GCK

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A1L429 S7 Sugiyama GAGE12B; GAGE12C; GAGE12D; GAGE12E ______________MSWRGRsTyyWPRPRRYVQPPEMIGPM
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A6NDE8 S7 Sugiyama GAGE12H ______________MSWRGRsTyyWPRPRRYVQPPEMIGPM
A6NER3 S7 Sugiyama GAGE12J ______________MSWRGRsTyyWPRPRPYVQPPEMIGPM
B2RPK0 S15 Sugiyama HMGB1P1 HMG1L1 HMGB1L1 ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHSDAS
B2RPK0 T22 Sugiyama HMGB1P1 HMG1L1 HMGB1L1 GKGDPKKPRGKMssyAFFVQtCREEHKKKHSDASVNFSEFS
O00571 T156 Sugiyama DDX3X DBX DDX3 WSKPLPPSERLEQELFsGGNtGINFEKYDDIPVEATGNNCP
O14556 T301 Sugiyama GAPDHS GAPD2 GAPDH2 GAPDS HSD-35 HSD35 ASTGAAKAVTKVIPELKGKLtGMAFRVPTPDVSVVDLTCRL
O14818 T152 Sugiyama PSMA7 HSPC LIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFL
O14818 Y145 Sugiyama PSMA7 HSPC RPFGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGA
O15212 T107 Sugiyama PFDN6 HKE2 PFD6 IKRYESQLRDLERQsEQQREtLAQLQQEFQRAQAAKAGAPG
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O15523 T154 Sugiyama DDX3Y DBY WSKPLPPSERLEQELFsGGNtGINFEKYDDIPVEATGSNCP
O43390 T137 Sugiyama HNRNPR HNRPR ESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43852 T196 Sugiyama CALU FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD
O60361 T88 Sugiyama NME2P1 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
O60506 T134 Sugiyama SYNCRIP HNRPQ NSAP1 DSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O75821 T190 Sugiyama EIF3G EIF3S4 PYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNKt
O75821 T240 Sugiyama EIF3G EIF3S4 DGAsRRGESMQPNRRADDNAtIRVtNLSEDTRETDLQELFR
O76087 S7 Sugiyama GAGE7 GAGE12I GAGE7B ______________MSWRGRsTyyWPRPRRYVQPPEMIGPM
O94776 S433 Sugiyama MTA2 MTA1L1 PID ATRGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQt
O94776 S496 Sugiyama MTA2 MTA1L1 PID RRAARRPYAPINANAIKAECsIRLPKAAKTPLKIHPLVRLP
O95071 T119 Sugiyama UBR5 EDD EDD1 HYD KIAA0896 GRTSRPGRTSDsPWFLsGSEtLGRLAGNTLGSRWSsGVGGs
O95218 S181 Sugiyama ZRANB2 ZIS ZNF265 DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR
O95835 T1079 PSP LATS1 WARTS DtLNGWYKNGKHPEHAFYEFtFRRFFDDNGYPYNYPKPIEY
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00558 S399 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 T376 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG
P00558 T378 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA
P00558 T394 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL
P00966 T210 Sugiyama ASS1 ASS yEAGILENPKNQAPPGLytKtQDPAKAPNtPDILEIEFKKG
P02810 S24 ELM|iPTMNet|EPSD|PSP PRH1; PRH2 ILLSVALLAFSSAQDLDEDVsQEDVPLVISDGGDsEQFIDE
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04083 T132 Sugiyama ANXA1 ANX1 LPC1 LKTPAQFDADELRAAMKGLGtDEDtLIEILAsRtNKEIRDI
P04083 T145 Sugiyama ANXA1 ANX1 LPC1 AAMKGLGtDEDtLIEILAsRtNKEIRDINRVYREELKRDLA
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T229 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 AstGAAKAVGKVIPELNGKLtGMAFRVPtANVsVVDLtCRL
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04792 S187 Sugiyama HSPB1 HSP27 HSP28 APMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAAK__
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05187 T185 Sugiyama ALPP PLAP VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05455 T302 Sugiyama SSB ALGKAKDANNGNLQLRNKEVtWEVLEGEVEKEALKKIIEDQ
P06733 S272 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI
P06733 S37 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733 S40 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 T55 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06748 S137 Sugiyama NPM1 NPM VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 T276 Sugiyama LDHB SVADLIESMLKNLSRIHPVStMVKGMYGIENEVFLSLPCIL
P07195 T302 Sugiyama LDHB YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD
P07205 S399 Sugiyama PGK2 PGKB CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205 T394 Sugiyama PGK2 PGKB GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07437 T72 Sugiyama TUBB TUBB5 OK/SW-cl.56 NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
P07737 S85 Sugiyama PFN1 tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK
P07814 S739 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV
P07814 T1506 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 LCELQPGAKCVCGKNPAKyytLFGRsy______________
P07814 T745 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAVQGDVVR
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07900 T171 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILHLK
P07900 T467 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKEN
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 T166 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILHLK
P08238 T616 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE
P08708 T102 Sugiyama RPS17 RPS17L DNyVPEVsALDQEIIEVDPDtKEMLKLLDFGsLsNLQVtQP
P08708 T22 Sugiyama RPS17 RPS17L GRVRTKTVKKAARVIIEKyytRLGNDFHtNKRVCEEIAIIP
P08708 T30 Sugiyama RPS17 RPS17L KKAARVIIEKyytRLGNDFHtNKRVCEEIAIIPSKKLRNKI
P09104 S37 Sugiyama ENO2 NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09104 S40 Sugiyama ENO2 VEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGK
P09211 T62 Sugiyama GSTP1 FAEES3 GST3 GsLKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGK
P09211 T68 Sugiyama GSTP1 FAEES3 GST3 CLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQEAA
P09211 Y64 Sugiyama GSTP1 FAEES3 GST3 LKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQ
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09429 S15 Sugiyama HMGB1 HMG1 ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHPDAs
P09429 T22 Sugiyama HMGB1 HMG1 GKGDPKKPRGKMssyAFFVQtCREEHKKKHPDAsVNFsEFs
P09651 S368 Sugiyama HNRNPA1 HNRPA1 FAKPRNQGGyGGssssssyGsGRRF________________
P09661 S212 Sugiyama SNRPA1 KKGGPsPGDVEAIKNAIANAstLAEVERLKGLLQsGQIPGR
P09923 T182 Sugiyama ALPI VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC
P0CL80 S7 Sugiyama GAGE12F ______________MSWRGRsTyyWPRPRRYVQPPEMIGPM
P0DPH7 T51 Sugiyama TUBA3C TUBA2 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P0DSO3 S7 Sugiyama GAGE4 ______________MSWRGRsTyyWPRPRRYVQPPEMIGPM
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10412 S58 Sugiyama H1-4 H1F4 HIST1H1E PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P10412 T92 Sugiyama H1-4 H1F4 HIST1H1E DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P10412 T96 Sugiyama H1-4 H1F4 HIST1H1E NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T64 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11940 T379 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 AtKPLyVALAQRKEERQAHLtNQyMQRMASVRAVPNPVINP
P13489 T176 Sugiyama RNH1 PRI RNH AASCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKD
P13639 T484 Sugiyama EEF2 EF2 VPCGNIVGLVGVDQFLVKtGtIttFEHAHNMRVMKFsVsPV
P13639 T5 Sugiyama EEF2 EF2 ________________MVNFtVDQIRAIMDKKANIRNMsVI
P13929 S37 Sugiyama ENO3 NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P13929 S40 Sugiyama ENO3 VEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGK
P13929 T19 Sugiyama ENO3 __MAMQKIFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGA
P13929 T26 Sugiyama ENO3 IFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGAstGIyEA
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S77 Sugiyama PKM OIP3 PK2 PK3 PKM2 sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs
P14618 T45 Sugiyama PKM OIP3 PK2 PK3 PKM2 TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14618 T80 Sugiyama PKM OIP3 PK2 PK3 PKM2 tLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAs
P14618 T87 Sugiyama PKM OIP3 PK2 PK3 PKM2 sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P15259 S189 Sugiyama PGAM2 PGAMM EEIVPQIKAGKRVLIAAHGNsLRGIVKHLEGMSDQAIMELN
P15311 T533 Sugiyama EZR VIL2 NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII
P15531 T103 Sugiyama NME1 NDPKA NM23 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P15880 T202 Sugiyama RPS2 RPS4 CKVTGRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDC
P15880 T224 Sugiyama RPS2 RPS4 IVsAPVPKKLLMMAGIDDCytsARGCtAtLGNFAKATFDAI
P15880 T232 Sugiyama RPS2 RPS4 KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P15924 T61 Sugiyama DSP YYSRRGVITDQNsDGyCQtGtMsRHQNQNTIQELLQNCSDC
P16083 T59 Sugiyama NQO2 NMOR2 VSDLyAMNLEPRATDKDITGtLSNPEVFNyGVEtHEAyKQR
P16401 T95 Sugiyama H1-5 H1F5 HIST1H1B DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16401 T99 Sugiyama H1-5 H1F5 HIST1H1B NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16402 S59 Sugiyama H1-3 H1F3 HIST1H1D PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P16402 T93 Sugiyama H1-3 H1F3 HIST1H1D DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16402 T97 Sugiyama H1-3 H1F3 HIST1H1D NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAASGEG
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S58 Sugiyama H1-2 H1F2 HIST1H1C PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P16403 T92 Sugiyama H1-2 H1F2 HIST1H1C DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16403 T96 Sugiyama H1-2 H1F2 HIST1H1C NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17844 S520 Sugiyama DDX5 G17P1 HELR HLR1 GKRGGFNTFRDRENYDRGYssLLKRDFGAKTQNGVYSAANY
P17987 S544 Sugiyama TCP1 CCT1 CCTA ILRIDDLIKLHPESKDDKHGsyEDAVHsGALND________
P18124 T17 Sugiyama RPL7 ____MEGVEEKKKEVPAVPEtLKKKRRNFAELKIKRLRKKF
P18206 T1118 Sugiyama VCL LMQsVKETVREAEAAsIKIRtDAGFtLRWVRKTPWyQ____
P18206 T1123 Sugiyama VCL KETVREAEAAsIKIRtDAGFtLRWVRKTPWyQ_________
P18621 S14 Sugiyama RPL17 _______MVRysLDPENPtKsCKSRGSNLRVHFKNtRETAQ
P18621 T12 Sugiyama RPL17 _________MVRysLDPENPtKsCKSRGSNLRVHFKNtRET
P18621 T79 Sugiyama RPL17 PFRRYNGGVGRCAQAKQWGWtQGRWPKKSAEFLLHMLKNAE
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 S189 Sugiyama PGAM1 PGAMA CDABP0006 EEIVPQIKEGKRVLIAAHGNsLRGIVKHLEGLSEEAIMELN
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 S619 Sugiyama NCL RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK
P19338 Y462 Sugiyama NCL AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs
P20042 S67 Sugiyama EIF2S2 EIF2B EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK
P20042 T163 Sugiyama EIF2S2 EIF2B DEALEDEDNKKDDGIsFsNQtGPAWAGSERDytyEELLNRV
P20674 T105 Sugiyama COX5A EPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYPY
P21291 T79 Sugiyama CSRP1 CSRP CYRP KSCyGKKYGPKGyGyGQGAGtLstDKGEsLGIKHEEAPGHR
P22090 S204 Sugiyama RPS4Y1 RPS4Y PRO2646 IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN
P22314 T600 Sugiyama UBA1 A1S9T UBE1 ARMYMDRRCVYYRKPLLESGtLGtKGNVQVVIPFLTESySS
P22392 T103 Sugiyama NME2 NM23B VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23381 S358 Sugiyama WARS1 IFI53 WARS WRS TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23381 T364 Sugiyama WARS1 IFI53 WARS WRS QGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFsGGRDtI
P23381 T383 Sugiyama WARS1 IFI53 WARS WRS DtAKQIKTKVNKHAFsGGRDtIEEHRQFGGNCDVDVSFMYL
P23396 S35 Sugiyama RPS3 OK/SW-cl.26 GIFKAELNEFLtRELAEDGysGVEVRVtPTRTEIIILATRT
P23396 T242 Sugiyama RPS3 OK/SW-cl.26 PIsEQKGGKPEPPAMPQPVPtA___________________
P23396 T26 Sugiyama RPS3 OK/SW-cl.26 sKKRKFVADGIFKAELNEFLtRELAEDGysGVEVRVtPTRT
P23396 T70 Sugiyama RPS3 OK/SW-cl.26 ILATRTQNVLGEKGRRIRELtAVVQKRFGFPEGsVELyAEK
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23921 T555 Sugiyama RRM1 RR1 IyyGALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTP
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26038 T526 Sugiyama MSN EERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHA
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26373 T24 Sugiyama RPL13 BBC1 OK/SW-cl.46 SRNGMVLKPHFHKDWQRRVAtWFNQPARKIRRRKARQAKAR
P26583 S15 Sugiyama HMGB2 HMG2 ______MGKGDPNKPRGKMssyAFFVQtCREEHKKKHPDss
P26583 T22 Sugiyama HMGB2 HMG2 GKGDPNKPRGKMssyAFFVQtCREEHKKKHPDssVNFAEFS
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P29401 T346 Sugiyama TKT AKLGHAsDRIIALDGDtKNstFsEIFKKEHPDRFIECYIAE
P29401 T444 Sugiyama TKT DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT
P29401 T454 Sugiyama TKT LAMFRsVPtstVFyPsDGVAtEKAVELAANTKGICFIRTsR
P29692 T73 Sugiyama EEF1D EF1D ARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVENQs
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050 T135 Sugiyama RPL12 QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI
P30050 T18 Sugiyama RPL12 ___MPPKFDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLs
P30050 T25 Sugiyama RPL12 FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD
P31947 T207 Sugiyama SFN HME1 PEEAISLAKTtFDEAMADLHtLsEDsyKDstLIMQLLRDNL
P31948 T145 Sugiyama STIP1 MNPFNMPNLYQKLESDPRtRtLLSDPTYRELIEQLRNKPSD
P31948 T243 Sugiyama STIP1 KQALKEKELGNDAYKKKDFDtALKHYDKAKELDPtNMtyIT
P31949 T33 Sugiyama S100A11 MLN70 S100C CIESLIAVFQKYAGKDGyNytLsKtEFLsFMNTELAAFTKN
P32969 T85 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 KELATVRTICSHVQNMIKGVtLGFRYKMRSVYAHFPINVVI
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P35268 T62 Sugiyama RPL22 FLQERIKVNGKAGNLGGGVVtIERsKSKITVTSEVPFSKRY
P36578 S63 Sugiyama RPL4 RPL1 NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG
P36578 S66 Sugiyama RPL4 RPL1 KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T266 Sugiyama RPL4 RPL1 VGRFCIWtEsAFRKLDELyGtWRKAAsLKsNyNLPMHKMIN
P36578 T287 Sugiyama RPL4 RPL1 WRKAAsLKsNyNLPMHKMINtDLsRILKsPEIQRALRAPRK
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578 T69 Sugiyama RPL4 RPL1 RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P37108 T45 Sugiyama SRP14 sVyItLKKYDGRTKPIPKKGtVEGFEPADNKCLLRATDGKK
P37802 S145 Sugiyama TAGLN2 KIAA0120 CDABP0035 VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P37802 Y192 Sugiyama TAGLN2 KIAA0120 CDABP0035 NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________
P38646 T111 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VAFtADGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDP
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39019 S59 Sugiyama RPS19 LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY
P39019 T55 Sugiyama RPS19 DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM
P39019 T60 Sugiyama RPS19 AKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIYG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P40429 T155 Sugiyama RPL13A FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P40939 T117 Sugiyama HADHA HADH CFIAGADINMLAACKTLQEVtQLSQEAQRIVEKLEKSTKPI
P41091 T22 Sugiyama EIF2S3 EIF2G AGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAtI
P41091 T41 Sugiyama EIF2S3 EIF2G ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
P41091 T46 Sugiyama EIF2S3 EIF2G tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHt
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P42766 T59 Sugiyama RPL35 GAASKLsKIRVVRKSIARVLtVINQtQKENLRKFYKGKKyK
P42766 T64 Sugiyama RPL35 LsKIRVVRKSIARVLtVINQtQKENLRKFYKGKKyKPLDLR
P42858 T3 PSP HTT HD IT15 __________________MAtLEKLMKAFEsLKsFQQQQQQ
P46776 T80 Sugiyama RPL27A HYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAKNKtGAAPI
P46776 T86 Sugiyama RPL27A NQsFCPtVNLDKLWtLVsEQtRVNAAKNKtGAAPIIDVVRs
P46776 Y52 Sugiyama RPL27A RGNAGGLHHHRINFDKyHPGyFGKVGMKHYHLKRNQsFCPt
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46777 S230 Sugiyama RPL5 MSTP030 yLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAHAAIREN
P46778 T124 Sugiyama RPL21 sFLKRVKENDQKKKEAKEKGtWVQLKRQPAPPREAHFVRTN
P46778 T29 Sugiyama RPL21 RGTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQ
P46779 T80 Sugiyama RPL28 VVVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKN
P46779 T81 Sugiyama RPL28 VVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKNK
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46783 T148 Sugiyama RPS10 RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P46940 T1471 Sugiyama IQGAP1 KIAA0051 tLQEKKEKIQTGLKKLTELGtVDPKNKyQELINDIARDIRN
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P47756 T186 Sugiyama CAPZB HYKLTSTVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDC
P48426 S115 Sugiyama PIP4K2A PI5P4KA PIP5K2 PIP5K2A PMVFRNLRERFGIDDQDFQNsLTRSAPLPNDSQARSGARFH
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P49368 T430 Sugiyama CCT3 CCTG TRIC5 GGGASEMAVAHALTEKSKAMtGVEQWPyRAVAQALEVIPRT
P49368 T459 Sugiyama CCT3 CCTG TRIC5 AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG
P49368 T486 Sugiyama CCT3 CCTG TRIC5 LRAKHtQENCEtWGVNGEtGtLVDMKELGIWEPLAVKLQTY
P49589 S34 Sugiyama CARS1 CARS VQPQWsPPAGtQPCRLHLyNsLtRNKEVFIPQDGKKVTWYC
P49773 T17 Sugiyama HINT1 HINT PKCI1 PRKCNH1 ____MADEIAKAQVARPGGDtIFGKIIRKEIPAKIIFEDDR
P51149 T168 Sugiyama RAB7A RAB7 NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE
P51858 S83 Sugiyama HDGF HMG1L2 LFPyEEsKEKFGKPNKRKGFsEGLWEIENNPtVKASGYQSs
P51858 T94 Sugiyama HDGF HMG1L2 GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP
P51991 S375 Sugiyama HNRNPA3 HNRPA3 ssGsPyGGGyGsGGGsGGyGsRRF_________________
P53634 T431 Sugiyama CTSC CPPI GYGTDSASGMDYWIVKNsWGtGWGENGyFRIRRGtDECAIE
P53999 S56 Sugiyama SUB1 PC4 RPO2TC1 PVKKQKTGETsRALsssKQssssRDDNMFQIGKMRYVSVRD
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P55060 S931 Sugiyama CSE1L CAS XPO2 KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL
P55072 T761 Sugiyama VCP HEL-220 HEL-S-70 RFARRsVsDNDIRKyEMFAQtLQQsRGFGsFRFPsGNQGGA
P55209 S69 Sugiyama NAP1L1 NRP LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA
P55209 T64 Sugiyama NAP1L1 NRP QNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNL
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P60174 S204 Sugiyama TPI1 TPI EVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQ
P60174 S21 Sugiyama TPI1 TPI MAPSRKFFVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVV
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T205 Sugiyama TPI1 TPI VHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQP
P60174 T214 Sugiyama TPI1 TPI KsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGG
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T28 Sugiyama TPI1 TPI FVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVVCAPPtAy
P60174 T38 Sugiyama TPI1 TPI RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP
P60174 T46 Sugiyama TPI1 TPI IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN
P60174 Y209 Sugiyama TPI1 TPI LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660 Y86 Sugiyama MYL6 DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T203 Sugiyama ACTB RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T304 Sugiyama ACTB KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P60709 T318 Sugiyama ACTB VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60842 T80 Sugiyama EIF4A1 DDX2A EIF4A QRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDLKA
P60866 T6 Sugiyama RPS20 _______________MAFKDtGKtPVEPEVAIHRIRITLTS
P61163 T248 Sugiyama ACTR1A CTRN1 PQKDETLETEKAQyyLPDGstIEIGPSRFRAPELLFRPDLI
P61221 Y594 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 RPRINKLNsIKDVEQKKsGNyFFLDD_______________
P61247 S192 Sugiyama RPS3A FTE1 MFTL MTREVQTNDLKEVVNKLIPDsIGKDIEKACQsIyPLHDVFV
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61254 T93 Sugiyama RPL26 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
P61313 S97 Sugiyama RPL15 EC45 TCBAP0781 KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN
P61313 T80 Sugiyama RPL15 EC45 TCBAP0781 VIyRIRVRRGGRKRPVPKGAtyGKPVHHGVNQLKFARsLQs
P61353 S34 Sugiyama RPL27 LAGRYSGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVT
P61513 T16 Sugiyama RPL37A _____MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQHAK
P62081 T172 Sugiyama RPS7 RLIKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEF
P62241 S115 Sugiyama RPS8 OK/SW-cl.83 TLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEE
P62241 S160 Sugiyama RPS8 OK/SW-cl.83 KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62241 Y117 Sugiyama RPS8 OK/SW-cl.83 VKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEEIL
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62263 T140 Sugiyama RPS14 PRO2640 ARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL_________
P62266 S45 Sugiyama RPS23 KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62266 T34 Sugiyama RPS23 RSHRRDQKWHDKQYKKAHLGtALKANPFGGAsHAKGIVLEK
P62269 T60 Sugiyama RPS18 D6S218E YAHVVLRKADIDLTKRAGELtEDEVERVItIMQNPRQYKIP
P62269 T69 Sugiyama RPS18 D6S218E DIDLTKRAGELtEDEVERVItIMQNPRQYKIPDWFLNRQKD
P62273 S9 Sugiyama RPS29 ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T15 Sugiyama RPS11 ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR
P62280 T28 Sugiyama RPS11 RAyQKQPtIFQNKKRVLLGEtGKEKLPRYYKNIGLGFKtPK
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62314 T57 Sugiyama SNRPD1 NTHLKAVKMTLKNREPVQLEtLsIRGNNIRYFILPDsLPLD
P62316 T40 Sugiyama SNRPD2 SNRPD1 EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD
P62424 T142 Sugiyama RPL7A SURF-3 SURF3 AAGKGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVD
P62424 T144 Sugiyama RPL7A SURF-3 SURF3 GKGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVDPI
P62424 T84 Sugiyama RPL7A SURF-3 SURF3 QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP
P62701 S204 Sugiyama RPS4X CCG2 RPS4 SCAR tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN
P62701 T177 Sugiyama RPS4X CCG2 RPS4 SCAR NDtIQIDLEtGKITDFIKFDtGNLCMVtGGANLGRIGVITN
P62701 T184 Sugiyama RPS4X CCG2 RPS4 SCAR LEtGKITDFIKFDtGNLCMVtGGANLGRIGVITNRERHPGs
P62701 T247 Sugiyama RPS4X CCG2 RPS4 SCAR VIGKGNKPWIsLPRGKGIRLtIAEERDKRLAAKQSSG____
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T320 Sugiyama ACTA2 ACTSA ACTVS GIG46 VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62750 T126 Sugiyama RPL23A KHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAYVRLAPDyDA
P62753 S6 Sugiyama RPS6 OK/SW-cl.2 _______________MKLNIsFPAtGCQKLIEVDDERKLRt
P62753 T10 Sugiyama RPS6 OK/SW-cl.2 ___________MKLNIsFPAtGCQKLIEVDDERKLRtFyEK
P62753 T127 Sugiyama RPS6 OK/SW-cl.2 SVLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLFNL
P62753 T128 Sugiyama RPS6 OK/SW-cl.2 VLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLFNLs
P62753 T26 Sugiyama RPS6 OK/SW-cl.2 sFPAtGCQKLIEVDDERKLRtFyEKRMAtEVAADALGEEWK
P62826 T21 Sugiyama RAN ARA24 OK/SW-cl.81 MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA
P62826 T32 Sugiyama RAN ARA24 OK/SW-cl.81 KLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGVEVHPLVF
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62847 S78 Sugiyama RPS24 FGFRTHFGGGKttGFGMIyDsLDyAKKNEPKHRLARHGLYE
P62847 T69 Sugiyama RPS24 KTTPDVIFVFGFRTHFGGGKttGFGMIyDsLDyAKKNEPKH
P62851 T110 Sugiyama RPS25 ELLsKGLIKLVSKHRAQVIytRNtKGGDAPAAGEDA_____
P62851 T113 Sugiyama RPS25 sKGLIKLVSKHRAQVIytRNtKGGDAPAAGEDA________
P62857 T57 Sugiyama RPS28 DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________
P62888 S102 Sugiyama RPL30 GtACGKyyRVCtLAIIDPGDsDIIRsMPEQtGEK_______
P62888 T112 Sugiyama RPL30 CtLAIIDPGDsDIIRsMPEQtGEK_________________
P62888 T93 Sugiyama RPL30 HysGNNIELGtACGKyyRVCtLAIIDPGDsDIIRsMPEQtG
P62899 S15 Sugiyama RPL31 ______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG
P62899 T113 Sugiyama RPL31 NEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN________
P62899 T22 Sugiyama RPL31 APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62899 Y108 Sugiyama RPL31 LSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN___
P62899 Y25 Sugiyama RPL31 KKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRA
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 T143 Sugiyama RPL8 RGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANR
P62917 T146 Sugiyama RPL8 LARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANRAVV
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62942 Y27 Sugiyama FKBP1A FKBP1 FKBP12 tIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPF
P62979 S123 Sugiyama RPS27A UBA80 UBCEP1 LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK
P62979 S134 Sugiyama RPS27A UBA80 UBCEP1 IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T203 Sugiyama ACTG1 ACTG RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T304 Sugiyama ACTG1 ACTG KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P63261 T318 Sugiyama ACTG1 ACTG VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T319 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809 S209 Sugiyama YBX1 NSEP1 YB1 RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 T89 Sugiyama YBX1 NSEP1 YB1 RNGyGFINRNDtKEDVFVHQtAIKKNNPRKyLRsVGDGEtV
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T320 Sugiyama ACTC1 ACTC VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68104 T23 Sugiyama EEF1A1 EEF1A EF1A LENG7 KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
P68104 T261 Sugiyama EEF1A1 EEF1A EF1A LENG7 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T320 Sugiyama ACTA1 ACTA VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68363 T51 Sugiyama TUBA1B QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T80 Sugiyama TUBA1B KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68363 Y83 Sugiyama TUBA1B PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P68431 T46 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P78371 S60 Sugiyama CCT2 99D8.1 CCTB KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P78371 T69 Sugiyama CCT2 99D8.1 CCTB DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P84098 S12 Sugiyama RPL19 _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI
P84098 S13 Sugiyama RPL19 ________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEIA
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P84243 T46 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P99999 T50 Sugiyama CYCS CYC GPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEYLE
Q00341 T729 Sugiyama HDLBP HBP VGL VEKAKKQLLHLAEEKQTKSFtVDIRAKPEYHKFLIGKGGGK
Q00839 T530 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 KTTWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtG
Q00839 T532 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 TWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtGKL
Q00839 T549 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GtNtIMDKMMVAGFKKQMADtGKLNtLLQRAPQCLGKFIEI
Q00839 T554 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 MDKMMVAGFKKQMADtGKLNtLLQRAPQCLGKFIEIAARKK
Q00839 T582 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 CLGKFIEIAARKKRNFILDQtNVsAAAQRRKMCLFAGFQRK
Q01105 S168 Sugiyama SET ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01105 T169 Sugiyama SET NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q02539 T95 Sugiyama H1-1 H1F1 HIST1H1A DVEKNNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKAS
Q02539 T99 Sugiyama H1-1 H1F1 HIST1H1A NNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKASSVET
Q02543 S123 Sugiyama RPL18A AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK
Q02543 T101 Sugiyama RPL18A WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA
Q02543 T107 Sugiyama RPL18A RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02543 T24 Sugiyama RPL18A SGTLREYKVVGRCLPTPKCHtPPLYRMRIFAPNHVVAKSRF
Q02543 Y97 Sugiyama RPL18A NFGIWLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARH
Q02878 T118 Sugiyama RPL6 TXREB1 GDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQHVR
Q02878 T213 Sugiyama RPL6 TXREB1 FVIAtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIF
Q02878 T235 Sugiyama RPL6 TXREB1 AyFKKKKLRKPRHQEGEIFDtEKEKYEITEQRKIDQKAVDs
Q02878 T91 Sugiyama RPL6 TXREB1 RKYSAAKSKVEKKKKEKVLAtVtKPVGGDKNGGTRVVKLRK
Q04637 T1119 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI GGSGAKPSDAAsEAARPAtstLNRFsALQQAVPtEsTDNRR
Q05639 T23 Sugiyama EEF1A2 EEF1AL STN KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
Q05639 T261 Sugiyama EEF1A2 EEF1AL STN PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06830 S30 Sugiyama PRDX1 PAGA PAGB TDPX2 HPAPNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTF
Q06830 T183 Sugiyama PRDX1 PAGA PAGB TDPX2 FQFtDKHGEVCPAGWKPGsDtIKPDVQKSKEyFSKQK____
Q07020 T122 Sugiyama RPL18 ALRVTSRARSRILRAGGKILtFDQLALDsPKGCGtVLLsGP
Q07020 T136 Sugiyama RPL18 AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07020 T39 Sugiyama RPL18 KSQDIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRP
Q07020 T42 Sugiyama RPL18 DIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRPPLs
Q07020 T79 Sugiyama RPL18 PPLsLsRMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLK
Q07020 T85 Sugiyama RPL18 RMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRV
Q07021 T163 Sugiyama C1QBP GC1QBP HABP1 SF2P32 FDGEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALV
Q07021 T165 Sugiyama C1QBP GC1QBP HABP1 SF2P32 GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD
Q07157 T1167 Sugiyama TJP1 ZO1 EQAPRAsALRHEEQPAPGyDtHGRLRPEAQPHPsAGPKPAE
Q12851 S170 SIGNOR MAP4K2 GCK RAB8IP VKLADFGVSGELTASVAKRRsFIGtPyWMAPEVAAVERKGG
Q12851 S328 Sugiyama MAP4K2 GCK RAB8IP DMFPDtIHSRGQHGPAERtPsEIQFHQVKFGAPRRKEtDPL
Q12851 S365 Sugiyama MAP4K2 GCK RAB8IP tDPLNEPWEEEWtLLGKEELsGsLLQSVQEALEERSLtIRs
Q12851 S367 Sugiyama MAP4K2 GCK RAB8IP PLNEPWEEEWtLLGKEELsGsLLQSVQEALEERSLtIRsAs
Q12851 S39 Sugiyama MAP4K2 GCK RAB8IP LQRVGAGtyGDVYKARDtVtsELAAVKIVKLDPGDDISsLQ
Q12851 S475 Sugiyama MAP4K2 GCK RAB8IP ERSSCHGLPPTPKVHMGACFsKVFNGCPLRIHAAVTWIHPV
Q12851 S57 Sugiyama MAP4K2 GCK RAB8IP VtsELAAVKIVKLDPGDDISsLQQEItILRECRHPNVVAYI
Q12851 S768 Sugiyama MAP4K2 GCK RAB8IP TVVCLQDSVLAFWSHGMQGRsLDtNEVTQEITDETRIFRVL
Q12851 T174 Sugiyama MAP4K2 GCK RAB8IP DFGVSGELTASVAKRRsFIGtPyWMAPEVAAVERKGGYNEL
Q12851 T26 Sugiyama MAP4K2 GCK RAB8IP DVSLQDPRDRFELLQRVGAGtyGDVYKARDtVtsELAAVKI
Q12851 T296 Sugiyama MAP4K2 GCK RAB8IP QLPRALLTQLLDKASDPHLGtPsPEDCELEtyDMFPDtIHS
Q12851 T313 Sugiyama MAP4K2 GCK RAB8IP HLGtPsPEDCELEtyDMFPDtIHSRGQHGPAERtPsEIQFH
Q12851 T326 Sugiyama MAP4K2 GCK RAB8IP tyDMFPDtIHSRGQHGPAERtPsEIQFHQVKFGAPRRKEtD
Q12851 T345 Sugiyama MAP4K2 GCK RAB8IP RtPsEIQFHQVKFGAPRRKEtDPLNEPWEEEWtLLGKEELs
Q12851 T357 Sugiyama MAP4K2 GCK RAB8IP FGAPRRKEtDPLNEPWEEEWtLLGKEELsGsLLQSVQEALE
Q12851 T36 Sugiyama MAP4K2 GCK RAB8IP FELLQRVGAGtyGDVYKARDtVtsELAAVKIVKLDPGDDIS
Q12851 T38 Sugiyama MAP4K2 GCK RAB8IP LLQRVGAGtyGDVYKARDtVtsELAAVKIVKLDPGDDISsL
Q12851 T63 Sugiyama MAP4K2 GCK RAB8IP AVKIVKLDPGDDISsLQQEItILRECRHPNVVAYIGSYLRN
Q12851 T771 Sugiyama MAP4K2 GCK RAB8IP CLQDSVLAFWSHGMQGRsLDtNEVTQEITDETRIFRVLGAH
Q12851 Y176 Sugiyama MAP4K2 GCK RAB8IP GVSGELTASVAKRRsFIGtPyWMAPEVAAVERKGGYNELCD
Q12851 Y27 Sugiyama MAP4K2 GCK RAB8IP VSLQDPRDRFELLQRVGAGtyGDVYKARDtVtsELAAVKIV
Q12851 Y307 Sugiyama MAP4K2 GCK RAB8IP DKASDPHLGtPsPEDCELEtyDMFPDtIHSRGQHGPAERtP
Q12851 Y820 Sugiyama MAP4K2 GCK RAB8IP PTDNPEAHSNLYILTGHQSty____________________
Q12965 S943 Sugiyama MYO1E MYO1C GLPKNSRPTRRNttQNtGySsGtQNANyPVRAAPPPPGyHQ
Q12965 T935 Sugiyama MYO1E MYO1C VLQVSIGPGLPKNSRPTRRNttQNtGySsGtQNANyPVRAA
Q13069 S7 Sugiyama GAGE5 ______________MSWRGRsTyyWPRPRRYVQPPEVIGPM
Q13070 S7 Sugiyama GAGE6 ______________MSWRGRsTyyWPRPRRYVQPPEVIGPM
Q13136 T572 Sugiyama PPFIA1 LIP1 LRRPQKGRLAALRDEPSKVQtLNEQDWERAQQASVLANVAQ
Q13200 S361 SIGNOR|PSP PSMD2 TRAP2 EPKVPDDIyKtHLENNRFGGsGsQVDSARMNLASSFVNGFV
Q13442 S178 Sugiyama PDAP1 HASPP28 EEERKAKDDATLsGKRMQsLsLNK_________________
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13509 T72 Sugiyama TUBB3 TUBB4 NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF
Q13642 T64 Sugiyama FHL1 SLIM1 RKPIGADSKEVHYKNRFWHDtCFRCAKCLHPLANEtFVAKD
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q13885 T72 Sugiyama TUBB2A TUBB2 NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S1188 Sugiyama EIF3A EIF3S10 KIAA0139 PWRPLVKPGGWREKEKAREEsWGPPRESRPsEEREWDREKE
Q14152 T1379 Sugiyama EIF3A EIF3S10 KIAA0139 EKDREsLRRTKNEtDEDGWttVRR_________________
Q14152 T735 Sugiyama EIF3A EIF3S10 KIAA0139 EEQRIKDMDLWEQQEEERIttMQLEREKALEHKNRMSRMLE
Q14240 T81 Sugiyama EIF4A2 DDX2B EIF4F QRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEFKE
Q14247 T68 Sugiyama CTTN EMS1 GHQEHINIHKLRENVFQEHQtLKEKELETGPKASHGyGGKF
Q14498 T175 Sugiyama RBM39 HCC1 RNPC2 VFCMQLAARIRPRDLEEFFStVGKVRDVRMISDRNSRRSKG
Q14568 T171 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 ITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILHLK
Q15084 T395 Sugiyama PDIA6 ERP5 P5 TXNDC7 sFsEQGINEFLRELsFGRGstAPVGGGAFPtIVEREPWDGR
Q15084 T405 Sugiyama PDIA6 ERP5 P5 TXNDC7 LRELsFGRGstAPVGGGAFPtIVEREPWDGRDGELPVEDDI
Q15293 T211 Sugiyama RCN1 RCN FTAFLHPEEFEHMKEIVVLEtLEDIDKNGDGFVDQDEyIAD
Q15293 T71 Sugiyama RCN1 RCN EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI
Q16658 T239 Sugiyama FSCN1 FAN1 HSN SNL GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs
Q16658 T79 Sugiyama FSCN1 FAN1 HSN SNL AVCLRSHLGRyLAADKDGNVtCEREVPGPDCRFLIVAHDDG
Q16695 T46 Sugiyama H3-4 H3FT HIST3H3 ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q16775 T292 Sugiyama HAGH GLO2 HAGH1 FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____
Q2VIR3 T22 Sugiyama EIF2S3B AGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAtI
Q2VIR3 T41 Sugiyama EIF2S3B ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
Q2VIR3 T46 Sugiyama EIF2S3B tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHT
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q58FF7 T489 Sugiyama HSP90AB3P HSP90BC YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME
Q5VTE0 T23 Sugiyama EEF1A1P5 EEF1AL3 KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
Q5VTE0 T261 Sugiyama EEF1A1P5 EEF1AL3 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q6NXT2 T45 Sugiyama H3-5 H3F3C AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6PEY2 T51 Sugiyama TUBA3E QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q71DI3 T46 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71U36 T51 Sugiyama TUBA1A TUBA3 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T80 Sugiyama TUBA1A TUBA3 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71U36 Y83 Sugiyama TUBA1A TUBA3 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7Z739 T177 Sugiyama YTHDF3 YPPSSLGRAITDGQAGFGNDtLSKVPGISsIEQGMTGLKIG
Q86V81 T148 Sugiyama ALYREF ALY BEF THOC4 EFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQYNG
Q8IVH8 S549 Sugiyama MAP4K3 RAB8IPL1 PKPISNGLPPTPKVHMGACFsKVFNGCPLKIHCASSWINPD
Q8IVH8 T174 Sugiyama MAP4K3 RAB8IPL1 DFGVSAQITATIAKRKsFIGtPyWMAPEVAAVERKGGYNQL
Q8IVH8 Y176 Sugiyama MAP4K3 RAB8IPL1 GVSAQITATIAKRKsFIGtPyWMAPEVAAVERKGGYNQLCD
Q8NFD5 S1744 Sugiyama ARID1B BAF250B DAN15 KIAA1235 OSA2 ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8TD47 T247 Sugiyama RPS4Y2 RPS4Y2P VIGNGNKPWISLPRGKGIRLtIAEERDKRLAAKQSSG____
Q92598 T63 Sugiyama HSPH1 HSP105 HSP110 KIAA0201 SKNRTIGVAAKNQQITHANNtVsNFKRFHGRAFNDPFIQKE
Q96AY3 T200 Sugiyama FKBP10 FKBP65 PSEC0056 HYNGTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLG
Q96AY3 T203 Sugiyama FKBP10 FKBP65 PSEC0056 GTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLGMCP
Q96QK1 T773 Sugiyama VPS35 MEM3 TCCCTA00141 DLPNLEssEEtEQINKHFHNtLEHLRLRREsPEsEGPIyEG
Q99543 S275 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 RAQRKKEEMNRIRtLVDNAysCDPRIKKFKEEEKAKKEAEK
Q99543 T268 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 EKQNRATRAQRKKEEMNRIRtLVDNAysCDPRIKKFKEEEK
Q99575 T134 Sugiyama POP1 KIAA0061 EISAMLKAVTQKssNsLVFQtLPRHMRRRAMSHNVKRLPRR
Q99575 T189 Sugiyama POP1 KIAA0061 QKKEHSKNKCHKARRCHMNRtLEFNRRQKKNIWLETHIWHA
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99832 T458 Sugiyama CCT7 CCTH NIP7-1 yAKALEIIPRQLCDNAGFDAtNILNKLRARHAQGGTWYGVD
Q99832 T57 Sugiyama CCT7 CCTH NIP7-1 RTTLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAK
Q99832 T64 Sugiyama CCT7 CCTH NIP7-1 GMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTLVDIAK
Q9BQE3 T51 Sugiyama TUBA1C TUBA6 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T80 Sugiyama TUBA1C TUBA6 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BQE3 Y83 Sugiyama TUBA1C TUBA6 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BUJ2 S512 Sugiyama HNRNPUL1 E1BAP5 HNRPUL1 IQIAARKKRNyILDQtNVyGsAQRRKMRPFEGFQRKAIVIC
Q9BUJ2 T507 Sugiyama HNRNPUL1 E1BAP5 HNRPUL1 CLNRLIQIAARKKRNyILDQtNVyGsAQRRKMRPFEGFQRK
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BVA1 T72 Sugiyama TUBB2B NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BZI7 T153 Sugiyama UPF3B RENT3B UPF3X FAPFQKAAKKKTKKRDTKVGtIDDDPEyRKFLEsyAtDNEK
Q9H0C5 S273 Sugiyama BTBD1 C15orf1 NS5ATP8 QRQQLPVTFGNKQKVLGKALsLIRFPLMTIEEFAAGPAQSG
Q9H0H5 T251 Sugiyama RACGAP1 KIAA1478 MGCRACGAP EAVSTIETVPYWtRSRRKtGtLQPWNsDstLNSRQLEPRTE
Q9H0H5 T260 Sugiyama RACGAP1 KIAA1478 MGCRACGAP PYWtRSRRKtGtLQPWNsDstLNSRQLEPRTETDsVGtPQs
Q9HB71 T209 Sugiyama CACYBP S100A6BP SIP PNAS-107 EGLMNVLKKIyEDGDDDMKRtINKAWVESREKQAKGDTEF_
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ39 T159 Sugiyama RPS10P5 RPS10L RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9NR30 S706 Sugiyama DDX21 PTASVTEIQEKWHDSRRWQLsVATEQPELEGPREGYGGFRG
Q9NYV4 S303 Sugiyama CDK12 CRK7 CRKRS KIAA0904 sAYQsstRsPsPYSRRQRsVsPYSRRRSSSYERsGsysGRs
Q9UBR2 T172 Sugiyama CTSZ ETCNNYQAKDQECDKFNQCGtCNEFKECHAIRNYTLWRVGD
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UI15 Y192 Sugiyama TAGLN3 NP25 NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UNX3 T93 Sugiyama RPL26L1 RPL26P1 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
Q9UQ80 T200 Sugiyama PA2G4 EBP1 TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV
Q9UQ80 T386 Sugiyama PA2G4 EBP1 tQKKKKKKAsKtAENAtsGEtLEENEAGD____________
Q9Y295 T62 Sugiyama DRG1 NEDD3 LITPKGGGGGGPGEGFDVAKtGDARIGFVGFPSVGKSTLLS
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2B0 T79 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NPDGsQsVVEVPyARsEAHLtELLEEICDRMKEyGEQIDPs
Q9Y2T7 T124 Sugiyama YBX2 CSDA3 MSY2 RNGyGFINRNDtKEDVFVHQtAIKRNNPRKFLRsVGDGEtV
Q9Y2W1 T227 Sugiyama THRAP3 BCLAF2 TRAP150 sGGtsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRER
Q9Y2W1 T230 Sugiyama THRAP3 BCLAF2 TRAP150 tsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERsPA
Q9Y2W1 Y228 Sugiyama THRAP3 BCLAF2 TRAP150 GGtsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERs
Q9Y2X3 S434 Sugiyama NOP58 NOL5 NOP5 HSPC120 AKTEKYEHKSEVKtyDPSGDstLPtCsKKRKIEQVDKEDEI
Q9Y383 S347 Sugiyama LUC7L2 CGI-59 CGI-74 SRERSKRRSSKERFRDQDLAsCDRDRssRDRSPRDRDRKDK
Q9Y3F4 T48 Sugiyama STRAP MAWD UNRIP YGYFLISACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLN
Q9Y3F4 T54 Sugiyama STRAP MAWD UNRIP SACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLNKDATKA
Q9Y3U8 S91 Sugiyama RPL36 KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y4L1 S742 Sugiyama HYOU1 GRP170 HSPH4 ORP150 KLQDLTLRDLEKQEREKAANsLEAFIFEtQDKLyQPEyQEV
Q9Y4L1 T750 Sugiyama HYOU1 GRP170 HSPH4 ORP150 DLEKQEREKAANsLEAFIFEtQDKLyQPEyQEVsTEEQREE
Q9Y5L4 S57 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW
Q9Y5L4 T79 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B DNSEQKCIAMCMDRyMDAWNtVsRAYNSRLQRERANM____
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Transcriptional regulation by small RNAs R-HSA-5578749 1.065540e-09 8.972 0 0
Signal Transduction R-HSA-162582 3.204022e-08 7.494 0 0
Mitotic Prophase R-HSA-68875 3.895005e-08 7.409 0 0
Gene Silencing by RNA R-HSA-211000 1.111466e-07 6.954 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.868261e-07 6.313 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 6.678595e-07 6.175 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 8.517570e-07 6.070 0 0
Cell-Cell communication R-HSA-1500931 9.987958e-07 6.001 0 0
Packaging Of Telomere Ends R-HSA-171306 1.136679e-06 5.944 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.136679e-06 5.944 0 0
Defective pyroptosis R-HSA-9710421 1.364603e-06 5.865 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.769771e-06 5.752 0 0
DNA methylation R-HSA-5334118 1.908795e-06 5.719 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 2.442874e-06 5.612 0 0
Diseases of programmed cell death R-HSA-9645723 2.568356e-06 5.590 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.207459e-06 5.494 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.922925e-06 5.406 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 3.922925e-06 5.406 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 3.511683e-06 5.454 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 4.036649e-06 5.394 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 3.911289e-06 5.408 0 0
Signaling by Hippo R-HSA-2028269 3.608277e-06 5.443 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 4.018468e-06 5.396 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 3.911289e-06 5.408 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 4.774190e-06 5.321 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 4.837207e-06 5.315 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 4.897123e-06 5.310 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 6.412453e-06 5.193 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 8.211030e-06 5.086 0 0
Meiotic synapsis R-HSA-1221632 8.211030e-06 5.086 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 7.529558e-06 5.123 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 7.529558e-06 5.123 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.130499e-05 4.947 0 0
HDACs deacetylate histones R-HSA-3214815 1.126738e-05 4.948 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.145706e-05 4.941 0 0
Nucleosome assembly R-HSA-774815 1.190979e-05 4.924 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.190979e-05 4.924 0 0
HATs acetylate histones R-HSA-3214847 1.205209e-05 4.919 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.412335e-05 4.850 0 0
DNA Double Strand Break Response R-HSA-5693606 1.316566e-05 4.881 0 0
Apoptotic execution phase R-HSA-75153 1.412335e-05 4.850 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.373875e-05 4.862 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.378659e-05 4.861 0 0
Cleavage of the damaged purine R-HSA-110331 1.373875e-05 4.862 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.509426e-05 4.821 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.589500e-05 4.799 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.576206e-05 4.802 0 0
Depurination R-HSA-73927 1.661059e-05 4.780 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.664748e-05 4.779 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.764050e-05 4.753 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.771071e-05 4.752 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.998401e-05 4.699 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.970842e-05 4.705 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.027545e-05 4.693 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 2.180577e-05 4.661 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 2.180577e-05 4.661 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 2.244774e-05 4.649 0 0
Cellular Senescence R-HSA-2559583 2.212875e-05 4.655 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.361287e-05 4.627 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 2.392941e-05 4.621 0 0
HCMV Early Events R-HSA-9609690 2.402169e-05 4.619 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 2.852463e-05 4.545 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.894223e-05 4.538 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 3.268058e-05 4.486 0 0
Meiotic recombination R-HSA-912446 3.138531e-05 4.503 0 0
Cell junction organization R-HSA-446728 3.279215e-05 4.484 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 3.645696e-05 4.438 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.964908e-05 4.402 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 4.001574e-05 4.398 0 0
Depyrimidination R-HSA-73928 4.001574e-05 4.398 0 0
Nuclear import of Rev protein R-HSA-180746 4.783421e-05 4.320 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 5.740162e-05 4.241 0 0
Signaling by NOTCH R-HSA-157118 5.973203e-05 4.224 0 0
Nuclear Envelope Breakdown R-HSA-2980766 7.379732e-05 4.132 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 8.142651e-05 4.089 0 0
M Phase R-HSA-68886 9.421393e-05 4.026 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 9.629838e-05 4.016 0 0
HCMV Late Events R-HSA-9610379 9.906127e-05 4.004 0 0
Signaling by ERBB2 R-HSA-1227986 1.091368e-04 3.962 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.148461e-04 3.940 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 1.329335e-04 3.876 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.329335e-04 3.876 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.363213e-04 3.865 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.552236e-04 3.809 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.696702e-04 3.770 0 0
RNA Polymerase I Transcription R-HSA-73864 2.097531e-04 3.678 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 2.265778e-04 3.645 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.275440e-04 3.643 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.320043e-04 3.635 0 0
Long-term potentiation R-HSA-9620244 2.767899e-04 3.558 0 0
Assembly of the pre-replicative complex R-HSA-68867 3.021911e-04 3.520 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.145086e-04 3.502 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 3.188068e-04 3.496 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 3.816800e-04 3.418 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.644678e-04 3.438 0 0
Metabolism of non-coding RNA R-HSA-194441 4.137734e-04 3.383 0 0
snRNP Assembly R-HSA-191859 4.137734e-04 3.383 0 0
Meiosis R-HSA-1500620 4.195742e-04 3.377 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 4.635142e-04 3.334 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 4.743937e-04 3.324 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 5.659674e-04 3.247 0 0
tRNA processing in the nucleus R-HSA-6784531 5.779497e-04 3.238 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 5.779497e-04 3.238 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 5.902341e-04 3.229 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 5.902341e-04 3.229 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 5.902341e-04 3.229 0 0
HCMV Infection R-HSA-9609646 6.197581e-04 3.208 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 6.428932e-04 3.192 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 6.666219e-04 3.176 0 0
Base Excision Repair R-HSA-73884 7.200036e-04 3.143 0 0
Cell Cycle, Mitotic R-HSA-69278 7.464668e-04 3.127 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 8.316299e-04 3.080 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 7.656611e-04 3.116 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 7.855836e-04 3.105 0 0
Ub-specific processing proteases R-HSA-5689880 8.214488e-04 3.085 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.012763e-03 2.994 0 0
Amyloid fiber formation R-HSA-977225 1.012763e-03 2.994 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.043579e-03 2.981 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 1.043579e-03 2.981 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.055360e-03 2.977 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.293687e-03 2.888 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.301790e-03 2.885 0 0
Axon guidance R-HSA-422475 1.302307e-03 2.885 0 0
Chromatin modifying enzymes R-HSA-3247509 1.501189e-03 2.824 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.632685e-03 2.787 0 0
Signaling by VEGF R-HSA-194138 1.675927e-03 2.776 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.692047e-03 2.772 0 0
G2/M Checkpoints R-HSA-69481 1.905096e-03 2.720 0 0
Deubiquitination R-HSA-5688426 1.757354e-03 2.755 0 0
Signal attenuation R-HSA-74749 1.913753e-03 2.718 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.979751e-03 2.703 0 0
Nervous system development R-HSA-9675108 2.168227e-03 2.664 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.278806e-03 2.642 0 0
Activation of HOX genes during differentiation R-HSA-5619507 2.663271e-03 2.575 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 2.663271e-03 2.575 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.772185e-03 2.557 0 0
IRS activation R-HSA-74713 2.855788e-03 2.544 0 0
Chromatin organization R-HSA-4839726 2.925453e-03 2.534 0 0
Cell-cell junction organization R-HSA-421270 3.181630e-03 2.497 0 0
RAF/MAP kinase cascade R-HSA-5673001 3.390423e-03 2.470 0 0
Interleukin-37 signaling R-HSA-9008059 3.402851e-03 2.468 0 0
Nephrin family interactions R-HSA-373753 3.435794e-03 2.464 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 4.003780e-03 2.398 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.964017e-03 2.402 0 0
Signaling by LTK R-HSA-9842663 4.003780e-03 2.398 0 0
MAPK family signaling cascades R-HSA-5683057 3.649498e-03 2.438 0 0
Estrogen-dependent gene expression R-HSA-9018519 3.678228e-03 2.434 0 0
Adherens junctions interactions R-HSA-418990 3.575078e-03 2.447 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.140824e-03 2.383 0 0
Cell Cycle Checkpoints R-HSA-69620 4.231110e-03 2.374 0 0
Telomere Maintenance R-HSA-157579 4.405372e-03 2.356 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 4.414533e-03 2.355 0 0
Oncogenic MAPK signaling R-HSA-6802957 4.484464e-03 2.348 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 4.830148e-03 2.316 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 4.830148e-03 2.316 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 5.039040e-03 2.298 0 0
Glycolysis R-HSA-70171 5.369305e-03 2.270 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 5.383174e-03 2.269 0 0
Protein ubiquitination R-HSA-8852135 6.483866e-03 2.188 0 0
Cell Cycle R-HSA-1640170 6.655676e-03 2.177 0 0
Homology Directed Repair R-HSA-5693538 7.202511e-03 2.143 0 0
Cell-extracellular matrix interactions R-HSA-446353 7.261984e-03 2.139 0 0
TCF dependent signaling in response to WNT R-HSA-201681 7.648975e-03 2.116 0 0
Signaling by PTK6 R-HSA-8848021 8.048164e-03 2.094 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 8.048164e-03 2.094 0 0
Type I hemidesmosome assembly R-HSA-446107 9.869738e-03 2.006 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 9.869738e-03 2.006 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 9.400484e-03 2.027 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 9.452921e-03 2.024 0 0
Chromosome Maintenance R-HSA-73886 8.501692e-03 2.070 0 0
Cellular response to heat stress R-HSA-3371556 8.501692e-03 2.070 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 1.019490e-02 1.992 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.019490e-02 1.992 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.122555e-02 1.950 0 0
Regulation of TP53 Expression R-HSA-6804754 1.122555e-02 1.950 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.122555e-02 1.950 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.122555e-02 1.950 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.122555e-02 1.950 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.122555e-02 1.950 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.122555e-02 1.950 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.122555e-02 1.950 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.122555e-02 1.950 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.122555e-02 1.950 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.122555e-02 1.950 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.122555e-02 1.950 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.122555e-02 1.950 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.123558e-02 1.949 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.124583e-02 1.949 0 0
Inositol phosphate metabolism R-HSA-1483249 1.160974e-02 1.935 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.173418e-02 1.931 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.173684e-02 1.930 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.191128e-02 1.924 0 0
Pyroptosis R-HSA-5620971 1.201642e-02 1.920 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.244976e-02 1.905 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.380261e-02 1.860 0 0
Regulation of CDH11 function R-HSA-9762292 1.538025e-02 1.813 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.292646e-02 1.889 0 0
Synaptic adhesion-like molecules R-HSA-8849932 1.380261e-02 1.860 0 0
Post NMDA receptor activation events R-HSA-438064 1.548324e-02 1.810 0 0
Reproduction R-HSA-1474165 1.488724e-02 1.827 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.477474e-02 1.830 0 0
ESR-mediated signaling R-HSA-8939211 1.553106e-02 1.809 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 1.587439e-02 1.799 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.589719e-02 1.799 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.589719e-02 1.799 0 0
Glucose metabolism R-HSA-70326 1.671288e-02 1.777 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.709213e-02 1.767 0 0
Cellular responses to stress R-HSA-2262752 1.796577e-02 1.746 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.813154e-02 1.742 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.839792e-02 1.735 0 0
Interleukin-2 signaling R-HSA-9020558 1.866638e-02 1.729 0 0
Programmed Cell Death R-HSA-5357801 1.914695e-02 1.718 0 0
DNA Replication R-HSA-69306 2.045459e-02 1.689 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 2.176031e-02 1.662 0 0
Signaling by ALK in cancer R-HSA-9700206 2.176031e-02 1.662 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 2.220481e-02 1.654 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 2.231103e-02 1.651 0 0
Activation of RAC1 R-HSA-428540 2.231103e-02 1.651 0 0
Striated Muscle Contraction R-HSA-390522 2.242627e-02 1.649 0 0
Cellular responses to stimuli R-HSA-8953897 2.297226e-02 1.639 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.321861e-02 1.634 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.398641e-02 1.620 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 2.398641e-02 1.620 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 2.398641e-02 1.620 0 0
MTF1 activates gene expression R-HSA-5660489 2.398641e-02 1.620 0 0
Sensory processing of sound R-HSA-9659379 2.400692e-02 1.620 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 2.543147e-02 1.595 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.544843e-02 1.594 0 0
mTORC1-mediated signalling R-HSA-166208 2.605538e-02 1.584 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 2.605538e-02 1.584 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 2.631496e-02 1.580 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.631496e-02 1.580 0 0
Oncogene Induced Senescence R-HSA-2559585 2.688600e-02 1.570 0 0
Influenza Infection R-HSA-168255 2.830823e-02 1.548 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 3.182025e-02 1.497 0 0
Deadenylation of mRNA R-HSA-429947 3.232817e-02 1.490 0 0
Sema4D in semaphorin signaling R-HSA-400685 3.576760e-02 1.447 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 3.182025e-02 1.497 0 0
Epigenetic regulation of gene expression R-HSA-212165 3.457156e-02 1.461 0 0
Interferon Signaling R-HSA-913531 3.388227e-02 1.470 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 3.067706e-02 1.513 0 0
Apoptosis R-HSA-109581 2.921412e-02 1.534 0 0
Regulated Necrosis R-HSA-5218859 3.323553e-02 1.478 0 0
NrCAM interactions R-HSA-447038 3.182025e-02 1.497 0 0
L1CAM interactions R-HSA-373760 3.634116e-02 1.440 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.800931e-02 1.420 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 3.872714e-02 1.412 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 3.872714e-02 1.412 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 3.872714e-02 1.412 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 3.872714e-02 1.412 0 0
Myogenesis R-HSA-525793 3.941043e-02 1.404 0 0
SARS-CoV-2 Infection R-HSA-9694516 3.959633e-02 1.402 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 4.037570e-02 1.394 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 4.051076e-02 1.392 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 4.051076e-02 1.392 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 4.051076e-02 1.392 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 4.051076e-02 1.392 0 0
Interaction between L1 and Ankyrins R-HSA-445095 4.325702e-02 1.364 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 4.325702e-02 1.364 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 4.329034e-02 1.364 0 0
Signaling by EGFR R-HSA-177929 4.356121e-02 1.361 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 4.413919e-02 1.355 0 0
Muscle contraction R-HSA-397014 4.575135e-02 1.340 0 0
Signaling by ERBB4 R-HSA-1236394 4.656583e-02 1.332 0 0
Centrosome maturation R-HSA-380287 4.907616e-02 1.309 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 4.916929e-02 1.308 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 4.998006e-02 1.301 0 0
MTOR signalling R-HSA-165159 5.012997e-02 1.300 0 0
Host Interactions of HIV factors R-HSA-162909 5.048000e-02 1.297 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.156045e-02 1.288 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 5.156045e-02 1.288 0 0
Co-inhibition by PD-1 R-HSA-389948 5.628837e-02 1.250 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.632309e-02 1.249 0 0
Cytokine Signaling in Immune system R-HSA-1280215 5.673983e-02 1.246 0 0
SOS-mediated signalling R-HSA-112412 6.015500e-02 1.221 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 6.015500e-02 1.221 0 0
MECP2 regulates transcription factors R-HSA-9022707 6.015500e-02 1.221 0 0
EGFR downregulation R-HSA-182971 6.067115e-02 1.217 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 7.595675e-02 1.119 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 7.595675e-02 1.119 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 7.595675e-02 1.119 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 7.096690e-02 1.149 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 7.096690e-02 1.149 0 0
RAF activation R-HSA-5673000 8.125274e-02 1.090 0 0
Signaling downstream of RAS mutants R-HSA-9649948 6.510561e-02 1.186 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 6.510561e-02 1.186 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 6.510561e-02 1.186 0 0
Integrin signaling R-HSA-354192 7.057530e-02 1.151 0 0
Signaling by RAS mutants R-HSA-6802949 6.510561e-02 1.186 0 0
IGF1R signaling cascade R-HSA-2428924 6.855048e-02 1.164 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 7.215552e-02 1.142 0 0
Inhibition of PKR R-HSA-169131 7.595675e-02 1.119 0 0
Unwinding of DNA R-HSA-176974 8.235136e-02 1.084 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 6.411769e-02 1.193 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 8.500486e-02 1.071 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 8.500486e-02 1.071 0 0
Ephrin signaling R-HSA-3928664 6.411769e-02 1.193 0 0
Signaling by WNT R-HSA-195721 8.486649e-02 1.071 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 7.057530e-02 1.151 0 0
Protein-protein interactions at synapses R-HSA-6794362 7.887551e-02 1.103 0 0
DNA Repair R-HSA-73894 8.082873e-02 1.092 0 0
Semaphorin interactions R-HSA-373755 6.505249e-02 1.187 0 0
SLC-mediated bile acid transport R-HSA-9958517 7.096690e-02 1.149 0 0
Signaling by TGFBR3 R-HSA-9839373 6.510561e-02 1.186 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 8.207657e-02 1.086 0 0
Interleukin-1 family signaling R-HSA-446652 7.839890e-02 1.106 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 8.516477e-02 1.070 0 0
HIV Life Cycle R-HSA-162587 9.122297e-02 1.040 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 9.275502e-02 1.033 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.275502e-02 1.033 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 9.275502e-02 1.033 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 9.275502e-02 1.033 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.275502e-02 1.033 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 9.416029e-02 1.026 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 9.416029e-02 1.026 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 9.424795e-02 1.026 0 0
PI3K/AKT activation R-HSA-198203 9.424795e-02 1.026 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 9.424795e-02 1.026 0 0
Signaling by Leptin R-HSA-2586552 9.424795e-02 1.026 0 0
Leishmania phagocytosis R-HSA-9664417 9.740324e-02 1.011 0 0
Parasite infection R-HSA-9664407 9.740324e-02 1.011 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.740324e-02 1.011 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 9.866100e-02 1.006 0 0
Translation initiation complex formation R-HSA-72649 1.016915e-01 0.993 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.066001e-01 0.972 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.066001e-01 0.972 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.066001e-01 0.972 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.087277e-01 0.964 0 0
Growth hormone receptor signaling R-HSA-982772 1.087277e-01 0.964 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 1.111482e-01 0.954 0 0
Signaling by ALK R-HSA-201556 1.111482e-01 0.954 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 1.117467e-01 0.952 0 0
XAV939 stabilizes AXIN R-HSA-5545619 1.117467e-01 0.952 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 1.117467e-01 0.952 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.117467e-01 0.952 0 0
Breakdown of the nuclear lamina R-HSA-352238 1.117467e-01 0.952 0 0
Ion homeostasis R-HSA-5578775 1.121586e-01 0.950 0 0
EPH-Ephrin signaling R-HSA-2682334 1.130090e-01 0.947 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.170857e-01 0.931 0 0
Neurodegenerative Diseases R-HSA-8863678 1.170857e-01 0.931 0 0
Diseases of Immune System R-HSA-5260271 1.176429e-01 0.929 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 1.176429e-01 0.929 0 0
Interleukin-2 family signaling R-HSA-451927 1.176429e-01 0.929 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.193548e-01 0.923 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.193548e-01 0.923 0 0
Immune System R-HSA-168256 1.214287e-01 0.916 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.242984e-01 0.906 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.242984e-01 0.906 0 0
Invadopodia formation R-HSA-8941237 1.792276e-01 0.747 0 0
Erythropoietin activates RAS R-HSA-9027284 1.734548e-01 0.761 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.734548e-01 0.761 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.734548e-01 0.761 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.875404e-01 0.727 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.875404e-01 0.727 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.525655e-01 0.817 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.525655e-01 0.817 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.715107e-01 0.766 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.711740e-01 0.767 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.711740e-01 0.767 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.425443e-01 0.846 0 0
mRNA Splicing R-HSA-72172 1.809927e-01 0.742 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 1.458767e-01 0.836 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.284903e-01 0.891 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.311097e-01 0.882 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.536955e-01 0.813 0 0
MAP2K and MAPK activation R-HSA-5674135 1.311097e-01 0.882 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 1.875404e-01 0.727 0 0
Killing mechanisms R-HSA-9664420 1.875404e-01 0.727 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.469534e-01 0.833 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.469534e-01 0.833 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.527041e-01 0.816 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.598057e-01 0.796 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 1.734548e-01 0.761 0 0
Signalling to ERK5 R-HSA-198765 1.461524e-01 0.835 0 0
Mitotic Anaphase R-HSA-68882 1.472227e-01 0.832 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.504142e-01 0.823 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 1.813601e-01 0.741 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 1.749458e-01 0.757 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.434969e-01 0.843 0 0
GPER1 signaling R-HSA-9634597 1.826937e-01 0.738 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.263872e-01 0.898 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.792276e-01 0.747 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 1.792276e-01 0.747 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.345615e-01 0.871 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.441223e-01 0.841 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.441223e-01 0.841 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.441223e-01 0.841 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.840869e-01 0.735 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.461524e-01 0.835 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 1.792276e-01 0.747 0 0
Regulation of KIT signaling R-HSA-1433559 1.595543e-01 0.797 0 0
TGFBR3 expression R-HSA-9839394 1.256750e-01 0.901 0 0
Ion transport by P-type ATPases R-HSA-936837 1.587801e-01 0.799 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.324624e-01 0.878 0 0
Ion channel transport R-HSA-983712 1.266618e-01 0.897 0 0
Signal regulatory protein family interactions R-HSA-391160 1.595543e-01 0.797 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.875404e-01 0.727 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.369390e-01 0.863 0 0
Signaling by ROBO receptors R-HSA-376176 1.736585e-01 0.760 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.870848e-01 0.728 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.872018e-01 0.728 0 0
Platelet calcium homeostasis R-HSA-418360 1.620921e-01 0.790 0 0
Signaling by Interleukins R-HSA-449147 1.566217e-01 0.805 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 1.458767e-01 0.836 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 1.595543e-01 0.797 0 0
tRNA processing R-HSA-72306 1.334781e-01 0.875 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.768838e-01 0.752 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 2.110234e-01 0.676 0 0
ATP sensitive Potassium channels R-HSA-1296025 2.110234e-01 0.676 0 0
Nucleotide catabolism defects R-HSA-9735786 2.110234e-01 0.676 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 2.110234e-01 0.676 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 2.110234e-01 0.676 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.110234e-01 0.676 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.110234e-01 0.676 0 0
Activation of AMPA receptors R-HSA-399710 2.415894e-01 0.617 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.415894e-01 0.617 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 2.709730e-01 0.567 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.709730e-01 0.567 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.709730e-01 0.567 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.709730e-01 0.567 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 2.709730e-01 0.567 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.992199e-01 0.524 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.992199e-01 0.524 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.263740e-01 0.486 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 3.263740e-01 0.486 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 3.263740e-01 0.486 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 2.017762e-01 0.695 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.161293e-01 0.665 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.524775e-01 0.453 0 0
WNT mediated activation of DVL R-HSA-201688 3.775710e-01 0.423 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 2.741399e-01 0.562 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.741399e-01 0.562 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 2.886659e-01 0.540 0 0
Notch-HLH transcription pathway R-HSA-350054 3.031571e-01 0.518 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.031571e-01 0.518 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.175946e-01 0.498 0 0
mRNA 3'-end processing R-HSA-72187 2.147332e-01 0.668 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 3.319608e-01 0.479 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 2.481645e-01 0.605 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 3.744768e-01 0.427 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 3.744768e-01 0.427 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 2.126667e-01 0.672 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 3.381031e-01 0.471 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 3.382633e-01 0.471 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 3.659850e-01 0.437 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 3.659850e-01 0.437 0 0
Signaling by EGFR in Cancer R-HSA-1643713 3.604160e-01 0.443 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.741399e-01 0.562 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.741399e-01 0.562 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.161293e-01 0.665 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.161293e-01 0.665 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.741399e-01 0.562 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 3.535466e-01 0.452 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.595999e-01 0.586 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 2.886659e-01 0.540 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 3.031571e-01 0.518 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 3.031571e-01 0.518 0 0
Insulin receptor signalling cascade R-HSA-74751 3.177191e-01 0.498 0 0
Regulation of gap junction activity R-HSA-191650 2.110234e-01 0.676 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 3.744768e-01 0.427 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.110234e-01 0.676 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 2.415894e-01 0.617 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 2.017762e-01 0.695 0 0
Tight junction interactions R-HSA-420029 3.462395e-01 0.461 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.001506e-01 0.699 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 3.604160e-01 0.443 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 2.110234e-01 0.676 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 2.110234e-01 0.676 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.709730e-01 0.567 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 3.263740e-01 0.486 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.775710e-01 0.423 0 0
Signalling to RAS R-HSA-167044 2.741399e-01 0.562 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.775710e-01 0.423 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.017762e-01 0.695 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.305694e-01 0.637 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.506963e-01 0.601 0 0
Mitophagy R-HSA-5205647 2.215214e-01 0.655 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.110234e-01 0.676 0 0
Reelin signalling pathway R-HSA-8866376 2.415894e-01 0.617 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.709730e-01 0.567 0 0
Synthesis of PS R-HSA-1483101 2.709730e-01 0.567 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.263740e-01 0.486 0 0
FGFR1b ligand binding and activation R-HSA-190370 3.524775e-01 0.453 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 3.775710e-01 0.423 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 3.319608e-01 0.479 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 2.314333e-01 0.636 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.382633e-01 0.471 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 2.738124e-01 0.563 0 0
Signalling to ERKs R-HSA-187687 2.318311e-01 0.635 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.886659e-01 0.540 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.415894e-01 0.617 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 2.844408e-01 0.546 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 2.844408e-01 0.546 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.462395e-01 0.461 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 2.110234e-01 0.676 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 3.263740e-01 0.486 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.263740e-01 0.486 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 3.775710e-01 0.423 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 2.739256e-01 0.562 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 2.215214e-01 0.655 0 0
RET signaling R-HSA-8853659 2.422259e-01 0.616 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 3.088999e-01 0.510 0 0
Kinesins R-HSA-983189 2.826132e-01 0.549 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 2.001506e-01 0.699 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.164888e-01 0.500 0 0
Leishmania infection R-HSA-9658195 2.161789e-01 0.665 0 0
Parasitic Infection Pathways R-HSA-9824443 2.161789e-01 0.665 0 0
NADE modulates death signalling R-HSA-205025 2.110234e-01 0.676 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.415894e-01 0.617 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 2.709730e-01 0.567 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.709730e-01 0.567 0 0
TGFBR3 PTM regulation R-HSA-9839383 3.524775e-01 0.453 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.305694e-01 0.637 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.775710e-01 0.423 0 0
ARMS-mediated activation R-HSA-170984 3.775710e-01 0.423 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 2.844408e-01 0.546 0 0
G alpha (12/13) signalling events R-HSA-416482 2.548922e-01 0.594 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 2.997976e-01 0.523 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 3.708782e-01 0.431 0 0
Mitotic Prometaphase R-HSA-68877 3.300740e-01 0.481 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 3.057882e-01 0.515 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 2.111522e-01 0.675 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.709730e-01 0.567 0 0
Metabolism of RNA R-HSA-8953854 2.010506e-01 0.697 0 0
MyD88-independent TLR4 cascade R-HSA-166166 2.111522e-01 0.675 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.775710e-01 0.423 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 2.012019e-01 0.696 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.526947e-01 0.597 0 0
NRAGE signals death through JNK R-HSA-193648 2.481645e-01 0.605 0 0
Signaling by FGFR1 in disease R-HSA-5655302 3.057882e-01 0.515 0 0
Recycling pathway of L1 R-HSA-437239 3.699196e-01 0.432 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 2.996340e-01 0.523 0 0
FGFR1 mutant receptor activation R-HSA-1839124 2.012019e-01 0.696 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 2.056233e-01 0.687 0 0
Toll-like Receptor Cascades R-HSA-168898 2.131467e-01 0.671 0 0
PKMTs methylate histone lysines R-HSA-3214841 2.951025e-01 0.530 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.450684e-01 0.611 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.110234e-01 0.676 0 0
Co-inhibition by BTLA R-HSA-9927353 2.415894e-01 0.617 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.415894e-01 0.617 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.709730e-01 0.567 0 0
CREB phosphorylation R-HSA-199920 2.992199e-01 0.524 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.263740e-01 0.486 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 3.263740e-01 0.486 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 3.263740e-01 0.486 0 0
Adrenoceptors R-HSA-390696 3.524775e-01 0.453 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 2.913416e-01 0.536 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 2.280595e-01 0.642 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 2.454106e-01 0.610 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 2.951025e-01 0.530 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 3.662102e-01 0.436 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 3.370893e-01 0.472 0 0
Stimuli-sensing channels R-HSA-2672351 2.001506e-01 0.699 0 0
HIV Infection R-HSA-162906 2.747070e-01 0.561 0 0
Signaling by NTRKs R-HSA-166520 2.142553e-01 0.669 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.415894e-01 0.617 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 2.709730e-01 0.567 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 2.709730e-01 0.567 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 2.992199e-01 0.524 0 0
Nef and signal transduction R-HSA-164944 2.992199e-01 0.524 0 0
Synthesis of PG R-HSA-1483148 2.017762e-01 0.695 0 0
Interleukin-1 processing R-HSA-448706 3.775710e-01 0.423 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.775710e-01 0.423 0 0
Signaling by NOTCH4 R-HSA-9013694 2.259534e-01 0.646 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.451763e-01 0.462 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 3.497225e-01 0.456 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 2.826132e-01 0.549 0 0
Apoptotic factor-mediated response R-HSA-111471 2.305694e-01 0.637 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.188767e-01 0.660 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 2.709730e-01 0.567 0 0
Signaling by FGFR1 R-HSA-5654736 2.481645e-01 0.605 0 0
Signaling by NOTCH3 R-HSA-9012852 2.396969e-01 0.620 0 0
Cardiac conduction R-HSA-5576891 2.290241e-01 0.640 0 0
Netrin-1 signaling R-HSA-373752 3.378998e-01 0.471 0 0
Signaling by FGFR4 R-HSA-5654743 3.271954e-01 0.485 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 3.775710e-01 0.423 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.886659e-01 0.540 0 0
TRP channels R-HSA-3295583 3.604160e-01 0.443 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 2.826132e-01 0.549 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 2.826132e-01 0.549 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 2.826132e-01 0.549 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 2.826132e-01 0.549 0 0
Signaling by FGFR3 R-HSA-5654741 3.485937e-01 0.458 0 0
TNF signaling R-HSA-75893 2.481645e-01 0.605 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.923289e-01 0.716 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 2.741399e-01 0.562 0 0
Syndecan interactions R-HSA-3000170 3.175946e-01 0.498 0 0
Signaling by TGFB family members R-HSA-9006936 2.741511e-01 0.562 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.744768e-01 0.427 0 0
Death Receptor Signaling R-HSA-73887 2.435602e-01 0.613 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 2.161293e-01 0.665 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 2.886659e-01 0.540 0 0
Regulation of TNFR1 signaling R-HSA-5357905 3.592695e-01 0.445 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 2.450684e-01 0.611 0 0
SARS-CoV Infections R-HSA-9679506 2.712910e-01 0.567 0 0
Response to metal ions R-HSA-5660526 2.017762e-01 0.695 0 0
IRE1alpha activates chaperones R-HSA-381070 2.126667e-01 0.672 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 3.265581e-01 0.486 0 0
Interleukin-7 signaling R-HSA-1266695 3.462395e-01 0.461 0 0
SLC transporter disorders R-HSA-5619102 3.111382e-01 0.507 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.805370e-01 0.420 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 3.884096e-01 0.411 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 3.884096e-01 0.411 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 3.885776e-01 0.411 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 3.885776e-01 0.411 0 0
Degradation of CDH1 R-HSA-9766229 3.911149e-01 0.408 0 0
DNA Damage Bypass R-HSA-73893 3.911149e-01 0.408 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.911149e-01 0.408 0 0
Interferon alpha/beta signaling R-HSA-909733 4.007614e-01 0.397 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.016468e-01 0.396 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.016935e-01 0.396 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 4.016935e-01 0.396 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 4.016935e-01 0.396 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 4.016935e-01 0.396 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 4.016935e-01 0.396 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 4.016935e-01 0.396 0 0
Signaling by Erythropoietin R-HSA-9006335 4.022033e-01 0.396 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 4.022033e-01 0.396 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 4.022033e-01 0.396 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 4.022033e-01 0.396 0 0
Membrane Trafficking R-HSA-199991 4.040056e-01 0.394 0 0
Developmental Biology R-HSA-1266738 4.094072e-01 0.388 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 4.156863e-01 0.381 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 4.158477e-01 0.381 0 0
DAP12 signaling R-HSA-2424491 4.158477e-01 0.381 0 0
Activation of the pre-replicative complex R-HSA-68962 4.158477e-01 0.381 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 4.158477e-01 0.381 0 0
Viral Infection Pathways R-HSA-9824446 4.207927e-01 0.376 0 0
G2/M Transition R-HSA-69275 4.210228e-01 0.376 0 0
Signaling by NOTCH1 R-HSA-1980143 4.237391e-01 0.373 0 0
Interleukin-12 signaling R-HSA-9020591 4.237391e-01 0.373 0 0
Signaling by APC mutants R-HSA-4839744 4.248825e-01 0.372 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 4.248825e-01 0.372 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 4.248825e-01 0.372 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 4.248825e-01 0.372 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 4.248825e-01 0.372 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.248825e-01 0.372 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 4.248825e-01 0.372 0 0
PECAM1 interactions R-HSA-210990 4.248825e-01 0.372 0 0
Prostanoid ligand receptors R-HSA-391908 4.248825e-01 0.372 0 0
Trafficking of AMPA receptors R-HSA-399719 4.293337e-01 0.367 0 0
Cargo concentration in the ER R-HSA-5694530 4.293337e-01 0.367 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 4.321081e-01 0.364 0 0
Mitotic G2-G2/M phases R-HSA-453274 4.321081e-01 0.364 0 0
Smooth Muscle Contraction R-HSA-445355 4.329061e-01 0.364 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 4.342131e-01 0.362 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.383824e-01 0.358 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.423172e-01 0.354 0 0
Signaling by WNT in cancer R-HSA-4791275 4.426531e-01 0.354 0 0
Diseases of mitotic cell cycle R-HSA-9675126 4.426531e-01 0.354 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 4.426531e-01 0.354 0 0
DNA strand elongation R-HSA-69190 4.426531e-01 0.354 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.431953e-01 0.353 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 4.471742e-01 0.350 0 0
Signaling by GSK3beta mutants R-HSA-5339716 4.471742e-01 0.350 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 4.471742e-01 0.350 0 0
Plasmalogen biosynthesis R-HSA-75896 4.471742e-01 0.350 0 0
Signaling by AMER1 mutants R-HSA-4839748 4.471742e-01 0.350 0 0
Signaling by AXIN mutants R-HSA-4839735 4.471742e-01 0.350 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 4.471742e-01 0.350 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.471742e-01 0.350 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.471742e-01 0.350 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.471742e-01 0.350 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.471742e-01 0.350 0 0
Interleukin-1 signaling R-HSA-9020702 4.536041e-01 0.343 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 4.557985e-01 0.341 0 0
Activation of ATR in response to replication stress R-HSA-176187 4.557985e-01 0.341 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 4.557985e-01 0.341 0 0
Regulation of necroptotic cell death R-HSA-5675482 4.557985e-01 0.341 0 0
MHC class II antigen presentation R-HSA-2132295 4.560566e-01 0.341 0 0
PKR-mediated signaling R-HSA-9833482 4.583807e-01 0.339 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 4.583807e-01 0.339 0 0
Formation of the cornified envelope R-HSA-6809371 4.628968e-01 0.335 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 4.635475e-01 0.334 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 4.635475e-01 0.334 0 0
Adaptive Immune System R-HSA-1280218 4.680868e-01 0.330 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 4.686031e-01 0.329 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.686031e-01 0.329 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 4.686031e-01 0.329 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 4.686031e-01 0.329 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 4.686031e-01 0.329 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 4.686031e-01 0.329 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 4.686031e-01 0.329 0 0
IRAK1 recruits IKK complex R-HSA-937039 4.686031e-01 0.329 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 4.686031e-01 0.329 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 4.686031e-01 0.329 0 0
Repression of WNT target genes R-HSA-4641265 4.686031e-01 0.329 0 0
GRB2 events in EGFR signaling R-HSA-179812 4.686031e-01 0.329 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.686031e-01 0.329 0 0
MET activates RAS signaling R-HSA-8851805 4.686031e-01 0.329 0 0
Interleukin-15 signaling R-HSA-8983432 4.686031e-01 0.329 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.686031e-01 0.329 0 0
Regulation of IFNG signaling R-HSA-877312 4.686031e-01 0.329 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 4.686031e-01 0.329 0 0
Disorders of Nervous System Development R-HSA-9697154 4.686031e-01 0.329 0 0
Pervasive developmental disorders R-HSA-9005895 4.686031e-01 0.329 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 4.686031e-01 0.329 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 4.686031e-01 0.329 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 4.687635e-01 0.329 0 0
Effects of PIP2 hydrolysis R-HSA-114508 4.687635e-01 0.329 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 4.687635e-01 0.329 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 4.736014e-01 0.325 0 0
Regulation of CDH1 Function R-HSA-9764561 4.736014e-01 0.325 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 4.762181e-01 0.322 0 0
ER to Golgi Anterograde Transport R-HSA-199977 4.765384e-01 0.322 0 0
Signaling by NOTCH2 R-HSA-1980145 4.815423e-01 0.317 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 4.815423e-01 0.317 0 0
NOD1/2 Signaling Pathway R-HSA-168638 4.815423e-01 0.317 0 0
RSV-host interactions R-HSA-9833110 4.836889e-01 0.315 0 0
Adenylate cyclase activating pathway R-HSA-170660 4.892027e-01 0.311 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 4.892027e-01 0.311 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 4.892027e-01 0.311 0 0
Frs2-mediated activation R-HSA-170968 4.892027e-01 0.311 0 0
Diseases of nucleotide metabolism R-HSA-9735804 4.892027e-01 0.311 0 0
FGFR1c ligand binding and activation R-HSA-190373 4.892027e-01 0.311 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 4.892027e-01 0.311 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 4.892027e-01 0.311 0 0
Platelet degranulation R-HSA-114608 4.900201e-01 0.310 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 4.934441e-01 0.307 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 4.941299e-01 0.306 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 4.941299e-01 0.306 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 4.941299e-01 0.306 0 0
MITF-M-dependent gene expression R-HSA-9856651 4.951805e-01 0.305 0 0
RAB geranylgeranylation R-HSA-8873719 5.032254e-01 0.298 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 5.065218e-01 0.295 0 0
GPVI-mediated activation cascade R-HSA-114604 5.065218e-01 0.295 0 0
Regulation of TP53 Degradation R-HSA-6804757 5.065218e-01 0.295 0 0
FLT3 signaling in disease R-HSA-9682385 5.065218e-01 0.295 0 0
Calmodulin induced events R-HSA-111933 5.065218e-01 0.295 0 0
CaM pathway R-HSA-111997 5.065218e-01 0.295 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 5.074945e-01 0.295 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 5.090049e-01 0.293 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 5.090049e-01 0.293 0 0
Physiological factors R-HSA-5578768 5.090049e-01 0.293 0 0
Malate-aspartate shuttle R-HSA-9856872 5.090049e-01 0.293 0 0
Non-canonical inflammasome activation R-HSA-9686114 5.090049e-01 0.293 0 0
HDL assembly R-HSA-8963896 5.090049e-01 0.293 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 5.129088e-01 0.290 0 0
MAP kinase activation R-HSA-450294 5.129088e-01 0.290 0 0
Collagen degradation R-HSA-1442490 5.129088e-01 0.290 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 5.171255e-01 0.286 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 5.187144e-01 0.285 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 5.187144e-01 0.285 0 0
Neutrophil degranulation R-HSA-6798695 5.206690e-01 0.283 0 0
Mitochondrial protein import R-HSA-1268020 5.224911e-01 0.282 0 0
Adipogenesis R-HSA-9843745 5.232693e-01 0.281 0 0
Interleukin-12 family signaling R-HSA-447115 5.252785e-01 0.280 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 5.280406e-01 0.277 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.280406e-01 0.277 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.280406e-01 0.277 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 5.280406e-01 0.277 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.280406e-01 0.277 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 5.280406e-01 0.277 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 5.280406e-01 0.277 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.280406e-01 0.277 0 0
p38MAPK events R-HSA-171007 5.280406e-01 0.277 0 0
Spry regulation of FGF signaling R-HSA-1295596 5.280406e-01 0.277 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 5.280406e-01 0.277 0 0
DCC mediated attractive signaling R-HSA-418885 5.280406e-01 0.277 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 5.298170e-01 0.276 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 5.301223e-01 0.276 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 5.307044e-01 0.275 0 0
Peptide chain elongation R-HSA-156902 5.333646e-01 0.273 0 0
Selective autophagy R-HSA-9663891 5.333646e-01 0.273 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 5.363275e-01 0.271 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.413412e-01 0.267 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 5.424894e-01 0.266 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 5.424894e-01 0.266 0 0
Disease R-HSA-1643685 5.460685e-01 0.263 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.463394e-01 0.263 0 0
Phosphorylation of the APC/C R-HSA-176412 5.463394e-01 0.263 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 5.463394e-01 0.263 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.463394e-01 0.263 0 0
Prolonged ERK activation events R-HSA-169893 5.463394e-01 0.263 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 5.463394e-01 0.263 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 5.463394e-01 0.263 0 0
Negative regulation of FLT3 R-HSA-9706369 5.463394e-01 0.263 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.463394e-01 0.263 0 0
Regulation of TP53 Activity R-HSA-5633007 5.556354e-01 0.255 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 5.572020e-01 0.254 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 5.639298e-01 0.249 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.639298e-01 0.249 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 5.639298e-01 0.249 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.639298e-01 0.249 0 0
Disorders of Developmental Biology R-HSA-9675151 5.639298e-01 0.249 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 5.654358e-01 0.248 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 5.654358e-01 0.248 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 5.654358e-01 0.248 0 0
Maturation of spike protein R-HSA-9694548 5.654358e-01 0.248 0 0
FLT3 Signaling R-HSA-9607240 5.654358e-01 0.248 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 5.682785e-01 0.245 0 0
Signaling by Insulin receptor R-HSA-74752 5.727248e-01 0.242 0 0
Eukaryotic Translation Elongation R-HSA-156842 5.727248e-01 0.242 0 0
Negative regulation of MAPK pathway R-HSA-5675221 5.765945e-01 0.239 0 0
Intra-Golgi traffic R-HSA-6811438 5.765945e-01 0.239 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 5.767644e-01 0.239 0 0
Separation of Sister Chromatids R-HSA-2467813 5.789200e-01 0.237 0 0
PTEN Regulation R-HSA-6807070 5.807572e-01 0.236 0 0
Unfolded Protein Response (UPR) R-HSA-381119 5.807572e-01 0.236 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 5.808391e-01 0.236 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 5.808391e-01 0.236 0 0
Hemostasis R-HSA-109582 5.829273e-01 0.234 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 5.875422e-01 0.231 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 5.875422e-01 0.231 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 5.875422e-01 0.231 0 0
Ca-dependent events R-HSA-111996 5.875422e-01 0.231 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 5.937303e-01 0.226 0 0
Interleukin-17 signaling R-HSA-448424 5.952098e-01 0.225 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 5.954244e-01 0.225 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 5.970938e-01 0.224 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 5.970938e-01 0.224 0 0
GAB1 signalosome R-HSA-180292 5.970938e-01 0.224 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 5.970938e-01 0.224 0 0
PKA activation in glucagon signalling R-HSA-164378 5.970938e-01 0.224 0 0
Mismatch Repair R-HSA-5358508 5.970938e-01 0.224 0 0
FGFR1 ligand binding and activation R-HSA-190242 5.970938e-01 0.224 0 0
PKA activation R-HSA-163615 5.970938e-01 0.224 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 5.970938e-01 0.224 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 5.970938e-01 0.224 0 0
Platelet sensitization by LDL R-HSA-432142 5.970938e-01 0.224 0 0
Tie2 Signaling R-HSA-210993 5.970938e-01 0.224 0 0
Signaling by SCF-KIT R-HSA-1433557 5.982787e-01 0.223 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.028297e-01 0.220 0 0
Eukaryotic Translation Termination R-HSA-72764 6.028297e-01 0.220 0 0
Regulation of mitotic cell cycle R-HSA-453276 6.037780e-01 0.219 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 6.037780e-01 0.219 0 0
DAP12 interactions R-HSA-2172127 6.088037e-01 0.216 0 0
G1 Phase R-HSA-69236 6.088037e-01 0.216 0 0
Cyclin D associated events in G1 R-HSA-69231 6.088037e-01 0.216 0 0
EPHB-mediated forward signaling R-HSA-3928662 6.088037e-01 0.216 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 6.101526e-01 0.215 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.101526e-01 0.215 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 6.101526e-01 0.215 0 0
Clathrin-mediated endocytosis R-HSA-8856828 6.111305e-01 0.214 0 0
Platelet activation, signaling and aggregation R-HSA-76002 6.124521e-01 0.213 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.127191e-01 0.213 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 6.127191e-01 0.213 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.127191e-01 0.213 0 0
Regulation of signaling by CBL R-HSA-912631 6.127191e-01 0.213 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.127191e-01 0.213 0 0
Translesion Synthesis by POLH R-HSA-110320 6.127191e-01 0.213 0 0
Specification of the neural plate border R-HSA-9834899 6.127191e-01 0.213 0 0
Other interleukin signaling R-HSA-449836 6.127191e-01 0.213 0 0
The NLRP3 inflammasome R-HSA-844456 6.127191e-01 0.213 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.173919e-01 0.209 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 6.181930e-01 0.209 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 6.191176e-01 0.208 0 0
DAG and IP3 signaling R-HSA-1489509 6.191176e-01 0.208 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.205513e-01 0.207 0 0
Post-translational protein phosphorylation R-HSA-8957275 6.245467e-01 0.204 0 0
Signaling by FGFR R-HSA-190236 6.245467e-01 0.204 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 6.277393e-01 0.202 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 6.277393e-01 0.202 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 6.277393e-01 0.202 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 6.277393e-01 0.202 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 6.277393e-01 0.202 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 6.277393e-01 0.202 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.277393e-01 0.202 0 0
Negative regulation of MET activity R-HSA-6807004 6.277393e-01 0.202 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.277393e-01 0.202 0 0
Signal transduction by L1 R-HSA-445144 6.277393e-01 0.202 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 6.277393e-01 0.202 0 0
Signaling by FGFR in disease R-HSA-1226099 6.287546e-01 0.202 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 6.292208e-01 0.201 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 6.292208e-01 0.201 0 0
Diseases of DNA repair R-HSA-9675135 6.292208e-01 0.201 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 6.391143e-01 0.194 0 0
Synthesis of PC R-HSA-1483191 6.391143e-01 0.194 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.421779e-01 0.192 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.421779e-01 0.192 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 6.421779e-01 0.192 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 6.421779e-01 0.192 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 6.421779e-01 0.192 0 0
Selenocysteine synthesis R-HSA-2408557 6.454967e-01 0.190 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 6.454967e-01 0.190 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 6.560573e-01 0.183 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 6.560573e-01 0.183 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 6.560573e-01 0.183 0 0
Signaling by PDGFR in disease R-HSA-9671555 6.560573e-01 0.183 0 0
Ribavirin ADME R-HSA-9755088 6.560573e-01 0.183 0 0
Viral mRNA Translation R-HSA-192823 6.590281e-01 0.181 0 0
Nuclear Receptor transcription pathway R-HSA-383280 6.603327e-01 0.180 0 0
SLC-mediated transport of organic anions R-HSA-9955298 6.603327e-01 0.180 0 0
rRNA processing R-HSA-72312 6.636076e-01 0.178 0 0
Response of endothelial cells to shear stress R-HSA-9860931 6.656617e-01 0.177 0 0
PI3K Cascade R-HSA-109704 6.675477e-01 0.176 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.693991e-01 0.174 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 6.693991e-01 0.174 0 0
Signaling by MET R-HSA-6806834 6.753766e-01 0.170 0 0
Signaling by FGFR2 R-HSA-5654738 6.753766e-01 0.170 0 0
HSF1-dependent transactivation R-HSA-3371571 6.766149e-01 0.170 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 6.822242e-01 0.166 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 6.822242e-01 0.166 0 0
Interleukin-20 family signaling R-HSA-8854691 6.822242e-01 0.166 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 6.822242e-01 0.166 0 0
Platelet homeostasis R-HSA-418346 6.850299e-01 0.164 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 6.854798e-01 0.164 0 0
Neurexins and neuroligins R-HSA-6794361 6.854798e-01 0.164 0 0
Orc1 removal from chromatin R-HSA-68949 6.854798e-01 0.164 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 6.913077e-01 0.160 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 6.941444e-01 0.159 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 6.941444e-01 0.159 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 6.945525e-01 0.158 0 0
Complex III assembly R-HSA-9865881 6.945525e-01 0.158 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 6.945525e-01 0.158 0 0
Plasma lipoprotein assembly R-HSA-8963898 6.945525e-01 0.158 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 7.010760e-01 0.154 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 7.064033e-01 0.151 0 0
Laminin interactions R-HSA-3000157 7.064033e-01 0.151 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 7.108171e-01 0.148 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 7.108817e-01 0.148 0 0
G alpha (z) signalling events R-HSA-418597 7.108817e-01 0.148 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 7.108817e-01 0.148 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 7.177949e-01 0.144 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 7.177949e-01 0.144 0 0
Metalloprotease DUBs R-HSA-5689901 7.177949e-01 0.144 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 7.177949e-01 0.144 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 7.177949e-01 0.144 0 0
Cilium Assembly R-HSA-5617833 7.184081e-01 0.144 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 7.189591e-01 0.143 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 7.189591e-01 0.143 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 7.241340e-01 0.140 0 0
IRS-mediated signalling R-HSA-112399 7.268458e-01 0.139 0 0
Synthesis of PA R-HSA-1483166 7.268458e-01 0.139 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.272644e-01 0.138 0 0
Gene expression (Transcription) R-HSA-74160 7.272662e-01 0.138 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 7.287453e-01 0.137 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 7.287453e-01 0.137 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.287453e-01 0.137 0 0
Cristae formation R-HSA-8949613 7.287453e-01 0.137 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 7.287453e-01 0.137 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.287453e-01 0.137 0 0
Insulin processing R-HSA-264876 7.287453e-01 0.137 0 0
Ribosome-associated quality control R-HSA-9948299 7.322387e-01 0.135 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 7.327544e-01 0.135 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 7.345443e-01 0.134 0 0
Neddylation R-HSA-8951664 7.352084e-01 0.134 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 7.383202e-01 0.132 0 0
HIV elongation arrest and recovery R-HSA-167287 7.392713e-01 0.131 0 0
Pausing and recovery of HIV elongation R-HSA-167290 7.392713e-01 0.131 0 0
Telomere Extension By Telomerase R-HSA-171319 7.392713e-01 0.131 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.392713e-01 0.131 0 0
Insulin receptor recycling R-HSA-77387 7.392713e-01 0.131 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 7.392713e-01 0.131 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 7.392713e-01 0.131 0 0
Inflammasomes R-HSA-622312 7.392713e-01 0.131 0 0
Peroxisomal protein import R-HSA-9033241 7.420574e-01 0.130 0 0
ER-Phagosome pathway R-HSA-1236974 7.432052e-01 0.129 0 0
Macroautophagy R-HSA-1632852 7.471855e-01 0.127 0 0
tRNA Aminoacylation R-HSA-379724 7.493878e-01 0.125 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.493896e-01 0.125 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 7.493896e-01 0.125 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.493896e-01 0.125 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 7.493896e-01 0.125 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 7.553265e-01 0.122 0 0
PLC beta mediated events R-HSA-112043 7.565385e-01 0.121 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 7.591157e-01 0.120 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.591157e-01 0.120 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.591157e-01 0.120 0 0
Activation of BH3-only proteins R-HSA-114452 7.591157e-01 0.120 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 7.606443e-01 0.119 0 0
Heme signaling R-HSA-9707616 7.635123e-01 0.117 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 7.635123e-01 0.117 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 7.635123e-01 0.117 0 0
Signaling by PDGF R-HSA-186797 7.635123e-01 0.117 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 7.635123e-01 0.117 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 7.684650e-01 0.114 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.684650e-01 0.114 0 0
Downstream signal transduction R-HSA-186763 7.684650e-01 0.114 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 7.692388e-01 0.114 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 7.726396e-01 0.112 0 0
G0 and Early G1 R-HSA-1538133 7.774519e-01 0.109 0 0
Inwardly rectifying K+ channels R-HSA-1296065 7.774519e-01 0.109 0 0
Collagen formation R-HSA-1474290 7.781835e-01 0.109 0 0
Infectious disease R-HSA-5663205 7.824487e-01 0.107 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 7.836157e-01 0.106 0 0
S Phase R-HSA-69242 7.840031e-01 0.106 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 7.860905e-01 0.105 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 7.860905e-01 0.105 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 7.860905e-01 0.105 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 7.860905e-01 0.105 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 7.860905e-01 0.105 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 7.860905e-01 0.105 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 7.860905e-01 0.105 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 7.889377e-01 0.103 0 0
Potential therapeutics for SARS R-HSA-9679191 7.925295e-01 0.101 0 0
Resolution of D-Loop Structures R-HSA-5693537 7.943943e-01 0.100 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 7.943943e-01 0.100 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 7.943943e-01 0.100 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 7.943943e-01 0.100 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 7.943943e-01 0.100 0 0
Miscellaneous transport and binding events R-HSA-5223345 7.943943e-01 0.100 0 0
G-protein mediated events R-HSA-112040 7.958324e-01 0.099 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 7.966931e-01 0.099 0 0
Transcription of the HIV genome R-HSA-167172 8.018079e-01 0.096 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 8.018079e-01 0.096 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.023763e-01 0.096 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.023763e-01 0.096 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 8.023763e-01 0.096 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 8.023763e-01 0.096 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 8.023763e-01 0.096 0 0
G1/S Transition R-HSA-69206 8.028444e-01 0.095 0 0
Protein localization R-HSA-9609507 8.048233e-01 0.094 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.100489e-01 0.091 0 0
Post-translational protein modification R-HSA-597592 8.120702e-01 0.090 0 0
PPARA activates gene expression R-HSA-1989781 8.126941e-01 0.090 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 8.132949e-01 0.090 0 0
COPII-mediated vesicle transport R-HSA-204005 8.132949e-01 0.090 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 8.132949e-01 0.090 0 0
Autophagy R-HSA-9612973 8.165335e-01 0.088 0 0
RNA Polymerase III Transcription R-HSA-74158 8.174240e-01 0.088 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 8.174240e-01 0.088 0 0
Glycosphingolipid transport R-HSA-9845576 8.174240e-01 0.088 0 0
RUNX2 regulates bone development R-HSA-8941326 8.174240e-01 0.088 0 0
G1/S-Specific Transcription R-HSA-69205 8.174240e-01 0.088 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.174240e-01 0.088 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.188126e-01 0.087 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 8.188126e-01 0.087 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 8.203096e-01 0.086 0 0
PI Metabolism R-HSA-1483255 8.232139e-01 0.084 0 0
Cellular response to starvation R-HSA-9711097 8.240229e-01 0.084 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 8.241837e-01 0.084 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 8.241837e-01 0.084 0 0
Degradation of AXIN R-HSA-4641257 8.245132e-01 0.084 0 0
Degradation of DVL R-HSA-4641258 8.245132e-01 0.084 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 8.245132e-01 0.084 0 0
SLC-mediated transport of organic cations R-HSA-549127 8.245132e-01 0.084 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 8.245132e-01 0.084 0 0
Collagen chain trimerization R-HSA-8948216 8.245132e-01 0.084 0 0
Metabolism of folate and pterines R-HSA-196757 8.245132e-01 0.084 0 0
Vesicle-mediated transport R-HSA-5653656 8.259598e-01 0.083 0 0
Interferon gamma signaling R-HSA-877300 8.276740e-01 0.082 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 8.294115e-01 0.081 0 0
Ca2+ pathway R-HSA-4086398 8.294115e-01 0.081 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 8.313275e-01 0.080 0 0
Purine salvage R-HSA-74217 8.313275e-01 0.080 0 0
MET promotes cell motility R-HSA-8875878 8.313275e-01 0.080 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 8.313275e-01 0.080 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 8.313275e-01 0.080 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 8.320920e-01 0.080 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 8.344988e-01 0.079 0 0
Innate Immune System R-HSA-168249 8.352810e-01 0.078 0 0
Degradation of the extracellular matrix R-HSA-1474228 8.357184e-01 0.078 0 0
Stabilization of p53 R-HSA-69541 8.378777e-01 0.077 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 8.378777e-01 0.077 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 8.394488e-01 0.076 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 8.441739e-01 0.074 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 8.441739e-01 0.074 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 8.441739e-01 0.074 0 0
Aggrephagy R-HSA-9646399 8.441739e-01 0.074 0 0
HIV Transcription Elongation R-HSA-167169 8.441739e-01 0.074 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.441739e-01 0.074 0 0
Generation of second messenger molecules R-HSA-202433 8.441739e-01 0.074 0 0
SARS-CoV-1-host interactions R-HSA-9692914 8.446899e-01 0.073 0 0
Selenoamino acid metabolism R-HSA-2408522 8.450173e-01 0.073 0 0
Synthesis of DNA R-HSA-69239 8.487033e-01 0.071 0 0
Translation of Structural Proteins R-HSA-9694635 8.489485e-01 0.071 0 0
Antigen processing-Cross presentation R-HSA-1236975 8.526263e-01 0.069 0 0
PCP/CE pathway R-HSA-4086400 8.535041e-01 0.069 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 8.538451e-01 0.069 0 0
HIV Transcription Initiation R-HSA-167161 8.560432e-01 0.068 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 8.560432e-01 0.068 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 8.560432e-01 0.068 0 0
Activation of GABAB receptors R-HSA-991365 8.616349e-01 0.065 0 0
GABA B receptor activation R-HSA-977444 8.616349e-01 0.065 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 8.670098e-01 0.062 0 0
TBC/RABGAPs R-HSA-8854214 8.670098e-01 0.062 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.674435e-01 0.062 0 0
Neuronal System R-HSA-112316 8.695366e-01 0.061 0 0
Transmission across Chemical Synapses R-HSA-112315 8.700628e-01 0.060 0 0
Surfactant metabolism R-HSA-5683826 8.721761e-01 0.059 0 0
Amine ligand-binding receptors R-HSA-375280 8.721761e-01 0.059 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 8.721761e-01 0.059 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 8.744555e-01 0.058 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 8.771421e-01 0.057 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 8.771421e-01 0.057 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 8.771421e-01 0.057 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.771421e-01 0.057 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 8.783000e-01 0.056 0 0
SARS-CoV-1 Infection R-HSA-9678108 8.808179e-01 0.055 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 8.809325e-01 0.055 0 0
Keratinization R-HSA-6805567 8.814786e-01 0.055 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 8.819154e-01 0.055 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.819154e-01 0.055 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.819154e-01 0.055 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 8.856651e-01 0.053 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 8.865036e-01 0.052 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 8.865036e-01 0.052 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 8.865036e-01 0.052 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 8.878151e-01 0.052 0 0
Rab regulation of trafficking R-HSA-9007101 8.902342e-01 0.050 0 0
NGF-stimulated transcription R-HSA-9031628 8.909138e-01 0.050 0 0
Co-stimulation by CD28 R-HSA-389356 8.909138e-01 0.050 0 0
Chaperonin-mediated protein folding R-HSA-390466 8.926157e-01 0.049 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 8.951528e-01 0.048 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 8.951528e-01 0.048 0 0
Gap junction trafficking and regulation R-HSA-157858 8.951528e-01 0.048 0 0
Azathioprine ADME R-HSA-9748787 8.992274e-01 0.046 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.031439e-01 0.044 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.031439e-01 0.044 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 9.069083e-01 0.042 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 9.069083e-01 0.042 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 9.105267e-01 0.041 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 9.105267e-01 0.041 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.105267e-01 0.041 0 0
Protein folding R-HSA-391251 9.111806e-01 0.040 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.111806e-01 0.040 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 9.120971e-01 0.040 0 0
FCGR activation R-HSA-2029481 9.139662e-01 0.039 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.140047e-01 0.039 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.167153e-01 0.038 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.168166e-01 0.038 0 0
Paracetamol ADME R-HSA-9753281 9.173477e-01 0.037 0 0
Organelle biogenesis and maintenance R-HSA-1852241 9.205051e-01 0.036 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 9.205609e-01 0.036 0 0
Dectin-2 family R-HSA-5621480 9.236494e-01 0.034 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.243092e-01 0.034 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.266179e-01 0.033 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 9.267055e-01 0.033 0 0
RNA Polymerase II Transcription R-HSA-73857 9.284868e-01 0.032 0 0
Extension of Telomeres R-HSA-180786 9.294713e-01 0.032 0 0
Phospholipid metabolism R-HSA-1483257 9.300021e-01 0.032 0 0
FOXO-mediated transcription R-HSA-9614085 9.312851e-01 0.031 0 0
Circadian clock R-HSA-9909396 9.316394e-01 0.031 0 0
GABA receptor activation R-HSA-977443 9.322139e-01 0.030 0 0
Nucleotide salvage R-HSA-8956321 9.348499e-01 0.029 0 0
Aquaporin-mediated transport R-HSA-445717 9.348499e-01 0.029 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.348499e-01 0.029 0 0
Extracellular matrix organization R-HSA-1474244 9.357161e-01 0.029 0 0
Cellular response to chemical stress R-HSA-9711123 9.371928e-01 0.028 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.373836e-01 0.028 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.379488e-01 0.028 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 9.398190e-01 0.027 0 0
Opioid Signalling R-HSA-111885 9.415785e-01 0.026 0 0
Translation R-HSA-72766 9.418335e-01 0.026 0 0
G alpha (s) signalling events R-HSA-418555 9.420482e-01 0.026 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.421597e-01 0.026 0 0
Generic Transcription Pathway R-HSA-212436 9.430917e-01 0.025 0 0
Cellular response to hypoxia R-HSA-1234174 9.444096e-01 0.025 0 0
Nucleotide Excision Repair R-HSA-5696398 9.452711e-01 0.024 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.465721e-01 0.024 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 9.486505e-01 0.023 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.506483e-01 0.022 0 0
TCR signaling R-HSA-202403 9.535549e-01 0.021 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 9.544139e-01 0.020 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.561878e-01 0.019 0 0
Purine catabolism R-HSA-74259 9.578927e-01 0.019 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 9.578927e-01 0.019 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.626202e-01 0.017 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.626202e-01 0.017 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 9.626202e-01 0.017 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.631640e-01 0.016 0 0
UCH proteinases R-HSA-5689603 9.640751e-01 0.016 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.654736e-01 0.015 0 0
Mitochondrial biogenesis R-HSA-1592230 9.655386e-01 0.015 0 0
Integrin cell surface interactions R-HSA-216083 9.668176e-01 0.015 0 0
Developmental Cell Lineages R-HSA-9734767 9.673681e-01 0.014 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 9.677657e-01 0.014 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 9.698540e-01 0.013 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.705444e-01 0.013 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.727937e-01 0.012 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.738532e-01 0.012 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.757063e-01 0.011 0 0
Pyruvate metabolism R-HSA-70268 9.776949e-01 0.010 0 0
Downstream TCR signaling R-HSA-202424 9.802015e-01 0.009 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.810318e-01 0.008 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.814835e-01 0.008 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.814835e-01 0.008 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.824268e-01 0.008 0 0
Mitochondrial translation elongation R-HSA-5389840 9.855945e-01 0.006 0 0
Potassium Channels R-HSA-1296071 9.855945e-01 0.006 0 0
Mitochondrial translation initiation R-HSA-5368286 9.866958e-01 0.006 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.872144e-01 0.006 0 0
G alpha (q) signalling events R-HSA-416476 9.875178e-01 0.005 0 0
ABC-family proteins mediated transport R-HSA-382556 9.877129e-01 0.005 0 0
Hedgehog 'off' state R-HSA-5610787 9.877129e-01 0.005 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.890949e-01 0.005 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.911289e-01 0.004 0 0
Mitochondrial translation termination R-HSA-5419276 9.917458e-01 0.004 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.920678e-01 0.003 0 0
Antimicrobial peptides R-HSA-6803157 9.923773e-01 0.003 0 0
Peptide hormone metabolism R-HSA-2980736 9.944564e-01 0.002 0 0
Metabolism of proteins R-HSA-392499 9.948489e-01 0.002 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.956347e-01 0.002 0 0
Transport of small molecules R-HSA-382551 9.956725e-01 0.002 0 0
Respiratory electron transport R-HSA-611105 9.964655e-01 0.002 0 0
Nucleotide catabolism R-HSA-8956319 9.966972e-01 0.001 0 0
Sensory perception of taste R-HSA-9717189 9.970694e-01 0.001 0 0
Integration of energy metabolism R-HSA-163685 9.976928e-01 0.001 0 0
Mitochondrial translation R-HSA-5368287 9.978697e-01 0.001 0 0
Signaling by Hedgehog R-HSA-5358351 9.978697e-01 0.001 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.983887e-01 0.001 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.986801e-01 0.001 0 0
Gastrulation R-HSA-9758941 9.986801e-01 0.001 0 0
Arachidonate metabolism R-HSA-2142753 9.988291e-01 0.001 0 0
Drug ADME R-HSA-9748784 9.991871e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.994548e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.996780e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.996868e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.997109e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.997386e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.997621e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.998263e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.998970e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999335e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999523e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999625e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999838e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999931e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999987e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999993e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999996e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999997e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999998e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999998e-01 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.110223e-16 15.955 0 0
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Cell Cycle, Mitotic R-HSA-69278 1.110223e-16 15.955 0 0
Cell Cycle R-HSA-1640170 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Mitotic Prophase R-HSA-68875 3.330669e-16 15.477 0 0
HCMV Early Events R-HSA-9609690 4.440892e-16 15.353 0 0
Post NMDA receptor activation events R-HSA-438064 3.663736e-15 14.436 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 7.882583e-15 14.103 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 8.881784e-15 14.051 0 0
Cell-Cell communication R-HSA-1500931 1.032507e-14 13.986 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.398881e-14 13.854 0 0
HSF1-dependent transactivation R-HSA-3371571 1.831868e-14 13.737 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 3.996803e-14 13.398 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 5.762057e-14 13.239 0 0
Transport of connexons to the plasma membrane R-HSA-190872 7.227552e-14 13.141 0 0
HCMV Infection R-HSA-9609646 8.471002e-14 13.072 0 0
Interferon Signaling R-HSA-913531 8.493206e-14 13.071 0 0
Cell junction organization R-HSA-446728 8.160139e-14 13.088 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.320055e-13 12.879 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.968425e-13 12.706 0 0
PKR-mediated signaling R-HSA-9833482 3.704814e-13 12.431 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 4.054534e-13 12.392 0 0
L1CAM interactions R-HSA-373760 4.074519e-13 12.390 0 0
Recycling pathway of L1 R-HSA-437239 6.636913e-13 12.178 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.558198e-12 11.807 0 0
Viral Infection Pathways R-HSA-9824446 2.079337e-12 11.682 0 0
Gap junction trafficking R-HSA-190828 2.944311e-12 11.531 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 3.744227e-12 11.427 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 3.923861e-12 11.406 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 5.434209e-12 11.265 0 0
Influenza Infection R-HSA-168255 6.294631e-12 11.201 0 0
Aggrephagy R-HSA-9646399 7.110090e-12 11.148 0 0
Cytokine Signaling in Immune system R-HSA-1280215 8.231082e-12 11.085 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.248757e-11 10.904 0 0
Gap junction trafficking and regulation R-HSA-157858 1.210965e-11 10.917 0 0
Signal Transduction R-HSA-162582 1.285194e-11 10.891 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.429334e-11 10.845 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.780953e-11 10.749 0 0
Gene Silencing by RNA R-HSA-211000 1.810596e-11 10.742 0 0
Mitotic Anaphase R-HSA-68882 2.070744e-11 10.684 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.301970e-11 10.638 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.320988e-11 10.634 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 2.504474e-11 10.601 0 0
Mitotic Prometaphase R-HSA-68877 3.235567e-11 10.490 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 3.411504e-11 10.467 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.556155e-11 10.449 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 4.346512e-11 10.362 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 5.341294e-11 10.272 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 7.369361e-11 10.133 0 0
Attenuation phase R-HSA-3371568 7.772916e-11 10.109 0 0
Developmental Biology R-HSA-1266738 7.891920e-11 10.103 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.035277e-10 9.985 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.045375e-10 9.981 0 0
Separation of Sister Chromatids R-HSA-2467813 1.143766e-10 9.942 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.148935e-10 9.940 0 0
Gap junction assembly R-HSA-190861 1.400262e-10 9.854 0 0
Metabolism of RNA R-HSA-8953854 2.080507e-10 9.682 0 0
DNA methylation R-HSA-5334118 2.329658e-10 9.633 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.946030e-10 9.531 0 0
Protein folding R-HSA-391251 2.946030e-10 9.531 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.610160e-10 9.442 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.610160e-10 9.442 0 0
Cap-dependent Translation Initiation R-HSA-72737 5.751816e-10 9.240 0 0
Eukaryotic Translation Initiation R-HSA-72613 5.751816e-10 9.240 0 0
ESR-mediated signaling R-HSA-8939211 6.985561e-10 9.156 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 7.957255e-10 9.099 0 0
Selective autophagy R-HSA-9663891 8.330484e-10 9.079 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 8.469362e-10 9.072 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 9.481373e-10 9.023 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 1.137502e-09 8.944 0 0
G2/M Transition R-HSA-69275 1.443186e-09 8.841 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.531127e-09 8.815 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.633001e-09 8.787 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.633001e-09 8.787 0 0
Meiotic recombination R-HSA-912446 1.658920e-09 8.780 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.768330e-09 8.752 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 2.073233e-09 8.683 0 0
Cell-cell junction organization R-HSA-421270 2.393969e-09 8.621 0 0
PRC2 methylates histones and DNA R-HSA-212300 2.683659e-09 8.571 0 0
HSF1 activation R-HSA-3371511 2.683659e-09 8.571 0 0
Cellular Senescence R-HSA-2559583 3.423789e-09 8.465 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 3.515058e-09 8.454 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 3.812797e-09 8.419 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 3.888538e-09 8.410 0 0
Signaling by RAS mutants R-HSA-6802949 4.533972e-09 8.344 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 4.533972e-09 8.344 0 0
Signaling downstream of RAS mutants R-HSA-9649948 4.533972e-09 8.344 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 4.533972e-09 8.344 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 4.478186e-09 8.349 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 5.693987e-09 8.245 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 6.415641e-09 8.193 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 7.270512e-09 8.138 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 7.595560e-09 8.119 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 7.736161e-09 8.111 0 0
Adherens junctions interactions R-HSA-418990 7.975599e-09 8.098 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 9.509386e-09 8.022 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.701527e-09 8.013 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.706777e-09 8.013 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.073307e-08 7.969 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 1.073307e-08 7.969 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.232171e-08 7.909 0 0
Infectious disease R-HSA-5663205 1.486621e-08 7.828 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 1.487536e-08 7.828 0 0
Packaging Of Telomere Ends R-HSA-171306 1.679361e-08 7.775 0 0
Meiosis R-HSA-1500620 1.736114e-08 7.760 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.783480e-08 7.749 0 0
Defective pyroptosis R-HSA-9710421 1.956025e-08 7.709 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 2.416982e-08 7.617 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.470390e-08 7.607 0 0
HDACs deacetylate histones R-HSA-3214815 3.020880e-08 7.520 0 0
Peptide chain elongation R-HSA-156902 3.159883e-08 7.500 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 3.020880e-08 7.520 0 0
Signaling by ROBO receptors R-HSA-376176 2.986231e-08 7.525 0 0
Cilium Assembly R-HSA-5617833 3.704351e-08 7.431 0 0
Cell Cycle Checkpoints R-HSA-69620 5.560680e-08 7.255 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 5.708666e-08 7.243 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 6.280538e-08 7.202 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 6.612432e-08 7.180 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 6.867442e-08 7.163 0 0
Assembly of the pre-replicative complex R-HSA-68867 7.355026e-08 7.133 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 7.384808e-08 7.132 0 0
Kinesins R-HSA-983189 7.610717e-08 7.119 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.023743e-07 6.990 0 0
Autophagy R-HSA-9612973 9.614085e-08 7.017 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.077598e-07 6.968 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.396376e-07 6.855 0 0
Telomere Maintenance R-HSA-157579 1.422587e-07 6.847 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 1.453568e-07 6.838 0 0
Chromosome Maintenance R-HSA-73886 1.459260e-07 6.836 0 0
Meiotic synapsis R-HSA-1221632 1.501572e-07 6.823 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.602932e-07 6.795 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 1.987549e-07 6.702 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 1.987549e-07 6.702 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 2.088874e-07 6.680 0 0
Glycolysis R-HSA-70171 2.076301e-07 6.683 0 0
RNA Polymerase I Transcription R-HSA-73864 2.152426e-07 6.667 0 0
Nucleosome assembly R-HSA-774815 2.392851e-07 6.621 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 2.392851e-07 6.621 0 0
Regulation of endogenous retroelements R-HSA-9842860 2.653103e-07 6.576 0 0
Ribosome-associated quality control R-HSA-9948299 2.677895e-07 6.572 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.866963e-07 6.543 0 0
Cleavage of the damaged purine R-HSA-110331 2.900350e-07 6.538 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 2.972286e-07 6.527 0 0
Macroautophagy R-HSA-1632852 3.598123e-07 6.444 0 0
Depurination R-HSA-73927 3.608825e-07 6.443 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 3.618582e-07 6.441 0 0
Intraflagellar transport R-HSA-5620924 4.249600e-07 6.372 0 0
Immune System R-HSA-168256 4.423087e-07 6.354 0 0
Disease R-HSA-1643685 5.173240e-07 6.286 0 0
Formation of a pool of free 40S subunits R-HSA-72689 5.684910e-07 6.245 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 5.849651e-07 6.233 0 0
MAPK family signaling cascades R-HSA-5683057 5.961699e-07 6.225 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.416726e-07 6.193 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 7.860783e-07 6.105 0 0
HATs acetylate histones R-HSA-3214847 9.151510e-07 6.039 0 0
Diseases of programmed cell death R-HSA-9645723 9.508393e-07 6.022 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.965973e-07 6.001 0 0
Depyrimidination R-HSA-73928 9.965973e-07 6.001 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.060345e-06 5.975 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.094122e-06 5.961 0 0
DNA Replication R-HSA-69306 1.194748e-06 5.923 0 0
Translation initiation complex formation R-HSA-72649 1.212882e-06 5.916 0 0
Transmission across Chemical Synapses R-HSA-112315 1.263248e-06 5.899 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.289768e-06 5.889 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 1.376165e-06 5.861 0 0
DNA Double Strand Break Response R-HSA-5693606 1.470100e-06 5.833 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.797387e-06 5.745 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.797387e-06 5.745 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.696639e-06 5.770 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.611112e-06 5.793 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.791735e-06 5.747 0 0
Glucose metabolism R-HSA-70326 1.935491e-06 5.713 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.961641e-06 5.707 0 0
Reproduction R-HSA-1474165 1.975235e-06 5.704 0 0
Apoptotic execution phase R-HSA-75153 2.072436e-06 5.684 0 0
Homology Directed Repair R-HSA-5693538 2.139268e-06 5.670 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 2.240425e-06 5.650 0 0
Translation R-HSA-72766 2.287801e-06 5.641 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 2.319486e-06 5.635 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 2.474205e-06 5.607 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 2.478179e-06 5.606 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 2.609420e-06 5.583 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.664370e-06 5.574 0 0
Eukaryotic Translation Termination R-HSA-72764 2.770597e-06 5.557 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 2.771748e-06 5.557 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 3.472330e-06 5.459 0 0
MHC class II antigen presentation R-HSA-2132295 3.478723e-06 5.459 0 0
G2/M DNA damage checkpoint R-HSA-69473 3.831820e-06 5.417 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.999765e-06 5.398 0 0
RAF/MAP kinase cascade R-HSA-5673001 4.363267e-06 5.360 0 0
DNA Double-Strand Break Repair R-HSA-5693532 4.537864e-06 5.343 0 0
Selenocysteine synthesis R-HSA-2408557 5.316427e-06 5.274 0 0
G2/M Checkpoints R-HSA-69481 5.530446e-06 5.257 0 0
MAP2K and MAPK activation R-HSA-5674135 5.904071e-06 5.229 0 0
Viral mRNA Translation R-HSA-192823 6.542165e-06 5.184 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 5.754650e-06 5.240 0 0
Base Excision Repair R-HSA-73884 5.956545e-06 5.225 0 0
Signaling by NOTCH R-HSA-157118 6.082501e-06 5.216 0 0
Ub-specific processing proteases R-HSA-5689880 6.548442e-06 5.184 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 6.660998e-06 5.176 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 6.736795e-06 5.172 0 0
Metabolism of proteins R-HSA-392499 6.906523e-06 5.161 0 0
Signaling by WNT R-HSA-195721 7.267058e-06 5.139 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 7.536620e-06 5.123 0 0
mRNA Splicing - Major Pathway R-HSA-72163 8.794640e-06 5.056 0 0
Amyloid fiber formation R-HSA-977225 9.083639e-06 5.042 0 0
Long-term potentiation R-HSA-9620244 9.638222e-06 5.016 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 9.722804e-06 5.012 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.009375e-05 4.996 0 0
Regulation of CDH1 Function R-HSA-9764561 1.163392e-05 4.934 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 1.310107e-05 4.883 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.348949e-05 4.870 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.402885e-05 4.853 0 0
Deubiquitination R-HSA-5688426 1.503969e-05 4.823 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.540745e-05 4.812 0 0
Signaling by Hedgehog R-HSA-5358351 1.678863e-05 4.775 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.795362e-05 4.746 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 1.812224e-05 4.742 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 1.812224e-05 4.742 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 1.812224e-05 4.742 0 0
Signaling by VEGF R-HSA-194138 1.812224e-05 4.742 0 0
mRNA Splicing R-HSA-72172 1.834256e-05 4.737 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.893645e-05 4.723 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.274972e-05 4.643 0 0
Platelet degranulation R-HSA-114608 2.145594e-05 4.668 0 0
HCMV Late Events R-HSA-9610379 2.209223e-05 4.656 0 0
Hemostasis R-HSA-109582 1.937410e-05 4.713 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.199105e-05 4.658 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 2.199105e-05 4.658 0 0
Hedgehog 'off' state R-HSA-5610787 2.089224e-05 4.680 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 2.073120e-05 4.683 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.361062e-05 4.627 0 0
Semaphorin interactions R-HSA-373755 2.589485e-05 4.587 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.773698e-05 4.557 0 0
Muscle contraction R-HSA-397014 3.032068e-05 4.518 0 0
ER to Golgi Anterograde Transport R-HSA-199977 3.632559e-05 4.440 0 0
Selenoamino acid metabolism R-HSA-2408522 3.649294e-05 4.438 0 0
SARS-CoV-1-host interactions R-HSA-9692914 4.018404e-05 4.396 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 5.404241e-05 4.267 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 5.846045e-05 4.233 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 6.060800e-05 4.217 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 6.488586e-05 4.188 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 6.693449e-05 4.174 0 0
RAF activation R-HSA-5673000 6.832139e-05 4.165 0 0
Nuclear import of Rev protein R-HSA-180746 6.832139e-05 4.165 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 7.256771e-05 4.139 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 7.414171e-05 4.130 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 7.448722e-05 4.128 0 0
Cellular response to starvation R-HSA-9711097 7.903404e-05 4.102 0 0
Signaling by ERBB2 R-HSA-1227986 9.132995e-05 4.039 0 0
rRNA processing R-HSA-72312 9.587785e-05 4.018 0 0
Gluconeogenesis R-HSA-70263 1.055581e-04 3.977 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.153801e-04 3.938 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.186884e-04 3.926 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.292167e-04 3.889 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.292167e-04 3.889 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.292167e-04 3.889 0 0
Signaling by PTK6 R-HSA-8848021 1.292167e-04 3.889 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.493169e-04 3.826 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 1.664615e-04 3.779 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 1.725025e-04 3.763 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.755989e-04 3.755 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.795946e-04 3.746 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.813942e-04 3.741 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.930328e-04 3.714 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 1.972783e-04 3.705 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 3.309184e-04 3.480 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.789554e-04 3.554 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.182885e-04 3.497 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.789554e-04 3.554 0 0
Platelet activation, signaling and aggregation R-HSA-76002 2.922589e-04 3.534 0 0
Neuronal System R-HSA-112316 3.426600e-04 3.465 0 0
Co-inhibition by PD-1 R-HSA-389948 3.478463e-04 3.459 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 3.640619e-04 3.439 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.697735e-04 3.432 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 4.039336e-04 3.394 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 4.224311e-04 3.374 0 0
Protein methylation R-HSA-8876725 4.224311e-04 3.374 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.315770e-04 3.365 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.315770e-04 3.365 0 0
Centrosome maturation R-HSA-380287 4.392035e-04 3.357 0 0
Protein ubiquitination R-HSA-8852135 4.392035e-04 3.357 0 0
Adaptive Immune System R-HSA-1280218 4.426290e-04 3.354 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 4.530470e-04 3.344 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 4.926890e-04 3.307 0 0
Neutrophil degranulation R-HSA-6798695 4.992692e-04 3.302 0 0
SARS-CoV-2-host interactions R-HSA-9705683 5.611724e-04 3.251 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 5.652907e-04 3.248 0 0
Host Interactions of HIV factors R-HSA-162909 6.668130e-04 3.176 0 0
SARS-CoV-1 Infection R-HSA-9678108 7.012565e-04 3.154 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 7.359151e-04 3.133 0 0
Chromatin modifying enzymes R-HSA-3247509 7.423868e-04 3.129 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 7.999844e-04 3.097 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 8.352716e-04 3.078 0 0
Folding of actin by CCT/TriC R-HSA-390450 9.057663e-04 3.043 0 0
Apoptosis R-HSA-109581 9.188082e-04 3.037 0 0
Epigenetic regulation of gene expression R-HSA-212165 9.433679e-04 3.025 0 0
Smooth Muscle Contraction R-HSA-445355 9.433712e-04 3.025 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 9.449235e-04 3.025 0 0
Chaperone Mediated Autophagy R-HSA-9613829 9.890913e-04 3.005 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 1.028869e-03 2.988 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.065602e-03 2.972 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.231791e-03 2.909 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.413656e-03 2.850 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.413656e-03 2.850 0 0
Trafficking of AMPA receptors R-HSA-399719 1.413656e-03 2.850 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 1.413656e-03 2.850 0 0
Nephrin family interactions R-HSA-373753 1.424484e-03 2.846 0 0
Signal transduction by L1 R-HSA-445144 1.424484e-03 2.846 0 0
Chromatin organization R-HSA-4839726 1.428839e-03 2.845 0 0
Post-translational protein modification R-HSA-597592 1.603800e-03 2.795 0 0
DNA Repair R-HSA-73894 1.627478e-03 2.788 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.838088e-03 2.736 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.838088e-03 2.736 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.838088e-03 2.736 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.861676e-03 2.730 0 0
DAG and IP3 signaling R-HSA-1489509 1.861676e-03 2.730 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.927360e-03 2.715 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.986893e-03 2.702 0 0
EPH-Ephrin signaling R-HSA-2682334 2.025066e-03 2.694 0 0
Viral Messenger RNA Synthesis R-HSA-168325 2.029073e-03 2.693 0 0
Striated Muscle Contraction R-HSA-390522 2.083399e-03 2.681 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 2.083399e-03 2.681 0 0
mTORC1-mediated signalling R-HSA-166208 2.321983e-03 2.634 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 2.333760e-03 2.632 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.373714e-03 2.625 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.928741e-03 2.533 0 0
Late Phase of HIV Life Cycle R-HSA-162599 2.436883e-03 2.613 0 0
HIV Infection R-HSA-162906 3.219434e-03 2.492 0 0
Calmodulin induced events R-HSA-111933 2.968736e-03 2.527 0 0
CaM pathway R-HSA-111997 2.968736e-03 2.527 0 0
Syndecan interactions R-HSA-3000170 2.696384e-03 2.569 0 0
Programmed Cell Death R-HSA-5357801 3.078726e-03 2.512 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 3.318500e-03 2.479 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 3.555073e-03 2.449 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.668795e-03 2.435 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 3.877910e-03 2.411 0 0
Amplification of signal from the kinetochores R-HSA-141424 3.877910e-03 2.411 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 4.347605e-03 2.362 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 4.347605e-03 2.362 0 0
Manipulation of host energy metabolism R-HSA-9636667 4.360100e-03 2.361 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.375558e-03 2.359 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 4.552551e-03 2.342 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 4.555941e-03 2.341 0 0
Regulation of mitotic cell cycle R-HSA-453276 4.555941e-03 2.341 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 4.638205e-03 2.334 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 4.638205e-03 2.334 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.638205e-03 2.334 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 5.030505e-03 2.298 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 5.030505e-03 2.298 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 5.046707e-03 2.297 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 5.046707e-03 2.297 0 0
HIV Life Cycle R-HSA-162587 5.103544e-03 2.292 0 0
HIV elongation arrest and recovery R-HSA-167287 5.247428e-03 2.280 0 0
Pausing and recovery of HIV elongation R-HSA-167290 5.247428e-03 2.280 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 5.268891e-03 2.278 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 5.651786e-03 2.248 0 0
Formation of annular gap junctions R-HSA-196025 5.651786e-03 2.248 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 5.651786e-03 2.248 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 5.929104e-03 2.227 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 6.095388e-03 2.215 0 0
Ca-dependent events R-HSA-111996 6.095388e-03 2.215 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 6.908597e-03 2.161 0 0
Gap junction degradation R-HSA-190873 7.166813e-03 2.145 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 7.588959e-03 2.120 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 7.588959e-03 2.120 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 7.588959e-03 2.120 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 7.588959e-03 2.120 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 7.588959e-03 2.120 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 7.588959e-03 2.120 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 7.588959e-03 2.120 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 7.588959e-03 2.120 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 7.588959e-03 2.120 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 7.588959e-03 2.120 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 7.588959e-03 2.120 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 7.588959e-03 2.120 0 0
tRNA processing in the nucleus R-HSA-6784531 8.250628e-03 2.084 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 8.900293e-03 2.051 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 9.159741e-03 2.038 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.576890e-03 2.019 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 1.013193e-02 1.994 0 0
Basigin interactions R-HSA-210991 1.047104e-02 1.980 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 1.147767e-02 1.940 0 0
Developmental Cell Lineages R-HSA-9734767 1.157244e-02 1.937 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.187910e-02 1.925 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.187910e-02 1.925 0 0
SARS-CoV Infections R-HSA-9679506 1.304190e-02 1.885 0 0
FGFR2 alternative splicing R-HSA-6803529 1.340311e-02 1.873 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.340311e-02 1.873 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 1.420409e-02 1.848 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 1.504332e-02 1.823 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.504932e-02 1.822 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.546730e-02 1.811 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.605673e-02 1.794 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.628716e-02 1.788 0 0
Signaling by ALK in cancer R-HSA-9700206 1.628716e-02 1.788 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.637026e-02 1.786 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 1.637026e-02 1.786 0 0
MTF1 activates gene expression R-HSA-5660489 1.637026e-02 1.786 0 0
Deadenylation of mRNA R-HSA-429947 1.681080e-02 1.774 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 1.747395e-02 1.758 0 0
Signaling by ERBB4 R-HSA-1236394 1.811737e-02 1.742 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.812439e-02 1.742 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.812439e-02 1.742 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 1.812439e-02 1.742 0 0
Membrane Trafficking R-HSA-199991 1.823265e-02 1.739 0 0
Ion homeostasis R-HSA-5578775 1.854852e-02 1.732 0 0
HDMs demethylate histones R-HSA-3214842 1.869972e-02 1.728 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.869972e-02 1.728 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.896690e-02 1.722 0 0
HIV Transcription Elongation R-HSA-167169 1.896690e-02 1.722 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 1.896690e-02 1.722 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 1.896690e-02 1.722 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.181887e-02 1.661 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.790771e-02 1.554 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 2.285885e-02 1.641 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 3.007641e-02 1.522 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 2.768283e-02 1.558 0 0
p38MAPK events R-HSA-171007 2.415207e-02 1.617 0 0
Mitochondrial protein import R-HSA-1268020 2.715092e-02 1.566 0 0
RMTs methylate histone arginines R-HSA-3214858 2.768283e-02 1.558 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.752320e-02 1.560 0 0
Myogenesis R-HSA-525793 2.071508e-02 1.684 0 0
Interaction between L1 and Ankyrins R-HSA-445095 2.285885e-02 1.641 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 2.513273e-02 1.600 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 2.715092e-02 1.566 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 2.880308e-02 1.541 0 0
Negative regulation of MAPK pathway R-HSA-5675221 2.219881e-02 1.654 0 0
MTOR signalling R-HSA-165159 2.394069e-02 1.621 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 2.841678e-02 1.546 0 0
snRNP Assembly R-HSA-191859 2.257468e-02 1.646 0 0
Metabolism of non-coding RNA R-HSA-194441 2.257468e-02 1.646 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 2.753818e-02 1.560 0 0
PLC beta mediated events R-HSA-112043 2.556274e-02 1.592 0 0
PCP/CE pathway R-HSA-4086400 2.273276e-02 1.643 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 2.880308e-02 1.541 0 0
FLT3 Signaling R-HSA-9607240 2.054135e-02 1.687 0 0
Interleukin-12 signaling R-HSA-9020591 2.033390e-02 1.692 0 0
Signaling by Interleukins R-HSA-449147 3.056239e-02 1.515 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 3.165700e-02 1.500 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 3.177706e-02 1.498 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 3.230266e-02 1.491 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 3.395865e-02 1.469 0 0
Opioid Signalling R-HSA-111885 3.465941e-02 1.460 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 3.497534e-02 1.456 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 3.497534e-02 1.456 0 0
Signaling by Hippo R-HSA-2028269 3.497534e-02 1.456 0 0
Diseases of mitotic cell cycle R-HSA-9675126 3.555474e-02 1.449 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 3.555474e-02 1.449 0 0
G-protein mediated events R-HSA-112040 3.606765e-02 1.443 0 0
Interleukin-12 family signaling R-HSA-447115 3.767084e-02 1.424 0 0
Nucleotide Excision Repair R-HSA-5696398 3.770950e-02 1.424 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 3.859482e-02 1.413 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 3.859482e-02 1.413 0 0
SOS-mediated signalling R-HSA-112412 4.182500e-02 1.379 0 0
Disinhibition of SNARE formation R-HSA-114516 4.182500e-02 1.379 0 0
CHL1 interactions R-HSA-447041 4.182500e-02 1.379 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 4.182500e-02 1.379 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 4.222419e-02 1.374 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 4.335959e-02 1.363 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 4.335959e-02 1.363 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 4.359911e-02 1.361 0 0
Hedgehog ligand biogenesis R-HSA-5358346 4.359911e-02 1.361 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 4.431628e-02 1.353 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 4.478411e-02 1.349 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 4.624047e-02 1.335 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.624047e-02 1.335 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 4.667415e-02 1.331 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 4.667415e-02 1.331 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 4.789363e-02 1.320 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 4.813072e-02 1.318 0 0
Signalling to ERKs R-HSA-187687 4.813072e-02 1.318 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.897507e-02 1.310 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.897507e-02 1.310 0 0
Type I hemidesmosome assembly R-HSA-446107 4.956844e-02 1.305 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 4.956844e-02 1.305 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 4.956844e-02 1.305 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 5.180310e-02 1.286 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 5.265051e-02 1.279 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 5.265051e-02 1.279 0 0
Signalling to RAS R-HSA-167044 5.265051e-02 1.279 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 5.472465e-02 1.262 0 0
UCH proteinases R-HSA-5689603 5.641732e-02 1.249 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 5.762582e-02 1.239 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 5.762582e-02 1.239 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 5.773973e-02 1.239 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 5.773973e-02 1.239 0 0
Lipophagy R-HSA-9613354 5.778191e-02 1.238 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 5.778191e-02 1.238 0 0
ALK mutants bind TKIs R-HSA-9700645 5.778191e-02 1.238 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 5.778191e-02 1.238 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 5.778191e-02 1.238 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 5.778191e-02 1.238 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 5.897545e-02 1.229 0 0
Interferon alpha/beta signaling R-HSA-909733 5.978894e-02 1.223 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 6.015687e-02 1.221 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 6.084823e-02 1.216 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 6.171430e-02 1.210 0 0
TICAM1 deficiency - HSE R-HSA-5602566 6.231371e-02 1.205 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 6.231371e-02 1.205 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 6.231371e-02 1.205 0 0
Inhibition of PKR R-HSA-169131 6.231371e-02 1.205 0 0
Pentose phosphate pathway R-HSA-71336 6.285599e-02 1.202 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 6.419505e-02 1.192 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 6.642800e-02 1.178 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 6.642800e-02 1.178 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 6.821227e-02 1.166 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 6.821227e-02 1.166 0 0
RAB geranylgeranylation R-HSA-8873719 7.073191e-02 1.150 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 7.100882e-02 1.149 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 7.262950e-02 1.139 0 0
MAP kinase activation R-HSA-450294 7.421129e-02 1.130 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.547121e-02 1.122 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 7.931129e-02 1.101 0 0
Tight junction interactions R-HSA-420029 7.961073e-02 1.099 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 7.961073e-02 1.099 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 7.961073e-02 1.099 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 7.961073e-02 1.099 0 0
Interleukin-7 signaling R-HSA-1266695 7.961073e-02 1.099 0 0
Response of endothelial cells to shear stress R-HSA-9860931 8.102210e-02 1.091 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 8.419503e-02 1.075 0 0
Response of Mtb to phagocytosis R-HSA-9637690 8.419503e-02 1.075 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 9.200168e-02 1.036 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 9.200168e-02 1.036 0 0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) R-HSA-5619111 9.200168e-02 1.036 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 9.200168e-02 1.036 0 0
TRAF3 deficiency - HSE R-HSA-5602571 9.200168e-02 1.036 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 1.207515e-01 0.918 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 1.207515e-01 0.918 0 0
Potassium transport channels R-HSA-1296067 1.207515e-01 0.918 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 1.207515e-01 0.918 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.207515e-01 0.918 0 0
Defective SLC12A1 causes Bartter syndrome 1 (BS1) R-HSA-5619104 1.207515e-01 0.918 0 0
Classical Kir channels R-HSA-1296053 1.485926e-01 0.828 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 8.487785e-02 1.071 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 8.487785e-02 1.071 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 9.461594e-02 1.024 0 0
Scavenging by Class F Receptors R-HSA-3000484 9.461594e-02 1.024 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.046552e-01 0.980 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.149668e-01 0.939 0 0
Erythropoietin activates RAS R-HSA-9027284 1.255236e-01 0.901 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 1.255236e-01 0.901 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.255236e-01 0.901 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.255236e-01 0.901 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.362998e-01 0.866 0 0
Phosphorylation of the APC/C R-HSA-176412 1.362998e-01 0.866 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.362998e-01 0.866 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.362998e-01 0.866 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 1.472710e-01 0.832 0 0
Signaling by EGFR in Cancer R-HSA-1643713 8.560004e-02 1.068 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.584141e-01 0.800 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 9.812803e-02 1.008 0 0
Formation of the Early Elongation Complex R-HSA-113418 9.812803e-02 1.008 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 1.697074e-01 0.770 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.848576e-02 1.007 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 1.034849e-01 0.985 0 0
Transcription of the HIV genome R-HSA-167172 1.010899e-01 0.995 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 1.532814e-01 0.815 0 0
mRNA Capping R-HSA-72086 1.046539e-01 0.980 0 0
Integrin signaling R-HSA-354192 1.323488e-01 0.878 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.274694e-01 0.895 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 1.301366e-01 0.886 0 0
Inwardly rectifying K+ channels R-HSA-1296065 1.251999e-01 0.902 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 1.357795e-01 0.867 0 0
GRB2 events in EGFR signaling R-HSA-179812 9.461594e-02 1.024 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 1.697074e-01 0.770 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.773722e-02 1.010 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.046552e-01 0.980 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 1.149668e-01 0.939 0 0
Regulation of RAS by GAPs R-HSA-5658442 1.191552e-01 0.924 0 0
G alpha (z) signalling events R-HSA-418597 1.473548e-01 0.832 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.021633e-01 0.991 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 8.678014e-02 1.062 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 1.207515e-01 0.918 0 0
MET interacts with TNS proteins R-HSA-8875513 1.485926e-01 0.828 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.255236e-01 0.901 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 1.584141e-01 0.800 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 1.181966e-01 0.927 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.360290e-02 1.029 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 1.622638e-01 0.790 0 0
Orc1 removal from chromatin R-HSA-68949 1.301366e-01 0.886 0 0
Switching of origins to a post-replicative state R-HSA-69052 1.228704e-01 0.911 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.021633e-01 0.991 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.186827e-01 0.926 0 0
G1/S Transition R-HSA-69206 8.597584e-02 1.066 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.626671e-01 0.789 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.154671e-01 0.938 0 0
ER-Phagosome pathway R-HSA-1236974 9.943580e-02 1.002 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.555946e-01 0.808 0 0
Breakdown of the nuclear lamina R-HSA-352238 9.200168e-02 1.036 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 1.251999e-01 0.902 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 1.546008e-01 0.811 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 1.546008e-01 0.811 0 0
Degradation of CDH1 R-HSA-9766229 1.138221e-01 0.944 0 0
Innate Immune System R-HSA-168249 1.320233e-01 0.879 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 1.383147e-01 0.859 0 0
Histamine receptors R-HSA-390650 1.485926e-01 0.828 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 1.472710e-01 0.832 0 0
Interleukin-17 signaling R-HSA-448424 1.095539e-01 0.960 0 0
Vesicle-mediated transport R-HSA-5653656 9.053323e-02 1.043 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.584189e-02 1.018 0 0
Ephrin signaling R-HSA-3928664 1.697074e-01 0.770 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 9.584189e-02 1.018 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 8.487785e-02 1.071 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.362998e-01 0.866 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 1.622638e-01 0.790 0 0
Gene expression (Transcription) R-HSA-74160 1.042978e-01 0.982 0 0
G0 and Early G1 R-HSA-1538133 1.251999e-01 0.902 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.425471e-01 0.846 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 9.897478e-02 1.004 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.425471e-01 0.846 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.425471e-01 0.846 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 1.207515e-01 0.918 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 8.487785e-02 1.071 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.046552e-01 0.980 0 0
Vpu mediated degradation of CD4 R-HSA-180534 1.396365e-01 0.855 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 1.470561e-01 0.833 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 1.470561e-01 0.833 0 0
Regulation of Apoptosis R-HSA-169911 1.546008e-01 0.811 0 0
EPHB-mediated forward signaling R-HSA-3928662 8.883859e-02 1.051 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 1.120595e-01 0.951 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 1.224429e-01 0.912 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 1.697074e-01 0.770 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.360290e-02 1.029 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.360290e-02 1.029 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.095539e-01 0.960 0 0
Signaling by NTRKs R-HSA-166520 9.146634e-02 1.039 0 0
Signaling by NOTCH3 R-HSA-9012852 1.473548e-01 0.832 0 0
Sensory processing of sound R-HSA-9659379 1.515999e-01 0.819 0 0
Signaling by FGFR2 R-HSA-5654738 1.566420e-01 0.805 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.010899e-01 0.995 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.370226e-01 0.863 0 0
OAS antiviral response R-HSA-8983711 9.461594e-02 1.024 0 0
Generic Transcription Pathway R-HSA-212436 1.536432e-01 0.813 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 1.183506e-01 0.927 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 1.362998e-01 0.866 0 0
Ion transport by P-type ATPases R-HSA-936837 8.519621e-02 1.070 0 0
Signaling by NOTCH4 R-HSA-9013694 1.274694e-01 0.895 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.459635e-02 1.024 0 0
Regulation of TP53 Degradation R-HSA-6804757 1.622638e-01 0.790 0 0
Response to metal ions R-HSA-5660526 1.472710e-01 0.832 0 0
SLC transporter disorders R-HSA-5619102 1.465458e-01 0.834 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 1.301366e-01 0.886 0 0
Degradation of DVL R-HSA-4641258 1.700384e-01 0.769 0 0
Degradation of AXIN R-HSA-4641257 1.700384e-01 0.769 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 1.700384e-01 0.769 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.700384e-01 0.769 0 0
S Phase R-HSA-69242 1.701756e-01 0.769 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 1.715800e-01 0.766 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 1.755539e-01 0.756 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 1.755539e-01 0.756 0 0
Signaling by MAP2K mutants R-HSA-9652169 1.755539e-01 0.756 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.755539e-01 0.756 0 0
Dopamine receptors R-HSA-390651 1.755539e-01 0.756 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 1.755539e-01 0.756 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.778420e-01 0.750 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 1.811301e-01 0.742 0 0
E2F mediated regulation of DNA replication R-HSA-113510 1.811301e-01 0.742 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 1.811301e-01 0.742 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 1.811301e-01 0.742 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.850695e-01 0.733 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 1.858951e-01 0.731 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 1.858951e-01 0.731 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 1.858951e-01 0.731 0 0
Stabilization of p53 R-HSA-69541 1.858951e-01 0.731 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.858951e-01 0.731 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 1.858951e-01 0.731 0 0
Synthesis of DNA R-HSA-69239 1.879458e-01 0.726 0 0
Asparagine N-linked glycosylation R-HSA-446203 1.882254e-01 0.725 0 0
Protein localization R-HSA-9609507 1.896114e-01 0.722 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 1.926628e-01 0.715 0 0
Creatine metabolism R-HSA-71288 1.926628e-01 0.715 0 0
Protein hydroxylation R-HSA-9629569 1.926628e-01 0.715 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 1.926628e-01 0.715 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.937455e-01 0.713 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.939641e-01 0.712 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 1.939641e-01 0.712 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 1.939641e-01 0.712 0 0
Cardiac conduction R-HSA-5576891 1.985135e-01 0.702 0 0
Pyruvate metabolism R-HSA-70268 1.992825e-01 0.701 0 0
IRS activation R-HSA-74713 2.016629e-01 0.695 0 0
G2 Phase R-HSA-68911 2.016629e-01 0.695 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.016629e-01 0.695 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 2.016629e-01 0.695 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 2.016629e-01 0.695 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.016629e-01 0.695 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 2.016629e-01 0.695 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 2.016629e-01 0.695 0 0
Suppression of autophagy R-HSA-9636569 2.016629e-01 0.695 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 2.016629e-01 0.695 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.016629e-01 0.695 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.016629e-01 0.695 0 0
PKMTs methylate histone lysines R-HSA-3214841 2.021181e-01 0.694 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.021181e-01 0.694 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 2.021181e-01 0.694 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 2.021181e-01 0.694 0 0
ERK/MAPK targets R-HSA-198753 2.042872e-01 0.690 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.042872e-01 0.690 0 0
Degradation of CRY and PER proteins R-HSA-9932298 2.103506e-01 0.677 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 2.103506e-01 0.677 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 2.103506e-01 0.677 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 2.103506e-01 0.677 0 0
Inositol phosphate metabolism R-HSA-1483249 2.125139e-01 0.673 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 2.159859e-01 0.666 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.159859e-01 0.666 0 0
Mitochondrial calcium ion transport R-HSA-8949215 2.159859e-01 0.666 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.194004e-01 0.659 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 2.219467e-01 0.654 0 0
Plus-strand DNA synthesis R-HSA-164525 2.269467e-01 0.644 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.269467e-01 0.644 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.269467e-01 0.644 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.269467e-01 0.644 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.269467e-01 0.644 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.269467e-01 0.644 0 0
Pentose phosphate pathway disease R-HSA-6791465 2.269467e-01 0.644 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.269467e-01 0.644 0 0
Phosphorylation of Emi1 R-HSA-176417 2.269467e-01 0.644 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 2.269467e-01 0.644 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 2.269467e-01 0.644 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 2.269467e-01 0.644 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.269467e-01 0.644 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 2.270263e-01 0.644 0 0
IRE1alpha activates chaperones R-HSA-381070 2.277320e-01 0.643 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 2.277427e-01 0.643 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 2.277427e-01 0.643 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.277427e-01 0.643 0 0
Proteasome assembly R-HSA-9907900 2.354571e-01 0.628 0 0
G1 Phase R-HSA-69236 2.354571e-01 0.628 0 0
Cyclin D associated events in G1 R-HSA-69231 2.354571e-01 0.628 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 2.372364e-01 0.625 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.395421e-01 0.621 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 2.395421e-01 0.621 0 0
PTEN Regulation R-HSA-6807070 2.397777e-01 0.620 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.397777e-01 0.620 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 2.439419e-01 0.613 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 2.439419e-01 0.613 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 2.439419e-01 0.613 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 2.439419e-01 0.613 0 0
Somitogenesis R-HSA-9824272 2.439419e-01 0.613 0 0
Extracellular matrix organization R-HSA-1474244 2.444888e-01 0.612 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 2.453431e-01 0.610 0 0
Mitochondrial protein degradation R-HSA-9837999 2.453431e-01 0.610 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.510364e-01 0.600 0 0
Hedgehog 'on' state R-HSA-5632684 2.510364e-01 0.600 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 2.513697e-01 0.600 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 2.513697e-01 0.600 0 0
Neurodegenerative Diseases R-HSA-8863678 2.513697e-01 0.600 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.513697e-01 0.600 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 2.513697e-01 0.600 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.514312e-01 0.600 0 0
Signaling by LTK in cancer R-HSA-9842640 2.514312e-01 0.600 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 2.514312e-01 0.600 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.514312e-01 0.600 0 0
Uncoating of the HIV Virion R-HSA-162585 2.514312e-01 0.600 0 0
G2/M DNA replication checkpoint R-HSA-69478 2.514312e-01 0.600 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 2.514312e-01 0.600 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 2.514312e-01 0.600 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 2.514312e-01 0.600 0 0
CREB phosphorylation R-HSA-199920 2.514312e-01 0.600 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 2.514312e-01 0.600 0 0
VLDL assembly R-HSA-8866423 2.514312e-01 0.600 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 2.592446e-01 0.586 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 2.592446e-01 0.586 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 2.592446e-01 0.586 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 2.632120e-01 0.580 0 0
G protein gated Potassium channels R-HSA-1296059 2.632120e-01 0.580 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 2.632120e-01 0.580 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 2.632120e-01 0.580 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 2.632120e-01 0.580 0 0
Laminin interactions R-HSA-3000157 2.632120e-01 0.580 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.632956e-01 0.580 0 0
RNA Polymerase II Transcription R-HSA-73857 2.648191e-01 0.577 0 0
Ca2+ pathway R-HSA-4086398 2.650002e-01 0.577 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.696617e-01 0.569 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 2.750561e-01 0.561 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.750561e-01 0.561 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 2.750561e-01 0.561 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 2.751417e-01 0.560 0 0
TRIF-mediated programmed cell death R-HSA-2562578 2.751417e-01 0.560 0 0
Recycling of eIF2:GDP R-HSA-72731 2.751417e-01 0.560 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 2.751417e-01 0.560 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 2.751417e-01 0.560 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 2.751417e-01 0.560 0 0
LDL remodeling R-HSA-8964041 2.751417e-01 0.560 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 2.751417e-01 0.560 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 2.754024e-01 0.560 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 2.754024e-01 0.560 0 0
Signaling by FGFR R-HSA-190236 2.754275e-01 0.560 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 2.791033e-01 0.554 0 0
Cristae formation R-HSA-8949613 2.868901e-01 0.542 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 2.868901e-01 0.542 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.868901e-01 0.542 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 2.868901e-01 0.542 0 0
Signaling by FGFR2 in disease R-HSA-5655253 2.869740e-01 0.542 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 2.884781e-01 0.540 0 0
Interleukin-1 signaling R-HSA-9020702 2.938319e-01 0.532 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 2.956637e-01 0.529 0 0
Reverse Transcription of HIV RNA R-HSA-162589 2.981026e-01 0.526 0 0
Minus-strand DNA synthesis R-HSA-164516 2.981026e-01 0.526 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 2.981026e-01 0.526 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 2.981026e-01 0.526 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 2.981026e-01 0.526 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 2.981026e-01 0.526 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 2.981026e-01 0.526 0 0
Activation of RAS in B cells R-HSA-1169092 2.981026e-01 0.526 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 2.981026e-01 0.526 0 0
Interleukin-23 signaling R-HSA-9020933 2.981026e-01 0.526 0 0
Telomere Extension By Telomerase R-HSA-171319 2.987028e-01 0.525 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 2.987028e-01 0.525 0 0
ABC transporter disorders R-HSA-5619084 3.004662e-01 0.522 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 3.035311e-01 0.518 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 3.043692e-01 0.517 0 0
Interleukin-1 family signaling R-HSA-446652 3.085848e-01 0.511 0 0
Signaling by Erythropoietin R-HSA-9006335 3.104838e-01 0.508 0 0
Late endosomal microautophagy R-HSA-9615710 3.104838e-01 0.508 0 0
Platelet calcium homeostasis R-HSA-418360 3.104838e-01 0.508 0 0
Regulation of PTEN stability and activity R-HSA-8948751 3.130854e-01 0.504 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 3.148129e-01 0.502 0 0
MAPK1 (ERK2) activation R-HSA-112411 3.203375e-01 0.494 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.203375e-01 0.494 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 3.203375e-01 0.494 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.203375e-01 0.494 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 3.203375e-01 0.494 0 0
Calcineurin activates NFAT R-HSA-2025928 3.203375e-01 0.494 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 3.203375e-01 0.494 0 0
GP1b-IX-V activation signalling R-HSA-430116 3.203375e-01 0.494 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 3.203375e-01 0.494 0 0
DAP12 signaling R-HSA-2424491 3.222231e-01 0.492 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 3.222231e-01 0.492 0 0
Interleukin-37 signaling R-HSA-9008059 3.222231e-01 0.492 0 0
EGFR downregulation R-HSA-182971 3.339117e-01 0.476 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 3.339117e-01 0.476 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.339117e-01 0.476 0 0
Molecules associated with elastic fibres R-HSA-2129379 3.339117e-01 0.476 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 3.368540e-01 0.473 0 0
Signaling by EGFR R-HSA-177929 3.392514e-01 0.469 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 3.392514e-01 0.469 0 0
Binding and entry of HIV virion R-HSA-173107 3.418694e-01 0.466 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.418694e-01 0.466 0 0
Regulation of CDH11 function R-HSA-9762292 3.418694e-01 0.466 0 0
PI3K/AKT activation R-HSA-198203 3.418694e-01 0.466 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 3.418694e-01 0.466 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 3.418694e-01 0.466 0 0
Signal attenuation R-HSA-74749 3.418694e-01 0.466 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.418694e-01 0.466 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 3.418694e-01 0.466 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 3.418694e-01 0.466 0 0
MAPK3 (ERK1) activation R-HSA-110056 3.418694e-01 0.466 0 0
Sperm Motility And Taxes R-HSA-1300642 3.418694e-01 0.466 0 0
Josephin domain DUBs R-HSA-5689877 3.418694e-01 0.466 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 3.418694e-01 0.466 0 0
Signaling by Leptin R-HSA-2586552 3.418694e-01 0.466 0 0
Circadian clock R-HSA-9909396 3.419642e-01 0.466 0 0
Regulation of TP53 Activity R-HSA-5633007 3.495171e-01 0.457 0 0
TCR signaling R-HSA-202403 3.563566e-01 0.448 0 0
Dual incision in TC-NER R-HSA-6782135 3.566655e-01 0.448 0 0
G-protein beta:gamma signalling R-HSA-397795 3.571029e-01 0.447 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 3.571029e-01 0.447 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.571029e-01 0.447 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 3.581116e-01 0.446 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 3.627204e-01 0.440 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.627204e-01 0.440 0 0
vRNP Assembly R-HSA-192905 3.627204e-01 0.440 0 0
vRNA Synthesis R-HSA-192814 3.627204e-01 0.440 0 0
Chylomicron assembly R-HSA-8963888 3.627204e-01 0.440 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 3.627204e-01 0.440 0 0
Bicarbonate transporters R-HSA-425381 3.627204e-01 0.440 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 3.627204e-01 0.440 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 3.627204e-01 0.440 0 0
PECAM1 interactions R-HSA-210990 3.627204e-01 0.440 0 0
Suppression of apoptosis R-HSA-9635465 3.627204e-01 0.440 0 0
Interleukin-2 signaling R-HSA-9020558 3.627204e-01 0.440 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 3.653381e-01 0.437 0 0
XBP1(S) activates chaperone genes R-HSA-381038 3.653381e-01 0.437 0 0
Extension of Telomeres R-HSA-180786 3.653510e-01 0.437 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.685902e-01 0.433 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.694362e-01 0.432 0 0
Metabolism of polyamines R-HSA-351202 3.740169e-01 0.427 0 0
Dual Incision in GG-NER R-HSA-5696400 3.799961e-01 0.420 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 3.799961e-01 0.420 0 0
Signal amplification R-HSA-392518 3.799961e-01 0.420 0 0
eNOS activation R-HSA-203615 3.799961e-01 0.420 0 0
NOD1/2 Signaling Pathway R-HSA-168638 3.799961e-01 0.420 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 3.799961e-01 0.420 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 3.826594e-01 0.417 0 0
Formation of paraxial mesoderm R-HSA-9793380 3.826594e-01 0.417 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 3.829120e-01 0.417 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 3.829120e-01 0.417 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 3.829120e-01 0.417 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 3.829120e-01 0.417 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 3.829120e-01 0.417 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 3.829120e-01 0.417 0 0
Plasmalogen biosynthesis R-HSA-75896 3.829120e-01 0.417 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 3.829120e-01 0.417 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 3.829120e-01 0.417 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 3.829120e-01 0.417 0 0
Activation of RAC1 R-HSA-428540 3.829120e-01 0.417 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 3.829120e-01 0.417 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 3.829120e-01 0.417 0 0
Integration of provirus R-HSA-162592 3.829120e-01 0.417 0 0
NCAM signaling for neurite out-growth R-HSA-375165 3.912748e-01 0.408 0 0
PERK regulates gene expression R-HSA-381042 3.913140e-01 0.407 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 3.929177e-01 0.406 0 0
Parasite infection R-HSA-9664407 3.929177e-01 0.406 0 0
Leishmania phagocytosis R-HSA-9664417 3.929177e-01 0.406 0 0
Downstream TCR signaling R-HSA-202424 3.941821e-01 0.404 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.024651e-01 0.395 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.024651e-01 0.395 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.024651e-01 0.395 0 0
MET activates RAS signaling R-HSA-8851805 4.024651e-01 0.395 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.024651e-01 0.395 0 0
Polymerase switching R-HSA-69091 4.024651e-01 0.395 0 0
Leading Strand Synthesis R-HSA-69109 4.024651e-01 0.395 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 4.024651e-01 0.395 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 4.024651e-01 0.395 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 4.024651e-01 0.395 0 0
p75NTR recruits signalling complexes R-HSA-209543 4.024651e-01 0.395 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.024651e-01 0.395 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 4.025383e-01 0.395 0 0
RNA Polymerase III Transcription R-HSA-74158 4.025383e-01 0.395 0 0
RUNX2 regulates bone development R-HSA-8941326 4.025383e-01 0.395 0 0
FLT3 signaling in disease R-HSA-9682385 4.025383e-01 0.395 0 0
Glycosphingolipid transport R-HSA-9845576 4.025383e-01 0.395 0 0
Triglyceride catabolism R-HSA-163560 4.025383e-01 0.395 0 0
G1/S-Specific Transcription R-HSA-69205 4.025383e-01 0.395 0 0
FGFR2 mutant receptor activation R-HSA-1839126 4.025383e-01 0.395 0 0
RET signaling R-HSA-8853659 4.025383e-01 0.395 0 0
tRNA processing R-HSA-72306 4.065765e-01 0.391 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 4.084107e-01 0.389 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 4.117705e-01 0.385 0 0
Mitochondrial biogenesis R-HSA-1592230 4.130626e-01 0.384 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 4.136634e-01 0.383 0 0
Clathrin-mediated endocytosis R-HSA-8856828 4.155775e-01 0.381 0 0
Cellular response to hypoxia R-HSA-1234174 4.169247e-01 0.380 0 0
Formation of axial mesoderm R-HSA-9796292 4.213998e-01 0.375 0 0
Frs2-mediated activation R-HSA-170968 4.213998e-01 0.375 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 4.213998e-01 0.375 0 0
CD28 dependent Vav1 pathway R-HSA-389359 4.213998e-01 0.375 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 4.213998e-01 0.375 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 4.213998e-01 0.375 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 4.246844e-01 0.372 0 0
MET promotes cell motility R-HSA-8875878 4.246844e-01 0.372 0 0
Elastic fibre formation R-HSA-1566948 4.246844e-01 0.372 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 4.370169e-01 0.360 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 4.380738e-01 0.358 0 0
Removal of the Flap Intermediate R-HSA-69166 4.397356e-01 0.357 0 0
Retrograde neurotrophin signalling R-HSA-177504 4.397356e-01 0.357 0 0
CRMPs in Sema3A signaling R-HSA-399956 4.397356e-01 0.357 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 4.397356e-01 0.357 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 4.397356e-01 0.357 0 0
Malate-aspartate shuttle R-HSA-9856872 4.397356e-01 0.357 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 4.397356e-01 0.357 0 0
Regulation of KIT signaling R-HSA-1433559 4.397356e-01 0.357 0 0
Signaling by FGFR4 in disease R-HSA-5655291 4.397356e-01 0.357 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 4.397356e-01 0.357 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 4.463963e-01 0.350 0 0
Diseases of Immune System R-HSA-5260271 4.463963e-01 0.350 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 4.463963e-01 0.350 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 4.504916e-01 0.346 0 0
Potential therapeutics for SARS R-HSA-9679191 4.549611e-01 0.342 0 0
MITF-M-dependent gene expression R-HSA-9856651 4.549611e-01 0.342 0 0
Formation of the cornified envelope R-HSA-6809371 4.566740e-01 0.340 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 4.570792e-01 0.340 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 4.574914e-01 0.340 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 4.574914e-01 0.340 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 4.574914e-01 0.340 0 0
G beta:gamma signalling through BTK R-HSA-8964315 4.574914e-01 0.340 0 0
Processive synthesis on the lagging strand R-HSA-69183 4.574914e-01 0.340 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 4.574914e-01 0.340 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 4.574914e-01 0.340 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 4.574914e-01 0.340 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 4.574914e-01 0.340 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 4.574914e-01 0.340 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 4.574914e-01 0.340 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 4.574914e-01 0.340 0 0
Other semaphorin interactions R-HSA-416700 4.574914e-01 0.340 0 0
DCC mediated attractive signaling R-HSA-418885 4.574914e-01 0.340 0 0
p75NTR signals via NF-kB R-HSA-193639 4.574914e-01 0.340 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.581212e-01 0.339 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 4.588348e-01 0.338 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 4.676420e-01 0.330 0 0
HIV Transcription Initiation R-HSA-167161 4.676420e-01 0.330 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 4.676420e-01 0.330 0 0
FOXO-mediated transcription R-HSA-9614085 4.720414e-01 0.326 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 4.746855e-01 0.324 0 0
Phase 4 - resting membrane potential R-HSA-5576886 4.746855e-01 0.324 0 0
Prolonged ERK activation events R-HSA-169893 4.746855e-01 0.324 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 4.746855e-01 0.324 0 0
Activation of SMO R-HSA-5635838 4.746855e-01 0.324 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 4.746855e-01 0.324 0 0
Attachment and Entry R-HSA-9678110 4.746855e-01 0.324 0 0
Negative regulation of FLT3 R-HSA-9706369 4.746855e-01 0.324 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 4.780816e-01 0.320 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 4.780816e-01 0.320 0 0
Activation of GABAB receptors R-HSA-991365 4.780816e-01 0.320 0 0
GABA B receptor activation R-HSA-977444 4.780816e-01 0.320 0 0
ABC-family proteins mediated transport R-HSA-382556 4.789517e-01 0.320 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 4.883952e-01 0.311 0 0
TBC/RABGAPs R-HSA-8854214 4.883952e-01 0.311 0 0
Signaling by SCF-KIT R-HSA-1433557 4.883952e-01 0.311 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 4.913358e-01 0.309 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 4.913358e-01 0.309 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 4.913358e-01 0.309 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 4.913358e-01 0.309 0 0
Fibronectin matrix formation R-HSA-1566977 4.913358e-01 0.309 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 4.913358e-01 0.309 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 4.913358e-01 0.309 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 4.913358e-01 0.309 0 0
Galactose catabolism R-HSA-70370 4.913358e-01 0.309 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 4.913358e-01 0.309 0 0
Signaling by FGFR in disease R-HSA-1226099 4.914154e-01 0.309 0 0
DAP12 interactions R-HSA-2172127 4.985803e-01 0.302 0 0
Netrin-1 signaling R-HSA-373752 4.985803e-01 0.302 0 0
Amine ligand-binding receptors R-HSA-375280 4.985803e-01 0.302 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 4.993396e-01 0.302 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 5.074593e-01 0.295 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 5.074593e-01 0.295 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 5.074593e-01 0.295 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 5.074593e-01 0.295 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 5.074593e-01 0.295 0 0
Uptake and function of anthrax toxins R-HSA-5210891 5.074593e-01 0.295 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 5.074593e-01 0.295 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 5.086347e-01 0.294 0 0
Signaling by TGFB family members R-HSA-9006936 5.100264e-01 0.292 0 0
RSV-host interactions R-HSA-9833110 5.129458e-01 0.290 0 0
Toll-like Receptor Cascades R-HSA-168898 5.139863e-01 0.289 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 5.185565e-01 0.285 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 5.185565e-01 0.285 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 5.230726e-01 0.281 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 5.230726e-01 0.281 0 0
GAB1 signalosome R-HSA-180292 5.230726e-01 0.281 0 0
Presynaptic function of Kainate receptors R-HSA-500657 5.230726e-01 0.281 0 0
Platelet sensitization by LDL R-HSA-432142 5.230726e-01 0.281 0 0
Tie2 Signaling R-HSA-210993 5.230726e-01 0.281 0 0
Mismatch Repair R-HSA-5358508 5.230726e-01 0.281 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 5.230726e-01 0.281 0 0
Platelet homeostasis R-HSA-418346 5.262578e-01 0.279 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 5.283440e-01 0.277 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 5.283440e-01 0.277 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 5.378316e-01 0.269 0 0
GPER1 signaling R-HSA-9634597 5.379957e-01 0.269 0 0
Co-stimulation by CD28 R-HSA-389356 5.379957e-01 0.269 0 0
NGF-stimulated transcription R-HSA-9031628 5.379957e-01 0.269 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 5.381919e-01 0.269 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 5.381919e-01 0.269 0 0
Regulation of signaling by CBL R-HSA-912631 5.381919e-01 0.269 0 0
Translesion Synthesis by POLH R-HSA-110320 5.381919e-01 0.269 0 0
The NLRP3 inflammasome R-HSA-844456 5.381919e-01 0.269 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 5.381919e-01 0.269 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 5.381919e-01 0.269 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 5.381919e-01 0.269 0 0
STING mediated induction of host immune responses R-HSA-1834941 5.381919e-01 0.269 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 5.381919e-01 0.269 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 5.381919e-01 0.269 0 0
Signaling by MET R-HSA-6806834 5.383882e-01 0.269 0 0
DNA Damage Bypass R-HSA-73893 5.475103e-01 0.262 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 5.528329e-01 0.257 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 5.528329e-01 0.257 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 5.528329e-01 0.257 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 5.528329e-01 0.257 0 0
Glycogen synthesis R-HSA-3322077 5.528329e-01 0.257 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 5.609248e-01 0.251 0 0
The phototransduction cascade R-HSA-2514856 5.661248e-01 0.247 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 5.670105e-01 0.246 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 5.670105e-01 0.246 0 0
G-protein activation R-HSA-202040 5.670105e-01 0.246 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 5.670105e-01 0.246 0 0
Early Phase of HIV Life Cycle R-HSA-162594 5.670105e-01 0.246 0 0
Lagging Strand Synthesis R-HSA-69186 5.670105e-01 0.246 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 5.670105e-01 0.246 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 5.670105e-01 0.246 0 0
Phenylalanine metabolism R-HSA-8964208 5.670105e-01 0.246 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 5.670105e-01 0.246 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 5.670105e-01 0.246 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 5.670105e-01 0.246 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 5.722769e-01 0.242 0 0
mRNA 3'-end processing R-HSA-72187 5.752231e-01 0.240 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 5.752231e-01 0.240 0 0
Cellular response to chemical stress R-HSA-9711123 5.800901e-01 0.237 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 5.807395e-01 0.236 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 5.807395e-01 0.236 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 5.807395e-01 0.236 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 5.807395e-01 0.236 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 5.807395e-01 0.236 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 5.807395e-01 0.236 0 0
Androgen biosynthesis R-HSA-193048 5.807395e-01 0.236 0 0
Attachment and Entry R-HSA-9694614 5.807395e-01 0.236 0 0
Assembly Of The HIV Virion R-HSA-175474 5.807395e-01 0.236 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 5.807395e-01 0.236 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 5.827836e-01 0.234 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 5.899148e-01 0.229 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 5.940339e-01 0.226 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 5.940339e-01 0.226 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 5.940339e-01 0.226 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 5.940339e-01 0.226 0 0
LDL clearance R-HSA-8964038 5.940339e-01 0.226 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 5.940339e-01 0.226 0 0
Signaling by KIT in disease R-HSA-9669938 5.940339e-01 0.226 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 6.000798e-01 0.222 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.069076e-01 0.217 0 0
Biosynthesis of maresins R-HSA-9018682 6.069076e-01 0.217 0 0
Formation of the ureteric bud R-HSA-9830674 6.069076e-01 0.217 0 0
Growth hormone receptor signaling R-HSA-982772 6.069076e-01 0.217 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 6.102156e-01 0.215 0 0
TNF signaling R-HSA-75893 6.102156e-01 0.215 0 0
IRS-mediated signalling R-HSA-112399 6.186132e-01 0.209 0 0
CYP2E1 reactions R-HSA-211999 6.193739e-01 0.208 0 0
Thromboxane signalling through TP receptor R-HSA-428930 6.193739e-01 0.208 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 6.193739e-01 0.208 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 6.193739e-01 0.208 0 0
Plasma lipoprotein assembly R-HSA-8963898 6.193739e-01 0.208 0 0
Complex III assembly R-HSA-9865881 6.193739e-01 0.208 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 6.193739e-01 0.208 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 6.268710e-01 0.203 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 6.314455e-01 0.200 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 6.314455e-01 0.200 0 0
Fertilization R-HSA-1187000 6.314455e-01 0.200 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 6.314455e-01 0.200 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 6.314716e-01 0.200 0 0
Leishmania infection R-HSA-9658195 6.322266e-01 0.199 0 0
Parasitic Infection Pathways R-HSA-9824443 6.322266e-01 0.199 0 0
Triglyceride metabolism R-HSA-8979227 6.349894e-01 0.197 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 6.349894e-01 0.197 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 6.387852e-01 0.195 0 0
GABA receptor activation R-HSA-977443 6.429690e-01 0.192 0 0
tRNA Aminoacylation R-HSA-379724 6.429690e-01 0.192 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 6.431349e-01 0.192 0 0
MET activates PTK2 signaling R-HSA-8874081 6.431349e-01 0.192 0 0
Suppression of phagosomal maturation R-HSA-9637687 6.431349e-01 0.192 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 6.431349e-01 0.192 0 0
Collagen formation R-HSA-1474290 6.504818e-01 0.187 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 6.508104e-01 0.187 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 6.508104e-01 0.187 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 6.544544e-01 0.184 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 6.544544e-01 0.184 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 6.544544e-01 0.184 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 6.544544e-01 0.184 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 6.544544e-01 0.184 0 0
Insulin processing R-HSA-264876 6.544544e-01 0.184 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 6.544544e-01 0.184 0 0
Signaling by FGFR3 in disease R-HSA-5655332 6.544544e-01 0.184 0 0
Signaling by PDGF R-HSA-186797 6.585143e-01 0.181 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 6.654154e-01 0.177 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 6.654154e-01 0.177 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 6.654154e-01 0.177 0 0
Inflammasomes R-HSA-622312 6.654154e-01 0.177 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 6.654154e-01 0.177 0 0
Pyroptosis R-HSA-5620971 6.654154e-01 0.177 0 0
Potassium Channels R-HSA-1296071 6.691967e-01 0.174 0 0
Interferon gamma signaling R-HSA-877300 6.732409e-01 0.172 0 0
Insulin receptor signalling cascade R-HSA-74751 6.735130e-01 0.172 0 0
IGF1R signaling cascade R-HSA-2428924 6.735130e-01 0.172 0 0
Thyroxine biosynthesis R-HSA-209968 6.760294e-01 0.170 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 6.760294e-01 0.170 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 6.760294e-01 0.170 0 0
Termination of translesion DNA synthesis R-HSA-5656169 6.760294e-01 0.170 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 6.760294e-01 0.170 0 0
Glucagon-type ligand receptors R-HSA-420092 6.760294e-01 0.170 0 0
DARPP-32 events R-HSA-180024 6.760294e-01 0.170 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 6.808097e-01 0.167 0 0
Regulation of insulin secretion R-HSA-422356 6.812606e-01 0.167 0 0
Activation of the pre-replicative complex R-HSA-68962 6.863073e-01 0.163 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 6.863073e-01 0.163 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 6.863073e-01 0.163 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 6.863073e-01 0.163 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 6.863073e-01 0.163 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 6.863073e-01 0.163 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 6.863073e-01 0.163 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 6.962598e-01 0.157 0 0
Budding and maturation of HIV virion R-HSA-162588 6.962598e-01 0.157 0 0
Downstream signal transduction R-HSA-186763 6.962598e-01 0.157 0 0
Regulated Necrosis R-HSA-5218859 7.019025e-01 0.154 0 0
DNA strand elongation R-HSA-69190 7.058971e-01 0.151 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 7.058971e-01 0.151 0 0
Nuclear RNA decay R-HSA-9930044 7.152292e-01 0.146 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 7.152292e-01 0.146 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.152292e-01 0.146 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.152292e-01 0.146 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 7.152292e-01 0.146 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.154808e-01 0.145 0 0
ECM proteoglycans R-HSA-3000178 7.218247e-01 0.142 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 7.242657e-01 0.140 0 0
Effects of PIP2 hydrolysis R-HSA-114508 7.242657e-01 0.140 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 7.242657e-01 0.140 0 0
Integration of energy metabolism R-HSA-163685 7.251369e-01 0.140 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 7.282115e-01 0.138 0 0
Mitophagy R-HSA-5205647 7.330160e-01 0.135 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 7.330160e-01 0.135 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 7.330160e-01 0.135 0 0
Phosphate bond hydrolysis by NUDT proteins R-HSA-2393930 7.330160e-01 0.135 0 0
ROS and RNS production in phagocytes R-HSA-1222556 7.406128e-01 0.130 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 7.414891e-01 0.130 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 7.414891e-01 0.130 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 7.414891e-01 0.130 0 0
Oncogene Induced Senescence R-HSA-2559585 7.414891e-01 0.130 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 7.466302e-01 0.127 0 0
GPVI-mediated activation cascade R-HSA-114604 7.496939e-01 0.125 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 7.554894e-01 0.122 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 7.576387e-01 0.121 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 7.576387e-01 0.121 0 0
Phenylalanine and tyrosine metabolism R-HSA-8963691 7.576387e-01 0.121 0 0
FCERI mediated MAPK activation R-HSA-2871796 7.613862e-01 0.118 0 0
Integrin cell surface interactions R-HSA-216083 7.639681e-01 0.117 0 0
G alpha (12/13) signalling events R-HSA-416482 7.639681e-01 0.117 0 0
FCERI mediated NF-kB activation R-HSA-2871837 7.648168e-01 0.116 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 7.653318e-01 0.116 0 0
RAS processing R-HSA-9648002 7.727812e-01 0.112 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 7.727812e-01 0.112 0 0
Plasma lipoprotein clearance R-HSA-8964043 7.727812e-01 0.112 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 7.727812e-01 0.112 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 7.799945e-01 0.108 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 7.799945e-01 0.108 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 7.799945e-01 0.108 0 0
Generation of second messenger molecules R-HSA-202433 7.799945e-01 0.108 0 0
Glycogen metabolism R-HSA-8982491 7.799945e-01 0.108 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 7.799945e-01 0.108 0 0
Interleukin-2 family signaling R-HSA-451927 7.799945e-01 0.108 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 7.802677e-01 0.108 0 0
Gastrulation R-HSA-9758941 7.848569e-01 0.105 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 7.869793e-01 0.104 0 0
Neddylation R-HSA-8951664 7.871020e-01 0.104 0 0
Rab regulation of trafficking R-HSA-9007101 7.927926e-01 0.101 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 7.937427e-01 0.100 0 0
Signaling by FGFR1 in disease R-HSA-5655302 7.937427e-01 0.100 0 0
Ion channel transport R-HSA-983712 7.987139e-01 0.098 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.002918e-01 0.097 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 8.002918e-01 0.097 0 0
Death Receptor Signaling R-HSA-73887 8.035157e-01 0.095 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 8.066334e-01 0.093 0 0
Signaling by FGFR4 R-HSA-5654743 8.066334e-01 0.093 0 0
G alpha (q) signalling events R-HSA-416476 8.077247e-01 0.093 0 0
Methylation R-HSA-156581 8.127739e-01 0.090 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 8.127739e-01 0.090 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 8.187198e-01 0.087 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.187198e-01 0.087 0 0
Signaling by FGFR3 R-HSA-5654741 8.187198e-01 0.087 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 8.209517e-01 0.086 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.244773e-01 0.084 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.244773e-01 0.084 0 0
Regulation of pyruvate metabolism R-HSA-9861718 8.244773e-01 0.084 0 0
Signaling by TGFBR3 R-HSA-9839373 8.244773e-01 0.084 0 0
Regulation of TNFR1 signaling R-HSA-5357905 8.244773e-01 0.084 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 8.276693e-01 0.082 0 0
Cell surface interactions at the vascular wall R-HSA-202733 8.341969e-01 0.079 0 0
Plasma lipoprotein remodeling R-HSA-8963899 8.354504e-01 0.078 0 0
Signaling by Insulin receptor R-HSA-74752 8.399827e-01 0.076 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 8.399827e-01 0.076 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 8.406774e-01 0.075 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.439069e-01 0.074 0 0
PI3K Cascade R-HSA-109704 8.457387e-01 0.073 0 0
Adipogenesis R-HSA-9843745 8.517913e-01 0.070 0 0
Keratinization R-HSA-6805567 8.521093e-01 0.070 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 8.587447e-01 0.066 0 0
Amino acids regulate mTORC1 R-HSA-9639288 8.599799e-01 0.066 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 8.653939e-01 0.063 0 0
Leishmania parasite growth and survival R-HSA-9664433 8.653939e-01 0.063 0 0
Post-translational protein phosphorylation R-HSA-8957275 8.656703e-01 0.063 0 0
Paracetamol ADME R-HSA-9753281 8.687372e-01 0.061 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 8.690152e-01 0.061 0 0
Metabolism of amine-derived hormones R-HSA-209776 8.729086e-01 0.059 0 0
NRAGE signals death through JNK R-HSA-193648 8.729086e-01 0.059 0 0
Signaling by FGFR1 R-HSA-5654736 8.729086e-01 0.059 0 0
Dectin-2 family R-HSA-5621480 8.769477e-01 0.057 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 8.808587e-01 0.055 0 0
Peroxisomal protein import R-HSA-9033241 8.846457e-01 0.053 0 0
Aquaporin-mediated transport R-HSA-445717 8.918629e-01 0.050 0 0
Heme signaling R-HSA-9707616 8.953007e-01 0.048 0 0
Complex I biogenesis R-HSA-6799198 8.986294e-01 0.046 0 0
Xenobiotics R-HSA-211981 9.018525e-01 0.045 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 9.109208e-01 0.041 0 0
Kidney development R-HSA-9830369 9.109208e-01 0.041 0 0
Metabolism of steroid hormones R-HSA-196071 9.109208e-01 0.041 0 0
Bacterial Infection Pathways R-HSA-9824439 9.127361e-01 0.040 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.137538e-01 0.039 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.153132e-01 0.038 0 0
COPII-mediated vesicle transport R-HSA-204005 9.191528e-01 0.037 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.191528e-01 0.037 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.196172e-01 0.036 0 0
Metabolism of cofactors R-HSA-8978934 9.217244e-01 0.035 0 0
Purine catabolism R-HSA-74259 9.242144e-01 0.034 0 0
Aspirin ADME R-HSA-9749641 9.266253e-01 0.033 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 9.266253e-01 0.033 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.266253e-01 0.033 0 0
G alpha (i) signalling events R-HSA-418594 9.330996e-01 0.030 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.355274e-01 0.029 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.395656e-01 0.027 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.395656e-01 0.027 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.395656e-01 0.027 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.433513e-01 0.025 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.533463e-01 0.021 0 0
Neurotransmitter release cycle R-HSA-112310 9.590111e-01 0.018 0 0
FCGR activation R-HSA-2029481 9.639892e-01 0.016 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.683638e-01 0.014 0 0
Visual phototransduction R-HSA-2187338 9.693352e-01 0.014 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.717535e-01 0.012 0 0
GPCR downstream signalling R-HSA-388396 9.731791e-01 0.012 0 0
PPARA activates gene expression R-HSA-1989781 9.753810e-01 0.011 0 0
Signaling by GPCR R-HSA-372790 9.758721e-01 0.011 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.767023e-01 0.010 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.839805e-01 0.007 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.844916e-01 0.007 0 0
G alpha (s) signalling events R-HSA-418555 9.846443e-01 0.007 0 0
Peptide hormone metabolism R-HSA-2980736 9.854655e-01 0.006 0 0
Respiratory electron transport R-HSA-611105 9.873814e-01 0.006 0 0
Metabolism of nucleotides R-HSA-15869 9.890003e-01 0.005 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.894923e-01 0.005 0 0
Nucleotide catabolism R-HSA-8956319 9.904672e-01 0.004 0 0
Transport of small molecules R-HSA-382551 9.930522e-01 0.003 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.945115e-01 0.002 0 0
Arachidonate metabolism R-HSA-2142753 9.959035e-01 0.002 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.971493e-01 0.001 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.974851e-01 0.001 0 0
Diseases of glycosylation R-HSA-3781865 9.986004e-01 0.001 0 0
Peptide ligand-binding receptors R-HSA-375276 9.986887e-01 0.001 0 0
Metabolism of steroids R-HSA-8957322 9.989442e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.993240e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.993388e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.995531e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.997750e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.998550e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999436e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999820e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999868e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999963e-01 0.000 0 0
Biological oxidations R-HSA-211859 9.999966e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways