EPHA4
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
Y Sites Probabilities
Log-Odds: Y Sites / Y Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0MZ66 | Y24 | Sugiyama | SHTN1 KIAA1598 | sDEEKQLQLITsLKEQAIGEyEDLRAENQKTKEKCDKIRQE |
| A5A3E0 | Y1062 | Sugiyama | POTEF A26C1B | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______ |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| A6NEC2 | Y173 | Sugiyama | NPEPPSL1 | NDKMKGFYRSKYTTPSGEVRyAAVTQFEATDARRAFPCWDE |
| A6NMY6 | Y235 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | sIMTERSVPHLQKVFDRYKsysPyDMLEsIRKEVKGDLENA |
| A6NMY6 | Y238 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | TERSVPHLQKVFDRYKsysPyDMLEsIRKEVKGDLENAFLN |
| O00116 | Y645 | Sugiyama | AGPS AAG5 | QWLKESIsDVGFGMLKSVKEyVDPNNIFGNRNLL_______ |
| O00170 | Y202 | Sugiyama | AIP XAP2 | IHQEGNRLYREGHVKEAAAKyyDAIACLKNLQMKEQPGSPE |
| O00170 | Y203 | Sugiyama | AIP XAP2 | HQEGNRLYREGHVKEAAAKyyDAIACLKNLQMKEQPGSPEW |
| O00401 | Y256 | Sugiyama | WASL | FDMCGIsEAQLKDRETSKVIyDFIEKTGGVEAVKNELRRQA |
| O00429 | Y266 | Sugiyama | DNM1L DLP1 DRP1 | NRSQLDINNKKSVTDsIRDEyAFLQKKYPSLANRNGTKYLA |
| O00469 | Y199 | Sugiyama | PLOD2 | IVQQWNLQDNDDDQLFyTKVyIDPLKREAINITLDHKCKIF |
| O00469 | Y444 | Sugiyama | PLOD2 | LWSNFWGALSPDGYYARsEDyVDIVQGNRVGVWNVPYMANV |
| O00469 | Y603 | Sugiyama | PLOD2 | MEHyGKWSGGKHHDsRIsGGyENVPTDDIHMKQVDLENVWL |
| O00625 | Y131 | Sugiyama | PIR | AHGLQLWVNLRSSEKMVEPQyQELKSEEIPKPSKDGVTVAV |
| O14776 | Y1074 | Sugiyama | TCERG1 CA150 TAF2S | DKRyLVLDCVPEERRKLIVAyVDDLDRRGPPPPPTASEPTR |
| O14818 | T147 | Sugiyama | PSMA7 HSPC | FGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKS |
| O14818 | T152 | Sugiyama | PSMA7 HSPC | LIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFL |
| O14818 | Y145 | Sugiyama | PSMA7 HSPC | RPFGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGA |
| O14818 | Y153 | Sugiyama | PSMA7 HSPC | IVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFLE |
| O14950 | Y156 | Sugiyama | MYL12B MRLC2 MYLC2B | DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____ |
| O14974 | Y911 | Sugiyama | PPP1R12A MBS MYPT1 | ETssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDSTD |
| O14979 | Y167 | Sugiyama | HNRNPDL HNRPDL JKTBP | DGKMFIGGLSWDTsKKDLtEyLSRFGEVVDCtIKTDPVTGR |
| O14980 | Y469 | Sugiyama | XPO1 CRM1 | DsINLyKNMRETLVyLTHLDyVDTERIMTEKLHNQVNGTEW |
| O15230 | Y81 | Sugiyama | LAMA5 KIAA0533 KIAA1907 | SATCGEEAPARGSPRPTEDLyCKLVGGPVAGGDPNQTIRGQ |
| O15371 | Y50 | Sugiyama | EIF3D EIF3S7 | yQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQYA |
| O43390 | Y376 | Sugiyama | HNRNPR HNRPR | ILEKSFSEFGKLERVKKLKDyAFVHFEDRGAAVKAMDEMNG |
| O43707 | Y212 | Sugiyama | ACTN4 | WKDGLAFNALIHRHRPELIEyDKLRKDDPVTNLNNAFEVAE |
| O43707 | Y441 | Sugiyama | ACTN4 | KAsIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEs |
| O43707 | Y727 | Sugiyama | ACTN4 | LEQQHQLIQEALIFDNKHtNytMEHIRVGWEQLLTTIARTI |
| O43707 | Y878 | Sugiyama | ACTN4 | DKNFITAEELRRELPPDQAEyCIARMAPyQGPDAVPGALDy |
| O43852 | Y106 | Sugiyama | CALU | GFVtVDELKDWIKFAQKRWIyEDVERQWKGHDLNEDGLVsW |
| O43852 | Y129 | Sugiyama | CALU | VERQWKGHDLNEDGLVsWEEyKNATYGYVLDDPDPDDGFNY |
| O43852 | Y185 | Sugiyama | CALU | KDGDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNAD |
| O43852 | Y187 | Sugiyama | CALU | GDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNADGF |
| O43852 | Y263 | Sugiyama | CALU | KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG |
| O43852 | Y275 | Sugiyama | CALU | KDWILPsDyDHAEAEARHLVyEsDQNKDGKLTKEEIVDKyD |
| O43852 | Y47 | Sugiyama | CALU | RVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQLtPE |
| O60343 | Y879 | Sugiyama | TBC1D4 AS160 KIAA0603 | ENQKLEASRDELQSRKVKLDyEEVGACQKEVLITWDKKLLN |
| O60361 | Y136 | Sugiyama | NME2P1 | SLRFKPEELVDYKSCAHDWVyE___________________ |
| O60488 | Y582 | Sugiyama | ACSL4 ACS4 FACL4 LACS4 | DGCLQIIDRKKDLVKLQAGEyVsLGKVEAALKNCPLIDNIC |
| O60506 | Y373 | Sugiyama | SYNCRIP HNRPQ NSAP1 | ILEKAFsQFGKLERVKKLKDyAFIHFDERDGAVKAMEEMNG |
| O60664 | Y95 | Sugiyama | PLIN3 M6PRBP1 TIP47 | VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE |
| O60716 | S859 | Sugiyama | CTNND1 KIAA0384 | LEKEGWKKsDFQVNLNNAsRsQssHsyDDstLPLIDRNQKs |
| O60814 | Y38 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK |
| O60814 | Y41 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| O60814 | Y43 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| O60869 | Y109 | Sugiyama | EDF1 | GLtQKDLATKINEKPQVIADyESGRAIPNNQVLGKIERAIG |
| O75116 | Y936 | Sugiyama | ROCK2 KIAA0619 | EITLTKADSEQLARsIAEEQysDLEKEKIMKELEIKEMMAR |
| O75131 | Y162 | Sugiyama | CPNE3 CPN3 KIAA0636 | LFEMEARKLDNKDLFGKSDPyLEFHKQTSDGNWLMVHRTEV |
| O75223 | Y156 | Sugiyama | GGCT C7orf24 CRF21 | sPQYKKIICMGAKENGLPLEyQEKLKAIEPNDytGKVsEEI |
| O75347 | Y75 | Sugiyama | TBCA | EILQEsRMMIPDCQRRLEAAyLDLQRILENEKDLEEAEEyK |
| O75369 | T1575 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | QITDQEGKPKRAIVHDNKDGtyAVtyIPDKtGRYMIGVTYG |
| O75369 | Y902 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | VQFNsPLPGDAVKDLDIIDNyDysHtVKYtPtQQGNMQVLV |
| O75369 | Y904 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | FNsPLPGDAVKDLDIIDNyDysHtVKYtPtQQGNMQVLVTY |
| O75817 | Y38 | Sugiyama | POP7 RPP20 | VEytLRKRLPSRLPRRPNDIyVNMKTDFKAQLARCQKLLDG |
| O95340 | Y182 | Sugiyama | PAPSS2 ATPSK2 | GLYKRARAGEIKGFTGIDsDyEKPEtPERVLKTNLSTVSDC |
| O95347 | Y938 | Sugiyama | SMC2 CAPE SMC2L1 PRO0324 | SKHKREAEDGAAKVSKMLKDyDWINAERHLFGQPNSAYDFK |
| O95573 | Y591 | Sugiyama | ACSL3 ACS3 FACL3 LACS3 | DGCLKIIDRKKDLVKLQAGEyVsLGKVEAALKNLPLVDNIC |
| O95757 | Y627 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | MIMQDKLEKERNDAKNAVEEyVyDFRDRLGtVYEKFITPED |
| O95757 | Y629 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | MQDKLEKERNDAKNAVEEyVyDFRDRLGtVYEKFITPEDLS |
| O95834 | Y352 | Sugiyama | EML2 EMAP2 EMAPL2 | EVPEDFGPVRTVAEGHGDtLyVGtTRNSILQGSVHTGFSLL |
| O96019 | Y69 | Sugiyama | ACTL6A BAF53 BAF53A INO80K | DGsTLMEIDGDKGKQGGPtyyIDtNALRVPRENMEAIsPLK |
| P00338 | Y239 | Sugiyama | LDHA PIG19 | GtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVADL |
| P00374 | Y183 | Sugiyama | DHFR | YPGVLsDVQEEKGIKYKFEVyEKND________________ |
| P00491 | Y249 | Sugiyama | PNP NP | RHCGLRVFGFSLITNKVIMDyESLEKANHEEVLAAGKQAAQ |
| P00558 | Y161 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL |
| P00966 | Y163 | Sugiyama | ASS1 ASS | APWRMPEFYNRFKGRNDLMEyAKQHGIPIPVtPKNPWSMDE |
| P02786 | Y123 | Sugiyama | TFRC | GTEsPVREEPGEDFPAARRLyWDDLKRKLsEKLDstDFTGt |
| P02786 | Y152 | Sugiyama | TFRC | sEKLDstDFTGtIKLLNENsyVPREAGsQKDENLALyVENQ |
| P02786 | Y168 | Sugiyama | TFRC | NENsyVPREAGsQKDENLALyVENQFREFKLSKVWRDQHFV |
| P04080 | Y97 | Sugiyama | CSTB CST6 STFB | NKPLtLsNyQTNKAKHDELtyF___________________ |
| P04181 | Y55 | Sugiyama | OAT | QGPPtSDDIFEREyKyGAHNyHPLPVALERGKGIyLWDVEG |
| P05198 | Y150 | Sugiyama | EIF2S1 EIF2A | LFQRTAWVFDDKyKRPGyGAyDAFKHAVsDPsILDsLDLNE |
| P05783 | Y363 | Sugiyama | KRT18 CYK18 PIG46 | LHLESELAQTRAEGQRQAQEyEALLNIKVKLEAEIATYRRL |
| P05787 | Y204 | Sugiyama | KRT8 CYK8 | NKRTEMENEFVLIKKDVDEAyMNKVELESRLEGLTDEINFL |
| P05787 | Y286 | Sugiyama | KRT8 CYK8 | QyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTE |
| P06493 | Y15 | Sugiyama | CDK1 CDC2 CDC28A CDKN1 P34CDC2 | ______MEDyTKIEKIGEGtyGVVyKGRHKTTGQVVAMKKI |
| P06733 | S268 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | ASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyP |
| P06733 | S272 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI |
| P06733 | Y131 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | ILGVsLAVCKAGAVEKGVPLyRHIADLAGNsEVILPVPAFN |
| P06733 | Y189 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | MILPVGAANFREAMRIGAEVyHNLKNVIKEKyGKDAtNVGD |
| P06733 | Y270 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV |
| P06733 | Y280 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD |
| P06733 | Y44 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK |
| P06899 | Y41 | Sugiyama | H2BC11 H2BFR HIST1H2BJ | KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMG |
| P06899 | Y43 | Sugiyama | H2BC11 H2BFR HIST1H2BJ | QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMGIM |
| P07195 | Y240 | Sugiyama | LDHB | GTDNDSENWKEVHKMVVEsAyEVIKLKGYTNWAIGLSVADL |
| P07195 | Y84 | Sugiyama | LDHB | MDLQHGsLFLQtPKIVADKDysVtANSKIVVVtAGVRQQEG |
| P07205 | Y161 | Sugiyama | PGK2 PGKB | KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL |
| P07205 | Y196 | Sugiyama | PGK2 PGKB | MVGVNLPHKASGFLMKKELDyFAKALENPVRPFLAILGGAK |
| P07237 | Y94 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07355 | Y188 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT |
| P07355 | Y235 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sIMTERSVPHLQKVFDRYKsysPyDMLEsIRKEVKGDLENA |
| P07355 | Y238 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | TERSVPHLQKVFDRYKsysPyDMLEsIRKEVKGDLENAFLN |
| P07384 | Y37 | Sugiyama | CAPN1 CANPL1 PIG30 | QVQKQRARELGLGRHENAIKyLGQDyEQLRVRCLQSGTLFR |
| P07384 | Y42 | Sugiyama | CAPN1 CANPL1 PIG30 | RARELGLGRHENAIKyLGQDyEQLRVRCLQSGTLFRDEAFP |
| P07711 | Y112 | Sugiyama | CTSL CTSL1 | MNGFQNRKPRKGKVFQEPLFyEAPRSVDWREKGyVTPVKNQ |
| P07737 | Y129 | Sugiyama | PFN1 | tLVLLMGKEGVHGGLINKKCyEMAsHLRRsQY_________ |
| P07741 | Y60 | Sugiyama | APRT | RAAIGLLARHLKATHGGRIDyIAGLDsRGFLFGPSLAQELG |
| P07814 | Y1504 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | KPLCELQPGAKCVCGKNPAKyytLFGRsy____________ |
| P07814 | Y1505 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PLCELQPGAKCVCGKNPAKyytLFGRsy_____________ |
| P07814 | Y827 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK |
| P07858 | Y244 | Sugiyama | CTSB CPSB | HYGYNSYSVSNSEKDIMAEIyKNGPVEGAFSVYSDFLLYKS |
| P07900 | S63 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN |
| P07900 | Y284 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI |
| P07900 | Y492 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DEMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLR |
| P07900 | Y493 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | EMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLRK |
| P07900 | Y61 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KEIFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLI |
| P07942 | Y1002 | Sugiyama | LAMB1 | IDTTDPEACDKETGRCLKCLyHtEGEHCQFCRFGyyGDALQ |
| P07942 | Y1017 | Sugiyama | LAMB1 | CLKCLyHtEGEHCQFCRFGyyGDALQQDCRKCVCNYLGTVQ |
| P07954 | Y110 | Sugiyama | FH | tPVIKAFGILKRAAAEVNQDyGLDPKIANAIMKAADEVAEG |
| P08238 | S58 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| P08238 | Y276 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI |
| P08238 | Y301 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF |
| P08238 | Y305 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG |
| P08238 | Y430 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KKCLELFsELAEDKENyKKFyEAFSKNLKLGIHEDstNRRR |
| P08238 | Y472 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | sELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKE |
| P08238 | Y484 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR |
| P08238 | Y485 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVRK |
| P08238 | Y56 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEIFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDII |
| P08238 | Y619 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR |
| P08621 | Y38 | Sugiyama | SNRNP70 RNPU1Z RPU1 SNRP70 U1AP1 | PIPYLPPLEKLPHEKHHNQPyCGIAPYIREFEDPRDAPPPT |
| P08708 | Y84 | Sugiyama | RPS17 RPS17L | GPVRGISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKE |
| P08758 | Y91 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | SELTGKFEKLIVALMKPSRLyDAyELKHALKGAGTNEKVLt |
| P08758 | Y94 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | TGKFEKLIVALMKPSRLyDAyELKHALKGAGTNEKVLtEII |
| P08842 | Y524 | Sugiyama | STS ARSC1 | DISKDPRERNPLTPASEPRFyEILKVMQEAADRHTQTLPEV |
| P09104 | Y44 | Sugiyama | ENO2 | LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK |
| P09874 | Y794 | Sugiyama | PARP1 ADPRT PPOL | AySLLRGGsDDssKDPIDVNyEKLKTDIKVVDRDSEEAEII |
| P09923 | Y188 | Sugiyama | ALPI | TRVQHAsPAGtyAHtVNRNWysDADMPASARQEGCQDIATQ |
| P09972 | Y358 | Sugiyama | ALDOC ALDC | AAQGKYEGSGEDGGAAAQsLyIANHAY______________ |
| P0CG38 | Y1062 | Sugiyama | POTEI | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P0CG39 | Y1025 | Sugiyama | POTEJ | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P10809 | Y223 | Sugiyama | HSPD1 HSP60 | DGKtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAy |
| P10809 | Y227 | Sugiyama | HSPD1 HSP60 | LNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLs |
| P10809 | Y243 | Sugiyama | HSPD1 HSP60 | yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P11142 | Y545 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | YKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKINDE |
| P11233 | Y153 | Sugiyama | RALA RAL | DKRQVsVEEAKNRAEQWNVNyVETSAKTRANVDKVFFDLMR |
| P11310 | Y67 | Sugiyama | ACADM | EFQATARKFAREEIIPVAAEyDKTGEyPVPLIRRAWELGLM |
| P11940 | Y194 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF |
| P11940 | Y297 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | KRKFEQMKQDRITRyQGVNLyVKNLDDGIDDERLRKEFsPF |
| P12268 | Y509 | Sugiyama | IMPDH2 IMPD2 | KFEKRtssAQVEGGVHsLHsyEKRLF_______________ |
| P12277 | Y125 | Sugiyama | CKB CKBB | EHKTDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPH |
| P12277 | Y39 | Sugiyama | CKB CKBB | EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT |
| P12814 | Y193 | Sugiyama | ACTN1 | WKDGLGFCALIHRHRPELIDyGKLRKDDPLTNLNTAFDVAE |
| P12814 | Y422 | Sugiyama | ACTN1 | KAsIHEAWtDGKEAMLRQKDyEtAtLsEIKALLKKHEAFEs |
| P12814 | Y708 | Sugiyama | ACTN1 | LEGDHQLIQEALIFDNKHtNytMEHIRVGWEQLLTTIARTI |
| P12814 | Y842 | Sugiyama | ACTN1 | DTDTADQVMASFKILAGDKNyITMDELRRELPPDQAEyCIA |
| P12814 | Y859 | Sugiyama | ACTN1 | DKNyITMDELRRELPPDQAEyCIARMAPYTGPDSVPGALDY |
| P13639 | Y373 | Sugiyama | EEF2 EF2 | MITIHLPSPVTAQKyRCELLyEGPPDDEAAMGIKsCDPKGP |
| P13639 | Y634 | Sugiyama | EEF2 EF2 | AEDIDKGEVsARQELKQRARyLAEKyEWDVAEARKIWCFGP |
| P13639 | Y639 | Sugiyama | EEF2 EF2 | KGEVsARQELKQRARyLAEKyEWDVAEARKIWCFGPDGTGP |
| P13639 | Y730 | Sugiyama | EEF2 EF2 | HADAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQ |
| P13667 | Y392 | Sugiyama | PDIA4 ERP70 ERP72 | HMMDVQGstQDsAIKDFVLKyALPLVGHRKVSNDAKRYTRR |
| P13674 | Y282 | Sugiyama | P4HA1 P4HA | ASDDQSDQKTTPKKKGVAVDyLPERQKyEMLCRGEGIKMTP |
| P13929 | Y131 | Sugiyama | ENO3 | ILGVSLAVCKAGAAEKGVPLyRHIADLAGNPDLILPVPAFN |
| P13929 | Y44 | Sugiyama | ENO3 | LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK |
| P14314 | Y106 | Sugiyama | PRKCSH G19P1 | yIPSNRVNDGVCDCCDGtDEyNsGVICENtCKEKGRKEREs |
| P14324 | Y349 | Sugiyama | FDPS FPS KIAA1293 | QDNKCSWLVVQCLQRATPEQyQILKENYGQKEAEKVARVKA |
| P14618 | Y148 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | GtAEVELKKGATLKITLDNAyMEKCDENILWLDYKNICKVV |
| P14618 | Y83 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | EMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPI |
| P14625 | Y258 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | GNTLGRGTTITLVLKEEAsDyLELDTIKNLVKKYSQFINFP |
| P14625 | Y401 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | VTFKSILFVPTSAPRGLFDEyGsKKSDYIKLYVRRVFITDD |
| P14625 | Y527 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | AKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAGsSRK |
| P14625 | Y539 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | tDItsLDQyVERMKEKQDKIyFMAGsSRKEAEssPFVERLL |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14649 | Y143 | Sugiyama | MYL6B MLC1SA | DFETFLPMLQAVAKNRGQGTyEDyLEGFRVFDKEGNGKVMG |
| P14649 | Y86 | Sugiyama | MYL6B MLC1SA | LEEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVL |
| P14854 | Y34 | Sugiyama | COX6B1 COX6B | TAPFDSRFPNQNQTRNCWQNyLDFHRCQKAMTAKGGDIsVC |
| P15259 | Y92 | Sugiyama | PGAM2 PGAMM | DGTDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQV |
| P15880 | Y266 | Sugiyama | RPS2 RPS4 | KTysyLtPDLWKEtVFtKsPyQEFtDHLVKtHtRVsVQRtQ |
| P17066 | Y43 | Sugiyama | HSPA6 HSP70B' | FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL |
| P17812 | Y567 | Sugiyama | CTPS1 CTPS | SVGRLSHYLQKGCRLsPRDtysDRsGsssPDsEItELKFPs |
| P17844 | Y416 | Sugiyama | DDX5 G17P1 HELR HLR1 | IATDVAsRGLDVEDVKFVINyDyPNSsEDyIHRIGRTARST |
| P17844 | Y425 | Sugiyama | DDX5 G17P1 HELR HLR1 | LDVEDVKFVINyDyPNSsEDyIHRIGRTARSTKtGtAytFF |
| P17980 | Y381 | Sugiyama | PSMC3 TBP1 | ARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQCKAVCV |
| P17987 | Y545 | Sugiyama | TCP1 CCT1 CCTA | LRIDDLIKLHPESKDDKHGsyEDAVHsGALND_________ |
| P18206 | Y822 | Sugiyama | VCL | KAVAGNIsDPGLQKsFLDsGyRILGAVAKVREAFQPQEPDF |
| P18615 | Y133 | Sugiyama | NELFE RD RDBP | sIsADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEA |
| P18615 | Y302 | Sugiyama | NELFE RD RDBP | PFGNIIDLSMDPPRNCAFVTyEKMESADQAVAELNGTQVES |
| P18621 | S5 | Sugiyama | RPL17 | ________________MVRysLDPENPtKsCKSRGSNLRVH |
| P18669 | Y119 | Sugiyama | PGAM1 PGAMA CDABP0006 | NKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsKD |
| P18669 | Y133 | Sugiyama | PGAM1 PGAMA CDABP0006 | KIWRRsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsC |
| P18669 | Y142 | Sugiyama | PGAM1 PGAMA CDABP0006 | PPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIAR |
| P18669 | Y26 | Sugiyama | PGAM1 PGAMA CDABP0006 | LVLIRHGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALR |
| P18669 | Y92 | Sugiyama | PGAM1 PGAMA CDABP0006 | DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV |
| P19105 | Y155 | Sugiyama | MYL12A MLCB MRLC3 RLC | DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____ |
| P20618 | Y150 | Sugiyama | PSMB1 PSC5 | FPYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSAS |
| P20618 | Y158 | Sugiyama | PSMB1 PSC5 | IGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLD |
| P22234 | Y22 | Sugiyama | PAICS ADE2 AIRC PAIS | AtAEVLNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAG |
| P22314 | Y451 | Sugiyama | UBA1 A1S9T UBE1 | CLPEDKEVLTEDKCLQRQNRyDGQVAVFGsDLQEKLGKQKY |
| P22314 | Y60 | Sugiyama | UBA1 A1S9T UBE1 | GMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSVLVSGL |
| P22392 | Y151 | Sugiyama | NME2 NM23B | SLWFKPEELVDyKSCAHDWVyE___________________ |
| P22626 | Y336 | Sugiyama | HNRNPA2B1 HNRPA2B1 | MKsGNFGGsRNMGGPyGGGNyGPGGsGGsGGyGGRsRy___ |
| P23246 | Y488 | Sugiyama | SFPQ PSF | PMYQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQV |
| P23246 | Y490 | Sugiyama | SFPQ PSF | YQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQVEK |
| P23284 | Y47 | Sugiyama | PPIB CYPB | LPGPSAADEKKKGPKVTVKVyFDLRIGDEDVGRVIFGLFGK |
| P23434 | Y139 | Sugiyama | GCSH | EVTEINEALAENPGLVNKSCyEDGWLIKMtLsNPsELDELM |
| P23526 | Y165 | Sugiyama | AHCY SAHH | QLLPGIRGIsEEtTTGVHNLyKMMANGILKVPAINVNDsVt |
| P23526 | Y193 | Sugiyama | AHCY SAHH | LKVPAINVNDsVtKsKFDNLyGCRESLIDGIKRATDVMIAG |
| P23527 | Y41 | Sugiyama | H2BC17 H2BFH H2BFN HIST1H2BO | KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMG |
| P23527 | Y43 | Sugiyama | H2BC17 H2BFH H2BFN HIST1H2BO | QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKAMGIM |
| P23528 | Y140 | Sugiyama | CFL1 CFL | SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs |
| P23528 | Y68 | Sugiyama | CFL1 CFL | ILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAt |
| P23528 | Y82 | Sugiyama | CFL1 CFL | QtVDDPyAtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFI |
| P23528 | Y85 | Sugiyama | CFL1 CFL | DDPyAtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWA |
| P23528 | Y89 | Sugiyama | CFL1 CFL | AtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPESA |
| P23921 | Y74 | Sugiyama | RRM1 RR1 | VELDTLAAETAATLTTKHPDyAILAARIAVSNLHKETKKVF |
| P24534 | Y18 | Sugiyama | EEF1B2 EEF1B EF1B | ___MGFGDLKsPAGLQVLNDyLADKSYIEGYVPsQADVAVF |
| P24752 | Y90 | Sugiyama | ACAT1 ACAT MAT | IAIQGAIEKAGIPKEEVKEAyMGNVLQGGEGQAPTRQAVLG |
| P24941 | Y15 | Sugiyama | CDK2 CDKN2 | ______MENFQKVEKIGEGtyGVVyKARNKLTGEVVALKKI |
| P26196 | Y469 | Sugiyama | DDX6 HLR2 RCK | IEEQLGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP______ |
| P26196 | Y473 | Sugiyama | DDX6 HLR2 RCK | LGTEIKPIPsNIDKSLyVAEyHsEPVEDEKP__________ |
| P26599 | Y127 | Sugiyama | PTBP1 PTB | ANTMVNYYTSVTPVLRGQPIyIQFsNHKELKtDSSPNQARA |
| P27348 | Y149 | Sugiyama | YWHAQ | LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG |
| P27348 | Y19 | Sugiyama | YWHAQ | __MEKTELIQKAKLAEQAERyDDMAtCMKAVtEQGAELsNE |
| P27348 | Y48 | Sugiyama | YWHAQ | AVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSIEQK |
| P27540 | Y561 | Sugiyama | ARNT BHLHE2 | PLEKSDGLFAQDRDPRFsEIyHNINADQSKGISSSTVPATQ |
| P27695 | Y45 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | KSKTAAKKNDKEAAGEGPALyEDPPDQKtsPsGKPAtLKIC |
| P27797 | Y109 | Sugiyama | CALR CRTC | QTLVVQFTVKHEQNIDCGGGyVKLFPNSLDQTDMHGDSEYN |
| P27816 | Y47 | Sugiyama | MAP4 | AtLEAEAFDDVVGETVGKTDyIPLLDVDEKtGNsESKKKPC |
| P28062 | Y184 | Sugiyama | PSMB8 LMP7 PSMB5i RING10 Y2 | GMGLSMGSMICGWDKKGPGLyyVDEHGTRLSGNMFSTGSGN |
| P28062 | Y185 | Sugiyama | PSMB8 LMP7 PSMB5i RING10 Y2 | MGLSMGSMICGWDKKGPGLyyVDEHGTRLSGNMFSTGSGNT |
| P28074 | Y172 | Sugiyama | PSMB5 LMPX MB1 X | MGLSMGTMICGWDKRGPGLyyVDsEGNRISGATFSVGSGSV |
| P29320 | T780 | Sugiyama | EPHA3 ETK ETK1 HEK TYRO4 | CKVSDFGLsRVLEDDPEAAyttRGGKIPIRWTSPEAIAyRK |
| P29320 | T781 | Sugiyama | EPHA3 ETK ETK1 HEK TYRO4 | KVSDFGLsRVLEDDPEAAyttRGGKIPIRWTSPEAIAyRKF |
| P29320 | Y779 | Sugiyama | EPHA3 ETK ETK1 HEK TYRO4 | VCKVSDFGLsRVLEDDPEAAyttRGGKIPIRWTSPEAIAyR |
| P29401 | Y481 | Sugiyama | TKT | AANTKGICFIRTsRPENAIIyNNNEDFQVGQAKVVLKSKDD |
| P29692 | Y26 | Sugiyama | EEF1D EF1D | LAHEKIWFDKFKYDDAERRFyEQMNGPVAGAsRQENGAsVI |
| P30043 | S202 | Sugiyama | BLVRB FLR SCAN | GHFMLRCLttDEyDGHstyPsHQyQ________________ |
| P30043 | Y200 | Sugiyama | BLVRB FLR SCAN | DLGHFMLRCLttDEyDGHstyPsHQyQ______________ |
| P30086 | Y64 | Sugiyama | PEBP1 PBP PEBP | tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW |
| P30101 | Y115 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA |
| P30101 | Y356 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | FVMQEEFsRDGKALERFLQDyFDGNLKRyLKsEPIPESNDG |
| P30101 | Y95 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KGIVPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAy |
| P30520 | Y428 | Sugiyama | ADSS2 ADSS | WNTDISNARAFKELPVNAQNyVRFIEDELQIPVKWIGVGKs |
| P30740 | Y112 | Sugiyama | SERPINB1 ELANH2 MNEI PI2 | LYGEKTYNFLPEFLVSTQKtyGADLAsVDFQHASEDARKTI |
| P31153 | Y235 | Sugiyama | MAT2A AMS2 MATA2 | LDEMRDALKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGP |
| P31153 | Y242 | Sugiyama | MAT2A AMS2 MATA2 | LKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLt |
| P31327 | Y1450 | Sugiyama | CPS1 | GsIDLVINLPNNNTKFVHDNyVIRRTAVDSGIPLLTNFQVT |
| P31327 | Y162 | Sugiyama | CPS1 | HWLATKsLGQWLQEEKVPAIyGVDtRMLTKIIRDKGTMLGK |
| P31943 | Y266 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst |
| P31946 | Y151 | Sugiyama | YWHAB | LsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLG |
| P31946 | Y21 | Sugiyama | YWHAB | MTMDKsELVQKAKLAEQAERyDDMAAAMKAVtEQGHELsNE |
| P31946 | Y50 | Sugiyama | YWHAB | AVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK |
| P31947 | Y151 | Sugiyama | SFN HME1 | LAEVATGDDKKRIIDSARsAyQEAMDISKKEMPPTNPIRLG |
| P31947 | Y19 | Sugiyama | SFN HME1 | __MERASLIQKAKLAEQAERyEDMAAFMKGAVEKGEELsCE |
| P31947 | Y48 | Sugiyama | SFN HME1 | GAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsIEQK |
| P31948 | Y354 | Sugiyama | STIP1 | DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG |
| P32119 | Y115 | Sugiyama | PRDX2 NKEFB TDPX1 | GLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFIIDGK |
| P32929 | S61 | Sugiyama | CTH | ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA |
| P32969 | Y180 | Sugiyama | RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 | LIQQATTVKNKDIRKFLDGIyVsEKGtVQQADE________ |
| P33176 | Y516 | Sugiyama | KIF5B KNS KNS1 | EELAVNyDQKSQEVEDKTKEyELLSDELNQKsATLAsIDAE |
| P33316 | Y167 | Sugiyama | DUT | PPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDVGAG |
| P33778 | Y41 | Sugiyama | H2BC3 H2BFF HIST1H2BB | KAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKAMG |
| P33778 | Y43 | Sugiyama | H2BC3 H2BFF HIST1H2BB | QKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKAMGIM |
| P33993 | Y102 | Sugiyama | MCM7 CDC47 MCM2 | QELLPQYKEREVVNKDVLDVyIEHRLMMEQRSRDPGMVRsP |
| P34896 | Y180 | Sugiyama | SHMT1 | ISATSIFFESMPYKVNPDtGyINyDQLEENARLFHPKLIIA |
| P34896 | Y183 | Sugiyama | SHMT1 | TSIFFESMPYKVNPDtGyINyDQLEENARLFHPKLIIAGTS |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P34932 | Y30 | Sugiyama | HSPA4 APG2 HSPH2 | FQSCYVAVARAGGIETIANEysDRCtPACIsFGPKNRSIGA |
| P34932 | Y597 | Sugiyama | HSPA4 APG2 HSPH2 | VDLPIENQLLWQIDREMLNLyIENEGKMIMQDKLEKERNDA |
| P34932 | Y624 | Sugiyama | HSPA4 APG2 HSPH2 | MIMQDKLEKERNDAKNAVEEyVyEMRDKLSGEYEKFVSEDD |
| P34932 | Y626 | Sugiyama | HSPA4 APG2 HSPH2 | MQDKLEKERNDAKNAVEEyVyEMRDKLSGEYEKFVSEDDRN |
| P34932 | Y660 | Sugiyama | HSPA4 APG2 HSPH2 | VSEDDRNsFtLKLEDTENWLyEDGEDQPKQVYVDKLAELKN |
| P34932 | Y723 | Sugiyama | HSPA4 APG2 HSPH2 | GKQIQQYMKIISSFKNKEDQyDHLDAADMTKVEKSTNEAME |
| P35270 | Y259 | Sugiyama | SPR | QKLLSLLEKDEFKSGAHVDFyDK__________________ |
| P35609 | Y715 | Sugiyama | ACTN2 | LEGDHQLIQEALVFDNKHtNytMEHIRVGWELLLTTIARTI |
| P35637 | Y325 | Sugiyama | FUS TLS | FKQIGIIKTNKKTGQPMINLyTDRETGKLKGEAtVsFDDPP |
| P35637 | Y468 | Sugiyama | FUS TLS | KAPKPDGPGGGPGGsHMGGNyGDDRRGGRGGYDRGGYRGRG |
| P36578 | Y211 | Sugiyama | RPL4 RPL1 | AGKGKMRNRRRIQRRGPCIIyNEDNGIIKAFRNIPGITLLN |
| P36871 | T426 | Sugiyama | PGM1 | KQsVEDILKDHWQKYGRNFFtRyDyEEVEAEGANKMMKDLE |
| P36871 | Y353 | Sugiyama | PGM1 | RSMPTSGALDRVAsATKIALyEtPTGWKFFGNLMDASKLSL |
| P36871 | Y430 | Sugiyama | PGM1 | EDILKDHWQKYGRNFFtRyDyEEVEAEGANKMMKDLEALMF |
| P36959 | Y267 | PSP | GMPR GMPR1 | GHTECAGEVFERNGRKLKLFyGMSsDtAMNKHAGGVAEYRA |
| P37198 | Y422 | Sugiyama | NUP62 | ELEDLLsPLEELVKEQsGtIyLQHADEEREKTYKLAENIDA |
| P37268 | Y220 | Sugiyama | FDFT1 | DTERANSMGLFLQKTNIIRDyLEDQQGGREFWPQEVWSRYV |
| P37802 | Y192 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________ |
| P38646 | Y118 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK |
| P38646 | Y196 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | EtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNV |
| P39019 | Y48 | Sugiyama | RPS19 | LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P39687 | T143 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | CEVtNLNDyRENVFKLLPQLtyLDGyDRDDKEAPDsDAEGY |
| P40227 | Y109 | Sugiyama | CCT6A CCT6 CCTZ | GDGTTsNVLIIGELLKQADLyISEGLHPRIITEGFEAAKEK |
| P40261 | Y11 | Sugiyama | NNMT | __________MESGFTSKDTyLSHFNPRDYLEKYYKFGSRH |
| P41091 | Y102 | Sugiyama | EIF2S3 EIF2G | GYANAKIYKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKG |
| P41252 | Y148 | Sugiyama | IARS1 IARS | SAEWKSTVsRLGRWIDFDNDyKTLYPQFMESVWWVFKQLYD |
| P42025 | Y33 | Sugiyama | ACTR1B CTRN2 | VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALE |
| P42025 | Y38 | Sugiyama | ACTR1B CTRN2 | SGVIKAGFAGDQIPKyCFPNyVGRPKHMRVMAGALEGDLFI |
| P43243 | Y202 | Sugiyama | MATR3 KIAA0723 | RHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDD |
| P43378 | Y304 | Sugiyama | PTPN9 | HAMTIQELVDYVNARQKQGIyEEyEDIRRENPVGTFHCsMs |
| P43378 | Y307 | Sugiyama | PTPN9 | TIQELVDYVNARQKQGIyEEyEDIRRENPVGTFHCsMsPGN |
| P43490 | Y34 | Sugiyama | NAMPT PBEF PBEF1 | ATDSYKVTHYKQYPPNTSKVysyFECREKKTENSKLRKVKY |
| P46777 | Y207 | Sugiyama | RPL5 MSTP030 | sKEFNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyI |
| P46777 | Y253 | Sugiyama | RPL5 MSTP030 | PDMMEEMyKKAHAAIRENPVyEKKPKKEVKKKRWNRPKMsL |
| P46778 | Y156 | Sugiyama | RPL21 | REAHFVRTNGKEPELLEPIPyEFMA________________ |
| P46778 | Y30 | Sugiyama | RPL21 | GTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQK |
| P46940 | Y41 | Sugiyama | IQGAP1 KIAA0051 | LDNERLTAEEMDERRRQNVAyEyLCHLEEAKRWMEACLGED |
| P46940 | Y43 | Sugiyama | IQGAP1 KIAA0051 | NERLTAEEMDERRRQNVAyEyLCHLEEAKRWMEACLGEDLP |
| P47224 | Y114 | Sugiyama | RABIF MSS4 RASGRF3 | CADCEIGPIGWHCLDDKNSFyVALERVSHE___________ |
| P47756 | Y59 | Sugiyama | CAPZB | LLSSVDQPLKIARDKVVGKDyLLCDyNRDGDSyRsPWSNKy |
| P48643 | Y274 | Sugiyama | CCT5 CCTE KIAA0098 | PFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQQIKE |
| P48741 | Y43 | Sugiyama | HSPA7 HSP70B | FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL |
| P49207 | Y32 | Sugiyama | RPL34 | sYNtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGR |
| P49207 | Y34 | Sugiyama | RPL34 | NtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGRLR |
| P49321 | Y540 | Sugiyama | NASP | DMLDLAKIIFKRQETKEAQLyAAQAHLKLGEVSVESENYVQ |
| P49327 | Y2034 | Sugiyama | FASN FAS | DYFVVFSSVSCGRGNAGQsNyGFANsAMERICEKRRHEGLP |
| P49327 | Y2462 | Sugiyama | FASN FAS | NVMLLRAKtGGAyGEDLGADyNLsQVCDGKVsVHVIEGDHR |
| P49327 | Y45 | Sugiyama | FASN FAS | NLIGGVDMVTDDDRRWKAGLyGLPRRsGKLKDLSRFDAsFF |
| P49419 | Y88 | Sugiyama | ALDH7A1 ATQ1 | tyCPANNEPIARVRQAsVADyEEtVKKAREAWKIWADIPAP |
| P49588 | Y690 | Sugiyama | AARS1 AARS | DCPLAAAKAIQGLRAVFDEtyPDPVRVVSIGVPVSELLDDP |
| P49736 | Y137 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | MRQRDREAGRGLGRMRRGLLyDsDEEDEERPARKRRQVERA |
| P49736 | Y234 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | VFKERIsDMCKENREsLVVNyEDLAAREHVLAYFLPEAPAE |
| P49840 | Y279 | Sugiyama | GSK3A | LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS |
| P49841 | Y216 | Sugiyama | GSK3B | LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS |
| P50395 | Y404 | Sugiyama | GDI2 RABGDIB | SDLLVPKDLGtEsQIFIsRTyDAttHFEttCDDIKNIYKRM |
| P50897 | Y264 | Sugiyama | PPT1 CLN1 PPT | FGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLVFLA |
| P50990 | Y30 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | GFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTTRTAYGPN |
| P50990 | Y426 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | KRLVPGGGAtEIELAKQItsyGETCPGLEQyAIKKFAEAFE |
| P50990 | Y436 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | EIELAKQItsyGETCPGLEQyAIKKFAEAFEAIPRALAENS |
| P50991 | Y269 | Sugiyama | CCT4 CCTD SRB | IQFCLSAPKTDMDNQIVVSDyAQMDRVLREERAYILNLVKQ |
| P50995 | Y482 | Sugiyama | ANXA11 ANX11 | sEtDLLDIRSEYKRMYGKsLyHDISGDtsGDyRKILLKICG |
| P51116 | Y614 | Sugiyama | FXR2 FMR1L2 | RGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLERTKPs |
| P51965 | Y77 | Sugiyama | UBE2E1 UBCH6 | ADITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF |
| P52272 | Y681 | Sugiyama | HNRNPM HNRPM NAGR1 | PFDFTWKMLKDKFNECGHVLyADIKMENGKSKGCGVVKFEs |
| P52565 | Y144 | Sugiyama | ARHGDIA GDIA1 | SGMKYIQHTyRKGVKIDKtDyMVGsYGPRAEEyEFLtPVEE |
| P52565 | Y156 | Sugiyama | ARHGDIA GDIA1 | GVKIDKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYs |
| P52597 | Y194 | Sugiyama | HNRNPF HNRPF | ERIGHRYIEVFKssQEEVRsysDPPLKFMsVQRPGPYDRPG |
| P52597 | Y82 | Sugiyama | HNRNPF HNRPF | GsEDDVKMALKKDRESMGHRyIEVFKSHRTEMDWVLKHsGP |
| P52788 | Y336 | Sugiyama | SMS | GNCVNLTEALSLYEEQLGRLyCPVEFSKEIVCVPSYLELWV |
| P53597 | Y78 | Sugiyama | SUCLG1 | IICQGFTGKQGtFHSQQALEyGtKLVGGTTPGKGGQTHLGL |
| P53675 | Y921 | Sugiyama | CLTCL1 CLH22 CLTCL CLTD | DSSVVGRYCEKRDPHLACVAyERGQCDLELIKVCNENSLFK |
| P54105 | Y214 | Sugiyama | CLNS1A CLCI ICLN | QsVssQYNMAGVRtEDsIRDyEDGMEVDttPtVAGQFEDAD |
| P54577 | T290 | Sugiyama | YARS1 YARS | PLKSEFVILRDEKWGGNKTytAyVDLEKDFAAEVVHPGDLK |
| P54577 | Y289 | Sugiyama | YARS1 YARS | FPLKSEFVILRDEKWGGNKTytAyVDLEKDFAAEVVHPGDL |
| P54577 | Y292 | Sugiyama | YARS1 YARS | KSEFVILRDEKWGGNKTytAyVDLEKDFAAEVVHPGDLKNS |
| P54577 | Y388 | Sugiyama | YARS1 YARS | LDIRVGKIITVEKHPDADsLyVEKIDVGEAEPRTVVSGLVQ |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P54753 | Y812 | Sugiyama | EPHB3 ETK2 HEK2 TYRO6 | ytssLGGKIPIRWTAPEAIAyRKFTSASDVWSYGIVMWEVM |
| P54756 | T834 | Sugiyama | EPHA5 BSK EHK1 HEK7 TYRO4 | CKVSDFGLsRVLEDDPEAAyttRGGKIPIRWTAPEAIAFRK |
| P54756 | T835 | Sugiyama | EPHA5 BSK EHK1 HEK7 TYRO4 | KVSDFGLsRVLEDDPEAAyttRGGKIPIRWTAPEAIAFRKF |
| P54756 | Y833 | Sugiyama | EPHA5 BSK EHK1 HEK7 TYRO4 | VCKVSDFGLsRVLEDDPEAAyttRGGKIPIRWTAPEAIAFR |
| P54762 | Y798 | Sugiyama | EPHB1 ELK EPHT2 HEK6 NET | yTSSLGGKIPVRWTAPEAIAyRKFTSASDVWSYGIVMWEVM |
| P54764 | T780 | Sugiyama | EPHA4 HEK8 SEK TYRO1 | CKVSDFGMSRVLEDDPEAAyttRGGKIPIRWTAPEAIAyRK |
| P54764 | T781 | Sugiyama | EPHA4 HEK8 SEK TYRO1 | KVSDFGMSRVLEDDPEAAyttRGGKIPIRWTAPEAIAyRKF |
| P54764 | Y596 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | EPHA4 HEK8 SEK TYRO1 | YSKAKQEADEEKHLNQGVRtyVDPFtyEDPNQAVREFAKEI |
| P54764 | Y602 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | EPHA4 HEK8 SEK TYRO1 | EADEEKHLNQGVRtyVDPFtyEDPNQAVREFAKEIDASCIK |
| P54764 | Y736 | Sugiyama | EPHA4 HEK8 SEK TYRO1 | GRFTVIQLVGMLRGIGSGMKyLSDMSyVHRDLAARNILVNS |
| P54764 | Y742 | Sugiyama | EPHA4 HEK8 SEK TYRO1 | QLVGMLRGIGSGMKyLSDMSyVHRDLAARNILVNSNLVCKV |
| P54764 | Y779 | PSP|Sugiyama | EPHA4 HEK8 SEK TYRO1 | VCKVSDFGMSRVLEDDPEAAyttRGGKIPIRWTAPEAIAyR |
| P54764 | Y798 | Sugiyama | EPHA4 HEK8 SEK TYRO1 | AyttRGGKIPIRWTAPEAIAyRKFTSASDVWSYGIVMWEVM |
| P55209 | Y96 | Sugiyama | NAP1L1 NRP | RRVNALKNLQVKCAQIEAKFyEEVHDLERKyAVLyQPLFDK |
| P55786 | Y173 | Sugiyama | NPEPPS PSA | NDKMKGFYRSKYTTPSGEVRyAAVTQFEATDARRAFPCWDE |
| P55795 | Y266 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst |
| P55884 | Y768 | Sugiyama | EIF3B EIF3S9 | ERRRTMMEDFRKYRKMAQELyMEQKNERLELRGGVDTDELD |
| P56945 | T385 | Sugiyama | BCAR1 CAS CASS1 CRKAS | PPPAPDLyDVPPGLRRPGPGtLyDVPRERVLPPEVADGGVV |
| P56945 | Y387 | Sugiyama | BCAR1 CAS CASS1 CRKAS | PAPDLyDVPPGLRRPGPGtLyDVPRERVLPPEVADGGVVDs |
| P57053 | Y38 | Sugiyama | H2BC12L H2BFS H2BS1 | AVTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssK |
| P57053 | Y41 | Sugiyama | H2BC12L H2BFS H2BS1 | KAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| P57053 | Y43 | Sugiyama | H2BC12L H2BFS H2BS1 | QKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| P58876 | Y38 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK |
| P58876 | Y41 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| P58876 | Y43 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| P60174 | Y209 | Sugiyama | TPI1 TPI | LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60660 | Y29 | Sugiyama | MYL6 | TAEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVL |
| P60660 | Y86 | Sugiyama | MYL6 | DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG |
| P60660 | Y89 | Sugiyama | MYL6 | HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI |
| P60709 | Y198 | Sugiyama | ACTB | LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60709 | Y362 | Sugiyama | ACTB | GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P60981 | Y82 | Sugiyama | DSTN ACTDP DSN | VTITDPFKHFVGMLPEKDCRyALyDAsFETKESRKEELMFF |
| P60981 | Y85 | Sugiyama | DSTN ACTDP DSN | TDPFKHFVGMLPEKDCRyALyDAsFETKESRKEELMFFLWA |
| P61081 | Y172 | Sugiyama | UBE2M UBC12 | VLQNNRRLFEQNVQRSMRGGyIGstyFERCLK_________ |
| P61081 | Y177 | Sugiyama | UBE2M UBC12 | RRLFEQNVQRSMRGGyIGstyFERCLK______________ |
| P61158 | Y231 | Sugiyama | ACTR3 ARP3 | REVGIPPEQSLETAKAVKERysyVCPDLVKEFNKYDTDGSK |
| P61158 | Y233 | Sugiyama | ACTR3 ARP3 | VGIPPEQSLETAKAVKERysyVCPDLVKEFNKYDTDGSKWI |
| P61163 | Y33 | Sugiyama | ACTR1A CTRN1 | VIDNGSGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALE |
| P61163 | Y38 | Sugiyama | ACTR1A CTRN1 | SGVIKAGFAGDQIPKyCFPNyVGRPKHVRVMAGALEGDIFI |
| P61221 | S591 | Sugiyama | ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 | NNYRPRINKLNsIKDVEQKKsGNyFFLDD____________ |
| P61221 | Y594 | Sugiyama | ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 | RPRINKLNsIKDVEQKKsGNyFFLDD_______________ |
| P61313 | Y62 | Sugiyama | RPL15 EC45 TCBAP0781 | PTRPDKARRLGYKAKQGyVIyRIRVRRGGRKRPVPKGAtyG |
| P61353 | Y77 | Sugiyama | RPL27 | MGKKKIAKRSKIKSFVKVyNyNHLMPtRysVDIPLDKtVVN |
| P61353 | Y85 | Sugiyama | RPL27 | RSKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPA |
| P61978 | Y323 | Sugiyama | HNRNPK HNRPK | RARNLPLPPPPPPRGGDLMAyDRRGRPGDRYDGMVGFSADE |
| P61981 | Y20 | Sugiyama | YWHAG | _MVDREQLVQKARLAEQAERyDDMAAAMKNVtELNEPLsNE |
| P61981 | Y49 | Sugiyama | YWHAG | NVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK |
| P62191 | Y184 | Sugiyama | PSMC1 | MDDTDPLVTVMKVEKAPQETyADIGGLDNQIQEIKESVELP |
| P62195 | Y148 | Sugiyama | PSMC5 SUG1 | PNKVDPLVSLMMVEKVPDSTyEMIGGLDKQIKEIKEVIELP |
| P62195 | Y189 | Sugiyama | PSMC5 SUG1 | VKHPELFEALGIAQPKGVLLyGPPGtGKTLLARAVAHHTDC |
| P62241 | Y113 | Sugiyama | RPS8 OK/SW-cl.83 | TKTLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEE |
| P62241 | Y117 | Sugiyama | RPS8 OK/SW-cl.83 | VKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEEIL |
| P62249 | Y115 | Sugiyama | RPS16 | YYQKYVDEASKKEIKDILIQyDRtLLVADPRRCESKKFGGP |
| P62258 | Y152 | Sugiyama | YWHAE | LAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLG |
| P62258 | Y49 | Sugiyama | YWHAE | KVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssIEQK |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62269 | Y95 | Sugiyama | RPS18 D6S218E | RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK |
| P62273 | Y7 | Sugiyama | RPS29 | ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR |
| P62280 | T54 | Sugiyama | RPS11 | PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs |
| P62280 | Y55 | Sugiyama | RPS11 | RYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILsG |
| P62495 | Y345 | Sugiyama | ETF1 ERF1 RF1 SUP45L1 | NLDIMRYVLHCQGTEEEKILyLTPEQEKDKSHFTDKETGQE |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62750 | Y144 | Sugiyama | RPL23A | VNtLIRPDGEKKAYVRLAPDyDALDVANKIGII________ |
| P62753 | Y156 | Sugiyama | RPS6 OK/SW-cl.2 | KRASRIRKLFNLsKEDDVRQyVVRKPLNKEGKKPRTKAPKI |
| P62807 | Y38 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | AVTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssK |
| P62807 | Y41 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | KAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMG |
| P62807 | Y43 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | QKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| P62826 | Y146 | Sugiyama | RAN ARA24 OK/SW-cl.81 | IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR |
| P62826 | Y147 | Sugiyama | RAN ARA24 OK/SW-cl.81 | KDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARK |
| P62906 | T9 | Sugiyama | RPL10A NEDD6 | ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL |
| P62906 | Y11 | Sugiyama | RPL10A NEDD6 | __________MSSKVsRDtLyEAVREVLHGNQRKRRKFLET |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62979 | Y148 | Sugiyama | RPS27A UBA80 UBCEP1 | AGVFMAsHFDRHyCGKCCLtyCFNKPEDK____________ |
| P63104 | Y149 | Sugiyama | YWHAZ | LAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLG |
| P63104 | Y48 | Sugiyama | YWHAZ | sVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssIEQK |
| P63220 | T52 | Sugiyama | RPS21 | IQMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRL |
| P63220 | Y53 | Sugiyama | RPS21 | QMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRLA |
| P63261 | Y198 | Sugiyama | ACTG1 ACTG | LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63261 | Y362 | Sugiyama | ACTG1 ACTG | GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68104 | Y29 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68363 | Y432 | Sugiyama | TUBA1B | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| P80303 | Y350 | Sugiyama | NUCB2 NEFA | PDsWEtLDQQQFFtEEELKEyENIIALQENELKKKADELQK |
| P98082 | Y38 | Sugiyama | DAB2 DOC2 | AAPKAPsKKEKKKGPEKTDEyLLARFKGDGVKYKAKLIGID |
| Q00526 | Y15 | Sugiyama | CDK3 CDKN3 | ______MDMFQKVEKIGEGtyGVVyKAKNRETGQLVALKKI |
| Q00534 | Y13 | Sugiyama | CDK6 CDKN6 | ________MEKDGLCRADQQyECVAEIGEGAyGKVFKARDL |
| Q00535 | Y15 | GPS6|EPSD | CDK5 CDKN5 PSSALRE | ______MQKYEKLEKIGEGtyGtVFKAKNRETHEIVALKRV |
| Q00610 | Y1487 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | LNNLFITEEDyQALRTsIDAyDNFDNIsLAQRLEKHELIEF |
| Q00610 | Y883 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | EARIHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsR |
| Q00610 | Y921 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | DsRVVGKYCEKRDPHLACVAyERGQCDLELINVCNENSLFK |
| Q00653 | Y247 | Sugiyama | NFKB2 LYT10 | NLKISRMDKTAGSVRGGDEVyLLCDKVQKDDIEVRFYEDDE |
| Q00839 | Y257 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | QKGGDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVE |
| Q00839 | Y260 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED |
| Q01082 | Y1408 | Sugiyama | SPTBN1 SPTB2 | sCADLDKWLHGLESQIQSDDyGKDLTsVNILLKKQQMLENQ |
| Q02809 | Y434 | Sugiyama | PLOD1 LLH PLOD | LWSNFWGALSADGYYARSEDyVDIVQGRRVGVWNVPYISNI |
| Q02878 | Y115 | Sugiyama | RPL6 TXREB1 | PVGGDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQ |
| Q04206 | Y100 | Sugiyama | RELA NFKB3 | DPPHRPHPHELVGKDCRDGFyEAELCPDRCIHSFQNLGIQC |
| Q04917 | Y154 | Sugiyama | YWHAH YWHA1 | LAEVASGEKKNsVVEAsEAAyKEAFEISKEQMQPTHPIRLG |
| Q04917 | Y20 | Sugiyama | YWHAH YWHA1 | _MGDREQLLQRARLAEQAERyDDMAsAMKAVtELNEPLsNE |
| Q04917 | Y49 | Sugiyama | YWHAH YWHA1 | AVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSIEQK |
| Q05048 | Y367 | Sugiyama | CSTF1 | AGLSGRQVHRTQAVFNHtEDyVLLPDERTIsLCCWDSRTAE |
| Q05639 | Y29 | Sugiyama | EEF1A2 EEF1AL STN | NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM |
| Q06830 | Y116 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK |
| Q07666 | Y145 | Sugiyama | KHDRBS1 SAM68 | LtAEIEKIQKGDSKKDDEENyLDLFsHKNMKLKERVLIPVK |
| Q08752 | Y323 | Sugiyama | PPID CYP40 CYPD | DPSNTKALYRRAQGWQGLKEyDQALADLKKAQGIAPEDKAI |
| Q08830 | Y80 | Sugiyama | FGL1 HFREP1 | VQFLDKGDENTVIDLGSKRQyADCSEIFNDGyKLSGFYKIK |
| Q08J23 | Y262 | Sugiyama | NSUN2 SAKI TRM4 | DASSIPRLQIDVDGRKEILFyDRILCDVPCSGDGtMRKNID |
| Q08J23 | Y52 | Sugiyama | NSUN2 SAKI TRM4 | AGWEGGyPEIVKENKLFEHyyQELKIVPEGEWGQFMDALRE |
| Q09028 | Y154 | Sugiyama | RBBP4 RBAP48 | PQNPCIIATKtPssDVLVFDyTKHPsKPDPsGECNPDLRLR |
| Q12874 | Y50 | Sugiyama | SF3A3 SAP61 | KSTLRDQINSDHRTRAMQDRyMEVSGNLRDLyDDKDGLRKE |
| Q12931 | Y513 | Sugiyama | TRAP1 HSP75 HSPC5 | GtRNIyyLCAPNRHLAEHsPyyEAMKKKDTEVLFCFEQFDE |
| Q12931 | Y514 | Sugiyama | TRAP1 HSP75 HSPC5 | tRNIyyLCAPNRHLAEHsPyyEAMKKKDTEVLFCFEQFDEL |
| Q12996 | Y708 | Sugiyama | CSTF3 | NEDsDEDEEKGAVVPPVHDIyRARQQKRIR___________ |
| Q13098 | Y172 | Sugiyama | GPS1 COPS1 CSN1 | YKGNSIKESIRRGHDDLGDHyLDCGDLSNALKCYSRARDYC |
| Q13162 | Y188 | Sugiyama | PRDX4 | GLGPIRIPLLSDLTHQISKDyGVyLEDSGHTLRGLFIIDDK |
| Q13228 | Y56 | Sugiyama | SELENBP1 SBP | tGtEAPDyLATVDVDPKsPQyCQVIHRLPMPNLKDELHHSG |
| Q13242 | Y17 | Sugiyama | SRSF9 SFRS9 SRP30C | ____MsGWADERGGEGDGRIyVGNLPTDVREKDLEDLFyKY |
| Q13263 | Y133 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | TVVDCPVCKQQCFSKDIVENyFMRDsGsKAATDAQDANQCC |
| Q13283 | Y125 | Sugiyama | G3BP1 G3BP | LRRFMQtFVLAPEGsVANKFyVHNDIFRyQDEVFGGFVtEP |
| Q13310 | Y194 | Sugiyama | PABPC4 APP1 PABP4 | KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF |
| Q13435 | Y591 | Sugiyama | SF3B2 SAP145 | LHDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSD |
| Q13435 | Y592 | Sugiyama | SF3B2 SAP145 | HDAFFKWQTKPKLTIHGDLyyEGKEFETRLKEKKPGDLSDE |
| Q13547 | Y87 | Sugiyama | HDAC1 RPD3L1 | YHSDDyIKFLRSIRPDNMsEysKQMQRFNVGEDCPVFDGLF |
| Q13561 | Y207 | Sugiyama | DCTN2 DCTN50 | SKGGSGGKttGtPPDssLVtyELHsRPEQDKFSQAAKVAEL |
| Q13561 | Y313 | Sugiyama | DCTN2 DCTN50 | IAKHKASVEDADTQSKVHQLyEtIQRWsPIASTLPELVQRL |
| Q13561 | Y86 | Sugiyama | DCTN2 DCTN50 | GLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKYQRL |
| Q14152 | Y697 | Sugiyama | EIF3A EIF3S10 KIAA0139 | LEKEKKELQERLKNQEKKIDyFERAKRLEEIPLIKSAYEEQ |
| Q14194 | Y479 | Sugiyama | CRMP1 DPYSL1 ULIP3 | INVNKGMGRFIPRKAFPEHLyQRVKIRNKVFGLQGVSRGMY |
| Q14204 | Y2881 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | IDREKAMSRPILYSNWLSKDyIPVDQEELRDyVKARLKVFY |
| Q14257 | Y311 | Sugiyama | RCN2 ERC55 | NPDLFLtsEAtDyGRQLHDDyFyHDEL______________ |
| Q14257 | Y313 | Sugiyama | RCN2 ERC55 | DLFLtsEAtDyGRQLHDDyFyHDEL________________ |
| Q14568 | Y283 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI |
| Q14696 | Y58 | Sugiyama | MESD KIAA0081 MESDC2 MESDM UNQ1911/PRO4369 | PGTPDESTPPPRKKKKDIRDyNDADMARLLEQWEKDDDIEE |
| Q14697 | Y489 | Sugiyama | GANAB G2AN KIAA0088 | PHIKVDSGyRVHEELRNLGLyVKtRDGSDyEGWCWPGSAGY |
| Q15008 | Y366 | Sugiyama | PSMD6 KIAA0107 PFAAP4 | KIDKVNEIVETNRPDsKNWQyQETIKKGDLLLNRVQKLSRV |
| Q15019 | Y211 | Sugiyama | SEPTIN2 DIFF6 KIAA0158 NEDD5 SEPT2 | ERERLKKRILDEIEEHNIKIyHLPDAEsDEDEDFKEQtRLL |
| Q15056 | Y101 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | FKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRKQ |
| Q15293 | Y115 | Sugiyama | RCN1 RCN | GDGFVttEELKtWIKRVQKRyIFDNVAKVWKDYDRDKDDKI |
| Q15293 | Y147 | Sugiyama | RCN1 RCN | YDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFKKM |
| Q15293 | Y278 | Sugiyama | RCN1 RCN | LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE |
| Q15527 | Y123 | Sugiyama | SURF2 | GRRYQRALCKYEECQKQGVEyVPACLVHRRRRREDQMDGDG |
| Q15631 | Y210 | Sugiyama | TSN | sLRKRYDGLKYDVKKVEEVVyDLSIRGFNKETAAACVEK__ |
| Q15691 | Y119 | Sugiyama | MAPRE1 | GKFQDNFEFVQWFKKFFDANyDGKDyDPVAARQGQEtAVAP |
| Q15691 | Y124 | Sugiyama | MAPRE1 | NFEFVQWFKKFFDANyDGKDyDPVAARQGQEtAVAPsLVAP |
| Q15785 | Y25 | Sugiyama | TOMM34 URCC3 | FPDsVEELRAAGNESFRNGQyAEASALyGRALRVLQAQGss |
| Q16576 | Y153 | Sugiyama | RBBP7 RBAP46 | PQNPHIIATKtPssDVLVFDyTKHPAKPDPsGECNPDLRLR |
| Q16595 | Y95 | Sugiyama | FXN FRDA X25 | LMNLRKsGtLGHPGsLDEttyERLAEETLDSLAEFFEDLAD |
| Q16719 | T85 | Sugiyama | KYNU | DENAIYFLGNSLGLQPKMVKtyLEEELDKWAKIAAYGHEVG |
| Q16762 | Y165 | Sugiyama | TST | PSRPEPAVFKATLDRSLLKTyEQVLENLESKRFQLVDSRSQ |
| Q16763 | Y141 | Sugiyama | UBE2S E2EPF OK/SW-cl.73 | IHPNPESALNEEAGRLLLENyEEyAARARLLtEIHGGAGGP |
| Q16778 | Y41 | Sugiyama | H2BC21 H2BFQ HIST2H2BE | KAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKAMG |
| Q16778 | Y43 | Sugiyama | H2BC21 H2BFQ HIST2H2BE | QKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKAMGIM |
| Q4VXU2 | Y297 | Sugiyama | PABPC1L C20orf119 | KRRFEQMKQDRLRRyQGVNLyVKNLDDSIDDDKLRKEFSPY |
| Q53H82 | Y121 | Sugiyama | LACTB2 CGI-83 | IKKLPRNPQREEIIGNGEQQyVyLKDGDVIKTEGATLRVLY |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q58FF3 | Y58 | Sugiyama | HSP90B2P GRP94B GRP94P1 TRAP1 | VTFKSILFVPTFVPRGLFDEyGsKKSDYIKLYVRCVFITDD |
| Q58FF6 | S34 | Sugiyama | HSP90AB4P | IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN |
| Q58FF6 | Y32 | Sugiyama | HSP90AB4P | KEIFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDII |
| Q58FF7 | S58 | Sugiyama | HSP90AB3P HSP90BC | IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| Q58FF7 | Y492 | Sugiyama | HSP90AB3P HSP90BC | TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR |
| Q58FF7 | Y56 | Sugiyama | HSP90AB3P HSP90BC | EEIFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDII |
| Q58FF8 | S58 | Sugiyama | HSP90AB2P HSP90BB | IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| Q58FF8 | Y198 | Sugiyama | HSP90AB2P HSP90BB | DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI |
| Q58FF8 | Y260 | Sugiyama | HSP90AB2P HSP90BB | VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW |
| Q58FF8 | Y261 | Sugiyama | HSP90AB2P HSP90BB | RYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVWK |
| Q58FF8 | Y56 | Sugiyama | HSP90AB2P HSP90BB | KEIFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDII |
| Q58FG0 | Y177 | Sugiyama | HSP90AA5P HSP90AE | GQLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQ |
| Q58FG0 | Y178 | Sugiyama | HSP90AA5P HSP90AE | QLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQK |
| Q5QNW6 | Y38 | Sugiyama | H2BC18 HIST2H2BF | AVTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK |
| Q5QNW6 | Y41 | Sugiyama | H2BC18 HIST2H2BF | KVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q5QNW6 | Y43 | Sugiyama | H2BC18 HIST2H2BF | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q5VTE0 | Y29 | Sugiyama | EEF1A1P5 EEF1AL3 | NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM |
| Q5VV41 | Y216 | Sugiyama | ARHGEF16 EPHEXIN4 NBR | KKTLGRKRGHKGsFKDDPQLyQEIQERGLNtsQEsDDDILD |
| Q6DN03 | Y41 | Sugiyama | H2BC20P HIST2H2BC | KAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMG |
| Q6DN03 | Y43 | Sugiyama | H2BC20P HIST2H2BC | QKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMGIM |
| Q6DRA6 | Y41 | Sugiyama | H2BC19P HIST2H2BD | KAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMG |
| Q6DRA6 | Y43 | Sugiyama | H2BC19P HIST2H2BD | QKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKAMGIM |
| Q6PKG0 | Y633 | Sugiyama | LARP1 KIAA0731 LARP | MEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVtQtPHyM |
| Q6S8J3 | Y1062 | Sugiyama | POTEE A26C1A POTE2 | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q71U36 | Y432 | Sugiyama | TUBA1A TUBA3 | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| Q86SX6 | Y85 | Sugiyama | GLRX5 C14orf87 | PQCGFSNAVVQILRLHGVRDyAAyNVLDDPELRQGIKDYSN |
| Q86SX6 | Y88 | Sugiyama | GLRX5 C14orf87 | GFSNAVVQILRLHGVRDyAAyNVLDDPELRQGIKDYSNWPT |
| Q86UK7 | Y306 | Sugiyama | ZNF598 | QFSYAPRHSRRNEGVVGGEDyEEVDRysRQGRVARAGTRGA |
| Q86XP3 | Y573 | Sugiyama | DDX42 | VATDVAARGLDIPSIKTVINyDVARDIDTHTHRIGRTGRAG |
| Q8IUD2 | Y987 | Sugiyama | ERC1 ELKS KIAA1081 RAB6IP2 | RLVQQLKQQTQNRMKLMADNyEDDHFKssHsNQtNHKPsPD |
| Q8IWX8 | Y903 | Sugiyama | CHERP DAN26 SCAF6 | YKGVGVALDDPyENyRRNKsysFIARMKARDECK_______ |
| Q8N0Y7 | Y119 | Sugiyama | PGAM4 PGAM3 | NKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsKD |
| Q8N0Y7 | Y133 | Sugiyama | PGAM4 PGAM3 | KIWRRsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSY |
| Q8N0Y7 | Y92 | Sugiyama | PGAM4 PGAM3 | DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV |
| Q8N257 | Y41 | Sugiyama | H2BC26 H2BU1 HIST3H2BB | KAQKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKAMG |
| Q8N257 | Y43 | Sugiyama | H2BC26 H2BU1 HIST3H2BB | QKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKAMGIM |
| Q8NBS9 | Y289 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | RDGKKVDQYKGKRDLEsLREyVEsQLQRTETGATETVTPSE |
| Q8NI22 | Y135 | Sugiyama | MCFD2 SDNSF | DELINIIDGVLRDDDKNNDGyIDyAEFAKSLQ_________ |
| Q8NI22 | Y138 | Sugiyama | MCFD2 SDNSF | INIIDGVLRDDDKNNDGyIDyAEFAKSLQ____________ |
| Q92526 | Y109 | Sugiyama | CCT6B | GDGTTSNVLIIGELLKQADLyISEGLHPRIIAEGFEAAKIK |
| Q92769 | Y88 | Sugiyama | HDAC2 | YHSDEYIKFLRSIRPDNMsEysKQMQRFNVGEDCPVFDGLF |
| Q92882 | Y207 | Sugiyama | OSTF1 | sLLKKKQGTDAVRtLsNAEDyLDDEDsD_____________ |
| Q92905 | Y203 | Sugiyama | COPS5 CSN5 JAB1 | LGAFRTYPKGYKPPDEGPsEyQtIPLNKIEDFGVHCKQYYA |
| Q93079 | Y38 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK |
| Q93079 | Y41 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q93079 | Y43 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q969T4 | Y91 | Sugiyama | UBE2E3 UBCE4 UBCH9 | AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF |
| Q96A49 | Y327 | Sugiyama | SYAP1 PRO3113 | AVLEEDsADWEKELQQELQEyEVVtESEKRDENWDKEIEKM |
| Q96AE4 | Y58 | Sugiyama | FUBP1 | ARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQPDAKKV |
| Q96B18 | S424 | Sugiyama | DACT3 RRR1 | GRMAEASGRRGSPRARKAsRsQsETSLLGRASAVPSGPPKY |
| Q96D46 | S462 | Sugiyama | NMD3 CGI-07 | FLEDLEEDEAIRKNVNIyRDsAIPVEsDtDDEGAPRISLAE |
| Q96D46 | Y459 | Sugiyama | NMD3 CGI-07 | YQDFLEDLEEDEAIRKNVNIyRDsAIPVEsDtDDEGAPRIS |
| Q96G03 | Y177 | Sugiyama | PGM2 MSTP006 | CAGIMItAsHNPKQDNGYKVyWDNGAQIIsPHDKGISQAIE |
| Q96LR5 | Y85 | Sugiyama | UBE2E2 UBCH8 | AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF |
| Q96P70 | Y889 | Sugiyama | IPO9 IMP9 KIAA1192 RANBP9 HSPC273 | HGINADDKRLQDIRVKGEEIysMDEGIRTRSKSAKNPERWT |
| Q96PK6 | Y114 | Sugiyama | RBM14 SIP | ELRSLFERRGRVIECDVVKDyAFVHMEKEADAKAAIAQLNG |
| Q96QK1 | Y507 | Sugiyama | VPS35 MEM3 TCCCTA00141 | EQSLVGRFIHLLRsEDPDQQyLILNTARKHFGAGGNQRIRF |
| Q99426 | Y98 | Sugiyama | TBCB CG22 CKAP1 | PVDDGCRIHVIDHsGARLGEyEDVSRVEKytIsQEAyDQRQ |
| Q99460 | Y494 | Sugiyama | PSMD1 | RHGGSLGLGLAAMGTARQDVyDLLKTNLYQDDAVTGEAAGL |
| Q99497 | T140 | Sugiyama | PARK7 | GSKVTtHPLAKDKMMNGGHytysENRVEKDGLILtSRGPGT |
| Q99497 | Y139 | Sugiyama | PARK7 | FGSKVTtHPLAKDKMMNGGHytysENRVEKDGLILtSRGPG |
| Q99497 | Y141 | Sugiyama | PARK7 | SKVTtHPLAKDKMMNGGHytysENRVEKDGLILtSRGPGTS |
| Q99536 | Y240 | Sugiyama | VAT1 | TASASKHEALKENGVTHPIDyHttDyVDEIKKISPKGVDIV |
| Q99536 | Y245 | Sugiyama | VAT1 | KHEALKENGVTHPIDyHttDyVDEIKKISPKGVDIVMDPLG |
| Q99733 | Y85 | Sugiyama | NAP1L4 NAP2 | RRINALKQLQVRCAHIEAKFyEEVHDLERKyAALyQPLFDK |
| Q99733 | Y99 | Sugiyama | NAP1L4 NAP2 | HIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVEPtDA |
| Q99798 | Y544 | Sugiyama | ACO2 | LEAPDADELPKGEFDPGQDtyQHPPKDSsGQHVDVsPtsQR |
| Q99877 | Y38 | Sugiyama | H2BC15 H2BFD HIST1H2BN | AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK |
| Q99877 | Y41 | Sugiyama | H2BC15 H2BFD HIST1H2BN | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q99877 | Y43 | Sugiyama | H2BC15 H2BFD HIST1H2BN | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q99879 | Y38 | Sugiyama | H2BC14 H2BFE HIST1H2BM | AINKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK |
| Q99879 | Y41 | Sugiyama | H2BC14 H2BFE HIST1H2BM | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q99879 | Y43 | Sugiyama | H2BC14 H2BFE HIST1H2BM | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q99880 | Y38 | Sugiyama | H2BC13 H2BFC HIST1H2BL | AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK |
| Q99880 | Y41 | Sugiyama | H2BC13 H2BFC HIST1H2BL | KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG |
| Q99880 | Y43 | Sugiyama | H2BC13 H2BFC HIST1H2BL | QKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMGIM |
| Q9BPW8 | Y185 | Sugiyama | NIPSNAP1 | QLLLEFSFWNEPQPRMGPNIyELRTYKLKPGTMIEWGNNWA |
| Q9BQE3 | Y432 | Sugiyama | TUBA1C TUBA6 | GMEEGEFSEAREDMAALEKDyEEVGADsADGEDEGEEy___ |
| Q9BRK5 | Y342 | Sugiyama | SDF4 CAB45 PSEC0034 | MIAVADENQNHHLEPEEVLKysEFFTGSKLVDYARsVHEEF |
| Q9BS26 | T398 | Sugiyama | ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 | VASSPPESSFQKLAPsEyRytLLRDRDEL____________ |
| Q9BS26 | Y135 | Sugiyama | ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 | NGMMMKREYRGQRSVKALADyIRQQKSDPIQEIRDLAEItt |
| Q9BS26 | Y395 | Sugiyama | ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 | AQDVASSPPESSFQKLAPsEyRytLLRDRDEL_________ |
| Q9BS26 | Y397 | Sugiyama | ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 | DVASSPPESSFQKLAPsEyRytLLRDRDEL___________ |
| Q9BS40 | Y20 | Sugiyama | LXN | _MEIPPTNYPASRAALVAQNyINyQQGTPHRVFEVQKVKQA |
| Q9BS40 | Y23 | Sugiyama | LXN | IPPTNYPASRAALVAQNyINyQQGTPHRVFEVQKVKQAsME |
| Q9BU89 | Y290 | Sugiyama | DOHH HLRC1 | RESCEVALDMyEHETGRAFQyADGLEQLRGAPS________ |
| Q9BW91 | Y140 | Sugiyama | NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771 | FsPKFNEKDGHVERKSKNGLyEIENGRPRNPAGRTGLVGRG |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9BYX7 | Y362 | Sugiyama | POTEKP ACTBL3 FKSG30 | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| Q9BZZ5 | Y28 | Sugiyama | API5 MIG8 | YRNyGILADATEQVGQHKDAyQVILDGVKGGTKEKRLAAQF |
| Q9GZL7 | Y380 | Sugiyama | WDR12 | SGSLDNIVKLWDTRSCKAPLyDLAAHEDKVLSVDWTDTGLL |
| Q9H1E3 | Y146 | Sugiyama | NUCKS1 NUCKS JC7 | QEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPERKE |
| Q9H2H8 | Y141 | Sugiyama | PPIL3 | VIDGLETLDELEKLPVNEKtyRPLNDVHIKDItIHANPFAQ |
| Q9H6T3 | Y90 | Sugiyama | RPAP3 | KESSKKTREENTKNRIKsyDyEAWAKLDVDRILDELDKDDs |
| Q9H7Z7 | Y308 | Sugiyama | PTGES2 C9orf15 PGES2 | LISKRLKSRHRLQDNVREDLyEAADKWVAAVGKDRPFMGGQ |
| Q9HB71 | Y165 | Sugiyama | CACYBP S100A6BP SIP PNAS-107 | VKTDTVLILCRKKVENTRWDyLtQVEKECKEKEKPsYDtEt |
| Q9HDC5 | Y423 | Sugiyama | JPH1 JP1 | DIARAVARELsPDFyQPGPDyVKQRFQEGVDAKENPEEKVP |
| Q9NP61 | Y408 | Sugiyama | ARFGAP3 ARFGAP1 | ETVLKTTGYSDRPTARRKPDyEPVENTDEAQKKFGNVKAIs |
| Q9NQE9 | Y44 | Sugiyama | HINT3 | TTVssVGTCEAAGKsPEPKDyDstCVFCRIAGRQDPGTELL |
| Q9NQW7 | Y296 | Sugiyama | XPNPEP1 XPNPEPL XPNPEPL1 | KALCADLsPREKVWVSDKASyAVSETIPKDHRCCMPYTPIC |
| Q9NR46 | Y77 | Sugiyama | SH3GLB2 KIAA1848 PP578 | LRQTEVLLQPNPSARVEEFLyEKLDRKVPSRVTNGELLAQY |
| Q9NRX4 | Y116 | Sugiyama | PHPT1 PHP14 CGI-202 HSPC141 | AyGPAQHAISTEKIKAKyPDyEVtWANDGy___________ |
| Q9NSE4 | Y97 | Sugiyama | IARS2 | GRQQPDtELEIQQKCGFSELysWQRERKVKTEFCLHDGPPY |
| Q9NX18 | Y105 | Sugiyama | SDHAF2 C11orf79 PGL2 SDH5 | LLSLFAKEHLQHMTEKQLNLyDRLINEPSNDWDIYYWATEA |
| Q9NY33 | Y251 | Sugiyama | DPP3 | TSKLKSYEFRGsPFQVTRGDyAPILQKVVEQLEKAKAYAAN |
| Q9NYB9 | T24 | Sugiyama | ABI2 ARGBPIA | LQMLLEEEIPGGRRALFDsytNLERVADyCENNyIQSADKQ |
| Q9NYU2 | Y1516 | Sugiyama | UGGT1 GT UGCGL1 UGGT UGT1 UGTR | PMTKEPKLEAAVRIVPEWQDyDQEIKQLQIRFQKEKETGAL |
| Q9NZB2 | Y9 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | ____________MGVQGFQDyIEKHCPsAVVPVELQKLARG |
| Q9UBR2 | Y76 | Sugiyama | CTSZ | YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA |
| Q9UBS4 | Y74 | Sugiyama | DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080 | PDRNPDDPQAQEKFQDLGAAyEVLsDSEKRKQyDTyGEEGL |
| Q9UBT2 | Y159 | Sugiyama | UBA2 SAE2 UBLE1B HRIHFB2115 | SGTAGYLGQVTTIKKGVtECyECHPKPTQRTFPGCtIRNTP |
| Q9UHG3 | Y498 | Sugiyama | PCYOX1 KIAA0908 PCL1 UNQ597/PRO1183 | ALLAYHRWNGHTDMIDQDGLyEKLKTEL_____________ |
| Q9UHX1 | Y269 | Sugiyama | PUF60 FIR ROBPI SIAHBP1 | FGKIKSCTLARDPTTGKHKGyGFIEyEKAQSSQDAVSSMNL |
| Q9UHX1 | Y274 | Sugiyama | PUF60 FIR ROBPI SIAHBP1 | SCTLARDPTTGKHKGyGFIEyEKAQSSQDAVSSMNLFDLGG |
| Q9UI15 | Y192 | Sugiyama | TAGLN3 NP25 | NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________ |
| Q9UKS6 | Y372 | Sugiyama | PACSIN3 | EWsDEEsPRKAATGVRVRALyDyAGQEADELsFRAGEELLK |
| Q9UKS6 | Y374 | Sugiyama | PACSIN3 | sDEEsPRKAATGVRVRALyDyAGQEADELsFRAGEELLKMS |
| Q9UKV3 | Y1086 | Sugiyama | ACIN1 ACINUS KIAA0670 | RTALHGVKWPQSNPKFLCADyAEQDELDyHRGLLVDRPsEt |
| Q9UKY7 | Y244 | Sugiyama | CDV3 H41 | NRGRDEVSKNQALKLQLDNQyAVLENQKSSHSQYN______ |
| Q9ULF5 | Y596 | Sugiyama | SLC39A10 KIAA1265 ZIP10 | RLNEtELtDLEGQQEsPPKNyLCIEEEKIIDHsHsDGLHtI |
| Q9UMS0 | Y194 | Sugiyama | NFU1 HIRIP5 CGI-33 | KELLDTRIRPTVQEDGGDVIyKGFEDGIVQLKLQGSCTSCP |
| Q9UMS4 | Y108 | Sugiyama | PRPF19 NMP200 PRP19 SNEV | HSFTLRQQLQTTRQELSHALyQHDAACRVIARLTKEVTAAR |
| Q9UN86 | Y125 | Sugiyama | G3BP2 KIAA0660 | ERKFMQTFVLAPEGSVPNKFyVHNDMFRYEDEVFGDsEPEL |
| Q9UNF1 | Y313 | Sugiyama | MAGED2 BCG1 | KDQTKIPIKRSDMLKDIIKEyTDVyPEIIERAGYSLEKVFG |
| Q9UNH7 | Y220 | Sugiyama | SNX6 | VSGVKDVDDFFEHERTFLLEyHNRVKDASAKSDRMTRSHKS |
| Q9UQ80 | Y98 | Sugiyama | PA2G4 EBP1 | TSISVNNCVCHFsPLKSDQDyILKEGDLVKIDLGVHVDGFI |
| Q9Y230 | Y430 | Sugiyama | RUVBL2 INO80J TIP48 TIP49B CGI-46 | SLVCRKRKGtEVQVDDIKRVysLFLDEsRSTQYMKEyQDAF |
| Q9Y262 | Y409 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | QLREKYGDKMLRMQKGDPQVyEELFsysCPKFLSPVVPNYD |
| Q9Y262 | Y415 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | GDKMLRMQKGDPQVyEELFsysCPKFLSPVVPNYDNVHPNY |
| Q9Y281 | Y82 | Sugiyama | CFL2 | DTVEDPYtsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFI |
| Q9Y281 | Y89 | Sugiyama | CFL2 | tsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPESA |
| Q9Y2B0 | Y92 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | ARsEAHLtELLEEICDRMKEyGEQIDPstHRKNYVRVVGRN |
| Q9Y3D8 | Y31 | Sugiyama | AK6 CINAP AD-004 CGI-137 | TPGVGKTTLGKELASKSGLKyINVGDLAREEQLYDGYDEEY |
| Q9Y3F4 | T105 | Sugiyama | STRAP MAWD UNRIP | VWDAVSGDELMTLAHKHIVKtVDFtQDSNyLLtGGQDKLLR |
| Q9Y3U8 | Y53 | Sugiyama | RPL36 | LTKHTKFVRDMIREVCGFAPyERRAMELLKVSKDKRALKFI |
| Q9Y450 | Y56 | Sugiyama | HBS1L HBS1 KIAA1038 | TAAQFIYSRRDKPsVEPVEEyDyEDLKEssNsVsNHQLSGF |
| Q9Y450 | Y58 | Sugiyama | HBS1L HBS1 KIAA1038 | AQFIYSRRDKPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQ |
| Q9Y490 | Y1893 | Sugiyama | TLN1 KIAA1027 TLN | TKsNtsPEELGPLANQLTsDyGRLAsEAKPAAVAAENEEIG |
| Q9Y4L1 | Y116 | Sugiyama | HYOU1 GRP170 HSPH4 ORP150 | TLRYFQHLLGKQADNPHVALyQARFPEHELTFDPQRQTVHF |
| Q9Y4X5 | Y554 | Sugiyama | ARIH1 ARI MOP6 UBCH7BP HUSSY-27 | SRRRVLLQHVHEGYEKDLWEyIED_________________ |
| Q9Y5S9 | S56 | Sugiyama | RBM8A RBM8 HSPC114 MDS014 | KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF |
| Q9Y5S9 | Y96 | Sugiyama | RBM8A RBM8 HSPC114 MDS014 | FVTGVHEEATEEDIHDKFAEyGEIKNIHLNLDRRTGYLKGy |
| Q9Y5V3 | Y505 | Sugiyama | MAGED1 NRAGE PP2250 PRO2292 | KDYTKVPIKRSEMLRDIIREyTDVyPEIIERACFVLEKKFG |
| Q9Y639 | Y216 | Sugiyama | NPTN SDFR1 SDR1 | KNASNMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKA |
| Q9Y639 | Y220 | Sugiyama | NPTN SDFR1 SDR1 | NMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKAAPDI |
| Q9Y696 | Y244 | Sugiyama | CLIC4 | AysRDEFtNtCPsDKEVEIAysDVAKRLTK___________ |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 1.244208e-08 | 7.905 | 1 | 1 |
| EPH-Ephrin signaling | R-HSA-2682334 | 2.053918e-08 | 7.687 | 1 | 1 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 1.939002e-06 | 5.712 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 1.839000e-06 | 5.735 | 1 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.027636e-05 | 4.693 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 4.793984e-05 | 4.319 | 1 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 9.253408e-05 | 4.034 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.062093e-04 | 3.974 | 1 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.265109e-04 | 3.898 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.265109e-04 | 3.898 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 1.487374e-04 | 3.828 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.611622e-04 | 3.793 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 1.764822e-04 | 3.753 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.962081e-04 | 3.707 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 2.520485e-04 | 3.599 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 3.292479e-04 | 3.482 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 3.817044e-04 | 3.418 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 4.930744e-04 | 3.307 | 1 | 1 |
| Potential therapeutics for SARS | R-HSA-9679191 | 5.377481e-04 | 3.269 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 6.135798e-04 | 3.212 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 6.810543e-04 | 3.167 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 7.536206e-04 | 3.123 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 8.072676e-04 | 3.093 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 9.026565e-04 | 3.044 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 1.003957e-03 | 2.998 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.697794e-04 | 3.013 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 1.018655e-03 | 2.992 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 1.219268e-03 | 2.914 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 1.239766e-03 | 2.907 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 1.307644e-03 | 2.884 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 1.307644e-03 | 2.884 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.629906e-03 | 2.788 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 2.002379e-03 | 2.698 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 2.255275e-03 | 2.647 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.420981e-03 | 2.616 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 2.338986e-03 | 2.631 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.430131e-03 | 2.614 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 2.594875e-03 | 2.586 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 2.517053e-03 | 2.599 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 2.706227e-03 | 2.568 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 3.246429e-03 | 2.489 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 3.330532e-03 | 2.477 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 3.509743e-03 | 2.455 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 3.984630e-03 | 2.400 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 4.097272e-03 | 2.388 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 4.114458e-03 | 2.386 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 4.995748e-03 | 2.301 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 4.876350e-03 | 2.312 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 5.222779e-03 | 2.282 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 5.801140e-03 | 2.236 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 5.407015e-03 | 2.267 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 5.390509e-03 | 2.268 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 5.785148e-03 | 2.238 | 0 | 0 |
| Drug resistance of FLT3 mutants | R-HSA-9702506 | 1.074760e-02 | 1.969 | 0 | 0 |
| Drug resistance of KIT mutants | R-HSA-9669937 | 1.074760e-02 | 1.969 | 0 | 0 |
| Drug resistance of PDGFR mutants | R-HSA-9674415 | 1.074760e-02 | 1.969 | 0 | 0 |
| KIT mutants bind TKIs | R-HSA-9669921 | 1.074760e-02 | 1.969 | 0 | 0 |
| PDGFR mutants bind TKIs | R-HSA-9674428 | 1.074760e-02 | 1.969 | 0 | 0 |
| FLT3 mutants bind TKIs | R-HSA-9702509 | 1.074760e-02 | 1.969 | 0 | 0 |
| Sorafenib-resistant PDGFR mutants | R-HSA-9674404 | 1.074760e-02 | 1.969 | 0 | 0 |
| KW2449-resistant FLT3 mutants | R-HSA-9702569 | 1.074760e-02 | 1.969 | 0 | 0 |
| Sunitinib-resistant PDGFR mutants | R-HSA-9674401 | 1.074760e-02 | 1.969 | 0 | 0 |
| quizartinib-resistant FLT3 mutants | R-HSA-9702620 | 1.074760e-02 | 1.969 | 0 | 0 |
| midostaurin-resistant FLT3 mutants | R-HSA-9702600 | 1.074760e-02 | 1.969 | 0 | 0 |
| Imatinib-resistant PDGFR mutants | R-HSA-9674396 | 1.074760e-02 | 1.969 | 0 | 0 |
| Regorafenib-resistant PDGFR mutants | R-HSA-9674403 | 1.074760e-02 | 1.969 | 0 | 0 |
| crenolanib-resistant FLT3 mutants | R-HSA-9702581 | 1.074760e-02 | 1.969 | 0 | 0 |
| semaxanib-resistant FLT3 mutants | R-HSA-9702577 | 1.074760e-02 | 1.969 | 0 | 0 |
| tandutinib-resistant FLT3 mutants | R-HSA-9702636 | 1.074760e-02 | 1.969 | 0 | 0 |
| ponatinib-resistant FLT3 mutants | R-HSA-9702614 | 1.074760e-02 | 1.969 | 0 | 0 |
| tamatinib-resistant FLT3 mutants | R-HSA-9703009 | 1.074760e-02 | 1.969 | 0 | 0 |
| sorafenib-resistant FLT3 mutants | R-HSA-9702624 | 1.074760e-02 | 1.969 | 0 | 0 |
| Imatinib-resistant KIT mutants | R-HSA-9669917 | 1.074760e-02 | 1.969 | 0 | 0 |
| Sorafenib-resistant KIT mutants | R-HSA-9669936 | 1.074760e-02 | 1.969 | 0 | 0 |
| sunitinib-resistant FLT3 mutants | R-HSA-9702632 | 1.074760e-02 | 1.969 | 0 | 0 |
| Dasatinib-resistant KIT mutants | R-HSA-9669914 | 1.074760e-02 | 1.969 | 0 | 0 |
| Sunitinib-resistant KIT mutants | R-HSA-9669934 | 1.074760e-02 | 1.969 | 0 | 0 |
| Defective F9 secretion | R-HSA-9673218 | 1.074760e-02 | 1.969 | 0 | 0 |
| Regorafenib-resistant KIT mutants | R-HSA-9669929 | 1.074760e-02 | 1.969 | 0 | 0 |
| Nilotinib-resistant KIT mutants | R-HSA-9669926 | 1.074760e-02 | 1.969 | 0 | 0 |
| Masitinib-resistant KIT mutants | R-HSA-9669924 | 1.074760e-02 | 1.969 | 0 | 0 |
| lestaurtinib-resistant FLT3 mutants | R-HSA-9702596 | 1.074760e-02 | 1.969 | 0 | 0 |
| gilteritinib-resistant FLT3 mutants | R-HSA-9702590 | 1.074760e-02 | 1.969 | 0 | 0 |
| linifanib-resistant FLT3 mutants | R-HSA-9702998 | 1.074760e-02 | 1.969 | 0 | 0 |
| pexidartinib-resistant FLT3 mutants | R-HSA-9702605 | 1.074760e-02 | 1.969 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 8.946591e-03 | 2.048 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 6.721122e-03 | 2.173 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 9.012650e-03 | 2.045 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 8.946591e-03 | 2.048 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 7.341321e-03 | 2.134 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.153363e-02 | 1.938 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.099617e-02 | 1.959 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 6.496479e-03 | 2.187 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 1.030936e-02 | 1.987 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 1.092527e-02 | 1.962 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 8.629596e-03 | 2.064 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 1.170884e-02 | 1.931 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 1.170884e-02 | 1.931 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 6.496479e-03 | 2.187 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 7.706053e-03 | 2.113 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 7.706053e-03 | 2.113 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 8.402364e-03 | 2.076 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 7.210603e-03 | 2.142 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 8.470850e-03 | 2.072 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 6.315960e-03 | 2.200 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 1.176099e-02 | 1.930 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.202198e-02 | 1.920 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.240870e-02 | 1.906 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 1.326930e-02 | 1.877 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 1.360701e-02 | 1.866 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 1.482113e-02 | 1.829 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 1.482113e-02 | 1.829 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 1.482113e-02 | 1.829 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 1.487501e-02 | 1.828 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.566520e-02 | 1.805 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.655991e-02 | 1.781 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 1.655991e-02 | 1.781 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.655991e-02 | 1.781 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 1.655991e-02 | 1.781 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.870946e-02 | 1.728 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.870946e-02 | 1.728 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 2.015992e-02 | 1.696 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.743318e-02 | 1.759 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 2.028568e-02 | 1.693 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.129015e-02 | 1.672 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 2.138035e-02 | 1.670 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 2.207137e-02 | 1.656 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 2.207137e-02 | 1.656 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 2.337965e-02 | 1.631 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.387443e-02 | 1.622 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 2.405473e-02 | 1.619 | 0 | 0 |
| PKA activation | R-HSA-163615 | 2.610827e-02 | 1.583 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 2.610827e-02 | 1.583 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 2.610827e-02 | 1.583 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 2.610827e-02 | 1.583 | 0 | 0 |
| Signaling by juxtamembrane domain KIT mutants | R-HSA-9669935 | 3.189947e-02 | 1.496 | 0 | 0 |
| Signaling by extracellular domain mutants of KIT | R-HSA-9680187 | 3.189947e-02 | 1.496 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 3.189947e-02 | 1.496 | 0 | 0 |
| Signaling by kinase domain mutants of KIT | R-HSA-9669933 | 3.189947e-02 | 1.496 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.909576e-02 | 1.536 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 3.024873e-02 | 1.519 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 3.267287e-02 | 1.486 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 2.823027e-02 | 1.549 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 2.935464e-02 | 1.532 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 3.041902e-02 | 1.517 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.823027e-02 | 1.549 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 2.935464e-02 | 1.532 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 3.267287e-02 | 1.486 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 3.046795e-02 | 1.516 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 3.041902e-02 | 1.517 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 3.388427e-02 | 1.470 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 3.451890e-02 | 1.462 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 3.499019e-02 | 1.456 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 3.512940e-02 | 1.454 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 3.580695e-02 | 1.446 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 4.230615e-02 | 1.374 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 4.230615e-02 | 1.374 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 4.230615e-02 | 1.374 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 4.230615e-02 | 1.374 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 4.230615e-02 | 1.374 | 0 | 0 |
| Defective factor IX causes thrombophilia | R-HSA-9672383 | 4.230615e-02 | 1.374 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 4.230615e-02 | 1.374 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 4.230615e-02 | 1.374 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 4.230615e-02 | 1.374 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 4.230615e-02 | 1.374 | 0 | 0 |
| Defective cofactor function of FVIIIa variant | R-HSA-9672396 | 4.230615e-02 | 1.374 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 4.230615e-02 | 1.374 | 0 | 0 |
| Defective F9 variant does not activate FX | R-HSA-9673202 | 4.230615e-02 | 1.374 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 4.230615e-02 | 1.374 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 3.736936e-02 | 1.427 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 3.736936e-02 | 1.427 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 3.736936e-02 | 1.427 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 4.747341e-02 | 1.324 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 4.230699e-02 | 1.374 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 3.816092e-02 | 1.418 | 0 | 0 |
| tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis | R-HSA-9708296 | 4.230615e-02 | 1.374 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 4.212911e-02 | 1.375 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 4.650428e-02 | 1.333 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 3.816092e-02 | 1.418 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 4.623642e-02 | 1.335 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 4.623642e-02 | 1.335 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 3.956427e-02 | 1.403 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 4.852477e-02 | 1.314 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 4.157282e-02 | 1.381 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 4.230699e-02 | 1.374 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 4.747341e-02 | 1.324 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 4.230699e-02 | 1.374 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 4.709077e-02 | 1.327 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 3.990073e-02 | 1.399 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 4.932213e-02 | 1.307 | 0 | 0 |
| Defective gamma-carboxylation of F9 | R-HSA-9673240 | 5.260161e-02 | 1.279 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 5.260161e-02 | 1.279 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 5.488933e-02 | 1.261 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 5.500249e-02 | 1.260 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 5.562610e-02 | 1.255 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 5.562610e-02 | 1.255 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 5.562610e-02 | 1.255 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 5.562610e-02 | 1.255 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 5.562610e-02 | 1.255 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 5.844540e-02 | 1.233 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 5.844540e-02 | 1.233 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 5.844540e-02 | 1.233 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 5.844540e-02 | 1.233 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 5.956081e-02 | 1.225 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 6.278702e-02 | 1.202 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 6.278702e-02 | 1.202 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 6.278702e-02 | 1.202 | 0 | 0 |
| Extrinsic Pathway of Fibrin Clot Formation | R-HSA-140834 | 6.278702e-02 | 1.202 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 7.286355e-02 | 1.137 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 7.286355e-02 | 1.137 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 7.286355e-02 | 1.137 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 7.286355e-02 | 1.137 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 7.286355e-02 | 1.137 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 8.283235e-02 | 1.082 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 8.283235e-02 | 1.082 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 8.283235e-02 | 1.082 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 8.283235e-02 | 1.082 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 9.269458e-02 | 1.033 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 9.269458e-02 | 1.033 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 9.269458e-02 | 1.033 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 9.569268e-02 | 1.019 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 7.286355e-02 | 1.137 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 6.718923e-02 | 1.173 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 7.633785e-02 | 1.117 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 9.269458e-02 | 1.033 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 9.237526e-02 | 1.034 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 9.237526e-02 | 1.034 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.170439e-02 | 1.038 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.170439e-02 | 1.038 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.170439e-02 | 1.038 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 7.324345e-02 | 1.135 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 7.286355e-02 | 1.137 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 7.286355e-02 | 1.137 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 7.324345e-02 | 1.135 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 6.718923e-02 | 1.173 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 7.946571e-02 | 1.100 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 6.718923e-02 | 1.173 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 8.283235e-02 | 1.082 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 8.283235e-02 | 1.082 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 8.880831e-02 | 1.052 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 8.698054e-02 | 1.061 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 7.098835e-02 | 1.149 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 7.019471e-02 | 1.154 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 7.633420e-02 | 1.117 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 9.237526e-02 | 1.034 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 9.269458e-02 | 1.033 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.531560e-02 | 1.021 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 7.946571e-02 | 1.100 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 8.469798e-02 | 1.072 | 0 | 0 |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | R-HSA-159763 | 9.269458e-02 | 1.033 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 7.324345e-02 | 1.135 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 8.584616e-02 | 1.066 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 9.010541e-02 | 1.045 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 6.718923e-02 | 1.173 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 8.584616e-02 | 1.066 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 9.904385e-02 | 1.004 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 9.904385e-02 | 1.004 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 9.904385e-02 | 1.004 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 1.024277e-01 | 0.990 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 1.024514e-01 | 0.989 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 1.024514e-01 | 0.989 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 1.024514e-01 | 0.989 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 1.024514e-01 | 0.989 | 0 | 0 |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | R-HSA-159782 | 1.024514e-01 | 0.989 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.070226e-01 | 0.971 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 1.092890e-01 | 0.961 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 1.121038e-01 | 0.950 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 1.311002e-01 | 0.882 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 1.311002e-01 | 0.882 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.404463e-01 | 0.852 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 1.588397e-01 | 0.799 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 1.588397e-01 | 0.799 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 1.678891e-01 | 0.775 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 1.768417e-01 | 0.752 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 1.768417e-01 | 0.752 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 1.856985e-01 | 0.731 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 1.856985e-01 | 0.731 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 1.856985e-01 | 0.731 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 1.856985e-01 | 0.731 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 1.944606e-01 | 0.711 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 1.944606e-01 | 0.711 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 2.117045e-01 | 0.674 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 1.269403e-01 | 0.896 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.415093e-01 | 0.849 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 1.564132e-01 | 0.806 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 1.938239e-01 | 0.713 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 1.938239e-01 | 0.713 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 2.065376e-01 | 0.685 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 2.117045e-01 | 0.674 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 2.117045e-01 | 0.674 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 2.201883e-01 | 0.657 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 1.677782e-01 | 0.775 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 1.938239e-01 | 0.713 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 2.201883e-01 | 0.657 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 1.311002e-01 | 0.882 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 1.588397e-01 | 0.799 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 1.121038e-01 | 0.950 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 1.678891e-01 | 0.775 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 1.121038e-01 | 0.950 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 1.678891e-01 | 0.775 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.117045e-01 | 0.674 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 2.201883e-01 | 0.657 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 1.678891e-01 | 0.775 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 1.172679e-01 | 0.931 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 2.104696e-01 | 0.677 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.311002e-01 | 0.882 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 1.496924e-01 | 0.825 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.588397e-01 | 0.799 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 1.588397e-01 | 0.799 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 1.588397e-01 | 0.799 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 2.026139e-01 | 0.693 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 1.965586e-01 | 0.707 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 1.489229e-01 | 0.827 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 2.104696e-01 | 0.677 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 1.311002e-01 | 0.882 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.311002e-01 | 0.882 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.768417e-01 | 0.752 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.856985e-01 | 0.731 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 2.187587e-01 | 0.660 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 1.216531e-01 | 0.915 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 1.311002e-01 | 0.882 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 2.031289e-01 | 0.692 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 1.127643e-01 | 0.948 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 1.233571e-01 | 0.909 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 2.061587e-01 | 0.686 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 2.031289e-01 | 0.692 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 2.031289e-01 | 0.692 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 2.117045e-01 | 0.674 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 2.201883e-01 | 0.657 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 1.216531e-01 | 0.915 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 1.311002e-01 | 0.882 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 1.404463e-01 | 0.852 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 1.496924e-01 | 0.825 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 1.496924e-01 | 0.825 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 1.588397e-01 | 0.799 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 1.588397e-01 | 0.799 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 1.856985e-01 | 0.731 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.564132e-01 | 0.806 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.438275e-01 | 0.842 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 1.588397e-01 | 0.799 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 1.588397e-01 | 0.799 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 1.588397e-01 | 0.799 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 1.944606e-01 | 0.711 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 2.117045e-01 | 0.674 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 1.127643e-01 | 0.948 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.127643e-01 | 0.948 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.865424e-01 | 0.729 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 1.588397e-01 | 0.799 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.856985e-01 | 0.731 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.031289e-01 | 0.692 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 1.515253e-01 | 0.820 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 1.378335e-01 | 0.861 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 1.151346e-01 | 0.939 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.673340e-01 | 0.776 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 1.678891e-01 | 0.775 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 1.856985e-01 | 0.731 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 1.292782e-01 | 0.888 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.216531e-01 | 0.915 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.244965e-01 | 0.905 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.699361e-01 | 0.770 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.792799e-01 | 0.746 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 1.715980e-01 | 0.765 | 0 | 0 |
| Gamma-carboxylation of protein precursors | R-HSA-159740 | 1.496924e-01 | 0.825 | 0 | 0 |
| Gamma-carboxylation, transport, and amino-terminal cleavage of proteins | R-HSA-159854 | 1.588397e-01 | 0.799 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.588397e-01 | 0.799 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 1.404463e-01 | 0.852 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.944606e-01 | 0.711 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.216531e-01 | 0.915 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.117045e-01 | 0.674 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 2.201883e-01 | 0.657 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.201883e-01 | 0.657 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 1.378335e-01 | 0.861 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 1.639737e-01 | 0.785 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 1.588397e-01 | 0.799 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.670538e-01 | 0.777 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 1.378335e-01 | 0.861 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 1.856985e-01 | 0.731 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 1.944606e-01 | 0.711 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 1.944606e-01 | 0.711 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.365711e-01 | 0.865 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 1.305481e-01 | 0.884 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 1.292895e-01 | 0.888 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 1.404463e-01 | 0.852 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.390331e-01 | 0.857 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.390331e-01 | 0.857 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.947934e-01 | 0.710 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 1.947934e-01 | 0.710 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 1.162681e-01 | 0.935 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.198635e-01 | 0.921 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 2.223086e-01 | 0.653 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 2.269785e-01 | 0.644 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 2.285813e-01 | 0.641 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 2.285813e-01 | 0.641 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 2.285813e-01 | 0.641 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 2.285813e-01 | 0.641 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 2.285813e-01 | 0.641 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 2.300486e-01 | 0.638 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 2.302311e-01 | 0.638 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 2.368845e-01 | 0.625 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 2.368845e-01 | 0.625 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.368845e-01 | 0.625 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 2.368845e-01 | 0.625 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 2.368845e-01 | 0.625 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 2.381722e-01 | 0.623 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 2.426168e-01 | 0.615 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 2.450989e-01 | 0.611 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 2.450989e-01 | 0.611 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 2.450989e-01 | 0.611 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 2.450989e-01 | 0.611 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 2.461274e-01 | 0.609 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 2.501090e-01 | 0.602 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 2.532253e-01 | 0.596 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.532253e-01 | 0.596 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 2.532253e-01 | 0.596 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.532253e-01 | 0.596 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 2.612647e-01 | 0.583 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 2.612647e-01 | 0.583 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 2.612647e-01 | 0.583 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 2.660501e-01 | 0.575 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.660501e-01 | 0.575 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 2.692181e-01 | 0.570 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 2.692181e-01 | 0.570 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 2.692181e-01 | 0.570 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 2.692181e-01 | 0.570 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 2.740228e-01 | 0.562 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 2.761168e-01 | 0.559 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 2.770864e-01 | 0.557 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 2.770864e-01 | 0.557 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 2.770864e-01 | 0.557 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 2.770864e-01 | 0.557 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.770864e-01 | 0.557 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.770864e-01 | 0.557 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 2.780081e-01 | 0.556 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 2.790498e-01 | 0.554 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 2.790498e-01 | 0.554 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 2.819693e-01 | 0.550 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 2.848704e-01 | 0.545 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 2.848704e-01 | 0.545 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 2.848704e-01 | 0.545 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 2.848704e-01 | 0.545 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 2.848704e-01 | 0.545 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 2.848704e-01 | 0.545 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 2.925711e-01 | 0.534 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 2.925711e-01 | 0.534 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 2.925711e-01 | 0.534 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 2.979064e-01 | 0.526 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 3.001893e-01 | 0.523 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 3.001893e-01 | 0.523 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 3.001893e-01 | 0.523 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 3.001893e-01 | 0.523 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 3.001893e-01 | 0.523 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 3.018776e-01 | 0.520 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 3.024737e-01 | 0.519 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 3.027747e-01 | 0.519 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 3.077259e-01 | 0.512 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 3.083481e-01 | 0.511 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 3.151819e-01 | 0.501 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 3.151819e-01 | 0.501 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 3.216697e-01 | 0.493 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 3.216697e-01 | 0.493 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 3.225580e-01 | 0.491 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 3.295501e-01 | 0.482 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 3.298551e-01 | 0.482 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 3.298551e-01 | 0.482 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 3.316850e-01 | 0.479 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 3.370740e-01 | 0.472 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 3.370740e-01 | 0.472 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.370740e-01 | 0.472 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 3.374057e-01 | 0.472 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 3.374057e-01 | 0.472 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 3.436367e-01 | 0.464 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 3.436367e-01 | 0.464 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 3.442157e-01 | 0.463 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 3.442157e-01 | 0.463 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.442157e-01 | 0.463 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 3.442157e-01 | 0.463 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 3.442157e-01 | 0.463 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 3.442157e-01 | 0.463 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 3.452339e-01 | 0.462 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 3.495123e-01 | 0.457 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 3.495123e-01 | 0.457 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 3.512551e-01 | 0.454 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 3.512808e-01 | 0.454 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 3.582702e-01 | 0.446 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 3.582702e-01 | 0.446 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 3.593228e-01 | 0.445 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 3.651848e-01 | 0.437 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 3.651848e-01 | 0.437 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.651848e-01 | 0.437 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 3.682976e-01 | 0.434 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 3.685308e-01 | 0.434 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 3.720253e-01 | 0.429 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 3.720253e-01 | 0.429 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 3.723833e-01 | 0.429 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 3.787925e-01 | 0.422 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 3.812471e-01 | 0.419 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 3.817033e-01 | 0.418 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 3.854872e-01 | 0.414 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 3.854872e-01 | 0.414 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 3.854872e-01 | 0.414 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 3.875239e-01 | 0.412 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 3.921101e-01 | 0.407 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 3.921101e-01 | 0.407 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 3.952938e-01 | 0.403 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 3.986621e-01 | 0.399 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 3.990761e-01 | 0.399 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 4.020173e-01 | 0.396 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 4.051439e-01 | 0.392 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 4.051439e-01 | 0.392 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 4.051439e-01 | 0.392 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 4.115561e-01 | 0.386 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 4.115561e-01 | 0.386 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 4.140937e-01 | 0.383 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 4.178193e-01 | 0.379 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 4.178997e-01 | 0.379 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 4.215331e-01 | 0.375 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 4.215331e-01 | 0.375 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 4.215331e-01 | 0.375 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 4.241753e-01 | 0.372 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 4.252348e-01 | 0.371 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 4.303836e-01 | 0.366 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 4.303836e-01 | 0.366 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 4.303836e-01 | 0.366 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 4.303836e-01 | 0.366 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 4.303836e-01 | 0.366 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 4.307018e-01 | 0.366 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 4.326013e-01 | 0.364 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 4.326013e-01 | 0.364 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 4.355838e-01 | 0.361 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 4.365253e-01 | 0.360 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 4.399176e-01 | 0.357 | 0 | 0 |
| M Phase | R-HSA-68886 | 4.409532e-01 | 0.356 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 4.426012e-01 | 0.354 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 4.426012e-01 | 0.354 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 4.426012e-01 | 0.354 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 4.426012e-01 | 0.354 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 4.426012e-01 | 0.354 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 4.426012e-01 | 0.354 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 4.426012e-01 | 0.354 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 4.426012e-01 | 0.354 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 4.426012e-01 | 0.354 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 4.486119e-01 | 0.348 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 4.486119e-01 | 0.348 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 4.543949e-01 | 0.343 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 4.543949e-01 | 0.343 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 4.545582e-01 | 0.342 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 4.588873e-01 | 0.338 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 4.604408e-01 | 0.337 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 4.662602e-01 | 0.331 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 4.720173e-01 | 0.326 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 4.720173e-01 | 0.326 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.757060e-01 | 0.323 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 4.757060e-01 | 0.323 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 4.777126e-01 | 0.321 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 4.777126e-01 | 0.321 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 4.833468e-01 | 0.316 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 4.833468e-01 | 0.316 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 4.833468e-01 | 0.316 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 4.889206e-01 | 0.311 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 4.901194e-01 | 0.310 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 4.942522e-01 | 0.306 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 4.944346e-01 | 0.306 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 4.944346e-01 | 0.306 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 4.965091e-01 | 0.304 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 4.998894e-01 | 0.301 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 4.998894e-01 | 0.301 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 4.998894e-01 | 0.301 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 4.999254e-01 | 0.301 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 4.999254e-01 | 0.301 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 5.033269e-01 | 0.298 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 5.052857e-01 | 0.296 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 5.052857e-01 | 0.296 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 5.053803e-01 | 0.296 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 5.159053e-01 | 0.287 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 5.159053e-01 | 0.287 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 5.186658e-01 | 0.285 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 5.211298e-01 | 0.283 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 5.211298e-01 | 0.283 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 5.211298e-01 | 0.283 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 5.211298e-01 | 0.283 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 5.211298e-01 | 0.283 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 5.211298e-01 | 0.283 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 5.262982e-01 | 0.279 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 5.262982e-01 | 0.279 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 5.299985e-01 | 0.276 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 5.314112e-01 | 0.275 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 5.314112e-01 | 0.275 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 5.314112e-01 | 0.275 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 5.332640e-01 | 0.273 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 5.364692e-01 | 0.270 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 5.364692e-01 | 0.270 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 5.365140e-01 | 0.270 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 5.365140e-01 | 0.270 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 5.397485e-01 | 0.268 | 1 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 5.414730e-01 | 0.266 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 5.414730e-01 | 0.266 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 5.414730e-01 | 0.266 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 5.414730e-01 | 0.266 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 5.464231e-01 | 0.262 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 5.464231e-01 | 0.262 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 5.513201e-01 | 0.259 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 5.561644e-01 | 0.255 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 5.609568e-01 | 0.251 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 5.609568e-01 | 0.251 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 5.609568e-01 | 0.251 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 5.609568e-01 | 0.251 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 5.703877e-01 | 0.244 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.703877e-01 | 0.244 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 5.703877e-01 | 0.244 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 5.722868e-01 | 0.242 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 5.750274e-01 | 0.240 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 5.750274e-01 | 0.240 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 5.796172e-01 | 0.237 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 5.796172e-01 | 0.237 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 5.796172e-01 | 0.237 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 5.796427e-01 | 0.237 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 5.841578e-01 | 0.233 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 5.841578e-01 | 0.233 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 5.841578e-01 | 0.233 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 5.841578e-01 | 0.233 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 5.841578e-01 | 0.233 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 5.886495e-01 | 0.230 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 5.886495e-01 | 0.230 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 5.894852e-01 | 0.230 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 5.909448e-01 | 0.228 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 5.930931e-01 | 0.227 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 5.930931e-01 | 0.227 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 5.930931e-01 | 0.227 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 5.974889e-01 | 0.224 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 5.974889e-01 | 0.224 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 6.061394e-01 | 0.217 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 6.061394e-01 | 0.217 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 6.061394e-01 | 0.217 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 6.098051e-01 | 0.215 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 6.103950e-01 | 0.214 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 6.110947e-01 | 0.214 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 6.146050e-01 | 0.211 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 6.146050e-01 | 0.211 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 6.155007e-01 | 0.211 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 6.228896e-01 | 0.206 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 6.228896e-01 | 0.206 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 6.269653e-01 | 0.203 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 6.309972e-01 | 0.200 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 6.309972e-01 | 0.200 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 6.349858e-01 | 0.197 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 6.389315e-01 | 0.195 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 6.389315e-01 | 0.195 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 6.389315e-01 | 0.195 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 6.428348e-01 | 0.192 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 6.430290e-01 | 0.192 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 6.466961e-01 | 0.189 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 6.505159e-01 | 0.187 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 6.505159e-01 | 0.187 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 6.542947e-01 | 0.184 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 6.580328e-01 | 0.182 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 6.580328e-01 | 0.182 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 6.617307e-01 | 0.179 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 6.617307e-01 | 0.179 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 6.639216e-01 | 0.178 | 0 | 0 |
| Protein folding | R-HSA-391251 | 6.690078e-01 | 0.175 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 6.690078e-01 | 0.175 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 6.698991e-01 | 0.174 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 6.725877e-01 | 0.172 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 6.725877e-01 | 0.172 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 6.761291e-01 | 0.170 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 6.796325e-01 | 0.168 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 6.796325e-01 | 0.168 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 6.862452e-01 | 0.164 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 6.865265e-01 | 0.163 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 6.865265e-01 | 0.163 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 6.899180e-01 | 0.161 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 6.910389e-01 | 0.160 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 6.932730e-01 | 0.159 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 6.932730e-01 | 0.159 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 6.932730e-01 | 0.159 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 6.965919e-01 | 0.157 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 6.965919e-01 | 0.157 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 6.998752e-01 | 0.155 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 7.027609e-01 | 0.153 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 7.031230e-01 | 0.153 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 7.063360e-01 | 0.151 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 7.063360e-01 | 0.151 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 7.113011e-01 | 0.148 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 7.157688e-01 | 0.145 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 7.157688e-01 | 0.145 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 7.163400e-01 | 0.145 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 7.187228e-01 | 0.143 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 7.188457e-01 | 0.143 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 7.218894e-01 | 0.142 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 7.249004e-01 | 0.140 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 7.251024e-01 | 0.140 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 7.272571e-01 | 0.138 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 7.278790e-01 | 0.138 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.278790e-01 | 0.138 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 7.293977e-01 | 0.137 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 7.308254e-01 | 0.136 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 7.308254e-01 | 0.136 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 7.308254e-01 | 0.136 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 7.331218e-01 | 0.135 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 7.337402e-01 | 0.134 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 7.337402e-01 | 0.134 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 7.422975e-01 | 0.129 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.422975e-01 | 0.129 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 7.505814e-01 | 0.125 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 7.532834e-01 | 0.123 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 7.688951e-01 | 0.114 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 7.730070e-01 | 0.112 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 7.738775e-01 | 0.111 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 7.738775e-01 | 0.111 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 7.881930e-01 | 0.103 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 7.964759e-01 | 0.099 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 7.972323e-01 | 0.098 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 7.994315e-01 | 0.097 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 8.007750e-01 | 0.096 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 8.100770e-01 | 0.091 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 8.100770e-01 | 0.091 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 8.143319e-01 | 0.089 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 8.195935e-01 | 0.086 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 8.233317e-01 | 0.084 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 8.278426e-01 | 0.082 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 8.333892e-01 | 0.079 | 0 | 0 |
| S Phase | R-HSA-69242 | 8.351983e-01 | 0.078 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 8.387581e-01 | 0.076 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 8.395346e-01 | 0.076 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 8.405093e-01 | 0.075 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 8.436604e-01 | 0.074 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 8.439550e-01 | 0.074 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 8.439550e-01 | 0.074 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 8.456500e-01 | 0.073 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.473267e-01 | 0.072 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.506260e-01 | 0.070 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 8.538544e-01 | 0.069 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 8.554425e-01 | 0.068 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 8.562520e-01 | 0.067 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 8.616250e-01 | 0.065 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.660887e-01 | 0.062 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 8.745912e-01 | 0.058 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 8.924001e-01 | 0.049 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 8.958760e-01 | 0.048 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 8.970097e-01 | 0.047 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 8.985538e-01 | 0.046 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 8.992403e-01 | 0.046 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 9.035584e-01 | 0.044 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 9.076925e-01 | 0.042 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.106770e-01 | 0.041 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 9.328347e-01 | 0.030 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 9.334330e-01 | 0.030 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 9.341516e-01 | 0.030 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 9.391532e-01 | 0.027 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.419802e-01 | 0.026 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.454828e-01 | 0.024 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 9.472507e-01 | 0.024 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 9.479991e-01 | 0.023 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.538184e-01 | 0.021 | 0 | 0 |
| Translation | R-HSA-72766 | 9.566977e-01 | 0.019 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.659655e-01 | 0.015 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 9.756004e-01 | 0.011 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.776530e-01 | 0.010 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 9.822896e-01 | 0.008 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 9.848309e-01 | 0.007 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.853871e-01 | 0.006 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.893591e-01 | 0.005 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.920049e-01 | 0.003 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 9.987927e-01 | 0.001 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 9.998037e-01 | 0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 9.999888e-01 | 0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | 0.000 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 1.000000e+00 | 0.000 | 1 | 0 |
| Somitogenesis | R-HSA-9824272 | 1.000000e+00 | 0.000 | 1 | 1 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.110223e-16 | 15.955 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 3.330669e-16 | 15.477 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 1.421085e-14 | 13.847 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 7.061018e-14 | 13.151 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 7.793766e-14 | 13.108 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 2.161604e-13 | 12.665 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 2.161604e-13 | 12.665 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.103073e-13 | 12.508 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 3.523848e-13 | 12.453 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 4.051204e-13 | 12.392 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 5.184742e-13 | 12.285 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 5.021539e-13 | 12.299 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 5.478951e-13 | 12.261 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 7.633894e-13 | 12.117 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 8.932854e-13 | 12.049 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 8.932854e-13 | 12.049 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 9.726664e-13 | 12.012 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 1.281975e-12 | 11.892 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 1.409539e-12 | 11.851 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 1.868838e-12 | 11.728 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 2.180145e-12 | 11.662 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 2.180145e-12 | 11.662 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 3.611778e-12 | 11.442 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 4.068523e-12 | 11.391 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 4.606759e-12 | 11.337 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 4.606759e-12 | 11.337 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 5.155654e-12 | 11.288 | 0 | 0 |
| Depurination | R-HSA-73927 | 5.842549e-12 | 11.233 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 6.161183e-12 | 11.210 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 7.622347e-12 | 11.118 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 7.545742e-12 | 11.122 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 7.545742e-12 | 11.122 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 7.622347e-12 | 11.118 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 8.212653e-12 | 11.086 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 9.247936e-12 | 11.034 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 9.247936e-12 | 11.034 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 8.909429e-12 | 11.050 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 1.154699e-11 | 10.938 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 1.154699e-11 | 10.938 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 1.488498e-11 | 10.827 | 1 | 1 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.851341e-11 | 10.733 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.774936e-11 | 10.751 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.774936e-11 | 10.751 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.885958e-11 | 10.724 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 2.185918e-11 | 10.660 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 2.512246e-11 | 10.600 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 2.931466e-11 | 10.533 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 3.274125e-11 | 10.485 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 3.274125e-11 | 10.485 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 3.323064e-11 | 10.478 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 3.610001e-11 | 10.442 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 3.610001e-11 | 10.442 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 3.992984e-11 | 10.399 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 5.619472e-11 | 10.250 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 5.619472e-11 | 10.250 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 5.830114e-11 | 10.234 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 6.497491e-11 | 10.187 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 8.813339e-11 | 10.055 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.005843e-10 | 9.997 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 1.081091e-10 | 9.966 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 1.198592e-10 | 9.921 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.377700e-10 | 9.861 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 1.686615e-10 | 9.773 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 3.773817e-10 | 9.423 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 5.370749e-10 | 9.270 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 6.082871e-10 | 9.216 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.053078e-09 | 8.978 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 1.209027e-09 | 8.918 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 2.344267e-09 | 8.630 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.765916e-09 | 8.558 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 2.666145e-09 | 8.574 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.765916e-09 | 8.558 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 2.765916e-09 | 8.558 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.891082e-09 | 8.539 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 3.944201e-09 | 8.404 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 4.436272e-09 | 8.353 | 1 | 0 |
| Telomere Maintenance | R-HSA-157579 | 4.565351e-09 | 8.341 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 5.083008e-09 | 8.294 | 1 | 1 |
| HATs acetylate histones | R-HSA-3214847 | 5.582001e-09 | 8.253 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 6.949783e-09 | 8.158 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 9.725306e-09 | 8.012 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.315956e-08 | 7.881 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 1.375938e-08 | 7.861 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 1.576855e-08 | 7.802 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 1.590638e-08 | 7.798 | 1 | 1 |
| Base Excision Repair | R-HSA-73884 | 2.037939e-08 | 7.691 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.254534e-08 | 7.647 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 2.443644e-08 | 7.612 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 3.032669e-08 | 7.518 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 3.452331e-08 | 7.462 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 4.032265e-08 | 7.394 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 4.047168e-08 | 7.393 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 4.734971e-08 | 7.325 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 4.738163e-08 | 7.324 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 5.131012e-08 | 7.290 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 7.638589e-08 | 7.117 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 9.902625e-08 | 7.004 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 9.902625e-08 | 7.004 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.570095e-07 | 6.804 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.933737e-07 | 6.714 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 2.067351e-07 | 6.685 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 2.069490e-07 | 6.684 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.127004e-07 | 6.672 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 2.607830e-07 | 6.584 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 3.548725e-07 | 6.450 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.952595e-07 | 6.305 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 4.356245e-07 | 6.361 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 4.708485e-07 | 6.327 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 4.675349e-07 | 6.330 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 5.053566e-07 | 6.296 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 5.478585e-07 | 6.261 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 6.100530e-07 | 6.215 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 6.203224e-07 | 6.207 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 6.203224e-07 | 6.207 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 6.232314e-07 | 6.205 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 6.232314e-07 | 6.205 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 6.232314e-07 | 6.205 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 6.339463e-07 | 6.198 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 8.439125e-07 | 6.074 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.180068e-06 | 5.928 | 1 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 1.331015e-06 | 5.876 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.619825e-06 | 5.791 | 1 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.932075e-06 | 5.714 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 2.000817e-06 | 5.699 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 2.037451e-06 | 5.691 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.790580e-06 | 5.554 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 2.928547e-06 | 5.533 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 3.042132e-06 | 5.517 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 4.397452e-06 | 5.357 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 4.420997e-06 | 5.354 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 4.469337e-06 | 5.350 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 5.087225e-06 | 5.294 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.546455e-06 | 5.256 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 6.357330e-06 | 5.197 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 6.577700e-06 | 5.182 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 8.440017e-06 | 5.074 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 8.952120e-06 | 5.048 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 1.239261e-05 | 4.907 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.442371e-05 | 4.841 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.540187e-05 | 4.812 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.560584e-05 | 4.807 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.734839e-05 | 4.761 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.734839e-05 | 4.761 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.734839e-05 | 4.761 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.793815e-05 | 4.746 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.254174e-05 | 4.647 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 2.343253e-05 | 4.630 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 2.666895e-05 | 4.574 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 3.131314e-05 | 4.504 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 3.497080e-05 | 4.456 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 3.977203e-05 | 4.400 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 4.631070e-05 | 4.334 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 5.122598e-05 | 4.291 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 5.784900e-05 | 4.238 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 8.759060e-05 | 4.058 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 1.000774e-04 | 4.000 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.200727e-04 | 3.921 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 1.211310e-04 | 3.917 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.384970e-04 | 3.859 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.410279e-04 | 3.851 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.524810e-04 | 3.817 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 2.103942e-04 | 3.677 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 2.590764e-04 | 3.587 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 2.658757e-04 | 3.575 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 2.839493e-04 | 3.547 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 3.190618e-04 | 3.496 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 3.479818e-04 | 3.458 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 3.526361e-04 | 3.453 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 3.619393e-04 | 3.441 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 3.688792e-04 | 3.433 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 4.447086e-04 | 3.352 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 5.742890e-04 | 3.241 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 5.362113e-04 | 3.271 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 6.145561e-04 | 3.211 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 5.809929e-04 | 3.236 | 0 | 0 |
| Disease | R-HSA-1643685 | 4.938402e-04 | 3.306 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 6.819928e-04 | 3.166 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 6.937227e-04 | 3.159 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 9.235256e-04 | 3.035 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 9.563291e-04 | 3.019 | 0 | 0 |
| Microbial factors inhibit CASP4 activity | R-HSA-9956593 | 9.626315e-04 | 3.017 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 1.133450e-03 | 2.946 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.267596e-03 | 2.897 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.305342e-03 | 2.884 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.322267e-03 | 2.879 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 1.322267e-03 | 2.879 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.331698e-03 | 2.876 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.387304e-03 | 2.858 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.443729e-03 | 2.841 | 0 | 0 |
| Signaling by FGFR1 amplification mutants | R-HSA-1839120 | 1.480785e-03 | 2.830 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 1.529761e-03 | 2.815 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 1.613190e-03 | 2.792 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 1.756582e-03 | 2.755 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 2.100944e-03 | 2.678 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 2.116837e-03 | 2.674 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 2.323578e-03 | 2.634 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 2.364417e-03 | 2.626 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 2.535981e-03 | 2.596 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 2.688889e-03 | 2.570 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.766791e-03 | 2.558 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 2.859260e-03 | 2.544 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 3.218806e-03 | 2.492 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 3.283906e-03 | 2.484 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 3.283906e-03 | 2.484 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 3.283906e-03 | 2.484 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 3.283906e-03 | 2.484 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 3.503958e-03 | 2.455 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 3.556342e-03 | 2.449 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 3.708847e-03 | 2.431 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 4.060213e-03 | 2.391 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 4.335991e-03 | 2.363 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 4.755497e-03 | 2.323 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 6.189492e-03 | 2.208 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 5.711422e-03 | 2.243 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 5.416589e-03 | 2.266 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.788930e-03 | 2.168 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 5.711422e-03 | 2.243 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 6.277127e-03 | 2.202 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 5.487445e-03 | 2.261 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.987130e-03 | 2.223 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 6.860828e-03 | 2.164 | 0 | 0 |
| Interleukin-18 signaling | R-HSA-9012546 | 6.860828e-03 | 2.164 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 7.329418e-03 | 2.135 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 7.912681e-03 | 2.102 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 8.028473e-03 | 2.095 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 8.091899e-03 | 2.092 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 8.105939e-03 | 2.091 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 9.341370e-03 | 2.030 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 9.444524e-03 | 2.025 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 9.444524e-03 | 2.025 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 9.675603e-03 | 2.014 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 9.730001e-03 | 2.012 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 9.730001e-03 | 2.012 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 9.730001e-03 | 2.012 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 1.087439e-02 | 1.964 | 0 | 0 |
| Drug resistance of PDGFR mutants | R-HSA-9674415 | 1.105473e-02 | 1.956 | 0 | 0 |
| PDGFR mutants bind TKIs | R-HSA-9674428 | 1.105473e-02 | 1.956 | 0 | 0 |
| Imatinib-resistant PDGFR mutants | R-HSA-9674396 | 1.105473e-02 | 1.956 | 0 | 0 |
| Sorafenib-resistant PDGFR mutants | R-HSA-9674404 | 1.105473e-02 | 1.956 | 0 | 0 |
| Regorafenib-resistant PDGFR mutants | R-HSA-9674403 | 1.105473e-02 | 1.956 | 0 | 0 |
| Sunitinib-resistant PDGFR mutants | R-HSA-9674401 | 1.105473e-02 | 1.956 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.176544e-02 | 1.929 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 1.239337e-02 | 1.907 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 1.262955e-02 | 1.899 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.268306e-02 | 1.897 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.307366e-02 | 1.884 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.307366e-02 | 1.884 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.342337e-02 | 1.872 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.387585e-02 | 1.858 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 1.399935e-02 | 1.854 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 1.399935e-02 | 1.854 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 1.399935e-02 | 1.854 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 1.399935e-02 | 1.854 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 1.424504e-02 | 1.846 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 1.449408e-02 | 1.839 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 1.509469e-02 | 1.821 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.520489e-02 | 1.818 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.522240e-02 | 1.818 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 1.569024e-02 | 1.804 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 1.738052e-02 | 1.760 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 1.746399e-02 | 1.758 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 1.781249e-02 | 1.749 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 1.781249e-02 | 1.749 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.823801e-02 | 1.739 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 1.931859e-02 | 1.714 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 2.072550e-02 | 1.683 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 2.078499e-02 | 1.682 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 2.079989e-02 | 1.682 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 2.239054e-02 | 1.650 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 2.307378e-02 | 1.637 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.326240e-02 | 1.633 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 2.326240e-02 | 1.633 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 3.280092e-02 | 1.484 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 2.534775e-02 | 1.596 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 2.750621e-02 | 1.561 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 2.750621e-02 | 1.561 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 3.109986e-02 | 1.507 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 3.123537e-02 | 1.505 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.280092e-02 | 1.484 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.547535e-02 | 1.594 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 3.487276e-02 | 1.458 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.973593e-02 | 1.527 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 3.203508e-02 | 1.494 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 2.630729e-02 | 1.580 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 2.534775e-02 | 1.596 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 3.203508e-02 | 1.494 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 2.561826e-02 | 1.591 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 3.440188e-02 | 1.463 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.534775e-02 | 1.596 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 3.523017e-02 | 1.453 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 2.514602e-02 | 1.600 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 3.933142e-02 | 1.405 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 3.933142e-02 | 1.405 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 3.933142e-02 | 1.405 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 4.189073e-02 | 1.378 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 4.189073e-02 | 1.378 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 4.243384e-02 | 1.372 | 1 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 4.349502e-02 | 1.362 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 4.349502e-02 | 1.362 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 4.349502e-02 | 1.362 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 4.349502e-02 | 1.362 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 4.349502e-02 | 1.362 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 4.349502e-02 | 1.362 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 4.349502e-02 | 1.362 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 4.349502e-02 | 1.362 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 4.349502e-02 | 1.362 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 4.349502e-02 | 1.362 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 4.349502e-02 | 1.362 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 4.349502e-02 | 1.362 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 4.451083e-02 | 1.352 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 4.451083e-02 | 1.352 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 4.451083e-02 | 1.352 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 4.590505e-02 | 1.338 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 4.719008e-02 | 1.326 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 4.719008e-02 | 1.326 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 4.992688e-02 | 1.302 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 4.992688e-02 | 1.302 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 5.271963e-02 | 1.278 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 5.271963e-02 | 1.278 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 5.271963e-02 | 1.278 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 5.366088e-02 | 1.270 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 5.407154e-02 | 1.267 | 0 | 0 |
| Signaling by plasma membrane FGFR1 fusions | R-HSA-8853336 | 5.407154e-02 | 1.267 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 5.407154e-02 | 1.267 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 5.407154e-02 | 1.267 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 6.065239e-02 | 1.217 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 6.065239e-02 | 1.217 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 6.083944e-02 | 1.216 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 6.141820e-02 | 1.212 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 6.430023e-02 | 1.192 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 6.430023e-02 | 1.192 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 6.441949e-02 | 1.191 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 6.453175e-02 | 1.190 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 6.453175e-02 | 1.190 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 7.056597e-02 | 1.151 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 7.056597e-02 | 1.151 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 7.056597e-02 | 1.151 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 7.056597e-02 | 1.151 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 7.206051e-02 | 1.142 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 7.370834e-02 | 1.132 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 7.487693e-02 | 1.126 | 0 | 0 |
| FGFR1c and Klotho ligand binding and activation | R-HSA-190374 | 7.487693e-02 | 1.126 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 7.487693e-02 | 1.126 | 0 | 0 |
| Biosynthesis of DPAn-3-derived 13-series resolvins | R-HSA-9026403 | 7.487693e-02 | 1.126 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 7.487693e-02 | 1.126 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 7.689496e-02 | 1.114 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 7.689496e-02 | 1.114 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 7.957365e-02 | 1.099 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 8.012448e-02 | 1.096 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 8.510834e-02 | 1.070 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 9.522722e-02 | 1.021 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 9.522722e-02 | 1.021 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.052348e-01 | 0.978 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 1.052348e-01 | 0.978 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 1.052348e-01 | 0.978 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 1.151323e-01 | 0.939 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 1.151323e-01 | 0.939 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 1.151323e-01 | 0.939 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 1.151323e-01 | 0.939 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 1.249209e-01 | 0.903 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 1.249209e-01 | 0.903 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.249209e-01 | 0.903 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 1.346019e-01 | 0.871 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 1.630103e-01 | 0.788 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 1.630103e-01 | 0.788 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 1.217655e-01 | 0.914 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.518474e-01 | 0.819 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.595828e-01 | 0.797 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 1.249209e-01 | 0.903 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 1.151323e-01 | 0.939 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.346019e-01 | 0.871 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 1.595828e-01 | 0.797 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.249209e-01 | 0.903 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.073508e-01 | 0.969 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.059178e-01 | 0.975 | 0 | 0 |
| Protein folding | R-HSA-391251 | 1.059178e-01 | 0.975 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.073508e-01 | 0.969 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 8.510834e-02 | 1.070 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.911323e-02 | 1.004 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.911323e-02 | 1.004 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.911323e-02 | 1.004 | 0 | 0 |
| Cam-PDE 1 activation | R-HSA-111957 | 8.510834e-02 | 1.070 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 8.510834e-02 | 1.070 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 1.151323e-01 | 0.939 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 1.441763e-01 | 0.841 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 1.441763e-01 | 0.841 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.630103e-01 | 0.788 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 9.005729e-02 | 1.045 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 1.105492e-01 | 0.956 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.003299e-01 | 0.999 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 1.249209e-01 | 0.903 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 1.557057e-01 | 0.808 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.005729e-02 | 1.045 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 9.686999e-02 | 1.014 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 9.686999e-02 | 1.014 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.114482e-01 | 0.953 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 1.151323e-01 | 0.939 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 1.151323e-01 | 0.939 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 1.249209e-01 | 0.903 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 1.346019e-01 | 0.871 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 1.536454e-01 | 0.813 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 1.536454e-01 | 0.813 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.536454e-01 | 0.813 | 0 | 0 |
| Biosynthesis of DPAn-3-derived protectins and resolvins | R-HSA-9026286 | 1.630103e-01 | 0.788 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.630103e-01 | 0.788 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 8.670694e-02 | 1.062 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 1.207793e-01 | 0.918 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 1.207793e-01 | 0.918 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 9.522722e-02 | 1.021 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 1.249209e-01 | 0.903 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 1.346019e-01 | 0.871 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 1.346019e-01 | 0.871 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 1.536454e-01 | 0.813 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 1.536454e-01 | 0.813 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 1.536454e-01 | 0.813 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 1.128939e-01 | 0.947 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.301846e-01 | 0.885 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 8.510834e-02 | 1.070 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 9.522722e-02 | 1.021 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 1.249209e-01 | 0.903 | 0 | 0 |
| Biosynthesis of DPAn-3-derived maresins | R-HSA-9026290 | 1.441763e-01 | 0.841 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 1.225383e-01 | 0.912 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 1.249209e-01 | 0.903 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 1.073508e-01 | 0.969 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 1.366193e-01 | 0.864 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 1.398742e-01 | 0.854 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 8.670694e-02 | 1.062 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 1.298214e-01 | 0.887 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.595828e-01 | 0.797 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 1.181180e-01 | 0.928 | 1 | 1 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.187901e-01 | 0.925 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 1.043180e-01 | 0.982 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.073508e-01 | 0.969 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 1.038239e-01 | 0.984 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 9.005729e-02 | 1.045 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.328683e-01 | 0.877 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 1.441763e-01 | 0.841 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.273500e-01 | 0.895 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 8.339557e-02 | 1.079 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 1.209714e-01 | 0.917 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 9.344539e-02 | 1.029 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 9.344539e-02 | 1.029 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 1.634777e-01 | 0.787 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.673896e-01 | 0.776 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.711668e-01 | 0.767 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 1.722721e-01 | 0.764 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 1.722721e-01 | 0.764 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 1.722721e-01 | 0.764 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 1.722721e-01 | 0.764 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 1.722721e-01 | 0.764 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 1.722721e-01 | 0.764 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 1.722721e-01 | 0.764 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 1.722721e-01 | 0.764 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.734110e-01 | 0.761 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 1.752609e-01 | 0.756 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 1.752609e-01 | 0.756 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 1.752609e-01 | 0.756 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 1.752609e-01 | 0.756 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 1.752609e-01 | 0.756 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.754007e-01 | 0.756 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 1.792187e-01 | 0.747 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 1.792187e-01 | 0.747 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.796867e-01 | 0.745 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 1.814320e-01 | 0.741 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 1.814320e-01 | 0.741 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 1.814320e-01 | 0.741 | 0 | 0 |
| Biosynthesis of E-series 18(R)-resolvins | R-HSA-9023661 | 1.814320e-01 | 0.741 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.814320e-01 | 0.741 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.814320e-01 | 0.741 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 1.814320e-01 | 0.741 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.814320e-01 | 0.741 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 1.814320e-01 | 0.741 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 1.831902e-01 | 0.737 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 1.831902e-01 | 0.737 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 1.871746e-01 | 0.728 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 1.904912e-01 | 0.720 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 1.904912e-01 | 0.720 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.904912e-01 | 0.720 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 1.904912e-01 | 0.720 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 1.904912e-01 | 0.720 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.904912e-01 | 0.720 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 1.904912e-01 | 0.720 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 1.911711e-01 | 0.719 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 1.911711e-01 | 0.719 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 1.951791e-01 | 0.710 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.964005e-01 | 0.707 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.994506e-01 | 0.700 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.994506e-01 | 0.700 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 1.994506e-01 | 0.700 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.994506e-01 | 0.700 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 1.994506e-01 | 0.700 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 1.994506e-01 | 0.700 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.032263e-01 | 0.692 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.072641e-01 | 0.683 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 2.083114e-01 | 0.681 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 2.083114e-01 | 0.681 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 2.083114e-01 | 0.681 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 2.083114e-01 | 0.681 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 2.083114e-01 | 0.681 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 2.083114e-01 | 0.681 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 2.113104e-01 | 0.675 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 2.170746e-01 | 0.663 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 2.170746e-01 | 0.663 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 2.170746e-01 | 0.663 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 2.170746e-01 | 0.663 | 0 | 0 |
| Biosynthesis of aspirin-triggered D-series resolvins | R-HSA-9020265 | 2.170746e-01 | 0.663 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 2.194260e-01 | 0.659 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 2.194260e-01 | 0.659 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 2.194260e-01 | 0.659 | 0 | 0 |
| Biosynthesis of Lipoxins (LX) | R-HSA-2142700 | 2.257414e-01 | 0.646 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 2.257414e-01 | 0.646 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 2.257414e-01 | 0.646 | 0 | 0 |
| PKA activation | R-HSA-163615 | 2.257414e-01 | 0.646 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.257414e-01 | 0.646 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 2.257414e-01 | 0.646 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 2.275679e-01 | 0.643 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 2.343128e-01 | 0.630 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 2.343128e-01 | 0.630 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 2.343128e-01 | 0.630 | 0 | 0 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 2.343128e-01 | 0.630 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 2.343128e-01 | 0.630 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 2.357310e-01 | 0.628 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 2.398189e-01 | 0.620 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 2.427899e-01 | 0.615 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 2.427899e-01 | 0.615 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.427899e-01 | 0.615 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 2.427899e-01 | 0.615 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 2.427899e-01 | 0.615 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 2.427899e-01 | 0.615 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 2.427899e-01 | 0.615 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 2.439104e-01 | 0.613 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 2.480048e-01 | 0.606 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 2.511736e-01 | 0.600 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 2.511736e-01 | 0.600 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 2.511736e-01 | 0.600 | 0 | 0 |
| Biosynthesis of E-series 18(S)-resolvins | R-HSA-9018896 | 2.511736e-01 | 0.600 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.511736e-01 | 0.600 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 2.511736e-01 | 0.600 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 2.511736e-01 | 0.600 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 2.511736e-01 | 0.600 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 2.521015e-01 | 0.598 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 2.521015e-01 | 0.598 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 2.521015e-01 | 0.598 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 2.562001e-01 | 0.591 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 2.594649e-01 | 0.586 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 2.594649e-01 | 0.586 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.594649e-01 | 0.586 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 2.594649e-01 | 0.586 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 2.594649e-01 | 0.586 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.594649e-01 | 0.586 | 0 | 0 |
| Biosynthesis of D-series resolvins | R-HSA-9018676 | 2.676650e-01 | 0.572 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.676650e-01 | 0.572 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 2.676650e-01 | 0.572 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 2.757748e-01 | 0.559 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 2.757748e-01 | 0.559 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 2.757748e-01 | 0.559 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 2.757748e-01 | 0.559 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 2.757748e-01 | 0.559 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 2.833131e-01 | 0.548 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 2.837953e-01 | 0.547 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 2.837953e-01 | 0.547 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 2.837953e-01 | 0.547 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 2.837953e-01 | 0.547 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 2.837953e-01 | 0.547 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 2.843096e-01 | 0.546 | 1 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 2.848971e-01 | 0.545 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.889918e-01 | 0.539 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 2.889918e-01 | 0.539 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 2.917274e-01 | 0.535 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 2.917274e-01 | 0.535 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 2.917274e-01 | 0.535 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 2.917274e-01 | 0.535 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 2.917274e-01 | 0.535 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 2.917274e-01 | 0.535 | 0 | 0 |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | R-HSA-9027604 | 2.917274e-01 | 0.535 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 2.917274e-01 | 0.535 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 2.917274e-01 | 0.535 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 2.930839e-01 | 0.533 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 2.943846e-01 | 0.531 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 2.995722e-01 | 0.523 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 2.995722e-01 | 0.523 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 2.995722e-01 | 0.523 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 3.012584e-01 | 0.521 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 3.073306e-01 | 0.512 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 3.073306e-01 | 0.512 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 3.073306e-01 | 0.512 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 3.073306e-01 | 0.512 | 0 | 0 |
| Biosynthesis of DPAn-3 SPMs | R-HSA-9025094 | 3.073306e-01 | 0.512 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 3.134897e-01 | 0.504 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 3.150035e-01 | 0.502 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 3.150035e-01 | 0.502 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 3.150035e-01 | 0.502 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 3.150035e-01 | 0.502 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 3.150035e-01 | 0.502 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 3.150035e-01 | 0.502 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 3.150035e-01 | 0.502 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 3.175571e-01 | 0.498 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 3.225919e-01 | 0.491 | 0 | 0 |
| Biosynthesis of EPA-derived SPMs | R-HSA-9018679 | 3.225919e-01 | 0.491 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 3.225919e-01 | 0.491 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 3.225919e-01 | 0.491 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 3.225919e-01 | 0.491 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 3.300967e-01 | 0.481 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 3.300967e-01 | 0.481 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 3.300967e-01 | 0.481 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 3.300967e-01 | 0.481 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 3.300967e-01 | 0.481 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 3.321703e-01 | 0.479 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 3.375188e-01 | 0.472 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 3.375188e-01 | 0.472 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 3.375188e-01 | 0.472 | 0 | 0 |
| Biosynthesis of DPA-derived SPMs | R-HSA-9018683 | 3.375188e-01 | 0.472 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 3.375188e-01 | 0.472 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 3.375188e-01 | 0.472 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 3.375188e-01 | 0.472 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.378043e-01 | 0.471 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 3.418333e-01 | 0.466 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 3.418333e-01 | 0.466 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 3.448591e-01 | 0.462 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 3.448591e-01 | 0.462 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 3.448591e-01 | 0.462 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 3.448591e-01 | 0.462 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.521185e-01 | 0.453 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 3.521185e-01 | 0.453 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 3.521185e-01 | 0.453 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 3.521185e-01 | 0.453 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 3.521185e-01 | 0.453 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 3.578698e-01 | 0.446 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 3.592980e-01 | 0.445 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 3.592980e-01 | 0.445 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.592980e-01 | 0.445 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 3.592980e-01 | 0.445 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 3.592980e-01 | 0.445 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 3.658361e-01 | 0.437 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 3.663983e-01 | 0.436 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 3.663983e-01 | 0.436 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 3.663983e-01 | 0.436 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 3.663983e-01 | 0.436 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 3.734204e-01 | 0.428 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.734204e-01 | 0.428 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 3.734204e-01 | 0.428 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 3.734204e-01 | 0.428 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 3.777141e-01 | 0.423 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 3.803651e-01 | 0.420 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 3.803651e-01 | 0.420 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 3.803651e-01 | 0.420 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 3.803651e-01 | 0.420 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 3.803651e-01 | 0.420 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 3.816533e-01 | 0.418 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 3.816533e-01 | 0.418 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 3.855820e-01 | 0.414 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 3.855820e-01 | 0.414 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 3.872332e-01 | 0.412 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 3.872332e-01 | 0.412 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 3.894999e-01 | 0.409 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 3.934069e-01 | 0.405 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 3.940256e-01 | 0.404 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 4.007432e-01 | 0.397 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 4.007432e-01 | 0.397 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.007432e-01 | 0.397 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 4.011868e-01 | 0.397 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 4.073867e-01 | 0.390 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 4.073867e-01 | 0.390 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 4.073867e-01 | 0.390 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 4.073867e-01 | 0.390 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 4.073867e-01 | 0.390 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 4.073867e-01 | 0.390 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 4.073867e-01 | 0.390 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 4.127686e-01 | 0.384 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 4.139569e-01 | 0.383 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 4.139569e-01 | 0.383 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 4.204286e-01 | 0.376 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 4.204547e-01 | 0.376 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 4.242396e-01 | 0.372 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 4.242396e-01 | 0.372 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 4.268809e-01 | 0.370 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 4.280377e-01 | 0.369 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 4.332362e-01 | 0.363 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 4.332362e-01 | 0.363 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 4.332362e-01 | 0.363 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 4.395214e-01 | 0.357 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 4.395214e-01 | 0.357 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 4.395214e-01 | 0.357 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 4.395214e-01 | 0.357 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 4.395214e-01 | 0.357 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 4.395214e-01 | 0.357 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 4.400216e-01 | 0.357 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 4.430978e-01 | 0.354 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 4.457373e-01 | 0.351 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 4.457373e-01 | 0.351 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 4.457373e-01 | 0.351 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 4.457373e-01 | 0.351 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 4.487223e-01 | 0.348 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 4.518847e-01 | 0.345 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 4.518847e-01 | 0.345 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 4.518847e-01 | 0.345 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 4.518847e-01 | 0.345 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 4.518847e-01 | 0.345 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 4.518847e-01 | 0.345 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 4.579642e-01 | 0.339 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 4.639767e-01 | 0.334 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 4.639767e-01 | 0.334 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 4.639767e-01 | 0.334 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 4.652727e-01 | 0.332 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 4.699228e-01 | 0.328 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 4.699228e-01 | 0.328 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 4.816191e-01 | 0.317 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 4.869225e-01 | 0.313 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.873706e-01 | 0.312 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 4.873706e-01 | 0.312 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 4.873706e-01 | 0.312 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 4.873706e-01 | 0.312 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.904779e-01 | 0.309 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 4.930587e-01 | 0.307 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 4.930587e-01 | 0.307 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 4.930587e-01 | 0.307 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 4.930587e-01 | 0.307 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 4.986839e-01 | 0.302 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 5.042472e-01 | 0.297 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 5.080225e-01 | 0.294 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 5.097490e-01 | 0.293 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 5.097490e-01 | 0.293 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 5.097490e-01 | 0.293 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 5.097490e-01 | 0.293 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 5.097490e-01 | 0.293 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 5.097490e-01 | 0.293 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 5.151901e-01 | 0.288 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 5.151901e-01 | 0.288 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 5.188831e-01 | 0.285 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 5.205711e-01 | 0.284 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 5.242918e-01 | 0.280 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 5.251715e-01 | 0.280 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 5.258928e-01 | 0.279 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 5.258928e-01 | 0.279 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 5.258928e-01 | 0.279 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 5.258928e-01 | 0.279 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 5.311557e-01 | 0.275 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 5.319184e-01 | 0.274 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 5.415078e-01 | 0.266 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 5.415078e-01 | 0.266 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 5.415078e-01 | 0.266 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 5.465983e-01 | 0.262 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 5.465983e-01 | 0.262 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 5.465983e-01 | 0.262 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 5.484997e-01 | 0.261 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 5.516326e-01 | 0.258 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 5.516326e-01 | 0.258 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 5.516326e-01 | 0.258 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 5.582505e-01 | 0.253 | 0 | 0 |
| Translation | R-HSA-72766 | 5.623826e-01 | 0.250 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 5.646680e-01 | 0.248 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 5.646680e-01 | 0.248 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 5.664045e-01 | 0.247 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 5.712200e-01 | 0.243 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 5.804194e-01 | 0.236 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 5.806922e-01 | 0.236 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.806922e-01 | 0.236 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 5.806922e-01 | 0.236 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 5.806922e-01 | 0.236 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 5.835194e-01 | 0.234 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 5.853500e-01 | 0.233 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 5.853500e-01 | 0.233 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 5.853500e-01 | 0.233 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 5.896690e-01 | 0.229 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 5.899563e-01 | 0.229 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 5.945118e-01 | 0.226 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 5.945118e-01 | 0.226 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 5.990169e-01 | 0.223 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 6.034722e-01 | 0.219 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 6.078783e-01 | 0.216 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 6.122251e-01 | 0.213 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 6.165449e-01 | 0.210 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 6.165449e-01 | 0.210 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 6.165449e-01 | 0.210 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 6.199405e-01 | 0.208 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 6.250211e-01 | 0.204 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 6.250211e-01 | 0.204 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 6.291890e-01 | 0.201 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 6.291890e-01 | 0.201 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 6.291890e-01 | 0.201 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 6.308343e-01 | 0.200 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 6.308343e-01 | 0.200 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 6.414184e-01 | 0.193 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 6.454051e-01 | 0.190 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 6.493477e-01 | 0.188 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 6.493477e-01 | 0.188 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.493477e-01 | 0.188 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 6.493477e-01 | 0.188 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 6.532467e-01 | 0.185 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 6.571026e-01 | 0.182 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 6.609158e-01 | 0.180 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 6.684163e-01 | 0.175 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 6.821750e-01 | 0.166 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 6.829258e-01 | 0.166 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 6.864534e-01 | 0.163 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 6.864778e-01 | 0.163 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 6.933919e-01 | 0.159 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 6.968037e-01 | 0.157 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.968037e-01 | 0.157 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 7.081473e-01 | 0.150 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 7.100775e-01 | 0.149 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 7.100775e-01 | 0.149 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 7.100775e-01 | 0.149 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 7.127906e-01 | 0.147 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 7.164961e-01 | 0.145 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 7.227733e-01 | 0.141 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 7.227733e-01 | 0.141 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 7.289123e-01 | 0.137 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 7.289123e-01 | 0.137 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 7.307521e-01 | 0.136 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 7.349161e-01 | 0.134 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 7.362886e-01 | 0.133 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.378682e-01 | 0.132 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 7.393722e-01 | 0.131 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 7.414903e-01 | 0.130 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 7.436748e-01 | 0.129 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 7.436748e-01 | 0.129 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 7.630085e-01 | 0.117 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 7.670898e-01 | 0.115 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 7.682610e-01 | 0.114 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 7.733978e-01 | 0.112 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 7.784214e-01 | 0.109 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 7.808635e-01 | 0.107 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 7.833342e-01 | 0.106 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 7.857498e-01 | 0.105 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 7.974320e-01 | 0.098 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 8.063199e-01 | 0.093 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 8.189297e-01 | 0.087 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 8.229489e-01 | 0.085 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 8.249250e-01 | 0.084 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 8.344817e-01 | 0.079 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 8.417520e-01 | 0.075 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 8.434530e-01 | 0.074 | 0 | 0 |
| S Phase | R-HSA-69242 | 8.435194e-01 | 0.074 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 8.435194e-01 | 0.074 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 8.435194e-01 | 0.074 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 8.468547e-01 | 0.072 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 8.520662e-01 | 0.070 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 8.553535e-01 | 0.068 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 8.569806e-01 | 0.067 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 8.601487e-01 | 0.065 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 8.692700e-01 | 0.061 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 8.805178e-01 | 0.055 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 8.805178e-01 | 0.055 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 8.908028e-01 | 0.050 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 8.967787e-01 | 0.047 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 8.971603e-01 | 0.047 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.024293e-01 | 0.045 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 9.046025e-01 | 0.044 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.067275e-01 | 0.043 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 9.109390e-01 | 0.041 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.157222e-01 | 0.038 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.166667e-01 | 0.038 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.392375e-01 | 0.027 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.432184e-01 | 0.025 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.526011e-01 | 0.021 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 9.604569e-01 | 0.018 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 9.646898e-01 | 0.016 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.785676e-01 | 0.009 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.892888e-01 | 0.005 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.909757e-01 | 0.004 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.932172e-01 | 0.003 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 9.935940e-01 | 0.003 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 9.978699e-01 | 0.001 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 9.994826e-01 | 0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 9.996664e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.998695e-01 | 0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 9.999996e-01 | 0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
