FLT1
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
Y Sites Probabilities
Log-Odds: Y Sites / Y Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A5A3E0 | Y1062 | Sugiyama | POTEF A26C1B | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______ |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| O00116 | Y645 | Sugiyama | AGPS AAG5 | QWLKESIsDVGFGMLKSVKEyVDPNNIFGNRNLL_______ |
| O00193 | Y84 | Sugiyama | SMAP C11orf58 | TSHFRTGEEDKKINEELEsQyQQsMDsKLSGRYRRHCGLGF |
| O00299 | Y233 | Sugiyama | CLIC1 G6 NCC27 | AyAREEFAstCPDDEEIELAyEQVAKALK____________ |
| O00469 | Y444 | Sugiyama | PLOD2 | LWSNFWGALSPDGYYARsEDyVDIVQGNRVGVWNVPYMANV |
| O00469 | Y586 | Sugiyama | PLOD2 | FWFPIFSEKACDELVEEMEHyGKWSGGKHHDsRIsGGyENV |
| O00488 | Y97 | Sugiyama | ZNF593 ZT86 | KTHFRSKDHKKRLKQLsVEPysQEEAERAAGMGSYVPPRRL |
| O14602 | Y35 | Sugiyama | EIF1AY | GKNENESEKRELVFKEDGQEyAQVIKMLGNGRLEALCFDGV |
| O14639 | Y383 | Sugiyama | ABLIM1 ABLIM KIAA0059 LIMAB1 | sIPGsPGHtIyAKVDNEILDyKDLAAIPKVKAIYDIERPDL |
| O14818 | T147 | Sugiyama | PSMA7 HSPC | FGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKS |
| O14818 | Y145 | Sugiyama | PSMA7 HSPC | RPFGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGA |
| O14818 | Y153 | Sugiyama | PSMA7 HSPC | IVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFLE |
| O14818 | Y176 | Sugiyama | PSMA7 HSPC | WKANAIGRGAKSVREFLEKNyTDEAIETDDLTIKLVIKALL |
| O14950 | Y143 | Sugiyama | MYL12B MRLC2 MYLC2B | LRELLttMGDRFtDEEVDELyREAPIDKKGNFNyIEFtRIL |
| O14950 | Y156 | Sugiyama | MYL12B MRLC2 MYLC2B | DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____ |
| O14974 | Y911 | Sugiyama | PPP1R12A MBS MYPT1 | ETssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDSTD |
| O14979 | T165 | Sugiyama | HNRNPDL HNRPDL JKTBP | QDDGKMFIGGLSWDTsKKDLtEyLSRFGEVVDCtIKTDPVT |
| O14979 | Y167 | Sugiyama | HNRNPDL HNRPDL JKTBP | DGKMFIGGLSWDTsKKDLtEyLSRFGEVVDCtIKTDPVTGR |
| O15067 | Y538 | Sugiyama | PFAS KIAA0361 | GAGGNGNVLKELsDPAGAIIytsRFQLGDPTLNALEIWGAE |
| O15234 | Y240 | Sugiyama | CASC3 MLN51 | HDKFREDEQAPKSRQELIALyGyDIRSAHNPDDIKPRRIRK |
| O15234 | Y242 | Sugiyama | CASC3 MLN51 | KFREDEQAPKSRQELIALyGyDIRSAHNPDDIKPRRIRKPR |
| O15371 | Y202 | Sugiyama | EIF3D EIF3S7 | MRyLEVSEPQDIECCGALEyyDKAFDRITTRSEKPLRSIKR |
| O15371 | Y50 | Sugiyama | EIF3D EIF3S7 | yQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQYA |
| O15372 | Y350 | Sugiyama | EIF3H EIF3S3 | IKEFTAQNLGKLFMAQALQEyNN__________________ |
| O43390 | Y136 | Sugiyama | HNRNPR HNRPR | QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY |
| O43390 | Y376 | Sugiyama | HNRNPR HNRPR | ILEKSFSEFGKLERVKKLKDyAFVHFEDRGAAVKAMDEMNG |
| O43390 | Y434 | Sugiyama | HNRNPR HNRPR | KKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGG |
| O43390 | Y436 | Sugiyama | HNRNPR HNRPR | RKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGGRG |
| O43448 | Y311 | Sugiyama | KCNAB3 KCNA3B | LITSKYDGRVPDTCRASIKGyQWLKDKVQSEDGKKQQAKVM |
| O43707 | Y234 | Sugiyama | ACTN4 | KLRKDDPVTNLNNAFEVAEKyLDIPKMLDAEDIVNtARPDE |
| O43707 | Y397 | Sugiyama | ACTN4 | GKMVSDINNGWQHLEQAEKGyEEWLLNEIRRLERLDHLAEK |
| O43707 | Y441 | Sugiyama | ACTN4 | KAsIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEs |
| O43707 | Y878 | Sugiyama | ACTN4 | DKNFITAEELRRELPPDQAEyCIARMAPyQGPDAVPGALDy |
| O43719 | Y650 | Sugiyama | HTATSF1 | EEDtyEKVFDDEsDEKEDEEyADEKGLEAADKKAEEGDADE |
| O43765 | Y195 | Sugiyama | SGTA SGT SGT1 | HVEAVAYYKKALELDPDNEtyKsNLKIAELKLREAPSPTGG |
| O43823 | Y311 | Sugiyama | AKAP8 AKAP95 | RGFDRFGPDGTGRKRKQFQLyEEPDtKLARVDsEGDFsEND |
| O43852 | Y106 | Sugiyama | CALU | GFVtVDELKDWIKFAQKRWIyEDVERQWKGHDLNEDGLVsW |
| O43852 | Y129 | Sugiyama | CALU | VERQWKGHDLNEDGLVsWEEyKNATYGYVLDDPDPDDGFNY |
| O43852 | Y185 | Sugiyama | CALU | KDGDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNAD |
| O43852 | Y187 | Sugiyama | CALU | GDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNADGF |
| O43852 | Y263 | Sugiyama | CALU | KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG |
| O43852 | Y47 | Sugiyama | CALU | RVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQLtPE |
| O60361 | Y136 | Sugiyama | NME2P1 | SLRFKPEELVDYKSCAHDWVyE___________________ |
| O60488 | Y582 | Sugiyama | ACSL4 ACS4 FACL4 LACS4 | DGCLQIIDRKKDLVKLQAGEyVsLGKVEAALKNCPLIDNIC |
| O60506 | Y133 | Sugiyama | SYNCRIP HNRPQ NSAP1 | ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY |
| O60506 | Y373 | Sugiyama | SYNCRIP HNRPQ NSAP1 | ILEKAFsQFGKLERVKKLKDyAFIHFDERDGAVKAMEEMNG |
| O60664 | Y95 | Sugiyama | PLIN3 M6PRBP1 TIP47 | VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE |
| O60716 | Y228 | Sugiyama | CTNND1 KIAA0384 | yPPDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGy |
| O60739 | Y30 | Sugiyama | EIF1B | FDPFADATKGDDLLPAGTEDyIHIRIQQRNGRKtLttVQGI |
| O60814 | Y41 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| O60814 | Y43 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| O60841 | S186 | Sugiyama | EIF5B IF2 KIAA0741 | EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN |
| O60841 | Y134 | Sugiyama | EIF5B IF2 KIAA0741 | EELEDKDsKSKKTAKPKVEMysGsDDDDDFNKLPKKAKGKA |
| O60934 | Y679 | Sugiyama | NBN NBS NBS1 P95 | FRSLVIKNSTSRNPSGINDDyGQLKNFKKFKKVTYPGAGKL |
| O75116 | Y936 | Sugiyama | ROCK2 KIAA0619 | EITLTKADSEQLARsIAEEQysDLEKEKIMKELEIKEMMAR |
| O75347 | Y75 | Sugiyama | TBCA | EILQEsRMMIPDCQRRLEAAyLDLQRILENEKDLEEAEEyK |
| O75347 | Y94 | Sugiyama | TBCA | AyLDLQRILENEKDLEEAEEyKEARLVLDsVKLEA______ |
| O75348 | Y47 | Sugiyama | ATP6V1G1 ATP6G ATP6G1 ATP6J | KRKNRRLKQAKEEAQAEIEQyRLQREKEFKAKEAAALGsRG |
| O75683 | Y10 | Sugiyama | SURF6 SURF-6 | ___________MASLLAKDAyLQsLAKKICSHsAPEQQART |
| O75874 | Y391 | Sugiyama | IDH1 PICD | FMTKDLAACIKGLPNVQRsDyLNTFEFMDKLGENLKIKLAQ |
| O94906 | Y105 | Sugiyama | PRPF6 C20orf14 | AGSLFSSGPYEKDDEEADAIyAALDKRMDERRKERREQREK |
| O95218 | Y167 | Sugiyama | ZRANB2 ZIS ZNF265 | EVEDKEsEGEEEDEDEDLsKyKLDEDEDEDDADLsKyNLDA |
| O95347 | Y938 | Sugiyama | SMC2 CAPE SMC2L1 PRO0324 | SKHKREAEDGAAKVSKMLKDyDWINAERHLFGQPNSAYDFK |
| O95573 | Y591 | Sugiyama | ACSL3 ACS3 FACL3 LACS3 | DGCLKIIDRKKDLVKLQAGEyVsLGKVEAALKNLPLVDNIC |
| O95757 | Y627 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | MIMQDKLEKERNDAKNAVEEyVyDFRDRLGtVYEKFITPED |
| O95757 | Y629 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | MQDKLEKERNDAKNAVEEyVyDFRDRLGtVYEKFITPEDLS |
| O95817 | Y240 | Sugiyama | BAG3 BIS | AAQPsFHQAQKTHyPAQQGEyQtHQPVyHKIQGDDWEPRPL |
| O95817 | Y247 | Sugiyama | BAG3 BIS | QAQKTHyPAQQGEyQtHQPVyHKIQGDDWEPRPLRAAsPFR |
| O95881 | Y137 | Sugiyama | TXNDC12 TLP19 UNQ713/PRO1376 | FLDPSGKVHPEIINENGNPsyKyFyVsAEQVVQGMKEAQER |
| O95926 | Y210 | Sugiyama | SYF2 CBPIN GCIPIP | IEKRDKYSRRRPYNDDADIDyINERNAKFNKKAERFYGKYT |
| O96019 | T67 | Sugiyama | ACTL6A BAF53 BAF53A INO80K | RDDGsTLMEIDGDKGKQGGPtyyIDtNALRVPRENMEAIsP |
| O96019 | Y69 | Sugiyama | ACTL6A BAF53 BAF53A INO80K | DGsTLMEIDGDKGKQGGPtyyIDtNALRVPRENMEAIsPLK |
| P00338 | Y239 | Sugiyama | LDHA PIG19 | GtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVADL |
| P00558 | Y161 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL |
| P02786 | Y402 | Sugiyama | TFRC | KEIKILNIFGVIKGFVEPDHyVVVGAQRDAWGPGAAKSGVG |
| P04075 | T37 | Sugiyama | ALDOA ALDA | sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR |
| P04181 | Y48 | Sugiyama | OAT | VATKKtVQGPPtSDDIFEREyKyGAHNyHPLPVALERGKGI |
| P04406 | T99 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | ERDPsKIKWGDAGAEyVVEstGVFttMEKAGAHLQGGAKRV |
| P04406 | Y314 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK |
| P04406 | Y320 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____ |
| P04406 | Y94 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | ItIFQERDPsKIKWGDAGAEyVVEstGVFttMEKAGAHLQG |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05455 | Y104 | Sugiyama | SSB | EDKTKIRRsPsKPLPEVTDEyKNDVKNRsVYIKGFPtDAtL |
| P05787 | Y204 | Sugiyama | KRT8 CYK8 | NKRTEMENEFVLIKKDVDEAyMNKVELESRLEGLTDEINFL |
| P06733 | Y189 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | MILPVGAANFREAMRIGAEVyHNLKNVIKEKyGKDAtNVGD |
| P06733 | Y270 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV |
| P06733 | Y280 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD |
| P06733 | Y287 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | PsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKF |
| P06733 | Y44 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK |
| P06899 | Y41 | Sugiyama | H2BC11 H2BFR HIST1H2BJ | KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMG |
| P06899 | Y43 | Sugiyama | H2BC11 H2BFR HIST1H2BJ | QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMGIM |
| P07205 | Y161 | Sugiyama | PGK2 PGKB | KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL |
| P07237 | T101 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | KVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPKEytAGRE |
| P07237 | T117 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | RGyPtIKFFRNGDTASPKEytAGREADDIVNWLKKRTGPAA |
| P07237 | Y116 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | VRGyPtIKFFRNGDTASPKEytAGREADDIVNWLKKRTGPA |
| P07237 | Y94 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK |
| P07237 | Y99 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | LAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPKEytAG |
| P07355 | Y188 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT |
| P07437 | T107 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC |
| P07437 | Y50 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | IDPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEP |
| P07437 | Y51 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | DPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPG |
| P07711 | Y330 | Sugiyama | CTSL CTSL1 | GyVKMAKDRRNHCGIAsAAsyPtV_________________ |
| P07814 | Y1504 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | KPLCELQPGAKCVCGKNPAKyytLFGRsy____________ |
| P07814 | Y1505 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PLCELQPGAKCVCGKNPAKyytLFGRsy_____________ |
| P07814 | Y827 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK |
| P07900 | Y160 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | SAYLVAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPM |
| P07900 | Y197 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | GEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIGyP |
| P07900 | Y284 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI |
| P07900 | Y309 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF |
| P07900 | Y313 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG |
| P07900 | Y492 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DEMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLR |
| P07900 | Y493 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | EMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLRK |
| P08238 | Y155 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | SAYLVAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPI |
| P08238 | Y192 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIGyP |
| P08238 | Y276 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI |
| P08238 | Y301 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF |
| P08238 | Y305 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG |
| P08238 | Y472 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | sELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKE |
| P08238 | Y484 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR |
| P08238 | Y485 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVRK |
| P08238 | Y619 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR |
| P08621 | Y38 | Sugiyama | SNRNP70 RNPU1Z RPU1 SNRP70 U1AP1 | PIPYLPPLEKLPHEKHHNQPyCGIAPYIREFEDPRDAPPPT |
| P08708 | Y84 | Sugiyama | RPS17 RPS17L | GPVRGISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKE |
| P09234 | Y12 | Sugiyama | SNRPC | _________MPKFyCDyCDtyLtHDsPsVRKTHCSGRKHKE |
| P09234 | Y8 | Sugiyama | SNRPC | _____________MPKFyCDyCDtyLtHDsPsVRKTHCSGR |
| P09651 | Y244 | Sugiyama | HNRNPA1 HNRPA1 | GRGGFGGSRGGGGYGGSGDGyNGFGNDGGyGGGGPGYSGGS |
| P09651 | Y341 | Sugiyama | HNRNPA1 HNRPA1 | QSSNFGPMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGss |
| P09651 | Y347 | Sugiyama | HNRNPA1 HNRPA1 | PMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGssssssyG |
| P0CG38 | Y1062 | Sugiyama | POTEI | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P0CG39 | Y1025 | Sugiyama | POTEJ | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P10809 | Y223 | Sugiyama | HSPD1 HSP60 | DGKtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAy |
| P10809 | Y227 | Sugiyama | HSPD1 HSP60 | LNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLs |
| P10809 | Y243 | Sugiyama | HSPD1 HSP60 | yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P11142 | Y545 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | YKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKINDE |
| P11940 | Y194 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF |
| P12268 | Y509 | Sugiyama | IMPDH2 IMPD2 | KFEKRtssAQVEGGVHsLHsyEKRLF_______________ |
| P12270 | Y140 | Sugiyama | TPR | LEAEKRDLIRTNERLsQELEyLTEDVKRLNEKLKESNTTKG |
| P12277 | S129 | Sugiyama | CKB CKBB | DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG |
| P12277 | Y125 | Sugiyama | CKB CKBB | EHKTDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPH |
| P12814 | Y215 | Sugiyama | ACTN1 | KLRKDDPLTNLNTAFDVAEKyLDIPKMLDAEDIVGtARPDE |
| P12814 | Y378 | Sugiyama | ACTN1 | GRMVSDINNAWGCLEQVEKGyEEWLLNEIRRLERLDHLAEK |
| P12814 | Y842 | Sugiyama | ACTN1 | DTDTADQVMASFKILAGDKNyITMDELRRELPPDQAEyCIA |
| P12814 | Y859 | Sugiyama | ACTN1 | DKNyITMDELRRELPPDQAEyCIARMAPYTGPDSVPGALDY |
| P12956 | Y30 | Sugiyama | XRCC6 G22P1 | tEGDEEAEEEQEENLEAsGDyKYsGRDsLIFLVDASKAMFE |
| P13073 | Y38 | Sugiyama | COX4I1 COX4 | SVCVRAHESVVKsEDFsLPAyMDRRDHPLPEVAHVKHLSAS |
| P13639 | Y443 | Sugiyama | EEF2 EF2 | TGLKVRIMGPNytPGKKEDLyLKPIQRTILMMGRYVEPIED |
| P13639 | Y671 | Sugiyama | EEF2 EF2 | CFGPDGTGPNILTDITKGVQyLNEIKDSVVAGFQWATKEGA |
| P13667 | T449 | Sugiyama | PDIA4 ERP70 ERP72 | AATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLsE |
| P13667 | Y448 | Sugiyama | PDIA4 ERP70 ERP72 | RAATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLs |
| P13667 | Y458 | Sugiyama | PDIA4 ERP70 ERP72 | VLEVAKDFPEytFAIADEEDyAGEVKDLGLsEsGEDVNAAI |
| P13674 | Y282 | Sugiyama | P4HA1 P4HA | ASDDQSDQKTTPKKKGVAVDyLPERQKyEMLCRGEGIKMTP |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P14618 | Y148 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | GtAEVELKKGATLKITLDNAyMEKCDENILWLDYKNICKVV |
| P14625 | Y258 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | GNTLGRGTTITLVLKEEAsDyLELDTIKNLVKKYSQFINFP |
| P14625 | Y401 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | VTFKSILFVPTSAPRGLFDEyGsKKSDYIKLYVRRVFITDD |
| P14625 | Y429 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IKLYVRRVFITDDFHDMMPKyLNFVKGVVDsDDLPLNVsRE |
| P14625 | Y527 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | AKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAGsSRK |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14649 | Y86 | Sugiyama | MYL6B MLC1SA | LEEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVL |
| P14854 | Y34 | Sugiyama | COX6B1 COX6B | TAPFDSRFPNQNQTRNCWQNyLDFHRCQKAMTAKGGDIsVC |
| P14866 | T282 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | TLKIEYAKPTRLNVFKNDQDtWDyTNPNLsGQGDPGsNPNK |
| P15259 | Y92 | Sugiyama | PGAM2 PGAMM | DGTDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQV |
| P15311 | Y424 | Sugiyama | EZR VIL2 | ERQAVDQIKsQEQLAAELAEytAKIALLEEARRRKEDEVEE |
| P15880 | Y248 | Sugiyama | RPS2 RPS4 | GCtAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQE |
| P15880 | Y250 | Sugiyama | RPS2 RPS4 | tAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQEFt |
| P17066 | Y43 | Sugiyama | HSPA6 HSP70B' | FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL |
| P17676 | Y137 | Sugiyama | CEBPB TCF5 PP9092 | FLSDLFSDDYGGKNCKKPAEyGyVsLGRLGAAKGALHPGCF |
| P17676 | Y139 | Sugiyama | CEBPB TCF5 PP9092 | SDLFSDDYGGKNCKKPAEyGyVsLGRLGAAKGALHPGCFAP |
| P17812 | Y473 | Sugiyama | CTPS1 CTPS | RRtLFQTKNsVMRKLyGDADyLEERHRHRFEVNPVWKKCLE |
| P17948 | S1031 | Sugiyama | FLT1 FLT FRT VEGFR1 | EFLSSRKCIHRDLAARNILLsENNVVKICDFGLARDIyKNP |
| P17948 | S1125 | Sugiyama | FLT1 FLT FRT VEGFR1 | MDEDFCSRLREGMRMRAPEysTPEIyQIMLDCWHRDPKERP |
| P17948 | S1205 | Sugiyama | FLT1 FLT FRT VEGFR1 | STPAFSEDFFKESISAPKFNsGsSDDVRyVNAFKFMSLERI |
| P17948 | S1207 | Sugiyama | FLT1 FLT FRT VEGFR1 | PAFSEDFFKESISAPKFNsGsSDDVRyVNAFKFMSLERIKT |
| P17948 | S1288 | Sugiyama | FLT1 FLT FRT VEGFR1 | SLKIDLRVTSKSKESGLSDVsRPsFCHsSCGHVSEGKRRFt |
| P17948 | S1291 | Sugiyama | FLT1 FLT FRT VEGFR1 | IDLRVTSKSKESGLSDVsRPsFCHsSCGHVSEGKRRFtyDH |
| P17948 | S1295 | Sugiyama | FLT1 FLT FRT VEGFR1 | VTSKSKESGLSDVsRPsFCHsSCGHVSEGKRRFtyDHAELE |
| P17948 | T1308 | Sugiyama | FLT1 FLT FRT VEGFR1 | sRPsFCHsSCGHVSEGKRRFtyDHAELERKIACCSPPPDyN |
| P17948 | Y1048 | Sugiyama | FLT1 FLT FRT VEGFR1 | ILLsENNVVKICDFGLARDIyKNPDyVRKGDTRLPLKWMAP |
| P17948 | Y1053 | Sugiyama | FLT1 FLT FRT VEGFR1 | NNVVKICDFGLARDIyKNPDyVRKGDTRLPLKWMAPESIFD |
| P17948 | Y1124 | Sugiyama | FLT1 FLT FRT VEGFR1 | QMDEDFCSRLREGMRMRAPEysTPEIyQIMLDCWHRDPKER |
| P17948 | Y1130 | Sugiyama | FLT1 FLT FRT VEGFR1 | CSRLREGMRMRAPEysTPEIyQIMLDCWHRDPKERPRFAEL |
| P17948 | Y1169 | GPS6|SIGNOR|EPSD|PSP | FLT1 FLT FRT VEGFR1 | ELVEKLGDLLQANVQQDGKDyIPINAILTGNSGFTYSTPAF |
| P17948 | Y1213 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama | FLT1 FLT FRT VEGFR1 | FFKESISAPKFNsGsSDDVRyVNAFKFMSLERIKTFEELLP |
| P17948 | Y1242 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | FLT1 FLT FRT VEGFR1 | LERIKTFEELLPNATSMFDDyQGDSSTLLASPMLKRFTWTD |
| P17948 | Y1309 | GPS6|EPSD|Sugiyama | FLT1 FLT FRT VEGFR1 | RPsFCHsSCGHVSEGKRRFtyDHAELERKIACCSPPPDyNS |
| P17948 | Y1327 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | FLT1 FLT FRT VEGFR1 | FtyDHAELERKIACCSPPPDyNSVVLySTPPI_________ |
| P17948 | Y1333 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | FLT1 FLT FRT VEGFR1 | ELERKIACCSPPPDyNSVVLySTPPI_______________ |
| P17948 | Y920 | Sugiyama | FLT1 FLT FRT VEGFR1 | KQGGPLMVIVEYCKYGNLSNyLKSKRDLFFLNKDAALHMEP |
| P17980 | Y381 | Sugiyama | PSMC3 TBP1 | ARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQCKAVCV |
| P17987 | S544 | Sugiyama | TCP1 CCT1 CCTA | ILRIDDLIKLHPESKDDKHGsyEDAVHsGALND________ |
| P17987 | Y545 | Sugiyama | TCP1 CCT1 CCTA | LRIDDLIKLHPESKDDKHGsyEDAVHsGALND_________ |
| P18124 | Y155 | Sugiyama | RPL7 | IVEPYIAWGYPNLKsVNELIyKRGYGKINKKRIALtDNALI |
| P18124 | Y82 | Sugiyama | RPL7 | RQMYRTEIRMARMARKAGNFyVPAEPKLAFVIRIRGINGVS |
| P18206 | Y822 | Sugiyama | VCL | KAVAGNIsDPGLQKsFLDsGyRILGAVAKVREAFQPQEPDF |
| P18615 | Y133 | Sugiyama | NELFE RD RDBP | sIsADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEA |
| P18615 | Y170 | Sugiyama | NELFE RD RDBP | GEEAEGPGAGDGPPRsFDWGyEERSGAHSsAsPPRsRSRDR |
| P18621 | S5 | Sugiyama | RPL17 | ________________MVRysLDPENPtKsCKSRGSNLRVH |
| P18621 | Y4 | Sugiyama | RPL17 | _________________MVRysLDPENPtKsCKSRGSNLRV |
| P18669 | S134 | Sugiyama | PGAM1 PGAMA CDABP0006 | IWRRsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsCE |
| P18669 | Y142 | Sugiyama | PGAM1 PGAMA CDABP0006 | PPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIAR |
| P18669 | Y92 | Sugiyama | PGAM1 PGAMA CDABP0006 | DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV |
| P19105 | Y142 | Sugiyama | MYL12A MLCB MRLC3 RLC | LRELLttMGDRFtDEEVDELyREAPIDKKGNFNyIEFtRIL |
| P19105 | Y155 | Sugiyama | MYL12A MLCB MRLC3 RLC | DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____ |
| P19338 | Y462 | Sugiyama | NCL | AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs |
| P20042 | Y174 | Sugiyama | EIF2S2 EIF2B | DDGIsFsNQtGPAWAGSERDytyEELLNRVFNIMREKNPDM |
| P20618 | S151 | Sugiyama | PSMB1 PSC5 | PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA |
| P20618 | Y150 | Sugiyama | PSMB1 PSC5 | FPYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSAS |
| P20618 | Y158 | Sugiyama | PSMB1 PSC5 | IGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLD |
| P21980 | T368 | Sugiyama | TGM2 | QPGYEGWQALDPTPQEKsEGtyCCGPVPVRAIKEGDLstKy |
| P22234 | Y22 | Sugiyama | PAICS ADE2 AIRC PAIS | AtAEVLNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAG |
| P22392 | Y151 | Sugiyama | NME2 NM23B | SLWFKPEELVDyKSCAHDWVyE___________________ |
| P22626 | Y336 | Sugiyama | HNRNPA2B1 HNRPA2B1 | MKsGNFGGsRNMGGPyGGGNyGPGGsGGsGGyGGRsRy___ |
| P23193 | Y126 | Sugiyama | TCEA1 GTF2S TFIIS | EsTSsGNVsNRKDETNARDTyVsSFPRAPstsDsVRLKCRE |
| P23246 | Y488 | Sugiyama | SFPQ PSF | PMYQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQV |
| P23246 | Y490 | Sugiyama | SFPQ PSF | YQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQVEK |
| P23284 | Y119 | Sugiyama | PPIB CYPB | DFMIQGGDFtRGDGtGGKsIyGERFPDENFKLKHyGPGWVs |
| P23396 | S35 | Sugiyama | RPS3 OK/SW-cl.26 | GIFKAELNEFLtRELAEDGysGVEVRVtPTRTEIIILATRT |
| P23396 | Y34 | Sugiyama | RPS3 OK/SW-cl.26 | DGIFKAELNEFLtRELAEDGysGVEVRVtPTRTEIIILATR |
| P23434 | Y139 | Sugiyama | GCSH | EVTEINEALAENPGLVNKSCyEDGWLIKMtLsNPsELDELM |
| P23434 | Y164 | Sugiyama | GCSH | LIKMtLsNPsELDELMsEEAyEKYIKSIEE___________ |
| P23527 | Y41 | Sugiyama | H2BC17 H2BFH H2BFN HIST1H2BO | KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMG |
| P23527 | Y43 | Sugiyama | H2BC17 H2BFH H2BFN HIST1H2BO | QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMGIM |
| P23528 | T70 | Sugiyama | CFL1 CFL | EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE |
| P23528 | Y140 | Sugiyama | CFL1 CFL | SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs |
| P23528 | Y68 | Sugiyama | CFL1 CFL | ILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAt |
| P23588 | Y211 | Sugiyama | EIF4B | DsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDRYDsD |
| P24534 | Y18 | Sugiyama | EEF1B2 EEF1B EF1B | ___MGFGDLKsPAGLQVLNDyLADKSYIEGYVPsQADVAVF |
| P24752 | Y256 | Sugiyama | ACAT1 ACAT MAT | IPVtVtVKGQPDVVVKEDEEyKRVDFSKVPKLKTVFQKENG |
| P25205 | Y19 | Sugiyama | MCM3 | __MAGtVVLDDVELREAQRDyLDFLDDEEDQGIyQsKVREL |
| P25205 | Y32 | Sugiyama | MCM3 | LREAQRDyLDFLDDEEDQGIyQsKVRELIsDNQyRLIVNVN |
| P25208 | Y58 | Sugiyama | NFYB HAP3 | SMNDHEDTNGSKESFREQDIyLPIANVARIMKNAIPQTGKI |
| P25398 | Y127 | Sugiyama | RPS12 | sCVVVKDYGKESQAKDVIEEyFKCKK_______________ |
| P26196 | Y469 | Sugiyama | DDX6 HLR2 RCK | IEEQLGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP______ |
| P26196 | Y473 | Sugiyama | DDX6 HLR2 RCK | LGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP__________ |
| P26599 | Y127 | Sugiyama | PTBP1 PTB | ANTMVNYYTSVTPVLRGQPIyIQFsNHKELKtDSSPNQARA |
| P27348 | Y149 | Sugiyama | YWHAQ | LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG |
| P27348 | Y48 | Sugiyama | YWHAQ | AVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSIEQK |
| P27695 | Y128 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | LQELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGD |
| P27695 | Y45 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | KSKTAAKKNDKEAAGEGPALyEDPPDQKtsPsGKPAtLKIC |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P27797 | Y109 | Sugiyama | CALR CRTC | QTLVVQFTVKHEQNIDCGGGyVKLFPNSLDQTDMHGDSEYN |
| P27816 | Y47 | Sugiyama | MAP4 | AtLEAEAFDDVVGETVGKTDyIPLLDVDEKtGNsESKKKPC |
| P27824 | Y70 | Sugiyama | CANX | TAPPSSPKVTYKAPVPtGEVyFADsFDRGTLSGWILSKAKK |
| P28074 | Y171 | Sugiyama | PSMB5 LMPX MB1 X | GMGLSMGTMICGWDKRGPGLyyVDsEGNRISGATFSVGSGS |
| P29353 | Y427 | Sugiyama | SHC1 SHC SHCA | RKQMPPPPPCPGRELFDDPsyVNVQNLDKARQAVGGAGPPN |
| P29401 | Y481 | Sugiyama | TKT | AANTKGICFIRTsRPENAIIyNNNEDFQVGQAKVVLKSKDD |
| P29692 | Y26 | Sugiyama | EEF1D EF1D | LAHEKIWFDKFKYDDAERRFyEQMNGPVAGAsRQENGAsVI |
| P30043 | Y205 | Sugiyama | BLVRB FLR SCAN | MLRCLttDEyDGHstyPsHQyQ___________________ |
| P30085 | Y49 | Sugiyama | CMPK1 CMK CMPK UCK UMK UMPK | ytHLSAGELLRDERKNPDsQyGELIEKYIKEGKIVPVEITI |
| P30086 | Y106 | Sugiyama | PEBP1 PBP PEBP | HFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLHRyVWLVyE |
| P30086 | Y120 | Sugiyama | PEBP1 PBP PEBP | GtVLsDyVGsGPPKGtGLHRyVWLVyEQDRPLKCDEPILsN |
| P30086 | Y125 | Sugiyama | PEBP1 PBP PEBP | DyVGsGPPKGtGLHRyVWLVyEQDRPLKCDEPILsNRsGDH |
| P30086 | Y169 | Sugiyama | PEBP1 PBP PEBP | FKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK__ |
| P30086 | Y176 | Sugiyama | PEBP1 PBP PEBP | KKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK_________ |
| P30086 | Y64 | Sugiyama | PEBP1 PBP PEBP | tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW |
| P30101 | Y100 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | LAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRt |
| P30101 | Y115 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA |
| P30101 | Y264 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | CPHMTEDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVM |
| P30101 | Y265 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | PHMTEDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVMM |
| P30101 | Y269 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | EDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVMMVAKK |
| P30101 | Y356 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | FVMQEEFsRDGKALERFLQDyFDGNLKRyLKsEPIPESNDG |
| P30101 | Y67 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | LMLVEFFAPWCGHCKRLAPEyEAAAtRLKGIVPLAKVDCTA |
| P31153 | Y235 | Sugiyama | MAT2A AMS2 MATA2 | LDEMRDALKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGP |
| P31153 | Y242 | Sugiyama | MAT2A AMS2 MATA2 | LKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLt |
| P31943 | Y266 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst |
| P31946 | Y151 | Sugiyama | YWHAB | LsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLG |
| P31946 | Y21 | Sugiyama | YWHAB | MTMDKsELVQKAKLAEQAERyDDMAAAMKAVtEQGHELsNE |
| P31946 | Y213 | Sugiyama | YWHAB | LAKTAFDEAIAELDtLNEEsyKDstLIMQLLRDNLtLWtSE |
| P31946 | Y50 | Sugiyama | YWHAB | AVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK |
| P31947 | Y151 | Sugiyama | SFN HME1 | LAEVATGDDKKRIIDSARsAyQEAMDISKKEMPPTNPIRLG |
| P31947 | Y19 | Sugiyama | SFN HME1 | __MERASLIQKAKLAEQAERyEDMAAFMKGAVEKGEELsCE |
| P31947 | Y48 | Sugiyama | SFN HME1 | GAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsIEQK |
| P31948 | Y354 | Sugiyama | STIP1 | DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG |
| P31948 | Y41 | Sugiyama | STIP1 | DDALQCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDG |
| P32119 | Y115 | Sugiyama | PRDX2 NKEFB TDPX1 | GLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFIIDGK |
| P32929 | S61 | Sugiyama | CTH | ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA |
| P32969 | Y180 | Sugiyama | RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 | LIQQATTVKNKDIRKFLDGIyVsEKGtVQQADE________ |
| P33176 | Y516 | Sugiyama | KIF5B KNS KNS1 | EELAVNyDQKSQEVEDKTKEyELLSDELNQKsATLAsIDAE |
| P33316 | Y167 | Sugiyama | DUT | PPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDVGAG |
| P33778 | Y41 | Sugiyama | H2BC3 H2BFF HIST1H2BB | KAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKAMG |
| P33778 | Y43 | Sugiyama | H2BC3 H2BFF HIST1H2BB | QKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKAMGIM |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P34932 | Y30 | Sugiyama | HSPA4 APG2 HSPH2 | FQSCYVAVARAGGIETIANEysDRCtPACIsFGPKNRSIGA |
| P34932 | Y624 | Sugiyama | HSPA4 APG2 HSPH2 | MIMQDKLEKERNDAKNAVEEyVyEMRDKLSGEYEKFVSEDD |
| P34932 | Y626 | Sugiyama | HSPA4 APG2 HSPH2 | MQDKLEKERNDAKNAVEEyVyEMRDKLSGEYEKFVSEDDRN |
| P35268 | Y114 | Sugiyama | RPL22 | NNLRDWLRVVANSKESYELRyFQINQDEEEEEDED______ |
| P35609 | Y385 | Sugiyama | ACTN2 | GKMVSDIAGAWQRLEQAEKGyEEWLLNEIRRLERLEHLAEK |
| P36871 | Y476 | Sugiyama | PGM1 | GKQFSANDKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTD |
| P37108 | Y27 | Sugiyama | SRP14 | EQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGtVE |
| P37802 | Y192 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________ |
| P38646 | Y118 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK |
| P39019 | Y48 | Sugiyama | RPS19 | LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P40261 | Y11 | Sugiyama | NNMT | __________MESGFTSKDTyLSHFNPRDYLEKYYKFGSRH |
| P40429 | Y149 | Sugiyama | RPL13A | LKPTRKFAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYR |
| P40926 | Y80 | Sugiyama | MDH2 | HtPGVAADLsHIEtKAAVKGyLGPEQLPDCLKGCDVVVIPA |
| P41567 | Y30 | Sugiyama | EIF1 SUI1 | FDPFADAsKGDDLLPAGTEDyIHIRIQQRNGRKtLttVQGI |
| P42025 | Y33 | Sugiyama | ACTR1B CTRN2 | VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALE |
| P42025 | Y38 | Sugiyama | ACTR1B CTRN2 | SGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALEGDLFI |
| P42224 | Y170 | Sugiyama | STAT1 | KDKVMCIEHEIKsLEDLQDEyDFKCKTLQNREHETNGVAKS |
| P43243 | Y202 | Sugiyama | MATR3 KIAA0723 | RHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDD |
| P43490 | Y34 | Sugiyama | NAMPT PBEF PBEF1 | ATDSYKVTHYKQYPPNTSKVysyFECREKKTENSKLRKVKY |
| P46063 | S63 | Sugiyama | RECQL RECQ1 RECQL1 | TKKIKQCLEDsDAGAsNEyDssPAAWNKEDFPWSGKVKDIL |
| P46063 | Y61 | Sugiyama | RECQL RECQ1 RECQL1 | VLTKKIKQCLEDsDAGAsNEyDssPAAWNKEDFPWSGKVKD |
| P46777 | Y207 | Sugiyama | RPL5 MSTP030 | sKEFNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyI |
| P46777 | Y210 | Sugiyama | RPL5 MSTP030 | FNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyIKNs |
| P46777 | Y219 | Sugiyama | RPL5 MSTP030 | IMGQNVADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEM |
| P46777 | Y240 | Sugiyama | RPL5 MSTP030 | KKQFsQyIKNsVtPDMMEEMyKKAHAAIRENPVyEKKPKKE |
| P46778 | T29 | Sugiyama | RPL21 | RGTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQ |
| P46778 | Y156 | Sugiyama | RPL21 | REAHFVRTNGKEPELLEPIPyEFMA________________ |
| P47224 | Y114 | Sugiyama | RABIF MSS4 RASGRF3 | CADCEIGPIGWHCLDDKNSFyVALERVSHE___________ |
| P47756 | Y232 | Sugiyama | CAPZB | NIGRLVEDMENKIRstLNEIyFGKTKDIVNGLRSVQTFADK |
| P47813 | Y35 | Sugiyama | EIF1AX EIF1A EIF4C | GKNENESEKRELVFKEDGQEyAQVIKMLGNGRLEAMCFDGV |
| P47914 | Y98 | Sugiyama | RPL29 | PKEVKPKIPKGVSRKLDRLAyIAHPKLGKRARARIAKGLRL |
| P48643 | Y274 | Sugiyama | CCT5 CCTE KIAA0098 | PFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQQIKE |
| P48741 | Y43 | Sugiyama | HSPA7 HSP70B | FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL |
| P49327 | Y2462 | Sugiyama | FASN FAS | NVMLLRAKtGGAyGEDLGADyNLsQVCDGKVsVHVIEGDHR |
| P50402 | Y94 | Sugiyama | EMD EDMD STA | yDLPKKEDALLyQsKGyNDDyyEEsyFTTRTyGEPEsAGPS |
| P50402 | Y99 | Sugiyama | EMD EDMD STA | KEDALLyQsKGyNDDyyEEsyFTTRTyGEPEsAGPSRAVRQ |
| P50502 | Y185 | Sugiyama | ST13 AAG2 FAM10A1 HIP SNC6 | NAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEAAHDL |
| P50990 | Y30 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | GFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTTRTAYGPN |
| P50991 | Y269 | Sugiyama | CCT4 CCTD SRB | IQFCLSAPKTDMDNQIVVSDyAQMDRVLREERAYILNLVKQ |
| P51116 | Y614 | Sugiyama | FXR2 FMR1L2 | RGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLERTKPs |
| P52565 | Y156 | Sugiyama | ARHGDIA GDIA1 | GVKIDKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYs |
| P52597 | Y266 | Sugiyama | HNRNPF HNRPF | ySGLSDGYGFTTDLFGRDLsyCLsGMyDHRYGDsEFtVQsT |
| P52948 | Y848 | Sugiyama | NUP98 ADAR2 | PTDKTSRCLIKsPDRLADINyEGRLEAVSRKQGAQFKEyRP |
| P53634 | Y438 | Sugiyama | CTSC CPPI | SGMDYWIVKNsWGtGWGENGyFRIRRGtDECAIEsIAVAAt |
| P53999 | S118 | Sugiyama | SUB1 PC4 RPO2TC1 | PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________ |
| P54105 | Y214 | Sugiyama | CLNS1A CLCI ICLN | QsVssQYNMAGVRtEDsIRDyEDGMEVDttPtVAGQFEDAD |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P55060 | Y369 | Sugiyama | CSE1L CAS XPO2 | VPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAACDL |
| P55209 | Y106 | Sugiyama | NAP1L1 NRP | VKCAQIEAKFyEEVHDLERKyAVLyQPLFDKRFEIINAIYE |
| P55209 | Y110 | Sugiyama | NAP1L1 NRP | QIEAKFyEEVHDLERKyAVLyQPLFDKRFEIINAIYEPTEE |
| P55209 | Y66 | Sugiyama | NAP1L1 NRP | PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV |
| P55263 | Y130 | Sugiyama | ADK | DKFGEILKRKAAEAHVDAHyyEQNEQPTGTCAACITGDNRS |
| P55795 | Y266 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst |
| P57053 | Y41 | Sugiyama | H2BC12L H2BFS H2BS1 | KAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| P57053 | Y43 | Sugiyama | H2BC12L H2BFS H2BS1 | QKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| P58876 | Y41 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| P58876 | Y43 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| P60174 | Y209 | Sugiyama | TPI1 TPI | LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG |
| P60228 | Y445 | Sugiyama | EIF3E EIF3S6 INT6 | KLNQNSRSEAPNWAtQDsGFy____________________ |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60660 | Y29 | Sugiyama | MYL6 | TAEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVL |
| P60660 | Y86 | Sugiyama | MYL6 | DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG |
| P60660 | Y89 | Sugiyama | MYL6 | HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI |
| P60709 | Y198 | Sugiyama | ACTB | LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60709 | Y362 | Sugiyama | ACTB | GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P60900 | Y159 | Sugiyama | PSMA6 PROS27 | ILIGIDEEQGPQVYKCDPAGyyCGFKATAAGVKQtEstsFL |
| P60900 | Y160 | Sugiyama | PSMA6 PROS27 | LIGIDEEQGPQVYKCDPAGyyCGFKATAAGVKQtEstsFLE |
| P61024 | Y19 | Sugiyama | CKS1B CKS1 PNAS-143 PNAS-16 | __MSHKQIyysDKyDDEEFEyRHVMLPKDIAKLVPKTHLMs |
| P61024 | Y7 | Sugiyama | CKS1B CKS1 PNAS-143 PNAS-16 | ______________MSHKQIyysDKyDDEEFEyRHVMLPKD |
| P61081 | Y172 | Sugiyama | UBE2M UBC12 | VLQNNRRLFEQNVQRSMRGGyIGstyFERCLK_________ |
| P61081 | Y177 | Sugiyama | UBE2M UBC12 | RRLFEQNVQRSMRGGyIGstyFERCLK______________ |
| P61158 | S232 | Sugiyama | ACTR3 ARP3 | EVGIPPEQSLETAKAVKERysyVCPDLVKEFNKYDTDGSKW |
| P61158 | Y231 | Sugiyama | ACTR3 ARP3 | REVGIPPEQSLETAKAVKERysyVCPDLVKEFNKYDTDGSK |
| P61163 | Y33 | Sugiyama | ACTR1A CTRN1 | VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALE |
| P61163 | Y38 | Sugiyama | ACTR1A CTRN1 | SGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALEGDIFI |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61247 | T246 | Sugiyama | RPS3A FTE1 MFTL | GKLMELHGEGsssGKAtGDEtGAKVERADGyEPPVQEsV__ |
| P61247 | Y256 | Sugiyama | RPS3A FTE1 MFTL | sssGKAtGDEtGAKVERADGyEPPVQEsV____________ |
| P61247 | Y31 | Sugiyama | RPS3A FTE1 MFTL | KGGKKGAKKKVVDPFSKKDWyDVKAPAMFNIRNIGKTLVTR |
| P61313 | Y6 | Sugiyama | RPL15 EC45 TCBAP0781 | _______________MGAYKyIQELWRKKQSDVMRFLLRVR |
| P61353 | S39 | Sugiyama | RPL27 | SGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVTAAMGK |
| P61353 | Y85 | Sugiyama | RPL27 | RSKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPA |
| P61604 | T79 | Sugiyama | HSPE1 | EIQPVsVKVGDKVLLPEyGGtKVVLDDKDyFLFRDGDILGK |
| P61604 | Y100 | Sugiyama | HSPE1 | KVVLDDKDyFLFRDGDILGKyVD__________________ |
| P61604 | Y88 | Sugiyama | HSPE1 | GDKVLLPEyGGtKVVLDDKDyFLFRDGDILGKyVD______ |
| P61978 | Y72 | Sugiyama | HNRNPK HNRPK | KNAGAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISA |
| P61981 | S215 | Sugiyama | YWHAG | HLAKtAFDDAIAELDtLNEDsyKDstLIMQLLRDNLtLWts |
| P61981 | Y20 | Sugiyama | YWHAG | _MVDREQLVQKARLAEQAERyDDMAAAMKNVtELNEPLsNE |
| P61981 | Y49 | Sugiyama | YWHAG | NVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK |
| P62081 | Y177 | Sugiyama | RPS7 | HLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEFQL___ |
| P62191 | Y184 | Sugiyama | PSMC1 | MDDTDPLVTVMKVEKAPQETyADIGGLDNQIQEIKESVELP |
| P62191 | Y439 | Sugiyama | PSMC1 | FKKSKENVLyKKQEGtPEGLyL___________________ |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62249 | Y115 | Sugiyama | RPS16 | YYQKYVDEASKKEIKDILIQyDRtLLVADPRRCESKKFGGP |
| P62258 | Y152 | Sugiyama | YWHAE | LAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLG |
| P62258 | Y214 | Sugiyama | YWHAE | LAKAAFDDAIAELDtLsEEsyKDstLIMQLLRDNLtLWtsD |
| P62258 | Y49 | Sugiyama | YWHAE | KVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssIEQK |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62269 | Y95 | Sugiyama | RPS18 D6S218E | RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK |
| P62273 | Y7 | Sugiyama | RPS29 | ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR |
| P62277 | Y18 | Sugiyama | RPS13 | ___MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVKEQIy |
| P62280 | Y55 | Sugiyama | RPS11 | RYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILsG |
| P62495 | Y345 | Sugiyama | ETF1 ERF1 RF1 SUP45L1 | NLDIMRYVLHCQGTEEEKILyLTPEQEKDKSHFTDKETGQE |
| P62633 | Y120 | Sugiyama | CNBP RNF163 ZNF9 | NCGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRC |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62750 | Y144 | Sugiyama | RPL23A | VNtLIRPDGEKKAYVRLAPDyDALDVANKIGII________ |
| P62750 | Y74 | Sugiyama | RPL23A | LRRQPKYPRKSAPRRNKLDHyAIIKFPLTTEsAMKKIEDNN |
| P62753 | Y156 | Sugiyama | RPS6 OK/SW-cl.2 | KRASRIRKLFNLsKEDDVRQyVVRKPLNKEGKKPRTKAPKI |
| P62807 | Y41 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | KAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMG |
| P62807 | Y43 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | QKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| P62826 | Y146 | Sugiyama | RAN ARA24 OK/SW-cl.81 | IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR |
| P62826 | Y147 | Sugiyama | RAN ARA24 OK/SW-cl.81 | KDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARK |
| P62847 | Y76 | Sugiyama | RPS24 | FVFGFRTHFGGGKttGFGMIyDsLDyAKKNEPKHRLARHGL |
| P62847 | Y81 | Sugiyama | RPS24 | RTHFGGGKttGFGMIyDsLDyAKKNEPKHRLARHGLYEKKK |
| P62888 | Y62 | Sugiyama | RPL30 | KAKLVILANNCPALRKsEIEyyAMLAKtGVHHysGNNIELG |
| P62888 | Y63 | Sugiyama | RPL30 | AKLVILANNCPALRKsEIEyyAMLAKtGVHHysGNNIELGt |
| P62899 | Y108 | Sugiyama | RPL31 | LSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN___ |
| P62899 | Y25 | Sugiyama | RPL31 | KKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRA |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | T135 | Sugiyama | RPL8 | CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62942 | Y27 | Sugiyama | FKBP1A FKBP1 FKBP12 | tIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPF |
| P62979 | Y148 | Sugiyama | RPS27A UBA80 UBCEP1 | AGVFMAsHFDRHyCGKCCLtyCFNKPEDK____________ |
| P63096 | Y154 | SIGNOR | GNAI1 | SGVQACFNRSREYQLNDSAAyyLNDLDRIAQPNYIPTQQDV |
| P63096 | Y155 | SIGNOR | GNAI1 | GVQACFNRSREYQLNDSAAyyLNDLDRIAQPNYIPTQQDVL |
| P63096 | Y320 | SIGNOR | GNAI1 | AAYIQCQFEDLNKRKDTKEIytHFTCATDTKNVQFVFDAVT |
| P63104 | Y149 | Sugiyama | YWHAZ | LAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLG |
| P63104 | Y211 | Sugiyama | YWHAZ | LAKtAFDEAIAELDtLsEEsyKDstLIMQLLRDNLtLWtsD |
| P63104 | Y48 | Sugiyama | YWHAZ | sVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssIEQK |
| P63173 | Y41 | Sugiyama | RPL38 | KSVKIKKNKDNVKFKVRCSRyLytLVItDKEKAEKLKQSLP |
| P63173 | Y43 | Sugiyama | RPL38 | VKIKKNKDNVKFKVRCSRyLytLVItDKEKAEKLKQSLPPG |
| P63220 | Y53 | Sugiyama | RPS21 | QMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRLA |
| P63261 | Y198 | Sugiyama | ACTG1 ACTG | LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63261 | Y362 | Sugiyama | ACTG1 ACTG | GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P67809 | S209 | Sugiyama | YBX1 NSEP1 YB1 | RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ |
| P67809 | Y196 | Sugiyama | YBX1 NSEP1 YB1 | sAPEGQAQQRRPyRRRRFPPyyMRRPYGRRPQysNPPVQGE |
| P67809 | Y197 | Sugiyama | YBX1 NSEP1 YB1 | APEGQAQQRRPyRRRRFPPyyMRRPYGRRPQysNPPVQGEV |
| P67809 | Y72 | Sugiyama | YBX1 NSEP1 YB1 | KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68104 | Y29 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68363 | Y432 | Sugiyama | TUBA1B | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| P68363 | Y451 | Sugiyama | TUBA1B | DyEEVGVDsVEGEGEEEGEEy____________________ |
| P68400 | Y323 | Sugiyama | CSNK2A1 CK2A1 | KLLRYDHQSRLTAREAMEHPyFytVVKDQARMGSSSMPGGS |
| P68400 | Y325 | Sugiyama | CSNK2A1 CK2A1 | LRYDHQSRLTAREAMEHPyFytVVKDQARMGSSSMPGGStP |
| P83731 | Y11 | Sugiyama | RPL24 | __________MKVELCsFsGyKIYPGHGRRYARTDGKVFQF |
| P84098 | T29 | Sugiyama | RPL19 | RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL |
| P98082 | Y38 | Sugiyama | DAB2 DOC2 | AAPKAPsKKEKKKGPEKTDEyLLARFKGDGVKYKAKLIGID |
| Q00059 | Y165 | Sugiyama | TFAM TCF6 TCF6L2 | KKKELTLLGKPKRPRsAYNVyVAERFQEAKGDsPQEKLKTV |
| Q00169 | Y140 | Sugiyama | PITPNA PITPN | GTQENVHKLEPEAWKHVEAVyIDIADRSQVLSKDYKAEEDP |
| Q00839 | Y257 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | QKGGDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVE |
| Q00839 | Y260 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED |
| Q01105 | Y146 | Sugiyama | SET | tEFEDIKsGyRIDFyFDENPyFENKVLSKEFHLNEsGDPss |
| Q01130 | Y44 | Sugiyama | SRSF2 SFRS2 | RtsPDtLRRVFEKYGRVGDVyIPRDRYTKESRGFAFVRFHD |
| Q02878 | T118 | Sugiyama | RPL6 TXREB1 | GDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQHVR |
| Q02878 | Y115 | Sugiyama | RPL6 TXREB1 | PVGGDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQ |
| Q02878 | Y116 | Sugiyama | RPL6 TXREB1 | VGGDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQH |
| Q02878 | Y216 | Sugiyama | RPL6 TXREB1 | AtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIFDtE |
| Q04760 | Y136 | SIGNOR|PSP | GLO1 | HNGNsDPRGFGHIGIAVPDVySACKRFEELGVKFVKKPDDG |
| Q04837 | Y73 | Sugiyama | SSBP1 SSBP | PVTIFSLATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPG |
| Q04917 | Y154 | Sugiyama | YWHAH YWHA1 | LAEVASGEKKNsVVEAsEAAyKEAFEISKEQMQPTHPIRLG |
| Q04917 | Y49 | Sugiyama | YWHAH YWHA1 | AVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSIEQK |
| Q05639 | Y29 | Sugiyama | EEF1A2 EEF1AL STN | NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM |
| Q06830 | Y116 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK |
| Q07666 | Y145 | Sugiyama | KHDRBS1 SAM68 | LtAEIEKIQKGDSKKDDEENyLDLFsHKNMKLKERVLIPVK |
| Q07955 | Y37 | Sugiyama | SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 | RIyVGNLPPDIRtKDIEDVFyKYGAIRDIDLKNRRGGPPFA |
| Q07960 | Y65 | Sugiyama | ARHGAP1 CDC42GAP RHOGAP1 | DDsKsssPELVtHLKWDDPyyDIARHQIVEVAGDDKYGRKI |
| Q08043 | Y229 | Sugiyama | ACTN3 | KLRKDDPIGNLNTAFEVAEKyLDIPKMLDAEDIVNtPKPDE |
| Q08211 | Y68 | Sugiyama | DHX9 DDX9 LKP NDH2 | MGNSTNKKDAQSNAARDFVNyLVRINEIKsEEVPAFGVAsP |
| Q08J23 | Y51 | Sugiyama | NSUN2 SAKI TRM4 | EAGWEGGyPEIVKENKLFEHyyQELKIVPEGEWGQFMDALR |
| Q08J23 | Y52 | Sugiyama | NSUN2 SAKI TRM4 | AGWEGGyPEIVKENKLFEHyyQELKIVPEGEWGQFMDALRE |
| Q09028 | Y154 | Sugiyama | RBBP4 RBAP48 | PQNPCIIATKtPssDVLVFDyTKHPsKPDPsGECNPDLRLR |
| Q13017 | Y1109 | Sugiyama | ARHGAP5 RHOGAP5 | DNyAEPIDTIFKQKGYsDEIyVVPDDsQNRIKIRNsFVNNt |
| Q13098 | Y172 | Sugiyama | GPS1 COPS1 CSN1 | YKGNSIKESIRRGHDDLGDHyLDCGDLSNALKCYSRARDYC |
| Q13242 | Y17 | Sugiyama | SRSF9 SFRS9 SRP30C | ____MsGWADERGGEGDGRIyVGNLPTDVREKDLEDLFyKY |
| Q13263 | Y133 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | TVVDCPVCKQQCFSKDIVENyFMRDsGsKAATDAQDANQCC |
| Q13263 | Y242 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | ESCDTLTCRDCQLNAHKDHQyQFLEDAVRNQRKLLAsLVKR |
| Q13263 | Y517 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | LtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATGQPGtA |
| Q13303 | Y270 | Sugiyama | KCNAB2 KCNA2B KCNK2 | IVSGKYDSGIPPYSRAsLKGyQWLKDKILSEEGRRQQAKLK |
| Q13310 | Y194 | Sugiyama | PABPC4 APP1 PABP4 | KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF |
| Q13405 | Y45 | Sugiyama | MRPL49 C11orf4 NOF1 OK/SW-cl.67 | LLSQTQGPPDYPRFVEsVDEyQFVERLLPATRIPDPPKHEH |
| Q13435 | Y591 | Sugiyama | SF3B2 SAP145 | LHDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSD |
| Q13435 | Y592 | Sugiyama | SF3B2 SAP145 | HDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSDE |
| Q13442 | S19 | Sugiyama | PDAP1 HASPP28 | __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE |
| Q13442 | Y17 | Sugiyama | PDAP1 HASPP28 | ____MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREE |
| Q13442 | Y70 | Sugiyama | PDAP1 HASPP28 | DPKKEKKsLDsDEsEDEEDDyQQKRKGVEGLIDIENPNRVA |
| Q13509 | T107 | Sugiyama | TUBB3 TUBB4 | PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC |
| Q13561 | Y6 | Sugiyama | DCTN2 DCTN50 | _______________MADPKyADLPGIARNEPDVYETSDLP |
| Q13573 | Y260 | Sugiyama | SNW1 SKIIP SKIP | KEQQEWKIPPCISNWKNAKGytIPLDKRLAADGRGLQTVHI |
| Q13642 | Y117 | Sugiyama | FHL1 SLIM1 | DsPKCKGCFKAIVAGDQNVEyKGtVWHKDCFTCSNCKQVIG |
| Q13765 | Y120 | Sugiyama | NACA HSD48 | KNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAAA |
| Q13885 | T107 | Sugiyama | TUBB2A TUBB2 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q14152 | Y697 | Sugiyama | EIF3A EIF3S10 KIAA0139 | LEKEKKELQERLKNQEKKIDyFERAKRLEEIPLIKSAYEEQ |
| Q14157 | Y858 | Sugiyama | UBAP2L KIAA0144 NICE4 | PFPtPttPLtGRDGsLAsNPysGDLtKFGRGDASSPAPATT |
| Q14257 | Y303 | Sugiyama | RCN2 ERC55 | LsEEEILENPDLFLtsEAtDyGRQLHDDyFyHDEL______ |
| Q14257 | Y311 | Sugiyama | RCN2 ERC55 | NPDLFLtsEAtDyGRQLHDDyFyHDEL______________ |
| Q14257 | Y313 | Sugiyama | RCN2 ERC55 | DLFLtsEAtDyGRQLHDDyFyHDEL________________ |
| Q14257 | Y39 | Sugiyama | RCN2 ERC55 | AAGAGKAEELHyPLGERRsDyDREALLGVQEDVDEyVKLGH |
| Q14257 | Y54 | Sugiyama | RCN2 ERC55 | ERRsDyDREALLGVQEDVDEyVKLGHEEQQKRLQAIIKKID |
| Q14444 | Y99 | Sugiyama | CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 | QERMNKGERLNQDQLDAVsKyQEVtNNLEFAKELQRsFMAL |
| Q14568 | Y160 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | SAYLVAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERM |
| Q14568 | Y283 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI |
| Q14671 | Y83 | Sugiyama | PUM1 KIAA0099 PUMH1 | SPVPGSIGVAGRsQDDAMVDyFFQRQHGEQLGGGGsGGGGy |
| Q14696 | Y58 | Sugiyama | MESD KIAA0081 MESDC2 MESDM UNQ1911/PRO4369 | PGTPDESTPPPRKKKKDIRDyNDADMARLLEQWEKDDDIEE |
| Q14697 | Y60 | Sugiyama | GANAB G2AN KIAA0088 | tCEEssFCKRQRsIRPGLsPyRALLDSLQLGPDSLTVHLIH |
| Q15056 | Y101 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | FKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRKQ |
| Q15181 | Y169 | Sugiyama | PPA1 IOPPP PP | EGETDWKVIAINVDDPDAANyNDINDVKRLKPGYLEATVDW |
| Q15181 | Y17 | Sugiyama | PPA1 IOPPP PP | ____MSGFSTEERAAPFsLEyRVFLKNEKGQyIsPFHDIPI |
| Q15287 | Y205 | Sugiyama | RNPS1 LDC2 | GKIKMIDMPVERMHPHLSKGyAyVEFENPDEAEKALKHMDG |
| Q15287 | Y207 | Sugiyama | RNPS1 LDC2 | IKMIDMPVERMHPHLSKGyAyVEFENPDEAEKALKHMDGGQ |
| Q15293 | T144 | Sugiyama | RCN1 RCN | WKDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtF |
| Q15293 | Y115 | Sugiyama | RCN1 RCN | GDGFVttEELKtWIKRVQKRyIFDNVAKVWKDYDRDKDDKI |
| Q15293 | Y145 | Sugiyama | RCN1 RCN | KDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFK |
| Q15293 | Y147 | Sugiyama | RCN1 RCN | YDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFKKM |
| Q15293 | Y148 | Sugiyama | RCN1 RCN | DRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFKKML |
| Q15293 | Y278 | Sugiyama | RCN1 RCN | LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE |
| Q15369 | Y18 | Sugiyama | ELOC TCEB1 | ___MDGEEKtyGGCEGPDAMyVKLISSDGHEFIVKREHALt |
| Q15424 | Y723 | Sugiyama | SAFB HAP HET SAFB1 | EQERRPAVRRPYDLDRRDDAyWPEAKRAALDERYHSDFNRQ |
| Q15427 | Y16 | Sugiyama | SF3B4 SAP49 | _____MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFLQA |
| Q15459 | Y456 | Sugiyama | SF3A1 SAP114 | PRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAERRtDI |
| Q15527 | Y123 | Sugiyama | SURF2 | GRRYQRALCKYEECQKQGVEyVPACLVHRRRRREDQMDGDG |
| Q15642 | Y590 | Sugiyama | TRIP10 CIP4 STOT STP | MEEDKGDGWTRVRRKEGGEGyVPtsyLRVTLN_________ |
| Q15642 | Y595 | Sugiyama | TRIP10 CIP4 STOT STP | GDGWTRVRRKEGGEGyVPtsyLRVTLN______________ |
| Q15650 | Y345 | Sugiyama | TRIP4 RQT4 | KVTIDFAGRKILEEENsLAEyHSRLDETIQAIANGTLNQPL |
| Q16576 | Y153 | Sugiyama | RBBP7 RBAP46 | PQNPHIIATKtPssDVLVFDyTKHPAKPDPsGECNPDLRLR |
| Q16719 | S443 | Sugiyama | KYNU | VVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAET |
| Q16719 | Y441 | Sugiyama | KYNU | RGVVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsA |
| Q16719 | Y448 | Sugiyama | KYNU | RNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAETKN___ |
| Q16719 | Y47 | Sugiyama | KYNU | ERVALHLDEEDKLRHFRECFyIPKIQDLPPVDLSLVNKDEN |
| Q16719 | Y86 | Sugiyama | KYNU | ENAIYFLGNSLGLQPKMVKtyLEEELDKWAKIAAYGHEVGK |
| Q16778 | Y41 | Sugiyama | H2BC21 H2BFQ HIST2H2BE | KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKAMG |
| Q16778 | Y43 | Sugiyama | H2BC21 H2BFQ HIST2H2BE | QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKAMGIM |
| Q53H82 | Y121 | Sugiyama | LACTB2 CGI-83 | IKKLPRNPQREEIIGNGEQQyVyLKDGDVIKTEGATLRVLY |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q58FF3 | Y58 | Sugiyama | HSP90B2P GRP94B GRP94P1 TRAP1 | VTFKSILFVPTFVPRGLFDEyGsKKSDYIKLYVRCVFITDD |
| Q58FF6 | Y167 | Sugiyama | HSP90AB4P | GEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIGCL |
| Q58FF7 | Y171 | Sugiyama | HSP90AB3P HSP90BC | GEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIGyP |
| Q58FF7 | Y492 | Sugiyama | HSP90AB3P HSP90BC | TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR |
| Q58FF8 | Y198 | Sugiyama | HSP90AB2P HSP90BB | DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI |
| Q58FF8 | Y260 | Sugiyama | HSP90AB2P HSP90BB | VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW |
| Q58FF8 | Y261 | Sugiyama | HSP90AB2P HSP90BB | RYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVWK |
| Q58FG0 | Y177 | Sugiyama | HSP90AA5P HSP90AE | GQLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQ |
| Q58FG0 | Y178 | Sugiyama | HSP90AA5P HSP90AE | QLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQK |
| Q5JTH9 | Y1251 | Sugiyama | RRP12 KIAA0690 | AEYKAKKAKGDVKKKGRPDPyAyIPLNRSKLNRRKKMKLQG |
| Q5JTH9 | Y1253 | Sugiyama | RRP12 KIAA0690 | YKAKKAKGDVKKKGRPDPyAyIPLNRSKLNRRKKMKLQGQF |
| Q5QNW6 | Y41 | Sugiyama | H2BC18 HIST2H2BF | KVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q5QNW6 | Y43 | Sugiyama | H2BC18 HIST2H2BF | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q5T035 | Y67 | Sugiyama | FAM120A2P C9orf129 | SEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERSLPIN |
| Q5VTE0 | Y29 | Sugiyama | EEF1A1P5 EEF1AL3 | NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM |
| Q5VV41 | Y216 | Sugiyama | ARHGEF16 EPHEXIN4 NBR | KKTLGRKRGHKGsFKDDPQLyQEIQERGLNtsQEsDDDILD |
| Q6DN03 | Y41 | Sugiyama | H2BC20P HIST2H2BC | KAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMG |
| Q6DN03 | Y43 | Sugiyama | H2BC20P HIST2H2BC | QKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMGIM |
| Q6DRA6 | Y41 | Sugiyama | H2BC19P HIST2H2BD | KAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMG |
| Q6DRA6 | Y43 | Sugiyama | H2BC19P HIST2H2BD | QKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMGIM |
| Q6S8J3 | Y1062 | Sugiyama | POTEE A26C1A POTE2 | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q6WKZ4 | Y1254 | Sugiyama | RAB11FIP1 RCP | VLKQKETISKKEFQVRELEDyIDNLLVRVMEETPNILRIPT |
| Q71U36 | Y432 | Sugiyama | TUBA1A TUBA3 | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| Q71U36 | Y451 | Sugiyama | TUBA1A TUBA3 | DyEEVGVDsVEGEGEEEGEEy____________________ |
| Q7L804 | Y480 | Sugiyama | RAB11FIP2 KIAA0941 | LVKHKELLRRKDTHIRELEDyIDNLLVRVMEETPSILRVPY |
| Q86U42 | Y217 | Sugiyama | PABPN1 PAB2 PABP2 | sVNRVTILCDKFSGHPKGFAyIEFSDKEsVRTSLALDEsLF |
| Q86UP2 | S156 | Sugiyama | KTN1 CG1 KIAA0004 | SKIPGKKVEPVPVtKQPtPPsEAAAsKKKPGQKKSKNGSDD |
| Q86UP2 | S161 | Sugiyama | KTN1 CG1 KIAA0004 | KKVEPVPVtKQPtPPsEAAAsKKKPGQKKSKNGSDDQDKKV |
| Q86UP2 | T153 | Sugiyama | KTN1 CG1 KIAA0004 | SDASKIPGKKVEPVPVtKQPtPPsEAAAsKKKPGQKKSKNG |
| Q86V81 | Y250 | Sugiyama | ALYREF ALY BEF THOC4 | AGRNSKQQLsAEELDAQLDAyNARMDts_____________ |
| Q86VS8 | Y171 | Sugiyama | HOOK3 | MTAIQELMSKEsPVSAGNDAyVDLDRQLKKTTEELNEALSA |
| Q8IWX8 | Y894 | Sugiyama | CHERP DAN26 SCAF6 | GDVRDKWDQYKGVGVALDDPyENyRRNKsysFIARMKARDE |
| Q8IWX8 | Y897 | Sugiyama | CHERP DAN26 SCAF6 | RDKWDQYKGVGVALDDPyENyRRNKsysFIARMKARDECK_ |
| Q8IWX8 | Y903 | Sugiyama | CHERP DAN26 SCAF6 | YKGVGVALDDPyENyRRNKsysFIARMKARDECK_______ |
| Q8N0Y7 | S134 | Sugiyama | PGAM4 PGAM3 | IWRRsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSYE |
| Q8N0Y7 | Y92 | Sugiyama | PGAM4 PGAM3 | DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV |
| Q8N257 | Y41 | Sugiyama | H2BC26 H2BU1 HIST3H2BB | KAQKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKAMG |
| Q8N257 | Y43 | Sugiyama | H2BC26 H2BU1 HIST3H2BB | QKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKAMGIM |
| Q8N7H5 | Y322 | Sugiyama | PAF1 PD2 | KASKGyEENyFFIFREGDGVyyNELETRVRLSKRRAKAGVQ |
| Q8NBS9 | Y251 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | ALGLEHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDG |
| Q8NBS9 | Y289 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | RDGKKVDQYKGKRDLEsLREyVEsQLQRTETGATETVTPSE |
| Q8ND56 | Y455 | Sugiyama | LSM14A C19orf13 FAM61A RAP55 RAP55A | RGFRGGFRGGRGGREFADFEyRKTTAFGP____________ |
| Q8NFI4 | Y185 | Sugiyama | ST13P5 FAM10A5 | NAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEAAHDL |
| Q8NI22 | Y135 | Sugiyama | MCFD2 SDNSF | DELINIIDGVLRDDDKNNDGyIDyAEFAKSLQ_________ |
| Q8NI22 | Y138 | Sugiyama | MCFD2 SDNSF | INIIDGVLRDDDKNNDGyIDyAEFAKSLQ____________ |
| Q8TD19 | Y52 | Sugiyama | NEK9 KIAA1995 NEK8 NERCC | PSASQGPRAGGGAAEQEELHyIPIRVLGRGAFGEAtLyRRT |
| Q8TDD1 | Y681 | Sugiyama | DDX54 | GPNRGAKRRREEARQRDQEFyIPyRPKDFDSERGLsIsGEG |
| Q8WYP5 | Y1790 | Sugiyama | AHCTF1 ELYS TMBS62 MSTP108 | QSVRKKTRKAKEISEASENIySDVRGLsQNQQIPQNsVtPR |
| Q92598 | Y641 | Sugiyama | HSPH1 HSP105 HSP110 KIAA0201 | MIMQDKLEKERNDAKNAVEEyVyEFRDKLCGPYEKFICEQD |
| Q92598 | Y643 | Sugiyama | HSPH1 HSP105 HSP110 KIAA0201 | MQDKLEKERNDAKNAVEEyVyEFRDKLCGPYEKFICEQDHQ |
| Q93079 | Y41 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q93079 | Y43 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q96CT7 | Y38 | Sugiyama | CCDC124 | RRAEAKAAADAKKQKELEDAyWKDDDKHVMRKEQRKEEKEK |
| Q96CW6 | Y300 | Sugiyama | SLC7A6OS | GSSRQRMWSKYPLDVQKEFGyDsPHDLDsD___________ |
| Q96EU6 | Y138 | Sugiyama | RRP36 C6orf153 HSPC253 | RDPRFDDLSGEYNPEVFDKtyQFLNDIRAKEKELVKKQLKK |
| Q96QK1 | Y507 | Sugiyama | VPS35 MEM3 TCCCTA00141 | EQSLVGRFIHLLRsEDPDQQyLILNTARKHFGAGGNQRIRF |
| Q99426 | Y98 | Sugiyama | TBCB CG22 CKAP1 | PVDDGCRIHVIDHsGARLGEyEDVSRVEKytIsQEAyDQRQ |
| Q99459 | Y511 | Sugiyama | CDC5L KIAA0432 PCDC5RP | EIVLPENAEKELEEREIDDtyIEDAADVDARKQAIRDAERV |
| Q99460 | Y950 | Sugiyama | PSMD1 | AHGPKIEEEEQEPEPPEPFEyIDD_________________ |
| Q99536 | Y245 | Sugiyama | VAT1 | KHEALKENGVTHPIDyHttDyVDEIKKISPKGVDIVMDPLG |
| Q99543 | Y137 | Sugiyama | DNAJC2 MPHOSPH11 MPP11 ZRF1 | KHHPDKRKAAGEPIKEGDNDyFTCITKAYEMLSDPVKRRAF |
| Q99543 | Y274 | Sugiyama | DNAJC2 MPHOSPH11 MPP11 ZRF1 | TRAQRKKEEMNRIRtLVDNAysCDPRIKKFKEEEKAKKEAE |
| Q99613 | Y148 | Sugiyama | EIF3C EIF3S8 | KKMNKNNAKALSTLRQKIRKyNRDFEsHItSyKQNPEQsAD |
| Q99613 | Y159 | Sugiyama | EIF3C EIF3S8 | STLRQKIRKyNRDFEsHItSyKQNPEQsADEDAEKNEEDsE |
| Q99614 | Y96 | Sugiyama | TTC1 TPR1 | ADKVENKsNEDVNssELDEEyLIELEKNMSDEEKQKRREES |
| Q99733 | Y95 | Sugiyama | NAP1L4 NAP2 | VRCAHIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVE |
| Q99733 | Y99 | Sugiyama | NAP1L4 NAP2 | HIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVEPtDA |
| Q99848 | Y265 | Sugiyama | EBNA1BP2 EBP2 | NQKFGFGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPG |
| Q99877 | Y41 | Sugiyama | H2BC15 H2BFD HIST1H2BN | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q99877 | Y43 | Sugiyama | H2BC15 H2BFD HIST1H2BN | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q99879 | Y41 | Sugiyama | H2BC14 H2BFE HIST1H2BM | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q99879 | Y43 | Sugiyama | H2BC14 H2BFE HIST1H2BM | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q99880 | Y41 | Sugiyama | H2BC13 H2BFC HIST1H2BL | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q99880 | Y43 | Sugiyama | H2BC13 H2BFC HIST1H2BL | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q9BQE3 | Y432 | Sugiyama | TUBA1C TUBA6 | GMEEGEFSEAREDMAALEKDyEEVGADsADGEDEGEEy___ |
| Q9BRK5 | Y162 | Sugiyama | SDF4 CAB45 PSEC0034 | sKTHFRAVDPDGDGHVsWDEyKVKFLASKGHSEKEVADAIR |
| Q9BRK5 | Y342 | Sugiyama | SDF4 CAB45 PSEC0034 | MIAVADENQNHHLEPEEVLKysEFFTGSKLVDYARsVHEEF |
| Q9BRL6 | Y44 | Sugiyama | SRSF8 SFRS2B SRP46 | RtsPDsLRRVFEKYGRVGDVyIPREPHTKAPRGFAFVRFHD |
| Q9BTD8 | Y424 | Sugiyama | RBM42 | FPsFLKAKVIRDKRTGKTKGyGFVSFKDPsDyVRAMREMNG |
| Q9BTD8 | Y435 | Sugiyama | RBM42 | DKRTGKTKGyGFVSFKDPsDyVRAMREMNGKYVGSRPIKLR |
| Q9BVA1 | T107 | Sugiyama | TUBB2B | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q9BXS5 | Y418 | Sugiyama | AP1M1 CLTNM | IEKSGYQALPWVRYITQNGDyQLRtQ_______________ |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9BYX7 | Y362 | Sugiyama | POTEKP ACTBL3 FKSG30 | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| Q9BZI7 | Y117 | Sugiyama | UPF3B RENT3B UPF3X | AYINFKNQEDIILFRDRFDGyVFLDNKGQEYPAIVEFAPFQ |
| Q9BZI7 | Y167 | Sugiyama | UPF3B RENT3B UPF3X | RDTKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIEA |
| Q9GZT8 | Y175 | Sugiyama | NIF3L1 ALS2CR1 MDS015 My018 | PSKAPNyPTEGNHRVEFNVNytQDLDKVMSAVKGIDGVsVT |
| Q9H1E3 | Y146 | Sugiyama | NUCKS1 NUCKS JC7 | QEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPERKE |
| Q9H6F5 | Y109 | Sugiyama | CCDC86 CYCLON | AAsPQRQQDLHLEsPQRQPEysPEsPRCQPKPSEEAPKCsQ |
| Q9H814 | Y309 | Sugiyama | PHAX RNUXA | FLNLLKNtPsISEEQIKDIFyIENQKEYENKKAARKRRTQV |
| Q9H814 | Y57 | Sugiyama | PHAX RNUXA | GDsAMRAFQNTAtACAPVSHyRAVESVDSSEESFSDSDDDS |
| Q9HCN8 | Y81 | Sugiyama | SDF2L1 UNQ1941/PRO4424 | GSGSGQQSVtGVEAsDDANSyWRIRGGSEGGCPRGSPVRCG |
| Q9HDC5 | Y417 | Sugiyama | JPH1 JP1 | AARQECDIARAVARELsPDFyQPGPDyVKQRFQEGVDAKEN |
| Q9HDC5 | Y423 | Sugiyama | JPH1 JP1 | DIARAVARELsPDFyQPGPDyVKQRFQEGVDAKENPEEKVP |
| Q9NPI1 | Y190 | Sugiyama | BRD7 BP75 CELTIX1 | MIIKHPMDFSTMKEKIKNNDyQsIEELKDNFKLMCTNAMIY |
| Q9NRX4 | Y116 | Sugiyama | PHPT1 PHP14 CGI-202 HSPC141 | AyGPAQHAISTEKIKAKyPDyEVtWANDGy___________ |
| Q9NUL3 | Y326 | Sugiyama | STAU2 | MNPISRLAQIQQAKKEKEPDyVLLSERGMPRRREFVMQVKV |
| Q9NVS9 | Y157 | Sugiyama | PNPO | NRQVRVEGPVKKLPEEEAECyFHSRPKssQIGAVVSHQSSV |
| Q9NY12 | Y145 | Sugiyama | GAR1 NOLA1 | FSVKLSENMKASSFKKLQKFyIDPyKLLPLQRFLPRPPGEK |
| Q9NY12 | Y149 | Sugiyama | GAR1 NOLA1 | LSENMKASSFKKLQKFyIDPyKLLPLQRFLPRPPGEKGPPR |
| Q9NYF8 | Y408 | Sugiyama | BCLAF1 BTF KIAA0164 | EsGKQKFNDsEGDDtEEtEDyRQFRKsVLADQGKsFATAsH |
| Q9NYU2 | Y966 | Sugiyama | UGGT1 GT UGCGL1 UGGT UGT1 UGTR | LVMKVDALLsAQPKGDPRIEyQFFEDRHSAIKLRPKEGETY |
| Q9NZB2 | Y418 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | SEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERssPIN |
| Q9NZB2 | Y9 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | ____________MGVQGFQDyIEKHCPsAVVPVELQKLARG |
| Q9P031 | Y97 | Sugiyama | CCDC59 BR22 TAP26 HSPC128 | AQTSLESQFtDRYPDNLKHLyLAEEERHRKQARKVDHPLSE |
| Q9UBR2 | Y76 | Sugiyama | CTSZ | YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA |
| Q9UI15 | Y192 | Sugiyama | TAGLN3 NP25 | NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________ |
| Q9UIQ6 | Y70 | Sugiyama | LNPEP OTASE | GsRLLVRGLGEHEMEEDEEDyEssAKLLGMsFMNRssGLRN |
| Q9UJU6 | Y16 | Sugiyama | DBNL CMAP SH3P7 PP5423 | _____MAANLSRNGPALQEAyVRVVtEKsPtDWALFTyEGN |
| Q9UK59 | Y533 | Sugiyama | DBR1 | LsDEHEPEQRKKIKRRNQAIyAAVDDDDDDAA_________ |
| Q9UMS0 | Y194 | Sugiyama | NFU1 HIRIP5 CGI-33 | KELLDTRIRPTVQEDGGDVIyKGFEDGIVQLKLQGSCTSCP |
| Q9UMX5 | Y65 | Sugiyama | NENF CIR2 SPUF | RLFtEEELARYGGEEEDQPIyLAVKGVVFDVtSGKEFYGRG |
| Q9UNH7 | Y220 | Sugiyama | SNX6 | VSGVKDVDDFFEHERTFLLEyHNRVKDASAKSDRMTRSHKS |
| Q9UNZ2 | Y167 | Sugiyama | NSFL1C UBXN2C | PRPFAGGGYRLGAAPEEEsAyVAGEKRQHssQDVHVVLKLW |
| Q9UQ80 | Y98 | Sugiyama | PA2G4 EBP1 | TSISVNNCVCHFsPLKSDQDyILKEGDLVKIDLGVHVDGFI |
| Q9Y230 | Y446 | Sugiyama | RUVBL2 INO80J TIP48 TIP49B CGI-46 | IKRVysLFLDEsRSTQYMKEyQDAFLFNELKGEtMDTS___ |
| Q9Y2B0 | Y71 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | IQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEICDRMKE |
| Q9Y2T7 | Y107 | Sugiyama | YBX2 CSDA3 MSY2 | KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK |
| Q9Y3U8 | Y53 | Sugiyama | RPL36 | LTKHTKFVRDMIREVCGFAPyERRAMELLKVSKDKRALKFI |
| Q9Y450 | Y58 | Sugiyama | HBS1L HBS1 KIAA1038 | AQFIYSRRDKPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQ |
| Q9Y5Q8 | Y393 | Sugiyama | GTF3C5 CDABP0017 | SGtsGARKPASSKYKLKDSVyIFREGALPPYRQMFYQLCDL |
| Q9Y5S9 | S56 | Sugiyama | RBM8A RBM8 HSPC114 MDS014 | KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF |
| Q9Y639 | Y216 | Sugiyama | NPTN SDFR1 SDR1 | KNASNMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKA |
| Q9Y639 | Y220 | Sugiyama | NPTN SDFR1 SDR1 | NMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKAAPDI |
| Q9Y696 | Y244 | Sugiyama | CLIC4 | AysRDEFtNtCPsDKEVEIAysDVAKRLTK___________ |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 2.486900e-14 | 13.604 | 1 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.574241e-11 | 10.803 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 5.609874e-09 | 8.251 | 1 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 7.799251e-09 | 8.108 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 2.971059e-08 | 7.527 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 3.417333e-08 | 7.466 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 7.314790e-08 | 7.136 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 2.682554e-07 | 6.571 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 4.781465e-07 | 6.320 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 4.663056e-07 | 6.331 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 8.338781e-07 | 6.079 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 7.904389e-07 | 6.102 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 1.836166e-06 | 5.736 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 3.497625e-06 | 5.456 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 6.375136e-06 | 5.196 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 6.732776e-06 | 5.172 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 1.259049e-05 | 4.900 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.161382e-05 | 4.935 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 1.225330e-05 | 4.912 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 1.374679e-05 | 4.862 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.820547e-05 | 4.740 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 2.740162e-05 | 4.562 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 2.740162e-05 | 4.562 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 3.097537e-05 | 4.509 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 3.463943e-05 | 4.460 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 3.834589e-05 | 4.416 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 5.584290e-05 | 4.253 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 5.956242e-05 | 4.225 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 6.353725e-05 | 4.197 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 9.321848e-05 | 4.030 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 9.891830e-05 | 4.005 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 9.936233e-05 | 4.003 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.357612e-04 | 3.867 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 1.499154e-04 | 3.824 | 0 | 0 |
| Activation of TRKA receptors | R-HSA-187015 | 1.721729e-04 | 3.764 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 2.020032e-04 | 3.695 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 2.032711e-04 | 3.692 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 2.069525e-04 | 3.684 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 2.147565e-04 | 3.668 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 3.023990e-04 | 3.519 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 2.930002e-04 | 3.533 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.831006e-04 | 3.548 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 3.696888e-04 | 3.432 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 3.696888e-04 | 3.432 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 3.574218e-04 | 3.447 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 3.696888e-04 | 3.432 | 0 | 0 |
| Disease | R-HSA-1643685 | 3.623937e-04 | 3.441 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 3.851978e-04 | 3.414 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 4.582200e-04 | 3.339 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 4.912187e-04 | 3.309 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 5.380805e-04 | 3.269 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 5.593053e-04 | 3.252 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 5.974262e-04 | 3.224 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 6.736307e-04 | 3.172 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 6.986581e-04 | 3.156 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 8.421374e-04 | 3.075 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 7.977430e-04 | 3.098 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 8.018574e-04 | 3.096 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 8.301583e-04 | 3.081 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 7.977430e-04 | 3.098 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 8.814745e-04 | 3.055 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 9.654340e-04 | 3.015 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 9.701570e-04 | 3.013 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 1.102536e-03 | 2.958 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 1.079708e-03 | 2.967 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 1.102536e-03 | 2.958 | 0 | 0 |
| TRKA activation by NGF | R-HSA-187042 | 1.306861e-03 | 2.884 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.301705e-03 | 2.885 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.254767e-03 | 2.901 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 1.457831e-03 | 2.836 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.457831e-03 | 2.836 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 1.466149e-03 | 2.834 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.540870e-03 | 2.812 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.679583e-03 | 2.775 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.679583e-03 | 2.775 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.986374e-03 | 2.702 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.986374e-03 | 2.702 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 2.009185e-03 | 2.697 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 2.105719e-03 | 2.677 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 2.067921e-03 | 2.684 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 2.016865e-03 | 2.695 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 2.132936e-03 | 2.671 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 2.222895e-03 | 2.653 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 2.225461e-03 | 2.653 | 0 | 0 |
| IRS activation | R-HSA-74713 | 2.526651e-03 | 2.597 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 2.526651e-03 | 2.597 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 2.452712e-03 | 2.610 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 2.448140e-03 | 2.611 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 2.337601e-03 | 2.631 | 0 | 0 |
| NGF-independant TRKA activation | R-HSA-187024 | 3.277652e-03 | 2.484 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 2.977244e-03 | 2.526 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 2.977244e-03 | 2.526 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 2.963437e-03 | 2.528 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 2.978839e-03 | 2.526 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 3.102267e-03 | 2.508 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 2.977244e-03 | 2.526 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 3.047300e-03 | 2.516 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 3.295365e-03 | 2.482 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 3.295365e-03 | 2.482 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 3.633551e-03 | 2.440 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 3.633551e-03 | 2.440 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 4.120064e-03 | 2.385 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 4.029405e-03 | 2.395 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 3.825107e-03 | 2.417 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 4.286167e-03 | 2.368 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 4.286167e-03 | 2.368 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 3.992184e-03 | 2.399 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 4.208665e-03 | 2.376 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 4.371626e-03 | 2.359 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 4.371626e-03 | 2.359 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 4.548003e-03 | 2.342 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 4.766850e-03 | 2.322 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 5.051932e-03 | 2.297 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 5.194299e-03 | 2.284 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 5.194299e-03 | 2.284 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 5.194299e-03 | 2.284 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 6.104120e-03 | 2.214 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 6.104120e-03 | 2.214 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.071331e-03 | 2.217 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 5.884150e-03 | 2.230 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 5.692959e-03 | 2.245 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 5.514642e-03 | 2.258 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 5.870255e-03 | 2.231 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 6.188445e-03 | 2.208 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 6.503028e-03 | 2.187 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 6.718487e-03 | 2.173 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 6.738687e-03 | 2.171 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 6.828045e-03 | 2.166 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 6.828045e-03 | 2.166 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 6.966251e-03 | 2.157 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 7.052963e-03 | 2.152 | 0 | 0 |
| Drug resistance of FLT3 mutants | R-HSA-9702506 | 1.037893e-02 | 1.984 | 0 | 0 |
| Drug resistance of KIT mutants | R-HSA-9669937 | 1.037893e-02 | 1.984 | 0 | 0 |
| Drug resistance of PDGFR mutants | R-HSA-9674415 | 1.037893e-02 | 1.984 | 0 | 0 |
| KIT mutants bind TKIs | R-HSA-9669921 | 1.037893e-02 | 1.984 | 0 | 0 |
| FLT3 mutants bind TKIs | R-HSA-9702509 | 1.037893e-02 | 1.984 | 0 | 0 |
| PDGFR mutants bind TKIs | R-HSA-9674428 | 1.037893e-02 | 1.984 | 0 | 0 |
| Sunitinib-resistant KIT mutants | R-HSA-9669934 | 1.037893e-02 | 1.984 | 0 | 0 |
| midostaurin-resistant FLT3 mutants | R-HSA-9702600 | 1.037893e-02 | 1.984 | 0 | 0 |
| quizartinib-resistant FLT3 mutants | R-HSA-9702620 | 1.037893e-02 | 1.984 | 0 | 0 |
| tamatinib-resistant FLT3 mutants | R-HSA-9703009 | 1.037893e-02 | 1.984 | 0 | 0 |
| Dasatinib-resistant KIT mutants | R-HSA-9669914 | 1.037893e-02 | 1.984 | 0 | 0 |
| gilteritinib-resistant FLT3 mutants | R-HSA-9702590 | 1.037893e-02 | 1.984 | 0 | 0 |
| KW2449-resistant FLT3 mutants | R-HSA-9702569 | 1.037893e-02 | 1.984 | 0 | 0 |
| semaxanib-resistant FLT3 mutants | R-HSA-9702577 | 1.037893e-02 | 1.984 | 0 | 0 |
| sorafenib-resistant FLT3 mutants | R-HSA-9702624 | 1.037893e-02 | 1.984 | 0 | 0 |
| Imatinib-resistant PDGFR mutants | R-HSA-9674396 | 1.037893e-02 | 1.984 | 0 | 0 |
| crenolanib-resistant FLT3 mutants | R-HSA-9702581 | 1.037893e-02 | 1.984 | 0 | 0 |
| tandutinib-resistant FLT3 mutants | R-HSA-9702636 | 1.037893e-02 | 1.984 | 0 | 0 |
| Sorafenib-resistant PDGFR mutants | R-HSA-9674404 | 1.037893e-02 | 1.984 | 0 | 0 |
| Masitinib-resistant KIT mutants | R-HSA-9669924 | 1.037893e-02 | 1.984 | 0 | 0 |
| linifanib-resistant FLT3 mutants | R-HSA-9702998 | 1.037893e-02 | 1.984 | 0 | 0 |
| Sunitinib-resistant PDGFR mutants | R-HSA-9674401 | 1.037893e-02 | 1.984 | 0 | 0 |
| Regorafenib-resistant PDGFR mutants | R-HSA-9674403 | 1.037893e-02 | 1.984 | 0 | 0 |
| Regorafenib-resistant KIT mutants | R-HSA-9669929 | 1.037893e-02 | 1.984 | 0 | 0 |
| Imatinib-resistant KIT mutants | R-HSA-9669917 | 1.037893e-02 | 1.984 | 0 | 0 |
| sunitinib-resistant FLT3 mutants | R-HSA-9702632 | 1.037893e-02 | 1.984 | 0 | 0 |
| ponatinib-resistant FLT3 mutants | R-HSA-9702614 | 1.037893e-02 | 1.984 | 0 | 0 |
| lestaurtinib-resistant FLT3 mutants | R-HSA-9702596 | 1.037893e-02 | 1.984 | 0 | 0 |
| Nilotinib-resistant KIT mutants | R-HSA-9669926 | 1.037893e-02 | 1.984 | 0 | 0 |
| pexidartinib-resistant FLT3 mutants | R-HSA-9702605 | 1.037893e-02 | 1.984 | 0 | 0 |
| Sorafenib-resistant KIT mutants | R-HSA-9669936 | 1.037893e-02 | 1.984 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 8.365169e-03 | 2.078 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 1.098677e-02 | 1.959 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.098677e-02 | 1.959 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 1.241597e-02 | 1.906 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 1.241597e-02 | 1.906 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.241597e-02 | 1.906 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.241597e-02 | 1.906 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.241597e-02 | 1.906 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.241597e-02 | 1.906 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.241597e-02 | 1.906 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 9.378039e-03 | 2.028 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 1.065679e-02 | 1.972 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 1.065679e-02 | 1.972 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 1.241597e-02 | 1.906 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.065679e-02 | 1.972 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 8.365169e-03 | 2.078 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 8.365169e-03 | 2.078 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 7.163638e-03 | 2.145 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 9.378039e-03 | 2.028 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 7.747808e-03 | 2.111 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 7.747808e-03 | 2.111 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 9.635906e-03 | 2.016 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 9.378039e-03 | 2.028 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.024548e-02 | 1.989 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 1.133214e-02 | 1.946 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 1.000548e-02 | 2.000 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.184371e-02 | 1.927 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 1.241597e-02 | 1.906 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 7.867115e-03 | 2.104 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 1.241597e-02 | 1.906 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 1.241597e-02 | 1.906 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 1.241597e-02 | 1.906 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 7.773790e-03 | 2.109 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 1.133214e-02 | 1.946 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.137298e-02 | 1.944 | 0 | 0 |
| Depurination | R-HSA-73927 | 1.203167e-02 | 1.920 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 7.637179e-03 | 2.117 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 8.194084e-03 | 2.086 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 9.635906e-03 | 2.016 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 8.194084e-03 | 2.086 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.170654e-02 | 1.932 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 8.795615e-03 | 2.056 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.144195e-02 | 1.942 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.112501e-02 | 1.954 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 9.794907e-03 | 2.009 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.203199e-02 | 1.920 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 9.378039e-03 | 2.028 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.270306e-02 | 1.896 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 1.350380e-02 | 1.870 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 1.350380e-02 | 1.870 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.374923e-02 | 1.862 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 1.407829e-02 | 1.851 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 1.407829e-02 | 1.851 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 1.427663e-02 | 1.845 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 1.427663e-02 | 1.845 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.550244e-02 | 1.810 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 1.550244e-02 | 1.810 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.589632e-02 | 1.799 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.589632e-02 | 1.799 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.629610e-02 | 1.788 | 1 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 1.674333e-02 | 1.776 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 1.674333e-02 | 1.776 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 1.674333e-02 | 1.776 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.065076e-02 | 1.685 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 1.715628e-02 | 1.766 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.715628e-02 | 1.766 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 1.888163e-02 | 1.724 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.715628e-02 | 1.766 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 1.715628e-02 | 1.766 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 1.943377e-02 | 1.711 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.888163e-02 | 1.724 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 1.851201e-02 | 1.733 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 1.851201e-02 | 1.733 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 1.999656e-02 | 1.699 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 1.715628e-02 | 1.766 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.067683e-02 | 1.685 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 2.254027e-02 | 1.647 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 2.254027e-02 | 1.647 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 1.913953e-02 | 1.718 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 2.135231e-02 | 1.671 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.135202e-02 | 1.671 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.254027e-02 | 1.647 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 2.135231e-02 | 1.671 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 1.761521e-02 | 1.754 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 2.234912e-02 | 1.651 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 2.005251e-02 | 1.698 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 2.275066e-02 | 1.643 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 2.275066e-02 | 1.643 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 2.441784e-02 | 1.612 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 2.447036e-02 | 1.611 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 2.447036e-02 | 1.611 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.447036e-02 | 1.611 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 2.548973e-02 | 1.594 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 2.646553e-02 | 1.577 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 2.727608e-02 | 1.564 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 2.770846e-02 | 1.557 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 2.852424e-02 | 1.545 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 3.064497e-02 | 1.514 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 3.064497e-02 | 1.514 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 3.064497e-02 | 1.514 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 3.064497e-02 | 1.514 | 0 | 0 |
| NTRK3 as a dependence receptor | R-HSA-9603505 | 3.081661e-02 | 1.511 | 0 | 0 |
| Signaling by extracellular domain mutants of KIT | R-HSA-9680187 | 3.081661e-02 | 1.511 | 0 | 0 |
| Signaling by juxtamembrane domain KIT mutants | R-HSA-9669935 | 3.081661e-02 | 1.511 | 0 | 0 |
| Signaling by kinase domain mutants of KIT | R-HSA-9669933 | 3.081661e-02 | 1.511 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 3.081661e-02 | 1.511 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 3.153954e-02 | 1.501 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 3.282624e-02 | 1.484 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 3.282624e-02 | 1.484 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 3.282624e-02 | 1.484 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 3.319045e-02 | 1.479 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 3.369047e-02 | 1.472 | 0 | 0 |
| NTF3 activates NTRK2 (TRKB) signaling | R-HSA-9025046 | 4.087756e-02 | 1.389 | 0 | 0 |
| BDNF activates NTRK2 (TRKB) signaling | R-HSA-9024909 | 4.087756e-02 | 1.389 | 0 | 0 |
| NTF4 activates NTRK2 (TRKB) signaling | R-HSA-9026357 | 4.087756e-02 | 1.389 | 0 | 0 |
| NTF3 activates NTRK3 signaling | R-HSA-9034013 | 4.087756e-02 | 1.389 | 0 | 0 |
| Activated NTRK3 signals through PLCG1 | R-HSA-9034793 | 5.083468e-02 | 1.294 | 0 | 0 |
| PLC-gamma1 signalling | R-HSA-167021 | 5.083468e-02 | 1.294 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 5.083468e-02 | 1.294 | 0 | 0 |
| Signalling to STAT3 | R-HSA-198745 | 5.083468e-02 | 1.294 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 5.083468e-02 | 1.294 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 3.506656e-02 | 1.455 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 3.506656e-02 | 1.455 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 3.506656e-02 | 1.455 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 3.971863e-02 | 1.401 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 4.458991e-02 | 1.351 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 4.710433e-02 | 1.327 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 4.710433e-02 | 1.327 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 4.458991e-02 | 1.351 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 3.506656e-02 | 1.455 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 4.966948e-02 | 1.304 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 3.736450e-02 | 1.428 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 4.899846e-02 | 1.310 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 4.453599e-02 | 1.351 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 4.458991e-02 | 1.351 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 4.087756e-02 | 1.389 | 1 | 1 |
| MET activates STAT3 | R-HSA-8875791 | 5.083468e-02 | 1.294 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 5.083468e-02 | 1.294 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 3.971863e-02 | 1.401 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 3.912304e-02 | 1.408 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 3.783899e-02 | 1.422 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 4.212756e-02 | 1.375 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 4.599989e-02 | 1.337 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 5.035016e-02 | 1.298 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 5.083468e-02 | 1.294 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 4.458991e-02 | 1.351 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 4.710433e-02 | 1.327 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 3.937592e-02 | 1.405 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 3.496099e-02 | 1.456 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 4.388659e-02 | 1.358 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 3.891937e-02 | 1.410 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 5.053287e-02 | 1.296 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 4.453599e-02 | 1.351 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 4.675329e-02 | 1.330 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 3.409178e-02 | 1.467 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 4.284307e-02 | 1.368 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 3.590091e-02 | 1.445 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 3.593697e-02 | 1.444 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 3.757553e-02 | 1.425 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 3.757553e-02 | 1.425 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 3.496099e-02 | 1.456 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 3.496099e-02 | 1.456 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 3.496099e-02 | 1.456 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 3.496099e-02 | 1.456 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 3.496099e-02 | 1.456 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 5.092182e-02 | 1.293 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 5.209050e-02 | 1.283 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 5.228405e-02 | 1.282 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 5.228405e-02 | 1.282 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 5.228405e-02 | 1.282 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 5.373513e-02 | 1.270 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 5.494676e-02 | 1.260 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 5.494676e-02 | 1.260 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 5.527481e-02 | 1.257 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 5.527481e-02 | 1.257 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 5.630181e-02 | 1.249 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 5.765633e-02 | 1.239 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 5.765633e-02 | 1.239 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.855015e-02 | 1.232 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 5.855015e-02 | 1.232 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 5.998365e-02 | 1.222 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 5.998365e-02 | 1.222 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 5.998365e-02 | 1.222 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 6.041153e-02 | 1.219 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 6.068904e-02 | 1.217 | 0 | 0 |
| Activated NTRK2 signals through PLCG1 | R-HSA-9026527 | 6.068904e-02 | 1.217 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 6.068904e-02 | 1.217 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 6.068904e-02 | 1.217 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 6.068904e-02 | 1.217 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 6.068904e-02 | 1.217 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 6.068904e-02 | 1.217 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 6.252086e-02 | 1.204 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 6.321112e-02 | 1.199 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 6.321112e-02 | 1.199 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 6.321112e-02 | 1.199 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 6.321112e-02 | 1.199 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 6.605390e-02 | 1.180 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 6.712793e-02 | 1.173 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 6.712793e-02 | 1.173 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 6.890883e-02 | 1.162 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 6.893869e-02 | 1.162 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 6.893869e-02 | 1.162 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 6.893869e-02 | 1.162 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 6.938421e-02 | 1.159 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 7.044170e-02 | 1.152 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 7.044170e-02 | 1.152 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 7.044170e-02 | 1.152 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 7.044170e-02 | 1.152 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 7.044170e-02 | 1.152 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 7.055686e-02 | 1.151 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 7.186431e-02 | 1.143 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 7.186431e-02 | 1.143 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 7.186431e-02 | 1.143 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 8.009369e-02 | 1.096 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 8.009369e-02 | 1.096 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 8.009369e-02 | 1.096 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 8.009369e-02 | 1.096 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 8.964605e-02 | 1.047 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 8.964605e-02 | 1.047 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 9.909980e-02 | 1.004 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 9.909980e-02 | 1.004 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 9.909980e-02 | 1.004 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 9.909980e-02 | 1.004 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 9.909980e-02 | 1.004 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 9.909980e-02 | 1.004 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 9.909980e-02 | 1.004 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 9.909980e-02 | 1.004 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 9.909980e-02 | 1.004 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 1.084560e-01 | 0.965 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 1.084560e-01 | 0.965 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 1.084560e-01 | 0.965 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 1.084560e-01 | 0.965 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 1.084560e-01 | 0.965 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 1.084560e-01 | 0.965 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 1.084560e-01 | 0.965 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 1.177155e-01 | 0.929 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 1.177155e-01 | 0.929 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 1.177155e-01 | 0.929 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.268795e-01 | 0.897 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.359488e-01 | 0.867 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.359488e-01 | 0.867 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.359488e-01 | 0.867 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.359488e-01 | 0.867 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 8.087484e-02 | 1.092 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 8.706553e-02 | 1.060 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.097584e-01 | 0.960 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.302904e-01 | 0.885 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.302904e-01 | 0.885 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 1.337946e-01 | 0.874 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.373201e-01 | 0.862 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.444317e-01 | 0.840 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 1.408034e-01 | 0.851 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 1.408034e-01 | 0.851 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 9.021277e-02 | 1.045 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 9.909980e-02 | 1.004 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 9.339320e-02 | 1.030 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.268795e-01 | 0.897 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 8.706553e-02 | 1.060 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 7.783351e-02 | 1.109 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 1.131173e-01 | 0.946 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.188877e-02 | 1.037 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 1.084560e-01 | 0.965 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 8.706553e-02 | 1.060 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 8.964605e-02 | 1.047 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 9.909980e-02 | 1.004 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 1.084560e-01 | 0.965 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 1.268795e-01 | 0.897 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 1.268795e-01 | 0.897 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.359488e-01 | 0.867 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 1.449245e-01 | 0.839 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.449245e-01 | 0.839 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 1.449245e-01 | 0.839 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.444317e-01 | 0.840 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 1.067782e-01 | 0.972 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 1.091877e-01 | 0.962 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 1.031236e-01 | 0.987 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 8.003589e-02 | 1.097 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.064269e-01 | 0.973 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 9.909980e-02 | 1.004 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 1.177155e-01 | 0.929 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 8.395254e-02 | 1.076 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.051185e-01 | 0.978 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 8.706553e-02 | 1.060 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 8.706553e-02 | 1.060 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 8.009369e-02 | 1.096 | 1 | 1 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 1.449245e-01 | 0.839 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 1.031236e-01 | 0.987 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 9.339320e-02 | 1.030 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.097584e-01 | 0.960 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.097584e-01 | 0.960 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.097584e-01 | 0.960 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 8.009369e-02 | 1.096 | 1 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 1.084560e-01 | 0.965 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 1.177155e-01 | 0.929 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 1.268795e-01 | 0.897 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 1.359488e-01 | 0.867 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.101330e-01 | 0.958 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 9.339320e-02 | 1.030 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.097584e-01 | 0.960 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 8.009369e-02 | 1.096 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 8.009369e-02 | 1.096 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 9.909980e-02 | 1.004 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 1.359488e-01 | 0.867 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 1.087427e-01 | 0.964 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 1.031236e-01 | 0.987 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 1.031236e-01 | 0.987 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 9.660582e-02 | 1.015 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 1.233489e-01 | 0.909 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.420123e-01 | 0.848 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 8.062252e-02 | 1.094 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 1.044220e-01 | 0.981 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 9.660582e-02 | 1.015 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.153517e-01 | 0.938 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 8.767165e-02 | 1.057 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 9.393166e-02 | 1.027 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.271717e-01 | 0.896 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 1.423513e-01 | 0.847 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 1.336823e-01 | 0.874 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 9.339320e-02 | 1.030 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 8.587438e-02 | 1.066 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 1.153517e-01 | 0.938 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 1.302904e-01 | 0.885 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 8.196216e-02 | 1.086 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.290075e-01 | 0.889 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 1.087427e-01 | 0.964 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.067782e-01 | 0.972 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.456208e-01 | 0.837 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 1.480161e-01 | 0.830 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.516187e-01 | 0.819 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 1.538075e-01 | 0.813 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.538075e-01 | 0.813 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.538075e-01 | 0.813 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 1.538075e-01 | 0.813 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 1.538075e-01 | 0.813 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.538075e-01 | 0.813 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 1.538075e-01 | 0.813 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 1.538075e-01 | 0.813 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 1.552385e-01 | 0.809 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 1.552385e-01 | 0.809 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 1.552385e-01 | 0.809 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 1.578950e-01 | 0.802 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 1.588750e-01 | 0.799 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.603877e-01 | 0.795 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.616601e-01 | 0.791 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.620593e-01 | 0.790 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 1.625274e-01 | 0.789 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 1.625274e-01 | 0.789 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 1.625988e-01 | 0.789 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 1.625988e-01 | 0.789 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 1.625988e-01 | 0.789 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.625988e-01 | 0.789 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.625988e-01 | 0.789 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 1.661948e-01 | 0.779 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.679368e-01 | 0.775 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 1.712992e-01 | 0.766 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 1.712992e-01 | 0.766 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 1.712992e-01 | 0.766 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 1.712992e-01 | 0.766 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 1.712992e-01 | 0.766 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.712992e-01 | 0.766 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.772813e-01 | 0.751 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 1.799098e-01 | 0.745 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 1.799098e-01 | 0.745 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 1.799098e-01 | 0.745 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 1.799098e-01 | 0.745 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 1.799098e-01 | 0.745 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 1.799098e-01 | 0.745 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.799098e-01 | 0.745 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.859384e-01 | 0.731 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.881574e-01 | 0.725 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 1.884315e-01 | 0.725 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.884315e-01 | 0.725 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 1.884315e-01 | 0.725 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 1.884315e-01 | 0.725 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 1.884315e-01 | 0.725 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 1.884315e-01 | 0.725 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 1.884315e-01 | 0.725 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 1.884315e-01 | 0.725 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 1.884315e-01 | 0.725 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 1.884315e-01 | 0.725 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 1.884796e-01 | 0.725 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 1.898273e-01 | 0.722 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.959987e-01 | 0.708 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 1.959987e-01 | 0.708 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.968651e-01 | 0.706 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 1.968651e-01 | 0.706 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 1.968651e-01 | 0.706 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 1.968651e-01 | 0.706 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 1.990943e-01 | 0.701 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 2.052116e-01 | 0.688 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 2.052116e-01 | 0.688 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 2.052116e-01 | 0.688 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 2.052116e-01 | 0.688 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 2.073455e-01 | 0.683 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 2.111436e-01 | 0.675 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 2.111436e-01 | 0.675 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 2.134719e-01 | 0.671 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 2.134719e-01 | 0.671 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.134719e-01 | 0.671 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 2.134719e-01 | 0.671 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 2.134719e-01 | 0.671 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 2.134719e-01 | 0.671 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 2.134719e-01 | 0.671 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 2.149487e-01 | 0.668 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 2.149487e-01 | 0.668 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 2.151650e-01 | 0.667 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 2.216468e-01 | 0.654 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 2.216468e-01 | 0.654 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 2.216468e-01 | 0.654 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 2.216468e-01 | 0.654 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 2.216468e-01 | 0.654 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 2.216468e-01 | 0.654 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 2.216468e-01 | 0.654 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 2.216468e-01 | 0.654 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 2.216468e-01 | 0.654 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 2.216468e-01 | 0.654 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 2.233027e-01 | 0.651 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 2.264003e-01 | 0.645 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 2.287619e-01 | 0.641 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 2.297373e-01 | 0.639 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 2.297373e-01 | 0.639 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 2.297373e-01 | 0.639 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 2.297373e-01 | 0.639 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.297373e-01 | 0.639 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 2.297373e-01 | 0.639 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 2.340598e-01 | 0.631 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 2.340598e-01 | 0.631 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 2.369975e-01 | 0.625 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 2.377442e-01 | 0.624 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 2.377442e-01 | 0.624 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 2.377442e-01 | 0.624 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 2.377442e-01 | 0.624 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 2.417345e-01 | 0.617 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 2.452846e-01 | 0.610 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 2.456683e-01 | 0.610 | 0 | 0 |
| M Phase | R-HSA-68886 | 2.459137e-01 | 0.609 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 2.460360e-01 | 0.609 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 2.494208e-01 | 0.603 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 2.532670e-01 | 0.596 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 2.535105e-01 | 0.596 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.535105e-01 | 0.596 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 2.535105e-01 | 0.596 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 2.535105e-01 | 0.596 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 2.609635e-01 | 0.583 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 2.612717e-01 | 0.583 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 2.612717e-01 | 0.583 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 2.612717e-01 | 0.583 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 2.612717e-01 | 0.583 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 2.647906e-01 | 0.577 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.653852e-01 | 0.576 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 2.686624e-01 | 0.571 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 2.689527e-01 | 0.570 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.689527e-01 | 0.570 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 2.689527e-01 | 0.570 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 2.689527e-01 | 0.570 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 2.763604e-01 | 0.559 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 2.763604e-01 | 0.559 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 2.765542e-01 | 0.558 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 2.765542e-01 | 0.558 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 2.765542e-01 | 0.558 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 2.765542e-01 | 0.558 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 2.802080e-01 | 0.553 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.840542e-01 | 0.547 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 2.840542e-01 | 0.547 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 2.840772e-01 | 0.547 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 2.840772e-01 | 0.547 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 2.840772e-01 | 0.547 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 2.844807e-01 | 0.546 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.915225e-01 | 0.535 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.915225e-01 | 0.535 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 2.915225e-01 | 0.535 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 2.915225e-01 | 0.535 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 2.915225e-01 | 0.535 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 2.915225e-01 | 0.535 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 2.988907e-01 | 0.524 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 2.988907e-01 | 0.524 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.988907e-01 | 0.524 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.988907e-01 | 0.524 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 2.988907e-01 | 0.524 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 2.988907e-01 | 0.524 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 3.061828e-01 | 0.514 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 3.061828e-01 | 0.514 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 3.061828e-01 | 0.514 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 3.061828e-01 | 0.514 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 3.061828e-01 | 0.514 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.109061e-01 | 0.507 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 3.114653e-01 | 0.507 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 3.133995e-01 | 0.504 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 3.133995e-01 | 0.504 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 3.133995e-01 | 0.504 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 3.133995e-01 | 0.504 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 3.133995e-01 | 0.504 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 3.133995e-01 | 0.504 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 3.147277e-01 | 0.502 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 3.147277e-01 | 0.502 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 3.147277e-01 | 0.502 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 3.184846e-01 | 0.497 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 3.185447e-01 | 0.497 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 3.205415e-01 | 0.494 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 3.205415e-01 | 0.494 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 3.205415e-01 | 0.494 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.276097e-01 | 0.485 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 3.276097e-01 | 0.485 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 3.298476e-01 | 0.482 | 0 | 0 |
| Translation | R-HSA-72766 | 3.298844e-01 | 0.482 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 3.302494e-01 | 0.481 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 3.346049e-01 | 0.475 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 3.346049e-01 | 0.475 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 3.346049e-01 | 0.475 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 3.346049e-01 | 0.475 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 3.346049e-01 | 0.475 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 3.346049e-01 | 0.475 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 3.346049e-01 | 0.475 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 3.375498e-01 | 0.472 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 3.415276e-01 | 0.467 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 3.415276e-01 | 0.467 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.415276e-01 | 0.467 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 3.415276e-01 | 0.467 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 3.415276e-01 | 0.467 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 3.420253e-01 | 0.466 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 3.440463e-01 | 0.463 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 3.451092e-01 | 0.462 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 3.483788e-01 | 0.458 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 3.483788e-01 | 0.458 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 3.483788e-01 | 0.458 | 0 | 0 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | R-HSA-193775 | 3.551591e-01 | 0.450 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 3.563956e-01 | 0.448 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 3.563956e-01 | 0.448 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 3.563956e-01 | 0.448 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 3.601427e-01 | 0.444 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 3.610528e-01 | 0.442 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 3.618693e-01 | 0.441 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 3.618693e-01 | 0.441 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 3.618693e-01 | 0.441 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 3.618693e-01 | 0.441 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 3.618693e-01 | 0.441 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 3.618693e-01 | 0.441 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 3.638818e-01 | 0.439 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 3.638818e-01 | 0.439 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 3.641310e-01 | 0.439 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 3.667091e-01 | 0.436 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 3.685100e-01 | 0.434 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 3.685100e-01 | 0.434 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 3.685100e-01 | 0.434 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 3.750492e-01 | 0.426 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 3.750821e-01 | 0.426 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 3.815861e-01 | 0.418 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 3.815861e-01 | 0.418 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 3.815861e-01 | 0.418 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 3.815861e-01 | 0.418 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 3.815861e-01 | 0.418 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 3.815861e-01 | 0.418 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 3.815861e-01 | 0.418 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 3.861369e-01 | 0.413 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 3.880229e-01 | 0.411 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 3.880229e-01 | 0.411 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 3.898141e-01 | 0.409 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 3.934815e-01 | 0.405 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 3.934815e-01 | 0.405 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 3.934815e-01 | 0.405 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 3.943930e-01 | 0.404 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 3.943930e-01 | 0.404 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.943930e-01 | 0.404 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 4.006973e-01 | 0.397 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 4.044239e-01 | 0.393 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 4.044239e-01 | 0.393 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 4.044239e-01 | 0.393 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 4.069363e-01 | 0.390 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 4.131107e-01 | 0.384 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 4.152723e-01 | 0.382 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 4.152723e-01 | 0.382 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 4.192213e-01 | 0.378 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 4.192213e-01 | 0.378 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 4.192213e-01 | 0.378 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 4.224500e-01 | 0.374 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 4.252686e-01 | 0.371 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 4.252686e-01 | 0.371 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 4.252686e-01 | 0.371 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 4.295827e-01 | 0.367 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 4.312532e-01 | 0.365 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 4.312532e-01 | 0.365 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 4.371760e-01 | 0.359 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 4.371760e-01 | 0.359 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 4.430374e-01 | 0.354 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 4.488382e-01 | 0.348 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 4.488382e-01 | 0.348 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 4.545788e-01 | 0.342 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 4.545788e-01 | 0.342 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.576393e-01 | 0.339 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 4.602601e-01 | 0.337 | 0 | 0 |
| Immune System | R-HSA-168256 | 4.618925e-01 | 0.335 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 4.658825e-01 | 0.332 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 4.658825e-01 | 0.332 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 4.714467e-01 | 0.327 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 4.714467e-01 | 0.327 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 4.747691e-01 | 0.324 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 4.768836e-01 | 0.322 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 4.769532e-01 | 0.322 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 4.815297e-01 | 0.317 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 4.824028e-01 | 0.317 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 4.848901e-01 | 0.314 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 4.877959e-01 | 0.312 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 4.877959e-01 | 0.312 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 4.877959e-01 | 0.312 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 4.882370e-01 | 0.311 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 4.882370e-01 | 0.311 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 4.882370e-01 | 0.311 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 4.915705e-01 | 0.308 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 4.931331e-01 | 0.307 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 4.931331e-01 | 0.307 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 4.931331e-01 | 0.307 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 4.981966e-01 | 0.303 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 4.984151e-01 | 0.302 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 4.984151e-01 | 0.302 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 4.995957e-01 | 0.301 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 5.036423e-01 | 0.298 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 5.088154e-01 | 0.293 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 5.139348e-01 | 0.289 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 5.139348e-01 | 0.289 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 5.145204e-01 | 0.289 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 5.177432e-01 | 0.286 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 5.190013e-01 | 0.285 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 5.190013e-01 | 0.285 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 5.209519e-01 | 0.283 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 5.240152e-01 | 0.281 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 5.240152e-01 | 0.281 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 5.240152e-01 | 0.281 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 5.289772e-01 | 0.277 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 5.304927e-01 | 0.275 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 5.387474e-01 | 0.269 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 5.435567e-01 | 0.265 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 5.435567e-01 | 0.265 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 5.461069e-01 | 0.263 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 5.461069e-01 | 0.263 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 5.483161e-01 | 0.261 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 5.522511e-01 | 0.258 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 5.576875e-01 | 0.254 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 5.623005e-01 | 0.250 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 5.623005e-01 | 0.250 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 5.623005e-01 | 0.250 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 5.668656e-01 | 0.247 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 5.668656e-01 | 0.247 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.668656e-01 | 0.247 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 5.713834e-01 | 0.243 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 5.713834e-01 | 0.243 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 5.713834e-01 | 0.243 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 5.802789e-01 | 0.236 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 5.802789e-01 | 0.236 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 5.802789e-01 | 0.236 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 5.846576e-01 | 0.233 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 5.889909e-01 | 0.230 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 5.907573e-01 | 0.229 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 5.932793e-01 | 0.227 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 5.932793e-01 | 0.227 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 5.932793e-01 | 0.227 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.938617e-01 | 0.226 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 5.992888e-01 | 0.222 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 6.058793e-01 | 0.218 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 6.058793e-01 | 0.218 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 6.058837e-01 | 0.218 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 6.140630e-01 | 0.212 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 6.180912e-01 | 0.209 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 6.220777e-01 | 0.206 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 6.260228e-01 | 0.203 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 6.260228e-01 | 0.203 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 6.260228e-01 | 0.203 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.299269e-01 | 0.201 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 6.299269e-01 | 0.201 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 6.337906e-01 | 0.198 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 6.376141e-01 | 0.195 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 6.376141e-01 | 0.195 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 6.403898e-01 | 0.194 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 6.425413e-01 | 0.192 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 6.451195e-01 | 0.190 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 6.502320e-01 | 0.187 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 6.561446e-01 | 0.183 | 0 | 0 |
| Protein folding | R-HSA-391251 | 6.561446e-01 | 0.183 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 6.668076e-01 | 0.176 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 6.676687e-01 | 0.175 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 6.702883e-01 | 0.174 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 6.702883e-01 | 0.174 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 6.737329e-01 | 0.172 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 6.737329e-01 | 0.172 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 6.737329e-01 | 0.172 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 6.737329e-01 | 0.172 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 6.737329e-01 | 0.172 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.737329e-01 | 0.172 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 6.749255e-01 | 0.171 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 6.749255e-01 | 0.171 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 6.805152e-01 | 0.167 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 6.805152e-01 | 0.167 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 6.813982e-01 | 0.167 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 6.838536e-01 | 0.165 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 6.844019e-01 | 0.165 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 6.871573e-01 | 0.163 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 6.871573e-01 | 0.163 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 6.904267e-01 | 0.161 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 6.904267e-01 | 0.161 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 6.907790e-01 | 0.161 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 6.964579e-01 | 0.157 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 6.968639e-01 | 0.157 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 6.968639e-01 | 0.157 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 7.000325e-01 | 0.155 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 7.000325e-01 | 0.155 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 7.062711e-01 | 0.151 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 7.071101e-01 | 0.151 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 7.093049e-01 | 0.149 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 7.093419e-01 | 0.149 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 7.112184e-01 | 0.148 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 7.123808e-01 | 0.147 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 7.183641e-01 | 0.144 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 7.183641e-01 | 0.144 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 7.213092e-01 | 0.142 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 7.213092e-01 | 0.142 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 7.271079e-01 | 0.138 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 7.355817e-01 | 0.133 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 7.373500e-01 | 0.132 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 7.383478e-01 | 0.132 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 7.410851e-01 | 0.130 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 7.464746e-01 | 0.127 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 7.464746e-01 | 0.127 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 7.464746e-01 | 0.127 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 7.503943e-01 | 0.125 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 7.533135e-01 | 0.123 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 7.569214e-01 | 0.121 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 7.582116e-01 | 0.120 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 7.619831e-01 | 0.118 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 7.644746e-01 | 0.117 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 7.741838e-01 | 0.111 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 7.880065e-01 | 0.103 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 7.902270e-01 | 0.102 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 8.009878e-01 | 0.096 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 8.030732e-01 | 0.095 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 8.048433e-01 | 0.094 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 8.139186e-01 | 0.089 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 8.170750e-01 | 0.088 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 8.227685e-01 | 0.085 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 8.235815e-01 | 0.084 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 8.235815e-01 | 0.084 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 8.318688e-01 | 0.080 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 8.318688e-01 | 0.080 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 8.336324e-01 | 0.079 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 8.371045e-01 | 0.077 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.371045e-01 | 0.077 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.405046e-01 | 0.075 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 8.421780e-01 | 0.075 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 8.459703e-01 | 0.073 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 8.518586e-01 | 0.070 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 8.518586e-01 | 0.070 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 8.529734e-01 | 0.069 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.564752e-01 | 0.067 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 8.624089e-01 | 0.064 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 8.735546e-01 | 0.059 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 8.748831e-01 | 0.058 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 8.813205e-01 | 0.055 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 8.862325e-01 | 0.052 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.018860e-01 | 0.045 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 9.126667e-01 | 0.040 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 9.126667e-01 | 0.040 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.212712e-01 | 0.036 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.270566e-01 | 0.033 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.293392e-01 | 0.032 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 9.395050e-01 | 0.027 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.397299e-01 | 0.027 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.496806e-01 | 0.022 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 9.517737e-01 | 0.021 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.533286e-01 | 0.021 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.545296e-01 | 0.020 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.734250e-01 | 0.012 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.778322e-01 | 0.010 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.826602e-01 | 0.008 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.859992e-01 | 0.006 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.875545e-01 | 0.005 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.891725e-01 | 0.005 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.907812e-01 | 0.004 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 9.912627e-01 | 0.004 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.935321e-01 | 0.003 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 9.984780e-01 | 0.001 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 9.988678e-01 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.988890e-01 | 0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 9.999823e-01 | 0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | 0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.110223e-16 | 15.955 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 2.220446e-15 | 14.654 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 5.018208e-14 | 13.299 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 1.393330e-13 | 12.856 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 1.393330e-13 | 12.856 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 2.614575e-13 | 12.583 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 3.148592e-13 | 12.502 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 4.346523e-13 | 12.362 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 4.346523e-13 | 12.362 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 6.284973e-13 | 12.202 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 8.465451e-13 | 12.072 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 8.286705e-13 | 12.082 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.410427e-12 | 11.851 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 1.410427e-12 | 11.851 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.746603e-12 | 11.758 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 2.338463e-12 | 11.631 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 2.983835e-12 | 11.525 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 2.983835e-12 | 11.525 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 3.026357e-12 | 11.519 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.339995e-12 | 11.476 | 0 | 0 |
| Depurination | R-HSA-73927 | 3.785749e-12 | 11.422 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 3.787637e-12 | 11.422 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 4.716338e-12 | 11.326 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 4.716338e-12 | 11.326 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 5.996981e-12 | 11.222 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 5.996981e-12 | 11.222 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 6.271872e-12 | 11.203 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 7.490897e-12 | 11.125 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 7.490897e-12 | 11.125 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.152367e-11 | 10.938 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.152367e-11 | 10.938 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 1.419753e-11 | 10.848 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 1.693123e-11 | 10.771 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 2.128242e-11 | 10.672 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 2.128242e-11 | 10.672 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 2.590228e-11 | 10.587 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 2.872635e-11 | 10.542 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 3.794187e-11 | 10.421 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 6.553724e-11 | 10.184 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 6.429968e-11 | 10.192 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 7.812717e-11 | 10.107 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 8.901602e-11 | 10.051 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 1.100249e-10 | 9.959 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.300021e-10 | 9.886 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 1.396593e-10 | 9.855 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.477979e-10 | 9.830 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 2.109865e-10 | 9.676 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 2.466700e-10 | 9.608 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 2.876828e-10 | 9.541 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 4.128076e-10 | 9.384 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 3.885431e-10 | 9.411 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 3.885431e-10 | 9.411 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 4.916043e-10 | 9.308 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 5.545926e-10 | 9.256 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 5.533258e-10 | 9.257 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 6.902401e-10 | 9.161 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 7.927713e-10 | 9.101 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 8.861504e-10 | 9.052 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 9.799733e-10 | 9.009 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 1.187362e-09 | 8.925 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.187362e-09 | 8.925 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.216200e-09 | 8.915 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.353517e-09 | 8.869 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.369694e-09 | 8.863 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.723438e-09 | 8.764 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.096872e-09 | 8.678 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.096872e-09 | 8.678 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 2.096872e-09 | 8.678 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 2.539531e-09 | 8.595 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 3.121746e-09 | 8.506 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 3.230064e-09 | 8.491 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 3.557801e-09 | 8.449 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 4.083988e-09 | 8.389 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 4.582355e-09 | 8.339 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 4.582355e-09 | 8.339 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 4.780384e-09 | 8.321 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 4.803849e-09 | 8.318 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 4.872317e-09 | 8.312 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 5.134403e-09 | 8.290 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 1.009452e-08 | 7.996 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 1.349041e-08 | 7.870 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.469936e-08 | 7.833 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 1.493008e-08 | 7.826 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.616203e-08 | 7.792 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 2.366446e-08 | 7.626 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 3.235341e-08 | 7.490 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 3.868943e-08 | 7.412 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 5.084483e-08 | 7.294 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 6.599298e-08 | 7.181 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 6.599298e-08 | 7.181 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 7.644399e-08 | 7.117 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 1.312798e-07 | 6.882 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 1.382617e-07 | 6.859 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.495526e-07 | 6.825 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 1.579013e-07 | 6.802 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 1.697847e-07 | 6.770 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 1.746144e-07 | 6.758 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.854779e-07 | 6.732 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 1.966930e-07 | 6.706 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 2.361509e-07 | 6.627 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 2.941902e-07 | 6.531 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 3.472055e-07 | 6.459 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 3.478969e-07 | 6.459 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 3.816197e-07 | 6.418 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 4.050725e-07 | 6.392 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 4.192766e-07 | 6.377 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 4.192766e-07 | 6.377 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 4.192766e-07 | 6.377 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 5.207393e-07 | 6.283 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 5.216925e-07 | 6.283 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 5.597632e-07 | 6.252 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 6.309100e-07 | 6.200 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 6.932828e-07 | 6.159 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 8.700092e-07 | 6.060 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.476184e-06 | 5.831 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.983453e-06 | 5.703 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.902568e-06 | 5.721 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.296376e-06 | 5.639 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 2.850616e-06 | 5.545 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 3.011790e-06 | 5.521 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 3.496962e-06 | 5.456 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 3.544227e-06 | 5.450 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 3.791888e-06 | 5.421 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 3.791888e-06 | 5.421 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 4.030678e-06 | 5.395 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 4.232957e-06 | 5.373 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 5.066114e-06 | 5.295 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 6.902626e-06 | 5.161 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 8.087064e-06 | 5.092 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 9.799258e-06 | 5.009 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.170173e-05 | 4.932 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.732419e-05 | 4.761 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 4.619727e-05 | 4.335 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 6.331693e-05 | 4.198 | 1 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 7.292000e-05 | 4.137 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 9.293887e-05 | 4.032 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 1.124608e-04 | 3.949 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 1.200577e-04 | 3.921 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.210189e-04 | 3.917 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 1.285885e-04 | 3.891 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.293969e-04 | 3.888 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.295817e-04 | 3.887 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.310976e-04 | 3.882 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.504301e-04 | 3.823 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.683895e-04 | 3.774 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.744691e-04 | 3.758 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 2.025036e-04 | 3.694 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 2.033911e-04 | 3.692 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 2.224272e-04 | 3.653 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 2.922003e-04 | 3.534 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 3.153947e-04 | 3.501 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 3.153947e-04 | 3.501 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 3.153947e-04 | 3.501 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 3.153947e-04 | 3.501 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 3.172046e-04 | 3.499 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 4.142026e-04 | 3.383 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 4.721293e-04 | 3.326 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 4.997643e-04 | 3.301 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 5.239003e-04 | 3.281 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 5.876298e-04 | 3.231 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 6.365737e-04 | 3.196 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 6.747754e-04 | 3.171 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 8.429369e-04 | 3.074 | 1 | 0 |
| DNA Repair | R-HSA-73894 | 8.682801e-04 | 3.061 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 7.955199e-04 | 3.099 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 7.773926e-04 | 3.109 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.072031e-03 | 2.970 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.072031e-03 | 2.970 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.179532e-03 | 2.928 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 1.179532e-03 | 2.928 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.210983e-03 | 2.917 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 1.249191e-03 | 2.903 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 1.285250e-03 | 2.891 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.359639e-03 | 2.867 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.362761e-03 | 2.866 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.443811e-03 | 2.840 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 1.708065e-03 | 2.767 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 1.803555e-03 | 2.744 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.902900e-03 | 2.721 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 2.011561e-03 | 2.696 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 2.113523e-03 | 2.675 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 2.399800e-03 | 2.620 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 3.228501e-03 | 2.491 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 3.240019e-03 | 2.489 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 3.276537e-03 | 2.485 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 3.429359e-03 | 2.465 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 3.764950e-03 | 2.424 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 4.092182e-03 | 2.388 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 4.132075e-03 | 2.384 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 4.165586e-03 | 2.380 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 4.312812e-03 | 2.365 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 4.455812e-03 | 2.351 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 5.003145e-03 | 2.301 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 6.353295e-03 | 2.197 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 5.542957e-03 | 2.256 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 5.287414e-03 | 2.277 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 6.870236e-03 | 2.163 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 5.287414e-03 | 2.277 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 5.585792e-03 | 2.253 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 6.562259e-03 | 2.183 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 6.822932e-03 | 2.166 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 6.876714e-03 | 2.163 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 7.054420e-03 | 2.152 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 7.134629e-03 | 2.147 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 7.225822e-03 | 2.141 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 7.394421e-03 | 2.131 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 7.508431e-03 | 2.124 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 7.508431e-03 | 2.124 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 8.750825e-03 | 2.058 | 0 | 0 |
| Disease | R-HSA-1643685 | 1.033761e-02 | 1.986 | 0 | 0 |
| Drug resistance of PDGFR mutants | R-HSA-9674415 | 1.062473e-02 | 1.974 | 0 | 0 |
| PDGFR mutants bind TKIs | R-HSA-9674428 | 1.062473e-02 | 1.974 | 0 | 0 |
| Sorafenib-resistant PDGFR mutants | R-HSA-9674404 | 1.062473e-02 | 1.974 | 0 | 0 |
| Regorafenib-resistant PDGFR mutants | R-HSA-9674403 | 1.062473e-02 | 1.974 | 0 | 0 |
| Sunitinib-resistant PDGFR mutants | R-HSA-9674401 | 1.062473e-02 | 1.974 | 0 | 0 |
| Imatinib-resistant PDGFR mutants | R-HSA-9674396 | 1.062473e-02 | 1.974 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.065989e-02 | 1.972 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.091040e-02 | 1.962 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.109331e-02 | 1.955 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 1.204754e-02 | 1.919 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 1.298209e-02 | 1.887 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.309120e-02 | 1.883 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.318281e-02 | 1.880 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.339976e-02 | 1.873 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 1.358014e-02 | 1.867 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.380687e-02 | 1.860 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.519422e-02 | 1.818 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 1.522055e-02 | 1.818 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 1.620408e-02 | 1.790 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.620408e-02 | 1.790 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.659760e-02 | 1.780 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.792990e-02 | 1.746 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 1.873414e-02 | 1.727 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 1.884469e-02 | 1.725 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.919021e-02 | 1.717 | 1 | 0 |
| Somitogenesis | R-HSA-9824272 | 1.968444e-02 | 1.706 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 2.160228e-02 | 1.666 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 2.166369e-02 | 1.664 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 2.260964e-02 | 1.646 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 2.354538e-02 | 1.628 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.354538e-02 | 1.628 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 2.559087e-02 | 1.592 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 2.663810e-02 | 1.574 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.717225e-02 | 1.566 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 2.763688e-02 | 1.559 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.763688e-02 | 1.559 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 3.153865e-02 | 1.501 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 4.183019e-02 | 1.379 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 4.183019e-02 | 1.379 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 4.183019e-02 | 1.379 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 4.183019e-02 | 1.379 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 4.183019e-02 | 1.379 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 4.183019e-02 | 1.379 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 4.183019e-02 | 1.379 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 4.183019e-02 | 1.379 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 4.183019e-02 | 1.379 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 4.183019e-02 | 1.379 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 4.183019e-02 | 1.379 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 2.978199e-02 | 1.526 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 3.659544e-02 | 1.437 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 3.659544e-02 | 1.437 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 3.898743e-02 | 1.409 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 4.183019e-02 | 1.379 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 4.066984e-02 | 1.391 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.978199e-02 | 1.526 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 3.570582e-02 | 1.447 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 3.584775e-02 | 1.446 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 3.059229e-02 | 1.514 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.978199e-02 | 1.526 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 3.898743e-02 | 1.409 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 3.199117e-02 | 1.495 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 2.945604e-02 | 1.531 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 3.844506e-02 | 1.415 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 2.978199e-02 | 1.526 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 4.275989e-02 | 1.369 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 4.394359e-02 | 1.357 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 4.394359e-02 | 1.357 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 4.394359e-02 | 1.357 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 4.394359e-02 | 1.357 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 4.711897e-02 | 1.327 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 4.911953e-02 | 1.309 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 4.927231e-02 | 1.307 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 5.051273e-02 | 1.297 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 5.201300e-02 | 1.284 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 5.201300e-02 | 1.284 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 5.427524e-02 | 1.265 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 5.727074e-02 | 1.242 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 6.008561e-02 | 1.221 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 6.161924e-02 | 1.210 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 6.208821e-02 | 1.207 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 6.301807e-02 | 1.201 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 6.585409e-02 | 1.181 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 6.585409e-02 | 1.181 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 6.880514e-02 | 1.162 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 7.179904e-02 | 1.144 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 7.179904e-02 | 1.144 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 7.179904e-02 | 1.144 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 7.205696e-02 | 1.142 | 0 | 0 |
| Trafficking of myristoylated proteins to the cilium | R-HSA-5624138 | 7.205696e-02 | 1.142 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 7.205696e-02 | 1.142 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 7.791051e-02 | 1.108 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 8.192037e-02 | 1.087 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 8.192037e-02 | 1.087 | 0 | 0 |
| Cam-PDE 1 activation | R-HSA-111957 | 8.192037e-02 | 1.087 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 8.192037e-02 | 1.087 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 8.192037e-02 | 1.087 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.013356e-01 | 0.994 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 1.013356e-01 | 0.994 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 1.013356e-01 | 0.994 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 1.108895e-01 | 0.955 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 1.108895e-01 | 0.955 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 1.203425e-01 | 0.920 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 1.296956e-01 | 0.887 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 1.296956e-01 | 0.887 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.571656e-01 | 0.804 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.425669e-01 | 0.846 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.499062e-01 | 0.824 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 1.389272e-01 | 0.857 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 1.605806e-01 | 0.794 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.648009e-01 | 0.783 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 1.203425e-01 | 0.920 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.573196e-01 | 0.803 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 1.108895e-01 | 0.955 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.296956e-01 | 0.887 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.389497e-01 | 0.857 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.296956e-01 | 0.887 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 1.571656e-01 | 0.804 | 0 | 0 |
| Microbial factors inhibit CASP4 activity | R-HSA-9956593 | 1.661294e-01 | 0.780 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 8.726152e-02 | 1.059 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 8.417891e-02 | 1.075 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 9.059497e-02 | 1.043 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 1.013356e-01 | 0.994 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.203425e-01 | 0.920 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.004764e-01 | 0.998 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.689632e-02 | 1.014 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 1.106410e-01 | 0.956 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 9.488108e-02 | 1.023 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 1.203425e-01 | 0.920 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 1.389497e-01 | 0.857 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 1.389497e-01 | 0.857 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.571656e-01 | 0.804 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 1.661294e-01 | 0.780 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.385555e-02 | 1.028 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 1.106410e-01 | 0.956 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 1.610522e-01 | 0.793 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 1.610522e-01 | 0.793 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 1.661294e-01 | 0.780 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 1.203425e-01 | 0.920 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 1.011912e-01 | 0.995 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 8.417891e-02 | 1.075 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 1.108895e-01 | 0.955 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 1.203425e-01 | 0.920 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 1.296956e-01 | 0.887 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.481061e-01 | 0.829 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 1.661294e-01 | 0.780 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 9.059497e-02 | 1.043 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 8.443535e-02 | 1.073 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 9.517573e-02 | 1.021 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.536040e-01 | 0.814 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 9.356641e-02 | 1.029 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 1.245872e-01 | 0.905 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 9.059497e-02 | 1.043 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 1.499062e-01 | 0.824 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 1.296956e-01 | 0.887 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.689632e-02 | 1.014 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 1.051885e-01 | 0.978 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 1.051885e-01 | 0.978 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 1.481061e-01 | 0.829 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 1.101318e-01 | 0.958 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.001026e-01 | 1.000 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 1.115761e-01 | 0.952 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.172559e-01 | 0.931 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 9.682431e-02 | 1.014 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 1.175612e-01 | 0.930 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.190403e-01 | 0.924 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 9.167954e-02 | 1.038 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 1.203425e-01 | 0.920 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 1.571656e-01 | 0.804 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 1.571656e-01 | 0.804 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 1.571656e-01 | 0.804 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 1.072231e-01 | 0.970 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.140874e-01 | 0.943 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 8.417891e-02 | 1.075 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 1.106410e-01 | 0.956 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.434470e-01 | 0.843 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 1.203425e-01 | 0.920 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 1.245872e-01 | 0.905 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 1.077737e-01 | 0.967 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 1.479484e-01 | 0.830 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.203425e-01 | 0.920 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 1.389497e-01 | 0.857 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 8.417891e-02 | 1.075 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 1.661294e-01 | 0.780 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.499062e-01 | 0.824 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.059901e-02 | 1.043 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 1.145187e-01 | 0.941 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.536040e-01 | 0.814 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 1.284696e-01 | 0.891 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.068026e-01 | 0.971 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.659242e-01 | 0.780 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.004764e-01 | 0.998 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.137228e-01 | 0.944 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 1.038345e-01 | 0.984 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 9.267847e-02 | 1.033 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 1.033669e-01 | 0.986 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.525344e-01 | 0.817 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 1.389497e-01 | 0.857 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 1.038345e-01 | 0.984 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 1.072231e-01 | 0.970 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 1.685650e-01 | 0.773 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 1.723438e-01 | 0.764 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 1.723438e-01 | 0.764 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.749983e-01 | 0.757 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 1.749983e-01 | 0.757 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 1.749983e-01 | 0.757 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.749983e-01 | 0.757 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 1.837735e-01 | 0.736 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 1.837735e-01 | 0.736 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 1.837735e-01 | 0.736 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 1.837735e-01 | 0.736 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 1.837735e-01 | 0.736 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 1.914328e-01 | 0.718 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 1.921250e-01 | 0.716 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.924559e-01 | 0.716 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.924559e-01 | 0.716 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 1.924559e-01 | 0.716 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 1.952848e-01 | 0.709 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 1.952848e-01 | 0.709 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 1.991466e-01 | 0.701 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 2.010464e-01 | 0.697 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 2.010464e-01 | 0.697 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 2.010464e-01 | 0.697 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.010464e-01 | 0.697 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 2.030176e-01 | 0.692 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 2.068972e-01 | 0.684 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 2.068972e-01 | 0.684 | 0 | 0 |
| Translation | R-HSA-72766 | 2.077198e-01 | 0.683 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 2.095461e-01 | 0.679 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 2.095461e-01 | 0.679 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 2.095461e-01 | 0.679 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 2.143742e-01 | 0.669 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 2.146797e-01 | 0.668 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 2.146797e-01 | 0.668 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 2.179559e-01 | 0.662 | 0 | 0 |
| PKA activation | R-HSA-163615 | 2.179559e-01 | 0.662 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.179559e-01 | 0.662 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 2.179559e-01 | 0.662 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 2.179559e-01 | 0.662 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 2.224892e-01 | 0.653 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 2.262767e-01 | 0.645 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 2.264027e-01 | 0.645 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 2.342443e-01 | 0.630 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 2.342443e-01 | 0.630 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 2.345095e-01 | 0.630 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 2.345095e-01 | 0.630 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 2.345095e-01 | 0.630 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 2.362865e-01 | 0.627 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 2.362865e-01 | 0.627 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 2.362865e-01 | 0.627 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 2.381713e-01 | 0.623 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 2.421018e-01 | 0.616 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 2.421018e-01 | 0.616 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 2.426552e-01 | 0.615 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 2.426552e-01 | 0.615 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.426552e-01 | 0.615 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 2.426552e-01 | 0.615 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.480880e-01 | 0.605 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 2.499711e-01 | 0.602 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 2.507147e-01 | 0.601 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 2.507147e-01 | 0.601 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.507147e-01 | 0.601 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 2.507147e-01 | 0.601 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 2.507147e-01 | 0.601 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.507147e-01 | 0.601 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 2.586890e-01 | 0.587 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.586890e-01 | 0.587 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 2.647312e-01 | 0.577 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 2.657294e-01 | 0.576 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 2.657294e-01 | 0.576 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 2.657294e-01 | 0.576 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 2.665789e-01 | 0.574 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 2.665789e-01 | 0.574 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 2.665789e-01 | 0.574 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 2.665789e-01 | 0.574 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.743852e-01 | 0.562 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 2.743852e-01 | 0.562 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 2.743852e-01 | 0.562 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 2.743852e-01 | 0.562 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.743852e-01 | 0.562 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.743852e-01 | 0.562 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 2.762308e-01 | 0.559 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 2.775505e-01 | 0.557 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 2.821090e-01 | 0.550 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 2.821090e-01 | 0.550 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 2.821090e-01 | 0.550 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 2.821090e-01 | 0.550 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 2.821090e-01 | 0.550 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 2.897510e-01 | 0.538 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 2.897510e-01 | 0.538 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 2.897510e-01 | 0.538 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 2.897510e-01 | 0.538 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 2.906745e-01 | 0.537 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.973122e-01 | 0.527 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.973122e-01 | 0.527 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 2.973122e-01 | 0.527 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 2.973122e-01 | 0.527 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 2.973122e-01 | 0.527 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 3.011488e-01 | 0.521 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 3.047933e-01 | 0.516 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 3.047933e-01 | 0.516 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 3.047933e-01 | 0.516 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 3.047933e-01 | 0.516 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 3.047933e-01 | 0.516 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 3.047933e-01 | 0.516 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 3.080768e-01 | 0.511 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 3.121952e-01 | 0.506 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 3.121952e-01 | 0.506 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 3.121952e-01 | 0.506 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 3.121952e-01 | 0.506 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 3.121952e-01 | 0.506 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 3.195188e-01 | 0.496 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 3.195188e-01 | 0.496 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 3.195188e-01 | 0.496 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 3.195188e-01 | 0.496 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.207192e-01 | 0.494 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 3.246186e-01 | 0.489 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 3.267648e-01 | 0.486 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 3.267648e-01 | 0.486 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 3.267648e-01 | 0.486 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 3.267648e-01 | 0.486 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 3.267648e-01 | 0.486 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 3.267648e-01 | 0.486 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 3.267648e-01 | 0.486 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 3.267648e-01 | 0.486 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 3.313346e-01 | 0.480 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 3.324001e-01 | 0.478 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 3.324001e-01 | 0.478 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 3.339342e-01 | 0.476 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.339342e-01 | 0.476 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 3.362815e-01 | 0.473 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 3.371497e-01 | 0.472 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 3.371497e-01 | 0.472 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 3.387964e-01 | 0.470 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 3.401564e-01 | 0.468 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 3.410276e-01 | 0.467 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 3.410276e-01 | 0.467 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 3.410276e-01 | 0.467 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.410276e-01 | 0.467 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 3.410276e-01 | 0.467 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 3.410276e-01 | 0.467 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 3.410276e-01 | 0.467 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 3.478851e-01 | 0.459 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 3.480459e-01 | 0.458 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 3.480459e-01 | 0.458 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 3.480459e-01 | 0.458 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.480459e-01 | 0.458 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 3.545755e-01 | 0.450 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 3.549899e-01 | 0.450 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 3.549899e-01 | 0.450 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 3.549899e-01 | 0.450 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 3.618603e-01 | 0.441 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 3.618603e-01 | 0.441 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 3.618603e-01 | 0.441 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.618603e-01 | 0.441 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 3.618603e-01 | 0.441 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 3.618603e-01 | 0.441 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 3.670714e-01 | 0.435 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 3.670714e-01 | 0.435 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 3.686580e-01 | 0.433 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 3.686580e-01 | 0.433 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 3.686580e-01 | 0.433 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 3.686580e-01 | 0.433 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 3.708833e-01 | 0.431 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 3.753837e-01 | 0.426 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 3.753837e-01 | 0.426 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 3.753837e-01 | 0.426 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 3.753837e-01 | 0.426 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 3.753837e-01 | 0.426 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 3.753837e-01 | 0.426 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 3.820382e-01 | 0.418 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 3.886222e-01 | 0.410 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 3.886222e-01 | 0.410 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 3.886222e-01 | 0.410 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 3.886222e-01 | 0.410 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 3.886222e-01 | 0.410 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 3.886222e-01 | 0.410 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 3.886222e-01 | 0.410 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 3.886222e-01 | 0.410 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 3.951364e-01 | 0.403 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 3.951364e-01 | 0.403 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.951364e-01 | 0.403 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 3.951364e-01 | 0.403 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 3.951364e-01 | 0.403 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 3.951364e-01 | 0.403 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 3.951364e-01 | 0.403 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 3.951364e-01 | 0.403 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 3.990329e-01 | 0.399 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 4.010342e-01 | 0.397 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 4.015816e-01 | 0.396 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 4.015816e-01 | 0.396 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 4.015816e-01 | 0.396 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 4.015816e-01 | 0.396 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 4.015816e-01 | 0.396 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 4.028356e-01 | 0.395 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 4.047567e-01 | 0.393 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 4.047567e-01 | 0.393 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 4.079586e-01 | 0.389 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 4.079586e-01 | 0.389 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 4.079586e-01 | 0.389 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 4.079586e-01 | 0.389 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 4.079586e-01 | 0.389 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 4.079586e-01 | 0.389 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 4.084683e-01 | 0.389 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 4.121687e-01 | 0.385 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 4.142679e-01 | 0.383 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 4.142679e-01 | 0.383 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 4.142679e-01 | 0.383 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 4.205105e-01 | 0.376 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 4.205105e-01 | 0.376 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 4.232013e-01 | 0.373 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 4.232013e-01 | 0.373 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 4.266868e-01 | 0.370 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 4.266868e-01 | 0.370 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 4.266868e-01 | 0.370 | 0 | 0 |
| Methylation | R-HSA-156581 | 4.266868e-01 | 0.370 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 4.327978e-01 | 0.364 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 4.327978e-01 | 0.364 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 4.327978e-01 | 0.364 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 4.327978e-01 | 0.364 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 4.327978e-01 | 0.364 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 4.327978e-01 | 0.364 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 4.388439e-01 | 0.358 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 4.388439e-01 | 0.358 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 4.388439e-01 | 0.358 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 4.388439e-01 | 0.358 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 4.388439e-01 | 0.358 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 4.388439e-01 | 0.358 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 4.388439e-01 | 0.358 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 4.448260e-01 | 0.352 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 4.507447e-01 | 0.346 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 4.507447e-01 | 0.346 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 4.566006e-01 | 0.340 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 4.566006e-01 | 0.340 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 4.591828e-01 | 0.338 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 4.623945e-01 | 0.335 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 4.662241e-01 | 0.331 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 4.681270e-01 | 0.330 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 4.681270e-01 | 0.330 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 4.681270e-01 | 0.330 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 4.681270e-01 | 0.330 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 4.681270e-01 | 0.330 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 4.697245e-01 | 0.328 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 4.737986e-01 | 0.324 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 4.737986e-01 | 0.324 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.737986e-01 | 0.324 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 4.737986e-01 | 0.324 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 4.737986e-01 | 0.324 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 4.758645e-01 | 0.323 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 4.794102e-01 | 0.319 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 4.794102e-01 | 0.319 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 4.794102e-01 | 0.319 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 4.794102e-01 | 0.319 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 4.794102e-01 | 0.319 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 4.849622e-01 | 0.314 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 4.870201e-01 | 0.312 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 4.904554e-01 | 0.309 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 4.924781e-01 | 0.308 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 4.958903e-01 | 0.305 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 4.958903e-01 | 0.305 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 4.958903e-01 | 0.305 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 4.977068e-01 | 0.303 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 5.039631e-01 | 0.298 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 5.118517e-01 | 0.291 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 5.170597e-01 | 0.286 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 5.170597e-01 | 0.286 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 5.170597e-01 | 0.286 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 5.222124e-01 | 0.282 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 5.222124e-01 | 0.282 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 5.222124e-01 | 0.282 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 5.238148e-01 | 0.281 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 5.273105e-01 | 0.278 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 5.273105e-01 | 0.278 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 5.273105e-01 | 0.278 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 5.273105e-01 | 0.278 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 5.323545e-01 | 0.274 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 5.323545e-01 | 0.274 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 5.323545e-01 | 0.274 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 5.367519e-01 | 0.270 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 5.367519e-01 | 0.270 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 5.373450e-01 | 0.270 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 5.373450e-01 | 0.270 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 5.422826e-01 | 0.266 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 5.431300e-01 | 0.265 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 5.431300e-01 | 0.265 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 5.520010e-01 | 0.258 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 5.525831e-01 | 0.258 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 5.567830e-01 | 0.254 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 5.661954e-01 | 0.247 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 5.661954e-01 | 0.247 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 5.661954e-01 | 0.247 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 5.680318e-01 | 0.246 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 5.680318e-01 | 0.246 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 5.708267e-01 | 0.243 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 5.708267e-01 | 0.243 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 5.708267e-01 | 0.243 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 5.708267e-01 | 0.243 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 5.754089e-01 | 0.240 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 5.754089e-01 | 0.240 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 5.799425e-01 | 0.237 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 5.799425e-01 | 0.237 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 5.844280e-01 | 0.233 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 6.006591e-01 | 0.221 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 6.006591e-01 | 0.221 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 6.018985e-01 | 0.220 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 6.018985e-01 | 0.220 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 6.018985e-01 | 0.220 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 6.018985e-01 | 0.220 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 6.061508e-01 | 0.217 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 6.103580e-01 | 0.214 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 6.103580e-01 | 0.214 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 6.145204e-01 | 0.211 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 6.227132e-01 | 0.206 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 6.227132e-01 | 0.206 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 6.267444e-01 | 0.203 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 6.307328e-01 | 0.200 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.346789e-01 | 0.197 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 6.385830e-01 | 0.195 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 6.424456e-01 | 0.192 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 6.424456e-01 | 0.192 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 6.424456e-01 | 0.192 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 6.462672e-01 | 0.190 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 6.500050e-01 | 0.187 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 6.500481e-01 | 0.187 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 6.537889e-01 | 0.185 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 6.683587e-01 | 0.175 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 6.719048e-01 | 0.173 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 6.754133e-01 | 0.170 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 6.788845e-01 | 0.168 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 6.857164e-01 | 0.164 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 6.873493e-01 | 0.163 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 6.890780e-01 | 0.162 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 6.890780e-01 | 0.162 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 6.956944e-01 | 0.158 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 6.989499e-01 | 0.156 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 7.021707e-01 | 0.154 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 7.085100e-01 | 0.150 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 7.147152e-01 | 0.146 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 7.177683e-01 | 0.144 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 7.207889e-01 | 0.142 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 7.207889e-01 | 0.142 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 7.207889e-01 | 0.142 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 7.237775e-01 | 0.140 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.237775e-01 | 0.140 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 7.354168e-01 | 0.133 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 7.354168e-01 | 0.133 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 7.433215e-01 | 0.129 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 7.438251e-01 | 0.129 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 7.492825e-01 | 0.125 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 7.522541e-01 | 0.124 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 7.546243e-01 | 0.122 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 7.598530e-01 | 0.119 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 7.618750e-01 | 0.118 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 7.649708e-01 | 0.116 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 7.699803e-01 | 0.114 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 7.772960e-01 | 0.109 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 7.801542e-01 | 0.108 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 7.843804e-01 | 0.105 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 8.064158e-01 | 0.093 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 8.105465e-01 | 0.091 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 8.105465e-01 | 0.091 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 8.125788e-01 | 0.090 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 8.145971e-01 | 0.089 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 8.243257e-01 | 0.084 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 8.299216e-01 | 0.081 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 8.299216e-01 | 0.081 | 0 | 0 |
| S Phase | R-HSA-69242 | 8.317473e-01 | 0.080 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 8.317473e-01 | 0.080 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 8.371081e-01 | 0.077 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 8.388571e-01 | 0.076 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 8.489655e-01 | 0.071 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 8.517932e-01 | 0.070 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.629580e-01 | 0.064 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 8.701666e-01 | 0.060 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 8.756610e-01 | 0.058 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 8.796296e-01 | 0.056 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 8.831066e-01 | 0.054 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 8.931331e-01 | 0.049 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 9.051296e-01 | 0.043 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.071623e-01 | 0.042 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 9.081623e-01 | 0.042 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 9.175919e-01 | 0.037 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.181026e-01 | 0.037 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.252522e-01 | 0.034 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.364778e-01 | 0.029 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 9.385130e-01 | 0.028 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.446229e-01 | 0.025 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 9.597574e-01 | 0.018 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.614718e-01 | 0.017 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 9.682498e-01 | 0.014 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.725238e-01 | 0.012 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.756241e-01 | 0.011 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 9.809966e-01 | 0.008 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.857566e-01 | 0.006 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.873522e-01 | 0.006 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.891515e-01 | 0.005 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 9.902786e-01 | 0.004 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.917546e-01 | 0.004 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.987742e-01 | 0.001 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.990551e-01 | 0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 9.998983e-01 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 9.999510e-01 | 0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 9.999704e-01 | 0.000 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 1.000000e+00 | 0.000 | 1 | 1 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 1.000000e+00 | 0.000 | 1 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 1.000000e+00 | 0.000 | 1 | 1 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
