FGFR4

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included
Y Sites Probabilities

Log-Odds: Y Sites / Y Background

Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown

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substrate_uniprot site source substrate_genes site_seq
A5A3E0 Y1062 Sugiyama POTEF A26C1B GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NMY6 Y147 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B sLIEIICsRtNQELQEINRVyKEMYKtDLEKDIIsDtsGDF
O00115 Y53 Sugiyama DNASE2 DNASE2A DNL2 YKLPALRGSGEAAQRGLQYKyLDEssGGWRDGRALINsPEG
O00116 Y645 Sugiyama AGPS AAG5 QWLKESIsDVGFGMLKSVKEyVDPNNIFGNRNLL_______
O00170 Y202 Sugiyama AIP XAP2 IHQEGNRLYREGHVKEAAAKyyDAIACLKNLQMKEQPGSPE
O00170 Y203 Sugiyama AIP XAP2 HQEGNRLYREGHVKEAAAKyyDAIACLKNLQMKEQPGSPEW
O00264 Y180 Sugiyama PGRMC1 HPR6.6 PGRMC FTFKYHHVGKLLKEGEEPtVysDEEEPKDEsARKND_____
O00429 Y101 Sugiyama DNM1L DLP1 DRP1 EENGVEAEEWGKFLHTKNKLyTDFDEIRQEIENETERISGN
O00469 Y444 Sugiyama PLOD2 LWSNFWGALSPDGYYARsEDyVDIVQGNRVGVWNVPYMANV
O00488 Y97 Sugiyama ZNF593 ZT86 KTHFRSKDHKKRLKQLsVEPysQEEAERAAGMGSYVPPRRL
O14602 Y35 Sugiyama EIF1AY GKNENESEKRELVFKEDGQEyAQVIKMLGNGRLEALCFDGV
O14639 Y383 Sugiyama ABLIM1 ABLIM KIAA0059 LIMAB1 sIPGsPGHtIyAKVDNEILDyKDLAAIPKVKAIYDIERPDL
O14818 Y145 Sugiyama PSMA7 HSPC RPFGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGA
O14818 Y153 Sugiyama PSMA7 HSPC IVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFLE
O14818 Y176 Sugiyama PSMA7 HSPC WKANAIGRGAKSVREFLEKNyTDEAIETDDLTIKLVIKALL
O14910 Y133 Sugiyama LIN7A MALS1 VELI1 KTDEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLKRGD
O14950 Y143 Sugiyama MYL12B MRLC2 MYLC2B LRELLttMGDRFtDEEVDELyREAPIDKKGNFNyIEFtRIL
O14950 Y156 Sugiyama MYL12B MRLC2 MYLC2B DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
O14979 Y167 Sugiyama HNRNPDL HNRPDL JKTBP DGKMFIGGLSWDTsKKDLtEyLSRFGEVVDCtIKTDPVTGR
O15067 Y538 Sugiyama PFAS KIAA0361 GAGGNGNVLKELsDPAGAIIytsRFQLGDPTLNALEIWGAE
O15230 Y81 Sugiyama LAMA5 KIAA0533 KIAA1907 SATCGEEAPARGSPRPTEDLyCKLVGGPVAGGDPNQTIRGQ
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O43172 Y31 Sugiyama PRPF4 PRP4 ATKTKAPDDLVAPVVKKPHIyyGsLEEKERERLAKGESGIL
O43172 Y32 Sugiyama PRPF4 PRP4 TKTKAPDDLVAPVVKKPHIyyGsLEEKERERLAKGESGILG
O43252 Y238 Sugiyama PAPSS1 ATPSK1 PAPSS ELLQERDIVPVDAsYEVKELyVPENKLHLAKTDAETLPALK
O43390 Y136 Sugiyama HNRNPR HNRPR QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O43390 Y376 Sugiyama HNRNPR HNRPR ILEKSFSEFGKLERVKKLKDyAFVHFEDRGAAVKAMDEMNG
O43390 Y434 Sugiyama HNRNPR HNRPR KKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGG
O43390 Y435 Sugiyama HNRNPR HNRPR KRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGGR
O43390 Y436 Sugiyama HNRNPR HNRPR RKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGGRG
O43448 Y311 Sugiyama KCNAB3 KCNA3B LITSKYDGRVPDTCRASIKGyQWLKDKVQSEDGKKQQAKVM
O43707 Y212 Sugiyama ACTN4 WKDGLAFNALIHRHRPELIEyDKLRKDDPVTNLNNAFEVAE
O43707 Y234 Sugiyama ACTN4 KLRKDDPVTNLNNAFEVAEKyLDIPKMLDAEDIVNtARPDE
O43707 Y441 Sugiyama ACTN4 KAsIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEs
O43707 Y878 Sugiyama ACTN4 DKNFITAEELRRELPPDQAEyCIARMAPyQGPDAVPGALDy
O43765 T194 Sugiyama SGTA SGT SGT1 KHVEAVAYYKKALELDPDNEtyKsNLKIAELKLREAPSPTG
O43823 Y311 Sugiyama AKAP8 AKAP95 RGFDRFGPDGTGRKRKQFQLyEEPDtKLARVDsEGDFsEND
O43852 Y185 Sugiyama CALU KDGDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNAD
O43852 Y187 Sugiyama CALU GDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNADGF
O43852 Y213 Sugiyama CALU VQEtMEDIDKNADGFIDLEEyIGDMysHDGNtDEPEWVKTE
O43852 Y263 Sugiyama CALU KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
O43852 Y47 Sugiyama CALU RVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQLtPE
O43865 Y28 Sugiyama AHCYL1 DCAL IRBIT XPVKONA PLPGVGEELKQAKEIEDAEKysFMATVTKAPKKQIQFADDM
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60361 Y37 Sugiyama NME2P1 GFRLVAMKFLPASEEHLKQHyIDLKDRPFFPGLVKYMNSGP
O60488 Y582 Sugiyama ACSL4 ACS4 FACL4 LACS4 DGCLQIIDRKKDLVKLQAGEyVsLGKVEAALKNCPLIDNIC
O60506 Y133 Sugiyama SYNCRIP HNRPQ NSAP1 ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O60506 Y373 Sugiyama SYNCRIP HNRPQ NSAP1 ILEKAFsQFGKLERVKKLKDyAFIHFDERDGAVKAMEEMNG
O60664 Y95 Sugiyama PLIN3 M6PRBP1 TIP47 VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE
O60739 Y30 Sugiyama EIF1B FDPFADATKGDDLLPAGTEDyIHIRIQQRNGRKtLttVQGI
O60814 Y38 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
O60814 Y41 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
O60814 Y43 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
O75116 Y936 Sugiyama ROCK2 KIAA0619 EITLTKADSEQLARsIAEEQysDLEKEKIMKELEIKEMMAR
O75208 Y93 Sugiyama COQ9 C16orf49 HSPC326 PSEC0129 PEssHsPPRYTDQGGEEEEDyEsEEQLQHRILTAALEFVPA
O75347 Y75 Sugiyama TBCA EILQEsRMMIPDCQRRLEAAyLDLQRILENEKDLEEAEEyK
O75347 Y94 Sugiyama TBCA AyLDLQRILENEKDLEEAEEyKEARLVLDsVKLEA______
O75369 Y902 Sugiyama FLNB FLN1L FLN3 TABP TAP VQFNsPLPGDAVKDLDIIDNyDysHtVKYtPtQQGNMQVLV
O75369 Y904 Sugiyama FLNB FLN1L FLN3 TABP TAP FNsPLPGDAVKDLDIIDNyDysHtVKYtPtQQGNMQVLVTY
O75874 Y391 Sugiyama IDH1 PICD FMTKDLAACIKGLPNVQRsDyLNTFEFMDKLGENLKIKLAQ
O94906 Y105 Sugiyama PRPF6 C20orf14 AGSLFSSGPYEKDDEEADAIyAALDKRMDERRKERREQREK
O94919 Y134 Sugiyama ENDOD1 KIAA0830 EAEAITSVNSLGSKQALNtDyLDsDyQRGQLYPFSLSSDVQ
O95297 Y263 Sugiyama MPZL1 PZR UNQ849/PRO1787 QLDHsGGHHSDKINKSEsVVyADIRKN______________
O95347 Y938 Sugiyama SMC2 CAPE SMC2L1 PRO0324 SKHKREAEDGAAKVSKMLKDyDWINAERHLFGQPNSAYDFK
O95573 Y591 Sugiyama ACSL3 ACS3 FACL3 LACS3 DGCLKIIDRKKDLVKLQAGEyVsLGKVEAALKNLPLVDNIC
O95757 Y30 Sugiyama HSPA4L APG1 HSPH3 OSP94 FLNCYIAVARsGGIETIANEySDRCtPACIsLGSRTRAIGN
O95757 Y627 Sugiyama HSPA4L APG1 HSPH3 OSP94 MIMQDKLEKERNDAKNAVEEyVyDFRDRLGtVYEKFITPED
O95757 Y629 Sugiyama HSPA4L APG1 HSPH3 OSP94 MQDKLEKERNDAKNAVEEyVyDFRDRLGtVYEKFITPEDLS
O95881 Y137 Sugiyama TXNDC12 TLP19 UNQ713/PRO1376 FLDPSGKVHPEIINENGNPsyKyFyVsAEQVVQGMKEAQER
O95926 Y210 Sugiyama SYF2 CBPIN GCIPIP IEKRDKYSRRRPYNDDADIDyINERNAKFNKKAERFYGKYT
O95997 Y111 Sugiyama PTTG1 EAP1 PTTG TUTR1 KKMTEKTVKAKSSVPASDDAyPEIEKFFPFNPLDFESFDLP
O96019 Y68 Sugiyama ACTL6A BAF53 BAF53A INO80K DDGsTLMEIDGDKGKQGGPtyyIDtNALRVPRENMEAIsPL
P00338 Y239 Sugiyama LDHA PIG19 GtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVADL
P00505 Y96 Sugiyama GOT2 KYAT4 VLPSVRKAEAQIAAKNLDKEyLPIGGLAEFCKASAELALGE
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P00558 Y196 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MVGVNLPQKAGGFLMKKELNyFAKALEsPERPFLAILGGAK
P00966 Y163 Sugiyama ASS1 ASS APWRMPEFYNRFKGRNDLMEyAKQHGIPIPVtPKNPWSMDE
P02786 Y168 Sugiyama TFRC NENsyVPREAGsQKDENLALyVENQFREFKLSKVWRDQHFV
P02786 Y402 Sugiyama TFRC KEIKILNIFGVIKGFVEPDHyVVVGAQRDAWGPGAAKSGVG
P04181 Y48 Sugiyama OAT VATKKtVQGPPtSDDIFEREyKyGAHNyHPLPVALERGKGI
P04181 Y50 Sugiyama OAT TKKtVQGPPtSDDIFEREyKyGAHNyHPLPVALERGKGIyL
P04181 Y55 Sugiyama OAT QGPPtSDDIFEREyKyGAHNyHPLPVALERGKGIyLWDVEG
P04406 Y314 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK
P04406 Y320 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____
P04406 Y94 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 ItIFQERDPsKIKWGDAGAEyVVEstGVFttMEKAGAHLQG
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05067 Y308 Sugiyama APP A4 AD1 REVCSEQAETGPCRAMISRWyFDVTEGKCAPFFyGGCGGNR
P05455 Y104 Sugiyama SSB EDKTKIRRsPsKPLPEVTDEyKNDVKNRsVYIKGFPtDAtL
P05787 Y204 Sugiyama KRT8 CYK8 NKRTEMENEFVLIKKDVDEAyMNKVELESRLEGLTDEINFL
P05997 S1308 Sugiyama COL5A2 SKKHPARTCDDLKLCHSAKQsGEyWIDPNQGSVEDAIKVYC
P05997 Y1311 Sugiyama COL5A2 HPARTCDDLKLCHSAKQsGEyWIDPNQGSVEDAIKVYCNME
P06733 Y189 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 MILPVGAANFREAMRIGAEVyHNLKNVIKEKyGKDAtNVGD
P06733 Y270 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV
P06733 Y280 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD
P06733 Y287 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 PsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKF
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07205 Y196 Sugiyama PGK2 PGKB MVGVNLPHKASGFLMKKELDyFAKALENPVRPFLAILGGAK
P07237 Y94 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK
P07237 Y99 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB LAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPKEytAG
P07355 Y147 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sLIEIICsRtNQELQEINRVyKEMYKtDLEKDIIsDtsGDF
P07355 Y188 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT
P07355 Y199 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RAEDGsVIDyELIDQDARDLyDAGVKRKGTDVPKWIsIMTE
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 Y36 Sugiyama TUBB TUBB5 OK/SW-cl.56 IGAKFWEVISDEHGIDPTGtyHGDsDLQLDRIsVyyNEAtG
P07437 Y50 Sugiyama TUBB TUBB5 OK/SW-cl.56 IDPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEP
P07437 Y51 Sugiyama TUBB TUBB5 OK/SW-cl.56 DPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPG
P07711 Y330 Sugiyama CTSL CTSL1 GyVKMAKDRRNHCGIAsAAsyPtV_________________
P07814 Y1504 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KPLCELQPGAKCVCGKNPAKyytLFGRsy____________
P07814 Y1505 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PLCELQPGAKCVCGKNPAKyytLFGRsy_____________
P07814 Y827 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK
P07858 Y244 Sugiyama CTSB CPSB HYGYNSYSVSNSEKDIMAEIyKNGPVEGAFSVYSDFLLYKS
P07900 Y197 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA GEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIGyP
P07900 Y284 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI
P07900 Y309 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF
P07900 Y313 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG
P07900 Y492 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLR
P07900 Y493 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLRK
P07900 Y61 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KEIFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLI
P08238 Y192 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIGyP
P08238 Y276 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI
P08238 Y301 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF
P08238 Y305 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG
P08238 Y472 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKE
P08238 Y484 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR
P08238 Y485 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVRK
P08238 Y56 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEIFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDII
P08238 Y619 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR
P08621 Y146 Sugiyama SNRNP70 RNPU1Z RPU1 SNRP70 U1AP1 yGPIKRIHMVYSKRsGKPRGyAFIEyEHERDMHSAYKHADG
P08708 Y84 Sugiyama RPS17 RPS17L GPVRGISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKE
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09234 Y8 Sugiyama SNRPC _____________MPKFyCDyCDtyLtHDsPsVRKTHCSGR
P09651 Y341 Sugiyama HNRNPA1 HNRPA1 QSSNFGPMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGss
P09651 Y347 Sugiyama HNRNPA1 HNRPA1 PMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGssssssyG
P0CG38 Y1062 Sugiyama POTEI GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG39 Y1025 Sugiyama POTEJ GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P10809 S225 Sugiyama HSPD1 HSP60 KtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVL
P10809 Y223 Sugiyama HSPD1 HSP60 DGKtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAy
P10809 Y227 Sugiyama HSPD1 HSP60 LNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLs
P10809 Y243 Sugiyama HSPD1 HSP60 yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI
P11047 Y352 Sugiyama LAMC1 LAMB2 tAEsASECLPCDCNGRsQECyFDPELyRSTGHGGHCTNCQD
P11142 S541 Sugiyama HSPA8 HSC70 HSP73 HSPA10 EAEKYKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGK
P11142 Y134 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FYPEEVSSMVLTKMKEIAEAyLGKtVTNAVVtVPAyFNDsQ
P11142 Y149 Sugiyama HSPA8 HSC70 HSP73 HSPA10 EIAEAyLGKtVTNAVVtVPAyFNDsQRQAtKDAGtIAGLNV
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11142 Y545 Sugiyama HSPA8 HSC70 HSP73 HSPA10 YKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKINDE
P11233 Y153 Sugiyama RALA RAL DKRQVsVEEAKNRAEQWNVNyVETSAKTRANVDKVFFDLMR
P11940 Y194 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF
P11940 Y291 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 ERQTELKRKFEQMKQDRITRyQGVNLyVKNLDDGIDDERLR
P11940 Y297 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KRKFEQMKQDRITRyQGVNLyVKNLDDGIDDERLRKEFsPF
P12270 Y140 Sugiyama TPR LEAEKRDLIRTNERLsQELEyLTEDVKRLNEKLKESNTTKG
P12277 Y125 Sugiyama CKB CKBB EHKTDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPH
P12814 Y215 Sugiyama ACTN1 KLRKDDPLTNLNTAFDVAEKyLDIPKMLDAEDIVGtARPDE
P12814 Y842 Sugiyama ACTN1 DTDTADQVMASFKILAGDKNyITMDELRRELPPDQAEyCIA
P12814 Y859 Sugiyama ACTN1 DKNyITMDELRRELPPDQAEyCIARMAPYTGPDSVPGALDY
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13639 Y373 Sugiyama EEF2 EF2 MITIHLPSPVTAQKyRCELLyEGPPDDEAAMGIKsCDPKGP
P13639 Y443 Sugiyama EEF2 EF2 TGLKVRIMGPNytPGKKEDLyLKPIQRTILMMGRYVEPIED
P13639 Y579 Sugiyama EEF2 EF2 KDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKH
P13639 Y639 Sugiyama EEF2 EF2 KGEVsARQELKQRARyLAEKyEWDVAEARKIWCFGPDGTGP
P13639 Y671 Sugiyama EEF2 EF2 CFGPDGTGPNILTDITKGVQyLNEIKDSVVAGFQWATKEGA
P13639 Y730 Sugiyama EEF2 EF2 HADAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQ
P13667 Y137 Sugiyama PDIA4 ERP70 ERP72 VAKIDAtsAsVLAsRFDVsGyPtIKILKKGQAVDyEGsRtQ
P13667 Y448 Sugiyama PDIA4 ERP70 ERP72 RAATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLs
P13667 Y458 Sugiyama PDIA4 ERP70 ERP72 VLEVAKDFPEytFAIADEEDyAGEVKDLGLsEsGEDVNAAI
P13674 Y141 Sugiyama P4HA1 P4HA FPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSF
P13674 Y282 Sugiyama P4HA1 P4HA ASDDQSDQKTTPKKKGVAVDyLPERQKyEMLCRGEGIKMTP
P13798 Y17 Sugiyama APEH D3F15S2 D3S48E DNF15S2 ____MERQVLLsEPEEAAALyRGLSRQPALsAACLGPEVtT
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P13987 Y86 Sugiyama CD59 MIC11 MIN1 MIN2 MIN3 MSK21 KFEHCNFNDVtTRLRENELtyyCCKKDLCNFNEQLENGGTS
P14314 Y106 Sugiyama PRKCSH G19P1 yIPSNRVNDGVCDCCDGtDEyNsGVICENtCKEKGRKEREs
P14618 Y148 Sugiyama PKM OIP3 PK2 PK3 PKM2 GtAEVELKKGATLKITLDNAyMEKCDENILWLDYKNICKVV
P14618 Y370 Sugiyama PKM OIP3 PK2 PK3 PKM2 NAVLDGADCIMLSGEtAKGDyPLEAVRMQHLIAREAEAAIy
P14625 Y258 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GNTLGRGTTITLVLKEEAsDyLELDTIKNLVKKYSQFINFP
P14625 Y429 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IKLYVRRVFITDDFHDMMPKyLNFVKGVVDsDDLPLNVsRE
P14625 Y527 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 AKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAGsSRK
P14649 Y86 Sugiyama MYL6B MLC1SA LEEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVL
P14854 Y34 Sugiyama COX6B1 COX6B TAPFDSRFPNQNQTRNCWQNyLDFHRCQKAMTAKGGDIsVC
P14854 Y57 Sugiyama COX6B1 COX6B FHRCQKAMTAKGGDIsVCEWyQRVYQsLCPtsWVTDWDEQR
P14927 Y90 Sugiyama UQCRB UQBP NLKHQILPKEQWTKyEEENFyLEPyLKEVIRERKEREEWAK
P15153 Y154 Sugiyama RAC2 LAPITYPQGLALAKEIDSVKyLECsALtQRGLKtVFDEAIR
P15259 Y92 Sugiyama PGAM2 PGAMM DGTDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQV
P15311 Y424 Sugiyama EZR VIL2 ERQAVDQIKsQEQLAAELAEytAKIALLEEARRRKEDEVEE
P15328 Y80 Sugiyama FOLR1 FOLR WRKNACCSTNTSQEAHKDVsyLyRFNWNHCGEMAPACKRHF
P15880 Y248 Sugiyama RPS2 RPS4 GCtAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQE
P15880 Y250 Sugiyama RPS2 RPS4 tAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQEFt
P17066 Y43 Sugiyama HSPA6 HSP70B' FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P17676 Y139 Sugiyama CEBPB TCF5 PP9092 SDLFSDDYGGKNCKKPAEyGyVsLGRLGAAKGALHPGCFAP
P17812 Y473 Sugiyama CTPS1 CTPS RRtLFQTKNsVMRKLyGDADyLEERHRHRFEVNPVWKKCLE
P17980 Y185 Sugiyama PSMC3 TBP1 PtEyDsRVKAMEVDERPtEQysDIGGLDKQIQELVEAIVLP
P17980 Y381 Sugiyama PSMC3 TBP1 ARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQCKAVCV
P17987 Y545 Sugiyama TCP1 CCT1 CCTA LRIDDLIKLHPESKDDKHGsyEDAVHsGALND_________
P18206 Y822 Sugiyama VCL KAVAGNIsDPGLQKsFLDsGyRILGAVAKVREAFQPQEPDF
P18615 Y170 Sugiyama NELFE RD RDBP GEEAEGPGAGDGPPRsFDWGyEERSGAHSsAsPPRsRSRDR
P18615 Y372 Sugiyama NELFE RD RDBP NsPKGCHRDKRTQIVysDDVyKENLVDGF____________
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18621 Y4 Sugiyama RPL17 _________________MVRysLDPENPtKsCKSRGSNLRV
P18669 S134 Sugiyama PGAM1 PGAMA CDABP0006 IWRRsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsCE
P18669 S137 Sugiyama PGAM1 PGAMA CDABP0006 RsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLK
P18669 Y119 Sugiyama PGAM1 PGAMA CDABP0006 NKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsKD
P18669 Y142 Sugiyama PGAM1 PGAMA CDABP0006 PPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIAR
P18669 Y92 Sugiyama PGAM1 PGAMA CDABP0006 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
P19105 Y142 Sugiyama MYL12A MLCB MRLC3 RLC LRELLttMGDRFtDEEVDELyREAPIDKKGNFNyIEFtRIL
P19105 Y155 Sugiyama MYL12A MLCB MRLC3 RLC DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
P19338 Y433 Sugiyama NCL FEDAAEIRLVSKDGKSKGIAyIEFKTEADAEKTFEEKQGtE
P19338 Y462 Sugiyama NCL AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs
P20042 Y174 Sugiyama EIF2S2 EIF2B DDGIsFsNQtGPAWAGSERDytyEELLNRVFNIMREKNPDM
P20618 Y150 Sugiyama PSMB1 PSC5 FPYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSAS
P21980 Y369 Sugiyama TGM2 PGYEGWQALDPTPQEKsEGtyCCGPVPVRAIKEGDLstKyD
P22059 Y456 Sugiyama OSBP OSBP1 MPVNFNEPLSMLQRLTEDLEyHELLDRAAKCENSLEQLCYV
P22059 Y791 Sugiyama OSBP OSBP1 WFERKKDPVTKELTHIyRGEyWECKEKQDWSsCPDIF____
P22234 Y22 Sugiyama PAICS ADE2 AIRC PAIS AtAEVLNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAG
P22314 Y55 Sugiyama UBA1 A1S9T UBE1 SVPTNGMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSV
P22314 Y560 Sugiyama UBA1 A1S9T UBE1 NPHIRVTSHQNRVGPDtERIyDDDFFQNLDGVANALDNVDA
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P22392 Y52 Sugiyama NME2 NM23B GFRLVAMKFLRAsEEHLKQHyIDLKDRPFFPGLVKYMNSGP
P22455 S573 Sugiyama FGFR4 JTK2 TKF AAKGNLREFLRARRPPGPDLsPDGPRSSEGPLSFPVLVSCA
P22455 Y602 Sugiyama FGFR4 JTK2 TKF GPLSFPVLVSCAYQVARGMQyLESRKCIHRDLAARNVLVTE
P22455 Y642 GPS6|SIGNOR|EPSD|Sugiyama FGFR4 JTK2 TKF EDNVMKIADFGLARGVHHIDyyKKTSNGRLPVKWMAPEALF
P22455 Y643 GPS6|SIGNOR|EPSD|Sugiyama FGFR4 JTK2 TKF DNVMKIADFGLARGVHHIDyyKKTSNGRLPVKWMAPEALFD
P22455 Y719 Sugiyama FGFR4 JTK2 TKF FSLLREGHRMDRPPHCPPELyGLMRECWHAAPSQRPTFKQL
P22455 Y754 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama FGFR4 JTK2 TKF PTFKQLVEALDKVLLAVSEEyLDLRLTFGPYSPSGGDASST
P22626 Y336 Sugiyama HNRNPA2B1 HNRPA2B1 MKsGNFGGsRNMGGPyGGGNyGPGGsGGsGGyGGRsRy___
P23246 Y488 Sugiyama SFPQ PSF PMYQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQV
P23246 Y490 Sugiyama SFPQ PSF YQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQVEK
P23526 Y165 Sugiyama AHCY SAHH QLLPGIRGIsEEtTTGVHNLyKMMANGILKVPAINVNDsVt
P23526 Y193 Sugiyama AHCY SAHH LKVPAINVNDsVtKsKFDNLyGCRESLIDGIKRATDVMIAG
P23528 Y140 Sugiyama CFL1 CFL SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs
P23528 Y68 Sugiyama CFL1 CFL ILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAt
P23528 Y82 Sugiyama CFL1 CFL QtVDDPyAtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFI
P23588 Y211 Sugiyama EIF4B DsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDRYDsD
P23588 Y609 Sugiyama EIF4B sASKyAALsVDGEDENEGEDyAE__________________
P24534 Y18 Sugiyama EEF1B2 EEF1B EF1B ___MGFGDLKsPAGLQVLNDyLADKSYIEGYVPsQADVAVF
P24752 Y214 Sugiyama ACAT1 ACAT MAT GsCAENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNE
P24752 Y90 Sugiyama ACAT1 ACAT MAT IAIQGAIEKAGIPKEEVKEAyMGNVLQGGEGQAPTRQAVLG
P25205 Y19 Sugiyama MCM3 __MAGtVVLDDVELREAQRDyLDFLDDEEDQGIyQsKVREL
P25205 Y32 Sugiyama MCM3 LREAQRDyLDFLDDEEDQGIyQsKVRELIsDNQyRLIVNVN
P25208 Y58 Sugiyama NFYB HAP3 SMNDHEDTNGSKESFREQDIyLPIANVARIMKNAIPQTGKI
P26196 Y469 Sugiyama DDX6 HLR2 RCK IEEQLGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP______
P26196 Y473 Sugiyama DDX6 HLR2 RCK LGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP__________
P26599 Y127 Sugiyama PTBP1 PTB ANTMVNYYTSVTPVLRGQPIyIQFsNHKELKtDSSPNQARA
P26639 Y53 Sugiyama TARS1 TARS KKNKEGsGDGGRAELNPWPEyIytRLEMYNILKAEHDsILA
P27348 Y149 Sugiyama YWHAQ LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG
P27348 Y48 Sugiyama YWHAQ AVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSIEQK
P27540 Y561 Sugiyama ARNT BHLHE2 PLEKSDGLFAQDRDPRFsEIyHNINADQSKGISSSTVPATQ
P27695 S129 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 QELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDE
P27695 Y128 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 LQELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGD
P27695 Y45 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 KSKTAAKKNDKEAAGEGPALyEDPPDQKtsPsGKPAtLKIC
P27816 Y47 Sugiyama MAP4 AtLEAEAFDDVVGETVGKTDyIPLLDVDEKtGNsESKKKPC
P27824 Y70 Sugiyama CANX TAPPSSPKVTYKAPVPtGEVyFADsFDRGTLSGWILSKAKK
P28062 Y184 Sugiyama PSMB8 LMP7 PSMB5i RING10 Y2 GMGLSMGSMICGWDKKGPGLyyVDEHGTRLSGNMFSTGSGN
P28062 Y185 Sugiyama PSMB8 LMP7 PSMB5i RING10 Y2 MGLSMGSMICGWDKKGPGLyyVDEHGTRLSGNMFSTGSGNT
P28062 Y271 Sugiyama PSMB8 LMP7 PSMB5i RING10 Y2 MKEDGWVKVEsTDVSDLLHQyREANQ_______________
P28066 Y185 Sugiyama PSMA5 CDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSLIILKQV
P28074 Y171 Sugiyama PSMB5 LMPX MB1 X GMGLSMGTMICGWDKRGPGLyyVDsEGNRISGATFSVGSGS
P28074 Y236 Sugiyama PSMB5 LMPX MB1 X RRAIyQATYRDAysGGAVNLyHVREDGWIRVSsDNVADLHE
P29144 Y1042 Sugiyama TPP2 TEALRDLKIQWMTKLDSsDIyNELKEtyPNyLPLyVARLHQ
P29353 Y427 Sugiyama SHC1 SHC SHCA RKQMPPPPPCPGRELFDDPsyVNVQNLDKARQAVGGAGPPN
P29401 Y481 Sugiyama TKT AANTKGICFIRTsRPENAIIyNNNEDFQVGQAKVVLKSKDD
P29692 Y26 Sugiyama EEF1D EF1D LAHEKIWFDKFKYDDAERRFyEQMNGPVAGAsRQENGAsVI
P30085 Y49 Sugiyama CMPK1 CMK CMPK UCK UMK UMPK ytHLSAGELLRDERKNPDsQyGELIEKYIKEGKIVPVEITI
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P30086 Y120 Sugiyama PEBP1 PBP PEBP GtVLsDyVGsGPPKGtGLHRyVWLVyEQDRPLKCDEPILsN
P30086 Y176 Sugiyama PEBP1 PBP PEBP KKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK_________
P30086 Y64 Sugiyama PEBP1 PBP PEBP tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW
P30101 Y115 Sugiyama PDIA3 ERP57 ERP60 GRP58 yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA
P30101 Y264 Sugiyama PDIA3 ERP57 ERP60 GRP58 CPHMTEDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVM
P30101 Y265 Sugiyama PDIA3 ERP57 ERP60 GRP58 PHMTEDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVMM
P30101 Y356 Sugiyama PDIA3 ERP57 ERP60 GRP58 FVMQEEFsRDGKALERFLQDyFDGNLKRyLKsEPIPESNDG
P30101 Y67 Sugiyama PDIA3 ERP57 ERP60 GRP58 LMLVEFFAPWCGHCKRLAPEyEAAAtRLKGIVPLAKVDCTA
P31153 Y235 Sugiyama MAT2A AMS2 MATA2 LDEMRDALKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGP
P31153 Y242 Sugiyama MAT2A AMS2 MATA2 LKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLt
P31327 Y1031 Sugiyama CPS1 VVVNCNPETVstDFDECDKLyFEELSLERILDIYHQEACGG
P31689 Y52 Sugiyama DNAJA1 DNAJ2 HDJ2 HSJ2 HSPF4 KYHPDKNPNEGEKFKQISQAyEVLSDAKKRELYDKGGEQAI
P31943 Y266 Sugiyama HNRNPH1 HNRPH HNRPH1 yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst
P31943 Y82 Sugiyama HNRNPH1 HNRPH HNRPH1 EsEDEVKLALKKDRETMGHRyVEVFKSNNVEMDWVLKHtGP
P31946 Y151 Sugiyama YWHAB LsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLG
P31946 Y21 Sugiyama YWHAB MTMDKsELVQKAKLAEQAERyDDMAAAMKAVtEQGHELsNE
P31946 Y213 Sugiyama YWHAB LAKTAFDEAIAELDtLNEEsyKDstLIMQLLRDNLtLWtSE
P31946 Y50 Sugiyama YWHAB AVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P31947 Y151 Sugiyama SFN HME1 LAEVATGDDKKRIIDSARsAyQEAMDISKKEMPPTNPIRLG
P31947 Y19 Sugiyama SFN HME1 __MERASLIQKAKLAEQAERyEDMAAFMKGAVEKGEELsCE
P31947 Y213 Sugiyama SFN HME1 LAKTtFDEAMADLHtLsEDsyKDstLIMQLLRDNLtLWTAD
P31947 Y48 Sugiyama SFN HME1 GAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsIEQK
P31948 Y354 Sugiyama STIP1 DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG
P31948 Y41 Sugiyama STIP1 DDALQCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDG
P32004 Y310 Sugiyama L1CAM CAML1 MIC5 YQNHNKTLQLLKVGEEDDGEyRCLAENSLGSARHAYYVTVE
P32119 Y115 Sugiyama PRDX2 NKEFB TDPX1 GLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFIIDGK
P32929 S61 Sugiyama CTH ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA
P32969 Y180 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 LIQQATTVKNKDIRKFLDGIyVsEKGtVQQADE________
P33121 Y693 Sugiyama ACSL1 FACL1 FACL2 LACS LACS1 LACS2 TMKAKRPELRNYFRSQIDDLyStIKV_______________
P33176 Y516 Sugiyama KIF5B KNS KNS1 EELAVNyDQKSQEVEDKTKEyELLSDELNQKsATLAsIDAE
P33316 Y227 Sugiyama DUT EKFEVKKGDRIAQLICERIFyPEIEEVQALDDtERGsGGFG
P33993 Y333 Sugiyama MCM7 CDC47 MCM2 EsGAGELtREELRQIAEEDFyEKLAASIAPEIYGHEDVKKA
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P34932 Y30 Sugiyama HSPA4 APG2 HSPH2 FQSCYVAVARAGGIETIANEysDRCtPACIsFGPKNRSIGA
P34932 Y597 Sugiyama HSPA4 APG2 HSPH2 VDLPIENQLLWQIDREMLNLyIENEGKMIMQDKLEKERNDA
P34932 Y624 Sugiyama HSPA4 APG2 HSPH2 MIMQDKLEKERNDAKNAVEEyVyEMRDKLSGEYEKFVSEDD
P35579 Y9 Sugiyama MYH9 ____________MAQQAADKyLyVDKNFINNPLAQADWAAK
P35580 Y13 Sugiyama MYH10 ________MAQRTGLEDPERyLFVDRAVIYNPATQADWTAK
P35606 Y824 Sugiyama COPB2 AFVVEEWVKETHADLWPAKQyPLVtPNEERNVMEEGKDFQP
P36871 Y157 Sugiyama PGM1 GPAPEAITDKIFQISKTIEEyAVCPDLKVDLGVLGKQQFDL
P36871 Y476 Sugiyama PGM1 GKQFSANDKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTD
P37802 Y192 Sugiyama TAGLN2 KIAA0120 CDABP0035 NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________
P38646 Y196 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 EtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNV
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P40261 Y11 Sugiyama NNMT __________MESGFTSKDTyLSHFNPRDYLEKYYKFGSRH
P40763 Y705 SIGNOR|EPSD STAT3 APRF KyCRPEsQEHPEADPGsAAPyLKTKFICVtPttCsNtIDLP
P41567 Y30 Sugiyama EIF1 SUI1 FDPFADAsKGDDLLPAGTEDyIHIRIQQRNGRKtLttVQGI
P42025 Y33 Sugiyama ACTR1B CTRN2 VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALE
P42025 Y38 Sugiyama ACTR1B CTRN2 SGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALEGDLFI
P42224 Y701 SIGNOR|iPTMNet|EPSD STAT1 YSRPKEAPEPMELDGPKGtGyIKtELIsVsEVHPSRLQttD
P42765 Y198 Sugiyama ACAA2 ECDKyALQSQQRWKAANDAGyFNDEMAPIEVKTKKGKQTMQ
P43243 S211 Sugiyama MATR3 KIAA0723 DRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDDRLRDGERCR
P43243 Y202 Sugiyama MATR3 KIAA0723 RHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDD
P43243 Y214 Sugiyama MATR3 KIAA0723 PsLNPVLDyDHGsRsQEsGyyDRMDyEDDRLRDGERCRDDs
P43490 Y34 Sugiyama NAMPT PBEF PBEF1 ATDSYKVTHYKQYPPNTSKVysyFECREKKTENSKLRKVKY
P46777 Y207 Sugiyama RPL5 MSTP030 sKEFNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyI
P46777 Y210 Sugiyama RPL5 MSTP030 FNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyIKNs
P46777 Y219 Sugiyama RPL5 MSTP030 IMGQNVADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEM
P46777 Y240 Sugiyama RPL5 MSTP030 KKQFsQyIKNsVtPDMMEEMyKKAHAAIRENPVyEKKPKKE
P46778 T29 Sugiyama RPL21 RGTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQ
P46778 Y156 Sugiyama RPL21 REAHFVRTNGKEPELLEPIPyEFMA________________
P47756 Y59 Sugiyama CAPZB LLSSVDQPLKIARDKVVGKDyLLCDyNRDGDSyRsPWSNKy
P47813 Y35 Sugiyama EIF1AX EIF1A EIF4C GKNENESEKRELVFKEDGQEyAQVIKMLGNGRLEAMCFDGV
P47897 Y748 Sugiyama QARS1 QARS VDCSVALAKPFDKFQFERLGyFsVDPDsHQGKLVFNRTVTL
P48643 Y274 Sugiyama CCT5 CCTE KIAA0098 PFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQQIKE
P48741 Y43 Sugiyama HSPA7 HSP70B FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P49207 Y32 Sugiyama RPL34 sYNtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGR
P49207 Y34 Sugiyama RPL34 NtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGRLR
P49321 Y540 Sugiyama NASP DMLDLAKIIFKRQETKEAQLyAAQAHLKLGEVSVESENYVQ
P49327 Y2462 Sugiyama FASN FAS NVMLLRAKtGGAyGEDLGADyNLsQVCDGKVsVHVIEGDHR
P49327 Y289 Sugiyama FASN FAS QEQLIRSLyQsAGVAPEsFEyIEAHGtGTKVGDPQELNGIt
P49327 Y45 Sugiyama FASN FAS NLIGGVDMVTDDDRRWKAGLyGLPRRsGKLKDLSRFDAsFF
P49458 Y18 Sugiyama SRP9 ___MPQYQTWEEFSRAAEKLyLADPMKARVVLKYRHsDGNL
P49588 Y667 Sugiyama AARS1 AARS QQIKKAEEIANEMIEAAKAVyTQDCPLAAAKAIQGLRAVFD
P49736 Y234 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 VFKERIsDMCKENREsLVVNyEDLAAREHVLAYFLPEAPAE
P50402 Y94 Sugiyama EMD EDMD STA yDLPKKEDALLyQsKGyNDDyyEEsyFTTRTyGEPEsAGPS
P50402 Y99 Sugiyama EMD EDMD STA KEDALLyQsKGyNDDyyEEsyFTTRTyGEPEsAGPSRAVRQ
P50897 Y264 Sugiyama PPT1 CLN1 PPT FGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLVFLA
P50990 Y30 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 GFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTTRTAYGPN
P50991 Y269 Sugiyama CCT4 CCTD SRB IQFCLSAPKTDMDNQIVVSDyAQMDRVLREERAYILNLVKQ
P50995 Y482 Sugiyama ANXA11 ANX11 sEtDLLDIRSEYKRMYGKsLyHDISGDtsGDyRKILLKICG
P50995 Y493 Sugiyama ANXA11 ANX11 YKRMYGKsLyHDISGDtsGDyRKILLKICGGND________
P51116 Y614 Sugiyama FXR2 FMR1L2 RGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLERTKPs
P51151 Y148 Sugiyama RAB9A RAB9 ISERQVsTEEAQAWCRDNGDyPyFETSAKDATNVAAAFEEA
P51965 Y77 Sugiyama UBE2E1 UBCH6 ADITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
P52298 Y14 Sugiyama NCBP2 CBP20 PIG55 _______MSGGLLKALRsDsyVELSQYRDQHFRGDNEEQEK
P52565 Y144 Sugiyama ARHGDIA GDIA1 SGMKYIQHTyRKGVKIDKtDyMVGsYGPRAEEyEFLtPVEE
P52565 Y156 Sugiyama ARHGDIA GDIA1 GVKIDKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYs
P52597 Y82 Sugiyama HNRNPF HNRPF GsEDDVKMALKKDRESMGHRyIEVFKSHRTEMDWVLKHsGP
P52888 Y576 Sugiyama THOP1 VLAKVDQALHTQTDADPAEEyARLCQEILGVPATPGTNMPA
P53634 Y438 Sugiyama CTSC CPPI SGMDYWIVKNsWGtGWGENGyFRIRRGtDECAIEsIAVAAt
P54577 Y292 Sugiyama YARS1 YARS KSEFVILRDEKWGGNKTytAyVDLEKDFAAEVVHPGDLKNS
P54577 Y388 Sugiyama YARS1 YARS LDIRVGKIITVEKHPDADsLyVEKIDVGEAEPRTVVSGLVQ
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55060 Y369 Sugiyama CSE1L CAS XPO2 VPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAACDL
P55196 Y1230 Sugiyama AFDN AF6 MLLT4 QtPPPRPEAyPIPtQtYtREyFtFPAsKsQDRMAPPQNQWP
P55209 Y106 Sugiyama NAP1L1 NRP VKCAQIEAKFyEEVHDLERKyAVLyQPLFDKRFEIINAIYE
P55209 Y110 Sugiyama NAP1L1 NRP QIEAKFyEEVHDLERKyAVLyQPLFDKRFEIINAIYEPTEE
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P55263 Y129 Sugiyama ADK IDKFGEILKRKAAEAHVDAHyyEQNEQPTGTCAACITGDNR
P55795 Y266 Sugiyama HNRNPH2 FTP3 HNRPH2 YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst
P55795 Y82 Sugiyama HNRNPH2 FTP3 HNRPH2 EsEEEVKLALKKDRETMGHRyVEVFKSNsVEMDWVLKHtGP
P55809 Y43 Sugiyama OXCT1 OXCT SCOT TWYKGCVCSFSTSAHRHTKFyTDPVEAVKDIPDGATVLVGG
P55884 Y768 Sugiyama EIF3B EIF3S9 ERRRTMMEDFRKYRKMAQELyMEQKNERLELRGGVDTDELD
P57053 Y38 Sugiyama H2BC12L H2BFS H2BS1 AVTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssK
P57053 Y41 Sugiyama H2BC12L H2BFS H2BS1 KAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
P57053 Y43 Sugiyama H2BC12L H2BFS H2BS1 QKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P58876 Y38 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
P58876 Y41 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
P58876 Y43 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P60174 Y209 Sugiyama TPI1 TPI LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG
P60174 Y48 Sugiyama TPI1 TPI tLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQNCy
P60660 Y29 Sugiyama MYL6 TAEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVL
P60660 Y86 Sugiyama MYL6 DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG
P60660 Y89 Sugiyama MYL6 HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI
P60709 Y198 Sugiyama ACTB LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y362 Sugiyama ACTB GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P60763 Y154 Sugiyama RAC3 LAPITYPQGLAMAREIGSVKyLECsALtQRGLKtVFDEAIR
P60842 Y197 Sugiyama EIF4A1 DDX2A EIF4A KMFVLDEADEMLsRGFKDQIyDIFQKLNsNtQVVLLSATMP
P60842 Y70 Sugiyama EIF4A1 DDX2A EIF4A yGFEKPsAIQQRAILPCIKGyDVIAQAQsGtGKTATFAISI
P61024 S9 Sugiyama CKS1B CKS1 PNAS-143 PNAS-16 ____________MSHKQIyysDKyDDEEFEyRHVMLPKDIA
P61024 Y19 Sugiyama CKS1B CKS1 PNAS-143 PNAS-16 __MSHKQIyysDKyDDEEFEyRHVMLPKDIAKLVPKTHLMs
P61024 Y7 Sugiyama CKS1B CKS1 PNAS-143 PNAS-16 ______________MSHKQIyysDKyDDEEFEyRHVMLPKD
P61081 Y172 Sugiyama UBE2M UBC12 VLQNNRRLFEQNVQRSMRGGyIGstyFERCLK_________
P61081 Y177 Sugiyama UBE2M UBC12 RRLFEQNVQRSMRGGyIGstyFERCLK______________
P61163 Y33 Sugiyama ACTR1A CTRN1 VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALE
P61163 Y38 Sugiyama ACTR1A CTRN1 SGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALEGDIFI
P61247 Y256 Sugiyama RPS3A FTE1 MFTL sssGKAtGDEtGAKVERADGyEPPVQEsV____________
P61313 Y6 Sugiyama RPL15 EC45 TCBAP0781 _______________MGAYKyIQELWRKKQSDVMRFLLRVR
P61353 Y85 Sugiyama RPL27 RSKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPA
P61604 Y88 Sugiyama HSPE1 GDKVLLPEyGGtKVVLDDKDyFLFRDGDILGKyVD______
P61978 Y72 Sugiyama HNRNPK HNRPK KNAGAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISA
P61981 S215 Sugiyama YWHAG HLAKtAFDDAIAELDtLNEDsyKDstLIMQLLRDNLtLWts
P61981 Y20 Sugiyama YWHAG _MVDREQLVQKARLAEQAERyDDMAAAMKNVtELNEPLsNE
P61981 Y216 Sugiyama YWHAG LAKtAFDDAIAELDtLNEDsyKDstLIMQLLRDNLtLWtsD
P61981 Y49 Sugiyama YWHAG NVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P62081 Y177 Sugiyama RPS7 HLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEFQL___
P62241 Y113 Sugiyama RPS8 OK/SW-cl.83 TKTLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEE
P62241 Y117 Sugiyama RPS8 OK/SW-cl.83 VKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEEIL
P62258 Y131 Sugiyama YWHAE AANtGEsKVFyyKMKGDYHRyLAEFAtGNDRKEAAENsLVA
P62258 Y152 Sugiyama YWHAE LAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLG
P62258 Y214 Sugiyama YWHAE LAKAAFDDAIAELDtLsEEsyKDstLIMQLLRDNLtLWtsD
P62258 Y49 Sugiyama YWHAE KVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssIEQK
P62263 S70 Sugiyama RPS14 PRO2640 KETICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELGI
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62269 Y95 Sugiyama RPS18 D6S218E RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 Y18 Sugiyama RPS13 ___MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVKEQIy
P62280 Y55 Sugiyama RPS11 RYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILsG
P62333 Y328 Sugiyama PSMC6 SUG2 ARLDILKIHAGPITKHGEIDyEAIVKLSDGFNGADLRNVCT
P62714 Y80 Sugiyama PPP2CB GQFHDLMELFRIGGKsPDtNyLFMGDyVDRGYYSVETVTLL
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62750 Y144 Sugiyama RPL23A VNtLIRPDGEKKAYVRLAPDyDALDVANKIGII________
P62750 Y74 Sugiyama RPL23A LRRQPKYPRKSAPRRNKLDHyAIIKFPLTTEsAMKKIEDNN
P62807 Y38 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI AVTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssK
P62807 Y41 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI KAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMG
P62807 Y43 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI QKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMGIM
P62826 Y146 Sugiyama RAN ARA24 OK/SW-cl.81 IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR
P62826 Y147 Sugiyama RAN ARA24 OK/SW-cl.81 KDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARK
P62906 Y11 Sugiyama RPL10A NEDD6 __________MSSKVsRDtLyEAVREVLHGNQRKRRKFLET
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 Y79 Sugiyama PPIA CYPA GFMCQGGDFtRHNGTGGKsIyGEKFEDENFILKHtGPGILs
P62979 T147 Sugiyama RPS27A UBA80 UBCEP1 GAGVFMAsHFDRHyCGKCCLtyCFNKPEDK___________
P62979 Y148 Sugiyama RPS27A UBA80 UBCEP1 AGVFMAsHFDRHyCGKCCLtyCFNKPEDK____________
P63000 Y154 Sugiyama RAC1 TC25 MIG5 LTPITYPQGLAMAKEIGAVKyLECsALtQRGLKtVFDEAIR
P63104 Y149 Sugiyama YWHAZ LAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLG
P63104 Y211 Sugiyama YWHAZ LAKtAFDEAIAELDtLsEEsyKDstLIMQLLRDNLtLWtsD
P63104 Y48 Sugiyama YWHAZ sVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssIEQK
P63220 Y53 Sugiyama RPS21 QMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRLA
P63261 Y198 Sugiyama ACTG1 ACTG LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y362 Sugiyama ACTG1 ACTG GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67775 Y80 Sugiyama PPP2CA GQFHDLMELFRIGGKsPDtNyLFMGDyVDRGYYSVETVTLL
P67809 Y72 Sugiyama YBX1 NSEP1 YB1 KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68104 Y29 Sugiyama EEF1A1 EEF1A EF1A LENG7 NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
P68104 Y86 Sugiyama EEF1A1 EEF1A EF1A LENG7 ERERGITIDISLWKFEtsKyyVtIIDAPGHRDFIKNMITGT
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 Y432 Sugiyama TUBA1B GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
P98082 Y38 Sugiyama DAB2 DOC2 AAPKAPsKKEKKKGPEKTDEyLLARFKGDGVKYKAKLIGID
Q00059 Y165 Sugiyama TFAM TCF6 TCF6L2 KKKELTLLGKPKRPRsAYNVyVAERFQEAKGDsPQEKLKTV
Q00169 Y140 Sugiyama PITPNA PITPN GTQENVHKLEPEAWKHVEAVyIDIADRSQVLSKDYKAEEDP
Q00534 Y13 Sugiyama CDK6 CDKN6 ________MEKDGLCRADQQyECVAEIGEGAyGKVFKARDL
Q00610 S1483 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 VNEsLNNLFITEEDyQALRTsIDAyDNFDNIsLAQRLEKHE
Q00610 Y899 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 LAKIyIDsNNNPERFLRENPyyDsRVVGKYCEKRDPHLACV
Q00653 Y247 Sugiyama NFKB2 LYT10 NLKISRMDKTAGSVRGGDEVyLLCDKVQKDDIEVRFYEDDE
Q00839 Y257 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 QKGGDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVE
Q00839 Y260 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED
Q01105 Y146 Sugiyama SET tEFEDIKsGyRIDFyFDENPyFENKVLSKEFHLNEsGDPss
Q02878 T118 Sugiyama RPL6 TXREB1 GDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQHVR
Q02878 Y115 Sugiyama RPL6 TXREB1 PVGGDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQ
Q02878 Y116 Sugiyama RPL6 TXREB1 VGGDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQH
Q04760 Y136 SIGNOR|PSP GLO1 HNGNsDPRGFGHIGIAVPDVySACKRFEELGVKFVKKPDDG
Q04837 Y73 Sugiyama SSBP1 SSBP PVTIFSLATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPG
Q04917 Y154 Sugiyama YWHAH YWHA1 LAEVASGEKKNsVVEAsEAAyKEAFEISKEQMQPTHPIRLG
Q04917 Y20 Sugiyama YWHAH YWHA1 _MGDREQLLQRARLAEQAERyDDMAsAMKAVtELNEPLsNE
Q04917 Y49 Sugiyama YWHAH YWHA1 AVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSIEQK
Q05639 Y29 Sugiyama EEF1A2 EEF1AL STN NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
Q06830 Y116 Sugiyama PRDX1 PAGA PAGB TDPX2 GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK
Q07157 Y1191 Sugiyama TJP1 ZO1 LRPEAQPHPsAGPKPAEsKQyFEQysRsyEQVPPQGFTSRA
Q07666 Y145 Sugiyama KHDRBS1 SAM68 LtAEIEKIQKGDSKKDDEENyLDLFsHKNMKLKERVLIPVK
Q07960 Y65 Sugiyama ARHGAP1 CDC42GAP RHOGAP1 DDsKsssPELVtHLKWDDPyyDIARHQIVEVAGDDKYGRKI
Q08043 Y229 Sugiyama ACTN3 KLRKDDPIGNLNTAFEVAEKyLDIPKMLDAEDIVNtPKPDE
Q08211 Y68 Sugiyama DHX9 DDX9 LKP NDH2 MGNSTNKKDAQSNAARDFVNyLVRINEIKsEEVPAFGVAsP
Q08J23 Y52 Sugiyama NSUN2 SAKI TRM4 AGWEGGyPEIVKENKLFEHyyQELKIVPEGEWGQFMDALRE
Q12931 Y513 Sugiyama TRAP1 HSP75 HSPC5 GtRNIyyLCAPNRHLAEHsPyyEAMKKKDTEVLFCFEQFDE
Q12931 Y514 Sugiyama TRAP1 HSP75 HSPC5 tRNIyyLCAPNRHLAEHsPyyEAMKKKDTEVLFCFEQFDEL
Q13043 Y433 GPS6|PSP STK4 KRS2 MST1 KsVPGPLKNSsDWKIPQDGDyEFLKsWtVEDLQKRLLALDP
Q13085 Y2144 Sugiyama ACACA ACAC ACC1 ACCA VEIKFRRKDLVKTMRRVDPVyIHLAERLGTPELSTAERKEL
Q13098 Y172 Sugiyama GPS1 COPS1 CSN1 YKGNSIKESIRRGHDDLGDHyLDCGDLSNALKCYSRARDYC
Q13228 Y28 Sugiyama SELENBP1 SBP CGPGySTPLEAMKGPREEIVyLPCIyRNtGtEAPDyLATVD
Q13228 Y33 Sugiyama SELENBP1 SBP STPLEAMKGPREEIVyLPCIyRNtGtEAPDyLATVDVDPKs
Q13263 Y133 Sugiyama TRIM28 KAP1 RNF96 TIF1B TVVDCPVCKQQCFSKDIVENyFMRDsGsKAATDAQDANQCC
Q13263 Y242 Sugiyama TRIM28 KAP1 RNF96 TIF1B ESCDTLTCRDCQLNAHKDHQyQFLEDAVRNQRKLLAsLVKR
Q13263 Y517 Sugiyama TRIM28 KAP1 RNF96 TIF1B LtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATGQPGtA
Q13283 T21 Sugiyama G3BP1 G3BP MVMEKPsPLLVGREFVRQyytLLNQAPDMLHRFYGKNssyV
Q13283 Y20 Sugiyama G3BP1 G3BP _MVMEKPsPLLVGREFVRQyytLLNQAPDMLHRFYGKNssy
Q13303 Y270 Sugiyama KCNAB2 KCNA2B KCNK2 IVSGKYDSGIPPYSRAsLKGyQWLKDKILSEEGRRQQAKLK
Q13310 Y194 Sugiyama PABPC4 APP1 PABP4 KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF
Q13405 Y45 Sugiyama MRPL49 C11orf4 NOF1 OK/SW-cl.67 LLSQTQGPPDYPRFVEsVDEyQFVERLLPATRIPDPPKHEH
Q13435 Y591 Sugiyama SF3B2 SAP145 LHDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSD
Q13435 Y592 Sugiyama SF3B2 SAP145 HDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSDE
Q13442 S19 Sugiyama PDAP1 HASPP28 __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE
Q13442 Y17 Sugiyama PDAP1 HASPP28 ____MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREE
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13546 Y384 Sugiyama RIPK1 RIP RIP1 EHPQEENEPSLQSKLQDEANyHLyGsRMDRQTKQQPRQNVA
Q13561 Y6 Sugiyama DCTN2 DCTN50 _______________MADPKyADLPGIARNEPDVYETSDLP
Q13561 Y86 Sugiyama DCTN2 DCTN50 GLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKYQRL
Q13573 Y292 Sugiyama SNW1 SKIIP SKIP GRGLQTVHINENFAKLAEALyIADRKAREAVEMRAQVERKM
Q13615 Y1023 Sugiyama MTMR3 KIAA0371 ZFYVE10 ATssPDQPSRSHLDDDGMSVyTDTIQQRLRQIESGHQQEVE
Q13642 Y117 Sugiyama FHL1 SLIM1 DsPKCKGCFKAIVAGDQNVEyKGtVWHKDCFTCSNCKQVIG
Q13765 Y120 Sugiyama NACA HSD48 KNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAAA
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q14240 Y71 Sugiyama EIF4A2 DDX2B EIF4F yGFEKPsAIQQRAIIPCIKGyDVIAQAQsGtGKTATFAISI
Q14247 Y446 Sugiyama CTTN EMS1 sFKAELsyRGPVsGtEPEPVysMEAADyREASSQQGLAYAT
Q14257 Y311 Sugiyama RCN2 ERC55 NPDLFLtsEAtDyGRQLHDDyFyHDEL______________
Q14257 Y313 Sugiyama RCN2 ERC55 DLFLtsEAtDyGRQLHDDyFyHDEL________________
Q14257 Y54 Sugiyama RCN2 ERC55 ERRsDyDREALLGVQEDVDEyVKLGHEEQQKRLQAIIKKID
Q14258 Y245 Sugiyama TRIM25 EFP RNF147 ZNF147 NRQQDVRMTANRKVEQLQQEytEMKALLDASETTSTRKIKE
Q14568 Y283 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI
Q14651 Y463 Sugiyama PLS1 VNKPPYPALGGNMKKIENCNyAVELGKNKAKFSLVGIAGQD
Q14671 Y83 Sugiyama PUM1 KIAA0099 PUMH1 SPVPGSIGVAGRsQDDAMVDyFFQRQHGEQLGGGGsGGGGy
Q14696 Y58 Sugiyama MESD KIAA0081 MESDC2 MESDM UNQ1911/PRO4369 PGTPDESTPPPRKKKKDIRDyNDADMARLLEQWEKDDDIEE
Q14974 Y529 Sugiyama KPNB1 NTF97 KLLETTDRPDGHQNNLRSSAyEsLMEIVKNSAKDCYPAVQK
Q15024 Y13 Sugiyama EXOSC7 KIAA0116 RRP42 ________MASVTLSEAEKVyIVHGVQEDLRVDGRGCEDYR
Q15056 Y86 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 sIRsVRLVRDKDTDKFKGFCyVEFDEVDsLKEALtyDGALL
Q15181 Y169 Sugiyama PPA1 IOPPP PP EGETDWKVIAINVDDPDAANyNDINDVKRLKPGYLEATVDW
Q15181 Y17 Sugiyama PPA1 IOPPP PP ____MSGFSTEERAAPFsLEyRVFLKNEKGQyIsPFHDIPI
Q15293 Y278 Sugiyama RCN1 RCN LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE
Q15369 Y18 Sugiyama ELOC TCEB1 ___MDGEEKtyGGCEGPDAMyVKLISSDGHEFIVKREHALt
Q15369 Y8 Sugiyama ELOC TCEB1 _____________MDGEEKtyGGCEGPDAMyVKLISSDGHE
Q15424 Y723 Sugiyama SAFB HAP HET SAFB1 EQERRPAVRRPYDLDRRDDAyWPEAKRAALDERYHSDFNRQ
Q15427 T14 Sugiyama SF3B4 SAP49 _______MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFL
Q15427 Y16 Sugiyama SF3B4 SAP49 _____MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFLQA
Q15459 Y456 Sugiyama SF3A1 SAP114 PRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAERRtDI
Q15527 Y123 Sugiyama SURF2 GRRYQRALCKYEECQKQGVEyVPACLVHRRRRREDQMDGDG
Q15650 Y289 Sugiyama TRIP4 RQT4 LLEFDRtsIRRtQVIDDESDyFASDSNQWLSKLERETLQKR
Q15785 Y25 Sugiyama TOMM34 URCC3 FPDsVEELRAAGNESFRNGQyAEASALyGRALRVLQAQGss
Q16719 Y441 Sugiyama KYNU RGVVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsA
Q16719 Y448 Sugiyama KYNU RNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAETKN___
Q16719 Y47 Sugiyama KYNU ERVALHLDEEDKLRHFRECFyIPKIQDLPPVDLSLVNKDEN
Q16719 Y86 Sugiyama KYNU ENAIYFLGNSLGLQPKMVKtyLEEELDKWAKIAAYGHEVGK
Q4VXU2 Y291 Sugiyama PABPC1L C20orf119 ERQNELKRRFEQMKQDRLRRyQGVNLyVKNLDDSIDDDKLR
Q4VXU2 Y297 Sugiyama PABPC1L C20orf119 KRRFEQMKQDRLRRyQGVNLyVKNLDDSIDDDKLRKEFSPY
Q53H82 Y121 Sugiyama LACTB2 CGI-83 IKKLPRNPQREEIIGNGEQQyVyLKDGDVIKTEGATLRVLY
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF6 Y167 Sugiyama HSP90AB4P GEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIGCL
Q58FF6 Y32 Sugiyama HSP90AB4P KEIFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDII
Q58FF7 Y171 Sugiyama HSP90AB3P HSP90BC GEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIGyP
Q58FF7 Y492 Sugiyama HSP90AB3P HSP90BC TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR
Q58FF7 Y56 Sugiyama HSP90AB3P HSP90BC EEIFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FF8 Y198 Sugiyama HSP90AB2P HSP90BB DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI
Q58FF8 Y260 Sugiyama HSP90AB2P HSP90BB VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW
Q58FF8 Y261 Sugiyama HSP90AB2P HSP90BB RYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVWK
Q58FF8 Y56 Sugiyama HSP90AB2P HSP90BB KEIFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FG0 Y177 Sugiyama HSP90AA5P HSP90AE GQLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQ
Q58FG0 Y178 Sugiyama HSP90AA5P HSP90AE QLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQK
Q5JTH9 Y1251 Sugiyama RRP12 KIAA0690 AEYKAKKAKGDVKKKGRPDPyAyIPLNRSKLNRRKKMKLQG
Q5JTH9 Y1253 Sugiyama RRP12 KIAA0690 YKAKKAKGDVKKKGRPDPyAyIPLNRSKLNRRKKMKLQGQF
Q5QNW6 Y38 Sugiyama H2BC18 HIST2H2BF AVTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q5QNW6 Y41 Sugiyama H2BC18 HIST2H2BF KVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q5QNW6 Y43 Sugiyama H2BC18 HIST2H2BF QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q5VTE0 Y29 Sugiyama EEF1A1P5 EEF1AL3 NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
Q5VTE0 Y86 Sugiyama EEF1A1P5 EEF1AL3 ERERGITIDISLWKFEtsKyyVtIIDAPGHRDFIKNMITGT
Q5VV41 Y216 Sugiyama ARHGEF16 EPHEXIN4 NBR KKTLGRKRGHKGsFKDDPQLyQEIQERGLNtsQEsDDDILD
Q6PKG0 Y633 Sugiyama LARP1 KIAA0731 LARP MEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVtQtPHyM
Q6S8J3 Y1062 Sugiyama POTEE A26C1A POTE2 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q71U36 Y432 Sugiyama TUBA1A TUBA3 GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
Q7KZF4 Y476 Sugiyama SND1 TDRD11 SKGLATVIRYRQDDDQRssHyDELLAAEARAIKNGKGLHSK
Q86UK7 Y306 Sugiyama ZNF598 QFSYAPRHSRRNEGVVGGEDyEEVDRysRQGRVARAGTRGA
Q8N0Y7 S134 Sugiyama PGAM4 PGAM3 IWRRsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSYE
Q8N0Y7 S137 Sugiyama PGAM4 PGAM3 RsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSYESPK
Q8N0Y7 Y119 Sugiyama PGAM4 PGAM3 NKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsKD
Q8N0Y7 Y92 Sugiyama PGAM4 PGAM3 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
Q8N7H5 Y322 Sugiyama PAF1 PD2 KASKGyEENyFFIFREGDGVyyNELETRVRLSKRRAKAGVQ
Q8NBS9 Y251 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 ALGLEHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDG
Q8NBS9 Y289 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 RDGKKVDQYKGKRDLEsLREyVEsQLQRTETGATETVTPSE
Q8NDI1 Y585 Sugiyama EHBP1 KIAA0903 NACSIN TYKVGNYETDTNssVDQEKFyAELSDLKREPELQQPISGAV
Q8NI22 Y135 Sugiyama MCFD2 SDNSF DELINIIDGVLRDDDKNNDGyIDyAEFAKSLQ_________
Q8NI22 Y138 Sugiyama MCFD2 SDNSF INIIDGVLRDDDKNNDGyIDyAEFAKSLQ____________
Q8TD19 Y52 Sugiyama NEK9 KIAA1995 NEK8 NERCC PSASQGPRAGGGAAEQEELHyIPIRVLGRGAFGEAtLyRRT
Q8TEW0 Y1080 Sugiyama PARD3 PAR3 PAR3A QERIQAKTREFRERQARERDyAEIQDFHRTFGCDDELMYGG
Q8TEW0 Y388 Sugiyama PARD3 PAR3 PAR3A QLSQSEKNNyyssRFsPDsQyIDNRSVNSAGLHTVQRAPRL
Q8WUA2 Y401 Sugiyama PPIL4 TSKKHKKKTHHCsEEKEDEDyMPIKNTNQDIYREMGFGHYE
Q8WWM7 S276 Sugiyama ATXN2L A2D A2LG A2LP A2RP MFKFNEENyGVKTtyDssLssytVPLEKDNsEEFRQRELRA
Q8WWM7 Y270 Sugiyama ATXN2L A2D A2LG A2LP A2RP GWDPNEMFKFNEENyGVKTtyDssLssytVPLEKDNsEEFR
Q8WYP5 Y1790 Sugiyama AHCTF1 ELYS TMBS62 MSTP108 QSVRKKTRKAKEISEASENIySDVRGLsQNQQIPQNsVtPR
Q93079 Y38 Sugiyama H2BC9 H2BFJ HIST1H2BH AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q93079 Y41 Sugiyama H2BC9 H2BFJ HIST1H2BH KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q93079 Y43 Sugiyama H2BC9 H2BFJ HIST1H2BH QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q969T4 Y91 Sugiyama UBE2E3 UBCE4 UBCH9 AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
Q96C19 T84 Sugiyama EFHD2 SWS1 DLNQGIGEPQsPsRRVFNPytEFKEFSRKQIKDMEKMFKQy
Q96C90 Y29 Sugiyama PPP1R14B PLCB3N PNG GAALAAPAPGPGsGGPGPRVyFQsPPGAAGEGPGGADDEGP
Q96CT7 Y38 Sugiyama CCDC124 RRAEAKAAADAKKQKELEDAyWKDDDKHVMRKEQRKEEKEK
Q96EU6 Y138 Sugiyama RRP36 C6orf153 HSPC253 RDPRFDDLSGEYNPEVFDKtyQFLNDIRAKEKELVKKQLKK
Q96F86 Y258 Sugiyama EDC3 LSM16 YJDC YJEFN2 PP844 NERPTRYRHDENILESEPIVyRRIIVPHNVSKEFCTDSGLV
Q96GX9 Y57 Sugiyama APIP CGI-29 HLGWVTGTGGGISLKHGDEIyIAPsGVQKERIQPEDMFVCD
Q96HE7 Y178 Sugiyama ERO1A ERO1L UNQ434/PRO865 HDDSSDNFCEADDIQsPEAEyVDLLLNPERYTGYKGPDAWK
Q96LR5 Y85 Sugiyama UBE2E2 UBCH8 AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
Q96P70 Y889 Sugiyama IPO9 IMP9 KIAA1192 RANBP9 HSPC273 HGINADDKRLQDIRVKGEEIysMDEGIRTRSKSAKNPERWT
Q96QK1 Y507 Sugiyama VPS35 MEM3 TCCCTA00141 EQSLVGRFIHLLRsEDPDQQyLILNTARKHFGAGGNQRIRF
Q99459 Y511 Sugiyama CDC5L KIAA0432 PCDC5RP EIVLPENAEKELEEREIDDtyIEDAADVDARKQAIRDAERV
Q99470 Y187 Sugiyama SDF2 GRPISGQKEVHGMAQPSQNNyWKAMEGIFMKPSELLKAEAH
Q99536 Y240 Sugiyama VAT1 TASASKHEALKENGVTHPIDyHttDyVDEIKKISPKGVDIV
Q99536 Y245 Sugiyama VAT1 KHEALKENGVTHPIDyHttDyVDEIKKISPKGVDIVMDPLG
Q99543 Y137 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 KHHPDKRKAAGEPIKEGDNDyFTCITKAYEMLSDPVKRRAF
Q99613 Y881 Sugiyama EIF3C EIF3S8 EKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMRR
Q99733 Y95 Sugiyama NAP1L4 NAP2 VRCAHIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVE
Q99733 Y99 Sugiyama NAP1L4 NAP2 HIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVEPtDA
Q99798 Y432 Sugiyama ACO2 SQFtITPGSEQIRAtIERDGyAQILRDLGGIVLANACGPCI
Q99832 Y302 Sugiyama CCT7 CCTH NIP7-1 HHSGAKVVLSKLPIGDVAtQyFADRDMFCAGRVPEEDLKRT
Q99877 Y38 Sugiyama H2BC15 H2BFD HIST1H2BN AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q99877 Y41 Sugiyama H2BC15 H2BFD HIST1H2BN KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99877 Y43 Sugiyama H2BC15 H2BFD HIST1H2BN QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q99879 Y38 Sugiyama H2BC14 H2BFE HIST1H2BM AINKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q99879 Y41 Sugiyama H2BC14 H2BFE HIST1H2BM KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99879 Y43 Sugiyama H2BC14 H2BFE HIST1H2BM QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q99880 Y38 Sugiyama H2BC13 H2BFC HIST1H2BL AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q99880 Y41 Sugiyama H2BC13 H2BFC HIST1H2BL KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99880 Y43 Sugiyama H2BC13 H2BFC HIST1H2BL QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM
Q9BQE3 Y432 Sugiyama TUBA1C TUBA6 GMEEGEFSEAREDMAALEKDyEEVGADsADGEDEGEEy___
Q9BS40 Y20 Sugiyama LXN _MEIPPTNYPASRAALVAQNyINyQQGTPHRVFEVQKVKQA
Q9BS40 Y23 Sugiyama LXN IPPTNYPASRAALVAQNyINyQQGTPHRVFEVQKVKQAsME
Q9BU89 Y290 Sugiyama DOHH HLRC1 RESCEVALDMyEHETGRAFQyADGLEQLRGAPS________
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BYX7 Y362 Sugiyama POTEKP ACTBL3 FKSG30 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q9GZT8 Y175 Sugiyama NIF3L1 ALS2CR1 MDS015 My018 PSKAPNyPTEGNHRVEFNVNytQDLDKVMSAVKGIDGVsVT
Q9H2U1 Y169 Sugiyama DHX36 DDX36 KIAA1488 MLEL1 RHAU NQEKKMFRIRNRsyIDRDsEyLLQENEPDGtLDQKLLEDLQ
Q9H788 Y131 Sugiyama SH2D4A PPP1R38 SH2A EEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKDIWKKVAE
Q9H814 T151 Sugiyama PHAX RNUXA ATELGILGMEGTIDRsRQsEtyNyLLAKKLRKESQEHTKDL
Q9H814 Y154 Sugiyama PHAX RNUXA LGILGMEGTIDRsRQsEtyNyLLAKKLRKESQEHTKDLDKE
Q9HAP6 Y118 Sugiyama LIN7B MALS2 VELI2 UNQ3116/PRO10200 KTDEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLKRGD
Q9HB71 Y165 Sugiyama CACYBP S100A6BP SIP PNAS-107 VKTDTVLILCRKKVENTRWDyLtQVEKECKEKEKPsYDtEt
Q9HCN8 Y81 Sugiyama SDF2L1 UNQ1941/PRO4424 GSGSGQQSVtGVEAsDDANSyWRIRGGSEGGCPRGSPVRCG
Q9NQA5 Y647 Sugiyama TRPV5 ECAC1 DRWFLRVENHNDQNPLRVLRyVEVFKNsDKEDDQEHPSEKQ
Q9NRX4 Y116 Sugiyama PHPT1 PHP14 CGI-202 HSPC141 AyGPAQHAISTEKIKAKyPDyEVtWANDGy___________
Q9NUP9 Y118 Sugiyama LIN7C MALS3 VELI3 KTEEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLKRGD
Q9NVS9 Y195 Sugiyama PNPO SSVIPDREYLRKKNEELEQLyQDQEVPKPKSWGGYVLYPQV
Q9NW64 Y116 Sugiyama RBM22 ZC3H16 199G4 VRDAGLSFKDDMPKSDVNKEyyTQNMEREISNsDGTRPVGM
Q9NWS0 Y194 Sugiyama PIH1D1 NOP17 IsQQNIRSEQRPRIQELGDLytPAPGRAESGPEKPHLNLWL
Q9NYF8 Y408 Sugiyama BCLAF1 BTF KIAA0164 EsGKQKFNDsEGDDtEEtEDyRQFRKsVLADQGKsFATAsH
Q9NYU2 Y1516 Sugiyama UGGT1 GT UGCGL1 UGGT UGT1 UGTR PMTKEPKLEAAVRIVPEWQDyDQEIKQLQIRFQKEKETGAL
Q9NZH5 Y111 Sugiyama PTTG2 KKMTEKTVKTKSSVPASDDAyPEIEKFFPFNLLDFESFDLP
Q9UBR2 Y76 Sugiyama CTSZ YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA
Q9UBS4 Y352 Sugiyama DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080 TEEAREGIKQLLKQGSVQKVyNGLQGY______________
Q9UHI6 Y659 Sugiyama DDX20 DP103 GEMIN3 RVPVLASSsQsGDsEsDSDSySSRTSSQSKGNKsyLEGssD
Q9UHX1 Y269 Sugiyama PUF60 FIR ROBPI SIAHBP1 FGKIKSCTLARDPTTGKHKGyGFIEyEKAQSSQDAVSSMNL
Q9UI15 Y192 Sugiyama TAGLN3 NP25 NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________
Q9UJU6 Y16 Sugiyama DBNL CMAP SH3P7 PP5423 _____MAANLSRNGPALQEAyVRVVtEKsPtDWALFTyEGN
Q9UKJ3 Y90 Sugiyama GPATCH8 GPATC8 KIAA0553 IPIVVKYDVMGMGRMEMELDyAEDATERRRVLEVEKEDTEE
Q9UKV3 Y1086 Sugiyama ACIN1 ACINUS KIAA0670 RTALHGVKWPQSNPKFLCADyAEQDELDyHRGLLVDRPsEt
Q9UMS0 Y194 Sugiyama NFU1 HIRIP5 CGI-33 KELLDTRIRPTVQEDGGDVIyKGFEDGIVQLKLQGSCTSCP
Q9UNF0 Y267 Sugiyama PACSIN2 VLLEVQKHLDLSNVAGYKAIyHDLEQsIRAADAVEDLRWFR
Q9UNN5 Y515 Sugiyama FAF1 UBXD12 UBXN3A CGI-03 IKDEDEREARENVKREQDEAyRLsLEADRAKREAHEREMAE
Q9UQ80 Y343 Sugiyama PA2G4 EBP1 VLLMPNGPMRITsGPFEPDLyKsEMEVQDAELKALLQssAs
Q9UQ80 Y98 Sugiyama PA2G4 EBP1 TSISVNNCVCHFsPLKSDQDyILKEGDLVKIDLGVHVDGFI
Q9Y230 Y446 Sugiyama RUVBL2 INO80J TIP48 TIP49B CGI-46 IKRVysLFLDEsRSTQYMKEyQDAFLFNELKGEtMDTS___
Q9Y237 S72 Sugiyama PIN4 MEAMEKLKSGMRFNEVAAQysEDKARQGGDLGWMTRGSMVG
Q9Y281 Y82 Sugiyama CFL2 DTVEDPYtsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFI
Q9Y2T7 Y107 Sugiyama YBX2 CSDA3 MSY2 KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
Q9Y2W2 Y236 Sugiyama WBP11 NPWBP SIPP1 SNP70 GRKVGFALDLPPRRRDEDMLysPELAQRGHDDDVSSTSEDD
Q9Y394 Y330 Sugiyama DHRS7 DHRS7A RETSDR4 SDR34C1 CGI-86 UNQ285/PRO3448 NKMGKKRIENFKSGVDADssyFKIFKTKHD___________
Q9Y3D8 Y31 Sugiyama AK6 CINAP AD-004 CGI-137 TPGVGKTTLGKELASKSGLKyINVGDLAREEQLYDGYDEEY
Q9Y3F4 Y114 Sugiyama STRAP MAWD UNRIP LMTLAHKHIVKtVDFtQDSNyLLtGGQDKLLRIYDLNKPEA
Q9Y5Q8 Y393 Sugiyama GTF3C5 CDABP0017 SGtsGARKPASSKYKLKDSVyIFREGALPPYRQMFYQLCDL
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y639 Y216 Sugiyama NPTN SDFR1 SDR1 KNASNMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKA
Q9Y639 Y220 Sugiyama NPTN SDFR1 SDR1 NMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKAAPDI
Q9Y696 Y244 Sugiyama CLIC4 AysRDEFtNtCPsDKEVEIAysDVAKRLTK___________
Site Promiscuity

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Cell-Cell communication R-HSA-1500931 1.110223e-16 15.955 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.186340e-14 13.497 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.130030e-14 13.384 0 0
Packaging Of Telomere Ends R-HSA-171306 1.147971e-13 12.940 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.147971e-13 12.940 0 0
Adherens junctions interactions R-HSA-418990 1.466605e-13 12.834 0 0
DNA methylation R-HSA-5334118 2.153833e-13 12.667 0 0
HDACs deacetylate histones R-HSA-3214815 2.619016e-13 12.582 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.985079e-13 12.702 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 2.426948e-13 12.615 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.157474e-13 12.501 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.157474e-13 12.501 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 5.181411e-13 12.286 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 6.833423e-13 12.165 0 0
Cell junction organization R-HSA-446728 1.218692e-12 11.914 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.163514e-12 11.934 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 1.163514e-12 11.934 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.436073e-12 11.843 0 0
Cell-cell junction organization R-HSA-421270 1.673217e-12 11.776 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.929679e-12 11.715 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.208012e-12 11.656 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 2.462586e-12 11.609 0 0
Cleavage of the damaged purine R-HSA-110331 2.462586e-12 11.609 0 0
Depurination R-HSA-73927 3.125056e-12 11.505 0 0
Meiotic synapsis R-HSA-1221632 3.831380e-12 11.417 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 4.952039e-12 11.305 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 4.952039e-12 11.305 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 6.186607e-12 11.209 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 8.817058e-12 11.055 1 1
Cleavage of the damaged pyrimidine R-HSA-110329 9.520496e-12 11.021 0 0
Depyrimidination R-HSA-73928 9.520496e-12 11.021 0 0
Defective pyroptosis R-HSA-9710421 1.173162e-11 10.931 0 0
Nucleosome assembly R-HSA-774815 1.759193e-11 10.755 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.759193e-11 10.755 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.842415e-11 10.735 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.141431e-11 10.669 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 2.770351e-11 10.557 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 2.734535e-11 10.563 1 1
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.910816e-11 10.536 1 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 4.682965e-11 10.329 0 0
Meiotic recombination R-HSA-912446 5.422807e-11 10.266 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 5.961498e-11 10.225 1 0
RNA Polymerase I Promoter Escape R-HSA-73772 6.465639e-11 10.189 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 7.685497e-11 10.114 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.108525e-11 10.041 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.747861e-10 9.757 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.929517e-10 9.715 1 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.043818e-10 9.690 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.384042e-10 9.623 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.140098e-10 9.503 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 3.220969e-10 9.492 0 0
Meiosis R-HSA-1500620 4.530040e-10 9.344 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 5.725884e-10 9.242 0 0
DNA Double Strand Break Response R-HSA-5693606 6.577547e-10 9.182 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.856449e-10 9.006 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.016121e-09 8.993 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.123763e-09 8.949 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.123763e-09 8.949 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.278978e-09 8.893 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.362122e-09 8.866 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.410152e-09 8.851 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.648236e-09 8.783 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 2.110245e-09 8.676 0 0
RNA Polymerase I Transcription R-HSA-73864 2.684959e-09 8.571 0 0
Signal Transduction R-HSA-162582 2.738169e-09 8.563 1 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 3.395927e-09 8.469 0 0
Processing of DNA double-strand break ends R-HSA-5693607 3.810977e-09 8.419 0 0
Amyloid fiber formation R-HSA-977225 3.810977e-09 8.419 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 5.222808e-09 8.282 0 0
Activation of HOX genes during differentiation R-HSA-5619507 5.222808e-09 8.282 0 0
PIP3 activates AKT signaling R-HSA-1257604 8.165907e-09 8.088 1 1
DNA Replication Pre-Initiation R-HSA-69002 8.284964e-09 8.082 0 0
Diseases of programmed cell death R-HSA-9645723 9.141446e-09 8.039 0 0
Base Excision Repair R-HSA-73884 1.123850e-08 7.949 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.180737e-08 7.928 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.190514e-08 7.924 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 2.020934e-08 7.694 0 0
Mitotic Prophase R-HSA-68875 2.507940e-08 7.601 0 0
Telomere Maintenance R-HSA-157579 2.699387e-08 7.569 0 0
HATs acetylate histones R-HSA-3214847 3.244294e-08 7.489 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 4.019279e-08 7.396 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 4.019279e-08 7.396 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 4.019279e-08 7.396 0 0
Regulation of endogenous retroelements R-HSA-9842860 4.245798e-08 7.372 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.245798e-08 7.372 0 0
Reproduction R-HSA-1474165 6.300851e-08 7.201 0 0
Intracellular signaling by second messengers R-HSA-9006925 6.546339e-08 7.184 1 0
Gene Silencing by RNA R-HSA-211000 7.107324e-08 7.148 0 0
ESR-mediated signaling R-HSA-8939211 1.164319e-07 6.934 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.251585e-07 6.903 0 0
Homology Directed Repair R-HSA-5693538 1.978318e-07 6.704 0 0
Chromosome Maintenance R-HSA-73886 2.465782e-07 6.608 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.621140e-07 6.582 1 0
Regulation of T cell activation by CD28 family R-HSA-388841 2.860130e-07 6.544 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 2.847147e-07 6.546 0 0
Protein ubiquitination R-HSA-8852135 3.053656e-07 6.515 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.353013e-07 6.475 0 0
DNA Replication R-HSA-69306 3.353013e-07 6.475 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 3.563825e-07 6.448 0 0
G2/M Checkpoints R-HSA-69481 4.037922e-07 6.394 0 0
HCMV Early Events R-HSA-9609690 5.674909e-07 6.246 0 0
Cellular Senescence R-HSA-2559583 1.608209e-06 5.794 0 0
Regulation of KIT signaling R-HSA-1433559 1.621515e-06 5.790 0 0
Signal regulatory protein family interactions R-HSA-391160 1.621515e-06 5.790 0 0
Developmental Biology R-HSA-1266738 2.008257e-06 5.697 0 0
HCMV Late Events R-HSA-9610379 2.990695e-06 5.524 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.419844e-06 5.466 0 0
Chromatin modifying enzymes R-HSA-3247509 3.488043e-06 5.457 0 0
Signaling by NOTCH R-HSA-157118 4.476472e-06 5.349 0 0
RAF/MAP kinase cascade R-HSA-5673001 5.813247e-06 5.236 1 1
Chromatin organization R-HSA-4839726 6.424982e-06 5.192 0 0
Regulation of signaling by CBL R-HSA-912631 6.495155e-06 5.187 0 0
HCMV Infection R-HSA-9609646 6.682075e-06 5.175 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 6.782475e-06 5.169 0 0
Ub-specific processing proteases R-HSA-5689880 7.119339e-06 5.148 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 7.468383e-06 5.127 1 0
TCF dependent signaling in response to WNT R-HSA-201681 1.137751e-05 4.944 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 1.141168e-05 4.943 0 0
Immune System R-HSA-168256 1.395074e-05 4.855 0 0
PECAM1 interactions R-HSA-210990 1.670923e-05 4.777 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.720340e-05 4.764 0 0
Signaling by SCF-KIT R-HSA-1433557 1.920760e-05 4.717 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.720340e-05 4.764 0 0
Signaling by VEGF R-HSA-194138 2.032129e-05 4.692 0 0
Co-inhibition by PD-1 R-HSA-389948 2.376221e-05 4.624 0 0
MAPK family signaling cascades R-HSA-5683057 3.831509e-05 4.417 1 0
FLT3 signaling through SRC family kinases R-HSA-9706374 3.902801e-05 4.409 0 0
DCC mediated attractive signaling R-HSA-418885 5.441835e-05 4.264 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 6.149917e-05 4.211 0 0
Integrin signaling R-HSA-354192 6.485021e-05 4.188 0 0
Signaling by NTRKs R-HSA-166520 7.473163e-05 4.126 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 7.553344e-05 4.122 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 8.188316e-05 4.087 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 8.188316e-05 4.087 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.131074e-04 3.947 0 0
Adaptive Immune System R-HSA-1280218 1.409591e-04 3.851 0 0
Signaling by Interleukins R-HSA-449147 1.709643e-04 3.767 0 0
Activation of TRKA receptors R-HSA-187015 1.752033e-04 3.756 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 1.752033e-04 3.756 0 0
Deubiquitination R-HSA-5688426 1.761563e-04 3.754 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 2.314084e-04 3.636 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 2.230009e-04 3.652 0 0
Cell Cycle Checkpoints R-HSA-69620 1.932311e-04 3.714 0 0
Signaling by KIT in disease R-HSA-9669938 2.385324e-04 3.622 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 2.385324e-04 3.622 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 2.672031e-04 3.573 0 0
Epigenetic regulation of gene expression R-HSA-212165 3.033383e-04 3.518 0 0
M Phase R-HSA-68886 3.685873e-04 3.433 0 0
Disease R-HSA-1643685 4.199771e-04 3.377 1 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 4.419102e-04 3.355 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.419102e-04 3.355 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 4.661991e-04 3.331 0 0
Cell Cycle, Mitotic R-HSA-69278 5.036061e-04 3.298 0 0
Regulation of gene expression in beta cells R-HSA-210745 5.501783e-04 3.259 0 0
Signaling by WNT R-HSA-195721 5.929577e-04 3.227 0 0
Downstream signal transduction R-HSA-186763 6.760762e-04 3.170 0 0
DNA Repair R-HSA-73894 7.443747e-04 3.128 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.461112e-04 3.127 0 0
Signaling by ERBB2 R-HSA-1227986 8.192219e-04 3.087 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 8.520823e-04 3.070 0 0
Signaling by PTK6 R-HSA-8848021 9.914019e-04 3.004 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 9.914019e-04 3.004 0 0
GPVI-mediated activation cascade R-HSA-114604 1.174795e-03 2.930 0 0
Platelet activation, signaling and aggregation R-HSA-76002 1.187459e-03 2.925 0 0
TRKA activation by NGF R-HSA-187042 1.322239e-03 2.879 0 0
MET activates PTPN11 R-HSA-8865999 1.322239e-03 2.879 0 0
MET promotes cell motility R-HSA-8875878 1.386481e-03 2.858 0 0
Parasite infection R-HSA-9664407 1.463815e-03 2.835 0 0
Leishmania phagocytosis R-HSA-9664417 1.463815e-03 2.835 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 1.463815e-03 2.835 0 0
Interleukin-2 family signaling R-HSA-451927 1.623437e-03 2.790 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.701465e-03 2.769 0 0
FLT3 Signaling R-HSA-9607240 1.751865e-03 2.756 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.804308e-03 2.744 0 0
Infectious disease R-HSA-5663205 1.823447e-03 2.739 0 0
Cell Cycle R-HSA-1640170 1.839880e-03 2.735 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.336296e-03 2.631 0 0
Netrin-1 signaling R-HSA-373752 2.336296e-03 2.631 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.440141e-03 2.613 0 0
Signaling by MET R-HSA-6806834 2.516244e-03 2.599 0 0
NTRK2 activates RAC1 R-HSA-9032759 2.556174e-03 2.592 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 2.556174e-03 2.592 0 0
Reelin signalling pathway R-HSA-8866376 2.556174e-03 2.592 0 0
Cytokine Signaling in Immune system R-HSA-1280215 2.636648e-03 2.579 0 0
Apoptotic execution phase R-HSA-75153 2.673535e-03 2.573 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.027292e-03 2.519 0 0
Co-stimulation by CD28 R-HSA-389356 3.042734e-03 2.517 0 0
Developmental Cell Lineages R-HSA-9734767 3.232933e-03 2.490 0 0
Degradation of CDH1 R-HSA-9766229 3.239766e-03 2.489 0 0
NGF-independant TRKA activation R-HSA-187024 3.315814e-03 2.479 0 0
Generic Transcription Pathway R-HSA-212436 3.941426e-03 2.404 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 4.550725e-03 2.342 0 0
Viral Infection Pathways R-HSA-9824446 4.619183e-03 2.335 0 0
EPH-Ephrin signaling R-HSA-2682334 4.685785e-03 2.329 0 0
MET activates PTK2 signaling R-HSA-8874081 4.851348e-03 2.314 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 4.851348e-03 2.314 0 0
Signaling by EGFR R-HSA-177929 4.867243e-03 2.313 0 0
NRAGE signals death through JNK R-HSA-193648 4.867243e-03 2.313 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 4.879361e-03 2.312 0 0
Hemostasis R-HSA-109582 5.002460e-03 2.301 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 5.110336e-03 2.292 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.110336e-03 2.292 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 6.141270e-03 2.212 0 0
MET receptor recycling R-HSA-8875656 6.141270e-03 2.212 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 6.141270e-03 2.212 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 6.141270e-03 2.212 0 0
DAP12 signaling R-HSA-2424491 6.700537e-03 2.174 0 0
Regulation of CDH1 Function R-HSA-9764561 5.137222e-03 2.289 0 0
Signaling by PDGF R-HSA-186797 6.638101e-03 2.178 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 6.317282e-03 2.199 1 0
Interleukin-18 signaling R-HSA-9012546 6.141270e-03 2.212 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 6.141270e-03 2.212 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 5.731135e-03 2.242 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 6.396357e-03 2.194 0 0
Regulation of beta-cell development R-HSA-186712 5.706913e-03 2.244 0 0
GP1b-IX-V activation signalling R-HSA-430116 7.258740e-03 2.139 0 0
IGF1R signaling cascade R-HSA-2428924 7.311742e-03 2.136 1 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 7.664851e-03 2.115 1 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 7.664851e-03 2.115 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 8.460846e-03 2.073 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 8.460846e-03 2.073 0 0
PI3K/AKT activation R-HSA-198203 8.460846e-03 2.073 0 0
MITF-M-dependent gene expression R-HSA-9856651 9.040676e-03 2.044 0 0
RAF activation R-HSA-5673000 9.529687e-03 2.021 0 0
Interleukin-2 signaling R-HSA-9020558 9.745723e-03 2.011 0 0
Death Receptor Signaling R-HSA-73887 1.006581e-02 1.997 0 0
Signalling to ERKs R-HSA-187687 1.016682e-02 1.993 0 0
Drug resistance of FLT3 mutants R-HSA-9702506 1.044038e-02 1.981 0 0
Drug resistance of KIT mutants R-HSA-9669937 1.044038e-02 1.981 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.044038e-02 1.981 0 0
KIT mutants bind TKIs R-HSA-9669921 1.044038e-02 1.981 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.044038e-02 1.981 0 0
FLT3 mutants bind TKIs R-HSA-9702509 1.044038e-02 1.981 0 0
semaxanib-resistant FLT3 mutants R-HSA-9702577 1.044038e-02 1.981 0 0
gilteritinib-resistant FLT3 mutants R-HSA-9702590 1.044038e-02 1.981 0 0
Dasatinib-resistant KIT mutants R-HSA-9669914 1.044038e-02 1.981 0 0
Sorafenib-resistant KIT mutants R-HSA-9669936 1.044038e-02 1.981 0 0
pexidartinib-resistant FLT3 mutants R-HSA-9702605 1.044038e-02 1.981 0 0
sorafenib-resistant FLT3 mutants R-HSA-9702624 1.044038e-02 1.981 0 0
crenolanib-resistant FLT3 mutants R-HSA-9702581 1.044038e-02 1.981 0 0
Imatinib-resistant KIT mutants R-HSA-9669917 1.044038e-02 1.981 0 0
tamatinib-resistant FLT3 mutants R-HSA-9703009 1.044038e-02 1.981 0 0
KW2449-resistant FLT3 mutants R-HSA-9702569 1.044038e-02 1.981 0 0
lestaurtinib-resistant FLT3 mutants R-HSA-9702596 1.044038e-02 1.981 0 0
tandutinib-resistant FLT3 mutants R-HSA-9702636 1.044038e-02 1.981 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.044038e-02 1.981 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.044038e-02 1.981 0 0
midostaurin-resistant FLT3 mutants R-HSA-9702600 1.044038e-02 1.981 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.044038e-02 1.981 0 0
quizartinib-resistant FLT3 mutants R-HSA-9702620 1.044038e-02 1.981 0 0
Masitinib-resistant KIT mutants R-HSA-9669924 1.044038e-02 1.981 0 0
linifanib-resistant FLT3 mutants R-HSA-9702998 1.044038e-02 1.981 0 0
ponatinib-resistant FLT3 mutants R-HSA-9702614 1.044038e-02 1.981 0 0
Regorafenib-resistant KIT mutants R-HSA-9669929 1.044038e-02 1.981 0 0
sunitinib-resistant FLT3 mutants R-HSA-9702632 1.044038e-02 1.981 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.044038e-02 1.981 0 0
Nilotinib-resistant KIT mutants R-HSA-9669926 1.044038e-02 1.981 0 0
Sunitinib-resistant KIT mutants R-HSA-9669934 1.044038e-02 1.981 0 0
RUNX2 regulates bone development R-HSA-8941326 1.082815e-02 1.965 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.089852e-02 1.963 0 0
Cellular responses to stimuli R-HSA-8953897 1.100723e-02 1.958 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.151385e-02 1.939 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.206383e-02 1.919 0 0
RNA Polymerase II Transcription R-HSA-73857 1.227943e-02 1.911 0 0
Interleukin-12 signaling R-HSA-9020591 1.230682e-02 1.910 0 0
Signaling by LTK R-HSA-9842663 1.255646e-02 1.901 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.734832e-02 1.761 0 0
Negative regulation of FLT3 R-HSA-9706369 1.909221e-02 1.719 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.909221e-02 1.719 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.531243e-02 1.815 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.407873e-02 1.851 0 0
MAP2K and MAPK activation R-HSA-5674135 1.531243e-02 1.815 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 1.567659e-02 1.805 0 0
Prolonged ERK activation events R-HSA-169893 1.909221e-02 1.719 0 0
DAP12 interactions R-HSA-2172127 1.789133e-02 1.747 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.808943e-02 1.743 0 0
Spry regulation of FGF signaling R-HSA-1295596 1.734832e-02 1.761 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.909221e-02 1.719 0 0
Signaling by FGFR4 R-HSA-5654743 1.700653e-02 1.769 1 0
Signaling by FGFR3 R-HSA-5654741 1.880136e-02 1.726 0 0
Axon guidance R-HSA-422475 1.688627e-02 1.772 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.571608e-02 1.804 0 0
Signaling by ALK R-HSA-201556 1.295890e-02 1.887 0 0
G alpha (12/13) signalling events R-HSA-416482 1.330749e-02 1.876 0 0
Interleukin-12 family signaling R-HSA-447115 1.908232e-02 1.719 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.973666e-02 1.705 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.973666e-02 1.705 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.973666e-02 1.705 0 0
Signaling by RAS mutants R-HSA-6802949 1.973666e-02 1.705 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.069727e-02 1.684 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 2.077240e-02 1.683 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 2.090660e-02 1.680 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 2.278984e-02 1.642 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.278984e-02 1.642 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.278984e-02 1.642 0 0
PI3K Cascade R-HSA-109704 2.373106e-02 1.625 1 1
FCGR activation R-HSA-2029481 2.392113e-02 1.621 0 0
GAB1 signalosome R-HSA-180292 2.474031e-02 1.607 0 0
Ephrin signaling R-HSA-3928664 2.474031e-02 1.607 0 0
Nephron development R-HSA-9831926 2.474031e-02 1.607 0 0
Nervous system development R-HSA-9675108 2.600528e-02 1.585 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.779348e-02 1.556 0 0
Negative regulation of MET activity R-HSA-6807004 2.883662e-02 1.540 0 0
Formation of definitive endoderm R-HSA-9823730 2.883662e-02 1.540 0 0
Signaling by FGFR1 R-HSA-5654736 3.048156e-02 1.516 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 3.058295e-02 1.515 0 0
Signalling to RAS R-HSA-167044 3.097936e-02 1.509 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 3.097936e-02 1.509 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 3.097936e-02 1.509 0 0
NTRK3 as a dependence receptor R-HSA-9603505 3.099717e-02 1.509 0 0
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935 3.099717e-02 1.509 0 0
Signaling by extracellular domain mutants of KIT R-HSA-9680187 3.099717e-02 1.509 0 0
Signaling by kinase domain mutants of KIT R-HSA-9669933 3.099717e-02 1.509 0 0
Dectin-2 family R-HSA-5621480 3.169477e-02 1.499 0 0
IRS-mediated signalling R-HSA-112399 3.169477e-02 1.499 1 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.318311e-02 1.479 0 0
Response of endothelial cells to shear stress R-HSA-9860931 3.380926e-02 1.471 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.544639e-02 1.450 0 0
Regulation of PTEN gene transcription R-HSA-8943724 3.548426e-02 1.450 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.776774e-02 1.423 0 0
NCAM signaling for neurite out-growth R-HSA-375165 3.813464e-02 1.419 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 3.900746e-02 1.409 0 0
Semaphorin interactions R-HSA-373755 3.949677e-02 1.403 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 4.014570e-02 1.396 0 0
Leishmania infection R-HSA-9658195 4.060498e-02 1.391 0 0
Parasitic Infection Pathways R-HSA-9824443 4.060498e-02 1.391 0 0
Insulin receptor signalling cascade R-HSA-74751 4.088339e-02 1.388 1 0
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357 4.111581e-02 1.386 0 0
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046 4.111581e-02 1.386 0 0
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909 4.111581e-02 1.386 0 0
NTF3 activates NTRK3 signaling R-HSA-9034013 4.111581e-02 1.386 0 0
Neurophilin interactions with VEGF and VEGFR R-HSA-194306 4.111581e-02 1.386 0 0
Apoptosis R-HSA-109581 4.224951e-02 1.374 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 4.229437e-02 1.374 0 0
Sema4D in semaphorin signaling R-HSA-400685 4.257886e-02 1.371 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 4.468263e-02 1.350 0 0
Signaling by EGFR in Cancer R-HSA-1643713 4.506582e-02 1.346 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 4.506582e-02 1.346 0 0
Cellular responses to stress R-HSA-2262752 4.663224e-02 1.331 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 5.019568e-02 1.299 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 5.112940e-02 1.291 0 0
PLC-gamma1 signalling R-HSA-167021 5.112940e-02 1.291 0 0
MET interacts with TNS proteins R-HSA-8875513 5.112940e-02 1.291 0 0
Signalling to STAT3 R-HSA-198745 5.112940e-02 1.291 0 0
MET activates STAT3 R-HSA-8875791 5.112940e-02 1.291 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 5.126503e-02 1.290 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 5.250844e-02 1.280 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 5.283590e-02 1.277 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.283590e-02 1.277 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 5.283590e-02 1.277 1 1
Signaling by Erythropoietin R-HSA-9006335 5.283590e-02 1.277 0 0
Cell surface interactions at the vascular wall R-HSA-202733 5.502276e-02 1.259 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 5.552456e-02 1.256 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 5.826037e-02 1.235 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 6.103903e-02 1.214 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 6.103903e-02 1.214 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 7.084578e-02 1.150 0 0
IRS activation R-HSA-74713 7.084578e-02 1.150 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 8.055070e-02 1.094 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 8.055070e-02 1.094 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 8.055070e-02 1.094 0 0
Phosphorylation of Emi1 R-HSA-176417 8.055070e-02 1.094 0 0
Defective CSF2RA causes SMDP4 R-HSA-5688890 8.055070e-02 1.094 0 0
Defective CSF2RB causes SMDP5 R-HSA-5688849 8.055070e-02 1.094 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 8.055070e-02 1.094 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 9.015485e-02 1.045 0 0
STAT5 Activation R-HSA-9645135 9.015485e-02 1.045 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 9.965926e-02 1.001 0 0
IFNG signaling activates MAPKs R-HSA-9732724 9.965926e-02 1.001 0 0
SOS-mediated signalling R-HSA-112412 9.965926e-02 1.001 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.090650e-01 0.962 0 0
Type I hemidesmosome assembly R-HSA-446107 1.090650e-01 0.962 0 0
ARMS-mediated activation R-HSA-170984 1.183730e-01 0.927 0 0
Interleukin-21 signaling R-HSA-9020958 1.183730e-01 0.927 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 6.673818e-02 1.176 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 6.673818e-02 1.176 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 9.965926e-02 1.001 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 1.036487e-01 0.984 0 0
Chaperonin-mediated protein folding R-HSA-390466 8.113746e-02 1.091 0 0
Oncogenic MAPK signaling R-HSA-6802957 7.541203e-02 1.123 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.313034e-02 1.031 0 0
Regulation of gap junction activity R-HSA-191650 6.103903e-02 1.214 0 0
Signaling by MST1 R-HSA-8852405 8.055070e-02 1.094 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 1.090650e-01 0.962 0 0
Generation of second messenger molecules R-HSA-202433 8.794394e-02 1.056 0 0
PTK6 Expression R-HSA-8849473 9.965926e-02 1.001 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 6.965018e-02 1.157 0 0
MET Receptor Activation R-HSA-6806942 9.015485e-02 1.045 0 0
FLT3 signaling in disease R-HSA-9682385 7.559611e-02 1.122 0 0
Protein folding R-HSA-391251 9.313034e-02 1.031 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 7.260321e-02 1.139 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 6.103903e-02 1.214 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 6.965018e-02 1.157 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 8.055070e-02 1.094 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 9.965926e-02 1.001 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 1.183730e-01 0.927 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 6.386841e-02 1.195 0 0
Signaling by FGFR1 in disease R-HSA-5655302 9.432830e-02 1.025 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 6.103903e-02 1.214 0 0
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403 7.084578e-02 1.150 0 0
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399 8.055070e-02 1.094 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 8.055070e-02 1.094 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 6.230791e-02 1.205 0 0
Negative regulation of MAPK pathway R-HSA-5675221 9.432830e-02 1.025 0 0
Signaling by Insulin receptor R-HSA-74752 9.313034e-02 1.031 1 0
Signaling by FGFR2 R-HSA-5654738 6.629043e-02 1.179 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 9.111947e-02 1.040 0 0
Signaling by FGFR R-HSA-190236 1.079827e-01 0.967 1 0
VEGF ligand-receptor interactions R-HSA-194313 8.055070e-02 1.094 0 0
Netrin mediated repulsion signals R-HSA-418886 9.965926e-02 1.001 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 1.090650e-01 0.962 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.607738e-02 1.065 0 0
Gene expression (Transcription) R-HSA-74160 6.526589e-02 1.185 0 0
RET signaling R-HSA-8853659 7.559611e-02 1.122 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 8.055070e-02 1.094 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 8.055070e-02 1.094 0 0
Nef and signal transduction R-HSA-164944 9.015485e-02 1.045 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 1.090650e-01 0.962 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 1.183730e-01 0.927 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 1.036487e-01 0.984 0 0
Innate Immune System R-HSA-168249 7.449976e-02 1.128 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.183730e-01 0.927 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.041444e-01 0.982 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 8.905441e-02 1.050 0 0
Programmed Cell Death R-HSA-5357801 8.967353e-02 1.047 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.275844e-01 0.894 0 0
Regulation of CDH11 function R-HSA-9762292 1.275844e-01 0.894 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.275844e-01 0.894 0 0
Signal attenuation R-HSA-74749 1.275844e-01 0.894 0 0
Receptor Mediated Mitophagy R-HSA-8934903 1.275844e-01 0.894 0 0
Signaling by Leptin R-HSA-2586552 1.275844e-01 0.894 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.283206e-01 0.892 0 0
Smooth Muscle Contraction R-HSA-445355 1.350737e-01 0.869 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.367000e-01 0.864 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 1.367000e-01 0.864 0 0
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290 1.367000e-01 0.864 0 0
Dissolution of Fibrin Clot R-HSA-75205 1.367000e-01 0.864 0 0
FCERI mediated MAPK activation R-HSA-2871796 1.425786e-01 0.846 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 1.445191e-01 0.840 0 0
Leishmania parasite growth and survival R-HSA-9664433 1.445191e-01 0.840 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 1.457210e-01 0.836 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.457210e-01 0.836 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 1.457210e-01 0.836 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 1.530400e-01 0.815 0 0
MET activates RAS signaling R-HSA-8851805 1.546483e-01 0.811 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.546483e-01 0.811 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.546483e-01 0.811 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.546483e-01 0.811 0 0
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286 1.546483e-01 0.811 0 0
Diseases associated with surfactant metabolism R-HSA-5687613 1.546483e-01 0.811 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.546483e-01 0.811 0 0
Pervasive developmental disorders R-HSA-9005895 1.546483e-01 0.811 0 0
Disorders of Nervous System Development R-HSA-9697154 1.546483e-01 0.811 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.546483e-01 0.811 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 1.548444e-01 0.810 0 0
Kinesins R-HSA-983189 1.603527e-01 0.795 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.634828e-01 0.787 0 0
Frs2-mediated activation R-HSA-170968 1.634828e-01 0.787 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.634828e-01 0.787 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 1.634828e-01 0.787 0 0
Interleukin-6 signaling R-HSA-1059683 1.634828e-01 0.787 0 0
CRMPs in Sema3A signaling R-HSA-399956 1.722255e-01 0.764 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.722255e-01 0.764 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.722255e-01 0.764 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 1.722255e-01 0.764 0 0
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661 1.722255e-01 0.764 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 1.722255e-01 0.764 0 0
Signaling by FGFR4 in disease R-HSA-5655291 1.722255e-01 0.764 1 1
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.808774e-01 0.743 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.808774e-01 0.743 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.808774e-01 0.743 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 1.808774e-01 0.743 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.808774e-01 0.743 0 0
p38MAPK events R-HSA-171007 1.808774e-01 0.743 0 0
Erythropoietin activates RAS R-HSA-9027284 1.808774e-01 0.743 0 0
Protein methylation R-HSA-8876725 1.808774e-01 0.743 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 1.808774e-01 0.743 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 1.824621e-01 0.739 0 0
Kidney development R-HSA-9830369 1.864067e-01 0.730 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 1.894394e-01 0.723 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.894394e-01 0.723 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 1.894394e-01 0.723 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 1.894394e-01 0.723 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 1.894394e-01 0.723 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 1.894394e-01 0.723 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 1.894394e-01 0.723 0 0
Differentiation of T cells R-HSA-9945266 1.894394e-01 0.723 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.939594e-01 0.712 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 1.979125e-01 0.704 0 0
Disorders of Developmental Biology R-HSA-9675151 1.979125e-01 0.704 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.041042e-01 0.690 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 2.062975e-01 0.686 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 2.062975e-01 0.686 0 0
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265 2.062975e-01 0.686 0 0
Signaling by Hippo R-HSA-2028269 2.062975e-01 0.686 0 0
Signaling by FGFR in disease R-HSA-1226099 2.130008e-01 0.672 1 0
Signaling by ERBB4 R-HSA-1236394 2.130008e-01 0.672 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.145953e-01 0.668 0 0
Platelet sensitization by LDL R-HSA-432142 2.145953e-01 0.668 0 0
Biosynthesis of Lipoxins (LX) R-HSA-2142700 2.145953e-01 0.668 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.145953e-01 0.668 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.145953e-01 0.668 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.145953e-01 0.668 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 2.228069e-01 0.652 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 2.228069e-01 0.652 0 0
Rap1 signalling R-HSA-392517 2.228069e-01 0.652 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 2.245117e-01 0.649 0 0
PTEN Regulation R-HSA-6807070 2.258369e-01 0.646 0 0
Integrin cell surface interactions R-HSA-216083 2.283597e-01 0.641 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 2.309331e-01 0.637 1 1
Formation of ATP by chemiosmotic coupling R-HSA-163210 2.309331e-01 0.637 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.309331e-01 0.637 0 0
Nephrin family interactions R-HSA-373753 2.309331e-01 0.637 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 2.309331e-01 0.637 0 0
Creatine metabolism R-HSA-71288 2.309331e-01 0.637 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.309331e-01 0.637 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.360690e-01 0.627 0 0
Neutrophil degranulation R-HSA-6798695 2.380437e-01 0.623 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 2.389749e-01 0.622 0 0
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896 2.389749e-01 0.622 0 0
Basigin interactions R-HSA-210991 2.389749e-01 0.622 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.469331e-01 0.607 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 2.469331e-01 0.607 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 2.469331e-01 0.607 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.469331e-01 0.607 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 2.548085e-01 0.594 0 0
Notch-HLH transcription pathway R-HSA-350054 2.548085e-01 0.594 0 0
Biosynthesis of D-series resolvins R-HSA-9018676 2.548085e-01 0.594 0 0
mTORC1-mediated signalling R-HSA-166208 2.548085e-01 0.594 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 2.548085e-01 0.594 0 0
Protein-protein interactions at synapses R-HSA-6794362 2.553970e-01 0.593 0 0
Potential therapeutics for SARS R-HSA-9679191 2.591978e-01 0.586 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.626021e-01 0.581 0 0
Termination of O-glycan biosynthesis R-HSA-977068 2.626021e-01 0.581 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.626021e-01 0.581 0 0
Biosynthesis of maresins R-HSA-9018682 2.626021e-01 0.581 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 2.626021e-01 0.581 0 0
Growth hormone receptor signaling R-HSA-982772 2.626021e-01 0.581 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 2.648258e-01 0.577 0 0
Interleukin-1 family signaling R-HSA-446652 2.648258e-01 0.577 0 0
Protein localization R-HSA-9609507 2.676456e-01 0.572 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 2.703146e-01 0.568 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 2.703146e-01 0.568 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.703146e-01 0.568 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 2.703146e-01 0.568 0 0
Interleukin-6 family signaling R-HSA-6783589 2.703146e-01 0.568 0 0
Peptide chain elongation R-HSA-156902 2.708849e-01 0.567 0 0
Autophagy R-HSA-9612973 2.761257e-01 0.559 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 2.779470e-01 0.556 0 0
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives R-HSA-9027604 2.779470e-01 0.556 0 0
Long-term potentiation R-HSA-9620244 2.779470e-01 0.556 0 0
HDMs demethylate histones R-HSA-3214842 2.779470e-01 0.556 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.779470e-01 0.556 0 0
Interleukin-7 signaling R-HSA-1266695 2.779470e-01 0.556 0 0
Myogenesis R-HSA-525793 2.854999e-01 0.544 0 0
Cristae formation R-HSA-8949613 2.929744e-01 0.533 0 0
Biosynthesis of DPAn-3 SPMs R-HSA-9025094 2.929744e-01 0.533 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 2.929744e-01 0.533 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 2.929744e-01 0.533 0 0
Signaling by BMP R-HSA-201451 2.929744e-01 0.533 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 2.929744e-01 0.533 0 0
Signaling by FGFR3 in disease R-HSA-5655332 2.929744e-01 0.533 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 3.076908e-01 0.512 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 3.076908e-01 0.512 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.076908e-01 0.512 0 0
Biosynthesis of EPA-derived SPMs R-HSA-9018679 3.076908e-01 0.512 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.095165e-01 0.509 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 3.149345e-01 0.502 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 3.149345e-01 0.502 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.149345e-01 0.502 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 3.149345e-01 0.502 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 3.149345e-01 0.502 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 3.149345e-01 0.502 1 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 3.149345e-01 0.502 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 3.149345e-01 0.502 0 0
Activation of BH3-only proteins R-HSA-114452 3.149345e-01 0.502 0 0
EGFR downregulation R-HSA-182971 3.221027e-01 0.492 0 0
Biosynthesis of DPA-derived SPMs R-HSA-9018683 3.221027e-01 0.492 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 3.286971e-01 0.483 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 3.291965e-01 0.483 0 0
Diseases of mitotic cell cycle R-HSA-9675126 3.291965e-01 0.483 0 0
G0 and Early G1 R-HSA-1538133 3.291965e-01 0.483 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 3.331276e-01 0.477 0 0
SARS-CoV-1 Infection R-HSA-9678108 3.331276e-01 0.477 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.362164e-01 0.473 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.362164e-01 0.473 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.362164e-01 0.473 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.362164e-01 0.473 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 3.362164e-01 0.473 0 0
RSV-host interactions R-HSA-9833110 3.439394e-01 0.464 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 3.500379e-01 0.456 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 3.500379e-01 0.456 0 0
NOD1/2 Signaling Pathway R-HSA-168638 3.500379e-01 0.456 0 0
Signal amplification R-HSA-392518 3.500379e-01 0.456 0 0
Mitophagy R-HSA-5205647 3.500379e-01 0.456 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 3.568410e-01 0.448 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 3.568410e-01 0.448 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 3.568410e-01 0.448 0 0
HSF1 activation R-HSA-3371511 3.635733e-01 0.439 0 0
TCR signaling R-HSA-202403 3.665898e-01 0.436 0 0
SLC-mediated transport of organic cations R-HSA-549127 3.702355e-01 0.432 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 3.833527e-01 0.416 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.871849e-01 0.412 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 3.898091e-01 0.409 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 3.898091e-01 0.409 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 3.961982e-01 0.402 0 0
Mitochondrial biogenesis R-HSA-1592230 3.999810e-01 0.398 0 0
SARS-CoV Infections R-HSA-9679506 4.010539e-01 0.397 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 4.040746e-01 0.394 0 0
MTOR signalling R-HSA-165159 4.087778e-01 0.389 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 4.149695e-01 0.382 0 0
mRNA Splicing R-HSA-72172 4.180488e-01 0.379 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 4.210967e-01 0.376 0 0
Surfactant metabolism R-HSA-5683826 4.210967e-01 0.376 0 0
Cyclin D associated events in G1 R-HSA-69231 4.210967e-01 0.376 0 0
G1 Phase R-HSA-69236 4.210967e-01 0.376 0 0
MHC class II antigen presentation R-HSA-2132295 4.217858e-01 0.375 0 0
Bacterial Infection Pathways R-HSA-9824439 4.329318e-01 0.364 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.331605e-01 0.363 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.331605e-01 0.363 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 4.390983e-01 0.357 0 0
Recycling pathway of L1 R-HSA-437239 4.390983e-01 0.357 0 0
GPER1 signaling R-HSA-9634597 4.449743e-01 0.352 0 0
Gap junction trafficking and regulation R-HSA-157858 4.507891e-01 0.346 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 4.507891e-01 0.346 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.565433e-01 0.341 0 0
Azathioprine ADME R-HSA-9748787 4.565433e-01 0.341 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 4.678726e-01 0.330 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.678726e-01 0.330 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.734489e-01 0.325 0 0
Amino acids regulate mTORC1 R-HSA-9639288 4.734489e-01 0.325 0 0
Translation initiation complex formation R-HSA-72649 4.789671e-01 0.320 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 4.789671e-01 0.320 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.789671e-01 0.320 0 0
Organelle biogenesis and maintenance R-HSA-1852241 4.793207e-01 0.319 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 4.812434e-01 0.318 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.844278e-01 0.315 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 4.898316e-01 0.310 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 4.898316e-01 0.310 0 0
TNF signaling R-HSA-75893 4.898316e-01 0.310 0 0
Macroautophagy R-HSA-1632852 4.946870e-01 0.306 0 0
Nuclear Envelope Breakdown R-HSA-2980766 4.951791e-01 0.305 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 5.004709e-01 0.301 0 0
Extracellular matrix organization R-HSA-1474244 5.040218e-01 0.298 0 0
Peroxisomal protein import R-HSA-9033241 5.057075e-01 0.296 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 5.057075e-01 0.296 0 0
Amino acid transport across the plasma membrane R-HSA-352230 5.057075e-01 0.296 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 5.108895e-01 0.292 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 5.108895e-01 0.292 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 5.108895e-01 0.292 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 5.108895e-01 0.292 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 5.108895e-01 0.292 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 5.144367e-01 0.289 0 0
MAP kinase activation R-HSA-450294 5.160176e-01 0.287 0 0
Endogenous sterols R-HSA-211976 5.160176e-01 0.287 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 5.210922e-01 0.283 0 0
Heme signaling R-HSA-9707616 5.210922e-01 0.283 0 0
Mitochondrial protein import R-HSA-1268020 5.210922e-01 0.283 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.210922e-01 0.283 0 0
Gastrulation R-HSA-9758941 5.241203e-01 0.281 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 5.261139e-01 0.279 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 5.261139e-01 0.279 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.310832e-01 0.275 0 0
Xenobiotics R-HSA-211981 5.310832e-01 0.275 0 0
Cellular response to hypoxia R-HSA-1234174 5.360008e-01 0.271 0 0
AURKA Activation by TPX2 R-HSA-8854518 5.408670e-01 0.267 0 0
PPARA activates gene expression R-HSA-1989781 5.430975e-01 0.265 0 0
SLC-mediated transport of amino acids R-HSA-9958863 5.456826e-01 0.263 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 5.493063e-01 0.260 0 0
O-linked glycosylation of mucins R-HSA-913709 5.504479e-01 0.259 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 5.504479e-01 0.259 0 0
Cellular response to starvation R-HSA-9711097 5.523886e-01 0.258 0 0
Signaling by TGFB family members R-HSA-9006936 5.585089e-01 0.253 0 0
Interleukin-17 signaling R-HSA-448424 5.598300e-01 0.252 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.644478e-01 0.248 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.644478e-01 0.248 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 5.644478e-01 0.248 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 5.644478e-01 0.248 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 5.690174e-01 0.245 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 5.735394e-01 0.241 0 0
Switching of origins to a post-replicative state R-HSA-69052 5.735394e-01 0.241 0 0
Centrosome maturation R-HSA-380287 5.824423e-01 0.235 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 5.824423e-01 0.235 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 5.824423e-01 0.235 0 0
Signaling by NOTCH1 R-HSA-1980143 5.868242e-01 0.231 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 5.911060e-01 0.228 0 0
Nuclear Receptor transcription pathway R-HSA-383280 5.954514e-01 0.225 0 0
Sensory processing of sound R-HSA-9659379 5.996976e-01 0.222 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 6.038995e-01 0.219 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 6.080576e-01 0.216 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 6.080576e-01 0.216 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 6.092821e-01 0.215 0 0
Cytoprotection by HMOX1 R-HSA-9707564 6.162439e-01 0.210 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 6.202731e-01 0.207 0 0
G2/M Transition R-HSA-69275 6.352866e-01 0.197 0 0
Post NMDA receptor activation events R-HSA-438064 6.359738e-01 0.197 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.397970e-01 0.194 0 0
Selective autophagy R-HSA-9663891 6.397970e-01 0.194 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 6.405404e-01 0.193 0 0
Mitotic G2-G2/M phases R-HSA-453274 6.405404e-01 0.193 0 0
Cilium Assembly R-HSA-5617833 6.457350e-01 0.190 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 6.473242e-01 0.189 0 0
Neurotransmitter release cycle R-HSA-112310 6.473242e-01 0.189 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 6.510289e-01 0.186 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 6.546949e-01 0.184 0 0
Mitochondrial protein degradation R-HSA-9837999 6.654649e-01 0.177 0 0
Collagen formation R-HSA-1474290 6.654649e-01 0.177 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 6.689802e-01 0.175 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.724587e-01 0.172 0 0
Eukaryotic Translation Termination R-HSA-72764 6.724587e-01 0.172 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 6.759009e-01 0.170 0 0
Signaling by ROBO receptors R-HSA-376176 6.780687e-01 0.169 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.793071e-01 0.168 0 0
Post-translational protein phosphorylation R-HSA-8957275 6.826778e-01 0.166 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 6.826778e-01 0.166 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 6.826778e-01 0.166 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 6.826778e-01 0.166 0 0
Selenocysteine synthesis R-HSA-2408557 6.925799e-01 0.160 0 0
Interleukin-1 signaling R-HSA-9020702 6.925799e-01 0.160 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.958118e-01 0.158 0 0
PI Metabolism R-HSA-1483255 6.958118e-01 0.158 0 0
Viral mRNA Translation R-HSA-192823 6.990100e-01 0.156 0 0
Muscle contraction R-HSA-397014 7.012836e-01 0.154 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 7.021747e-01 0.154 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.021747e-01 0.154 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 7.084053e-01 0.150 0 0
Platelet homeostasis R-HSA-418346 7.114718e-01 0.148 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 7.145063e-01 0.146 0 0
Synthesis of DNA R-HSA-69239 7.145063e-01 0.146 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 7.145063e-01 0.146 0 0
Signaling by ALK in cancer R-HSA-9700206 7.145063e-01 0.146 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 7.175090e-01 0.144 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 7.175090e-01 0.144 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 7.175090e-01 0.144 0 0
Stimuli-sensing channels R-HSA-2672351 7.175090e-01 0.144 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 7.204803e-01 0.142 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.234206e-01 0.141 0 0
MyD88-independent TLR4 cascade R-HSA-166166 7.234206e-01 0.141 0 0
Antimicrobial peptides R-HSA-6803157 7.263301e-01 0.139 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.292092e-01 0.137 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.292092e-01 0.137 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 7.320582e-01 0.135 0 0
SARS-CoV-2-host interactions R-HSA-9705683 7.355393e-01 0.133 0 0
Metabolism of proteins R-HSA-392499 7.357673e-01 0.133 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 7.376671e-01 0.132 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 7.404276e-01 0.131 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 7.404276e-01 0.131 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 7.431592e-01 0.129 0 0
rRNA processing R-HSA-72312 7.435666e-01 0.129 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.458623e-01 0.127 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.458623e-01 0.127 0 0
L1CAM interactions R-HSA-373760 7.458623e-01 0.127 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 7.538030e-01 0.123 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 7.538030e-01 0.123 0 0
Neuronal System R-HSA-112316 7.573855e-01 0.121 0 0
Cellular response to heat stress R-HSA-3371556 7.589592e-01 0.120 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.614969e-01 0.118 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.614969e-01 0.118 0 0
Host Interactions of HIV factors R-HSA-162909 7.664930e-01 0.115 0 0
Platelet degranulation R-HSA-114608 7.761751e-01 0.110 0 0
Post-translational protein modification R-HSA-597592 7.809854e-01 0.107 0 0
Adipogenesis R-HSA-9843745 7.877182e-01 0.104 0 0
Circadian clock R-HSA-9909396 7.899549e-01 0.102 0 0
Degradation of the extracellular matrix R-HSA-1474228 7.899549e-01 0.102 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 7.921680e-01 0.101 0 0
O-linked glycosylation R-HSA-5173105 8.028910e-01 0.095 0 0
Ribosome-associated quality control R-HSA-9948299 8.049687e-01 0.094 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 8.150349e-01 0.089 0 0
Clathrin-mediated endocytosis R-HSA-8856828 8.169853e-01 0.088 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 8.169853e-01 0.088 0 0
FCERI mediated NF-kB activation R-HSA-2871837 8.189152e-01 0.087 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 8.264348e-01 0.083 0 0
S Phase R-HSA-69242 8.264348e-01 0.083 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.336438e-01 0.079 0 0
Arachidonate metabolism R-HSA-2142753 8.336438e-01 0.079 0 0
Membrane Trafficking R-HSA-199991 8.346848e-01 0.078 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 8.388545e-01 0.076 0 0
Interferon gamma signaling R-HSA-877300 8.455506e-01 0.073 0 0
Regulation of TP53 Activity R-HSA-5633007 8.471809e-01 0.072 0 0
Selenoamino acid metabolism R-HSA-2408522 8.535330e-01 0.069 0 0
Translation R-HSA-72766 8.537696e-01 0.069 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 8.581241e-01 0.066 0 0
G alpha (s) signalling events R-HSA-418555 8.654603e-01 0.063 0 0
Influenza Infection R-HSA-168255 8.764215e-01 0.057 0 0
Transmission across Chemical Synapses R-HSA-112315 8.770234e-01 0.057 0 0
Diseases of glycosylation R-HSA-3781865 8.828166e-01 0.054 0 0
Ion channel transport R-HSA-983712 8.888826e-01 0.051 0 0
Toll-like Receptor Cascades R-HSA-168898 8.912207e-01 0.050 0 0
Mitotic Prometaphase R-HSA-68877 8.935098e-01 0.049 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.012921e-01 0.045 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 9.139250e-01 0.039 0 0
Mitotic Anaphase R-HSA-68882 9.175146e-01 0.037 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 9.183886e-01 0.037 0 0
Drug ADME R-HSA-9748784 9.192533e-01 0.037 0 0
GPCR downstream signalling R-HSA-388396 9.235973e-01 0.035 0 0
HIV Infection R-HSA-162906 9.266371e-01 0.033 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.281845e-01 0.032 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.353902e-01 0.029 0 0
Vesicle-mediated transport R-HSA-5653656 9.388657e-01 0.027 0 0
Metabolism of RNA R-HSA-8953854 9.489898e-01 0.023 0 0
Diseases of metabolism R-HSA-5668914 9.504256e-01 0.022 0 0
Cellular response to chemical stress R-HSA-9711123 9.526362e-01 0.021 0 0
Signaling by GPCR R-HSA-372790 9.560964e-01 0.019 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.574380e-01 0.019 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.592202e-01 0.018 0 0
Phospholipid metabolism R-HSA-1483257 9.645158e-01 0.016 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 9.647409e-01 0.016 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.783291e-01 0.010 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.863505e-01 0.006 0 0
Interferon Signaling R-HSA-913531 9.863505e-01 0.006 0 0
G alpha (i) signalling events R-HSA-418594 9.894603e-01 0.005 0 0
Fatty acid metabolism R-HSA-8978868 9.894603e-01 0.005 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.914822e-01 0.004 0 0
Biological oxidations R-HSA-211859 9.969963e-01 0.001 0 0
Transport of small molecules R-HSA-382551 9.985608e-01 0.001 0 0
Metabolism of lipids R-HSA-556833 9.999374e-01 0.000 0 0
Sensory Perception R-HSA-9709957 9.999989e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
betaKlotho-mediated ligand binding R-HSA-1307965 1.000000e+00 0.000 1 1
FGFR4 mutant receptor activation R-HSA-1839128 1.000000e+00 0.000 1 1
FGFR4 ligand binding and activation R-HSA-190322 1.000000e+00 0.000 1 1
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 1.000000e+00 0.000 1 1
FRS-mediated FGFR4 signaling R-HSA-5654712 1.000000e+00 0.000 1 1
SHC-mediated cascade:FGFR4 R-HSA-5654719 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
G2/M DNA damage checkpoint R-HSA-69473 1.110223e-16 15.955 0 0
Cellular response to heat stress R-HSA-3371556 6.328271e-15 14.199 0 0
Cell-Cell communication R-HSA-1500931 1.487699e-14 13.827 0 0
G2/M Checkpoints R-HSA-69481 1.487699e-14 13.827 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 3.175238e-14 13.498 0 0
Packaging Of Telomere Ends R-HSA-171306 8.815171e-14 13.055 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 8.815171e-14 13.055 0 0
DNA methylation R-HSA-5334118 1.655343e-13 12.781 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 3.983480e-13 12.400 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 5.253575e-13 12.280 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 8.949508e-13 12.048 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 8.949508e-13 12.048 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.331601e-12 11.876 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.484923e-12 11.828 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.966427e-12 11.706 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.895595e-12 11.722 0 0
Cleavage of the damaged purine R-HSA-110331 1.895595e-12 11.722 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 2.199130e-12 11.658 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 2.199130e-12 11.658 0 0
Depurination R-HSA-73927 2.405964e-12 11.619 0 0
Meiotic synapsis R-HSA-1221632 2.885803e-12 11.540 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 2.885803e-12 11.540 0 0
Attenuation phase R-HSA-3371568 3.814282e-12 11.419 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 3.814282e-12 11.419 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 3.814282e-12 11.419 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 4.766298e-12 11.322 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 4.766298e-12 11.322 0 0
Cell junction organization R-HSA-446728 6.078027e-12 11.216 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 7.338241e-12 11.134 0 0
Depyrimidination R-HSA-73928 7.338241e-12 11.134 0 0
Defective pyroptosis R-HSA-9710421 9.044543e-12 11.044 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 9.994228e-12 11.000 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.356859e-11 10.867 0 0
Nucleosome assembly R-HSA-774815 1.356859e-11 10.867 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.379652e-11 10.860 0 0
Cell Cycle Checkpoints R-HSA-69620 1.394307e-11 10.856 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.652067e-11 10.782 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.421874e-11 10.616 0 0
Cellular responses to stimuli R-HSA-8953897 3.886280e-11 10.410 0 0
HSF1 activation R-HSA-3371511 3.949641e-11 10.403 0 0
HSF1-dependent transactivation R-HSA-3371571 4.188305e-11 10.378 0 0
Meiotic recombination R-HSA-912446 4.188305e-11 10.378 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 4.994871e-11 10.301 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 5.486078e-11 10.261 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 6.324219e-11 10.199 0 0
Adherens junctions interactions R-HSA-418990 7.034628e-11 10.153 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 7.039758e-11 10.152 0 0
Cell-cell junction organization R-HSA-421270 7.173073e-11 10.144 0 0
HDACs deacetylate histones R-HSA-3214815 8.321277e-11 10.080 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.352105e-10 9.869 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.581409e-10 9.801 0 0
Infectious disease R-HSA-5663205 1.945294e-10 9.711 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 1.845075e-10 9.734 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 2.493927e-10 9.603 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.493927e-10 9.603 0 0
Meiosis R-HSA-1500620 3.437127e-10 9.464 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 4.437445e-10 9.353 0 0
Gene Silencing by RNA R-HSA-211000 4.585273e-10 9.339 0 0
DNA Double Strand Break Response R-HSA-5693606 5.098622e-10 9.293 0 0
Diseases of programmed cell death R-HSA-9645723 5.500753e-10 9.260 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 7.645470e-10 9.117 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 7.334937e-10 9.135 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 7.645470e-10 9.117 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 8.718797e-10 9.060 0 0
EPH-Ephrin signaling R-HSA-2682334 9.623096e-10 9.017 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.127934e-09 8.948 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.570664e-09 8.804 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.570664e-09 8.804 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.570664e-09 8.804 0 0
Cellular responses to stress R-HSA-2262752 1.583422e-09 8.800 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.639103e-09 8.785 0 0
Mitotic Prophase R-HSA-68875 1.881267e-09 8.726 0 0
RNA Polymerase I Transcription R-HSA-73864 2.086448e-09 8.681 0 0
HATs acetylate histones R-HSA-3214847 2.219973e-09 8.654 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.640126e-09 8.578 0 0
Processing of DNA double-strand break ends R-HSA-5693607 2.963471e-09 8.528 0 0
Amyloid fiber formation R-HSA-977225 2.963471e-09 8.528 0 0
Regulation of endogenous retroelements R-HSA-9842860 2.986400e-09 8.525 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.321801e-09 8.479 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 4.156839e-09 8.381 0 0
Viral Infection Pathways R-HSA-9824446 5.356265e-09 8.271 0 0
Estrogen-dependent gene expression R-HSA-9018519 8.926057e-09 8.049 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 9.697575e-09 8.013 0 0
Base Excision Repair R-HSA-73884 8.758997e-09 8.058 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.307557e-08 7.884 0 0
Telomere Maintenance R-HSA-157579 2.108112e-08 7.676 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 3.319539e-08 7.479 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 4.313630e-08 7.365 0 0
Activation of HOX genes during differentiation R-HSA-5619507 4.313630e-08 7.365 0 0
Reproduction R-HSA-1474165 4.838735e-08 7.315 0 0
DNA Replication Pre-Initiation R-HSA-69002 6.567933e-08 7.183 0 0
Co-inhibition by PD-1 R-HSA-389948 7.829281e-08 7.106 0 0
ESR-mediated signaling R-HSA-8939211 8.491870e-08 7.071 0 0
EPHB-mediated forward signaling R-HSA-3928662 8.646660e-08 7.063 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 9.069609e-08 7.042 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 9.814129e-08 7.008 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 1.146781e-07 6.941 0 0
Signal Transduction R-HSA-162582 1.152782e-07 6.938 1 0
Activation of BH3-only proteins R-HSA-114452 1.190384e-07 6.924 0 0
Cell Cycle R-HSA-1640170 1.315868e-07 6.881 0 0
Homology Directed Repair R-HSA-5693538 1.553368e-07 6.809 0 0
Chromosome Maintenance R-HSA-73886 1.937430e-07 6.713 0 0
M Phase R-HSA-68886 2.180013e-07 6.662 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 2.238086e-07 6.650 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 2.493947e-07 6.603 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 2.535236e-07 6.596 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 2.766645e-07 6.558 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 2.766645e-07 6.558 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 2.766645e-07 6.558 0 0
SARS-CoV-2-host interactions R-HSA-9705683 3.461441e-07 6.461 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 4.104378e-07 6.387 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 4.241339e-07 6.372 0 0
HCMV Early Events R-HSA-9609690 4.315559e-07 6.365 0 0
Signaling by NOTCH R-HSA-157118 6.036721e-07 6.219 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 8.194375e-07 6.086 0 0
Ub-specific processing proteases R-HSA-5689880 8.648134e-07 6.063 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.100375e-06 5.958 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.210277e-06 5.917 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.456962e-06 5.837 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.893768e-06 5.723 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.904062e-06 5.720 0 0
DNA Replication R-HSA-69306 1.904062e-06 5.720 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.012506e-06 5.696 0 0
Gluconeogenesis R-HSA-70263 2.211117e-06 5.655 0 0
Signaling by VEGF R-HSA-194138 2.265967e-06 5.645 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.752538e-06 5.560 0 0
HCMV Late Events R-HSA-9610379 2.371072e-06 5.625 0 0
Chromatin modifying enzymes R-HSA-3247509 2.676182e-06 5.572 0 0
Protein ubiquitination R-HSA-8852135 2.787609e-06 5.555 0 0
Smooth Muscle Contraction R-HSA-445355 3.855296e-06 5.414 0 0
SARS-CoV-1-host interactions R-HSA-9692914 4.366274e-06 5.360 0 0
Chromatin organization R-HSA-4839726 4.946354e-06 5.306 0 0
HCMV Infection R-HSA-9609646 5.145448e-06 5.289 0 0
Disease R-HSA-1643685 5.521826e-06 5.258 1 0
Regulation of CDH1 Function R-HSA-9764561 5.811811e-06 5.236 0 0
Deubiquitination R-HSA-5688426 6.251195e-06 5.204 0 0
Axon guidance R-HSA-422475 6.517683e-06 5.186 0 0
SARS-CoV-2 Infection R-HSA-9694516 7.216181e-06 5.142 0 0
Cellular Senescence R-HSA-2559583 7.902283e-06 5.102 0 0
Semaphorin interactions R-HSA-373755 1.024451e-05 4.990 0 0
Cell Cycle, Mitotic R-HSA-69278 1.083302e-05 4.965 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.115525e-05 4.953 0 0
Immune System R-HSA-168256 1.460171e-05 4.836 0 0
Developmental Biology R-HSA-1266738 1.546958e-05 4.811 0 0
Nervous system development R-HSA-9675108 1.569324e-05 4.804 0 0
Glycolysis R-HSA-70171 2.240962e-05 4.650 0 0
Programmed Cell Death R-HSA-5357801 2.430419e-05 4.614 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.552308e-05 4.593 0 0
Signaling by WNT R-HSA-195721 2.833568e-05 4.548 0 0
SARS-CoV Infections R-HSA-9679506 2.963247e-05 4.528 0 0
Cell-extracellular matrix interactions R-HSA-446353 4.958897e-05 4.305 0 0
Glucose metabolism R-HSA-70326 7.101135e-05 4.149 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 8.270708e-05 4.082 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.031505e-04 3.987 0 0
Ephrin signaling R-HSA-3928664 1.031505e-04 3.987 0 0
Apoptosis R-HSA-109581 1.141185e-04 3.943 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.199763e-04 3.921 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.489785e-04 3.827 0 0
Muscle contraction R-HSA-397014 1.588526e-04 3.799 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.670102e-04 3.777 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.910353e-04 3.719 0 0
SARS-CoV-1 Infection R-HSA-9678108 1.984087e-04 3.702 0 0
Epigenetic regulation of gene expression R-HSA-212165 2.434981e-04 3.614 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 2.522127e-04 3.598 0 0
Interleukin-12 signaling R-HSA-9020591 2.539988e-04 3.595 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.605747e-04 3.584 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.605747e-04 3.584 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.605747e-04 3.584 0 0
Signaling by RAS mutants R-HSA-6802949 2.605747e-04 3.584 0 0
CASP4 inflammasome assembly R-HSA-9948001 3.507533e-04 3.455 0 0
Signaling by Interleukins R-HSA-449147 3.777184e-04 3.423 0 0
L1CAM interactions R-HSA-373760 4.279366e-04 3.369 0 0
Manipulation of host energy metabolism R-HSA-9636667 4.601984e-04 3.337 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.029210e-04 3.299 0 0
Interleukin-12 family signaling R-HSA-447115 5.119424e-04 3.291 0 0
DNA Repair R-HSA-73894 6.024444e-04 3.220 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 7.612051e-04 3.118 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 8.761052e-04 3.057 1 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 8.910057e-04 3.050 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 8.910057e-04 3.050 0 0
Non-canonical inflammasome activation R-HSA-9686114 8.968547e-04 3.047 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 9.866983e-04 3.006 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.007198e-03 2.997 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.046927e-03 2.980 0 0
Protein methylation R-HSA-8876725 1.046927e-03 2.980 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.069341e-03 2.971 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 1.143398e-03 2.942 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.169873e-03 2.932 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.587100e-03 2.799 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.420290e-03 2.848 0 0
Membrane Trafficking R-HSA-199991 1.521702e-03 2.818 0 0
Generic Transcription Pathway R-HSA-212436 1.373605e-03 2.862 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 1.423607e-03 2.847 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.605418e-03 2.794 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.613541e-03 2.792 0 0
MAP2K and MAPK activation R-HSA-5674135 1.729752e-03 2.762 0 0
Centrosome maturation R-HSA-380287 1.763994e-03 2.754 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.948391e-03 2.710 0 0
Vesicle-mediated transport R-HSA-5653656 2.247950e-03 2.648 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.280424e-03 2.642 0 0
RNA Polymerase II Transcription R-HSA-73857 2.518877e-03 2.599 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 2.743217e-03 2.562 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.872156e-03 2.542 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 3.432018e-03 2.464 0 0
Syndecan interactions R-HSA-3000170 3.454994e-03 2.462 0 0
Gene expression (Transcription) R-HSA-74160 3.509904e-03 2.455 0 0
Platelet activation, signaling and aggregation R-HSA-76002 3.536180e-03 2.451 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 3.566303e-03 2.448 0 0
Leishmania infection R-HSA-9658195 4.115667e-03 2.386 0 0
Parasitic Infection Pathways R-HSA-9824443 4.115667e-03 2.386 0 0
Sema4D in semaphorin signaling R-HSA-400685 4.157925e-03 2.381 0 0
CHL1 interactions R-HSA-447041 4.878592e-03 2.312 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 4.878592e-03 2.312 0 0
Interaction between L1 and Ankyrins R-HSA-445095 4.941719e-03 2.306 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.941719e-03 2.306 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 5.793135e-03 2.237 0 0
FOXO-mediated transcription R-HSA-9614085 5.793135e-03 2.237 0 0
Formation of annular gap junctions R-HSA-196025 5.863729e-03 2.232 0 0
Cilium Assembly R-HSA-5617833 6.101245e-03 2.215 0 0
Adaptive Immune System R-HSA-1280218 6.701023e-03 2.174 0 0
Gap junction degradation R-HSA-190873 6.931822e-03 2.159 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 6.931822e-03 2.159 0 0
Response of endothelial cells to shear stress R-HSA-9860931 6.948404e-03 2.158 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 8.081098e-03 2.093 0 0
Organelle biogenesis and maintenance R-HSA-1852241 8.825138e-03 2.054 0 0
eNOS activation R-HSA-203615 8.931622e-03 2.049 0 0
PECAM1 interactions R-HSA-210990 9.309812e-03 2.031 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 9.601423e-03 2.018 1 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 9.637927e-03 2.016 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.003935e-02 1.998 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.005024e-02 1.998 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.019454e-02 1.992 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.019454e-02 1.992 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.019454e-02 1.992 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.019454e-02 1.992 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.019454e-02 1.992 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.019454e-02 1.992 0 0
Extracellular matrix organization R-HSA-1474244 1.070023e-02 1.971 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 1.146506e-02 1.941 0 0
Scavenging by Class F Receptors R-HSA-3000484 1.199870e-02 1.921 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 1.215644e-02 1.915 0 0
G alpha (12/13) signalling events R-HSA-416482 1.228318e-02 1.911 0 0
PKR-mediated signaling R-HSA-9833482 1.325832e-02 1.878 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.825585e-02 1.739 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 1.498506e-02 1.824 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.999395e-02 1.699 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.493147e-02 1.826 1 1
Platelet degranulation R-HSA-114608 1.604810e-02 1.795 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.683805e-02 1.774 1 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.929937e-02 1.714 0 0
Signal regulatory protein family interactions R-HSA-391160 1.498506e-02 1.824 0 0
G2/M Transition R-HSA-69275 1.970191e-02 1.705 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.515777e-02 1.819 0 0
Mitotic G2-G2/M phases R-HSA-453274 2.054458e-02 1.687 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.179846e-02 1.662 0 0
Uptake and function of anthrax toxins R-HSA-5210891 2.179846e-02 1.662 0 0
Signaling by Hippo R-HSA-2028269 2.179846e-02 1.662 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 2.230278e-02 1.652 0 0
Mitotic Prometaphase R-HSA-68877 2.275771e-02 1.643 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.321886e-02 1.634 0 0
Parasite infection R-HSA-9664407 2.351335e-02 1.629 0 0
Leishmania phagocytosis R-HSA-9664417 2.351335e-02 1.629 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 2.351335e-02 1.629 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 2.559682e-02 1.592 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.560065e-02 1.592 0 0
Rap1 signalling R-HSA-392517 2.560065e-02 1.592 0 0
The NLRP3 inflammasome R-HSA-844456 2.560065e-02 1.592 0 0
Bacterial Infection Pathways R-HSA-9824439 2.658113e-02 1.575 0 0
Signal transduction by L1 R-HSA-445144 2.759537e-02 1.559 0 0
Nephrin family interactions R-HSA-373753 2.759537e-02 1.559 0 0
NRAGE signals death through JNK R-HSA-193648 2.868453e-02 1.542 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.868453e-02 1.542 0 0
mRNA Splicing R-HSA-72172 2.871111e-02 1.542 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.965056e-02 1.528 0 0
Potential therapeutics for SARS R-HSA-9679191 3.021640e-02 1.520 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 3.027473e-02 1.519 0 0
RSV-host interactions R-HSA-9833110 3.223045e-02 1.492 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 3.292349e-02 1.482 0 0
Death Receptor Signaling R-HSA-73887 3.292349e-02 1.482 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 3.379530e-02 1.471 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 3.393671e-02 1.469 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.393671e-02 1.469 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 3.535443e-02 1.452 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.579254e-02 1.446 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 3.592370e-02 1.445 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 3.616488e-02 1.442 0 0
MAPK family signaling cascades R-HSA-5683057 3.631205e-02 1.440 1 0
Innate Immune System R-HSA-168249 3.635838e-02 1.439 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.016246e-02 1.396 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.016246e-02 1.396 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.016246e-02 1.396 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.016246e-02 1.396 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.016246e-02 1.396 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.016246e-02 1.396 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.016246e-02 1.396 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.016246e-02 1.396 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.016246e-02 1.396 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.016246e-02 1.396 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.016246e-02 1.396 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 4.016246e-02 1.396 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 4.016246e-02 1.396 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 4.078464e-02 1.390 0 0
MET activates PTK2 signaling R-HSA-8874081 4.317356e-02 1.365 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 4.401171e-02 1.356 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 4.460932e-02 1.351 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.561346e-02 1.341 0 0
Inflammasomes R-HSA-622312 4.810305e-02 1.318 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 4.986461e-02 1.302 0 0
Axonal growth stimulation R-HSA-209563 4.994998e-02 1.301 0 0
STAT6-mediated induction of chemokines R-HSA-3249367 4.994998e-02 1.301 0 0
MET interacts with TNS proteins R-HSA-8875513 4.994998e-02 1.301 0 0
Histamine receptors R-HSA-390650 4.994998e-02 1.301 0 0
Signaling by NOTCH4 R-HSA-9013694 5.292634e-02 1.276 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 5.322632e-02 1.274 0 0
Interleukin-37 signaling R-HSA-9008059 5.322632e-02 1.274 0 0
Molecules associated with elastic fibres R-HSA-2129379 5.585756e-02 1.253 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 6.922840e-02 1.160 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 7.872129e-02 1.104 0 0
Regulation of PTEN localization R-HSA-8948747 9.741933e-02 1.011 0 0
Recycling of eIF2:GDP R-HSA-72731 9.741933e-02 1.011 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 9.741933e-02 1.011 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.066264e-01 0.972 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.066264e-01 0.972 0 0
Lipophagy R-HSA-9613354 1.157401e-01 0.937 0 0
Striated Muscle Contraction R-HSA-390522 6.401541e-02 1.194 0 0
RAF activation R-HSA-5673000 6.681888e-02 1.175 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.157401e-01 0.937 0 0
Integrin signaling R-HSA-354192 6.125327e-02 1.213 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 1.066264e-01 0.972 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.032956e-01 0.986 0 0
PTK6 Expression R-HSA-8849473 9.741933e-02 1.011 0 0
Calcineurin activates NFAT R-HSA-2025928 1.157401e-01 0.937 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 9.373170e-02 1.028 0 0
Eukaryotic Translation Elongation R-HSA-156842 8.820603e-02 1.055 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 7.872129e-02 1.104 0 0
Neutrophil degranulation R-HSA-6798695 5.877346e-02 1.231 0 0
DAG and IP3 signaling R-HSA-1489509 1.032956e-01 0.986 0 0
Cam-PDE 1 activation R-HSA-111957 7.872129e-02 1.104 0 0
p75NTR regulates axonogenesis R-HSA-193697 1.157401e-01 0.937 0 0
MET promotes cell motility R-HSA-8875878 7.842405e-02 1.106 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.157401e-01 0.937 0 0
GPVI-mediated activation cascade R-HSA-114604 7.254539e-02 1.139 0 0
NADE modulates death signalling R-HSA-205025 5.963829e-02 1.224 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 1.066264e-01 0.972 0 0
ARMS-mediated activation R-HSA-170984 1.157401e-01 0.937 0 0
Developmental Cell Lineages R-HSA-9734767 7.239939e-02 1.140 0 0
Clathrin-mediated endocytosis R-HSA-8856828 8.483241e-02 1.071 0 0
Late Phase of HIV Life Cycle R-HSA-162599 8.337270e-02 1.079 0 0
Co-inhibition by BTLA R-HSA-9927353 6.922840e-02 1.160 0 0
Autophagy R-HSA-9612973 1.049224e-01 0.979 0 0
Recycling pathway of L1 R-HSA-437239 1.098138e-01 0.959 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 1.065411e-01 0.972 0 0
Metabolism of RNA R-HSA-8953854 1.022693e-01 0.990 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 7.872129e-02 1.104 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 7.872129e-02 1.104 0 0
Nef and signal transduction R-HSA-164944 8.811794e-02 1.055 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 1.157401e-01 0.937 0 0
Gap junction trafficking R-HSA-190828 1.000782e-01 1.000 0 0
Elastic fibre formation R-HSA-1566948 7.842405e-02 1.106 0 0
HIV Life Cycle R-HSA-162587 1.065510e-01 0.972 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.157401e-01 0.937 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 6.125327e-02 1.213 0 0
Gap junction trafficking and regulation R-HSA-157858 1.164376e-01 0.934 0 0
Sensory processing of sound R-HSA-9659379 6.096610e-02 1.215 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.017820e-02 1.045 0 0
HIV Infection R-HSA-162906 1.114365e-01 0.953 0 0
Hemostasis R-HSA-109582 7.131446e-02 1.147 0 0
Regulation of necroptotic cell death R-HSA-5675482 6.125327e-02 1.213 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 7.842405e-02 1.106 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 1.065411e-01 0.972 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 1.065411e-01 0.972 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.087315e-01 0.964 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 1.003112e-01 0.999 0 0
TBC/RABGAPs R-HSA-8854214 9.688998e-02 1.014 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.688998e-02 1.014 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 8.431771e-02 1.074 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.131130e-01 0.946 0 0
Signaling by SCF-KIT R-HSA-1433557 9.688998e-02 1.014 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 9.688998e-02 1.014 0 0
Interferon Signaling R-HSA-913531 1.230761e-01 0.910 0 0
The phototransduction cascade R-HSA-2514856 1.231600e-01 0.910 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.240950e-01 0.906 0 0
Signaling by ALK in cancer R-HSA-9700206 1.240950e-01 0.906 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 1.247614e-01 0.904 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.247614e-01 0.904 0 0
Regulation of CDH11 function R-HSA-9762292 1.247614e-01 0.904 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.247614e-01 0.904 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.247614e-01 0.904 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.336913e-01 0.874 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.336913e-01 0.874 0 0
vRNP Assembly R-HSA-192905 1.336913e-01 0.874 0 0
Dissolution of Fibrin Clot R-HSA-75205 1.336913e-01 0.874 0 0
Inositol phosphate metabolism R-HSA-1483249 1.355234e-01 0.868 0 0
Ion homeostasis R-HSA-5578775 1.403541e-01 0.853 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.425305e-01 0.846 0 0
Sodium/Calcium exchangers R-HSA-425561 1.425305e-01 0.846 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.438532e-01 0.842 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.438532e-01 0.842 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 1.512801e-01 0.820 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 1.512801e-01 0.820 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.512801e-01 0.820 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.512801e-01 0.820 0 0
Regulation of IFNG signaling R-HSA-877312 1.512801e-01 0.820 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.512801e-01 0.820 0 0
Pervasive developmental disorders R-HSA-9005895 1.512801e-01 0.820 0 0
Disorders of Nervous System Development R-HSA-9697154 1.512801e-01 0.820 0 0
Rab regulation of trafficking R-HSA-9007101 1.521010e-01 0.818 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.544574e-01 0.811 0 0
RAB geranylgeranylation R-HSA-8873719 1.544574e-01 0.811 0 0
PLC beta mediated events R-HSA-112043 1.580254e-01 0.801 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.599410e-01 0.796 0 0
Frs2-mediated activation R-HSA-170968 1.599410e-01 0.796 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 1.599410e-01 0.796 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.599410e-01 0.796 0 0
NCAM signaling for neurite out-growth R-HSA-375165 1.616089e-01 0.792 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.685140e-01 0.773 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.685140e-01 0.773 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 1.685140e-01 0.773 0 0
Regulation of KIT signaling R-HSA-1433559 1.685140e-01 0.773 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.688196e-01 0.773 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.691154e-01 0.772 1 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 1.768161e-01 0.752 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.770001e-01 0.752 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.770001e-01 0.752 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.770001e-01 0.752 0 0
DCC mediated attractive signaling R-HSA-418885 1.770001e-01 0.752 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.770001e-01 0.752 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.770001e-01 0.752 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 1.770001e-01 0.752 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.770001e-01 0.752 0 0
Other semaphorin interactions R-HSA-416700 1.770001e-01 0.752 0 0
G-protein mediated events R-HSA-112040 1.797351e-01 0.745 0 0
Regulated Necrosis R-HSA-5218859 1.833976e-01 0.737 0 0
Prolonged ERK activation events R-HSA-169893 1.854000e-01 0.732 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.854000e-01 0.732 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.870710e-01 0.728 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 1.937148e-01 0.713 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 1.937148e-01 0.713 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 1.937148e-01 0.713 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 1.937148e-01 0.713 0 0
Fibronectin matrix formation R-HSA-1566977 1.937148e-01 0.713 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 1.937148e-01 0.713 0 0
Disorders of Developmental Biology R-HSA-9675151 1.937148e-01 0.713 0 0
ECM proteoglycans R-HSA-3000178 1.944484e-01 0.711 0 0
Metabolism of cofactors R-HSA-8978934 1.944484e-01 0.711 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 1.945128e-01 0.711 0 0
Post-translational protein modification R-HSA-597592 1.983388e-01 0.703 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.018625e-01 0.695 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.019452e-01 0.695 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.019452e-01 0.695 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 2.019452e-01 0.695 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.100920e-01 0.678 0 0
PKA activation R-HSA-163615 2.100920e-01 0.678 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.100920e-01 0.678 0 0
Platelet sensitization by LDL R-HSA-432142 2.100920e-01 0.678 0 0
PTEN Regulation R-HSA-6807070 2.157349e-01 0.666 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.181562e-01 0.661 0 0
Other interleukin signaling R-HSA-449836 2.181562e-01 0.661 0 0
Nuclear Receptor transcription pathway R-HSA-383280 2.205297e-01 0.657 0 0
Integrin cell surface interactions R-HSA-216083 2.205297e-01 0.657 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 2.261386e-01 0.646 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.261386e-01 0.646 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.261386e-01 0.646 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.261386e-01 0.646 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 2.261386e-01 0.646 0 0
Signaling by MET R-HSA-6806834 2.280383e-01 0.642 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.340400e-01 0.631 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.340400e-01 0.631 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 2.340400e-01 0.631 0 0
Basigin interactions R-HSA-210991 2.340400e-01 0.631 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.355648e-01 0.628 0 0
Visual phototransduction R-HSA-2187338 2.398946e-01 0.620 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.418611e-01 0.616 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.418611e-01 0.616 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.418611e-01 0.616 0 0
Attachment and Entry R-HSA-9694614 2.418611e-01 0.616 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.418611e-01 0.616 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.418611e-01 0.616 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.418611e-01 0.616 0 0
FGFR2 alternative splicing R-HSA-6803529 2.496029e-01 0.603 0 0
mTORC1-mediated signalling R-HSA-166208 2.496029e-01 0.603 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.506561e-01 0.601 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.506561e-01 0.601 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 2.572661e-01 0.590 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 2.572661e-01 0.590 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.572661e-01 0.590 0 0
Formation of the ureteric bud R-HSA-9830674 2.572661e-01 0.590 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.572661e-01 0.590 0 0
Growth hormone receptor signaling R-HSA-982772 2.572661e-01 0.590 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 2.572661e-01 0.590 0 0
Selective autophagy R-HSA-9663891 2.619944e-01 0.582 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.648516e-01 0.577 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.648516e-01 0.577 0 0
Mitochondrial RNA degradation R-HSA-9836573 2.648516e-01 0.577 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.648516e-01 0.577 0 0
Neurodegenerative Diseases R-HSA-8863678 2.648516e-01 0.577 0 0
Downstream TCR signaling R-HSA-202424 2.695563e-01 0.569 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 2.699938e-01 0.569 0 0
Cell surface interactions at the vascular wall R-HSA-202733 2.706219e-01 0.568 0 0
Long-term potentiation R-HSA-9620244 2.723600e-01 0.565 0 0
Laminin interactions R-HSA-3000157 2.723600e-01 0.565 0 0
Tight junction interactions R-HSA-420029 2.723600e-01 0.565 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 2.723600e-01 0.565 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 2.723600e-01 0.565 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 2.723600e-01 0.565 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 2.723600e-01 0.565 0 0
Signaling by TGFB family members R-HSA-9006936 2.755162e-01 0.560 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.797922e-01 0.553 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.797922e-01 0.553 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 2.797922e-01 0.553 0 0
Metabolism of proteins R-HSA-392499 2.800385e-01 0.553 0 0
Protein folding R-HSA-391251 2.808958e-01 0.551 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 2.871489e-01 0.542 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 2.871489e-01 0.542 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 2.871489e-01 0.542 0 0
Cristae formation R-HSA-8949613 2.871489e-01 0.542 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.871489e-01 0.542 0 0
Mitochondrial protein degradation R-HSA-9837999 2.884489e-01 0.540 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.922224e-01 0.534 0 0
HIV elongation arrest and recovery R-HSA-167287 2.944309e-01 0.531 0 0
Pausing and recovery of HIV elongation R-HSA-167290 2.944309e-01 0.531 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 2.944309e-01 0.531 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 2.944309e-01 0.531 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 2.944309e-01 0.531 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.997615e-01 0.523 0 0
Late endosomal microautophagy R-HSA-9615710 3.016390e-01 0.521 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.016390e-01 0.521 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.016390e-01 0.521 0 0
DARPP-32 events R-HSA-180024 3.016390e-01 0.521 0 0
Platelet calcium homeostasis R-HSA-418360 3.016390e-01 0.521 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 3.087739e-01 0.510 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.087739e-01 0.510 0 0
DAP12 signaling R-HSA-2424491 3.087739e-01 0.510 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 3.087739e-01 0.510 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.087739e-01 0.510 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 3.144265e-01 0.502 0 0
Leishmania parasite growth and survival R-HSA-9664433 3.144265e-01 0.502 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.147990e-01 0.502 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.158363e-01 0.501 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.158363e-01 0.501 0 0
Downstream signal transduction R-HSA-186763 3.158363e-01 0.501 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 3.158363e-01 0.501 0 0
Budding and maturation of HIV virion R-HSA-162588 3.158363e-01 0.501 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 3.158363e-01 0.501 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.158363e-01 0.501 0 0
PI Metabolism R-HSA-1483255 3.222923e-01 0.492 0 0
HS-GAG degradation R-HSA-2024096 3.228271e-01 0.491 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 3.228271e-01 0.491 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 3.297468e-01 0.482 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.297468e-01 0.482 0 0
G-protein beta:gamma signalling R-HSA-397795 3.297468e-01 0.482 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 3.297468e-01 0.482 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.297468e-01 0.482 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.297468e-01 0.482 0 0
Opioid Signalling R-HSA-111885 3.297655e-01 0.482 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.365962e-01 0.473 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.365962e-01 0.473 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.365962e-01 0.473 0 0
Platelet homeostasis R-HSA-418346 3.409328e-01 0.467 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 3.433760e-01 0.464 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.433760e-01 0.464 0 0
Nuclear import of Rev protein R-HSA-180746 3.433760e-01 0.464 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.500870e-01 0.456 0 0
Signalling to ERKs R-HSA-187687 3.500870e-01 0.456 0 0
PERK regulates gene expression R-HSA-381042 3.500870e-01 0.456 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.520425e-01 0.453 0 0
TCR signaling R-HSA-202403 3.557318e-01 0.449 0 0
HS-GAG biosynthesis R-HSA-2022928 3.567298e-01 0.448 0 0
CaM pathway R-HSA-111997 3.567298e-01 0.448 0 0
Calmodulin induced events R-HSA-111933 3.567298e-01 0.448 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.567298e-01 0.448 0 0
FLT3 signaling in disease R-HSA-9682385 3.567298e-01 0.448 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 3.567298e-01 0.448 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 3.633051e-01 0.440 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.633051e-01 0.440 0 0
Ovarian tumor domain proteases R-HSA-5689896 3.633051e-01 0.440 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.698136e-01 0.432 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.762560e-01 0.425 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.762560e-01 0.425 0 0
RAS processing R-HSA-9648002 3.762560e-01 0.425 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.762560e-01 0.425 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 3.762560e-01 0.425 0 0
Signaling by ALK R-HSA-201556 3.762560e-01 0.425 0 0
Interferon alpha/beta signaling R-HSA-909733 3.813374e-01 0.419 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 3.813374e-01 0.419 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.826329e-01 0.417 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.826329e-01 0.417 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.826329e-01 0.417 0 0
HIV Transcription Elongation R-HSA-167169 3.826329e-01 0.417 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.826329e-01 0.417 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.826329e-01 0.417 0 0
Generation of second messenger molecules R-HSA-202433 3.826329e-01 0.417 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 3.826329e-01 0.417 0 0
Aggrephagy R-HSA-9646399 3.826329e-01 0.417 0 0
Glycogen metabolism R-HSA-8982491 3.826329e-01 0.417 0 0
Interleukin-2 family signaling R-HSA-451927 3.826329e-01 0.417 0 0
Mitochondrial biogenesis R-HSA-1592230 3.885763e-01 0.411 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 3.889450e-01 0.410 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 3.889450e-01 0.410 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 3.889450e-01 0.410 0 0
PKMTs methylate histone lysines R-HSA-3214841 3.889450e-01 0.410 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.921819e-01 0.407 1 0
Negative regulation of MAPK pathway R-HSA-5675221 3.951930e-01 0.403 0 0
Infection with Enterobacteria R-HSA-9640148 3.977547e-01 0.400 0 0
Ca-dependent events R-HSA-111996 4.013774e-01 0.396 0 0
MTOR signalling R-HSA-165159 4.013774e-01 0.396 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.029413e-01 0.395 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 4.029413e-01 0.395 0 0
PIP3 activates AKT signaling R-HSA-1257604 4.041275e-01 0.393 1 1
Netrin-1 signaling R-HSA-373752 4.135584e-01 0.383 0 0
DAP12 interactions R-HSA-2172127 4.135584e-01 0.383 0 0
Methylation R-HSA-156581 4.135584e-01 0.383 0 0
Amine ligand-binding receptors R-HSA-375280 4.135584e-01 0.383 0 0
Host Interactions of HIV factors R-HSA-162909 4.136106e-01 0.383 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 4.195561e-01 0.377 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 4.195561e-01 0.377 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.195561e-01 0.377 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 4.195561e-01 0.377 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.254929e-01 0.371 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.254929e-01 0.371 0 0
Apoptotic execution phase R-HSA-75153 4.254929e-01 0.371 0 0
Mitotic Anaphase R-HSA-68882 4.358373e-01 0.361 0 0
GPER1 signaling R-HSA-9634597 4.371861e-01 0.359 0 0
Metal ion SLC transporters R-HSA-425410 4.371861e-01 0.359 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 4.381317e-01 0.358 1 0
Mitotic Metaphase and Anaphase R-HSA-2555396 4.385256e-01 0.358 0 0
Degradation of CDH1 R-HSA-9766229 4.429436e-01 0.354 0 0
Cardiac conduction R-HSA-5576891 4.450363e-01 0.352 0 0
Azathioprine ADME R-HSA-9748787 4.486426e-01 0.348 0 0
Complex IV assembly R-HSA-9864848 4.542837e-01 0.343 0 0
mRNA 3'-end processing R-HSA-72187 4.598673e-01 0.337 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.598673e-01 0.337 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.598673e-01 0.337 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.653942e-01 0.332 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.653942e-01 0.332 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.653942e-01 0.332 0 0
Nucleotide biosynthesis R-HSA-8956320 4.653942e-01 0.332 0 0
Translation initiation complex formation R-HSA-72649 4.708649e-01 0.327 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 4.816399e-01 0.317 0 0
Macroautophagy R-HSA-1632852 4.821483e-01 0.317 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 4.921967e-01 0.308 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 4.921967e-01 0.308 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 4.973948e-01 0.303 0 0
snRNP Assembly R-HSA-191859 4.973948e-01 0.303 0 0
Metabolism of non-coding RNA R-HSA-194441 4.973948e-01 0.303 0 0
Signaling by ERBB2 R-HSA-1227986 5.025399e-01 0.299 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.049630e-01 0.297 0 0
Viral Messenger RNA Synthesis R-HSA-168325 5.076327e-01 0.294 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.076327e-01 0.294 0 0
Aquaporin-mediated transport R-HSA-445717 5.076327e-01 0.294 0 0
Signaling by PDGF R-HSA-186797 5.126736e-01 0.290 0 0
tRNA processing in the nucleus R-HSA-6784531 5.126736e-01 0.290 0 0
Mitochondrial protein import R-HSA-1268020 5.126736e-01 0.290 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.126736e-01 0.290 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 5.145413e-01 0.289 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 5.176632e-01 0.286 0 0
Signaling by PTK6 R-HSA-8848021 5.176632e-01 0.286 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 5.208591e-01 0.283 0 0
Interleukin-1 family signaling R-HSA-446652 5.208591e-01 0.283 0 0
CD22 mediated BCR regulation R-HSA-5690714 5.226021e-01 0.282 0 0
Ion transport by P-type ATPases R-HSA-936837 5.226021e-01 0.282 0 0
Protein localization R-HSA-9609507 5.239975e-01 0.281 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 5.302332e-01 0.276 0 0
Kidney development R-HSA-9830369 5.371191e-01 0.270 0 0
Transcription of the HIV genome R-HSA-167172 5.418599e-01 0.266 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.511973e-01 0.259 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.511973e-01 0.259 0 0
COPII-mediated vesicle transport R-HSA-204005 5.511973e-01 0.259 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 5.557948e-01 0.255 0 0
Retinoid metabolism and transport R-HSA-975634 5.557948e-01 0.255 0 0
Separation of Sister Chromatids R-HSA-2467813 5.576049e-01 0.254 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 5.603455e-01 0.252 0 0
Ca2+ pathway R-HSA-4086398 5.648498e-01 0.248 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 5.693083e-01 0.245 0 0
GPCR downstream signalling R-HSA-388396 5.712126e-01 0.243 0 0
ISG15 antiviral mechanism R-HSA-1169408 5.737213e-01 0.241 0 0
UCH proteinases R-HSA-5689603 5.780894e-01 0.238 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 5.781045e-01 0.238 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 5.809761e-01 0.236 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 5.866926e-01 0.232 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 5.951215e-01 0.225 0 0
Signaling by FGFR2 R-HSA-5654738 5.951215e-01 0.225 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 5.951215e-01 0.225 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 5.992716e-01 0.222 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 5.992716e-01 0.222 0 0
Influenza Infection R-HSA-168255 6.034350e-01 0.219 0 0
Cytoprotection by HMOX1 R-HSA-9707564 6.074454e-01 0.216 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.114699e-01 0.214 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 6.193964e-01 0.208 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 6.193964e-01 0.208 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.232991e-01 0.205 0 0
Post NMDA receptor activation events R-HSA-438064 6.271621e-01 0.203 0 0
Chaperonin-mediated protein folding R-HSA-390466 6.271621e-01 0.203 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 6.276083e-01 0.202 0 0
Peptide chain elongation R-HSA-156902 6.309857e-01 0.200 0 0
Neurotransmitter release cycle R-HSA-112310 6.385163e-01 0.195 0 0
FCGR activation R-HSA-2029481 6.531224e-01 0.185 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 6.566813e-01 0.183 1 1
Transport to the Golgi and subsequent modification R-HSA-948021 6.629282e-01 0.179 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.671417e-01 0.176 0 0
Regulation of insulin secretion R-HSA-422356 6.739387e-01 0.171 0 0
Signaling by FGFR R-HSA-190236 6.739387e-01 0.171 1 0
Translation R-HSA-72766 6.797845e-01 0.168 0 0
ABC-family proteins mediated transport R-HSA-382556 6.805977e-01 0.167 0 0
Signaling by GPCR R-HSA-372790 6.822685e-01 0.166 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.871215e-01 0.163 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 6.935129e-01 0.159 0 0
Nucleotide Excision Repair R-HSA-5696398 6.997745e-01 0.155 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 7.089292e-01 0.149 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 7.089292e-01 0.149 0 0
Stimuli-sensing channels R-HSA-2672351 7.089292e-01 0.149 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.207053e-01 0.142 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.207053e-01 0.142 0 0
FCERI mediated MAPK activation R-HSA-2871796 7.207053e-01 0.142 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 7.254882e-01 0.139 0 0
rRNA processing R-HSA-72312 7.315776e-01 0.136 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.374873e-01 0.132 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.374873e-01 0.132 0 0
Metabolism of vitamins and cofactors R-HSA-196854 7.556944e-01 0.122 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 7.558033e-01 0.122 1 1
Signaling by NTRK1 (TRKA) R-HSA-187037 7.704879e-01 0.113 0 0
Circadian clock R-HSA-9909396 7.820522e-01 0.107 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 7.930371e-01 0.101 0 0
Integration of energy metabolism R-HSA-163685 7.930371e-01 0.101 0 0
Unfolded Protein Response (UPR) R-HSA-381119 7.993620e-01 0.097 0 0
Signaling by NTRKs R-HSA-166520 8.190896e-01 0.087 0 0
MITF-M-dependent gene expression R-HSA-9856651 8.227973e-01 0.085 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.264295e-01 0.083 0 0
Phospholipid metabolism R-HSA-1483257 8.351765e-01 0.078 0 0
Cellular response to starvation R-HSA-9711097 8.368880e-01 0.077 0 0
Interferon gamma signaling R-HSA-877300 8.385691e-01 0.076 0 0
Regulation of TP53 Activity R-HSA-5633007 8.402331e-01 0.076 0 0
SLC transporter disorders R-HSA-5619102 8.514127e-01 0.070 0 0
tRNA processing R-HSA-72306 8.574483e-01 0.067 0 0
G alpha (s) signalling events R-HSA-418555 8.589187e-01 0.066 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 8.646511e-01 0.063 0 0
Transmission across Chemical Synapses R-HSA-112315 8.684573e-01 0.061 0 0
Respiratory electron transport R-HSA-611105 8.687980e-01 0.061 0 0
Diseases of glycosylation R-HSA-3781865 8.767166e-01 0.057 0 0
Ion channel transport R-HSA-983712 8.829512e-01 0.054 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 8.864886e-01 0.052 0 0
Glycosaminoglycan metabolism R-HSA-1630316 8.877124e-01 0.052 0 0
Signaling by ROBO receptors R-HSA-376176 8.987899e-01 0.046 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 9.087806e-01 0.042 0 0
Drug ADME R-HSA-9748784 9.142978e-01 0.039 0 0
Metabolism of nucleotides R-HSA-15869 9.289370e-01 0.032 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.311226e-01 0.031 0 0
G alpha (i) signalling events R-HSA-418594 9.353746e-01 0.029 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.366297e-01 0.028 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.431906e-01 0.025 0 0
G alpha (q) signalling events R-HSA-416476 9.469215e-01 0.024 0 0
Cellular response to chemical stress R-HSA-9711123 9.490908e-01 0.023 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.541360e-01 0.020 0 0
Neuronal System R-HSA-112316 9.619525e-01 0.017 0 0
Biological oxidations R-HSA-211859 9.766718e-01 0.010 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.865405e-01 0.006 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.869586e-01 0.006 0 0
Diseases of metabolism R-HSA-5668914 9.904910e-01 0.004 0 0
Sensory Perception R-HSA-9709957 9.906806e-01 0.004 0 0
Transport of small molecules R-HSA-382551 9.982187e-01 0.001 0 0
GPCR ligand binding R-HSA-500792 9.982910e-01 0.001 0 0
Metabolism R-HSA-1430728 9.999147e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 9.999984e-01 0.000 0 0
PI3K Cascade R-HSA-109704 1.000000e+00 0.000 1 1
IRS-mediated signalling R-HSA-112399 1.000000e+00 0.000 1 0
Signaling by FGFR in disease R-HSA-1226099 1.000000e+00 0.000 1 0
betaKlotho-mediated ligand binding R-HSA-1307965 1.000000e+00 0.000 1 1
FGFR4 mutant receptor activation R-HSA-1839128 1.000000e+00 0.000 1 1
FGFR4 ligand binding and activation R-HSA-190322 1.000000e+00 0.000 1 1
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 1.000000e+00 0.000 1 0
IGF1R signaling cascade R-HSA-2428924 1.000000e+00 0.000 1 0
IRS-related events triggered by IGF1R R-HSA-2428928 1.000000e+00 0.000 1 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 1.000000e+00 0.000 1 1
FRS-mediated FGFR4 signaling R-HSA-5654712 1.000000e+00 0.000 1 1
Downstream signaling of activated FGFR4 R-HSA-5654716 1.000000e+00 0.000 1 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 1.000000e+00 0.000 1 1
PI-3K cascade:FGFR4 R-HSA-5654720 1.000000e+00 0.000 1 1
Negative regulation of FGFR4 signaling R-HSA-5654733 1.000000e+00 0.000 1 1
Signaling by FGFR4 R-HSA-5654743 1.000000e+00 0.000 1 0
Signaling by FGFR4 in disease R-HSA-5655291 1.000000e+00 0.000 1 1
Insulin receptor signalling cascade R-HSA-74751 1.000000e+00 0.000 1 0
Signaling by Insulin receptor R-HSA-74752 1.000000e+00 0.000 1 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways