKVHsFPtLKFFPAsADRtVIDyNGERt
P07237 T85 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB KAAGKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFF
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07711 T332 Sugiyama CTSL CTSL1 VKMAKDRRNHCGIAsAAsyPtV___________________
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07900 S50 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P08195 S598 Sugiyama SLC3A2 MDU1 LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08238 S45 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S535 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
P08670 S325 Sugiyama VIM NNDALRQAKQESTEYRRQVQsLtCEVDALKGtNEsLERQMR
P08670 S430 Sugiyama VIM RIsLPLPNFssLNLREtNLDsLPLVDtHsKRTLLIKtVEtR
P08708 S89 Sugiyama RPS17 RPS17L ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P09234 S48 Sugiyama SNRPC RKHKENVKDYYQKWMEEQAQsLIDKTTAAFQQGKIPPTPFS
P09382 S63 Sugiyama LGALS1 CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P0C0S5 S99 Sugiyama H2AZ1 H2AFZ H2AZ VKRITPRHLQLAIRGDEELDsLIKATIAGGGVIPHIHKSLI
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DJD0 S964 Sugiyama RGPD1 RANBP2L6 RGP1 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDPNFKGFSGAG
P0DPH7 S48 Sugiyama TUBA3C TUBA2 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7 S54 Sugiyama TUBA3C TUBA2 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P0DPH7 T41 Sugiyama TUBA3C TUBA2 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10809 S453 Sugiyama HSPD1 HSP60 EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 S544 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KYKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKIND
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11586 T128 Sugiyama MTHFD1 MTHFC MTHFD SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12277 S164 Sugiyama CKB CKBB PHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAEQ
P13073 S72 Sugiyama COX4I1 COX4 VKHLSASQKALKEKEKASWssLsMDEKVELYRIKFKEsFAE
P13489 S290 Sugiyama RNH1 PRI RNH AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S593 Sugiyama EEF2 EF2 SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13798 S8 Sugiyama APEH D3F15S2 D3S48E DNF15S2 _____________MERQVLLsEPEEAAALyRGLSRQPALsA
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P14314 S126 Sugiyama PRKCSH G19P1 yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 T195 Sugiyama PKM OIP3 PK2 PK3 PKM2 yVDDGLISLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAA
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14625 S106 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S523 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 RtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAG
P14649 S87 Sugiyama MYL6B MLC1SA EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK
P15311 S536 Sugiyama EZR VIL2 KRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNE
P15311 T533 Sugiyama EZR VIL2 NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII
P15531 S120 Sugiyama NME1 NDPKA NM23 KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P15531 S122 Sugiyama NME1 NDPKA NM23 GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P15880 S206 Sugiyama RPS2 RPS4 GRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDCytsA
P16070 S71 Sugiyama CD44 LHR MDU2 MDU3 MIC4 DLCKAFNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRI
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P17544 S44 Sugiyama ATF7 ATFA LAVHKHKHEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEV
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18615 S113 Sugiyama NELFE RD RDBP EGKLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLy
P18615 S135 Sugiyama NELFE RD RDBP sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18754 S90 Sugiyama RCC1 CHC1 VQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsVEGSEM
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P19338 S619 Sugiyama NCL RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK
P19838 S923 SIGNOR|ELM|EPSD|PSP NFKB1 sLPLsPAstRQQIDELRDSDsVCDsGVEtsFRKLsFtEsLt
P19838 S927 GPS6|SIGNOR|ELM|EPSD|PSP NFKB1 sPAstRQQIDELRDSDsVCDsGVEtsFRKLsFtEsLtSGAS
P19838 S932 SIGNOR|EPSD|PSP NFKB1 RQQIDELRDSDsVCDsGVEtsFRKLsFtEsLtSGASLLTLN
P19838 T931 SIGNOR NFKB1 tRQQIDELRDSDsVCDsGVEtsFRKLsFtEsLtSGASLLTL
P20618 S151 Sugiyama PSMB1 PSC5 PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA
P20749 S122 SIGNOR BCL3 BCL4 D19S37 PLVNLPTPLYPMMCPMEHPLsADIAMATRADEDGDTPLHIA
P20749 S454 SIGNOR|EPSD|PSP BCL3 BCL4 D19S37 FAGVLRGPGRPVPPSPAPGGs____________________
P22692 S255 Sugiyama IGFBP4 IBP4 VKLPGGLEPKGELDCHQLADsFRE_________________
P23396 S35 Sugiyama RPS3 OK/SW-cl.26 GIFKAELNEFLtRELAEDGysGVEVRVtPTRTEIIILATRT
P23588 S122 Sugiyama EIF4B NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA
P23588 S207 Sugiyama EIF4B DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR
P24385 T286 SIGNOR|ELM|EPSD|PSP CCND1 BCL1 PRAD1 MDPKAAEEEEEEEEEVDLACtPtDVRDVDI___________
P24752 S218 Sugiyama ACAT1 ACAT MAT ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV
P25054 S1389 Sugiyama APC DP2.5 PKsPPEHYVQETPLMFsRCTsVSsLDSFESRSIASSVQSEP
P25705 S53 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM ARNFHASNTHLQKtGtAEMssILEERILGADtsVDLEETGR
P25705 S76 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM EERILGADtsVDLEETGRVLsIGDGIARVHGLRNVQAEEMV
P25963 S32 SIGNOR|ELM|EPSD|PSP NFKBIA IKBA MAD3 NFKBI AMEGPRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEI
P25963 S36 SIGNOR|ELM|EPSD|PSP NFKBIA IKBA MAD3 NFKBI PRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEIRLEP
P26038 S527 Sugiyama MSN ERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHAE
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26373 S109 Sugiyama RPL13 BBC1 OK/SW-cl.46 KVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILFPR
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T107 Sugiyama RPL13 BBC1 OK/SW-cl.46 HKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILF
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27695 S129 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 QELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDE
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P27824 S554 Sugiyama CANX EKDKGDEEEEGEEKLEEKQKsDAEEDGGtVsQEEEDRKPKA
P28066 S180 Sugiyama PSMA5 GtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSLI
P28340 S1064 Sugiyama POLD1 POLD LNALEERFSRLWTQCQRCQGsLHEDVICTSRDCPIFyMRKK
P29084 S211 Sugiyama GTF2E2 TF2E2 FVNRPDKKKILFFNDKSCQFsVDEEFQKLWRSVTVDsMDEE
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 S60 Sugiyama EEF1D EF1D ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL
P29692 S86 Sugiyama EEF1D EF1D GPGAssGtsGDHGELVVRIAsLEVENQsLRGVVQELQQAIs
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050 S157 Sugiyama RPL12 QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P30086 S139 Sugiyama PEBP1 PBP PEBP RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30086 S54 Sugiyama PEBP1 PBP PEBP VDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAP
P30086 S60 Sugiyama PEBP1 PBP PEBP VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P30533 S137 Sugiyama LRPAP1 A2MRAP VILAKYGLDGKKDARQVtsNsLsGtQEDGLDDPRLEKLWHK
P30626 S111 Sugiyama SRI GFNEFKELWAVLNGWRQHFIsFDTDRSGTVDPQELQKALtt
P31943 S269 Sugiyama HNRNPH1 HNRPH HNRPH1 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH
P31943 S272 Sugiyama HNRNPH1 HNRPH HNRPH1 GYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGHCVH
P31943 T286 Sugiyama HNRNPH1 HNRPH HNRPH1 yCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDIy
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948 S42 Sugiyama STIP1 DALQCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDGC
P31948 S45 Sugiyama STIP1 QCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDGCKtV
P32969 S182 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 QQATTVKNKDIRKFLDGIyVsEKGtVQQADE__________
P33240 S336 Sugiyama CSTF2 PtPRGLLGDAPNDPRGGtLLsVtGEVEPRGYLGPPHQGPPM
P33316 S164 Sugiyama DUT YTIPPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDV
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P35222 S33 EPSD|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 AMEPDRKAAVsHWQQQsyLDsGIHsGATtTAPsLsGKGNPE
P35222 S37 EPSD|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 DRKAAVsHWQQQsyLDsGIHsGATtTAPsLsGKGNPEEEDV
P35222 S45 EPSD|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 WQQQsyLDsGIHsGATtTAPsLsGKGNPEEEDVDTsQVLyE
P35222 T41 EPSD|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 AVsHWQQQsyLDsGIHsGATtTAPsLsGKGNPEEEDVDTsQ
P35251 S253 Sugiyama RFC1 RFC140 DEEPKTKKARKDTEAGETFSsVQANLSKAEKHKYPHKVKTA
P35568 S268 ELM IRS1 NMHETILEAMRAMSDEFRPRsKsQsssNCSNPISVPLRRHH
P35568 S270 ELM IRS1 HETILEAMRAMSDEFRPRsKsQsssNCSNPISVPLRRHHLN
P35568 S272 ELM IRS1 TILEAMRAMSDEFRPRsKsQsssNCSNPISVPLRRHHLNNP
P35568 S274 ELM IRS1 LEAMRAMSDEFRPRsKsQsssNCSNPISVPLRRHHLNNPPP
P35568 S307 ELM IRS1 HHLNNPPPSQVGLTRRsRtEsItAtsPAsMVGGKPGsFRVR
P35568 S312 ELM IRS1 PPPSQVGLTRRsRtEsItAtsPAsMVGGKPGsFRVRAssDG
P35568 S341 ELM IRS1 PGsFRVRAssDGEGtMsRPAsVDGsPVsPstNRTHAHRHRG
P35568 S345 ELM IRS1 RVRAssDGEGtMsRPAsVDGsPVsPstNRTHAHRHRGsARL
P35568 S527 ELM IRS1 AGDEAASAADLDNRFRKRtHsAGtsPTITHQKTPSQSSVAs
P35568 S531 ELM IRS1 AASAADLDNRFRKRtHsAGtsPTITHQKTPSQSSVAsIEEy
P35579 S1154 Sugiyama MYH9 KRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKK
P35613 S277 Sugiyama BSG UNQ6505/PRO21383 KITDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPG
P35637 S340 Sugiyama FUS TLS PMINLyTDRETGKLKGEAtVsFDDPPsAKAAIDWFDGKEFs
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P35998 S89 Sugiyama PSMC2 MSS1 DTGLAPPALWDLAADKQTLQsEQPLQVARCTKIINADSEDP
P36578 S365 Sugiyama RPL4 RPL1 RNHKLRVDKAAAAAAALQAKsDEKAAVAGKKPVVGKKGKKA
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P38646 S212 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P42166 S167 Sugiyama TMPO LAP2 LKLREQGtEsRsstPLPtIsssAENtRQNGsNDsDRYsDNE
P42167 S167 Sugiyama TMPO LAP2 LKLREQGTESRsstPLPTISsSAENTRQNGSNDSDRYSDNE
P42345 S1415 SIGNOR|EPSD|PSP MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1 KALHYKELEFQKGPTPAILEsLIsINNKLQQPEAAAGVLEY
P42345 S1418 PSP MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1 HYKELEFQKGPTPAILEsLIsINNKLQQPEAAAGVLEYAMK
P43034 S152 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P46776 S83 Sugiyama RPL27A LKRNQsFCPtVNLDKLWtLVsEQtRVNAAKNKtGAAPIIDV
P46776 T80 Sugiyama RPL27A HYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAKNKtGAAPI
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P47914 S142 Sugiyama RPL29 KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P49792 S1955 Sugiyama RANBP2 NUP358 GVIFGQTSSTFTFADLAKstsGEGFQFGKKDPNFKGFSGAG
P49840 Y279 Sugiyama GSK3A LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49841 Y216 Sugiyama GSK3B LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P50990 S23 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 LHVPKAPGFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTT
P51858 S165 Sugiyama HDGF HMG1L2 AKEKNEKGALKRRAGDLLEDsPKRPKEAENPEGEEKEAAtL
P52597 S285 Sugiyama HNRNPF HNRPF syCLsGMyDHRYGDsEFtVQsTTGHCVHMRGLPYKAtENDI
P53999 S118 Sugiyama SUB1 PC4 RPO2TC1 PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P55060 S342 Sugiyama CSE1L CAS XPO2 ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF
P55795 S269 Sugiyama HNRNPH2 FTP3 HNRPH2 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH
P55795 S272 Sugiyama HNRNPH2 FTP3 HNRPH2 GYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGHCVH
P55795 S285 Sugiyama HNRNPH2 FTP3 HNRPH2 NyCFsGMsDHRyGDGGssFQstTGHCVHMRGLPYRATENDI
P55795 T286 Sugiyama HNRNPH2 FTP3 HNRPH2 yCFsGMsDHRyGDGGssFQstTGHCVHMRGLPYRATENDIY
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60660 S30 Sugiyama MYL6 AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P61024 S9 Sugiyama CKS1B CKS1 PNAS-143 PNAS-16 ____________MSHKQIyysDKyDDEEFEyRHVMLPKDIA
P61247 S192 Sugiyama RPS3A FTE1 MFTL MTREVQTNDLKEVVNKLIPDsIGKDIEKACQsIyPLHDVFV
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 S9 Sugiyama RPL26 ____________MKFNPFVtsDRsKNRKRHFNAPsHIRRKI
P61313 S100 Sugiyama RPL15 EC45 TCBAP0781 tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW
P61604 S21 Sugiyama HSPE1 MAGQAFRKFLPLFDRVLVERsAAETVTKGGIMLPEKSQGKV
P61604 S64 Sugiyama HSPE1 AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S420 Sugiyama HNRNPK HNRPK GsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITItGt
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 S137 Sugiyama RPS14 PRO2640 RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______
P62424 T84 Sugiyama RPL7A SURF-3 SURF3 QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP
P62633 S121 Sugiyama CNBP RNF163 ZNF9 CGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRCG
P62633 Y120 Sugiyama CNBP RNF163 ZNF9 NCGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRC
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62857 S39 Sugiyama RPS28 GRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLL
P62857 S41 Sugiyama RPS28 tGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLLEs
P62899 T119 Sugiyama RPL31 PNKLytLVtyVPVttFKNLQtVNVDEN______________
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62917 S138 Sugiyama RPL8 EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979 S134 Sugiyama RPS27A UBA80 UBCEP1 IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P62979 T147 Sugiyama RPS27A UBA80 UBCEP1 GAGVFMAsHFDRHyCGKCCLtyCFNKPEDK___________
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63167 S21 Sugiyama DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAH
P63220 S31 Sugiyama RPS21 LYVPRKCSASNRIIGAKDHAsIQMNVAEVDKVTGRFNGQFK
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 Y99 Sugiyama YBX1 NSEP1 YB1 DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 S48 Sugiyama TUBA1B HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363 S54 Sugiyama TUBA1B GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P68363 T41 Sugiyama TUBA1B WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 Y83 Sugiyama TUBA1B PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S7 Sugiyama RPL24 ______________MKVELCsFsGyKIYPGHGRRYARTDGK
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 T83 Sugiyama RPL24 QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
P84098 S12 Sugiyama RPL19 _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
Q00613 S375 Sugiyama HSF1 HSTF1 TDtEGRPPsPPPtstPEKCLsVACLDKNELSDHLDAMDSNL
Q00653 S108 EPSD|PSP NFKB2 LYT10 PAKIEVDLVTHsDPPRAHAHsLVGKQCsELGICAVsVGPKD
Q00653 S115 EPSD|PSP NFKB2 LYT10 LVTHsDPPRAHAHsLVGKQCsELGICAVsVGPKDMTAQFNN
Q00653 S123 EPSD|PSP NFKB2 LYT10 RAHAHsLVGKQCsELGICAVsVGPKDMTAQFNNLGVLHVTK
Q00653 S866 SIGNOR|PSP NFKB2 LYT10 LLRGPETRDKLPstAEVKEDsAyGsQsVEQEAEKLGPPPEP
Q00653 S870 SIGNOR|PSP NFKB2 LYT10 PETRDKLPstAEVKEDsAyGsQsVEQEAEKLGPPPEPPGGL
Q00653 S872 ELM|EPSD|PSP NFKB2 LYT10 TRDKLPstAEVKEDsAyGsQsVEQEAEKLGPPPEPPGGLCH
Q00653 S99 EPSD|PSP NFKB2 LYT10 TVKICNYEGPAKIEVDLVTHsDPPRAHAHsLVGKQCsELGI
Q01105 S161 Sugiyama SET FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01105 S166 Sugiyama SET yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT
Q01105 S168 Sugiyama SET ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01201 S472 EPSD|PSP RELB GPFLPPSALLPDPDFFSGTVsLPGLEPPGGPDLLDDGFAYD
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q04206 S536 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP RELA NFKB3 APLGAPGLPNGLLsGDEDFSsIADMDFsALLSQISS_____
Q04864 S516 GPS6 REL VNMMTTSsDSMGETDNPRLLsMNLENPsCNsVLDPRDLRQL
Q04864 S526 GPS6 REL MGETDNPRLLsMNLENPsCNsVLDPRDLRQLHQMSSSSMSA
Q04864 S557 EPSD|PSP REL HQMSSSSMSAGANSNTTVFVsQSDAFEGSDFSCADNSMINE
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q06323 S55 Sugiyama PSME1 IFI5111 KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE
Q07021 S210 Sugiyama C1QBP GC1QBP HABP1 SF2P32 EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS
Q07157 S1063 Sugiyama TJP1 ZO1 LPYVEKQAsRDLEQPtyRyEsssytDQFsRNYEHRLRYEDR
Q07955 S182 Sugiyama SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 FVRKEDMTYAVRKLDNTKFRsHEGEtAyIRVKVDGPRsPsy
Q08209 S498 Sugiyama PPP3CA CALNA CNA RINERMPPRRDAMPsDANLNsINKALTSETNGTDSNGSNSS
Q12888 S197 Sugiyama TP53BP1 QsQDVEENTVPYEVDKEQLQsVttNsGytRLsDVDANtAIK
Q13136 S666 Sugiyama PPFIA1 LIP1 IQEEKENTEQRAEEIESRVGsGsLDNLGRFRSMssIPPYPA
Q13242 S172 Sugiyama SRSF9 SFRS9 SRP30C yLRKEDMEYALRKLDDTKFRsHEGEtsYIRVYPERstsYGY
Q13263 S784 Sugiyama TRIM28 KAP1 RNF96 TIF1B DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK
Q13283 S250 Sugiyama G3BP1 G3BP sssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGI
Q13283 S253 Sugiyama G3BP1 G3BP PAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPH
Q13442 S176 Sugiyama PDAP1 HASPP28 KKEEERKAKDDATLsGKRMQsLsLNK_______________
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13526 S105 Sugiyama PIN1 ALELINGyIQKIKSGEEDFEsLAsQFSDCSsAKARGDLGAF
Q13573 S190 Sugiyama SNW1 SKIIP SKIP KLAPAQyIRytPsQQGVAFNsGAKQRVIRMVEMQKDPMEPP
Q13601 S284 Sugiyama KRR1 HRB2 KEYtPFPPPQPESQIDKELAsGEyFLKANQKKRQKMEAIKA
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14152 S988 Sugiyama EIF3A EIF3S10 KIAA0139 PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN
Q14157 S855 Sugiyama UBAP2L KIAA0144 NICE4 ysIPFPtPttPLtGRDGsLAsNPysGDLtKFGRGDASSPAP
Q14192 S238 Sugiyama FHL2 DRAL SLIM3 AKKCAGCTNPISGLGGtKyIsFEERQWHNDCFNCKKCsLsL
Q14247 S117 Sugiyama CTTN EMS1 KsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVDQsAV
Q14247 S282 Sugiyama CTTN EMS1 QKDyKTGFGGKFGVQsERQDsAAVGFDyKEKLAKHEsQQDy
Q14320 S292 Sugiyama FAM50A DXS9928E HXC26 XAP5 ARGKsGPLFNFDVHDDVRLLsDATVEKDESHAGKVVLRSWY
Q14444 S307 Sugiyama CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 SEVESTEYVNRQFMAEtQFtsGEKEQVDEWTVETVEVVNSL
Q14498 S337 Sugiyama RBM39 HCC1 RNPC2 AGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGRL
Q14568 S50 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14677 S166 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14847 S99 Sugiyama LASP1 MLN50 ELQsQVRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsN
Q14978 S693 Sugiyama NOLC1 KIAA0035 NS5ATP13 EKTKKKRGsYRGGsIsVQVNsIKFDsE______________
Q14978 S698 Sugiyama NOLC1 KIAA0035 NS5ATP13 KRGsYRGGsIsVQVNsIKFDsE___________________
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15056 S14 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 _______MADFDtyDDRAyssFGGGRGsRGsAGGHGsRSQK
Q15080 S67 Sugiyama NCF4 SH3PXD4 TKGGSKYLIYRRYRQFHALQsKLEERFGPDSKSSALACTLP
Q15653 S19 iPTMNet NFKBIB IKBB TRIP9 __MAGVACLGKAADADEWCDsGLGsLGPDAAAPGGPGLGAE
Q15653 S23 iPTMNet NFKBIB IKBB TRIP9 GVACLGKAADADEWCDsGLGsLGPDAAAPGGPGLGAELGPG
Q15717 S304 SIGNOR|EPSD|PSP ELAVL1 HUR CKGFGFVTMTNYEEAAMAIAsLNGYRLGDKILQVsFKTNKS
Q2TAL8 S33 Sugiyama QRICH1 EYIRVKARSVPQHRMKEFLDsLASKGPEALQEFQQTATTTM
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q53EL6 S48 Sugiyama PDCD4 H731 EENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKNss
Q53EL6 S49 Sugiyama PDCD4 H731 ENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKNssR
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S408 Sugiyama HSP90AB3P HSP90BC EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
Q58FF8 S308 Sugiyama HSP90AB2P HSP90BB YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE
Q5BKZ1 S121 Sugiyama ZNF326 ZIRD SRFGGSYGGRFESSYRNsLDsFGGRNQGGssWEAPysRSKL
Q5VT52 S1180 Sugiyama RPRD2 KIAA0460 HSPC099 TGFKTAPYKERAPQFQEsVGsFRsNsFNstFEHHLPPsPLE
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q676U5 S278 EPSD|PSP ATG16L1 APG16L UNQ9393/PRO34307 RAISRAATKRLsQPAGGLLDsITNIFGRRsVssFPVPQDNV
Q6FI81 S305 Sugiyama CIAPIN1 CUA001 PRO0915 CAsCPyLGMPAFKPGEKVLLsDsNLHDA_____________
Q6PEY2 S48 Sugiyama TUBA3E HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2 S54 Sugiyama TUBA3E GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q6PEY2 T41 Sugiyama TUBA3E WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6UN15 S496 Sugiyama FIP1L1 FIP1 RHE DRERERTRERERERDHsPtPsVFNsDEERyRYREYAERGYE
Q6UN15 S500 Sugiyama FIP1L1 FIP1 RHE ERTRERERERDHsPtPsVFNsDEERyRYREYAERGYERHRA
Q6UXH1 S295 Sugiyama CRELD2 UNQ185/PRO211 KECISGYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSY
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZN18 S206 Sugiyama AEBP2 DEGYGTGGGGSSATSGGRRGsLEMssDGEPLSRMDSEDSIS
Q71U36 S48 Sugiyama TUBA1A TUBA3 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36 S54 Sugiyama TUBA1A TUBA3 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q71U36 T41 Sugiyama TUBA1A TUBA3 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 Y83 Sugiyama TUBA1A TUBA3 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q71UI9 S99 Sugiyama H2AZ2 H2AFV H2AV VKRITPRHLQLAIRGDEELDsLIKATIAGGGVIPHIHKSLI
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7RTV0 S53 Sugiyama PHF5A CDSyVRPCTLVRICDECNyGsyQGRCVICGGPGVSDAyyCK
Q7Z2W4 S364 Sugiyama ZC3HAV1 ZC3HDC2 PRO1677 PGstyLASNsTsAPNWKsLtsWtNDQGARRKtVFsPtLPAA
Q7Z3J3 S980 Sugiyama RGPD4 RGP4 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDPNFKGFSGAG
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86UE4 S306 Sugiyama MTDH AEG1 LYRIC WNEKSVKLssQIsAGEEKWNsVsPAsAGKRKtEPSAWsQDt
Q86V81 T148 Sugiyama ALYREF ALY BEF THOC4 EFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQYNG
Q86VP1 S593 SIGNOR|EPSD|PSP TAX1BP1 T6BP PRO0105 AENVKLELAEVQDNyKELKRsLENPAERKMEGQNSQsPQCF
Q86VP1 S666 SIGNOR|EPSD TAX1BP1 T6BP PRO0105 DGADGAFYPDEIQRPPVRVPsWGLEDNVVCSQPARNFsRPD
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8IWX8 S904 Sugiyama CHERP DAN26 SCAF6 KGVGVALDDPyENyRRNKsysFIARMKARDECK________
Q8N3F0 S58 SIGNOR|EPSD|PSP MTURN C7orf41 GVSFYVLCPDNGCGDNFHVWsESEDCLPFLQLAQDYISSCG
Q8NBJ7 S256 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG
Q8NFH8 S631 Sugiyama REPS2 POB1 AIQTAIRKNKEANAVLARLNsELQQQLKEVHQERIALENQL
Q8NHW5 S307 Sugiyama RPLP0P6 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8WU90 S351 Sugiyama ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 DIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLsEAs
Q8WUD4 S152 Sugiyama CCDC12 QRAIAELIRERLKGQEDsLAsAVDAATEQKtCDsD______
Q8WWI1 S704 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 KKRLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEM
Q8WWI1 S706 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 RLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEMQK
Q8WXX5 S215 Sugiyama DNAJC9 EEAKEAEMSRKELGLDEGVDsLKAAIQSRQKDRQKEMDNFL
Q92733 S278 Sugiyama PRCC TPRC KQItQEEDDsDEEVAPENFFsLPEKAEPPGVEPYPYPIPTV
Q92793 S1382 SIGNOR|EPSD|PSP CREBBP CBP VASSDKTVEVKPGMKSRFVDsGEMsESFPYRTKALFAFEEI
Q92793 S1386 SIGNOR|EPSD|PSP CREBBP CBP DKTVEVKPGMKSRFVDsGEMsESFPYRTKALFAFEEIDGVD
Q92804 S289 Sugiyama TAF15 RBP56 TAF2N PMINLYTDKDTGKPKGEAtVsFDDPPsAKAAIDWFDGKEFH
Q92890 S294 Sugiyama UFD1 UFD1L SRPLVKKVEEDEAGGRFVAFsGEGQsLRKKGRKP_______
Q92905 S201 SIGNOR|PSP COPS5 CSN5 JAB1 VNLGAFRTYPKGYKPPDEGPsEyQtIPLNKIEDFGVHCKQY
Q92905 T205 SIGNOR|PSP COPS5 CSN5 JAB1 AFRTYPKGYKPPDEGPsEyQtIPLNKIEDFGVHCKQYYALE
Q92934 S25 SIGNOR BAD BBC6 BCL2L8 PEFEPSEQEDSSSAERGLGPsPAGDGPsGsGKHHRQAPGLL
Q92945 S193 Sugiyama KHSRP FUBP2 DSGCKVQIsPDsGGLPERsVsLtGAPEsVQKAKMMLDDIVS
Q96AE4 S52 Sugiyama FUBP1 KDALQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQ
Q96AE4 S55 Sugiyama FUBP1 LQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQPDA
Q96C01 S135 Sugiyama FAM136A VDDHMHLIPTMTKKMKEALLsIGK_________________
Q96D71 S767 Sugiyama REPS1 AIQAsIRRNKETNTVLARLNsELQQQLKDVLEERISLEVQL
Q96HE7 S143 Sugiyama ERO1A ERO1L UNQ434/PRO865 EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD
Q99558 S814 PSP MAP3K14 NIK ILSCLSIDSLSLSDDSEKNPsKAsQSsRDTLSsGVHsWSSQ
Q99558 S817 PSP MAP3K14 NIK CLSIDSLSLSDDSEKNPsKAsQSsRDTLSsGVHsWSSQAEA
Q99558 S820 PSP MAP3K14 NIK IDSLSLSDDSEKNPsKAsQSsRDTLSsGVHsWSSQAEARSS
Q99558 T559 SIGNOR MAP3K14 NIK VCLQPDGLGKSLLTGDYIPGtETHMAPEVVLGRSCDAKVDV
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99666 S979 Sugiyama RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
Q9BQE3 S439 Sugiyama TUBA1C TUBA6 SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BQE3 S48 Sugiyama TUBA1C TUBA6 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3 S54 Sugiyama TUBA1C TUBA6 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q9BQE3 T41 Sugiyama TUBA1C TUBA6 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 Y83 Sugiyama TUBA1C TUBA6 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BR76 S391 Sugiyama CORO1B EAALEAEEWVSGRDADPILIsLREAYVPSKQRDLKISRRNV
Q9BTC0 S352 Sugiyama DIDO1 C20orf158 DATF1 KIAA0333 TADQQEAKWRPGDADGTDCTsIGtIEQKSSEDQGIKGRIEK
Q9BUZ4 S426 SIGNOR|EPSD|PSP TRAF4 CART1 MLN62 RNF83 ETFHPDPNWKNFQKPGtWRGsLDEsSLGFGYPKFISHQDIR
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BXH1 S10 EPSD|PSP BBC3 PUMA ___________MARARQEGSsPEPVEGLARDGPRPFPLGRL
Q9BY44 S526 Sugiyama EIF2A CDA02 MSTP004 MSTP089 sPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKLKA
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BZI7 S166 Sugiyama UPF3B RENT3B UPF3X KRDTKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIE
Q9C0C2 S920 Sugiyama TNKS1BP1 KIAA1741 TAB182 QDANEQGQDLGKRDHHGRyssQDADEQDWEFQKRDVsLGTy
Q9C0C7 S1043 SIGNOR|PSP AMBRA1 DCAF3 KIAA1736 GLAYGTNKGDLVICRPEALNsGVEYYWDQLNETVFTVHSNS
Q9GZT3 S15 Sugiyama SLIRP C14orf156 DC23 DC50 PD04872 ______MAASAARGAAALRRsINQPVAFVRRIPWTAASSQL
Q9H0L4 S344 Sugiyama CSTF2T KIAA0689 LPPRGLLGDAPNDPRGGtLLsVtGEVEPRGYLGPPHQGPPM
Q9H3Q1 S312 Sugiyama CDC42EP4 BORG4 CEP4 sPGsARSMGSHTTRDSSsLssCtsGILEERsPAFRGPDRAR
Q9H6F5 S136 Sugiyama CCDC86 CYCLON CQPKPSEEAPKCsQDQGVLAsELAQNKEELtPGAPQHQLPP
Q9NP61 S370 Sugiyama ARFGAP3 ARFGAP1 FTSSSSYFDEPVELRsssFssWDDssDSyWKKETSKDTETV
Q9NPA8 S100 Sugiyama ENY2 DC6 PDSVKKELLQRIRTFLAQHAsL___________________
Q9NQC7 S418 SIGNOR CYLD CYLD1 KIAA0849 HSPC057 ssPPLQPPPVNSLTTENRFHsLPFsLtKMPNTNGsIGHsPL
Q9NQC7 S422 SIGNOR CYLD CYLD1 KIAA0849 HSPC057 LQPPPVNSLTTENRFHsLPFsLtKMPNTNGsIGHsPLsLsA
Q9NQC7 S432 SIGNOR CYLD CYLD1 KIAA0849 HSPC057 TENRFHsLPFsLtKMPNTNGsIGHsPLsLsAQsVMEELNTA
Q9NQC7 S436 SIGNOR CYLD CYLD1 KIAA0849 HSPC057 FHsLPFsLtKMPNTNGsIGHsPLsLsAQsVMEELNTAPVQE
Q9NQC7 S439 SIGNOR CYLD CYLD1 KIAA0849 HSPC057 LPFsLtKMPNTNGsIGHsPLsLsAQsVMEELNTAPVQESPP
Q9NQC7 S441 SIGNOR CYLD CYLD1 KIAA0849 HSPC057 FsLtKMPNTNGsIGHsPLsLsAQsVMEELNTAPVQESPPLA
Q9NQC7 S444 SIGNOR CYLD CYLD1 KIAA0849 HSPC057 tKMPNTNGsIGHsPLsLsAQsVMEELNTAPVQESPPLAMPP
Q9NRA8 S353 Sugiyama EIF4ENIF1 SASRFSRWFSNPsRsGsRsssLGstPHEELERLAGLEQAIL
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NVS9 S55 Sugiyama PNPO GPMRKsYRGDREAFEETHLTsLDPVKQFAAWFEEAVQCPDI
Q9NYF8 S198 Sugiyama BCLAF1 BTF KIAA0164 PLKsKsQEEPKDtFEHDPsEsIDEFNKssAtsGDIWPGLsA
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UII2 S39 Sugiyama ATP5IF1 ATPI ATPIF1 TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF
Q9UKS6 S327 Sugiyama PACSIN3 QRtIsRKEKGGRsPDEVtLtsIVPTRDGTAPPPQsPGsPGt
Q9UNX3 S9 Sugiyama RPL26L1 RPL26P1 ____________MKFNPFVtsDRsKNRKRHFNAPSHVRRKI
Q9UNZ2 S176 Sugiyama NSFL1C UBXN2C RLGAAPEEEsAyVAGEKRQHssQDVHVVLKLWKsGFsLDNG
Q9UNZ2 S74 Sugiyama NSFL1C UBXN2C SQATPssVsRGTAPSDNRVtsFRDLIHDQDEDEEEEEGQRF
Q9UPQ0 S204 Sugiyama LIMCH1 KIAA1102 DsERsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVVLRG
Q9UQ35 S854 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sHSsssPHPKVKsGtPPRQGsItsPQANEQsVtPQRRsCFE
Q9UQ35 S875 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ItsPQANEQsVtPQRRsCFEssPDPELKsRtPsRHsCsGss
Q9Y243 S472 Sugiyama AKT3 PKBG YDEDGMDCMDNERRPHFPQFsysAsGRE_____________
Q9Y243 S474 Sugiyama AKT3 PKBG EDGMDCMDNERRPHFPQFsysAsGRE_______________
Q9Y261 S107 SIGNOR|EPSD|PSP FOXA2 HNF3B TCF3B MAGMGGSAGAAGVAGMGPHLsPSLsPLGGQAAGAMGGLAPY
Q9Y261 S111 SIGNOR|EPSD|PSP FOXA2 HNF3B TCF3B GGSAGAAGVAGMGPHLsPSLsPLGGQAAGAMGGLAPYANMN
Q9Y266 T283 Sugiyama NUDC EINtKKINPENsKLsDLDsEtRsMVEKMMYDQRQKsMGLPt
Q9Y2B0 S115 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF
Q9Y2B0 S127 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 RVVGRNGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDE
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2T7 S137 Sugiyama YBX2 CSDA3 MSY2 EDVFVHQtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEA
Q9Y3B8 S203 Sugiyama REXO2 SFN SMFN CGI-114 EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK
Q9Y3U8 S91 Sugiyama RPL36 KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y450 S67 Sugiyama HBS1L HBS1 KIAA1038 KPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCLDH
Q9Y4H2 S304 ELM IRS2 HETILEAMKALKELFEFRPRsKsQssGssATHPISVPGARR
Q9Y4H2 S306 ELM IRS2 TILEAMKALKELFEFRPRsKsQssGssATHPISVPGARRHH
Q9Y4H2 S384 ELM IRS2 AsEGDGGAAAGAAAAGARPVsVAGsPLsPGPVRAPLsRSHt
Q9Y4H2 S388 ELM IRS2 DGGAAAGAAAAGARPVsVAGsPLsPGPVRAPLsRSHtLsGG
Q9Y4H2 S577 ELM IRS2 RRVsGDAAQDLDRGLRKRtYsLtTPARQRPVPQPssAsLDE
Q9Y5L4 S57 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y618 S2407 SIGNOR|PSP NCOR2 CTG26 SDHTLTSPGGGGKAKVSGRPsSRKAKsPAPGLASGDRPPsV
Q9Y620 S64 Sugiyama RAD54B FEGVAINNTFLPSQNDLRICsLNLPSEESTREINNRDNCSG
Q9Y6K9 S376 SIGNOR IKBKG FIP3 NEMO MRKRHVEVSQAPLPPAPAyLssPLALPsQRRsPPEEPPDFC
Q9Y6K9 S43 SIGNOR IKBKG FIP3 NEMO DQDVLGEEsPLGKPAMLHLPsEQGAPETLQRCLEENQELRD
Q9Y6K9 S68 SIGNOR IKBKG FIP3 NEMO PETLQRCLEENQELRDAIRQsNQILRERCEELLHFQAsQRE
Q9Y6K9 S85 SIGNOR IKBKG FIP3 NEMO IRQsNQILRERCEELLHFQAsQREEKEFLMCKFQEARKLVE
Q9Y6Q9 S857 SIGNOR|iPTMNet|EPSD|PSP NCOA3 AIB1 BHLHE42 RAC3 TRAM1 LGLKSSQSVQSIRPPYNRAVsLDsPVsVGssPPVKNISAFP
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.043243e-11 10.517 1 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 4.249020e-08 7.372 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 4.495452e-07 6.347 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 2.556197e-06 5.592 0 0
Signaling by ALK in cancer R-HSA-9700206 2.556197e-06 5.592 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 5.100211e-06 5.292 0 0
Cell Cycle R-HSA-1640170 5.366594e-06 5.270 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.086783e-05 4.964 0 0
Cell Cycle, Mitotic R-HSA-69278 3.083024e-05 4.511 0 0
Apoptotic execution phase R-HSA-75153 4.920856e-05 4.308 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 5.587315e-05 4.253 0 0
Chromatin organization R-HSA-4839726 5.904956e-05 4.229 0 0
Chromatin modifying enzymes R-HSA-3247509 9.605653e-05 4.017 0 0
mRNA Splicing R-HSA-72172 1.348987e-04 3.870 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.489400e-04 3.827 0 0
Mitotic Prometaphase R-HSA-68877 1.535451e-04 3.814 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.693994e-04 3.771 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 2.326776e-04 3.633 1 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 2.534329e-04 3.596 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 2.640991e-04 3.578 0 0
Death Receptor Signaling R-HSA-73887 2.870226e-04 3.542 1 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.870226e-04 3.542 1 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.165666e-04 3.500 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 3.232816e-04 3.490 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.081565e-04 3.511 0 0
M Phase R-HSA-68886 3.133689e-04 3.504 0 0
mRNA 3'-end processing R-HSA-72187 5.023806e-04 3.299 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 5.260756e-04 3.279 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 5.652298e-04 3.248 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 7.044648e-04 3.152 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 7.510950e-04 3.124 0 0
Signaling by Hippo R-HSA-2028269 9.122474e-04 3.040 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.022386e-03 2.990 0 0
Signaling by FGFR in disease R-HSA-1226099 1.067114e-03 2.972 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 1.197834e-03 2.922 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.185085e-03 2.926 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 1.266752e-03 2.897 0 0
Post NMDA receptor activation events R-HSA-438064 1.354893e-03 2.868 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.402335e-03 2.853 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.629555e-03 2.788 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.537578e-03 2.813 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 1.567089e-03 2.805 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.590155e-03 2.799 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.604996e-03 2.795 0 0
Signaling by TGFB family members R-HSA-9006936 1.872191e-03 2.728 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 2.001769e-03 2.699 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 2.135104e-03 2.671 1 1
RNA Polymerase II Transcription Termination R-HSA-73856 2.190491e-03 2.659 0 0
ALK mutants bind TKIs R-HSA-9700645 2.409630e-03 2.618 0 0
Signaling by VEGF R-HSA-194138 2.406426e-03 2.619 0 0
Signal Transduction R-HSA-162582 2.690338e-03 2.570 1 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.841350e-03 2.546 0 0
Cell-Cell communication R-HSA-1500931 3.066789e-03 2.513 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 3.518541e-03 2.454 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 3.554227e-03 2.449 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 3.765951e-03 2.424 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 4.247745e-03 2.372 0 0
Gene expression (Transcription) R-HSA-74160 4.187811e-03 2.378 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 4.536704e-03 2.343 0 0
Regulation of PTEN gene transcription R-HSA-8943724 4.470764e-03 2.350 0 0
Ephrin signaling R-HSA-3928664 4.559561e-03 2.341 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 4.559561e-03 2.341 1 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 4.704970e-03 2.327 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 4.741041e-03 2.324 0 0
Mitotic Prophase R-HSA-68875 4.911938e-03 2.309 0 0
Cellular response to heat stress R-HSA-3371556 5.383321e-03 2.269 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 5.450691e-03 2.264 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 5.450691e-03 2.264 0 0
ESR-mediated signaling R-HSA-8939211 5.671245e-03 2.246 0 0
EPH-Ephrin signaling R-HSA-2682334 5.722498e-03 2.242 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.729672e-03 2.242 1 1
Cellular Senescence R-HSA-2559583 5.755425e-03 2.240 0 0
L1CAM interactions R-HSA-373760 6.364549e-03 2.196 0 0
Nuclear import of Rev protein R-HSA-180746 6.771455e-03 2.169 0 0
RAF activation R-HSA-5673000 6.771455e-03 2.169 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 6.988342e-03 2.156 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 6.996726e-03 2.155 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 7.056138e-03 2.151 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 7.620241e-03 2.118 0 0
Estrogen-dependent gene expression R-HSA-9018519 7.676168e-03 2.115 0 0
Nervous system development R-HSA-9675108 7.759053e-03 2.110 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 8.000358e-03 2.097 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 8.000358e-03 2.097 0 0
TGFBR3 expression R-HSA-9839394 8.452329e-03 2.073 0 0
Intracellular signaling by second messengers R-HSA-9006925 8.474025e-03 2.072 1 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 8.531454e-03 2.069 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.027412e-02 1.988 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.027412e-02 1.988 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.027412e-02 1.988 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.027412e-02 1.988 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.027412e-02 1.988 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.027412e-02 1.988 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.027412e-02 1.988 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.027412e-02 1.988 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.027412e-02 1.988 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.027412e-02 1.988 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.027412e-02 1.988 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 9.106427e-03 2.041 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 9.106427e-03 2.041 0 0
Recycling pathway of L1 R-HSA-437239 9.392439e-03 2.027 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.076750e-02 1.968 0 0
COPI-mediated anterograde transport R-HSA-6807878 9.455683e-03 2.024 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 9.455683e-03 2.024 0 0
Signaling by FGFR1 in disease R-HSA-5655302 9.498106e-03 2.022 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.028096e-02 1.988 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.076750e-02 1.968 0 0
PKR-mediated signaling R-HSA-9833482 1.057330e-02 1.976 1 1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 1.102235e-02 1.958 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 1.129202e-02 1.947 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.235008e-02 1.908 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.273296e-02 1.895 0 0
FGFR1 mutant receptor activation R-HSA-1839124 1.273296e-02 1.895 0 0
Protein ubiquitination R-HSA-8852135 1.255220e-02 1.901 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 1.253141e-02 1.902 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 1.281793e-02 1.892 0 0
Signaling by EGFR R-HSA-177929 1.337036e-02 1.874 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 1.253141e-02 1.902 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 1.273296e-02 1.895 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 1.253141e-02 1.902 0 0
Axon guidance R-HSA-422475 1.188622e-02 1.925 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 1.211274e-02 1.917 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 1.273296e-02 1.895 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.318819e-02 1.880 1 1
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 1.337036e-02 1.874 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.281031e-02 1.892 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.255220e-02 1.901 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.363214e-02 1.865 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.373006e-02 1.862 1 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.507875e-02 1.822 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.461020e-02 1.835 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.423618e-02 1.847 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.423618e-02 1.847 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.448886e-02 1.839 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.551736e-02 1.809 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 1.507875e-02 1.822 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 1.482712e-02 1.829 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.490907e-02 1.827 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.507875e-02 1.822 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.482712e-02 1.829 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.589804e-02 1.799 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 1.589804e-02 1.799 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.607186e-02 1.794 0 0
Deubiquitination R-HSA-5688426 1.629125e-02 1.788 0 0
Cell junction organization R-HSA-446728 1.630661e-02 1.788 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 1.725720e-02 1.763 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.761097e-02 1.754 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.768970e-02 1.752 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 1.851688e-02 1.732 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 1.852793e-02 1.732 0 0
Diseases of Telomere Maintenance R-HSA-9673013 2.097709e-02 1.678 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 2.097709e-02 1.678 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 2.097709e-02 1.678 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 2.097709e-02 1.678 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 2.097709e-02 1.678 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 2.009416e-02 1.697 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.007545e-02 1.697 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.973048e-02 1.705 0 0
Signalling to ERKs R-HSA-187687 2.007545e-02 1.697 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.009416e-02 1.697 0 0
Apoptosis R-HSA-109581 1.917701e-02 1.717 0 0
Interleukin-37 signaling R-HSA-9008059 2.023779e-02 1.694 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.125747e-02 1.672 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 2.249565e-02 1.648 0 0
Formation of definitive endoderm R-HSA-9823730 2.249565e-02 1.648 0 0
Downstream signal transduction R-HSA-186763 2.357275e-02 1.628 0 0
Prolonged ERK activation events R-HSA-169893 2.498488e-02 1.602 0 0
MTOR signalling R-HSA-165159 2.528829e-02 1.597 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.559454e-02 1.592 1 0
tRNA processing in the nucleus R-HSA-6784531 2.610460e-02 1.583 0 0
NF-kB is activated and signals survival R-HSA-209560 2.662566e-02 1.575 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.938886e-02 1.532 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 2.938886e-02 1.532 1 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.644675e-02 1.578 0 0
Signaling by SCF-KIT R-HSA-1433557 2.857916e-02 1.544 0 0
Semaphorin interactions R-HSA-373755 2.888941e-02 1.539 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 2.644090e-02 1.578 0 0
Gap junction trafficking and regulation R-HSA-157858 2.691725e-02 1.570 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 2.759033e-02 1.559 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 2.954052e-02 1.530 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 2.954052e-02 1.530 0 0
Metabolism of RNA R-HSA-8953854 2.958196e-02 1.529 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 2.970366e-02 1.527 0 0
PI3K Cascade R-HSA-109704 3.012563e-02 1.521 0 0
IRS-mediated signalling R-HSA-112399 3.119644e-02 1.506 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 3.138368e-02 1.503 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 3.217016e-02 1.493 0 0
Oncogenic MAPK signaling R-HSA-6802957 3.235368e-02 1.490 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 3.369112e-02 1.472 0 0
Repression of WNT target genes R-HSA-4641265 3.369112e-02 1.472 0 0
Notch-HLH transcription pathway R-HSA-350054 3.781874e-02 1.422 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 3.606198e-02 1.443 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 3.735229e-02 1.428 0 0
Aggrephagy R-HSA-9646399 3.851152e-02 1.414 0 0
mTORC1-mediated signalling R-HSA-166208 3.781874e-02 1.422 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 3.437740e-02 1.464 0 0
Mitotic Anaphase R-HSA-68882 3.521157e-02 1.453 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.703336e-02 1.431 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 3.850023e-02 1.415 0 0
Inositol phosphate metabolism R-HSA-1483249 3.829155e-02 1.417 0 0
G2/M Transition R-HSA-69275 3.477854e-02 1.459 0 0
RNA Polymerase II Transcription R-HSA-73857 3.656110e-02 1.437 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 3.781874e-02 1.422 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.851152e-02 1.414 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 3.864276e-02 1.413 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 3.864276e-02 1.413 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.874778e-02 1.412 0 0
Adherens junctions interactions R-HSA-418990 3.892596e-02 1.410 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 3.937001e-02 1.405 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.944069e-02 1.404 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.944069e-02 1.404 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 4.332936e-02 1.363 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 4.332936e-02 1.363 0 0
Calcineurin activates NFAT R-HSA-2025928 4.525717e-02 1.344 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 4.083240e-02 1.389 0 0
Signaling by RAS mutants R-HSA-6802949 4.027704e-02 1.395 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 4.027704e-02 1.395 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 4.027704e-02 1.395 0 0
Signaling downstream of RAS mutants R-HSA-9649948 4.027704e-02 1.395 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.139005e-02 1.383 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 4.614336e-02 1.336 0 0
Centrosome maturation R-HSA-380287 4.587135e-02 1.338 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 4.326286e-02 1.364 0 0
Interleukin-6 signaling R-HSA-1059683 4.181847e-02 1.379 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 4.614336e-02 1.336 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 4.612368e-02 1.336 0 0
Unwinding of DNA R-HSA-176974 4.525717e-02 1.344 0 0
Regulated proteolysis of p75NTR R-HSA-193692 4.525717e-02 1.344 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.027704e-02 1.395 0 0
Programmed Cell Death R-HSA-5357801 4.416283e-02 1.355 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 4.415129e-02 1.355 1 1
Signaling by TGFBR3 R-HSA-9839373 4.027704e-02 1.395 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 4.419638e-02 1.355 0 0
Gap junction assembly R-HSA-190861 4.083240e-02 1.389 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 4.326286e-02 1.364 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 4.620864e-02 1.335 1 1
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 4.824002e-02 1.317 0 0
Signaling by RAF1 mutants R-HSA-9656223 4.839766e-02 1.315 0 0
Heme signaling R-HSA-9707616 5.051923e-02 1.297 0 0
Signaling by PDGF R-HSA-186797 5.051923e-02 1.297 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 5.103085e-02 1.292 0 0
Signal regulatory protein family interactions R-HSA-391160 5.103085e-02 1.292 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 5.112852e-02 1.291 1 1
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 5.112852e-02 1.291 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 5.112852e-02 1.291 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 5.199629e-02 1.284 0 0
FLT3 signaling in disease R-HSA-9682385 5.203598e-02 1.284 0 0
DNA Repair R-HSA-73894 5.204657e-02 1.284 0 0
STING mediated induction of host immune responses R-HSA-1834941 5.220267e-02 1.282 0 0
Separation of Sister Chromatids R-HSA-2467813 5.274896e-02 1.278 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 5.392566e-02 1.268 0 0
TNF signaling R-HSA-75893 5.530371e-02 1.257 1 0
NRAGE signals death through JNK R-HSA-193648 5.530371e-02 1.257 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 5.637004e-02 1.249 0 0
Regulation of CDH11 function R-HSA-9762292 5.734411e-02 1.242 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 5.876322e-02 1.231 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 5.977267e-02 1.223 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 7.098316e-02 1.149 0 0
Negative regulation of MET activity R-HSA-6807004 6.103653e-02 1.214 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 6.103653e-02 1.214 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 7.070260e-02 1.151 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 6.614937e-02 1.179 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 6.540329e-02 1.184 0 0
Signaling by FGFR2 in disease R-HSA-5655253 6.052251e-02 1.218 0 0
DCC mediated attractive signaling R-HSA-418885 6.133751e-02 1.212 0 0
Signal transduction by L1 R-HSA-445144 6.103653e-02 1.214 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 5.940865e-02 1.226 0 0
p75NTR signals via NF-kB R-HSA-193639 6.133751e-02 1.212 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 6.706358e-02 1.174 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 6.955907e-02 1.158 0 0
IGF1R signaling cascade R-HSA-2428924 6.015368e-02 1.221 0 0
Insulin receptor signalling cascade R-HSA-74751 6.015368e-02 1.221 0 0
Regulation of TP53 Activity R-HSA-5633007 6.419342e-02 1.193 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 6.540329e-02 1.184 0 0
Cellular responses to stimuli R-HSA-8953897 6.126397e-02 1.213 1 0
Cell-extracellular matrix interactions R-HSA-446353 6.133751e-02 1.212 0 0
Gap junction trafficking R-HSA-190828 6.619271e-02 1.179 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 5.985511e-02 1.223 0 0
ChREBP activates metabolic gene expression R-HSA-163765 7.098316e-02 1.149 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 7.053410e-02 1.152 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 7.231299e-02 1.141 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 7.382271e-02 1.132 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 7.603319e-02 1.119 1 1
Signaling by NTRKs R-HSA-166520 7.709718e-02 1.113 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 7.829916e-02 1.106 0 0
Kinesins R-HSA-983189 7.829916e-02 1.106 0 0
CREB phosphorylation R-HSA-199920 7.869174e-02 1.104 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 7.869174e-02 1.104 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 7.881938e-02 1.103 1 0
Epigenetic regulation of gene expression R-HSA-212165 7.943578e-02 1.100 0 0
Regulation of TNFR1 signaling R-HSA-5357905 8.011117e-02 1.096 1 1
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 8.119820e-02 1.090 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 8.119820e-02 1.090 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 8.119820e-02 1.090 0 0
HIV Life Cycle R-HSA-162587 8.177969e-02 1.087 0 0
Membrane Trafficking R-HSA-199991 8.257398e-02 1.083 0 0
Cell-cell junction organization R-HSA-421270 8.285725e-02 1.082 0 0
Deletions in the AXIN1 gene destabilize the destruction complex R-HSA-5467345 1.043175e-01 0.982 0 0
Deletions in the AMER1 gene destabilize the destruction complex R-HSA-5467343 1.043175e-01 0.982 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.043175e-01 0.982 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.043175e-01 0.982 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 9.986158e-02 1.001 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 9.986158e-02 1.001 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 9.986158e-02 1.001 0 0
Signaling by AMER1 mutants R-HSA-4839748 8.612192e-02 1.065 0 0
Signaling by AXIN mutants R-HSA-4839735 8.612192e-02 1.065 0 0
Signaling by GSK3beta mutants R-HSA-5339716 8.612192e-02 1.065 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.026868e-01 0.988 1 1
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 1.026868e-01 0.988 0 0
Regulation of IFNG signaling R-HSA-877312 1.026868e-01 0.988 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 1.026868e-01 0.988 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 1.026868e-01 0.988 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 1.026868e-01 0.988 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 1.026868e-01 0.988 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 8.520468e-02 1.070 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 9.872023e-02 1.006 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 9.872023e-02 1.006 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 9.872023e-02 1.006 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 9.251357e-02 1.034 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 8.567105e-02 1.067 0 0
HIV elongation arrest and recovery R-HSA-167287 8.567105e-02 1.067 0 0
Pausing and recovery of HIV elongation R-HSA-167290 8.567105e-02 1.067 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.713794e-02 1.013 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 1.017263e-01 0.993 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.970621e-02 1.001 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.041237e-01 0.982 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 9.251357e-02 1.034 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 8.821078e-02 1.054 0 0
Oncogene Induced Senescence R-HSA-2559585 9.713794e-02 1.013 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 8.520468e-02 1.070 0 0
PTEN Regulation R-HSA-6807070 1.024640e-01 0.989 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 8.771329e-02 1.057 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 9.393261e-02 1.027 0 0
Cellular responses to stress R-HSA-2262752 8.918970e-02 1.050 0 0
Viral Messenger RNA Synthesis R-HSA-168325 8.487117e-02 1.071 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 8.821078e-02 1.054 0 0
Uptake and function of anthrax toxins R-HSA-5210891 9.872023e-02 1.006 0 0
Signaling by KIT in disease R-HSA-9669938 9.251357e-02 1.034 0 0
Signaling by FGFR1 amplification mutants R-HSA-1839120 1.059688e-01 0.975 0 0
Signaling by FGFR2 amplification mutants R-HSA-2023837 1.059688e-01 0.975 0 0
MET activates PTPN11 R-HSA-8865999 1.059688e-01 0.975 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 1.060181e-01 0.975 0 0
Ca-dependent events R-HSA-111996 1.060181e-01 0.975 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 1.069252e-01 0.971 0 0
Activation of the pre-replicative complex R-HSA-68962 1.069252e-01 0.971 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 1.071125e-01 0.970 0 0
RNA Polymerase III Transcription R-HSA-74158 1.071125e-01 0.970 0 0
FGFR2 mutant receptor activation R-HSA-1839126 1.071125e-01 0.970 0 0
Regulation of TP53 Degradation R-HSA-6804757 1.071125e-01 0.970 0 0
Calmodulin induced events R-HSA-111933 1.071125e-01 0.970 0 0
CaM pathway R-HSA-111997 1.071125e-01 0.970 0 0
RET signaling R-HSA-8853659 1.071125e-01 0.970 0 0
Regulation of gap junction activity R-HSA-191650 1.423447e-01 0.847 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 1.423447e-01 0.847 0 0
Signaling by MAP2K mutants R-HSA-9652169 1.423447e-01 0.847 0 0
Type I hemidesmosome assembly R-HSA-446107 1.230282e-01 0.910 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 1.230282e-01 0.910 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.230282e-01 0.910 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 1.230282e-01 0.910 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.230282e-01 0.910 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.205869e-01 0.919 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 1.397175e-01 0.855 1 1
FOXO-mediated transcription of cell death genes R-HSA-9614657 1.132423e-01 0.946 0 0
Regulation of signaling by CBL R-HSA-912631 1.287228e-01 0.890 0 0
Trafficking of AMPA receptors R-HSA-399719 1.185175e-01 0.926 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.435435e-01 0.843 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 1.222034e-01 0.913 1 1
Meiotic synapsis R-HSA-1221632 1.418905e-01 0.848 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.418905e-01 0.848 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.105229e-01 0.957 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.365597e-01 0.865 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.365597e-01 0.865 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.365597e-01 0.865 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.365597e-01 0.865 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.365597e-01 0.865 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.343737e-01 0.872 0 0
Signaling by NOTCH1 R-HSA-1980143 1.429108e-01 0.845 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 1.205869e-01 0.919 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 1.093359e-01 0.961 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 1.230282e-01 0.910 0 0
HSF1-dependent transactivation R-HSA-3371571 1.222034e-01 0.913 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.273112e-01 0.895 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 1.435435e-01 0.843 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.311831e-01 0.882 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.311831e-01 0.882 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.311831e-01 0.882 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.261274e-01 0.899 0 0
Formation of axial mesoderm R-HSA-9796292 1.205869e-01 0.919 0 0
Signaling by WNT in cancer R-HSA-4791275 1.307309e-01 0.884 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.318499e-01 0.880 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.230282e-01 0.910 0 0
Long-term potentiation R-HSA-9620244 1.311831e-01 0.882 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.402333e-01 0.853 0 0
Frs2-mediated activation R-HSA-170968 1.205869e-01 0.919 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.185175e-01 0.926 0 0
DNA strand elongation R-HSA-69190 1.307309e-01 0.884 0 0
Activation of ATR in response to replication stress R-HSA-176187 1.435435e-01 0.843 0 0
GAB1 signalosome R-HSA-180292 1.132423e-01 0.946 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 1.185175e-01 0.926 0 0
Selective autophagy R-HSA-9663891 1.234442e-01 0.909 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.099995e-01 0.959 1 0
Response of endothelial cells to shear stress R-HSA-9860931 1.408509e-01 0.851 1 0
Co-inhibition by PD-1 R-HSA-389948 1.363722e-01 0.865 0 0
TBC/RABGAPs R-HSA-8854214 1.156282e-01 0.937 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.266911e-01 0.897 0 0
Macroautophagy R-HSA-1632852 1.128005e-01 0.948 0 0
Signaling by ERBB2 R-HSA-1227986 1.365597e-01 0.865 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.335929e-01 0.874 0 0
DAG and IP3 signaling R-HSA-1489509 1.362233e-01 0.866 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.132423e-01 0.946 0 0
Cilium Assembly R-HSA-5617833 1.270362e-01 0.896 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.174917e-01 0.930 0 0
MTF1 activates gene expression R-HSA-5660489 1.423447e-01 0.847 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 1.423447e-01 0.847 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.266911e-01 0.897 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.435435e-01 0.843 0 0
Regulation of necroptotic cell death R-HSA-5675482 1.435435e-01 0.843 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 1.205869e-01 0.919 0 0
snRNP Assembly R-HSA-191859 1.273112e-01 0.895 0 0
Metabolism of non-coding RNA R-HSA-194441 1.273112e-01 0.895 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 1.435435e-01 0.843 0 0
Nephrin family interactions R-HSA-373753 1.451058e-01 0.838 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 1.455531e-01 0.837 0 0
Myogenesis R-HSA-525793 1.455531e-01 0.837 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 1.479222e-01 0.830 0 0
MAPK1 (ERK2) activation R-HSA-112411 1.479222e-01 0.830 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.479222e-01 0.830 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.479222e-01 0.830 0 0
Interleukin-1 processing R-HSA-448706 1.479222e-01 0.830 0 0
Nucleotide Excision Repair R-HSA-5696398 1.558632e-01 0.807 0 0
Resolution of D-Loop Structures R-HSA-5693537 1.569305e-01 0.804 0 0
Autophagy R-HSA-9612973 1.593790e-01 0.798 0 0
Erythropoietin activates RAS R-HSA-9027284 1.599635e-01 0.796 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.599635e-01 0.796 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 1.599635e-01 0.796 0 0
Formation of the anterior neural plate R-HSA-9823739 1.599635e-01 0.796 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.606032e-01 0.794 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.606032e-01 0.794 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.606032e-01 0.794 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 1.606032e-01 0.794 0 0
G alpha (12/13) signalling events R-HSA-416482 1.608364e-01 0.794 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.621949e-01 0.790 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.621949e-01 0.790 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.623286e-01 0.790 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.623286e-01 0.790 0 0
Basigin interactions R-HSA-210991 1.623286e-01 0.790 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.977583e-01 0.704 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 1.977583e-01 0.704 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 1.977583e-01 0.704 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.977583e-01 0.704 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.977583e-01 0.704 0 0
Signaling by FGFR2 fusions R-HSA-8853333 2.814559e-01 0.551 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 2.814559e-01 0.551 0 0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027 2.814559e-01 0.551 1 1
Defective SLC26A2 causes chondrodysplasias R-HSA-3560792 2.814559e-01 0.551 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 2.814559e-01 0.551 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.814559e-01 0.551 0 0
IKBKB deficiency causes SCID R-HSA-5602636 2.814559e-01 0.551 1 1
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) R-HSA-5619039 2.814559e-01 0.551 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 1.808630e-01 0.743 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.206816e-01 0.656 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 3.564258e-01 0.448 0 0
Signaling by RAS GAP mutants R-HSA-9753510 3.564258e-01 0.448 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 3.564258e-01 0.448 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 3.564258e-01 0.448 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.742694e-01 0.759 0 0
MAPK3 (ERK1) activation R-HSA-110056 1.742694e-01 0.759 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 2.611105e-01 0.583 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.611105e-01 0.583 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 2.611105e-01 0.583 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 2.017985e-01 0.695 0 0
Signaling by APC mutants R-HSA-4839744 2.017985e-01 0.695 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 2.017985e-01 0.695 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 2.017985e-01 0.695 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 2.017985e-01 0.695 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 1.812025e-01 0.742 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.812025e-01 0.742 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 2.302478e-01 0.638 0 0
Activation of RAC1 R-HSA-428540 2.302478e-01 0.638 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 2.302478e-01 0.638 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 3.015893e-01 0.521 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.015893e-01 0.521 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.015893e-01 0.521 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 3.015893e-01 0.521 0 0
SOS-mediated signalling R-HSA-112412 3.015893e-01 0.521 0 0
Recycling of eIF2:GDP R-HSA-72731 3.015893e-01 0.521 0 0
Disinhibition of SNARE formation R-HSA-114516 3.015893e-01 0.521 0 0
FasL/ CD95L signaling R-HSA-75157 4.235776e-01 0.373 0 0
MET interacts with TNS proteins R-HSA-8875513 4.235776e-01 0.373 0 0
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336 4.235776e-01 0.373 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 4.235776e-01 0.373 0 0
Axonal growth stimulation R-HSA-209563 4.235776e-01 0.373 0 0
Defective ABCC2 causes DJS R-HSA-5679001 4.235776e-01 0.373 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 4.235776e-01 0.373 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 4.235776e-01 0.373 0 0
Defective SLC7A7 causes lysinuric protein intolerance (LPI) R-HSA-5660862 4.235776e-01 0.373 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 2.593686e-01 0.586 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.593686e-01 0.586 0 0
Scavenging by Class F Receptors R-HSA-3000484 2.593686e-01 0.586 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.803230e-01 0.744 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 1.803230e-01 0.744 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 1.803230e-01 0.744 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 3.416681e-01 0.466 0 0
MET receptor recycling R-HSA-8875656 3.416681e-01 0.466 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 1.990168e-01 0.701 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 1.990168e-01 0.701 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 2.889291e-01 0.539 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 2.183343e-01 0.661 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 2.093942e-01 0.679 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.381983e-01 0.623 0 0
Deadenylation of mRNA R-HSA-429947 2.381983e-01 0.623 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 2.735399e-01 0.563 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 2.735399e-01 0.563 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.809898e-01 0.419 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 3.809898e-01 0.419 0 0
ARMS-mediated activation R-HSA-170984 3.809898e-01 0.419 0 0
Interleukin-21 signaling R-HSA-9020958 3.809898e-01 0.419 0 0
WNT mediated activation of DVL R-HSA-201688 3.809898e-01 0.419 0 0
CASP8 activity is inhibited R-HSA-5218900 3.809898e-01 0.419 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 4.837262e-01 0.315 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 4.837262e-01 0.315 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 4.837262e-01 0.315 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 4.837262e-01 0.315 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 4.837262e-01 0.315 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 2.585304e-01 0.587 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 2.978363e-01 0.526 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.978363e-01 0.526 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 2.978363e-01 0.526 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 2.978363e-01 0.526 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 2.978363e-01 0.526 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 2.978363e-01 0.526 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 3.485337e-01 0.458 0 0
Processive synthesis on the lagging strand R-HSA-69183 3.485337e-01 0.458 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 3.485337e-01 0.458 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 3.485337e-01 0.458 0 0
p38MAPK events R-HSA-171007 3.485337e-01 0.458 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 3.485337e-01 0.458 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.742736e-01 0.759 0 0
Signalling to RAS R-HSA-167044 3.223753e-01 0.492 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.192764e-01 0.377 0 0
2-LTR circle formation R-HSA-164843 4.192764e-01 0.377 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.976194e-01 0.704 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 3.002856e-01 0.522 0 0
Interaction between L1 and Ankyrins R-HSA-445095 3.002856e-01 0.522 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 3.002856e-01 0.522 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 2.338829e-01 0.631 0 0
Nucleosome assembly R-HSA-774815 2.338829e-01 0.631 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 2.810833e-01 0.551 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.810833e-01 0.551 0 0
Differentiation of T cells R-HSA-9945266 3.782092e-01 0.422 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 3.782092e-01 0.422 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 3.782092e-01 0.422 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 2.640669e-01 0.578 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 3.215549e-01 0.493 0 0
Translation initiation complex formation R-HSA-72649 2.487776e-01 0.604 0 0
MAP2K and MAPK activation R-HSA-5674135 2.978942e-01 0.526 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 3.188134e-01 0.496 0 0
PERK regulates gene expression R-HSA-381042 3.188134e-01 0.496 0 0
Signaling by Erythropoietin R-HSA-9006335 3.429860e-01 0.465 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 3.429860e-01 0.465 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.563159e-01 0.341 1 1
Degradation of CDH1 R-HSA-9766229 2.951227e-01 0.530 0 0
Dual incision in TC-NER R-HSA-6782135 3.066529e-01 0.513 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 4.365326e-01 0.360 0 0
EGFR downregulation R-HSA-182971 3.860508e-01 0.413 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 3.366869e-01 0.473 0 0
Diseases of mitotic cell cycle R-HSA-9675126 4.075514e-01 0.390 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.959208e-01 0.402 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 4.649280e-01 0.333 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 4.649280e-01 0.333 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 3.854847e-01 0.414 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 3.854847e-01 0.414 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 4.450371e-01 0.352 0 0
HIV Transcription Elongation R-HSA-167169 4.152493e-01 0.382 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 4.152493e-01 0.382 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 4.032083e-01 0.394 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.689303e-01 0.329 0 0
Regulation of CDH1 Function R-HSA-9764561 4.252761e-01 0.371 0 0
Cap-dependent Translation Initiation R-HSA-72737 4.637405e-01 0.334 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.792520e-01 0.554 0 0
Eukaryotic Translation Initiation R-HSA-72613 4.637405e-01 0.334 0 0
Regulation of endogenous retroelements R-HSA-9842860 3.663783e-01 0.436 0 0
G-protein beta:gamma signalling R-HSA-397795 4.289483e-01 0.368 0 0
Signaling by MET R-HSA-6806834 1.798547e-01 0.745 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 2.465955e-01 0.608 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 2.183343e-01 0.661 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 3.184205e-01 0.497 0 0
Activated point mutants of FGFR2 R-HSA-2033519 4.649280e-01 0.333 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 4.346755e-01 0.362 0 0
Chromosome Maintenance R-HSA-73886 3.232225e-01 0.490 0 0
G0 and Early G1 R-HSA-1538133 2.444660e-01 0.612 0 0
Generation of second messenger molecules R-HSA-202433 4.152493e-01 0.382 0 0
DNA Damage Bypass R-HSA-73893 4.385675e-01 0.358 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 3.879429e-01 0.411 0 0
Fanconi Anemia Pathway R-HSA-6783310 3.677790e-01 0.434 0 0
Receptor Mediated Mitophagy R-HSA-8934903 4.192764e-01 0.377 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 3.002856e-01 0.522 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 3.645073e-01 0.438 0 0
Mitotic Spindle Checkpoint R-HSA-69618 2.484485e-01 0.605 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 4.208232e-01 0.376 0 0
Signaling by FGFR2 R-HSA-5654738 2.686784e-01 0.571 0 0
Formation of the posterior neural plate R-HSA-9832991 2.017985e-01 0.695 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.809898e-01 0.419 0 0
Integrin signaling R-HSA-354192 2.626084e-01 0.581 0 0
DAP12 signaling R-HSA-2424491 3.645073e-01 0.438 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.803814e-01 0.744 0 0
Signaling by FGFR1 R-HSA-5654736 4.088418e-01 0.388 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.206816e-01 0.656 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 1.990168e-01 0.701 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 2.183343e-01 0.661 0 0
FGFR2 ligand binding and activation R-HSA-190241 3.223753e-01 0.492 0 0
PI3K/AKT activation R-HSA-198203 4.192764e-01 0.377 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 3.782092e-01 0.422 0 0
Attenuation phase R-HSA-3371568 4.152493e-01 0.382 0 0
Clathrin-mediated endocytosis R-HSA-8856828 4.130016e-01 0.384 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 2.792520e-01 0.554 0 0
Chaperone Mediated Autophagy R-HSA-9613829 4.649280e-01 0.333 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 3.879429e-01 0.411 0 0
TCF dependent signaling in response to WNT R-HSA-201681 3.828413e-01 0.417 0 0
Adipogenesis R-HSA-9843745 4.534032e-01 0.344 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 1.708638e-01 0.767 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 2.593686e-01 0.586 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 4.075873e-01 0.390 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 4.712066e-01 0.327 0 0
Interleukin-35 Signalling R-HSA-8984722 2.593686e-01 0.586 0 0
Interleukin-9 signaling R-HSA-8985947 3.416681e-01 0.466 0 0
Interleukin-6 family signaling R-HSA-6783589 2.381983e-01 0.623 0 0
Processing of DNA double-strand break ends R-HSA-5693607 3.924811e-01 0.406 0 0
Regulation by c-FLIP R-HSA-3371378 3.416681e-01 0.466 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 4.837262e-01 0.315 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 3.002856e-01 0.522 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 3.002856e-01 0.522 0 0
DARPP-32 events R-HSA-180024 3.429860e-01 0.465 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 4.075873e-01 0.390 0 0
TCR signaling R-HSA-202403 1.969452e-01 0.706 1 0
PKA activation R-HSA-163615 4.649280e-01 0.333 0 0
Signaling by FGFR R-HSA-190236 3.189601e-01 0.496 0 0
Signaling by WNT R-HSA-195721 2.194476e-01 0.659 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.750662e-01 0.757 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 3.184774e-01 0.497 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 4.044462e-01 0.393 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 2.593686e-01 0.586 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 2.593686e-01 0.586 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.803230e-01 0.744 0 0
Protein folding R-HSA-391251 4.490810e-01 0.348 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 3.865190e-01 0.413 1 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 4.441185e-01 0.353 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 4.032083e-01 0.394 1 1
Interleukin-27 signaling R-HSA-9020956 1.742694e-01 0.759 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 4.579990e-01 0.339 0 0
DNA Double Strand Break Response R-HSA-5693606 2.105611e-01 0.677 0 0
Meiosis R-HSA-1500620 2.317512e-01 0.635 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 4.219868e-01 0.375 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 1.808630e-01 0.743 0 0
Pyrophosphate hydrolysis R-HSA-71737 1.808630e-01 0.743 0 0
Disorders of Developmental Biology R-HSA-9675151 2.033080e-01 0.692 0 0
Dimerization of procaspase-8 R-HSA-69416 3.416681e-01 0.466 0 0
Syndecan interactions R-HSA-3000170 2.183343e-01 0.661 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.585304e-01 0.587 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 2.156226e-01 0.666 0 0
Metalloprotease DUBs R-HSA-5689901 2.792520e-01 0.554 0 0
Ca2+ pathway R-HSA-4086398 1.891268e-01 0.723 0 0
FGFR2b ligand binding and activation R-HSA-190377 4.563159e-01 0.341 0 0
Nuclear RNA decay R-HSA-9930044 4.289483e-01 0.368 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 4.289483e-01 0.368 0 0
Platelet activation, signaling and aggregation R-HSA-76002 4.807452e-01 0.318 0 0
Homology Directed Repair R-HSA-5693538 2.127823e-01 0.672 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 3.767972e-01 0.424 0 0
Apoptotic factor-mediated response R-HSA-111471 2.496040e-01 0.603 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 4.152493e-01 0.382 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 4.152493e-01 0.382 0 0
RNA Polymerase I Transcription R-HSA-73864 4.749906e-01 0.323 0 0
Attachment and Entry R-HSA-9694614 3.470452e-01 0.460 0 0
Signaling by Nuclear Receptors R-HSA-9006931 2.018520e-01 0.695 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.093942e-01 0.679 0 0
p75NTR regulates axonogenesis R-HSA-193697 3.809898e-01 0.419 0 0
PLC beta mediated events R-HSA-112043 2.349658e-01 0.629 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 4.450371e-01 0.352 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 3.996932e-01 0.398 1 1
RAF/MAP kinase cascade R-HSA-5673001 3.903723e-01 0.409 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 4.501843e-01 0.347 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 2.302478e-01 0.638 0 0
Pervasive developmental disorders R-HSA-9005895 2.593686e-01 0.586 0 0
Disorders of Nervous System Development R-HSA-9697154 2.593686e-01 0.586 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 2.593686e-01 0.586 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 3.416681e-01 0.466 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.978363e-01 0.526 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 2.626084e-01 0.581 0 0
HDACs deacetylate histones R-HSA-3214815 2.629091e-01 0.580 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 4.075873e-01 0.390 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 4.563159e-01 0.341 0 0
HATs acetylate histones R-HSA-3214847 3.306830e-01 0.481 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 4.689303e-01 0.329 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 2.810833e-01 0.551 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.429860e-01 0.465 0 0
Intraflagellar transport R-HSA-5620924 2.794324e-01 0.554 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 3.717406e-01 0.430 0 0
Chaperonin-mediated protein folding R-HSA-390466 3.700967e-01 0.432 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 4.689303e-01 0.329 0 0
Interleukin-7 signaling R-HSA-1266695 2.585304e-01 0.587 0 0
Ub-specific processing proteases R-HSA-5689880 2.268360e-01 0.644 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.978363e-01 0.526 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 3.485337e-01 0.458 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 3.485337e-01 0.458 0 0
HSF1 activation R-HSA-3371511 3.379617e-01 0.471 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 3.734421e-01 0.428 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 3.702347e-01 0.432 1 0
MAP kinase activation R-HSA-450294 4.903554e-01 0.309 1 0
GPVI-mediated activation cascade R-HSA-114604 2.002440e-01 0.698 0 0
Gastrulation R-HSA-9758941 2.279644e-01 0.642 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.809898e-01 0.419 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.479647e-01 0.606 0 0
MyD88-independent TLR4 cascade R-HSA-166166 3.702347e-01 0.432 1 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 2.639749e-01 0.578 0 0
MAPK family signaling cascades R-HSA-5683057 1.665023e-01 0.779 0 0
Organelle biogenesis and maintenance R-HSA-1852241 2.474609e-01 0.606 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 4.147531e-01 0.382 1 0
Interferon Signaling R-HSA-913531 2.671698e-01 0.573 1 0
Opioid Signalling R-HSA-111885 3.904940e-01 0.408 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 3.215549e-01 0.493 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 4.450371e-01 0.352 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.121598e-01 0.673 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.977583e-01 0.704 0 0
SDK interactions R-HSA-373756 1.977583e-01 0.704 0 0
Manipulation of host energy metabolism R-HSA-9636667 2.814559e-01 0.551 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.206816e-01 0.656 0 0
mRNA Editing: A to I Conversion R-HSA-75064 3.564258e-01 0.448 0 0
C6 deamination of adenosine R-HSA-75102 3.564258e-01 0.448 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 3.564258e-01 0.448 0 0
Regulation of cortical dendrite branching R-HSA-8985801 3.564258e-01 0.448 0 0
Neurophilin interactions with VEGF and VEGFR R-HSA-194306 3.564258e-01 0.448 0 0
Netrin mediated repulsion signals R-HSA-418886 3.015893e-01 0.521 0 0
STAT6-mediated induction of chemokines R-HSA-3249367 4.235776e-01 0.373 0 0
MET activates STAT3 R-HSA-8875791 4.235776e-01 0.373 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 4.235776e-01 0.373 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 3.416681e-01 0.466 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 3.416681e-01 0.466 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.496040e-01 0.603 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 2.496040e-01 0.603 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.183343e-01 0.661 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 2.381983e-01 0.623 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 3.187155e-01 0.497 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 4.837262e-01 0.315 0 0
GABA synthesis R-HSA-888568 4.837262e-01 0.315 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 4.837262e-01 0.315 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.156226e-01 0.666 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 2.792520e-01 0.554 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 3.223753e-01 0.492 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 2.640669e-01 0.578 1 0
Diseases of Immune System R-HSA-5260271 2.640669e-01 0.578 1 0
Gene Silencing by RNA R-HSA-211000 1.717033e-01 0.765 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.849879e-01 0.733 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 4.365326e-01 0.360 1 1
Nuclear signaling by ERBB4 R-HSA-1251985 4.152493e-01 0.382 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.170292e-01 0.380 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 4.712066e-01 0.327 0 0
Developmental Biology R-HSA-1266738 4.191673e-01 0.378 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.808541e-01 0.552 0 0
G-protein mediated events R-HSA-112040 3.162048e-01 0.500 0 0
Adaptive Immune System R-HSA-1280218 3.143877e-01 0.503 1 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 2.718330e-01 0.566 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.912520e-01 0.718 0 0
Co-stimulation by CD28 R-HSA-389356 4.209141e-01 0.376 0 0
Signaling by Insulin receptor R-HSA-74752 2.405615e-01 0.619 0 0
HIV Infection R-HSA-162906 4.653228e-01 0.332 0 0
Signaling by FGFR4 in disease R-HSA-5655291 3.187155e-01 0.497 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 4.208232e-01 0.376 0 0
Cell Cycle Checkpoints R-HSA-69620 3.566713e-01 0.448 0 0
Spry regulation of FGF signaling R-HSA-1295596 3.485337e-01 0.458 0 0
Generic Transcription Pathway R-HSA-212436 2.797231e-01 0.553 0 0
NGF-stimulated transcription R-HSA-9031628 4.209141e-01 0.376 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 2.017985e-01 0.695 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.093942e-01 0.679 0 0
NRIF signals cell death from the nucleus R-HSA-205043 3.187155e-01 0.497 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.809898e-01 0.419 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.772822e-01 0.557 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.862409e-01 0.730 0 0
Rab regulation of trafficking R-HSA-9007101 2.041396e-01 0.690 0 0
MHC class II antigen presentation R-HSA-2132295 2.583449e-01 0.588 0 0
FLT3 Signaling R-HSA-9607240 2.808541e-01 0.552 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 2.267101e-01 0.645 0 0
Other interleukin signaling R-HSA-449836 2.735399e-01 0.563 0 0
HDMs demethylate histones R-HSA-3214842 2.585304e-01 0.587 0 0
Netrin-1 signaling R-HSA-373752 2.193092e-01 0.659 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 3.645073e-01 0.438 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.734421e-01 0.428 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 2.206816e-01 0.656 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 3.717406e-01 0.430 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 3.671802e-01 0.435 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 4.416707e-01 0.355 0 0
Potential therapeutics for SARS R-HSA-9679191 2.360591e-01 0.627 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.501285e-01 0.456 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 2.314116e-01 0.636 0 0
Interleukin-12 family signaling R-HSA-447115 2.654704e-01 0.576 0 0
Regulation of KIT signaling R-HSA-1433559 3.187155e-01 0.497 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 3.825360e-01 0.417 0 0
Cardiogenesis R-HSA-9733709 4.289483e-01 0.368 0 0
Interleukin-1 family signaling R-HSA-446652 3.289021e-01 0.483 1 0
Activation of BH3-only proteins R-HSA-114452 3.645073e-01 0.438 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 2.261513e-01 0.646 0 0
S Phase R-HSA-69242 2.918444e-01 0.535 0 0
SARS-CoV-2-host interactions R-HSA-9705683 3.279303e-01 0.484 1 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.663695e-01 0.779 0 0
Signaling by PTK6 R-HSA-8848021 1.663695e-01 0.779 0 0
Breakdown of the nuclear lamina R-HSA-352238 2.814559e-01 0.551 0 0
Inhibition of membrane repair R-HSA-9635644 2.814559e-01 0.551 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 2.206816e-01 0.656 0 0
TGFBR3 PTM regulation R-HSA-9839383 3.416681e-01 0.466 0 0
TNFR1-mediated ceramide production R-HSA-5626978 4.837262e-01 0.315 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 3.223753e-01 0.492 0 0
Regulation of the apoptosome activity R-HSA-9627069 4.192764e-01 0.377 0 0
Josephin domain DUBs R-HSA-5689877 4.192764e-01 0.377 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 4.563159e-01 0.341 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 2.918719e-01 0.535 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 4.365326e-01 0.360 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 4.208232e-01 0.376 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 4.075514e-01 0.390 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 4.289483e-01 0.368 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 4.605739e-01 0.337 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.823850e-01 0.739 0 0
Signaling by NOTCH3 R-HSA-9012852 3.923956e-01 0.406 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 2.889291e-01 0.539 0 0
Formation of apoptosome R-HSA-111458 4.192764e-01 0.377 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 3.645073e-01 0.438 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 4.365326e-01 0.360 0 0
Neurofascin interactions R-HSA-447043 2.611105e-01 0.583 0 0
PECAM1 interactions R-HSA-210990 2.017985e-01 0.695 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 1.990168e-01 0.701 0 0
Tie2 Signaling R-HSA-210993 2.496040e-01 0.603 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 3.187155e-01 0.497 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 3.809898e-01 0.419 0 0
Suppression of apoptosis R-HSA-9635465 4.563159e-01 0.341 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 4.594380e-01 0.338 0 0
The NLRP3 inflammasome R-HSA-844456 2.735399e-01 0.563 0 0
Early Phase of HIV Life Cycle R-HSA-162594 3.223753e-01 0.492 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 2.206816e-01 0.656 0 0
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells R-HSA-210746 2.611105e-01 0.583 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 2.593686e-01 0.586 0 0
Regulation of gene expression in beta cells R-HSA-210745 1.925710e-01 0.715 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 3.809898e-01 0.419 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 4.837262e-01 0.315 0 0
Transmission across Electrical Synapses R-HSA-112307 4.837262e-01 0.315 0 0
Electric Transmission Across Gap Junctions R-HSA-112303 4.837262e-01 0.315 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 4.192764e-01 0.377 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 3.782092e-01 0.422 0 0
Bicarbonate transporters R-HSA-425381 4.563159e-01 0.341 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.066018e-01 0.685 0 0
Signaling by ALK R-HSA-201556 2.475727e-01 0.606 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 3.223753e-01 0.492 0 0
Mismatch Repair R-HSA-5358508 4.649280e-01 0.333 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 3.432757e-01 0.464 0 0
Signaling by Leptin R-HSA-2586552 4.192764e-01 0.377 0 0
IRE1alpha activates chaperones R-HSA-381070 3.249450e-01 0.488 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 3.015893e-01 0.521 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 3.015893e-01 0.521 0 0
Expression and Processing of Neurotrophins R-HSA-9036866 4.235776e-01 0.373 0 0
NGF processing R-HSA-167060 4.235776e-01 0.373 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 3.187155e-01 0.497 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.809898e-01 0.419 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.809898e-01 0.419 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 2.213364e-01 0.655 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 1.911391e-01 0.719 0 0
Regulation of beta-cell development R-HSA-186712 2.097748e-01 0.678 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 3.485337e-01 0.458 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 3.432757e-01 0.464 0 0
Interleukin-12 signaling R-HSA-9020591 3.242734e-01 0.489 0 0
Specification of primordial germ cells R-HSA-9827857 4.365326e-01 0.360 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 3.066529e-01 0.513 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 2.889291e-01 0.539 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 2.883415e-01 0.540 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 4.365326e-01 0.360 0 0
XBP1(S) activates chaperone genes R-HSA-381038 3.570505e-01 0.447 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 3.187155e-01 0.497 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.223753e-01 0.492 0 0
Synthesis and processing of ENV and VPU R-HSA-171286 3.564258e-01 0.448 0 0
Maturation of hRSV A proteins R-HSA-9828806 3.002856e-01 0.522 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 2.475727e-01 0.606 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 1.808630e-01 0.743 0 0
Signaling by FGFR4 R-HSA-5654743 4.914343e-01 0.309 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 4.919517e-01 0.308 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.919517e-01 0.308 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.919517e-01 0.308 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.919517e-01 0.308 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.919517e-01 0.308 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.919517e-01 0.308 0 0
Integration of provirus R-HSA-162592 4.919517e-01 0.308 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 4.919665e-01 0.308 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 4.924356e-01 0.308 0 0
Germ layer formation at gastrulation R-HSA-9754189 4.926737e-01 0.307 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 4.926737e-01 0.307 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 4.926737e-01 0.307 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 4.926737e-01 0.307 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 4.926737e-01 0.307 0 0
G2/M Checkpoints R-HSA-69481 4.978247e-01 0.303 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 4.986158e-01 0.302 1 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 4.986158e-01 0.302 1 0
SARS-CoV-2 Infection R-HSA-9694516 4.994727e-01 0.301 1 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 5.003636e-01 0.301 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.035710e-01 0.298 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 5.048701e-01 0.297 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.063360e-01 0.296 0 0
RUNX2 regulates bone development R-HSA-8941326 5.124194e-01 0.290 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 5.154935e-01 0.288 0 0
Inflammasomes R-HSA-622312 5.154935e-01 0.288 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 5.177018e-01 0.286 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 5.196862e-01 0.284 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 5.196862e-01 0.284 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 5.197734e-01 0.284 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 5.221554e-01 0.282 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 5.235579e-01 0.281 1 0
Signaling by Interleukins R-HSA-449147 5.248079e-01 0.280 1 0
MET activates RAS signaling R-HSA-8851805 5.260737e-01 0.279 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 5.260737e-01 0.279 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 5.260737e-01 0.279 0 0
Interleukin-15 signaling R-HSA-8983432 5.260737e-01 0.279 0 0
p75NTR recruits signalling complexes R-HSA-209543 5.260737e-01 0.279 0 0
OAS antiviral response R-HSA-8983711 5.260737e-01 0.279 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 5.283188e-01 0.277 0 0
Signaling by FGFR3 R-HSA-5654741 5.283188e-01 0.277 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 5.325253e-01 0.274 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 5.329853e-01 0.273 1 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 5.329853e-01 0.273 1 0
Cytokine Signaling in Immune system R-HSA-1280215 5.371490e-01 0.270 1 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 5.376016e-01 0.270 0 0
NrCAM interactions R-HSA-447038 5.376016e-01 0.270 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 5.376016e-01 0.270 0 0
IRS activation R-HSA-74713 5.376016e-01 0.270 0 0
FGFR1c and Klotho ligand binding and activation R-HSA-190374 5.376016e-01 0.270 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 5.376016e-01 0.270 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 5.376016e-01 0.270 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 5.376016e-01 0.270 0 0
Activation of AKT2 R-HSA-165158 5.376016e-01 0.270 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 5.376016e-01 0.270 0 0
Reelin signalling pathway R-HSA-8866376 5.376016e-01 0.270 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 5.376016e-01 0.270 0 0
Muscarinic acetylcholine receptors R-HSA-390648 5.376016e-01 0.270 0 0
Inositol transporters R-HSA-429593 5.376016e-01 0.270 0 0
Co-inhibition by BTLA R-HSA-9927353 5.376016e-01 0.270 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 5.376016e-01 0.270 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.377929e-01 0.269 1 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 5.380520e-01 0.269 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 5.380520e-01 0.269 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 5.380520e-01 0.269 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 5.381391e-01 0.269 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 5.397171e-01 0.268 1 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 5.397171e-01 0.268 1 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 5.397171e-01 0.268 1 0
Reproduction R-HSA-1474165 5.420751e-01 0.266 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 5.424668e-01 0.266 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 5.458972e-01 0.263 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 5.458972e-01 0.263 0 0
Lagging Strand Synthesis R-HSA-69186 5.458972e-01 0.263 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 5.458972e-01 0.263 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 5.467037e-01 0.262 1 0
Signaling by ERBB4 R-HSA-1236394 5.491120e-01 0.260 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 5.522428e-01 0.258 0 0
MET promotes cell motility R-HSA-8875878 5.522482e-01 0.258 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 5.522482e-01 0.258 0 0
Cellular response to hypoxia R-HSA-1234174 5.532295e-01 0.257 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 5.581121e-01 0.253 0 0
FGFR2c ligand binding and activation R-HSA-190375 5.586096e-01 0.253 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 5.586096e-01 0.253 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 5.586096e-01 0.253 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 5.586096e-01 0.253 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 5.586096e-01 0.253 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 5.586096e-01 0.253 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 5.586448e-01 0.253 1 0
Downstream signaling of activated FGFR4 R-HSA-5654716 5.600662e-01 0.252 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 5.613465e-01 0.251 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 5.613465e-01 0.251 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 5.646234e-01 0.248 1 0
Glycolysis R-HSA-70171 5.647369e-01 0.248 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 5.712521e-01 0.243 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 5.712521e-01 0.243 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 5.712521e-01 0.243 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 5.712521e-01 0.243 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 5.715005e-01 0.243 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.728136e-01 0.242 0 0
Transmission across Chemical Synapses R-HSA-112315 5.739031e-01 0.241 0 0
Interleukin-1 signaling R-HSA-9020702 5.770461e-01 0.239 1 1
RNA Polymerase I Promoter Clearance R-HSA-73854 5.777209e-01 0.238 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 5.814980e-01 0.235 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 5.858576e-01 0.232 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 5.858576e-01 0.232 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 5.858576e-01 0.232 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 5.858576e-01 0.232 0 0
Phosphorylation of Emi1 R-HSA-176417 5.858576e-01 0.232 0 0
Loss-of-function mutations in DBT cause MSUD2 R-HSA-9865113 5.858576e-01 0.232 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 5.858576e-01 0.232 0 0
Loss-of-function mutations in DLD cause MSUD3/DLDD R-HSA-9907570 5.858576e-01 0.232 0 0
PKB-mediated events R-HSA-109703 5.858576e-01 0.232 0 0
PDE3B signalling R-HSA-165160 5.858576e-01 0.232 0 0
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399 5.858576e-01 0.232 0 0
Relaxin receptors R-HSA-444821 5.858576e-01 0.232 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 5.858576e-01 0.232 0 0
VEGF ligand-receptor interactions R-HSA-194313 5.858576e-01 0.232 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 5.858576e-01 0.232 1 1
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 5.861721e-01 0.232 0 0
Removal of the Flap Intermediate R-HSA-69166 5.895190e-01 0.230 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 5.895190e-01 0.230 0 0
Physiological factors R-HSA-5578768 5.895190e-01 0.230 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 5.904211e-01 0.229 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 5.904211e-01 0.229 0 0
SARS-CoV Infections R-HSA-9679506 5.914653e-01 0.228 1 0
FRS-mediated FGFR4 signaling R-HSA-5654712 5.957089e-01 0.225 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 5.957089e-01 0.225 0 0
Transcription of the HIV genome R-HSA-167172 5.981623e-01 0.223 0 0
Integrin cell surface interactions R-HSA-216083 6.054882e-01 0.218 0 0
Vesicle-mediated transport R-HSA-5653656 6.137519e-01 0.212 0 0
G beta:gamma signalling through BTK R-HSA-8964315 6.187870e-01 0.208 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 6.187870e-01 0.208 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 6.187870e-01 0.208 0 0
Biotin transport and metabolism R-HSA-196780 6.187870e-01 0.208 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 6.187870e-01 0.208 0 0
Sensory processing of sound R-HSA-9659379 6.190259e-01 0.208 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 6.192369e-01 0.208 0 0
Interleukin-20 family signaling R-HSA-8854691 6.192369e-01 0.208 0 0
Formation of the ureteric bud R-HSA-9830674 6.192369e-01 0.208 0 0
Growth hormone receptor signaling R-HSA-982772 6.192369e-01 0.208 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 6.193167e-01 0.208 0 0
RSV-host interactions R-HSA-9833110 6.247331e-01 0.204 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 6.252455e-01 0.204 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 6.267302e-01 0.203 0 0
Interleukin-17 signaling R-HSA-448424 6.268228e-01 0.203 1 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 6.290802e-01 0.201 0 0
STAT5 Activation R-HSA-9645135 6.290802e-01 0.201 0 0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD R-HSA-9865125 6.290802e-01 0.201 0 0
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) R-HSA-5619070 6.290802e-01 0.201 0 0
Branched-chain ketoacid dehydrogenase kinase deficiency R-HSA-9912481 6.290802e-01 0.201 0 0
H139Hfs13* PPM1K causes a mild variant of MSUD R-HSA-9912529 6.290802e-01 0.201 0 0
MET Receptor Activation R-HSA-6806942 6.290802e-01 0.201 0 0
Signaling by LTK in cancer R-HSA-9842640 6.290802e-01 0.201 0 0
HDL clearance R-HSA-8964011 6.290802e-01 0.201 0 0
Nef and signal transduction R-HSA-164944 6.290802e-01 0.201 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 6.290802e-01 0.201 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 6.307783e-01 0.200 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 6.418154e-01 0.193 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 6.418154e-01 0.193 0 0
Regulation of BACH1 activity R-HSA-9708530 6.464195e-01 0.189 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 6.464195e-01 0.189 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 6.464195e-01 0.189 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 6.464195e-01 0.189 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 6.464195e-01 0.189 0 0
Attachment and Entry R-HSA-9678110 6.464195e-01 0.189 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 6.464195e-01 0.189 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 6.464195e-01 0.189 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 6.464195e-01 0.189 0 0
Negative regulation of FLT3 R-HSA-9706369 6.464195e-01 0.189 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 6.464195e-01 0.189 0 0
Virus Assembly and Release R-HSA-168268 6.464195e-01 0.189 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 6.464359e-01 0.189 0 0
SARS-CoV-1 Infection R-HSA-9678108 6.470479e-01 0.189 0 0
NCAM signaling for neurite out-growth R-HSA-375165 6.506377e-01 0.187 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 6.506377e-01 0.187 0 0
Host Interactions of HIV factors R-HSA-162909 6.567933e-01 0.183 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 6.608546e-01 0.180 0 0
Dual Incision in GG-NER R-HSA-5696400 6.608546e-01 0.180 0 0
Signaling by NOTCH2 R-HSA-1980145 6.608546e-01 0.180 0 0
Signal amplification R-HSA-392518 6.608546e-01 0.180 0 0
Mitophagy R-HSA-5205647 6.608546e-01 0.180 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 6.608546e-01 0.180 0 0
NOD1/2 Signaling Pathway R-HSA-168638 6.608546e-01 0.180 1 1
NPAS4 regulates expression of target genes R-HSA-9768919 6.608546e-01 0.180 0 0
Response of Mtb to phagocytosis R-HSA-9637690 6.610262e-01 0.180 0 0
Circadian clock R-HSA-9909396 6.611955e-01 0.180 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 6.625789e-01 0.179 0 0
Acyl chain remodelling of PS R-HSA-1482801 6.634329e-01 0.178 0 0
HCMV Early Events R-HSA-9609690 6.645677e-01 0.177 0 0
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782 6.677941e-01 0.175 0 0
CHL1 interactions R-HSA-447041 6.677941e-01 0.175 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 6.677941e-01 0.175 0 0
PTK6 Expression R-HSA-8849473 6.677941e-01 0.175 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 6.677941e-01 0.175 0 0
Regulation of PTEN localization R-HSA-8948747 6.677941e-01 0.175 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 6.677941e-01 0.175 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 6.677941e-01 0.175 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 6.677941e-01 0.175 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 6.695800e-01 0.174 1 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 6.709944e-01 0.173 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 6.724390e-01 0.172 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 6.724390e-01 0.172 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 6.724390e-01 0.172 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 6.724390e-01 0.172 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 6.724390e-01 0.172 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 6.724390e-01 0.172 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 6.724390e-01 0.172 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 6.724390e-01 0.172 0 0
Response to metal ions R-HSA-5660526 6.724390e-01 0.172 0 0
G1/S Transition R-HSA-69206 6.770098e-01 0.169 0 0
DAP12 interactions R-HSA-2172127 6.773873e-01 0.169 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 6.803021e-01 0.167 1 0
Influenza Infection R-HSA-168255 6.813498e-01 0.167 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 6.828722e-01 0.166 0 0
Mitochondrial biogenesis R-HSA-1592230 6.835857e-01 0.165 0 0
MET activates PTK2 signaling R-HSA-8874081 6.840855e-01 0.165 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 6.932968e-01 0.159 0 0
Glycosphingolipid transport R-HSA-9845576 6.964814e-01 0.157 0 0
G1/S-Specific Transcription R-HSA-69205 6.964814e-01 0.157 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 6.968811e-01 0.157 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 6.968811e-01 0.157 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 6.968811e-01 0.157 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 6.968811e-01 0.157 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 6.968811e-01 0.157 0 0
PI Metabolism R-HSA-1483255 6.988305e-01 0.156 0 0
RSK activation R-HSA-444257 7.024693e-01 0.153 0 0
phospho-PLA2 pathway R-HSA-111995 7.024693e-01 0.153 0 0
FGFR1b ligand binding and activation R-HSA-190370 7.024693e-01 0.153 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 7.024693e-01 0.153 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 7.024693e-01 0.153 0 0
Formation of annular gap junctions R-HSA-196025 7.024693e-01 0.153 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 7.024693e-01 0.153 0 0
Activation of RAS in B cells R-HSA-1169092 7.024693e-01 0.153 0 0
Co-stimulation by ICOS R-HSA-9927354 7.024693e-01 0.153 0 0
Adrenoceptors R-HSA-390696 7.024693e-01 0.153 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 7.024693e-01 0.153 0 0
Alpha-defensins R-HSA-1462054 7.024693e-01 0.153 0 0
Sodium/Proton exchangers R-HSA-425986 7.024693e-01 0.153 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 7.024693e-01 0.153 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 7.037766e-01 0.153 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.037766e-01 0.153 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 7.084983e-01 0.150 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 7.084983e-01 0.150 0 0
Diseases of DNA repair R-HSA-9675135 7.084983e-01 0.150 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 7.088467e-01 0.149 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 7.118158e-01 0.148 0 0
Signaling by NOTCH R-HSA-157118 7.163811e-01 0.145 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 7.178594e-01 0.144 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 7.197917e-01 0.143 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 7.197917e-01 0.143 0 0
FGFR1 ligand binding and activation R-HSA-190242 7.197917e-01 0.143 0 0
Polo-like kinase mediated events R-HSA-156711 7.197917e-01 0.143 0 0
PKA activation in glucagon signalling R-HSA-164378 7.197917e-01 0.143 0 0
Presynaptic function of Kainate receptors R-HSA-500657 7.197917e-01 0.143 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 7.197917e-01 0.143 0 0
Platelet sensitization by LDL R-HSA-432142 7.197917e-01 0.143 0 0
Nephron development R-HSA-9831926 7.197917e-01 0.143 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 7.197917e-01 0.143 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 7.211013e-01 0.142 1 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 7.225151e-01 0.141 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 7.225151e-01 0.141 0 0
Formation of the Early Elongation Complex R-HSA-113418 7.225151e-01 0.141 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 7.293429e-01 0.137 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 7.297858e-01 0.137 0 0
Activation of HOX genes during differentiation R-HSA-5619507 7.297858e-01 0.137 0 0
Regulated Necrosis R-HSA-5218859 7.306101e-01 0.136 0 0
Gap junction degradation R-HSA-190873 7.335270e-01 0.135 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 7.335270e-01 0.135 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 7.335270e-01 0.135 0 0
Lipophagy R-HSA-9613354 7.335270e-01 0.135 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 7.335270e-01 0.135 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 7.335270e-01 0.135 0 0
mRNA Editing R-HSA-75072 7.335270e-01 0.135 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 7.335270e-01 0.135 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 7.335270e-01 0.135 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 7.335270e-01 0.135 0 0
Cellular response to mitochondrial stress R-HSA-9840373 7.335270e-01 0.135 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 7.335270e-01 0.135 0 0
GPER1 signaling R-HSA-9634597 7.374412e-01 0.132 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.403153e-01 0.131 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 7.403153e-01 0.131 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 7.407055e-01 0.130 0 0
Translesion Synthesis by POLH R-HSA-110320 7.412241e-01 0.130 0 0
Specification of the neural plate border R-HSA-9834899 7.412241e-01 0.130 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 7.412241e-01 0.130 0 0
Extension of Telomeres R-HSA-180786 7.458661e-01 0.127 0 0
SARS-CoV-1-host interactions R-HSA-9692914 7.492280e-01 0.125 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 7.517276e-01 0.124 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 7.542443e-01 0.122 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 7.571956e-01 0.121 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.571956e-01 0.121 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 7.571956e-01 0.121 0 0
Post-translational protein phosphorylation R-HSA-8957275 7.592031e-01 0.120 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 7.594654e-01 0.119 0 0
Interleukin-2 family signaling R-HSA-451927 7.594654e-01 0.119 0 0
Downstream TCR signaling R-HSA-202424 7.604150e-01 0.119 1 1
VxPx cargo-targeting to cilium R-HSA-5620916 7.612372e-01 0.118 0 0
Protein hydroxylation R-HSA-9629569 7.612372e-01 0.118 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 7.612372e-01 0.118 0 0
Signaling by NODAL R-HSA-1181150 7.612372e-01 0.118 0 0
Pregnenolone biosynthesis R-HSA-196108 7.612372e-01 0.118 0 0
Binding and entry of HIV virion R-HSA-173107 7.613444e-01 0.118 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 7.613444e-01 0.118 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 7.613444e-01 0.118 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 7.613444e-01 0.118 0 0
Signal attenuation R-HSA-74749 7.613444e-01 0.118 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 7.613444e-01 0.118 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 7.613444e-01 0.118 0 0
Pexophagy R-HSA-9664873 7.613444e-01 0.118 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 7.613444e-01 0.118 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 7.613444e-01 0.118 0 0
Maturation of spike protein R-HSA-9683686 7.613444e-01 0.118 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 7.613444e-01 0.118 0 0
tRNA processing R-HSA-72306 7.628947e-01 0.118 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 7.677023e-01 0.115 0 0
FOXO-mediated transcription R-HSA-9614085 7.686911e-01 0.114 0 0
Formation of paraxial mesoderm R-HSA-9793380 7.700617e-01 0.113 0 0
Toll-like Receptor Cascades R-HSA-168898 7.723414e-01 0.112 1 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 7.735203e-01 0.112 0 0
Glucose metabolism R-HSA-70326 7.757597e-01 0.110 0 0
Hedgehog 'off' state R-HSA-5610787 7.779127e-01 0.109 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 7.798937e-01 0.108 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 7.798937e-01 0.108 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 7.798937e-01 0.108 0 0
Platelet degranulation R-HSA-114608 7.834124e-01 0.106 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 7.862594e-01 0.104 0 0
Interleukin-2 signaling R-HSA-9020558 7.862594e-01 0.104 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 7.862594e-01 0.104 0 0
vRNP Assembly R-HSA-192905 7.862594e-01 0.104 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 7.862594e-01 0.104 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 7.862594e-01 0.104 0 0
Inorganic anion exchange by SLC26 transporters R-HSA-427601 7.862594e-01 0.104 0 0
Vitamin B1 (thiamin) metabolism R-HSA-196819 7.862594e-01 0.104 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.862594e-01 0.104 0 0
Intra-Golgi traffic R-HSA-6811438 7.869200e-01 0.104 0 0
Negative regulation of MAPK pathway R-HSA-5675221 7.869200e-01 0.104 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.882876e-01 0.103 0 0
Signaling by NOTCH4 R-HSA-9013694 7.969596e-01 0.099 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 7.972586e-01 0.098 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 7.972586e-01 0.098 0 0
Smooth Muscle Contraction R-HSA-445355 8.004404e-01 0.097 0 0
Proton-coupled monocarboxylate transport R-HSA-433692 8.085746e-01 0.092 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 8.085746e-01 0.092 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 8.085746e-01 0.092 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 8.085746e-01 0.092 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 8.085746e-01 0.092 0 0
FGFR2 alternative splicing R-HSA-6803529 8.133983e-01 0.090 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 8.133983e-01 0.090 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 8.133983e-01 0.090 0 0
Striated Muscle Contraction R-HSA-390522 8.159988e-01 0.088 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 8.159988e-01 0.088 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 8.159988e-01 0.088 0 0
Effects of PIP2 hydrolysis R-HSA-114508 8.159988e-01 0.088 0 0
Cyclin D associated events in G1 R-HSA-69231 8.233372e-01 0.084 0 0
G1 Phase R-HSA-69236 8.233372e-01 0.084 0 0
RMTs methylate histone arginines R-HSA-3214858 8.233372e-01 0.084 0 0
Interleukin receptor SHC signaling R-HSA-912526 8.283792e-01 0.082 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 8.283792e-01 0.082 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 8.283792e-01 0.082 0 0
Termination of O-glycan biosynthesis R-HSA-977068 8.283792e-01 0.082 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 8.283792e-01 0.082 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 8.283792e-01 0.082 0 0
Carnitine shuttle R-HSA-200425 8.283792e-01 0.082 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 8.285612e-01 0.082 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 8.285612e-01 0.082 0 0
Maple Syrup Urine Disease R-HSA-9865114 8.285612e-01 0.082 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 8.285612e-01 0.082 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 8.285612e-01 0.082 0 0
VLDLR internalisation and degradation R-HSA-8866427 8.285612e-01 0.082 0 0
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854 8.285612e-01 0.082 0 0
GRB2 events in EGFR signaling R-HSA-179812 8.285612e-01 0.082 0 0
IRAK1 recruits IKK complex R-HSA-937039 8.285612e-01 0.082 1 1
Polymerase switching R-HSA-69091 8.285612e-01 0.082 0 0
Leading Strand Synthesis R-HSA-69109 8.285612e-01 0.082 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 8.285612e-01 0.082 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 8.285612e-01 0.082 1 1
SHC-related events triggered by IGF1R R-HSA-2428933 8.285612e-01 0.082 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 8.285612e-01 0.082 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 8.285612e-01 0.082 0 0
Signaling by LTK R-HSA-9842663 8.285612e-01 0.082 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 8.285612e-01 0.082 0 0
Calnexin/calreticulin cycle R-HSA-901042 8.286599e-01 0.082 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 8.291574e-01 0.081 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 8.319841e-01 0.080 0 0
Kidney development R-HSA-9830369 8.322694e-01 0.080 0 0
Telomere Maintenance R-HSA-157579 8.390564e-01 0.076 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 8.422673e-01 0.075 0 0
Neurodegenerative Diseases R-HSA-8863678 8.422673e-01 0.075 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.441562e-01 0.074 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.446356e-01 0.073 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.446356e-01 0.073 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 8.464621e-01 0.072 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 8.464621e-01 0.072 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 8.464621e-01 0.072 0 0
FGFR1c ligand binding and activation R-HSA-190373 8.464621e-01 0.072 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 8.464621e-01 0.072 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 8.464621e-01 0.072 0 0
CD28 dependent Vav1 pathway R-HSA-389359 8.464621e-01 0.072 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 8.464621e-01 0.072 0 0
Maturation of nucleoprotein R-HSA-9683610 8.464621e-01 0.072 0 0
Base Excision Repair R-HSA-73884 8.514653e-01 0.070 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 8.517496e-01 0.070 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.517496e-01 0.070 0 0
Triglyceride catabolism R-HSA-163560 8.517496e-01 0.070 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 8.546201e-01 0.068 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 8.551275e-01 0.068 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 8.551275e-01 0.068 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 8.551275e-01 0.068 0 0
Triglyceride metabolism R-HSA-8979227 8.595681e-01 0.066 0 0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV R-HSA-9859138 8.624948e-01 0.064 0 0
Retrograde neurotrophin signalling R-HSA-177504 8.624948e-01 0.064 0 0
CRMPs in Sema3A signaling R-HSA-399956 8.624948e-01 0.064 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 8.624948e-01 0.064 0 0
Hydrolysis of LPC R-HSA-1483115 8.624948e-01 0.064 0 0
Prolactin receptor signaling R-HSA-1170546 8.624948e-01 0.064 0 0
Glycerophospholipid catabolism R-HSA-6814848 8.624948e-01 0.064 0 0
Acyl chain remodeling of CL R-HSA-1482798 8.624948e-01 0.064 0 0
Zinc transporters R-HSA-435354 8.624948e-01 0.064 0 0
P2Y receptors R-HSA-417957 8.624948e-01 0.064 0 0
Metal ion SLC transporters R-HSA-425410 8.637268e-01 0.064 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 8.651169e-01 0.063 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 8.670229e-01 0.062 0 0
Sphingolipid catabolism R-HSA-9845614 8.670229e-01 0.062 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 8.670229e-01 0.062 0 0
TRP channels R-HSA-3295583 8.670229e-01 0.062 0 0
Suppression of phagosomal maturation R-HSA-9637687 8.670229e-01 0.062 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 8.678410e-01 0.062 0 0
Signaling by Hedgehog R-HSA-5358351 8.699520e-01 0.061 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 8.706650e-01 0.060 0 0
Elastic fibre formation R-HSA-1566948 8.720764e-01 0.059 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 8.720764e-01 0.059 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 8.724948e-01 0.059 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 8.731153e-01 0.059 0 0
Translesion synthesis by REV1 R-HSA-110312 8.768542e-01 0.057 0 0
Telomere C-strand synthesis initiation R-HSA-174430 8.768542e-01 0.057 0 0
Protein lipoylation R-HSA-9857492 8.768542e-01 0.057 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 8.768542e-01 0.057 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 8.768542e-01 0.057 1 1
SHC1 events in EGFR signaling R-HSA-180336 8.768542e-01 0.057 0 0
Other semaphorin interactions R-HSA-416700 8.768542e-01 0.057 0 0
Transport and metabolism of PAPS R-HSA-174362 8.768542e-01 0.057 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 8.768542e-01 0.057 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 8.768542e-01 0.057 0 0
Protein methylation R-HSA-8876725 8.768542e-01 0.057 0 0
DNA Damage Reversal R-HSA-73942 8.768542e-01 0.057 0 0
Cristae formation R-HSA-8949613 8.780147e-01 0.056 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 8.780147e-01 0.056 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 8.780147e-01 0.056 0 0
Triglyceride biosynthesis R-HSA-75109 8.780147e-01 0.056 0 0
Synthesis of PE R-HSA-1483213 8.780147e-01 0.056 0 0
Leishmania phagocytosis R-HSA-9664417 8.804365e-01 0.055 0 0
Parasite infection R-HSA-9664407 8.804365e-01 0.055 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 8.804365e-01 0.055 0 0
Regulation of RAS by GAPs R-HSA-5658442 8.807714e-01 0.055 0 0
RAS processing R-HSA-9648002 8.812840e-01 0.055 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 8.812840e-01 0.055 0 0
Protein-protein interactions at synapses R-HSA-6794362 8.852903e-01 0.053 0 0
Telomere Extension By Telomerase R-HSA-171319 8.881619e-01 0.052 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 8.881619e-01 0.052 0 0
Pyrimidine salvage R-HSA-73614 8.881619e-01 0.052 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.881619e-01 0.052 0 0
Meiotic recombination R-HSA-912446 8.885770e-01 0.051 0 0
Translesion synthesis by POLI R-HSA-5656121 8.897148e-01 0.051 0 0
Phosphorylation of the APC/C R-HSA-176412 8.897148e-01 0.051 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 8.897148e-01 0.051 0 0
Killing mechanisms R-HSA-9664420 8.897148e-01 0.051 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 8.897148e-01 0.051 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 8.897148e-01 0.051 1 1
Phase 4 - resting membrane potential R-HSA-5576886 8.897148e-01 0.051 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 8.897148e-01 0.051 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 8.897148e-01 0.051 0 0
Activation of SMO R-HSA-5635838 8.897148e-01 0.051 0 0
Atorvastatin ADME R-HSA-9754706 8.897148e-01 0.051 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 8.898965e-01 0.051 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 8.898965e-01 0.051 0 0
Glycogen metabolism R-HSA-8982491 8.898965e-01 0.051 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 8.904821e-01 0.050 1 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 8.911132e-01 0.050 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 8.933736e-01 0.049 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.959320e-01 0.048 0 0
Neurexins and neuroligins R-HSA-6794361 8.959320e-01 0.048 0 0
mRNA Capping R-HSA-72086 8.975210e-01 0.047 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 8.975210e-01 0.047 0 0
Platelet calcium homeostasis R-HSA-418360 8.975210e-01 0.047 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 8.979450e-01 0.047 0 0
UCH proteinases R-HSA-5689603 8.994835e-01 0.046 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.011541e-01 0.045 0 0
Translesion synthesis by POLK R-HSA-5655862 9.012330e-01 0.045 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 9.012330e-01 0.045 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 9.012330e-01 0.045 0 0
Phase 2 - plateau phase R-HSA-5576893 9.012330e-01 0.045 0 0
Glycine degradation R-HSA-6783984 9.012330e-01 0.045 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 9.012330e-01 0.045 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 9.012330e-01 0.045 0 0
Fibronectin matrix formation R-HSA-1566977 9.012330e-01 0.045 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.012330e-01 0.045 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 9.012330e-01 0.045 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.028565e-01 0.044 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 9.054596e-01 0.043 0 0
HIV Transcription Initiation R-HSA-167161 9.054596e-01 0.043 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 9.054596e-01 0.043 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.054596e-01 0.043 0 0
Synthesis of DNA R-HSA-69239 9.059839e-01 0.043 0 0
Cellular response to chemical stress R-HSA-9711123 9.062719e-01 0.043 0 0
SLC transporter disorders R-HSA-5619102 9.103260e-01 0.041 0 0
PCP/CE pathway R-HSA-4086400 9.108058e-01 0.041 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 9.115489e-01 0.040 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 9.115489e-01 0.040 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 9.115489e-01 0.040 0 0
Glycogen storage diseases R-HSA-3229121 9.115489e-01 0.040 0 0
Catecholamine biosynthesis R-HSA-209905 9.115489e-01 0.040 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.124697e-01 0.040 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 9.124697e-01 0.040 0 0
Budding and maturation of HIV virion R-HSA-162588 9.140876e-01 0.039 0 0
DNA Replication Pre-Initiation R-HSA-69002 9.152109e-01 0.038 0 0
G alpha (z) signalling events R-HSA-418597 9.154926e-01 0.038 0 0
Neurotransmitter release cycle R-HSA-112310 9.181043e-01 0.037 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 9.189265e-01 0.037 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 9.190038e-01 0.037 0 0
Synaptic adhesion-like molecules R-HSA-8849932 9.207878e-01 0.036 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 9.207878e-01 0.036 0 0
Ion homeostasis R-HSA-5578775 9.212429e-01 0.036 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 9.253488e-01 0.034 0 0
Dectin-2 family R-HSA-5621480 9.266394e-01 0.033 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 9.290622e-01 0.032 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 9.290622e-01 0.032 0 0
E2F mediated regulation of DNA replication R-HSA-113510 9.290622e-01 0.032 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.290622e-01 0.032 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 9.290622e-01 0.032 1 1
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.290622e-01 0.032 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.290622e-01 0.032 0 0
Maturation of nucleoprotein R-HSA-9694631 9.290622e-01 0.032 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 9.290622e-01 0.032 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 9.301176e-01 0.031 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 9.307531e-01 0.031 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.307531e-01 0.031 0 0
Somitogenesis R-HSA-9824272 9.307531e-01 0.031 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.307531e-01 0.031 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 9.307531e-01 0.031 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.342871e-01 0.030 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.343879e-01 0.029 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 9.346128e-01 0.029 0 0
Regulation of mitotic cell cycle R-HSA-453276 9.346128e-01 0.029 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.346128e-01 0.029 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.360201e-01 0.029 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.364433e-01 0.029 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.364433e-01 0.029 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 9.364727e-01 0.029 0 0
Glycogen synthesis R-HSA-3322077 9.364727e-01 0.029 0 0
Melanin biosynthesis R-HSA-5662702 9.364727e-01 0.029 0 0
Creatine metabolism R-HSA-71288 9.364727e-01 0.029 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.364727e-01 0.029 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 9.365805e-01 0.028 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 9.388472e-01 0.027 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.399557e-01 0.027 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.399557e-01 0.027 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 9.399557e-01 0.027 0 0
tRNA Aminoacylation R-HSA-379724 9.408851e-01 0.026 0 0
HCMV Infection R-HSA-9609646 9.419928e-01 0.026 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.428334e-01 0.026 0 0
G-protein activation R-HSA-202040 9.431094e-01 0.025 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 9.431094e-01 0.025 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 9.431094e-01 0.025 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 9.431094e-01 0.025 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 9.431094e-01 0.025 0 0
ERK/MAPK targets R-HSA-198753 9.431094e-01 0.025 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.431094e-01 0.025 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 9.435107e-01 0.025 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 9.435107e-01 0.025 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 9.435107e-01 0.025 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.451575e-01 0.024 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.457203e-01 0.024 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 9.490532e-01 0.023 0 0
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377 9.490532e-01 0.023 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.490532e-01 0.023 0 0
Assembly Of The HIV Virion R-HSA-175474 9.490532e-01 0.023 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.499283e-01 0.022 0 0
NCAM1 interactions R-HSA-419037 9.543011e-01 0.020 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 9.543763e-01 0.020 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 9.543763e-01 0.020 0 0
LDL clearance R-HSA-8964038 9.543763e-01 0.020 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 9.543763e-01 0.020 0 0
Diseases of programmed cell death R-HSA-9645723 9.552653e-01 0.020 0 0
The phototransduction cascade R-HSA-2514856 9.572189e-01 0.019 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.591435e-01 0.018 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.591435e-01 0.018 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 9.591435e-01 0.018 0 0
ABC-family proteins mediated transport R-HSA-382556 9.601629e-01 0.018 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.605787e-01 0.017 0 0
Orc1 removal from chromatin R-HSA-68949 9.605787e-01 0.017 0 0
Neuronal System R-HSA-112316 9.607515e-01 0.017 0 0
Stabilization of p53 R-HSA-69541 9.619754e-01 0.017 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.619754e-01 0.017 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.619754e-01 0.017 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.619754e-01 0.017 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.620848e-01 0.017 0 0
DNA Replication R-HSA-69306 9.633199e-01 0.016 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.634128e-01 0.016 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.634128e-01 0.016 0 0
Synthesis of dolichyl-phosphate R-HSA-446199 9.634128e-01 0.016 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.634128e-01 0.016 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 9.636894e-01 0.016 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 9.636894e-01 0.016 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.636894e-01 0.016 0 0
Hemostasis R-HSA-109582 9.641748e-01 0.016 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.648422e-01 0.016 0 0
Formation of the cornified envelope R-HSA-6809371 9.668613e-01 0.015 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 9.672362e-01 0.014 0 0
G protein gated Potassium channels R-HSA-1296059 9.672362e-01 0.014 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 9.672362e-01 0.014 0 0
Tight junction interactions R-HSA-420029 9.672362e-01 0.014 0 0
Formation of the nephric duct R-HSA-9830364 9.672362e-01 0.014 0 0
Laminin interactions R-HSA-3000157 9.672362e-01 0.014 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.678482e-01 0.014 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.678912e-01 0.014 1 1
Hh mutants are degraded by ERAD R-HSA-5362768 9.684035e-01 0.014 0 0
Maturation of spike protein R-HSA-9694548 9.684035e-01 0.014 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 9.692298e-01 0.014 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.699376e-01 0.013 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.706603e-01 0.013 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 9.706603e-01 0.013 0 0
Urea cycle R-HSA-70635 9.706603e-01 0.013 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.706603e-01 0.013 0 0
Muscle contraction R-HSA-397014 9.709258e-01 0.013 0 0
Translation of Structural Proteins R-HSA-9683701 9.712114e-01 0.013 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 9.716904e-01 0.012 0 0
Collagen formation R-HSA-1474290 9.719014e-01 0.012 0 0
COPII-mediated vesicle transport R-HSA-204005 9.720345e-01 0.012 0 0
Integration of energy metabolism R-HSA-163685 9.723898e-01 0.012 0 0
Signaling by ROBO receptors R-HSA-376176 9.725095e-01 0.012 0 0
Post-translational protein modification R-HSA-597592 9.736937e-01 0.012 0 0
Packaging Of Telomere Ends R-HSA-171306 9.737267e-01 0.012 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 9.737267e-01 0.012 0 0
Insulin processing R-HSA-264876 9.737267e-01 0.012 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.737778e-01 0.012 0 0
Depyrimidination R-HSA-73928 9.737778e-01 0.012 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.737778e-01 0.012 0 0
Synthesis of PA R-HSA-1483166 9.739638e-01 0.011 0 0
Parasitic Infection Pathways R-HSA-9824443 9.745900e-01 0.011 0 0
Leishmania infection R-HSA-9658195 9.745900e-01 0.011 0 0
Formation of a pool of free 40S subunits R-HSA-72689 9.754790e-01 0.011 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.761224e-01 0.010 0 0
Defective pyroptosis R-HSA-9710421 9.761224e-01 0.010 0 0
Insulin receptor recycling R-HSA-77387 9.764728e-01 0.010 0 0
Amine ligand-binding receptors R-HSA-375280 9.782636e-01 0.010 0 0
Late endosomal microautophagy R-HSA-9615710 9.789320e-01 0.009 0 0
DNA methylation R-HSA-5334118 9.789320e-01 0.009 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 9.789320e-01 0.009 0 0
Glucagon-type ligand receptors R-HSA-420092 9.789320e-01 0.009 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.789320e-01 0.009 0 0
Immune System R-HSA-168256 9.793696e-01 0.009 1 0
RAB geranylgeranylation R-HSA-8873719 9.797884e-01 0.009 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.802182e-01 0.009 1 1
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.802182e-01 0.009 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.802182e-01 0.009 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.802182e-01 0.009 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.802182e-01 0.009 0 0
Cardiac conduction R-HSA-5576891 9.806381e-01 0.008 0 0
rRNA processing R-HSA-72312 9.808626e-01 0.008 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.811343e-01 0.008 0 0
Aquaporin-mediated transport R-HSA-445717 9.814369e-01 0.008 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.820018e-01 0.008 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 9.828266e-01 0.008 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 9.828266e-01 0.008 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.828266e-01 0.008 0 0
ER-Phagosome pathway R-HSA-1236974 9.829185e-01 0.007 1 1
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 9.829564e-01 0.007 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 9.831065e-01 0.007 0 0
Cargo concentration in the ER R-HSA-5694530 9.831065e-01 0.007 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.831065e-01 0.007 0 0
Synthesis of PC R-HSA-1483191 9.836288e-01 0.007 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 9.843565e-01 0.007 0 0
Inwardly rectifying K+ channels R-HSA-1296065 9.848726e-01 0.007 0 0
HS-GAG degradation R-HSA-2024096 9.848726e-01 0.007 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 9.848726e-01 0.007 0 0
Cellular response to starvation R-HSA-9711097 9.854416e-01 0.006 0 0
Ion transport by P-type ATPases R-HSA-936837 9.856460e-01 0.006 0 0
Defective B3GALTL causes PpS R-HSA-5083635 9.864542e-01 0.006 0 0
Neutrophil degranulation R-HSA-6798695 9.864585e-01 0.006 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 9.864650e-01 0.006 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 9.864650e-01 0.006 0 0
Developmental Cell Lineages R-HSA-9734767 9.872438e-01 0.006 0 0
Interferon alpha/beta signaling R-HSA-909733 9.877555e-01 0.005 0 0
Miscellaneous transport and binding events R-HSA-5223345 9.878705e-01 0.005 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.878705e-01 0.005 0 0
Heme degradation R-HSA-189483 9.878705e-01 0.005 0 0
Assembly of the pre-replicative complex R-HSA-68867 9.882574e-01 0.005 0 0
Viral Infection Pathways R-HSA-9824446 9.883468e-01 0.005 1 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.888204e-01 0.005 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.888204e-01 0.005 0 0
Complex IV assembly R-HSA-9864848 9.888204e-01 0.005 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.891388e-01 0.005 0 0
eNOS activation R-HSA-203615 9.891388e-01 0.005 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.891388e-01 0.005 0 0
Hyaluronan metabolism R-HSA-2142845 9.891388e-01 0.005 0 0
Phosphate bond hydrolysis by NUDT proteins R-HSA-2393930 9.891388e-01 0.005 0 0
Neddylation R-HSA-8951664 9.894860e-01 0.005 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 9.898430e-01 0.004 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.898548e-01 0.004 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.902745e-01 0.004 0 0
Regulation of Apoptosis R-HSA-169911 9.902745e-01 0.004 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.902745e-01 0.004 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.902745e-01 0.004 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.906565e-01 0.004 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.908903e-01 0.004 1 0
Disorders of transmembrane transporters R-HSA-5619115 9.909118e-01 0.004 0 0
HS-GAG biosynthesis R-HSA-2022928 9.912916e-01 0.004 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.916216e-01 0.004 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.916216e-01 0.004 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.916377e-01 0.004 0 0
ECM proteoglycans R-HSA-3000178 9.922023e-01 0.003 0 0
Degradation of AXIN R-HSA-4641257 9.922023e-01 0.003 0 0
O-glycosylation of TSR domain-containing proteins R-HSA-5173214 9.922023e-01 0.003 0 0
Degradation of DVL R-HSA-4641258 9.922023e-01 0.003 0 0
Cleavage of the damaged purine R-HSA-110331 9.922023e-01 0.003 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.922023e-01 0.003 0 0
Collagen chain trimerization R-HSA-8948216 9.922023e-01 0.003 0 0
Paracetamol ADME R-HSA-9753281 9.923928e-01 0.003 0 0
Regulation of insulin secretion R-HSA-422356 9.925848e-01 0.003 0 0
HCMV Late Events R-HSA-9610379 9.926752e-01 0.003 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.928609e-01 0.003 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.930179e-01 0.003 0 0
Depurination R-HSA-73927 9.930179e-01 0.003 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.944021e-01 0.002 0 0
Tryptophan catabolism R-HSA-71240 9.944021e-01 0.002 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.944021e-01 0.002 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.949877e-01 0.002 1 1
Translation of Structural Proteins R-HSA-9694635 9.954246e-01 0.002 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 9.955120e-01 0.002 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.955120e-01 0.002 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.957551e-01 0.002 0 0
Nucleotide salvage R-HSA-8956321 9.957551e-01 0.002 0 0
Collagen degradation R-HSA-1442490 9.957551e-01 0.002 0 0
Interleukin-10 signaling R-HSA-6783783 9.958170e-01 0.002 0 0
ABC transporter disorders R-HSA-5619084 9.958170e-01 0.002 0 0
Activation of GABAB receptors R-HSA-991365 9.959816e-01 0.002 0 0
GABA B receptor activation R-HSA-977444 9.959816e-01 0.002 0 0
Platelet homeostasis R-HSA-418346 9.963468e-01 0.002 0 0
PPARA activates gene expression R-HSA-1989781 9.963970e-01 0.002 0 0
Defensins R-HSA-1461973 9.964020e-01 0.002 0 0
Methylation R-HSA-156581 9.967784e-01 0.001 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.967784e-01 0.001 0 0
Amyloid fiber formation R-HSA-977225 9.968079e-01 0.001 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.968562e-01 0.001 0 0
Stimuli-sensing channels R-HSA-2672351 9.968872e-01 0.001 0 0
Eukaryotic Translation Termination R-HSA-72764 9.971269e-01 0.001 0 0
Interferon gamma signaling R-HSA-877300 9.972594e-01 0.001 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.973613e-01 0.001 0 0
Metabolism of steroid hormones R-HSA-196071 9.976459e-01 0.001 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.976876e-01 0.001 0 0
O-linked glycosylation of mucins R-HSA-913709 9.978674e-01 0.001 0 0
Gluconeogenesis R-HSA-70263 9.979296e-01 0.001 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.979296e-01 0.001 0 0
Ribosome-associated quality control R-HSA-9948299 9.981098e-01 0.001 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.981463e-01 0.001 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.981463e-01 0.001 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.981514e-01 0.001 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.982642e-01 0.001 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.982642e-01 0.001 0 0
Azathioprine ADME R-HSA-9748787 9.983404e-01 0.001 0 0
Hedgehog 'on' state R-HSA-5632684 9.984158e-01 0.001 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.985141e-01 0.001 0 0
Cytosolic sulfonation of small molecules R-HSA-156584 9.985141e-01 0.001 0 0
Aspirin ADME R-HSA-9749641 9.987015e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.988246e-01 0.001 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.988335e-01 0.001 0 0
Iron uptake and transport R-HSA-917937 9.989362e-01 0.000 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.989367e-01 0.000 0 0
Translation R-HSA-72766 9.990280e-01 0.000 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.990309e-01 0.000 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.990309e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.990890e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.991169e-01 0.000 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.991452e-01 0.000 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.991452e-01 0.000 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.992670e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.993745e-01 0.000 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.993866e-01 0.000 0 0
Peroxisomal protein import R-HSA-9033241 9.993866e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.994497e-01 0.000 0 0
GABA receptor activation R-HSA-977443 9.994508e-01 0.000 0 0
Endogenous sterols R-HSA-211976 9.995084e-01 0.000 0 0
Mitochondrial protein import R-HSA-1268020 9.995599e-01 0.000 0 0
G alpha (q) signalling events R-HSA-416476 9.995935e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.996318e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.996472e-01 0.000 0 0
Xenobiotics R-HSA-211981 9.996472e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.996773e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.996855e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.996968e-01 0.000 0 0
Ion channel transport R-HSA-983712 9.997056e-01 0.000 0 0
Peptide chain elongation R-HSA-156902 9.997399e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.997469e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.997671e-01 0.000 1 0
Asparagine N-linked glycosylation R-HSA-446203 9.997796e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.998184e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.998184e-01 0.000 0 0
Protein localization R-HSA-9609507 9.998360e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.998374e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.998374e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.998374e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.998545e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.998697e-01 0.000 0 0
G alpha (s) signalling events R-HSA-418555 9.998782e-01 0.000 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.998956e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.998965e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.998965e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999060e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999234e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.999251e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.999251e-01 0.000 0 0
Cholesterol biosynthesis R-HSA-191273 9.999251e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999254e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.999309e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999342e-01 0.000 0 0
Selenocysteine synthesis R-HSA-2408557 9.999437e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.999463e-01 0.000 0 0
Viral mRNA Translation R-HSA-192823 9.999541e-01 0.000 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.999570e-01 0.000 1 0
Diseases of glycosylation R-HSA-3781865 9.999582e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999615e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999633e-01 0.000 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.999726e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999777e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999779e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.999799e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.999823e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999858e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999870e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.999898e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999916e-01 0.000 0 0
Potassium Channels R-HSA-1296071 9.999927e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999929e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999935e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999941e-01 0.000 0 0
Disease R-HSA-1643685 9.999949e-01 0.000 1 0
Infectious disease R-HSA-5663205 9.999956e-01 0.000 1 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999967e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.999968e-01 0.000 0 0
Selenoamino acid metabolism R-HSA-2408522 9.999972e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999973e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999984e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.999987e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999988e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999997e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999997e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999998e-01 0.000 0 0
Regulation of Complement cascade R-HSA-977606 9.999998e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999999e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999999e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999999e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999999e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999999e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999999e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Complement cascade R-HSA-166658 1.000000e+00 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.000000e+00 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Cell Cycle R-HSA-1640170 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 1 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Cell Cycle, Mitotic R-HSA-69278 2.220446e-16 15.654 0 0
Cellular response to heat stress R-HSA-3371556 5.551115e-16 15.256 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.309264e-14 13.637 1 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 3.008704e-14 13.522 0 0
Attenuation phase R-HSA-3371568 7.394085e-14 13.131 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.526557e-13 12.816 0 0
Separation of Sister Chromatids R-HSA-2467813 1.996181e-13 12.700 0 0
Axon guidance R-HSA-422475 2.778888e-13 12.556 0 0
HSF1-dependent transactivation R-HSA-3371571 4.044542e-13 12.393 0 0
HSF1 activation R-HSA-3371511 4.729550e-13 12.325 0 0
Nervous system development R-HSA-9675108 5.279110e-13 12.277 0 0
Mitotic Anaphase R-HSA-68882 1.432188e-12 11.844 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.536327e-12 11.814 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.697087e-12 11.770 0 0
Aggrephagy R-HSA-9646399 3.131384e-12 11.504 0 0
Cell-Cell communication R-HSA-1500931 3.260059e-12 11.487 0 0
Mitotic Prometaphase R-HSA-68877 5.786593e-12 11.238 0 0
PKR-mediated signaling R-HSA-9833482 1.317735e-11 10.880 1 1
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.660294e-11 10.780 0 0
Cell Cycle Checkpoints R-HSA-69620 1.621703e-11 10.790 0 0
Recycling pathway of L1 R-HSA-437239 8.184453e-11 10.087 0 0
Apoptotic execution phase R-HSA-75153 3.006054e-10 9.522 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 3.101773e-10 9.508 0 0
Transport of connexons to the plasma membrane R-HSA-190872 5.819815e-10 9.235 0 0
Selective autophagy R-HSA-9663891 6.085084e-10 9.216 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 6.667062e-10 9.176 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 6.500467e-10 9.187 0 0
HCMV Early Events R-HSA-9609690 6.946839e-10 9.158 0 0
Viral Infection Pathways R-HSA-9824446 1.066848e-09 8.972 1 0
Cap-dependent Translation Initiation R-HSA-72737 1.517586e-09 8.819 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.517586e-09 8.819 0 0
Metabolism of RNA R-HSA-8953854 1.806027e-09 8.743 0 0
Signal Transduction R-HSA-162582 1.855946e-09 8.731 1 0
Eukaryotic Translation Elongation R-HSA-156842 2.000963e-09 8.699 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.265197e-09 8.645 0 0
Cell junction organization R-HSA-446728 3.912978e-09 8.407 0 0
Formation of a pool of free 40S subunits R-HSA-72689 1.718534e-08 7.765 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.714394e-08 7.766 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.865751e-08 7.729 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 2.135474e-08 7.671 0 0
Influenza Infection R-HSA-168255 2.353844e-08 7.628 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.138286e-08 7.503 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 3.247149e-08 7.488 0 0
Mitotic Prophase R-HSA-68875 3.340008e-08 7.476 0 0
G2/M Checkpoints R-HSA-69481 4.415856e-08 7.355 0 0
Gap junction trafficking and regulation R-HSA-157858 8.683664e-08 7.061 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 9.530418e-08 7.021 0 0
Autophagy R-HSA-9612973 1.038177e-07 6.984 0 0
Peptide chain elongation R-HSA-156902 1.073799e-07 6.969 0 0
Interferon Signaling R-HSA-913531 1.780174e-07 6.750 1 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.858340e-07 6.731 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.858340e-07 6.731 0 0
Macroautophagy R-HSA-1632852 1.984592e-07 6.702 0 0
HCMV Infection R-HSA-9609646 3.381071e-07 6.471 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.511187e-07 6.455 1 0
SARS-CoV-2-host interactions R-HSA-9705683 3.576682e-07 6.447 1 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 3.597758e-07 6.444 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 3.727935e-07 6.429 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.802677e-07 6.420 0 0
Gap junction trafficking R-HSA-190828 3.961924e-07 6.402 0 0
L1CAM interactions R-HSA-373760 4.539096e-07 6.343 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 5.077366e-07 6.294 0 0
Apoptosis R-HSA-109581 6.314126e-07 6.200 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 6.382305e-07 6.195 0 0
G2/M DNA damage checkpoint R-HSA-69473 6.657240e-07 6.177 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 7.350002e-07 6.134 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 7.684088e-07 6.114 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 8.160040e-07 6.088 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 8.982300e-07 6.047 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 9.961900e-07 6.002 0 0
Meiotic synapsis R-HSA-1221632 1.034025e-06 5.985 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.232752e-06 5.909 0 0
Signaling by ROBO receptors R-HSA-376176 1.281574e-06 5.892 0 0
Translation initiation complex formation R-HSA-72649 1.318429e-06 5.880 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.363673e-06 5.865 0 0
Gap junction assembly R-HSA-190861 1.390582e-06 5.857 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.343719e-06 5.872 0 0
Kinesins R-HSA-983189 1.425942e-06 5.846 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.511731e-06 5.821 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.489094e-06 5.827 0 0
Membrane Trafficking R-HSA-199991 1.444826e-06 5.840 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.608704e-06 5.794 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.811793e-06 5.742 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.862033e-06 5.730 0 0
Cell-cell junction organization R-HSA-421270 1.859088e-06 5.731 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 2.110700e-06 5.676 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.206889e-06 5.656 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 2.223085e-06 5.653 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 2.805888e-06 5.552 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.066384e-06 5.513 0 0
Post NMDA receptor activation events R-HSA-438064 3.037039e-06 5.518 0 0
Cytokine Signaling in Immune system R-HSA-1280215 3.217289e-06 5.493 1 0
Adherens junctions interactions R-HSA-418990 3.247815e-06 5.488 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 3.313950e-06 5.480 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 3.487314e-06 5.458 0 0
Death Receptor Signaling R-HSA-73887 3.572563e-06 5.447 1 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 4.054386e-06 5.392 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 4.054386e-06 5.392 0 0
Mitotic Spindle Checkpoint R-HSA-69618 4.288506e-06 5.368 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 4.584923e-06 5.339 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 4.861359e-06 5.313 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 5.108845e-06 5.292 0 0
Eukaryotic Translation Termination R-HSA-72764 5.541066e-06 5.256 0 0
G2/M Transition R-HSA-69275 5.470131e-06 5.262 0 0
Cellular response to starvation R-HSA-9711097 5.854104e-06 5.233 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 6.157700e-06 5.211 0 0
Mitotic G2-G2/M phases R-HSA-453274 6.824395e-06 5.166 0 0
Signaling by EGFR R-HSA-177929 7.652452e-06 5.116 0 0
Nucleosome assembly R-HSA-774815 8.562354e-06 5.067 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 8.562354e-06 5.067 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 8.372254e-06 5.077 0 0
SARS-CoV-1 Infection R-HSA-9678108 8.530168e-06 5.069 0 0
Nuclear Envelope Breakdown R-HSA-2980766 9.466257e-06 5.024 0 0
Chaperone Mediated Autophagy R-HSA-9613829 9.571008e-06 5.019 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 9.571008e-06 5.019 1 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.073178e-05 4.969 1 1
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.117267e-05 4.952 1 0
Developmental Biology R-HSA-1266738 1.216923e-05 4.915 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.227586e-05 4.911 0 0
HIV Life Cycle R-HSA-162587 1.244104e-05 4.905 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.344817e-05 4.871 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.401075e-05 4.854 0 0
Selenocysteine synthesis R-HSA-2408557 1.411476e-05 4.850 0 0
Ribosome-associated quality control R-HSA-9948299 1.575113e-05 4.803 0 0
Viral mRNA Translation R-HSA-192823 1.895415e-05 4.722 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.929104e-05 4.715 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.944659e-05 4.711 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.944659e-05 4.711 0 0
Programmed Cell Death R-HSA-5357801 2.001031e-05 4.699 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 2.182587e-05 4.661 0 0
Processing of DNA double-strand break ends R-HSA-5693607 2.511725e-05 4.600 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 2.575903e-05 4.589 0 0
Protein ubiquitination R-HSA-8852135 2.732271e-05 4.563 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 3.390917e-05 4.470 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.827814e-05 4.417 0 0
Signaling by ALK in cancer R-HSA-9700206 3.827814e-05 4.417 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.880092e-05 4.411 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 4.335127e-05 4.363 1 1
Listeria monocytogenes entry into host cells R-HSA-8876384 4.065296e-05 4.391 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 3.990942e-05 4.399 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 4.714292e-05 4.327 0 0
Meiosis R-HSA-1500620 4.756569e-05 4.323 0 0
DNA Double-Strand Break Repair R-HSA-5693532 4.287073e-05 4.368 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 4.391656e-05 4.357 0 0
SARS-CoV Infections R-HSA-9679506 4.655441e-05 4.332 1 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 4.929784e-05 4.307 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 5.017128e-05 4.300 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 5.620208e-05 4.250 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 5.701391e-05 4.244 0 0
SARS-CoV-2 Infection R-HSA-9694516 5.868462e-05 4.231 1 0
MHC class II antigen presentation R-HSA-2132295 6.136254e-05 4.212 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 6.523371e-05 4.186 1 1
p75NTR signals via NF-kB R-HSA-193639 6.523371e-05 4.186 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 7.007248e-05 4.154 0 0
HDACs deacetylate histones R-HSA-3214815 7.169068e-05 4.145 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 7.349198e-05 4.134 0 0
NF-kB is activated and signals survival R-HSA-209560 7.349198e-05 4.134 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 7.349198e-05 4.134 0 0
HIV Infection R-HSA-162906 7.343347e-05 4.134 0 0
Homology Directed Repair R-HSA-5693538 8.115677e-05 4.091 0 0
ISG15 antiviral mechanism R-HSA-1169408 8.054599e-05 4.094 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 8.429097e-05 4.074 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 8.429097e-05 4.074 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 9.493678e-05 4.023 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 9.527145e-05 4.021 1 1
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.055836e-04 3.976 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 1.055836e-04 3.976 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.111983e-04 3.954 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.134162e-04 3.945 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.135338e-04 3.945 0 0
Chromatin organization R-HSA-4839726 1.175069e-04 3.930 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 1.374177e-04 3.862 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.367282e-04 3.864 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.312757e-04 3.882 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.227733e-04 3.911 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.255964e-04 3.901 0 0
COPI-mediated anterograde transport R-HSA-6807878 1.313649e-04 3.882 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.354701e-04 3.868 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.270971e-04 3.896 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.424625e-04 3.846 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.424625e-04 3.846 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 1.424625e-04 3.846 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.661180e-04 3.780 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.671462e-04 3.777 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.677427e-04 3.775 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 1.714882e-04 3.766 0 0
EPH-Ephrin signaling R-HSA-2682334 1.734987e-04 3.761 0 0
Signaling by ERBB2 R-HSA-1227986 1.750726e-04 3.757 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 1.774066e-04 3.751 0 0
Infectious disease R-HSA-5663205 1.861600e-04 3.730 1 0
DNA Double Strand Break Response R-HSA-5693606 1.873094e-04 3.727 0 0
Signaling by Hippo R-HSA-2028269 1.932472e-04 3.714 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.938444e-04 3.713 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.938444e-04 3.713 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.981259e-04 3.703 0 0
Interleukin-12 family signaling R-HSA-447115 2.000728e-04 3.699 0 0
Packaging Of Telomere Ends R-HSA-171306 2.299834e-04 3.638 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.149242e-04 3.668 0 0
Gene Silencing by RNA R-HSA-211000 2.397609e-04 3.620 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 2.507780e-04 3.601 0 0
Chromatin modifying enzymes R-HSA-3247509 2.565953e-04 3.591 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.586988e-04 3.587 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 2.622328e-04 3.581 0 0
Interleukin-12 signaling R-HSA-9020591 2.622328e-04 3.581 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.018853e-04 3.520 0 0
Cellular Senescence R-HSA-2559583 3.126016e-04 3.505 0 0
Striated Muscle Contraction R-HSA-390522 3.138947e-04 3.503 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.161669e-04 3.500 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 3.161669e-04 3.500 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 3.223189e-04 3.492 0 0
mRNA Splicing R-HSA-72172 3.282624e-04 3.484 0 0
Late Phase of HIV Life Cycle R-HSA-162599 3.335872e-04 3.477 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 3.400782e-04 3.468 0 0
Ub-specific processing proteases R-HSA-5689880 3.430641e-04 3.465 0 0
RNA Polymerase I Transcription R-HSA-73864 3.485111e-04 3.458 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 3.580658e-04 3.446 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 3.580658e-04 3.446 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 3.620703e-04 3.441 1 1
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.861288e-04 3.413 0 0
Deubiquitination R-HSA-5688426 3.526516e-04 3.453 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.861288e-04 3.413 0 0
Nuclear import of Rev protein R-HSA-180746 3.899819e-04 3.409 0 0
Spry regulation of FGF signaling R-HSA-1295596 3.580658e-04 3.446 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.861288e-04 3.413 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 3.580658e-04 3.446 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 4.097113e-04 3.388 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 3.899819e-04 3.409 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 4.356615e-04 3.361 1 1
snRNP Assembly R-HSA-191859 4.374159e-04 3.359 0 0
Metabolism of non-coding RNA R-HSA-194441 4.374159e-04 3.359 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 4.432294e-04 3.353 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 4.432294e-04 3.353 0 0
Signaling downstream of RAS mutants R-HSA-9649948 4.432294e-04 3.353 0 0
Signaling by RAS mutants R-HSA-6802949 4.432294e-04 3.353 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.536574e-04 3.343 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 4.543891e-04 3.343 0 0
Signaling by MET R-HSA-6806834 4.584951e-04 3.339 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 4.584951e-04 3.339 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 4.728241e-04 3.325 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 4.728241e-04 3.325 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 4.810918e-04 3.318 0 0
Negative regulation of MET activity R-HSA-6807004 4.838329e-04 3.315 0 0
Nephrin family interactions R-HSA-373753 4.838329e-04 3.315 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.846635e-04 3.315 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.932332e-04 3.307 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.932332e-04 3.307 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.932332e-04 3.307 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.932332e-04 3.307 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.932332e-04 3.307 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.932332e-04 3.307 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.932332e-04 3.307 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.932332e-04 3.307 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.932332e-04 3.307 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.932332e-04 3.307 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.932332e-04 3.307 0 0
Chaperonin-mediated protein folding R-HSA-390466 5.121453e-04 3.291 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 5.150251e-04 3.288 0 0
Signaling by RAF1 mutants R-HSA-9656223 5.660646e-04 3.247 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 5.907747e-04 3.229 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 5.907747e-04 3.229 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 6.798121e-04 3.168 0 0
Chromosome Maintenance R-HSA-73886 6.136308e-04 3.212 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 6.326220e-04 3.199 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 6.072842e-04 3.217 0 0
IRAK1 recruits IKK complex R-HSA-937039 6.608774e-04 3.180 1 1
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 6.608774e-04 3.180 1 1
p75NTR recruits signalling complexes R-HSA-209543 6.608774e-04 3.180 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 6.924165e-04 3.160 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 7.087223e-04 3.150 0 0
Signaling by EGFR in Cancer R-HSA-1643713 7.105669e-04 3.148 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 7.176938e-04 3.144 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 7.176938e-04 3.144 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 7.322865e-04 3.135 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.711345e-04 3.113 0 0
MyD88-independent TLR4 cascade R-HSA-166166 7.856405e-04 3.105 1 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.856405e-04 3.105 1 0
Semaphorin interactions R-HSA-373755 8.016789e-04 3.096 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 8.036613e-04 3.095 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 8.060447e-04 3.094 0 0
Defective pyroptosis R-HSA-9710421 8.122238e-04 3.090 0 0
Host Interactions of HIV factors R-HSA-162909 8.311429e-04 3.080 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 8.684207e-04 3.061 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 8.916726e-04 3.050 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 8.940794e-04 3.049 1 1
RNA Polymerase I Promoter Opening R-HSA-73728 8.940794e-04 3.049 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 9.008633e-04 3.045 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 9.008633e-04 3.045 0 0
Activation of ATR in response to replication stress R-HSA-176187 9.008633e-04 3.045 0 0
Regulation of CDH1 Function R-HSA-9764561 9.118066e-04 3.040 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 9.206648e-04 3.036 0 0
Vesicle-mediated transport R-HSA-5653656 9.715659e-04 3.013 0 0
Signaling by VEGF R-HSA-194138 1.010892e-03 2.995 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.041717e-03 2.982 1 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.044654e-03 2.981 0 0
Protein folding R-HSA-391251 1.057130e-03 2.976 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 1.100331e-03 2.958 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.100331e-03 2.958 0 0
ESR-mediated signaling R-HSA-8939211 1.106863e-03 2.956 0 0
HATs acetylate histones R-HSA-3214847 1.113925e-03 2.953 0 0
Josephin domain DUBs R-HSA-5689877 1.210015e-03 2.917 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.210015e-03 2.917 0 0
Ephrin signaling R-HSA-3928664 1.215711e-03 2.915 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.221476e-03 2.913 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.245809e-03 2.905 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 1.249617e-03 2.903 1 0
Diseases of Immune System R-HSA-5260271 1.249617e-03 2.903 1 0
Amyloid fiber formation R-HSA-977225 1.312295e-03 2.882 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 1.583331e-03 2.800 0 0
DNA methylation R-HSA-5334118 1.378088e-03 2.861 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 1.479682e-03 2.830 1 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 1.578151e-03 2.802 1 1
Co-inhibition by PD-1 R-HSA-389948 1.548613e-03 2.810 0 0
rRNA processing R-HSA-72312 1.417145e-03 2.849 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.694377e-03 2.771 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.583496e-03 2.800 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.457751e-03 2.836 1 1
Diseases of programmed cell death R-HSA-9645723 1.405680e-03 2.852 0 0
Signaling by Interleukins R-HSA-449147 1.407877e-03 2.851 1 0
Interleukin-37 signaling R-HSA-9008059 1.689859e-03 2.772 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.696624e-03 2.770 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.755614e-03 2.756 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.755614e-03 2.756 0 0
MAP2K and MAPK activation R-HSA-5674135 1.759878e-03 2.755 0 0
DNA Repair R-HSA-73894 1.764601e-03 2.753 0 0
Intraflagellar transport R-HSA-5620924 1.842807e-03 2.735 0 0
DNA Replication R-HSA-69306 1.846557e-03 2.734 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.857782e-03 2.731 0 0
Adaptive Immune System R-HSA-1280218 2.021250e-03 2.694 1 0
EGFR downregulation R-HSA-182971 2.056387e-03 2.687 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 2.072875e-03 2.683 0 0
Depyrimidination R-HSA-73928 2.072875e-03 2.683 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.121896e-03 2.673 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.121896e-03 2.673 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 2.172595e-03 2.663 0 0
Regulation of PTEN localization R-HSA-8948747 2.177255e-03 2.662 0 0
Selenoamino acid metabolism R-HSA-2408522 2.284625e-03 2.641 0 0
Cleavage of the damaged purine R-HSA-110331 2.295068e-03 2.639 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 2.332147e-03 2.632 1 1
Regulation of PD-L1(CD274) expression R-HSA-9909648 2.389083e-03 2.622 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 2.463644e-03 2.608 0 0
IKBKB deficiency causes SCID R-HSA-5602636 2.559531e-03 2.592 1 1
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027 2.559531e-03 2.592 1 1
Myogenesis R-HSA-525793 2.600214e-03 2.585 0 0
Depurination R-HSA-73927 2.717796e-03 2.566 0 0
MITF-M-dependent gene expression R-HSA-9856651 2.824449e-03 2.549 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.830642e-03 2.548 0 0
Meiotic recombination R-HSA-912446 2.864602e-03 2.543 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 2.980986e-03 2.526 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 2.980986e-03 2.526 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 3.176328e-03 2.498 0 0
Regulation of TP53 Activity R-HSA-5633007 3.197505e-03 2.495 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 3.233531e-03 2.490 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 3.263478e-03 2.486 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 3.263478e-03 2.486 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 3.263478e-03 2.486 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 3.361938e-03 2.473 0 0
VLDLR internalisation and degradation R-HSA-8866427 3.371265e-03 2.472 0 0
Immune System R-HSA-168256 3.537444e-03 2.451 1 0
Reproduction R-HSA-1474165 3.563457e-03 2.448 0 0
TCR signaling R-HSA-202403 3.698979e-03 2.432 1 0
Regulation of T cell activation by CD28 family R-HSA-388841 3.700170e-03 2.432 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 3.755707e-03 2.425 0 0
Muscle contraction R-HSA-397014 3.761826e-03 2.425 0 0
Smooth Muscle Contraction R-HSA-445355 3.773142e-03 2.423 0 0
Regulation of TNFR1 signaling R-HSA-5357905 3.811937e-03 2.419 1 1
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.811937e-03 2.419 0 0
mTORC1-mediated signalling R-HSA-166208 4.009429e-03 2.397 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 4.009429e-03 2.397 0 0
Signaling by NOTCH R-HSA-157118 4.125661e-03 2.385 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.307838e-03 2.366 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 4.374288e-03 2.359 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 4.374288e-03 2.359 0 0
Gene expression (Transcription) R-HSA-74160 4.392299e-03 2.357 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 4.506841e-03 2.346 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 4.620284e-03 2.335 1 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 4.956006e-03 2.305 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 4.956006e-03 2.305 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 4.959142e-03 2.305 1 1
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 6.520526e-03 2.186 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 5.901787e-03 2.229 0 0
Regulation of signaling by CBL R-HSA-912631 6.196121e-03 2.208 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 6.520526e-03 2.186 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 5.984518e-03 2.223 0 0
Clathrin-mediated endocytosis R-HSA-8856828 5.986135e-03 2.223 0 0
TNF signaling R-HSA-75893 5.560193e-03 2.255 1 0
Regulation of KIT signaling R-HSA-1433559 5.901787e-03 2.229 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.209756e-03 2.207 0 0
Ovarian tumor domain proteases R-HSA-5689896 6.767360e-03 2.170 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 5.979766e-03 2.223 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 6.767360e-03 2.170 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 6.748182e-03 2.171 0 0
NRIF signals cell death from the nucleus R-HSA-205043 5.901787e-03 2.229 0 0
Signaling by FGFR2 R-HSA-5654738 6.376707e-03 2.195 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 6.767360e-03 2.170 0 0
Translation R-HSA-72766 5.480532e-03 2.261 0 0
Negative regulation of MAPK pathway R-HSA-5675221 5.076901e-03 2.294 0 0
Pexophagy R-HSA-9664873 6.520526e-03 2.186 0 0
Signaling by TGFB family members R-HSA-9006936 5.939513e-03 2.226 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.943572e-03 2.226 1 0
Glycolysis R-HSA-70171 5.885096e-03 2.230 0 0
NRAGE signals death through JNK R-HSA-193648 5.560193e-03 2.255 0 0
Maturation of protein E R-HSA-9683683 5.979766e-03 2.223 0 0
Maturation of protein E R-HSA-9694493 5.979766e-03 2.223 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 6.911005e-03 2.160 0 0
Sema4D in semaphorin signaling R-HSA-400685 7.213457e-03 2.142 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 7.587604e-03 2.120 0 0
DCC mediated attractive signaling R-HSA-418885 7.587604e-03 2.120 0 0
EPHB-mediated forward signaling R-HSA-3928662 7.731032e-03 2.112 0 0
Netrin-1 signaling R-HSA-373752 7.731032e-03 2.112 0 0
ER to Golgi Anterograde Transport R-HSA-199977 7.984856e-03 2.098 0 0
Cilium Assembly R-HSA-5617833 8.131765e-03 2.090 0 0
mRNA 3'-end processing R-HSA-72187 8.439672e-03 2.074 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.439672e-03 2.074 0 0
Centrosome maturation R-HSA-380287 8.503332e-03 2.070 0 0
Base Excision Repair R-HSA-73884 8.579325e-03 2.067 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 8.795267e-03 2.056 1 1
Regulation of localization of FOXO transcription factors R-HSA-9614399 8.795267e-03 2.056 0 0
PECAM1 interactions R-HSA-210990 8.795267e-03 2.056 0 0
DAG and IP3 signaling R-HSA-1489509 8.821746e-03 2.054 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 8.821746e-03 2.054 0 0
TCF dependent signaling in response to WNT R-HSA-201681 9.123971e-03 2.040 0 0
Telomere Maintenance R-HSA-157579 9.275461e-03 2.033 0 0
Negative regulation of FLT3 R-HSA-9706369 9.595409e-03 2.018 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.827338e-03 2.008 0 0
Viral Messenger RNA Synthesis R-HSA-168325 9.982007e-03 2.001 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.010775e-02 1.995 1 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.010775e-02 1.995 1 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.010775e-02 1.995 1 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 1.040344e-02 1.983 0 0
MET interacts with TNS proteins R-HSA-8875513 1.040344e-02 1.983 0 0
MET activates PTPN11 R-HSA-8865999 1.040344e-02 1.983 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.070240e-02 1.971 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.100662e-02 1.958 0 0
Interleukin-1 family signaling R-HSA-446652 1.122050e-02 1.950 1 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 1.135459e-02 1.945 1 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 1.187705e-02 1.925 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.187705e-02 1.925 0 0
Disorders of Developmental Biology R-HSA-9675151 1.195546e-02 1.922 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.204876e-02 1.919 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.204876e-02 1.919 0 0
RAF activation R-HSA-5673000 1.216018e-02 1.915 0 0
Mitophagy R-HSA-5205647 1.216018e-02 1.915 0 0
MECP2 regulates transcription factors R-HSA-9022707 1.272553e-02 1.895 0 0
Signaling by WNT R-HSA-195721 1.273891e-02 1.895 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 1.340712e-02 1.873 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 1.340712e-02 1.873 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.394191e-02 1.856 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.394191e-02 1.856 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.394191e-02 1.856 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.394191e-02 1.856 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.394191e-02 1.856 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 1.394191e-02 1.856 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.394191e-02 1.856 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 1.409421e-02 1.851 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.414880e-02 1.849 0 0
DNA Damage Bypass R-HSA-73893 1.441329e-02 1.841 0 0
Toll-like Receptor Cascades R-HSA-168898 1.464888e-02 1.834 1 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 1.469676e-02 1.833 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 1.469676e-02 1.833 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.487778e-02 1.827 0 0
Disorders of Nervous System Development R-HSA-9697154 1.487778e-02 1.827 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.487778e-02 1.827 0 0
Pervasive developmental disorders R-HSA-9005895 1.487778e-02 1.827 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.487778e-02 1.827 0 0
S Phase R-HSA-69242 1.530969e-02 1.815 0 0
MTOR signalling R-HSA-165159 1.532600e-02 1.815 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.532600e-02 1.815 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.589768e-02 1.799 0 0
FLT3 signaling in disease R-HSA-9682385 1.603886e-02 1.795 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.638144e-02 1.786 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 1.642746e-02 1.784 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.666565e-02 1.778 1 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.670067e-02 1.777 0 0
Regulation of gap junction activity R-HSA-191650 1.685224e-02 1.773 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 1.685224e-02 1.773 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.685224e-02 1.773 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 1.700793e-02 1.769 1 1
Signaling by FGFR4 R-HSA-5654743 1.730638e-02 1.762 0 0
MET receptor recycling R-HSA-8875656 1.740109e-02 1.759 0 0
Formation of annular gap junctions R-HSA-196025 1.740109e-02 1.759 0 0
Modulation by Mtb of host immune system R-HSA-9637628 1.740109e-02 1.759 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.750005e-02 1.757 1 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.750005e-02 1.757 1 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.753163e-02 1.756 0 0
GAB1 signalosome R-HSA-180292 1.784663e-02 1.748 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 1.805233e-02 1.743 1 1
HDR through Homologous Recombination (HRR) R-HSA-5685942 1.845990e-02 1.734 0 0
Interleukin-6 signaling R-HSA-1059683 1.877030e-02 1.727 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.509413e-02 1.600 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.509413e-02 1.600 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 2.509413e-02 1.600 0 0
Gap junction degradation R-HSA-190873 2.302318e-02 1.638 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 2.843321e-02 1.546 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.547101e-02 1.594 0 0
Metalloprotease DUBs R-HSA-5689901 2.567815e-02 1.590 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.822747e-02 1.549 0 0
Generation of second messenger molecules R-HSA-202433 2.639517e-02 1.578 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.010898e-02 1.697 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.233348e-02 1.651 0 0
Neutrophil degranulation R-HSA-6798695 2.348052e-02 1.629 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.212998e-02 1.655 0 0
Translesion Synthesis by POLH R-HSA-110320 2.143037e-02 1.669 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 2.958713e-02 1.529 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 2.212998e-02 1.655 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 2.212998e-02 1.655 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 2.302318e-02 1.638 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 2.327888e-02 1.633 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.958713e-02 1.529 0 0
GP1b-IX-V activation signalling R-HSA-430116 2.302318e-02 1.638 0 0
Rap1 signalling R-HSA-392517 2.143037e-02 1.669 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 2.150474e-02 1.667 1 0
Protein methylation R-HSA-8876725 2.843321e-02 1.546 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 2.150474e-02 1.667 1 0
MAPK family signaling cascades R-HSA-5683057 2.044457e-02 1.689 0 0
The NLRP3 inflammasome R-HSA-844456 2.143037e-02 1.669 0 0
Glycogen metabolism R-HSA-8982491 2.639517e-02 1.578 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 2.483505e-02 1.605 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 2.374280e-02 1.624 1 0
Signaling by FGFR3 R-HSA-5654741 2.182406e-02 1.661 0 0
Unwinding of DNA R-HSA-176974 2.302318e-02 1.638 0 0
MAP kinase activation R-HSA-450294 2.243467e-02 1.649 1 0
RNA Polymerase II Transcription Termination R-HSA-73856 2.243467e-02 1.649 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 2.546377e-02 1.594 1 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 2.173833e-02 1.663 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 2.958713e-02 1.529 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 2.855229e-02 1.544 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 2.261598e-02 1.646 1 0
G alpha (12/13) signalling events R-HSA-416482 2.378225e-02 1.624 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 2.501718e-02 1.602 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.656787e-02 1.576 0 0
Signal regulatory protein family interactions R-HSA-391160 2.327888e-02 1.633 0 0
tRNA processing in the nucleus R-HSA-6784531 2.467847e-02 1.608 0 0
Glucose metabolism R-HSA-70326 2.765891e-02 1.558 0 0
FLT3 Signaling R-HSA-9607240 2.958713e-02 1.529 0 0
Hedgehog 'off' state R-HSA-5610787 2.311421e-02 1.636 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 2.959630e-02 1.529 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 2.963156e-02 1.528 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 2.963156e-02 1.528 0 0
2-LTR circle formation R-HSA-164843 2.963156e-02 1.528 0 0
Early Phase of HIV Life Cycle R-HSA-162594 2.998897e-02 1.523 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.012151e-02 1.521 0 0
Platelet degranulation R-HSA-114608 3.158940e-02 1.500 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 3.192718e-02 1.496 0 0
NOD1/2 Signaling Pathway R-HSA-168638 3.192718e-02 1.496 1 1
Activation of HOX genes during differentiation R-HSA-5619507 3.292486e-02 1.482 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 3.292486e-02 1.482 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.330082e-02 1.478 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 3.330082e-02 1.478 1 0
RNA Polymerase II Transcription R-HSA-73857 3.354757e-02 1.474 0 0
HIV elongation arrest and recovery R-HSA-167287 3.389847e-02 1.470 0 0
Pausing and recovery of HIV elongation R-HSA-167290 3.389847e-02 1.470 0 0
Prolonged ERK activation events R-HSA-169893 3.425727e-02 1.465 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.500194e-02 1.456 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 3.513673e-02 1.454 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 3.513673e-02 1.454 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 3.513673e-02 1.454 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 3.513673e-02 1.454 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 3.513673e-02 1.454 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 3.513673e-02 1.454 1 1
Cellular responses to mechanical stimuli R-HSA-9855142 3.551188e-02 1.450 1 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 3.649531e-02 1.438 0 0
Ca-dependent events R-HSA-111996 3.676052e-02 1.435 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 3.676052e-02 1.435 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 3.702542e-02 1.431 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 3.702542e-02 1.431 0 0
Signaling by FGFR R-HSA-190236 3.717431e-02 1.430 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 3.725134e-02 1.429 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 3.828948e-02 1.417 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.859710e-02 1.413 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 3.859710e-02 1.413 0 0
Late endosomal microautophagy R-HSA-9615710 3.859710e-02 1.413 0 0
Termination of translesion DNA synthesis R-HSA-5656169 3.859710e-02 1.413 0 0
Platelet calcium homeostasis R-HSA-418360 3.859710e-02 1.413 0 0
CaM pathway R-HSA-111997 4.028994e-02 1.395 0 0
Calmodulin induced events R-HSA-111933 4.028994e-02 1.395 0 0
RET signaling R-HSA-8853659 4.028994e-02 1.395 0 0
FGFR2 alternative splicing R-HSA-6803529 4.052465e-02 1.392 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 4.052465e-02 1.392 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 4.052465e-02 1.392 0 0
TBC/RABGAPs R-HSA-8854214 4.075832e-02 1.390 0 0
Signaling by SCF-KIT R-HSA-1433557 4.075832e-02 1.390 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 4.076919e-02 1.390 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 4.076919e-02 1.390 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 4.076919e-02 1.390 0 0
Transcription of the HIV genome R-HSA-167172 4.169734e-02 1.380 0 0
Regulation of PTEN gene transcription R-HSA-8943724 4.317287e-02 1.365 0 0
Activation of the pre-replicative complex R-HSA-68962 4.370290e-02 1.359 0 0
Activation of BH3-only proteins R-HSA-114452 4.370290e-02 1.359 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.434765e-02 1.353 0 0
Hemostasis R-HSA-109582 4.508305e-02 1.346 0 0
Activation of RAC1 R-HSA-428540 4.589366e-02 1.338 0 0
Integration of provirus R-HSA-162592 4.589366e-02 1.338 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 4.589366e-02 1.338 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.589366e-02 1.338 0 0
Syndecan interactions R-HSA-3000170 4.656882e-02 1.332 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 4.694326e-02 1.328 0 0
Nef and signal transduction R-HSA-164944 4.694326e-02 1.328 0 0
PLC beta mediated events R-HSA-112043 4.697496e-02 1.328 0 0
Glycogen storage diseases R-HSA-3229121 4.798119e-02 1.319 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.851298e-02 1.314 0 0
Interleukin-17 signaling R-HSA-448424 4.884710e-02 1.311 1 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 4.922477e-02 1.308 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 4.922477e-02 1.308 0 0
Developmental Cell Lineages R-HSA-9734767 4.957004e-02 1.305 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.961160e-02 1.304 0 0
mRNA Editing: A to I Conversion R-HSA-75064 4.969595e-02 1.304 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 4.969595e-02 1.304 0 0
C6 deamination of adenosine R-HSA-75102 4.969595e-02 1.304 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 4.969595e-02 1.304 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 4.969595e-02 1.304 0 0
MET promotes cell motility R-HSA-8875878 4.999563e-02 1.301 0 0
Disease R-HSA-1643685 5.093619e-02 1.293 1 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 5.314306e-02 1.275 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 5.447887e-02 1.264 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 5.447887e-02 1.264 0 0
DNA strand elongation R-HSA-69190 5.516976e-02 1.258 0 0
Plasma lipoprotein clearance R-HSA-8964043 5.536963e-02 1.257 0 0
Repression of WNT target genes R-HSA-4641265 5.555667e-02 1.255 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 5.555667e-02 1.255 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 5.555667e-02 1.255 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 5.761100e-02 1.239 0 0
Signaling by NOTCH3 R-HSA-9012852 5.761100e-02 1.239 0 0
ER-Phagosome pathway R-HSA-1236974 5.822422e-02 1.235 1 1
EPH-ephrin mediated repulsion of cells R-HSA-3928665 5.964635e-02 1.224 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 6.044257e-02 1.219 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 6.044257e-02 1.219 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 6.044257e-02 1.219 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 6.044257e-02 1.219 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 6.044257e-02 1.219 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.107251e-02 1.214 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 6.109801e-02 1.214 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 6.109801e-02 1.214 0 0
Regulation of necroptotic cell death R-HSA-5675482 6.154300e-02 1.211 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 6.154300e-02 1.211 0 0
Nucleotide Excision Repair R-HSA-5696398 6.173137e-02 1.209 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 6.255177e-02 1.204 0 0
Signaling by FGFR1 R-HSA-5654736 6.255177e-02 1.204 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 6.255177e-02 1.204 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 6.622668e-02 1.179 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 6.622668e-02 1.179 0 0
Frs2-mediated activation R-HSA-170968 6.622668e-02 1.179 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 6.622668e-02 1.179 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 6.790058e-02 1.168 0 0
IRE1alpha activates chaperones R-HSA-381070 7.044073e-02 1.152 0 0
Dual incision in TC-NER R-HSA-6782135 7.323208e-02 1.135 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 7.385342e-02 1.132 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 7.385342e-02 1.132 0 0
Signal transduction by L1 R-HSA-445144 7.385342e-02 1.132 0 0
Glycogen synthesis R-HSA-3322077 7.385342e-02 1.132 0 0
G-protein mediated events R-HSA-112040 7.456971e-02 1.127 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 7.522304e-02 1.124 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 7.553753e-02 1.122 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 7.553753e-02 1.122 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 7.553753e-02 1.122 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 7.553753e-02 1.122 0 0
Dual Incision in GG-NER R-HSA-5696400 7.558520e-02 1.122 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 7.558520e-02 1.122 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 7.558520e-02 1.122 0 0
Calnexin/calreticulin cycle R-HSA-901042 7.558520e-02 1.122 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 7.608553e-02 1.119 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 7.608553e-02 1.119 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 7.608553e-02 1.119 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 7.787932e-02 1.109 0 0
Interleukin-1 signaling R-HSA-9020702 7.854854e-02 1.105 1 1
MAPK1/MAPK3 signaling R-HSA-5684996 7.961153e-02 1.099 0 0
Rab regulation of trafficking R-HSA-9007101 8.020539e-02 1.096 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 8.325482e-02 1.080 0 0
Oncogene Induced Senescence R-HSA-2559585 8.325482e-02 1.080 0 0
Basigin interactions R-HSA-210991 8.387416e-02 1.076 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 8.387416e-02 1.076 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 8.387416e-02 1.076 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 8.387416e-02 1.076 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 8.474968e-02 1.072 0 0
Inflammasomes R-HSA-622312 8.480404e-02 1.072 0 0
XBP1(S) activates chaperone genes R-HSA-381038 8.512006e-02 1.070 0 0
Organelle biogenesis and maintenance R-HSA-1852241 9.007877e-02 1.045 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 9.008523e-02 1.045 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 9.048086e-02 1.043 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 9.048086e-02 1.043 0 0
Translesion synthesis by REV1 R-HSA-110312 9.048086e-02 1.043 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 1.623215e-01 0.790 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.623215e-01 0.790 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 1.623215e-01 0.790 0 0
TICAM1 deficiency - HSE R-HSA-5602566 1.623215e-01 0.790 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.623215e-01 0.790 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.623215e-01 0.790 0 0
Defective GALM causes GALAC4 R-HSA-9931929 1.623215e-01 0.790 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 1.623215e-01 0.790 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 9.982213e-02 1.001 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 9.982213e-02 1.001 0 0
IRS activation R-HSA-74713 1.284639e-01 0.891 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 1.284639e-01 0.891 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 9.211215e-02 1.036 0 0
ARMS-mediated activation R-HSA-170984 9.211215e-02 1.036 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 9.211215e-02 1.036 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 9.211215e-02 1.036 0 0
Calcineurin activates NFAT R-HSA-2025928 9.211215e-02 1.036 0 0
ALK mutants bind TKIs R-HSA-9700645 9.211215e-02 1.036 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 1.587186e-01 0.799 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.587186e-01 0.799 0 0
MAPK3 (ERK1) activation R-HSA-110056 1.100373e-01 0.958 0 0
Translesion synthesis by POLI R-HSA-5656121 1.039895e-01 0.983 0 0
Phosphorylation of the APC/C R-HSA-176412 1.039895e-01 0.983 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.039895e-01 0.983 0 0
Signaling by GSK3beta mutants R-HSA-5339716 1.493860e-01 0.826 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.183565e-01 0.927 0 0
Translesion synthesis by POLK R-HSA-5655862 1.183565e-01 0.927 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 1.705253e-01 0.768 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 1.705253e-01 0.768 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 1.705253e-01 0.768 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 1.705253e-01 0.768 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 1.705253e-01 0.768 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.038128e-01 0.984 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 1.660436e-01 0.780 0 0
Long-term potentiation R-HSA-9620244 1.437076e-01 0.843 0 0
Tight junction interactions R-HSA-420029 1.437076e-01 0.843 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 1.181773e-01 0.927 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 1.716753e-01 0.765 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.716753e-01 0.765 0 0
HIV Transcription Elongation R-HSA-167169 1.279343e-01 0.893 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 1.279343e-01 0.893 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 1.279343e-01 0.893 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 1.112579e-01 0.954 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 1.198422e-01 0.921 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 1.781989e-01 0.749 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 1.494441e-01 0.826 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.368818e-01 0.864 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 9.155865e-02 1.038 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.088223e-01 0.963 0 0
TGFBR3 expression R-HSA-9839394 1.437076e-01 0.843 0 0
Integrin signaling R-HSA-354192 1.360778e-01 0.866 0 0
Regulation of CDH11 function R-HSA-9762292 1.100373e-01 0.958 0 0
Regulation of mitotic cell cycle R-HSA-453276 1.685827e-01 0.773 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 1.685827e-01 0.773 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 1.587186e-01 0.799 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 9.135406e-02 1.039 0 0
Trafficking of AMPA receptors R-HSA-399719 1.140818e-01 0.943 0 0
Orc1 removal from chromatin R-HSA-68949 1.677053e-01 0.775 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 1.181773e-01 0.927 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.587375e-01 0.799 1 0
Signaling by Nuclear Receptors R-HSA-9006931 1.276703e-01 0.894 0 0
NADE modulates death signalling R-HSA-205025 9.982213e-02 1.001 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 1.335276e-01 0.874 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 1.494441e-01 0.826 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.200591e-01 0.921 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 1.660436e-01 0.780 0 0
Regulated Necrosis R-HSA-5218859 1.427281e-01 0.845 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.813703e-01 0.741 1 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 1.039895e-01 0.983 0 0
Diseases of mitotic cell cycle R-HSA-9675126 1.248423e-01 0.904 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 1.574357e-01 0.803 0 0
Degradation of CDH1 R-HSA-9766229 1.380250e-01 0.860 0 0
Synthesis of DNA R-HSA-69239 1.136925e-01 0.944 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 1.724386e-01 0.763 0 0
Response of endothelial cells to shear stress R-HSA-9860931 9.261929e-02 1.033 1 0
Interleukin-6 family signaling R-HSA-6783589 1.305261e-01 0.884 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 9.457284e-02 1.024 0 0
Effects of PIP2 hydrolysis R-HSA-114508 1.477696e-01 0.830 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 1.179237e-01 0.928 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 9.293837e-02 1.032 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.060067e-01 0.975 1 0
PCP/CE pathway R-HSA-4086400 1.473153e-01 0.832 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 9.404955e-02 1.027 0 0
Signalling to ERKs R-HSA-187687 1.724386e-01 0.763 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 9.404955e-02 1.027 0 0
Inhibition of PKR R-HSA-169131 1.623215e-01 0.790 0 0
MTF1 activates gene expression R-HSA-5660489 9.982213e-02 1.001 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 9.982213e-02 1.001 0 0
Regulation of IFNG signaling R-HSA-877312 1.705253e-01 0.768 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 1.335276e-01 0.874 0 0
Downstream signal transduction R-HSA-186763 1.140818e-01 0.943 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.735280e-01 0.761 0 0
Neurexins and neuroligins R-HSA-6794361 1.677053e-01 0.775 0 0
HCMV Late Events R-HSA-9610379 1.042911e-01 0.982 0 0
Downstream TCR signaling R-HSA-202424 1.072629e-01 0.970 1 1
Platelet sensitization by LDL R-HSA-432142 1.494441e-01 0.826 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 9.211215e-02 1.036 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 1.587186e-01 0.799 0 0
Antigen processing-Cross presentation R-HSA-1236975 1.193730e-01 0.923 1 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 1.380250e-01 0.860 0 0
Generic Transcription Pathway R-HSA-212436 1.203027e-01 0.920 0 0
RAS processing R-HSA-9648002 1.181773e-01 0.927 0 0
Signaling by NTRKs R-HSA-166520 1.075926e-01 0.968 0 0
Transmission across Chemical Synapses R-HSA-112315 1.724669e-01 0.763 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 9.982213e-02 1.001 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 1.587186e-01 0.799 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.705253e-01 0.768 1 1
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 1.335276e-01 0.874 1 1
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.360778e-01 0.866 0 0
Regulation of TP53 Degradation R-HSA-6804757 9.135406e-02 1.039 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.179237e-01 0.928 1 1
Potential therapeutics for SARS R-HSA-9679191 1.708367e-01 0.767 0 0
Neurodegenerative Diseases R-HSA-8863678 1.305261e-01 0.884 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.305261e-01 0.884 0 0
Signaling by NOTCH2 R-HSA-1980145 1.598972e-01 0.796 0 0
Signaling by ERBB4 R-HSA-1236394 1.175658e-01 0.930 0 0
STING mediated induction of host immune responses R-HSA-1834941 1.660436e-01 0.780 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.181773e-01 0.927 0 0
Co-inhibition by BTLA R-HSA-9927353 1.284639e-01 0.891 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.716753e-01 0.765 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.823146e-01 0.739 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.183565e-01 0.927 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 1.716753e-01 0.765 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 1.323248e-01 0.878 0 0
Signaling by Leptin R-HSA-2586552 1.100373e-01 0.958 0 0
Signaling by Hedgehog R-HSA-5358351 1.017068e-01 0.993 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.183565e-01 0.927 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 9.457284e-02 1.024 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.707402e-01 0.768 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.494441e-01 0.826 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 1.140818e-01 0.943 0 0
Suppression of phagosomal maturation R-HSA-9637687 1.574357e-01 0.803 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.380250e-01 0.860 0 0
Regulation of BACH1 activity R-HSA-9708530 1.039895e-01 0.983 0 0
Translation of Structural Proteins R-HSA-9683701 1.486084e-01 0.828 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 1.494441e-01 0.826 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 1.284639e-01 0.891 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.832616e-01 0.737 0 0
Co-inhibition by CTLA4 R-HSA-389513 1.832616e-01 0.737 0 0
Formation of definitive endoderm R-HSA-9823730 1.832616e-01 0.737 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.833850e-01 0.737 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.833850e-01 0.737 0 0
Signaling by PTK6 R-HSA-8848021 1.833850e-01 0.737 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 1.889729e-01 0.724 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 1.901075e-01 0.721 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 1.901075e-01 0.721 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.924527e-01 0.716 0 0
Formation of axial mesoderm R-HSA-9796292 1.924527e-01 0.716 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 1.924527e-01 0.716 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.942055e-01 0.712 0 0
Signaling by NOTCH4 R-HSA-9013694 1.964974e-01 0.707 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.996350e-01 0.700 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.997999e-01 0.699 1 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 2.010320e-01 0.697 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 2.010320e-01 0.697 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 2.015404e-01 0.696 0 0
Signaling by TGFBR3 R-HSA-9839373 2.063950e-01 0.685 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 2.065421e-01 0.685 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.110917e-01 0.676 0 0
Ion homeostasis R-HSA-5578775 2.113090e-01 0.675 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 2.123038e-01 0.673 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 2.126248e-01 0.672 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 2.150306e-01 0.667 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 2.150306e-01 0.667 0 0
Signaling by NOTCH1 R-HSA-1980143 2.161488e-01 0.665 0 0
Inositol phosphate metabolism R-HSA-1483249 2.162135e-01 0.665 0 0
DAP12 signaling R-HSA-2424491 2.170881e-01 0.663 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 2.170881e-01 0.663 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.192879e-01 0.659 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.192879e-01 0.659 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 2.192879e-01 0.659 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.192879e-01 0.659 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 2.192879e-01 0.659 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.192879e-01 0.659 0 0
Assembly Of The HIV Virion R-HSA-175474 2.192879e-01 0.659 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.192879e-01 0.659 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.192879e-01 0.659 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 2.222214e-01 0.653 0 0
TRIF-mediated programmed cell death R-HSA-2562578 2.222214e-01 0.653 0 0
SOS-mediated signalling R-HSA-112412 2.222214e-01 0.653 0 0
Disinhibition of SNARE formation R-HSA-114516 2.222214e-01 0.653 0 0
Recycling of eIF2:GDP R-HSA-72731 2.222214e-01 0.653 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 2.222214e-01 0.653 0 0
Netrin mediated repulsion signals R-HSA-418886 2.222214e-01 0.653 0 0
CHL1 interactions R-HSA-447041 2.222214e-01 0.653 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 2.222214e-01 0.653 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 2.222214e-01 0.653 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 2.222214e-01 0.653 0 0
Opioid Signalling R-HSA-111885 2.255379e-01 0.647 0 0
Signaling by ALK R-HSA-201556 2.262533e-01 0.645 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 2.265675e-01 0.645 0 0
PTEN Regulation R-HSA-6807070 2.273522e-01 0.643 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 2.329923e-01 0.633 0 0
Budding and maturation of HIV virion R-HSA-162588 2.329923e-01 0.633 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 2.333229e-01 0.632 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.333229e-01 0.632 0 0
MyD88 deficiency (TLR5) R-HSA-5602680 2.333229e-01 0.632 0 0
TRAF3 deficiency - HSE R-HSA-5602571 2.333229e-01 0.632 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.333229e-01 0.632 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.333229e-01 0.632 0 0
Nef mediated downregulation of CD28 cell surface expression R-HSA-164939 2.333229e-01 0.632 0 0
Manipulation of host energy metabolism R-HSA-9636667 2.333229e-01 0.632 0 0
Transport of connexins along the secretory pathway R-HSA-190827 2.333229e-01 0.632 0 0
Oligomerization of connexins into connexons R-HSA-190704 2.333229e-01 0.632 0 0
Breakdown of the nuclear lamina R-HSA-352238 2.333229e-01 0.632 0 0
NTRK3 as a dependence receptor R-HSA-9603505 2.333229e-01 0.632 0 0
Pyruvate metabolism R-HSA-70268 2.362829e-01 0.627 0 0
Notch-HLH transcription pathway R-HSA-350054 2.379624e-01 0.623 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 2.379624e-01 0.623 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.379624e-01 0.623 0 0
Processive synthesis on the lagging strand R-HSA-69183 2.381266e-01 0.623 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 2.381266e-01 0.623 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 2.381266e-01 0.623 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 2.404884e-01 0.619 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 2.404884e-01 0.619 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.473406e-01 0.607 0 0
G0 and Early G1 R-HSA-1538133 2.492124e-01 0.603 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.543418e-01 0.595 0 0
Type I hemidesmosome assembly R-HSA-446107 2.547124e-01 0.594 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 2.547124e-01 0.594 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 2.547124e-01 0.594 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 2.549812e-01 0.593 1 1
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.549812e-01 0.593 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 2.569894e-01 0.590 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 2.569894e-01 0.590 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 2.587315e-01 0.587 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 2.587315e-01 0.587 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 2.587315e-01 0.587 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 2.587315e-01 0.587 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 2.587315e-01 0.587 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 2.616146e-01 0.582 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 2.657077e-01 0.576 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 2.657077e-01 0.576 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 2.657077e-01 0.576 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 2.657077e-01 0.576 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 2.697038e-01 0.569 0 0
HIV Transcription Initiation R-HSA-167161 2.697038e-01 0.569 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 2.697038e-01 0.569 0 0
Signaling by FGFR1 in disease R-HSA-5655302 2.697038e-01 0.569 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 2.763040e-01 0.559 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 2.763040e-01 0.559 0 0
Signaling by PDGF R-HSA-186797 2.835720e-01 0.547 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 2.853757e-01 0.545 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.853757e-01 0.545 0 0
Lipophagy R-HSA-9613354 2.872861e-01 0.542 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 2.872861e-01 0.542 0 0
mRNA Editing R-HSA-75072 2.872861e-01 0.542 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 2.872861e-01 0.542 0 0
Regulated proteolysis of p75NTR R-HSA-193692 2.872861e-01 0.542 0 0
MAPK1 (ERK2) activation R-HSA-112411 2.872861e-01 0.542 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 2.872861e-01 0.542 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 2.872861e-01 0.542 0 0
Interleukin-1 processing R-HSA-448706 2.872861e-01 0.542 0 0
Cellular response to mitochondrial stress R-HSA-9840373 2.872861e-01 0.542 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 2.872861e-01 0.542 0 0
Ca2+ pathway R-HSA-4086398 2.934411e-01 0.532 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 2.958428e-01 0.529 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 2.983101e-01 0.525 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 2.983101e-01 0.525 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) R-HSA-5655799 2.983101e-01 0.525 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 2.983101e-01 0.525 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 2.983101e-01 0.525 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 2.983101e-01 0.525 0 0
Regulation of cortical dendrite branching R-HSA-8985801 2.983101e-01 0.525 0 0
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization R-HSA-180897 2.983101e-01 0.525 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 2.983101e-01 0.525 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 2.993613e-01 0.524 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 2.993613e-01 0.524 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 2.997252e-01 0.523 0 0
Neuronal System R-HSA-112316 3.044901e-01 0.516 0 0
Ion transport by P-type ATPases R-HSA-936837 3.089938e-01 0.510 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 3.092987e-01 0.510 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 3.092987e-01 0.510 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 3.092987e-01 0.510 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 3.092987e-01 0.510 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 3.092987e-01 0.510 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 3.092987e-01 0.510 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 3.092987e-01 0.510 0 0
Protein-protein interactions at synapses R-HSA-6794362 3.127232e-01 0.505 0 0
Cyclin D associated events in G1 R-HSA-69231 3.149680e-01 0.502 0 0
G1 Phase R-HSA-69236 3.149680e-01 0.502 0 0
MET activates PTK2 signaling R-HSA-8874081 3.155447e-01 0.501 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 3.155447e-01 0.501 0 0
Regulation of Apoptosis R-HSA-169911 3.164400e-01 0.500 0 0
PERK regulates gene expression R-HSA-381042 3.164400e-01 0.500 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.196952e-01 0.495 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 3.196952e-01 0.495 0 0
PI3K/AKT activation R-HSA-198203 3.196952e-01 0.495 0 0
Interleukin-27 signaling R-HSA-9020956 3.196952e-01 0.495 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 3.196952e-01 0.495 0 0
Signal attenuation R-HSA-74749 3.196952e-01 0.495 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 3.196952e-01 0.495 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 3.196952e-01 0.495 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 3.269662e-01 0.485 1 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 3.293237e-01 0.482 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 3.303284e-01 0.481 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 3.303284e-01 0.481 1 1
Platelet Aggregation (Plug Formation) R-HSA-76009 3.303284e-01 0.481 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 3.303284e-01 0.481 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 3.303284e-01 0.481 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 3.320786e-01 0.479 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.320786e-01 0.479 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 3.332803e-01 0.477 0 0
Apoptotic factor-mediated response R-HSA-111471 3.332803e-01 0.477 0 0
Mismatch Repair R-HSA-5358508 3.332803e-01 0.477 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 3.336346e-01 0.477 0 0
RNA Polymerase III Transcription R-HSA-74158 3.336346e-01 0.477 0 0
GPVI-mediated activation cascade R-HSA-114604 3.336346e-01 0.477 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 3.353509e-01 0.475 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.353509e-01 0.475 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 3.403550e-01 0.468 0 0
Translation of Structural Proteins R-HSA-9694635 3.415946e-01 0.466 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 3.457792e-01 0.461 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 3.457792e-01 0.461 0 0
Regulation of pyruvate metabolism R-HSA-9861718 3.457792e-01 0.461 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 3.481624e-01 0.458 0 0
Degradation of DVL R-HSA-4641258 3.509077e-01 0.455 0 0
Signaling by APC mutants R-HSA-4839744 3.517339e-01 0.454 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 3.517339e-01 0.454 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 3.517339e-01 0.454 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 3.517339e-01 0.454 0 0
Formation of the posterior neural plate R-HSA-9832991 3.517339e-01 0.454 0 0
Bicarbonate transporters R-HSA-425381 3.517339e-01 0.454 0 0
vRNP Assembly R-HSA-192905 3.517339e-01 0.454 0 0
Interleukin-2 signaling R-HSA-9020558 3.517339e-01 0.454 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 3.545033e-01 0.450 0 0
Platelet homeostasis R-HSA-418346 3.550824e-01 0.450 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 3.552054e-01 0.450 0 0
Formation of the Early Elongation Complex R-HSA-113418 3.552054e-01 0.450 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 3.572257e-01 0.447 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 3.572257e-01 0.447 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 3.572257e-01 0.447 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 3.577922e-01 0.446 0 0
PLC-gamma1 signalling R-HSA-167021 3.577922e-01 0.446 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 3.577922e-01 0.446 0 0
Axonal growth stimulation R-HSA-209563 3.577922e-01 0.446 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 3.577922e-01 0.446 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.577922e-01 0.446 0 0
Defective SLC7A7 causes lysinuric protein intolerance (LPI) R-HSA-5660862 3.577922e-01 0.446 0 0
Defective HPRT1 disrupts guanine and hypoxanthine salvage R-HSA-9734281 3.577922e-01 0.446 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.577922e-01 0.446 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 3.577922e-01 0.446 0 0
MET activates STAT3 R-HSA-8875791 3.577922e-01 0.446 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 3.577922e-01 0.446 0 0
Histamine receptors R-HSA-390650 3.577922e-01 0.446 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 3.577922e-01 0.446 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 3.607652e-01 0.443 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 3.607652e-01 0.443 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 3.607652e-01 0.443 0 0
G1/S Transition R-HSA-69206 3.607652e-01 0.443 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 3.610574e-01 0.442 0 0
Post-translational protein phosphorylation R-HSA-8957275 3.734243e-01 0.428 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 3.742328e-01 0.427 0 0
Signaling by Erythropoietin R-HSA-9006335 3.750550e-01 0.426 0 0
mRNA Capping R-HSA-72086 3.750550e-01 0.426 0 0
Regulation of gene expression in beta cells R-HSA-210745 3.750550e-01 0.426 0 0
Stimuli-sensing channels R-HSA-2672351 3.760855e-01 0.425 0 0
Co-stimulation by CD28 R-HSA-389356 3.768462e-01 0.424 0 0
Gluconeogenesis R-HSA-70263 3.768462e-01 0.424 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 3.810483e-01 0.419 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 3.810483e-01 0.419 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 3.810483e-01 0.419 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 3.810483e-01 0.419 0 0
Protein hydroxylation R-HSA-9629569 3.810483e-01 0.419 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 3.832321e-01 0.417 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 3.832321e-01 0.417 0 0
Signaling by AMER1 mutants R-HSA-4839748 3.832321e-01 0.417 0 0
Signaling by AXIN mutants R-HSA-4839735 3.832321e-01 0.417 0 0
Innate Immune System R-HSA-168249 3.843330e-01 0.415 1 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.855449e-01 0.414 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 3.948497e-01 0.404 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 3.948497e-01 0.404 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 4.028405e-01 0.395 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 4.028405e-01 0.395 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 4.028405e-01 0.395 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 4.046697e-01 0.393 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 4.046697e-01 0.393 0 0
Lagging Strand Synthesis R-HSA-69186 4.046697e-01 0.393 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 4.046697e-01 0.393 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.079638e-01 0.389 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 4.093417e-01 0.388 0 0
HCN channels R-HSA-1296061 4.122353e-01 0.385 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 4.122353e-01 0.385 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 4.122353e-01 0.385 0 0
Signaling by MAP2K mutants R-HSA-9652169 4.122353e-01 0.385 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 4.122353e-01 0.385 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 4.122353e-01 0.385 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 4.122353e-01 0.385 0 0
GABA synthesis R-HSA-888568 4.122353e-01 0.385 0 0
TNFR1-mediated ceramide production R-HSA-5626978 4.122353e-01 0.385 0 0
Dopamine receptors R-HSA-390651 4.122353e-01 0.385 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.140515e-01 0.383 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.140515e-01 0.383 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 4.140515e-01 0.383 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.140515e-01 0.383 0 0
Interleukin-35 Signalling R-HSA-8984722 4.140515e-01 0.383 0 0
Signaling by LTK R-HSA-9842663 4.140515e-01 0.383 0 0
Polymerase switching R-HSA-69091 4.140515e-01 0.383 0 0
Leading Strand Synthesis R-HSA-69109 4.140515e-01 0.383 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 4.200776e-01 0.377 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 4.200776e-01 0.377 0 0
Hedgehog ligand biogenesis R-HSA-5358346 4.234811e-01 0.373 0 0
Heme signaling R-HSA-9707616 4.256710e-01 0.371 0 0
Signaling by WNT in cancer R-HSA-4791275 4.340897e-01 0.362 0 0
Post-translational protein modification R-HSA-597592 4.361161e-01 0.360 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 4.372258e-01 0.359 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 4.389401e-01 0.358 0 0
Signaling by FGFR in disease R-HSA-1226099 4.402876e-01 0.356 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 4.402893e-01 0.356 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 4.440808e-01 0.353 0 0
Maturation of nucleoprotein R-HSA-9683610 4.440808e-01 0.353 0 0
Protein localization R-HSA-9609507 4.466218e-01 0.350 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 4.510349e-01 0.346 0 0
LDL clearance R-HSA-8964038 4.510349e-01 0.346 0 0
RSV-host interactions R-HSA-9833110 4.511176e-01 0.346 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 4.527360e-01 0.344 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 4.534511e-01 0.343 0 0
FGFR1 mutant receptor activation R-HSA-1839124 4.534511e-01 0.343 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 4.620659e-01 0.335 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.620659e-01 0.335 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 4.620659e-01 0.335 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 4.620659e-01 0.335 0 0
Suppression of autophagy R-HSA-9636569 4.620659e-01 0.335 0 0
Muscarinic acetylcholine receptors R-HSA-390648 4.620659e-01 0.335 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 4.620659e-01 0.335 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 4.620659e-01 0.335 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 4.620659e-01 0.335 0 0
UCH proteinases R-HSA-5689603 4.665202e-01 0.331 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 4.711428e-01 0.327 0 0
Interferon alpha/beta signaling R-HSA-909733 4.713670e-01 0.327 0 0
Resolution of D-Loop Structures R-HSA-5693537 4.725894e-01 0.326 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 4.725894e-01 0.326 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 4.725894e-01 0.326 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 4.725894e-01 0.326 0 0
Vpu mediated degradation of CD4 R-HSA-180534 4.725894e-01 0.326 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 4.732326e-01 0.325 0 0
Removal of the Flap Intermediate R-HSA-69166 4.732326e-01 0.325 0 0
Retrograde neurotrophin signalling R-HSA-177504 4.732326e-01 0.325 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 4.732326e-01 0.325 0 0
Signaling by FGFR4 in disease R-HSA-5655291 4.732326e-01 0.325 0 0
Malate-aspartate shuttle R-HSA-9856872 4.732326e-01 0.325 0 0
Non-canonical inflammasome activation R-HSA-9686114 4.732326e-01 0.325 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 4.736606e-01 0.325 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 4.736606e-01 0.325 0 0
Growth hormone receptor signaling R-HSA-982772 4.736606e-01 0.325 0 0
Ion channel transport R-HSA-983712 4.772024e-01 0.321 0 0
DAP12 interactions R-HSA-2172127 4.878597e-01 0.312 0 0
RMTs methylate histone arginines R-HSA-3214858 4.878597e-01 0.312 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 4.914707e-01 0.309 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 4.914707e-01 0.309 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 4.914707e-01 0.309 0 0
Mitochondrial RNA degradation R-HSA-9836573 4.958484e-01 0.305 0 0
Erythropoietin activates RAS R-HSA-9027284 5.014398e-01 0.300 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 5.014398e-01 0.300 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.014398e-01 0.300 0 0
Formation of the anterior neural plate R-HSA-9823739 5.014398e-01 0.300 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 5.014398e-01 0.300 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 5.020227e-01 0.299 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 5.043838e-01 0.297 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 5.043838e-01 0.297 0 0
Sensory processing of sound R-HSA-9659379 5.053319e-01 0.296 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 5.076746e-01 0.294 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 5.076746e-01 0.294 0 0
Toxicity of botulinum toxin type E (botE) R-HSA-5250992 5.076746e-01 0.294 0 0
Cam-PDE 1 activation R-HSA-111957 5.076746e-01 0.294 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 5.076746e-01 0.294 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 5.076746e-01 0.294 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.076746e-01 0.294 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 5.076746e-01 0.294 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 5.076746e-01 0.294 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 5.100644e-01 0.292 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 5.100644e-01 0.292 0 0
Metabolism of proteins R-HSA-392499 5.168840e-01 0.287 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 5.175567e-01 0.286 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 5.175567e-01 0.286 0 0
Acyl chain remodelling of PS R-HSA-1482801 5.175567e-01 0.286 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 5.206934e-01 0.283 0 0
Diseases of DNA repair R-HSA-9675135 5.206934e-01 0.283 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 5.283429e-01 0.277 0 0
Glycosphingolipid transport R-HSA-9845576 5.283429e-01 0.277 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.286531e-01 0.277 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 5.286531e-01 0.277 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.286531e-01 0.277 0 0
Virus Assembly and Release R-HSA-168268 5.286531e-01 0.277 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 5.336985e-01 0.273 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 5.387500e-01 0.269 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 5.387500e-01 0.269 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 5.387500e-01 0.269 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 5.387500e-01 0.269 0 0
TRP channels R-HSA-3295583 5.387500e-01 0.269 0 0
Adipogenesis R-HSA-9843745 5.393387e-01 0.268 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.438446e-01 0.265 0 0
Degradation of AXIN R-HSA-4641257 5.462815e-01 0.263 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 5.462815e-01 0.263 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 5.490660e-01 0.260 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 5.490660e-01 0.260 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 5.494189e-01 0.260 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 5.494189e-01 0.260 0 0
Signaling by LTK in cancer R-HSA-9842640 5.494189e-01 0.260 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.494189e-01 0.260 0 0
STAT5 Activation R-HSA-9645135 5.494189e-01 0.260 0 0
Autointegration results in viral DNA circles R-HSA-177539 5.494189e-01 0.260 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 5.494189e-01 0.260 0 0
CREB phosphorylation R-HSA-199920 5.494189e-01 0.260 0 0
MET Receptor Activation R-HSA-6806942 5.494189e-01 0.260 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 5.494189e-01 0.260 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 5.494189e-01 0.260 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 5.494189e-01 0.260 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 5.494189e-01 0.260 0 0
VLDL assembly R-HSA-8866423 5.494189e-01 0.260 0 0
HDL clearance R-HSA-8964011 5.494189e-01 0.260 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.548384e-01 0.256 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 5.548384e-01 0.256 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 5.548384e-01 0.256 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 5.548384e-01 0.256 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.548384e-01 0.256 0 0
Passive transport by Aquaporins R-HSA-432047 5.548384e-01 0.256 0 0
Response to metal ions R-HSA-5660526 5.548384e-01 0.256 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 5.593988e-01 0.252 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 5.593988e-01 0.252 0 0
Insulin processing R-HSA-264876 5.593988e-01 0.252 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 5.697590e-01 0.244 0 0
SLC transporter disorders R-HSA-5619102 5.714903e-01 0.243 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 5.754597e-01 0.240 1 0
Phase 0 - rapid depolarisation R-HSA-5576892 5.794788e-01 0.237 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 5.794788e-01 0.237 0 0
Pyroptosis R-HSA-5620971 5.794788e-01 0.237 0 0
Specification of primordial germ cells R-HSA-9827857 5.799742e-01 0.237 0 0
Uptake and function of anthrax toxins R-HSA-5210891 5.799742e-01 0.237 0 0
Pentose phosphate pathway R-HSA-71336 5.810554e-01 0.236 0 0
Stabilization of p53 R-HSA-69541 5.810554e-01 0.236 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 5.810554e-01 0.236 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 5.810554e-01 0.236 0 0
Mitochondrial protein import R-HSA-1268020 5.861128e-01 0.232 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 5.876259e-01 0.231 0 0
IFNG signaling activates MAPKs R-HSA-9732724 5.876259e-01 0.231 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 5.876259e-01 0.231 0 0
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974 5.876259e-01 0.231 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 5.876259e-01 0.231 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 5.876259e-01 0.231 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 5.876259e-01 0.231 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 5.876259e-01 0.231 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 5.876259e-01 0.231 0 0
VLDL clearance R-HSA-8964046 5.876259e-01 0.231 0 0
LDL remodeling R-HSA-8964041 5.876259e-01 0.231 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 5.876259e-01 0.231 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 5.876259e-01 0.231 0 0
The phototransduction cascade R-HSA-2514856 5.983938e-01 0.223 0 0
DARPP-32 events R-HSA-180024 5.989708e-01 0.223 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 5.989708e-01 0.223 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 5.989708e-01 0.223 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 5.997454e-01 0.222 0 0
Iron uptake and transport R-HSA-917937 6.015346e-01 0.221 0 0
Interferon gamma signaling R-HSA-877300 6.024698e-01 0.220 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 6.040503e-01 0.219 0 0
Polo-like kinase mediated events R-HSA-156711 6.040503e-01 0.219 0 0
PKA activation R-HSA-163615 6.040503e-01 0.219 0 0
Nephron development R-HSA-9831926 6.040503e-01 0.219 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 6.130612e-01 0.212 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 6.178602e-01 0.209 0 0
phospho-PLA2 pathway R-HSA-111995 6.225953e-01 0.206 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 6.225953e-01 0.206 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 6.225953e-01 0.206 0 0
Regulation by c-FLIP R-HSA-3371378 6.225953e-01 0.206 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 6.225953e-01 0.206 0 0
Adrenoceptors R-HSA-390696 6.225953e-01 0.206 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 6.225953e-01 0.206 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 6.225953e-01 0.206 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 6.225953e-01 0.206 0 0
Nucleotide salvage defects R-HSA-9734207 6.225953e-01 0.206 0 0
Dimerization of procaspase-8 R-HSA-69416 6.225953e-01 0.206 0 0
TGFBR3 PTM regulation R-HSA-9839383 6.225953e-01 0.206 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 6.225953e-01 0.206 0 0
Interleukin-23 signaling R-HSA-9020933 6.225953e-01 0.206 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 6.270657e-01 0.203 0 0
Germ layer formation at gastrulation R-HSA-9754189 6.270657e-01 0.203 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.270657e-01 0.203 0 0
Specification of the neural plate border R-HSA-9834899 6.270657e-01 0.203 0 0
Other interleukin signaling R-HSA-449836 6.270657e-01 0.203 0 0
Maturation of nucleoprotein R-HSA-9694631 6.270657e-01 0.203 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 6.274109e-01 0.202 0 0
Degradation of CRY and PER proteins R-HSA-9932298 6.302134e-01 0.201 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 6.302134e-01 0.201 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 6.302134e-01 0.201 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 6.302134e-01 0.201 0 0
Parasite infection R-HSA-9664407 6.328728e-01 0.199 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 6.328728e-01 0.199 0 0
Leishmania phagocytosis R-HSA-9664417 6.328728e-01 0.199 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 6.361364e-01 0.196 0 0
Molecules associated with elastic fibres R-HSA-2129379 6.361364e-01 0.196 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 6.457508e-01 0.190 0 0
ABC-family proteins mediated transport R-HSA-382556 6.484068e-01 0.188 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 6.490271e-01 0.188 0 0
Signaling by NODAL R-HSA-1181150 6.490271e-01 0.188 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 6.490271e-01 0.188 0 0
Creatine metabolism R-HSA-71288 6.490271e-01 0.188 0 0
Parasitic Infection Pathways R-HSA-9824443 6.536352e-01 0.185 0 0
Leishmania infection R-HSA-9658195 6.536352e-01 0.185 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 6.537927e-01 0.185 0 0
WNT mediated activation of DVL R-HSA-201688 6.546011e-01 0.184 0 0
CASP8 activity is inhibited R-HSA-5218900 6.546011e-01 0.184 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 6.546011e-01 0.184 0 0
Toxicity of botulinum toxin type A (botA) R-HSA-5250968 6.546011e-01 0.184 0 0
p75NTR regulates axonogenesis R-HSA-193697 6.546011e-01 0.184 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 6.546011e-01 0.184 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 6.546011e-01 0.184 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.546011e-01 0.184 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 6.546011e-01 0.184 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 6.546011e-01 0.184 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 6.546011e-01 0.184 0 0
G alpha (z) signalling events R-HSA-418597 6.551242e-01 0.184 0 0
Circadian clock R-HSA-9909396 6.584878e-01 0.181 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 6.699477e-01 0.174 0 0
G-protein beta:gamma signalling R-HSA-397795 6.708257e-01 0.173 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 6.708257e-01 0.173 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 6.725808e-01 0.172 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 6.755075e-01 0.170 0 0
Amine ligand-binding receptors R-HSA-375280 6.755075e-01 0.170 0 0
Folding of actin by CCT/TriC R-HSA-390450 6.838944e-01 0.165 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 6.838944e-01 0.165 0 0
Binding and entry of HIV virion R-HSA-173107 6.838944e-01 0.165 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 6.838944e-01 0.165 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 6.838944e-01 0.165 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 6.838944e-01 0.165 0 0
CASP4 inflammasome assembly R-HSA-9948001 6.838944e-01 0.165 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 6.838944e-01 0.165 0 0
Receptor Mediated Mitophagy R-HSA-8934903 6.838944e-01 0.165 0 0
Maturation of spike protein R-HSA-9683686 6.838944e-01 0.165 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 6.879010e-01 0.162 0 0
Attachment and Entry R-HSA-9694614 6.898460e-01 0.161 0 0
Mitochondrial calcium ion transport R-HSA-8949215 6.898460e-01 0.161 0 0
Extension of Telomeres R-HSA-180786 7.064514e-01 0.151 0 0
Peroxisomal protein import R-HSA-9033241 7.064514e-01 0.151 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 7.087450e-01 0.150 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 7.087450e-01 0.150 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 7.087450e-01 0.150 0 0
Signaling by KIT in disease R-HSA-9669938 7.087450e-01 0.150 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 7.087450e-01 0.150 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 7.105870e-01 0.148 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 7.105870e-01 0.148 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 7.107050e-01 0.148 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 7.107050e-01 0.148 0 0
Ionotropic activity of kainate receptors R-HSA-451306 7.107050e-01 0.148 0 0
Chylomicron assembly R-HSA-8963888 7.107050e-01 0.148 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 7.107050e-01 0.148 0 0
Suppression of apoptosis R-HSA-9635465 7.107050e-01 0.148 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.107050e-01 0.148 0 0
Dissolution of Fibrin Clot R-HSA-75205 7.107050e-01 0.148 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 7.181963e-01 0.144 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 7.181963e-01 0.144 0 0
tRNA Aminoacylation R-HSA-379724 7.184107e-01 0.144 0 0
Cellular response to chemical stress R-HSA-9711123 7.188378e-01 0.143 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 7.253594e-01 0.139 0 0
Biosynthesis of maresins R-HSA-9018682 7.266710e-01 0.139 0 0
Mitochondrial mRNA modification R-HSA-9937008 7.266710e-01 0.139 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 7.296363e-01 0.137 0 0
NGF-stimulated transcription R-HSA-9031628 7.296692e-01 0.137 0 0
Metal ion SLC transporters R-HSA-425410 7.296692e-01 0.137 0 0
RUNX2 regulates bone development R-HSA-8941326 7.327597e-01 0.135 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 7.352430e-01 0.134 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 7.352430e-01 0.134 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 7.352430e-01 0.134 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 7.352430e-01 0.134 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 7.352430e-01 0.134 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 7.352430e-01 0.134 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 7.352430e-01 0.134 0 0
Sodium/Calcium exchangers R-HSA-425561 7.352430e-01 0.134 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 7.352430e-01 0.134 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.365247e-01 0.133 0 0
NCAM signaling for neurite out-growth R-HSA-375165 7.412769e-01 0.130 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 7.412769e-01 0.130 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 7.420965e-01 0.130 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 7.420965e-01 0.130 0 0
Deadenylation of mRNA R-HSA-429947 7.436531e-01 0.129 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 7.436531e-01 0.129 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.436531e-01 0.129 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 7.467228e-01 0.127 0 0
Signaling by FGFR2 in disease R-HSA-5655253 7.540846e-01 0.123 0 0
PI3K Cascade R-HSA-109704 7.540846e-01 0.123 0 0
FOXO-mediated transcription R-HSA-9614085 7.564545e-01 0.121 0 0
MET activates RAS signaling R-HSA-8851805 7.577011e-01 0.121 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 7.577011e-01 0.121 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 7.577011e-01 0.121 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 7.577011e-01 0.121 0 0
GRB2 events in EGFR signaling R-HSA-179812 7.577011e-01 0.121 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 7.577011e-01 0.121 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 7.577011e-01 0.121 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 7.577011e-01 0.121 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 7.577011e-01 0.121 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 7.577011e-01 0.121 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 7.577011e-01 0.121 0 0
OAS antiviral response R-HSA-8983711 7.577011e-01 0.121 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 7.597223e-01 0.119 0 0
Laminin interactions R-HSA-3000157 7.597223e-01 0.119 0 0
HDMs demethylate histones R-HSA-3214842 7.597223e-01 0.119 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 7.597223e-01 0.119 0 0
Interleukin-7 signaling R-HSA-1266695 7.597223e-01 0.119 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 7.600963e-01 0.119 0 0
Elastic fibre formation R-HSA-1566948 7.600963e-01 0.119 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 7.600963e-01 0.119 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 7.656385e-01 0.116 0 0
FCERI mediated NF-kB activation R-HSA-2871837 7.693746e-01 0.114 1 1
Nuclear Receptor transcription pathway R-HSA-383280 7.717138e-01 0.113 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 7.728920e-01 0.112 0 0
Cellular response to hypoxia R-HSA-1234174 7.729669e-01 0.112 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 7.732556e-01 0.112 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 7.782554e-01 0.109 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 7.782554e-01 0.109 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 7.782554e-01 0.109 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 7.782554e-01 0.109 0 0
Diseases of nucleotide metabolism R-HSA-9735804 7.782554e-01 0.109 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 7.782554e-01 0.109 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 7.782554e-01 0.109 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 7.782554e-01 0.109 0 0
Interleukin-2 family signaling R-HSA-451927 7.851230e-01 0.105 0 0
Amino acids regulate mTORC1 R-HSA-9639288 7.874679e-01 0.104 0 0
Regulation of PTEN stability and activity R-HSA-8948751 7.874679e-01 0.104 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.892538e-01 0.103 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.892538e-01 0.103 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.892538e-01 0.103 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 7.897975e-01 0.102 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 7.968034e-01 0.099 0 0
Maturation of spike protein R-HSA-9694548 7.968034e-01 0.099 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 7.970672e-01 0.099 0 0
cGMP effects R-HSA-418457 7.970672e-01 0.099 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 7.970672e-01 0.099 0 0
CRMPs in Sema3A signaling R-HSA-399956 7.970672e-01 0.099 0 0
Hydrolysis of LPC R-HSA-1483115 7.970672e-01 0.099 0 0
Formation of the active cofactor, UDP-glucuronate R-HSA-173599 7.970672e-01 0.099 0 0
Physiological factors R-HSA-5578768 7.970672e-01 0.099 0 0
Prolactin receptor signaling R-HSA-1170546 7.970672e-01 0.099 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 7.970672e-01 0.099 0 0
Acyl chain remodeling of CL R-HSA-1482798 7.970672e-01 0.099 0 0
Zinc transporters R-HSA-435354 7.970672e-01 0.099 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 7.970672e-01 0.099 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 8.027841e-01 0.095 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.049088e-01 0.094 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 8.079479e-01 0.093 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 8.142841e-01 0.089 0 0
SHC1 events in EGFR signaling R-HSA-180336 8.142841e-01 0.089 0 0
G beta:gamma signalling through BTK R-HSA-8964315 8.142841e-01 0.089 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 8.142841e-01 0.089 0 0
Telomere C-strand synthesis initiation R-HSA-174430 8.142841e-01 0.089 0 0
p38MAPK events R-HSA-171007 8.142841e-01 0.089 0 0
Transport and metabolism of PAPS R-HSA-174362 8.142841e-01 0.089 0 0
Biotin transport and metabolism R-HSA-196780 8.142841e-01 0.089 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 8.142841e-01 0.089 0 0
Other semaphorin interactions R-HSA-416700 8.142841e-01 0.089 0 0
Signaling by Activin R-HSA-1502540 8.142841e-01 0.089 0 0
DNA Damage Reversal R-HSA-73942 8.142841e-01 0.089 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 8.148401e-01 0.089 1 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.185720e-01 0.087 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.185720e-01 0.087 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.202284e-01 0.086 0 0
IRS-mediated signalling R-HSA-112399 8.262262e-01 0.083 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 8.275459e-01 0.082 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 8.275459e-01 0.082 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.275459e-01 0.082 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 8.275459e-01 0.082 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 8.300412e-01 0.081 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 8.300412e-01 0.081 0 0
Killing mechanisms R-HSA-9664420 8.300412e-01 0.081 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 8.300412e-01 0.081 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 8.300412e-01 0.081 0 0
Atorvastatin ADME R-HSA-9754706 8.300412e-01 0.081 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 8.300412e-01 0.081 0 0
Differentiation of T cells R-HSA-9945266 8.300412e-01 0.081 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 8.300412e-01 0.081 0 0
Mitochondrial Uncoupling R-HSA-166187 8.300412e-01 0.081 0 0
Attachment and Entry R-HSA-9678110 8.300412e-01 0.081 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 8.309705e-01 0.080 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 8.352442e-01 0.078 0 0
Cardiac conduction R-HSA-5576891 8.365548e-01 0.078 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 8.428857e-01 0.074 0 0
Amino acid transport across the plasma membrane R-HSA-352230 8.432968e-01 0.074 0 0
Regulation of beta-cell development R-HSA-186712 8.432968e-01 0.074 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 8.444623e-01 0.073 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 8.444623e-01 0.073 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 8.444623e-01 0.073 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 8.444623e-01 0.073 0 0
Phase 2 - plateau phase R-HSA-5576893 8.444623e-01 0.073 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 8.444623e-01 0.073 0 0
Fibronectin matrix formation R-HSA-1566977 8.444623e-01 0.073 0 0
Synthesis of PG R-HSA-1483148 8.444623e-01 0.073 0 0
Galactose catabolism R-HSA-70370 8.444623e-01 0.073 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 8.444623e-01 0.073 0 0
RAB geranylgeranylation R-HSA-8873719 8.512890e-01 0.070 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 8.512890e-01 0.070 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 8.515696e-01 0.070 0 0
tRNA processing R-HSA-72306 8.527237e-01 0.069 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 8.576605e-01 0.067 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 8.576605e-01 0.067 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 8.576605e-01 0.067 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 8.576605e-01 0.067 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 8.576605e-01 0.067 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 8.576605e-01 0.067 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.576605e-01 0.067 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 8.589330e-01 0.066 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 8.589330e-01 0.066 0 0
Nuclear RNA decay R-HSA-9930044 8.594551e-01 0.066 0 0
Asparagine N-linked glycosylation R-HSA-446203 8.634198e-01 0.064 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 8.644568e-01 0.063 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.688289e-01 0.061 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 8.697395e-01 0.061 0 0
PKA activation in glucagon signalling R-HSA-164378 8.697395e-01 0.061 0 0
Synaptic adhesion-like molecules R-HSA-8849932 8.697395e-01 0.061 0 0
Tie2 Signaling R-HSA-210993 8.697395e-01 0.061 0 0
GPER1 signaling R-HSA-9634597 8.723031e-01 0.059 0 0
Integrin cell surface interactions R-HSA-216083 8.768188e-01 0.057 0 0
ABC transporter disorders R-HSA-5619084 8.768188e-01 0.057 0 0
eNOS activation R-HSA-203615 8.776248e-01 0.057 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 8.776248e-01 0.057 0 0
Signal amplification R-HSA-392518 8.776248e-01 0.057 0 0
IGF1R signaling cascade R-HSA-2428924 8.798800e-01 0.056 0 0
Insulin receptor signalling cascade R-HSA-74751 8.798800e-01 0.056 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 8.807942e-01 0.055 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 8.807942e-01 0.055 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.858732e-01 0.053 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 8.862361e-01 0.052 0 0
Extracellular matrix organization R-HSA-1474244 8.866533e-01 0.052 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 8.909112e-01 0.050 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 8.909112e-01 0.050 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 8.909112e-01 0.050 0 0
Acyl chain remodelling of PI R-HSA-1482922 8.909112e-01 0.050 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 8.909112e-01 0.050 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.920747e-01 0.050 0 0
Mitochondrial biogenesis R-HSA-1592230 8.925075e-01 0.049 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 8.936037e-01 0.049 0 0
G1/S-Specific Transcription R-HSA-69205 8.936037e-01 0.049 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.936037e-01 0.049 0 0
SLC-mediated transport of amino acids R-HSA-9958863 8.980721e-01 0.047 0 0
Kidney development R-HSA-9830369 8.980721e-01 0.047 0 0
G-protein activation R-HSA-202040 9.001702e-01 0.046 0 0
Signalling to RAS R-HSA-167044 9.001702e-01 0.046 0 0
ERK/MAPK targets R-HSA-198753 9.001702e-01 0.046 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 9.001702e-01 0.046 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 9.001702e-01 0.046 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.001702e-01 0.046 0 0
Neddylation R-HSA-8951664 9.034809e-01 0.044 0 0
Purine salvage R-HSA-74217 9.076237e-01 0.042 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 9.086439e-01 0.042 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 9.086439e-01 0.042 0 0
G alpha (q) signalling events R-HSA-416476 9.144980e-01 0.039 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 9.163987e-01 0.038 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 9.163987e-01 0.038 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 9.163987e-01 0.038 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 9.163987e-01 0.038 0 0
Hedgehog 'on' state R-HSA-5632684 9.185299e-01 0.037 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.198993e-01 0.036 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 9.234957e-01 0.035 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.234957e-01 0.035 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 9.234957e-01 0.035 0 0
Interleukin receptor SHC signaling R-HSA-912526 9.234957e-01 0.035 0 0
Formation of the ureteric bud R-HSA-9830674 9.234957e-01 0.035 0 0
Interleukin-20 family signaling R-HSA-8854691 9.234957e-01 0.035 0 0
Gastrulation R-HSA-9758941 9.240613e-01 0.034 0 0
CYP2E1 reactions R-HSA-211999 9.299906e-01 0.032 0 0
Complex III assembly R-HSA-9865881 9.299906e-01 0.032 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 9.299906e-01 0.032 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.299906e-01 0.032 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.305408e-01 0.031 0 0
Intra-Golgi traffic R-HSA-6811438 9.306268e-01 0.031 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.306268e-01 0.031 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.306268e-01 0.031 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.311184e-01 0.031 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.311184e-01 0.031 0 0
PI Metabolism R-HSA-1483255 9.338300e-01 0.030 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.352313e-01 0.029 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 9.359345e-01 0.029 0 0
Hyaluronan degradation R-HSA-2160916 9.359345e-01 0.029 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 9.359345e-01 0.029 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.359345e-01 0.029 0 0
Formation of the nephric duct R-HSA-9830364 9.359345e-01 0.029 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.379311e-01 0.028 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 9.413740e-01 0.026 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 9.413740e-01 0.026 0 0
Urea cycle R-HSA-70635 9.413740e-01 0.026 0 0
Sphingolipid catabolism R-HSA-9845614 9.413740e-01 0.026 0 0
Aquaporin-mediated transport R-HSA-445717 9.431399e-01 0.025 0 0
Surfactant metabolism R-HSA-5683826 9.442019e-01 0.025 0 0
Proteasome assembly R-HSA-9907900 9.442019e-01 0.025 0 0
Cristae formation R-HSA-8949613 9.463520e-01 0.024 0 0
Triglyceride biosynthesis R-HSA-75109 9.463520e-01 0.024 0 0
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane R-HSA-83936 9.463520e-01 0.024 0 0
Synthesis of PE R-HSA-1483213 9.463520e-01 0.024 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.463520e-01 0.024 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.481357e-01 0.023 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 9.481357e-01 0.023 0 0
Telomere Extension By Telomerase R-HSA-171319 9.509076e-01 0.022 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 9.509076e-01 0.022 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 9.509076e-01 0.022 0 0
Pyrimidine salvage R-HSA-73614 9.509076e-01 0.022 0 0
Prednisone ADME R-HSA-9757110 9.509076e-01 0.022 0 0
Collagen formation R-HSA-1474290 9.522170e-01 0.021 0 0
Xenobiotics R-HSA-211981 9.531891e-01 0.021 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.536661e-01 0.021 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.550766e-01 0.020 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.588917e-01 0.018 0 0
Neurotransmitter clearance R-HSA-112311 9.588917e-01 0.018 0 0
Formation of the cornified envelope R-HSA-6809371 9.601049e-01 0.018 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.613790e-01 0.017 0 0
Aspartate and asparagine metabolism R-HSA-8963693 9.623831e-01 0.017 0 0
Regulation of insulin secretion R-HSA-422356 9.638885e-01 0.016 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.640208e-01 0.016 0 0
Azathioprine ADME R-HSA-9748787 9.641436e-01 0.016 0 0
HS-GAG degradation R-HSA-2024096 9.655782e-01 0.015 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.683724e-01 0.014 0 0
Cardiogenesis R-HSA-9733709 9.685020e-01 0.014 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.685020e-01 0.014 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 9.691130e-01 0.014 0 0
ECM proteoglycans R-HSA-3000178 9.705451e-01 0.013 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 9.711776e-01 0.013 0 0
Miscellaneous transport and binding events R-HSA-5223345 9.711776e-01 0.013 0 0
Glutamate and glutamine metabolism R-HSA-8964539 9.711776e-01 0.013 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.714035e-01 0.013 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.724588e-01 0.012 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.736261e-01 0.012 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 9.736261e-01 0.012 0 0
Hyaluronan metabolism R-HSA-2142845 9.736261e-01 0.012 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 9.736261e-01 0.012 0 0
Peptide hormone metabolism R-HSA-2980736 9.743657e-01 0.011 0 0
Paracetamol ADME R-HSA-9753281 9.753431e-01 0.011 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.758668e-01 0.011 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.771356e-01 0.010 0 0
HS-GAG biosynthesis R-HSA-2022928 9.779172e-01 0.010 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.779172e-01 0.010 0 0
Triglyceride catabolism R-HSA-163560 9.779172e-01 0.010 0 0
Dectin-2 family R-HSA-5621480 9.788016e-01 0.009 0 0
Signaling by Insulin receptor R-HSA-74752 9.795368e-01 0.009 0 0
Voltage gated Potassium channels R-HSA-1296072 9.797935e-01 0.009 0 0
NCAM1 interactions R-HSA-419037 9.797935e-01 0.009 0 0
Metabolism of folate and pterines R-HSA-196757 9.797935e-01 0.009 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.803838e-01 0.009 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.811722e-01 0.008 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 9.815105e-01 0.008 0 0
Triglyceride metabolism R-HSA-8979227 9.817879e-01 0.008 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.817879e-01 0.008 0 0
Mitochondrial protein degradation R-HSA-9837999 9.819679e-01 0.008 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.830816e-01 0.007 0 0
Nucleotide salvage R-HSA-8956321 9.843641e-01 0.007 0 0
Tryptophan catabolism R-HSA-71240 9.845194e-01 0.007 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.849750e-01 0.007 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.858350e-01 0.006 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.865845e-01 0.006 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.870358e-01 0.006 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.878043e-01 0.005 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.878043e-01 0.005 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.909152e-01 0.004 0 0
Somitogenesis R-HSA-9824272 9.909152e-01 0.004 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.909152e-01 0.004 0 0
COPII-mediated vesicle transport R-HSA-204005 9.921876e-01 0.003 0 0
Synthesis of PC R-HSA-1483191 9.923943e-01 0.003 0 0
Neurotransmitter release cycle R-HSA-112310 9.926150e-01 0.003 0 0
Integration of energy metabolism R-HSA-163685 9.927200e-01 0.003 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.927723e-01 0.003 0 0
Metabolism of cofactors R-HSA-8978934 9.927723e-01 0.003 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.930410e-01 0.003 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.936327e-01 0.003 0 0
Aspirin ADME R-HSA-9749641 9.938160e-01 0.003 0 0
PPARA activates gene expression R-HSA-1989781 9.939747e-01 0.003 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.941742e-01 0.003 0 0
FCGR activation R-HSA-2029481 9.944488e-01 0.002 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.946294e-01 0.002 0 0
Cytosolic sulfonation of small molecules R-HSA-156584 9.946696e-01 0.002 0 0
Interleukin-10 signaling R-HSA-6783783 9.958215e-01 0.002 0 0
Glucuronidation R-HSA-156588 9.959173e-01 0.002 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.961379e-01 0.002 0 0
Visual phototransduction R-HSA-2187338 9.964720e-01 0.002 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.966388e-01 0.001 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.967018e-01 0.001 0 0
Synthesis of PA R-HSA-1483166 9.968731e-01 0.001 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.973826e-01 0.001 0 0
GPCR downstream signalling R-HSA-388396 9.975239e-01 0.001 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.976053e-01 0.001 0 0
G alpha (s) signalling events R-HSA-418555 9.977791e-01 0.001 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.978090e-01 0.001 0 0
Endogenous sterols R-HSA-211976 9.978090e-01 0.001 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.983222e-01 0.001 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.985956e-01 0.001 0 0
Antimicrobial peptides R-HSA-6803157 9.987125e-01 0.001 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.987142e-01 0.001 0 0
Nicotinate metabolism R-HSA-196807 9.987152e-01 0.001 0 0
O-linked glycosylation of mucins R-HSA-913709 9.988246e-01 0.001 0 0
Bacterial Infection Pathways R-HSA-9824439 9.989593e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.990162e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.990497e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.990999e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.991111e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.992167e-01 0.000 0 0
Potassium Channels R-HSA-1296071 9.992167e-01 0.000 0 0
Transport of vitamins, nucleosides, and related molecules R-HSA-425397 9.993109e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.993852e-01 0.000 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.995584e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.996090e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.996305e-01 0.000 0 0
Keratinization R-HSA-6805567 9.997647e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.997682e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.997834e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.998612e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999011e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.999185e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999587e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999694e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999740e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999796e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999835e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999887e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.999892e-01 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.999908e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999949e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999957e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999983e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.999988e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999989e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999989e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999995e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999995e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999996e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999996e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Metabolism of steroids R-HSA-8957322 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways