ERK1

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included

S Sites Probabilities

T Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Sites with acceptor types representing >8% and count ≥10 are included

Download Data Table

Motif clusters with count ≥ 10 are shown

Download

substrate_uniprot	site	source	substrate_genes	site_seq
A0MZ66	T537	Sugiyama	SHTN1 KIAA1598	TKTALNKKTLEAEFNsPsPPtPEPGEGPRKLEGCTSSKVTF
A5A3E0	T949	Sugiyama	POTEF A26C1B	TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A6NKT7	T1475	Sugiyama	RGPD3 RGP3	DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
A6NMY6	S22	Sugiyama	ANXA2P2 ANX2L2 ANX2P2 LPC2B	stVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNI
C9JLW8	S21	SIGNOR\|EPSD\|PSP	MCRIP1 FAM195B GRAN2	MtssPVSRVVYNGKRtssPRsPPsssEIFtPAHEENVRFIy
C9JLW8	T30	SIGNOR\|EPSD\|PSP	MCRIP1 FAM195B GRAN2	VYNGKRtssPRsPPsssEIFtPAHEENVRFIyEAWQGVERD
O00115	S70	Sugiyama	DNASE2 DNASE2A DNL2	QYKyLDEssGGWRDGRALINsPEGAVGRSLQPLyRSNTSQL
O00151	S90	Sugiyama	PDLIM1 CLIM1 CLP36	IKGCTDNLtLtVARsEHKVWsPLVtEEGKRHPYKMNLASEP
O00170	T162	Sugiyama	AIP XAP2	QQNPQPLIFHMEMLKVEsPGtYQQDPWAMTDEEKAKAVPLI
O00213	S175	SIGNOR	APBB1 FE65 RIR	GEAEEEEEDDDDEEEEEDLSsPPGLPEPLESVEAPPRPQAL
O00213	S287	SIGNOR	APBB1 FE65 RIR	GTYYWHIPTGTTQWEPPGRAsPsQGSSPQEESQLTWTGFAH
O00213	S347	SIGNOR	APBB1 FE65 RIR	MELGLKEPEEGTLTFPAQSLsPEPLPQEEEKLPPRNTNPGI
O00213	T709	SIGNOR	APBB1 FE65 RIR	VRRGVQSLWGSLKPKRLGAHtP___________________
O00232	S335	Sugiyama	PSMD12	MRWSTLVEDYGMELRKGsLEsPAtDVFGsTEEGEKRWKDLK
O00410	S974	Sugiyama	IPO5 KPNB3 RANBP5	VIQSADSKTKENVNAtENCIsAVGKIMKFKPDCVNVEEVLP
O00429	S126	Sugiyama	DNM1L DLP1 DRP1	EIRQEIENETERISGNNKGVsPEPIHLKIFSPNVVNLTLVD
O00429	S616	SIGNOR\|EPSD\|PSP	DNM1L DLP1 DRP1	SKAEELLAEEKsKPIPIMPAsPQKGHAVNLLDVPVPVARKL
O00571	S70	Sugiyama	DDX3X DBX DDX3	KGFyDKDSSGWsssKDKDAyssFGsRsDsRGKssFFsDRGs
O14497	S363	Sugiyama	ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1	AAAAAAASGGAQQRsHHAPMsPGssGGGGQPLARtPQPssP
O14545	S327	Sugiyama	TRAFD1 FLN29	DHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQNFLQQAAS
O14545	S480	Sugiyama	TRAFD1 FLN29	ATYNQLSRstsGPRPGCQPssPCVPKLsNsDsQDIQGRNRD
O14715	T1474	Sugiyama	RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3	DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
O14745	S280	Sugiyama	NHERF1 NHERF SLC9A3R1	tNGEIQKENsREALAEAALEsPRPALVRsAssDtsEELNsQ
O14994	S470	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	SYN3	PQRSGsPsQQRLsPQGQQPLsPQsGsPQQQRSPGsPQLSRA
O15027	T593	PSP	SEC16A KIAA0310 SEC16 SEC16L	GETDETTVSQNYRGSVSQPStPSPPKPTGIFQTSANSsFEP
O15047	S468	Sugiyama	SETD1A KIAA0339 KMT2F SET1 SET1A	GPsPEREEVRtsPRPAsPARsGsPAPEttNESVPFAQHSSL
O15061	S1181	Sugiyama	SYNM DMN KIAA0353 SYN	AAsPtGASRSVRHVTLGPGQsPLsREVIFLGPAPACPEAWG
O15067	S1062	Sugiyama	PFAS KIAA0361	SYCLPPTFPKAsVPREPGGPsPRVAILREEGSNGDREMADA
O15143	S336	Sugiyama	ARPC1B ARC41	AAGAGLDsLHKNsVsQIsVLsGGKAKCSQFCTTGMDGGMSI
O15160	S258	Sugiyama	POLR1C POLR1E	DITLLEPVEGEAAEELSRCFsPGVIEVQEVQGKKVARVANP
O15230	S422	Sugiyama	LAMA5 KIAA0533 KIAA1907	GVNCERCLPGFYRSPNHPLDsPHVCRRCNCESDFTDGtCED
O15446	S285	Sugiyama	POLR1G ASE1 CAST CD3EAP PAF49	EDKTVKQEQINTEPLEDtVLsPtKKRKRQKGTEGMEPEEGV
O15523	S70	Sugiyama	DDX3Y DBY	KGFHDKDSSGWSCSKDKDAyssFGsRDSRGKPGYFSERGSG
O15525	S124	PSP	MAFG	LDALRSKYEALQTFARtVARsPVAPARGPLAAGLGPLVPGK
O43175	S251	Sugiyama	PHGDH PGDH3	VVNCARGGIVDEGALLRALQsGQCAGAALDVFTEEPPRDRA
O43521	S69	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	BCL2L11 BIM	GGEGDSCPHGsPQGPLAPPAsPGPFATRsPLFIFMRRSsLL
O43524	S12	EPSD\|PSP	FOXO3 FKHRL1 FOXO3A	_________MAEAPAsPAPLsPLEVELDPEFEPQSRPRsCt
O43524	S294	SIGNOR\|EPSD\|PSP	FOXO3 FKHRL1 FOXO3A	LQTAPEsADDsPsQLsKWPGsPtSRssDELDAWTDFRsRTN
O43524	S344	SIGNOR\|EPSD\|PSP	FOXO3 FKHRL1 FOXO3A	LSPIMAsTELDEVQDDDAPLsPMLYSSSASLSPSVSKPCTV
O43524	S425	SIGNOR\|EPSD\|PSP	FOXO3 FKHRL1 FOXO3A	GGLMQRSSsFPYTTKGsGLGsPtssFNstVFGPssLNsLRQ
O43561	T184	SIGNOR	LAT	VLPDSTPATSTAAPSAPALStPGIRDSAFSMESIDDyVNVP
O43707	T615	Sugiyama	ACTN4	QRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPKRDH
O43707	Y611	Sugiyama	ACTN4	HKEAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVP
O43852	T65	Sugiyama	CALU	FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD
O60244	S986	EPSD\|PSP	MED14 ARC150 CRSP2 CXorf4 DRIP150 EXLM1 RGR1 TRAP170	FVDSNQDARRRsVNEDDNPPsPIGGDMMDsLIsQLQPPPQQ
O60245	T325	Sugiyama	PCDH7 BHPCDH	SPRFEKSVYEADLAENSAPGtPILQLRAADLDVGVNGQIEY
O60331	S650	EPSD\|PSP	PIP5K1C KIAA0589	EEDAPATDIyFPTDERSWVysPLHYSAQAPPAsDGEsDT__
O60610	T768	SIGNOR	DIAPH1 DIAP1	PPPPPFGFGVPAAPVLPFGLtPKKLYKPEVQLRRPNWSKLV
O60664	S91	Sugiyama	PLIN3 M6PRBP1 TIP47	TAAAVsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQ
O60674	S523	SIGNOR	JAK2	PKDKSNLLVFRTNGVsDVPtsPTLQRPTHMNQMVFHKIRNE
O60716	T308	PSP	CTNND1 KIAA0384	sMGyDDLDyGMMsDyGtARRtGtPsDPRRRLRsyEDMIGEE
O60716	T310	PSP	CTNND1 KIAA0384	GyDDLDyGMMsDyGtARRtGtPsDPRRRLRsyEDMIGEEVP
O60716	T906	SIGNOR\|PSP	CTNND1 KIAA0384	EEIQMSNMGsNtKsLDNNystPNERGDHNRtLDRsGDLGDM
O75030	S180	SIGNOR	MITF BHLHE32	CPNQPGDHVMPPVPGSSAPNsPMAMLTLNSNCEKEGFYKFE
O75179	S2041	Sugiyama	ANKRD17 GTAR KIAA0697	NTAPTNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPL
O75179	S2045	Sugiyama	ANKRD17 GTAR KIAA0697	TNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPLDCGs
O75369	S1505	Sugiyama	FLNB FLN1L FLN3 TABP TAP	PSQEGPYMVSVKYADEEIPRsPFKVKVLPTYDASKVtAsGP
O75369	T994	Sugiyama	FLNB FLN1L FLN3 TABP TAP	QGKLDVtILsPsRKVVPCLVtPVtGRENsTAKFIPREEGLY
O75369	T997	Sugiyama	FLNB FLN1L FLN3 TABP TAP	LDVtILsPsRKVVPCLVtPVtGRENsTAKFIPREEGLYAVD
O75369	Y1604	Sugiyama	FLNB FLN1L FLN3 TABP TAP	KtGRYMIGVTYGGDDIPLsPyRIRAtQTGDASKCLAtGPGI
O75410	S276	Sugiyama	TACC1 KIAA1103	GtPLPKAsYHFsPEELDENtsPLLGDARFQKsPPDLKETPG
O75533	T207	Sugiyama	SF3B1 SAP155	AAAsQPPsKRKRRWDQtADQtPGAtPKKLssWDQAEtPGHt
O75533	T211	Sugiyama	SF3B1 SAP155	QPPsKRKRRWDQtADQtPGAtPKKLssWDQAEtPGHtPsLR
O75533	T223	Sugiyama	SF3B1 SAP155	tADQtPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsE
O75533	T227	Sugiyama	SF3B1 SAP155	tPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsEtPGA
O75534	S598	Sugiyama	CSDE1 D1S155E KIAA0885 NRU UNR	KVNKtHsVNGItEEADPTIysGKVIRPLRSVDPTQTEYQGM
O75581	S1490	EPSD\|PSP	LRP6	SSSSssTKGtYFPAILNPPPsPAtERsHYTMEFGYSsNsPs
O75581	T1572	EPSD\|PSP	LRP6	TAKGYTSDLNyDSEPVPPPPtPRSQYLSAEENyESCPPsPY
O75582	S360	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	RPS6KA5 MSK1	RDELDVsNFAEEFtEMDPtYsPAALPQssEKLFQGYsFVAP
O75582	S376	SIGNOR\|iPTMNet	RPS6KA5 MSK1	DPtYsPAALPQssEKLFQGYsFVAPsILFKRNAAVIDPLQF
O75582	T581	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	RPS6KA5 MSK1	IKIIDFGFARLKPPDNQPLKtPCFTLHYAAPELLNQNGYDE
O75582	T700	GPS6	RPS6KA5 MSK1	GLRYNEWLQDGSQLSSNPLMtPDILGSSGAAVHTCVKAtFH
O75676	S343	GPS6	RPS6KA4 MSK2	RsELDVGNFAEEFTRLEPVysPPGsPPPGDPRIFQGYsFVA
O75676	T568	GPS6	RPS6KA4 MSK2	KIIDFGFARLRPQSPGVPMQtPCFTLQYAAPELLAQQGYDE
O75828	S56	Sugiyama	CBR3 SDR21C2	TARDVARGQAAVQQLQAEGLsPRFHQLDIDDLQsIRALRDF
O75909	S36	Sugiyama	CCNK CPR4	NLDHTKPCWYWDKKDLAHTPsQLEGLDPATEARYRREGARF
O94855	S266	Sugiyama	SEC24D KIAA0755	PAQMAGPPQPQKKLDPDSIPsPIQVIENDRASRGGQVYATN
O94868	S688	Sugiyama	FCHSD2 KIAA0769 SH3MD3	PsPDKRssLYFPRsPsANEKsLHAEsPGFsQAsRHtPETSY
O94868	S693	Sugiyama	FCHSD2 KIAA0769 SH3MD3	RssLYFPRsPsANEKsLHAEsPGFsQAsRHtPETSYGKLRP
O94979	S188	Sugiyama	SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334	PEDISCIAWNRQVQHILAsAsPsGRATVWDLRKNEPIIKVS
O94979	S799	Sugiyama	SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334	IMQLRDRLCRAQGEPVAGHEsPKIPyEKQQLPKGRPGPVAG
O95067	S392	Sugiyama	CCNB2	KLLKISMIPQLNSKAVKDLAsPLIGRs______________
O95359	S2321	Sugiyama	TACC2	RPKMKKtPEKLDNtPAsPPRsPAEPNDIPIAKGTYTFDIDK
O95359	T2514	Sugiyama	TACC2	DYPQPSDLSTFVNETKFssPtEELDyRNsYEIEyMEKIGss
O95365	S525	Sugiyama	ZBTB7A FBI1 LRF ZBTB7 ZNF857A	GGAPDPsPGAtAtPGAPAQPssPDARRNGQEKHFKDEDEDE
O95456	S183	Sugiyama	PSMG1 C21LRP DSCR2 PAC1	QITILTCRHVTDYKTSEsTGsLPsPFLRALKTQNFKDSACC
O95456	S186	Sugiyama	PSMG1 C21LRP DSCR2 PAC1	ILTCRHVTDYKTSEsTGsLPsPFLRALKTQNFKDSACCPLL
O95644	S172	SIGNOR\|EPSD\|PSP	NFATC1 NFAT2 NFATC	PstATLSLPsLEAYRDPsCLsPAssLSSRSCNSEAsSYESN
O95817	S289	SIGNOR\|EPSD\|PSP\|Sugiyama	BAG3 BIS	sVQGAssREGsPARsstPLHsPsPIRVHtVVDRPQQPMTHR
O95817	S377	SIGNOR\|PSP	BAG3 BIS	PPSEKVEVKVPPAPVPCPPPsPGPsAVPssPKsVAtEERAA
O95817	T285	SIGNOR\|EPSD\|PSP	BAG3 BIS	PFRssVQGAssREGsPARsstPLHsPsPIRVHtVVDRPQQP
O95997	S165	SIGNOR	PTTG1 EAP1 PTTG TUTR1	PLMILDEERELEKLFQLGPPsPVKMPsPPWESNLLQsPssI
P00338	S161	Sugiyama	LDHA PIG19	DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338	S167	Sugiyama	LDHA PIG19	AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00367	T409	Sugiyama	GLUD1 GLUD	TKSNAPRVKAKIIAEGANGPttPEADKIFLERNIMVIPDLY
P00533	T693	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	EGFR ERBB ERBB1 HER1	IVRKRtLRRLLQERELVEPLtPsGEAPNQALLRILKETEFK
P00966	T219	Sugiyama	ASS1 ASS	KNQAPPGLytKtQDPAKAPNtPDILEIEFKKGVPVKVTNVK
P01100	S362	GPS6\|SIGNOR	FOS G0S7	VFTYPEADSFPSCAAAHRKGsSsNEPSSDSLSsPTLLAL__
P01100	S374	GPS6\|SIGNOR\|ELM\|PSP	FOS G0S7	CAAAHRKGsSsNEPSSDSLSsPTLLAL______________
P01100	T232	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	FOS G0S7	FPEEMSVASLDLTGGLPEVAtPESEEAFTLPLLNDPEPKPS
P01100	T325	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	FOS G0S7	PLHsGSLGMGPMATELEPLCtPVVTCtPSCTAYTSSFVFTY
P01100	T331	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	FOS G0S7	LGMGPMATELEPLCtPVVTCtPSCTAYTSSFVFTYPEADSF
P01106	S77	PSP	MYC BHLHE39	PPAPSEDIWKKFELLPtPPLsPsRRsGLCsPSyVAVTPFsL
P02686	T232	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MBP	GRTQDENPVVHFFKNIVtPRtPPPSQGKGRGLSLSRFsWGA
P03372	S104	SIGNOR\|EPSD\|PSP	ESR1 ESR NR3A1	SEAAAFGSNGLGGFPPLNsVsPsPLMLLHPPPQLsPFLQPH
P03372	S106	SIGNOR\|EPSD\|PSP	ESR1 ESR NR3A1	AAAFGSNGLGGFPPLNsVsPsPLMLLHPPPQLsPFLQPHGQ
P03372	S118	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	ESR1 ESR NR3A1	PPLNsVsPsPLMLLHPPPQLsPFLQPHGQQVPYYLENEPSG
P03372	T311	ELM	ESR1 ESR NR3A1	LWPsPLMIKRSKKNsLALSLtADQMVSALLDAEPPILYSEY
P03973	T78	Sugiyama	SLPI WAP4 WFDC4	PGKKRCCPDTCGIKCLDPVDtPNPTRRKPGKCPVTYGQCLM
P04040	S515	Sugiyama	CAT	ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________
P04040	T511	Sugiyama	CAT	SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____
P04049	S289	SIGNOR\|EPSD\|PSP	RAF1 RAF	tLPVDSRMIEDAIRsHsEsAsPsALsssPNNLsPtGWsQPK
P04049	S296	SIGNOR\|EPSD\|PSP	RAF1 RAF	MIEDAIRsHsEsAsPsALsssPNNLsPtGWsQPKtPVPAQR
P04049	S301	SIGNOR\|EPSD\|PSP	RAF1 RAF	IRsHsEsAsPsALsssPNNLsPtGWsQPKtPVPAQRERAPV
P04075	S36	Sugiyama	ALDOA ALDA	LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075	T37	Sugiyama	ALDOA ALDA	sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04083	S34	Sugiyama	ANXA1 ANX1 LPC1	IENEEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKA
P04083	T265	Sugiyama	ANXA1 ANX1 LPC1	KHDMNKVLDLELKGDIEKCLtAIVKCATSKPAFFAEKLHQA
P04083	T41	Sugiyama	ANXA1 ANX1 LPC1	yVQtVKssKGGPGsAVsPyPtFNPssDVAALHKAIMVKGVD
P04083	Y39	Sugiyama	ANXA1 ANX1 LPC1	QEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKAIMVKG
P04150	S226	SIGNOR\|ELM\|EPSD\|PSP	NR3C1 GRL	KETNEsPWRSDLLIDENCLLsPLAGEDDSFLLEGNSNEDCK
P04181	T39	Sugiyama	OAT	HSSVASATSVATKKtVQGPPtSDDIFEREyKyGAHNyHPLP
P04198	S62	PSP	MYCN BHLHE37 NMYC	STPPGEDIWKKFELLPtPPLsPsRGFAEHSSEPPSWVTEML
P04406	S210	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG
P04406	T211	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04424	S417	PSP	ASL	MAETKGVALNQLSLQELQTIsPLFSGDVICVWDYGHSVEQY
P04626	T701	EPSD\|PSP	ERBB2 HER2 MLN19 NEU NGL	KIRKYtMRRLLQETELVEPLtPsGAMPNQAQMRILKETELR
P04637	S15	SIGNOR\|EPSD\|PSP	TP53 P53	______MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPL
P04637	S392	EPSD\|PSP	TP53 P53	KKGQstsRHKKLMFKtEGPDsD___________________
P04637	T55	ELM	TP53 P53	LPsQAMDDLMLsPDDIEQWFtEDPGPDEAPRMPEAAPPVAP
P04792	S176	Sugiyama	HSPB1 HSP27 HSP28	sLsPEGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEA
P04792	S82	Sugiyama	HSPB1 HSP27 HSP28	AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04792	T184	Sugiyama	HSPB1 HSP27 HSP28	TVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAA
P05187	S177	Sugiyama	ALPP PLAP	RAKKAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADVP
P05387	S74	Sugiyama	RPLP2 D11S2243E RPP2	VIAQGIGKLAsVPAGGAVAVsAAPGsAAPAAGsAPAAAEEK
P05387	S79	Sugiyama	RPLP2 D11S2243E RPP2	IGKLAsVPAGGAVAVsAAPGsAAPAAGsAPAAAEEKKDEKK
P05387	S86	Sugiyama	RPLP2 D11S2243E RPP2	PAGGAVAVsAAPGsAAPAAGsAPAAAEEKKDEKKEEsEEsD
P05412	S63	SIGNOR\|PSP	JUN	ADPVGSLKPHLRAKNsDLLtsPDVGLLKLAsPELERLIIQS
P05412	S73	SIGNOR\|PSP	JUN	LRAKNsDLLtsPDVGLLKLAsPELERLIIQSSNGHItttPt
P05787	S291	Sugiyama	KRT8 CYK8	ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P05787	S432	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	KRT8 CYK8	HtKTTSGYAGGLSSAYGGLtsPGLSYSLGSSFGSGAGSSSF
P05787	S74	iPTMNet	KRT8 CYK8	YGGASGMGGITAVtVNQSLLsPLVLEVDPNIQAVRTQEKEQ
P06239	S42	GPS6\|ELM\|iPTMNet\|EPSD	LCK	NCHYPIVPLDGKGTLLIRNGsEVRDPLVTYEGsNPPAsPLQ
P06239	S59	SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	LCK	RNGsEVRDPLVTYEGsNPPAsPLQDNLVIALHsYEPSHDGD
P06401	S294	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	PGR NR3C3	RFSAPRVALVEQDAPMAPGRsPLATTVMDFIHVPILPLNHA
P06733	S272	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI
P06733	T19	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	__MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733	T205	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733	T26	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733	Y44	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P07101	S62	SIGNOR\|EPSD\|PSP	TH TYH	TGsPWPGTAAPAASYTPTPRsPRFIGRRQsLIEDARKEREA
P07195	S162	Sugiyama	LDHB	DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195	S168	Sugiyama	LDHB	TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195	S320	Sugiyama	LDHB	GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______
P07195	T302	Sugiyama	LDHB	YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD
P07237	T428	Sugiyama	P4HB ERBA2L PDI PDIA1 PO4DB	DKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFPA
P07355	S22	Sugiyama	ANXA2 ANX2 ANX2L4 CAL1H LPC2D	stVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNI
P07437	S168	Sugiyama	TUBB TUBB5 OK/SW-cl.56	GTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
P07437	S172	Sugiyama	TUBB TUBB5 OK/SW-cl.56	ISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSVHQL
P07437	T166	Sugiyama	TUBB TUBB5 OK/SW-cl.56	GMGTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT
P07437	T55	Sugiyama	TUBB TUBB5 OK/SW-cl.56	tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs
P07686	T307	Sugiyama	HEXB HCC7	PEFDTPGHTLSWGKGQKDLLtPCySRQNKLDSFGPINPTLN
P07737	S57	Sugiyama	PFN1	GKtFVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDs
P07737	T65	Sugiyama	PFN1	PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs
P07741	S30	Sugiyama	APRT	EQRIRsFPDFPTPGVVFRDIsPVLKDPASFRAAIGLLARHL
P07814	S1350	Sugiyama	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	YRRRLLsVNIRVRADLRDNysPGWKFNHWELKGVPIRLEVG
P07814	S688	Sugiyama	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	DIIQLQRRGFFICDQPyEPVsPysCKEAPCVLIyIPDGHtK
P07814	S886	Sugiyama	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	EKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPEAKVLFD
P07814	T737	Sugiyama	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	EKTKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRV
P07858	S216	Sugiyama	CTSB CPSB	PPCTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSE
P07864	S161	Sugiyama	LDHC LDH3 LDHX	DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864	S167	Sugiyama	LDHC LDH3 LDHX	VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900	S505	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900	S52	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs
P07900	T317	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08047	S59	SIGNOR\|EPSD\|PSP	SP1 TSFP1	RssstGsssstGGGGQEsQPsPLALLAATCSRIESPNENSN
P08047	T453	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SP1 TSFP1	ETLQNLQLQAVPNSGPIIIRtPTVGPNGQVSWQTLQLQNLQ
P08047	T739	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SP1 TSFP1	LsVGtLPLDsGAGsEGSGtAtPSALITTNMVAMEAICPEGI
P08195	S296	Sugiyama	SLC3A2 MDU1	DLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNYRGEN
P08195	S598	Sugiyama	SLC3A2 MDU1	LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08195	S607	Sugiyama	SLC3A2 MDU1	ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP
P08195	T401	Sugiyama	SLC3A2 MDU1	NSSDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQ
P08235	S196	SIGNOR\|PSP	NR3C2 MCR MLR	VMRAVVKSPIMCHEKSPSVCsPLNMTSSVCSPAGINSVSST
P08235	S227	SIGNOR\|PSP	NR3C2 MCR MLR	PAGINSVSSTTASFGSFPVHsPITQGTPLTCsPNVENRGSR
P08235	S238	SIGNOR\|PSP	NR3C2 MCR MLR	ASFGSFPVHsPITQGTPLTCsPNVENRGSRSHSPAHASNVG
P08235	S263	SIGNOR\|PSP	NR3C2 MCR MLR	NRGSRSHSPAHASNVGsPLssPLSSMKSSISSPPSHCSVKs
P08235	S287	SIGNOR\|PSP	NR3C2 MCR MLR	SMKSSISSPPSHCSVKsPVSsPNNVTLRSSVssPANINNSR
P08235	S361	SIGNOR\|PSP	NR3C2 MCR MLR	FSYTASGTSAGSSTLRDVVPsPDTQEKGAQEVPFPKTEEVE
P08238	S460	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ
P08238	S462	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238	S497	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238	T309	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238	T83	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	sKLDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLG
P08238	T85	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238	T89	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08651	S323	Sugiyama	NFIC NFI	PssPtsSSRNWTEDMEGGIssPVKKtEMDKsPFNsPsPQDs
P08708	S89	Sugiyama	RPS17 RPS17L	ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL
P08865	S75	Sugiyama	RPSA LAMBR LAMR1	WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG
P08865	S78	Sugiyama	RPSA LAMBR LAMR1	LLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtP
P08865	T82	Sugiyama	RPSA LAMBR LAMR1	ARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtPIAGR
P09104	Y44	Sugiyama	ENO2	LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09382	S63	Sugiyama	LGALS1	CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P09651	S368	Sugiyama	HNRNPA1 HNRPA1	FAKPRNQGGyGGssssssyGsGRRF________________
P09874	S372	SIGNOR	PARP1 ADPRT PPOL	KQDRIFPPEtsAsVAAtPPPstAsAPAAVNSsAsADKPLSN
P09874	T373	SIGNOR	PARP1 ADPRT PPOL	QDRIFPPEtsAsVAAtPPPstAsAPAAVNSsAsADKPLSNM
P09917	S272	SIGNOR	ALOX5 LOG5	LPEKLPVtTEMVECSLERQLsLEQEVQQGNIFIVDFELLDG
P09917	S664	SIGNOR	ALOX5 LOG5	AIVSVIAERNKKKQLPYYYLsPDRIPNsVAI__________
P09923	S174	Sugiyama	ALPI	RAKQAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMP
P0DJD0	T1459	Sugiyama	RGPD1 RANBP2L6 RGP1	DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
P10242	S532	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MYB	VAEFQENGPPLLKKIKQEVEsPtDKSGNFFCSHHWEGDSLN
P10253	T197	Sugiyama	GAA	NRLHFTIKDPANRRyEVPLEtPHVHSRAPSPLYSVEFSEEP
P10275	S516	SIGNOR\|EPSD\|PSP	AR DHTR NR3C4	DFTAPDVWYPGGMVSRVPYPsPTCVKSEMGPWMDSYSGPyG
P10275	S651	EPSD\|PSP	AR DHTR NR3C4	KLKKLGNLKLQEEGEAsSttsPTEETTQKLTVSHIEGYECQ
P10301	S201	SIGNOR\|EPSD\|PSP	RRAS	EAFEQLVRAVRKYQEQELPPsPPSAPRKKGGGCPCVLL___
P10398	S186	Sugiyama	ARAF ARAF1 PKS PKS2	RQHEAPsNRPLNELLtPQGPsPRTQHCDPEHFPFPAPANAP
P10398	T181	Sugiyama	ARAF ARAF1 PKS PKS2	LsGGsRQHEAPsNRPLNELLtPQGPsPRTQHCDPEHFPFPA
P10415	S70	SIGNOR\|ELM	BCL2	SSQPGHtPHPAASRDPVARtsPLQtPAAPGAAAGPALsPVP
P10415	S87	SIGNOR\|ELM\|EPSD\|PSP	BCL2	ARtsPLQtPAAPGAAAGPALsPVPPVVHLTLRQAGDDFSRR
P10415	T56	SIGNOR\|EPSD\|PSP	BCL2	GAAPPGAAPAPGIFSSQPGHtPHPAASRDPVARtsPLQtPA
P10415	T69	ELM	BCL2	FSSQPGHtPHPAASRDPVARtsPLQtPAAPGAAAGPALsPV
P10415	T74	SIGNOR\|EPSD\|PSP	BCL2	GHtPHPAASRDPVARtsPLQtPAAPGAAAGPALsPVPPVVH
P10636	S46	PSP	MAPT MAPTL MTBT1 TAU	QGGytMHQDQEGDtDAGLKEsPLQtPTEDGsEEPGsETSDA
P10636	T50	PSP	MAPT MAPTL MTBT1 TAU	tMHQDQEGDtDAGLKEsPLQtPTEDGsEEPGsETSDAKstP
P10809	S225	Sugiyama	HSPD1 HSP60	KtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVL
P10809	S70	Sugiyama	HSPD1 HSP60	AVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLKDKY
P10809	T115	Sugiyama	HSPD1 HSP60	AKLVQDVANNtNEEAGDGtttAtVLARSIAKEGFEKISKGA
P10809	T231	Sugiyama	HSPD1 HSP60	LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI
P10809	T455	Sugiyama	HSPD1 HSP60	GIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLKIP
P10828	S142	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	THRB ERBA2 NR1A2 THR1	ITCEGCKGFFRRTIQKNLHPsYSCKYEGKCVIDKVTRNQCQ
P11142	T38	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P11142	T66	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11274	S382	Sugiyama	BCR BCR1 D22S11	MFRDKsRsPsQNsQQsFDSssPPtPQCHKRHRHCPVVVSEA
P11274	T385	Sugiyama	BCR BCR1 D22S11	DKsRsPsQNsQQsFDSssPPtPQCHKRHRHCPVVVSEATIV
P11362	S777	SIGNOR\|EPSD\|PSP	FGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFR	IVALTSNQEyLDLSMPLDQysPsFPDTRsstCsSGEDsVFS
P11388	S1213	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	TOP2A TOP2	LPGKGGKAKGKKTQMAEVLPsPRGQRVIPRITIEMKAEAEK
P11388	S1247	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	TOP2A TOP2	MKAEAEKKNKKKIKNENtEGsPQEDGVELEGLKQRLEKKQK
P11388	S1354	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	TOP2A TOP2	EDFsDFDEKtDDEDFVPsDAsPPKtKTsPKLsNKELKPQKs
P11388	S1361	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	TOP2A TOP2	EKtDDEDFVPsDAsPPKtKTsPKLsNKELKPQKsVVsDLEA
P11388	S1393	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	TOP2A TOP2	KsVVsDLEADDVKGsVPLsssPPAtHFPDEtEItNPVPKKN
P11940	S315	Sugiyama	PABPC1 PAB1 PABP PABP1 PABPC2	NLyVKNLDDGIDDERLRKEFsPFGtItsAKVMMEGGRSKGF
P11940	S322	Sugiyama	PABPC1 PAB1 PABP PABP1 PABPC2	DDGIDDERLRKEFsPFGtItsAKVMMEGGRSKGFGFVCFss
P12268	S122	Sugiyama	IMPDH2 IMPD2	NEVRKVKKyEQGFITDPVVLsPKDRVRDVFEAKARHGFCGI
P12270	S2155	Sugiyama	TPR	PstPtLVVPHRtDGFAEAIHsPQVAGVPRFRFGPPEDMPQT
P12277	S128	Sugiyama	CKB CKBB	TDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsR
P12277	S129	Sugiyama	CKB CKBB	DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG
P12277	T35	Sugiyama	CKB CKBB	PAEDEFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDD
P12980	S36	EPSD\|PSP	LYL1 BHLHA18	EKAEMVCAPsPAPAPPPKPAsPGPPQVEEVGHRGGssPPRL
P13489	S84	Sugiyama	RNH1 PRI RNH	RSNELGDVGVHCVLQGLQtPsCKIQKLSLQNCCLTGAGCGV
P13489	T82	Sugiyama	RNH1 PRI RNH	NLRSNELGDVGVHCVLQGLQtPsCKIQKLSLQNCCLTGAGC
P13631	S79	EPSD\|PSP	RARG NR1B3	ASLSVETQSTSSEEMVPSsPsPPPPPRVYKPCFVCNDKSSG
P13639	S387	Sugiyama	EEF2 EF2	yRCELLyEGPPDDEAAMGIKsCDPKGPLMMYISKMVPTSDK
P13639	S595	Sugiyama	EEF2 EF2	PVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGLAE
P13667	S124	Sugiyama	PDIA4 ERP70 ERP72	IANILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKILK
P13667	S482	Sugiyama	PDIA4 ERP70 ERP72	VKDLGLsEsGEDVNAAILDEsGKKFAMEPEEFDsDtLREFV
P13798	S304	Sugiyama	APEH D3F15S2 D3S48E DNF15S2	YVDLIGGKCELLSDDsLAVssPRLSPDQCRIVYLQYPSLIP
P13807	S723	Sugiyama	GYS1 GYS	TSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN______
P13807	S727	Sugiyama	GYS1 GYS	KRNsVDtAtsssLstPsEPLsPtssLGEERN__________
P13807	T721	Sugiyama	GYS1 GYS	sSTSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN____
P13929	Y44	Sugiyama	ENO3	LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P14314	S442	Sugiyama	PRKCSH G19P1	EYVYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSA
P14314	T469	Sugiyama	PRKCSH G19P1	WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14598	S345	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NCF1 NOXO2 SH3PXD1A	RRNsVRFLQQRRRQARPGPQsPGsPLEEERQtQRsKPQPAV
P14598	S348	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	NCF1 NOXO2 SH3PXD1A	sVRFLQQRRRQARPGPQsPGsPLEEERQtQRsKPQPAVPPR
P14618	S37	PSP\|Sugiyama	PKM OIP3 PK2 PK3 PKM2	QLHAAMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRs
P14618	T41	Sugiyama	PKM OIP3 PK2 PK3 PKM2	AMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtL
P14625	S552	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	KEKQDKIyFMAGsSRKEAEssPFVERLLKKGyEVIyLTEPV
P14635	S126	ELM	CCNB1 CCNB	EPEPVKEEKLsPEPILVDTAsPsPMETsGCAPAEEDLCQAF
P14635	S128	ELM	CCNB1 CCNB	EPVKEEKLsPEPILVDTAsPsPMETsGCAPAEEDLCQAFsD
P14784	T476	EPSD\|PSP	IL2RB IL15RB	PPSLQERVPRDWDPQPLGPPtPGVPDLVDFQPPPELVLREA
P14866	S101	Sugiyama	HNRNPL HNRPL P/OKcl.14	GAAGGGGGGENyDDPHKtPAsPVVHIRGLIDGVVEADLVEA
P14868	S369	Sugiyama	DARS1 DARS PIG40	CEALAMLREAGVEMGDEDDLstPNEKLLGHLVKEKyDTDFy
P14921	T38	SIGNOR\|ELM\|iPTMNet\|EPSD	ETS1 EWSR2	KVDLELFPsPDMECADVPLLtPSsKEMMSQALKATFSGFTK
P15056	S151	SIGNOR\|PSP	BRAF BRAF1 RAFB1	LPSSLSVFQNPTDVARsNPKsPQKPIVRVFLPNKQRTVVPA
P15056	T401	SIGNOR\|EPSD\|PSP	BRAF BRAF1 RAFB1	DLIRDQGFRGDGGsttGLsAtPPAsLPGSLTNVKALQKsPG
P15056	T753	SIGNOR\|EPSD\|PSP	BRAF BRAF1 RAFB1	LNRAGFQTEDFSLYACAsPKtPIQAGGYGAFPVH_______
P15336	T69	SIGNOR\|EPSD\|PSP\|Sugiyama	ATF2 CREB2 CREBP1	HEMtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELA
P15336	T71	GPS6\|SIGNOR\|EPSD\|PSP\|Sugiyama	ATF2 CREB2 CREBP1	MtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELAsP
P15408	S320	PSP	FOSL2 FRA2	CSKAHRRssssGDQssDsLNsPtLLAL______________
P15408	T322	PSP	FOSL2 FRA2	KAHRRssssGDQssDsLNsPtLLAL________________
P15531	S125	Sugiyama	NME1 NDPKA NM23	RGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDyTsC
P15559	S82	Sugiyama	NQO1 DIA4 NMOR1	DPANFQYPAESVLAYKEGHLsPDIVAEQKKLEAADLVIFQF
P15923	T355	SIGNOR\|ELM\|EPSD	TCF3 BHLHB21 E2A ITF1	ALAsIysPDHssNNFsssPstPVGsPQGLAGTSQWPRAGAP
P15976	S170	GPS6	GATA1 ERYF1 GF1	PALPSSLPVPNsAYGGPDFSsTFFsPtGsPLNSAAYSsPKL
P15976	S174	GPS6	GATA1 ERYF1 GF1	SSLPVPNsAYGGPDFSsTFFsPtGsPLNSAAYSsPKLRGTL
P15976	S26	GPS6	GATA1 ERYF1 GF1	LGSLGTSEPLPQFVDPALVSsTPESGVFFPSGPEGLDAAAS
P15976	T176	GPS6	GATA1 ERYF1 GF1	LPVPNsAYGGPDFSsTFFsPtGsPLNSAAYSsPKLRGTLPL
P16144	S1356	EPSD\|PSP	ITGB4	DAQSGEDYDSFLMYSDDVLRsPSGsQRPsVSDDTGCGWKFE
P16152	S56	Sugiyama	CBR1 CBR CRN SDR21C1	TARDVTRGQAAVQQLQAEGLsPRFHQLDIDDLQsIRALRDF
P16278	S433	Sugiyama	GLB1 ELNR1	YGFVLYRTTLPQDCSNPAPLssPLNGVHDRAyVAVDGIPQG
P16949	S25	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP\|Sugiyama	STMN1 C1orf215 LAP18 OP18	DIQVKELEKRAsGQAFELILsPRsKEsVPEFPLsPPKKKDL
P16949	S38	GPS6\|SIGNOR\|ELM\|EPSD\|PSP\|Sugiyama	STMN1 C1orf215 LAP18 OP18	QAFELILsPRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAE
P17174	S93	Sugiyama	GOT1	PILGLAEFRsCAsRLALGDDsPALKEKRVGGVQsLGGtGAL
P17302	S255	SIGNOR\|iPTMNet	GJA1 GJAL	GVKDRVKGKSDPyHATsGALsPAKDCGsQKyAyFNGCssPt
P17302	S279	SIGNOR\|iPTMNet	GJA1 GJAL	DCGsQKyAyFNGCssPtAPLsPMsPPGyKLVTGDRNNssCR
P17302	S282	SIGNOR\|iPTMNet	GJA1 GJAL	sQKyAyFNGCssPtAPLsPMsPPGyKLVTGDRNNssCRNYN
P17480	T117	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	UBTF UBF UBF1	KNPYKGKKLKKHPDFPKKPLtPYFRFFMEKRAKYAKLHPEM
P17480	T201	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	UBTF UBF UBF1	EDHPDLIQNAKKSDIPEKPKtPQQLWYtHEKKVYLKVRPDA
P17535	S100	SIGNOR	JUND	SAAPPDGLLAsPDLGLLKLAsPELERLIIQSNGLVtttPTS
P17542	S122	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	TAL1 BHLHA17 SCL TCL5	APAPASVTAELPGDGRMVQLsPPALAAPAAPGRALLYSLSQ
P17544	T51	Sugiyama	ATF7 ATFA	HEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELA
P17544	T53	Sugiyama	ATF7 ATFA	MTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELASS
P17655	S50	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CAPN2 CANPL2	QDYEALRNECLEAGTLFQDPsFPAIPSALGFKELGPYSSKT
P17676	T235	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CEBPB TCF5 PP9092	AVPsGssGsLstsssssPPGtPsPADAKAPPTACyAGAAPA
P17812	S575	Sugiyama	CTPS1 CTPS	LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____
P17813	S521	Sugiyama	ENG END	GGTVELIQGRAAKGNCVSLLsPSPEGDPRFSFLLHFYTVPI
P17861	S181	SIGNOR\|EPSD\|PSP	XBP1 TREB5 XBP2	SAESAALRLRAPLQQVQAQLsPLQNISPWILAVLTLQIQSL
P17861	S68	SIGNOR\|EPSD\|PSP	XBP1 TREB5 XBP2	PEAASGGLPQARKRQRLTHLsPEEKALRRKLKNRVAAQTAR
P17980	S376	Sugiyama	PSMC3 TBP1	MPNEEARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQC
P17987	S551	Sugiyama	TCP1 CCT1 CCTA	IKLHPESKDDKHGsyEDAVHsGALND_______________
P18545	T22	iPTMNet	PDE6G PDEG	NLEPPKAEFRSATRVAGGPVtPRKGPPKFKQRQTRQFKSKP
P18669	S14	Sugiyama	PGAM1 PGAMA CDABP0006	_______MAAYKLVLIRHGEsAWNLENRFsGWyDADLsPAG
P18669	S31	Sugiyama	PGAM1 PGAMA CDABP0006	HGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALRDAGyE
P19404	T51	Sugiyama	NDUFV2	QNGAGGALFVHRDTPENNPDtPFDFTPENyKRIEAIVKNYP
P19419	S324	SIGNOR	ELK1	sPEISQPQKGRKPRDLELPLsPsLLGGPGPERtPGSGSGSG
P19419	S383	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	ELK1	tPVLLtPSSLPPSIHFWSTLsPIAPRsPAKLSFQFPSSGSA
P19419	S389	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	ELK1	PSSLPPSIHFWSTLsPIAPRsPAKLSFQFPSSGSAQVHIPS
P19419	S422	SIGNOR	ELK1	SAQVHIPSISVDGLStPVVLsPGPQKP______________
P19419	T336	SIGNOR	ELK1	PRDLELPLsPsLLGGPGPERtPGSGSGSGLQAPGPALtPSL
P19793	S260	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	RXRA NR2B1	LAVEPKTETyVEANMGLNPssPNDPVtNICQAADKQLFTLV
P19793	T82	SIGNOR\|ELM	RXRA NR2B1	GPPFsVISSPMGPHSMsVPTtPTLGFSTGSPQLSSPMNPVS
P20339	S123	EPSD\|PSP	RAB5A RAB5	TNEESFARAKNWVKELQRQAsPNIVIALSGNKADLANKRAV
P21333	S1084	Sugiyama	FLNA FLN FLN1	PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV
P21333	S1533	Sugiyama	FLNA FLN FLN1	PSREGPysIsVLyGDEEVPRsPFKVKVLPTHDASKVKAsGP
P21333	S1630	Sugiyama	FLNA FLN FLN1	PDVTGRYTILIKYGGDEIPFsPyRVRAVPTGDASKCTVTVS
P21333	S2319	Sugiyama	FLNA FLN FLN1	VQEPGDyEVsVKFNEEHIPDsPFVVPVAsPsGDARRLtVss
P21333	S2327	Sugiyama	FLNA FLN FLN1	VsVKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKV
P21333	S2329	Sugiyama	FLNA FLN FLN1	VKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKVNQ
P21802	S780	PSP	FGFR2 BEK KGFR KSAM	ILTLTTNEEyLDLSQPLEQYsPsYPDTRSSCSSGDDSVFSP
P22102	S88	Sugiyama	GART PGFT PRGS	EFVVVGPEAPLAAGIVGNLRsAGVQCFGPTAEAAQLEssKR
P22234	S27	Sugiyama	PAICS ADE2 AIRC PAIS	LNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAGNAARK
P22314	T233	Sugiyama	UBA1 A1S9T UBE1	GEQPLSAMVSMVTKDNPGVVtCLDEARHGFESGDFVSFSEV
P22626	S225	Sugiyama	HNRNPA2B1 HNRPA2B1	GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P22681	S900	Sugiyama	CBL CBL2 RNF55	IAQNNIEMAKNILREFVSIssPAHVAT______________
P23284	T81	Sugiyama	PPIB CYPB	IFGLFGKTVPKTVDNFVALAtGEKGFGYKNSKFHRVIKDFM
P23396	T221	Sugiyama	RPS3 OK/SW-cl.26	KKPLPDHVsIVEPKDEILPttPIsEQKGGKPEPPAMPQPVP
P23396	T42	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	RPS3 OK/SW-cl.26	NEFLtRELAEDGysGVEVRVtPTRTEIIILATRTQNVLGEK
P23415	S408	PSP	GLRA1	ISVKGANNSNTTNPPPAPSKsPEEMRKLFIQRAKKIDKISR
P23443	S441	SIGNOR	RPS6KB1 STK14A	SVKEKFsFEPKIRsPRRFIGsPRtPVsPVKFsPGDFWGRGA
P23443	T444	SIGNOR	RPS6KB1 STK14A	EKFsFEPKIRsPRRFIGsPRtPVsPVKFsPGDFWGRGASAS
P23588	S122	Sugiyama	EIF4B	NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA
P23921	S559	Sugiyama	RRM1 RR1	ALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTPTDLW
P24534	S8	Sugiyama	EEF1B2 EEF1B EF1B	_____________MGFGDLKsPAGLQVLNDyLADKSYIEGY
P24928	S1619	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	POLR2A POLR2	AYEPRSPGGYTPQSPSysPtsPsYsPTsPSYSPTSPNYSPT
P24928	S1626	SIGNOR	POLR2A POLR2	GGYTPQSPSysPtsPsYsPTsPSYSPTSPNYSPTSPSYsPT
P24928	S1647	SIGNOR	POLR2A POLR2	PSYSPTSPNYSPTSPSYsPTsPSYsPTsPSYSPTSPSYsPT
P24928	S1654	SIGNOR	POLR2A POLR2	PNYSPTSPSYsPTsPSYsPTsPSYSPTSPSYsPTsPSYsPT
P24928	S1668	SIGNOR	POLR2A POLR2	PSYsPTsPSYSPTSPSYsPTsPSYsPTsPSYSPTSPSYSPT
P24928	S1675	SIGNOR	POLR2A POLR2	PSYSPTSPSYsPTsPSYsPTsPSYSPTSPSYSPTSPSYsPT
P24928	S1696	SIGNOR	POLR2A POLR2	PSYSPTSPSYSPTSPSYsPTsPSYSPTSPSYSPTSPSYsPT
P24928	S1717	SIGNOR	POLR2A POLR2	PSYSPTSPSYSPTSPSYsPTsPSYsPTsPSYSPTSPSYsPT
P24928	S1724	SIGNOR	POLR2A POLR2	PSYSPTSPSYsPTsPSYsPTsPSYSPTSPSYsPTsPSYSPT
P24928	S1738	SIGNOR	POLR2A POLR2	PSYsPTsPSYSPTSPSYsPTsPSYSPTSPNYSPTSPNYTPT
P24928	S1766	SIGNOR	POLR2A POLR2	PNYSPTSPNYTPTSPSYsPTsPSYSPTSPNYTPTSPNYsPT
P24928	S1787	SIGNOR	POLR2A POLR2	PSYSPTSPNYTPTSPNYsPTsPSYSPTSPSYSPTSPSYSPS
P24928	S1864	SIGNOR	POLR2A POLR2	PsysPssPEytPtsPKysPtsPKysPtsPKysPtsPtysPt
P24928	S1871	SIGNOR	POLR2A POLR2	PEytPtsPKysPtsPKysPtsPKysPtsPtysPttPKysPt
P24928	S1882	SIGNOR	POLR2A POLR2	PtsPKysPtsPKysPtsPtysPttPKysPtsPtysPtsPVy
P24928	S1892	SIGNOR	POLR2A POLR2	PKysPtsPtysPttPKysPtsPtysPtsPVytPtsPKysPt
P24928	S1899	SIGNOR	POLR2A POLR2	PtysPttPKysPtsPtysPtsPVytPtsPKysPtsPtysPt
P24928	S1913	SIGNOR	POLR2A POLR2	PtysPtsPVytPtsPKysPtsPtysPtsPKysPtsPtysPt
P24928	S1920	SIGNOR	POLR2A POLR2	PVytPtsPKysPtsPtysPtsPKysPtsPtysPtsPKGstY
P24928	S1927	SIGNOR	POLR2A POLR2	PKysPtsPtysPtsPKysPtsPtysPtsPKGstYsPtsPGY
P24928	S1934	SIGNOR	POLR2A POLR2	PtysPtsPKysPtsPtysPtsPKGstYsPtsPGYsPtsPTY
P24928	S1944	SIGNOR	POLR2A POLR2	sPtsPtysPtsPKGstYsPtsPGYsPtsPTYSLTsPAIsPD
P24928	S1951	SIGNOR	POLR2A POLR2	sPtsPKGstYsPtsPGYsPtsPTYSLTsPAIsPDDsDEEN_
P24941	T160	SIGNOR\|EPSD\|PSP	CDK2 CDKN2	AIKLADFGLARAFGVPVRtytHEVVtLWyRAPEILLGCKYY
P25098	S670	SIGNOR\|ELM\|iPTMNet	GRK2 ADRBK1 BARK BARK1	AYREAQQLVQRVPKMKNKPRsPVVELsKVPLVQRGsANGL_
P25205	T722	Sugiyama	MCM3	GDsyDPyDFsDtEEEMPQVHtPKTADsQEtKEsQKVELsES
P25786	S230	Sugiyama	PSMA1 HC2 NU PROS30 PSC2	VsIGIVGKDLEFTIyDDDDVsPFLEGLEERPQRKAQPAQPA
P26640	S301	Sugiyama	VARS1 G7A VARS VARS2	DLPtPPGEKKDVSGPMPDsysPRYVEAAWYPWWEQQGFFKP
P27361	T17	Sugiyama	MAPK3 ERK1 PRKM3	____MAAAAAQGGGGGEPRRtEGVGPGVPGEVEMVKGQPFD
P27361	T198	Sugiyama	MAPK3 ERK1 PRKM3	CDLKICDFGLARIADPEHDHtGFLtEyVAtRWyRAPEIMLN
P27361	T202	SIGNOR\|iPTMNet\|EPSD\|Sugiyama	MAPK3 ERK1 PRKM3	ICDFGLARIADPEHDHtGFLtEyVAtRWyRAPEIMLNSKGY
P27361	T207	GPS6\|SIGNOR\|EPSD\|PSP	MAPK3 ERK1 PRKM3	LARIADPEHDHtGFLtEyVAtRWyRAPEIMLNSKGYTKSID
P27361	T368	Sugiyama	MAPK3 ERK1 PRKM3	FAMELDDLPKERLKELIFQEtARFQPGVLEAP_________
P27361	Y204	SIGNOR\|iPTMNet\|EPSD\|PSP\|Sugiyama	MAPK3 ERK1 PRKM3	DFGLARIADPEHDHtGFLtEyVAtRWyRAPEIMLNSKGYTK
P27708	S1038	Sugiyama	CAD	QLPNNMAMALHRQQCRVLGtsPEAIDSAENRFKFSRLLDTI
P27708	T456	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CAD	NIATVQTSQGLADKVYFLPItPHYVTQVIRNERPDGVLLTF
P27797	S52	Sugiyama	CALR CRTC	GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797	T34	Sugiyama	CALR CRTC	LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P27824	S362	Sugiyama	CANX	WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK
P27824	S564	GPS6	CANX	GEEKLEEKQKsDAEEDGGtVsQEEEDRKPKAEEDEILNRsP
P27824	S583	EPSD\|PSP\|Sugiyama	CANX	VsQEEEDRKPKAEEDEILNRsPRNRKPRRE___________
P28066	S172	Sugiyama	PSMA5	QLFHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLK
P28066	S179	Sugiyama	PSMA5	sGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSL
P28324	S381	PSP	ELK4 SAP1	tPIILtPSPLLSSIHFWSTLsPVAPLsPARLQGANTLFQFP
P28324	S387	PSP	ELK4 SAP1	PSPLLSSIHFWSTLsPVAPLsPARLQGANTLFQFPSVLNSH
P28562	S296	SIGNOR	DUSP1 CL100 MKP1 PTPN10 VH1	TNRVKLDEAFEFVKQRRSIIsPNFSFMGQLLQFESQVLAPH
P28562	S323	SIGNOR	DUSP1 CL100 MKP1 PTPN10 VH1	GQLLQFESQVLAPHCSAEAGsPAMAVLDRGTsTTTVFNFPV
P28562	S359	SIGNOR\|PSP	DUSP1 CL100 MKP1 PTPN10 VH1	FNFPVSIPVHSTNSALSYLQsPITTsPSC____________
P28562	S364	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	DUSP1 CL100 MKP1 PTPN10 VH1	SIPVHSTNSALSYLQsPITTsPSC_________________
P28715	S384	Sugiyama	ERCC5 ERCM2 XPG XPGC	ENRRQARGRNAPAAVDEGsIsPRtLSAIKRALDDDEDVKVC
P29401	S295	Sugiyama	TKT	ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI
P29401	S439	Sugiyama	TKT	VSIGEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVE
P29401	T287	Sugiyama	TKT	AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP
P29590	S36	PSP	PML MYL PP8675 RNF71 TRIM19	ARPQEPtMPPPEtPsEGRQPsPsPsPtERAPAsEEEFQFLR
P29590	S38	PSP	PML MYL PP8675 RNF71 TRIM19	PQEPtMPPPEtPsEGRQPsPsPsPtERAPAsEEEFQFLRCQ
P29590	S40	PSP	PML MYL PP8675 RNF71 TRIM19	EPtMPPPEtPsEGRQPsPsPsPtERAPAsEEEFQFLRCQQC
P29590	S527	EPSD\|PSP	PML MYL PP8675 RNF71 TRIM19	EQPRPstsKAVsPPHLDGPPsPRsPVIGsEVFLPNSNHVAs
P29590	S530	SIGNOR\|EPSD\|PSP	PML MYL PP8675 RNF71 TRIM19	RPstsKAVsPPHLDGPPsPRsPVIGsEVFLPNSNHVAsGAG
P29590	T28	PSP	PML MYL PP8675 RNF71 TRIM19	sPRPQQDPARPQEPtMPPPEtPsEGRQPsPsPsPtERAPAs
P29692	S133	Sugiyama	EEF1D EF1D	NVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPAEDDE
P29692	S70	Sugiyama	EEF1D EF1D	IARARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVE
P29966	S101	Sugiyama	MARCKS MACS PRKCSL	sPsAAEKGEPAAAAAPEAGAsPVEKEAPAEGEAAEPGsPtA
P29966	S27	Sugiyama	MARCKS MACS PRKCSL	KTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAsP
P29966	S46	EPSD\|PSP	MARCKS MACS PRKCSL	ssPsKANGQENGHVKVNGDAsPAAAEsGAKEELQANGsAPA
P30041	T44	Sugiyama	PRDX6 AOP2 KIAA0106	RFHDFLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKR
P30041	T48	Sugiyama	PRDX6 AOP2 KIAA0106	FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL
P30050	S157	Sugiyama	RPL12	QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P30050	S165	Sugiyama	RPL12	GRHPHDIIDDINsGAVECPAs____________________
P30050	S26	Sugiyama	RPL12	DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI
P30050	T135	Sugiyama	RPL12	QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI
P30086	S60	Sugiyama	PEBP1 PBP PEBP	VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK
P30086	T42	Sugiyama	PEBP1 PBP PEBP	QHPLHVTYAGAAVDELGKVLtPtQVKNRPtsIsWDGLDsGK
P30086	T51	Sugiyama	PEBP1 PBP PEBP	GAAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDP
P30101	S443	Sugiyama	PDIA3 ERP57 ERP60 GRP58	LsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLN
P30101	T120	Sugiyama	PDIA3 ERP57 ERP60 GRP58	yPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPASVPLR
P31327	T45	Sugiyama	CPS1	AHQKWKFSRPGIRLLSVKAQtAHIVLEDGtKMKGYSFGHPS
P31645	T616	EPSD\|PSP	SLC6A4 HTT SERT	RLIITPGtFKERIIKsItPEtPTEIPCGDIRLNAV______
P31937	S88	Sugiyama	HIBADH	YDVFPDACKEFQDAGEQVVSsPADVAEKADRIITMLPTSIN
P31939	S300	Sugiyama	ATIC PURH OK/SW-cl.86	sEDEAKVCMVyDLyKTLtPIsAAyARARGADRMssFGDFVA
P31939	T297	Sugiyama	ATIC PURH OK/SW-cl.86	IPLsEDEAKVCMVyDLyKTLtPIsAAyARARGADRMssFGD
P31943	S104	Sugiyama	HNRNPH1 HNRPH HNRPH1	EVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK
P32121	S14	SIGNOR\|EPSD\|PSP	ARRB2 ARB2 ARR2	_______MGEKPGTRVFKKSsPNCKLTVYLGKRDFVDHLDK
P32121	T276	SIGNOR\|EPSD\|PSP	ARRB2 ARB2 ARR2	QLEQDDQVSPSSTFCKVYTItPLLSDNREKRGLALDGKLKH
P33076	S280	SIGNOR\|EPSD\|PSP	CIITA MHC2TA	VPQASQVPPPSGFTVHGLPTsPDRPGsTsPFAPsATDLPSM
P33076	S288	SIGNOR\|EPSD\|PSP	CIITA MHC2TA	PPSGFTVHGLPTsPDRPGsTsPFAPsATDLPSMPEPALTSR
P33981	S821	EPSD\|PSP	TTK MPS1 MPS1L1	MAKGttEEMKyVLGQLVGLNsPNsILKAAKTLyEHYsGGES
P34931	T40	Sugiyama	HSPA1L	VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P35228	S745	SIGNOR\|EPSD\|PSP	NOS2 NOS2A	SSMHAKNVFTMRLKSRQNLQsPTSSRATILVELSCEDGQGL
P35236	S93	SIGNOR	PTPN7	HFLRTAGHPLTRWALQRQPPsPKQLEEEFLKIPsNFVsPED
P35236	T66	SIGNOR	PTPN7	VALMLDVRSLGAVEPICsVNtPREVtLHFLRTAGHPLTRWA
P35250	S30	Sugiyama	RFC2	AGEVEAQDSDPAPAFSKAPGsAGHyELPWVEKYRPVKLNEI
P35269	T389	Sugiyama	GTF2F1 RAP74	PPKRERKPsGGSSRGNsRPGtPsAEGGstsstLRAAASKLE
P35568	S616	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	IRS1	GGHHRPDsstLHtDDGyMPMsPGVAPVPSGRKGsGDyMPMs
P35568	S636	SIGNOR	IRS1	sPGVAPVPSGRKGsGDyMPMsPKsVSAPQQIINPIRRHPQR
P35606	T828	Sugiyama	COPB2	EEWVKETHADLWPAKQyPLVtPNEERNVMEEGKDFQPSRst
P35611	S12	Sugiyama	ADD1 ADDA	_________MNGDsRAAVVtsPPPttAPHKERyFDRVDENN
P35611	S358	Sugiyama	ADD1 ADDA	PDNLVLLNPEKYKAKsRsPGsPVGEGtGsPPKWQIGEQEFE
P35613	S278	Sugiyama	BSG UNQ6505/PRO21383	ITDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQ
P35637	S346	Sugiyama	FUS TLS	TDRETGKLKGEAtVsFDDPPsAKAAIDWFDGKEFsGNPIKV
P35658	S1710	EPSD\|PSP	NUP214 CAIN CAN KIAA0023	TGSTASTAAATPQVSSSGFSsPAFGTTAPGVFGQTTFGQAS
P35658	S1809	EPSD\|PSP	NUP214 CAIN CAN KIAA0023	SSPNTGGGLFGQSNAPAFGQsPGFGQGGSVFGGTSAATTTA
P35998	T193	Sugiyama	PSMC2 MSS1	TYSDVGGCKEQIEKLREVVEtPLLHPERFVNLGIEPPKGVL
P36578	S63	Sugiyama	RPL4 RPL1	NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG
P36578	T69	Sugiyama	RPL4 RPL1	RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P36956	S117	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SREBF1 BHLHD1 SREBP1	LSPPQPAPTPLKMYPSMPAFsPGPGIKEESVPLSILQTPTP
P37231	S112	SIGNOR	PPARG NR1C3	DYKYDLKLQEyQSAIKVEPAsPPYYSEKTQLYNKPHEEPSN
P37802	S145	Sugiyama	TAGLN2 KIAA0120 CDABP0035	VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN
P37802	T180	Sugiyama	TAGLN2 KIAA0120 CDABP0035	RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802	T190	Sugiyama	TAGLN2 KIAA0120 CDABP0035	GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P38646	S212	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P38646	T86	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646	T87	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	VAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKR
P38936	S130	SIGNOR\|ELM\|EPSD\|PSP	CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1	HVDLsLSCTLVPRsGEQAEGsPGGPGDSQGRKRRQtsMTDF
P38936	S98	EPSD\|PSP	CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1	LPtGPRRGRDELGGGRRPGtsPALLQGTAEEDHVDLsLSCT
P38936	T57	SIGNOR\|ELM	CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1	LMAGCIQEARERWNFDFVtEtPLEGDFAWERVRGLGLPKLy
P40763	S701	Sugiyama	STAT3 APRF	EAFGKyCRPEsQEHPEADPGsAAPyLKTKFICVtPttCsNt
P40763	S727	SIGNOR\|PSP	STAT3 APRF	KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS
P40763	Y705	SIGNOR	STAT3 APRF	KyCRPEsQEHPEADPGsAAPyLKTKFICVtPttCsNtIDLP
P41091	T109	Sugiyama	EIF2S3 EIF2G	YKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLVRH
P41182	S333	SIGNOR\|EPSD\|PSP	BCL6 BCL5 LAZ3 ZBTB27 ZNF51	ALHFEPPNAPLNRKGLVsPQsPQKsDCQPNsPtESCSSKNA
P41182	S343	SIGNOR\|EPSD\|PSP	BCL6 BCL5 LAZ3 ZBTB27 ZNF51	LNRKGLVsPQsPQKsDCQPNsPtESCSSKNACILQAsGsPP
P41212	S213	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	ETV6 TEL TEL1	sPDPEQRPLRsPLDNMIRRLsPAERAQGPRPHQENNHQESY
P41212	S257	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	ETV6 TEL TEL1	VSPMENNHCPASSESHPKPSsPRQESTRVIQLMPsPIMHPL
P41235	S138	PSP	HNF4A HNF4 NR2A1 TCF14	KKCFRAGMKKEAVQNERDRIstRRssYEDssLPsINALLQA
P41235	S142	PSP	HNF4A HNF4 NR2A1 TCF14	RAGMKKEAVQNERDRIstRRssYEDssLPsINALLQAEVLS
P41235	S143	PSP	HNF4A HNF4 NR2A1 TCF14	AGMKKEAVQNERDRIstRRssYEDssLPsINALLQAEVLSR
P41235	S147	PSP	HNF4A HNF4 NR2A1 TCF14	KEAVQNERDRIstRRssYEDssLPsINALLQAEVLSRQIts
P41235	S148	PSP	HNF4A HNF4 NR2A1 TCF14	EAVQNERDRIstRRssYEDssLPsINALLQAEVLSRQItsP
P41235	S151	PSP	HNF4A HNF4 NR2A1 TCF14	QNERDRIstRRssYEDssLPsINALLQAEVLSRQItsPVSG
P41235	S167	PSP	HNF4A HNF4 NR2A1 TCF14	ssLPsINALLQAEVLSRQItsPVSGINGDIRAKKIASIADV
P41235	S262	PSP	HNF4A HNF4 NR2A1 TCF14	VLLLGNDYIVPRHCPELAEMsRVsIRILDELVLPFQELQID
P41235	S265	PSP	HNF4A HNF4 NR2A1 TCF14	LGNDYIVPRHCPELAEMsRVsIRILDELVLPFQELQIDDNE
P41235	S313	PSP	HNF4A HNF4 NR2A1 TCF14	IFFDPDAKGLsDPGKIKRLRsQVQVsLEDYINDRQYDSRGR
P41235	S461	PSP	HNF4A HNF4 NR2A1 TCF14	SGsEPYKLLPGAVAtIVKPLsAIPQPtItKQEVI_______
P41235	S95	PSP	HNF4A HNF4 NR2A1 TCF14	SSCDGCKGFFRRSVRKNHMYsCRFSRQCVVDKDKRNQCRYC
P41235	T139	PSP	HNF4A HNF4 NR2A1 TCF14	KCFRAGMKKEAVQNERDRIstRRssYEDssLPsINALLQAE
P41235	T166	PSP	HNF4A HNF4 NR2A1 TCF14	DssLPsINALLQAEVLSRQItsPVSGINGDIRAKKIASIAD
P41235	T467	PSP	HNF4A HNF4 NR2A1 TCF14	KLLPGAVAtIVKPLsAIPQPtItKQEVI_____________
P41235	T469	PSP	HNF4A HNF4 NR2A1 TCF14	LPGAVAtIVKPLsAIPQPtItKQEVI_______________
P41236	T73	GPS6	PPP1R2 IPP2	LAtyHPADKDyGLMKIDEPstPYHsMMGDDEDACsDtEAtE
P41252	S1047	Sugiyama	IARS1 IARS	ESHTEFIFTTIKAPLKPYPVsPsDKVLIQEKTQLKGSELEI
P42166	T160	Sugiyama	TMPO LAP2	KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs
P42167	T160	Sugiyama	TMPO LAP2	KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS
P42224	S727	EPSD\|PSP	STAT1	IsVsEVHPSRLQttDNLLPMsPEEFDEVSRIVGsVEFDSMM
P42229	S780	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	STAT5A STAT5	VARHVEELLRRPMDsLDsRLsPPAGLFTSARGSLS______
P42677	T74	Sugiyama	RPS27 MPS1	VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
P42702	S1044	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	LIFR	KTAGYRPQANVNTWNLVsPDsPRSIDsNSEIVSFGsPCSIN
P42892	S733	Sugiyama	ECE1	VWCSVRTPESSHEGLITDPHsPsRFRVIGSLSNSKEFSEHF
P43364	S174	SIGNOR\|EPSD\|PSP	MAGEA11 MAGE11	TLNVGTLEELPAAEsPsPPQsPQEESFsPTAMDAIFGSLSD
P46527	S10	SIGNOR	CDKN1B KIP1 p27	___________MSNVRVSNGsPsLERMDARQAEHPKPSACR
P46527	S178	SIGNOR	CDKN1B KIP1 p27	DDSSTQNKRANRTEENVsDGsPNAGSVEQtPKKPGLRRRQt
P46527	T187	SIGNOR\|EPSD\|PSP	CDKN1B KIP1 p27	ANRTEENVsDGsPNAGSVEQtPKKPGLRRRQt_________
P46777	S172	Sugiyama	RPL5 MSTP030	RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777	S176	Sugiyama	RPL5 MSTP030	GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46783	S146	Sugiyama	RPS10	TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46937	T119	Sugiyama	YAP1 YAP65	PEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQLGAVsP
P47712	S505	SIGNOR\|ELM	PLA2G4A CPLA2 PLA2G4	RAGKVHNFMLGLNLNTSYPLsPLSDFATQDsFDDDELDAAV
P47756	S207	Sugiyama	CAPZB	MNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKIRst
P47914	S142	Sugiyama	RPL29	KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___
P48637	S415	Sugiyama	GSS	yILMEKIEPEPFENCLLRPGsPARVVQCISELGIFGVYVRQ
P49023	S106	Sugiyama	PXN	PVyGssAKtssVsNPQDsVGsPCsRVGEEEHVysFPNKQKs
P49023	S126	PSP	PXN	sPCsRVGEEEHVysFPNKQKsAEPsPtVMstsLGsNLsELD
P49023	S130	PSP	PXN	RVGEEEHVysFPNKQKsAEPsPtVMstsLGsNLsELDRLLL
P49023	S83	PSP	PXN	LDPLDQWQPSSSRFIHQQPQsssPVyGssAKtssVsNPQDs
P49137	S272	ELM	MAPKAPK2	IMYILLCGYPPFYSNHGLAIsPGMKTRIRMGQYEFPNPEWS
P49137	T222	ELM	MAPKAPK2	ILKLtDFGFAKEttsHNsLttPCytPyyVAPEVLGPEKYDK
P49137	T25	ELM	MAPKAPK2	SQGQsPPVPFPAPAPPPQPPtPALPHPPAQPPPPPPQQFPQ
P49137	T334	ELM	MAPKAPK2	MTItEFMNHPWIMQSTKVPQtPLHtsRVLKEDKERWEDVKE
P49327	S831	Sugiyama	FASN FAS	NPNALFPPVEFPAPRGtPLIsPLIKWDHSLAWDVPAAEDFP
P49327	T2204	Sugiyama	FASN FAS	LRKLQELSSKADEAsELACPtPKEDGLAQQQtQLNLRSLLV
P49327	T827	Sugiyama	FASN FAS	GIDANPNALFPPVEFPAPRGtPLIsPLIKWDHSLAWDVPAA
P49366	S233	GPS6\|SIGNOR\|PSP	DHPS DS	EINNPESVyyWAQKNHIPVFsPALTDGSLGDMIFFHSYKNP
P49407	S412	SIGNOR\|iPTMNet\|EPSD\|PSP	ARRB1 ARR1	ARQRLKGMKDDKEEEEDGtGsPQLNNR______________
P49418	S293	SIGNOR	AMPH AMPH1	PtAsPNHTLAPAsPAPARPRsPsQTRKGPPVPPLPKVtPtK
P49418	S295	SIGNOR	AMPH AMPH1	AsPNHTLAPAsPAPARPRsPsQTRKGPPVPPLPKVtPtKEL
P49448	T409	Sugiyama	GLUD2 GLUDP1	TKSNAPRVKAKIIAEGANGPttPEADKIFLERNILVIPDLY
P49585	S315	SIGNOR	PCYT1A CTPCT PCYT1	PEGALKHMLKEGKGRMLQAIsPKQsPsssPtRERsPsPSFR
P49585	S347	Sugiyama	PCYT1A CTPCT PCYT1	ERsPsPSFRWPFsGKtsPPCsPANLsRHKAAAyDIsEDEED
P49715	S21	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CEBPA CEBP	MESADFYEAEPRPPMssHLQsPPHAPSSAAFGFPRGAGPAQ
P49790	S257	EPSD\|PSP	NUP153	GtLsPsLGNssILKTsQLGDsPFyPGKTTYGGAAAAVRQSK
P49790	S320	EPSD\|PSP	NUP153	SYGVTSstARRILQsLEKMSsPLADAKRIPsIVssPLNsPL
P49790	S334	EPSD\|PSP	NUP153	sLEKMSsPLADAKRIPsIVssPLNsPLDRsGIDItDFQAKR
P49790	S338	EPSD\|PSP	NUP153	MSsPLADAKRIPsIVssPLNsPLDRsGIDItDFQAKREKVD
P49790	S516	EPSD\|PSP	NUP153	TSSPSPINSSQALTNKVQMtsPsstGsPMFKFSsPIVKSTE
P49790	S522	EPSD\|PSP	NUP153	INSSQALTNKVQMtsPsstGsPMFKFSsPIVKSTEANVLPP
P49790	S529	SIGNOR\|EPSD\|PSP	NUP153	TNKVQMtsPsstGsPMFKFSsPIVKSTEANVLPPSSIGFTF
P49790	T369	EPSD\|PSP	NUP153	DFQAKREKVDSQYPPVQRLMtPKPVSIATNRSVYFKPsLtP
P49790	T388	SIGNOR\|EPSD\|PSP	NUP153	MtPKPVSIATNRSVYFKPsLtPsGEFRKTNQRIDNKCSTGY
P49790	T413	EPSD\|PSP	NUP153	FRKTNQRIDNKCSTGYEKNMtPGQNREQRESGFSYPNFSLP
P49792	T1144	Sugiyama	RANBP2 NUP358	GFRRsDDMFTFHGPGKsVFGtPtLETANKNHEtDGGsAHGD
P49792	T2450	Sugiyama	RANBP2 NUP358	DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
P49795	S151	GPS6	RGS19 GAIP GNAI3IP	NQHVVDEKARLIyEDyVSILsPKEVSLDSRVREGINKKMQE
P49815	S540	SIGNOR	TSC2 TSC4	HTHHFNSLLDIIEKVMARSLsPPPELEERDVAAYSASLEDV
P49815	S664	SIGNOR\|EPSD\|PSP	TSC2 TSC4	CVCDYMEPERGSEKKtsGPLsPPtGPPGPAPAGPAVRLGSV
P49841	S9	SIGNOR	GSK3B	____________MSGRPRttsFAEsCKPVQQPsAFGsMKVS
P49841	T43	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	GSK3B	FGsMKVSRDKDGSKVTTVVAtPGQGPDRPQEVSyTDTKVIG
P49903	T387	Sugiyama	SEPHS1 SELD SPS SPS1	IDKPRIIEVAPQVATQNVNPtPGAts_______________
P50502	S181	Sugiyama	ST13 AAG2 FAM10A1 HIP SNC6	LQKPNAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA
P50616	S152	SIGNOR\|EPSD\|PSP	TOB1 TOB TROB1	FNPEAQVFMPISDPASsVsssPsPPFGHsAAVsPTFMPRSt
P50616	S154	SIGNOR\|EPSD\|PSP	TOB1 TOB TROB1	PEAQVFMPISDPASsVsssPsPPFGHsAAVsPTFMPRStQP
P50616	S164	SIGNOR\|EPSD\|PSP	TOB1 TOB TROB1	DPASsVsssPsPPFGHsAAVsPTFMPRStQPLTFTTATFAA
P50991	T50	Sugiyama	CCT4 CCTD SRB	PAQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtI
P51003	S537	SIGNOR	PAPOLA PAP	ALNDSSLDLsMDsDNsMsVPsPtSATKtsPLNSSGsSQGRN
P51003	S545	SIGNOR	PAPOLA PAP	LsMDsDNsMsVPsPtSATKtsPLNSSGsSQGRNsPAPAVTA
P51003	S558	SIGNOR	PAPOLA PAP	PtSATKtsPLNSSGsSQGRNsPAPAVTAASVTNIQATEVSV
P51168	T615	SIGNOR	SCNN1B	APRSPNTGPYPSEQALPIPGtPPPNYDSLRLQPLDVIESDS
P51170	T622	SIGNOR	SCNN1G	LPTFNSALHLPPALGTQVPGtPPPKYNTLRLERAFSNQLTD
P51784	S948	PSP	USP11 UHX1	QRQDVARRLLsPAGssGAPAsPACssPPssEFMDVN_____
P51812	S227	SIGNOR	RPS6KA3 ISPK1 MAPKAPK1B RSK2	IKLTDFGLSKESIDHEKKAysFCGtVEYMAPEVVNRRGHTQ
P51812	T577	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	RPS6KA3 ISPK1 MAPKAPK1B RSK2	IRICDFGFAKQLRAENGLLMtPCytANFVAPEVLKRQGYDA
P51812	Y529	EPSD	RPS6KA3 ISPK1 MAPKAPK1B RSK2	KFFSEREASAVLFTITKTVEyLHAQGVVHRDLKPSNILYVD
P51858	S40	Sugiyama	HDGF HMG1L2	MKGyPHWPARIDEMPEAAVKstANKYQVFFFGTHETAFLGP
P51858	T41	Sugiyama	HDGF HMG1L2	KGyPHWPARIDEMPEAAVKstANKYQVFFFGTHETAFLGPK
P51991	S358	Sugiyama	HNRNPA3 HNRPA3	QQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF
P52565	T160	Sugiyama	ARHGDIA GDIA1	DKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYsIKSR
P52597	S107	Sugiyama	HNRNPF HNRPF	KSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPFGCTKEEI
P52948	S623	Sugiyama	NUP98 ADAR2	KNLNNsNLFsPVNRDsENLAsPsEyPENGERFsFLSKPVDE
P53004	S230	EPSD\|PSP	BLVRA BLVR BVR	KsPLSWIEEKGPGLKRNRyLsFHFKsGsLENVPNVGVNKNI
P53355	S734	EPSD\|PSP	DAPK1 DAPK	SFFRRRRPRLSSTNSSRFPPsPLASKPTVSVSINNLYPGCE
P53396	S481	Sugiyama	ACLY	ADEVAPAKKAKPAMPQDsVPsPRSLQGKSTTLFSRHTKAIV
P53621	S173	Sugiyama	COPA	ASLDQTVRVWDISGLRKKNLsPGAVEsDVRGITGVDLFGTT
P53634	T458	Sugiyama	CTSC CPPI	yFRIRRGtDECAIEsIAVAAtPIPKL_______________
P53805	S167	SIGNOR\|iPTMNet	RCAN1 ADAPT78 CSP1 DSC1 DSCR1	GSSHLAPPNPDKQFLIsPPAsPPVGWKQVEDAtPVINYDLL
P53992	S328	Sugiyama	SEC24C KIAA0079	sQPGPPQPLPPKRLDPDAIPsPIQVIEDDRNNRGTEPFVTG
P53999	S118	Sugiyama	SUB1 PC4 RPO2TC1	PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________
P54652	T39	Sugiyama	HSPA2	VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P54819	T89	Sugiyama	AK2 ADK2	DAGKLVSDEMVVELIEKNLEtPLCKNGFLLDGFPRTVRQAE
P55209	T62	Sugiyama	NAP1L1 NRP	MMQNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALK
P55211	T125	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CASP9 MCH6	NLtPVVLRPEIRKPEVLRPEtPRPVDIGSGGFGDVGALEsL
P55327	S40	PSP	TPD52	AGVNKSYLYLSPSGNSSPPGsPTLQKFGLLRTDPVPEEGED
P55795	S104	Sugiyama	HNRNPH2 FTP3 HNRPH2	EVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK
P55809	S509	Sugiyama	OXCT1 OXCT SCOT	LWEGLTVDDVQKSTGCDFAVsPKLMPMQQIAN_________
P56192	S209	SIGNOR\|PSP	MARS1 MARS	VLKQQGVLALRPYLQKQPQPsPAEGRAVTNEPEEEELATLs
P56192	S825	SIGNOR\|PSP	MARS1 MARS	LENDQIEsLRQRFGGGQAKtsPKPAVVEtVtTAKPQQIQAL
P56270	T72	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MAZ ZNF801	FFASQGCAQSPFQAAPAPPPtPQAPAAEPLQVDLLPVLAAA
P56693	T240	SIGNOR	SOX10	GSPMsDGNPEHPsGQSHGPPtPPTtPKTELQSGKADPKRDG
P56693	T244	SIGNOR	SOX10	sDGNPEHPsGQSHGPPtPPTtPKTELQSGKADPKRDGRSMG
P57740	S11	Sugiyama	NUP107	__________MDRsGFGEIssPVIREAEVTRTARKQSAQKR
P60174	S80	Sugiyama	TPI1 TPI	IAVAAQNCyKVTNGAFtGEIsPGMIKDCGAtWVVLGHsERR
P60174	T46	Sugiyama	TPI1 TPI	IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN
P60174	Y48	Sugiyama	TPI1 TPI	tLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQNCy
P60709	S300	Sugiyama	ACTB	NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P60709	S323	Sugiyama	ACTB	ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709	T201	Sugiyama	ACTB	AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709	T249	Sugiyama	ACTB	tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709	T318	Sugiyama	ACTB	VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709	T324	Sugiyama	ACTB	tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709	Y294	Sugiyama	ACTB	IHETTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQ
P60866	T6	Sugiyama	RPS20	_______________MAFKDtGKtPVEPEVAIHRIRITLTS
P61254	T8	Sugiyama	RPL26	_____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61586	S88	SIGNOR\|EPSD\|PSP	RHOA ARH12 ARHA RHO12	RLRPLSYPDTDVILMCFSIDsPDSLENIPEKWtPEVKHFCP
P61586	T100	SIGNOR\|EPSD\|PSP	RHOA ARH12 ARHA RHO12	ILMCFSIDsPDSLENIPEKWtPEVKHFCPNVPIILVGNKKD
P61604	S64	Sugiyama	HSPE1	AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD
P61604	T79	Sugiyama	HSPE1	EIQPVsVKVGDKVLLPEyGGtKVVLDDKDyFLFRDGDILGK
P61916	S40	Sugiyama	NPC2 HE1	EPVQFKDCGsVDGVIKEVNVsPCPtQPCQLSKGQSYSVNVT
P61978	S284	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP\|Sugiyama	HNRNPK HNRPK	MPPGRGGRPMPPSRRDyDDMsPRRGPPPPPPGRGGRGGsRA
P61978	S353	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	HNRNPK HNRPK	YDGMVGFSADETWDSAIDtWsPSEWQMAYEPQGGSGYDYSY
P61978	S81	Sugiyama	HNRNPK HNRPK	GGKNIKALRtDyNAsVsVPDssGPERILsISADIETIGEIL
P61981	S38	Sugiyama	YWHAG	ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS
P62070	S186	EPSD\|PSP	RRAS2 TC21	QAFHELVRVIRKFQEQECPPsPEPtRKEKDKKGCHCVIF__
P62081	S174	Sugiyama	RPS7	IKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEFQL
P62081	T172	Sugiyama	RPS7	RLIKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEF
P62195	T109	Sugiyama	PSMC5 SUG1	VHPEGKFVVDVDKNIDINDVtPNCRVALRNDsytLHKILPN
P62249	S9	Sugiyama	RPS16	____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62263	S137	Sugiyama	RPS14 PRO2640	RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______
P62263	T133	Sugiyama	RPS14 PRO2640	QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__
P62277	S14	Sugiyama	RPS13	_______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62714	S212	Sugiyama	PPP2CB	EGPMCDLLWSDPDDRGGWGIsPRGAGYTFGQDISETFNHAN
P62736	S325	Sugiyama	ACTA2 ACTSA ACTVS GIG46	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736	T251	Sugiyama	ACTA2 ACTSA ACTVS GIG46	tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736	T320	Sugiyama	ACTA2 ACTSA ACTVS GIG46	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736	T326	Sugiyama	ACTA2 ACTSA ACTVS GIG46	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62826	S150	Sugiyama	RAN ARA24 OK/SW-cl.81	KVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARKLIG
P62826	T21	Sugiyama	RAN ARA24 OK/SW-cl.81	MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA
P62942	S9	Sugiyama	FKBP1A FKBP1 FKBP12	____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG
P63000	T108	EPSD\|PSP	RAC1 TC25 MIG5	ASFENVRAKWYPEVRHHCPNtPIILVGTKLDLRDDKDTIEK
P63104	S28	Sugiyama	YWHAZ	QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63173	T14	Sugiyama	RPL38	_______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63261	S300	Sugiyama	ACTG1 ACTG	NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P63261	S323	Sugiyama	ACTG1 ACTG	ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261	T201	Sugiyama	ACTG1 ACTG	AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261	T249	Sugiyama	ACTG1 ACTG	tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261	T318	Sugiyama	ACTG1 ACTG	VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261	T324	Sugiyama	ACTG1 ACTG	tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261	Y294	Sugiyama	ACTG1 ACTG	IHETTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQ
P63267	S324	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267	T250	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267	T319	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267	T325	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P67775	S212	Sugiyama	PPP2CA	EGPMCDLLWSDPDDRGGWGIsPRGAGYTFGQDISETFNHAN
P68032	S325	Sugiyama	ACTC1 ACTC	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032	T251	Sugiyama	ACTC1 ACTC	tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032	T320	Sugiyama	ACTC1 ACTC	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032	T326	Sugiyama	ACTC1 ACTC	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133	S325	Sugiyama	ACTA1 ACTA	TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133	T251	Sugiyama	ACTA1 ACTA	tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133	T320	Sugiyama	ACTA1 ACTA	VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133	T326	Sugiyama	ACTA1 ACTA	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68363	T73	Sugiyama	TUBA1B	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363	T80	Sugiyama	TUBA1B	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363	Y83	Sugiyama	TUBA1B	PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P68400	S362	SIGNOR	CSNK2A1 CK2A1	GStPVSSANMMSGISSVPtPsPLGPLAGsPVIAAANPLGMP
P68400	T360	SIGNOR	CSNK2A1 CK2A1	PGGStPVSSANMMSGISSVPtPsPLGPLAGsPVIAAANPLG
P68431	S29	ELM	H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J	RKstGGKAPRKQLATKAARKsAPATGGVKKPHRyRPGtVAL
P78347	S210	Sugiyama	GTF2I BAP135 WBSCR6	EPKKHVGGRVMVtDADRsILsPGGsCGPIKVKTEPTEDSGI
P78347	S668	SIGNOR	GTF2I BAP135 WBSCR6	LVISyLPPGMASKINTKALQsPKRPRsPGsNsKVPEIEVtV
P78347	S674	SIGNOR	GTF2I BAP135 WBSCR6	PPGMASKINTKALQsPKRPRsPGsNsKVPEIEVtVEGPNNN
P78371	T475	Sugiyama	CCT2 99D8.1 CCTB	GYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGITE
P78536	T735	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	ADAM17 CSVP TACE	MLSSMDSASVRIIKPFPAPQtPGRLQPAPVIPSAPAAPKLD
P78543	S147	GPS6	BTG2 PC3	PLAASCGLLTCKNQVLLGRssPsKNYVMAVSS_________
P83731	S38	Sugiyama	RPL24	GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P84243	S29	SIGNOR	H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B	RKstGGKAPRKQLATKAARKsAPsTGGVKKPHRyRPGtVAL
P85037	S420	Sugiyama	FOXK1 MNF	RGVSCFRtPFGPLssRsAPAsPtHPGLMsPRsGGLQtPECL
P85037	S428	Sugiyama	FOXK1 MNF	PFGPLssRsAPAsPtHPGLMsPRsGGLQtPECLsREGsPIP
Q00613	S303	GPS6	HSF1 HSTF1	SIDERPLSSsPLVRVKEEPPsPPQsPRVEEAsPGRPssVDt
Q00613	S307	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	HSF1 HSTF1	RPLSSsPLVRVKEEPPsPPQsPRVEEAsPGRPssVDtLLsP
Q00613	S326	PSP	HSF1 HSTF1	QsPRVEEAsPGRPssVDtLLsPtALIDsILREsEPAPAsVT
Q00975	S446	SIGNOR	CACNA1B CACH5 CACNL1A5	NDLIHAEEGEDRFADLCAVGsPFARASLKSGKTESSSYFRR
Q01105	S133	Sugiyama	SET	DEEALHYLTRVEVtEFEDIKsGyRIDFyFDENPyFENKVLS
Q01105	S161	Sugiyama	SET	FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01196	S249	SIGNOR	RUNX1 AML1 CBFA2	stAFNPQPQSQMQDTRQIQPsPPWsyDQsyQyLGSIAsPsV
Q01196	S266	SIGNOR	RUNX1 AML1 CBFA2	IQPsPPWsyDQsyQyLGSIAsPsVHPAtPIsPGRASGMTTL
Q01196	S276	SIGNOR	RUNX1 AML1 CBFA2	QsyQyLGSIAsPsVHPAtPIsPGRASGMTTLSAELSSRLsT
Q01196	T273	SIGNOR	RUNX1 AML1 CBFA2	syDQsyQyLGSIAsPsVHPAtPIsPGRASGMTTLSAELSSR
Q01518	S431	Sugiyama	CAP1 CAP	NKTDGCHAYLSKNSLDCEIVsAKSSEMNVLIPTEGGDFNEF
Q01844	T422	Sugiyama	EWSR1 EWS	LDKETGKPKGDATVSyEDPPtAKAAVEWFDGKDFQGSKLKV
Q01844	T79	SIGNOR\|EPSD\|PSP	EWSR1 EWS	ATYGQTAYATSYGQPPTGYttPtAPQAYSQPVQGYGTGAYD
Q01860	S111	SIGNOR\|EPSD\|PSP	POU5F1 OCT3 OCT4 OTF3	ETsQPEGEAGVGVESNSDGAsPEPCTVtPGAVKLEKEKLEQ
Q01892	T56	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	SPIB	DsEGAPDSLWDWTVAPPVPAtPYEAFDPAAAAFSHPQAAQL
Q02447	S73	SIGNOR\|EPSD\|PSP	SP3	DTQPSPLALLAATCSKIGPPsPGDDEEEAAAAAGAPAAAGA
Q02548	S189	SIGNOR	PAX5	SVSTDSAGSSYSISGILGITsPSADTNKRKRDEGIQESPVP
Q02641	S161	SIGNOR	CACNB1 CACNLB1	NNDWWIGRLVKEGCEVGFIPsPVKLDSLRLLQEQKLRQNRL
Q02641	S348	SIGNOR	CACNB1 CACNLB1	HPAQLSKTSLAPIIVYIKITsPKVLQRLIKSRGKSQSKHLN
Q02750	T286	EPSD\|PSP	MAP2K1 MEK1 PRKMK1	PDAKELELMFGCQVEGDAAEtPPRPRtPGRPLssyGMDsRP
Q02750	T292	SIGNOR\|EPSD\|PSP	MAP2K1 MEK1 PRKMK1	ELMFGCQVEGDAAEtPPRPRtPGRPLssyGMDsRPPMAIFE
Q02750	T386	SIGNOR	MAP2K1 MEK1 PRKMK1	AEEVDFAGWLCstIGLNQPstPtHAAGV_____________
Q02790	S15	Sugiyama	FKBP4 FKBP52	______MTAEEMKAtEsGAQsAPLPMEGVDIsPKQDEGVLK
Q02952	S283	Sugiyama	AKAP12 AKAP250	EECKEEGEEKQEKEPSKsAEsPtsPVtsETGstFKKFFTQG
Q02952	S286	Sugiyama	AKAP12 AKAP250	KEEGEEKQEKEPSKsAEsPtsPVtsETGstFKKFFTQGWAG
Q03060	S277	SIGNOR\|PSP	CREM	APTAALPQGVVMAAsPGSLHsPQQLAEEATRKRELRLMKNR
Q04637	S1231	Sugiyama	EIF4G1 EIF4F EIF4G EIF4GI	tEDRDRGRDAVKREAALPPVsPLKAALsEEELEKKsKAIIE
Q04637	S198	Sugiyama	EIF4G1 EIF4F EIF4G EIF4GI	KTIRIRDPNQGGKDITEEIMsGARtAstPtPPQtGGGLEPQ
Q05209	S571	EPSD\|PSP	PTPN12	sEGNssDINYQTRKtVsLtPsPttQVEtPDLVDHDNtsPLF
Q05469	T891	SIGNOR\|iPTMNet	LIPE	LKNLTLRDLSLRGNSETSSDtPEMSLSAETLSPSTPSDVNF
Q05682	S759	SIGNOR\|EPSD\|PSP	CALD1 CAD CDM	KVGVSsRINEWLTKtPDGNKsPAPKPSDLRPGDVssKRNLW
Q05682	S789	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CALD1 CAD CDM	PGDVssKRNLWEKQsVDKVtsPTKV________________
Q06210	S103	Sugiyama	GFPT1 GFAT GFPT	IEFDVHLGIAHTRWATHGEPsPVNSHPQRSDKNNEFIVIHN
Q06413	S387	ELM	MEF2C	GACTSTHLSQSSNLSLPSTQsLNIKSEPVsPPRDRTTtPSR
Q06830	S152	Sugiyama	PRDX1 PAGA PAGB TDPX2	IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV
Q06830	T143	Sugiyama	PRDX1 PAGA PAGB TDPX2	EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF
Q07021	T165	Sugiyama	C1QBP GC1QBP HABP1 SF2P32	GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD
Q07157	S1180	Sugiyama	TJP1 ZO1	QPAPGyDtHGRLRPEAQPHPsAGPKPAEsKQyFEQysRsyE
Q07157	S1617	Sugiyama	TJP1 ZO1	AEKPKyQINNISTVPKAIPVsPsAVEEDEDEDGHTVVATAR
Q07820	T163	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MCL1 BCL2L3	LLELVGEsGNNtstDGsLPstPPPAEEEEDELYRQSLEIIS
Q07820	T92	EPSD\|PSP	MCL1 BCL2L3	DSRRVARPPPIGAEVPDVTAtPARLLFFAPTRRAAPLEEME
Q07866	S460	SIGNOR\|Sugiyama	KLC1 KLC KNS2	QKDGTsFGEyGGWyKACKVDsPtVTTtLKNLGALyRRQGKF
Q07869	S12	SIGNOR\|ELM\|iPTMNet\|EPSD	PPARA NR1C1 PPAR	_________MVDTEsPLCPLsPLEAGDLEsPLSEEFLQEMG
Q07869	S21	SIGNOR\|ELM\|iPTMNet	PPARA NR1C1 PPAR	MVDTEsPLCPLsPLEAGDLEsPLSEEFLQEMGNIQEISQSI
Q07889	S1132	SIGNOR	SOS1	PFHSSNDTVFIQVTLPHGPRsAsVSSISLTKGTDEVPVPPP
Q07889	S1167	SIGNOR	SOS1	VPVPPPVPPRRRPEsAPAEssPSKIMSKHLDsPPAIPPRQP
Q07889	S1178	SIGNOR	SOS1	RPEsAPAEssPSKIMSKHLDsPPAIPPRQPTSKAYsPRYsI
Q07889	S1193	SIGNOR	SOS1	SKHLDsPPAIPPRQPTSKAYsPRYsISDRTsIsDPPEsPPL
Q07889	S1197	SIGNOR	SOS1	DsPPAIPPRQPTSKAYsPRYsISDRTsIsDPPEsPPLLPPR
Q07960	S51	Sugiyama	ARHGAP1 CDC42GAP RHOGAP1	KNWPsDEMPDFPKsDDsKsssPELVtHLKWDDPyyDIARHQ
Q08499	S715	SIGNOR	PDE4D DPDE3	QDILDTLEDNREWYQstIPQsPsPAPDDPEEGRQGQTEKFQ
Q08AD1	S673	Sugiyama	CAMSAP2 CAMSAP1L1 KIAA1078	DASKFLQDyDIRTGNTREALsPCPsTVsTKSQPGSSAssss
Q08J23	S743	Sugiyama	NSUN2 SAKI TRM4	AstGQPDNDVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGV
Q09472	S1038	SIGNOR\|PSP	EP300 P300	ELKTEIKEEEDQPstsAtQssPAPGQSKKKIFKPEELRQAL
Q09472	S2039	SIGNOR\|PSP	EP300 P300	AQHGQPLNMAPQPGLGQVGIsPLKPGTVSQQALQNLLRTLR
Q09472	S2279	SIGNOR	EP300 P300	AYQQRLLQQQMGSPVQPNPMsPQQHMLPNQAQSPHLQGQQI
Q09472	S2315	SIGNOR	EP300 P300	QGQQIPNSLSNQVRsPQPVPsPRPQsQPPHssPsPRMQPQP
Q09472	S2366	SIGNOR	EP300 P300	SPHPGLVAAQANPMEQGHFAsPDQNSMLSQLASNPGMANLH
Q09666	S93	Sugiyama	AHNAK PM227	LLNTMGHHTVGLKLHRKGDRsPEPGQtWtREVFssCssEVV
Q09666	T4100	Sugiyama	AHNAK PM227	VDVNLPKADIDVsGPKVDIDtPDIDIHGPEGKLKGPKFKMP
Q09666	T4564	Sugiyama	AHNAK PM227	LEGDLKGPKVDVKGPKVGIDtPDIDIHGPEGKLKGPKFKMP
Q12772	S432	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SREBF2 BHLHD2 SREBP2	LVDNEVDLKIEDFNQNVLLMsPPASDSGSQAGFSPYSIDSE
Q12772	S455	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SREBF2 BHLHD2 SREBP2	ASDSGSQAGFSPYSIDSEPGsPLLDDAKVKDEPDsPPVALG
Q12774	S445	Sugiyama	ARHGEF5 TIM	ASYLMTQIPGTQTESRAEELsPAALsPsLEPIRCSHQPISL
Q12774	S450	Sugiyama	ARHGEF5 TIM	TQIPGTQTESRAEELsPAALsPsLEPIRCSHQPISLLGsFL
Q12792	S143	Sugiyama	TWF1 PTK9	GTVKEDVSLHGYKKyLLsQssPAPLtAAEEELRQIKINEVQ
Q12800	S291	SIGNOR	TFCP2 LSF SEF	TTILTECSPWPEITYVNNsPsPGFNSSHSSFSLGEGNGsPN
Q12800	S309	SIGNOR	TFCP2 LSF SEF	sPsPGFNSSHSSFSLGEGNGsPNHQPEPPPPVTDNLLPTTT
Q12929	S625	SIGNOR	EPS8	tIQKQRMEYGPRPADtPPAPsPPPtPAPVPVPLPPstPAPV
Q12931	S511	EPSD\|PSP\|Sugiyama	TRAP1 HSP75 HSPC5	RAGtRNIyyLCAPNRHLAEHsPyyEAMKKKDTEVLFCFEQF
Q12931	S568	Sugiyama	TRAP1 HSP75 HSPC5	ISVETDIVVDHYKEEKFEDRsPAAECLSEKETEELMAWMRN
Q13033	S229	Sugiyama	STRN3 GS2NA SG2NA	SEPNGsVETKNLEQILNGGEsPKQKGQEIKRSSGDVLETFN
Q13115	S386	PSP	DUSP4 MKP2 VH2	FSFPVSVGVHSAPSSLPYLHsPITTsPSC____________
Q13115	S391	PSP	DUSP4 MKP2 VH2	SVGVHSAPSSLPYLHsPITTsPSC_________________
Q13127	S861	PSP	REST NRSF XBR	GLVPVKDSWLLKESVstEDLsPPsPPLPKENLREEASGDQK
Q13127	S864	PSP	REST NRSF XBR	PVKDSWLLKESVstEDLsPPsPPLPKENLREEASGDQKLLN
Q13153	T292	SIGNOR	PAK1	RFEKIGQGASGTVyTAMDVAtGQEVAIKQMNLQQQPKKELI
Q13164	T733	EPSD\|PSP	MAPK7 BMK1 ERK5 PRKM7	VTQQLSKsQVEDPLPPVFsGtPKGSGAGYGVGFDLEEFLNQ
Q13200	S16	Sugiyama	PSMD2 TRAP2	_____MEEGGRDKAPVQPQQsPAAAPGGtDEKPsGKERRDA
Q13228	S53	Sugiyama	SELENBP1 SBP	yRNtGtEAPDyLATVDVDPKsPQyCQVIHRLPMPNLKDELH
Q13263	Y755	Sugiyama	TRIM28 KAP1 RNF96 TIF1B	GGTLDLTLIRARLQEKLsPPyssPQEFAQDVGRMFKQFNKL
Q13283	S230	Sugiyama	G3BP1 G3BP	IQEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFs
Q13283	S231	Sugiyama	G3BP1 G3BP	QEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsW
Q13283	S232	Sugiyama	G3BP1 G3BP	EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA
Q13283	T241	Sugiyama	G3BP1 G3BP	ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP
Q13322	S150	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	GRB10 GRBIR KIAA0207	FRtssLPAIPNPFPELCGPGsPPVLtPGSLPPSQAAAKQDV
Q13322	S418	GPS6\|SIGNOR	GRB10 GRBIR KIAA0207	KYGMLLYQNYRIPQQRKALLsPFstPVRsVsENsLVAMDFS
Q13322	S476	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	GRB10 GRBIR KIAA0207	LEEGHAWRKRSTRMNILGsQsPLHPstLSTVIHRTQHWFHG
Q13362	S337	SIGNOR	PPP2R5C KIAA0044	PSEFVKIMEPLFRQLAKCVssPHFQVAERALYYWNNEYIMS
Q13424	S193	ELM	SNTA1 SNT1	SPYFKNStGGtsVGWDsPPAsPLQRQPssPGPTPRNFSEAK
Q13424	S201	ELM	SNTA1 SNT1	GGtsVGWDsPPAsPLQRQPssPGPTPRNFSEAKHMSLKMAY
Q13428	T1014	Sugiyama	TCOF1	ARssssEsEDEDVIPAtQCLtPGIRTNVVTMPTAHPRIAPK
Q13480	S381	GPS6\|SIGNOR\|iPTMNet	GAB1	SIPRTAsDTDssyCIPtAGMsPSRSNtIstVDLNKLRKDAs
Q13480	S454	GPS6\|SIGNOR\|iPTMNet	GAB1	TVGSVssEELDENyVPMNPNsPPRQHSSSFTEPIQEANyVP
Q13480	S551	SIGNOR	GAB1	PAPLEIKPLPEWEELQAPVRsPITRSFARDSSRFPMsPRPD
Q13480	S567	SIGNOR	GAB1	APVRsPITRSFARDSSRFPMsPRPDSVHSTTSSSDsHDSEE
Q13480	S582	GPS6	GAB1	SRFPMsPRPDSVHSTTSSSDsHDSEENyVPMNPNLsSEDPN
Q13480	S597	GPS6\|SIGNOR\|iPTMNet	GAB1	TSSSDsHDSEENyVPMNPNLsSEDPNLFGSNSLDGGSSPMI
Q13480	T312	GPS6\|SIGNOR\|iPTMNet	GAB1	GTSSVETQMRHVsIsyDIPPtPGNtyQIPRTFPEGTLGQTS
Q13480	T476	GPS6\|SIGNOR\|iPTMNet	GAB1	PRQHSSSFTEPIQEANyVPMtPGTFDFSSFGMQVPPPAHMG
Q13485	T277	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SMAD4 DPC4 MADH4	PATYHHNStTTWtGSRtAPYtPNLPHHQNGHLQHHPPMPPH
Q13501	S272	Sugiyama	SQSTM1 ORCA OSIL	GIEVDIDVEHGGKRsRLtPVsPEssstEEKsssQPssCCsD
Q13501	T269	Sugiyama	SQSTM1 ORCA OSIL	sPLGIEVDIDVEHGGKRsRLtPVsPEssstEEKsssQPssC
Q13509	S168	Sugiyama	TUBB3 TUBB4	GTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
Q13509	S172	Sugiyama	TUBB3 TUBB4	ISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSIHQL
Q13509	T166	Sugiyama	TUBB3 TUBB4	GMGTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT
Q13526	S115	Sugiyama	PIN1	KIKSGEEDFEsLAsQFSDCSsAKARGDLGAFsRGQMQKPFE
Q13541	S65	GPS6\|EPSD\|PSP	EIF4EBP1	ttPGGtRIIyDRKFLMECRNsPVtKtPPRDLPtIPGVtsPs
Q13614	S58	EPSD\|PSP	MTMR2 KIAA1073	HTKSASVVssDSIStSADNFsPDLRVLRESNKLAEMEEPPL
Q13950	S24	EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	NSLFSTVTPCQQNFFWDPSTsRRFsPPSSSLQPGKMSDVsP
Q13950	S275	EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	PSMRVGVPPQNPRPsLNSAPsPFNPQGQSQITDPRQAQssP
Q13950	S28	EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	STVTPCQQNFFWDPSTsRRFsPPSSSLQPGKMSDVsPVVAA
Q13950	S294	SIGNOR\|EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	PsPFNPQGQSQITDPRQAQssPPWsyDQSYPSYLSQMTsPs
Q13950	S312	SIGNOR\|EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	QssPPWsyDQSYPSYLSQMTsPsIHSTTPLSSTRGTGLPAI
Q13950	S314	EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	sPPWsyDQSYPSYLSQMTsPsIHSTTPLSSTRGTGLPAITD
Q13950	S340	EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	PLSSTRGTGLPAITDVPRRIsDDDtAtsDFCLWPSTLSKKS
Q13950	S43	EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	TsRRFsPPSSSLQPGKMSDVsPVVAAQQQQQQQQQQQQQQQ
Q13950	S503	EPSD\|PSP	RUNX2 AML3 CBFA1 OSF2 PEBP2A	LNPNLPNQNDGVDADGsHSSsPTVLNSSGRMDESVWRPY__
Q14005	S845	GPS6\|SIGNOR\|EPSD	IL16	HLGSHIRASSSSSSIRQRIssFETFGSSQLPDKGAQRLsLQ
Q14103	T193	Sugiyama	HNRNPD AUF1 HNRPD	KAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVESIEL
Q14157	S416	Sugiyama	UBAP2L KIAA0144 NICE4	tQsPsLVQYDLKNPsDsAVHsPFtKRQAFtPsstMMEVFLQ
Q14157	S477	Sugiyama	UBAP2L KIAA0144 NICE4	PsKstsAPQMsPGssDNQsssPQPAQQKLKQQKKKAsLTSK
Q14157	S859	Sugiyama	UBAP2L KIAA0144 NICE4	FPtPttPLtGRDGsLAsNPysGDLtKFGRGDASSPAPATTL
Q14160	S1439	Sugiyama	SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL	DGETLGEEEQEDEQPPWAsPsPtsRQsPAsPPPLGGGAPVR
Q14160	S1448	SIGNOR\|Sugiyama	SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL	QEDEQPPWAsPsPtsRQsPAsPPPLGGGAPVRTAKAERRHQ
Q14160	S504	Sugiyama	SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL	MKRSIEGRRsEACPCQPDsGsPLPAEEEKRLsAESGLSEDS
Q14160	S853	SIGNOR	SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL	DysPRERRGGGLRLPLLPPEsPGPLRQRHVACLARSERGLG
Q14204	S2410	Sugiyama	DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325	GEDEAQRRRKGKEDEGEEAAsPMLQIQRDAATIMQPYFTSN
Q14204	S3082	Sugiyama	DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325	LHVVFTMNPSSEGLKDRAAtsPALFNRCVLNWFGDWSTEAL
Q14247	S405	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP\|Sugiyama	CTTN EMS1	EEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVyEDAA
Q14247	S418	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP\|Sugiyama	CTTN EMS1	KtQtPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVs
Q14247	Y421	Sugiyama	CTTN EMS1	tPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVsGtE
Q14566	S507	Sugiyama	MCM6	AGVKATLNARTsILAAANPIsGHyDRSKSLKQNINLSAPIM
Q14568	S52	Sugiyama	HSP90AA2P HSP90AA2 HSPC2 HSPCAL3	LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS
Q14684	T708	Sugiyama	RRP1B KIAA0179	LNRNMtAEFKKTDKsILVsPtGPsRVAFDPEQKPLHGVLKt
Q14761	S163	PSP	PTPRCAP LPAP	VPVRAEEARDsDtEGDLVLGsPGPAsAGGsAEALLsDLHAF
Q14790	S387	SIGNOR\|EPSD\|PSP	CASP8 MCH5	KGIPVETDSEEQPyLEMDLSsPQTRYIPDEADFLLGMATVN
Q14934	S676	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NFATC4 NFAT3	KRVSRPVQVYFYVSNGRRKRsPTQSFRFLPVICKEEPLPDS
Q14980	S1757	Sugiyama	NUMA1 NMP22 NUMA	ITSKLPRtQPDGtsVPGEPAsPIsQRLPPKVEsLEsLyFtP
Q15003	S81	Sugiyama	NCAPH BRRN BRRN1 CAPH KIAA0074	EKERLQRRRsRVFDLQFstDsPRLLAsPsSRsIDIsATIPK
Q15007	S306	PSP	WTAP KIAA0105	RtsGSGFHREGNtTEDDFPssPGNGNKSSNSSEERTGRGGS
Q15007	S341	PSP	WTAP KIAA0105	TGRGGSGYVNQLSAGYESVDsPtGSENSLTHQSNDtDsSHD
Q15007	T148	PSP	WTAP KIAA0105	LEQTKDKLEQAQNELSAWKFtPDSQTGKKLMAKCRMLIQEN
Q15046	S207	SIGNOR\|EPSD\|PSP	KARS1 KARS KIAA0070	NPGKTKKGELSIIPYEITLLsPCLHMLPHLHFGLKDKETRY
Q15256	T361	SIGNOR	PTPRR ECPTP PTPRQ	VSLTLDMSSLGNIEPFVSIPtPREKVAMEYLQSASRILTRS
Q15293	T76	Sugiyama	RCN1 RCN	FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD
Q15303	S1051	SIGNOR\|PSP	ERBB4 HER4	PPPIyTSRARIDSNRsEIGHsPPPAyTPMSGNQFVyRDGGF
Q15303	T699	SIGNOR\|PSP	ERBB4 HER4	SIKKKRALRRFLETELVEPLtPSGTAPNQAQLRILKETELK
Q15366	S173	SIGNOR\|PSP	PCBP2	QSIIECVKQICVVMLEtLsQsPPKGVtIPyRPKPsssPVIF
Q15366	S189	SIGNOR\|PSP	PCBP2	tLsQsPPKGVtIPyRPKPsssPVIFAGGQDRYSTGSDSASF
Q15366	S272	SIGNOR\|PSP	PCBP2	QQSHFPMTHGNTGFsGIEsssPEVKGYWGLDASAQTTSHEL
Q15366	T213	SIGNOR\|PSP	PCBP2	FAGGQDRYSTGSDSASFPHTtPSMCLNPDLEGPPLEAYTIQ
Q15418	S221	SIGNOR	RPS6KA1 MAPKAPK1A RSK1	IKLTDFGLSKEAIDHEKKAysFCGtVEYMAPEVVNRQGHSH
Q15418	S363	SIGNOR\|ELM	RPS6KA1 MAPKAPK1A RSK1	AQPDDTFYFDTEFTSRtPKDsPGIPPsAGAHQLFRGFsFVA
Q15418	S380	SIGNOR	RPS6KA1 MAPKAPK1A RSK1	PKDsPGIPPsAGAHQLFRGFsFVAtGLMEDDGKPRAPQAPL
Q15418	S732	SIGNOR	RPS6KA1 MAPKAPK1A RSK1	PQLKPIESSILAQRRVRKLPsTTL_________________
Q15418	T359	SIGNOR\|ELM	RPS6KA1 MAPKAPK1A RSK1	KPAVAQPDDTFYFDTEFTSRtPKDsPGIPPsAGAHQLFRGF
Q15418	T573	SIGNOR	RPS6KA1 MAPKAPK1A RSK1	LRICDFGFAKQLRAENGLLMtPCytANFVAPEVLKRQGYDE
Q15596	S736	EPSD\|PSP	NCOA2 BHLHE75 SRC2 TIF2	sQESSSTAPGsEVtIKQEPVsPKKKENALLRYLLDKDDTKD
Q15599	S43	Sugiyama	NHERF2 SLC9A3R2	FHLHGEKGRRGQFIRRVEPGsPAEAAALRAGDRLVEVNGVN
Q15642	S495	Sugiyama	TRIP10 CIP4 STOT STP	VLsNRGDsLSRHARPPDPPAsAPPDsssNsAsQDtKESSEE
Q15648	T1032	SIGNOR\|EPSD\|PSP	MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2	RKKADtEGKsPsHssSNRPFtPPtSTGGSKsPGsAGRsQtP
Q15648	T1457	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2	sGstPKHERGsPsHsKsPAytPQNLDsEsEsGSSIAEKsyQ
Q15672	S68	SIGNOR\|EPSD\|PSP	TWIST1 BHLHA38 TWIST	GGAGPGGAAGGGVGGGDEPGsPAQGKRGKKSAGCGGGGGAG
Q15744	T74	ELM	CEBPE	LSDLFAVKPAPEARGLKGPGtPAFPHYLPPDPRPFAYPPHT
Q15746	S16	ELM	MYLK MLCK MLCK1 MYLK1	_____MGDVKLVASSHIsKTsLsVDPSRVDSMPLTEAPAFI
Q15746	S1779	EPSD\|PSP	MYLK MLCK MLCK1 MYLK1	ssMAMISGLSGRKsstGsPtsPLNAEKLEsEEDVsQAFLEA
Q15746	S947	PSP	MYLK MLCK MLCK1 MYLK1	ANLQRQVKPKTVSEEERKVHsPQQVDFRSVLAKKGTSKTPV
Q15746	T978	PSP	MYLK MLCK MLCK1 MYLK1	AKKGTSKTPVPEKVPPPKPAtPDFRSVLGGKKKLPAENGSS
Q15750	S438	PSP	TAB1 MAP3K7IP1	VNGAHsASTLDEAtPTLTNQsPTLTLQSTNTHTQssSSssD
Q15788	S1185	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NCOA1 BHLHE74 SRC1	QQFPYPPNYGTNPGtPPASTsPFSQLAANPEASLANRNSMV
Q15788	T1179	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NCOA1 BHLHE74 SRC1	LPQGAPQQFPYPPNYGTNPGtPPASTsPFSQLAANPEASLA
Q15796	S245	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SMAD2 MADH2 MADR2	YISEDGETSDQQLNQsMDtGsPAELsPTTLsPVNHsLDLQP
Q15796	S250	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SMAD2 MADH2 MADR2	GETSDQQLNQsMDtGsPAELsPTTLsPVNHsLDLQPVTYSE
Q15796	S255	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SMAD2 MADH2 MADR2	QQLNQsMDtGsPAELsPTTLsPVNHsLDLQPVTYSEPAFWC
Q15796	T220	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SMAD2 MADH2 MADR2	IPENTNFPAGIEPQSNYIPEtPPPGYISEDGETSDQQLNQs
Q15796	T8	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SMAD2 MADH2 MADR2	_____________MssILPFtPPVVKRLLGWKKsAGGSGGA
Q15831	S428	SIGNOR	STK11 LKB1 PJS	GRAPNPARKACSASSKIRRLsACKQQ_______________
Q16204	S240	Sugiyama	CCDC6 D10S170 TST1	RMDKLEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMR
Q16204	S244	SIGNOR\|iPTMNet\|Sugiyama	CCDC6 D10S170 TST1	LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF
Q16254	S244	EPSD\|PSP	E2F4	TPPPLPKPALAQSQEASRPNsPQLTPTAVPGSAEVQGMAGP
Q16254	S384	EPSD\|PSP	E2F4	SSELLEELMSSEVFAPLLRLsPPPGDHDYIYNLDESEGVCD
Q16559	S100	EPSD\|PSP	TAL2 BHLHA19	QGPHLPGLEDRTLLENYQVPsPGPSHHIP____________
Q16584	S705	EPSD\|PSP	MAP3K11 MLK3 PTK1 SPRK	PCPTEPPPsPLICFSLKtPDsPPtPAPLLLDLGIPVGQRsA
Q16584	S758	EPSD\|PSP	MAP3K11 MLK3 PTK1 SPRK	tVsPPPGTSRsAPGtPGTPRsPPLGLIsRPRPsPLRSRIDP
Q16630	T157	Sugiyama	CPSF6 CFIM68	SKKLMDLLPKRELHGQNPVVtPCNKQFLsQFEMQSRKTTQS
Q16658	S127	Sugiyama	FSCN1 FAN1 HSN SNL	AHRRYFGGtEDRLsCFAQtVsPAEKWSVHIAMHPQVNIYSV
Q16659	S189	ELM	MAPK6 ERK3 PRKM6	IGDFGLARIMDPHYSHKGHLsEGLVTKWYRSPRLLLSPNNY
Q16665	S641	SIGNOR	HIF1A BHLHE78 MOP1 PASD8	TDELKTVTKDRMEDIKILIAsPsPTHIHKETTSATSsPYRD
Q16665	S643	SIGNOR	HIF1A BHLHE78 MOP1 PASD8	ELKTVTKDRMEDIKILIAsPsPTHIHKETTSATSsPYRDTQ
Q16690	S346	EPSD\|PSP	DUSP5 VH3	PPSCQGEAAGSSLIGHLQTLsPDMQGAYCTFPASVLAPVPT
Q16690	S376	EPSD\|PSP	DUSP5 VH3	FPASVLAPVPTHSTVSELSRsPVATATSC____________
Q16690	T321	EPSD\|PSP	DUSP5 VH3	SPNFGFMGQLLQYESEILPStPNPQPPSCQGEAAGSSLIGH
Q16828	S159	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	DUSP6 MKP3 PYST1	FQAEFSLHCETNLDGSCSSSsPPLPVLGLGGLRISsDSssD
Q16828	S174	EPSD\|PSP	DUSP6 MKP3 PYST1	SCSSSsPPLPVLGLGGLRISsDSssDIEsDLDRDPNSATDS
Q16828	S197	SIGNOR\|EPSD\|PSP	DUSP6 MKP3 PYST1	ssDIEsDLDRDPNSATDSDGsPLSNSQPSFPVEILPFLYLG
Q16828	S300	EPSD\|PSP	DUSP6 MKP3 PYST1	DEARGKNCGVLVHCLAGISRsVTVTVAYLMQKLNLSMNDAY
Q16881	T413	Sugiyama	TXNRD1 GRIM12 KDRF	HGIKFIRQFVPIKVEQIEAGtPGRLRVVAQSTNSEEIIEGE
Q2M1V0	S183	PSP	ISX RAXLX	LDVAGPTWTSTALRRLAPPTsCCPSAQDQLASAWFPAWITL
Q2M1Z3	T789	SIGNOR	ARHGAP31 CDGAP KIAA1204	VEVGGPGNLsPPLPPAPPPPtPLEESTPVLLSKGGPEREDS
Q53EL6	S94	Sugiyama	PDCD4 H731	GDsVsDsGsDALRSGLtVPtsPKGRLLDRRSRSGKGRGLPK
Q53GS7	S88	PSP	GLE1 GLE1L	ETSPSSTSASALDQPSFVPKsPDAssAFsPAsPAtPNGTKG
Q53GS7	S92	PSP	GLE1 GLE1L	SSTSASALDQPSFVPKsPDAssAFsPAsPAtPNGTKGKDES
Q53GS7	S93	PSP	GLE1 GLE1L	STSASALDQPSFVPKsPDAssAFsPAsPAtPNGTKGKDESQ
Q53GS7	S99	PSP	GLE1 GLE1L	LDQPSFVPKsPDAssAFsPAsPAtPNGTKGKDESQHTESMV
Q53GS7	T102	PSP	GLE1 GLE1L	PSFVPKsPDAssAFsPAsPAtPNGTKGKDESQHTESMVLQS
Q562R1	T250	Sugiyama	ACTBL2	RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q58FF7	S370	Sugiyama	HSP90AB3P HSP90BC	KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q5JSH3	S96	Sugiyama	WDR44 RPH11	QLEDDsLDSKGKELsDQAtAsPIVARTDLSNIPGLLAIDQV
Q5SW79	S223	Sugiyama	CEP170 FAM68A KAB KIAA0470	KNHEAGTSGCGIDAKQVEEQsAAANEEVLFPFCREPsYFEI
Q5T447	T157	SIGNOR	HECTD3	EGWLLVCRPAEGGARLVPIDtPNHLQRQQQLFGVDYRPVLR
Q5T4S7	S178	Sugiyama	UBR4 KIAA0462 KIAA1307 RBAF600	AKLPQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLT
Q5T4S7	S181	Sugiyama	UBR4 KIAA0462 KIAA1307 RBAF600	PQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLTSVF
Q5T6F2	S432	Sugiyama	UBAP2 KIAA1491	PPTSQSSVLSHLDFKsQPEPsPVLSQLsQRQQHQSQAVTVP
Q66K74	S759	Sugiyama	MAP1S BPY2IP1 C19orf5 MAP8 VCY2IP1	LVsPCEFEHRKAVPMAPAPAsPGssNDssARsQERAGGLGA
Q68CZ2	S840	Sugiyama	TNS3 TEM6 TENS1 TPP	tPGyPQDLDIIDGRILSSKEsMCStPAFPVsPEtPyVKTAL
Q68CZ2	T844	Sugiyama	TNS3 TEM6 TENS1 TPP	PQDLDIIDGRILSSKEsMCStPAFPVsPEtPyVKTALRHPP
Q68CZ2	T853	Sugiyama	TNS3 TEM6 TENS1 TPP	RILSSKEsMCStPAFPVsPEtPyVKTALRHPPFsPPEPPLs
Q68CZ2	Y855	Sugiyama	TNS3 TEM6 TENS1 TPP	LSSKEsMCStPAFPVsPEtPyVKTALRHPPFsPPEPPLssP
Q69YN4	S1579	Sugiyama	VIRMA KIAA1429 MSTP054	CCSDFDLHSELERsFLsEPssPGRtKTTKGFKLGKHKHETF
Q6FI81	S272	Sugiyama	CIAPIN1 CUA001 PRO0915	GLAEELEKEKSREQMSSQPKsACGNCyLGDAFRCAsCPyLG
Q6FI81	T136	Sugiyama	CIAPIN1 CUA001 PRO0915	CSALTLSGLVEVKELQREPLtPEEVQSVREHLGHESDNLLF
Q6P2E9	S844	Sugiyama	EDC4 HEDLS	sQVWPTAPDITREtCStLAEsPRNGLQEKHKsLAFHRPPYH
Q6PKG0	S521	Sugiyama	LARP1 KIAA0731 LARP	NCPEFVPRQHYQKEtEsAPGsPRAVtPVPtKTEEVSNLKTL
Q6PKG0	S774	Sugiyama	LARP1 KIAA0731 LARP	LFGAPEPstIARsLPttVPEsPNyRNtRtPRtPRtPQLKDS
Q6PKG0	T526	Sugiyama	LARP1 KIAA0731 LARP	VPRQHYQKEtEsAPGsPRAVtPVPtKTEEVSNLKTLPKGLs
Q6S5L8	T159	SIGNOR	SHC4 SHCD UNQ6438/PRO21364	RSGTAPPPQQDLVGHRAtALtPDSCPLPGPGEPTLRSRQDR
Q6S8J3	T949	Sugiyama	POTEE A26C1A POTE2	tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6ULP2	S151	Sugiyama	AFTPH AFTH	PGNLNKVVEQRQNVGTLESFsPGDFRTNMNVVHQNKQLESC
Q6UUV7	S391	PSP	CRTC3 TORC3	NPsLstTNLSGPSRRRQPPVsPLtLsPGPEAHQGFSRQLss
Q6VN20	S365	Sugiyama	RANBP10 KIAA1464	DSEVRSLSSRsPKsQDsyPGsPsLsPRHGPsssHMHNTGAD
Q6VN20	S369	Sugiyama	RANBP10 KIAA1464	RSLSSRsPKsQDsyPGsPsLsPRHGPsssHMHNTGADsPsC
Q6ZMR3	S161	Sugiyama	LDHAL6A LDHL2	DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3	S167	Sugiyama	LDHAL6A LDHL2	AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71U36	T73	Sugiyama	TUBA1A TUBA3	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36	T80	Sugiyama	TUBA1A TUBA3	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36	Y83	Sugiyama	TUBA1A TUBA3	PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q71UM5	T74	Sugiyama	RPS27L	VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
Q7L2J0	S216	Sugiyama	MEPCE BCDIN3	NLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPKDIt
Q7L2J0	S217	Sugiyama	MEPCE BCDIN3	LNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPKDItD
Q7L2J0	T213	Sugiyama	MEPCE BCDIN3	DPLNLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPK
Q7Z2W4	T273	Sugiyama	ZC3HAV1 ZC3HDC2 PRO1677	FFQGsQEFLASASAsAERsCtPsPDQIsHRAsLEDAPVDDL
Q7Z3J3	T1475	Sugiyama	RGPD4 RGP4	DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
Q7Z417	S692	Sugiyama	NUFIP2 KIAA1321 PIG1	IWNLQKQDPKRIItyNEAMDsPDQ_________________
Q7Z5K2	S221	Sugiyama	WAPL FOE KIAA0261 WAPAL	AsEIKETNDTWNSQFGKRPEsPsEIsPIKGsVRTGLFEWDN
Q7Z5K2	S226	Sugiyama	WAPL FOE KIAA0261 WAPAL	ETNDTWNSQFGKRPEsPsEIsPIKGsVRTGLFEWDNDFEDI
Q86U44	S43	SIGNOR\|PSP	METTL3 MTA70	QRRRKQDsGHLDLRNPEAALsPtFRsDsPVPtAPtsGGPKP
Q86U44	S50	SIGNOR\|PSP	METTL3 MTA70	sGHLDLRNPEAALsPtFRsDsPVPtAPtsGGPKPstAsAVP
Q86U44	S525	SIGNOR\|PSP	METTL3 MTA70	AEVRSTSHKPDEIyGMIERLsPGTRKIELFGRPHNVQPNWI
Q86UC2	T286	EPSD\|PSP	RSPH3 RSHL2 RSP3	DRIIEVDMECQTDAFLDRPPtPLFIPAKTGKDVATQILEGE
Q86UR1	S282	SIGNOR\|EPSD\|PSP	NOXA1 P51NOX	STAYQEQRPQVEQVGKQAPLsPGLPAMGGPGPGPCEDPAGA
Q86UY5	S357	Sugiyama	FAM83A TSGP	GRSAGSHPGTRsVsAssGPCsPAAPHPPPPPRFQPHQGPWG
Q86VP6	S376	Sugiyama	CAND1 KIAA0829 TIP120 TIP120A	CLDAVVSTRHEMLPEFyKTVsPALISRFKEREENVKADVFH
Q86W92	S1001	Sugiyama	PPFIBP1 KIAA1230	NLTHMLKEDDMFKDFAARsPsAsItDEDsNV__________
Q86YP4	S114	Sugiyama	GATAD2A	SERRPPsPDVIVLsDNEQPssPRVNGLttVALKETSTEALM
Q8IWA4	T562	SIGNOR	MFN1	QRVLLGLSEPIFQLPRSLAStPTAPTTPATPDNASQEELMI
Q8IWX8	S822	Sugiyama	CHERP DAN26 SCAF6	SKSYSPGRRRRsRsRsPtPPssAGLGsNsAPPIPDSRLGEE
Q8IWX8	T819	Sugiyama	CHERP DAN26 SCAF6	RSRSKSYSPGRRRRsRsRsPtPPssAGLGsNsAPPIPDSRL
Q8IX03	S542	EPSD\|PSP	WWC1 KIAA0869 KIBRA	RsLSGtPKSMTSLsPRSsLSsPSPPCsPLMADPLLAGDAFL
Q8IX03	S548	SIGNOR\|EPSD\|PSP	WWC1 KIAA0869 KIBRA	PKSMTSLsPRSsLSsPSPPCsPLMADPLLAGDAFLNSLEFE
Q8IZP0	S183	EPSD\|PSP	ABI1 SSH3BP1	NQPARTGTLSRtNPPtQKPPsPPMsGRGtLGRNtPyKtLEP
Q8IZP0	S216	EPSD\|PSP	ABI1 SSH3BP1	tPyKtLEPVKPPTVPNDyMtsPARLGsQHsPGRtAsLNQRP
Q8IZP0	S225	SIGNOR\|EPSD\|PSP	ABI1 SSH3BP1	KPPTVPNDyMtsPARLGsQHsPGRtAsLNQRPRTHsGSSGG
Q8IZP0	S267	EPSD\|PSP	ABI1 SSH3BP1	GSRENSGSSSIGIPIAVPtPsPPTIGPENISVPPPSGAPPA
Q8IZP0	S392	EPSD\|PSP	ABI1 SSH3BP1	LTPQIPLTGFVARVQENIADsPtPPPPPPPDDIPMFDDsPP
Q8IZP0	S410	EPSD\|PSP	ABI1 SSH3BP1	ADsPtPPPPPPPDDIPMFDDsPPPPPPPPVDyEDEEAAVVQ
Q8IZP0	T265	EPSD\|PSP	ABI1 SSH3BP1	GSGSRENSGSSSIGIPIAVPtPsPPTIGPENISVPPPSGAP
Q8IZP0	T394	EPSD\|PSP	ABI1 SSH3BP1	PQIPLTGFVARVQENIADsPtPPPPPPPDDIPMFDDsPPPP
Q8IZQ8	S815	GPS6	MYOCD MYCD	PFDPYATDSDEHLEVLLNSQsPLGKMSDVTLLKIGSEEPHF
Q8IZQ8	S862	GPS6	MYOCD MYCD	FSGKAAEDLFNAHEILPGPLsPMQTQFSPSSVDSNGLQLSF
Q8N122	S696	SIGNOR\|EPSD\|PSP	RPTOR KIAA1303 RAPTOR	SNFCTVALQFIEEEKNYALPsPATTEGGSLtPVRDsPCtPR
Q8N122	S8	SIGNOR\|EPSD\|PSP	RPTOR KIAA1303 RAPTOR	_____________MESEMLQsPLLGLGEEDEADLTDWNLPL
Q8N122	S863	SIGNOR\|EPSD\|PSP	RPTOR KIAA1303 RAPTOR	VNARPQRVLDtssLtQsAPAsPtNKGVHIHQAGGsPPAsst
Q8N1F7	S112	Sugiyama	NUP93 KIAA0095	PVKDTDIQGFLKNEKDNALLsAIEESRKRtFGMAEEYHRES
Q8N556	S265	Sugiyama	AFAP1 AFAP	KEAYSGCSGPVDSECPPPPssPVHKAELEKKLssERPssDG
Q8N9N5	T337	SIGNOR\|EPSD\|PSP	BANP BEND1 SMAR1	TAWRRKQRGQSLAVKSFSRRtPNSSSYCPSEPMMStPPPAS
Q8N9N5	T352	SIGNOR\|EPSD\|PSP	BANP BEND1 SMAR1	SFSRRtPNSSSYCPSEPMMStPPPASELPQPQPQPQALHYA
Q8NBJ5	S607	Sugiyama	COLGALT1 GLT25D1 PSEC0241	DRAKSQKMREQQALSREAKNsDVLQsPLDsAARDEL_____
Q8NBJ5	S612	Sugiyama	COLGALT1 GLT25D1 PSEC0241	QKMREQQALSREAKNsDVLQsPLDsAARDEL__________
Q8NBJ5	S616	Sugiyama	COLGALT1 GLT25D1 PSEC0241	EQQALSREAKNsDVLQsPLDsAARDEL______________
Q8NBJ7	S283	Sugiyama	SUMF2 PSEC0171 UNQ1968/PRO4500	GsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPPGEL__
Q8NBJ7	S44	Sugiyama	SUMF2 PSEC0171 UNQ1968/PRO4500	NGQATSMVQLQGGRFLMGtNsPDSRDGDGPVREATVKPFAI
Q8NDV7	S1047	Sugiyama	TNRC6A CAGH26 KIAA1460 TNRC6	PNGNSRSDQQAQVHQLLtPAsAISNKEASSGSGWGEPWGEP
Q8NDV7	T1044	Sugiyama	TNRC6A CAGH26 KIAA1460 TNRC6	KNVPNGNSRSDQQAQVHQLLtPAsAISNKEASSGSGWGEPW
Q8NET8	T264	SIGNOR\|EPSD\|PSP	TRPV3	HAKGAFFNPKYQHEGFYFGEtPLALAACTNQPEIVQLLMEH
Q8NFI4	S181	Sugiyama	ST13P5 FAM10A5	LQKPNAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA
Q8TB45	S235	SIGNOR\|PSP	DEPTOR DEPDC6	YQFRMNFRRRRRLMELLNEKsPssQEtHDsPFCLRKQSHDN
Q8TB72	S82	Sugiyama	PUM2 KIAA0235 PUMH2	MVQRRsGQGFHGNsEVNAILsPRsEsGGLGVsMVEYVLsss
Q8TC07	S675	Sugiyama	TBC1D15	TSAFQSNALPTLSASGARNDsPtQIPVssDVCRLtPA____
Q8WUI4	S109	Sugiyama	HDAC7 HDAC7A	LAEVILKKQQAALERtVHPNsPGIPYRTLEPLETEGATRSM
Q8WX93	S484	Sugiyama	PALLD KIAA0992 CGI-151	VRGAPPLQVQWFRQGsEIQDsPDFRILQKKPRSTAEPEEIC
Q8WX93	S688	EPSD\|PSP	PALLD KIAA0992 CGI-151	RLEQEAGARQPPPAPRsAPPsPPFPPPPAFPELAACtPPAs
Q8WX93	S808	EPSD\|PSP	PALLD KIAA0992 CGI-151	PEAPWGSSSPSPPPPPPPVFsPTAAFPVPDVFPLPPPPPPL
Q8WXI9	S122	Sugiyama	GATAD2B KIAA1150	DEPVDMSARRsEPERGRLtPsPDIIVLsDNEAssPRsSsRM
Q8WXI9	S135	Sugiyama	GATAD2B KIAA1150	ERGRLtPsPDIIVLsDNEAssPRsSsRMEERLKAANLEMFK
Q8WYP5	S1214	Sugiyama	AHCTF1 ELYS TMBS62 MSTP108	FSEFTPQSILRstLRstPLAsPsPsPGRsPQRLKEtRIsFV
Q8WYP5	S1222	Sugiyama	AHCTF1 ELYS TMBS62 MSTP108	ILRstLRstPLAsPsPsPGRsPQRLKEtRIsFVEEDVHPKW
Q92530	S153	Sugiyama	PSMF1	RIVSGIITPIHEQWEKANVssPHREFPPAtAREVDPLRIPP
Q92615	S664	Sugiyama	LARP4B KIAA0217 LARP5	ELRKPSYAEICQRTSKEPPssPLQPQKEQKPNTVGCGKEEK
Q92734	S183	Sugiyama	TFG	AsMsAFDPLKNQDEINKNVMsAFGLtDDQVsGPPsAPAEDR
Q92734	S197	Sugiyama	TFG	INKNVMsAFGLtDDQVsGPPsAPAEDRSGTPDSIASSSSAA
Q92793	S93	EPSD\|PSP	CREBBP CBP	LLRGGsGSSINPGIGNVsAssPVQQGLGGQAQGQPNSANMA
Q92797	T1257	EPSD\|PSP	SYMPK SPK	tLKEERsPQtLAPVGEDAMKtPsPAAEDAREPEAKGNs___
Q92804	S295	Sugiyama	TAF15 RBP56 TAF2N	TDKDTGKPKGEAtVsFDDPPsAKAAIDWFDGKEFHGNIIKV
Q92871	S242	Sugiyama	PMM1 PMMH22	PGGNDFEIFADPRTVGHSVVsPQDtVQRCREIFFPETAHEA
Q92879	S179	Sugiyama	CELF1 BRUNOL2 CUGBP CUGBP1 NAB50	AMAQTAIKAMHQAQtMEGCssPMVVKFADTQKDKEQKRMAQ
Q92908	S266	EPSD\|PSP	GATA6	AAGPGGAGSAAAHVSARFPYsPsPPMANGAAREPGGyAAAG
Q92922	T335	Sugiyama	SMARCC1 BAF155	DRKASANARKRKHsPsPPPPtPtEsRKKSGKKGQASLYGKR
Q92934	S75	EPSD\|PSP	BAD BBC6 BCL2L8	PTSSSHHGGAGAVEIRsRHssyPAGtEDDEGMGEEPsPFRG
Q92974	T679	SIGNOR\|EPSD\|PSP	ARHGEF2 KIAA0651 LFP40	IREVEGLKDLLVGPGVELLLtPREPALPLEPDsGGNtsPGV
Q93045	S62	SIGNOR\|ELM\|iPTMNet	STMN2 SCG10 SCGN10	VKQINKRAsGQAFELILKPPsPISEAPRTLAsPKKKDLsLE
Q93045	S73	SIGNOR\|ELM\|iPTMNet	STMN2 SCG10 SCGN10	AFELILKPPsPISEAPRTLAsPKKKDLsLEEIQKKLEAAEE
Q969H0	S176	PSP	FBXW7 FBW7 FBX30 SEL10	QLSSPFYTKTTKMKRKLDHGsEVRSFSLGKKPCKVSEYTST
Q969H0	T205	EPSD\|PSP	FBXW7 FBW7 FBX30 SEL10	KKPCKVSEYTSTTGLVPCSAtPTTFGDLRAANGQGQQRRRI
Q969R2	S762	PSP	OSBP2 KIAA1664 ORP4 OSBPL4	AHYVLSGSWDEQMECSKVMHssPssPsSDGKQKTVYQTLSA
Q969R2	S763	PSP	OSBP2 KIAA1664 ORP4 OSBPL4	HYVLSGSWDEQMECSKVMHssPssPsSDGKQKTVYQTLSAK
Q969R2	S766	PSP	OSBP2 KIAA1664 ORP4 OSBPL4	LSGSWDEQMECSKVMHssPssPsSDGKQKTVYQTLSAKLLW
Q969R2	S768	PSP	OSBP2 KIAA1664 ORP4 OSBPL4	GSWDEQMECSKVMHssPssPsSDGKQKTVYQTLSAKLLWKK
Q969V6	S454	SIGNOR\|EPSD\|PSP	MRTFA KIAA1438 MAL MKL1	ATVASSGVVKFGstGstPPVsPtPsERSLLSTGDENSTPGD
Q96B36	S212	Sugiyama	AKT1S1 PRAS40	GFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAED
Q96C19	S74	Sugiyama	EFHD2 SWS1	ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI
Q96D15	T72	Sugiyama	RCN3 UNQ239/PRO272	FQYDHEAFLGREVAKEFDQLtPEEsQARLGRIVDRMDRAGD
Q96EK9	S184	Sugiyama	KTI12 SBBI81	GSAQADVPKELEREEsGAAEsPALVtPDSEKSAKHGsGAFy
Q96EK9	T189	Sugiyama	KTI12 SBBI81	DVPKELEREEsGAAEsPALVtPDSEKSAKHGsGAFysPELL
Q96FF9	S209	SIGNOR\|EPSD\|PSP	CDCA5	TEVPRVCAKPWAPDMTLPGIsPPPEKQKRKKKKMPEILKTE
Q96FF9	S79	SIGNOR\|EPSD\|PSP	CDCA5	VLKRIVAHAVEVPAVQsPRRsPRIsFFLEKENEPPGRELTK
Q96IR7	S365	Sugiyama	HPDL GLOXD1	GATGFGQGNIRALWQsVQEQsARSQEA______________
Q96K76	S910	Sugiyama	USP47	DGDNGDssKstEtsDFENIEsPLNERDsSAsVDNRELEQHI
Q96MH2	S76	Sugiyama	HEXIM2 L3	EDLAGAVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPS
Q96MH2	S81	Sugiyama	HEXIM2 L3	AVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPSKRKRH
Q96Q27	S371	SIGNOR\|PSP	ASB2	RIVQMLLPVTSRTRIRRSGVsPLHLAAERNHDEVLEALLSA
Q96RK0	S1389	EPSD	CIC KIAA0306	TTDIDLKCKERVtDSESGDSsGEDPEGNKGFGRKVFSPVIR
Q96S38	S560	Sugiyama	RPS6KC1 RPK118	NGVDTKAIKSFPAHLAADsDsPSTQLRAHELKFFPNDDPEA
Q96S59	T163	Sugiyama	RANBP9 RANBPM	QEKELQRRLKRLYPAVDEQEtPLPRSWsPKDKFsYIGLsQN
Q96ST3	T161	Sugiyama	SIN3A	PQVYNDFLDIMKEFKSQsIDtPGVISRVSQLFKGHPDLIMG
Q99459	T385	Sugiyama	CDC5L KIAA0432 PCDC5RP	EAQNLMALtNVDtPLKGGLNtPLHEsDFsGVtPQRQVVQtP
Q99666	T1474	Sugiyama	RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6	DSFKKIFDEAKTAQEKDsLItPHVsRsstPREsPCGKIAVA
Q99714	T73	Sugiyama	HSD17B10 ERAB HADH2 MRPP2 SCHAD SDR5C1 XH98G2	KLGNNCVFAPADVtsEKDVQtALALAKGKFGRVDVAVNCAG
Q99733	S54	Sugiyama	NAP1L4 NAP2	NPRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQ
Q99733	T51	Sugiyama	NAP1L4 NAP2	VMQNPRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALK
Q99814	S484	SIGNOR\|PSP	EPAS1 BHLHE73 HIF2A MOP2 PASD2	APGSTTPSATSSSSSCSTPNsPEDYYTSLDNDLKIEVIEKL
Q99814	S672	PSP	EPAS1 BHLHE73 HIF2A MOP2 PASD2	WAVGDQRTEFLGAAPLGPPVsPPHVSTFKTRSAKGFGARGP
Q9BQE3	T73	Sugiyama	TUBA1C TUBA6	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3	T80	Sugiyama	TUBA1C TUBA6	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3	Y83	Sugiyama	TUBA1C TUBA6	PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BQG0	S11	Sugiyama	MYBBP1A P160	__________MEsRDPAQPMsPGEAtQsGARPADRYGLLKH
Q9BQG0	T1161	Sugiyama	MYBBP1A P160	TLGVQRPKLEKKDAKEIPsAtQsPIsKKRKKKGFLPETKKR
Q9BQQ3	S274	SIGNOR	GORASP1 GOLPH5 GRASP65	MEALLQAPGSSMEDPLPGPGsPSHSAPDPDGLPHFMETPLQ
Q9BR01	T11	SIGNOR\|EPSD\|PSP	SULT4A1 SULTX3	__________MAESEAEtPStPGEFESKYFEFHGVRLPPFC
Q9BTL3	S36	SIGNOR	RAMAC C15orf18 FAM103A1 RAMMET	ASRFTENDKEYQEYLKRPPEsPPIVEEWNSRAGGNQRNRGN
Q9BTU6	S51	Sugiyama	PI4K2A	VPGGAVRVAAAAGsGPsPPGsPGHDRERQPLLDRARGAAAQ
Q9BUB5	T250	SIGNOR	MKNK1 MNK1	ICDFDLGSGMKLNNSCTPITtPELTtPCGSAEYMAPEVVEV
Q9BUB5	T255	SIGNOR	MKNK1 MNK1	LGSGMKLNNSCTPITtPELTtPCGSAEYMAPEVVEVFTDQA
Q9BUB5	T385	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MKNK1 MNK1	AAQVLQHPWVQGQAPEKGLPtPQVLQRNSSTMDLTLFAAEA
Q9BXP5	S493	Sugiyama	SRRT ARS2 ASR2	VNIKEICWNLQNIRLRECELsPGVNRDLTRRVRNINGITQH
Q9BYG3	T238	Sugiyama	NIFK MKI67IP NOPP34	sGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELNDDDKD
Q9BYX7	T249	Sugiyama	POTEKP ACTBL3 FKSG30	MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BZI1	S317	SIGNOR	IRX2 IRXA2	sPPPEAAPRGGRKTPQGSRtsPGAPPPAsKPKLWSLAEIAT
Q9BZI1	S325	SIGNOR	IRX2 IRXA2	RGGRKTPQGSRtsPGAPPPAsKPKLWSLAEIATSDLKQPSL
Q9C0C2	S1029	Sugiyama	TNKS1BP1 KIAA1741 TAB182	LGEGsRDAGRPGERGsGGLFsPstAHVPDGALGQRDQssWQ
Q9C0C2	S1031	Sugiyama	TNKS1BP1 KIAA1741 TAB182	EGsRDAGRPGERGsGGLFsPstAHVPDGALGQRDQssWQNs
Q9C0C2	S1103	Sugiyama	TNKS1BP1 KIAA1741 TAB182	KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ
Q9C0C2	S1297	Sugiyama	TNKS1BP1 KIAA1741 TAB182	GQADWtPDLGLRNMAPGAVCsPGEsKELGVGQMDWGNNLGL
Q9C0C2	S435	Sugiyama	TNKS1BP1 KIAA1741 TAB182	DAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAALPQGQG
Q9C0C2	S601	Sugiyama	TNKS1BP1 KIAA1741 TAB182	LPLQQAEERyEsQEPLAGQEsPLPLATREAALPILEPVLGQ
Q9C0C2	S672	Sugiyama	TNKS1BP1 KIAA1741 TAB182	TLARAETtQARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsP
Q9C0C2	S712	Sugiyama	TNKS1BP1 KIAA1741 TAB182	PPPsGGGARRGAGAELKDtQsPstCsEGLLGWsQKDLQSEF
Q9C0C2	T715	Sugiyama	TNKS1BP1 KIAA1741 TAB182	sGGGARRGAGAELKDtQsPstCsEGLLGWsQKDLQSEFGIT
Q9H0B6	S445	Sugiyama	KLC2	RRDsAPyGEyGsWYKACKVDsPtVNTTLRSLGALYRRQGKL
Q9H0F6	S146	PSP	SHARPIN SIPL1 PSEC0216	GSKsNsPPALGPEACPVsLPsPPEASTLKGPPPEADLPRsP
Q9H0F6	S165	PSP	SHARPIN SIPL1 PSEC0216	PsPPEASTLKGPPPEADLPRsPGNLtEREELAGSLARAIAG
Q9H0F6	T309	PSP	SHARPIN SIPL1 PSEC0216	RQDGDPAFLYLLSAPREAPAtGPsPQHPQKMDGELGRLFPP
Q9H2U2	S317	Sugiyama	PPA2 HSPC124	DSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK___
Q9H3K6	T76	Sugiyama	BOLA2 BOLA2A My016; BOLA2B	VNACLAEELPHIHAFEQKTLtPDQWARERQK__________
Q9H488	S264	Sugiyama	POFUT1 FUT12 KIAA0180	DWKNACAMLKDGTAGSHFMAsPQCVGySRSTAAPLTMTMCL
Q9H4A3	S1261	Sugiyama	WNK1 HSN2 KDP KIAA0344 PRKWNK1	GIPTSSLTQVVHSAGRRFIVsPVPEsRLRESKVFPSEITDT
Q9H4A3	S2027	Sugiyama	WNK1 HSN2 KDP KIAA0344 PRKWNK1	LNGPssDPEAAFLSRDVDDGsGsPHsPHQLssKSLPSQNLS
Q9H4A3	S2032	Sugiyama	WNK1 HSN2 KDP KIAA0344 PRKWNK1	sDPEAAFLSRDVDDGsGsPHsPHQLssKSLPSQNLSQSLSN
Q9H501	S198	Sugiyama	ESF1 ABTAP C20orf6 HDCMC28P	DssLEEKQRTLDsGtSEIVKsPRIECSKTRREMQSVVQLIM
Q9H773	S26	Sugiyama	DCTPP1 XTP3TPA CDA03	GEIRGDTGGEDTAAPGRFsFsPEPTLEDIRRLHAEFAAERD
Q9H773	S85	Sugiyama	DCTPP1 XTP3TPA CDA03	GELAELFQWKTDGEPGPQGWsPRERAALQEELSDVLIYLVA
Q9H8Y8	T222	EPSD\|PSP	GORASP2 GOLPH6	IPTRPFEEGKKIsLPGQMAGtPItPLKDGFTEVQLSSVNPP
Q9H8Y8	T225	EPSD\|PSP	GORASP2 GOLPH6	RPFEEGKKIsLPGQMAGtPItPLKDGFTEVQLSSVNPPSLS
Q9H9Z2	S200	SIGNOR\|PSP	LIN28A CSDD1 LIN28 ZCCHC1	QGPSAQGKPTYFREEEEEIHsPtLLPEAQN___________
Q9HAV4	S416	SIGNOR	XPO5 KIAA1291 RANBP21	KYLRASMTNLVKMGFPSKTDsPSCEYSRFDFDSDEDFNAFF
Q9HAV4	S497	SIGNOR	XPO5 KIAA1291 RANBP21	GSVNSCSAVGTGEGSLCSVFsPSFVQWEAMTLFLESVITQM
Q9HAV4	T345	SIGNOR	XPO5 KIAA1291 RANBP21	VLCALGNQLCALLGADSDVEtPSNFGKYLESFLAFTTHPSQ
Q9HCE7	T223	PSP	SMURF1 KIAA1625	QDQRLQAQRLRNPDVRGSLQtPQNRPHGHQsPELPEGYEQR
Q9NQ39	S157	Sugiyama	RPS10P5 RPS10L	TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ66	S982	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	PLCB1 KIAA0581	RRAALEKSAKKDSKKKsEPssPDHGsstIEQDLAALDAEMT
Q9NQX3	S268	SIGNOR	GPHN GPH KIAA1385	IISRGVQVLPRDTAsLsttPsEsPRAQAtsRLstAsCPtPK
Q9NR45	S253	Sugiyama	NANS SAS	KVLERHITLDKTWKGsDHsAsLEPGELAELVRSVRLVERAL
Q9NRA0	S387	SIGNOR\|EPSD\|PSP	SPHK2 SK2	ATLHTYRGRLsyLPAtVEPAsPtPAHsLPRAKsELtLtPDP
Q9NRA0	T614	SIGNOR\|EPSD\|PSP	SPHK2 SK2	SLGCPQLGYAAARAFRLEPLtPRGVLTVDGEQVEYGPLQAQ
Q9NRF2	S96	GPS6\|EPSD\|PSP	SH2B1 KIAA1299 SH2B	FEAEVARAsGsLsPPILAPLsPGAEIsPHDLSLESCRVGGP
Q9NTJ3	S22	Sugiyama	SMC4 CAPC SMC4L1	PRKGTQPSTARRREEGPPPPsPDGAssDAEPEPPsGRtEsP
Q9NTJ3	S28	Sugiyama	SMC4 CAPC SMC4L1	PSTARRREEGPPPPsPDGAssDAEPEPPsGRtEsPAtAAEt
Q9NUQ3	S97	Sugiyama	TXLNG CXorf15 ELRG LSR5	KHSLEEDEGsDFItENRNLVsPAyCtQEsREEIPGGEARTD
Q9NUU7	S85	Sugiyama	DDX19A DDX19L	IRSNLVDNtNQVEVLQRDPNsPLysVKsFEELRLKPQLLQG
Q9NWS0	T195	Sugiyama	PIH1D1 NOP17	sQQNIRSEQRPRIQELGDLytPAPGRAESGPEKPHLNLWLE
Q9NYA1	S225	SIGNOR\|EPSD\|PSP	SPHK1 SK1 SPHK SPK	TYRGRLAYLPVGRVGSKTPAsPVVVQQGPVDAHLVPLEEPV
Q9NYB0	S203	Sugiyama	TERF2IP DRIP5 RAP1 PP8000	RYLKHLRGQEHKyLLGDAPVsPssQKLKRKAEEDPEAADsG
Q9NYD6	S189	Sugiyama	HOXC10 HOX3I	DFEAPFEQRASLNPRAEHLEsPQLGGKVSFPEtPKsDsQtP
Q9NYV6	S633	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	RRN3 TIFIA	VPQNDTVIGItPSsFDtHFRsPsssVGsPPVLyMQPsPL__
Q9NYV6	S649	SIGNOR	RRN3 TIFIA	tHFRsPsssVGsPPVLyMQPsPL__________________
Q9NZB2	T991	Sugiyama	FAM120A C9orf10 KIAA0183 OSSA	PLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKNQ
Q9NZI5	S76	PSP	GRHL1 LBP32 MGR TFCP2L2	DSAAALGLLYDYYKVPRERRsstAKPEVEHPEPDHSKRNsI
Q9NZQ3	T242	PSP	NCKIPSD AF3P21 SPIN90	SLDTLyTSSSPSEPGSSCSPtPPPVPRRGtHTTVsQVQPPP
Q9NZT2	S378	Sugiyama	OGFR	LERsQGDEAGGHGEDRPEPLsPKEsKKRKLELSRREQPPTE
Q9NZV1	S184	Sugiyama	CRIM1 S52 UNQ1886/PRO4330	LKRIEEEKPDCSKARCEVQFsPRCPEDSVLIEGYAPPGECC
Q9UBN7	S1035	SIGNOR\|EPSD\|PSP	HDAC6 KIAA0901 JM21	GTELIQTPLASSTDHQtPPTsPVQGTTPQISPSTLIGSLRT
Q9UBN7	T1031	SIGNOR\|EPSD\|PSP	HDAC6 KIAA0901 JM21	EAPGGTELIQTPLASSTDHQtPPTsPVQGTTPQISPSTLIG
Q9UBS5	S868	SIGNOR	GABBR1 GPRC3A	TLVVLFVPKMRRLITRGEWQsEAQDtMKTGSstNNNEEEKS
Q9UBS5	T873	SIGNOR	GABBR1 GPRC3A	FVPKMRRLITRGEWQsEAQDtMKTGSstNNNEEEKSRLLEK
Q9UGV2	S361	Sugiyama	NDRG3	sPFsRsVtsNQsDGtQESCEsPDVLDRHQTMEVsC______
Q9UHB6	S362	SIGNOR\|EPSD\|PSP	LIMA1 EPLIN SREBP3 PP624	DsRDsQVKSEVQQPVHPKPLsPDsRAssLsEssPPKAMKKF
Q9UHB6	S374	EPSD\|PSP	LIMA1 EPLIN SREBP3 PP624	QPVHPKPLsPDsRAssLsEssPPKAMKKFQAPARETCVECQ
Q9UHB6	S490	Sugiyama	LIMA1 EPLIN SREBP3 PP624	ENEEILERPAQLANAREtPHsPGVEDAPIAKVGVLAAsMEA
Q9UHB6	S604	SIGNOR\|EPSD\|PSP	LIMA1 EPLIN SREBP3 PP624	LKERSRPFTVAASFQstsVKsPKtVsPPIRKGWsMsEQSEE
Q9UHL4	S213	Sugiyama	DPP7 DPP2 QPP	AGLGDSNQFFRDVTADFEGQsPKCTQGVREAFRQIKDLFLQ
Q9UI10	T86	Sugiyama	EIF2B4 EIF2BD	AAQCQVGPTRELPESGIQLGtPREKVPAGRSKAELRAERRA
Q9UI15	T190	Sugiyama	TAGLN3 NP25	GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UIG0	S158	SIGNOR\|EPSD\|PSP	BAZ1B WBSC10 WBSCR10 WBSCR9 WSTF	HPLEKVDEEATEKKsDGACDsPssDKENssQIAQDHQKKET
Q9UJY1	S24	EPSD\|PSP	HSPB8 CRYAC E2IG1 HSP22 PP1629	GQMPFSCHYPsRLRRDPFRDsPLsSRLLDDGFGMDPFPDDL
Q9UJY1	S27	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	HSPB8 CRYAC E2IG1 HSP22 PP1629	PFSCHYPsRLRRDPFRDsPLsSRLLDDGFGMDPFPDDLTAS
Q9UJY1	T87	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	HSPB8 CRYAC E2IG1 HSP22 PP1629	GMVPRGPTATARFGVPAEGRtPPPFPGEPWKVCVNVHSFKP
Q9UKX7	S221	SIGNOR\|EPSD\|PSP\|Sugiyama	NUP50 NPAP60L PRO1146	HGNsGRNsESEsNKVAAEtQsPsLFGstKLQQEStFLFHGN
Q9UKX7	S315	SIGNOR\|EPSD\|PSP	NUP50 NPAP60L PRO1146	FsPGNSSLFGKDttQsKPVssPFPtKPLEGQAEGDsGECKG
Q9ULC4	T81	GPS6\|EPSD\|PSP	MCTS1 MCT1	ILTVNGELLFFRQREGPFYPtLRLLHKYPFILPHQQVDKGA
Q9ULD2	S1264	Sugiyama	MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1	RsPtssAIPLQsPRNsGsFPsPsIsPR______________
Q9ULD2	S1268	Sugiyama	MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1	ssAIPLQsPRNsGsFPsPsIsPR__________________
Q9ULV5	S298	PSP	HSF4	SPSSDGRREKGLALLKEEPAsPGGDGEAGLALAPNECDFCV
Q9UMR2	S86	Sugiyama	DDX19B DBP5 DDX19 TDBP	IRSNLVDNtNQVEVLQRDPNsPLysVKsFEELRLKPQLLQG
Q9UNA1	S685	SIGNOR	ARHGAP26 GRAF KIAA0621 OPHN1L	PNPSPTSPLSPSWPMFSAPSsPMPTSSTSSDSSPVRSVAGF
Q9UNX3	T8	Sugiyama	RPL26L1 RPL26P1	_____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UPT5	S250	EPSD\|PSP	EXOC7 EXO70 KIAA1067	SIKGLKEHFHKsssssGVPysPAIPNKRKDTPTKKPVKRPG
Q9UQ13	T507	SIGNOR\|PSP	SHOC2 KIAA0862	PRGIGHLTNLTHLGLGENLLtHLPEEIGTLENLEELYLNDN
Q9UQ35	S1320	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	sMASSWGGPHFsPEHKELsNsPLRENsFGsPLEFRNsGPLG
Q9UQ35	S1329	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	HFsPEHKELsNsPLRENsFGsPLEFRNsGPLGTEMNtGFss
Q9UQ35	S2132	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	SRMsCFsRPsMsPtPLDRCRsPGMLEPLGssRtPMsVLQQA
Q9UQ35	S2272	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	tAVNLADsRtPAAAAAMNLAsPRtAVAPsAVNLADPRtPtA
Q9UQC2	S623	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	GAB2 KIAA0571	PAPKKSTGSVDyLALDFQPssPsPHRKPSTssVtSDEKVDy
Q9Y266	S136	Sugiyama	NUDC	QLEIDQKKDAENHEAQLKNGsLDsPGKQDtEEDEEEDEKDK
Q9Y266	S139	Sugiyama	NUDC	IDQKKDAENHEAQLKNGsLDsPGKQDtEEDEEEDEKDKGKL
Q9Y266	S304	Sugiyama	NUDC	RsMVEKMMYDQRQKsMGLPtsDEQKKQEILKKFMDQHPEMD
Q9Y266	T303	Sugiyama	NUDC	tRsMVEKMMYDQRQKsMGLPtsDEQKKQEILKKFMDQHPEM
Q9Y2R5	S128	Sugiyama	MRPS17 RPMS17 HSPC011	SPLSSETTQLSKNLEELNIssAQ__________________
Q9Y2V2	S41	Sugiyama	CARHSP1	LDtPRsRERsPsPLRGNVVPsPLPtRRtRtFsAtVRASQGP
Q9Y2W2	S237	Sugiyama	WBP11 NPWBP SIPP1 SNP70	RKVGFALDLPPRRRDEDMLysPELAQRGHDDDVSSTSEDDG
Q9Y3F4	S228	Sugiyama	STRAP MAWD UNRIP	FHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLy
Q9Y3F4	T117	Sugiyama	STRAP MAWD UNRIP	LAHKHIVKtVDFtQDSNyLLtGGQDKLLRIYDLNKPEAEPK
Q9Y3F4	T225	Sugiyama	STRAP MAWD UNRIP	SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF
Q9Y3R0	S734	SIGNOR	GRIP1	IHIGDRILAINSSSLKGKPLsEAIHLLQMAGETVTLKIKKQ
Q9Y4E8	S229	Sugiyama	USP15 KIAA0529	LVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPssLsNN
Q9Y4E8	T226	Sugiyama	USP15 KIAA0529	GQVLVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPssL
Q9Y5A9	S39	PSP	YTHDF2 HGRG8	QNGSVHQKDGLNDDDFEPyLsPQARPNNAYTAMSDSYLPSY
Q9Y5A9	T381	PSP	YTHDF2 HGRG8	FGHNGVDGNGVGQSQAGSGStPSEPHPVLEKLRsINNYNPK
Q9Y5U2	S146	Sugiyama	TSSC4	LAPsGRsPVEGLGRAHRsPAsPRVPPVPDYVAHPERWTKYS
Q9Y613	S498	PSP	FHOD1 FHOS FHOS1	PDARQLWDsPEtAPAARtPQsPAPCVLLRAQRsLAPEPKEP
Q9Y6G9	S207	Sugiyama	DYNC1LI1 DNCLI1	EQKLIRDFQEyVEPGEDFPAsPQRRNtAsQEDKDDsVVLPL
Q9Y6G9	S516	Sugiyama	DYNC1LI1 DNCLI1	HAELDRITRKPVtVsPttPtsPtEGEAs_____________
Q9Y6G9	T515	Sugiyama	DYNC1LI1 DNCLI1	VHAELDRITRKPVtVsPttPtsPtEGEAs____________
Q9Y6W5	S343	EPSD\|PSP	WASF2 WAVE2	PPPPPPMIGIPPPPPPVGFGsPGtPPPPsPPSFPPHPDFAA
Q9Y6W5	S351	EPSD\|PSP	WASF2 WAVE2	GIPPPPPPVGFGsPGtPPPPsPPSFPPHPDFAAPPPPPPPP
Q9Y6W5	T346	EPSD\|PSP	WASF2 WAVE2	PPPMIGIPPPPPPVGFGsPGtPPPPsPPSFPPHPDFAAPPP

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

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name	reactome_id	p	-log10p	ref_path	ref_path_lowest
Chromatin organization	R-HSA-4839726	6.894622e-08	7.161	0	0
Chromatin modifying enzymes	R-HSA-3247509	6.834638e-07	6.165	0	0
Diseases of signal transduction by growth factor receptors and second messengers	R-HSA-5663202	3.520733e-06	5.453	1	0
Cell Cycle	R-HSA-1640170	1.382897e-05	4.859	0	0
NRAGE signals death through JNK	R-HSA-193648	2.395256e-05	4.621	0	0
Cell Cycle, Mitotic	R-HSA-69278	3.936098e-05	4.405	0	0
Formation of WDR5-containing histone-modifying complexes	R-HSA-9772755	6.540216e-05	4.184	0	0
Binding of TCF/LEF:CTNNB1 to target gene promoters	R-HSA-4411364	6.944622e-05	4.158	0	0
Transport of the SLBP Dependant Mature mRNA	R-HSA-159230	1.206816e-04	3.918	0	0
RUNX3 regulates BCL2L11 (BIM) transcription	R-HSA-8952158	1.713810e-04	3.766	0	0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	R-HSA-141444	2.046703e-04	3.689	0	0
Amplification of signal from the kinetochores	R-HSA-141424	2.046703e-04	3.689	0	0
Estrogen-dependent gene expression	R-HSA-9018519	2.302035e-04	3.638	0	0
Formation of the embryonic stem cell BAF (esBAF) complex	R-HSA-9933946	2.752521e-04	3.560	0	0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	R-HSA-8939243	2.915091e-04	3.535	0	0
Transport of the SLBP independent Mature mRNA	R-HSA-159227	2.915091e-04	3.535	0	0
Transport of Mature mRNAs Derived from Intronless Transcripts	R-HSA-159234	2.418757e-04	3.616	0	0
Cell death signalling via NRAGE, NRIF and NADE	R-HSA-204998	2.894643e-04	3.538	0	0
ATP-dependent chromatin remodelers	R-HSA-9932444	3.245418e-04	3.489	0	0
SWI/SNF chromatin remodelers	R-HSA-9932451	3.245418e-04	3.489	0	0
Epigenetic regulation of gene expression	R-HSA-212165	3.147931e-04	3.502	0	0
Signaling by ALK fusions and activated point mutants	R-HSA-9725370	3.827712e-04	3.417	1	0
Signaling by ALK in cancer	R-HSA-9700206	3.827712e-04	3.417	1	0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	R-HSA-5619107	4.102681e-04	3.387	0	0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	R-HSA-9931510	4.354888e-04	3.361	0	0
HATs acetylate histones	R-HSA-3214847	4.811625e-04	3.318	0	0
p75 NTR receptor-mediated signalling	R-HSA-193704	4.811625e-04	3.318	0	0
Nuclear import of Rev protein	R-HSA-180746	4.858148e-04	3.314	0	0
IP3 and IP4 transport between cytosol and nucleus	R-HSA-1855196	5.344614e-04	3.272	0	0
IP6 and IP7 transport between cytosol and nucleus	R-HSA-1855229	5.344614e-04	3.272	0	0
Transport of Mature mRNA Derived from an Intronless Transcript	R-HSA-159231	5.488759e-04	3.261	0	0
Nuclear Envelope Breakdown	R-HSA-2980766	5.630287e-04	3.249	0	0
Transcription of E2F targets under negative control by DREAM complex	R-HSA-1362277	6.165042e-04	3.210	0	0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	R-HSA-9934037	6.165042e-04	3.210	0	0
Nuclear Pore Complex (NPC) Disassembly	R-HSA-3301854	6.187714e-04	3.208	0	0
IPs transport between nucleus and cytosol	R-HSA-1855170	8.803504e-04	3.055	0	0
Vpr-mediated nuclear import of PICs	R-HSA-180910	9.791894e-04	3.009	0	0
TGFBR3 expression	R-HSA-9839394	1.068394e-03	2.971	0	0
Death Receptor Signaling	R-HSA-73887	1.045112e-03	2.981	0	0
Regulation of TP53 Activity	R-HSA-5633007	1.069306e-03	2.971	0	0
Mitotic Spindle Checkpoint	R-HSA-69618	1.137585e-03	2.944	0	0
Regulation of Glucokinase by Glucokinase Regulatory Protein	R-HSA-170822	1.114274e-03	2.953	0	0
Transport of Mature Transcript to Cytoplasm	R-HSA-72202	1.208392e-03	2.918	0	0
Transcriptional regulation of granulopoiesis	R-HSA-9616222	1.352748e-03	2.869	0	0
Repression of WNT target genes	R-HSA-4641265	1.503642e-03	2.823	0	0
Expression of BMAL (ARNTL), CLOCK, and NPAS2	R-HSA-9931509	1.502821e-03	2.823	0	0
Signal Transduction	R-HSA-162582	1.560432e-03	2.807	1	0
Interactions of Vpr with host cellular proteins	R-HSA-176033	1.842076e-03	2.735	0	0
Interactions of Rev with host cellular proteins	R-HSA-177243	1.842076e-03	2.735	0	0
G0 and Early G1	R-HSA-1538133	2.000106e-03	2.699	0	0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex	R-HSA-9931521	2.219981e-03	2.654	0	0
Regulation of PTEN gene transcription	R-HSA-8943724	2.239470e-03	2.650	1	1
RUNX3 regulates WNT signaling	R-HSA-8951430	2.363163e-03	2.627	0	0
Mitotic Prophase	R-HSA-68875	2.394880e-03	2.621	0	0
ChREBP activates metabolic gene expression	R-HSA-163765	2.908039e-03	2.536	0	0
Formation of the polybromo-BAF (pBAF) complex	R-HSA-9933939	3.075874e-03	2.512	0	0
G alpha (12/13) signalling events	R-HSA-416482	3.071884e-03	2.513	0	0
Heme signaling	R-HSA-9707616	3.053712e-03	2.515	0	0
TP53 Regulates Transcription of Cell Cycle Genes	R-HSA-6791312	3.150856e-03	2.502	0	0
Rev-mediated nuclear export of HIV RNA	R-HSA-165054	3.205380e-03	2.494	0	0
Transport of Mature mRNA derived from an Intron-Containing Transcript	R-HSA-159236	3.236693e-03	2.490	0	0
Signaling by NTRK1 (TRKA)	R-HSA-187037	3.364742e-03	2.473	1	0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	R-HSA-9933387	3.576347e-03	2.447	0	0
Interleukin-37 signaling	R-HSA-9008059	3.576347e-03	2.447	0	0
Nuclear events stimulated by ALK signaling in cancer	R-HSA-9725371	3.866797e-03	2.413	1	1
EML4 and NUDC in mitotic spindle formation	R-HSA-9648025	3.743909e-03	2.427	0	0
NS1 Mediated Effects on Host Pathways	R-HSA-168276	3.874537e-03	2.412	0	0
Cell-extracellular matrix interactions	R-HSA-446353	4.234186e-03	2.373	0	0
Regulation of MITF-M dependent genes involved in metabolism	R-HSA-9854907	4.639270e-03	2.334	0	0
RUNX3 regulates CDKN1A transcription	R-HSA-8941855	4.529575e-03	2.344	0	0
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	4.845444e-03	2.315	0	0
Epigenetic regulation by WDR5-containing histone modifying complexes	R-HSA-9917777	5.541969e-03	2.256	0	0
Regulation of MITF-M-dependent genes involved in pigmentation	R-HSA-9824585	5.480010e-03	2.261	0	0
Circadian clock	R-HSA-9909396	5.473030e-03	2.262	0	0
Signaling by TGFB family members	R-HSA-9006936	5.529687e-03	2.257	1	0
RUNX2 regulates bone development	R-HSA-8941326	5.542141e-03	2.256	1	0
PKMTs methylate histone lysines	R-HSA-3214841	5.553430e-03	2.255	0	0
G1/S-Specific Transcription	R-HSA-69205	5.542141e-03	2.256	0	0
Transport of Ribonucleoproteins into the Host Nucleus	R-HSA-168271	5.553430e-03	2.255	0	0
Signaling by TGF-beta Receptor Complex	R-HSA-170834	5.873622e-03	2.231	1	0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex	R-HSA-9931530	5.928085e-03	2.227	0	0
Transcriptional Regulation by TP53	R-HSA-3700989	6.138728e-03	2.212	0	0
Gene expression (Transcription)	R-HSA-74160	6.222615e-03	2.206	1	0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	R-HSA-2173796	6.646521e-03	2.177	1	1
Deactivation of the beta-catenin transactivating complex	R-HSA-3769402	6.646521e-03	2.177	0	0
Mitotic Prometaphase	R-HSA-68877	7.254339e-03	2.139	0	0
M Phase	R-HSA-68886	6.979679e-03	2.156	0	0
Regulation of NFE2L2 gene expression	R-HSA-9818749	7.339277e-03	2.134	0	0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	R-HSA-6804114	7.528569e-03	2.123	0	0
Signaling by PTK6	R-HSA-8848021	7.532761e-03	2.123	0	0
Signaling by Non-Receptor Tyrosine Kinases	R-HSA-9006927	7.532761e-03	2.123	0	0
Regulation of TP53 Activity through Association with Co-factors	R-HSA-6804759	8.111192e-03	2.091	0	0
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	R-HSA-2559584	8.111192e-03	2.091	0	0
Formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	7.969372e-03	2.099	0	0
GRB7 events in ERBB2 signaling	R-HSA-1306955	8.683161e-03	2.061	0	0
Cell Cycle Checkpoints	R-HSA-69620	8.958221e-03	2.048	0	0
Signaling by NTRKs	R-HSA-166520	9.268411e-03	2.033	1	0
NOTCH3 Intracellular Domain Regulates Transcription	R-HSA-9013508	9.473731e-03	2.023	0	0
NOTCH1 Intracellular Domain Regulates Transcription	R-HSA-2122947	1.017771e-02	1.992	0	0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	R-HSA-8864260	1.064273e-02	1.973	0	0
Transcriptional regulation by RUNX3	R-HSA-8878159	1.080934e-02	1.966	0	0
Formation of the canonical BAF (cBAF) complex	R-HSA-9933937	1.083533e-02	1.965	0	0
ERBB2 Activates PTK6 Signaling	R-HSA-8847993	1.083533e-02	1.965	0	0
Nuclear signaling by ERBB4	R-HSA-1251985	1.103370e-02	1.957	0	0
Activation of PUMA and translocation to mitochondria	R-HSA-139915	1.118027e-02	1.952	0	0
NEP/NS2 Interacts with the Cellular Export Machinery	R-HSA-168333	1.235862e-02	1.908	0	0
Polo-like kinase mediated events	R-HSA-156711	1.245739e-02	1.905	0	0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	R-HSA-2173793	1.268525e-02	1.897	1	0
ERBB2 Regulates Cell Motility	R-HSA-6785631	1.416870e-02	1.849	0	0
Notch-HLH transcription pathway	R-HSA-350054	1.333000e-02	1.875	0	0
RET signaling	R-HSA-8853659	1.335786e-02	1.874	0	0
Signaling by TGFBR3	R-HSA-9839373	1.428178e-02	1.845	0	0
tRNA processing in the nucleus	R-HSA-6784531	1.347896e-02	1.870	0	0
Export of Viral Ribonucleoproteins from Nucleus	R-HSA-168274	1.428178e-02	1.845	0	0
Adipogenesis	R-HSA-9843745	1.442156e-02	1.841	0	0
Activation of RAC1	R-HSA-428540	1.562187e-02	1.806	0	0
Regulation of TP53 Activity through Acetylation	R-HSA-6804758	1.617974e-02	1.791	0	0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	R-HSA-111453	1.620351e-02	1.790	0	0
RUNX3 regulates RUNX1-mediated transcription	R-HSA-8951911	1.647090e-02	1.783	0	0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	R-HSA-1362300	1.817668e-02	1.740	0	0
Metabolism of non-coding RNA	R-HSA-194441	1.853462e-02	1.732	0	0
snRNP Assembly	R-HSA-191859	1.853462e-02	1.732	0	0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	R-HSA-6804116	1.817668e-02	1.740	0	0
Signaling by NOTCH1	R-HSA-1980143	1.828340e-02	1.738	0	0
NGF-stimulated transcription	R-HSA-9031628	1.881097e-02	1.726	0	0
Signaling by ALK	R-HSA-201556	2.121707e-02	1.673	0	0
Regulation of PD-L1(CD274) transcription	R-HSA-9909649	2.160365e-02	1.665	0	0
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	2.214841e-02	1.655	1	0
GRB2 events in ERBB2 signaling	R-HSA-1963640	2.292040e-02	1.640	0	0
Signaling by ERBB2 in Cancer	R-HSA-1227990	2.319524e-02	1.635	0	0
TP53 Regulates Transcription of DNA Repair Genes	R-HSA-6796648	2.254313e-02	1.647	0	0
Cellular response to heat stress	R-HSA-3371556	2.419306e-02	1.616	1	0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	R-HSA-9844594	2.447605e-02	1.611	0	0
Transcriptional regulation of brown and beige adipocyte differentiation	R-HSA-9843743	2.447605e-02	1.611	0	0
Late Phase of HIV Life Cycle	R-HSA-162599	2.441466e-02	1.612	0	0
Viral Messenger RNA Synthesis	R-HSA-168325	2.345431e-02	1.630	0	0
Cellular Senescence	R-HSA-2559583	2.606749e-02	1.584	1	0
NFE2L2 regulating tumorigenic genes	R-HSA-9818030	2.669385e-02	1.574	0	0
Formation of the non-canonical BAF (ncBAF) complex	R-HSA-9933947	2.669385e-02	1.574	0	0
Inositol phosphate metabolism	R-HSA-1483249	2.687971e-02	1.571	0	0
Diseases of Telomere Maintenance	R-HSA-9673013	2.913141e-02	1.536	0	0
Defective Inhibition of DNA Recombination at Telomere	R-HSA-9670621	2.913141e-02	1.536	0	0
Alternative Lengthening of Telomeres (ALT)	R-HSA-9006821	2.913141e-02	1.536	0	0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations	R-HSA-9670615	2.913141e-02	1.536	0	0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	R-HSA-9670613	2.913141e-02	1.536	0	0
PI3K events in ERBB2 signaling	R-HSA-1963642	2.845533e-02	1.546	0	0
MITF-M-dependent gene expression	R-HSA-9856651	2.753658e-02	1.560	0	0
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	3.007833e-02	1.522	0	0
HIV Life Cycle	R-HSA-162587	2.879792e-02	1.541	0	0
ISG15 antiviral mechanism	R-HSA-1169408	3.013893e-02	1.521	1	1
Positive Regulation of CDH1 Gene Transcription	R-HSA-9764790	3.029081e-02	1.519	0	0
Regulation of TP53 Activity through Phosphorylation	R-HSA-6804756	3.033432e-02	1.518	0	0
Regulation of CDH1 Gene Transcription	R-HSA-9764560	3.300883e-02	1.481	1	0
Downregulation of TGF-beta receptor signaling	R-HSA-2173788	3.447267e-02	1.463	0	0
FOXO-mediated transcription of cell death genes	R-HSA-9614657	3.483016e-02	1.458	0	0
Signaling by cytosolic FGFR1 fusion mutants	R-HSA-1839117	3.483016e-02	1.458	0	0
Ephrin signaling	R-HSA-3928664	3.483016e-02	1.458	0	0
Cardiogenesis	R-HSA-9733709	3.678157e-02	1.434	0	0
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	4.075480e-02	1.390	0	0
Transcriptional regulation by RUNX1	R-HSA-8878171	4.122225e-02	1.385	0	0
RUNX2 regulates osteoblast differentiation	R-HSA-8940973	3.899492e-02	1.409	1	1
Signaling by NOTCH1 PEST Domain Mutants in Cancer	R-HSA-2644602	3.960790e-02	1.402	0	0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	R-HSA-2894862	3.960790e-02	1.402	0	0
Constitutive Signaling by NOTCH1 PEST Domain Mutants	R-HSA-2644606	3.960790e-02	1.402	0	0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	R-HSA-2894858	3.960790e-02	1.402	0	0
Signaling by NOTCH1 in Cancer	R-HSA-2644603	3.960790e-02	1.402	0	0
STAT3 nuclear events downstream of ALK signaling	R-HSA-9701898	4.201580e-02	1.377	0	0
Telomere C-strand synthesis initiation	R-HSA-174430	4.201580e-02	1.377	0	0
DCC mediated attractive signaling	R-HSA-418885	4.201580e-02	1.377	0	0
Impaired BRCA2 binding to PALB2	R-HSA-9709603	4.208581e-02	1.376	0	0
EGR2 and SOX10-mediated initiation of Schwann cell myelination	R-HSA-9619665	4.233006e-02	1.373	0	0
Oncogenic MAPK signaling	R-HSA-6802957	4.355093e-02	1.361	1	0
Regulation of HMOX1 expression and activity	R-HSA-9707587	4.595157e-02	1.338	0	0
NFE2L2 regulating ER-stress associated genes	R-HSA-9818035	4.595157e-02	1.338	0	0
Role of ABL in ROBO-SLIT signaling	R-HSA-428890	4.470901e-02	1.350	0	0
SHOC2 M1731 mutant abolishes MRAS complex function	R-HSA-9726840	4.470901e-02	1.350	0	0
VxPx cargo-targeting to cilium	R-HSA-5620916	5.025473e-02	1.299	0	0
Defective homologous recombination repair (HRR) due to PALB2 loss of function	R-HSA-9701193	5.025473e-02	1.299	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	R-HSA-9704331	5.025473e-02	1.299	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	R-HSA-9704646	5.025473e-02	1.299	0	0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	R-HSA-9701192	5.025473e-02	1.299	0	0
Signaling by ERBB2 TMD/JMD mutants	R-HSA-9665686	4.802497e-02	1.319	0	0
Deadenylation of mRNA	R-HSA-429947	4.802497e-02	1.319	0	0
Signaling by ERBB2 KD Mutants	R-HSA-9664565	4.527936e-02	1.344	0	0
Impaired BRCA2 binding to RAD51	R-HSA-9709570	4.527936e-02	1.344	0	0
Signaling by EGFR	R-HSA-177929	4.819011e-02	1.317	0	0
Formation of definitive endoderm	R-HSA-9823730	5.025473e-02	1.299	0	0
Mitotic Anaphase	R-HSA-68882	4.880028e-02	1.312	0	0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters	R-HSA-9931512	5.032392e-02	1.298	0	0
Mitotic Metaphase and Anaphase	R-HSA-2555396	5.137188e-02	1.289	0	0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)	R-HSA-9942503	5.139327e-02	1.289	0	0
Differentiation of T cells	R-HSA-9945266	5.139327e-02	1.289	0	0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	5.139327e-02	1.289	0	0
Activation of the pre-replicative complex	R-HSA-68962	5.220513e-02	1.282	0	0
SHC1 events in ERBB2 signaling	R-HSA-1250196	5.220513e-02	1.282	0	0
Downregulation of ERBB2 signaling	R-HSA-8863795	5.220513e-02	1.282	0	0
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	5.225812e-02	1.282	0	0
Loss of Function of SMAD4 in Cancer	R-HSA-3304347	6.019003e-02	1.220	0	0
SMAD2/3 MH2 Domain Mutants in Cancer	R-HSA-3315487	6.019003e-02	1.220	0	0
SMAD4 MH2 Domain Mutants in Cancer	R-HSA-3311021	6.019003e-02	1.220	0	0
Signaling by MRAS-complex mutants	R-HSA-9660537	5.924454e-02	1.227	0	0
Gain-of-function MRAS complexes activate RAF signaling	R-HSA-9726842	5.924454e-02	1.227	0	0
RUNX3 regulates p14-ARF	R-HSA-8951936	6.267306e-02	1.203	0	0
RUNX3 regulates NOTCH signaling	R-HSA-8941856	6.267306e-02	1.203	0	0
EGFR downregulation	R-HSA-182971	5.978931e-02	1.223	0	0
Interleukin-15 signaling	R-HSA-8983432	6.267306e-02	1.203	0	0
MITF-M-regulated melanocyte development	R-HSA-9730414	5.875393e-02	1.231	1	0
Oncogene Induced Senescence	R-HSA-2559585	5.507749e-02	1.259	1	1
Breakdown of the nuclear lamina	R-HSA-352238	6.019003e-02	1.220	0	0
HDMs demethylate histones	R-HSA-3214842	5.594019e-02	1.252	0	0
Signaling by Receptor Tyrosine Kinases	R-HSA-9006934	6.124750e-02	1.213	1	0
FLT3 Signaling	R-HSA-9607240	5.697108e-02	1.244	0	0
M-decay: degradation of maternal mRNAs by maternally stored factors	R-HSA-9820841	5.697108e-02	1.244	0	0
Long-term potentiation	R-HSA-9620244	5.594019e-02	1.252	0	0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	R-HSA-8866910	6.195089e-02	1.208	0	0
Signaling by FGFR1 in disease	R-HSA-5655302	6.384659e-02	1.195	0	0
Separation of Sister Chromatids	R-HSA-2467813	6.556047e-02	1.183	0	0
RUNX1 regulates transcription of genes involved in interleukin signaling	R-HSA-8939247	6.641516e-02	1.178	0	0
NFE2L2 regulating inflammation associated genes	R-HSA-9818026	6.641516e-02	1.178	0	0
IRS activation	R-HSA-74713	6.641516e-02	1.178	0	0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	R-HSA-9673768	6.641516e-02	1.178	0	0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	R-HSA-3134973	6.641516e-02	1.178	0	0
NrCAM interactions	R-HSA-447038	6.641516e-02	1.178	0	0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells	R-HSA-9937080	6.804473e-02	1.167	0	0
Apoptotic cleavage of cellular proteins	R-HSA-111465	6.804473e-02	1.167	0	0
Nuclear Receptor transcription pathway	R-HSA-383280	6.809058e-02	1.167	0	0
Transcriptional regulation by small RNAs	R-HSA-5578749	6.926081e-02	1.160	0	0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	R-HSA-9825892	6.941679e-02	1.159	0	0
ESR-mediated signaling	R-HSA-8939211	7.057302e-02	1.151	1	1
Kinesins	R-HSA-983189	7.105457e-02	1.148	0	0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	R-HSA-9029558	7.657630e-02	1.116	0	0
HDR through MMEJ (alt-NHEJ)	R-HSA-5685939	7.657630e-02	1.116	0	0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	R-HSA-8936459	8.325685e-02	1.080	0	0
Signaling by ERBB4	R-HSA-1236394	8.156842e-02	1.088	0	0
Regulation of HSF1-mediated heat shock response	R-HSA-3371453	7.719982e-02	1.112	1	1
Signaling by NOTCH3	R-HSA-9012852	7.860176e-02	1.105	0	0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	R-HSA-6804115	8.042880e-02	1.095	0	0
Regulation of cholesterol biosynthesis by SREBP (SREBF)	R-HSA-1655829	7.377554e-02	1.132	0	0
Interleukin-6 signaling	R-HSA-1059683	7.657630e-02	1.116	0	0
HDR through Single Strand Annealing (SSA)	R-HSA-5685938	7.697977e-02	1.114	0	0
Resolution of D-loop Structures through Holliday Junction Intermediates	R-HSA-5693568	7.697977e-02	1.114	0	0
Signaling by MET	R-HSA-6806834	7.976752e-02	1.098	0	0
Mitotic G1 phase and G1/S transition	R-HSA-453279	7.236829e-02	1.140	0	0
TGF-beta receptor signaling activates SMADs	R-HSA-2173789	7.915969e-02	1.101	0	0
Defective Intrinsic Pathway for Apoptosis	R-HSA-9734009	7.413117e-02	1.130	0	0
Synthesis of IP3 and IP4 in the cytosol	R-HSA-1855204	7.697977e-02	1.114	0	0
RNA Polymerase II Transcription	R-HSA-73857	8.378769e-02	1.077	1	0
NFE2L2 regulating anti-oxidant/detoxification enzymes	R-HSA-9818027	8.659826e-02	1.062	0	0
Resolution of D-Loop Structures	R-HSA-5693537	8.659826e-02	1.062	0	0
RUNX1 regulates expression of components of tight junctions	R-HSA-8935964	9.030094e-02	1.044	0	0
Negative feedback regulation of MAPK pathway	R-HSA-5674499	9.030094e-02	1.044	1	1
Signaling by RNF43 mutants	R-HSA-5340588	9.030094e-02	1.044	0	0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	R-HSA-446388	9.030094e-02	1.044	0	0
Regulation of KIT signaling	R-HSA-1433559	9.200070e-02	1.036	0	0
Response of EIF2AK1 (HRI) to heme deficiency	R-HSA-9648895	9.239180e-02	1.034	0	0
MET activates RAP1 and RAC1	R-HSA-8875555	9.483604e-02	1.023	0	0
Establishment of Sister Chromatid Cohesion	R-HSA-2468052	9.483604e-02	1.023	0	0
Signal attenuation	R-HSA-74749	9.483604e-02	1.023	1	1
Formation of intermediate mesoderm	R-HSA-9761174	9.483604e-02	1.023	0	0
Signaling by Leptin	R-HSA-2586552	9.483604e-02	1.023	0	0
RAF activation	R-HSA-5673000	9.689945e-02	1.014	0	0
Diseases of DNA Double-Strand Break Repair	R-HSA-9675136	9.689945e-02	1.014	0	0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function	R-HSA-9701190	9.689945e-02	1.014	0	0
Regulation of TP53 Expression	R-HSA-6804754	9.836014e-02	1.007	0	0
L1CAM interactions	R-HSA-373760	9.943819e-02	1.002	1	0
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	1.052922e-01	0.978	0	0
Interleukin-6 family signaling	R-HSA-6783589	1.052922e-01	0.978	0	0
Neurodegenerative Diseases	R-HSA-8863678	1.052922e-01	0.978	0	0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	R-HSA-8862803	1.052922e-01	0.978	0	0
Diseases of DNA repair	R-HSA-9675135	1.060949e-01	0.974	0	0
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-5693616	1.078780e-01	0.967	0	0
Signalling to ERKs	R-HSA-187687	1.078780e-01	0.967	1	0
Signaling by BRAF and RAF1 fusions	R-HSA-6802952	1.083351e-01	0.965	1	1
APC truncation mutants are not K63 polyubiquitinated	R-HSA-5467333	1.233580e-01	0.909	0	0
Deletions in the AXIN1 gene destabilize the destruction complex	R-HSA-5467345	1.233580e-01	0.909	0	0
Defective translocation of RB1 mutants to the nucleus	R-HSA-9661070	1.233580e-01	0.909	0	0
Loss of function of TP53 in cancer due to loss of tetramerization ability	R-HSA-9723905	1.233580e-01	0.909	0	0
Loss of Function of TP53 in Cancer	R-HSA-9723907	1.233580e-01	0.909	0	0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	R-HSA-8869496	1.172001e-01	0.931	0	0
RUNX1 regulates transcription of genes involved in WNT signaling	R-HSA-8939256	1.172001e-01	0.931	0	0
RUNX3 regulates YAP1-mediated transcription	R-HSA-8951671	1.172001e-01	0.931	0	0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	R-HSA-5693554	1.191077e-01	0.924	0	0
RNA Polymerase I Transcription Initiation	R-HSA-73762	1.294853e-01	0.888	0	0
RNA Polymerase II Transcription Termination	R-HSA-73856	1.299572e-01	0.886	0	0
Prolonged ERK activation events	R-HSA-169893	1.271695e-01	0.896	1	0
Golgi-to-ER retrograde transport	R-HSA-8856688	1.285077e-01	0.891	0	0
Negative regulation of MAPK pathway	R-HSA-5675221	1.181215e-01	0.928	1	1
G2/M DNA damage checkpoint	R-HSA-69473	1.309355e-01	0.883	0	0
RNA Polymerase II Pre-transcription Events	R-HSA-674695	1.309355e-01	0.883	0	0
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	1.197855e-01	0.922	0	0
Regulation of beta-cell development	R-HSA-186712	1.111198e-01	0.954	0	0
Receptor-type tyrosine-protein phosphatases	R-HSA-388844	1.271695e-01	0.896	0	0
Defective Mismatch Repair Associated With MLH1	R-HSA-5545483	2.315051e-01	0.635	0	0
Impaired BRCA2 binding to SEM1 (DSS1)	R-HSA-9763198	2.315051e-01	0.635	0	0
Defective Mismatch Repair Associated With PMS2	R-HSA-5632987	2.315051e-01	0.635	0	0
Defective Mismatch Repair Associated With MSH6	R-HSA-5632968	2.315051e-01	0.635	0	0
Impaired BRCA2 translocation to the nucleus	R-HSA-9709275	2.315051e-01	0.635	0	0
Defective DNA double strand break response due to BARD1 loss of function	R-HSA-9699150	2.315051e-01	0.635	0	0
Defective DNA double strand break response due to BRCA1 loss of function	R-HSA-9663199	2.315051e-01	0.635	0	0
MET interacts with TNS proteins	R-HSA-8875513	1.414162e-01	0.850	0	0
Regulation of gap junction activity	R-HSA-191650	1.875733e-01	0.727	0	0
PLCG1 events in ERBB2 signaling	R-HSA-1251932	1.875733e-01	0.727	0	0
Inhibition of TSC complex formation by PKB	R-HSA-165181	1.875733e-01	0.727	0	0
ARL13B-mediated ciliary trafficking of INPP5E	R-HSA-5624958	3.263161e-01	0.486	0	0
Nef mediated downregulation of CD28 cell surface expression	R-HSA-164939	3.263161e-01	0.486	0	0
Defective VWF binding to collagen type I	R-HSA-9845622	3.263161e-01	0.486	0	0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	R-HSA-5619101	3.263161e-01	0.486	0	0
Signaling by TCF7L2 mutants	R-HSA-5339700	3.263161e-01	0.486	0	0
Intestinal infectious diseases	R-HSA-8942233	3.263161e-01	0.486	0	0
Defective SLC9A9 causes autism 16 (AUTS16)	R-HSA-5619052	3.263161e-01	0.486	0	0
Defective MMADHC causes MMAHCD	R-HSA-3359473	3.263161e-01	0.486	0	0
PTEN Loss of Function in Cancer	R-HSA-5674404	3.263161e-01	0.486	0	0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	R-HSA-5660686	3.263161e-01	0.486	0	0
RUNX1 regulates estrogen receptor mediated transcription	R-HSA-8931987	1.466605e-01	0.834	0	0
Regulation of PTEN localization	R-HSA-8948747	1.466605e-01	0.834	0	0
PTK6 Expression	R-HSA-8849473	1.466605e-01	0.834	0	0
Cohesin Loading onto Chromatin	R-HSA-2470946	1.466605e-01	0.834	0	0
SOS-mediated signalling	R-HSA-112412	1.466605e-01	0.834	0	0
SMAC (DIABLO) binds to IAPs	R-HSA-111463	2.354119e-01	0.628	0	0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	R-HSA-111464	2.354119e-01	0.628	0	0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence	R-HSA-9825895	1.782150e-01	0.749	0	0
Downregulation of ERBB4 signaling	R-HSA-1253288	1.782150e-01	0.749	0	0
MET receptor recycling	R-HSA-8875656	1.782150e-01	0.749	0	0
Regulation of gene expression by Hypoxia-inducible Factor	R-HSA-1234158	1.382708e-01	0.859	0	0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis	R-HSA-9623433	1.382708e-01	0.859	0	0
Anchoring fibril formation	R-HSA-2214320	1.382708e-01	0.859	0	0
Inhibition of replication initiation of damaged DNA by RB1/E2F1	R-HSA-113501	1.382708e-01	0.859	0	0
Signaling by AXIN mutants	R-HSA-4839735	1.382708e-01	0.859	0	0
NOTCH2 intracellular domain regulates transcription	R-HSA-2197563	1.624918e-01	0.789	0	0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	R-HSA-9820865	1.624918e-01	0.789	0	0
GP1b-IX-V activation signalling	R-HSA-430116	2.114021e-01	0.675	0	0
NFE2L2 regulating MDR associated enzymes	R-HSA-9818032	2.114021e-01	0.675	0	0
ALK mutants bind TKIs	R-HSA-9700645	2.114021e-01	0.675	0	0
SMAC, XIAP-regulated apoptotic response	R-HSA-111469	2.838155e-01	0.547	0	0
Epithelial-Mesenchymal Transition (EMT) during gastrulation	R-HSA-9758919	2.838155e-01	0.547	0	0
Noncanonical activation of NOTCH3	R-HSA-9017802	2.838155e-01	0.547	0	0
Loss of Function of SMAD2/3 in Cancer	R-HSA-3304349	2.838155e-01	0.547	0	0
Activation of caspases through apoptosome-mediated cleavage	R-HSA-111459	2.838155e-01	0.547	0	0
CDC6 association with the ORC:origin complex	R-HSA-68689	2.838155e-01	0.547	0	0
Drug resistance in ERBB2 KD mutants	R-HSA-9665230	4.094349e-01	0.388	0	0
Drug-mediated inhibition of ERBB2 signaling	R-HSA-9652282	4.094349e-01	0.388	0	0
Glycogen storage disease type IV (GBE1)	R-HSA-3878781	4.094349e-01	0.388	0	0
Resistance of ERBB2 KD mutants to sapitinib	R-HSA-9665244	4.094349e-01	0.388	0	0
Defective VWF cleavage by ADAMTS13 variant	R-HSA-9845621	4.094349e-01	0.388	0	0
Resistance of ERBB2 KD mutants to tesevatinib	R-HSA-9665245	4.094349e-01	0.388	0	0
Resistance of ERBB2 KD mutants to trastuzumab	R-HSA-9665233	4.094349e-01	0.388	0	0
Resistance of ERBB2 KD mutants to AEE788	R-HSA-9665250	4.094349e-01	0.388	0	0
Resistance of ERBB2 KD mutants to afatinib	R-HSA-9665249	4.094349e-01	0.388	0	0
Defective F8 sulfation at Y1699	R-HSA-9674519	4.094349e-01	0.388	0	0
Resistance of ERBB2 KD mutants to osimertinib	R-HSA-9665247	4.094349e-01	0.388	0	0
Drug resistance in ERBB2 TMD/JMD mutants	R-HSA-9665737	4.094349e-01	0.388	0	0
Enhanced cleavage of VWF variant by ADAMTS13	R-HSA-9845619	4.094349e-01	0.388	0	0
Resistance of ERBB2 KD mutants to lapatinib	R-HSA-9665251	4.094349e-01	0.388	0	0
Resistance of ERBB2 KD mutants to neratinib	R-HSA-9665246	4.094349e-01	0.388	0	0
Processing of Intronless Pre-mRNAs	R-HSA-77595	1.467450e-01	0.833	0	0
SHC1 events in ERBB4 signaling	R-HSA-1250347	1.467450e-01	0.833	0	0
CD28 dependent Vav1 pathway	R-HSA-389359	1.881088e-01	0.726	0	0
Regulation of MITF-M-dependent genes involved in apoptosis	R-HSA-9824594	1.322123e-01	0.879	0	0
DNA replication initiation	R-HSA-68952	2.457801e-01	0.609	0	0
Regulation of CDH1 mRNA translation by microRNAs	R-HSA-9764562	2.149045e-01	0.668	0	0
PTK6 promotes HIF1A stabilization	R-HSA-8857538	3.319171e-01	0.479	0	0
G2/M DNA replication checkpoint	R-HSA-69478	3.319171e-01	0.479	0	0
Signaling by APC mutants	R-HSA-4839744	2.809369e-01	0.551	0	0
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	2.809369e-01	0.551	0	0
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	2.809369e-01	0.551	0	0
Truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	2.809369e-01	0.551	0	0
Processive synthesis on the lagging strand	R-HSA-69183	2.426596e-01	0.615	0	0
E2F mediated regulation of DNA replication	R-HSA-113510	2.121295e-01	0.673	0	0
Signaling by high-kinase activity BRAF mutants	R-HSA-6802948	1.318241e-01	0.880	1	1
Developmental Lineage of Mammary Gland Myoepithelial Cells	R-HSA-9927432	1.828078e-01	0.738	0	0
NFE2L2 regulates pentose phosphate pathway genes	R-HSA-9818028	3.164964e-01	0.500	0	0
PI3K events in ERBB4 signaling	R-HSA-1250342	3.164964e-01	0.500	0	0
Signaling by GSK3beta mutants	R-HSA-5339716	3.164964e-01	0.500	0	0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	R-HSA-2892245	3.790549e-01	0.421	0	0
NOSTRIN mediated eNOS trafficking	R-HSA-203641	3.790549e-01	0.421	0	0
IFNG signaling activates MAPKs	R-HSA-9732724	3.790549e-01	0.421	1	1
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis	R-HSA-9632974	3.790549e-01	0.421	0	0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose	R-HSA-9031528	3.790549e-01	0.421	0	0
Recycling of eIF2:GDP	R-HSA-72731	3.790549e-01	0.421	0	0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake	R-HSA-9031525	3.790549e-01	0.421	0	0
MET activates STAT3	R-HSA-8875791	4.823027e-01	0.317	0	0
Activation of BIM and translocation to mitochondria	R-HSA-111446	4.823027e-01	0.317	0	0
Defective MMACHC causes MAHCC	R-HSA-3359474	4.823027e-01	0.317	0	0
Signaling by plasma membrane FGFR1 fusions	R-HSA-8853336	4.823027e-01	0.317	0	0
Classical Kir channels	R-HSA-1296053	4.823027e-01	0.317	0	0
MET activates PTPN11	R-HSA-8865999	4.823027e-01	0.317	0	0
Defective DPM2 causes DPM2-CDG	R-HSA-4719377	4.823027e-01	0.317	0	0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome	R-HSA-9944997	4.823027e-01	0.317	0	0
Signalling to STAT3	R-HSA-198745	4.823027e-01	0.317	0	0
Loss of Function of KMT2D in Kabuki Syndrome	R-HSA-9944971	4.823027e-01	0.317	0	0
Defective DPM1 causes DPM1-CDG	R-HSA-4717374	4.823027e-01	0.317	0	0
Defective DPM3 causes DPM3-CDG	R-HSA-4719360	4.823027e-01	0.317	0	0
NOTCH4 Intracellular Domain Regulates Transcription	R-HSA-9013695	2.600072e-01	0.585	0	0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	R-HSA-73779	1.724432e-01	0.763	0	0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	R-HSA-2892247	3.001858e-01	0.523	0	0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	R-HSA-141405	3.001858e-01	0.523	0	0
Inactivation of APC/C via direct inhibition of the APC/C complex	R-HSA-141430	3.001858e-01	0.523	0	0
Constitutive Signaling by Overexpressed ERBB2	R-HSA-9634285	3.521215e-01	0.453	0	0
Polymerase switching	R-HSA-69091	3.521215e-01	0.453	0	0
Leading Strand Synthesis	R-HSA-69109	3.521215e-01	0.453	0	0
Signaling by CTNNB1 phospho-site mutants	R-HSA-4839743	3.521215e-01	0.453	0	0
CTNNB1 S33 mutants aren't phosphorylated	R-HSA-5358747	3.521215e-01	0.453	0	0
CTNNB1 S37 mutants aren't phosphorylated	R-HSA-5358749	3.521215e-01	0.453	0	0
CTNNB1 T41 mutants aren't phosphorylated	R-HSA-5358752	3.521215e-01	0.453	0	0
CTNNB1 S45 mutants aren't phosphorylated	R-HSA-5358751	3.521215e-01	0.453	0	0
Paradoxical activation of RAF signaling by kinase inactive BRAF	R-HSA-6802955	1.804193e-01	0.744	1	1
Signaling by moderate kinase activity BRAF mutants	R-HSA-6802946	1.804193e-01	0.744	1	1
Signaling downstream of RAS mutants	R-HSA-9649948	1.804193e-01	0.744	1	1
MAP2K and MAPK activation	R-HSA-5674135	2.023575e-01	0.694	1	1
RNA Polymerase II HIV Promoter Escape	R-HSA-167162	2.023575e-01	0.694	0	0
Signaling by RAF1 mutants	R-HSA-9656223	2.023575e-01	0.694	1	1
HIV Transcription Initiation	R-HSA-167161	2.023575e-01	0.694	0	0
RNA Polymerase II Transcription Initiation	R-HSA-75953	2.023575e-01	0.694	0	0
mRNA 3'-end processing	R-HSA-72187	1.738518e-01	0.760	0	0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	R-HSA-8939246	4.247348e-01	0.372	0	0
Type I hemidesmosome assembly	R-HSA-446107	4.247348e-01	0.372	0	0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	R-HSA-77588	4.247348e-01	0.372	0	0
Formation of annular gap junctions	R-HSA-196025	4.247348e-01	0.372	0	0
Regulation of NPAS4 mRNA translation	R-HSA-9768778	4.247348e-01	0.372	0	0
Meiotic synapsis	R-HSA-1221632	1.868092e-01	0.729	0	0
RNA Polymerase III Transcription Initiation From Type 3 Promoter	R-HSA-76071	3.100785e-01	0.509	0	0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)	R-HSA-9845323	1.919788e-01	0.717	0	0
RNA Polymerase II Promoter Escape	R-HSA-73776	2.342349e-01	0.630	0	0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	R-HSA-9926550	3.590471e-01	0.445	0	0
Signaling by ERBB2 ECD mutants	R-HSA-9665348	3.590471e-01	0.445	0	0
Interleukin receptor SHC signaling	R-HSA-912526	3.356093e-01	0.474	0	0
RNA Polymerase II Transcription Initiation And Promoter Clearance	R-HSA-76042	2.677713e-01	0.572	0	0
Processing of DNA double-strand break ends	R-HSA-5693607	2.024555e-01	0.694	0	0
RNA polymerase II transcribes snRNA genes	R-HSA-6807505	1.939382e-01	0.712	0	0
COPI-dependent Golgi-to-ER retrograde traffic	R-HSA-6811434	1.783393e-01	0.749	0	0
Regulation of signaling by CBL	R-HSA-912631	3.885158e-01	0.411	0	0
Abortive elongation of HIV-1 transcript in the absence of Tat	R-HSA-167242	3.885158e-01	0.411	0	0
Removal of the Flap Intermediate	R-HSA-69166	4.224213e-01	0.374	0	0
ARMS-mediated activation	R-HSA-170984	4.685992e-01	0.329	0	0
Gap junction degradation	R-HSA-190873	4.685992e-01	0.329	0	0
HCN channels	R-HSA-1296061	5.461834e-01	0.263	0	0
TGFBR1 KD Mutants in Cancer	R-HSA-3656532	5.461834e-01	0.263	0	0
Signaling by MAP2K mutants	R-HSA-9652169	5.461834e-01	0.263	1	1
Defective LFNG causes SCDO3	R-HSA-5083630	5.461834e-01	0.263	0	0
Signaling by LRP5 mutants	R-HSA-5339717	5.461834e-01	0.263	0	0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	R-HSA-69200	5.461834e-01	0.263	0	0
RNA Polymerase III Abortive And Retractive Initiation	R-HSA-749476	3.393612e-01	0.469	0	0
AURKA Activation by TPX2	R-HSA-8854518	2.740017e-01	0.562	0	0
Erythropoietin activates RAS	R-HSA-9027284	4.566211e-01	0.340	0	0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	R-HSA-450513	4.566211e-01	0.340	0	0
Beta-catenin phosphorylation cascade	R-HSA-196299	4.566211e-01	0.340	0	0
Regulation of RUNX1 Expression and Activity	R-HSA-8934593	4.127174e-01	0.384	0	0
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	3.357229e-01	0.474	0	0
Loss of Nlp from mitotic centrosomes	R-HSA-380259	3.357229e-01	0.474	0	0
Lagging Strand Synthesis	R-HSA-69186	4.467310e-01	0.350	0	0
APC-Cdc20 mediated degradation of Nek2A	R-HSA-179409	4.467310e-01	0.350	0	0
MAPK3 (ERK1) activation	R-HSA-110056	5.104008e-01	0.292	1	1
Activation of Ca-permeable Kainate Receptor	R-HSA-451308	5.104008e-01	0.292	0	0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	R-HSA-2151209	5.104008e-01	0.292	0	0
Interaction between L1 and Ankyrins	R-HSA-445095	4.382233e-01	0.358	0	0
PPARA activates gene expression	R-HSA-1989781	2.752674e-01	0.560	0	0
Formation of RNA Pol II elongation complex	R-HSA-112382	3.933518e-01	0.405	0	0
Defective GALNT12 causes CRCS1	R-HSA-5083636	4.899334e-01	0.310	0	0
Defective GALNT3 causes HFTC	R-HSA-5083625	4.899334e-01	0.310	0	0
Condensation of Prophase Chromosomes	R-HSA-2299718	4.175850e-01	0.379	0	0
mRNA Splicing - Minor Pathway	R-HSA-72165	4.175850e-01	0.379	0	0
Unblocking of NMDA receptors, glutamate binding and activation	R-HSA-438066	4.752052e-01	0.323	0	0
Ras activation upon Ca2+ influx through NMDA receptor	R-HSA-442982	4.752052e-01	0.323	0	0
RNA Polymerase II Transcription Elongation	R-HSA-75955	4.117601e-01	0.385	0	0
Formation of the HIV-1 Early Elongation Complex	R-HSA-167158	4.634659e-01	0.334	0	0
Formation of the Early Elongation Complex	R-HSA-113418	4.634659e-01	0.334	0	0
HIV elongation arrest and recovery	R-HSA-167287	4.634659e-01	0.334	0	0
Pausing and recovery of HIV elongation	R-HSA-167290	4.634659e-01	0.334	0	0
Developmental Lineage of Pancreatic Ductal Cells	R-HSA-9925563	4.341661e-01	0.362	0	0
Late endosomal microautophagy	R-HSA-9615710	4.883588e-01	0.311	0	0
G beta:gamma signalling through CDC42	R-HSA-8964616	5.222102e-01	0.282	0	0
Formation of the posterior neural plate	R-HSA-9832991	5.499809e-01	0.260	0	0
Regulation of CDH11 mRNA translation by microRNAs	R-HSA-9759811	5.499809e-01	0.260	0	0
Regulation of MITF-M dependent genes involved in invasion	R-HSA-9854909	6.021848e-01	0.220	0	0
NFE2L2 regulating TCA cycle genes	R-HSA-9818025	6.021848e-01	0.220	0	0
RUNX1 regulates transcription of genes involved in BCR signaling	R-HSA-8939245	6.021848e-01	0.220	0	0
NOSIP mediated eNOS trafficking	R-HSA-203754	6.021848e-01	0.220	0	0
G2 Phase	R-HSA-68911	6.021848e-01	0.220	0	0
FLT3 signaling by CBL mutants	R-HSA-9706377	6.021848e-01	0.220	0	0
Enhanced binding of GP1BA variant to VWF multimer:collagen	R-HSA-9845620	6.021848e-01	0.220	0	0
Defective binding of VWF variant to GPIb:IX:V	R-HSA-9846298	6.021848e-01	0.220	0	0
SMAD2/3 Phosphorylation Motif Mutants in Cancer	R-HSA-3304356	6.021848e-01	0.220	0	0
NR1H2 and NR1H3-mediated signaling	R-HSA-9024446	4.435176e-01	0.353	0	0
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	5.128242e-01	0.290	0	0
RNA Pol II CTD phosphorylation and interaction with CE	R-HSA-77075	5.303251e-01	0.275	0	0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	R-HSA-167160	5.303251e-01	0.275	0	0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	R-HSA-9029569	5.029240e-01	0.298	0	0
Removal of the Flap Intermediate from the C-strand	R-HSA-174437	5.533348e-01	0.257	0	0
Defective C1GALT1C1 causes TNPS	R-HSA-5083632	5.533348e-01	0.257	0	0
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	4.996329e-01	0.301	0	0
Centrosome maturation	R-HSA-380287	5.316751e-01	0.274	0	0
Nucleosome assembly	R-HSA-774815	5.471842e-01	0.262	0	0
Deposition of new CENPA-containing nucleosomes at the centromere	R-HSA-606279	5.471842e-01	0.262	0	0
Diseases of mitotic cell cycle	R-HSA-9675126	5.602047e-01	0.252	0	0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	R-HSA-442742	5.830071e-01	0.234	1	0
Inhibition of DNA recombination at telomere	R-HSA-9670095	5.842435e-01	0.233	0	0
Formation of HIV elongation complex in the absence of HIV Tat	R-HSA-167152	5.842435e-01	0.233	0	0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	R-HSA-9027276	6.221793e-01	0.206	0	0
GRB2 events in EGFR signaling	R-HSA-179812	6.221793e-01	0.206	0	0
Defects of platelet adhesion to exposed collagen	R-HSA-9823587	6.512785e-01	0.186	0	0
SLIT2:ROBO1 increases RHOA activity	R-HSA-8985586	6.512785e-01	0.186	0	0
Inhibition of Signaling by Overexpressed EGFR	R-HSA-5638303	6.512785e-01	0.186	0	0
PKB-mediated events	R-HSA-109703	6.512785e-01	0.186	0	0
PDE3B signalling	R-HSA-165160	6.512785e-01	0.186	0	0
Signaling by Overexpressed Wild-Type EGFR in Cancer	R-HSA-5638302	6.512785e-01	0.186	0	0
Phosphorylation of Emi1	R-HSA-176417	6.512785e-01	0.186	0	0
Loss of MECP2 binding ability to the NCoR/SMRT complex	R-HSA-9022537	6.512785e-01	0.186	0	0
Loss-of-function mutations in DBT cause MSUD2	R-HSA-9865113	6.512785e-01	0.186	0	0
Loss-of-function mutations in DLD cause MSUD3/DLDD	R-HSA-9907570	6.512785e-01	0.186	0	0
Signaling by MAPK mutants	R-HSA-9652817	6.512785e-01	0.186	0	0
Recruitment of NuMA to mitotic centrosomes	R-HSA-380320	6.236822e-01	0.205	0	0
COPI-mediated anterograde transport	R-HSA-6807878	6.507089e-01	0.187	0	0
Processive synthesis on the C-strand of the telomere	R-HSA-174414	6.310434e-01	0.200	0	0
TNFR1-induced NF-kappa-B signaling pathway	R-HSA-5357956	6.310434e-01	0.200	0	0
Tat-mediated HIV elongation arrest and recovery	R-HSA-167243	6.310434e-01	0.200	0	0
Pausing and recovery of Tat-mediated HIV elongation	R-HSA-167238	6.310434e-01	0.200	0	0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	R-HSA-8877330	6.547754e-01	0.184	0	0
Golgi Cisternae Pericentriolar Stack Reorganization	R-HSA-162658	6.547754e-01	0.184	0	0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	R-HSA-75035	6.547754e-01	0.184	0	0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	R-HSA-9659787	6.547754e-01	0.184	0	0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	R-HSA-9661069	6.547754e-01	0.184	0	0
PTEN Regulation	R-HSA-6807070	2.489975e-01	0.604	1	0
Transcription of the HIV genome	R-HSA-167172	3.035915e-01	0.518	0	0
Regulation of lipid metabolism by PPARalpha	R-HSA-400206	2.291842e-01	0.640	0	0
Signaling by EGFR in Cancer	R-HSA-1643713	6.071997e-01	0.217	0	0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	R-HSA-9818564	2.305856e-01	0.637	0	0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes	R-HSA-9851695	2.305856e-01	0.637	0	0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	R-HSA-9841922	2.305856e-01	0.637	0	0
RNA Polymerase III Transcription	R-HSA-74158	3.393612e-01	0.469	0	0
Degradation of beta-catenin by the destruction complex	R-HSA-195253	3.339739e-01	0.476	0	0
Signaling by Ligand-Responsive EGFR Variants in Cancer	R-HSA-5637815	4.467310e-01	0.350	0	0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	R-HSA-1236382	4.467310e-01	0.350	0	0
Transcriptional regulation of testis differentiation	R-HSA-9690406	3.001858e-01	0.523	0	0
Constitutive Signaling by EGFRvIII	R-HSA-5637810	3.295454e-01	0.482	0	0
Signaling by EGFRvIII in Cancer	R-HSA-5637812	3.295454e-01	0.482	0	0
Transcriptional regulation of pluripotent stem cells	R-HSA-452723	1.447592e-01	0.839	0	0
Aggrephagy	R-HSA-9646399	5.842435e-01	0.233	0	0
RNA Polymerase III Transcription Initiation	R-HSA-76046	3.383833e-01	0.471	0	0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	R-HSA-5693565	5.207314e-01	0.283	0	0
Crosslinking of collagen fibrils	R-HSA-2243919	6.117968e-01	0.213	0	0
FOXO-mediated transcription of cell cycle genes	R-HSA-9617828	2.848349e-01	0.545	0	0
Activation of gene expression by SREBF (SREBP)	R-HSA-2426168	1.504656e-01	0.823	0	0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	R-HSA-5358565	5.533348e-01	0.257	0	0
DNA Double Strand Break Response	R-HSA-5693606	6.533133e-01	0.185	0	0
PTK6 Activates STAT3	R-HSA-8849474	2.354119e-01	0.628	0	0
Regulation of FOXO transcriptional activity by acetylation	R-HSA-9617629	1.624918e-01	0.789	0	0
p75NTR recruits signalling complexes	R-HSA-209543	3.521215e-01	0.453	0	0
Downregulation of SMAD2/3:SMAD4 transcriptional activity	R-HSA-2173795	2.380528e-01	0.623	1	1
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	1.662680e-01	0.779	0	0
Regulation of endogenous retroelements	R-HSA-9842860	3.237119e-01	0.490	0	0
mTORC1-mediated signalling	R-HSA-166208	3.100785e-01	0.509	0	0
Homology Directed Repair	R-HSA-5693538	1.597266e-01	0.797	0	0
Chromosome Maintenance	R-HSA-73886	6.053211e-01	0.218	0	0
DNA strand elongation	R-HSA-69190	5.602047e-01	0.252	0	0
Rap1 signalling	R-HSA-392517	2.121295e-01	0.673	0	0
TP53 Regulates Transcription of Death Receptors and Ligands	R-HSA-6803211	4.224213e-01	0.374	0	0
Disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	4.382233e-01	0.358	0	0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	R-HSA-5693567	2.303016e-01	0.638	0	0
Signaling by ERBB2	R-HSA-1227986	1.919788e-01	0.717	0	0
Frs2-mediated activation	R-HSA-170968	1.881088e-01	0.726	1	1
EPHB-mediated forward signaling	R-HSA-3928662	5.272970e-01	0.278	0	0
Assembly of collagen fibrils and other multimeric structures	R-HSA-2022090	5.207314e-01	0.283	0	0
Neurexins and neuroligins	R-HSA-6794361	3.933518e-01	0.405	0	0
DNA Damage/Telomere Stress Induced Senescence	R-HSA-2559586	2.180085e-01	0.662	0	0
Regulation of the apoptosome activity	R-HSA-9627069	5.104008e-01	0.292	1	1
Telomere C-strand (Lagging Strand) Synthesis	R-HSA-174417	4.658497e-01	0.332	0	0
Cytochrome c-mediated apoptotic response	R-HSA-111461	5.872513e-01	0.231	1	0
Nephron development	R-HSA-9831926	5.832184e-01	0.234	0	0
Signaling by BMP	R-HSA-201451	6.310434e-01	0.200	0	0
DNA Double-Strand Break Repair	R-HSA-5693532	4.043045e-01	0.393	0	0
TRAF3-dependent IRF activation pathway	R-HSA-918233	5.222102e-01	0.282	0	0
Signaling by WNT in cancer	R-HSA-4791275	1.334169e-01	0.875	0	0
Formation of lateral plate mesoderm	R-HSA-9758920	2.838155e-01	0.547	0	0
Regulation of CDH19 Expression and Function	R-HSA-9764302	2.838155e-01	0.547	0	0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	R-HSA-6803204	2.706534e-01	0.568	0	0
Nuclear RNA decay	R-HSA-9930044	2.575707e-01	0.589	0	0
Activation of the AP-1 family of transcription factors	R-HSA-450341	4.685992e-01	0.329	1	1
Signaling by Activin	R-HSA-1502540	4.566211e-01	0.340	1	1
Formation of apoptosome	R-HSA-111458	5.104008e-01	0.292	1	0
PI3K/AKT activation	R-HSA-198203	5.104008e-01	0.292	0	0
activated TAK1 mediates p38 MAPK activation	R-HSA-450302	4.752052e-01	0.323	0	0
G2/M Checkpoints	R-HSA-69481	3.261338e-01	0.487	0	0
Pre-NOTCH Expression and Processing	R-HSA-1912422	5.783694e-01	0.238	0	0
Signaling by RAS mutants	R-HSA-6802949	1.804193e-01	0.744	1	0
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	4.224213e-01	0.374	0	0
Sensing of DNA Double Strand Breaks	R-HSA-5693548	5.872513e-01	0.231	0	0
PIP3 activates AKT signaling	R-HSA-1257604	1.360252e-01	0.866	1	0
Intra-Golgi and retrograde Golgi-to-ER traffic	R-HSA-6811442	3.004760e-01	0.522	0	0
p75NTR signals via NF-kB	R-HSA-193639	4.566211e-01	0.340	0	0
Mismatch Repair	R-HSA-5358508	5.832184e-01	0.234	0	0
FOXO-mediated transcription	R-HSA-9614085	5.861379e-01	0.232	0	0
Insulin receptor signalling cascade	R-HSA-74751	6.059929e-01	0.218	1	0
MTOR signalling	R-HSA-165159	2.180691e-01	0.661	0	0
Mitotic Telophase/Cytokinesis	R-HSA-68884	1.382708e-01	0.859	0	0
GLI proteins bind promoters of Hh responsive genes to promote transcription	R-HSA-5635851	2.838155e-01	0.547	0	0
CREB phosphorylation	R-HSA-199920	3.319171e-01	0.479	0	0
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	1.828078e-01	0.738	1	0
Adrenoceptors	R-HSA-390696	4.247348e-01	0.372	0	0
Formation of axial mesoderm	R-HSA-9796292	3.875154e-01	0.412	0	0
TFAP2 (AP-2) family regulates transcription of cell cycle factors	R-HSA-8866911	5.461834e-01	0.263	0	0
HDR through Homologous Recombination (HRR)	R-HSA-5685942	2.886845e-01	0.540	0	0
RNA Polymerase I Transcription Termination	R-HSA-73863	4.382233e-01	0.358	0	0
Meiosis	R-HSA-1500620	3.441938e-01	0.463	0	0
Regulation of TP53 Activity through Methylation	R-HSA-6804760	5.832184e-01	0.234	0	0
Activation of HOX genes during differentiation	R-HSA-5619507	3.619252e-01	0.441	0	0
Activation of anterior HOX genes in hindbrain development during early embryogenesis	R-HSA-5617472	3.619252e-01	0.441	0	0
Laminin interactions	R-HSA-3000157	5.824351e-01	0.235	0	0
Interleukin-35 Signalling	R-HSA-8984722	3.521215e-01	0.453	0	0
Transcriptional and post-translational regulation of MITF-M expression and activity	R-HSA-9856649	2.474423e-01	0.607	1	1
Pre-NOTCH Transcription and Translation	R-HSA-1912408	3.415702e-01	0.467	0	0
Germ layer formation at gastrulation	R-HSA-9754189	3.885158e-01	0.411	0	0
Signaling by NOTCH	R-HSA-157118	2.269714e-01	0.644	0	0
Oxidative Stress Induced Senescence	R-HSA-2559580	3.237119e-01	0.490	1	1
Initiation of Nuclear Envelope (NE) Reformation	R-HSA-2995383	2.848349e-01	0.545	0	0
IL-6-type cytokine receptor ligand interactions	R-HSA-6788467	3.875154e-01	0.412	0	0
ERK/MAPK targets	R-HSA-198753	4.467310e-01	0.350	1	1
Signaling by CSF1 (M-CSF) in myeloid cells	R-HSA-9680350	4.535670e-01	0.343	0	0
Positive epigenetic regulation of rRNA expression	R-HSA-5250913	4.670637e-01	0.331	0	0
Activated NTRK2 signals through FRS2 and FRS3	R-HSA-9028731	6.221793e-01	0.206	0	0
Nuclear Envelope (NE) Reassembly	R-HSA-2995410	3.766055e-01	0.424	0	0
Homologous DNA Pairing and Strand Exchange	R-HSA-5693579	1.447592e-01	0.839	0	0
MET activates RAS signaling	R-HSA-8851805	3.521215e-01	0.453	0	0
Interleukin-2 family signaling	R-HSA-451927	1.724432e-01	0.763	0	0
Mitochondrial biogenesis	R-HSA-1592230	2.111172e-01	0.675	0	0
TCF dependent signaling in response to WNT	R-HSA-201681	2.780551e-01	0.556	0	0
Organelle biogenesis and maintenance	R-HSA-1852241	2.333972e-01	0.632	0	0
Interleukin-4 and Interleukin-13 signaling	R-HSA-6785807	5.088265e-01	0.293	0	0
Cilium Assembly	R-HSA-5617833	4.133500e-01	0.384	0	0
Generic Transcription Pathway	R-HSA-212436	1.461030e-01	0.835	1	0
Diseases of Mismatch Repair (MMR)	R-HSA-5423599	1.414162e-01	0.850	0	0
Calcineurin activates NFAT	R-HSA-2025928	2.114021e-01	0.675	0	0
Activation of ATR in response to replication stress	R-HSA-176187	1.475375e-01	0.831	0	0
Polymerase switching on the C-strand of the telomere	R-HSA-174411	2.275491e-01	0.643	0	0
MET promotes cell motility	R-HSA-8875878	2.454692e-01	0.610	0	0
Retrograde neurotrophin signalling	R-HSA-177504	4.224213e-01	0.374	0	0
Negative regulation of MET activity	R-HSA-6807004	4.177918e-01	0.379	0	0
Signaling by NODAL	R-HSA-1181150	4.177918e-01	0.379	1	1
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	3.766055e-01	0.424	0	0
mRNA decay by 5' to 3' exoribonuclease	R-HSA-430039	5.222102e-01	0.282	0	0
Resolution of AP sites via the single-nucleotide replacement pathway	R-HSA-110381	6.021848e-01	0.220	0	0
Post-transcriptional silencing by small RNAs	R-HSA-426496	6.021848e-01	0.220	0	0
Signaling by Nuclear Receptors	R-HSA-9006931	3.757659e-01	0.425	1	0
Reduction of cytosolic Ca++ levels	R-HSA-418359	5.872513e-01	0.231	0	0
IRS-mediated signalling	R-HSA-112399	6.221987e-01	0.206	0	0
Membrane Trafficking	R-HSA-199991	1.526005e-01	0.816	0	0
G1 Phase	R-HSA-69236	5.272970e-01	0.278	0	0
Cyclin D associated events in G1	R-HSA-69231	5.272970e-01	0.278	0	0
Negative regulation of FGFR3 signaling	R-HSA-5654732	6.539353e-01	0.184	1	1
Signaling by SCF-KIT	R-HSA-1433557	1.414145e-01	0.850	0	0
FGFR1 mutant receptor activation	R-HSA-1839124	1.475375e-01	0.831	0	0
CD209 (DC-SIGN) signaling	R-HSA-5621575	2.068878e-01	0.684	0	0
Protein-protein interactions at synapses	R-HSA-6794362	1.731413e-01	0.762	0	0
UCH proteinases	R-HSA-5689603	5.474416e-01	0.262	0	0
Developmental Biology	R-HSA-1266738	5.123316e-01	0.290	1	0
Interleukin-2 signaling	R-HSA-9020558	5.499809e-01	0.260	0	0
Clathrin-mediated endocytosis	R-HSA-8856828	6.326676e-01	0.199	0	0
PI5P Regulates TP53 Acetylation	R-HSA-6811555	3.875154e-01	0.412	0	0
InlB-mediated entry of Listeria monocytogenes into host cell	R-HSA-8875360	4.566211e-01	0.340	0	0
MAPK1/MAPK3 signaling	R-HSA-5684996	4.344161e-01	0.362	1	0
Activated NOTCH1 Transmits Signal to the Nucleus	R-HSA-2122948	6.071997e-01	0.217	0	0
Transcriptional Regulation by VENTX	R-HSA-8853884	3.008808e-01	0.522	0	0
RAF/MAP kinase cascade	R-HSA-5673001	4.385477e-01	0.358	1	1
Signaling by FLT3 fusion proteins	R-HSA-9703465	4.127174e-01	0.384	0	0
Gastrulation	R-HSA-9758941	4.424286e-01	0.354	0	0
DNA Repair	R-HSA-73894	4.640735e-01	0.333	0	0
Transcriptional activation of p53 responsive genes	R-HSA-69560	1.875733e-01	0.727	0	0
Transcriptional activation of cell cycle inhibitor p21	R-HSA-69895	1.875733e-01	0.727	0	0
Release of Hh-Np from the secreting cell	R-HSA-5362798	2.838155e-01	0.547	0	0
Postmitotic nuclear pore complex (NPC) reformation	R-HSA-9615933	1.338081e-01	0.874	0	0
Dopamine Neurotransmitter Release Cycle	R-HSA-212676	1.677922e-01	0.775	0	0
POLB-Dependent Long Patch Base Excision Repair	R-HSA-110362	3.164964e-01	0.500	0	0
SARS-CoV-1-mediated effects on programmed cell death	R-HSA-9692913	5.461834e-01	0.263	0	0
Deadenylation-dependent mRNA decay	R-HSA-429914	2.726909e-01	0.564	0	0
Formation of the anterior neural plate	R-HSA-9823739	4.566211e-01	0.340	0	0
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	R-HSA-3772470	5.872513e-01	0.231	0	0
S Phase	R-HSA-69242	6.020193e-01	0.220	0	0
Intracellular signaling by second messengers	R-HSA-9006925	3.853752e-01	0.414	1	0
MAP kinase activation	R-HSA-450294	2.048117e-01	0.689	1	0
Cellular responses to stress	R-HSA-2262752	5.402512e-01	0.267	1	0
Cargo trafficking to the periciliary membrane	R-HSA-5620920	5.914890e-01	0.228	0	0
Signaling by WNT	R-HSA-195721	6.358644e-01	0.197	0	0
RAF-independent MAPK1/3 activation	R-HSA-112409	5.031022e-01	0.298	1	1
MAPK family signaling cascades	R-HSA-5683057	2.222723e-01	0.653	1	0
Signaling by TGF-beta Receptor Complex in Cancer	R-HSA-3304351	3.319171e-01	0.479	0	0
Recycling pathway of L1	R-HSA-437239	1.944210e-01	0.711	0	0
Interleukin-17 signaling	R-HSA-448424	2.341701e-01	0.630	1	0
Myogenesis	R-HSA-525793	4.127174e-01	0.384	0	0
NoRC negatively regulates rRNA expression	R-HSA-427413	4.670637e-01	0.331	0	0
Synthesis of PIPs at the late endosome membrane	R-HSA-1660517	5.533348e-01	0.257	0	0
Mitochondrial unfolded protein response (UPRmt)	R-HSA-9841251	6.310434e-01	0.200	0	0
Sema4D induced cell migration and growth-cone collapse	R-HSA-416572	6.390279e-01	0.194	0	0
Intrinsic Pathway for Apoptosis	R-HSA-109606	2.281554e-01	0.642	1	0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	R-HSA-5649702	4.685992e-01	0.329	0	0
Killing mechanisms	R-HSA-9664420	4.899334e-01	0.310	0	0
WNT5:FZD7-mediated leishmania damping	R-HSA-9673324	4.899334e-01	0.310	0	0
TNF signaling	R-HSA-75893	2.281554e-01	0.642	0	0
Negative Regulation of CDH1 Gene Transcription	R-HSA-9764725	1.919788e-01	0.717	1	1
Spry regulation of FGF signaling	R-HSA-1295596	4.566211e-01	0.340	1	1
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes	R-HSA-9856532	6.117968e-01	0.213	0	0
Rab regulation of trafficking	R-HSA-9007101	4.597913e-01	0.337	0	0
Nervous system development	R-HSA-9675108	1.488044e-01	0.827	1	0
Sema4D in semaphorin signaling	R-HSA-400685	3.870431e-01	0.412	0	0
Regulation of TNFR1 signaling	R-HSA-5357905	4.175850e-01	0.379	0	0
Mitotic G2-G2/M phases	R-HSA-453274	3.935720e-01	0.405	0	0
Activation of BH3-only proteins	R-HSA-114452	2.006069e-01	0.698	0	0
G2/M Transition	R-HSA-69275	4.481902e-01	0.349	0	0
Semaphorin interactions	R-HSA-373755	5.895267e-01	0.229	0	0
Axon guidance	R-HSA-422475	3.141495e-01	0.503	1	0
SARS-CoV-2 targets PDZ proteins in cell-cell junction	R-HSA-9705677	1.875733e-01	0.727	0	0
Transport of connexins along the secretory pathway	R-HSA-190827	3.263161e-01	0.486	0	0
Defective Mismatch Repair Associated With MSH2	R-HSA-5632928	3.263161e-01	0.486	0	0
RUNX2 regulates chondrocyte maturation	R-HSA-8941284	2.354119e-01	0.628	0	0
TGFBR3 regulates activin signaling	R-HSA-9839406	4.094349e-01	0.388	0	0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	R-HSA-446343	4.094349e-01	0.388	0	0
Depolymerization of the Nuclear Lamina	R-HSA-4419969	1.893467e-01	0.723	0	0
Serotonin Neurotransmitter Release Cycle	R-HSA-181429	1.893467e-01	0.723	0	0
Negative regulation of FLT3	R-HSA-9706369	2.711569e-01	0.567	0	0
Signaling by AMER1 mutants	R-HSA-4839748	3.164964e-01	0.500	0	0
Loss of MECP2 binding ability to 5mC-DNA	R-HSA-9022538	4.823027e-01	0.317	0	0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	R-HSA-5368598	4.823027e-01	0.317	0	0
Signaling by LTK	R-HSA-9842663	3.521215e-01	0.453	0	0
Interleukin-23 signaling	R-HSA-9020933	4.247348e-01	0.372	0	0
Sodium/Proton exchangers	R-HSA-425986	4.247348e-01	0.372	0	0
Membrane binding and targetting of GAG proteins	R-HSA-174490	3.875154e-01	0.412	0	0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	R-HSA-9634638	3.356093e-01	0.474	1	1
Inactivation of CDC42 and RAC1	R-HSA-428543	4.685992e-01	0.329	0	0
AKT phosphorylates targets in the nucleus	R-HSA-198693	4.685992e-01	0.329	0	0
RUNX2 regulates genes involved in differentiation of myeloid cells	R-HSA-8941333	5.461834e-01	0.263	0	0
Collagen degradation	R-HSA-1442490	3.037844e-01	0.517	0	0
HIV Infection	R-HSA-162906	1.874006e-01	0.727	0	0
Regulation of MECP2 expression and activity	R-HSA-9022692	4.076449e-01	0.390	0	0
Interleukin-27 signaling	R-HSA-9020956	5.104008e-01	0.292	0	0
EGFR Transactivation by Gastrin	R-HSA-2179392	5.104008e-01	0.292	0	0
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	3.968349e-01	0.401	0	0
Disorders of Developmental Biology	R-HSA-9675151	5.222102e-01	0.282	0	0
Ionotropic activity of kainate receptors	R-HSA-451306	5.499809e-01	0.260	0	0
NTRK2 activates RAC1	R-HSA-9032759	6.021848e-01	0.220	0	0
Loss of Function of TGFBR1 in Cancer	R-HSA-3656534	6.021848e-01	0.220	0	0
Negative regulation of the PI3K/AKT network	R-HSA-199418	4.475940e-01	0.349	1	0
Regulation of FZD by ubiquitination	R-HSA-4641263	5.533348e-01	0.257	0	0
Budding and maturation of HIV virion	R-HSA-162588	5.367930e-01	0.270	0	0
Sema4D mediated inhibition of cell attachment and migration	R-HSA-416550	5.872513e-01	0.231	0	0
Synaptic adhesion-like molecules	R-HSA-8849932	5.832184e-01	0.234	0	0
Association of TriC/CCT with target proteins during biosynthesis	R-HSA-390471	6.051559e-01	0.218	0	0
Synthesis of PS	R-HSA-1483101	6.512785e-01	0.186	0	0
Sensory perception of salty taste	R-HSA-9730628	6.512785e-01	0.186	0	0
Synthesis of dolichyl-phosphate mannose	R-HSA-162699	6.512785e-01	0.186	0	0
Signaling by NOTCH2	R-HSA-1980145	6.266147e-01	0.203	0	0
PI3K Cascade	R-HSA-109704	6.405541e-01	0.193	0	0
Deubiquitination	R-HSA-5688426	3.417474e-01	0.466	0	0
Diseases of programmed cell death	R-HSA-9645723	5.116927e-01	0.291	0	0
Synthesis of PIPs at the plasma membrane	R-HSA-1660499	1.400063e-01	0.854	0	0
Signaling by FGFR in disease	R-HSA-1226099	2.888173e-01	0.539	0	0
Ca2+ pathway	R-HSA-4086398	3.805731e-01	0.420	0	0
G1/S Transition	R-HSA-69206	2.305856e-01	0.637	0	0
Signaling by FGFR4 in disease	R-HSA-5655291	4.224213e-01	0.374	0	0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	R-HSA-164938	5.533348e-01	0.257	0	0
Resolution of Abasic Sites (AP sites)	R-HSA-73933	4.449220e-01	0.352	0	0
Synthesis of PIPs at the Golgi membrane	R-HSA-1660514	4.127174e-01	0.384	0	0
Cytoprotection by HMOX1	R-HSA-9707564	3.160892e-01	0.500	0	0
Cell junction organization	R-HSA-446728	4.725021e-01	0.326	1	0
Uptake and function of anthrax toxins	R-HSA-5210891	1.675100e-01	0.776	0	0
The role of Nef in HIV-1 replication and disease pathogenesis	R-HSA-164952	5.303251e-01	0.275	0	0
FLT3 signaling in disease	R-HSA-9682385	4.986152e-01	0.302	0	0
Cyclin A/B1/B2 associated events during G2/M transition	R-HSA-69273	1.475375e-01	0.831	0	0
MDK and PTN in ALK signaling	R-HSA-9851151	5.461834e-01	0.263	0	0
TBC/RABGAPs	R-HSA-8854214	3.587296e-01	0.445	0	0
Ovarian tumor domain proteases	R-HSA-5689896	5.206572e-01	0.283	0	0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	R-HSA-6811558	5.351688e-01	0.272	1	1
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	3.300728e-01	0.481	0	0
Nef and signal transduction	R-HSA-164944	3.319171e-01	0.479	0	0
Synthesis And Processing Of GAG, GAGPOL Polyproteins	R-HSA-174495	4.224213e-01	0.374	0	0
Interleukin-21 signaling	R-HSA-9020958	4.685992e-01	0.329	0	0
Regulated proteolysis of p75NTR	R-HSA-193692	4.685992e-01	0.329	0	0
Activation of NOXA and translocation to mitochondria	R-HSA-111448	5.461834e-01	0.263	0	0
p38MAPK events	R-HSA-171007	4.566211e-01	0.340	0	0
Signalling to RAS	R-HSA-167044	4.467310e-01	0.350	0	0
Carnitine shuttle	R-HSA-200425	5.303251e-01	0.275	0	0
Pervasive developmental disorders	R-HSA-9005895	6.221793e-01	0.206	0	0
Loss of function of MECP2 in Rett syndrome	R-HSA-9005891	6.221793e-01	0.206	0	0
Disorders of Nervous System Development	R-HSA-9697154	6.221793e-01	0.206	0	0
Transcriptional regulation by RUNX2	R-HSA-8878166	3.057724e-01	0.515	1	0
Activation of NMDA receptors and postsynaptic events	R-HSA-442755	5.219879e-01	0.282	1	0
Transcriptional Regulation by E2F6	R-HSA-8953750	1.583075e-01	0.800	0	0
Post NMDA receptor activation events	R-HSA-438064	3.871761e-01	0.412	1	0
Caspase activation via Dependence Receptors in the absence of ligand	R-HSA-418889	4.685992e-01	0.329	0	0
Downstream signal transduction	R-HSA-186763	5.367930e-01	0.270	0	0
Maternal to zygotic transition (MZT)	R-HSA-9816359	3.519468e-01	0.454	0	0
Signaling by Hippo	R-HSA-2028269	1.675100e-01	0.776	0	0
Regulation of Expression and Function of Type II Classical Cadherins	R-HSA-9764260	2.575707e-01	0.589	0	0
Signal transduction by L1	R-HSA-445144	4.177918e-01	0.379	1	1
Regulation of NPAS4 gene expression	R-HSA-9768759	5.533348e-01	0.257	0	0
Formation of the dystrophin-glycoprotein complex (DGC)	R-HSA-9913351	5.367930e-01	0.270	0	0
Influenza Viral RNA Transcription and Replication	R-HSA-168273	5.934578e-01	0.227	0	0
Zygotic genome activation (ZGA)	R-HSA-9819196	1.322123e-01	0.879	0	0
Host Interactions of HIV factors	R-HSA-162909	3.637287e-01	0.439	0	0
Interleukin-3, Interleukin-5 and GM-CSF signaling	R-HSA-512988	2.180691e-01	0.661	0	0
PI Metabolism	R-HSA-1483255	3.237119e-01	0.490	0	0
Oligomerization of connexins into connexons	R-HSA-190704	3.263161e-01	0.486	0	0
Activation of RAC1 downstream of NMDARs	R-HSA-9619229	2.114021e-01	0.675	0	0
AKT phosphorylates targets in the cytosol	R-HSA-198323	3.521215e-01	0.453	0	0
Apoptotic execution phase	R-HSA-75153	1.804193e-01	0.744	0	0
Signaling by PDGFR in disease	R-HSA-9671555	2.848349e-01	0.545	0	0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors	R-HSA-8866904	4.247348e-01	0.372	0	0
CLEC7A (Dectin-1) induces NFAT activation	R-HSA-5607763	4.224213e-01	0.374	0	0
Sensory perception of sour taste	R-HSA-9729555	5.461834e-01	0.263	0	0
TLR3-mediated TICAM1-dependent programmed cell death	R-HSA-9013957	5.461834e-01	0.263	0	0
PI3K/AKT Signaling in Cancer	R-HSA-2219528	2.207224e-01	0.656	0	0
Acetylcholine Neurotransmitter Release Cycle	R-HSA-264642	4.467310e-01	0.350	0	0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	R-HSA-428359	5.104008e-01	0.292	0	0
Norepinephrine Neurotransmitter Release Cycle	R-HSA-181430	5.567920e-01	0.254	0	0
Signalling to p38 via RIT and RIN	R-HSA-187706	6.512785e-01	0.186	0	0
Pexophagy	R-HSA-9664873	5.104008e-01	0.292	0	0
Nonhomologous End-Joining (NHEJ)	R-HSA-5693571	4.567131e-01	0.340	0	0
MHC class II antigen presentation	R-HSA-2132295	4.411751e-01	0.355	0	0
Synthesis of PIPs at the early endosome membrane	R-HSA-1660516	5.824351e-01	0.235	0	0
Caspase-mediated cleavage of cytoskeletal proteins	R-HSA-264870	2.114021e-01	0.675	0	0
Transcriptional Regulation by MECP2	R-HSA-8986944	4.451728e-01	0.351	0	0
SARS-CoV-2 activates/modulates innate and adaptive immune responses	R-HSA-9705671	3.644927e-01	0.438	0	0
Signaling by NTRK2 (TRKB)	R-HSA-9006115	6.310434e-01	0.200	0	0
Regulation of CDH11 gene transcription	R-HSA-9762293	2.114021e-01	0.675	0	0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	R-HSA-9735871	2.426596e-01	0.615	0	0
Histamine receptors	R-HSA-390650	4.823027e-01	0.317	0	0
Collagen chain trimerization	R-HSA-8948216	2.277889e-01	0.642	0	0
Sensory processing of sound by inner hair cells of the cochlea	R-HSA-9662360	3.035915e-01	0.518	0	0
Regulation of CDH11 Expression and Function	R-HSA-9759475	4.883588e-01	0.311	0	0
PECAM1 interactions	R-HSA-210990	5.499809e-01	0.260	0	0
Tie2 Signaling	R-HSA-210993	5.832184e-01	0.234	0	0
Constitutive Signaling by AKT1 E17K in Cancer	R-HSA-5674400	3.356093e-01	0.474	0	0
Signaling by PDGF	R-HSA-186797	5.727448e-01	0.242	0	0
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	R-HSA-210746	3.319171e-01	0.479	0	0
Displacement of DNA glycosylase by APEX1	R-HSA-110357	3.790549e-01	0.421	0	0
The NLRP1 inflammasome	R-HSA-844455	4.823027e-01	0.317	0	0
Fibronectin matrix formation	R-HSA-1566977	3.001858e-01	0.523	0	0
Downregulation of ERBB2:ERBB3 signaling	R-HSA-1358803	3.521215e-01	0.453	0	0
Regulation of gene expression in beta cells	R-HSA-210745	3.155193e-01	0.501	0	0
Activation of the TFAP2 (AP-2) family of transcription factors	R-HSA-8866907	4.685992e-01	0.329	0	0
Dopamine receptors	R-HSA-390651	5.461834e-01	0.263	0	0
FLT3 signaling through SRC family kinases	R-HSA-9706374	5.461834e-01	0.263	0	0
Negative regulation of NMDA receptor-mediated neuronal transmission	R-HSA-9617324	4.752052e-01	0.323	0	0
Glutamate Neurotransmitter Release Cycle	R-HSA-210500	6.071997e-01	0.217	0	0
Relaxin receptors	R-HSA-444821	6.512785e-01	0.186	0	0
Sensory processing of sound	R-HSA-9659379	3.616595e-01	0.442	0	0
Netrin-1 signaling	R-HSA-373752	3.783051e-01	0.422	0	0
Apoptotic cleavage of cell adhesion proteins	R-HSA-351906	4.247348e-01	0.372	0	0
Gene Silencing by RNA	R-HSA-211000	5.001200e-01	0.301	0	0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	R-HSA-2660826	6.512785e-01	0.186	0	0
Aryl hydrocarbon receptor signalling	R-HSA-8937144	6.512785e-01	0.186	0	0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	R-HSA-2660825	6.512785e-01	0.186	0	0
Interleukin-7 signaling	R-HSA-1266695	5.824351e-01	0.235	0	0
Antiviral mechanism by IFN-stimulated genes	R-HSA-1169410	2.041374e-01	0.690	1	0
Growth hormone receptor signaling	R-HSA-982772	3.356093e-01	0.474	1	1
tRNA processing	R-HSA-72306	5.979563e-01	0.223	0	0
Glycolysis	R-HSA-70171	3.922410e-01	0.406	0	0
PTK6 Regulates Proteins Involved in RNA Processing	R-HSA-8849468	6.021848e-01	0.220	0	0
RMTs methylate histone arginines	R-HSA-3214858	5.272970e-01	0.278	0	0
XBP1(S) activates chaperone genes	R-HSA-381038	5.954827e-01	0.225	0	0
Sensory processing of sound by outer hair cells of the cochlea	R-HSA-9662361	3.372588e-01	0.472	0	0
Nectin/Necl trans heterodimerization	R-HSA-420597	6.021848e-01	0.220	0	0
BMAL1:CLOCK,NPAS2 activates circadian expression	R-HSA-1368108	2.978595e-01	0.526	0	0
Glucose metabolism	R-HSA-70326	6.513572e-01	0.186	0	0
Signaling by FGFR4	R-HSA-5654743	6.616994e-01	0.179	1	0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	R-HSA-450321	6.648887e-01	0.177	0	0
TNFR1-induced proapoptotic signaling	R-HSA-5357786	6.648887e-01	0.177	0	0
Apoptosis	R-HSA-109581	6.652245e-01	0.177	1	0
RNA Polymerase I Promoter Clearance	R-HSA-73854	6.664156e-01	0.176	1	0
GPVI-mediated activation cascade	R-HSA-114604	6.673515e-01	0.176	0	0
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	6.750593e-01	0.171	1	0
Signaling by Erythropoietin	R-HSA-9006335	6.758544e-01	0.170	0	0
mRNA Capping	R-HSA-72086	6.758544e-01	0.170	0	0
Negative regulation of FGFR4 signaling	R-HSA-5654733	6.758544e-01	0.170	1	1
Platelet calcium homeostasis	R-HSA-418360	6.758544e-01	0.170	0	0
MyD88 cascade initiated on plasma membrane	R-HSA-975871	6.758563e-01	0.170	1	0
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	6.758563e-01	0.170	1	0
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	6.758563e-01	0.170	1	0
IRE1alpha activates chaperones	R-HSA-381070	6.769591e-01	0.169	0	0
MAPK6/MAPK4 signaling	R-HSA-5687128	6.784418e-01	0.168	0	0
Physiological factors	R-HSA-5578768	6.850831e-01	0.164	0	0
MAP3K8 (TPL2)-dependent MAPK1/3 activation	R-HSA-5684264	6.850831e-01	0.164	0	0
IRS-related events triggered by IGF1R	R-HSA-2428928	6.863653e-01	0.163	0	0
RNA Polymerase III Transcription Initiation From Type 2 Promoter	R-HSA-76066	6.893722e-01	0.162	0	0
Listeria monocytogenes entry into host cells	R-HSA-8876384	6.893722e-01	0.162	0	0
Assembly Of The HIV Virion	R-HSA-175474	6.893722e-01	0.162	0	0
EPH-Ephrin signaling	R-HSA-2682334	6.895713e-01	0.161	0	0
B-WICH complex positively regulates rRNA expression	R-HSA-5250924	6.908404e-01	0.161	0	0
Smooth Muscle Contraction	R-HSA-445355	6.908404e-01	0.161	0	0
RAB GEFs exchange GTP for GDP on RABs	R-HSA-8876198	6.915356e-01	0.160	0	0
RNA Polymerase I Transcription	R-HSA-73864	6.940347e-01	0.159	1	0
Signaling by LTK in cancer	R-HSA-9842640	6.943161e-01	0.158	1	1
Activation of NIMA Kinases NEK9, NEK6, NEK7	R-HSA-2980767	6.943161e-01	0.158	0	0
STAT5 Activation	R-HSA-9645135	6.943161e-01	0.158	0	0
Erythropoietin activates STAT5	R-HSA-9027283	6.943161e-01	0.158	0	0
Autointegration results in viral DNA circles	R-HSA-177539	6.943161e-01	0.158	0	0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD	R-HSA-9865125	6.943161e-01	0.158	0	0
H139Hfs13* PPM1K causes a mild variant of MSUD	R-HSA-9912529	6.943161e-01	0.158	0	0
E2F-enabled inhibition of pre-replication complex formation	R-HSA-113507	6.943161e-01	0.158	0	0
Branched-chain ketoacid dehydrogenase kinase deficiency	R-HSA-9912481	6.943161e-01	0.158	0	0
Defective CHST14 causes EDS, musculocontractural type	R-HSA-3595174	6.943161e-01	0.158	0	0
RAS signaling downstream of NF1 loss-of-function variants	R-HSA-6802953	6.943161e-01	0.158	0	0
Intracellular metabolism of fatty acids regulates insulin secretion	R-HSA-434313	6.943161e-01	0.158	0	0
Neurofascin interactions	R-HSA-447043	6.943161e-01	0.158	0	0
Integration of viral DNA into host genomic DNA	R-HSA-175567	6.943161e-01	0.158	0	0
NADPH regeneration	R-HSA-389542	6.943161e-01	0.158	0	0
HDL clearance	R-HSA-8964011	6.943161e-01	0.158	0	0
CREB3 factors activate genes	R-HSA-8874211	6.943161e-01	0.158	0	0
Defective factor VIII causes hemophilia A	R-HSA-9662001	6.943161e-01	0.158	0	0
Regulation of Homotypic Cell-Cell Adhesion	R-HSA-9759476	6.944412e-01	0.158	1	0
DAP12 signaling	R-HSA-2424491	6.967890e-01	0.157	0	0
Signaling by FGFR3	R-HSA-5654741	6.968384e-01	0.157	1	0
Ub-specific processing proteases	R-HSA-5689880	7.029470e-01	0.153	0	0
Regulation of CDH1 Expression and Function	R-HSA-9764265	7.029470e-01	0.153	1	0
Regulation of Expression and Function of Type I Classical Cadherins	R-HSA-9764274	7.029470e-01	0.153	1	0
SARS-CoV-2-host interactions	R-HSA-9705683	7.038843e-01	0.152	0	0
Translation initiation complex formation	R-HSA-72649	7.065508e-01	0.151	0	0
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	7.080739e-01	0.150	1	0
Cell-Cell communication	R-HSA-1500931	7.091683e-01	0.149	1	0
NOTCH3 Activation and Transmission of Signal to the Nucleus	R-HSA-9013507	7.124858e-01	0.147	0	0
FGFR2 alternative splicing	R-HSA-6803529	7.124858e-01	0.147	0	0
Developmental Lineage of Mammary Stem Cells	R-HSA-9938206	7.124858e-01	0.147	0	0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	R-HSA-9670439	7.124858e-01	0.147	0	0
RNA Polymerase III Transcription Initiation From Type 1 Promoter	R-HSA-76061	7.124858e-01	0.147	0	0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	R-HSA-6803205	7.124858e-01	0.147	0	0
Signaling by KIT in disease	R-HSA-9669938	7.124858e-01	0.147	0	0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	R-HSA-8948700	7.131708e-01	0.147	0	0
SHC1 events in EGFR signaling	R-HSA-180336	7.131708e-01	0.147	0	0
Sema3A PAK dependent Axon repulsion	R-HSA-399954	7.131708e-01	0.147	0	0
Signaling by PDGFRA extracellular domain mutants	R-HSA-9673770	7.131708e-01	0.147	0	0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	R-HSA-9673767	7.131708e-01	0.147	0	0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	R-HSA-450385	7.131708e-01	0.147	0	0
Biotin transport and metabolism	R-HSA-196780	7.131708e-01	0.147	0	0
Cellular responses to stimuli	R-HSA-8953897	7.188152e-01	0.143	1	0
COPI-independent Golgi-to-ER retrograde traffic	R-HSA-6811436	7.217218e-01	0.142	0	0
HDACs deacetylate histones	R-HSA-3214815	7.217218e-01	0.142	0	0
Formation of HIV-1 elongation complex containing HIV-1 Tat	R-HSA-167200	7.227575e-01	0.141	0	0
Regulation of TP53 Expression and Degradation	R-HSA-6806003	7.227575e-01	0.141	0	0
Developmental Lineages of the Mammary Gland	R-HSA-9924644	7.244549e-01	0.140	0	0
Reproduction	R-HSA-1474165	7.258489e-01	0.139	0	0
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	7.294495e-01	0.137	0	0
Retrograde transport at the Trans-Golgi-Network	R-HSA-6811440	7.294495e-01	0.137	0	0
IGF1R signaling cascade	R-HSA-2428924	7.297299e-01	0.137	0	0
TRIF (TICAM1)-mediated TLR4 signaling	R-HSA-937061	7.314108e-01	0.136	1	0
MyD88-independent TLR4 cascade	R-HSA-166166	7.314108e-01	0.136	1	0
MET activates PI3K/AKT signaling	R-HSA-8851907	7.320444e-01	0.135	0	0
RUNX3 Regulates Immune Response and Cell Migration	R-HSA-8949275	7.320444e-01	0.135	0	0
Pre-NOTCH Processing in the Endoplasmic Reticulum	R-HSA-1912399	7.320444e-01	0.135	0	0
SLBP independent Processing of Histone Pre-mRNAs	R-HSA-111367	7.320444e-01	0.135	0	0
Microbial modulation of RIPK1-mediated regulated necrosis	R-HSA-9686347	7.320444e-01	0.135	0	0
Activated NTRK3 signals through PI3K	R-HSA-9603381	7.320444e-01	0.135	0	0
Synthesis of PIPs in the nucleus	R-HSA-8847453	7.320444e-01	0.135	0	0
TRIF-mediated programmed cell death	R-HSA-2562578	7.320444e-01	0.135	0	0
VLDL clearance	R-HSA-8964046	7.320444e-01	0.135	0	0
Defective HLCS causes multiple carboxylase deficiency	R-HSA-3371599	7.320444e-01	0.135	0	0
Cation-coupled Chloride cotransporters	R-HSA-426117	7.320444e-01	0.135	0	0
CHL1 interactions	R-HSA-447041	7.320444e-01	0.135	0	0
Nef Mediated CD4 Down-regulation	R-HSA-167590	7.320444e-01	0.135	0	0
Activated NTRK2 signals through CDK5	R-HSA-9032845	7.320444e-01	0.135	0	0
Maturation of replicase proteins	R-HSA-9694301	7.320444e-01	0.135	0	0
Regulation of PTEN mRNA translation	R-HSA-8943723	7.342481e-01	0.134	0	0
Termination of O-glycan biosynthesis	R-HSA-977068	7.342481e-01	0.134	0	0
Recognition and association of DNA glycosylase with site containing an affected purine	R-HSA-110330	7.356979e-01	0.133	0	0
Ribosomal scanning and start codon recognition	R-HSA-72702	7.363491e-01	0.133	0	0
Translocation of SLC2A4 (GLUT4) to the plasma membrane	R-HSA-1445148	7.374477e-01	0.132	0	0
GRB2:SOS provides linkage to MAPK signaling for Integrins	R-HSA-354194	7.391247e-01	0.131	0	0
Aberrant regulation of mitotic exit in cancer due to RB1 defects	R-HSA-9687136	7.391247e-01	0.131	0	0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	R-HSA-399955	7.391247e-01	0.131	0	0
HIV Transcription Elongation	R-HSA-167169	7.396795e-01	0.131	0	0
Tat-mediated elongation of the HIV-1 transcript	R-HSA-167246	7.396795e-01	0.131	0	0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	R-HSA-427389	7.396795e-01	0.131	0	0
Cellular response to hypoxia	R-HSA-1234174	7.432409e-01	0.129	0	0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	7.432409e-01	0.129	0	0
mRNA Splicing - Major Pathway	R-HSA-72163	7.442197e-01	0.128	0	0
Adherens junctions interactions	R-HSA-418990	7.500525e-01	0.125	1	0
ER to Golgi Anterograde Transport	R-HSA-199977	7.507263e-01	0.125	0	0
Integrin signaling	R-HSA-354192	7.536858e-01	0.123	0	0
Regulation of necroptotic cell death	R-HSA-5675482	7.536858e-01	0.123	0	0
Negative regulation of FGFR1 signaling	R-HSA-5654726	7.536858e-01	0.123	1	1
DNA Damage Bypass	R-HSA-73893	7.595066e-01	0.119	0	0
HCMV Early Events	R-HSA-9609690	7.597025e-01	0.119	0	0
tRNA modification in the mitochondrion	R-HSA-6787450	7.630436e-01	0.117	0	0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	R-HSA-400511	7.630436e-01	0.117	0	0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	R-HSA-72662	7.639691e-01	0.117	0	0
RSK activation	R-HSA-444257	7.651180e-01	0.116	1	1
EGFR interacts with phospholipase C-gamma	R-HSA-212718	7.651180e-01	0.116	0	0
Activation of RAS in B cells	R-HSA-1169092	7.651180e-01	0.116	0	0
Activated NTRK2 signals through PI3K	R-HSA-9028335	7.651180e-01	0.116	0	0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	R-HSA-8939242	7.651180e-01	0.116	0	0
Nef mediated downregulation of MHC class I complex cell surface expression	R-HSA-164940	7.651180e-01	0.116	0	0
Axonal growth inhibition (RHOA activation)	R-HSA-193634	7.651180e-01	0.116	0	0
Interleukin-9 signaling	R-HSA-8985947	7.651180e-01	0.116	0	0
TGFBR3 PTM regulation	R-HSA-9839383	7.651180e-01	0.116	0	0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	R-HSA-8849469	7.651180e-01	0.116	0	0
Activated NTRK2 signals through FYN	R-HSA-9032500	7.651180e-01	0.116	0	0
mRNA Splicing	R-HSA-72172	7.662208e-01	0.116	0	0
Striated Muscle Contraction	R-HSA-390522	7.707148e-01	0.113	0	0
DNA Damage Recognition in GG-NER	R-HSA-5696394	7.707148e-01	0.113	0	0
Miscellaneous transport and binding events	R-HSA-5223345	7.707148e-01	0.113	0	0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	R-HSA-9615017	7.712194e-01	0.113	0	0
Assembly and cell surface presentation of NMDA receptors	R-HSA-9609736	7.712194e-01	0.113	0	0
Vesicle-mediated transport	R-HSA-5653656	7.717176e-01	0.113	0	0
Acyl chain remodelling of PS	R-HSA-1482801	7.738404e-01	0.111	0	0
Extension of Telomeres	R-HSA-180786	7.769650e-01	0.110	0	0
Collagen biosynthesis and modifying enzymes	R-HSA-1650814	7.809216e-01	0.107	0	0
p130Cas linkage to MAPK signaling for integrins	R-HSA-372708	7.850344e-01	0.105	0	0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	R-HSA-176407	7.850344e-01	0.105	0	0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	R-HSA-5358606	7.850344e-01	0.105	0	0
Elevation of cytosolic Ca2+ levels	R-HSA-139853	7.850344e-01	0.105	0	0
Modulation of host responses by IFN-stimulated genes	R-HSA-9909505	7.850344e-01	0.105	0	0
Specification of primordial germ cells	R-HSA-9827857	7.850344e-01	0.105	0	0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells	R-HSA-9927418	7.858560e-01	0.105	0	0
Negative regulation of FGFR2 signaling	R-HSA-5654727	7.868049e-01	0.104	1	1
NOD1/2 Signaling Pathway	R-HSA-168638	7.868049e-01	0.104	0	0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	R-HSA-110328	7.868049e-01	0.104	0	0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	R-HSA-1234176	7.870324e-01	0.104	0	0
HSF1-dependent transactivation	R-HSA-3371571	7.870324e-01	0.104	0	0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	R-HSA-110373	7.917488e-01	0.101	0	0
Attachment of bacteria to epithelial cells	R-HSA-9638630	7.917488e-01	0.101	0	0
MECP2 regulates neuronal receptors and channels	R-HSA-9022699	7.917488e-01	0.101	0	0
AMPK inhibits chREBP transcriptional activation activity	R-HSA-163680	7.941111e-01	0.100	0	0
Unwinding of DNA	R-HSA-176974	7.941111e-01	0.100	0	0
IRAK2 mediated activation of TAK1 complex	R-HSA-937042	7.941111e-01	0.100	0	0
p75NTR regulates axonogenesis	R-HSA-193697	7.941111e-01	0.100	0	0
Regulation of signaling by NODAL	R-HSA-1433617	7.941111e-01	0.100	0	0
MAPK1 (ERK2) activation	R-HSA-112411	7.941111e-01	0.100	0	0
WNT mediated activation of DVL	R-HSA-201688	7.941111e-01	0.100	0	0
Regulation of NPAS4 gene transcription	R-HSA-9768777	7.941111e-01	0.100	0	0
NOTCH4 Activation and Transmission of Signal to the Nucleus	R-HSA-9013700	7.941111e-01	0.100	0	0
Lipophagy	R-HSA-9613354	7.941111e-01	0.100	0	0
Defects in biotin (Btn) metabolism	R-HSA-3323169	7.941111e-01	0.100	0	0
Cellular response to mitochondrial stress	R-HSA-9840373	7.941111e-01	0.100	0	0
Developmental Cell Lineages of the Integumentary System	R-HSA-9734779	7.941894e-01	0.100	0	0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	7.941894e-01	0.100	1	0
Uptake and actions of bacterial toxins	R-HSA-5339562	7.998644e-01	0.097	0	0
PERK regulates gene expression	R-HSA-381042	8.019800e-01	0.096	0	0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	R-HSA-9860927	8.019800e-01	0.096	0	0
MyD88 dependent cascade initiated on endosome	R-HSA-975155	8.032025e-01	0.095	1	0
COPII-mediated vesicle transport	R-HSA-204005	8.036886e-01	0.095	0	0
Cyclin E associated events during G1/S transition	R-HSA-69202	8.036886e-01	0.095	0	0
GAB1 signalosome	R-HSA-180292	8.052085e-01	0.094	0	0
RNA Polymerase III Transcription Termination	R-HSA-73980	8.052085e-01	0.094	0	0
Apoptotic factor-mediated response	R-HSA-111471	8.052085e-01	0.094	1	0
Chaperone Mediated Autophagy	R-HSA-9613829	8.052085e-01	0.094	0	0
Vitamin D (calciferol) metabolism	R-HSA-196791	8.052085e-01	0.094	0	0
Packaging Of Telomere Ends	R-HSA-171306	8.084597e-01	0.092	0	0
Signaling by FGFR3 in disease	R-HSA-5655332	8.084597e-01	0.092	0	0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	R-HSA-193807	8.084597e-01	0.092	0	0
Insulin processing	R-HSA-264876	8.084597e-01	0.092	0	0
Maturation of hRSV A proteins	R-HSA-9828806	8.084597e-01	0.092	0	0
Golgi Associated Vesicle Biogenesis	R-HSA-432722	8.120898e-01	0.090	0	0
NCAM signaling for neurite out-growth	R-HSA-375165	8.127574e-01	0.090	1	1
Unfolded Protein Response (UPR)	R-HSA-381119	8.130558e-01	0.090	0	0
Influenza Infection	R-HSA-168255	8.145783e-01	0.089	0	0
Regulation of TP53 Degradation	R-HSA-6804757	8.162670e-01	0.088	0	0
Signaling by FGFR2	R-HSA-5654738	8.166248e-01	0.088	1	0
Selective autophagy	R-HSA-9663891	8.192793e-01	0.087	0	0
Erythropoietin activates Phospholipase C gamma (PLCG)	R-HSA-9027277	8.195269e-01	0.086	0	0
Apoptosis induced DNA fragmentation	R-HSA-140342	8.195269e-01	0.086	0	0
TICAM1,TRAF6-dependent induction of TAK1 complex	R-HSA-9014325	8.195269e-01	0.086	0	0
Josephin domain DUBs	R-HSA-5689877	8.195269e-01	0.086	0	0
Defective RIPK1-mediated regulated necrosis	R-HSA-9693928	8.195269e-01	0.086	0	0
2-LTR circle formation	R-HSA-164843	8.195269e-01	0.086	0	0
Arachidonate production from DAG	R-HSA-426048	8.195269e-01	0.086	0	0
Cross-presentation of particulate exogenous antigens (phagosomes)	R-HSA-1236973	8.195269e-01	0.086	0	0
Receptor Mediated Mitophagy	R-HSA-8934903	8.195269e-01	0.086	0	0
MECP2 regulates transcription of neuronal ligands	R-HSA-9022702	8.195269e-01	0.086	0	0
Sperm Motility And Taxes	R-HSA-1300642	8.195269e-01	0.086	0	0
Pre-NOTCH Processing in Golgi	R-HSA-1912420	8.236792e-01	0.084	0	0
PI-3K cascade:FGFR3	R-HSA-5654710	8.236792e-01	0.084	0	0
APC/C:Cdc20 mediated degradation of Cyclin B	R-HSA-174048	8.236792e-01	0.084	0	0
Signaling by FGFR2 IIIa TM	R-HSA-8851708	8.236792e-01	0.084	0	0
Specification of the neural plate border	R-HSA-9834899	8.236792e-01	0.084	0	0
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	8.236792e-01	0.084	1	1
The NLRP3 inflammasome	R-HSA-844456	8.236792e-01	0.084	0	0
Diseases of hemostasis	R-HSA-9671793	8.236792e-01	0.084	0	0
Telomere Extension By Telomerase	R-HSA-171319	8.240236e-01	0.084	0	0
Activation of kainate receptors upon glutamate binding	R-HSA-451326	8.240236e-01	0.084	0	0
Inflammasomes	R-HSA-622312	8.240236e-01	0.084	0	0
Cyclin A:Cdk2-associated events at S phase entry	R-HSA-69656	8.246202e-01	0.084	0	0
Response of EIF2AK4 (GCN2) to amino acid deficiency	R-HSA-9633012	8.253046e-01	0.083	0	0
Platelet Aggregation (Plug Formation)	R-HSA-76009	8.254053e-01	0.083	0	0
Signaling by Interleukins	R-HSA-449147	8.275595e-01	0.082	1	0
Programmed Cell Death	R-HSA-5357801	8.278467e-01	0.082	1	0
HCMV Late Events	R-HSA-9610379	8.286785e-01	0.082	0	0
Cleavage of the damaged purine	R-HSA-110331	8.296954e-01	0.081	0	0
NCAM1 interactions	R-HSA-419037	8.296954e-01	0.081	0	0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	8.340381e-01	0.079	0	0
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	8.363853e-01	0.078	1	0
Formation of the ternary complex, and subsequently, the 43S complex	R-HSA-72695	8.371964e-01	0.077	0	0
Base Excision Repair	R-HSA-73884	8.372083e-01	0.077	0	0
Downstream signaling of activated FGFR3	R-HSA-5654708	8.384932e-01	0.077	0	0
Termination of translesion DNA synthesis	R-HSA-5656169	8.384932e-01	0.077	0	0
Endosomal Sorting Complex Required For Transport (ESCRT)	R-HSA-917729	8.384932e-01	0.077	0	0
Regulation of PD-L1(CD274) translation	R-HSA-9909620	8.405596e-01	0.075	0	0
PI-3K cascade:FGFR4	R-HSA-5654720	8.405596e-01	0.075	0	0
Co-inhibition by CTLA4	R-HSA-389513	8.405596e-01	0.075	0	0
Creatine metabolism	R-HSA-71288	8.405596e-01	0.075	0	0
Protein hydroxylation	R-HSA-9629569	8.405596e-01	0.075	0	0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	R-HSA-933543	8.418065e-01	0.075	0	0
CD163 mediating an anti-inflammatory response	R-HSA-9662834	8.418065e-01	0.075	0	0
Regulation of localization of FOXO transcription factors	R-HSA-9614399	8.418065e-01	0.075	0	0
Activated NTRK3 signals through RAS	R-HSA-9034864	8.418065e-01	0.075	0	0
Regulation of gene expression in early pancreatic precursor cells	R-HSA-210747	8.418065e-01	0.075	0	0
Synthesis of PI	R-HSA-1483226	8.418065e-01	0.075	0	0
Bicarbonate transporters	R-HSA-425381	8.418065e-01	0.075	0	0
Transport of RCbl within the body	R-HSA-9758890	8.418065e-01	0.075	0	0
Alpha-protein kinase 1 signaling pathway	R-HSA-9645460	8.418065e-01	0.075	0	0
Inorganic anion exchange by SLC26 transporters	R-HSA-427601	8.418065e-01	0.075	0	0
Suppression of apoptosis	R-HSA-9635465	8.418065e-01	0.075	1	1
RIPK1-mediated regulated necrosis	R-HSA-5213460	8.422968e-01	0.075	0	0
Depurination	R-HSA-73927	8.422968e-01	0.075	0	0
Gap-filling DNA repair synthesis and ligation in TC-NER	R-HSA-6782210	8.452601e-01	0.073	0	0
Signaling by FGFR1	R-HSA-5654736	8.452601e-01	0.073	1	0
Nuclear events mediated by NFE2L2	R-HSA-9759194	8.465656e-01	0.072	0	0
Aberrant regulation of mitotic cell cycle due to RB1 defects	R-HSA-9687139	8.519227e-01	0.070	0	0
Downstream signaling of activated FGFR4	R-HSA-5654716	8.519227e-01	0.070	0	0
Cell-cell junction organization	R-HSA-421270	8.524184e-01	0.069	1	0
Non-integrin membrane-ECM interactions	R-HSA-3000171	8.527140e-01	0.069	0	0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	R-HSA-9725554	8.541040e-01	0.068	0	0
Early Phase of HIV Life Cycle	R-HSA-162594	8.559608e-01	0.068	0	0
Co-stimulation by CD28	R-HSA-389356	8.588181e-01	0.066	0	0
ATF6 (ATF6-alpha) activates chaperone genes	R-HSA-381183	8.613368e-01	0.065	0	0
Condensation of Prometaphase Chromosomes	R-HSA-2514853	8.613368e-01	0.065	0	0
Integration of provirus	R-HSA-162592	8.613368e-01	0.065	0	0
Plasmalogen biosynthesis	R-HSA-75896	8.613368e-01	0.065	0	0
NF-kB is activated and signals survival	R-HSA-209560	8.613368e-01	0.065	0	0
Activated NTRK2 signals through RAS	R-HSA-9026519	8.613368e-01	0.065	0	0
ERKs are inactivated	R-HSA-202670	8.613368e-01	0.065	1	1
APOBEC3G mediated resistance to HIV-1 infection	R-HSA-180689	8.613368e-01	0.065	0	0
Synthesis of diphthamide-EEF2	R-HSA-5358493	8.613368e-01	0.065	0	0
DS-GAG biosynthesis	R-HSA-2022923	8.613368e-01	0.065	0	0
Metabolism of RNA	R-HSA-8953854	8.614124e-01	0.065	0	0
Kidney development	R-HSA-9830369	8.623059e-01	0.064	0	0
Stimuli-sensing channels	R-HSA-2672351	8.636306e-01	0.064	0	0
Trafficking of AMPA receptors	R-HSA-399719	8.643671e-01	0.063	0	0
Cargo concentration in the ER	R-HSA-5694530	8.643671e-01	0.063	0	0
Evasion by RSV of host interferon responses	R-HSA-9833109	8.643671e-01	0.063	0	0
Generation of second messenger molecules	R-HSA-202433	8.651511e-01	0.063	0	0
FRS-mediated FGFR3 signaling	R-HSA-5654706	8.699907e-01	0.060	0	0
Gap-filling DNA repair synthesis and ligation in GG-NER	R-HSA-5696397	8.699907e-01	0.060	0	0
Signaling by NTRK3 (TRKC)	R-HSA-9034015	8.699907e-01	0.060	0	0
Regulation of PD-L1(CD274) expression	R-HSA-9909648	8.738356e-01	0.059	0	0
Autophagy	R-HSA-9612973	8.747559e-01	0.058	0	0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	8.754725e-01	0.058	0	0
Signaling by FGFR2 in disease	R-HSA-5655253	8.779822e-01	0.057	0	0
Azathioprine ADME	R-HSA-9748787	8.779822e-01	0.057	0	0
IRAK1 recruits IKK complex	R-HSA-937039	8.784570e-01	0.056	0	0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	R-HSA-975144	8.784570e-01	0.056	0	0
Maple Syrup Urine Disease	R-HSA-9865114	8.784570e-01	0.056	0	0
Regulation of IFNG signaling	R-HSA-877312	8.784570e-01	0.056	0	0
Serotonin clearance from the synaptic cleft	R-HSA-380615	8.784570e-01	0.056	0	0
SHC-related events triggered by IGF1R	R-HSA-2428933	8.784570e-01	0.056	0	0
VLDLR internalisation and degradation	R-HSA-8866427	8.784570e-01	0.056	0	0
Signaling by NOTCH1 HD Domain Mutants in Cancer	R-HSA-2691230	8.784570e-01	0.056	0	0
Constitutive Signaling by NOTCH1 HD Domain Mutants	R-HSA-2691232	8.784570e-01	0.056	0	0
OAS antiviral response	R-HSA-8983711	8.784570e-01	0.056	0	0
PI-3K cascade:FGFR1	R-HSA-5654689	8.827530e-01	0.054	0	0
FRS-mediated FGFR4 signaling	R-HSA-5654712	8.827530e-01	0.054	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9694676	8.827530e-01	0.054	0	0
Developmental Lineage of Pancreatic Acinar Cells	R-HSA-9925561	8.844271e-01	0.053	0	0
Intra-Golgi traffic	R-HSA-6811438	8.851029e-01	0.053	0	0
Regulation of endogenous retroelements by KRAB-ZFP proteins	R-HSA-9843940	8.865076e-01	0.052	0	0
Fatty acyl-CoA biosynthesis	R-HSA-75105	8.865076e-01	0.052	0	0
G-protein beta:gamma signalling	R-HSA-397795	8.865193e-01	0.052	0	0
Glutamate binding, activation of AMPA receptors and synaptic plasticity	R-HSA-399721	8.865193e-01	0.052	0	0
Recycling of bile acids and salts	R-HSA-159418	8.865193e-01	0.052	0	0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	R-HSA-166058	8.897567e-01	0.051	1	0
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	8.897567e-01	0.051	1	0
PKR-mediated signaling	R-HSA-9833482	8.914052e-01	0.050	0	0
ATF6 (ATF6-alpha) activates chaperones	R-HSA-381033	8.934642e-01	0.049	0	0
Adenylate cyclase activating pathway	R-HSA-170660	8.934642e-01	0.049	0	0
Platelet Adhesion to exposed collagen	R-HSA-75892	8.934642e-01	0.049	0	0
Acyl chain remodeling of DAG and TAG	R-HSA-1482883	8.934642e-01	0.049	0	0
Processing of SMDT1	R-HSA-8949664	8.934642e-01	0.049	0	0
Maturation of nucleoprotein	R-HSA-9683610	8.934642e-01	0.049	0	0
Replication of the SARS-CoV-1 genome	R-HSA-9682706	8.934642e-01	0.049	0	0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	R-HSA-381676	8.940772e-01	0.049	0	0
Cleavage of the damaged pyrimidine	R-HSA-110329	8.940772e-01	0.049	0	0
Depyrimidination	R-HSA-73928	8.940772e-01	0.049	0	0
Interleukin-20 family signaling	R-HSA-8854691	8.943467e-01	0.048	0	0
Formation of the ureteric bud	R-HSA-9830674	8.943467e-01	0.048	0	0
RNA Polymerase I Promoter Escape	R-HSA-73772	8.948838e-01	0.048	0	0
RSV-host interactions	R-HSA-9833110	8.949987e-01	0.048	0	0
Interleukin-1 family signaling	R-HSA-446652	8.986940e-01	0.046	0	0
trans-Golgi Network Vesicle Budding	R-HSA-199992	9.005761e-01	0.045	0	0
Nucleotide Excision Repair	R-HSA-5696398	9.006929e-01	0.045	0	0
Telomere Maintenance	R-HSA-157579	9.013137e-01	0.045	0	0
Beta-catenin independent WNT signaling	R-HSA-3858494	9.016361e-01	0.045	0	0
Defective pyroptosis	R-HSA-9710421	9.024297e-01	0.045	0	0
Signaling by FLT3 ITD and TKD mutants	R-HSA-9703648	9.048659e-01	0.043	0	0
Mitochondrial RNA degradation	R-HSA-9836573	9.048659e-01	0.043	0	0
Recognition of DNA damage by PCNA-containing replication complex	R-HSA-110314	9.048659e-01	0.043	0	0
TNFs bind their physiological receptors	R-HSA-5669034	9.048659e-01	0.043	0	0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	R-HSA-9843970	9.053793e-01	0.043	0	0
SARS-CoV-1 modulates host translation machinery	R-HSA-9735869	9.053793e-01	0.043	0	0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	R-HSA-983170	9.053793e-01	0.043	0	0
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	9.057192e-01	0.043	1	0
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	9.057192e-01	0.043	1	0
SARS-CoV-1-host interactions	R-HSA-9692914	9.061286e-01	0.043	0	0
Respiratory Syncytial Virus Infection Pathway	R-HSA-9820952	9.064091e-01	0.043	0	0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV	R-HSA-9859138	9.066193e-01	0.043	0	0
CRMPs in Sema3A signaling	R-HSA-399956	9.066193e-01	0.043	0	0
Synthesis of IPs in the nucleus	R-HSA-1855191	9.066193e-01	0.043	0	0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	R-HSA-975163	9.066193e-01	0.043	0	0
cGMP effects	R-HSA-418457	9.066193e-01	0.043	0	0
Prolactin receptor signaling	R-HSA-1170546	9.066193e-01	0.043	0	0
NRIF signals cell death from the nucleus	R-HSA-205043	9.066193e-01	0.043	0	0
HDL assembly	R-HSA-8963896	9.066193e-01	0.043	0	0
P2Y receptors	R-HSA-417957	9.066193e-01	0.043	0	0
SARS-CoV-1 Genome Replication and Transcription	R-HSA-9679514	9.066193e-01	0.043	0	0
SARS-CoV-2 modulates host translation machinery	R-HSA-9754678	9.097213e-01	0.041	0	0
Base-Excision Repair, AP Site Formation	R-HSA-73929	9.097213e-01	0.041	0	0
DAP12 interactions	R-HSA-2172127	9.101943e-01	0.041	0	0
Amine ligand-binding receptors	R-HSA-375280	9.101943e-01	0.041	0	0
TP53 Regulates Metabolic Genes	R-HSA-5628897	9.107853e-01	0.041	0	0
Downstream signaling of activated FGFR2	R-HSA-5654696	9.137035e-01	0.039	0	0
Downstream signaling of activated FGFR1	R-HSA-5654687	9.137035e-01	0.039	0	0
PI-3K cascade:FGFR2	R-HSA-5654695	9.143991e-01	0.039	0	0
G protein gated Potassium channels	R-HSA-1296059	9.143991e-01	0.039	0	0
Activation of G protein gated Potassium channels	R-HSA-1296041	9.143991e-01	0.039	0	0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	R-HSA-997272	9.143991e-01	0.039	0	0
FRS-mediated FGFR1 signaling	R-HSA-5654693	9.143991e-01	0.039	0	0
Tight junction interactions	R-HSA-420029	9.143991e-01	0.039	0	0
Formation of the nephric duct	R-HSA-9830364	9.143991e-01	0.039	0	0
VEGFA-VEGFR2 Pathway	R-HSA-4420097	9.155891e-01	0.038	0	0
Global Genome Nucleotide Excision Repair (GG-NER)	R-HSA-5696399	9.158854e-01	0.038	0	0
Fanconi Anemia Pathway	R-HSA-6783310	9.174042e-01	0.037	0	0
HCMV Infection	R-HSA-9609646	9.174944e-01	0.037	0	0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	R-HSA-2173791	9.181506e-01	0.037	0	0
Adenylate cyclase inhibitory pathway	R-HSA-170670	9.181506e-01	0.037	0	0
G beta:gamma signalling through BTK	R-HSA-8964315	9.181506e-01	0.037	0	0
RNA Polymerase III Chain Elongation	R-HSA-73780	9.181506e-01	0.037	0	0
Translesion synthesis by REV1	R-HSA-110312	9.181506e-01	0.037	0	0
TRAF6-mediated induction of TAK1 complex within TLR4 complex	R-HSA-937072	9.181506e-01	0.037	0	0
RIP-mediated NFkB activation via ZBP1	R-HSA-1810476	9.181506e-01	0.037	0	0
TICAM1, RIP1-mediated IKK complex recruitment	R-HSA-168927	9.181506e-01	0.037	0	0
FASTK family proteins regulate processing and stability of mitochondrial RNAs	R-HSA-9837092	9.181506e-01	0.037	0	0
Protein lipoylation	R-HSA-9857492	9.181506e-01	0.037	0	0
Lysosphingolipid and LPA receptors	R-HSA-419408	9.181506e-01	0.037	0	0
IRF3-mediated induction of type I IFN	R-HSA-3270619	9.181506e-01	0.037	0	0
Activation of BAD and translocation to mitochondria	R-HSA-111447	9.181506e-01	0.037	0	0
Other semaphorin interactions	R-HSA-416700	9.181506e-01	0.037	0	0
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	R-HSA-6781827	9.188819e-01	0.037	0	0
Signaling by Insulin receptor	R-HSA-74752	9.189497e-01	0.037	1	0
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	9.198369e-01	0.036	1	0
DNA Replication Pre-Initiation	R-HSA-69002	9.209646e-01	0.036	0	0
PRC2 methylates histones and DNA	R-HSA-212300	9.213557e-01	0.036	0	0
Triglyceride catabolism	R-HSA-163560	9.213557e-01	0.036	0	0
Ion homeostasis	R-HSA-5578775	9.226902e-01	0.035	0	0
Adrenaline,noradrenaline inhibits insulin secretion	R-HSA-400042	9.230293e-01	0.035	0	0
TRP channels	R-HSA-3295583	9.230293e-01	0.035	0	0
Metalloprotease DUBs	R-HSA-5689901	9.230293e-01	0.035	0	0
Urea cycle	R-HSA-70635	9.230293e-01	0.035	0	0
MET activates PTK2 signaling	R-HSA-8874081	9.230293e-01	0.035	0	0
Caspase activation via extrinsic apoptotic signalling pathway	R-HSA-5357769	9.230293e-01	0.035	0	0
Synthesis of IP2, IP, and Ins in the cytosol	R-HSA-1855183	9.230293e-01	0.035	0	0
Macroautophagy	R-HSA-1632852	9.236319e-01	0.035	0	0
Formation of TC-NER Pre-Incision Complex	R-HSA-6781823	9.240916e-01	0.034	0	0
Translesion synthesis by POLI	R-HSA-5656121	9.282585e-01	0.032	0	0
Phosphorylation of the APC/C	R-HSA-176412	9.282585e-01	0.032	0	0
TP53 Regulates Transcription of Caspase Activators and Caspases	R-HSA-6803207	9.282585e-01	0.032	0	0
Phase 4 - resting membrane potential	R-HSA-5576886	9.282585e-01	0.032	0	0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	R-HSA-9634600	9.282585e-01	0.032	0	0
Induction of Cell-Cell Fusion	R-HSA-9733458	9.282585e-01	0.032	0	0
Fructose catabolism	R-HSA-70350	9.282585e-01	0.032	0	0
Regulation of NF-kappa B signaling	R-HSA-9758274	9.282585e-01	0.032	0	0
Activation of SMO	R-HSA-5635838	9.282585e-01	0.032	0	0
TRAF6 mediated IRF7 activation	R-HSA-933541	9.283822e-01	0.032	0	0
SIRT1 negatively regulates rRNA expression	R-HSA-427359	9.283822e-01	0.032	0	0
Collagen formation	R-HSA-1474290	9.285632e-01	0.032	0	0
Signaling by ROBO receptors	R-HSA-376176	9.302896e-01	0.031	0	0
Cristae formation	R-HSA-8949613	9.308341e-01	0.031	0	0
CD28 dependent PI3K/Akt signaling	R-HSA-389357	9.308341e-01	0.031	0	0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	R-HSA-8866652	9.308341e-01	0.031	0	0
KEAP1-NFE2L2 pathway	R-HSA-9755511	9.311297e-01	0.031	0	0
Dual incision in TC-NER	R-HSA-6782135	9.339799e-01	0.030	0	0
Biofilm formation	R-HSA-9931953	9.348273e-01	0.029	0	0
SLC-mediated transport of inorganic anions	R-HSA-9958790	9.348273e-01	0.029	0	0
Cargo recognition for clathrin-mediated endocytosis	R-HSA-8856825	9.352311e-01	0.029	0	0
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	9.355184e-01	0.029	0	0
Translesion synthesis by POLK	R-HSA-5655862	9.371187e-01	0.028	0	0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	R-HSA-975110	9.371187e-01	0.028	0	0
STAT5 activation downstream of FLT3 ITD mutants	R-HSA-9702518	9.371187e-01	0.028	0	0
Synthesis of PG	R-HSA-1483148	9.371187e-01	0.028	0	0
Scavenging by Class B Receptors	R-HSA-3000471	9.371187e-01	0.028	0	0
Acetylcholine regulates insulin secretion	R-HSA-399997	9.371187e-01	0.028	0	0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	R-HSA-9651496	9.371187e-01	0.028	0	0
Activation of AMPK downstream of NMDARs	R-HSA-9619483	9.378858e-01	0.028	0	0
FRS-mediated FGFR2 signaling	R-HSA-5654700	9.378858e-01	0.028	0	0
ATF4 activates genes in response to endoplasmic reticulum stress	R-HSA-380994	9.378858e-01	0.028	0	0
Integration of energy metabolism	R-HSA-163685	9.385252e-01	0.028	0	0
Plasma lipoprotein clearance	R-HSA-8964043	9.407332e-01	0.027	0	0
Respiratory syncytial virus (RSV) genome replication, transcription and translation	R-HSA-9820965	9.407332e-01	0.027	0	0
Cellular responses to mechanical stimuli	R-HSA-9855142	9.412657e-01	0.026	0	0
Cytosolic sensors of pathogen-associated DNA	R-HSA-1834949	9.428488e-01	0.026	0	0
Signaling by CSF3 (G-CSF)	R-HSA-9674555	9.442512e-01	0.025	0	0
Nitric oxide stimulates guanylate cyclase	R-HSA-392154	9.442512e-01	0.025	0	0
DARPP-32 events	R-HSA-180024	9.442512e-01	0.025	0	0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	R-HSA-190840	9.448851e-01	0.025	0	0
Sulfide oxidation to sulfate	R-HSA-1614517	9.448851e-01	0.025	0	0
Catecholamine biosynthesis	R-HSA-209905	9.448851e-01	0.025	0	0
Glycogen storage diseases	R-HSA-3229121	9.448851e-01	0.025	0	0
Replication of the SARS-CoV-2 genome	R-HSA-9694686	9.448851e-01	0.025	0	0
Attenuation phase	R-HSA-3371568	9.461397e-01	0.024	0	0
Co-inhibition by PD-1	R-HSA-389948	9.468413e-01	0.024	0	0
Regulation of mitotic cell cycle	R-HSA-453276	9.470385e-01	0.024	0	0
APC/C-mediated degradation of cell cycle proteins	R-HSA-174143	9.470385e-01	0.024	0	0
Formation of paraxial mesoderm	R-HSA-9793380	9.481563e-01	0.023	0	0
Regulation of RUNX2 expression and activity	R-HSA-8939902	9.481563e-01	0.023	0	0
Signaling by FGFR	R-HSA-190236	9.483937e-01	0.023	1	0
VEGFR2 mediated vascular permeability	R-HSA-5218920	9.510844e-01	0.022	0	0
Purine ribonucleoside monophosphate biosynthesis	R-HSA-73817	9.510844e-01	0.022	0	0
Chromatin modifications during the maternal to zygotic transition (MZT)	R-HSA-9821002	9.510844e-01	0.022	0	0
Degradation of the extracellular matrix	R-HSA-1474228	9.516553e-01	0.022	0	0
Trafficking of GluR2-containing AMPA receptors	R-HSA-416993	9.516927e-01	0.022	0	0
G beta:gamma signalling through PLC beta	R-HSA-418217	9.516927e-01	0.022	0	0
Transport of connexons to the plasma membrane	R-HSA-190872	9.516927e-01	0.022	0	0
PCNA-Dependent Long Patch Base Excision Repair	R-HSA-5651801	9.516927e-01	0.022	0	0
Presynaptic function of Kainate receptors	R-HSA-500657	9.516927e-01	0.022	0	0
PKA activation in glucagon signalling	R-HSA-164378	9.516927e-01	0.022	0	0
PKA activation	R-HSA-163615	9.516927e-01	0.022	0	0
ZBP1(DAI) mediated induction of type I IFNs	R-HSA-1606322	9.516927e-01	0.022	0	0
Organic anion transport by SLC5/17/25 transporters	R-HSA-428643	9.516927e-01	0.022	0	0
Platelet sensitization by LDL	R-HSA-432142	9.516927e-01	0.022	0	0
Nucleotide-like (purinergic) receptors	R-HSA-418038	9.516927e-01	0.022	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9679504	9.516927e-01	0.022	0	0
GTP hydrolysis and joining of the 60S ribosomal subunit	R-HSA-72706	9.527980e-01	0.021	0	0
L13a-mediated translational silencing of Ceruloplasmin expression	R-HSA-156827	9.527980e-01	0.021	0	0
Cap-dependent Translation Initiation	R-HSA-72737	9.540846e-01	0.020	0	0
Eukaryotic Translation Initiation	R-HSA-72613	9.540846e-01	0.020	0	0
Orc1 removal from chromatin	R-HSA-68949	9.549184e-01	0.020	0	0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	R-HSA-174184	9.549184e-01	0.020	0	0
E3 ubiquitin ligases ubiquitinate target proteins	R-HSA-8866654	9.549184e-01	0.020	0	0
Transcriptional Regulation by NPAS4	R-HSA-9634815	9.549184e-01	0.020	1	0
Negative regulators of DDX58/IFIH1 signaling	R-HSA-936440	9.551660e-01	0.020	0	0
Molecules associated with elastic fibres	R-HSA-2129379	9.551660e-01	0.020	0	0
Signaling by VEGF	R-HSA-194138	9.555079e-01	0.020	0	0
Scavenging by Class A Receptors	R-HSA-3000480	9.556026e-01	0.020	0	0
rRNA modification in the nucleus and cytosol	R-HSA-6790901	9.560100e-01	0.020	0	0
RUNX1 regulates transcription of genes involved in differentiation of HSCs	R-HSA-8939236	9.573740e-01	0.019	0	0
Cytokine Signaling in Immune system	R-HSA-1280215	9.573983e-01	0.019	1	0
Translesion Synthesis by POLH	R-HSA-110320	9.576597e-01	0.019	0	0
Prostacyclin signalling through prostacyclin receptor	R-HSA-392851	9.576597e-01	0.019	0	0
Pyrimidine biosynthesis	R-HSA-500753	9.576597e-01	0.019	0	0
IKK complex recruitment mediated by RIP1	R-HSA-937041	9.576597e-01	0.019	0	0
STING mediated induction of host immune responses	R-HSA-1834941	9.576597e-01	0.019	0	0
Maturation of nucleoprotein	R-HSA-9694631	9.576597e-01	0.019	0	0
Strand-asynchronous mitochondrial DNA replication	R-HSA-9913635	9.576597e-01	0.019	0	0
Other interleukin signaling	R-HSA-449836	9.576597e-01	0.019	0	0
SARS-CoV-2 Genome Replication and Transcription	R-HSA-9694682	9.576597e-01	0.019	0	0
Signaling by NOTCH4	R-HSA-9013694	9.580017e-01	0.019	0	0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	R-HSA-179419	9.587606e-01	0.018	0	0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	R-HSA-174178	9.587606e-01	0.018	0	0
Nucleotide biosynthesis	R-HSA-8956320	9.587606e-01	0.018	0	0
Activation of GABAB receptors	R-HSA-991365	9.597277e-01	0.018	0	0
GABA B receptor activation	R-HSA-977444	9.597277e-01	0.018	0	0
Incretin synthesis, secretion, and inactivation	R-HSA-400508	9.597277e-01	0.018	0	0
Inwardly rectifying K+ channels	R-HSA-1296065	9.598251e-01	0.018	0	0
TP53 Regulates Transcription of Cell Death Genes	R-HSA-5633008	9.611706e-01	0.017	0	0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	R-HSA-8950505	9.627621e-01	0.016	0	0
Formation of ATP by chemiosmotic coupling	R-HSA-163210	9.628900e-01	0.016	0	0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	R-HSA-9609523	9.628900e-01	0.016	0	0
BBSome-mediated cargo-targeting to cilium	R-HSA-5620922	9.628900e-01	0.016	0	0
Mitochondrial iron-sulfur cluster biogenesis	R-HSA-1362409	9.628900e-01	0.016	0	0
Wax and plasmalogen biosynthesis	R-HSA-8848584	9.628900e-01	0.016	0	0
Glycogen synthesis	R-HSA-3322077	9.628900e-01	0.016	0	0
Synthesis of Ketone Bodies	R-HSA-77111	9.628900e-01	0.016	0	0
Nephrin family interactions	R-HSA-373753	9.628900e-01	0.016	0	0
Assembly of the ORC complex at the origin of replication	R-HSA-68616	9.640176e-01	0.016	0	0
APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176409	9.655517e-01	0.015	0	0
Response of endothelial cells to shear stress	R-HSA-9860931	9.656528e-01	0.015	0	0
G-protein activation	R-HSA-202040	9.674745e-01	0.014	0	0
ADP signalling through P2Y purinoceptor 12	R-HSA-392170	9.674745e-01	0.014	0	0
SHC-mediated cascade:FGFR3	R-HSA-5654704	9.674745e-01	0.014	0	0
NOTCH2 Activation and Transmission of Signal to the Nucleus	R-HSA-2979096	9.674745e-01	0.014	0	0
PKA-mediated phosphorylation of CREB	R-HSA-111931	9.674745e-01	0.014	0	0
Basigin interactions	R-HSA-210991	9.674745e-01	0.014	0	0
Glucagon signaling in metabolic regulation	R-HSA-163359	9.677877e-01	0.014	0	0
Effects of PIP2 hydrolysis	R-HSA-114508	9.677877e-01	0.014	0	0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane	R-HSA-9768727	9.677877e-01	0.014	0	0
Heme degradation	R-HSA-189483	9.677877e-01	0.014	0	0
Interleukin-12 family signaling	R-HSA-447115	9.684363e-01	0.014	0	0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176814	9.685425e-01	0.014	0	0
Regulated Necrosis	R-HSA-5218859	9.711198e-01	0.013	0	0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	R-HSA-3371497	9.711198e-01	0.013	0	0
SLC transporter disorders	R-HSA-5619102	9.711337e-01	0.013	0	0
Developmental Lineage of Mammary Gland Alveolar Cells	R-HSA-9927426	9.711757e-01	0.013	0	0
Mitophagy	R-HSA-5205647	9.711757e-01	0.013	0	0
SHC-mediated cascade:FGFR4	R-HSA-5654719	9.714929e-01	0.013	0	0
Inactivation of CSF3 (G-CSF) signaling	R-HSA-9705462	9.714929e-01	0.013	0	0
Molybdenum cofactor biosynthesis	R-HSA-947581	9.714929e-01	0.013	0	0
Glutathione synthesis and recycling	R-HSA-174403	9.714929e-01	0.013	0	0
Mitochondrial calcium ion transport	R-HSA-8949215	9.714929e-01	0.013	0	0
Metabolism of Angiotensinogen to Angiotensins	R-HSA-2022377	9.714929e-01	0.013	0	0
Cellular response to starvation	R-HSA-9711097	9.718185e-01	0.012	0	0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	R-HSA-9856530	9.739806e-01	0.011	0	0
Synthesis of DNA	R-HSA-69239	9.740667e-01	0.011	0	0
Defects in vitamin and cofactor metabolism	R-HSA-3296482	9.742186e-01	0.011	0	0
Cellular response to chemical stress	R-HSA-9711123	9.743458e-01	0.011	0	0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	R-HSA-9857377	9.750150e-01	0.011	0	0
Fructose metabolism	R-HSA-5652084	9.750150e-01	0.011	0	0
Ethanol oxidation	R-HSA-71384	9.750150e-01	0.011	0	0
Cellular hexose transport	R-HSA-189200	9.750150e-01	0.011	0	0
LDL clearance	R-HSA-8964038	9.750150e-01	0.011	0	0
TAK1-dependent IKK and NF-kappa-B activation	R-HSA-445989	9.754741e-01	0.011	0	0
SARS-CoV-2 Infection	R-HSA-9694516	9.754861e-01	0.011	0	0
HSF1 activation	R-HSA-3371511	9.769497e-01	0.010	0	0
Glycosphingolipid transport	R-HSA-9845576	9.769497e-01	0.010	0	0
FGFR2 mutant receptor activation	R-HSA-1839126	9.769497e-01	0.010	0	0
Developmental Cell Lineages of the Exocrine Pancreas	R-HSA-9820448	9.772152e-01	0.010	0	0
ECM proteoglycans	R-HSA-3000178	9.777084e-01	0.010	0	0
Metal ion SLC transporters	R-HSA-425410	9.778245e-01	0.010	0	0
G beta:gamma signalling through PI3Kgamma	R-HSA-392451	9.781021e-01	0.010	0	0
Synthesis of pyrophosphates in the cytosol	R-HSA-1855167	9.781021e-01	0.010	0	0
Mitochondrial mRNA modification	R-HSA-9937008	9.781021e-01	0.010	0	0
Free fatty acids regulate insulin secretion	R-HSA-400451	9.781021e-01	0.010	0	0
Organic anion transport by SLCO transporters	R-HSA-879518	9.781021e-01	0.010	0	0
Ketone body metabolism	R-HSA-74182	9.781021e-01	0.010	0	0
Syndecan interactions	R-HSA-3000170	9.781021e-01	0.010	0	0
Signaling by Retinoic Acid	R-HSA-5362517	9.782421e-01	0.010	0	0
Sphingolipid de novo biosynthesis	R-HSA-1660661	9.782421e-01	0.010	0	0
Glutathione conjugation	R-HSA-156590	9.782421e-01	0.010	0	0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	R-HSA-975956	9.785633e-01	0.009	0	0
Developmental Cell Lineages	R-HSA-9734767	9.789003e-01	0.009	0	0
Degradation of AXIN	R-HSA-4641257	9.793998e-01	0.009	0	0
Voltage gated Potassium channels	R-HSA-1296072	9.793998e-01	0.009	0	0
SLC-mediated transport of organic cations	R-HSA-549127	9.793998e-01	0.009	0	0
Toll-like Receptor Cascades	R-HSA-168898	9.797641e-01	0.009	1	0
Gap junction trafficking and regulation	R-HSA-157858	9.799593e-01	0.009	0	0
p53-Dependent G1 DNA Damage Response	R-HSA-69563	9.799593e-01	0.009	0	0
p53-Dependent G1/S DNA damage checkpoint	R-HSA-69580	9.799593e-01	0.009	0	0
Endogenous sterols	R-HSA-211976	9.801832e-01	0.009	0	0
Eukaryotic Translation Elongation	R-HSA-156842	9.801879e-01	0.009	0	0
Translocation of ZAP-70 to Immunological synapse	R-HSA-202430	9.808079e-01	0.008	0	0
Thromboxane signalling through TP receptor	R-HSA-428930	9.808079e-01	0.008	0	0
SHC-mediated cascade:FGFR1	R-HSA-5654688	9.808079e-01	0.008	0	0
TRAF6 mediated NF-kB activation	R-HSA-933542	9.808079e-01	0.008	0	0
ADP signalling through P2Y purinoceptor 1	R-HSA-418592	9.808079e-01	0.008	0	0
Complex III assembly	R-HSA-9865881	9.808079e-01	0.008	0	0
Plasma lipoprotein assembly	R-HSA-8963898	9.808079e-01	0.008	0	0
Regulation of T cell activation by CD28 family	R-HSA-388841	9.810098e-01	0.008	0	0
Switching of origins to a post-replicative state	R-HSA-69052	9.812898e-01	0.008	0	0
Transport to the Golgi and subsequent modification	R-HSA-948021	9.815236e-01	0.008	0	0
Metabolism of nitric oxide: NOS3 activation and regulation	R-HSA-202131	9.815965e-01	0.008	0	0
Elastic fibre formation	R-HSA-1566948	9.815965e-01	0.008	0	0
Nonsense-Mediated Decay (NMD)	R-HSA-927802	9.819310e-01	0.008	0	0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	R-HSA-975957	9.819310e-01	0.008	0	0
Regulation of APC/C activators between G1/S and early anaphase	R-HSA-176408	9.819599e-01	0.008	0	0
Interferon Signaling	R-HSA-913531	9.830150e-01	0.007	1	0
Neurotransmitter receptors and postsynaptic signal transmission	R-HSA-112314	9.831310e-01	0.007	1	0
Defects in cobalamin (B12) metabolism	R-HSA-3296469	9.831796e-01	0.007	0	0
MicroRNA (miRNA) biogenesis	R-HSA-203927	9.831796e-01	0.007	0	0
Fertilization	R-HSA-1187000	9.831796e-01	0.007	0	0
PIWI-interacting RNA (piRNA) biogenesis	R-HSA-5601884	9.831796e-01	0.007	0	0
Stabilization of p53	R-HSA-69541	9.835650e-01	0.007	0	0
G1/S DNA Damage Checkpoints	R-HSA-69615	9.835850e-01	0.007	0	0
Meiotic recombination	R-HSA-912446	9.836549e-01	0.007	0	0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	R-HSA-9954716	9.844021e-01	0.007	0	0
SARS-CoV-1 activates/modulates innate immune responses	R-HSA-9692916	9.852485e-01	0.006	0	0
Diseases of branched-chain amino acid catabolism	R-HSA-9865118	9.852582e-01	0.006	0	0
Sphingolipid catabolism	R-HSA-9845614	9.852582e-01	0.006	0	0
Regulation of RUNX3 expression and activity	R-HSA-8941858	9.853282e-01	0.006	0	0
Formation of Incision Complex in GG-NER	R-HSA-5696395	9.853282e-01	0.006	0	0
Formation of a pool of free 40S subunits	R-HSA-72689	9.856101e-01	0.006	0	0
Interleukin-12 signaling	R-HSA-9020591	9.856638e-01	0.006	0	0
Chaperonin-mediated protein folding	R-HSA-390466	9.866357e-01	0.006	0	0
Amino acids regulate mTORC1	R-HSA-9639288	9.866925e-01	0.006	0	0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	9.869068e-01	0.006	0	0
Maturation of spike protein	R-HSA-9694548	9.869068e-01	0.006	0	0
Platelet homeostasis	R-HSA-418346	9.870599e-01	0.006	0	0
RNA Polymerase I Promoter Opening	R-HSA-73728	9.870801e-01	0.006	1	1
Phosphorylation of CD3 and TCR zeta chains	R-HSA-202427	9.870801e-01	0.006	0	0
Cobalamin (Cbl) metabolism	R-HSA-9759218	9.870801e-01	0.006	0	0
SHC-mediated cascade:FGFR2	R-HSA-5654699	9.870801e-01	0.006	0	0
EPHA-mediated growth cone collapse	R-HSA-3928663	9.870801e-01	0.006	0	0
ER Quality Control Compartment (ERQC)	R-HSA-901032	9.870801e-01	0.006	0	0
Major pathway of rRNA processing in the nucleolus and cytosol	R-HSA-6791226	9.872780e-01	0.006	0	0
tRNA modification in the nucleus and cytosol	R-HSA-6782315	9.876676e-01	0.005	0	0
Peptide chain elongation	R-HSA-156902	9.877288e-01	0.005	0	0
Integrin cell surface interactions	R-HSA-216083	9.880228e-01	0.005	0	0
SRP-dependent cotranslational protein targeting to membrane	R-HSA-1799339	9.880341e-01	0.005	0	0
Degradation of CRY and PER proteins	R-HSA-9932298	9.883194e-01	0.005	0	0
SLC-mediated transport of neurotransmitters	R-HSA-442660	9.883194e-01	0.005	0	0
Heme biosynthesis	R-HSA-189451	9.883194e-01	0.005	0	0
DNA Replication	R-HSA-69306	9.886316e-01	0.005	0	0
PINK1-PRKN Mediated Mitophagy	R-HSA-5205685	9.886770e-01	0.005	0	0
Pyrimidine salvage	R-HSA-73614	9.886770e-01	0.005	0	0
Pyroptosis	R-HSA-5620971	9.886770e-01	0.005	0	0
Neurotransmitter release cycle	R-HSA-112310	9.896673e-01	0.005	0	0
DNA methylation	R-HSA-5334118	9.900765e-01	0.004	0	0
Activation of Matrix Metalloproteinases	R-HSA-1592389	9.900765e-01	0.004	0	0
Glucagon-type ligand receptors	R-HSA-420092	9.900765e-01	0.004	0	0
Muscle contraction	R-HSA-397014	9.902372e-01	0.004	0	0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	R-HSA-9954714	9.905244e-01	0.004	0	0
Synthesis of very long-chain fatty acyl-CoAs	R-HSA-75876	9.907126e-01	0.004	0	0
Amyloid fiber formation	R-HSA-977225	9.908834e-01	0.004	0	0
Extra-nuclear estrogen signaling	R-HSA-9009391	9.912061e-01	0.004	1	0
Synthesis of PA	R-HSA-1483166	9.912225e-01	0.004	0	0
Dectin-2 family	R-HSA-5621480	9.912225e-01	0.004	0	0
Thrombin signalling through proteinase activated receptors (PARs)	R-HSA-456926	9.913032e-01	0.004	1	1
GABA synthesis, release, reuptake and degradation	R-HSA-888590	9.913032e-01	0.004	0	0
Neurotransmitter clearance	R-HSA-112311	9.913032e-01	0.004	0	0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	R-HSA-1474151	9.913032e-01	0.004	0	0
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	9.916278e-01	0.004	0	0
Senescence-Associated Secretory Phenotype (SASP)	R-HSA-2559582	9.916831e-01	0.004	1	1
Gap junction trafficking	R-HSA-190828	9.917223e-01	0.004	0	0
Cobalamin (Cbl, vitamin B12) transport and metabolism	R-HSA-196741	9.917223e-01	0.004	0	0
Surfactant metabolism	R-HSA-5683826	9.917223e-01	0.004	0	0
Protein folding	R-HSA-391251	9.920409e-01	0.003	0	0
Early SARS-CoV-2 Infection Events	R-HSA-9772572	9.920974e-01	0.003	0	0
Respiratory syncytial virus (RSV) attachment and entry	R-HSA-9820960	9.923782e-01	0.003	0	0
Hedgehog 'on' state	R-HSA-5632684	9.924082e-01	0.003	0	0
Diseases associated with O-glycosylation of proteins	R-HSA-3906995	9.924082e-01	0.003	0	0
Metabolism of porphyrins	R-HSA-189445	9.924082e-01	0.003	0	0
rRNA processing in the nucleus and cytosol	R-HSA-8868773	9.924648e-01	0.003	0	0
Asymmetric localization of PCP proteins	R-HSA-4608870	9.926243e-01	0.003	0	0
ADORA2B mediated anti-inflammatory cytokines production	R-HSA-9660821	9.926243e-01	0.003	0	0
Vasopressin regulates renal water homeostasis via Aquaporins	R-HSA-432040	9.926243e-01	0.003	0	0
Degradation of cysteine and homocysteine	R-HSA-1614558	9.926243e-01	0.003	0	0
Assembly of the pre-replicative complex	R-HSA-68867	9.927099e-01	0.003	0	0
Triglyceride metabolism	R-HSA-8979227	9.928877e-01	0.003	0	0
Regulation of mRNA stability by proteins that bind AU-rich elements	R-HSA-450531	9.931185e-01	0.003	0	0
Regulation of actin dynamics for phagocytic cup formation	R-HSA-2029482	9.932220e-01	0.003	1	1
Cell recruitment (pro-inflammatory response)	R-HSA-9664424	9.934299e-01	0.003	0	0
Purinergic signaling in leishmaniasis infection	R-HSA-9660826	9.934299e-01	0.003	0	0
Phospholipid metabolism	R-HSA-1483257	9.935311e-01	0.003	0	0
GABA receptor activation	R-HSA-977443	9.936012e-01	0.003	0	0
Sealing of the nuclear envelope (NE) by ESCRT-III	R-HSA-9668328	9.941463e-01	0.003	0	0
Diseases associated with glycosylation precursor biosynthesis	R-HSA-5609975	9.941463e-01	0.003	0	0
APC/C:Cdc20 mediated degradation of Securin	R-HSA-174154	9.941491e-01	0.003	0	0
Eukaryotic Translation Termination	R-HSA-72764	9.944109e-01	0.002	0	0
Intraflagellar transport	R-HSA-5620924	9.947910e-01	0.002	0	0
GPER1 signaling	R-HSA-9634597	9.947910e-01	0.002	0	0
Acyl chain remodelling of PC	R-HSA-1482788	9.948700e-01	0.002	0	0
Vitamin B5 (pantothenate) metabolism	R-HSA-199220	9.948700e-01	0.002	0	0
Protein ubiquitination	R-HSA-8852135	9.948865e-01	0.002	0	0
SARS-CoV-1 Infection	R-HSA-9678108	9.953046e-01	0.002	0	0
Dual Incision in GG-NER	R-HSA-5696400	9.955043e-01	0.002	0	0
eNOS activation	R-HSA-203615	9.955043e-01	0.002	0	0
Signal amplification	R-HSA-392518	9.955043e-01	0.002	0	0
Gap junction assembly	R-HSA-190861	9.955043e-01	0.002	0	0
Autodegradation of the E3 ubiquitin ligase COP1	R-HSA-349425	9.955043e-01	0.002	0	0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	R-HSA-6814122	9.955043e-01	0.002	0	0
RA biosynthesis pathway	R-HSA-5365859	9.955043e-01	0.002	0	0
Calnexin/calreticulin cycle	R-HSA-901042	9.955043e-01	0.002	0	0
NPAS4 regulates expression of target genes	R-HSA-9768919	9.955043e-01	0.002	1	1
Regulation of insulin secretion	R-HSA-422356	9.957293e-01	0.002	0	0
Regulation of RAS by GAPs	R-HSA-5658442	9.958743e-01	0.002	0	0
SCF-beta-TrCP mediated degradation of Emi1	R-HSA-174113	9.960602e-01	0.002	0	0
Acyl chain remodelling of PE	R-HSA-1482839	9.960602e-01	0.002	0	0
Transferrin endocytosis and recycling	R-HSA-917977	9.960602e-01	0.002	0	0
PCP/CE pathway	R-HSA-4086400	9.962124e-01	0.002	0	0
Hedgehog ligand biogenesis	R-HSA-5358346	9.963296e-01	0.002	0	0
Cytosolic sulfonation of small molecules	R-HSA-156584	9.963296e-01	0.002	0	0
AUF1 (hnRNP D0) binds and destabilizes mRNA	R-HSA-450408	9.965474e-01	0.002	0	0
Lysosome Vesicle Biogenesis	R-HSA-432720	9.965474e-01	0.002	0	0
Calmodulin induced events	R-HSA-111933	9.965474e-01	0.002	0	0
CaM pathway	R-HSA-111997	9.965474e-01	0.002	0	0
FCGR3A-mediated phagocytosis	R-HSA-9664422	9.967437e-01	0.001	1	1
Parasite infection	R-HSA-9664407	9.967437e-01	0.001	1	0
Leishmania phagocytosis	R-HSA-9664417	9.967437e-01	0.001	1	0
Selenocysteine synthesis	R-HSA-2408557	9.967470e-01	0.001	0	0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	R-HSA-9762114	9.969744e-01	0.001	0	0
Degradation of DVL	R-HSA-4641258	9.969744e-01	0.001	0	0
Beta-oxidation of very long chain fatty acids	R-HSA-390247	9.969744e-01	0.001	0	0
Metabolism of folate and pterines	R-HSA-196757	9.969744e-01	0.001	0	0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	R-HSA-193368	9.969754e-01	0.001	0	0
Class I MHC mediated antigen processing & presentation	R-HSA-983169	9.969915e-01	0.001	0	0
C-type lectin receptors (CLRs)	R-HSA-5621481	9.970101e-01	0.001	0	0
Regulation of PTEN stability and activity	R-HSA-8948751	9.970971e-01	0.001	0	0
O-linked glycosylation of mucins	R-HSA-913709	9.972858e-01	0.001	0	0
Viral mRNA Translation	R-HSA-192823	9.972915e-01	0.001	0	0
tRNA processing in the mitochondrion	R-HSA-6785470	9.973486e-01	0.001	0	0
CDK-mediated phosphorylation and removal of Cdc6	R-HSA-69017	9.974192e-01	0.001	0	0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	R-HSA-381771	9.976765e-01	0.001	0	0
G alpha (z) signalling events	R-HSA-418597	9.977061e-01	0.001	0	0
SARS-CoV Infections	R-HSA-9679506	9.979158e-01	0.001	0	0
rRNA processing in the mitochondrion	R-HSA-8868766	9.979639e-01	0.001	0	0
Maturation of TCA enzymes and regulation of TCA cycle	R-HSA-9854311	9.979639e-01	0.001	0	0
Glycogen metabolism	R-HSA-8982491	9.979639e-01	0.001	0	0
NIK-->noncanonical NF-kB signaling	R-HSA-5676590	9.982157e-01	0.001	0	0
Ion channel transport	R-HSA-983712	9.982786e-01	0.001	0	0
Peptide hormone metabolism	R-HSA-2980736	9.983073e-01	0.001	0	0
Potassium Channels	R-HSA-1296071	9.983484e-01	0.001	0	0
CLEC7A (Dectin-1) signaling	R-HSA-5607764	9.983484e-01	0.001	0	0
Degradation of GLI2 by the proteasome	R-HSA-5610783	9.984365e-01	0.001	0	0
GLI3 is processed to GLI3R by the proteasome	R-HSA-5610785	9.984365e-01	0.001	0	0
Degradation of GLI1 by the proteasome	R-HSA-5610780	9.984365e-01	0.001	0	0
Translation of Structural Proteins	R-HSA-9683701	9.984365e-01	0.001	0	0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	R-HSA-163841	9.984875e-01	0.001	0	0
Peroxisomal protein import	R-HSA-9033241	9.985711e-01	0.001	0	0
ROS and RNS production in phagocytes	R-HSA-1222556	9.985908e-01	0.001	0	0
Ca-dependent events	R-HSA-111996	9.986299e-01	0.001	0	0
Potential therapeutics for SARS	R-HSA-9679191	9.986590e-01	0.001	0	0
TCR signaling	R-HSA-202403	9.987147e-01	0.001	0	0
Iron uptake and transport	R-HSA-917937	9.987378e-01	0.001	0	0
Pyrimidine catabolism	R-HSA-73621	9.987994e-01	0.001	0	0
Response of Mtb to phagocytosis	R-HSA-9637690	9.987994e-01	0.001	1	0
Cardiac conduction	R-HSA-5576891	9.988452e-01	0.001	0	0
Aquaporin-mediated transport	R-HSA-445717	9.988736e-01	0.000	0	0
Hedgehog 'off' state	R-HSA-5610787	9.988861e-01	0.000	0	0
FCERI mediated MAPK activation	R-HSA-2871796	9.989364e-01	0.000	1	1
Fcgamma receptor (FCGR) dependent phagocytosis	R-HSA-2029480	9.989430e-01	0.000	1	0
Synthesis of Leukotrienes (LT) and Eoxins (EX)	R-HSA-2142691	9.989479e-01	0.000	0	0
Translation of Structural Proteins	R-HSA-9694635	9.989881e-01	0.000	0	0
Interleukin-1 signaling	R-HSA-9020702	9.989913e-01	0.000	0	0
Mitochondrial protein import	R-HSA-1268020	9.990002e-01	0.000	0	0
Class B/2 (Secretin family receptors)	R-HSA-373080	9.990018e-01	0.000	0	0
Dectin-1 mediated noncanonical NF-kB signaling	R-HSA-5607761	9.990781e-01	0.000	0	0
Somitogenesis	R-HSA-9824272	9.990781e-01	0.000	0	0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A	R-HSA-69601	9.990781e-01	0.000	0	0
p53-Independent G1/S DNA Damage Checkpoint	R-HSA-69613	9.990781e-01	0.000	0	0
Diseases associated with glycosaminoglycan metabolism	R-HSA-3560782	9.990781e-01	0.000	0	0
DAG and IP3 signaling	R-HSA-1489509	9.990781e-01	0.000	0	0
Interleukin-10 signaling	R-HSA-6783783	9.990944e-01	0.000	0	0
Complex I biogenesis	R-HSA-6799198	9.991127e-01	0.000	0	0
Autodegradation of Cdh1 by Cdh1:APC/C	R-HSA-174084	9.991922e-01	0.000	0	0
Regulation of pyruvate metabolism	R-HSA-9861718	9.991922e-01	0.000	0	0
Ion transport by P-type ATPases	R-HSA-936837	9.992126e-01	0.000	0	0
Plasma lipoprotein assembly, remodeling, and clearance	R-HSA-174824	9.992712e-01	0.000	0	0
Late SARS-CoV-2 Infection Events	R-HSA-9772573	9.992712e-01	0.000	0	0
Carboxyterminal post-translational modifications of tubulin	R-HSA-8955332	9.992922e-01	0.000	0	0
Synthesis of PC	R-HSA-1483191	9.992922e-01	0.000	0	0
Transmission across Chemical Synapses	R-HSA-112315	9.992922e-01	0.000	1	0
rRNA processing	R-HSA-72312	9.993099e-01	0.000	0	0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	R-HSA-983695	9.993440e-01	0.000	0	0
Platelet degranulation	R-HSA-114608	9.993810e-01	0.000	0	0
Mitochondrial protein degradation	R-HSA-9837999	9.994098e-01	0.000	0	0
Ribosome-associated quality control	R-HSA-9948299	9.994337e-01	0.000	0	0
Signaling by Hedgehog	R-HSA-5358351	9.994337e-01	0.000	0	0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	R-HSA-532668	9.994565e-01	0.000	0	0
DDX58/IFIH1-mediated induction of interferon-alpha/beta	R-HSA-168928	9.994690e-01	0.000	0	0
TNFR2 non-canonical NF-kB pathway	R-HSA-5668541	9.994816e-01	0.000	0	0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide	R-HSA-9954709	9.995225e-01	0.000	0	0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	R-HSA-2162123	9.995238e-01	0.000	0	0
Regulation of expression of SLITs and ROBOs	R-HSA-9010553	9.995737e-01	0.000	0	0
Branched-chain amino acid catabolism	R-HSA-70895	9.995827e-01	0.000	0	0
Complex IV assembly	R-HSA-9864848	9.995827e-01	0.000	0	0
Adaptive Immune System	R-HSA-1280218	9.996157e-01	0.000	0	0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)	R-HSA-9931269	9.996344e-01	0.000	0	0
Metabolism of cofactors	R-HSA-8978934	9.996605e-01	0.000	0	0
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	9.996791e-01	0.000	0	0
Platelet activation, signaling and aggregation	R-HSA-76002	9.996791e-01	0.000	1	0
Paracetamol ADME	R-HSA-9753281	9.997540e-01	0.000	0	0
Chondroitin sulfate/dermatan sulfate metabolism	R-HSA-1793185	9.997540e-01	0.000	0	0
Metabolism of amine-derived hormones	R-HSA-209776	9.997845e-01	0.000	0	0
Detoxification of Reactive Oxygen Species	R-HSA-3299685	9.997845e-01	0.000	0	0
Downstream TCR signaling	R-HSA-202424	9.997899e-01	0.000	0	0
Citric acid cycle (TCA cycle)	R-HSA-71403	9.997907e-01	0.000	0	0
Opioid Signalling	R-HSA-111885	9.998180e-01	0.000	0	0
FCERI mediated Ca+2 mobilization	R-HSA-2871809	9.998203e-01	0.000	0	0
SLC-mediated transport of organic anions	R-HSA-9955298	9.998546e-01	0.000	0	0
Cholesterol biosynthesis	R-HSA-191273	9.998546e-01	0.000	0	0
Amino acid transport across the plasma membrane	R-HSA-352230	9.998550e-01	0.000	0	0
Neddylation	R-HSA-8951664	9.998673e-01	0.000	0	0
Nucleotide salvage	R-HSA-8956321	9.998887e-01	0.000	0	0
PLC beta mediated events	R-HSA-112043	9.998887e-01	0.000	0	0
Disorders of transmembrane transporters	R-HSA-5619115	9.999020e-01	0.000	0	0
The role of GTSE1 in G2/M progression after G2 checkpoint	R-HSA-8852276	9.999025e-01	0.000	0	0
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	9.999191e-01	0.000	0	0
Xenobiotics	R-HSA-211981	9.999252e-01	0.000	0	0
Interferon gamma signaling	R-HSA-877300	9.999265e-01	0.000	1	1
Neuronal System	R-HSA-112316	9.999314e-01	0.000	1	0
Synthesis of bile acids and bile salts	R-HSA-192105	9.999405e-01	0.000	0	0
ABC-family proteins mediated transport	R-HSA-382556	9.999470e-01	0.000	0	0
G-protein mediated events	R-HSA-112040	9.999497e-01	0.000	0	0
Nicotinate metabolism	R-HSA-196807	9.999497e-01	0.000	0	0
SLC-mediated transport of amino acids	R-HSA-9958863	9.999497e-01	0.000	0	0
Sulfur amino acid metabolism	R-HSA-1614635	9.999516e-01	0.000	0	0
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	9.999655e-01	0.000	1	0
Retinoid metabolism and transport	R-HSA-975634	9.999704e-01	0.000	0	0
Interconversion of nucleotide di- and triphosphates	R-HSA-499943	9.999740e-01	0.000	0	0
Diseases of carbohydrate metabolism	R-HSA-5663084	9.999772e-01	0.000	0	0
G alpha (s) signalling events	R-HSA-418555	9.999790e-01	0.000	0	0
Mitochondrial translation termination	R-HSA-5419276	9.999834e-01	0.000	0	0
Parasitic Infection Pathways	R-HSA-9824443	9.999845e-01	0.000	1	0
Leishmania infection	R-HSA-9658195	9.999845e-01	0.000	1	0
Bile acid and bile salt metabolism	R-HSA-194068	9.999853e-01	0.000	0	0
Glycerophospholipid biosynthesis	R-HSA-1483206	9.999888e-01	0.000	0	0
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	9.999890e-01	0.000	0	0
Mitochondrial translation elongation	R-HSA-5389840	9.999890e-01	0.000	0	0
Extracellular matrix organization	R-HSA-1474244	9.999900e-01	0.000	0	0
Post-translational protein phosphorylation	R-HSA-8957275	9.999914e-01	0.000	0	0
Mitochondrial translation initiation	R-HSA-5368286	9.999914e-01	0.000	0	0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	R-HSA-381426	9.999918e-01	0.000	0	0
Metabolism of fat-soluble vitamins	R-HSA-6806667	9.999921e-01	0.000	0	0
Metabolism of steroids	R-HSA-8957322	9.999927e-01	0.000	0	0
Peroxisomal lipid metabolism	R-HSA-390918	9.999947e-01	0.000	0	0
Regulation of PD-L1(CD274) Post-translational modification	R-HSA-9909615	9.999959e-01	0.000	0	0
Pyruvate metabolism	R-HSA-70268	9.999969e-01	0.000	0	0
Viral Infection Pathways	R-HSA-9824446	9.999969e-01	0.000	0	0
Selenoamino acid metabolism	R-HSA-2408522	9.999970e-01	0.000	0	0
Hemostasis	R-HSA-109582	9.999972e-01	0.000	1	0
Formation of the cornified envelope	R-HSA-6809371	9.999978e-01	0.000	0	0
Protein localization	R-HSA-9609507	9.999980e-01	0.000	0	0
Mitochondrial Fatty Acid Beta-Oxidation	R-HSA-77289	9.999991e-01	0.000	0	0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	R-HSA-198933	9.999992e-01	0.000	0	0
Interferon alpha/beta signaling	R-HSA-909733	9.999993e-01	0.000	0	0
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	9.999995e-01	0.000	0	0
O-linked glycosylation	R-HSA-5173105	9.999997e-01	0.000	0	0
Diseases of glycosylation	R-HSA-3781865	9.999997e-01	0.000	0	0
Mitochondrial translation	R-HSA-5368287	9.999997e-01	0.000	0	0
Mitochondrial ribosome-associated quality control	R-HSA-9937383	9.999997e-01	0.000	0	0
Post-translational modification: synthesis of GPI-anchored proteins	R-HSA-163125	9.999998e-01	0.000	0	0
Antigen processing-Cross presentation	R-HSA-1236975	9.999999e-01	0.000	0	0
Nucleotide catabolism	R-HSA-8956319	9.999999e-01	0.000	0	0
G alpha (q) signalling events	R-HSA-416476	9.999999e-01	0.000	1	0
Cell surface interactions at the vascular wall	R-HSA-202733	9.999999e-01	0.000	0	0
Antimicrobial peptides	R-HSA-6803157	9.999999e-01	0.000	0	0
Sensory perception of taste	R-HSA-9717189	9.999999e-01	0.000	0	0
Cytochrome P450 - arranged by substrate type	R-HSA-211897	9.999999e-01	0.000	0	0
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	1.000000e+00	0.000	0	0
Role of phospholipids in phagocytosis	R-HSA-2029485	1.000000e+00	0.000	0	0
Infection with Mycobacterium tuberculosis	R-HSA-9635486	1.000000e+00	0.000	1	0
Respiratory electron transport	R-HSA-611105	1.000000e+00	0.000	0	0
FCGR3A-mediated IL10 synthesis	R-HSA-9664323	1.000000e+00	0.000	0	0
Sphingolipid metabolism	R-HSA-428157	1.000000e+00	0.000	0	0
Metabolism of nucleotides	R-HSA-15869	1.000000e+00	0.000	0	0
Asparagine N-linked glycosylation	R-HSA-446203	1.000000e+00	0.000	0	0
Arachidonate metabolism	R-HSA-2142753	1.000000e+00	0.000	0	0
Synthesis of substrates in N-glycan biosythesis	R-HSA-446219	1.000000e+00	0.000	0	0
Leishmania parasite growth and survival	R-HSA-9664433	1.000000e+00	0.000	0	0
Anti-inflammatory response favouring Leishmania parasite infection	R-HSA-9662851	1.000000e+00	0.000	0	0
Drug ADME	R-HSA-9748784	1.000000e+00	0.000	0	0
Post-translational protein modification	R-HSA-597592	1.000000e+00	0.000	0	0
Phase II - Conjugation of compounds	R-HSA-156580	1.000000e+00	0.000	0	0
Neutrophil degranulation	R-HSA-6798695	1.000000e+00	0.000	0	0
FCERI mediated NF-kB activation	R-HSA-2871837	1.000000e+00	0.000	0	0
Visual phototransduction	R-HSA-2187338	1.000000e+00	0.000	0	0
Translation	R-HSA-72766	1.000000e+00	0.000	0	0
Immune System	R-HSA-168256	1.000000e+00	0.000	1	0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	R-HSA-446193	1.000000e+00	0.000	0	0
Infection with Enterobacteria	R-HSA-9640148	1.000000e+00	0.000	0	0
Keratinization	R-HSA-6805567	1.000000e+00	0.000	0	0
Metabolism of carbohydrates and carbohydrate derivatives	R-HSA-71387	1.000000e+00	0.000	0	0
Bacterial Infection Pathways	R-HSA-9824439	1.000000e+00	0.000	1	0
SLC-mediated transmembrane transport	R-HSA-425407	1.000000e+00	0.000	0	0
Peptide ligand-binding receptors	R-HSA-375276	1.000000e+00	0.000	0	0
Phase I - Functionalization of compounds	R-HSA-211945	1.000000e+00	0.000	0	0
Glycosaminoglycan metabolism	R-HSA-1630316	1.000000e+00	0.000	0	0
Fatty acid metabolism	R-HSA-8978868	1.000000e+00	0.000	0	0
Metabolism of vitamins and cofactors	R-HSA-196854	1.000000e+00	0.000	0	0
Disease	R-HSA-1643685	1.000000e+00	0.000	1	0
GPCR downstream signalling	R-HSA-388396	1.000000e+00	0.000	1	0
Infectious disease	R-HSA-5663205	1.000000e+00	0.000	1	0
Aerobic respiration and respiratory electron transport	R-HSA-1428517	1.000000e+00	0.000	0	0
Diseases of metabolism	R-HSA-5668914	1.000000e+00	0.000	0	0
Signaling by GPCR	R-HSA-372790	1.000000e+00	0.000	1	0
G alpha (i) signalling events	R-HSA-418594	1.000000e+00	0.000	0	0
Metabolism of proteins	R-HSA-392499	1.000000e+00	-0.000	0	0
Innate Immune System	R-HSA-168249	1.000000e+00	-0.000	1	0
Metabolism of lipids	R-HSA-556833	1.000000e+00	-0.000	0	0
Olfactory Signaling Pathway	R-HSA-381753	1.000000e+00	-0.000	0	0
Metabolism	R-HSA-1430728	1.000000e+00	-0.000	0	0
Transport of small molecules	R-HSA-382551	1.000000e+00	-0.000	0	0
GPCR ligand binding	R-HSA-500792	1.000000e+00	-0.000	0	0
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	1.000000e+00	-0.000	0	0
Biological oxidations	R-HSA-211859	1.000000e+00	-0.000	0	0
Sensory Perception	R-HSA-9709957	1.000000e+00	-0.000	0	0
Metabolism of amino acids and derivatives	R-HSA-71291	1.000000e+00	-0.000	0	0
Advanced glycosylation endproduct receptor signaling	R-HSA-879415	1.000000e+00	0.000	1	1

Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download

name	reactome_id	p	-log10p	ref_path	ref_path_lowest
Chromatin organization	R-HSA-4839726	7.297131e-08	7.137	0	0
Chromatin modifying enzymes	R-HSA-3247509	3.644248e-06	5.438	0	0
Expression of BMAL (ARNTL), CLOCK, and NPAS2	R-HSA-9931509	7.550896e-06	5.122	0	0
Transcriptional regulation by RUNX3	R-HSA-8878159	1.435805e-05	4.843	0	0
Formation of WDR5-containing histone-modifying complexes	R-HSA-9772755	1.326969e-05	4.877	0	0
ATP-dependent chromatin remodelers	R-HSA-9932444	1.774607e-05	4.751	0	0
SWI/SNF chromatin remodelers	R-HSA-9932451	1.774607e-05	4.751	0	0
Formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	2.783119e-05	4.555	0	0
Gene expression (Transcription)	R-HSA-74160	2.763788e-05	4.558	1	0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	R-HSA-9934037	9.059386e-05	4.043	0	0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	R-HSA-9933387	6.712828e-05	4.173	0	0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	R-HSA-5619107	6.712828e-05	4.173	0	0
IP3 and IP4 transport between cytosol and nucleus	R-HSA-1855196	8.521845e-05	4.069	0	0
IP6 and IP7 transport between cytosol and nucleus	R-HSA-1855229	8.521845e-05	4.069	0	0
Vpr-mediated nuclear import of PICs	R-HSA-180910	9.243153e-05	4.034	0	0
Circadian clock	R-HSA-9909396	7.985123e-05	4.098	0	0
Epigenetic regulation of gene expression	R-HSA-212165	7.700326e-05	4.113	0	0
Formation of the embryonic stem cell BAF (esBAF) complex	R-HSA-9933946	7.650232e-05	4.116	0	0
Diseases of signal transduction by growth factor receptors and second messengers	R-HSA-5663202	7.737907e-05	4.111	1	0
Formation of the dystrophin-glycoprotein complex (DGC)	R-HSA-9913351	8.521845e-05	4.069	0	0
NRAGE signals death through JNK	R-HSA-193648	7.087258e-05	4.150	0	0
Rev-mediated nuclear export of HIV RNA	R-HSA-165054	1.136410e-04	3.944	0	0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	R-HSA-8939243	1.341361e-04	3.872	0	0
IPs transport between nucleus and cytosol	R-HSA-1855170	1.341361e-04	3.872	0	0
Transport of the SLBP independent Mature mRNA	R-HSA-159227	1.341361e-04	3.872	0	0
Transport of Mature mRNA Derived from an Intronless Transcript	R-HSA-159231	1.388959e-04	3.857	0	0
Epigenetic regulation by WDR5-containing histone modifying complexes	R-HSA-9917777	1.381194e-04	3.860	0	0
Clathrin-mediated endocytosis	R-HSA-8856828	1.177428e-04	3.929	0	0
Formation of annular gap junctions	R-HSA-196025	1.529648e-04	3.815	0	0
Repression of WNT target genes	R-HSA-4641265	1.689541e-04	3.772	0	0
Transport of the SLBP Dependant Mature mRNA	R-HSA-159230	1.664481e-04	3.779	0	0
Transport of Mature mRNAs Derived from Intronless Transcripts	R-HSA-159234	1.688086e-04	3.773	0	0
Interactions of Vpr with host cellular proteins	R-HSA-176033	1.688086e-04	3.773	0	0
Regulation of Glucokinase by Glucokinase Regulatory Protein	R-HSA-170822	1.664481e-04	3.779	0	0
Interactions of Rev with host cellular proteins	R-HSA-177243	1.688086e-04	3.773	0	0
Transcriptional regulation of granulopoiesis	R-HSA-9616222	1.852384e-04	3.732	0	0
Heme signaling	R-HSA-9707616	1.852384e-04	3.732	0	0
Regulation of TP53 Expression	R-HSA-6804754	2.079866e-04	3.682	0	0
Nuclear import of Rev protein	R-HSA-180746	2.051358e-04	3.688	0	0
Gap junction degradation	R-HSA-190873	2.430265e-04	3.614	0	0
Nuclear Pore Complex (NPC) Disassembly	R-HSA-3301854	2.511756e-04	3.600	0	0
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	2.998323e-04	3.523	0	0
Death Receptor Signaling	R-HSA-73887	3.201827e-04	3.495	0	0
Formation of the polybromo-BAF (pBAF) complex	R-HSA-9933939	3.416691e-04	3.466	0	0
Positive Regulation of CDH1 Gene Transcription	R-HSA-9764790	3.703337e-04	3.431	0	0
TGFBR3 expression	R-HSA-9839394	4.337949e-04	3.363	0	0
p75 NTR receptor-mediated signalling	R-HSA-193704	4.179087e-04	3.379	0	0
Transcriptional regulation by RUNX1	R-HSA-8878171	4.536378e-04	3.343	0	0
Diseases of mitotic cell cycle	R-HSA-9675126	4.554485e-04	3.342	0	0
RUNX3 regulates YAP1-mediated transcription	R-HSA-8951671	4.993038e-04	3.302	0	0
NS1 Mediated Effects on Host Pathways	R-HSA-168276	5.321112e-04	3.274	0	0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	R-HSA-9931510	5.428579e-04	3.265	0	0
Regulation of CDH1 Gene Transcription	R-HSA-9764560	5.639634e-04	3.249	1	0
Regulation of CDH1 Expression and Function	R-HSA-9764265	7.296688e-04	3.137	1	0
Regulation of Expression and Function of Type I Classical Cadherins	R-HSA-9764274	7.296688e-04	3.137	1	0
Signal Transduction	R-HSA-162582	7.116656e-04	3.148	1	0
RUNX3 regulates WNT signaling	R-HSA-8951430	7.983864e-04	3.098	0	0
Binding of TCF/LEF:CTNNB1 to target gene promoters	R-HSA-4411364	7.983864e-04	3.098	0	0
Cellular response to heat stress	R-HSA-3371556	8.102202e-04	3.091	1	0
Transport of Ribonucleoproteins into the Host Nucleus	R-HSA-168271	7.501311e-04	3.125	0	0
Cell death signalling via NRAGE, NRIF and NADE	R-HSA-204998	8.208361e-04	3.086	0	0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex	R-HSA-9931521	8.396773e-04	3.076	0	0
HIV Life Cycle	R-HSA-162587	9.076376e-04	3.042	0	0
Regulation of Homotypic Cell-Cell Adhesion	R-HSA-9759476	8.958672e-04	3.048	1	0
RUNX3 regulates BCL2L11 (BIM) transcription	R-HSA-8952158	9.424467e-04	3.026	0	0
Adipogenesis	R-HSA-9843745	1.006887e-03	2.997	0	0
RET signaling	R-HSA-8853659	1.150477e-03	2.939	0	0
Late Phase of HIV Life Cycle	R-HSA-162599	1.315271e-03	2.881	0	0
Deactivation of the beta-catenin transactivating complex	R-HSA-3769402	1.361125e-03	2.866	0	0
FOXO-mediated transcription of cell death genes	R-HSA-9614657	1.408464e-03	2.851	0	0
Formation of the non-canonical BAF (ncBAF) complex	R-HSA-9933947	1.463732e-03	2.835	0	0
Cell junction organization	R-HSA-446728	1.590489e-03	2.798	1	0
Signaling by NTRK1 (TRKA)	R-HSA-187037	1.620152e-03	2.790	1	0
NEP/NS2 Interacts with the Cellular Export Machinery	R-HSA-168333	1.634442e-03	2.787	0	0
tRNA processing in the nucleus	R-HSA-6784531	1.727817e-03	2.763	0	0
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	1.945162e-03	2.711	0	0
Generic Transcription Pathway	R-HSA-212436	1.927240e-03	2.715	1	0
Formation of the canonical BAF (cBAF) complex	R-HSA-9933937	1.945162e-03	2.711	0	0
Export of Viral Ribonucleoproteins from Nucleus	R-HSA-168274	1.886648e-03	2.724	0	0
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	2.029638e-03	2.693	0	0
Adherens junctions interactions	R-HSA-418990	2.035481e-03	2.691	1	0
Nuclear RNA decay	R-HSA-9930044	2.097495e-03	2.678	0	0
Transport of Mature mRNA derived from an Intron-Containing Transcript	R-HSA-159236	2.250392e-03	2.648	0	0
Transport of Mature Transcript to Cytoplasm	R-HSA-72202	2.252735e-03	2.647	0	0
Regulation of TP53 Activity	R-HSA-5633007	2.381436e-03	2.623	0	0
MITF-M-dependent gene expression	R-HSA-9856651	2.408703e-03	2.618	0	0
Signaling by BRAF and RAF1 fusions	R-HSA-6802952	2.469600e-03	2.607	1	1
PKMTs methylate histone lysines	R-HSA-3214841	2.539223e-03	2.595	0	0
Deubiquitination	R-HSA-5688426	2.686906e-03	2.571	0	0
Regulation of PD-L1(CD274) transcription	R-HSA-9909649	2.768266e-03	2.558	0	0
NOTCH1 Intracellular Domain Regulates Transcription	R-HSA-2122947	2.839019e-03	2.547	0	0
RUNX3 regulates RUNX1-mediated transcription	R-HSA-8951911	3.006508e-03	2.522	0	0
Oncogenic MAPK signaling	R-HSA-6802957	3.047229e-03	2.516	1	0
UCH proteinases	R-HSA-5689603	3.099578e-03	2.509	0	0
Signaling by NOTCH1	R-HSA-1980143	3.099578e-03	2.509	0	0
Cell Cycle, Mitotic	R-HSA-69278	3.123976e-03	2.505	0	0
RNA Polymerase II Transcription	R-HSA-73857	3.462141e-03	2.461	1	0
Cell-Cell communication	R-HSA-1500931	3.602282e-03	2.443	1	0
G alpha (12/13) signalling events	R-HSA-416482	3.799487e-03	2.420	0	0
Activation of HOX genes during differentiation	R-HSA-5619507	4.361044e-03	2.360	0	0
Activation of anterior HOX genes in hindbrain development during early embryogenesis	R-HSA-5617472	4.361044e-03	2.360	0	0
Viral Messenger RNA Synthesis	R-HSA-168325	4.266169e-03	2.370	0	0
Signaling by NTRKs	R-HSA-166520	4.288256e-03	2.368	1	0
Aberrant regulation of mitotic cell cycle due to RB1 defects	R-HSA-9687139	4.531494e-03	2.344	0	0
Activation of RAC1	R-HSA-428540	4.556993e-03	2.341	0	0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters	R-HSA-9931512	4.556993e-03	2.341	0	0
Signaling by Hippo	R-HSA-2028269	5.134020e-03	2.290	0	0
Loss of MECP2 binding ability to 5mC-DNA	R-HSA-9022538	5.575722e-03	2.254	0	0
Signaling downstream of RAS mutants	R-HSA-9649948	5.704842e-03	2.244	1	1
Paradoxical activation of RAF signaling by kinase inactive BRAF	R-HSA-6802955	5.704842e-03	2.244	1	1
Signaling by moderate kinase activity BRAF mutants	R-HSA-6802946	5.704842e-03	2.244	1	1
Transcriptional regulation by small RNAs	R-HSA-5578749	5.239520e-03	2.281	0	0
Signaling by RAS mutants	R-HSA-6802949	5.704842e-03	2.244	1	0
TCF dependent signaling in response to WNT	R-HSA-201681	5.704447e-03	2.244	0	0
Activation of PUMA and translocation to mitochondria	R-HSA-139915	5.835659e-03	2.234	0	0
RUNX3 regulates NOTCH signaling	R-HSA-8941856	5.945230e-03	2.226	0	0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	R-HSA-9818564	5.966166e-03	2.224	0	0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	R-HSA-9841922	5.966166e-03	2.224	0	0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes	R-HSA-9851695	5.966166e-03	2.224	0	0
Transcriptional Regulation by E2F6	R-HSA-8953750	6.051902e-03	2.218	0	0
Cell Cycle	R-HSA-1640170	6.312642e-03	2.200	0	0
Regulation of MECP2 expression and activity	R-HSA-9022692	7.180143e-03	2.144	0	0
NGF-stimulated transcription	R-HSA-9031628	7.261681e-03	2.139	0	0
Non-integrin membrane-ECM interactions	R-HSA-3000171	7.011637e-03	2.154	0	0
Nuclear Envelope Breakdown	R-HSA-2980766	7.344119e-03	2.134	0	0
Regulation of HSF1-mediated heat shock response	R-HSA-3371453	7.582231e-03	2.120	1	1
NFE2L2 regulating tumorigenic genes	R-HSA-9818030	7.606935e-03	2.119	0	0
Formation of axial mesoderm	R-HSA-9796292	7.606935e-03	2.119	0	0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	R-HSA-9659787	7.606935e-03	2.119	0	0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	R-HSA-9661069	7.606935e-03	2.119	0	0
Mitotic Prophase	R-HSA-68875	8.053721e-03	2.094	0	0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	R-HSA-8939246	8.089574e-03	2.092	0	0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence	R-HSA-9825895	8.089574e-03	2.092	0	0
Alternative Lengthening of Telomeres (ALT)	R-HSA-9006821	9.012805e-03	2.045	0	0
Diseases of Telomere Maintenance	R-HSA-9673013	9.012805e-03	2.045	0	0
Defective Inhibition of DNA Recombination at Telomere	R-HSA-9670621	9.012805e-03	2.045	0	0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations	R-HSA-9670615	9.012805e-03	2.045	0	0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	R-HSA-9670613	9.012805e-03	2.045	0	0
Loss of MECP2 binding ability to 5hmC-DNA	R-HSA-9022534	9.012805e-03	2.045	0	0
DNA Damage Recognition in GG-NER	R-HSA-5696394	8.281079e-03	2.082	0	0
Signaling by RAF1 mutants	R-HSA-9656223	8.910654e-03	2.050	1	1
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	R-HSA-8936459	8.809250e-03	2.055	0	0
Cellular Senescence	R-HSA-2559583	8.931197e-03	2.049	1	0
Inositol phosphate metabolism	R-HSA-1483249	8.158762e-03	2.088	0	0
Metabolism of non-coding RNA	R-HSA-194441	9.062648e-03	2.043	0	0
snRNP Assembly	R-HSA-191859	9.062648e-03	2.043	0	0
Regulation of beta-cell development	R-HSA-186712	9.062648e-03	2.043	0	0
RUNX2 regulates genes involved in differentiation of myeloid cells	R-HSA-8941333	9.150342e-03	2.039	0	0
Nuclear Receptor transcription pathway	R-HSA-383280	9.228234e-03	2.035	0	0
TP53 Regulates Transcription of Death Receptors and Ligands	R-HSA-6803211	9.566967e-03	2.019	0	0
Inactivation of CDC42 and RAC1	R-HSA-428543	1.084947e-02	1.965	0	0
Caspase-mediated cleavage of cytoskeletal proteins	R-HSA-264870	1.084947e-02	1.965	0	0
HIV Infection	R-HSA-162906	1.094160e-02	1.961	0	0
NOTCH4 Intracellular Domain Regulates Transcription	R-HSA-9013695	1.109194e-02	1.955	0	0
Cell-extracellular matrix interactions	R-HSA-446353	1.184888e-02	1.926	0	0
Cell-cell junction organization	R-HSA-421270	1.171745e-02	1.931	1	0
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	1.273082e-02	1.895	1	0
HATs acetylate histones	R-HSA-3214847	1.296798e-02	1.887	0	0
Regulation of gene expression in beta cells	R-HSA-210745	1.307153e-02	1.884	0	0
IRS activation	R-HSA-74713	1.380241e-02	1.860	0	0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	R-HSA-3134973	1.380241e-02	1.860	0	0
Signaling by high-kinase activity BRAF mutants	R-HSA-6802948	1.397962e-02	1.855	1	1
Signal attenuation	R-HSA-74749	1.415305e-02	1.849	1	1
Regulation of lipid metabolism by PPARalpha	R-HSA-400206	1.446582e-02	1.840	0	0
Signaling by TGFBR3	R-HSA-9839373	1.580076e-02	1.801	0	0
Developmental Biology	R-HSA-1266738	1.616206e-02	1.792	1	0
MITF-M-regulated melanocyte development	R-HSA-9730414	1.645579e-02	1.784	1	0
ISG15 antiviral mechanism	R-HSA-1169408	1.645776e-02	1.784	1	1
Signaling by EGFR	R-HSA-177929	1.695515e-02	1.771	0	0
Disorders of Developmental Biology	R-HSA-9675151	1.746447e-02	1.758	0	0
Recycling pathway of L1	R-HSA-437239	1.755007e-02	1.756	0	0
Interleukin receptor SHC signaling	R-HSA-912526	1.796516e-02	1.746	0	0
Response of EIF2AK1 (HRI) to heme deficiency	R-HSA-9648895	1.796516e-02	1.746	0	0
RUNX1 regulates expression of components of tight junctions	R-HSA-8935964	1.957465e-02	1.708	0	0
Loss of MECP2 binding ability to the NCoR/SMRT complex	R-HSA-9022537	1.957465e-02	1.708	0	0
Regulation of TP53 Activity through Phosphorylation	R-HSA-6804756	1.925332e-02	1.715	0	0
Transcriptional Regulation by TP53	R-HSA-3700989	1.998341e-02	1.699	0	0
SARS-CoV-2 activates/modulates innate and adaptive immune responses	R-HSA-9705671	2.116978e-02	1.674	0	0
Transcriptional Regulation by VENTX	R-HSA-8853884	2.210924e-02	1.655	0	0
PPARA activates gene expression	R-HSA-1989781	2.354878e-02	1.628	0	0
HDMs demethylate histones	R-HSA-3214842	2.389725e-02	1.622	0	0
Regulation of PTEN gene transcription	R-HSA-8943724	2.439811e-02	1.613	1	1
Negative Regulation of CDH1 Gene Transcription	R-HSA-9764725	2.439811e-02	1.613	1	1
MAP2K and MAPK activation	R-HSA-5674135	2.457457e-02	1.610	1	1
Signaling by FGFR1 in disease	R-HSA-5655302	2.457457e-02	1.610	0	0
Polo-like kinase mediated events	R-HSA-156711	2.460698e-02	1.609	0	0
Signaling by cytosolic FGFR1 fusion mutants	R-HSA-1839117	2.460698e-02	1.609	0	0
Mitochondrial biogenesis	R-HSA-1592230	2.604220e-02	1.584	0	0
Regulation of NFE2L2 gene expression	R-HSA-9818749	2.648509e-02	1.577	0	0
Interleukin-3, Interleukin-5 and GM-CSF signaling	R-HSA-512988	2.722601e-02	1.565	0	0
Postmitotic nuclear pore complex (NPC) reformation	R-HSA-9615933	2.730309e-02	1.564	0	0
RUNX3 regulates p14-ARF	R-HSA-8951936	2.761401e-02	1.559	0	0
Loss of function of MECP2 in Rett syndrome	R-HSA-9005891	2.761401e-02	1.559	0	0
Pervasive developmental disorders	R-HSA-9005895	2.761401e-02	1.559	0	0
Disorders of Nervous System Development	R-HSA-9697154	2.761401e-02	1.559	0	0
Interleukin-15 signaling	R-HSA-8983432	2.761401e-02	1.559	0	0
Signaling by LTK	R-HSA-9842663	2.761401e-02	1.559	0	0
Mitotic Spindle Checkpoint	R-HSA-69618	2.841021e-02	1.547	0	0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	R-HSA-9029558	3.335058e-02	1.477	0	0
Transcription of E2F targets under negative control by DREAM complex	R-HSA-1362277	3.339602e-02	1.476	0	0
Regulation of TP53 Activity through Association with Co-factors	R-HSA-6804759	3.335058e-02	1.477	0	0
Oxidative Stress Induced Senescence	R-HSA-2559580	3.223217e-02	1.492	1	1
Oncogene Induced Senescence	R-HSA-2559585	3.110445e-02	1.507	1	1
Signaling by WNT	R-HSA-195721	3.079761e-02	1.511	0	0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	R-HSA-446343	3.288277e-02	1.483	0	0
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	R-HSA-2559584	3.335058e-02	1.477	0	0
RNA Polymerase II Pre-transcription Events	R-HSA-674695	3.343781e-02	1.476	0	0
SOS-mediated signalling	R-HSA-112412	3.453118e-02	1.462	0	0
G1/S-Specific Transcription	R-HSA-69205	3.460297e-02	1.461	0	0
Membrane Trafficking	R-HSA-199991	3.577357e-02	1.446	0	0
Signaling by Receptor Tyrosine Kinases	R-HSA-9006934	3.842046e-02	1.415	1	0
Zygotic genome activation (ZGA)	R-HSA-9819196	3.843541e-02	1.415	0	0
Host Interactions of HIV factors	R-HSA-162909	3.869897e-02	1.412	0	0
Developmental Lineage of Mammary Gland Myoepithelial Cells	R-HSA-9927432	3.939083e-02	1.405	0	0
Retrograde neurotrophin signalling	R-HSA-177504	3.973051e-02	1.401	0	0
Type I hemidesmosome assembly	R-HSA-446107	4.369337e-02	1.360	0	0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	R-HSA-111453	4.369337e-02	1.360	0	0
MET receptor recycling	R-HSA-8875656	4.369337e-02	1.360	0	0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	R-HSA-9825892	4.391464e-02	1.357	0	0
NOTCH3 Intracellular Domain Regulates Transcription	R-HSA-9013508	4.406761e-02	1.356	0	0
Activation of BH3-only proteins	R-HSA-114452	4.406761e-02	1.356	0	0
MET interacts with TNS proteins	R-HSA-8875513	4.909032e-02	1.309	0	0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	R-HSA-450513	4.675671e-02	1.330	0	0
Notch-HLH transcription pathway	R-HSA-350054	4.983824e-02	1.302	0	0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	R-HSA-73779	5.116161e-02	1.291	0	0
Regulation of cholesterol biosynthesis by SREBP (SREBF)	R-HSA-1655829	4.736581e-02	1.325	0	0
Transcriptional Regulation by MECP2	R-HSA-8986944	5.442200e-02	1.264	0	0
Degradation of beta-catenin by the destruction complex	R-HSA-195253	5.272133e-02	1.278	0	0
Signaling by WNT in cancer	R-HSA-4791275	5.442310e-02	1.264	0	0
Mitotic G1 phase and G1/S transition	R-HSA-453279	4.608594e-02	1.336	0	0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	R-HSA-6803205	4.983824e-02	1.302	0	0
Interleukin-2 family signaling	R-HSA-451927	5.116161e-02	1.291	0	0
Signaling by NOTCH	R-HSA-157118	5.051791e-02	1.297	0	0
Signaling by MET	R-HSA-6806834	5.056292e-02	1.296	0	0
STAT3 nuclear events downstream of ALK signaling	R-HSA-9701898	4.675671e-02	1.330	0	0
Gastrulation	R-HSA-9758941	5.294086e-02	1.276	0	0
Signaling by ALK	R-HSA-201556	4.662803e-02	1.331	0	0
Signaling by ALK fusions and activated point mutants	R-HSA-9725370	4.592179e-02	1.338	1	0
Signaling by ALK in cancer	R-HSA-9700206	4.592179e-02	1.338	1	0
Regulation of CDH11 gene transcription	R-HSA-9762293	5.393827e-02	1.268	0	0
Apoptotic cleavage of cellular proteins	R-HSA-111465	5.442310e-02	1.264	0	0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	R-HSA-1362300	5.442703e-02	1.264	0	0
Aberrant regulation of mitotic exit in cancer due to RB1 defects	R-HSA-9687136	5.442703e-02	1.264	0	0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	5.442703e-02	1.264	0	0
Glycolysis	R-HSA-70171	5.444875e-02	1.264	0	0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	R-HSA-2894858	5.454009e-02	1.263	0	0
Constitutive Signaling by NOTCH1 PEST Domain Mutants	R-HSA-2644606	5.454009e-02	1.263	0	0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	R-HSA-2894862	5.454009e-02	1.263	0	0
Signaling by NOTCH1 PEST Domain Mutants in Cancer	R-HSA-2644602	5.454009e-02	1.263	0	0
Signaling by NOTCH1 in Cancer	R-HSA-2644603	5.454009e-02	1.263	0	0
FGFR1 mutant receptor activation	R-HSA-1839124	6.010769e-02	1.221	0	0
Regulation of Expression and Function of Type II Classical Cadherins	R-HSA-9764260	6.010769e-02	1.221	0	0
Synthesis of IP3 and IP4 in the cytosol	R-HSA-1855204	6.010769e-02	1.221	0	0
RNA Polymerase II HIV Promoter Escape	R-HSA-167162	6.103647e-02	1.214	0	0
HIV Transcription Initiation	R-HSA-167161	6.103647e-02	1.214	0	0
RNA Polymerase II Transcription Initiation	R-HSA-75953	6.103647e-02	1.214	0	0
TRAF3-dependent IRF activation pathway	R-HSA-918233	6.273464e-02	1.202	0	0
MECP2 regulates transcription of neuronal ligands	R-HSA-9022702	6.522132e-02	1.186	0	0
MET activates RAP1 and RAC1	R-HSA-8875555	6.522132e-02	1.186	0	0
PI3K/AKT activation	R-HSA-198203	6.522132e-02	1.186	0	0
Activation of gene expression by SREBF (SREBP)	R-HSA-2426168	6.737011e-02	1.172	0	0
MECP2 regulates transcription of genes involved in GABA signaling	R-HSA-9022927	6.755993e-02	1.170	0	0
Regulation of gap junction activity	R-HSA-191650	6.755993e-02	1.170	0	0
NFE2L2 regulating ER-stress associated genes	R-HSA-9818035	6.755993e-02	1.170	0	0
GRB7 events in ERBB2 signaling	R-HSA-1306955	6.755993e-02	1.170	0	0
Activation of NOXA and translocation to mitochondria	R-HSA-111448	6.755993e-02	1.170	0	0
SARS-CoV-2 targets PDZ proteins in cell-cell junction	R-HSA-9705677	6.755993e-02	1.170	0	0
Cargo recognition for clathrin-mediated endocytosis	R-HSA-8856825	6.758986e-02	1.170	0	0
Loss of Function of TP53 in Cancer	R-HSA-9723907	6.794341e-02	1.168	0	0
Defective translocation of RB1 mutants to the nucleus	R-HSA-9661070	6.794341e-02	1.168	0	0
APC truncation mutants are not K63 polyubiquitinated	R-HSA-5467333	6.794341e-02	1.168	0	0
Loss of function of TP53 in cancer due to loss of tetramerization ability	R-HSA-9723905	6.794341e-02	1.168	0	0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK	R-HSA-9931529	8.790999e-02	1.056	0	0
RUNX2 regulates chondrocyte maturation	R-HSA-8941284	8.790999e-02	1.056	0	0
NFE2L2 regulating inflammation associated genes	R-HSA-9818026	8.790999e-02	1.056	0	0
G2 Phase	R-HSA-68911	8.790999e-02	1.056	0	0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	R-HSA-9673768	8.790999e-02	1.056	0	0
Loss of phosphorylation of MECP2 at T308	R-HSA-9022535	8.790999e-02	1.056	0	0
MECP2 regulates neuronal receptors and channels	R-HSA-9022699	7.798768e-02	1.108	0	0
Regulation of RUNX1 Expression and Activity	R-HSA-8934593	7.798768e-02	1.108	0	0
BMAL1:CLOCK,NPAS2 activates circadian expression	R-HSA-1368108	7.249591e-02	1.140	0	0
RAF activation	R-HSA-5673000	7.249591e-02	1.140	0	0
RNA Polymerase II Promoter Escape	R-HSA-73776	7.200021e-02	1.143	0	0
RNA Polymerase II Transcription Initiation And Promoter Clearance	R-HSA-76042	8.405644e-02	1.075	0	0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	R-HSA-141444	7.279460e-02	1.138	0	0
Amplification of signal from the kinetochores	R-HSA-141424	7.279460e-02	1.138	0	0
TP53 Regulates Transcription of DNA Repair Genes	R-HSA-6796648	8.691661e-02	1.061	0	0
Signaling by FLT3 fusion proteins	R-HSA-9703465	7.798768e-02	1.108	0	0
S Phase	R-HSA-69242	8.374211e-02	1.077	0	0
Serotonin Neurotransmitter Release Cycle	R-HSA-181429	8.121334e-02	1.090	0	0
TNF signaling	R-HSA-75893	8.642447e-02	1.063	0	0
Nervous system development	R-HSA-9675108	8.099511e-02	1.092	1	0
Tie2 Signaling	R-HSA-210993	8.121334e-02	1.090	0	0
Myogenesis	R-HSA-525793	7.798768e-02	1.108	0	0
Regulation of MITF-M-dependent genes involved in pigmentation	R-HSA-9824585	8.405644e-02	1.075	0	0
Nephron development	R-HSA-9831926	8.121334e-02	1.090	0	0
Specification of primordial germ cells	R-HSA-9827857	7.166842e-02	1.145	0	0
Gene Silencing by RNA	R-HSA-211000	8.266194e-02	1.083	0	0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	R-HSA-9926550	8.121334e-02	1.090	0	0
Apoptotic execution phase	R-HSA-75153	9.049204e-02	1.043	0	0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis	R-HSA-9623433	9.068201e-02	1.042	0	0
Inhibition of replication initiation of damaged DNA by RB1/E2F1	R-HSA-113501	9.068201e-02	1.042	0	0
Cell Cycle Checkpoints	R-HSA-69620	9.176384e-02	1.037	0	0
Regulation of CDH1 Function	R-HSA-9764561	9.233174e-02	1.035	0	0
Transcription of the HIV genome	R-HSA-167172	9.264250e-02	1.033	0	0
Sensory processing of sound by inner hair cells of the cochlea	R-HSA-9662360	9.264250e-02	1.033	0	0
FOXO-mediated transcription	R-HSA-9614085	9.331830e-02	1.030	0	0
MAPK family signaling cascades	R-HSA-5683057	9.522456e-02	1.021	1	0
Regulation of CDH11 Expression and Function	R-HSA-9759475	1.036611e-01	0.984	0	0
Nuclear events stimulated by ALK signaling in cancer	R-HSA-9725371	1.041674e-01	0.982	1	1
NOTCH2 intracellular domain regulates transcription	R-HSA-2197563	1.047347e-01	0.980	0	0
Constitutive Signaling by Overexpressed ERBB2	R-HSA-9634285	1.047347e-01	0.980	0	0
Regulation of FOXO transcriptional activity by acetylation	R-HSA-9617629	1.047347e-01	0.980	0	0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex	R-HSA-9931530	1.047347e-01	0.980	0	0
RUNX3 regulates CDKN1A transcription	R-HSA-8941855	1.098002e-01	0.959	0	0
Epithelial-Mesenchymal Transition (EMT) during gastrulation	R-HSA-9758919	1.098002e-01	0.959	0	0
SLIT2:ROBO1 increases RHOA activity	R-HSA-8985586	1.098002e-01	0.959	0	0
Signaling by RNF43 mutants	R-HSA-5340588	1.098002e-01	0.959	0	0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	R-HSA-446388	1.098002e-01	0.959	0	0
Gap junction trafficking and regulation	R-HSA-157858	1.114007e-01	0.953	0	0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)	R-HSA-9845323	1.114021e-01	0.953	0	0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	R-HSA-450321	1.133146e-01	0.946	0	0
Regulation of MITF-M-dependent genes involved in apoptosis	R-HSA-9824594	1.133146e-01	0.946	0	0
Regulation of PAK-2p34 activity by PS-GAP/RHG10	R-HSA-211728	1.312743e-01	0.882	0	0
Defective DNA double strand break response due to BRCA1 loss of function	R-HSA-9663199	1.312743e-01	0.882	0	0
Defective DNA double strand break response due to BARD1 loss of function	R-HSA-9699150	1.312743e-01	0.882	0	0
Signaling by LTK in cancer	R-HSA-9842640	1.329277e-01	0.876	1	1
G2/M DNA replication checkpoint	R-HSA-69478	1.329277e-01	0.876	0	0
Erythropoietin activates RAS	R-HSA-9027284	1.513599e-01	0.820	0	0
Processive synthesis on the lagging strand	R-HSA-69183	1.513599e-01	0.820	0	0
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	1.170196e-01	0.932	0	0
Integrin signaling	R-HSA-354192	1.434806e-01	0.843	0	0
Global Genome Nucleotide Excision Repair (GG-NER)	R-HSA-5696399	1.197027e-01	0.922	0	0
G0 and Early G1	R-HSA-1538133	1.329675e-01	0.876	0	0
DNA strand elongation	R-HSA-69190	1.329675e-01	0.876	0	0
G1/S Transition	R-HSA-69206	1.239126e-01	0.907	0	0
PTEN Regulation	R-HSA-6807070	1.431570e-01	0.844	1	0
Estrogen-dependent gene expression	R-HSA-9018519	1.283626e-01	0.892	0	0
M Phase	R-HSA-68886	1.230014e-01	0.910	0	0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	R-HSA-9634638	1.500850e-01	0.824	1	1
Regulation of TP53 Activity through Acetylation	R-HSA-6804758	1.434806e-01	0.843	0	0
Negative regulation of MAPK pathway	R-HSA-5675221	1.352359e-01	0.869	1	1
Downstream signal transduction	R-HSA-186763	1.228164e-01	0.911	0	0
FLT3 Signaling	R-HSA-9607240	1.262965e-01	0.899	0	0
Signaling by PDGFR in disease	R-HSA-9671555	1.250900e-01	0.903	0	0
Signaling by FGFR in disease	R-HSA-1226099	1.293548e-01	0.888	0	0
Dopamine Neurotransmitter Release Cycle	R-HSA-212676	1.373568e-01	0.862	0	0
MAP kinase activation	R-HSA-450294	1.182008e-01	0.927	1	0
Axon guidance	R-HSA-422475	1.413417e-01	0.850	1	0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	R-HSA-450385	1.513599e-01	0.820	0	0
Smooth Muscle Contraction	R-HSA-445355	1.428653e-01	0.845	0	0
L1CAM interactions	R-HSA-373760	1.342808e-01	0.872	1	0
VEGFA-VEGFR2 Pathway	R-HSA-4420097	1.289771e-01	0.889	0	0
Signaling by TGFB family members	R-HSA-9006936	1.309840e-01	0.883	1	0
Glucose metabolism	R-HSA-70326	1.397034e-01	0.855	0	0
Striated Muscle Contraction	R-HSA-390522	1.543395e-01	0.812	0	0
EGR2 and SOX10-mediated initiation of Schwann cell myelination	R-HSA-9619665	1.543395e-01	0.812	0	0
Cellular responses to stress	R-HSA-2262752	1.549871e-01	0.810	1	0
MECP2 regulates transcription factors	R-HSA-9022707	1.570237e-01	0.804	0	0
NOSTRIN mediated eNOS trafficking	R-HSA-203641	1.570237e-01	0.804	0	0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose	R-HSA-9031528	1.570237e-01	0.804	0	0
Cohesin Loading onto Chromatin	R-HSA-2470946	1.570237e-01	0.804	0	0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake	R-HSA-9031525	1.570237e-01	0.804	0	0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	R-HSA-2892245	1.570237e-01	0.804	0	0
Signaling by NOTCH3	R-HSA-9012852	1.600339e-01	0.796	0	0
Defective MMADHC causes MMAHCD	R-HSA-3359473	1.903056e-01	0.721	0	0
XAV939 stabilizes AXIN	R-HSA-5545619	1.903056e-01	0.721	0	0
Signaling by TCF7L2 mutants	R-HSA-5339700	1.903056e-01	0.721	0	0
Drug resistance in ERBB2 KD mutants	R-HSA-9665230	2.453289e-01	0.610	0	0
Drug-mediated inhibition of ERBB2 signaling	R-HSA-9652282	2.453289e-01	0.610	0	0
Regulation of cortical dendrite branching	R-HSA-8985801	2.453289e-01	0.610	0	0
Resistance of ERBB2 KD mutants to neratinib	R-HSA-9665246	2.453289e-01	0.610	0	0
Resistance of ERBB2 KD mutants to afatinib	R-HSA-9665249	2.453289e-01	0.610	0	0
Resistance of ERBB2 KD mutants to lapatinib	R-HSA-9665251	2.453289e-01	0.610	0	0
Resistance of ERBB2 KD mutants to sapitinib	R-HSA-9665244	2.453289e-01	0.610	0	0
Drug resistance in ERBB2 TMD/JMD mutants	R-HSA-9665737	2.453289e-01	0.610	0	0
Resistance of ERBB2 KD mutants to AEE788	R-HSA-9665250	2.453289e-01	0.610	0	0
Resistance of ERBB2 KD mutants to osimertinib	R-HSA-9665247	2.453289e-01	0.610	0	0
Resistance of ERBB2 KD mutants to tesevatinib	R-HSA-9665245	2.453289e-01	0.610	0	0
Resistance of ERBB2 KD mutants to trastuzumab	R-HSA-9665233	2.453289e-01	0.610	0	0
Glycogen storage disease type XV (GYG1)	R-HSA-3814836	2.453289e-01	0.610	0	0
Glycogen storage disease type 0 (muscle GYS1)	R-HSA-3828062	2.453289e-01	0.610	0	0
Signaling by plasma membrane FGFR1 fusions	R-HSA-8853336	2.966161e-01	0.528	0	0
Activation of BIM and translocation to mitochondria	R-HSA-111446	2.966161e-01	0.528	0	0
Defective MMACHC causes MAHCC	R-HSA-3359474	2.966161e-01	0.528	0	0
Loss of Function of KMT2D in Kabuki Syndrome	R-HSA-9944971	2.966161e-01	0.528	0	0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome	R-HSA-9944997	2.966161e-01	0.528	0	0
MET activates PTPN11	R-HSA-8865999	2.966161e-01	0.528	0	0
NFE2L2 regulating MDR associated enzymes	R-HSA-9818032	2.071969e-01	0.684	0	0
HCN channels	R-HSA-1296061	3.444207e-01	0.463	0	0
PLCG1 events in ERBB2 signaling	R-HSA-1251932	3.444207e-01	0.463	0	0
Drug-mediated inhibition of CDK4/CDK6 activity	R-HSA-9754119	3.444207e-01	0.463	0	0
Signaling by LRP5 mutants	R-HSA-5339717	3.444207e-01	0.463	0	0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	R-HSA-69200	3.444207e-01	0.463	0	0
Phosphorylation of the APC/C	R-HSA-176412	1.681534e-01	0.774	0	0
GRB2:SOS provides linkage to MAPK signaling for Integrins	R-HSA-354194	1.681534e-01	0.774	0	0
RUNX2 regulates genes involved in cell migration	R-HSA-8941332	2.587332e-01	0.587	0	0
Signaling by APC mutants	R-HSA-4839744	2.587332e-01	0.587	0	0
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	2.587332e-01	0.587	0	0
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	2.587332e-01	0.587	0	0
Truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	2.587332e-01	0.587	0	0
RUNX1 regulates transcription of genes involved in interleukin signaling	R-HSA-8939247	3.889790e-01	0.410	0	0
RUNX1 regulates transcription of genes involved in BCR signaling	R-HSA-8939245	3.889790e-01	0.410	0	0
NOSIP mediated eNOS trafficking	R-HSA-203754	3.889790e-01	0.410	0	0
p130Cas linkage to MAPK signaling for integrins	R-HSA-372708	2.031933e-01	0.692	0	0
Condensation of Prometaphase Chromosomes	R-HSA-2514853	2.846185e-01	0.546	0	0
Signaling by GSK3beta mutants	R-HSA-5339716	2.846185e-01	0.546	0	0
Signaling by ERBB2 ECD mutants	R-HSA-9665348	2.213027e-01	0.655	0	0
APC/C:Cdc20 mediated degradation of Cyclin B	R-HSA-174048	2.397170e-01	0.620	0	0
Abortive elongation of HIV-1 transcript in the absence of Tat	R-HSA-167242	2.397170e-01	0.620	0	0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	R-HSA-9027276	3.104113e-01	0.508	0	0
Leading Strand Synthesis	R-HSA-69109	3.104113e-01	0.508	0	0
Polymerase switching	R-HSA-69091	3.104113e-01	0.508	0	0
Signaling by CTNNB1 phospho-site mutants	R-HSA-4839743	3.104113e-01	0.508	0	0
CTNNB1 S45 mutants aren't phosphorylated	R-HSA-5358751	3.104113e-01	0.508	0	0
CTNNB1 S33 mutants aren't phosphorylated	R-HSA-5358747	3.104113e-01	0.508	0	0
CTNNB1 S37 mutants aren't phosphorylated	R-HSA-5358749	3.104113e-01	0.508	0	0
CTNNB1 T41 mutants aren't phosphorylated	R-HSA-5358752	3.104113e-01	0.508	0	0
Nef Mediated CD8 Down-regulation	R-HSA-182218	4.305113e-01	0.366	0	0
Noncanonical activation of NOTCH3	R-HSA-9017802	4.305113e-01	0.366	0	0
Signaling by MAPK mutants	R-HSA-9652817	4.305113e-01	0.366	0	0
RUNX2 regulates osteoblast differentiation	R-HSA-8940973	2.195194e-01	0.659	1	1
RUNX2 regulates bone development	R-HSA-8941326	1.888120e-01	0.724	1	0
Lagging Strand Synthesis	R-HSA-69186	2.772130e-01	0.557	0	0
APC-Cdc20 mediated degradation of Nek2A	R-HSA-179409	2.772130e-01	0.557	0	0
Signaling by Erythropoietin	R-HSA-9006335	2.343324e-01	0.630	0	0
Impaired BRCA2 binding to RAD51	R-HSA-9709570	2.343324e-01	0.630	0	0
Signaling by ERBB2 in Cancer	R-HSA-1227990	2.493762e-01	0.603	0	0
Activation of the pre-replicative complex	R-HSA-68962	2.493762e-01	0.603	0	0
Regulation of CDH1 mRNA translation by microRNAs	R-HSA-9764562	3.613067e-01	0.442	0	0
Removal of the Flap Intermediate	R-HSA-69166	3.613067e-01	0.442	0	0
RUNX1 regulates transcription of genes involved in WNT signaling	R-HSA-8939256	4.692229e-01	0.329	0	0
STAT5 Activation	R-HSA-9645135	4.692229e-01	0.329	0	0
Erythropoietin activates STAT5	R-HSA-9027283	4.692229e-01	0.329	0	0
Autointegration results in viral DNA circles	R-HSA-177539	4.692229e-01	0.329	0	0
IRF3-mediated induction of type I IFN	R-HSA-3270619	3.862388e-01	0.413	0	0
Beta-catenin phosphorylation cascade	R-HSA-196299	3.862388e-01	0.413	0	0
HSF1-dependent transactivation	R-HSA-3371571	2.386750e-01	0.622	0	0
Processing of Intronless Pre-mRNAs	R-HSA-77595	4.347381e-01	0.362	0	0
GRB2 events in ERBB2 signaling	R-HSA-1963640	4.347381e-01	0.362	0	0
RNA polymerase II transcribes snRNA genes	R-HSA-6807505	2.302735e-01	0.638	0	0
Condensation of Prophase Chromosomes	R-HSA-2299718	3.319772e-01	0.479	0	0
Tat-mediated HIV elongation arrest and recovery	R-HSA-167243	4.098384e-01	0.387	0	0
Pausing and recovery of Tat-mediated HIV elongation	R-HSA-167238	4.098384e-01	0.387	0	0
PI3K events in ERBB2 signaling	R-HSA-1963642	4.582032e-01	0.339	0	0
Formation of the HIV-1 Early Elongation Complex	R-HSA-167158	4.283670e-01	0.368	0	0
HIV elongation arrest and recovery	R-HSA-167287	4.283670e-01	0.368	0	0
Formation of the Early Elongation Complex	R-HSA-113418	4.283670e-01	0.368	0	0
Activation of AMPK downstream of NMDARs	R-HSA-9619483	4.283670e-01	0.368	0	0
Pausing and recovery of HIV elongation	R-HSA-167290	4.283670e-01	0.368	0	0
Regulation of RUNX2 expression and activity	R-HSA-8939902	3.585264e-01	0.445	0	0
GAB1 signalosome	R-HSA-180292	4.810923e-01	0.318	0	0
PCNA-Dependent Long Patch Base Excision Repair	R-HSA-5651801	4.810923e-01	0.318	0	0
Signaling by ERBB2 KD Mutants	R-HSA-9664565	4.466840e-01	0.350	0	0
Formation of RNA Pol II elongation complex	R-HSA-112382	4.144454e-01	0.383	0	0
NR1H2 and NR1H3-mediated signaling	R-HSA-9024446	3.905665e-01	0.408	0	0
RNA Polymerase II Transcription Elongation	R-HSA-75955	4.281093e-01	0.368	0	0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	R-HSA-174178	4.281093e-01	0.368	0	0
Transcriptional regulation by RUNX2	R-HSA-8878166	4.598212e-01	0.337	1	0
Nucleotide Excision Repair	R-HSA-5696398	2.071211e-01	0.684	0	0
Processing of DNA double-strand break ends	R-HSA-5693607	4.358180e-01	0.361	0	0
HCMV Early Events	R-HSA-9609690	1.882299e-01	0.725	0	0
VxPx cargo-targeting to cilium	R-HSA-5620916	2.583738e-01	0.588	0	0
Signaling by ERBB2	R-HSA-1227986	3.461972e-01	0.461	0	0
p75NTR recruits signalling complexes	R-HSA-209543	3.104113e-01	0.508	0	0
Cyclin D associated events in G1	R-HSA-69231	1.637484e-01	0.786	0	0
G1 Phase	R-HSA-69236	1.637484e-01	0.786	0	0
Disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	2.049705e-01	0.688	0	0
Golgi Associated Vesicle Biogenesis	R-HSA-432722	2.617740e-01	0.582	0	0
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	4.647613e-01	0.333	0	0
TRAF6 mediated IRF7 activation	R-HSA-933541	3.742544e-01	0.427	0	0
Activation of RAC1 downstream of NMDARs	R-HSA-9619229	2.071969e-01	0.684	0	0
SHC1 events in ERBB2 signaling	R-HSA-1250196	4.647613e-01	0.333	0	0
FOXO-mediated transcription of cell cycle genes	R-HSA-9617828	2.961781e-01	0.528	0	0
Platelet Aggregation (Plug Formation)	R-HSA-76009	3.183102e-01	0.497	0	0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	R-HSA-6803204	2.049705e-01	0.688	0	0
activated TAK1 mediates p38 MAPK activation	R-HSA-450302	2.961781e-01	0.528	0	0
HDACs deacetylate histones	R-HSA-3214815	4.552293e-01	0.342	0	0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	R-HSA-5693565	3.339079e-01	0.476	0	0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	R-HSA-6804115	3.152153e-01	0.501	0	0
Downregulation of ERBB2 signaling	R-HSA-8863795	4.647613e-01	0.333	0	0
TP53 Regulates Transcription of Cell Death Genes	R-HSA-5633008	2.338787e-01	0.631	0	0
Diseases of DNA Double-Strand Break Repair	R-HSA-9675136	3.269319e-01	0.486	0	0
Synthesis of DNA	R-HSA-69239	3.302720e-01	0.481	0	0
p75NTR signals via NF-kB	R-HSA-193639	3.862388e-01	0.413	0	0
Regulation of endogenous retroelements	R-HSA-9842860	1.785356e-01	0.748	0	0
TFAP2 (AP-2) family regulates transcription of cell cycle factors	R-HSA-8866911	3.444207e-01	0.463	0	0
E2F mediated regulation of DNA replication	R-HSA-113510	2.397170e-01	0.620	0	0
VLDLR internalisation and degradation	R-HSA-8866427	3.104113e-01	0.508	0	0
Ligand-receptor interactions	R-HSA-5632681	4.305113e-01	0.366	0	0
Separation of Sister Chromatids	R-HSA-2467813	2.183716e-01	0.661	0	0
Regulation of TP53 Activity through Methylation	R-HSA-6804760	4.810923e-01	0.318	0	0
Regulation of signaling by CBL	R-HSA-912631	2.397170e-01	0.620	0	0
Transcriptional regulation of brown and beige adipocyte differentiation	R-HSA-9843743	4.212844e-01	0.375	0	0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	R-HSA-9844594	4.212844e-01	0.375	0	0
Positive epigenetic regulation of rRNA expression	R-HSA-5250913	4.812985e-01	0.318	0	0
MET activates RAS signaling	R-HSA-8851805	3.104113e-01	0.508	0	0
DNA Double-Strand Break Repair	R-HSA-5693532	4.276537e-01	0.369	0	0
Insulin receptor signalling cascade	R-HSA-74751	2.472025e-01	0.607	1	0
Calcineurin activates NFAT	R-HSA-2025928	2.071969e-01	0.684	0	0
Formation of the posterior neural plate	R-HSA-9832991	2.587332e-01	0.587	0	0
IRF3 mediated activation of type 1 IFN	R-HSA-1606341	3.889790e-01	0.410	0	0
Post-transcriptional silencing by small RNAs	R-HSA-426496	3.889790e-01	0.410	0	0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	R-HSA-176407	2.031933e-01	0.692	0	0
HDR through Single Strand Annealing (SSA)	R-HSA-5685938	2.955670e-01	0.529	0	0
mRNA decay by 5' to 3' exoribonuclease	R-HSA-430039	4.347381e-01	0.362	0	0
Regulation of actin dynamics for phagocytic cup formation	R-HSA-2029482	2.287579e-01	0.641	1	1
Trafficking of GluR2-containing AMPA receptors	R-HSA-416993	4.810923e-01	0.318	0	0
Gap junction trafficking	R-HSA-190828	1.637484e-01	0.786	0	0
Pre-NOTCH Transcription and Translation	R-HSA-1912408	1.725412e-01	0.763	0	0
DNA Double Strand Break Response	R-HSA-5693606	4.326298e-01	0.364	0	0
TP53 Regulates Transcription of Cell Cycle Genes	R-HSA-6791312	1.780842e-01	0.749	0	0
Mitotic Prometaphase	R-HSA-68877	3.271655e-01	0.485	0	0
Ephrin signaling	R-HSA-3928664	4.810923e-01	0.318	0	0
Downregulation of ERBB2:ERBB3 signaling	R-HSA-1358803	3.104113e-01	0.508	0	0
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	2.471789e-01	0.607	0	0
Transcriptional activation of cell cycle inhibitor p21	R-HSA-69895	3.444207e-01	0.463	0	0
SARS-CoV-1-mediated effects on programmed cell death	R-HSA-9692913	3.444207e-01	0.463	0	0
Transcriptional activation of p53 responsive genes	R-HSA-69560	3.444207e-01	0.463	0	0
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	R-HSA-3772470	2.846185e-01	0.546	0	0
WNT5A-dependent internalization of FZD4	R-HSA-5099900	4.107346e-01	0.386	0	0
TNFR1-induced NF-kappa-B signaling pathway	R-HSA-5357956	4.098384e-01	0.387	0	0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	R-HSA-164938	4.582032e-01	0.339	0	0
Switching of origins to a post-replicative state	R-HSA-69052	3.453726e-01	0.462	0	0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	R-HSA-6804116	1.681534e-01	0.774	0	0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	R-HSA-9615017	4.521712e-01	0.345	0	0
MET promotes cell motility	R-HSA-8875878	2.131840e-01	0.671	0	0
IRS-related events triggered by IGF1R	R-HSA-2428928	3.585264e-01	0.445	0	0
HDR through Homologous Recombination (HRR)	R-HSA-5685942	4.326298e-01	0.364	0	0
Regulation of gene expression by Hypoxia-inducible Factor	R-HSA-1234158	2.846185e-01	0.546	0	0
Sema4D induced cell migration and growth-cone collapse	R-HSA-416572	2.583738e-01	0.588	0	0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	R-HSA-9673767	3.862388e-01	0.413	0	0
Signaling by PDGFRA extracellular domain mutants	R-HSA-9673770	3.862388e-01	0.413	0	0
Activated NOTCH1 Transmits Signal to the Nucleus	R-HSA-2122948	3.911291e-01	0.408	0	0
M-decay: degradation of maternal mRNAs by maternally stored factors	R-HSA-9820841	4.367882e-01	0.360	0	0
MTOR signalling	R-HSA-165159	2.778117e-01	0.556	0	0
HCMV Infection	R-HSA-9609646	4.391222e-01	0.357	0	0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	R-HSA-6804114	1.854544e-01	0.732	0	0
ZBP1(DAI) mediated induction of type I IFNs	R-HSA-1606322	4.810923e-01	0.318	0	0
G2/M Checkpoints	R-HSA-69481	3.016976e-01	0.520	0	0
PIP3 activates AKT signaling	R-HSA-1257604	1.745801e-01	0.758	1	0
IGF1R signaling cascade	R-HSA-2428924	3.956246e-01	0.403	0	0
trans-Golgi Network Vesicle Budding	R-HSA-199992	3.341558e-01	0.476	0	0
Regulation of TP53 Expression and Degradation	R-HSA-6806003	2.257277e-01	0.646	0	0
Pre-NOTCH Expression and Processing	R-HSA-1912422	3.854900e-01	0.414	0	0
Transport of connexins along the secretory pathway	R-HSA-190827	1.903056e-01	0.721	0	0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	R-HSA-5368598	2.966161e-01	0.528	0	0
AKT phosphorylates targets in the nucleus	R-HSA-198693	2.071969e-01	0.684	0	0
Unwinding of DNA	R-HSA-176974	2.071969e-01	0.684	0	0
Inhibition of TSC complex formation by PKB	R-HSA-165181	3.444207e-01	0.463	0	0
Differentiation of T cells	R-HSA-9945266	1.681534e-01	0.774	0	0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)	R-HSA-9942503	1.681534e-01	0.774	0	0
Inactivation of APC/C via direct inhibition of the APC/C complex	R-HSA-141430	1.854544e-01	0.732	0	0
Reelin signalling pathway	R-HSA-8866376	3.889790e-01	0.410	0	0
Regulation of FZD by ubiquitination	R-HSA-4641263	2.031933e-01	0.692	0	0
NFE2L2 regulates pentose phosphate pathway genes	R-HSA-9818028	2.846185e-01	0.546	0	0
Mitotic Telophase/Cytokinesis	R-HSA-68884	2.846185e-01	0.546	0	0
Signaling by AXIN mutants	R-HSA-4839735	2.846185e-01	0.546	0	0
Signaling by AMER1 mutants	R-HSA-4839748	2.846185e-01	0.546	0	0
Recognition of DNA damage by PCNA-containing replication complex	R-HSA-110314	3.533083e-01	0.452	0	0
Deadenylation of mRNA	R-HSA-429947	3.533083e-01	0.452	0	0
G2/M DNA damage checkpoint	R-HSA-69473	2.245247e-01	0.649	0	0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function	R-HSA-9701190	3.269319e-01	0.486	0	0
Interaction between L1 and Ankyrins	R-HSA-445095	4.098384e-01	0.387	0	0
Regulation of PD-L1(CD274) expression	R-HSA-9909648	1.963838e-01	0.707	0	0
RNA Polymerase III Transcription Termination	R-HSA-73980	4.810923e-01	0.318	0	0
Developmental Cell Lineages of the Integumentary System	R-HSA-9734779	3.393851e-01	0.469	0	0
Cellular response to hypoxia	R-HSA-1234174	4.079858e-01	0.389	0	0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	R-HSA-166058	4.598212e-01	0.337	1	0
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	4.598212e-01	0.337	1	0
FCGR3A-mediated phagocytosis	R-HSA-9664422	3.158816e-01	0.500	1	1
Parasite infection	R-HSA-9664407	3.158816e-01	0.500	1	0
Leishmania phagocytosis	R-HSA-9664417	3.158816e-01	0.500	1	0
RAF/MAP kinase cascade	R-HSA-5673001	2.042825e-01	0.690	1	1
Intracellular signaling by second messengers	R-HSA-9006925	2.063120e-01	0.685	1	0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	4.079858e-01	0.389	0	0
Vesicle-mediated transport	R-HSA-5653656	4.297035e-01	0.367	0	0
Aggrephagy	R-HSA-9646399	4.212844e-01	0.375	0	0
CaMK IV-mediated phosphorylation of CREB	R-HSA-111932	2.328786e-01	0.633	0	0
Formation of definitive endoderm	R-HSA-9823730	2.583738e-01	0.588	0	0
Co-inhibition by PD-1	R-HSA-389948	3.751914e-01	0.426	0	0
CD209 (DC-SIGN) signaling	R-HSA-5621575	1.632431e-01	0.787	0	0
EGFR downregulation	R-HSA-182971	2.646178e-01	0.577	0	0
Signaling by NOTCH4	R-HSA-9013694	3.566321e-01	0.448	0	0
Interleukin-4 and Interleukin-13 signaling	R-HSA-6785807	4.160200e-01	0.381	0	0
PTK6 Activates STAT3	R-HSA-8849474	3.889790e-01	0.410	0	0
IRS-mediated signalling	R-HSA-112399	3.095029e-01	0.509	0	0
Regulation of TNFR1 signaling	R-HSA-5357905	3.319772e-01	0.479	0	0
MAPK1/MAPK3 signaling	R-HSA-5684996	2.365570e-01	0.626	1	0
Mitotic Anaphase	R-HSA-68882	3.977073e-01	0.400	0	0
Receptor Mediated Mitophagy	R-HSA-8934903	2.328786e-01	0.633	0	0
Ovarian tumor domain proteases	R-HSA-5689896	2.008721e-01	0.697	0	0
Signaling by CSF1 (M-CSF) in myeloid cells	R-HSA-9680350	3.269319e-01	0.486	0	0
Acetylcholine regulates insulin secretion	R-HSA-399997	4.347381e-01	0.362	0	0
Fcgamma receptor (FCGR) dependent phagocytosis	R-HSA-2029480	3.848097e-01	0.415	1	0
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	1.987691e-01	0.702	1	0
Mitotic Metaphase and Anaphase	R-HSA-2555396	4.045042e-01	0.393	0	0
FLT3 signaling in disease	R-HSA-9682385	1.888120e-01	0.724	0	0
Prolonged ERK activation events	R-HSA-169893	4.107346e-01	0.386	1	0
ESR-mediated signaling	R-HSA-8939211	4.455279e-01	0.351	1	1
Regulation of T cell activation by CD28 family	R-HSA-388841	4.778647e-01	0.321	0	0
Negative regulation of MET activity	R-HSA-6807004	2.583738e-01	0.588	0	0
Evasion by RSV of host interferon responses	R-HSA-9833109	2.646178e-01	0.577	0	0
DCC mediated attractive signaling	R-HSA-418885	3.862388e-01	0.413	0	0
MyD88 dependent cascade initiated on endosome	R-HSA-975155	4.790174e-01	0.320	1	0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	R-HSA-442729	1.818502e-01	0.740	0	0
Regulation of CDH19 Expression and Function	R-HSA-9764302	4.305113e-01	0.366	0	0
Homologous DNA Pairing and Strand Exchange	R-HSA-5693579	3.899957e-01	0.409	0	0
MyD88 cascade initiated on plasma membrane	R-HSA-975871	3.612271e-01	0.442	1	0
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	3.612271e-01	0.442	1	0
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	3.612271e-01	0.442	1	0
Constitutive Signaling by EGFRvIII	R-HSA-5637810	4.582032e-01	0.339	0	0
Signaling by EGFRvIII in Cancer	R-HSA-5637812	4.582032e-01	0.339	0	0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	4.692931e-01	0.329	1	0
mTORC1-mediated signalling	R-HSA-166208	3.152153e-01	0.501	0	0
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	4.133879e-01	0.384	1	0
Rab regulation of trafficking	R-HSA-9007101	4.412876e-01	0.355	0	0
Semaphorin interactions	R-HSA-373755	2.368382e-01	0.626	0	0
Protein-protein interactions at synapses	R-HSA-6794362	4.805525e-01	0.318	0	0
Toll-like Receptor Cascades	R-HSA-168898	4.087747e-01	0.389	1	0
TBC/RABGAPs	R-HSA-8854214	2.912079e-01	0.536	0	0
Influenza Viral RNA Transcription and Replication	R-HSA-168273	4.438267e-01	0.353	0	0
MAPK6/MAPK4 signaling	R-HSA-5687128	3.334101e-01	0.477	0	0
Cellular responses to stimuli	R-HSA-8953897	3.407486e-01	0.468	1	0
Signalling to ERKs	R-HSA-187687	3.426968e-01	0.465	1	0
Interleukin-17 signaling	R-HSA-448424	1.885890e-01	0.724	1	0
Oligomerization of connexins into connexons	R-HSA-190704	1.903056e-01	0.721	0	0
TLR3-mediated TICAM1-dependent programmed cell death	R-HSA-9013957	3.444207e-01	0.463	0	0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	R-HSA-428359	2.328786e-01	0.633	0	0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	R-HSA-141405	1.854544e-01	0.732	0	0
Synthesis of PI	R-HSA-1483226	2.587332e-01	0.587	0	0
Negative feedback regulation of MAPK pathway	R-HSA-5674499	4.305113e-01	0.366	1	1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	R-HSA-2173796	2.008721e-01	0.697	1	1
Signaling by FGFR4 in disease	R-HSA-5655291	3.613067e-01	0.442	0	0
CLEC7A (Dectin-1) induces NFAT activation	R-HSA-5607763	3.613067e-01	0.442	0	0
Integration of viral DNA into host genomic DNA	R-HSA-175567	4.692229e-01	0.329	0	0
Ca2+ pathway	R-HSA-4086398	3.453726e-01	0.462	0	0
TRIF (TICAM1)-mediated TLR4 signaling	R-HSA-937061	2.453587e-01	0.610	1	0
Programmed Cell Death	R-HSA-5357801	3.241904e-01	0.489	1	0
MyD88-independent TLR4 cascade	R-HSA-166166	2.453587e-01	0.610	1	0
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	2.071211e-01	0.684	1	0
HCMV Late Events	R-HSA-9610379	4.599693e-01	0.337	0	0
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	2.343324e-01	0.630	1	0
Sema4D in semaphorin signaling	R-HSA-400685	3.722734e-01	0.429	0	0
Cyclin E associated events during G1/S transition	R-HSA-69202	3.118912e-01	0.506	0	0
Defective Intrinsic Pathway for Apoptosis	R-HSA-9734009	2.049705e-01	0.688	0	0
Signaling by PDGF	R-HSA-186797	2.266209e-01	0.645	0	0
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-5693616	3.426968e-01	0.465	0	0
Neurodegenerative Diseases	R-HSA-8863678	3.533083e-01	0.452	0	0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	R-HSA-8862803	3.533083e-01	0.452	0	0
Synthesis of PIPs at the plasma membrane	R-HSA-1660499	3.708826e-01	0.431	0	0
Signaling by PTK6	R-HSA-8848021	2.368382e-01	0.626	0	0
Signaling by Non-Receptor Tyrosine Kinases	R-HSA-9006927	2.368382e-01	0.626	0	0
Maternal to zygotic transition (MZT)	R-HSA-9816359	3.717348e-01	0.430	0	0
Apoptosis	R-HSA-109581	2.064289e-01	0.685	1	0
RSV-host interactions	R-HSA-9833110	1.997966e-01	0.699	0	0
Signaling by VEGF	R-HSA-194138	1.936110e-01	0.713	0	0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	R-HSA-2173793	1.689528e-01	0.772	1	0
Intrinsic Pathway for Apoptosis	R-HSA-109606	1.689528e-01	0.772	1	0
The NLRP1 inflammasome	R-HSA-844455	2.966161e-01	0.528	0	0
Activation of the TFAP2 (AP-2) family of transcription factors	R-HSA-8866907	2.071969e-01	0.684	0	0
Dopamine receptors	R-HSA-390651	3.444207e-01	0.463	0	0
GLI proteins bind promoters of Hh responsive genes to promote transcription	R-HSA-5635851	4.305113e-01	0.366	0	0
PI5P Regulates TP53 Acetylation	R-HSA-6811555	3.360047e-01	0.474	0	0
CREB phosphorylation	R-HSA-199920	4.692229e-01	0.329	0	0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	R-HSA-9725554	4.056798e-01	0.392	0	0
EPH-Ephrin signaling	R-HSA-2682334	4.276750e-01	0.369	0	0
SARS-CoV-2-host interactions	R-HSA-9705683	2.252950e-01	0.647	0	0
Netrin-1 signaling	R-HSA-373752	3.047140e-01	0.516	0	0
Sensory processing of sound	R-HSA-9659379	1.649884e-01	0.783	0	0
Signaling by SCF-KIT	R-HSA-1433557	2.912079e-01	0.536	0	0
Cyclin A/B1/B2 associated events during G2/M transition	R-HSA-69273	2.955670e-01	0.529	0	0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	R-HSA-5358606	4.582032e-01	0.339	0	0
Cyclin A:Cdk2-associated events at S phase entry	R-HSA-69656	3.341558e-01	0.476	0	0
Uptake and function of anthrax toxins	R-HSA-5210891	2.031933e-01	0.692	0	0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	R-HSA-2660825	4.305113e-01	0.366	0	0
Release of Hh-Np from the secreting cell	R-HSA-5362798	4.305113e-01	0.366	0	0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	R-HSA-2660826	4.305113e-01	0.366	0	0
Formation of the anterior neural plate	R-HSA-9823739	3.862388e-01	0.413	0	0
EML4 and NUDC in mitotic spindle formation	R-HSA-9648025	2.375089e-01	0.624	0	0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	R-HSA-5358565	4.582032e-01	0.339	0	0
Assembly of collagen fibrils and other multimeric structures	R-HSA-2022090	3.339079e-01	0.476	0	0
Cytoprotection by HMOX1	R-HSA-9707564	1.964746e-01	0.707	0	0
Signaling by TGF-beta Receptor Complex	R-HSA-170834	3.514598e-01	0.454	1	0
Josephin domain DUBs	R-HSA-5689877	2.328786e-01	0.633	0	0
Constitutive Signaling by AKT1 E17K in Cancer	R-HSA-5674400	3.342744e-01	0.476	0	0
Receptor-type tyrosine-protein phosphatases	R-HSA-388844	4.107346e-01	0.386	0	0
PI3K Cascade	R-HSA-109704	3.869834e-01	0.412	0	0
Neurofascin interactions	R-HSA-447043	4.692229e-01	0.329	0	0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	R-HSA-9735871	3.862388e-01	0.413	0	0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	R-HSA-8864260	3.047140e-01	0.516	0	0
Antiviral mechanism by IFN-stimulated genes	R-HSA-1169410	1.618933e-01	0.791	1	0
Sensory processing of sound by outer hair cells of the cochlea	R-HSA-9662361	1.689528e-01	0.772	0	0
Kidney development	R-HSA-9830369	4.326298e-01	0.364	0	0
Mismatch Repair	R-HSA-5358508	4.810923e-01	0.318	0	0
Interleukin-7 signaling	R-HSA-1266695	1.767988e-01	0.753	0	0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	R-HSA-8866910	4.347381e-01	0.362	0	0
Signaling by Leptin	R-HSA-2586552	2.328786e-01	0.633	0	0
Respiratory Syncytial Virus Infection Pathway	R-HSA-9820952	4.009930e-01	0.397	0	0
tRNA processing	R-HSA-72306	3.551659e-01	0.450	0	0
Interleukin-37 signaling	R-HSA-9008059	2.493762e-01	0.603	0	0
Growth hormone receptor signaling	R-HSA-982772	3.342744e-01	0.476	1	1
Trafficking of AMPA receptors	R-HSA-399719	4.825736e-01	0.316	0	0
Cargo concentration in the ER	R-HSA-5694530	4.825736e-01	0.316	0	0
Ub-specific processing proteases	R-HSA-5689880	4.830690e-01	0.316	0	0
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	4.874266e-01	0.312	1	0
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	4.874266e-01	0.312	1	0
Mitotic G2-G2/M phases	R-HSA-453274	4.895475e-01	0.310	0	0
Developmental Lineages of the Mammary Gland	R-HSA-9924644	4.932780e-01	0.307	0	0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	R-HSA-9029569	4.951894e-01	0.305	0	0
EPHB-mediated forward signaling	R-HSA-3928662	4.974168e-01	0.303	0	0
RMTs methylate histone arginines	R-HSA-3214858	4.974168e-01	0.303	0	0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells	R-HSA-9937080	5.000984e-01	0.301	0	0
Impaired BRCA2 binding to PALB2	R-HSA-9709603	5.033752e-01	0.298	0	0
STING mediated induction of host immune responses	R-HSA-1834941	5.033752e-01	0.298	0	0
Rap1 signalling	R-HSA-392517	5.033752e-01	0.298	0	0
Translocation of SLC2A4 (GLUT4) to the plasma membrane	R-HSA-1445148	5.051640e-01	0.297	0	0
MET activates PI3K/AKT signaling	R-HSA-8851907	5.053051e-01	0.296	0	0
RUNX3 Regulates Immune Response and Cell Migration	R-HSA-8949275	5.053051e-01	0.296	0	0
Role of ABL in ROBO-SLIT signaling	R-HSA-428890	5.053051e-01	0.296	0	0
IFNG signaling activates MAPKs	R-HSA-9732724	5.053051e-01	0.296	1	1
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis	R-HSA-9632974	5.053051e-01	0.296	0	0
Disinhibition of SNARE formation	R-HSA-114516	5.053051e-01	0.296	0	0
SHOC2 M1731 mutant abolishes MRAS complex function	R-HSA-9726840	5.053051e-01	0.296	0	0
RUNX1 regulates estrogen receptor mediated transcription	R-HSA-8931987	5.053051e-01	0.296	0	0
PTK6 Expression	R-HSA-8849473	5.053051e-01	0.296	0	0
Nef Mediated CD4 Down-regulation	R-HSA-167590	5.053051e-01	0.296	0	0
Microbial modulation of RIPK1-mediated regulated necrosis	R-HSA-9686347	5.053051e-01	0.296	0	0
Activated NTRK3 signals through PI3K	R-HSA-9603381	5.053051e-01	0.296	0	0
VLDL clearance	R-HSA-8964046	5.053051e-01	0.296	0	0
TRIF-mediated programmed cell death	R-HSA-2562578	5.053051e-01	0.296	0	0
Regulation of PTEN localization	R-HSA-8948747	5.053051e-01	0.296	0	0
Displacement of DNA glycosylase by APEX1	R-HSA-110357	5.053051e-01	0.296	0	0
Deadenylation-dependent mRNA decay	R-HSA-429914	5.082689e-01	0.294	0	0
Beta-catenin independent WNT signaling	R-HSA-3858494	5.122235e-01	0.291	0	0
Resolution of D-loop Structures through Holliday Junction Intermediates	R-HSA-5693568	5.173157e-01	0.286	0	0
Glutamate binding, activation of AMPA receptors and synaptic plasticity	R-HSA-399721	5.173157e-01	0.286	0	0
Activation of ATR in response to replication stress	R-HSA-176187	5.173157e-01	0.286	0	0
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	5.174561e-01	0.286	1	0
Organelle biogenesis and maintenance	R-HSA-1852241	5.216330e-01	0.283	0	0
Selective autophagy	R-HSA-9663891	5.242630e-01	0.280	0	0
Defective homologous recombination repair (HRR) due to PALB2 loss of function	R-HSA-9701193	5.250286e-01	0.280	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	R-HSA-9704646	5.250286e-01	0.280	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	R-HSA-9704331	5.250286e-01	0.280	0	0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	R-HSA-9701192	5.250286e-01	0.280	0	0
Signal transduction by L1	R-HSA-445144	5.250286e-01	0.280	1	1
Nephrin family interactions	R-HSA-373753	5.250286e-01	0.280	0	0
mRNA Splicing - Minor Pathway	R-HSA-72165	5.266705e-01	0.278	0	0
Autodegradation of Cdh1 by Cdh1:APC/C	R-HSA-174084	5.266705e-01	0.278	0	0
Diseases of DNA repair	R-HSA-9675135	5.266705e-01	0.278	0	0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	R-HSA-5693567	5.269268e-01	0.278	0	0
Formation of paraxial mesoderm	R-HSA-9793380	5.340029e-01	0.272	0	0
Resolution of D-Loop Structures	R-HSA-5693537	5.342081e-01	0.272	0	0
Association of TriC/CCT with target proteins during biosynthesis	R-HSA-390471	5.342081e-01	0.272	0	0
Effects of PIP2 hydrolysis	R-HSA-114508	5.342081e-01	0.272	0	0
Activation of RAS in B cells	R-HSA-1169092	5.389366e-01	0.268	0	0
Activated NTRK2 signals through PI3K	R-HSA-9028335	5.389366e-01	0.268	0	0
Signaling by MRAS-complex mutants	R-HSA-9660537	5.389366e-01	0.268	0	0
Regulation of NPAS4 mRNA translation	R-HSA-9768778	5.389366e-01	0.268	0	0
Myoclonic epilepsy of Lafora	R-HSA-3785653	5.389366e-01	0.268	0	0
Gain-of-function MRAS complexes activate RAF signaling	R-HSA-9726842	5.389366e-01	0.268	0	0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	R-HSA-8939242	5.389366e-01	0.268	0	0
Nef mediated downregulation of MHC class I complex cell surface expression	R-HSA-164940	5.389366e-01	0.268	0	0
Adrenoceptors	R-HSA-390696	5.389366e-01	0.268	0	0
Axonal growth inhibition (RHOA activation)	R-HSA-193634	5.389366e-01	0.268	0	0
Co-stimulation by ICOS	R-HSA-9927354	5.389366e-01	0.268	0	0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	R-HSA-8849469	5.389366e-01	0.268	0	0
Apoptotic cleavage of cell adhesion proteins	R-HSA-351906	5.389366e-01	0.268	0	0
APC/C:Cdc20 mediated degradation of Securin	R-HSA-174154	5.409836e-01	0.267	0	0
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	5.409836e-01	0.267	0	0
TNFR1-induced proapoptotic signaling	R-HSA-5357786	5.460351e-01	0.263	0	0
Acetylcholine Neurotransmitter Release Cycle	R-HSA-264642	5.460351e-01	0.263	0	0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	R-HSA-1236382	5.460351e-01	0.263	0	0
Signaling by Ligand-Responsive EGFR Variants in Cancer	R-HSA-5637815	5.460351e-01	0.263	0	0
Signalling to RAS	R-HSA-167044	5.460351e-01	0.263	0	0
ERK/MAPK targets	R-HSA-198753	5.460351e-01	0.263	1	1
Early Phase of HIV Life Cycle	R-HSA-162594	5.460351e-01	0.263	0	0
Signaling by NOTCH2	R-HSA-1980145	5.507604e-01	0.259	0	0
Macroautophagy	R-HSA-1632852	5.546301e-01	0.256	0	0
Nonhomologous End-Joining (NHEJ)	R-HSA-5693571	5.550724e-01	0.256	0	0
Unblocking of NMDA receptors, glutamate binding and activation	R-HSA-438066	5.663826e-01	0.247	0	0
Ras activation upon Ca2+ influx through NMDA receptor	R-HSA-442982	5.663826e-01	0.247	0	0
Gap-filling DNA repair synthesis and ligation in GG-NER	R-HSA-5696397	5.663826e-01	0.247	0	0
Negative regulation of NMDA receptor-mediated neuronal transmission	R-HSA-9617324	5.663826e-01	0.247	0	0
Signaling by NTRK3 (TRKC)	R-HSA-9034015	5.663826e-01	0.247	0	0
Autophagy	R-HSA-9612973	5.666010e-01	0.247	0	0
DNA Damage Bypass	R-HSA-73893	5.689267e-01	0.245	0	0
ARMS-mediated activation	R-HSA-170984	5.702834e-01	0.244	0	0
ALK mutants bind TKIs	R-HSA-9700645	5.702834e-01	0.244	0	0
AMPK inhibits chREBP transcriptional activation activity	R-HSA-163680	5.702834e-01	0.244	0	0
Activation of the AP-1 family of transcription factors	R-HSA-450341	5.702834e-01	0.244	1	1
IRAK2 mediated activation of TAK1 complex	R-HSA-937042	5.702834e-01	0.244	0	0
Regulation of commissural axon pathfinding by SLIT and ROBO	R-HSA-428542	5.702834e-01	0.244	0	0
p75NTR regulates axonogenesis	R-HSA-193697	5.702834e-01	0.244	0	0
WNT mediated activation of DVL	R-HSA-201688	5.702834e-01	0.244	0	0
GP1b-IX-V activation signalling	R-HSA-430116	5.702834e-01	0.244	0	0
Regulated proteolysis of p75NTR	R-HSA-193692	5.702834e-01	0.244	0	0
Lipophagy	R-HSA-9613354	5.702834e-01	0.244	0	0
Signaling by Insulin receptor	R-HSA-74752	5.768107e-01	0.239	1	0
Homology Directed Repair	R-HSA-5693538	5.822481e-01	0.235	0	0
PI3K/AKT Signaling in Cancer	R-HSA-2219528	5.822481e-01	0.235	0	0
Calmodulin induced events	R-HSA-111933	5.827946e-01	0.234	0	0
CaM pathway	R-HSA-111997	5.827946e-01	0.234	0	0
RNA Polymerase III Abortive And Retractive Initiation	R-HSA-749476	5.827946e-01	0.234	0	0
RNA Polymerase III Transcription	R-HSA-74158	5.827946e-01	0.234	0	0
DNA Repair	R-HSA-73894	5.841040e-01	0.234	0	0
Nuclear Envelope (NE) Reassembly	R-HSA-2995410	5.850977e-01	0.233	0	0
Developmental Lineage of Mammary Stem Cells	R-HSA-9938206	5.860636e-01	0.232	0	0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	R-HSA-9670439	5.860636e-01	0.232	0	0
LDL clearance	R-HSA-8964038	5.860636e-01	0.232	0	0
RAF-independent MAPK1/3 activation	R-HSA-112409	5.860636e-01	0.232	1	1
Signaling by KIT in disease	R-HSA-9669938	5.860636e-01	0.232	0	0
Downregulation of TGF-beta receptor signaling	R-HSA-2173788	5.860636e-01	0.232	0	0
Assembly of the pre-replicative complex	R-HSA-68867	5.869857e-01	0.231	0	0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	R-HSA-1234176	5.958972e-01	0.225	0	0
Collagen chain trimerization	R-HSA-8948216	5.982565e-01	0.223	0	0
Establishment of Sister Chromatid Cohesion	R-HSA-2468052	5.995009e-01	0.222	0	0
Erythropoietin activates Phospholipase C gamma (PLCG)	R-HSA-9027277	5.995009e-01	0.222	0	0
DNA replication initiation	R-HSA-68952	5.995009e-01	0.222	0	0
Folding of actin by CCT/TriC	R-HSA-390450	5.995009e-01	0.222	0	0
Apoptosis induced DNA fragmentation	R-HSA-140342	5.995009e-01	0.222	0	0
TICAM1,TRAF6-dependent induction of TAK1 complex	R-HSA-9014325	5.995009e-01	0.222	0	0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	R-HSA-5140745	5.995009e-01	0.222	0	0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	R-HSA-2151209	5.995009e-01	0.222	0	0
Defective RIPK1-mediated regulated necrosis	R-HSA-9693928	5.995009e-01	0.222	0	0
Formation of intermediate mesoderm	R-HSA-9761174	5.995009e-01	0.222	0	0
EGFR Transactivation by Gastrin	R-HSA-2179392	5.995009e-01	0.222	0	0
2-LTR circle formation	R-HSA-164843	5.995009e-01	0.222	0	0
Arachidonate production from DAG	R-HSA-426048	5.995009e-01	0.222	0	0
Regulation of CDH11 function	R-HSA-9762292	5.995009e-01	0.222	0	0
Signaling by Nuclear Receptors	R-HSA-9006931	6.000154e-01	0.222	1	0
RNA Pol II CTD phosphorylation and interaction with CE	R-HSA-77075	6.050747e-01	0.218	0	0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	R-HSA-167160	6.050747e-01	0.218	0	0
The role of Nef in HIV-1 replication and disease pathogenesis	R-HSA-164952	6.050747e-01	0.218	0	0
Carnitine shuttle	R-HSA-200425	6.050747e-01	0.218	0	0
mRNA 3'-end processing	R-HSA-72187	6.089986e-01	0.215	0	0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	R-HSA-174184	6.089986e-01	0.215	0	0
Orc1 removal from chromatin	R-HSA-68949	6.089986e-01	0.215	0	0
Neurexins and neuroligins	R-HSA-6794361	6.089986e-01	0.215	0	0
SARS-CoV-1 activates/modulates innate immune responses	R-HSA-9692916	6.089986e-01	0.215	0	0
DNA Replication Pre-Initiation	R-HSA-69002	6.168862e-01	0.210	0	0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	R-HSA-179419	6.218358e-01	0.206	0	0
B-WICH complex positively regulates rRNA expression	R-HSA-5250924	6.218358e-01	0.206	0	0
Signaling by ERBB2 TMD/JMD mutants	R-HSA-9665686	6.234160e-01	0.205	0	0
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	6.234160e-01	0.205	0	0
Signaling by FLT3 ITD and TKD mutants	R-HSA-9703648	6.234160e-01	0.205	0	0
Norepinephrine Neurotransmitter Release Cycle	R-HSA-181430	6.234160e-01	0.205	0	0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	R-HSA-933543	6.267334e-01	0.203	0	0
Regulation of CDH11 mRNA translation by microRNAs	R-HSA-9759811	6.267334e-01	0.203	0	0
CD163 mediating an anti-inflammatory response	R-HSA-9662834	6.267334e-01	0.203	0	0
Interleukin-2 signaling	R-HSA-9020558	6.267334e-01	0.203	0	0
Regulation of localization of FOXO transcription factors	R-HSA-9614399	6.267334e-01	0.203	0	0
Activated NTRK3 signals through RAS	R-HSA-9034864	6.267334e-01	0.203	0	0
Transport of RCbl within the body	R-HSA-9758890	6.267334e-01	0.203	0	0
Alpha-protein kinase 1 signaling pathway	R-HSA-9645460	6.267334e-01	0.203	0	0
Inorganic anion exchange by SLC26 transporters	R-HSA-427601	6.267334e-01	0.203	0	0
PECAM1 interactions	R-HSA-210990	6.267334e-01	0.203	0	0
RUNX1 regulates transcription of genes involved in differentiation of HSCs	R-HSA-8939236	6.276513e-01	0.202	0	0
Formation of HIV-1 elongation complex containing HIV-1 Tat	R-HSA-167200	6.280339e-01	0.202	0	0
Plasma lipoprotein clearance	R-HSA-8964043	6.280339e-01	0.202	0	0
CDK-mediated phosphorylation and removal of Cdc6	R-HSA-69017	6.344038e-01	0.198	0	0
Influenza Infection	R-HSA-168255	6.359253e-01	0.197	0	0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	R-HSA-5693554	6.410906e-01	0.193	0	0
Long-term potentiation	R-HSA-9620244	6.410906e-01	0.193	0	0
Polymerase switching on the C-strand of the telomere	R-HSA-174411	6.410906e-01	0.193	0	0
Laminin interactions	R-HSA-3000157	6.410906e-01	0.193	0	0
COPII-mediated vesicle transport	R-HSA-204005	6.411811e-01	0.193	0	0
Cytosolic sensors of pathogen-associated DNA	R-HSA-1834949	6.411811e-01	0.193	0	0
Regulation of RUNX3 expression and activity	R-HSA-8941858	6.423398e-01	0.192	0	0
Attenuation phase	R-HSA-3371568	6.423398e-01	0.192	0	0
Inhibition of DNA recombination at telomere	R-HSA-9670095	6.423398e-01	0.192	0	0
Formation of HIV elongation complex in the absence of HIV Tat	R-HSA-167152	6.423398e-01	0.192	0	0
HIV Transcription Elongation	R-HSA-167169	6.423398e-01	0.192	0	0
Tat-mediated elongation of the HIV-1 transcript	R-HSA-167246	6.423398e-01	0.192	0	0
Formation of Incision Complex in GG-NER	R-HSA-5696395	6.423398e-01	0.192	0	0
Nuclear signaling by ERBB4	R-HSA-1251985	6.423398e-01	0.192	0	0
APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176409	6.466985e-01	0.189	0	0
RAB GEFs exchange GTP for GDP on RABs	R-HSA-8876198	6.479513e-01	0.188	0	0
APC/C-mediated degradation of cell cycle proteins	R-HSA-174143	6.520975e-01	0.186	0	0
Regulation of mitotic cell cycle	R-HSA-453276	6.520975e-01	0.186	0	0
Integration of provirus	R-HSA-162592	6.521157e-01	0.186	0	0
Activated NTRK2 signals through RAS	R-HSA-9026519	6.521157e-01	0.186	0	0
NF-kB is activated and signals survival	R-HSA-209560	6.521157e-01	0.186	0	0
APOBEC3G mediated resistance to HIV-1 infection	R-HSA-180689	6.521157e-01	0.186	0	0
POLB-Dependent Long Patch Base Excision Repair	R-HSA-110362	6.521157e-01	0.186	0	0
TICAM1-dependent activation of IRF3/IRF7	R-HSA-9013973	6.521157e-01	0.186	0	0
Anchoring fibril formation	R-HSA-2214320	6.521157e-01	0.186	0	0
Resolution of Abasic Sites (AP sites)	R-HSA-73933	6.562531e-01	0.183	0	0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	R-HSA-110373	6.581044e-01	0.182	0	0
TRP channels	R-HSA-3295583	6.581044e-01	0.182	0	0
Signaling by EGFR in Cancer	R-HSA-1643713	6.581044e-01	0.182	0	0
Metalloprotease DUBs	R-HSA-5689901	6.581044e-01	0.182	0	0
Glutamate Neurotransmitter Release Cycle	R-HSA-210500	6.581044e-01	0.182	0	0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176814	6.587164e-01	0.181	0	0
Gap-filling DNA repair synthesis and ligation in TC-NER	R-HSA-6782210	6.587164e-01	0.181	0	0
Regulation of mRNA stability by proteins that bind AU-rich elements	R-HSA-450531	6.628003e-01	0.179	0	0
Post NMDA receptor activation events	R-HSA-438064	6.675649e-01	0.176	1	0
Telomere C-strand (Lagging Strand) Synthesis	R-HSA-174417	6.697727e-01	0.174	0	0
Processive synthesis on the C-strand of the telomere	R-HSA-174414	6.744656e-01	0.171	0	0
Mitochondrial unfolded protein response (UPRmt)	R-HSA-9841251	6.744656e-01	0.171	0	0
Signaling by FGFR3 in disease	R-HSA-5655332	6.744656e-01	0.171	0	0
Signaling by NTRK2 (TRKB)	R-HSA-9006115	6.744656e-01	0.171	0	0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	R-HSA-193807	6.744656e-01	0.171	0	0
IRAK1 recruits IKK complex	R-HSA-937039	6.757734e-01	0.170	0	0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	R-HSA-975144	6.757734e-01	0.170	0	0
GRB2 events in EGFR signaling	R-HSA-179812	6.757734e-01	0.170	0	0
SHC-related events triggered by IGF1R	R-HSA-2428933	6.757734e-01	0.170	0	0
Activated NTRK2 signals through FRS2 and FRS3	R-HSA-9028731	6.757734e-01	0.170	0	0
Signaling by NOTCH1 HD Domain Mutants in Cancer	R-HSA-2691230	6.757734e-01	0.170	0	0
Constitutive Signaling by NOTCH1 HD Domain Mutants	R-HSA-2691232	6.757734e-01	0.170	0	0
OAS antiviral response	R-HSA-8983711	6.757734e-01	0.170	0	0
AKT phosphorylates targets in the cytosol	R-HSA-198323	6.757734e-01	0.170	0	0
Diseases of programmed cell death	R-HSA-9645723	6.771081e-01	0.169	0	0
SARS-CoV-2 Infection	R-HSA-9694516	6.788666e-01	0.168	0	0
PI Metabolism	R-HSA-1483255	6.814081e-01	0.167	0	0
RNA Polymerase I Transcription Initiation	R-HSA-73762	6.828984e-01	0.166	0	0
Ca-dependent events	R-HSA-111996	6.828984e-01	0.166	0	0
G2/M Transition	R-HSA-69275	6.833657e-01	0.165	0	0
Negative regulation of the PI3K/AKT network	R-HSA-199418	6.905506e-01	0.161	1	0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	R-HSA-8877330	6.978236e-01	0.156	0	0
HDR through MMEJ (alt-NHEJ)	R-HSA-5685939	6.978236e-01	0.156	0	0
Golgi Cisternae Pericentriolar Stack Reorganization	R-HSA-162658	6.978236e-01	0.156	0	0
Acyl chain remodeling of DAG and TAG	R-HSA-1482883	6.978236e-01	0.156	0	0
Membrane binding and targetting of GAG proteins	R-HSA-174490	6.978236e-01	0.156	0	0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	R-HSA-75035	6.978236e-01	0.156	0	0
CD28 dependent Vav1 pathway	R-HSA-389359	6.978236e-01	0.156	0	0
Frs2-mediated activation	R-HSA-170968	6.978236e-01	0.156	1	1
Replication of the SARS-CoV-1 genome	R-HSA-9682706	6.978236e-01	0.156	0	0
Interferon Signaling	R-HSA-913531	7.035404e-01	0.153	1	0
Late endosomal microautophagy	R-HSA-9615710	7.052717e-01	0.152	0	0
mRNA Capping	R-HSA-72086	7.052717e-01	0.152	0	0
Downstream signaling of activated FGFR3	R-HSA-5654708	7.052717e-01	0.152	0	0
Termination of translesion DNA synthesis	R-HSA-5656169	7.052717e-01	0.152	0	0
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	7.107692e-01	0.148	0	0
RNA Polymerase II Transcription Termination	R-HSA-73856	7.145905e-01	0.146	0	0
PLC beta mediated events	R-HSA-112043	7.145905e-01	0.146	0	0
Collagen degradation	R-HSA-1442490	7.145905e-01	0.146	0	0
ERBB2 Activates PTK6 Signaling	R-HSA-8847993	7.183754e-01	0.144	0	0
CRMPs in Sema3A signaling	R-HSA-399956	7.183754e-01	0.144	0	0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	R-HSA-975163	7.183754e-01	0.144	0	0
Synthesis And Processing Of GAG, GAGPOL Polyproteins	R-HSA-174495	7.183754e-01	0.144	0	0
MAP3K8 (TPL2)-dependent MAPK1/3 activation	R-HSA-5684264	7.183754e-01	0.144	0	0
Regulation of KIT signaling	R-HSA-1433559	7.183754e-01	0.144	0	0
HDL assembly	R-HSA-8963896	7.183754e-01	0.144	0	0
SARS-CoV-1 Genome Replication and Transcription	R-HSA-9679514	7.183754e-01	0.144	0	0
DAP12 signaling	R-HSA-2424491	7.197415e-01	0.143	0	0
Downstream signaling of activated FGFR4	R-HSA-5654716	7.197415e-01	0.143	0	0
DAG and IP3 signaling	R-HSA-1489509	7.199273e-01	0.143	0	0
Signaling by Interleukins	R-HSA-449147	7.201634e-01	0.143	1	0
ER to Golgi Anterograde Transport	R-HSA-199977	7.231024e-01	0.141	0	0
Regulation of APC/C activators between G1/S and early anaphase	R-HSA-176408	7.249185e-01	0.140	0	0
DNA Damage/Telomere Stress Induced Senescence	R-HSA-2559586	7.249185e-01	0.140	0	0
Metabolism of RNA	R-HSA-8953854	7.303914e-01	0.136	0	0
Negative regulators of DDX58/IFIH1 signaling	R-HSA-936440	7.336078e-01	0.135	0	0
Budding and maturation of HIV virion	R-HSA-162588	7.336078e-01	0.135	0	0
Extracellular matrix organization	R-HSA-1474244	7.361131e-01	0.133	0	0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	R-HSA-8948700	7.375306e-01	0.132	0	0
ERBB2 Regulates Cell Motility	R-HSA-6785631	7.375306e-01	0.132	0	0
Telomere C-strand synthesis initiation	R-HSA-174430	7.375306e-01	0.132	0	0
TRAF6-mediated induction of TAK1 complex within TLR4 complex	R-HSA-937072	7.375306e-01	0.132	0	0
Sema3A PAK dependent Axon repulsion	R-HSA-399954	7.375306e-01	0.132	0	0
RIP-mediated NFkB activation via ZBP1	R-HSA-1810476	7.375306e-01	0.132	0	0
SHC1 events in EGFR signaling	R-HSA-180336	7.375306e-01	0.132	0	0
TICAM1, RIP1-mediated IKK complex recruitment	R-HSA-168927	7.375306e-01	0.132	0	0
InlB-mediated entry of Listeria monocytogenes into host cell	R-HSA-8875360	7.375306e-01	0.132	0	0
p38MAPK events	R-HSA-171007	7.375306e-01	0.132	0	0
Activation of BAD and translocation to mitochondria	R-HSA-111447	7.375306e-01	0.132	0	0
Other semaphorin interactions	R-HSA-416700	7.375306e-01	0.132	0	0
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	7.388525e-01	0.131	0	0
Collagen formation	R-HSA-1474290	7.388525e-01	0.131	0	0
TAK1-dependent IKK and NF-kappa-B activation	R-HSA-445989	7.426874e-01	0.129	0	0
Synthesis of PC	R-HSA-1483191	7.426874e-01	0.129	0	0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	R-HSA-6811558	7.466415e-01	0.127	1	1
MHC class II antigen presentation	R-HSA-2132295	7.466415e-01	0.127	0	0
Downregulation of SMAD2/3:SMAD4 transcriptional activity	R-HSA-2173795	7.468856e-01	0.127	1	1
SLC transporter disorders	R-HSA-5619102	7.512248e-01	0.124	0	0
Muscle contraction	R-HSA-397014	7.528506e-01	0.123	0	0
Co-stimulation by CD28	R-HSA-389356	7.535031e-01	0.123	0	0
TP53 Regulates Transcription of Caspase Activators and Caspases	R-HSA-6803207	7.553840e-01	0.122	0	0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	R-HSA-399955	7.553840e-01	0.122	0	0
Class I peroxisomal membrane protein import	R-HSA-9603798	7.553840e-01	0.122	0	0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	R-HSA-434316	7.553840e-01	0.122	0	0
WNT5:FZD7-mediated leishmania damping	R-HSA-9673324	7.553840e-01	0.122	0	0
Killing mechanisms	R-HSA-9664420	7.553840e-01	0.122	0	0
Regulation of NF-kappa B signaling	R-HSA-9758274	7.553840e-01	0.122	0	0
Activation of SMO	R-HSA-5635838	7.553840e-01	0.122	0	0
Senescence-Associated Secretory Phenotype (SASP)	R-HSA-2559582	7.577520e-01	0.120	1	1
Regulation of necroptotic cell death	R-HSA-5675482	7.595908e-01	0.119	0	0
G-protein beta:gamma signalling	R-HSA-397795	7.595908e-01	0.119	0	0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	R-HSA-442742	7.595908e-01	0.119	1	0
Recycling of bile acids and salts	R-HSA-159418	7.595908e-01	0.119	0	0
DNA Replication	R-HSA-69306	7.617502e-01	0.118	0	0
Telomere Maintenance	R-HSA-157579	7.701204e-01	0.113	0	0
NFE2L2 regulating anti-oxidant/detoxification enzymes	R-HSA-9818027	7.717398e-01	0.113	0	0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane	R-HSA-9768727	7.717398e-01	0.113	0	0
G beta:gamma signalling through CDC42	R-HSA-8964616	7.720240e-01	0.112	0	0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	R-HSA-975110	7.720240e-01	0.112	0	0
SHC1 events in ERBB4 signaling	R-HSA-1250347	7.720240e-01	0.112	0	0
STAT5 activation downstream of FLT3 ITD mutants	R-HSA-9702518	7.720240e-01	0.112	0	0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	R-HSA-936964	7.720240e-01	0.112	0	0
Fibronectin matrix formation	R-HSA-1566977	7.720240e-01	0.112	0	0
Regulation of innate immune responses to cytosolic DNA	R-HSA-3134975	7.720240e-01	0.112	0	0
tRNA modification in the mitochondrion	R-HSA-6787450	7.720240e-01	0.112	0	0
Transcriptional regulation of testis differentiation	R-HSA-9690406	7.720240e-01	0.112	0	0
G-protein mediated events	R-HSA-112040	7.723880e-01	0.112	0	0
Signaling by FGFR2 in disease	R-HSA-5655253	7.740340e-01	0.111	0	0
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	7.741025e-01	0.111	0	0
Cytokine Signaling in Immune system	R-HSA-1280215	7.779940e-01	0.109	1	0
Signaling by ROBO receptors	R-HSA-376176	7.823556e-01	0.107	0	0
Dual Incision in GG-NER	R-HSA-5696400	7.833496e-01	0.106	0	0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	R-HSA-9843970	7.833496e-01	0.106	0	0
Autodegradation of the E3 ubiquitin ligase COP1	R-HSA-349425	7.833496e-01	0.106	0	0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	R-HSA-983170	7.833496e-01	0.106	0	0
NOD1/2 Signaling Pathway	R-HSA-168638	7.833496e-01	0.106	0	0
Mitophagy	R-HSA-5205647	7.833496e-01	0.106	0	0
Removal of the Flap Intermediate from the C-strand	R-HSA-174437	7.875330e-01	0.104	0	0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	R-HSA-190840	7.875330e-01	0.104	0	0
Synthesis of PIPs at the late endosome membrane	R-HSA-1660517	7.875330e-01	0.104	0	0
Glycogen storage diseases	R-HSA-3229121	7.875330e-01	0.104	0	0
Elevation of cytosolic Ca2+ levels	R-HSA-139853	7.875330e-01	0.104	0	0
Regulation of NPAS4 gene expression	R-HSA-9768759	7.875330e-01	0.104	0	0
Replication of the SARS-CoV-2 genome	R-HSA-9694686	7.875330e-01	0.104	0	0
Developmental Lineage of Pancreatic Ductal Cells	R-HSA-9925563	7.894783e-01	0.103	0	0
Uptake and actions of bacterial toxins	R-HSA-5339562	7.931413e-01	0.101	0	0
Regulation of Apoptosis	R-HSA-169911	7.944372e-01	0.100	0	0
Downstream signaling of activated FGFR2	R-HSA-5654696	7.944372e-01	0.100	0	0
Downstream signaling of activated FGFR1	R-HSA-5654687	7.944372e-01	0.100	0	0
Regulation of endogenous retroelements by KRAB-ZFP proteins	R-HSA-9843940	7.976303e-01	0.098	0	0
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	7.976303e-01	0.098	0	0
Extra-nuclear estrogen signaling	R-HSA-9009391	7.985104e-01	0.098	1	0
G beta:gamma signalling through PLC beta	R-HSA-418217	8.019878e-01	0.096	0	0
Transport of connexons to the plasma membrane	R-HSA-190872	8.019878e-01	0.096	0	0
Synaptic adhesion-like molecules	R-HSA-8849932	8.019878e-01	0.096	0	0
Presynaptic function of Kainate receptors	R-HSA-500657	8.019878e-01	0.096	0	0
Chaperone Mediated Autophagy	R-HSA-9613829	8.019878e-01	0.096	0	0
Platelet sensitization by LDL	R-HSA-432142	8.019878e-01	0.096	0	0
Vitamin D (calciferol) metabolism	R-HSA-196791	8.019878e-01	0.096	0	0
Regulation of PTEN stability and activity	R-HSA-8948751	8.021789e-01	0.096	0	0
Chaperonin-mediated protein folding	R-HSA-390466	8.042458e-01	0.095	0	0
Regulation of TP53 Degradation	R-HSA-6804757	8.050199e-01	0.094	0	0
Lysosome Vesicle Biogenesis	R-HSA-432720	8.050199e-01	0.094	0	0
Glycosphingolipid transport	R-HSA-9845576	8.050199e-01	0.094	0	0
Activation of NMDA receptors and postsynaptic events	R-HSA-442755	8.051683e-01	0.094	1	0
NoRC negatively regulates rRNA expression	R-HSA-427413	8.055257e-01	0.094	0	0
Hedgehog 'on' state	R-HSA-5632684	8.055257e-01	0.094	0	0
Transcriptional and post-translational regulation of MITF-M expression and activity	R-HSA-9856649	8.055257e-01	0.094	1	1
Degradation of AXIN	R-HSA-4641257	8.151151e-01	0.089	0	0
PI-3K cascade:FGFR3	R-HSA-5654710	8.154600e-01	0.089	0	0
Signaling by FGFR2 IIIa TM	R-HSA-8851708	8.154600e-01	0.089	0	0
Pyrimidine biosynthesis	R-HSA-500753	8.154600e-01	0.089	0	0
Germ layer formation at gastrulation	R-HSA-9754189	8.154600e-01	0.089	0	0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes	R-HSA-9856532	8.154600e-01	0.089	0	0
IKK complex recruitment mediated by RIP1	R-HSA-937041	8.154600e-01	0.089	0	0
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	8.154600e-01	0.089	1	1
Other interleukin signaling	R-HSA-449836	8.154600e-01	0.089	0	0
Specification of the neural plate border	R-HSA-9834899	8.154600e-01	0.089	0	0
Crosslinking of collagen fibrils	R-HSA-2243919	8.154600e-01	0.089	0	0
SARS-CoV-2 Genome Replication and Transcription	R-HSA-9694682	8.154600e-01	0.089	0	0
mRNA Splicing - Major Pathway	R-HSA-72163	8.161215e-01	0.088	0	0
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	8.246925e-01	0.084	0	0
Metabolism of nitric oxide: NOS3 activation and regulation	R-HSA-202131	8.247401e-01	0.084	0	0
RIPK1-mediated regulated necrosis	R-HSA-5213460	8.247401e-01	0.084	0	0
Transcriptional regulation of pluripotent stem cells	R-HSA-452723	8.247401e-01	0.084	0	0
Signaling by ERBB4	R-HSA-1236394	8.277163e-01	0.082	0	0
Regulation of PD-L1(CD274) translation	R-HSA-9909620	8.280163e-01	0.082	0	0
PI-3K cascade:FGFR4	R-HSA-5654720	8.280163e-01	0.082	0	0
Co-inhibition by CTLA4	R-HSA-389513	8.280163e-01	0.082	0	0
Glycogen synthesis	R-HSA-3322077	8.280163e-01	0.082	0	0
Common Pathway of Fibrin Clot Formation	R-HSA-140875	8.280163e-01	0.082	0	0
Signaling by NODAL	R-HSA-1181150	8.280163e-01	0.082	1	1
SARS-CoV Infections	R-HSA-9679506	8.322714e-01	0.080	0	0
Stabilization of p53	R-HSA-69541	8.339121e-01	0.079	0	0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	R-HSA-381771	8.339121e-01	0.079	0	0
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	R-HSA-6781827	8.346302e-01	0.079	0	0
SARS-CoV-1-host interactions	R-HSA-9692914	8.359132e-01	0.078	0	0
Nuclear events mediated by NFE2L2	R-HSA-9759194	8.360640e-01	0.078	0	0
MyD88 deficiency (TLR2/4)	R-HSA-5602498	8.397190e-01	0.076	0	0
SHC-mediated cascade:FGFR3	R-HSA-5654704	8.397190e-01	0.076	0	0
Dual incision in TC-NER	R-HSA-6782135	8.425176e-01	0.074	0	0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	R-HSA-427389	8.426482e-01	0.074	0	0
Protein folding	R-HSA-391251	8.433759e-01	0.074	0	0
Interleukin-1 family signaling	R-HSA-446652	8.438017e-01	0.074	0	0
Extension of Telomeres	R-HSA-180786	8.496727e-01	0.071	0	0
IRAK4 deficiency (TLR2/4)	R-HSA-5603041	8.506261e-01	0.070	0	0
SHC-mediated cascade:FGFR4	R-HSA-5654719	8.506261e-01	0.070	0	0
FRS-mediated FGFR3 signaling	R-HSA-5654706	8.506261e-01	0.070	0	0
Molybdenum cofactor biosynthesis	R-HSA-947581	8.506261e-01	0.070	0	0
Listeria monocytogenes entry into host cells	R-HSA-8876384	8.506261e-01	0.070	0	0
Assembly Of The HIV Virion	R-HSA-175474	8.506261e-01	0.070	0	0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	8.509652e-01	0.070	0	0
VEGFR2 mediated vascular permeability	R-HSA-5218920	8.509652e-01	0.070	0	0
SPOP-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929491	8.509652e-01	0.070	0	0
Chromatin modifications during the maternal to zygotic transition (MZT)	R-HSA-9821002	8.509652e-01	0.070	0	0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	8.509652e-01	0.070	0	0
Maturation of spike protein	R-HSA-9694548	8.509652e-01	0.070	0	0
PCP/CE pathway	R-HSA-4086400	8.539924e-01	0.069	0	0
Signaling by Retinoic Acid	R-HSA-5362517	8.565429e-01	0.067	0	0
Sphingolipid de novo biosynthesis	R-HSA-1660661	8.565429e-01	0.067	0	0
Degradation of GLI1 by the proteasome	R-HSA-5610780	8.588797e-01	0.066	0	0
Degradation of CRY and PER proteins	R-HSA-9932298	8.588797e-01	0.066	0	0
Assembly and cell surface presentation of NMDA receptors	R-HSA-9609736	8.588797e-01	0.066	0	0
Cellular response to chemical stress	R-HSA-9711123	8.589427e-01	0.066	0	0
PI-3K cascade:FGFR1	R-HSA-5654689	8.607915e-01	0.065	0	0
FGFR2 alternative splicing	R-HSA-6803529	8.607915e-01	0.065	0	0
RNA Polymerase III Transcription Initiation From Type 3 Promoter	R-HSA-76071	8.607915e-01	0.065	0	0
FRS-mediated FGFR4 signaling	R-HSA-5654712	8.607915e-01	0.065	0	0
NOTCH3 Activation and Transmission of Signal to the Nucleus	R-HSA-9013507	8.607915e-01	0.065	0	0
mRNA Splicing	R-HSA-72172	8.624565e-01	0.064	0	0
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	8.658026e-01	0.063	0	0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells	R-HSA-9927418	8.664079e-01	0.062	0	0
Incretin synthesis, secretion, and inactivation	R-HSA-400508	8.664079e-01	0.062	0	0
NCAM signaling for neurite out-growth	R-HSA-375165	8.694628e-01	0.061	1	1
Regulation of PTEN mRNA translation	R-HSA-8943723	8.702657e-01	0.060	0	0
Prefoldin mediated transfer of substrate to CCT/TriC	R-HSA-389957	8.702657e-01	0.060	0	0
Free fatty acids regulate insulin secretion	R-HSA-400451	8.702657e-01	0.060	0	0
Organic anion transport by SLCO transporters	R-HSA-879518	8.702657e-01	0.060	0	0
Formation of the ureteric bud	R-HSA-9830674	8.702657e-01	0.060	0	0
Syndecan interactions	R-HSA-3000170	8.702657e-01	0.060	0	0
COPI-mediated anterograde transport	R-HSA-6807878	8.708455e-01	0.060	0	0
Signaling by FGFR4	R-HSA-5654743	8.735657e-01	0.059	1	0
TGF-beta receptor signaling activates SMADs	R-HSA-2173789	8.735657e-01	0.059	0	0
Interferon gamma signaling	R-HSA-877300	8.738841e-01	0.059	1	1
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	8.755291e-01	0.058	0	0
Loss of Nlp from mitotic centrosomes	R-HSA-380259	8.755291e-01	0.058	0	0
TRAF6 mediated NF-kB activation	R-HSA-933542	8.790956e-01	0.056	0	0
SHC-mediated cascade:FGFR1	R-HSA-5654688	8.790956e-01	0.056	0	0
Plasma lipoprotein assembly	R-HSA-8963898	8.790956e-01	0.056	0	0
DAP12 interactions	R-HSA-2172127	8.803687e-01	0.055	0	0
Cobalamin (Cbl, vitamin B12) transport and metabolism	R-HSA-196741	8.803687e-01	0.055	0	0
Amine ligand-binding receptors	R-HSA-375280	8.803687e-01	0.055	0	0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	8.813442e-01	0.055	0	0
TP53 Regulates Metabolic Genes	R-HSA-5628897	8.856409e-01	0.053	0	0
Asymmetric localization of PCP proteins	R-HSA-4608870	8.868319e-01	0.052	0	0
Signaling by FGFR3	R-HSA-5654741	8.868319e-01	0.052	1	0
PI-3K cascade:FGFR2	R-HSA-5654695	8.873251e-01	0.052	0	0
Acyl chain remodelling of PS	R-HSA-1482801	8.873251e-01	0.052	0	0
FRS-mediated FGFR1 signaling	R-HSA-5654693	8.873251e-01	0.052	0	0
Defects in cobalamin (B12) metabolism	R-HSA-3296469	8.873251e-01	0.052	0	0
Synthesis of PIPs at the early endosome membrane	R-HSA-1660516	8.873251e-01	0.052	0	0
MicroRNA (miRNA) biogenesis	R-HSA-203927	8.873251e-01	0.052	0	0
PIWI-interacting RNA (piRNA) biogenesis	R-HSA-5601884	8.873251e-01	0.052	0	0
Formation of the nephric duct	R-HSA-9830364	8.873251e-01	0.052	0	0
AURKA Activation by TPX2	R-HSA-8854518	8.922529e-01	0.050	0	0
Formation of TC-NER Pre-Incision Complex	R-HSA-6781823	8.929701e-01	0.049	0	0
Interleukin-1 signaling	R-HSA-9020702	8.941256e-01	0.049	0	0
Synthesis of PIPs at the Golgi membrane	R-HSA-1660514	8.949949e-01	0.048	0	0
Attachment of bacteria to epithelial cells	R-HSA-9638630	8.949949e-01	0.048	0	0
Synthesis of IP2, IP, and Ins in the cytosol	R-HSA-1855183	8.949949e-01	0.048	0	0
XBP1(S) activates chaperone genes	R-HSA-381038	9.008874e-01	0.045	0	0
Cobalamin (Cbl) metabolism	R-HSA-9759218	9.021430e-01	0.045	0	0
Signaling by BMP	R-HSA-201451	9.021430e-01	0.045	0	0
SHC-mediated cascade:FGFR2	R-HSA-5654699	9.021430e-01	0.045	0	0
EPHA-mediated growth cone collapse	R-HSA-3928663	9.021430e-01	0.045	0	0
CD28 dependent PI3K/Akt signaling	R-HSA-389357	9.021430e-01	0.045	0	0
Maturation of hRSV A proteins	R-HSA-9828806	9.021430e-01	0.045	0	0
Regulated Necrosis	R-HSA-5218859	9.022535e-01	0.045	0	0
Collagen biosynthesis and modifying enzymes	R-HSA-1650814	9.022535e-01	0.045	0	0
KEAP1-NFE2L2 pathway	R-HSA-9755511	9.067894e-01	0.042	0	0
Phase 0 - rapid depolarisation	R-HSA-5576892	9.088049e-01	0.042	0	0
FRS-mediated FGFR2 signaling	R-HSA-5654700	9.088049e-01	0.042	0	0
Activation of kainate receptors upon glutamate binding	R-HSA-451326	9.088049e-01	0.042	0	0
ATF4 activates genes in response to endoplasmic reticulum stress	R-HSA-380994	9.088049e-01	0.042	0	0
Pyroptosis	R-HSA-5620971	9.088049e-01	0.042	0	0
Inflammasomes	R-HSA-622312	9.088049e-01	0.042	0	0
Recruitment of NuMA to mitotic centrosomes	R-HSA-380320	9.093000e-01	0.041	0	0
p53-Dependent G1/S DNA damage checkpoint	R-HSA-69580	9.095751e-01	0.041	0	0
p53-Dependent G1 DNA Damage Response	R-HSA-69563	9.095751e-01	0.041	0	0
Degradation of CDH1	R-HSA-9766229	9.095751e-01	0.041	0	0
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	9.102080e-01	0.041	1	0
Chromosome Maintenance	R-HSA-73886	9.123131e-01	0.040	0	0
Regulation of RAS by GAPs	R-HSA-5658442	9.145516e-01	0.039	0	0
Endosomal Sorting Complex Required For Transport (ESCRT)	R-HSA-917729	9.150137e-01	0.039	0	0
Platelet calcium homeostasis	R-HSA-418360	9.150137e-01	0.039	0	0
Nitric oxide stimulates guanylate cyclase	R-HSA-392154	9.150137e-01	0.039	0	0
Signaling by CSF3 (G-CSF)	R-HSA-9674555	9.150137e-01	0.039	0	0
Cargo trafficking to the periciliary membrane	R-HSA-5620920	9.156874e-01	0.038	0	0
Neurotransmitter release cycle	R-HSA-112310	9.170720e-01	0.038	0	0
Hedgehog ligand biogenesis	R-HSA-5358346	9.192701e-01	0.037	0	0
RNA Polymerase III Transcription Initiation	R-HSA-76046	9.208001e-01	0.036	0	0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	R-HSA-1474151	9.208001e-01	0.036	0	0
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	9.236854e-01	0.034	0	0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)	R-HSA-9931269	9.237425e-01	0.034	0	0
E3 ubiquitin ligases ubiquitinate target proteins	R-HSA-8866654	9.237425e-01	0.034	0	0
Transcriptional Regulation by NPAS4	R-HSA-9634815	9.237425e-01	0.034	1	0
IRE1alpha activates chaperones	R-HSA-381070	9.242430e-01	0.034	0	0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	R-HSA-389958	9.261928e-01	0.033	0	0
Regulation of activated PAK-2p34 by proteasome mediated degradation	R-HSA-211733	9.261928e-01	0.033	0	0
Molecules associated with elastic fibres	R-HSA-2129379	9.261928e-01	0.033	0	0
Plasma lipoprotein assembly, remodeling, and clearance	R-HSA-174824	9.276153e-01	0.033	0	0
Amino acids regulate mTORC1	R-HSA-9639288	9.279806e-01	0.032	0	0
Centrosome maturation	R-HSA-380287	9.309829e-01	0.031	0	0
Regulation of ornithine decarboxylase (ODC)	R-HSA-350562	9.312187e-01	0.031	0	0
Developmental Cell Lineages	R-HSA-9734767	9.331437e-01	0.030	0	0
RNA Polymerase I Promoter Clearance	R-HSA-73854	9.343857e-01	0.029	1	0
Parasitic Infection Pathways	R-HSA-9824443	9.350937e-01	0.029	1	0
Leishmania infection	R-HSA-9658195	9.350937e-01	0.029	1	0
COPI-independent Golgi-to-ER retrograde traffic	R-HSA-6811436	9.357979e-01	0.029	0	0
Cardiogenesis	R-HSA-9733709	9.359026e-01	0.029	0	0
DDX58/IFIH1-mediated induction of interferon-alpha/beta	R-HSA-168928	9.369346e-01	0.028	0	0
Signaling by FGFR1	R-HSA-5654736	9.393981e-01	0.027	1	0
Ion homeostasis	R-HSA-5578775	9.393981e-01	0.027	0	0
Acyl chain remodelling of PC	R-HSA-1482788	9.402678e-01	0.027	0	0
Vpu mediated degradation of CD4	R-HSA-180534	9.402678e-01	0.027	0	0
Miscellaneous transport and binding events	R-HSA-5223345	9.402678e-01	0.027	0	0
Viral Infection Pathways	R-HSA-9824446	9.402762e-01	0.027	0	0
RNA Polymerase I Transcription	R-HSA-73864	9.407315e-01	0.027	1	0
Cholesterol biosynthesis	R-HSA-191273	9.407315e-01	0.027	0	0
CLEC7A (Dectin-1) signaling	R-HSA-5607764	9.425276e-01	0.026	0	0
Reproduction	R-HSA-1474165	9.433341e-01	0.025	0	0
eNOS activation	R-HSA-203615	9.443359e-01	0.025	0	0
Gap junction assembly	R-HSA-190861	9.443359e-01	0.025	0	0
Ubiquitin-dependent degradation of Cyclin D	R-HSA-75815	9.443359e-01	0.025	0	0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	R-HSA-110328	9.443359e-01	0.025	0	0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	R-HSA-6814122	9.443359e-01	0.025	0	0
Regulation of TLR by endogenous ligand	R-HSA-5686938	9.443359e-01	0.025	0	0
NPAS4 regulates expression of target genes	R-HSA-9768919	9.443359e-01	0.025	1	1
Signaling by FGFR2	R-HSA-5654738	9.465047e-01	0.024	1	0
PKR-mediated signaling	R-HSA-9833482	9.465047e-01	0.024	0	0
Transport to the Golgi and subsequent modification	R-HSA-948021	9.472644e-01	0.024	0	0
Post-translational protein phosphorylation	R-HSA-8957275	9.476644e-01	0.023	0	0
Degradation of the extracellular matrix	R-HSA-1474228	9.477816e-01	0.023	0	0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	R-HSA-8854050	9.481273e-01	0.023	0	0
SCF-beta-TrCP mediated degradation of Emi1	R-HSA-174113	9.481273e-01	0.023	0	0
Acyl chain remodelling of PE	R-HSA-1482839	9.481273e-01	0.023	0	0
Defects in vitamin and cofactor metabolism	R-HSA-3296482	9.481273e-01	0.023	0	0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	R-HSA-9860927	9.481273e-01	0.023	0	0
Transferrin endocytosis and recycling	R-HSA-917977	9.481273e-01	0.023	0	0
PERK regulates gene expression	R-HSA-381042	9.481273e-01	0.023	0	0
Amyloid fiber formation	R-HSA-977225	9.491910e-01	0.023	0	0
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	9.498856e-01	0.022	0	0
Potential therapeutics for SARS	R-HSA-9679191	9.502363e-01	0.022	0	0
HSF1 activation	R-HSA-3371511	9.516606e-01	0.022	0	0
PRC2 methylates histones and DNA	R-HSA-212300	9.516606e-01	0.022	0	0
Vif-mediated degradation of APOBEC3G	R-HSA-180585	9.516606e-01	0.022	0	0
AUF1 (hnRNP D0) binds and destabilizes mRNA	R-HSA-450408	9.516606e-01	0.022	0	0
GPVI-mediated activation cascade	R-HSA-114604	9.516606e-01	0.022	0	0
Formation of Fibrin Clot (Clotting Cascade)	R-HSA-140877	9.516606e-01	0.022	0	0
FGFR2 mutant receptor activation	R-HSA-1839126	9.516606e-01	0.022	0	0
Platelet activation, signaling and aggregation	R-HSA-76002	9.518491e-01	0.021	1	0
Kinesins	R-HSA-983189	9.519689e-01	0.021	0	0
Hedgehog 'off' state	R-HSA-5610787	9.523774e-01	0.021	0	0
Endogenous sterols	R-HSA-211976	9.546985e-01	0.020	0	0
Degradation of DVL	R-HSA-4641258	9.549534e-01	0.020	0	0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	R-HSA-9762114	9.549534e-01	0.020	0	0
NCAM1 interactions	R-HSA-419037	9.549534e-01	0.020	0	0
SLC-mediated transport of organic cations	R-HSA-549127	9.549534e-01	0.020	0	0
C-type lectin receptors (CLRs)	R-HSA-5621481	9.563840e-01	0.019	0	0
Phospholipid metabolism	R-HSA-1483257	9.569581e-01	0.019	0	0
The role of GTSE1 in G2/M progression after G2 checkpoint	R-HSA-8852276	9.572794e-01	0.019	0	0
Elastic fibre formation	R-HSA-1566948	9.580221e-01	0.019	0	0
Biofilm formation	R-HSA-9931953	9.580221e-01	0.019	0	0
Purine salvage	R-HSA-74217	9.580221e-01	0.019	0	0
SLC-mediated transport of inorganic anions	R-HSA-9958790	9.580221e-01	0.019	0	0
G1/S DNA Damage Checkpoints	R-HSA-69615	9.597191e-01	0.018	0	0
Response of EIF2AK4 (GCN2) to amino acid deficiency	R-HSA-9633012	9.606525e-01	0.017	0	0
Opioid Signalling	R-HSA-111885	9.606525e-01	0.017	0	0
Regulation of PD-L1(CD274) Post-translational modification	R-HSA-9909615	9.608341e-01	0.017	0	0
Cross-presentation of soluble exogenous antigens (endosomes)	R-HSA-1236978	9.608820e-01	0.017	0	0
GSK3B-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929356	9.608820e-01	0.017	0	0
Respiratory syncytial virus (RSV) genome replication, transcription and translation	R-HSA-9820965	9.608820e-01	0.017	0	0
Disorders of transmembrane transporters	R-HSA-5619115	9.628188e-01	0.016	0	0
Glycogen metabolism	R-HSA-8982491	9.635471e-01	0.016	0	0
Diseases of Immune System	R-HSA-5260271	9.635471e-01	0.016	0	0
Diseases associated with the TLR signaling cascade	R-HSA-5602358	9.635471e-01	0.016	0	0
Negative regulation of NOTCH4 signaling	R-HSA-9604323	9.635471e-01	0.016	0	0
Generation of second messenger molecules	R-HSA-202433	9.635471e-01	0.016	0	0
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	9.637875e-01	0.016	0	0
Hh mutants are degraded by ERAD	R-HSA-5362768	9.660308e-01	0.015	0	0
NIK-->noncanonical NF-kB signaling	R-HSA-5676590	9.660308e-01	0.015	0	0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	R-HSA-193368	9.682061e-01	0.014	0	0
Intra-Golgi traffic	R-HSA-6811438	9.683455e-01	0.014	0	0
GLI3 is processed to GLI3R by the proteasome	R-HSA-5610785	9.683455e-01	0.014	0	0
Degradation of GLI2 by the proteasome	R-HSA-5610783	9.683455e-01	0.014	0	0
Downstream TCR signaling	R-HSA-202424	9.699348e-01	0.013	0	0
Base Excision Repair	R-HSA-73884	9.699348e-01	0.013	0	0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	R-HSA-3371497	9.700422e-01	0.013	0	0
Cleavage of the damaged pyrimidine	R-HSA-110329	9.705025e-01	0.013	0	0
Depyrimidination	R-HSA-73928	9.705025e-01	0.013	0	0
Platelet degranulation	R-HSA-114608	9.710791e-01	0.013	0	0
TCR signaling	R-HSA-202403	9.720074e-01	0.012	0	0
Defective pyroptosis	R-HSA-9710421	9.725127e-01	0.012	0	0
Hh mutants abrogate ligand secretion	R-HSA-5387390	9.725127e-01	0.012	0	0
SCF(Skp2)-mediated degradation of p27/p21	R-HSA-187577	9.743860e-01	0.011	0	0
Proteasome assembly	R-HSA-9907900	9.743860e-01	0.011	0	0
Synthesis of Leukotrienes (LT) and Eoxins (EX)	R-HSA-2142691	9.743860e-01	0.011	0	0
FCERI mediated MAPK activation	R-HSA-2871796	9.746384e-01	0.011	1	1
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	R-HSA-983695	9.757347e-01	0.011	0	0
Fanconi Anemia Pathway	R-HSA-6783310	9.761318e-01	0.010	0	0
Defective CFTR causes cystic fibrosis	R-HSA-5678895	9.761318e-01	0.010	0	0
Dectin-1 mediated noncanonical NF-kB signaling	R-HSA-5607761	9.761318e-01	0.010	0	0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A	R-HSA-69601	9.761318e-01	0.010	0	0
p53-Independent G1/S DNA Damage Checkpoint	R-HSA-69613	9.761318e-01	0.010	0	0
Somitogenesis	R-HSA-9824272	9.761318e-01	0.010	0	0
Cellular responses to mechanical stimuli	R-HSA-9855142	9.770361e-01	0.010	0	0
Regulation of pyruvate metabolism	R-HSA-9861718	9.777586e-01	0.010	0	0
Golgi-to-ER retrograde transport	R-HSA-8856688	9.780955e-01	0.010	0	0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	R-HSA-381426	9.781533e-01	0.010	0	0
Major pathway of rRNA processing in the nucleolus and cytosol	R-HSA-6791226	9.788323e-01	0.009	0	0
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	9.790978e-01	0.009	0	0
Retrograde transport at the Trans-Golgi-Network	R-HSA-6811440	9.792747e-01	0.009	0	0
Cilium Assembly	R-HSA-5617833	9.792917e-01	0.009	0	0
Interferon alpha/beta signaling	R-HSA-909733	9.802360e-01	0.009	0	0
Protein ubiquitination	R-HSA-8852135	9.803124e-01	0.009	0	0
COPI-dependent Golgi-to-ER retrograde traffic	R-HSA-6811434	9.804608e-01	0.009	0	0
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	9.804608e-01	0.009	0	0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	R-HSA-532668	9.820041e-01	0.008	0	0
Neurotransmitter receptors and postsynaptic signal transmission	R-HSA-112314	9.821978e-01	0.008	1	0
Signaling by FGFR	R-HSA-190236	9.824809e-01	0.008	1	0
Translation of Structural Proteins	R-HSA-9694635	9.825556e-01	0.008	0	0
SARS-CoV-1 Infection	R-HSA-9678108	9.828888e-01	0.007	0	0
Integrin cell surface interactions	R-HSA-216083	9.835821e-01	0.007	0	0
Signaling by Hedgehog	R-HSA-5358351	9.842637e-01	0.007	0	0
Meiotic recombination	R-HSA-912446	9.843743e-01	0.007	0	0
Complex IV assembly	R-HSA-9864848	9.843743e-01	0.007	0	0
Activation of NF-kappaB in B cells	R-HSA-1169091	9.843743e-01	0.007	0	0
Cellular response to starvation	R-HSA-9711097	9.844396e-01	0.007	0	0
Developmental Lineage of Pancreatic Acinar Cells	R-HSA-9925561	9.845498e-01	0.007	0	0
Unfolded Protein Response (UPR)	R-HSA-381119	9.849981e-01	0.007	0	0
RNA Polymerase I Promoter Escape	R-HSA-73772	9.854397e-01	0.006	0	0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	R-HSA-9856530	9.854619e-01	0.006	0	0
Meiotic synapsis	R-HSA-1221632	9.864326e-01	0.006	0	0
Nucleotide biosynthesis	R-HSA-8956320	9.864326e-01	0.006	0	0
Base-Excision Repair, AP Site Formation	R-HSA-73929	9.873578e-01	0.006	0	0
Response of endothelial cells to shear stress	R-HSA-9860931	9.874110e-01	0.006	0	0
Glycerophospholipid biosynthesis	R-HSA-1483206	9.878985e-01	0.005	0	0
G alpha (z) signalling events	R-HSA-418597	9.882199e-01	0.005	0	0
Meiosis	R-HSA-1500620	9.892913e-01	0.005	0	0
Platelet homeostasis	R-HSA-418346	9.893460e-01	0.005	0	0
Synthesis of PA	R-HSA-1483166	9.897720e-01	0.004	0	0
rRNA processing in the nucleus and cytosol	R-HSA-8868773	9.903038e-01	0.004	0	0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	R-HSA-72662	9.904696e-01	0.004	0	0
Early SARS-CoV-2 Infection Events	R-HSA-9772572	9.904696e-01	0.004	0	0
Stimuli-sensing channels	R-HSA-2672351	9.904732e-01	0.004	0	0
Metabolism of steroids	R-HSA-8957322	9.908886e-01	0.004	0	0
Pyruvate metabolism	R-HSA-70268	9.910959e-01	0.004	0	0
Peroxisomal protein import	R-HSA-9033241	9.911197e-01	0.004	0	0
Metabolism of polyamines	R-HSA-351202	9.917255e-01	0.004	0	0
ER-Phagosome pathway	R-HSA-1236974	9.921301e-01	0.003	0	0
Nucleotide salvage	R-HSA-8956321	9.922900e-01	0.003	0	0
Nonsense-Mediated Decay (NMD)	R-HSA-927802	9.923926e-01	0.003	0	0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	R-HSA-975957	9.923926e-01	0.003	0	0
Developmental Cell Lineages of the Exocrine Pancreas	R-HSA-9820448	9.924179e-01	0.003	0	0
Regulation of expression of SLITs and ROBOs	R-HSA-9010553	9.924179e-01	0.003	0	0
Ion transport by P-type ATPases	R-HSA-936837	9.937629e-01	0.003	0	0
Late SARS-CoV-2 Infection Events	R-HSA-9772573	9.938582e-01	0.003	0	0
FCERI mediated Ca+2 mobilization	R-HSA-2871809	9.942712e-01	0.002	0	0
Intra-Golgi and retrograde Golgi-to-ER traffic	R-HSA-6811442	9.943604e-01	0.002	0	0
tRNA modification in the nucleus and cytosol	R-HSA-6782315	9.945851e-01	0.002	0	0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	R-HSA-9954716	9.949046e-01	0.002	0	0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide	R-HSA-9954709	9.952128e-01	0.002	0	0
Transmission across Chemical Synapses	R-HSA-112315	9.953106e-01	0.002	1	0
Class I MHC mediated antigen processing & presentation	R-HSA-983169	9.959776e-01	0.002	0	0
Regulation of insulin secretion	R-HSA-422356	9.960319e-01	0.002	0	0
Metabolism of cofactors	R-HSA-8978934	9.961975e-01	0.002	0	0
ECM proteoglycans	R-HSA-3000178	9.961975e-01	0.002	0	0
Retinoid metabolism and transport	R-HSA-975634	9.961975e-01	0.002	0	0
Synthesis of bile acids and bile salts	R-HSA-192105	9.962731e-01	0.002	0	0
Interconversion of nucleotide di- and triphosphates	R-HSA-499943	9.964570e-01	0.002	0	0
ABC-family proteins mediated transport	R-HSA-382556	9.964998e-01	0.002	0	0
Diseases of carbohydrate metabolism	R-HSA-5663084	9.966989e-01	0.001	0	0
ROS and RNS production in phagocytes	R-HSA-1222556	9.969243e-01	0.001	0	0
Iron uptake and transport	R-HSA-917937	9.971343e-01	0.001	0	0
ABC transporter disorders	R-HSA-5619084	9.976822e-01	0.001	0	0
SLC-mediated transport of organic anions	R-HSA-9955298	9.976822e-01	0.001	0	0
SRP-dependent cotranslational protein targeting to membrane	R-HSA-1799339	9.978866e-01	0.001	0	0
Antigen processing-Cross presentation	R-HSA-1236975	9.980163e-01	0.001	0	0
Metabolism of fat-soluble vitamins	R-HSA-6806667	9.981254e-01	0.001	0	0
Bile acid and bile salt metabolism	R-HSA-194068	9.982526e-01	0.001	0	0
TNFR2 non-canonical NF-kB pathway	R-HSA-5668541	9.983728e-01	0.001	0	0
Neuronal System	R-HSA-112316	9.985766e-01	0.001	1	0
Integration of energy metabolism	R-HSA-163685	9.985778e-01	0.001	0	0
Ribosome-associated quality control	R-HSA-9948299	9.987364e-01	0.001	0	0
rRNA processing	R-HSA-72312	9.988217e-01	0.001	0	0
Peptide chain elongation	R-HSA-156902	9.989358e-01	0.000	0	0
Eukaryotic Translation Initiation	R-HSA-72613	9.989505e-01	0.000	0	0
Cap-dependent Translation Initiation	R-HSA-72737	9.989505e-01	0.000	0	0
Adaptive Immune System	R-HSA-1280218	9.990015e-01	0.000	0	0
Peptide hormone metabolism	R-HSA-2980736	9.990155e-01	0.000	0	0
Class B/2 (Secretin family receptors)	R-HSA-373080	9.990763e-01	0.000	0	0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	R-HSA-9954714	9.991394e-01	0.000	0	0
FCERI mediated NF-kB activation	R-HSA-2871837	9.991664e-01	0.000	0	0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	R-HSA-975956	9.991982e-01	0.000	0	0
Eukaryotic Translation Elongation	R-HSA-156842	9.992530e-01	0.000	0	0
G alpha (q) signalling events	R-HSA-416476	9.992711e-01	0.000	1	0
Neddylation	R-HSA-8951664	9.993481e-01	0.000	0	0
Eukaryotic Translation Termination	R-HSA-72764	9.994373e-01	0.000	0	0
Formation of a pool of free 40S subunits	R-HSA-72689	9.994373e-01	0.000	0	0
Potassium Channels	R-HSA-1296071	9.994758e-01	0.000	0	0
Selenocysteine synthesis	R-HSA-2408557	9.996321e-01	0.000	0	0
Cardiac conduction	R-HSA-5576891	9.996485e-01	0.000	0	0
Viral mRNA Translation	R-HSA-192823	9.996807e-01	0.000	0	0
Post-translational protein modification	R-HSA-597592	9.996866e-01	0.000	0	0
Cell surface interactions at the vascular wall	R-HSA-202733	9.997182e-01	0.000	0	0
Ion channel transport	R-HSA-983712	9.997326e-01	0.000	0	0
Infectious disease	R-HSA-5663205	9.997848e-01	0.000	1	0
GTP hydrolysis and joining of the 60S ribosomal subunit	R-HSA-72706	9.997913e-01	0.000	0	0
L13a-mediated translational silencing of Ceruloplasmin expression	R-HSA-156827	9.997913e-01	0.000	0	0
Hemostasis	R-HSA-109582	9.998020e-01	0.000	1	0
Antimicrobial peptides	R-HSA-6803157	9.998313e-01	0.000	0	0
Role of phospholipids in phagocytosis	R-HSA-2029485	9.998898e-01	0.000	0	0
Disease	R-HSA-1643685	9.998986e-01	0.000	1	0
Formation of the cornified envelope	R-HSA-6809371	9.999418e-01	0.000	0	0
Metabolism of carbohydrates and carbohydrate derivatives	R-HSA-71387	9.999600e-01	0.000	0	0
Nucleotide catabolism	R-HSA-8956319	9.999620e-01	0.000	0	0
Cytochrome P450 - arranged by substrate type	R-HSA-211897	9.999708e-01	0.000	0	0
Sphingolipid metabolism	R-HSA-428157	9.999762e-01	0.000	0	0
Metabolism of nucleotides	R-HSA-15869	9.999843e-01	0.000	0	0
Visual phototransduction	R-HSA-2187338	9.999914e-01	0.000	0	0
Asparagine N-linked glycosylation	R-HSA-446203	9.999919e-01	0.000	0	0
Arachidonate metabolism	R-HSA-2142753	9.999940e-01	0.000	0	0
Protein localization	R-HSA-9609507	9.999944e-01	0.000	0	0
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	9.999964e-01	0.000	0	0
Immune System	R-HSA-168256	9.999965e-01	0.000	1	0
Innate Immune System	R-HSA-168249	9.999973e-01	0.000	1	0
Selenoamino acid metabolism	R-HSA-2408522	9.999974e-01	0.000	0	0
GPCR downstream signalling	R-HSA-388396	9.999982e-01	0.000	1	0
G alpha (s) signalling events	R-HSA-418555	9.999986e-01	0.000	0	0
Neutrophil degranulation	R-HSA-6798695	9.999986e-01	0.000	0	0
Anti-inflammatory response favouring Leishmania parasite infection	R-HSA-9662851	9.999987e-01	0.000	0	0
Leishmania parasite growth and survival	R-HSA-9664433	9.999987e-01	0.000	0	0
Respiratory electron transport	R-HSA-611105	9.999991e-01	0.000	0	0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	R-HSA-198933	9.999996e-01	0.000	0	0
Infection with Enterobacteria	R-HSA-9640148	9.999999e-01	0.000	0	0
Signaling by GPCR	R-HSA-372790	9.999999e-01	0.000	1	0
Keratinization	R-HSA-6805567	9.999999e-01	0.000	0	0
G alpha (i) signalling events	R-HSA-418594	1.000000e+00	0.000	0	0
Phase I - Functionalization of compounds	R-HSA-211945	1.000000e+00	0.000	0	0
Bacterial Infection Pathways	R-HSA-9824439	1.000000e+00	0.000	1	0
Metabolism of vitamins and cofactors	R-HSA-196854	1.000000e+00	0.000	0	0
Aerobic respiration and respiratory electron transport	R-HSA-1428517	1.000000e+00	0.000	0	0
Translation	R-HSA-72766	1.000000e+00	0.000	0	0
SLC-mediated transmembrane transport	R-HSA-425407	1.000000e+00	0.000	0	0
Fatty acid metabolism	R-HSA-8978868	1.000000e+00	0.000	0	0
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	1.000000e+00	0.000	0	0
Metabolism of lipids	R-HSA-556833	1.000000e+00	0.000	0	0
Metabolism of proteins	R-HSA-392499	1.000000e+00	0.000	0	0
Diseases of metabolism	R-HSA-5668914	1.000000e+00	0.000	0	0
Biological oxidations	R-HSA-211859	1.000000e+00	0.000	0	0
Transport of small molecules	R-HSA-382551	1.000000e+00	0.000	0	0
GPCR ligand binding	R-HSA-500792	1.000000e+00	0.000	0	0
Metabolism	R-HSA-1430728	1.000000e+00	-0.000	0	0
Sensory Perception	R-HSA-9709957	1.000000e+00	-0.000	0	0
Metabolism of amino acids and derivatives	R-HSA-71291	1.000000e+00	-0.000	0	0
MAPK3 (ERK1) activation	R-HSA-110056	1.000000e+00	0.000	1	1
Formation of apoptosome	R-HSA-111458	1.000000e+00	0.000	1	0
Cytochrome c-mediated apoptotic response	R-HSA-111461	1.000000e+00	0.000	1	0
Apoptotic factor-mediated response	R-HSA-111471	1.000000e+00	0.000	1	0
Spry regulation of FGF signaling	R-HSA-1295596	1.000000e+00	0.000	1	1
Signaling by Activin	R-HSA-1502540	1.000000e+00	0.000	1	1
ERKs are inactivated	R-HSA-202670	1.000000e+00	0.000	1	1
RSK activation	R-HSA-444257	1.000000e+00	0.000	1	1
Thrombin signalling through proteinase activated receptors (PARs)	R-HSA-456926	1.000000e+00	0.000	1	1
Negative regulation of FGFR1 signaling	R-HSA-5654726	1.000000e+00	0.000	1	1
Negative regulation of FGFR2 signaling	R-HSA-5654727	1.000000e+00	0.000	1	1
Negative regulation of FGFR3 signaling	R-HSA-5654732	1.000000e+00	0.000	1	1
Negative regulation of FGFR4 signaling	R-HSA-5654733	1.000000e+00	0.000	1	1
RNA Polymerase I Promoter Opening	R-HSA-73728	1.000000e+00	0.000	1	1
Advanced glycosylation endproduct receptor signaling	R-HSA-879415	1.000000e+00	0.000	1	1
Regulation of the apoptosome activity	R-HSA-9627069	1.000000e+00	0.000	1	1
Suppression of apoptosis	R-HSA-9635465	1.000000e+00	0.000	1	1
Infection with Mycobacterium tuberculosis	R-HSA-9635486	1.000000e+00	0.000	1	0
Response of Mtb to phagocytosis	R-HSA-9637690	1.000000e+00	0.000	1	0
Signaling by MAP2K mutants	R-HSA-9652169	1.000000e+00	0.000	1	1