DYRK2
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0MZ66 | S494 | Sugiyama | SHTN1 KIAA1598 | EtELERILRRRKVtAEADsssPtGILAtsEsKsMPVLGsVs |
| A0MZ66 | S532 | Sugiyama | SHTN1 KIAA1598 | sVssVTKTALNKKTLEAEFNsPsPPtPEPGEGPRKLEGCTS |
| A0MZ66 | T537 | Sugiyama | SHTN1 KIAA1598 | TKTALNKKTLEAEFNsPsPPtPEPGEGPRKLEGCTSSKVTF |
| A4FU28 | S140 | Sugiyama | CTAGE9 | AAAEEARSLEATCEKLSRsNsELEDEILCLEKDLKEEKSKH |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A6NMY6 | S22 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | stVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNI |
| O00115 | S70 | Sugiyama | DNASE2 DNASE2A DNL2 | QYKyLDEssGGWRDGRALINsPEGAVGRSLQPLyRSNTSQL |
| O00116 | S65 | Sugiyama | AGPS AAG5 | LLGRPREALSTNECKARRAAsAAtAAPtAtPAAQEsGtIPK |
| O00116 | T72 | Sugiyama | AGPS AAG5 | ALSTNECKARRAAsAAtAAPtAtPAAQEsGtIPKKRQEVMK |
| O00154 | S182 | Sugiyama | ACOT7 BACH | YVPLSLKNVDKVLEVPPVVysRQEQEEEGRKRyEAQKLERM |
| O00178 | S12 | Sugiyama | GTPBP1 | _________MATERsRsAMDsPVPAsMFAPEPssPGAARAA |
| O00193 | S17 | Sugiyama | SMAP C11orf58 | ____MsAARESHPHGVKRsAsPDDDLGssNWEAADLGNEER |
| O00232 | S335 | Sugiyama | PSMD12 | MRWSTLVEDYGMELRKGsLEsPAtDVFGsTEEGEKRWKDLK |
| O00410 | S974 | Sugiyama | IPO5 KPNB3 RANBP5 | VIQSADSKTKENVNAtENCIsAVGKIMKFKPDCVNVEEVLP |
| O00429 | S126 | Sugiyama | DNM1L DLP1 DRP1 | EIRQEIENETERISGNNKGVsPEPIHLKIFSPNVVNLTLVD |
| O00763 | S246 | Sugiyama | ACACB ACC2 ACCB | LVKRGREHKKLDLHRDFTVAsPAEFVTRFGGDRVIEKVLIA |
| O14579 | S307 | Sugiyama | COPE | IKEYQAKENDFDRLVLQyAPsA___________________ |
| O14818 | S11 | Sugiyama | PSMA7 HSPC | __________MsYDRAItVFsPDGHLFQVEYAQEAVKKGst |
| O14818 | T8 | Sugiyama | PSMA7 HSPC | _____________MsYDRAItVFsPDGHLFQVEYAQEAVKK |
| O15067 | S1062 | Sugiyama | PFAS KIAA0361 | SYCLPPTFPKAsVPREPGGPsPRVAILREEGSNGDREMADA |
| O15160 | S258 | Sugiyama | POLR1C POLR1E | DITLLEPVEGEAAEELSRCFsPGVIEVQEVQGKKVARVANP |
| O15230 | S2648 | Sugiyama | LAMA5 KIAA0533 KIAA1907 | KIAHAKAVAAEAQDTATRVQsQLQAMQENVERWQGQYEGLR |
| O15355 | S240 | Sugiyama | PPM1G PPM1C | RGTEAGQVGEPGIPtGEAGPsCssAsDKLPRVAKSKFFEDS |
| O15355 | T234 | Sugiyama | PPM1G PPM1C | FssNsERGTEAGQVGEPGIPtGEAGPsCssAsDKLPRVAKS |
| O15372 | S290 | Sugiyama | EIF3H EIF3S3 | QQQQKHQYQQRRQQENMQRQsRGEPPLPEEDLsKLFKPPQP |
| O15460 | S531 | Sugiyama | P4HA2 UNQ290/PRO330 | KWVSNKWFHERGQEFLRPCGstEVD________________ |
| O43175 | S251 | Sugiyama | PHGDH PGDH3 | VVNCARGGIVDEGALLRALQsGQCAGAALDVFTEEPPRDRA |
| O43175 | T78 | Sugiyama | PHGDH PGDH3 | KVTADVINAAEKLQVVGRAGtGVDNVDLEAAtRKGILVMNT |
| O43175 | T89 | Sugiyama | PHGDH PGDH3 | KLQVVGRAGtGVDNVDLEAAtRKGILVMNTPNGNSLSAAEL |
| O43255 | S16 | SIGNOR|EPSD|PSP | SIAH2 | _____MSRPsstGPsANKPCsKQPPPQPQHtPsPAAPPAAA |
| O43255 | S28 | SIGNOR|EPSD|PSP | SIAH2 | GPsANKPCsKQPPPQPQHtPsPAAPPAAATISAAGPGSSAV |
| O43255 | S68 | SIGNOR|EPSD|PSP | SIAH2 | VPAAAAVISGPGGGGGAGPVsPQHHELTSLFECPVCFDYVL |
| O43255 | T119 | SIGNOR|EPSD|PSP | SIAH2 | LVCNQCRQKLSCCPTCRGALtPSIRNLAMEKVASAVLFPCK |
| O43255 | T26 | SIGNOR|EPSD|PSP | SIAH2 | stGPsANKPCsKQPPPQPQHtPsPAAPPAAATISAAGPGSS |
| O43488 | S40 | Sugiyama | AKR7A2 AFAR AFAR1 AKR7 | SPPPEARALAMSRPPPPRVAsVLGTMEMGRRMDAPAsAAAV |
| O43491 | S386 | Sugiyama | EPB41L2 | TQTKELEEKVAELHKTHRGLsPAQADsQFLENAKRLsMYGV |
| O43633 | S203 | Sugiyama | CHMP2A BC2 CHMP2 | PSTGGSLSVAAGGKKAEAAAsALADADADLEERLKNLRRD_ |
| O43765 | S77 | Sugiyama | SGTA SGT SGT1 | TLPEIFEAAATGKEMPQDLRsPARtPPsEEDsAEAERLKTE |
| O43765 | T81 | Sugiyama | SGTA SGT SGT1 | IFEAAATGKEMPQDLRsPARtPPsEEDsAEAERLKTEGNEQ |
| O43815 | S229 | Sugiyama | STRN | TEAEVKETAMIAKSELtDsAsVLDNFKFLEsAAADFsDEDE |
| O43852 | T65 | Sugiyama | CALU | FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD |
| O60216 | S454 | Sugiyama | RAD21 HR21 KIAA0078 NXP1 SCC1 | HQQRDVIDEPIIEEPsRLQEsVMEAsRTNIDESAMPPPPPQ |
| O60245 | S241 | Sugiyama | PCDH7 BHPCDH | GSKRRLDASEGGGGTNPGGRsSVFELQVADtPDGEKQPQLI |
| O60245 | T251 | Sugiyama | PCDH7 BHPCDH | GGGGTNPGGRsSVFELQVADtPDGEKQPQLIVKGALDREQR |
| O60271 | S194 | Sugiyama | SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 | LERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLPAGDG |
| O60333 | S654 | Sugiyama | KIF1B KIAA0591 KIAA1448 | FNHPEQARAEREKtPsAEtPsEPVDWTFAQRELLEKQGIDM |
| O60333 | T647 | Sugiyama | KIF1B KIAA0591 KIAA1448 | GKNHVFRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELL |
| O60333 | T652 | Sugiyama | KIF1B KIAA0591 KIAA1448 | FRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELLEKQGI |
| O60573 | T73 | Sugiyama | EIF4E2 EIF4EL3 | EHPLQYNYTFWYSRRtPGRPtsSQSyEQNIKQIGTFASVEQ |
| O60664 | S175 | Sugiyama | PLIN3 M6PRBP1 TIP47 | RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK |
| O60664 | S179 | Sugiyama | PLIN3 M6PRBP1 TIP47 | QSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGKsEEW |
| O60664 | S225 | Sugiyama | PLIN3 M6PRBP1 TIP47 | PLTDAELARIAtsLDGFDVAsVQQQRQEQSyFVRLGsLSER |
| O60664 | T216 | Sugiyama | PLIN3 M6PRBP1 TIP47 | sEEWADNHLPLTDAELARIAtsLDGFDVAsVQQQRQEQSyF |
| O60701 | T185 | Sugiyama | UGDH | EGTAIKDLKNPDRVLIGGDEtPEGQRAVQALCAVYEHWVPR |
| O60716 | S252 | Sugiyama | CTNND1 KIAA0384 | sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL |
| O60716 | S861 | Sugiyama | CTNND1 KIAA0384 | KEGWKKsDFQVNLNNAsRsQssHsyDDstLPLIDRNQKsDK |
| O60749 | S119 | Sugiyama | SNX2 TRG9 | AVtPVtPttLIAPRIESKsMsAPVIFDRsREEIEEEANGDI |
| O60749 | S365 | Sugiyama | SNX2 TRG9 | AKSAAMLGNsEDHTALSRALsQLAEVEEKIDQLHQEQAFAD |
| O60763 | S851 | Sugiyama | USO1 VDP | VQGETETIIATKTTDVEGRLsALLQETKELKNEIKALSEER |
| O60841 | S182 | Sugiyama | EIF5B IF2 KIAA0741 | DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK |
| O75116 | S423 | Sugiyama | ROCK2 KIAA0619 | FVGNQLPFIGFTYYRENLLLsDsPSCRETDSIQSRKNEESQ |
| O75116 | S425 | Sugiyama | ROCK2 KIAA0619 | GNQLPFIGFTYYRENLLLsDsPSCRETDSIQSRKNEESQEI |
| O75131 | S242 | Sugiyama | CPNE3 CPN3 KIAA0636 | SHDLIGTFQTTMTKLKEAsRssPVEFECINEKKRQKKKSYK |
| O75369 | T1259 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | EGKDVFREATTDFTVDSRPLtQVGGDHIKAHIANPSGASTE |
| O75391 | S158 | Sugiyama | SPAG7 | LKELAQRQEEEAAQQGPVVVsPAsDyKDKYSHLIGKGAAKD |
| O75436 | T102 | Sugiyama | VPS26A VPS26 | KSNTHEFVNLVKELALPGELtQSRSYDFEFMQVEKPYESYI |
| O75449 | S109 | GPS6|SIGNOR|EPSD|PSP | KATNA1 | DLPAsEGEVWSMPVPVERRPsPGPRKRQsSQYSDPKSHGNR |
| O75449 | S42 | GPS6|SIGNOR|EPSD|PSP | KATNA1 | YDSAMVYYQGVLDQMNKYLYsVKDTYLQQKWQQVWQEINVE |
| O75449 | T133 | GPS6|SIGNOR|EPSD|PSP | KATNA1 | RKRQsSQYSDPKSHGNRPSTtVRVHRSSAQNVHNDRGKAVR |
| O75533 | T223 | Sugiyama | SF3B1 SAP155 | tADQtPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsE |
| O75533 | T227 | Sugiyama | SF3B1 SAP155 | tPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsEtPGA |
| O75534 | S584 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | YSLSKGKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRP |
| O75534 | T589 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | GKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRPLRSVD |
| O75822 | T109 | Sugiyama | EIF3J EIF3S1 PRO0391 | KKRQEEIKKRLEEPEEPKVLtPEEQLADKLRLKKLQEEsDL |
| O76021 | S314 | Sugiyama | RSL1D1 CATX11 CSIG PBK1 L12 | RNFEKQKERKKKRQQARKtAsVLsKDDVAPEsGDtTVKKPE |
| O94808 | S202 | Sugiyama | GFPT2 | FALVFKSVHYPGEAVATRRGsPLLIGVRSKYKLSTEQIPIL |
| O94842 | S575 | Sugiyama | TOX4 C14orf92 KIAA0737 | DVELVSGSPVALsPQPRCVRsGCENPPIVSKDWDNEyCSNE |
| O94979 | S799 | Sugiyama | SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334 | IMQLRDRLCRAQGEPVAGHEsPKIPyEKQQLPKGRPGPVAG |
| O94992 | S299 | Sugiyama | HEXIM1 CLP1 EDG1 HIS1 MAQ1 | LQNMsKQELIKEyLELEKCLsRMEDENNRLRLESKRLGGDD |
| O95218 | S65 | Sugiyama | ZRANB2 ZIS ZNF265 | MKAGGtEIGKtLAEKSRGLFsANDWQCKTCsNVNWARRsEC |
| O95757 | S586 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | DRLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGK |
| O95816 | S208 | Sugiyama | BAG2 | IKLLEHSKGAGSKTLQQNAEsRFN_________________ |
| O95831 | S100 | Sugiyama | AIFM1 AIF PDCD8 | AGAYAYKTMKEDEKRyNERIsGLGLtPEQKQKKAALsAsEG |
| O95831 | T105 | Sugiyama | AIFM1 AIF PDCD8 | YKTMKEDEKRyNERIsGLGLtPEQKQKKAALsAsEGEEVPQ |
| O95831 | Y95 | Sugiyama | AIFM1 AIF PDCD8 | LSTVGAGAYAYKTMKEDEKRyNERIsGLGLtPEQKQKKAAL |
| O95863 | S104 | PSP | SNAI1 SNAH | RVAELTSLsDEDsGKGsQPPsPPsPAPsSFSsTSVsSLEAE |
| P00338 | S105 | Sugiyama | LDHA PIG19 | VTANsKLVIItAGARQQEGEsRLNLVQRNVNIFKFIIPNVV |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S319 | Sugiyama | LDHA PIG19 | GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______ |
| P00367 | T410 | Sugiyama | GLUD1 GLUD | KSNAPRVKAKIIAEGANGPttPEADKIFLERNIMVIPDLYL |
| P00491 | S176 | Sugiyama | PNP NP | GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA |
| P00558 | S174 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P00558 | S364 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EWEAFARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWN |
| P00558 | T363 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | FEWEAFARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKW |
| P00558 | T369 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV |
| P01023 | S593 | Sugiyama | A2M CPAMD5 FWP007 | SPSQSLPASHAHLRVTAAPQsVCALRAVDQSVLLMKPDAEL |
| P02545 | S390 | Sugiyama | LMNA LMN1 | DMEIHAYRKLLEGEEERLRLsPsPtsQRsRGRAssHssQtQ |
| P02545 | S392 | Sugiyama | LMNA LMN1 | EIHAYRKLLEGEEERLRLsPsPtsQRsRGRAssHssQtQGG |
| P02786 | S654 | Sugiyama | TFRC | EMGLSLQWLYSARGDFFRATsRLTTDFGNAEKTDRFVMKKL |
| P04049 | S244 | Sugiyama | RAF1 RAF | MPVssQHRystPHAFtFNtssPSSEGSLSQRQRststPNVH |
| P04049 | Y232 | Sugiyama | RAF1 RAF | LTMRRMRESVSRMPVssQHRystPHAFtFNtssPSSEGSLS |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | T344 | Sugiyama | ALDOA ALDA | AQEEYVKRALANsLACQGKytPsGQAGAAAsEsLFVsNHAy |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | T237 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD |
| P04637 | S46 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | TP53 P53 | LPENNVLsPLPsQAMDDLMLsPDDIEQWFtEDPGPDEAPRM |
| P04792 | S83 | Sugiyama | HSPB1 HSP27 HSP28 | IEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNH |
| P05023 | S519 | Sugiyama | ATP1A1 | sEPQHLLVMKGAPERILDRCssILLHGKEQPLDEELKDAFQ |
| P05187 | S153 | Sugiyama | ALPP PLAP | GLSAAARFNQCNTTRGNEVIsVMNRAKKAGKSVGVVTTTRV |
| P05187 | S177 | Sugiyama | ALPP PLAP | RAKKAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADVP |
| P05362 | S43 | Sugiyama | ICAM1 | GPGNAQTSVSPSKVILPRGGsVLVTCstsCDQPKLLGIETP |
| P05362 | S49 | Sugiyama | ICAM1 | TSVSPSKVILPRGGsVLVTCstsCDQPKLLGIETPLPKKEL |
| P05362 | T50 | Sugiyama | ICAM1 | SVSPSKVILPRGGsVLVTCstsCDQPKLLGIETPLPKKELL |
| P05387 | S74 | Sugiyama | RPLP2 D11S2243E RPP2 | VIAQGIGKLAsVPAGGAVAVsAAPGsAAPAAGsAPAAAEEK |
| P05387 | S79 | Sugiyama | RPLP2 D11S2243E RPP2 | IGKLAsVPAGGAVAVsAAPGsAAPAAGsAPAAAEEKKDEKK |
| P05387 | S86 | Sugiyama | RPLP2 D11S2243E RPP2 | PAGGAVAVsAAPGsAAPAAGsAPAAAEEKKDEKKEEsEEsD |
| P05412 | S243 | SIGNOR | JUN | QALKEEPQtVPEMPGEtPPLsPIDMEsQERIKAERKRMRNR |
| P05787 | S404 | Sugiyama | KRT8 CYK8 | LDIEIATYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLS |
| P06733 | S263 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GMDVAASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsF |
| P06733 | S272 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI |
| P06733 | S37 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY |
| P06733 | S40 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK |
| P06733 | T26 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06744 | T109 | Sugiyama | GPI | KINyTEGRAVLHVALRNRsNtPILVDGKDVMPEVNKVLDKM |
| P07195 | S106 | Sugiyama | LDHB | VtANSKIVVVtAGVRQQEGEsRLNLVQRNVNVFKFIIPQIV |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | S320 | Sugiyama | LDHB | GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______ |
| P07195 | T302 | Sugiyama | LDHB | YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07355 | S22 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | stVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNI |
| P07437 | S115 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL |
| P07437 | S168 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | GTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS |
| P07437 | S172 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | ISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSVHQL |
| P07737 | S30 | Sugiyama | PFN1 | NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV |
| P07814 | S739 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV |
| P07814 | T737 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | EKTKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRV |
| P07814 | T745 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | KNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAVQGDVVR |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07900 | S165 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK |
| P07900 | S391 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08195 | S607 | Sugiyama | SLC3A2 MDU1 | ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP |
| P08238 | S160 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK |
| P08238 | S383 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08708 | S89 | Sugiyama | RPS17 RPS17L | ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL |
| P08865 | S75 | Sugiyama | RPSA LAMBR LAMR1 | WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG |
| P08865 | S79 | Sugiyama | RPSA LAMBR LAMR1 | LLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtPI |
| P08865 | T82 | Sugiyama | RPSA LAMBR LAMR1 | ARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtPIAGR |
| P09104 | S37 | Sugiyama | ENO2 | NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09923 | S150 | Sugiyama | ALPI | GLSAAARFNQCNTTRGNEVIsVMNRAKQAGKSVGVVTTTRV |
| P09923 | S174 | Sugiyama | ALPI | RAKQAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMP |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG41 | S140 | Sugiyama | CTAGE8 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| P10696 | S150 | Sugiyama | ALPG ALPPL ALPPL2 | GLSAAARFNQCNTTRGNEVIsVMNRAKKAGKSVGVVTTTRV |
| P10809 | S225 | Sugiyama | HSPD1 HSP60 | KtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVL |
| P10809 | T115 | Sugiyama | HSPD1 HSP60 | AKLVQDVANNtNEEAGDGtttAtVLARSIAKEGFEKISKGA |
| P11047 | S401 | Sugiyama | LAMC1 LAMB2 | RCRENFFRLGNNEACSSCHCsPVGSLSTQCDSyGRCSCKPG |
| P11142 | T38 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P11586 | S129 | Sugiyama | MTHFD1 MTHFC MTHFD | INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P11586 | T378 | Sugiyama | MTHFD1 MTHFC MTHFD | SALERLKHRPDGKyVVVTGItPtPLGEGKSTTTIGLVQALG |
| P11586 | T380 | Sugiyama | MTHFD1 MTHFC MTHFD | LERLKHRPDGKyVVVTGItPtPLGEGKSTTTIGLVQALGAH |
| P11940 | S315 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | NLyVKNLDDGIDDERLRKEFsPFGtItsAKVMMEGGRSKGF |
| P11940 | T321 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | LDDGIDDERLRKEFsPFGtItsAKVMMEGGRSKGFGFVCFs |
| P12270 | S111 | Sugiyama | TPR | ALTEKNKELEIAQDRNIAIQsQFTRTKEELEAEKRDLIRTN |
| P12270 | S648 | Sugiyama | TPR | LHAssLDDVsLAstPKRPstsQtVstPAPVPVIESTEAIEA |
| P12270 | T650 | Sugiyama | TPR | AssLDDVsLAstPKRPstsQtVstPAPVPVIESTEAIEAKA |
| P12270 | T653 | Sugiyama | TPR | LDDVsLAstPKRPstsQtVstPAPVPVIESTEAIEAKAALK |
| P12277 | S163 | Sugiyama | CKB CKBB | PPHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAE |
| P12277 | T35 | Sugiyama | CKB CKBB | PAEDEFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDD |
| P13051 | S64 | Sugiyama | UNG DGU UNG1 UNG15 | AAIPAKKAPAGQEEPGtPPssPLsAEQLDRIQRNKAAALLR |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13639 | S595 | Sugiyama | EEF2 EF2 | PVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGLAE |
| P13667 | S126 | Sugiyama | PDIA4 ERP70 ERP72 | NILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKILKKG |
| P13674 | S395 | Sugiyama | P4HA1 P4HA | TVHYRISKsAWLsGyENPVVsRINMRIQDLTGLDVSTAEEL |
| P13797 | S339 | Sugiyama | PLS3 | PRIDINMsGFNETDDLKRAEsMLQQADKLGCRQFVTPADVV |
| P13798 | S94 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | DSVVFAGPAGNSVETRGELLsREsPSGTMKAVLRKAGGTGP |
| P13798 | S97 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | VFAGPAGNSVETRGELLsREsPSGTMKAVLRKAGGTGPGEE |
| P13861 | S48 | Sugiyama | PRKAR2A PKR2 PRKAR2 | DLVEFAVEYFTRLREARAPAsVLPAAtPRQsLGHPPPEPGP |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P13861 | T54 | Sugiyama | PRKAR2A PKR2 PRKAR2 | VEYFTRLREARAPAsVLPAAtPRQsLGHPPPEPGPDRVADA |
| P13929 | S37 | Sugiyama | ENO3 | NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P14314 | S442 | Sugiyama | PRKCSH G19P1 | EYVYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSA |
| P14314 | T444 | Sugiyama | PRKCSH G19P1 | VYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMK |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S37 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | QLHAAMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRs |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | T44 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | EVDVDGTVEEDLGKSREGsRtDDEVVQREEEAIQLDGLNAs |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14866 | S544 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | LGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLNH |
| P15121 | S264 | Sugiyama | AKR1B1 ALDR1 ALR2 | ttAQVLIRFPMQRNLVVIPKsVtPERIAENFKVFDFELSSQ |
| P15121 | T266 | Sugiyama | AKR1B1 ALDR1 ALR2 | AQVLIRFPMQRNLVVIPKsVtPERIAENFKVFDFELSSQDM |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15311 | T533 | Sugiyama | EZR VIL2 | NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII |
| P15336 | T69 | Sugiyama | ATF2 CREB2 CREBP1 | HEMtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELA |
| P15336 | T71 | Sugiyama | ATF2 CREB2 CREBP1 | MtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELAsP |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P15559 | S82 | Sugiyama | NQO1 DIA4 NMOR1 | DPANFQYPAESVLAYKEGHLsPDIVAEQKKLEAADLVIFQF |
| P15880 | S190 | Sugiyama | RPS2 RPS4 | WGNKIGKPHTVPCKVTGRCGsVLVRLIPAPRGtGIVsAPVP |
| P16070 | T720 | Sugiyama | CD44 LHR MDU2 MDU3 MIC4 | NGEAsKsQEMVHLVNKEssEtPDQFMtADEtRNLQNVDMKI |
| P16278 | S433 | Sugiyama | GLB1 ELNR1 | YGFVLYRTTLPQDCSNPAPLssPLNGVHDRAyVAVDGIPQG |
| P16333 | S89 | Sugiyama | NCK1 NCK | KNLKDTLGIGKVKRKPsVPDsAsPADDsFVDPGERLyDLNM |
| P16333 | S91 | Sugiyama | NCK1 NCK | LKDTLGIGKVKRKPsVPDsAsPADDsFVDPGERLyDLNMPA |
| P17174 | S82 | Sugiyama | GOT1 | ANDNsLNHEyLPILGLAEFRsCAsRLALGDDsPALKEKRVG |
| P17174 | S85 | Sugiyama | GOT1 | NsLNHEyLPILGLAEFRsCAsRLALGDDsPALKEKRVGGVQ |
| P17174 | S93 | Sugiyama | GOT1 | PILGLAEFRsCAsRLALGDDsPALKEKRVGGVQsLGGtGAL |
| P17544 | T51 | Sugiyama | ATF7 ATFA | HEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELA |
| P17544 | T53 | Sugiyama | ATF7 ATFA | MTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELASS |
| P17812 | S210 | Sugiyama | CTPS1 CTPS | GEQKTKPTQNSVRELRGLGLsPDLVVCRCSNPLDTSVKEKI |
| P17812 | S568 | Sugiyama | CTPS1 CTPS | VGRLSHYLQKGCRLsPRDtysDRsGsssPDsEItELKFPsI |
| P17812 | S571 | Sugiyama | CTPS1 CTPS | LSHYLQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD |
| P17812 | S573 | Sugiyama | CTPS1 CTPS | HYLQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD__ |
| P17812 | S574 | Sugiyama | CTPS1 CTPS | YLQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD___ |
| P17812 | S575 | Sugiyama | CTPS1 CTPS | LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____ |
| P17844 | S24 | Sugiyama | DDX5 G17P1 HELR HLR1 | YssDRDRGRDRGFGAPRFGGsRAGPLsGKKFGNPGEKLVKK |
| P17980 | S376 | Sugiyama | PSMC3 TBP1 | MPNEEARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQC |
| P18206 | S795 | Sugiyama | VCL | EDPKFREAVKAASDELsKtIsPMVMDAKAVAGNIsDPGLQK |
| P18615 | S115 | Sugiyama | NELFE RD RDBP | KLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLyEs |
| P18827 | S233 | Sugiyama | SDC1 SDC | FETSGENTAVVAVEPDRRNQsPVDQGAtGAsQGLLDRKEVL |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P20810 | S366 | Sugiyama | CAST | DKDGKPLLPEPEEKPKPRsEsELIDELsEDFDRsECKEKPS |
| P20933 | S49 | Sugiyama | AGA | LVVNTWPFKNATEAAWRALAsGGSALDAVEsGCAMCEREQC |
| P21333 | S1084 | Sugiyama | FLNA FLN FLN1 | PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV |
| P21333 | S2319 | Sugiyama | FLNA FLN FLN1 | VQEPGDyEVsVKFNEEHIPDsPFVVPVAsPsGDARRLtVss |
| P21333 | S2327 | Sugiyama | FLNA FLN FLN1 | VsVKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKV |
| P22059 | T326 | Sugiyama | OSBP OSBP1 | ETLEQLAKQHNHLERAFRGAtVLPANtPGNVGsGKDQCCSG |
| P22059 | T332 | Sugiyama | OSBP OSBP1 | AKQHNHLERAFRGAtVLPANtPGNVGsGKDQCCSGKGDMsD |
| P22059 | T377 | Sugiyama | OSBP OSBP1 | NEFFDAPEIITMPENLGHKRtGsNIsGAssDIsLDEQyKHQ |
| P22234 | S27 | Sugiyama | PAICS ADE2 AIRC PAIS | LNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAGNAARK |
| P22626 | S189 | Sugiyama | HNRNPA2B1 HNRPA2B1 | IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF |
| P22626 | S198 | Sugiyama | HNRNPA2B1 HNRPA2B1 | NGHNAEVRKALsRQEMQEVQssRsGRGGNFGFGDsRGGGGN |
| P22626 | S212 | Sugiyama | HNRNPA2B1 HNRPA2B1 | EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD |
| P22626 | S259 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GFGDGyNGyGGGPGGGNFGGsPGyGGGRGGYGGGGPGYGNQ |
| P22626 | Y353 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GGNyGPGGsGGsGGyGGRsRy____________________ |
| P23588 | S311 | Sugiyama | EIF4B | YRGGGDRYEDRYDRRDDRsWssRDDysRDDYRRDDRGPPQR |
| P23921 | S559 | Sugiyama | RRM1 RR1 | ALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTPTDLW |
| P23921 | S780 | Sugiyama | RRM1 RR1 | KEKVSKEEEEKERNtAAMVCsLENRDECLMCGS________ |
| P23921 | T774 | Sugiyama | RRM1 RR1 | KEKLKDKEKVSKEEEEKERNtAAMVCsLENRDECLMCGS__ |
| P24666 | T47 | Sugiyama | ACP1 | FRKLVTDQNISENWRVDSAAtsGyEIGNPPDYRGQSCMKRH |
| P25205 | S447 | Sugiyama | MCM3 | EQGRVTIAKAGIHARLNARCsVLAAANPVyGRyDQyKTPME |
| P25398 | Y127 | Sugiyama | RPS12 | sCVVVKDYGKESQAKDVIEEyFKCKK_______________ |
| P25705 | T64 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | QKtGtAEMssILEERILGADtsVDLEETGRVLsIGDGIARV |
| P25786 | S14 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | _______MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQGSA |
| P26232 | S654 | Sugiyama | CTNNA2 CAPR | EELEDDsDFEQEDYDVRsRtsVQtEDDQLIAGQsARAIMAQ |
| P27348 | S63 | Sugiyama | YWHAQ | LLsVAyKNVVGGRRSAWRVIsSIEQKTDTSDKKLQLIKDYR |
| P27695 | S135 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | SHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDEEHDQEG |
| P27708 | S1038 | Sugiyama | CAD | QLPNNMAMALHRQQCRVLGtsPEAIDSAENRFKFSRLLDTI |
| P27797 | S35 | Sugiyama | CALR CRTC | AVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGK |
| P27797 | S40 | Sugiyama | CALR CRTC | AVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGKFyGDE |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P27824 | S362 | Sugiyama | CANX | WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK |
| P28066 | S16 | Sugiyama | PSMA5 | _____MFLTRsEyDRGVNtFsPEGRLFQVEyAIEAIKLGST |
| P28066 | S172 | Sugiyama | PSMA5 | QLFHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLK |
| P28066 | S174 | Sugiyama | PSMA5 | FHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEA |
| P28066 | S179 | Sugiyama | PSMA5 | sGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSL |
| P28340 | S60 | Sugiyama | POLD1 POLD | LMEEMEAEHRLQEQEEEELQsVLEGVADGQVPPsAIDPRWL |
| P28340 | S73 | Sugiyama | POLD1 POLD | QEEEELQsVLEGVADGQVPPsAIDPRWLRPTPPALDPQTEP |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | T287 | Sugiyama | TKT | AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP |
| P29692 | S106 | Sugiyama | EEF1D EF1D | sLEVENQsLRGVVQELQQAIsKLEARLNVLEKssPGHRAtA |
| P29692 | S133 | Sugiyama | EEF1D EF1D | NVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPAEDDE |
| P29692 | S37 | Sugiyama | EEF1D EF1D | KYDDAERRFyEQMNGPVAGAsRQENGAsVILRDIARARENI |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29966 | S27 | Sugiyama | MARCKS MACS PRKCSL | KTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAsP |
| P30041 | T177 | Sugiyama | PRDX6 AOP2 KIAA0106 | FDEILRVVISLQLTAEKRVAtPVDWKDGDsVMVLPtIPEEE |
| P30041 | T221 | Sugiyama | PRDX6 AOP2 KIAA0106 | LFPKGVFtKELPSGKKYLRYtPQP_________________ |
| P30041 | T44 | Sugiyama | PRDX6 AOP2 KIAA0106 | RFHDFLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKR |
| P30041 | T48 | Sugiyama | PRDX6 AOP2 KIAA0106 | FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL |
| P30050 | S26 | Sugiyama | RPL12 | DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | S99 | Sugiyama | PEBP1 PBP PEBP | PKYREWHHFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLHR |
| P30101 | T485 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKKKKAQEDL |
| P30304 | S107 | SIGNOR|PSP | CDC25A | DsPGPLDSKENLENPMRRIHsLPQKLLGCsPALKRSHsDSL |
| P30304 | S156 | SIGNOR|PSP | CDC25A | DPDENKENEAFEFKKPVRPVsRGCLHSHGLQEGKDLFTQRQ |
| P30304 | S18 | SIGNOR|PSP | CDC25A | ___MELGPEPPHRRRLLFACsPPPASQPVVKALFGASAAGG |
| P30304 | S185 | SIGNOR|PSP | CDC25A | LQEGKDLFTQRQNsAPARMLsSNERDSSEPGNFIPLFTPQS |
| P30304 | S283 | PSP | CDC25A | sLCssSTRSVLKRPERsQEEsPPGSTKRRKsMsGASPKEST |
| P30304 | S320 | SIGNOR|PSP | CDC25A | KESTNPEKAHETLHQSLSLAssPKGTIENILDNDPRDLIGD |
| P30304 | S321 | SIGNOR|PSP | CDC25A | ESTNPEKAHETLHQSLSLAssPKGTIENILDNDPRDLIGDF |
| P30304 | S88 | SIGNOR|PSP | CDC25A | NSNLQRMGsSEstDsGFCLDsPGPLDSKENLENPMRRIHsL |
| P30533 | S350 | Sugiyama | LRPAP1 A2MRAP | RTKELGYTVKKHLQDLSGRIsRARHNEL_____________ |
| P31327 | S1079 | Sugiyama | CPS1 | QIPNNLAVPLYKNGVKIMGTsPLQIDRAEDRsIFsAVLDEL |
| P31327 | S759 | Sugiyama | CPS1 | AKIALGIPLPEIKNVVSGKTsACFEPSLDyMVtKIPRWDLD |
| P31943 | S269 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH |
| P31943 | Y266 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst |
| P31946 | S145 | Sugiyama | YWHAB | GDYFRyLsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPT |
| P31946 | S65 | Sugiyama | YWHAB | LLsVAyKNVVGARRSsWRVIsSIEQKTERNEKKQQMGKEYR |
| P31948 | T243 | Sugiyama | STIP1 | KQALKEKELGNDAYKKKDFDtALKHYDKAKELDPtNMtyIT |
| P32004 | S1248 | Sugiyama | L1CAM CAML1 MIC5 | QySGKKEKEAAGGNDssGAtsPINPAVALE___________ |
| P33176 | S175 | Sugiyama | KIF5B KNS KNS1 | VHEDKNRVPYVKGCTERFVCsPDEVMDtIDEGKSNRHVAVT |
| P33993 | T254 | Sugiyama | MCM7 CDC47 MCM2 | EMKMQEHSDQVPVGNIPRSItVLVEGENTRIAQPGDHVSVT |
| P34896 | T405 | Sugiyama | SHMT1 | NKNTCPGDRSALRPSGLRLGtPALTSRGLLEKDFQKVAHFI |
| P34897 | S417 | Sugiyama | SHMT2 | ERVLELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFR |
| P34897 | S90 | Sugiyama | SHMT2 | GLELIAsENFCsRAALEALGsCLNNKYSEGYPGKRyyGGAE |
| P34897 | T420 | Sugiyama | SHMT2 | LELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFREDD |
| P34931 | T40 | Sugiyama | HSPA1L | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P34932 | S408 | Sugiyama | HSPA4 APG2 HSPH2 | KVREFSITDVVPYPISLRWNsPAEEGssDCEVFSKNHAAPF |
| P35221 | S655 | Sugiyama | CTNNA1 | PEELDDsDFEtEDFDVRsRtsVQtEDDQLIAGQsARAIMAQ |
| P35579 | S1892 | Sugiyama | MYH9 | LKQLKRQLEEAEEEAQRANAsRRKLQRELEDAtEtADAMNR |
| P35579 | S1915 | Sugiyama | MYH9 | KLQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMA |
| P35580 | S1013 | Sugiyama | MYH10 | QNSKFIKEKKLMEDRIAECssQLAEEEEKAKNLAKIRNKQE |
| P35613 | S279 | Sugiyama | BSG UNQ6505/PRO21383 | TDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQy |
| P35998 | T193 | Sugiyama | PSMC2 MSS1 | TYSDVGGCKEQIEKLREVVEtPLLHPERFVNLGIEPPKGVL |
| P36578 | S55 | Sugiyama | RPL4 RPL1 | DIVNFVHTNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVAR |
| P36578 | T62 | Sugiyama | RPL4 RPL1 | TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG |
| P36871 | S485 | Sugiyama | PGM1 | VYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFRLs |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37837 | S13 | Sugiyama | TALDO1 TAL TALDO TALDOR | ________MsssPVKRQRMEsALDQLKQFTTVVADTGDFHA |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T86 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK |
| P38646 | T87 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKR |
| P39023 | S13 | Sugiyama | RPL3 OK/SW-cl.32 | ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP |
| P39023 | S265 | Sugiyama | RPL3 OK/SW-cl.32 | HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY |
| P40121 | S318 | Sugiyama | CAPG AFCP MCP | GRKANEKERQAALQVAEGFIsRMQYAPNTQVEILPQGHEsP |
| P40763 | S691 | Sugiyama | STAT3 APRF | VYLYPDIPKEEAFGKyCRPEsQEHPEADPGsAAPyLKTKFI |
| P40763 | S727 | GPS6|EPSD | STAT3 APRF | KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS |
| P40818 | S719 | Sugiyama | USP8 KIAA0055 UBPY | KPQIPAERDREPSKLKRsyssPDItQAIQEEEKRKPTVtPT |
| P40925 | S153 | Sugiyama | MDH1 MDHA | ANtNCLtAsKSAPSIPKENFsCLtRLDHNRAKAQIALKLGV |
| P41091 | T109 | Sugiyama | EIF2S3 EIF2G | YKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLVRH |
| P41252 | S510 | Sugiyama | IARS1 IARS | LSGAKISDLHRESVDHLtIPsRCGKGSLHRISEVFDCWFES |
| P42166 | T160 | Sugiyama | TMPO LAP2 | KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs |
| P42166 | T74 | Sugiyama | TMPO LAP2 | PAGTNsKGPPDFssDEEREPtPVLGsGAAAAGRSRAAVGRK |
| P42167 | T160 | Sugiyama | TMPO LAP2 | KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS |
| P42167 | T74 | Sugiyama | TMPO LAP2 | PAGTNSKGPPDFssDEEREPtPVLGsGAAAAGRSRAAVGRK |
| P42765 | T227 | Sugiyama | ACAA2 | EVKTKKGKQTMQVDEHARPQtTLEQLQKLPPVFKKDGTVTA |
| P43686 | T25 | SIGNOR|EPSD|PSP | PSMC4 MIP224 TBP7 | GILVEKAQDEIPALsVsRPQtGLsFLGPEPEDLEDLYSRYK |
| P46109 | S20 | Sugiyama | CRKL | _MSSARFDssDRsAWyMGPVsRQEAQtRLQGQRHGMFLVRD |
| P46109 | T26 | Sugiyama | CRKL | FDssDRsAWyMGPVsRQEAQtRLQGQRHGMFLVRDsstCPG |
| P46531 | T2511 | PSP | NOTCH1 TAN1 | SSPVDNTPSHQLQVPEHPFLtPsPEsPDQWssssPHSNVSD |
| P46777 | T232 | Sugiyama | RPL5 MSTP030 | MEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAHAAIRENPV |
| P46940 | S727 | Sugiyama | IQGAP1 KIAA0051 | WDEPPNFVQNSMQLSREEIQsSIsGVTAAYNREQLWLANEG |
| P47712 | S724 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | NIDVIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFL |
| P47712 | S727 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP |
| P48506 | S215 | Sugiyama | GCLC GLCL GLCLC | HRRGEKVVINVPIFKDKNtPsPFIETFTEDDEASRASKPDH |
| P48506 | T213 | Sugiyama | GCLC GLCL GLCLC | IRHRRGEKVVINVPIFKDKNtPsPFIETFTEDDEASRASKP |
| P49023 | S85 | Sugiyama | PXN | PLDQWQPSSSRFIHQQPQsssPVyGssAKtssVsNPQDsVG |
| P49327 | S2039 | Sugiyama | FASN FAS | FSSVSCGRGNAGQsNyGFANsAMERICEKRRHEGLPGLAVQ |
| P49327 | S207 | Sugiyama | FASN FAS | GINVLLKPNTSVQFLRLGMLsPEGtCKAFDtAGNGYCRSEG |
| P49327 | S831 | Sugiyama | FASN FAS | NPNALFPPVEFPAPRGtPLIsPLIKWDHSLAWDVPAAEDFP |
| P49327 | T827 | Sugiyama | FASN FAS | GIDANPNALFPPVEFPAPRGtPLIsPLIKWDHSLAWDVPAA |
| P49368 | S243 | Sugiyama | CCT3 CCTG TRIC5 | DVTHPRMRRYIKNPRIVLLDssLEyKKGEsQtDIEITREED |
| P49407 | S412 | Sugiyama | ARRB1 ARR1 | ARQRLKGMKDDKEEEEDGtGsPQLNNR______________ |
| P49407 | T410 | Sugiyama | ARRB1 ARR1 | DFARQRLKGMKDDKEEEEDGtGsPQLNNR____________ |
| P49448 | T410 | Sugiyama | GLUD2 GLUDP1 | KSNAPRVKAKIIAEGANGPttPEADKIFLERNILVIPDLYL |
| P49756 | T187 | Sugiyama | RBM25 RNPC7 | AQLDEWKAKKKASNGNARPEtVTNDDEEALDEETKRRDQMI |
| P49792 | T1144 | Sugiyama | RANBP2 NUP358 | GFRRsDDMFTFHGPGKsVFGtPtLETANKNHEtDGGsAHGD |
| P49903 | T387 | Sugiyama | SEPHS1 SELD SPS SPS1 | IDKPRIIEVAPQVATQNVNPtPGAts_______________ |
| P49959 | T524 | Sugiyama | MRE11 HNGS1 MRE11A | FRETRQKNTNEEDDEVREAMtRARALRsQSEESASAFSADD |
| P50395 | S396 | Sugiyama | GDI2 RABGDIB | IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD |
| P50395 | S45 | Sugiyama | GDI2 RABGDIB | VNGKKVLHMDRNPyyGGEsAsItPLEDLyKRFKIPGsPPEs |
| P50395 | T47 | Sugiyama | GDI2 RABGDIB | GKKVLHMDRNPyyGGEsAsItPLEDLyKRFKIPGsPPEsMG |
| P50895 | S296 | Sugiyama | BCAM LU MSK19 | TPAGWVREGDTVQLLCRGDGsPsPEYTLFRLQDEQEEVLNV |
| P50895 | S298 | Sugiyama | BCAM LU MSK19 | AGWVREGDTVQLLCRGDGsPsPEYTLFRLQDEQEEVLNVNL |
| P50991 | S51 | Sugiyama | CCT4 CCTD SRB | AQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtIt |
| P50991 | T50 | Sugiyama | CCT4 CCTD SRB | PAQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtI |
| P51116 | S603 | Sugiyama | FXR2 FMR1L2 | QRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQsR |
| P51659 | S198 | Sugiyama | HSD17B4 EDH17B4 SDR8C1 | LAIEGRKsNIHCNtIAPNAGsRMTQTVMPEDLVEALKPEYV |
| P51991 | S356 | Sugiyama | HNRNPA3 HNRPA3 | SGQQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsR |
| P51991 | S358 | Sugiyama | HNRNPA3 HNRPA3 | QQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF |
| P51991 | Y360 | Sugiyama | HNRNPA3 HNRPA3 | QSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF__ |
| P51991 | Y364 | Sugiyama | HNRNPA3 HNRPA3 | GPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF______ |
| P52565 | T160 | Sugiyama | ARHGDIA GDIA1 | DKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYsIKSR |
| P52948 | S623 | Sugiyama | NUP98 ADAR2 | KNLNNsNLFsPVNRDsENLAsPsEyPENGERFsFLSKPVDE |
| P53365 | S260 | Sugiyama | ARFIP2 POR1 | TDLEELsLGPRDAGTRGRLEsAQATFQAHRDKYEKLRGDVA |
| P53396 | S656 | Sugiyama | ACLY | IGNTGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISR |
| P54105 | S195 | Sugiyama | CLNS1A CLCI ICLN | SHLTAEGQATLERLEGMLsQsVssQYNMAGVRtEDsIRDyE |
| P54105 | S197 | Sugiyama | CLNS1A CLCI ICLN | LTAEGQATLERLEGMLsQsVssQYNMAGVRtEDsIRDyEDG |
| P54105 | S42 | Sugiyama | CLNS1A CLCI ICLN | DTEAVLNGKGLGtGtLyIAEsRLSWLDGsGLGFSLEYPTIS |
| P54105 | T223 | Sugiyama | CLNS1A CLCI ICLN | AGVRtEDsIRDyEDGMEVDttPtVAGQFEDADVDH______ |
| P54577 | S366 | Sugiyama | YARS1 YARS | KQKPMAKGPAKNsEPEEVIPsRLDIRVGKIITVEKHPDADs |
| P54646 | S176 | Sugiyama | PRKAA2 AMPK AMPK2 | ADFGLSNMMsDGEFLRtsCGsPNyAAPEVISGRLYAGPEVD |
| P54652 | T39 | Sugiyama | HSPA2 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P54750 | S487 | Sugiyama | PDE1A | HIADALRRSNTKGSMsDGsysPDySLAAVDLKSFKNNLVDI |
| P55036 | S242 | Sugiyama | PSMD4 MCB1 | VSMEEQRQRQEEEARRAAAAsAAEAGIATTGtEDsDDALLK |
| P55036 | S266 | Sugiyama | PSMD4 MCB1 | AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ |
| P55072 | S718 | Sugiyama | VCP HEL-220 HEL-S-70 | AIREsIEsEIRRERERQtNPsAMEVEEDDPVPEIRRDHFEE |
| P55795 | S269 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH |
| P55795 | Y266 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst |
| P55809 | S509 | Sugiyama | OXCT1 OXCT SCOT | LWEGLTVDDVQKSTGCDFAVsPKLMPMQQIAN_________ |
| P57740 | S11 | Sugiyama | NUP107 | __________MDRsGFGEIssPVIREAEVTRTARKQSAQKR |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | T214 | Sugiyama | TPI1 TPI | KsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGG |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60709 | S323 | Sugiyama | ACTB | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | T297 | Sugiyama | ACTB | TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI |
| P60842 | S322 | Sugiyama | EIF4A1 DDX2A EIF4A | MHGDMDQKERDVIMREFRsGssRVLITTDLLARGIDVQQVS |
| P60842 | S323 | Sugiyama | EIF4A1 DDX2A EIF4A | HGDMDQKERDVIMREFRsGssRVLITTDLLARGIDVQQVSL |
| P61254 | S32 | Sugiyama | RPL26 | sKNRKRHFNAPsHIRRKIMssPLSKELRQKYNVRSMPIRKD |
| P61313 | S100 | Sugiyama | RPL15 EC45 TCBAP0781 | tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW |
| P61353 | S39 | Sugiyama | RPL27 | SGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVTAAMGK |
| P61353 | S86 | Sugiyama | RPL27 | SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL |
| P61604 | Y88 | Sugiyama | HSPE1 | GDKVLLPEyGGtKVVLDDKDyFLFRDGDILGKyVD______ |
| P61916 | S40 | Sugiyama | NPC2 HE1 | EPVQFKDCGsVDGVIKEVNVsPCPtQPCQLSKGQSYSVNVT |
| P61916 | T44 | Sugiyama | NPC2 HE1 | FKDCGsVDGVIKEVNVsPCPtQPCQLSKGQSYSVNVTFTSN |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61981 | S64 | Sugiyama | YWHAG | LLsVAyKNVVGARRSsWRVIsSIEQKtsADGNEKKIEMVRA |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62263 | S114 | Sugiyama | RPS14 PRO2640 | HIKLRATGGNRtKtPGPGAQsALRALARSGMKIGRIEDVtP |
| P62263 | S69 | Sugiyama | RPS14 PRO2640 | GKETICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELG |
| P62263 | S70 | Sugiyama | RPS14 PRO2640 | KETICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELGI |
| P62263 | T107 | Sugiyama | RPS14 PRO2640 | ELGITALHIKLRATGGNRtKtPGPGAQsALRALARSGMKIG |
| P62263 | T133 | Sugiyama | RPS14 PRO2640 | QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__ |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62273 | Y7 | Sugiyama | RPS29 | ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR |
| P62277 | S14 | Sugiyama | RPS13 | _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK |
| P62304 | S89 | Sugiyama | SNRPE | KSRKQLGRIMLKGDNITLLQsVsN_________________ |
| P62714 | S75 | Sugiyama | PPP2CB | CGDVHGQFHDLMELFRIGGKsPDtNyLFMGDyVDRGYYSVE |
| P62736 | S325 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P62917 | S14 | Sugiyama | RPL8 | _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF |
| P62942 | S9 | Sugiyama | FKBP1A FKBP1 FKBP12 | ____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG |
| P62979 | S115 | Sugiyama | RPS27A UBA80 UBCEP1 | RKKVKLAVLKYYKVDENGKIsRLRRECPsDECGAGVFMAsH |
| P62979 | S123 | Sugiyama | RPS27A UBA80 UBCEP1 | LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63261 | S323 | Sugiyama | ACTG1 ACTG | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | T297 | Sugiyama | ACTG1 ACTG | TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI |
| P63267 | S324 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P67775 | S75 | Sugiyama | PPP2CA | CGDVHGQFHDLMELFRIGGKsPDtNyLFMGDyVDRGYYSVE |
| P67809 | S209 | Sugiyama | YBX1 NSEP1 YB1 | RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ |
| P68032 | S325 | Sugiyama | ACTC1 ACTC | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68133 | S325 | Sugiyama | ACTA1 ACTA | TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68363 | S439 | Sugiyama | TUBA1B | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| P68431 | T46 | Sugiyama | H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J | ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL |
| P78347 | S210 | Sugiyama | GTF2I BAP135 WBSCR6 | EPKKHVGGRVMVtDADRsILsPGGsCGPIKVKTEPTEDSGI |
| P78371 | S144 | Sugiyama | CCT2 99D8.1 CCTB | QTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIAG |
| P78371 | T475 | Sugiyama | CCT2 99D8.1 CCTB | GYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGITE |
| P78417 | S13 | Sugiyama | GSTO1 GSTTLP28 | ________MSGESARsLGKGsAPPGPVPEGsIRIySMRFCP |
| P83731 | S38 | Sugiyama | RPL24 | GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK |
| P84098 | S12 | Sugiyama | RPL19 | _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI |
| P84098 | S37 | Sugiyama | RPL19 | CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV |
| P84243 | T46 | EPSD|Sugiyama | H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B | ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL |
| P85037 | S445 | Sugiyama | FOXK1 MNF | GLMsPRsGGLQtPECLsREGsPIPHDPEFGsKLASVPEYRY |
| P98175 | S89 | Sugiyama | RBM10 DXS8237E GPATC9 GPATCH9 KIAA0122 | sYEAsPGSETQRRRRRRHRHsPtGPPGFPRDGDYRDQDYRT |
| Q00613 | S307 | PSP | HSF1 HSTF1 | RPLSSsPLVRVKEEPPsPPQsPRVEEAsPGRPssVDtLLsP |
| Q00613 | S320 | PSP | HSF1 HSTF1 | EPPsPPQsPRVEEAsPGRPssVDtLLsPtALIDsILREsEP |
| Q00613 | S326 | PSP | HSF1 HSTF1 | QsPRVEEAsPGRPssVDtLLsPtALIDsILREsEPAPAsVT |
| Q00613 | S344 | Sugiyama | HSF1 HSTF1 | LLsPtALIDsILREsEPAPAsVTALtDARGHTDtEGRPPsP |
| Q00613 | S363 | PSP|Sugiyama | HSF1 HSTF1 | AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE |
| Q00613 | S375 | Sugiyama | HSF1 HSTF1 | TDtEGRPPsPPPtstPEKCLsVACLDKNELSDHLDAMDSNL |
| Q00613 | T323 | PSP | HSF1 HSTF1 | sPPQsPRVEEAsPGRPssVDtLLsPtALIDsILREsEPAPA |
| Q00613 | T367 | Sugiyama | HSF1 HSTF1 | ALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNELSDH |
| Q01082 | T2192 | Sugiyama | SPTBN1 SPTB2 | sDRKAKTALPAQsAAtLPARtQEtPsAQMEGFLNRKHEWEA |
| Q01650 | S35 | Sugiyama | SLC7A5 CD98LC LAT1 MPE16 | AAEEKEEAREKMLAAKsADGsAPAGEGEGVtLQRNITLLNG |
| Q01814 | S1160 | Sugiyama | ATP2B2 PMCA2 | QIRVVKAFRssLyEGLEKPEsRtsIHNFMAHPEFRIEDSQP |
| Q01844 | S273 | Sugiyama | EWSR1 EWS | QYSQQSSSYGQQSsFRQDHPssMGVyGQESGGFSGPGENRS |
| Q02543 | S123 | Sugiyama | RPL18A | AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK |
| Q02543 | T102 | Sugiyama | RPL18A | LRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAH |
| Q02543 | T107 | Sugiyama | RPL18A | RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM |
| Q02543 | T24 | Sugiyama | RPL18A | SGTLREYKVVGRCLPTPKCHtPPLYRMRIFAPNHVVAKSRF |
| Q02543 | Y110 | Sugiyama | RPL18A | tHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIMKVE |
| Q02543 | Y97 | Sugiyama | RPL18A | NFGIWLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARH |
| Q02790 | S15 | Sugiyama | FKBP4 FKBP52 | ______MTAEEMKAtEsGAQsAPLPMEGVDIsPKQDEGVLK |
| Q02790 | T9 | Sugiyama | FKBP4 FKBP52 | ____________MTAEEMKAtEsGAQsAPLPMEGVDIsPKQ |
| Q04637 | S1041 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | QQLMAKGsDKRRGGPPGPPIsRGLPLVDDGGWNtVPIsKGS |
| Q04637 | S1231 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | tEDRDRGRDAVKREAALPPVsPLKAALsEEELEKKsKAIIE |
| Q04917 | S25 | Sugiyama | YWHAH YWHA1 | EQLLQRARLAEQAERyDDMAsAMKAVtELNEPLsNEDRNLL |
| Q04917 | S64 | Sugiyama | YWHAH YWHA1 | LLsVAyKNVVGARRSsWRVIsSIEQKTMADGNEKKLEKVKA |
| Q06210 | S205 | Sugiyama | GFPT1 GFAT GFPT | FALVFKSVHFPGQAVGTRRGsPLLIGVRSEHKLSTDHIPIL |
| Q07020 | T136 | Sugiyama | RPL18 | AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP |
| Q07021 | S213 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | VGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDSLDW |
| Q07021 | T165 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD |
| Q07960 | S49 | Sugiyama | ARHGAP1 CDC42GAP RHOGAP1 | DEKNWPsDEMPDFPKsDDsKsssPELVtHLKWDDPyyDIAR |
| Q07960 | S50 | Sugiyama | ARHGAP1 CDC42GAP RHOGAP1 | EKNWPsDEMPDFPKsDDsKsssPELVtHLKWDDPyyDIARH |
| Q08J23 | S743 | Sugiyama | NSUN2 SAKI TRM4 | AstGQPDNDVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGV |
| Q08J23 | S751 | Sugiyama | NSUN2 SAKI TRM4 | DVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGVHPPR____ |
| Q08J23 | T755 | Sugiyama | NSUN2 SAKI TRM4 | GQRAGEPNsPDAEEANsPDVtAGCDPAGVHPPR________ |
| Q09666 | S230 | Sugiyama | AHNAK PM227 | sGsGAAsPtGsAVDIRAGAIsAsGPELQGAGHsKLQVTMPG |
| Q09666 | S41 | Sugiyama | AHNAK PM227 | HGLTIAQRDDGVFVQEVtQNsPAARTGVVKEGDQIVGATIy |
| Q10570 | S712 | Sugiyama | CPSF1 CPSF160 | QSKVITLCLYRDLSGMFTTEsRLGGARDELGGRSGPEAEGL |
| Q12765 | T295 | Sugiyama | SCRN1 KIAA0193 | TASGVSVLPQNRSSPCIHyFtGtPDPSRSIFKPFIFVDDVK |
| Q12765 | T320 | Sugiyama | SCRN1 KIAA0193 | PSRSIFKPFIFVDDVKLVPKtQsPCFGDDDPAKKEPRFQEK |
| Q12792 | S143 | Sugiyama | TWF1 PTK9 | GTVKEDVSLHGYKKyLLsQssPAPLtAAEEELRQIKINEVQ |
| Q12965 | S1009 | Sugiyama | MYO1E MYO1C | yTsMARPPLPRQQstssDRVsQtPEsLDFLKVPDQGAAGVR |
| Q12965 | T1011 | Sugiyama | MYO1E MYO1C | sMARPPLPRQQstssDRVsQtPEsLDFLKVPDQGAAGVRRQ |
| Q13085 | S104 | Sugiyama | ACACA ACAC ACC1 ACCA | LVKQGRDRKKIDSQRDFTVAsPAEFVTRFGGNKVIEKVLIA |
| Q13098 | S485 | Sugiyama | GPS1 COPS1 CSN1 | HVKsPPREGsQGELtPANsQsRMstNM______________ |
| Q13131 | S187 | Sugiyama | PRKAA1 AMPK1 | ADFGLsNMMsDGEFLRtsCGsPNyAAPEVISGRLYAGPEVD |
| Q13136 | S666 | Sugiyama | PPFIA1 LIP1 | IQEEKENTEQRAEEIESRVGsGsLDNLGRFRSMssIPPYPA |
| Q13177 | T154 | Sugiyama | PAK2 | tVKQKyLsFtPPEKDGFPsGtPALNAKGtEAPAVVtEEEDD |
| Q13263 | S417 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | AWTKSAEAFGKIVAERPGtNstGPAPMAPPRAPGPLSKQGs |
| Q13263 | T415 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | LNAWTKSAEAFGKIVAERPGtNstGPAPMAPPRAPGPLSKQ |
| Q13283 | S231 | Sugiyama | G3BP1 G3BP | QEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsW |
| Q13283 | S232 | Sugiyama | G3BP1 G3BP | EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA |
| Q13283 | S250 | Sugiyama | G3BP1 G3BP | sssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGI |
| Q13283 | S256 | Sugiyama | G3BP1 G3BP | ADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPHVVK |
| Q13283 | T241 | Sugiyama | G3BP1 G3BP | ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP |
| Q13283 | T255 | Sugiyama | G3BP1 G3BP | PADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPHVV |
| Q13409 | S97 | Sugiyama | DYNC1I2 DNCI2 DNCIC2 | FSEYWVPPPMsPSSKsVStPsEAGsQDsGDGAVGsRTLHWD |
| Q13442 | Y17 | Sugiyama | PDAP1 HASPP28 | ____MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREE |
| Q13509 | S115 | Sugiyama | TUBB3 TUBB4 | SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL |
| Q13509 | S168 | Sugiyama | TUBB3 TUBB4 | GTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS |
| Q13509 | S172 | Sugiyama | TUBB3 TUBB4 | ISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSIHQL |
| Q13541 | S101 | EPSD|PSP | EIF4EBP1 | VtsPssDEPPMEAsQsHLRNsPEDKRAGGEEsQFEMDI___ |
| Q13541 | S65 | EPSD|PSP | EIF4EBP1 | ttPGGtRIIyDRKFLMECRNsPVtKtPPRDLPtIPGVtsPs |
| Q13573 | S224 | Sugiyama | SNW1 SKIIP SKIP | KDPMEPPRFKINKKIPRGPPsPPAPVMHsPsRKMTVKEQQE |
| Q13573 | S234 | Sugiyama | SNW1 SKIIP SKIP | INKKIPRGPPsPPAPVMHsPsRKMTVKEQQEWKIPPCISNW |
| Q13586 | S620 | Sugiyama | STIM1 GOK | sPsAPPGGsPHLDssRsHsPssPDPDtPsPVGDSRALQASR |
| Q13596 | S368 | Sugiyama | SNX1 | AKSLAMLGSSEDNTALSRALsQLAEVEEKIEQLHQEQANND |
| Q13884 | S87 | Sugiyama | SNTB1 SNT2B1 | SFCRGAGAGHPGAGGAQPPDsPAGVRTAFTDLPEQVPESIS |
| Q13885 | S115 | Sugiyama | TUBB2A TUBB2 | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q14151 | S818 | Sugiyama | SAFB2 KIAA0138 | QHYGDDRHGHGGPPERHGRDsRDGWGGyGsDKRLsEGRGLP |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14157 | S477 | Sugiyama | UBAP2L KIAA0144 NICE4 | PsKstsAPQMsPGssDNQsssPQPAQQKLKQQKKKAsLTSK |
| Q14160 | S1232 | Sugiyama | SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL | AAGIGHRNsLEsIssIDRELsPEGPGKEKELPGQTLHWGPE |
| Q14160 | S1486 | Sugiyama | SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL | RHQERLRVQsPEPPAPERALsPAELRALEAEKRALWRAARM |
| Q14160 | S504 | Sugiyama | SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL | MKRSIEGRRsEACPCQPDsGsPLPAEEEKRLsAESGLSEDS |
| Q14181 | T127 | Sugiyama | POLA2 | EILLNSYttPSKGSQKRAIstPEtPLtKRsVstRsPHQLLs |
| Q14181 | T130 | Sugiyama | POLA2 | LNSYttPSKGSQKRAIstPEtPLtKRsVstRsPHQLLsPss |
| Q14194 | S522 | EPSD|PSP | CRMP1 DPYSL1 ULIP3 | PVyEVPAtPKYAtPAPsAKssPsKHQPPPIRNLHQSNFsLs |
| Q14195 | S518 | SIGNOR | DPYSL3 CRMP4 DRP3 ULIP ULIP1 | MYDGPVFDLtttPKGGtPAGsARGsPTRPNPPVRNLHQSGF |
| Q14195 | S522 | GPS6|EPSD|PSP | DPYSL3 CRMP4 DRP3 ULIP ULIP1 | PVFDLtttPKGGtPAGsARGsPTRPNPPVRNLHQSGFSLSG |
| Q14195 | T509 | SIGNOR | DPYSL3 CRMP4 DRP3 ULIP ULIP1 | ADLHAVPRGMYDGPVFDLtttPKGGtPAGsARGsPTRPNPP |
| Q14195 | T514 | SIGNOR | DPYSL3 CRMP4 DRP3 ULIP ULIP1 | VPRGMYDGPVFDLtttPKGGtPAGsARGsPTRPNPPVRNLH |
| Q14203 | S31 | Sugiyama | DCTN1 | RTPSGSRMsAEASARPLRVGsRVEVIGKGHRGTVAYVGATL |
| Q14204 | S2410 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | GEDEAQRRRKGKEDEGEEAAsPMLQIQRDAATIMQPYFTSN |
| Q14240 | S323 | Sugiyama | EIF4A2 DDX2B EIF4F | LHGDMDQKERDVIMREFRsGssRVLITTDLLARGIDVQQVS |
| Q14240 | S324 | Sugiyama | EIF4A2 DDX2B EIF4F | HGDMDQKERDVIMREFRsGssRVLITTDLLARGIDVQQVSL |
| Q14247 | S405 | Sugiyama | CTTN EMS1 | EEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVyEDAA |
| Q14247 | T399 | Sugiyama | CTTN EMS1 | KERQEQEEARRKLEEQARAKtQtPPVsPAPQPtEERLPssP |
| Q14247 | T401 | Sugiyama | CTTN EMS1 | RQEQEEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVy |
| Q14258 | S100 | Sugiyama | TRIM25 EFP RNF147 ZNF147 | DLAREPPADVWtPPARAsAPsPNAQVACDHCLKEAAVKTCL |
| Q14498 | S334 | Sugiyama | RBM39 HCC1 RNPC2 | FELAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtT |
| Q14498 | S336 | Sugiyama | RBM39 HCC1 RNPC2 | LAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGR |
| Q14566 | T266 | Sugiyama | MCM6 | GTLIVVPDVSKLSTPGARAEtNsRVsGVDGyEtEGIRGLRA |
| Q14568 | S165 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14694 | S370 | Sugiyama | USP10 KIAA0190 | KPssssPVAYVEtKysPPAIsPLVSEKQVEVKEGLVPVSED |
| Q14847 | T104 | Sugiyama | LASP1 MLN50 | VRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsNIKyHE |
| Q14974 | S12 | Sugiyama | KPNB1 NTF97 | _________MELITILEKtVsPDRLELEAAQKFLERAAVEN |
| Q14980 | S1317 | Sugiyama | NUMA1 NMP22 NUMA | LREEAEKQRVASENLRQELTsQAERAEELGQELKAWQEKFF |
| Q14980 | S1757 | Sugiyama | NUMA1 NMP22 NUMA | ITSKLPRtQPDGtsVPGEPAsPIsQRLPPKVEsLEsLyFtP |
| Q14C86 | S740 | Sugiyama | GAPVD1 GAPEX5 KIAA1521 RAP6 | LPSDSEAPDLKQEERLQELEsCsGLGstSDDTDVREVSSRP |
| Q15003 | S81 | Sugiyama | NCAPH BRRN BRRN1 CAPH KIAA0074 | EKERLQRRRsRVFDLQFstDsPRLLAsPsSRsIDIsATIPK |
| Q15008 | S361 | Sugiyama | PSMD6 KIAA0107 PFAAP4 | GRLHCKIDKVNEIVETNRPDsKNWQyQETIKKGDLLLNRVQ |
| Q15021 | T1339 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | PSTGSRyQPLAstAsDNDFVtPEPRRTTRRHPNTQQRASKK |
| Q15084 | S248 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | LAsRYGIRGFPtIKIFQKGEsPVDyDGGRTRsDIVsRALDL |
| Q15293 | T76 | Sugiyama | RCN1 RCN | FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD |
| Q15388 | S135 | Sugiyama | TOMM20 KIAA0016 | PPPVFQMLLTKLPTISQRIVsAQsLAEDDVE__________ |
| Q15424 | S794 | Sugiyama | SAFB HAP HET SAFB1 | EREGQHYPERHGGPERHGRDsRDGWGGyGsDKRMsEGRGLP |
| Q15642 | S296 | Sugiyama | TRIP10 CIP4 STOT STP | FARPGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRS |
| Q15642 | S298 | Sugiyama | TRIP10 CIP4 STOT STP | RPGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRT |
| Q15642 | S495 | Sugiyama | TRIP10 CIP4 STOT STP | VLsNRGDsLSRHARPPDPPAsAPPDsssNsAsQDtKESSEE |
| Q15717 | S41 | Sugiyama | ELAVL1 HUR | NLIVNYLPQNMTQDELRSLFssIGEVESAKLIRDKVAGHSL |
| Q15738 | S106 | Sugiyama | NSDHL H105E3 | CSRQDLyPALKGVNTVFHCAsPPPSSNNKELFYRVNYIGTK |
| Q15750 | S378 | Sugiyama | TAB1 MAP3K7IP1 | MTLLVRNFGYPLGEMSQPtPsPAPAAGGRVYPVSVPYSSAQ |
| Q15750 | T376 | Sugiyama | TAB1 MAP3K7IP1 | EDMTLLVRNFGYPLGEMSQPtPsPAPAAGGRVYPVSVPYSS |
| Q15758 | S493 | Sugiyama | SLC1A5 ASCT2 M7V1 RDR RDRC | EGDALGAGLLQNYVDRtEsRstEPELIQVKsELPLDPLPVP |
| Q15814 | S330 | Sugiyama | TBCC | RSKNNWNDVDDFNWLARDMAsPNWsILPEEERNIQWD____ |
| Q16513 | S583 | Sugiyama | PKN2 PRK2 PRKCL2 | VTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQDs |
| Q16514 | S51 | Sugiyama | TAF12 TAF15 TAF2J TAFII20 | MANSTAVVKIPGtPGAGGRLsPENNQVLTKKKLQDLVREVD |
| Q16514 | T43 | Sugiyama | TAF12 TAF15 TAF2J TAFII20 | AStPPQGSMANSTAVVKIPGtPGAGGRLsPENNQVLTKKKL |
| Q16555 | S522 | EPSD|PSP | DPYSL2 CRMP2 ULIP2 | PVCEVsVtPKtVtPAssAKtsPAKQQAPPVRNLHQsGFsLs |
| Q16630 | T157 | Sugiyama | CPSF6 CFIM68 | SKKLMDLLPKRELHGQNPVVtPCNKQFLsQFEMQSRKTTQS |
| Q16695 | T46 | Sugiyama | H3-4 H3FT HIST3H3 | ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL |
| Q16740 | S222 | Sugiyama | CLPP | KKQLYNIyAKHTKQSLQVIEsAMERDRYMSPMEAQEFGILD |
| Q32MZ4 | S16 | Sugiyama | LRRFIP1 GCF2 TRIP | _____MtsPAAAQSREIDCLsPEAQKLAEARLAAKRAARAE |
| Q32MZ4 | S733 | Sugiyama | LRRFIP1 GCF2 TRIP | ssPAEPKsEDADRCtLPEHEsPsQDIsDACEAEsTERCEMS |
| Q53EZ4 | S425 | Sugiyama | CEP55 C10orf3 URCC6 | ITEPLVTFQGETENREKVAAsPKsPtAALNEsLVECPKCNI |
| Q53EZ4 | T430 | Sugiyama | CEP55 C10orf3 URCC6 | VTFQGETENREKVAAsPKsPtAALNEsLVECPKCNIQYPAT |
| Q5H9R7 | S502 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | QQLIKDLPDEVRERWETFCTsSLGEtNKRNTVDLVttCHIH |
| Q5H9R7 | S852 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | DAEECPETAEAKCAAPRPPsssPEQRTGQPSAPGDtsVNGP |
| Q5JSH3 | S50 | Sugiyama | WDR44 RPH11 | KVGLSTFKETENTAYKVGNEsPVQELKQDVSKKIIEsIIEE |
| Q5JSH3 | S561 | Sugiyama | WDR44 RPH11 | KNAFDYFNNMRMKYNtEGRVsPsPsQEsLsssKsDTDtGVC |
| Q5R3I4 | S362 | Sugiyama | TTC38 | GAHDPQTTQELLTTLRDASEsPGENCQHLLARDVGLPLCQA |
| Q5SRE5 | S1523 | Sugiyama | NUP188 KIAA0169 | QNKNGDGLPSAVAQRVQRPPsAASAAPsssKQPAADTEASE |
| Q5SW79 | T1533 | Sugiyama | CEP170 FAM68A KAB KIAA0470 | LPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAVSAAA |
| Q5T4S7 | S178 | Sugiyama | UBR4 KIAA0462 KIAA1307 RBAF600 | AKLPQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLT |
| Q5T4S7 | S181 | Sugiyama | UBR4 KIAA0462 KIAA1307 RBAF600 | PQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLTSVF |
| Q5VT52 | S1070 | Sugiyama | RPRD2 KIAA0460 HSPC099 | TATDQQQQEEHYRIETRVsssCLDLPDSTEEKGAPIETLGy |
| Q6FI81 | S272 | Sugiyama | CIAPIN1 CUA001 PRO0915 | GLAEELEKEKSREQMSSQPKsACGNCyLGDAFRCAsCPyLG |
| Q6L8Q7 | S266 | Sugiyama | PDE12 | LKLHCTPGDGQRFGHSRELEsVCVVEAGPGTCTFDHRHLYT |
| Q6NVY1 | S242 | Sugiyama | HIBCH | LAMLEEDLLALKsPSKENIAsVLENyHtESKIDRDKSFILE |
| Q6NW29 | S28 | Sugiyama | RWDD4 FAM28A RWDD4A | EMELEALRSIyEGDEsFRELsPVSFQyRIGENGDPKAFLIE |
| Q6NXT2 | T45 | Sugiyama | H3-5 H3F3C | AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL |
| Q6P1N0 | S208 | Sugiyama | CC2D1A AKI1 LGD2 | EADIPPPVAIGKGPAstPtysPAPTQPAPRIASAPEPRVTL |
| Q6P1N0 | T204 | Sugiyama | CC2D1A AKI1 LGD2 | NAIDEADIPPPVAIGKGPAstPtysPAPTQPAPRIASAPEP |
| Q6P996 | T691 | Sugiyama | PDXDC1 KIAA0251 | ESTEPIyVYKAQGAGVtLPPtPsGsRtKQRLPGQKPFKRsL |
| Q6P996 | T697 | Sugiyama | PDXDC1 KIAA0251 | yVYKAQGAGVtLPPtPsGsRtKQRLPGQKPFKRsLRGsDAL |
| Q6PKG0 | S521 | Sugiyama | LARP1 KIAA0731 LARP | NCPEFVPRQHYQKEtEsAPGsPRAVtPVPtKTEEVSNLKTL |
| Q6PKG0 | S774 | Sugiyama | LARP1 KIAA0731 LARP | LFGAPEPstIARsLPttVPEsPNyRNtRtPRtPRtPQLKDS |
| Q6PKG0 | T526 | Sugiyama | LARP1 KIAA0731 LARP | VPRQHYQKEtEsAPGsPRAVtPVPtKTEEVSNLKTLPKGLs |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q71DI3 | T46 | Sugiyama | H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D | ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL |
| Q71RC2 | S594 | Sugiyama | LARP4 PP13296 | GLNQttIPVsPPsttKPsRAstAsPCNNNINAAtAVALQEP |
| Q71RC2 | S597 | Sugiyama | LARP4 PP13296 | QttIPVsPPsttKPsRAstAsPCNNNINAAtAVALQEPRKL |
| Q71U36 | S439 | Sugiyama | TUBA1A TUBA3 | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| Q7KZ85 | T1532 | Sugiyama | SUPT6H KIAA0162 SPT6H | KDHYQDPVPGItPssssRtRtPAsINAtPANINLADLTRAV |
| Q7KZ85 | T1539 | Sugiyama | SUPT6H KIAA0162 SPT6H | VPGItPssssRtRtPAsINAtPANINLADLTRAVNALPQNM |
| Q7KZF4 | S720 | Sugiyama | SND1 TDRD11 | DVETGTQLEKLMENMRNDIAsHPPVEGsyAPRRGEFCIAKF |
| Q7Z2W4 | T273 | Sugiyama | ZC3HAV1 ZC3HDC2 PRO1677 | FFQGsQEFLASASAsAERsCtPsPDQIsHRAsLEDAPVDDL |
| Q7Z417 | S692 | Sugiyama | NUFIP2 KIAA1321 PIG1 | IWNLQKQDPKRIItyNEAMDsPDQ_________________ |
| Q7Z460 | S256 | Sugiyama | CLASP1 KIAA0622 MAST1 | ANDKNFDDEDsVDGNRPssAsStSSKAPPSSRRNVGMGTTR |
| Q7Z460 | T258 | Sugiyama | CLASP1 KIAA0622 MAST1 | DKNFDDEDsVDGNRPssAsStSSKAPPSSRRNVGMGTTRRL |
| Q7Z4H7 | S552 | Sugiyama | HAUS6 DGT6 FAM29A KIAA1574 | PFQKEQDHLVEEVARAVLsDsPQLsEGKEIKLEELIDsLGS |
| Q7Z4V5 | S652 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | GssEDLHDsVREGPDLDRPGsDRQERERARGDsEALDEEs_ |
| Q7Z5L9 | S360 | Sugiyama | IRF2BP2 | EANGANGSKAVARTARKRKPsPEPEGEVGPPKINGEAQPWL |
| Q7Z6Z7 | S2887 | Sugiyama | HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272 | LEEAVGDTSAAGSSEQPRAGsstPGDAPPAVAEVQGRSDGs |
| Q7Z6Z7 | T2889 | Sugiyama | HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272 | EAVGDTSAAGSSEQPRAGsstPGDAPPAVAEVQGRSDGsGE |
| Q86UE4 | S146 | Sugiyama | MTDH AEG1 LYRIC | PKPNGRTVEVAEGEAVRtPQsVtAKQPPEIDKKNEKSKKNK |
| Q86UE4 | T143 | Sugiyama | MTDH AEG1 LYRIC | SEKPKPNGRTVEVAEGEAVRtPQsVtAKQPPEIDKKNEKSK |
| Q86UF2 | S140 | Sugiyama | CTAGE6 CTAGE6P | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q86UU1 | S665 | Sugiyama | PHLDB1 KIAA0638 LL5A DLNB07 | ALALAGRRPsRGLAGASGRssEEPGVATQRLWEsMERsDEE |
| Q86VP6 | S376 | Sugiyama | CAND1 KIAA0829 TIP120 TIP120A | CLDAVVSTRHEMLPEFyKTVsPALISRFKEREENVKADVFH |
| Q86W92 | S1001 | Sugiyama | PPFIBP1 KIAA1230 | NLTHMLKEDDMFKDFAARsPsAsItDEDsNV__________ |
| Q86W92 | S1003 | Sugiyama | PPFIBP1 KIAA1230 | THMLKEDDMFKDFAARsPsAsItDEDsNV____________ |
| Q86W92 | S999 | Sugiyama | PPFIBP1 KIAA1230 | INNLTHMLKEDDMFKDFAARsPsAsItDEDsNV________ |
| Q86WR0 | S187 | Sugiyama | CCDC25 | KKREKEEMKKKREMDELRSYssLMKVENMSSNQDGNDsDEF |
| Q86X29 | S365 | Sugiyama | LSR ILDR3 LISCH | MGPAYNGYPGGYPGDVDRsssAGGQGsyVPLLRDTDssVAs |
| Q86YP4 | S100 | Sugiyama | GATAD2A | DGPVDMRTSHSDMKSERRPPsPDVIVLsDNEQPssPRVNGL |
| Q8IWS0 | S346 | Sugiyama | PHF6 CENP-31 KIAA1823 | CKNHSGNDERDEEDEERESKsRGKVEIDQQQLtQQQLNGN_ |
| Q8IWW6 | S240 | Sugiyama | ARHGAP12 | SSSsTEQIRAttPPNQGRPDsPVyANLQELKISQSALPPLP |
| Q8IWW6 | T231 | Sugiyama | ARHGAP12 | QDSEsGDELSSSsTEQIRAttPPNQGRPDsPVyANLQELKI |
| Q8IX94 | S140 | Sugiyama | CTAGE4 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q8IY95 | S229 | Sugiyama | TMEM192 | EEKIyAyPSNITSETGFRTIssLEEIVEKQGDTIEYLKRHN |
| Q8N201 | S495 | Sugiyama | INTS1 KIAA1440 UNQ1821/PRO3434 | KFLAMVFQDLLTNKDDYLRAsRALLREIIKQTKHEINFQAF |
| Q8N3D4 | S1164 | Sugiyama | EHBP1L1 | QELQLVQLEGGGGAGTYRVGsAQPsPPDDLDAGGLAQRLRG |
| Q8N684 | T203 | Sugiyama | CPSF7 | GGIPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLP |
| Q8N6T3 | S343 | Sugiyama | ARFGAP1 ARF1GAP | NIDQSFWETFGSAEPTKtRKsPssDsWtCADtstERRssDs |
| Q8N6T3 | S346 | Sugiyama | ARFGAP1 ARF1GAP | QSFWETFGSAEPTKtRKsPssDsWtCADtstERRssDsWEV |
| Q8N7H5 | S505 | Sugiyama | PAF1 PD2 | GSNGGGQRSRSHSRSASPFPsGSEHSAQEDGSEAAASDSSE |
| Q8NBJ5 | S612 | Sugiyama | COLGALT1 GLT25D1 PSEC0241 | QKMREQQALSREAKNsDVLQsPLDsAARDEL__________ |
| Q8NBJ5 | S616 | Sugiyama | COLGALT1 GLT25D1 PSEC0241 | EQQALSREAKNsDVLQsPLDsAARDEL______________ |
| Q8NBJ7 | S281 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | ADGsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPPGEL |
| Q8NBJ7 | S44 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | NGQATSMVQLQGGRFLMGtNsPDSRDGDGPVREATVKPFAI |
| Q8NBJ7 | T272 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | LRGAsWIDtADGsANHRARVttRMGNtPDsAsDNLGFRCAA |
| Q8NBJ7 | T273 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | RGAsWIDtADGsANHRARVttRMGNtPDsAsDNLGFRCAAD |
| Q8NBJ7 | T278 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | IDtADGsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPP |
| Q8NBS9 | S292 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | KKVDQYKGKRDLEsLREyVEsQLQRTETGATETVTPSEAPV |
| Q8NBS9 | S426 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | KKVSEHSGGRDLDSLHRFVLsQAKDEL______________ |
| Q8NE71 | S293 | Sugiyama | ABCF1 ABC50 | SLKAANAAENDFsVsQAEMSsRQAMLENASDIKLEKFSISA |
| Q8TAD8 | S35 | Sugiyama | SNIP1 | RHRDGDVVLPAGVVVKQERLsPEVAPPAHRRPDHsGGsPsP |
| Q8TC07 | S675 | Sugiyama | TBC1D15 | TSAFQSNALPTLSASGARNDsPtQIPVssDVCRLtPA____ |
| Q8TC07 | T689 | Sugiyama | TBC1D15 | SGARNDsPtQIPVssDVCRLtPA__________________ |
| Q8TCS8 | S754 | Sugiyama | PNPT1 PNPASE | KYFGRDPADGRMRLSRKVLQsPAtTVVRTLNDRssIVMGEP |
| Q8TD19 | S13 | Sugiyama | NEK9 KIAA1995 NEK8 NERCC | ________MsVLGEYERHCDsINSDFGSEsGGCGDssPGPS |
| Q8TD19 | S22 | Sugiyama | NEK9 KIAA1995 NEK8 NERCC | sVLGEYERHCDsINSDFGSEsGGCGDssPGPSASQGPRAGG |
| Q8TD19 | S28 | Sugiyama | NEK9 KIAA1995 NEK8 NERCC | ERHCDsINSDFGSEsGGCGDssPGPSASQGPRAGGGAAEQE |
| Q8TD19 | S29 | Sugiyama | NEK9 KIAA1995 NEK8 NERCC | RHCDsINSDFGSEsGGCGDssPGPSASQGPRAGGGAAEQEE |
| Q8TDD1 | S624 | Sugiyama | DDX54 | FQQGQQGRQEQQEGPVGPAPsRPALQEKQPEKEEEEEAGEs |
| Q8TEW0 | S383 | Sugiyama | PARD3 PAR3 PAR3A | KEQYEQLSQSEKNNyyssRFsPDsQyIDNRSVNSAGLHTVQ |
| Q8TEW0 | S728 | Sugiyama | PARD3 PAR3 PAR3A | DDRERRIsHsLysGIEGLDEsPsRNAALsRIMGESGKYQLS |
| Q8TEW0 | S730 | Sugiyama | PARD3 PAR3 PAR3A | RERRIsHsLysGIEGLDEsPsRNAALsRIMGESGKYQLSPT |
| Q8TEW0 | S736 | Sugiyama | PARD3 PAR3 PAR3A | HsLysGIEGLDEsPsRNAALsRIMGESGKYQLSPTVNMPQD |
| Q8WVV9 | S75 | Sugiyama | HNRNPLL HNRPLL SRRF BLOCK24 | GGGRsFsQPEAGGsHHKVsVsPVVHVRGLCEsVVEADLVEA |
| Q8WWM7 | S111 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | PGAAAIGsARGQstGKGPPQsPVFEGVyNNSRMLHFLTAVV |
| Q8WWM7 | S559 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | RFQLEELRKFGAQFKLQPsssPENsLDPFPPRILKEEPKGK |
| Q8WZA9 | S44 | Sugiyama | IRGQ IRGQ1 FKSG27 | IAALCDKDVEtLEAPEGRPDsGVPSLRAAGPGLFLGELSCP |
| Q92499 | S481 | Sugiyama | DDX1 | KSHIRTDDVHAKDNTRPGANsPEMWSEAIKILKGEYAVRAI |
| Q92539 | T289 | Sugiyama | LPIN2 KIAA0249 | FPESTKVSKRERSDHHPRTAtItPSENTHFRVIPsEDNLIS |
| Q92539 | T291 | Sugiyama | LPIN2 KIAA0249 | ESTKVSKRERSDHHPRTAtItPSENTHFRVIPsEDNLISEV |
| Q92597 | T366 | Sugiyama | NDRG1 CAP43 DRG1 RTP | tSEGTRsRsHtsEGtRsRsHtsEGAHLDItPNsGAAGNsAG |
| Q92630 | S471 | Sugiyama | DYRK2 | RAKNFVSSKGYPRYCTVttLsDGsVVLNGGRsRRGKLRGPP |
| Q92630 | S474 | Sugiyama | DYRK2 | NFVSSKGYPRYCTVttLsDGsVVLNGGRsRRGKLRGPPESR |
| Q92630 | S482 | Sugiyama | DYRK2 | PRYCTVttLsDGsVVLNGGRsRRGKLRGPPESREWGNALKG |
| Q92630 | S556 | Sugiyama | DYRK2 | RRRLPKPPTGEKTSVKRITEsTGAItSISKLPPPSSSASKL |
| Q92630 | T468 | Sugiyama | DYRK2 | AsKRAKNFVSSKGYPRYCTVttLsDGsVVLNGGRsRRGKLR |
| Q92630 | T469 | Sugiyama | DYRK2 | sKRAKNFVSSKGYPRYCTVttLsDGsVVLNGGRsRRGKLRG |
| Q92630 | T561 | Sugiyama | DYRK2 | KPPTGEKTSVKRITEsTGAItSISKLPPPSSSASKLRtNLA |
| Q92630 | T578 | Sugiyama | DYRK2 | GAItSISKLPPPSSSASKLRtNLAQMtDANGNIQQRTVLPK |
| Q92630 | T584 | Sugiyama | DYRK2 | SKLPPPSSSASKLRtNLAQMtDANGNIQQRTVLPKLVS___ |
| Q92630 | Y382 | Sugiyama | DYRK2 | SGIKVIDFGSSCYEHQRVYtyIQSRFYRAPEVILGARYGMP |
| Q92734 | S183 | Sugiyama | TFG | AsMsAFDPLKNQDEINKNVMsAFGLtDDQVsGPPsAPAEDR |
| Q92734 | S197 | Sugiyama | TFG | INKNVMsAFGLtDDQVsGPPsAPAEDRSGTPDSIASSSSAA |
| Q92785 | S151 | Sugiyama | DPF2 BAF45D REQ UBID4 | RGAPDPRVDDDsLGEFPVTNsRARKRILEPDDFLDDLDDED |
| Q92878 | S1305 | Sugiyama | RAD50 | KFYRIKKNIDQCSEIVKCSVsSLGFNVH_____________ |
| Q92890 | S245 | Sugiyama | UFD1 UFD1L | FRAFsGsGNRLDGKKKGVEPsPsPIKPGDIKRGIPNyEFKL |
| Q92890 | S247 | Sugiyama | UFD1 UFD1L | AFsGsGNRLDGKKKGVEPsPsPIKPGDIKRGIPNyEFKLGK |
| Q969G3 | S316 | Sugiyama | SMARCE1 BAF57 | ARKRQEEREKEAAEQAERsQssIVPEEEQAANKGEEKKDDE |
| Q969G3 | S317 | Sugiyama | SMARCE1 BAF57 | RKRQEEREKEAAEQAERsQssIVPEEEQAANKGEEKKDDEN |
| Q96B36 | S212 | Sugiyama | AKT1S1 PRAS40 | GFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAED |
| Q96C19 | S74 | Sugiyama | EFHD2 SWS1 | ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI |
| Q96C19 | S76 | Sugiyama | EFHD2 SWS1 | SAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQIKD |
| Q96CV9 | T525 | Sugiyama | OPTN FIP2 GLC1E HIP7 HYPL NRP | AFEDGGRQsLMEMQsRHGARtsDsDQQAyLVQRGAEDRDWR |
| Q96D46 | S462 | Sugiyama | NMD3 CGI-07 | FLEDLEEDEAIRKNVNIyRDsAIPVEsDtDDEGAPRISLAE |
| Q96EK9 | S184 | Sugiyama | KTI12 SBBI81 | GSAQADVPKELEREEsGAAEsPALVtPDSEKSAKHGsGAFy |
| Q96EN8 | S530 | Sugiyama | MOCOS | APSADSQADVIPAVMGRRsLsPQEDALTGSRVWNNSSTVNA |
| Q96GM8 | S420 | Sugiyama | TOE1 | KNDLEMGIKAARPEIADRATsEVPGsQAsPNPVPGDGLHRA |
| Q96GM8 | S428 | Sugiyama | TOE1 | KAARPEIADRATsEVPGsQAsPNPVPGDGLHRAGFDAFMTG |
| Q96JC9 | S165 | Sugiyama | EAF1 | FRAPTKPPVGPKtsPLKDNPsPEPQLDDIKRELRAEVDIIE |
| Q96L14 | T242 | Sugiyama | CEP170P1 CEP170L KIAA0470L | LPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAVSAAA |
| Q96MH2 | S76 | Sugiyama | HEXIM2 L3 | EDLAGAVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPS |
| Q96QK1 | S783 | Sugiyama | VPS35 MEM3 TCCCTA00141 | tEQINKHFHNtLEHLRLRREsPEsEGPIyEGLIL_______ |
| Q96QR8 | S23 | Sugiyama | PURB | DGDsGsERGGGGGPCGFQPAsRGGGEQEtQELASKRLDIQN |
| Q96QR8 | T31 | Sugiyama | PURB | GGGGGPCGFQPAsRGGGEQEtQELASKRLDIQNKRFyLDVK |
| Q96S44 | T8 | Sugiyama | TP53RK C20orf64 PRPK | _____________MAAARAttPADGEEPAPEAEALAAARER |
| Q96S59 | T163 | Sugiyama | RANBP9 RANBPM | QEKELQRRLKRLYPAVDEQEtPLPRSWsPKDKFsYIGLsQN |
| Q99426 | S163 | Sugiyama | TBCB CG22 CKAP1 | AEAAQRLAEEKAQASSIPVGsRCEVRAAGQSPRRGTVMYVG |
| Q99459 | T385 | Sugiyama | CDC5L KIAA0432 PCDC5RP | EAQNLMALtNVDtPLKGGLNtPLHEsDFsGVtPQRQVVQtP |
| Q99459 | T396 | Sugiyama | CDC5L KIAA0432 PCDC5RP | DtPLKGGLNtPLHEsDFsGVtPQRQVVQtPNtVLstPFRtP |
| Q99460 | S315 | Sugiyama | PSMD1 | DsMEtEEKTSsAFVGKtPEAsPEPKDQTLKMIKILSGEMAI |
| Q99460 | T311 | Sugiyama | PSMD1 | EKDsDsMEtEEKTSsAFVGKtPEAsPEPKDQTLKMIKILSG |
| Q99543 | S275 | Sugiyama | DNAJC2 MPHOSPH11 MPP11 ZRF1 | RAQRKKEEMNRIRtLVDNAysCDPRIKKFKEEEKAKKEAEK |
| Q99598 | S33 | Sugiyama | TSNAX TRAX | RKHDNFPHNQRREGKDVNsssPVMLAFKSFQQELDARHDKY |
| Q9BQE3 | S439 | Sugiyama | TUBA1C TUBA6 | SEAREDMAALEKDyEEVGADsADGEDEGEEy__________ |
| Q9BQG0 | S1163 | Sugiyama | MYBBP1A P160 | GVQRPKLEKKDAKEIPsAtQsPIsKKRKKKGFLPETKKRKK |
| Q9BSJ8 | S1034 | Sugiyama | ESYT1 FAM62A KIAA0747 MBC2 | LLPDKNRGTKRRTSQKKRtLsPEFNERFEWELPLDEAQRRK |
| Q9BTC0 | T1469 | Sugiyama | DIDO1 C20orf158 DATF1 KIAA0333 | CADVRRNsVERPAEPVAGAAtPsLVEQQKMLEELNKQIEEQ |
| Q9BTW9 | S511 | Sugiyama | TBCD KIAA0988 SSD1 TFCD PP1096 | SSALVIAAVFDRDINCRRAAsAAFQENVGRQGTFPHGIDIL |
| Q9BVA1 | S115 | Sugiyama | TUBB2B | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q9BY44 | S506 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | KNQRKHEAKKAAKQEARsDKsPDLAPtPAPQstPRNtVsQs |
| Q9BY44 | T512 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | EAKKAAKQEARsDKsPDLAPtPAPQstPRNtVsQsIsGDPE |
| Q9BYG3 | T234 | Sugiyama | NIFK MKI67IP NOPP34 | KKKVsGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELND |
| Q9BYG3 | T238 | Sugiyama | NIFK MKI67IP NOPP34 | sGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELNDDDKD |
| Q9BYN0 | T133 | Sugiyama | SRXN1 C20orf139 SRX SRX1 | IPAKLVQSTLSDLRVYLGAStPDLQ________________ |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9C0C2 | S1103 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ |
| Q9C0C2 | S1174 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | ttAGsVDWTDQLGLRNLEVssCVGsGGssEAREsAVGQMGW |
| Q9C0C2 | S435 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | DAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAALPQGQG |
| Q9C0C2 | S504 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | PSGLGVWRLDsPPPsPItEAsEAAEAAEAGNLAVSSREEGV |
| Q9C0C2 | S601 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | LPLQQAEERyEsQEPLAGQEsPLPLATREAALPILEPVLGQ |
| Q9C0C2 | S672 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | TLARAETtQARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsP |
| Q9C0C2 | S680 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | QARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsPPPsGGGAR |
| Q9C0C2 | S717 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | GGARRGAGAELKDtQsPstCsEGLLGWsQKDLQSEFGITGD |
| Q9GZL7 | S415 | Sugiyama | WDR12 | TDTGLLLSGGADNKLYSYRYsPTTSHVGA____________ |
| Q9H2G2 | S1219 | Sugiyama | SLK KIAA0204 STK2 | EQEVFFKMTGEsECLNPStQsRISKFyPIPsLHstGs____ |
| Q9H2G2 | T1217 | Sugiyama | SLK KIAA0204 STK2 | LQEQEVFFKMTGEsECLNPStQsRISKFyPIPsLHstGs__ |
| Q9H2U1 | S283 | Sugiyama | DHX36 DDX36 KIAA1488 MLEL1 RHAU | QPRRIsAISVAERVAAERAEsCGSGNSTGYQIRLQSRLPRK |
| Q9H2U2 | S317 | Sugiyama | PPA2 HSPC124 | DSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK___ |
| Q9H488 | S264 | Sugiyama | POFUT1 FUT12 KIAA0180 | DWKNACAMLKDGTAGSHFMAsPQCVGySRSTAAPLTMTMCL |
| Q9H4A3 | S1261 | Sugiyama | WNK1 HSN2 KDP KIAA0344 PRKWNK1 | GIPTSSLTQVVHSAGRRFIVsPVPEsRLRESKVFPSEITDT |
| Q9H4A3 | S1266 | Sugiyama | WNK1 HSN2 KDP KIAA0344 PRKWNK1 | SLTQVVHSAGRRFIVsPVPEsRLRESKVFPSEITDTVAAst |
| Q9H4A4 | S19 | Sugiyama | RNPEP APB | __MAsGEHsPGsGAARRPLHsAQAVDVAsAsNFRAFELLHL |
| Q9H4A4 | S27 | Sugiyama | RNPEP APB | sPGsGAARRPLHsAQAVDVAsAsNFRAFELLHLHLDLRAEF |
| Q9H4A5 | S112 | Sugiyama | GOLPH3L GPP34R | EPPTMRKKRLLDRKVLLKsDsPTGDVLLDETLKHIKATEPT |
| Q9H4G0 | S784 | Sugiyama | EPB41L1 KIAA0338 | KGAAAMIPGPQTVATEIRsLsPIIGKDVLtstyGAtAEtLS |
| Q9H6Y2 | S42 | Sugiyama | WDR55 | MEAPTRIRDtPEDIVLEAPAsGLAFHPARDLLAAGDVDGDV |
| Q9H6Y2 | T31 | Sugiyama | WDR55 | EDGsDEEDPDsMEAPTRIRDtPEDIVLEAPAsGLAFHPARD |
| Q9H788 | S316 | Sugiyama | SH2D4A PPP1R38 SH2A | NSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRAG |
| Q9H7N4 | S498 | Sugiyama | SCAF1 SFRS19 SRA1 | GGLDLRRKILTQRRERyRQRsPsPAPAPAPAAAAGPPTRKK |
| Q9H7N4 | S500 | Sugiyama | SCAF1 SFRS19 SRA1 | LDLRRKILTQRRERyRQRsPsPAPAPAPAAAAGPPTRKKSR |
| Q9HA77 | S544 | Sugiyama | CARS2 OK/SW-cl.10 | EACDTLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG |
| Q9HA77 | S545 | Sugiyama | CARS2 OK/SW-cl.10 | ACDTLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG_ |
| Q9HA77 | S548 | Sugiyama | CARS2 OK/SW-cl.10 | TLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG____ |
| Q9NP81 | S53 | Sugiyama | SARS2 SARSM | SFTTEKRNRNLLYEYAREGysALPQLDIERFCACPEEAAHA |
| Q9NPD8 | T44 | Sugiyama | UBE2T HSPC150 PIG50 | CWQDKDQMDDLRAQILGGANtPYEKGVFKLEVIIPERYPFE |
| Q9NPQ8 | T441 | Sugiyama | RIC8A | AARGLMAGGRPEGQysEDEDtDtDEyKEAKAsINPVTGRVE |
| Q9NR19 | S28 | Sugiyama | ACSS2 ACAS2 | VRsGsGSRGQEEAGAGGRARsWsPPPEVsRSAHVPSLQRYR |
| Q9NR19 | S30 | Sugiyama | ACSS2 ACAS2 | sGsGSRGQEEAGAGGRARsWsPPPEVsRSAHVPSLQRYREL |
| Q9NR20 | Y264 | Sugiyama | DYRK4 | ASVKVIDFGSSCYEHQKVYTyIQSRFYRSPEVILGHPYDVA |
| Q9NR28 | S230 | Sugiyama | DIABLO SMAC | EAQIEELRQKTQEEGEERAEsEQEAyLRED___________ |
| Q9NR30 | S706 | Sugiyama | DDX21 | PTASVTEIQEKWHDSRRWQLsVATEQPELEGPREGYGGFRG |
| Q9NRX4 | S80 | Sugiyama | PHPT1 PHP14 CGI-202 HSPC141 | VSGDMQKQGCDCECLGGGRIsHQSQDKKIHVyGysMAyGPA |
| Q9NSE4 | S176 | Sugiyama | IARS2 | HGLPIEIKVLSELGREAQNLsAMEIRKKARSFAKAAIEKQK |
| Q9NTJ3 | T44 | Sugiyama | SMC4 CAPC SMC4L1 | DGAssDAEPEPPsGRtEsPAtAAEtAsEELDNRSLEEILNS |
| Q9NXH9 | S524 | Sugiyama | TRMT1 | KECPVKRERLsETsPAFRILsVEPRLQANFTIREDANPSSR |
| Q9NY33 | S218 | Sugiyama | DPP3 | tRLFKEVDGEGKPYYEVRLAsVLGSEPsLDsEVTSKLKSYE |
| Q9NY33 | S242 | Sugiyama | DPP3 | SEPsLDsEVTSKLKSYEFRGsPFQVTRGDyAPILQKVVEQL |
| Q9NYM9 | S9 | Sugiyama | BET1L GS15 | ____________MADWARAQsPGAVEEILDRENKRMADSLA |
| Q9NZB2 | S849 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | ADQAAKVEKMRQSVLEGLsFsRQSHTLPFPPPPALPFYPAS |
| Q9NZT2 | S349 | Sugiyama | OGFR | TCGPEHSKGGGRVDEGPQPRsVEPQDAGPLERsQGDEAGGH |
| Q9P2E9 | S1276 | Sugiyama | RRBP1 KIAA1398 | QQLSEMKSHVEDGDIAGAPAssPEAPPAEQDPVQLKTQLEW |
| Q9P2E9 | S1277 | Sugiyama | RRBP1 KIAA1398 | QLSEMKSHVEDGDIAGAPAssPEAPPAEQDPVQLKTQLEWT |
| Q9UBR2 | S78 | Sugiyama | CTSZ | SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST |
| Q9UBR2 | T80 | Sugiyama | CTSZ | ADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHASTSA |
| Q9UGI8 | S214 | Sugiyama | TES | LPCEMDAQGPKQMNIPGGDRstPAAVGAMEDKSAEHKRTQY |
| Q9UGP4 | S668 | Sugiyama | LIMD1 | LEDHLFCHsCHVKRLEKRPsstALHQHHF____________ |
| Q9UGP4 | T669 | Sugiyama | LIMD1 | EDHLFCHsCHVKRLEKRPsstALHQHHF_____________ |
| Q9UGV2 | S334 | Sugiyama | NDRG3 | GYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsDG |
| Q9UGV2 | S341 | Sugiyama | NDRG3 | MTRLARsRtHstsssLGsGEsPFsRsVtsNQsDGtQESCEs |
| Q9UGV2 | S344 | Sugiyama | NDRG3 | LARsRtHstsssLGsGEsPFsRsVtsNQsDGtQESCEsPDV |
| Q9UGV2 | S361 | Sugiyama | NDRG3 | sPFsRsVtsNQsDGtQESCEsPDVLDRHQTMEVsC______ |
| Q9UGV2 | T329 | Sugiyama | NDRG3 | FLQGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVts |
| Q9UHD2 | S527 | SIGNOR|EPSD|PSP | TBK1 NAK | RLsssQGTIETSLQDIDSRLsPGGsLADAWAHQEGTHPKDR |
| Q9UHI6 | T705 | Sugiyama | DDX20 DP103 GEMIN3 | sEstPVDDRIsLEQPPNGsDtPNPEKyQEsPGIQMKTRLKE |
| Q9UHR4 | S251 | Sugiyama | BAIAP2L1 IRTKS | DAIKVPEKIMNMIEEIKtPAstPVsGtPQAsPMIERSNVVR |
| Q9UHR4 | T257 | Sugiyama | BAIAP2L1 IRTKS | EKIMNMIEEIKtPAstPVsGtPQAsPMIERSNVVRKDyDtL |
| Q9UHV9 | S22 | Sugiyama | PFDN2 PFD2 HSPC231 | AENSGRAGKssGSGAGKGAVsAEQVIAGFNRLRQEQRGLAS |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UII2 | S63 | Sugiyama | ATP5IF1 ATPI ATPIF1 | AGGAFGKREQAEEERyFRAQsREQLAALKKHHEEEIVHHKK |
| Q9UIQ6 | S51 | Sugiyama | LNPEP OTASE | AKEPCLHPLEPDEVEyEPRGsRLLVRGLGEHEMEEDEEDyE |
| Q9UKG1 | S393 | Sugiyama | APPL1 APPL DIP13A KIAA1428 | ISKQIyLSENPEETAARVNQsALEAVtPsPsFQQRHEsLRP |
| Q9UKG1 | T399 | Sugiyama | APPL1 APPL DIP13A KIAA1428 | LSENPEETAARVNQsALEAVtPsPsFQQRHEsLRPAAGQSR |
| Q9UKS6 | S319 | Sugiyama | PACSIN3 | FEEWsLDtQRtIsRKEKGGRsPDEVtLtsIVPTRDGTAPPP |
| Q9ULD2 | S1264 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | RsPtssAIPLQsPRNsGsFPsPsIsPR______________ |
| Q9ULD2 | S1268 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | ssAIPLQsPRNsGsFPsPsIsPR__________________ |
| Q9UNX3 | S32 | Sugiyama | RPL26L1 RPL26P1 | sKNRKRHFNAPSHVRRKIMssPLSKELRQKYNVRSMPIRKD |
| Q9UNZ2 | S176 | Sugiyama | NSFL1C UBXN2C | RLGAAPEEEsAyVAGEKRQHssQDVHVVLKLWKsGFsLDNG |
| Q9UPQ0 | S210 | Sugiyama | LIMCH1 KIAA1102 | sLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVVLRGssDGRG |
| Q9UPQ0 | S212 | Sugiyama | LIMCH1 KIAA1102 | sPPRHGRDDsFDsLDsFGsRsRQtPsPDVVLRGssDGRGsD |
| Q9UPQ0 | S217 | Sugiyama | LIMCH1 KIAA1102 | GRDDsFDsLDsFGsRsRQtPsPDVVLRGssDGRGsDsEsDL |
| Q9UQ35 | S1103 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sPsLQSKSQTsPKGGRsRsssPVtELAsRsPIRQDRGEFsA |
| Q9UQ35 | S1318 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | VPsMASSWGGPHFsPEHKELsNsPLRENsFGsPLEFRNsGP |
| Q9UQ35 | S1329 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | HFsPEHKELsNsPLRENsFGsPLEFRNsGPLGTEMNtGFss |
| Q9UQ35 | S1541 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | ssVDQKtVARtPLGQRsRsGssQELDVKPsAsPQERsEsDs |
| Q9UQ35 | S1552 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | PLGQRsRsGssQELDVKPsAsPQERsEsDssPDSKAKTRTP |
| Q9Y230 | S358 | Sugiyama | RUVBL2 INO80J TIP48 TIP49B CGI-46 | TSYQsPHGIPIDLLDRLLIVsTtPySEKDTKQILRIRCEEE |
| Q9Y230 | S43 | Sugiyama | RUVBL2 INO80J TIP48 TIP49B CGI-46 | GAHSHIRGLGLDDALEPRQAsQGMVGQLAARRAAGVVLEMI |
| Q9Y230 | Y362 | Sugiyama | RUVBL2 INO80J TIP48 TIP49B CGI-46 | sPHGIPIDLLDRLLIVsTtPySEKDTKQILRIRCEEEDVEM |
| Q9Y262 | S249 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | NVLHSLVDKSNINRQLEVytsGGDPEsVAGEyGRHSLYKML |
| Q9Y262 | T248 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | LNVLHSLVDKSNINRQLEVytsGGDPEsVAGEyGRHSLYKM |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2K6 | S373 | Sugiyama | USP20 KIAA1003 LSFR3A VDU2 | AMAALDDQPAEAQPPsPRsssPCRtPEPDNDAHLRSSsRPC |
| Q9Y2K6 | T377 | Sugiyama | USP20 KIAA1003 LSFR3A VDU2 | LDDQPAEAQPPsPRsssPCRtPEPDNDAHLRSSsRPCsPVH |
| Q9Y2V2 | S30 | GPS6|SIGNOR|EPSD|PSP | CARHSP1 | QPPtHQAsVGLLDtPRsRERsPsPLRGNVVPsPLPtRRtRt |
| Q9Y2V2 | S32 | GPS6|SIGNOR|EPSD|PSP | CARHSP1 | PtHQAsVGLLDtPRsRERsPsPLRGNVVPsPLPtRRtRtFs |
| Q9Y2V2 | S41 | GPS6|SIGNOR|EPSD|PSP | CARHSP1 | LDtPRsRERsPsPLRGNVVPsPLPtRRtRtFsAtVRASQGP |
| Q9Y2W1 | S234 | Sugiyama | THRAP3 BCLAF2 TRAP150 | TKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERsPALKsP |
| Q9Y2W2 | S237 | Sugiyama | WBP11 NPWBP SIPP1 SNP70 | RKVGFALDLPPRRRDEDMLysPELAQRGHDDDVSSTSEDDG |
| Q9Y3F4 | S228 | Sugiyama | STRAP MAWD UNRIP | FHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLy |
| Q9Y5J9 | S50 | Sugiyama | TIMM8B DDP2 DDPL TIM8B | HHFMELCWDKCVEKPGNRLDsRTENCLsSCVDRFIDTTLAI |
| Q9Y5M8 | S257 | Sugiyama | SRPRB PSEC0230 | LPLKVEFLECSAKGGRGDVGsADIQDLEKWLAKIA______ |
| Q9Y5T5 | S552 | Sugiyama | USP16 MSTP039 | TEEVDMKNINMDNDLEVLtssPtRNLNGAYLTEGSNGEVDI |
| Q9Y617 | S226 | Sugiyama | PSAT1 PSA | GVTVVIVRDDLLGFALRECPsVLEyKVQAGNSSLYNTPPCF |
| Q9Y6M1 | S162 | Sugiyama | IGF2BP2 IMP2 VICKZ2 | GHQFENYsFKISYIPDEEVssPsPPQRAQRGDHSSREQGHA |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Chromatin organization | R-HSA-4839726 | 1.765229e-08 | 7.753 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 5.148115e-08 | 7.288 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.599197e-06 | 5.585 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.921976e-05 | 4.716 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 4.374533e-05 | 4.359 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 1.017810e-04 | 3.992 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.349187e-04 | 3.870 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 1.799407e-04 | 3.745 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 3.070499e-04 | 3.513 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 3.470642e-04 | 3.460 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 5.661352e-04 | 3.247 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 6.139066e-04 | 3.212 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 6.243213e-04 | 3.205 | 1 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 7.021350e-04 | 3.154 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 7.083047e-04 | 3.150 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.128772e-03 | 2.947 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 1.346811e-03 | 2.871 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 1.484230e-03 | 2.828 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.996436e-03 | 2.700 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 2.174513e-03 | 2.663 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 2.212672e-03 | 2.655 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 2.330030e-03 | 2.633 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.586901e-03 | 2.587 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 2.467747e-03 | 2.608 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 2.546763e-03 | 2.594 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 3.016668e-03 | 2.520 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 3.016668e-03 | 2.520 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 3.127869e-03 | 2.505 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 3.127869e-03 | 2.505 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 3.774106e-03 | 2.423 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 4.365294e-03 | 2.360 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 4.461036e-03 | 2.351 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 4.682274e-03 | 2.330 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 4.704650e-03 | 2.327 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 4.868308e-03 | 2.313 | 0 | 0 |
| M Phase | R-HSA-68886 | 5.292616e-03 | 2.276 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 5.873744e-03 | 2.231 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 5.873744e-03 | 2.231 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 5.873744e-03 | 2.231 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 5.539146e-03 | 2.257 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 5.962449e-03 | 2.225 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 6.609568e-03 | 2.180 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 6.914143e-03 | 2.160 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 7.015264e-03 | 2.154 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 7.282835e-03 | 2.138 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 7.589118e-03 | 2.120 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 7.589118e-03 | 2.120 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 7.329651e-03 | 2.135 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 7.836810e-03 | 2.106 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 8.422345e-03 | 2.075 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 9.099324e-03 | 2.041 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 9.273984e-03 | 2.033 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.013840e-02 | 1.994 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.020119e-02 | 1.991 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 1.082135e-02 | 1.966 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 1.275580e-02 | 1.894 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.283165e-02 | 1.892 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.278317e-02 | 1.893 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 1.283165e-02 | 1.892 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 1.246555e-02 | 1.904 | 1 | 0 |
| Gastrulation | R-HSA-9758941 | 1.266697e-02 | 1.897 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 1.353527e-02 | 1.869 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 1.353527e-02 | 1.869 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 1.353527e-02 | 1.869 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.369772e-02 | 1.863 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.369772e-02 | 1.863 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 1.369772e-02 | 1.863 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 1.437800e-02 | 1.842 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.502713e-02 | 1.823 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.521714e-02 | 1.818 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.521714e-02 | 1.818 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.521053e-02 | 1.818 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.584997e-02 | 1.800 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 1.637117e-02 | 1.786 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.713379e-02 | 1.766 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 1.718300e-02 | 1.765 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.747245e-02 | 1.758 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.765593e-02 | 1.753 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 1.791774e-02 | 1.747 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 1.883850e-02 | 1.725 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 1.883850e-02 | 1.725 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 2.042240e-02 | 1.690 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 2.114397e-02 | 1.675 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 2.095557e-02 | 1.679 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 2.095557e-02 | 1.679 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 2.219535e-02 | 1.654 | 1 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 2.101573e-02 | 1.677 | 1 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 2.112728e-02 | 1.675 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 2.226989e-02 | 1.652 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.437686e-02 | 1.613 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.437686e-02 | 1.613 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.437686e-02 | 1.613 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.437686e-02 | 1.613 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.437686e-02 | 1.613 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 2.392065e-02 | 1.621 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.435203e-02 | 1.613 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 2.495780e-02 | 1.603 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 2.779861e-02 | 1.556 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.812761e-02 | 1.551 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 2.831420e-02 | 1.548 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 2.850707e-02 | 1.545 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 3.327213e-02 | 1.478 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 3.327213e-02 | 1.478 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 3.327213e-02 | 1.478 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 3.274211e-02 | 1.485 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 3.240459e-02 | 1.489 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 3.207947e-02 | 1.494 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 3.313580e-02 | 1.480 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 3.274211e-02 | 1.485 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 3.240459e-02 | 1.489 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 3.158709e-02 | 1.500 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 3.449500e-02 | 1.462 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 3.495448e-02 | 1.456 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 3.563927e-02 | 1.448 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 3.577264e-02 | 1.446 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 3.619802e-02 | 1.441 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 3.620795e-02 | 1.441 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 3.903579e-02 | 1.409 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 3.659327e-02 | 1.437 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 3.958479e-02 | 1.402 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.958515e-02 | 1.402 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 3.689205e-02 | 1.433 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 3.984690e-02 | 1.400 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 4.042082e-02 | 1.393 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 4.195722e-02 | 1.377 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 4.199337e-02 | 1.377 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 4.447618e-02 | 1.352 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 4.447618e-02 | 1.352 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 4.447618e-02 | 1.352 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 4.495186e-02 | 1.347 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 4.366318e-02 | 1.360 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 4.591145e-02 | 1.338 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 4.252200e-02 | 1.371 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 4.584740e-02 | 1.339 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 4.633322e-02 | 1.334 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 4.738610e-02 | 1.324 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 4.749438e-02 | 1.323 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 4.762591e-02 | 1.322 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 5.075459e-02 | 1.295 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 5.275471e-02 | 1.278 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 5.275471e-02 | 1.278 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 5.541277e-02 | 1.256 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 5.541277e-02 | 1.256 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 5.541277e-02 | 1.256 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 5.541277e-02 | 1.256 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 5.075459e-02 | 1.295 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 5.061388e-02 | 1.296 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 5.104420e-02 | 1.292 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 5.331725e-02 | 1.273 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 5.609949e-02 | 1.251 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 5.971955e-02 | 1.224 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 5.971955e-02 | 1.224 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 5.971955e-02 | 1.224 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 6.027853e-02 | 1.220 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 6.053822e-02 | 1.218 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 6.053822e-02 | 1.218 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 6.143993e-02 | 1.212 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 6.716033e-02 | 1.173 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 7.090646e-02 | 1.149 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.924390e-02 | 1.160 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 7.007648e-02 | 1.154 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 6.820671e-02 | 1.166 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 7.090646e-02 | 1.149 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 6.387048e-02 | 1.195 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 7.101084e-02 | 1.149 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 7.101084e-02 | 1.149 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 7.180937e-02 | 1.144 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 7.180937e-02 | 1.144 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 7.231619e-02 | 1.141 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 7.231619e-02 | 1.141 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 7.231619e-02 | 1.141 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 7.282145e-02 | 1.138 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 8.356526e-02 | 1.078 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 8.356526e-02 | 1.078 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 8.356526e-02 | 1.078 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 8.356526e-02 | 1.078 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 8.356526e-02 | 1.078 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 8.356526e-02 | 1.078 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 8.356526e-02 | 1.078 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 8.356526e-02 | 1.078 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 8.356526e-02 | 1.078 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 8.356526e-02 | 1.078 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 8.356526e-02 | 1.078 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 8.356526e-02 | 1.078 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 8.018144e-02 | 1.096 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 8.195835e-02 | 1.086 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 8.129906e-02 | 1.090 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 8.018144e-02 | 1.096 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 8.245863e-02 | 1.084 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 7.768380e-02 | 1.110 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 7.583663e-02 | 1.120 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 7.828204e-02 | 1.106 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 7.496601e-02 | 1.125 | 0 | 0 |
| Drug resistance of FLT3 mutants | R-HSA-9702506 | 1.126223e-01 | 0.948 | 0 | 0 |
| FLT3 mutants bind TKIs | R-HSA-9702509 | 1.126223e-01 | 0.948 | 0 | 0 |
| sorafenib-resistant FLT3 mutants | R-HSA-9702624 | 1.126223e-01 | 0.948 | 0 | 0 |
| ponatinib-resistant FLT3 mutants | R-HSA-9702614 | 1.126223e-01 | 0.948 | 0 | 0 |
| pexidartinib-resistant FLT3 mutants | R-HSA-9702605 | 1.126223e-01 | 0.948 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 1.126223e-01 | 0.948 | 0 | 0 |
| linifanib-resistant FLT3 mutants | R-HSA-9702998 | 1.126223e-01 | 0.948 | 0 | 0 |
| semaxanib-resistant FLT3 mutants | R-HSA-9702577 | 1.126223e-01 | 0.948 | 0 | 0 |
| quizartinib-resistant FLT3 mutants | R-HSA-9702620 | 1.126223e-01 | 0.948 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 1.126223e-01 | 0.948 | 0 | 0 |
| KW2449-resistant FLT3 mutants | R-HSA-9702569 | 1.126223e-01 | 0.948 | 0 | 0 |
| tamatinib-resistant FLT3 mutants | R-HSA-9703009 | 1.126223e-01 | 0.948 | 0 | 0 |
| lestaurtinib-resistant FLT3 mutants | R-HSA-9702596 | 1.126223e-01 | 0.948 | 0 | 0 |
| tandutinib-resistant FLT3 mutants | R-HSA-9702636 | 1.126223e-01 | 0.948 | 0 | 0 |
| gilteritinib-resistant FLT3 mutants | R-HSA-9702590 | 1.126223e-01 | 0.948 | 0 | 0 |
| midostaurin-resistant FLT3 mutants | R-HSA-9702600 | 1.126223e-01 | 0.948 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.126223e-01 | 0.948 | 0 | 0 |
| crenolanib-resistant FLT3 mutants | R-HSA-9702581 | 1.126223e-01 | 0.948 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.126223e-01 | 0.948 | 0 | 0 |
| Deletions in the AXIN1 gene destabilize the destruction complex | R-HSA-5467345 | 1.126223e-01 | 0.948 | 0 | 0 |
| sunitinib-resistant FLT3 mutants | R-HSA-9702632 | 1.126223e-01 | 0.948 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 9.461466e-02 | 1.024 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 9.461466e-02 | 1.024 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 9.461466e-02 | 1.024 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 8.906866e-02 | 1.050 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 1.073705e-01 | 0.969 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.073705e-01 | 0.969 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 1.073705e-01 | 0.969 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 9.444631e-02 | 1.025 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 9.444631e-02 | 1.025 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 9.444631e-02 | 1.025 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.045929e-01 | 0.980 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.045929e-01 | 0.980 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.118577e-01 | 0.951 | 1 | 1 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 9.718396e-02 | 1.012 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 1.082190e-01 | 0.966 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 1.105363e-01 | 0.956 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 9.444631e-02 | 1.025 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 8.770778e-02 | 1.057 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 8.969576e-02 | 1.047 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 1.045929e-01 | 0.980 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 1.099100e-01 | 0.959 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 9.286610e-02 | 1.032 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.000711e-01 | 1.000 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 8.919742e-02 | 1.050 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 9.461466e-02 | 1.024 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 9.718396e-02 | 1.012 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 1.083556e-01 | 0.965 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 8.481990e-02 | 1.072 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 9.444631e-02 | 1.025 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 9.801357e-02 | 1.009 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 1.210268e-01 | 0.917 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 1.210268e-01 | 0.917 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 1.210268e-01 | 0.917 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 1.210268e-01 | 0.917 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 1.193349e-01 | 0.923 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 1.193349e-01 | 0.923 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 1.193349e-01 | 0.923 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 1.193349e-01 | 0.923 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.272108e-01 | 0.895 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 1.272108e-01 | 0.895 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 1.170511e-01 | 0.932 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 1.170511e-01 | 0.932 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.170511e-01 | 0.932 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.170511e-01 | 0.932 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 1.206594e-01 | 0.918 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.339642e-01 | 0.873 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 1.237708e-01 | 0.907 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 1.210268e-01 | 0.917 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.169172e-01 | 0.932 | 1 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 1.206758e-01 | 0.918 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 1.206758e-01 | 0.918 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 1.206758e-01 | 0.918 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 1.206758e-01 | 0.918 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 1.170511e-01 | 0.932 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 1.193349e-01 | 0.923 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 1.302424e-01 | 0.885 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.402564e-01 | 0.853 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 1.193349e-01 | 0.923 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 1.376080e-01 | 0.861 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 1.227409e-01 | 0.911 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 1.206758e-01 | 0.918 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 1.394733e-01 | 0.856 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 1.265144e-01 | 0.898 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.181717e-01 | 0.927 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.289869e-01 | 0.889 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.427673e-01 | 0.845 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.125666e-01 | 0.673 | 0 | 0 |
| Defective Mismatch Repair Associated With PMS2 | R-HSA-5632987 | 2.125666e-01 | 0.673 | 0 | 0 |
| Defective Mismatch Repair Associated With MLH1 | R-HSA-5545483 | 2.125666e-01 | 0.673 | 0 | 0 |
| Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI) | R-HSA-9036092 | 2.125666e-01 | 0.673 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.125666e-01 | 0.673 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 1.616766e-01 | 0.791 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 1.616766e-01 | 0.791 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 1.616766e-01 | 0.791 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 1.616766e-01 | 0.791 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 1.616766e-01 | 0.791 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 3.012595e-01 | 0.521 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 3.012595e-01 | 0.521 | 0 | 0 |
| Defective GFPT1 causes CMSTA1 | R-HSA-4085023 | 3.012595e-01 | 0.521 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 3.012595e-01 | 0.521 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 3.012595e-01 | 0.521 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 3.012595e-01 | 0.521 | 0 | 0 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P | R-HSA-6791462 | 3.012595e-01 | 0.521 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5619101 | 3.012595e-01 | 0.521 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5660686 | 3.012595e-01 | 0.521 | 0 | 0 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P | R-HSA-6791055 | 3.012595e-01 | 0.521 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.012595e-01 | 0.521 | 0 | 0 |
| Defective MMADHC causes MMAHCD | R-HSA-3359473 | 3.012595e-01 | 0.521 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 2.043223e-01 | 0.690 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 2.043223e-01 | 0.690 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 2.043223e-01 | 0.690 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 2.043223e-01 | 0.690 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 1.746693e-01 | 0.758 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 1.746693e-01 | 0.758 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 2.479994e-01 | 0.606 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 2.479994e-01 | 0.606 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 2.479994e-01 | 0.606 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 3.799671e-01 | 0.420 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 3.799671e-01 | 0.420 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.799671e-01 | 0.420 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 3.799671e-01 | 0.420 | 0 | 0 |
| HHAT G278V doesn't palmitoylate Hh-Np | R-HSA-5658034 | 3.799671e-01 | 0.420 | 0 | 0 |
| Defective ABCD1 causes ALD | R-HSA-5684045 | 3.799671e-01 | 0.420 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 3.799671e-01 | 0.420 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.709417e-01 | 0.767 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 2.919351e-01 | 0.535 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 2.355591e-01 | 0.628 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 2.355591e-01 | 0.628 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 2.355591e-01 | 0.628 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 2.355591e-01 | 0.628 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 2.355591e-01 | 0.628 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 2.355591e-01 | 0.628 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 1.535629e-01 | 0.814 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 2.190306e-01 | 0.659 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 2.672686e-01 | 0.573 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 2.672686e-01 | 0.573 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 2.672686e-01 | 0.573 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 3.355174e-01 | 0.474 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 3.355174e-01 | 0.474 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 3.355174e-01 | 0.474 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 3.355174e-01 | 0.474 | 0 | 0 |
| Defective MMACHC causes MAHCC | R-HSA-3359474 | 4.498130e-01 | 0.347 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 4.498130e-01 | 0.347 | 0 | 0 |
| Defective GSS causes GSS deficiency | R-HSA-5579006 | 4.498130e-01 | 0.347 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 4.498130e-01 | 0.347 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.441395e-01 | 0.841 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 1.441395e-01 | 0.841 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 2.443017e-01 | 0.612 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 2.994256e-01 | 0.524 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 2.994256e-01 | 0.524 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 2.994256e-01 | 0.524 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 2.994256e-01 | 0.524 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 2.994256e-01 | 0.524 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 2.994256e-01 | 0.524 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 1.739194e-01 | 0.760 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.701740e-01 | 0.568 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 3.782689e-01 | 0.422 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 3.782689e-01 | 0.422 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 3.782689e-01 | 0.422 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 3.782689e-01 | 0.422 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 3.782689e-01 | 0.422 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 2.456296e-01 | 0.610 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 3.317653e-01 | 0.479 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 3.317653e-01 | 0.479 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 3.317653e-01 | 0.479 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 3.317653e-01 | 0.479 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 2.678624e-01 | 0.572 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 2.678624e-01 | 0.572 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 2.047477e-01 | 0.689 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 2.047477e-01 | 0.689 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.866676e-01 | 0.729 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.024459e-01 | 0.694 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 2.201751e-01 | 0.657 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 3.230990e-01 | 0.491 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 3.640499e-01 | 0.439 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 3.640499e-01 | 0.439 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 4.198240e-01 | 0.377 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 4.198240e-01 | 0.377 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 5.117944e-01 | 0.291 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 5.117944e-01 | 0.291 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.117944e-01 | 0.291 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 5.117944e-01 | 0.291 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 5.117944e-01 | 0.291 | 0 | 0 |
| Signaling by LRP5 mutants | R-HSA-5339717 | 5.117944e-01 | 0.291 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 1.995475e-01 | 0.700 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 2.360167e-01 | 0.627 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 2.360167e-01 | 0.627 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 2.360167e-01 | 0.627 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 1.814326e-01 | 0.741 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 3.498580e-01 | 0.456 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 3.498580e-01 | 0.456 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 3.498580e-01 | 0.456 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 3.498580e-01 | 0.456 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 3.498580e-01 | 0.456 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 3.498580e-01 | 0.456 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 3.498580e-01 | 0.456 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 1.626733e-01 | 0.789 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 1.626733e-01 | 0.789 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 3.960691e-01 | 0.402 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 3.960691e-01 | 0.402 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 3.960691e-01 | 0.402 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 3.960691e-01 | 0.402 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 3.960691e-01 | 0.402 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.854185e-01 | 0.732 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 2.687922e-01 | 0.571 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 3.366703e-01 | 0.473 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 2.344102e-01 | 0.630 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 2.344102e-01 | 0.630 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 3.766334e-01 | 0.424 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 4.599100e-01 | 0.337 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 4.599100e-01 | 0.337 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 3.027632e-01 | 0.519 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 4.276395e-01 | 0.369 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.033435e-01 | 0.518 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.703146e-01 | 0.431 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 3.703146e-01 | 0.431 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 4.066772e-01 | 0.391 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 4.586035e-01 | 0.339 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 4.983305e-01 | 0.302 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 5.667965e-01 | 0.247 | 0 | 0 |
| IRS activation | R-HSA-74713 | 5.667965e-01 | 0.247 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 5.667965e-01 | 0.247 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 5.667965e-01 | 0.247 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 5.667965e-01 | 0.247 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 3.347063e-01 | 0.475 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 4.558751e-01 | 0.341 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 3.766376e-01 | 0.424 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 4.528914e-01 | 0.344 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 3.524891e-01 | 0.453 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 4.815865e-01 | 0.317 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 5.349523e-01 | 0.272 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 3.766839e-01 | 0.424 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 4.065389e-01 | 0.391 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 4.248898e-01 | 0.372 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 3.415063e-01 | 0.467 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 5.182034e-01 | 0.285 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 4.660181e-01 | 0.332 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 5.068032e-01 | 0.295 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 5.068032e-01 | 0.295 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 5.466401e-01 | 0.262 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 5.466401e-01 | 0.262 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 5.466401e-01 | 0.262 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 5.696929e-01 | 0.244 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 5.696929e-01 | 0.244 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 6.156049e-01 | 0.211 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 6.156049e-01 | 0.211 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 6.156049e-01 | 0.211 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 6.156049e-01 | 0.211 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.156049e-01 | 0.211 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 6.156049e-01 | 0.211 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 6.156049e-01 | 0.211 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 6.156049e-01 | 0.211 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 6.156049e-01 | 0.211 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 6.156049e-01 | 0.211 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.156049e-01 | 0.211 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 4.909734e-01 | 0.309 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 5.417632e-01 | 0.266 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 6.025115e-01 | 0.220 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 6.004357e-01 | 0.222 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 6.004357e-01 | 0.222 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 5.926571e-01 | 0.227 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 6.014627e-01 | 0.221 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 6.233434e-01 | 0.205 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 6.233434e-01 | 0.205 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 6.257051e-01 | 0.204 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 6.257051e-01 | 0.204 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 6.334000e-01 | 0.198 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 6.589166e-01 | 0.181 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 6.589166e-01 | 0.181 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 6.589166e-01 | 0.181 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 6.589166e-01 | 0.181 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 6.498530e-01 | 0.187 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 6.605647e-01 | 0.180 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 6.623769e-01 | 0.179 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 6.728681e-01 | 0.172 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 6.947493e-01 | 0.158 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 6.947493e-01 | 0.158 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 6.894806e-01 | 0.161 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 6.973504e-01 | 0.157 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 6.973504e-01 | 0.157 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 6.973504e-01 | 0.157 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 6.973504e-01 | 0.157 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 6.973504e-01 | 0.157 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 7.147653e-01 | 0.146 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 2.044264e-01 | 0.689 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 3.322968e-01 | 0.478 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 3.662504e-01 | 0.436 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 6.452782e-01 | 0.190 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.821142e-01 | 0.740 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 2.263917e-01 | 0.645 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 2.443017e-01 | 0.612 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 2.047477e-01 | 0.689 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 4.297497e-01 | 0.367 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 5.061234e-01 | 0.296 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 4.033017e-01 | 0.394 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 6.050384e-01 | 0.218 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 5.061234e-01 | 0.296 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 5.061234e-01 | 0.296 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 5.646323e-01 | 0.248 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 4.066772e-01 | 0.391 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 1.824289e-01 | 0.739 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 1.579362e-01 | 0.802 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 5.696929e-01 | 0.244 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 4.820905e-01 | 0.317 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 2.047477e-01 | 0.689 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.024459e-01 | 0.694 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.024459e-01 | 0.694 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 3.640499e-01 | 0.439 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 3.599913e-01 | 0.444 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 4.888282e-01 | 0.311 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 6.623769e-01 | 0.179 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 2.595043e-01 | 0.586 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 1.478673e-01 | 0.830 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 4.291265e-01 | 0.367 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 4.980753e-01 | 0.303 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 6.025115e-01 | 0.220 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 1.752770e-01 | 0.756 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 2.994256e-01 | 0.524 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 2.856482e-01 | 0.544 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 2.856482e-01 | 0.544 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 6.782980e-01 | 0.169 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 4.082141e-01 | 0.389 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 2.479994e-01 | 0.606 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 1.945225e-01 | 0.711 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 2.058381e-01 | 0.686 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 1.897703e-01 | 0.722 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.680233e-01 | 0.775 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.712357e-01 | 0.766 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 2.843253e-01 | 0.546 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 2.925293e-01 | 0.534 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 4.888282e-01 | 0.311 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 4.756434e-01 | 0.323 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 6.156049e-01 | 0.211 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 6.647559e-01 | 0.177 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 7.080455e-01 | 0.150 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.190306e-01 | 0.659 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 4.298803e-01 | 0.367 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 1.709417e-01 | 0.767 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 2.994256e-01 | 0.524 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.024459e-01 | 0.694 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 5.969428e-01 | 0.224 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 7.206747e-01 | 0.142 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.960757e-01 | 0.708 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 4.082141e-01 | 0.389 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 4.298803e-01 | 0.367 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 6.623769e-01 | 0.179 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 2.551297e-01 | 0.593 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 5.314547e-01 | 0.275 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 6.651227e-01 | 0.177 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 3.112399e-01 | 0.507 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 1.746693e-01 | 0.758 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 2.678624e-01 | 0.572 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 4.198240e-01 | 0.377 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 5.117944e-01 | 0.291 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 3.960691e-01 | 0.402 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 4.547119e-01 | 0.342 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 5.466401e-01 | 0.262 | 0 | 0 |
| Ligand-receptor interactions | R-HSA-5632681 | 6.156049e-01 | 0.211 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 4.333037e-01 | 0.363 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 6.014627e-01 | 0.221 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 6.444472e-01 | 0.191 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 6.973504e-01 | 0.157 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 3.292606e-01 | 0.482 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 6.498530e-01 | 0.187 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 3.233035e-01 | 0.490 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 4.215246e-01 | 0.375 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 6.282799e-01 | 0.202 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 6.282799e-01 | 0.202 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 6.619039e-01 | 0.179 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 3.871756e-01 | 0.412 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 3.230990e-01 | 0.491 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 4.599100e-01 | 0.337 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 3.365972e-01 | 0.473 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 5.696929e-01 | 0.244 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 5.182034e-01 | 0.285 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 5.248392e-01 | 0.280 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 6.302838e-01 | 0.200 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 3.317653e-01 | 0.479 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 4.528914e-01 | 0.344 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 5.068032e-01 | 0.295 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 5.201317e-01 | 0.284 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 6.010663e-01 | 0.221 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 4.082141e-01 | 0.389 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 5.971823e-01 | 0.224 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 1.511708e-01 | 0.821 | 0 | 0 |
| S Phase | R-HSA-69242 | 1.465015e-01 | 0.834 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 2.043223e-01 | 0.690 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.746693e-01 | 0.758 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 2.479994e-01 | 0.606 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 1.824289e-01 | 0.739 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 2.672686e-01 | 0.573 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 5.117944e-01 | 0.291 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 2.761465e-01 | 0.559 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 2.545298e-01 | 0.594 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 5.349523e-01 | 0.272 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 4.980753e-01 | 0.303 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 6.257051e-01 | 0.204 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 6.973504e-01 | 0.157 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 6.973504e-01 | 0.157 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 6.973504e-01 | 0.157 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 7.147653e-01 | 0.146 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 3.050926e-01 | 0.516 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 6.858586e-01 | 0.164 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 4.969337e-01 | 0.304 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 6.416436e-01 | 0.193 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 4.750355e-01 | 0.323 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 3.132409e-01 | 0.504 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 3.766839e-01 | 0.424 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 5.696929e-01 | 0.244 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.640753e-01 | 0.785 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 4.566658e-01 | 0.340 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 5.314547e-01 | 0.275 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 4.349426e-01 | 0.362 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 1.616766e-01 | 0.791 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 1.616766e-01 | 0.791 | 0 | 0 |
| Inhibition of nitric oxide production | R-HSA-9636249 | 4.498130e-01 | 0.347 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 4.498130e-01 | 0.347 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.877367e-01 | 0.726 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 2.456296e-01 | 0.610 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 2.060886e-01 | 0.686 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 4.198240e-01 | 0.377 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 3.245031e-01 | 0.489 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 2.286631e-01 | 0.641 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 3.416566e-01 | 0.466 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 5.349523e-01 | 0.272 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 6.161563e-01 | 0.210 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 6.589166e-01 | 0.181 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 6.894806e-01 | 0.161 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 6.973504e-01 | 0.157 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 7.029460e-01 | 0.153 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 2.410801e-01 | 0.618 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 3.703146e-01 | 0.431 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 3.200970e-01 | 0.495 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 4.969337e-01 | 0.304 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 2.538880e-01 | 0.595 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 2.919351e-01 | 0.535 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 2.437497e-01 | 0.613 | 0 | 0 |
| Vasopressin-like receptors | R-HSA-388479 | 5.117944e-01 | 0.291 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 3.366703e-01 | 0.473 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 5.349523e-01 | 0.272 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 5.110710e-01 | 0.292 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.872361e-01 | 0.412 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 5.417632e-01 | 0.266 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 4.248898e-01 | 0.372 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 4.815865e-01 | 0.317 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 6.252285e-01 | 0.204 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 6.605647e-01 | 0.180 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 3.785789e-01 | 0.422 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 3.230990e-01 | 0.491 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 4.276395e-01 | 0.369 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 7.118684e-01 | 0.148 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 3.012595e-01 | 0.521 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 2.043223e-01 | 0.690 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 2.043223e-01 | 0.690 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 2.043223e-01 | 0.690 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 1.746693e-01 | 0.758 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 3.799671e-01 | 0.420 | 0 | 0 |
| TGFBR3 regulates activin signaling | R-HSA-9839406 | 3.799671e-01 | 0.420 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.709417e-01 | 0.767 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 2.672686e-01 | 0.573 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 4.498130e-01 | 0.347 | 0 | 0 |
| Activation of BMF and translocation to mitochondria | R-HSA-139910 | 4.498130e-01 | 0.347 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.897264e-01 | 0.722 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 3.317653e-01 | 0.479 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 2.060886e-01 | 0.686 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 2.964901e-01 | 0.528 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 4.198240e-01 | 0.377 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 5.117944e-01 | 0.291 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 5.117944e-01 | 0.291 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 1.842186e-01 | 0.735 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 1.842186e-01 | 0.735 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 2.174579e-01 | 0.663 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 4.586035e-01 | 0.339 | 0 | 0 |
| Trafficking of myristoylated proteins to the cilium | R-HSA-5624138 | 5.667965e-01 | 0.247 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 5.667965e-01 | 0.247 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 3.322968e-01 | 0.478 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 2.226754e-01 | 0.652 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 4.558751e-01 | 0.341 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 4.888282e-01 | 0.311 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 4.528914e-01 | 0.344 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 4.528914e-01 | 0.344 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 2.980965e-01 | 0.526 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 5.182034e-01 | 0.285 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 5.314547e-01 | 0.275 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 5.466401e-01 | 0.262 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 6.156049e-01 | 0.211 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 6.156049e-01 | 0.211 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 6.156049e-01 | 0.211 | 0 | 0 |
| Sensory perception of salty taste | R-HSA-9730628 | 6.156049e-01 | 0.211 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 5.417632e-01 | 0.266 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 6.894806e-01 | 0.161 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 4.050226e-01 | 0.393 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 5.958217e-01 | 0.225 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 4.120592e-01 | 0.385 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 6.858586e-01 | 0.164 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 5.958217e-01 | 0.225 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 3.994116e-01 | 0.399 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 5.398484e-01 | 0.268 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 3.138899e-01 | 0.503 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 5.337316e-01 | 0.273 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 6.334000e-01 | 0.198 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 6.747694e-01 | 0.171 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 5.398484e-01 | 0.268 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 5.398484e-01 | 0.268 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 4.599100e-01 | 0.337 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 3.322968e-01 | 0.478 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 2.856482e-01 | 0.544 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.897264e-01 | 0.722 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 2.403110e-01 | 0.619 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 7.029460e-01 | 0.153 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 1.854185e-01 | 0.732 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 7.175193e-01 | 0.144 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 6.913371e-01 | 0.160 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 6.651227e-01 | 0.177 | 0 | 0 |
| Kinesins | R-HSA-983189 | 1.962754e-01 | 0.707 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 3.766334e-01 | 0.424 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 4.599100e-01 | 0.337 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 4.087392e-01 | 0.389 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 7.206761e-01 | 0.142 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 7.155046e-01 | 0.145 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 2.213894e-01 | 0.655 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 7.175193e-01 | 0.144 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 5.629261e-01 | 0.250 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 6.243995e-01 | 0.205 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 3.960691e-01 | 0.402 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 6.668608e-01 | 0.176 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 4.888672e-01 | 0.311 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 4.909734e-01 | 0.309 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 5.117944e-01 | 0.291 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 3.766334e-01 | 0.424 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 4.599100e-01 | 0.337 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 6.156049e-01 | 0.211 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 6.232497e-01 | 0.205 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 3.793119e-01 | 0.421 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 4.703705e-01 | 0.328 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 5.312362e-01 | 0.275 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 3.300815e-01 | 0.481 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 2.045880e-01 | 0.689 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 2.028132e-01 | 0.693 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 5.617897e-01 | 0.250 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 3.895212e-01 | 0.409 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 3.625927e-01 | 0.441 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 2.975245e-01 | 0.526 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.443017e-01 | 0.612 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.994256e-01 | 0.524 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 3.782689e-01 | 0.422 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 1.897264e-01 | 0.722 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 3.640499e-01 | 0.439 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 4.599100e-01 | 0.337 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 4.033017e-01 | 0.394 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 4.586035e-01 | 0.339 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 4.586035e-01 | 0.339 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 4.983305e-01 | 0.302 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 4.983305e-01 | 0.302 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 5.667965e-01 | 0.247 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 6.842574e-01 | 0.165 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 7.118684e-01 | 0.148 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.973504e-01 | 0.157 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.973504e-01 | 0.157 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 3.766839e-01 | 0.424 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 6.444472e-01 | 0.191 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 6.954011e-01 | 0.158 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 6.782980e-01 | 0.169 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.461364e-01 | 0.835 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.746693e-01 | 0.758 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 5.209516e-01 | 0.283 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 1.746693e-01 | 0.758 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 2.919351e-01 | 0.535 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 4.198240e-01 | 0.377 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 3.960691e-01 | 0.402 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 4.232275e-01 | 0.373 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 5.182034e-01 | 0.285 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 3.960691e-01 | 0.402 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 2.977534e-01 | 0.526 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 4.660181e-01 | 0.332 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 6.064764e-01 | 0.217 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 3.355174e-01 | 0.474 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 4.498130e-01 | 0.347 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 4.198240e-01 | 0.377 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.117944e-01 | 0.291 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 5.117944e-01 | 0.291 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 2.468194e-01 | 0.608 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 4.983305e-01 | 0.302 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 5.667965e-01 | 0.247 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 5.667965e-01 | 0.247 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 5.349523e-01 | 0.272 | 0 | 0 |
| Relaxin receptors | R-HSA-444821 | 6.156049e-01 | 0.211 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 6.025115e-01 | 0.220 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 6.257051e-01 | 0.204 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 6.589166e-01 | 0.181 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 7.155046e-01 | 0.145 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 7.147653e-01 | 0.146 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 5.809333e-01 | 0.236 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 5.882024e-01 | 0.230 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 5.740683e-01 | 0.241 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 5.908472e-01 | 0.229 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 2.842213e-01 | 0.546 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 2.350166e-01 | 0.629 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 4.527646e-01 | 0.344 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 3.516341e-01 | 0.454 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 5.694970e-01 | 0.245 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 2.043223e-01 | 0.690 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 3.782689e-01 | 0.422 | 0 | 0 |
| Interleukin-38 signaling | R-HSA-9007892 | 5.117944e-01 | 0.291 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 5.667965e-01 | 0.247 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 4.888282e-01 | 0.311 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 5.696929e-01 | 0.244 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 5.696929e-01 | 0.244 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 5.696929e-01 | 0.244 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 5.696929e-01 | 0.244 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 6.156049e-01 | 0.211 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 6.156049e-01 | 0.211 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 6.973504e-01 | 0.157 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 4.705376e-01 | 0.327 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 4.747223e-01 | 0.324 | 0 | 0 |
| CREB3 factors activate genes | R-HSA-8874211 | 6.589166e-01 | 0.181 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 1.751991e-01 | 0.756 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 4.586035e-01 | 0.339 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 6.334000e-01 | 0.198 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 2.498413e-01 | 0.602 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 5.314547e-01 | 0.275 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 6.000788e-01 | 0.222 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 5.667965e-01 | 0.247 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 6.232497e-01 | 0.205 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 5.182034e-01 | 0.285 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 5.696929e-01 | 0.244 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 3.581801e-01 | 0.446 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 6.334000e-01 | 0.198 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 5.689458e-01 | 0.245 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 7.029460e-01 | 0.153 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 5.554808e-01 | 0.255 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 6.014627e-01 | 0.221 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 4.081821e-01 | 0.389 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 7.208268e-01 | 0.142 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.279372e-01 | 0.138 | 0 | 0 |
| ALKBH3 mediated reversal of alkylation damage | R-HSA-112126 | 7.314554e-01 | 0.136 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 7.314554e-01 | 0.136 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 7.314554e-01 | 0.136 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 7.314554e-01 | 0.136 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 7.314554e-01 | 0.136 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 7.314554e-01 | 0.136 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 7.314554e-01 | 0.136 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 7.314554e-01 | 0.136 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 7.314554e-01 | 0.136 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 7.314554e-01 | 0.136 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 7.314554e-01 | 0.136 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 7.314554e-01 | 0.136 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 7.314554e-01 | 0.136 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 7.314554e-01 | 0.136 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 7.351012e-01 | 0.134 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 7.378862e-01 | 0.132 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 7.378862e-01 | 0.132 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 7.380046e-01 | 0.132 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 7.382968e-01 | 0.132 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 7.382968e-01 | 0.132 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 7.382968e-01 | 0.132 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 7.382968e-01 | 0.132 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 7.391271e-01 | 0.131 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 7.463785e-01 | 0.127 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 7.463785e-01 | 0.127 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 7.488489e-01 | 0.126 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 7.500273e-01 | 0.125 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 7.526021e-01 | 0.123 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 7.537056e-01 | 0.123 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 7.537056e-01 | 0.123 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 7.541500e-01 | 0.123 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 7.541500e-01 | 0.123 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 7.541500e-01 | 0.123 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 7.574463e-01 | 0.121 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 7.574463e-01 | 0.121 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 7.574463e-01 | 0.121 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 7.574463e-01 | 0.121 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 7.601490e-01 | 0.119 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 7.601490e-01 | 0.119 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 7.601490e-01 | 0.119 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 7.601490e-01 | 0.119 | 0 | 0 |
| PKA activation | R-HSA-163615 | 7.601490e-01 | 0.119 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 7.601490e-01 | 0.119 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 7.601490e-01 | 0.119 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 7.601490e-01 | 0.119 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 7.601490e-01 | 0.119 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 7.616578e-01 | 0.118 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 7.617190e-01 | 0.118 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 7.617190e-01 | 0.118 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 7.617190e-01 | 0.118 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 7.617190e-01 | 0.118 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 7.617190e-01 | 0.118 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 7.617190e-01 | 0.118 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 7.617190e-01 | 0.118 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 7.617190e-01 | 0.118 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 7.617190e-01 | 0.118 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 7.617190e-01 | 0.118 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 7.617190e-01 | 0.118 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 7.617190e-01 | 0.118 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 7.662313e-01 | 0.116 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 7.680876e-01 | 0.115 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 7.680876e-01 | 0.115 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 7.685600e-01 | 0.114 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 7.696242e-01 | 0.114 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 7.696242e-01 | 0.114 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 7.696242e-01 | 0.114 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 7.712001e-01 | 0.113 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 7.712001e-01 | 0.113 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 7.713761e-01 | 0.113 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 7.752018e-01 | 0.111 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 7.784425e-01 | 0.109 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 7.804015e-01 | 0.108 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 7.804015e-01 | 0.108 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 7.804015e-01 | 0.108 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 7.804015e-01 | 0.108 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 7.804015e-01 | 0.108 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 7.843236e-01 | 0.106 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 7.876642e-01 | 0.104 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 7.876642e-01 | 0.104 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 7.876642e-01 | 0.104 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 7.876642e-01 | 0.104 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 7.876642e-01 | 0.104 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 7.885736e-01 | 0.103 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 7.885736e-01 | 0.103 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 7.885736e-01 | 0.103 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 7.885736e-01 | 0.103 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 7.885736e-01 | 0.103 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 7.885736e-01 | 0.103 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 7.885736e-01 | 0.103 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 7.885736e-01 | 0.103 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 7.885736e-01 | 0.103 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 7.885736e-01 | 0.103 | 0 | 0 |
| Arachidonate production from DAG | R-HSA-426048 | 7.885736e-01 | 0.103 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 7.885736e-01 | 0.103 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 7.885736e-01 | 0.103 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 7.885736e-01 | 0.103 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 7.885736e-01 | 0.103 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 7.885736e-01 | 0.103 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 7.902869e-01 | 0.102 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 7.924177e-01 | 0.101 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 7.973876e-01 | 0.098 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 7.982658e-01 | 0.098 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 7.982658e-01 | 0.098 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 7.991373e-01 | 0.097 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 7.991373e-01 | 0.097 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 7.991373e-01 | 0.097 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 7.991373e-01 | 0.097 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 7.998102e-01 | 0.097 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 8.031323e-01 | 0.095 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 8.031323e-01 | 0.095 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 8.043336e-01 | 0.095 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 8.094918e-01 | 0.092 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 8.094918e-01 | 0.092 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 8.094918e-01 | 0.092 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 8.098139e-01 | 0.092 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 8.098139e-01 | 0.092 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 8.114705e-01 | 0.091 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 8.114705e-01 | 0.091 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 8.114705e-01 | 0.091 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 8.124030e-01 | 0.090 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 8.124030e-01 | 0.090 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 8.124030e-01 | 0.090 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 8.124030e-01 | 0.090 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 8.124030e-01 | 0.090 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 8.124030e-01 | 0.090 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 8.124030e-01 | 0.090 | 0 | 0 |
| LGI-ADAM interactions | R-HSA-5682910 | 8.124030e-01 | 0.090 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 8.124030e-01 | 0.090 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 8.124030e-01 | 0.090 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 8.124030e-01 | 0.090 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 8.124030e-01 | 0.090 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 8.164408e-01 | 0.088 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 8.164408e-01 | 0.088 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 8.164408e-01 | 0.088 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 8.164408e-01 | 0.088 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 8.164408e-01 | 0.088 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 8.164408e-01 | 0.088 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 8.164408e-01 | 0.088 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 8.197693e-01 | 0.086 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.210124e-01 | 0.086 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 8.233235e-01 | 0.084 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 8.239593e-01 | 0.084 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 8.273173e-01 | 0.082 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 8.280552e-01 | 0.082 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 8.286411e-01 | 0.082 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 8.307026e-01 | 0.081 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 8.309959e-01 | 0.080 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 8.323970e-01 | 0.080 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 8.323970e-01 | 0.080 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 8.335479e-01 | 0.079 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 8.335479e-01 | 0.079 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 8.335479e-01 | 0.079 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 8.335479e-01 | 0.079 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 8.335479e-01 | 0.079 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 8.335479e-01 | 0.079 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 8.335479e-01 | 0.079 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 8.335479e-01 | 0.079 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 8.335479e-01 | 0.079 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 8.335479e-01 | 0.079 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 8.357553e-01 | 0.078 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 8.357553e-01 | 0.078 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 8.357553e-01 | 0.078 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 8.357553e-01 | 0.078 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 8.383486e-01 | 0.077 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 8.393078e-01 | 0.076 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 8.393078e-01 | 0.076 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 8.393078e-01 | 0.076 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 8.404365e-01 | 0.075 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 8.408903e-01 | 0.075 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 8.417453e-01 | 0.075 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 8.439408e-01 | 0.074 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 8.439408e-01 | 0.074 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 8.468825e-01 | 0.072 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 8.468825e-01 | 0.072 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 8.470896e-01 | 0.072 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 8.470896e-01 | 0.072 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 8.470896e-01 | 0.072 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 8.470896e-01 | 0.072 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 8.470896e-01 | 0.072 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 8.470896e-01 | 0.072 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 8.491409e-01 | 0.071 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 8.495296e-01 | 0.071 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 8.497124e-01 | 0.071 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 8.497124e-01 | 0.071 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 8.497124e-01 | 0.071 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 8.497124e-01 | 0.071 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 8.497124e-01 | 0.071 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 8.518098e-01 | 0.070 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 8.522260e-01 | 0.069 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 8.523106e-01 | 0.069 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 8.523106e-01 | 0.069 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 8.523106e-01 | 0.069 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 8.523106e-01 | 0.069 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 8.523106e-01 | 0.069 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.523106e-01 | 0.069 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 8.523106e-01 | 0.069 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.523106e-01 | 0.069 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 8.523106e-01 | 0.069 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 8.558115e-01 | 0.068 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 8.558115e-01 | 0.068 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 8.564289e-01 | 0.067 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 8.572206e-01 | 0.067 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 8.581283e-01 | 0.066 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 8.585429e-01 | 0.066 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 8.606006e-01 | 0.065 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 8.606006e-01 | 0.065 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 8.606006e-01 | 0.065 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 8.607578e-01 | 0.065 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 8.646148e-01 | 0.063 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 8.648632e-01 | 0.063 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 8.668843e-01 | 0.062 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 8.668843e-01 | 0.062 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 8.668843e-01 | 0.062 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 8.668843e-01 | 0.062 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 8.669411e-01 | 0.062 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 8.669411e-01 | 0.062 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 8.689593e-01 | 0.061 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 8.689593e-01 | 0.061 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 8.689593e-01 | 0.061 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 8.689593e-01 | 0.061 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 8.689593e-01 | 0.061 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 8.689593e-01 | 0.061 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 8.689593e-01 | 0.061 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 8.689593e-01 | 0.061 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 8.689593e-01 | 0.061 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 8.689593e-01 | 0.061 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.689593e-01 | 0.061 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 8.704129e-01 | 0.060 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 8.730098e-01 | 0.059 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 8.730098e-01 | 0.059 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 8.730098e-01 | 0.059 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 8.730098e-01 | 0.059 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 8.730098e-01 | 0.059 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 8.741427e-01 | 0.058 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 8.762511e-01 | 0.057 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 8.762511e-01 | 0.057 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 8.765042e-01 | 0.057 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 8.765042e-01 | 0.057 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 8.765967e-01 | 0.057 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 8.786035e-01 | 0.056 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 8.837321e-01 | 0.054 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 8.837321e-01 | 0.054 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 8.837321e-01 | 0.054 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 8.837321e-01 | 0.054 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 8.837321e-01 | 0.054 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 8.837321e-01 | 0.054 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 8.843937e-01 | 0.053 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 8.843937e-01 | 0.053 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 8.843937e-01 | 0.053 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 8.843937e-01 | 0.053 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 8.843937e-01 | 0.053 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 8.843937e-01 | 0.053 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 8.843937e-01 | 0.053 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 8.853827e-01 | 0.053 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 8.861011e-01 | 0.053 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 8.866689e-01 | 0.052 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 8.867997e-01 | 0.052 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 8.867997e-01 | 0.052 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 8.867997e-01 | 0.052 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 8.912798e-01 | 0.050 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 8.933773e-01 | 0.049 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 8.933773e-01 | 0.049 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 8.933773e-01 | 0.049 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 8.942864e-01 | 0.049 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 8.948258e-01 | 0.048 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 8.948258e-01 | 0.048 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.948258e-01 | 0.048 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 8.948258e-01 | 0.048 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 8.948258e-01 | 0.048 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 8.960487e-01 | 0.048 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 8.964853e-01 | 0.047 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 8.968402e-01 | 0.047 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 8.968402e-01 | 0.047 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 8.968402e-01 | 0.047 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 8.968402e-01 | 0.047 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 8.968402e-01 | 0.047 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 8.968402e-01 | 0.047 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.968402e-01 | 0.047 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 8.968402e-01 | 0.047 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 8.968402e-01 | 0.047 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 8.968402e-01 | 0.047 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 8.968402e-01 | 0.047 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 8.968402e-01 | 0.047 | 0 | 0 |
| FASTK family proteins regulate processing and stability of mitochondrial RNAs | R-HSA-9837092 | 8.968402e-01 | 0.047 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 8.968402e-01 | 0.047 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 8.968402e-01 | 0.047 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 8.968402e-01 | 0.047 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 8.968402e-01 | 0.047 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 8.997279e-01 | 0.046 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.011420e-01 | 0.045 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 9.020469e-01 | 0.045 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 9.029294e-01 | 0.044 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.029294e-01 | 0.044 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 9.029294e-01 | 0.044 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.040078e-01 | 0.044 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 9.043760e-01 | 0.044 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 9.043760e-01 | 0.044 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 9.043760e-01 | 0.044 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.043760e-01 | 0.044 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 9.043760e-01 | 0.044 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 9.064834e-01 | 0.043 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 9.084712e-01 | 0.042 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 9.084712e-01 | 0.042 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 9.084712e-01 | 0.042 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 9.084712e-01 | 0.042 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 9.084712e-01 | 0.042 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 9.084712e-01 | 0.042 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 9.084712e-01 | 0.042 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 9.084712e-01 | 0.042 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 9.084712e-01 | 0.042 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 9.084712e-01 | 0.042 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 9.084712e-01 | 0.042 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 9.090252e-01 | 0.041 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 9.090252e-01 | 0.041 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 9.093879e-01 | 0.041 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 9.099179e-01 | 0.041 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 9.116929e-01 | 0.040 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 9.122210e-01 | 0.040 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 9.131103e-01 | 0.039 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.131103e-01 | 0.039 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 9.131103e-01 | 0.039 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 9.131103e-01 | 0.039 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.139801e-01 | 0.039 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.139801e-01 | 0.039 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 9.148899e-01 | 0.039 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 9.187515e-01 | 0.037 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 9.187915e-01 | 0.037 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 9.187915e-01 | 0.037 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 9.187915e-01 | 0.037 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 9.187915e-01 | 0.037 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 9.187915e-01 | 0.037 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 9.187915e-01 | 0.037 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 9.187915e-01 | 0.037 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 9.187915e-01 | 0.037 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 9.187915e-01 | 0.037 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 9.187915e-01 | 0.037 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 9.187915e-01 | 0.037 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 9.187915e-01 | 0.037 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 9.187915e-01 | 0.037 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 9.188145e-01 | 0.037 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 9.188145e-01 | 0.037 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 9.188145e-01 | 0.037 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 9.190175e-01 | 0.037 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.190175e-01 | 0.037 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 9.191777e-01 | 0.037 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 9.198314e-01 | 0.036 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 9.200921e-01 | 0.036 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 9.202278e-01 | 0.036 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 9.203609e-01 | 0.036 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.210915e-01 | 0.036 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 9.210915e-01 | 0.036 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 9.210915e-01 | 0.036 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.210915e-01 | 0.036 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.210915e-01 | 0.036 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 9.211482e-01 | 0.036 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.211482e-01 | 0.036 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 9.213291e-01 | 0.036 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 9.253625e-01 | 0.034 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.254079e-01 | 0.034 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.254079e-01 | 0.034 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 9.266769e-01 | 0.033 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 9.269171e-01 | 0.033 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 9.269904e-01 | 0.033 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 9.269904e-01 | 0.033 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 9.279486e-01 | 0.032 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 9.279486e-01 | 0.032 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.279486e-01 | 0.032 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 9.279486e-01 | 0.032 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 9.279486e-01 | 0.032 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 9.279486e-01 | 0.032 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 9.279486e-01 | 0.032 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 9.279486e-01 | 0.032 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.283782e-01 | 0.032 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.302043e-01 | 0.031 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 9.304872e-01 | 0.031 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 9.304872e-01 | 0.031 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 9.315066e-01 | 0.031 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 9.315066e-01 | 0.031 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 9.324394e-01 | 0.030 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 9.324394e-01 | 0.030 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 9.324394e-01 | 0.030 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 9.326477e-01 | 0.030 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.350255e-01 | 0.029 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 9.360737e-01 | 0.029 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 9.360737e-01 | 0.029 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 9.360737e-01 | 0.029 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 9.367969e-01 | 0.028 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 9.369562e-01 | 0.028 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.371430e-01 | 0.028 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.371430e-01 | 0.028 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.371430e-01 | 0.028 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.375175e-01 | 0.028 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 9.410849e-01 | 0.026 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 9.422461e-01 | 0.026 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.423479e-01 | 0.026 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 9.423479e-01 | 0.026 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 9.431039e-01 | 0.025 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.431039e-01 | 0.025 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 9.432829e-01 | 0.025 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 9.432829e-01 | 0.025 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.432829e-01 | 0.025 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 9.432829e-01 | 0.025 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 9.432829e-01 | 0.025 | 0 | 0 |
| HDL remodeling | R-HSA-8964058 | 9.432829e-01 | 0.025 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 9.432829e-01 | 0.025 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.432829e-01 | 0.025 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 9.440285e-01 | 0.025 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 9.455962e-01 | 0.024 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 9.456328e-01 | 0.024 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.461727e-01 | 0.024 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 9.466044e-01 | 0.024 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 9.466044e-01 | 0.024 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 9.466044e-01 | 0.024 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 9.466044e-01 | 0.024 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 9.466459e-01 | 0.024 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 9.466459e-01 | 0.024 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.471504e-01 | 0.024 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 9.477896e-01 | 0.023 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 9.480803e-01 | 0.023 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 9.496795e-01 | 0.022 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 9.496795e-01 | 0.022 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.496795e-01 | 0.022 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 9.496795e-01 | 0.022 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 9.496795e-01 | 0.022 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 9.496795e-01 | 0.022 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 9.496795e-01 | 0.022 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 9.504751e-01 | 0.022 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.515783e-01 | 0.022 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 9.515783e-01 | 0.022 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 9.515783e-01 | 0.022 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 9.515783e-01 | 0.022 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 9.515783e-01 | 0.022 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.515783e-01 | 0.022 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 9.515783e-01 | 0.022 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 9.516288e-01 | 0.022 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.516288e-01 | 0.022 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 9.516288e-01 | 0.022 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 9.552682e-01 | 0.020 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 9.553550e-01 | 0.020 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 9.553550e-01 | 0.020 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 9.553550e-01 | 0.020 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.556579e-01 | 0.020 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 9.561995e-01 | 0.019 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 9.561995e-01 | 0.019 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 9.561995e-01 | 0.019 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.561995e-01 | 0.019 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.561995e-01 | 0.019 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.580660e-01 | 0.019 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.580660e-01 | 0.019 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 9.585106e-01 | 0.018 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 9.590530e-01 | 0.018 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.594138e-01 | 0.018 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.594138e-01 | 0.018 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.599253e-01 | 0.018 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.603548e-01 | 0.018 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.603548e-01 | 0.018 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.603548e-01 | 0.018 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 9.603548e-01 | 0.018 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 9.603907e-01 | 0.018 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 9.603907e-01 | 0.018 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 9.603907e-01 | 0.018 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.603907e-01 | 0.018 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 9.603907e-01 | 0.018 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 9.603907e-01 | 0.018 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.613398e-01 | 0.017 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 9.628694e-01 | 0.016 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 9.640349e-01 | 0.016 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 9.641303e-01 | 0.016 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 9.641303e-01 | 0.016 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 9.643752e-01 | 0.016 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 9.643752e-01 | 0.016 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 9.648586e-01 | 0.016 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 9.648586e-01 | 0.016 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.648586e-01 | 0.016 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 9.648586e-01 | 0.016 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 9.648586e-01 | 0.016 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 9.648586e-01 | 0.016 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.648586e-01 | 0.016 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 9.648586e-01 | 0.016 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 9.652812e-01 | 0.015 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 9.662467e-01 | 0.015 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.671878e-01 | 0.014 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 9.675588e-01 | 0.014 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 9.675588e-01 | 0.014 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.675588e-01 | 0.014 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.686239e-01 | 0.014 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.688228e-01 | 0.014 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 9.688228e-01 | 0.014 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.688228e-01 | 0.014 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.688228e-01 | 0.014 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.688228e-01 | 0.014 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.688228e-01 | 0.014 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 9.688228e-01 | 0.014 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 9.689660e-01 | 0.014 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 9.699746e-01 | 0.013 | 0 | 0 |
| Depurination | R-HSA-73927 | 9.706706e-01 | 0.013 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 9.706706e-01 | 0.013 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 9.710335e-01 | 0.013 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 9.710335e-01 | 0.013 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.716469e-01 | 0.012 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 9.717193e-01 | 0.012 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 9.720957e-01 | 0.012 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.723400e-01 | 0.012 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.723400e-01 | 0.012 | 0 | 0 |
| Synthesis of dolichyl-phosphate | R-HSA-446199 | 9.723400e-01 | 0.012 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.723400e-01 | 0.012 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.723400e-01 | 0.012 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.734933e-01 | 0.012 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.741073e-01 | 0.011 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 9.741073e-01 | 0.011 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 9.741073e-01 | 0.011 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.741376e-01 | 0.011 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 9.741811e-01 | 0.011 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.754606e-01 | 0.011 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.754606e-01 | 0.011 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.754606e-01 | 0.011 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.754606e-01 | 0.011 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.754606e-01 | 0.011 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.754606e-01 | 0.011 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.754606e-01 | 0.011 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 9.758142e-01 | 0.011 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 9.759256e-01 | 0.011 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 9.760527e-01 | 0.011 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 9.760527e-01 | 0.011 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 9.760527e-01 | 0.011 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 9.763640e-01 | 0.010 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.764919e-01 | 0.010 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 9.769305e-01 | 0.010 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.776576e-01 | 0.010 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 9.782293e-01 | 0.010 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 9.782293e-01 | 0.010 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.782293e-01 | 0.010 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 9.782293e-01 | 0.010 | 0 | 0 |
| Attachment of bacteria to epithelial cells | R-HSA-9638630 | 9.782293e-01 | 0.010 | 0 | 0 |
| Linoleic acid (LA) metabolism | R-HSA-2046105 | 9.782293e-01 | 0.010 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 9.782293e-01 | 0.010 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 9.783721e-01 | 0.009 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.783721e-01 | 0.009 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 9.783805e-01 | 0.009 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 9.783954e-01 | 0.009 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.783954e-01 | 0.009 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 9.784328e-01 | 0.009 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 9.793508e-01 | 0.009 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 9.796542e-01 | 0.009 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.801529e-01 | 0.009 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.804732e-01 | 0.009 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.804732e-01 | 0.009 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 9.804732e-01 | 0.009 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.804732e-01 | 0.009 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.804732e-01 | 0.009 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 9.806858e-01 | 0.008 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 9.806858e-01 | 0.008 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 9.806858e-01 | 0.008 | 0 | 0 |
| Cobalamin (Cbl) metabolism | R-HSA-9759218 | 9.806858e-01 | 0.008 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.806858e-01 | 0.008 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 9.806858e-01 | 0.008 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.806858e-01 | 0.008 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.806858e-01 | 0.008 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.806858e-01 | 0.008 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.806858e-01 | 0.008 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 9.807739e-01 | 0.008 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 9.820640e-01 | 0.008 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 9.820640e-01 | 0.008 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 9.820640e-01 | 0.008 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.820640e-01 | 0.008 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.823757e-01 | 0.008 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.823757e-01 | 0.008 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.828652e-01 | 0.008 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.828652e-01 | 0.008 | 0 | 0 |
| Iron assimilation using enterobactin | R-HSA-9638334 | 9.828652e-01 | 0.008 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 9.828652e-01 | 0.008 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 9.830481e-01 | 0.007 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.835401e-01 | 0.007 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 9.836161e-01 | 0.007 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.840976e-01 | 0.007 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.840976e-01 | 0.007 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 9.844728e-01 | 0.007 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 9.846970e-01 | 0.007 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.847988e-01 | 0.007 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.847988e-01 | 0.007 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.847988e-01 | 0.007 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 9.851062e-01 | 0.007 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 9.851062e-01 | 0.007 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.851062e-01 | 0.007 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.856554e-01 | 0.006 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.856554e-01 | 0.006 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.856554e-01 | 0.006 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 9.856554e-01 | 0.006 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.856554e-01 | 0.006 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 9.859204e-01 | 0.006 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 9.859204e-01 | 0.006 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.865143e-01 | 0.006 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.865143e-01 | 0.006 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.870643e-01 | 0.006 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.872703e-01 | 0.006 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 9.876422e-01 | 0.005 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.876500e-01 | 0.005 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 9.880363e-01 | 0.005 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 9.880363e-01 | 0.005 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.880363e-01 | 0.005 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.881680e-01 | 0.005 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 9.883380e-01 | 0.005 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.883380e-01 | 0.005 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.886944e-01 | 0.005 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 9.891592e-01 | 0.005 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 9.891592e-01 | 0.005 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.893866e-01 | 0.005 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.893866e-01 | 0.005 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 9.896152e-01 | 0.005 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 9.897731e-01 | 0.004 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.897731e-01 | 0.004 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.901291e-01 | 0.004 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.901291e-01 | 0.004 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.901291e-01 | 0.004 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.905290e-01 | 0.004 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 9.905350e-01 | 0.004 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 9.905846e-01 | 0.004 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.905846e-01 | 0.004 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.905846e-01 | 0.004 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 9.907724e-01 | 0.004 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.909089e-01 | 0.004 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 9.909632e-01 | 0.004 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 9.911354e-01 | 0.004 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 9.911776e-01 | 0.004 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 9.914681e-01 | 0.004 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 9.914681e-01 | 0.004 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.914681e-01 | 0.004 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 9.915422e-01 | 0.004 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.915785e-01 | 0.004 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.915785e-01 | 0.004 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.916474e-01 | 0.004 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.916474e-01 | 0.004 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 9.918047e-01 | 0.004 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 9.921884e-01 | 0.003 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 9.922852e-01 | 0.003 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 9.923120e-01 | 0.003 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.923863e-01 | 0.003 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.925903e-01 | 0.003 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 9.925903e-01 | 0.003 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.925903e-01 | 0.003 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 9.925903e-01 | 0.003 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.925903e-01 | 0.003 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.925903e-01 | 0.003 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.925903e-01 | 0.003 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 9.930812e-01 | 0.003 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 9.933107e-01 | 0.003 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.934268e-01 | 0.003 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.934268e-01 | 0.003 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 9.934268e-01 | 0.003 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.934268e-01 | 0.003 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.934268e-01 | 0.003 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.934539e-01 | 0.003 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.934539e-01 | 0.003 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.934539e-01 | 0.003 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.936535e-01 | 0.003 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 9.937716e-01 | 0.003 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.939850e-01 | 0.003 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 9.940533e-01 | 0.003 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 9.941689e-01 | 0.003 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 9.941689e-01 | 0.003 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 9.941689e-01 | 0.003 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.941689e-01 | 0.003 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.941976e-01 | 0.003 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.944416e-01 | 0.002 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.944748e-01 | 0.002 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 9.946022e-01 | 0.002 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 9.946053e-01 | 0.002 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 9.946340e-01 | 0.002 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 9.948273e-01 | 0.002 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.948273e-01 | 0.002 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.948273e-01 | 0.002 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.948273e-01 | 0.002 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.949404e-01 | 0.002 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 9.953281e-01 | 0.002 | 0 | 0 |
| tRNA processing in the mitochondrion | R-HSA-6785470 | 9.954113e-01 | 0.002 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.954113e-01 | 0.002 | 0 | 0 |
| Biofilm formation | R-HSA-9931953 | 9.954113e-01 | 0.002 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.954113e-01 | 0.002 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 9.954622e-01 | 0.002 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.956897e-01 | 0.002 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 9.958870e-01 | 0.002 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.959295e-01 | 0.002 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.959295e-01 | 0.002 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.959295e-01 | 0.002 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.959295e-01 | 0.002 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 9.963297e-01 | 0.002 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 9.963537e-01 | 0.002 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.963891e-01 | 0.002 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.963891e-01 | 0.002 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 9.963891e-01 | 0.002 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.963891e-01 | 0.002 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.965512e-01 | 0.002 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.967430e-01 | 0.001 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.967969e-01 | 0.001 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.967969e-01 | 0.001 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 9.969099e-01 | 0.001 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 9.969099e-01 | 0.001 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.969099e-01 | 0.001 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.969761e-01 | 0.001 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 9.970151e-01 | 0.001 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.970336e-01 | 0.001 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 9.970848e-01 | 0.001 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 9.971128e-01 | 0.001 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.971587e-01 | 0.001 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.973339e-01 | 0.001 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 9.973580e-01 | 0.001 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.974389e-01 | 0.001 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.974796e-01 | 0.001 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.974796e-01 | 0.001 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.976043e-01 | 0.001 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 9.977440e-01 | 0.001 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.977643e-01 | 0.001 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.978315e-01 | 0.001 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.978315e-01 | 0.001 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.979667e-01 | 0.001 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 9.980168e-01 | 0.001 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.980168e-01 | 0.001 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.980168e-01 | 0.001 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.982409e-01 | 0.001 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.983543e-01 | 0.001 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 9.984284e-01 | 0.001 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.984396e-01 | 0.001 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.984396e-01 | 0.001 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 9.986159e-01 | 0.001 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.986159e-01 | 0.001 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.986336e-01 | 0.001 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 9.986673e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.987431e-01 | 0.001 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 9.987723e-01 | 0.001 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.987723e-01 | 0.001 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.987723e-01 | 0.001 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.988072e-01 | 0.001 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 9.988718e-01 | 0.000 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.989110e-01 | 0.000 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.989110e-01 | 0.000 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 9.989844e-01 | 0.000 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.989962e-01 | 0.000 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.990341e-01 | 0.000 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.990915e-01 | 0.000 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.991432e-01 | 0.000 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.991432e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.991849e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.991849e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.991849e-01 | 0.000 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 9.992025e-01 | 0.000 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 9.992400e-01 | 0.000 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 9.993259e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.993442e-01 | 0.000 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 9.993772e-01 | 0.000 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 9.994021e-01 | 0.000 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.994257e-01 | 0.000 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 9.994476e-01 | 0.000 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 9.994476e-01 | 0.000 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.994664e-01 | 0.000 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.994697e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.994697e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.994726e-01 | 0.000 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.994726e-01 | 0.000 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 9.995003e-01 | 0.000 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 9.995199e-01 | 0.000 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 9.995716e-01 | 0.000 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.995828e-01 | 0.000 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.995828e-01 | 0.000 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 9.995925e-01 | 0.000 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.996200e-01 | 0.000 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 9.996507e-01 | 0.000 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 9.996507e-01 | 0.000 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.996507e-01 | 0.000 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 9.996811e-01 | 0.000 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.997089e-01 | 0.000 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.997089e-01 | 0.000 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.997089e-01 | 0.000 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.997089e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.997265e-01 | 0.000 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.997265e-01 | 0.000 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 9.997852e-01 | 0.000 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.997887e-01 | 0.000 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 9.997903e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.997969e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.998199e-01 | 0.000 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.998552e-01 | 0.000 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.998566e-01 | 0.000 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.998735e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.998743e-01 | 0.000 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.998743e-01 | 0.000 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 9.998868e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.998868e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.998873e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.998886e-01 | 0.000 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.998972e-01 | 0.000 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.998987e-01 | 0.000 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 9.999188e-01 | 0.000 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.999223e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.999223e-01 | 0.000 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 9.999253e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999264e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.999311e-01 | 0.000 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.999350e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999369e-01 | 0.000 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.999479e-01 | 0.000 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 9.999583e-01 | 0.000 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 9.999583e-01 | 0.000 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.999627e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999665e-01 | 0.000 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.999678e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.999703e-01 | 0.000 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.999766e-01 | 0.000 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.999766e-01 | 0.000 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 9.999787e-01 | 0.000 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 9.999830e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999834e-01 | 0.000 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 9.999835e-01 | 0.000 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.999852e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.999886e-01 | 0.000 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 9.999902e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999922e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999938e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999940e-01 | 0.000 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 9.999960e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999962e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.999962e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999969e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.999973e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999973e-01 | 0.000 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 9.999973e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.999975e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999979e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999981e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999984e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.999992e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999996e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999996e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999996e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.999996e-01 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 9.999998e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999998e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.999999e-01 | 0.000 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.999999e-01 | 0.000 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 9.999999e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999999e-01 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 1.000000e+00 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 1.000000e+00 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 1.000000e+00 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 1.000000e+00 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 1.000000e+00 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 1.000000e+00 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 1.000000e+00 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 1.000000e+00 | 0.000 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 1.000000e+00 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle, Mitotic | R-HSA-69278 | 1.207989e-11 | 10.918 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.992717e-11 | 10.701 | 0 | 0 |
| M Phase | R-HSA-68886 | 8.983129e-09 | 8.047 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.239592e-06 | 5.907 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.622056e-06 | 5.790 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 2.879407e-06 | 5.541 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 1.268486e-05 | 4.897 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.213044e-05 | 4.916 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 1.391296e-05 | 4.857 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 2.212184e-05 | 4.655 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 2.474973e-05 | 4.606 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 2.699789e-05 | 4.569 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.853528e-05 | 4.545 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.975834e-05 | 4.526 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 3.520254e-05 | 4.453 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 3.652907e-05 | 4.437 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 6.672797e-05 | 4.176 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 6.730856e-05 | 4.172 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 7.048206e-05 | 4.152 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 8.911852e-05 | 4.050 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 8.326312e-05 | 4.080 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 8.622777e-05 | 4.064 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.027254e-04 | 3.988 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.093738e-04 | 3.961 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.663616e-04 | 3.779 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.682976e-04 | 3.774 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.782135e-04 | 3.749 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.977678e-04 | 3.704 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 2.333884e-04 | 3.632 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 2.538741e-04 | 3.595 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 2.622708e-04 | 3.581 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.577474e-04 | 3.446 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 3.757376e-04 | 3.425 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 3.909144e-04 | 3.408 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 3.836395e-04 | 3.416 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 5.016184e-04 | 3.300 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 5.113057e-04 | 3.291 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 5.335764e-04 | 3.273 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 6.035459e-04 | 3.219 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 6.043693e-04 | 3.219 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 6.484650e-04 | 3.188 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 6.305052e-04 | 3.200 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 7.427152e-04 | 3.129 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 7.427152e-04 | 3.129 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 7.296760e-04 | 3.137 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 7.296760e-04 | 3.137 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 7.979820e-04 | 3.098 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 8.378457e-04 | 3.077 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 8.719169e-04 | 3.060 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.097939e-03 | 2.959 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 1.052309e-03 | 2.978 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 1.013498e-03 | 2.994 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 1.070177e-03 | 2.971 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.052309e-03 | 2.978 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 1.104374e-03 | 2.957 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.298742e-03 | 2.886 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.279755e-03 | 2.893 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.306897e-03 | 2.884 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.386641e-03 | 2.858 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 1.321696e-03 | 2.879 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.547758e-03 | 2.810 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 1.581229e-03 | 2.801 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.757286e-03 | 2.755 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.735897e-03 | 2.760 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 1.757286e-03 | 2.755 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.784831e-03 | 2.748 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.829672e-03 | 2.738 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 1.880608e-03 | 2.726 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 1.976189e-03 | 2.704 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.976373e-03 | 2.704 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 2.104366e-03 | 2.677 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 2.258669e-03 | 2.646 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 2.151208e-03 | 2.667 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 2.300376e-03 | 2.638 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 2.300376e-03 | 2.638 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 2.402274e-03 | 2.619 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 2.607413e-03 | 2.584 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 2.607413e-03 | 2.584 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 2.480267e-03 | 2.606 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 2.616414e-03 | 2.582 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 2.617856e-03 | 2.582 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 2.827861e-03 | 2.549 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.854429e-03 | 2.544 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.854429e-03 | 2.544 | 0 | 0 |
| Kinesins | R-HSA-983189 | 2.928764e-03 | 2.533 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 3.062179e-03 | 2.514 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 3.683111e-03 | 2.434 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 3.681615e-03 | 2.434 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 3.681615e-03 | 2.434 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 3.431791e-03 | 2.464 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 3.683111e-03 | 2.434 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 3.669845e-03 | 2.435 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 3.598325e-03 | 2.444 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 3.710130e-03 | 2.431 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 3.739512e-03 | 2.427 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 3.878066e-03 | 2.411 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 4.218669e-03 | 2.375 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 4.014436e-03 | 2.396 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 4.055201e-03 | 2.392 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 4.134409e-03 | 2.384 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 4.134409e-03 | 2.384 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 4.276526e-03 | 2.369 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 4.468813e-03 | 2.350 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 4.712190e-03 | 2.327 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 4.771465e-03 | 2.321 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 4.771465e-03 | 2.321 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 4.772668e-03 | 2.321 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 4.825767e-03 | 2.316 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 4.825767e-03 | 2.316 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 4.963952e-03 | 2.304 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 5.429885e-03 | 2.265 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 5.422640e-03 | 2.266 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 5.521147e-03 | 2.258 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 5.540725e-03 | 2.256 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.555700e-03 | 2.255 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 5.747473e-03 | 2.241 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 6.038324e-03 | 2.219 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 6.092609e-03 | 2.215 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 6.160028e-03 | 2.210 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 6.233512e-03 | 2.205 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 6.269612e-03 | 2.203 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 7.647887e-03 | 2.116 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 7.009883e-03 | 2.154 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 7.975502e-03 | 2.098 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 7.975502e-03 | 2.098 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 8.042930e-03 | 2.095 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 8.042930e-03 | 2.095 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 8.076115e-03 | 2.093 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 8.123868e-03 | 2.090 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 8.123868e-03 | 2.090 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 8.601206e-03 | 2.065 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 8.958521e-03 | 2.048 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 9.192426e-03 | 2.037 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 8.471027e-03 | 2.072 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 8.917659e-03 | 2.050 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 9.407174e-03 | 2.027 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 9.088649e-03 | 2.042 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 9.434008e-03 | 2.025 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 9.623200e-03 | 2.017 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.071868e-02 | 1.970 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.071868e-02 | 1.970 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.071868e-02 | 1.970 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.071868e-02 | 1.970 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.071868e-02 | 1.970 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.071868e-02 | 1.970 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.071868e-02 | 1.970 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.100005e-02 | 1.959 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 9.954156e-03 | 2.002 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.042178e-02 | 1.982 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.042178e-02 | 1.982 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 1.054228e-02 | 1.977 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 1.083454e-02 | 1.965 | 1 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 9.801549e-03 | 2.009 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 1.100005e-02 | 1.959 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.100005e-02 | 1.959 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.036524e-02 | 1.984 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.109702e-02 | 1.955 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 1.126600e-02 | 1.948 | 0 | 0 |
| S Phase | R-HSA-69242 | 1.155501e-02 | 1.937 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.167761e-02 | 1.933 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 1.167761e-02 | 1.933 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 1.167761e-02 | 1.933 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 1.192051e-02 | 1.924 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.192051e-02 | 1.924 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.192051e-02 | 1.924 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 1.197472e-02 | 1.922 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.233758e-02 | 1.909 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.270293e-02 | 1.896 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 1.467885e-02 | 1.833 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 1.467885e-02 | 1.833 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 1.398313e-02 | 1.854 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 1.397783e-02 | 1.855 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 1.323082e-02 | 1.878 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 1.427401e-02 | 1.845 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.388210e-02 | 1.858 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 1.467885e-02 | 1.833 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.369758e-02 | 1.863 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.446020e-02 | 1.840 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 1.299438e-02 | 1.886 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.304817e-02 | 1.884 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 1.526826e-02 | 1.816 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.560772e-02 | 1.807 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 1.655140e-02 | 1.781 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.681722e-02 | 1.774 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.687731e-02 | 1.773 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.687731e-02 | 1.773 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 1.694708e-02 | 1.771 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.753061e-02 | 1.756 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.753141e-02 | 1.756 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 1.755743e-02 | 1.756 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.905295e-02 | 1.720 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 1.905295e-02 | 1.720 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.907090e-02 | 1.720 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.993389e-02 | 1.700 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 2.018093e-02 | 1.695 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 2.143454e-02 | 1.669 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 2.193664e-02 | 1.659 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 1.955984e-02 | 1.709 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 2.034347e-02 | 1.692 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 2.169946e-02 | 1.664 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 2.211219e-02 | 1.655 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 2.092037e-02 | 1.679 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.097225e-02 | 1.678 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.955984e-02 | 1.709 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 2.242901e-02 | 1.649 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 2.258986e-02 | 1.646 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.261138e-02 | 1.646 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 2.293010e-02 | 1.640 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 2.293010e-02 | 1.640 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 2.377017e-02 | 1.624 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 2.381232e-02 | 1.623 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 2.462239e-02 | 1.609 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 2.474455e-02 | 1.607 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.474455e-02 | 1.607 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 2.556408e-02 | 1.592 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 2.579743e-02 | 1.588 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.634894e-02 | 1.579 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.634894e-02 | 1.579 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.634894e-02 | 1.579 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.634894e-02 | 1.579 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 2.641093e-02 | 1.578 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 2.648503e-02 | 1.577 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 2.677636e-02 | 1.572 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 2.677636e-02 | 1.572 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 2.691858e-02 | 1.570 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 2.691858e-02 | 1.570 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 3.048849e-02 | 1.516 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 2.871641e-02 | 1.542 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 3.022589e-02 | 1.520 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 3.358087e-02 | 1.474 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 3.358087e-02 | 1.474 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 2.986328e-02 | 1.525 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 2.986328e-02 | 1.525 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 3.126006e-02 | 1.505 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 3.000798e-02 | 1.523 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 3.270190e-02 | 1.485 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 3.167713e-02 | 1.499 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 3.187275e-02 | 1.497 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 2.979306e-02 | 1.526 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 3.000798e-02 | 1.523 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 3.229847e-02 | 1.491 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 3.360716e-02 | 1.474 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 3.022589e-02 | 1.520 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 3.360716e-02 | 1.474 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 3.263442e-02 | 1.486 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 3.434237e-02 | 1.464 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 3.475862e-02 | 1.459 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 3.486817e-02 | 1.458 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 3.497381e-02 | 1.456 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 3.765080e-02 | 1.424 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 3.782171e-02 | 1.422 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 3.782171e-02 | 1.422 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 3.785746e-02 | 1.422 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 3.785746e-02 | 1.422 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 3.866912e-02 | 1.413 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.866912e-02 | 1.413 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 3.957462e-02 | 1.403 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 3.963374e-02 | 1.402 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 4.061445e-02 | 1.391 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 4.106628e-02 | 1.387 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 4.150049e-02 | 1.382 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 4.324534e-02 | 1.364 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 4.364324e-02 | 1.360 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 4.402265e-02 | 1.356 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 4.402265e-02 | 1.356 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 4.468021e-02 | 1.350 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.605705e-02 | 1.337 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 4.614387e-02 | 1.336 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 4.623674e-02 | 1.335 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 4.663232e-02 | 1.331 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 4.675457e-02 | 1.330 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 4.706023e-02 | 1.327 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 4.768775e-02 | 1.322 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 4.811537e-02 | 1.318 | 0 | 0 |
| Signaling by FGFR1 amplification mutants | R-HSA-1839120 | 5.763782e-02 | 1.239 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 5.763782e-02 | 1.239 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 5.763782e-02 | 1.239 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 5.446820e-02 | 1.264 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 5.446820e-02 | 1.264 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 5.446820e-02 | 1.264 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 5.219147e-02 | 1.282 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 5.631598e-02 | 1.249 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 4.939174e-02 | 1.306 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 4.997604e-02 | 1.301 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 4.940464e-02 | 1.306 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 5.228998e-02 | 1.282 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 5.219147e-02 | 1.282 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 5.763782e-02 | 1.239 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 4.939174e-02 | 1.306 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 5.733727e-02 | 1.242 | 1 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 6.071566e-02 | 1.217 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 5.109877e-02 | 1.292 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 5.128893e-02 | 1.290 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 5.296603e-02 | 1.276 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 6.112762e-02 | 1.214 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 6.164055e-02 | 1.210 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 6.258131e-02 | 1.204 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 6.454295e-02 | 1.190 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 6.486868e-02 | 1.188 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 6.486868e-02 | 1.188 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 6.629639e-02 | 1.179 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 6.629639e-02 | 1.179 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 6.693343e-02 | 1.174 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 6.693343e-02 | 1.174 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 6.693343e-02 | 1.174 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 6.853814e-02 | 1.164 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 6.946441e-02 | 1.158 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 7.081774e-02 | 1.150 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 7.081774e-02 | 1.150 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 7.184206e-02 | 1.144 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 7.283474e-02 | 1.138 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 7.417383e-02 | 1.130 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 7.482284e-02 | 1.126 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 7.482284e-02 | 1.126 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 7.615036e-02 | 1.118 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 7.899412e-02 | 1.102 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 7.899412e-02 | 1.102 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 7.899412e-02 | 1.102 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 7.899412e-02 | 1.102 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 7.899412e-02 | 1.102 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 7.936521e-02 | 1.100 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 8.057009e-02 | 1.094 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 8.057009e-02 | 1.094 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 8.088664e-02 | 1.092 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 8.088664e-02 | 1.092 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 8.423771e-02 | 1.074 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 8.423771e-02 | 1.074 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 8.763202e-02 | 1.057 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 8.767558e-02 | 1.057 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 8.837339e-02 | 1.054 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 8.961793e-02 | 1.048 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 9.189008e-02 | 1.037 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 9.244988e-02 | 1.034 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 9.344564e-02 | 1.029 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 9.430807e-02 | 1.025 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 9.430807e-02 | 1.025 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 9.529796e-02 | 1.021 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 9.563529e-02 | 1.019 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.023678e-01 | 0.990 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 1.023678e-01 | 0.990 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 1.023678e-01 | 0.990 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 1.273425e-01 | 0.895 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.273425e-01 | 0.895 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 1.110303e-01 | 0.955 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 1.276760e-01 | 0.894 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 1.276760e-01 | 0.894 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 1.276760e-01 | 0.894 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.276760e-01 | 0.894 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 1.166643e-01 | 0.933 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 1.166643e-01 | 0.933 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 1.144617e-01 | 0.941 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.036655e-01 | 0.984 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 1.045313e-01 | 0.981 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 1.045313e-01 | 0.981 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.052858e-01 | 0.978 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 1.276760e-01 | 0.894 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.136803e-01 | 0.944 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 1.276760e-01 | 0.894 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 1.276760e-01 | 0.894 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.193222e-01 | 0.923 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.041426e-01 | 0.982 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 1.041426e-01 | 0.982 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.041426e-01 | 0.982 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.014503e-01 | 0.994 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.276760e-01 | 0.894 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 1.148426e-01 | 0.940 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.255250e-01 | 0.901 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.027899e-01 | 0.988 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.027899e-01 | 0.988 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 1.276760e-01 | 0.894 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 9.645825e-02 | 1.016 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.067959e-01 | 0.971 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 1.093765e-01 | 0.961 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 9.675817e-02 | 1.014 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 1.259734e-01 | 0.900 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 1.273425e-01 | 0.895 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 1.273425e-01 | 0.895 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.185224e-01 | 0.926 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.055041e-01 | 0.977 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 9.622987e-02 | 1.017 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.041966e-01 | 0.982 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.278333e-01 | 0.893 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 1.278333e-01 | 0.893 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 1.280357e-01 | 0.893 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.280357e-01 | 0.893 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 1.297462e-01 | 0.887 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 1.297462e-01 | 0.887 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.332699e-01 | 0.875 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 1.350128e-01 | 0.870 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.359232e-01 | 0.867 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 1.362066e-01 | 0.866 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 1.362066e-01 | 0.866 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 1.364833e-01 | 0.865 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.378601e-01 | 0.861 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.417218e-01 | 0.849 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 1.428500e-01 | 0.845 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.428500e-01 | 0.845 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 1.428500e-01 | 0.845 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 1.428500e-01 | 0.845 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.428500e-01 | 0.845 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.064357e-01 | 0.685 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.064357e-01 | 0.685 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 2.064357e-01 | 0.685 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 2.653079e-01 | 0.576 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 2.653079e-01 | 0.576 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 2.653079e-01 | 0.576 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 2.653079e-01 | 0.576 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 2.653079e-01 | 0.576 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 2.653079e-01 | 0.576 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 2.653079e-01 | 0.576 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 2.653079e-01 | 0.576 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 1.806781e-01 | 0.743 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 1.806781e-01 | 0.743 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 1.806781e-01 | 0.743 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 1.806781e-01 | 0.743 | 0 | 0 |
| Signaling by plasma membrane FGFR1 fusions | R-HSA-8853336 | 3.198159e-01 | 0.495 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 3.198159e-01 | 0.495 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 3.198159e-01 | 0.495 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 2.084390e-01 | 0.681 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 2.084390e-01 | 0.681 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 2.084390e-01 | 0.681 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 2.084390e-01 | 0.681 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 1.633339e-01 | 0.787 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 2.365921e-01 | 0.626 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 2.365921e-01 | 0.626 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 3.702828e-01 | 0.431 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 3.702828e-01 | 0.431 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 3.702828e-01 | 0.431 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 3.702828e-01 | 0.431 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 3.702828e-01 | 0.431 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 1.821585e-01 | 0.740 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 1.821585e-01 | 0.740 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 2.649267e-01 | 0.577 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 2.649267e-01 | 0.577 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 2.649267e-01 | 0.577 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 2.015239e-01 | 0.696 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 2.015239e-01 | 0.696 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 1.575971e-01 | 0.802 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 1.722837e-01 | 0.764 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 2.213411e-01 | 0.655 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 2.932612e-01 | 0.533 | 0 | 0 |
| FGFR1c and Klotho ligand binding and activation | R-HSA-190374 | 4.170081e-01 | 0.380 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 4.170081e-01 | 0.380 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.170081e-01 | 0.380 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.170081e-01 | 0.380 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 2.415240e-01 | 0.617 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.029643e-01 | 0.693 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 3.214398e-01 | 0.493 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 3.214398e-01 | 0.493 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 3.214398e-01 | 0.493 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 3.214398e-01 | 0.493 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 3.214398e-01 | 0.493 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 2.619904e-01 | 0.582 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 2.188704e-01 | 0.660 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 1.586601e-01 | 0.800 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 2.826623e-01 | 0.549 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 3.493298e-01 | 0.457 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 3.493298e-01 | 0.457 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 3.493298e-01 | 0.457 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 3.493298e-01 | 0.457 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 3.493298e-01 | 0.457 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 3.493298e-01 | 0.457 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 2.120620e-01 | 0.674 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 2.120620e-01 | 0.674 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 2.120620e-01 | 0.674 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.515939e-01 | 0.599 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.515939e-01 | 0.599 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 2.683248e-01 | 0.571 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.683248e-01 | 0.571 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 2.683248e-01 | 0.571 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.683248e-01 | 0.571 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.848121e-01 | 0.733 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 2.397704e-01 | 0.620 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 2.397704e-01 | 0.620 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 1.534179e-01 | 0.814 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 3.243329e-01 | 0.489 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 3.243329e-01 | 0.489 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 1.952017e-01 | 0.710 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.952017e-01 | 0.710 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 2.852451e-01 | 0.545 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 4.038135e-01 | 0.394 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 4.038135e-01 | 0.394 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 4.038135e-01 | 0.394 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 2.657545e-01 | 0.576 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 3.367398e-01 | 0.473 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 4.302354e-01 | 0.366 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 4.302354e-01 | 0.366 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 4.302354e-01 | 0.366 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 4.302354e-01 | 0.366 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 3.125367e-01 | 0.505 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 2.006141e-01 | 0.698 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 3.866921e-01 | 0.413 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 3.866921e-01 | 0.413 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 3.049613e-01 | 0.516 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 3.424880e-01 | 0.465 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 4.072156e-01 | 0.390 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.564656e-01 | 0.591 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 3.885485e-01 | 0.411 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 4.275279e-01 | 0.369 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 3.133847e-01 | 0.504 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 3.721291e-01 | 0.429 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 3.664505e-01 | 0.436 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 4.203298e-01 | 0.376 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 3.243329e-01 | 0.489 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 3.243329e-01 | 0.489 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 2.415240e-01 | 0.617 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 2.415240e-01 | 0.617 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 3.274776e-01 | 0.485 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 2.168297e-01 | 0.664 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 2.619904e-01 | 0.582 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 4.127534e-01 | 0.384 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 3.125367e-01 | 0.505 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 2.492665e-01 | 0.603 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 2.415240e-01 | 0.617 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 2.029643e-01 | 0.693 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 3.034661e-01 | 0.518 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 3.243329e-01 | 0.489 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 3.214398e-01 | 0.493 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 3.023140e-01 | 0.520 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 2.618224e-01 | 0.582 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 2.350948e-01 | 0.629 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 2.365921e-01 | 0.626 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.213411e-01 | 0.655 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.023140e-01 | 0.520 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.619904e-01 | 0.582 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 3.660030e-01 | 0.437 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 3.463769e-01 | 0.460 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 1.806781e-01 | 0.743 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 2.649267e-01 | 0.577 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.932612e-01 | 0.533 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 2.932612e-01 | 0.533 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 3.214398e-01 | 0.493 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 1.854736e-01 | 0.732 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 3.451983e-01 | 0.462 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 3.344448e-01 | 0.476 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 2.120620e-01 | 0.674 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 1.821585e-01 | 0.740 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 3.007946e-01 | 0.522 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 4.170081e-01 | 0.380 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 2.188704e-01 | 0.660 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 2.826623e-01 | 0.549 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 4.302354e-01 | 0.366 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 2.425200e-01 | 0.615 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 4.228130e-01 | 0.374 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 3.831706e-01 | 0.417 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 2.350948e-01 | 0.629 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 2.679425e-01 | 0.572 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 2.166438e-01 | 0.664 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 4.127534e-01 | 0.384 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 3.583225e-01 | 0.446 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 2.213411e-01 | 0.655 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 2.932612e-01 | 0.533 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 4.170081e-01 | 0.380 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 4.170081e-01 | 0.380 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 4.170081e-01 | 0.380 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.415240e-01 | 0.617 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 2.120620e-01 | 0.674 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 2.038255e-01 | 0.691 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 3.243329e-01 | 0.489 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 2.658161e-01 | 0.575 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 2.403780e-01 | 0.619 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 1.794436e-01 | 0.746 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 2.735171e-01 | 0.563 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 3.768190e-01 | 0.424 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 1.862888e-01 | 0.730 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 2.276714e-01 | 0.643 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 4.040937e-01 | 0.394 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 3.702828e-01 | 0.431 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 2.015239e-01 | 0.696 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 1.782784e-01 | 0.749 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 4.038135e-01 | 0.394 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 3.660030e-01 | 0.437 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 4.302354e-01 | 0.366 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 2.618224e-01 | 0.582 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 1.986145e-01 | 0.702 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 2.370112e-01 | 0.625 | 0 | 0 |
| Protein folding | R-HSA-391251 | 2.658161e-01 | 0.575 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 1.979159e-01 | 0.704 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 2.370112e-01 | 0.625 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 3.575438e-01 | 0.447 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 1.695179e-01 | 0.771 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 2.826623e-01 | 0.549 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 1.764600e-01 | 0.753 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 2.157837e-01 | 0.666 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 1.761110e-01 | 0.754 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 3.540217e-01 | 0.451 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 2.619904e-01 | 0.582 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.980552e-01 | 0.703 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 2.515939e-01 | 0.599 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 2.514979e-01 | 0.599 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.064357e-01 | 0.685 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.064357e-01 | 0.685 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 2.653079e-01 | 0.576 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 2.653079e-01 | 0.576 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 2.653079e-01 | 0.576 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 1.535528e-01 | 0.814 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 3.198159e-01 | 0.495 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 1.821585e-01 | 0.740 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.649267e-01 | 0.577 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 2.649267e-01 | 0.577 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 2.213411e-01 | 0.655 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 4.170081e-01 | 0.380 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 4.170081e-01 | 0.380 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 2.029643e-01 | 0.693 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 3.214398e-01 | 0.493 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.457362e-01 | 0.836 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 3.493298e-01 | 0.457 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 2.515939e-01 | 0.599 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 3.243329e-01 | 0.489 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 4.302354e-01 | 0.366 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 4.302354e-01 | 0.366 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 3.182608e-01 | 0.497 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 3.182608e-01 | 0.497 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 3.885485e-01 | 0.411 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 3.328620e-01 | 0.478 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 2.649267e-01 | 0.577 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.029643e-01 | 0.693 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.029643e-01 | 0.693 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 3.234441e-01 | 0.490 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 3.338470e-01 | 0.476 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 2.080107e-01 | 0.682 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 1.681513e-01 | 0.774 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.952017e-01 | 0.710 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.627862e-01 | 0.788 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 3.338470e-01 | 0.476 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 3.338470e-01 | 0.476 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 2.002934e-01 | 0.698 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 2.118915e-01 | 0.674 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 2.649267e-01 | 0.577 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 4.170081e-01 | 0.380 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 3.243329e-01 | 0.489 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 4.038135e-01 | 0.394 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 1.862888e-01 | 0.730 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 2.874119e-01 | 0.541 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 2.515939e-01 | 0.599 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 1.869485e-01 | 0.728 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 3.710082e-01 | 0.431 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 1.436320e-01 | 0.843 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 2.257895e-01 | 0.646 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 3.702828e-01 | 0.431 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 2.649267e-01 | 0.577 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 1.722837e-01 | 0.764 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.170081e-01 | 0.380 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 3.243329e-01 | 0.489 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 2.572288e-01 | 0.590 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 2.972909e-01 | 0.527 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 2.972909e-01 | 0.527 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 2.403780e-01 | 0.619 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 3.194916e-01 | 0.496 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.115452e-01 | 0.675 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 4.302354e-01 | 0.366 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 3.575438e-01 | 0.447 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 3.660030e-01 | 0.437 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.064357e-01 | 0.685 | 0 | 0 |
| Inhibition of membrane repair | R-HSA-9635644 | 2.064357e-01 | 0.685 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.198159e-01 | 0.495 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 1.451419e-01 | 0.838 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 1.821585e-01 | 0.740 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 2.213411e-01 | 0.655 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 3.451983e-01 | 0.462 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 1.695179e-01 | 0.771 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 4.202958e-01 | 0.376 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 4.263850e-01 | 0.370 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.157837e-01 | 0.666 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 2.168297e-01 | 0.664 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 1.806781e-01 | 0.743 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 3.538964e-01 | 0.451 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 3.034661e-01 | 0.518 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 4.072156e-01 | 0.390 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 2.786897e-01 | 0.555 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 2.279739e-01 | 0.642 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 2.715014e-01 | 0.566 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 3.023417e-01 | 0.520 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 3.226384e-01 | 0.491 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 3.198159e-01 | 0.495 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 1.575971e-01 | 0.802 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 3.214398e-01 | 0.493 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 1.854736e-01 | 0.732 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 2.829644e-01 | 0.548 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 4.079028e-01 | 0.389 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 4.126003e-01 | 0.384 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.921170e-01 | 0.716 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 2.578830e-01 | 0.589 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.854736e-01 | 0.732 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 3.660030e-01 | 0.437 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 3.619853e-01 | 0.441 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 2.095751e-01 | 0.679 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 3.660030e-01 | 0.437 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 4.302354e-01 | 0.366 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 4.302354e-01 | 0.366 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 3.866921e-01 | 0.413 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 1.576993e-01 | 0.802 | 1 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 2.649267e-01 | 0.577 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 3.768190e-01 | 0.424 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 2.397704e-01 | 0.620 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 4.072156e-01 | 0.390 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 2.932612e-01 | 0.533 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 3.572710e-01 | 0.447 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 3.995162e-01 | 0.398 | 1 | 0 |
| PECAM1 interactions | R-HSA-210990 | 2.932612e-01 | 0.533 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.362208e-01 | 0.627 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 3.866921e-01 | 0.413 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 3.872383e-01 | 0.412 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 3.493298e-01 | 0.457 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 3.940226e-01 | 0.404 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 2.276714e-01 | 0.643 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 2.188704e-01 | 0.660 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 3.108092e-01 | 0.508 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 2.649267e-01 | 0.577 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 3.768190e-01 | 0.424 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 4.038135e-01 | 0.394 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 4.311114e-01 | 0.365 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 4.397740e-01 | 0.357 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 4.397740e-01 | 0.357 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 4.426413e-01 | 0.354 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 4.475880e-01 | 0.349 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 4.475880e-01 | 0.349 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 4.475880e-01 | 0.349 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 4.475880e-01 | 0.349 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 4.483131e-01 | 0.348 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 4.483131e-01 | 0.348 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 4.530911e-01 | 0.344 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 4.530911e-01 | 0.344 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 4.560212e-01 | 0.341 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 4.560212e-01 | 0.341 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.560212e-01 | 0.341 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 4.560212e-01 | 0.341 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 4.560212e-01 | 0.341 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 4.565858e-01 | 0.340 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 4.572800e-01 | 0.340 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 4.602689e-01 | 0.337 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 4.602689e-01 | 0.337 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 4.602689e-01 | 0.337 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 4.602689e-01 | 0.337 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 4.602689e-01 | 0.337 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 4.602689e-01 | 0.337 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 4.602689e-01 | 0.337 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 4.602689e-01 | 0.337 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 4.633265e-01 | 0.334 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 4.673588e-01 | 0.330 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 4.673588e-01 | 0.330 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 4.673588e-01 | 0.330 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.732243e-01 | 0.325 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 4.732243e-01 | 0.325 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 4.732243e-01 | 0.325 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 4.739969e-01 | 0.324 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 4.771680e-01 | 0.321 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 4.771680e-01 | 0.321 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 4.811198e-01 | 0.318 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 4.811198e-01 | 0.318 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 4.811198e-01 | 0.318 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 4.811198e-01 | 0.318 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 4.811198e-01 | 0.318 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 4.811198e-01 | 0.318 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 4.811198e-01 | 0.318 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 4.811198e-01 | 0.318 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 4.896674e-01 | 0.310 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 4.896674e-01 | 0.310 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 4.896674e-01 | 0.310 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 4.896674e-01 | 0.310 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 4.896674e-01 | 0.310 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 4.896674e-01 | 0.310 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 4.896674e-01 | 0.310 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 4.901930e-01 | 0.310 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 4.945350e-01 | 0.306 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 4.951933e-01 | 0.305 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 4.996674e-01 | 0.301 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 5.003220e-01 | 0.301 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.003220e-01 | 0.301 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 5.003220e-01 | 0.301 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 5.003220e-01 | 0.301 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 5.003220e-01 | 0.301 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 5.003220e-01 | 0.301 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 5.003220e-01 | 0.301 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 5.054913e-01 | 0.296 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 5.054913e-01 | 0.296 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 5.054913e-01 | 0.296 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 5.054913e-01 | 0.296 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 5.054913e-01 | 0.296 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 5.054913e-01 | 0.296 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 5.057093e-01 | 0.296 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 5.058313e-01 | 0.296 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 5.058948e-01 | 0.296 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 5.058948e-01 | 0.296 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 5.058948e-01 | 0.296 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 5.059056e-01 | 0.296 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 5.059056e-01 | 0.296 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 5.059056e-01 | 0.296 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 5.126058e-01 | 0.290 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 5.161533e-01 | 0.287 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 5.176321e-01 | 0.286 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 5.246274e-01 | 0.280 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 5.246274e-01 | 0.280 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 5.246274e-01 | 0.280 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 5.291053e-01 | 0.276 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 5.291053e-01 | 0.276 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 5.291053e-01 | 0.276 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 5.291053e-01 | 0.276 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 5.291053e-01 | 0.276 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 5.291053e-01 | 0.276 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 5.291053e-01 | 0.276 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 5.291053e-01 | 0.276 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 5.326570e-01 | 0.274 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 5.337992e-01 | 0.273 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 5.359941e-01 | 0.271 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 5.364981e-01 | 0.270 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 5.374050e-01 | 0.270 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 5.374050e-01 | 0.270 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 5.374050e-01 | 0.270 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 5.374050e-01 | 0.270 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 5.374050e-01 | 0.270 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 5.374050e-01 | 0.270 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 5.374050e-01 | 0.270 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 5.374050e-01 | 0.270 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 5.374050e-01 | 0.270 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 5.374050e-01 | 0.270 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 5.374050e-01 | 0.270 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 5.374050e-01 | 0.270 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 5.374050e-01 | 0.270 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 5.374050e-01 | 0.270 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 5.374050e-01 | 0.270 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 5.374050e-01 | 0.270 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 5.374050e-01 | 0.270 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 5.374050e-01 | 0.270 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 5.374050e-01 | 0.270 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 5.374050e-01 | 0.270 | 0 | 0 |
| Maturation of replicase proteins | R-HSA-9694301 | 5.374050e-01 | 0.270 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 5.429511e-01 | 0.265 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 5.478692e-01 | 0.261 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 5.486238e-01 | 0.261 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 5.519401e-01 | 0.258 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 5.519401e-01 | 0.258 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 5.519401e-01 | 0.258 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 5.519401e-01 | 0.258 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 5.519401e-01 | 0.258 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 5.531059e-01 | 0.257 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 5.565078e-01 | 0.255 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 5.566339e-01 | 0.254 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 5.571690e-01 | 0.254 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 5.589631e-01 | 0.253 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 5.597359e-01 | 0.252 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 5.608584e-01 | 0.251 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 5.614085e-01 | 0.251 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 5.614972e-01 | 0.251 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 5.640863e-01 | 0.249 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 5.683022e-01 | 0.245 | 0 | 0 |
| RSK activation | R-HSA-444257 | 5.717379e-01 | 0.243 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 5.717379e-01 | 0.243 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 5.717379e-01 | 0.243 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 5.717379e-01 | 0.243 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 5.717379e-01 | 0.243 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 5.717379e-01 | 0.243 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 5.717379e-01 | 0.243 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 5.717379e-01 | 0.243 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 5.717379e-01 | 0.243 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 5.717379e-01 | 0.243 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 5.717379e-01 | 0.243 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 5.717379e-01 | 0.243 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 5.717379e-01 | 0.243 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 5.717379e-01 | 0.243 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 5.717379e-01 | 0.243 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 5.717379e-01 | 0.243 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 5.717379e-01 | 0.243 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 5.739813e-01 | 0.241 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 5.739813e-01 | 0.241 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 5.739813e-01 | 0.241 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 5.783336e-01 | 0.238 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 5.783336e-01 | 0.238 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 5.809472e-01 | 0.236 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 5.832069e-01 | 0.234 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 5.832069e-01 | 0.234 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 5.832069e-01 | 0.234 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 5.901163e-01 | 0.229 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 5.950310e-01 | 0.225 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 5.952208e-01 | 0.225 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 5.952208e-01 | 0.225 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 5.953641e-01 | 0.225 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 5.953641e-01 | 0.225 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 5.953641e-01 | 0.225 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 5.971169e-01 | 0.224 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 5.978098e-01 | 0.223 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 6.035246e-01 | 0.219 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 6.035246e-01 | 0.219 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 6.035246e-01 | 0.219 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 6.035246e-01 | 0.219 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 6.035246e-01 | 0.219 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 6.035246e-01 | 0.219 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 6.035246e-01 | 0.219 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 6.035246e-01 | 0.219 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 6.035246e-01 | 0.219 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 6.035246e-01 | 0.219 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.035246e-01 | 0.219 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 6.035246e-01 | 0.219 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 6.035246e-01 | 0.219 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 6.035246e-01 | 0.219 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 6.035246e-01 | 0.219 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 6.035246e-01 | 0.219 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 6.035246e-01 | 0.219 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 6.035246e-01 | 0.219 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 6.046848e-01 | 0.218 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 6.046848e-01 | 0.218 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 6.104553e-01 | 0.214 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 6.105127e-01 | 0.214 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 6.119399e-01 | 0.213 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 6.121019e-01 | 0.213 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 6.121019e-01 | 0.213 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 6.138230e-01 | 0.212 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 6.154419e-01 | 0.211 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 6.162743e-01 | 0.210 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 6.257168e-01 | 0.204 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 6.260755e-01 | 0.203 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 6.260755e-01 | 0.203 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 6.276702e-01 | 0.202 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 6.280534e-01 | 0.202 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 6.280534e-01 | 0.202 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 6.280534e-01 | 0.202 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 6.292474e-01 | 0.201 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 6.329538e-01 | 0.199 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 6.329538e-01 | 0.199 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 6.329538e-01 | 0.199 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 6.329538e-01 | 0.199 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 6.329538e-01 | 0.199 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 6.329538e-01 | 0.199 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 6.329538e-01 | 0.199 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 6.352902e-01 | 0.197 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 6.352902e-01 | 0.197 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 6.352902e-01 | 0.197 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 6.370719e-01 | 0.196 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 6.370719e-01 | 0.196 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 6.370719e-01 | 0.196 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 6.385681e-01 | 0.195 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 6.385681e-01 | 0.195 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 6.397245e-01 | 0.194 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 6.397245e-01 | 0.194 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 6.397245e-01 | 0.194 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 6.436992e-01 | 0.191 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 6.436992e-01 | 0.191 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 6.436992e-01 | 0.191 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 6.436992e-01 | 0.191 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 6.480049e-01 | 0.188 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 6.487157e-01 | 0.188 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 6.501963e-01 | 0.187 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 6.505657e-01 | 0.187 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 6.505657e-01 | 0.187 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 6.506853e-01 | 0.187 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 6.530437e-01 | 0.185 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 6.530437e-01 | 0.185 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 6.541287e-01 | 0.184 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 6.541287e-01 | 0.184 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 6.541287e-01 | 0.184 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 6.541287e-01 | 0.184 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 6.542625e-01 | 0.184 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 6.542625e-01 | 0.184 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 6.581478e-01 | 0.182 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 6.588739e-01 | 0.181 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 6.602002e-01 | 0.180 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 6.602002e-01 | 0.180 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 6.602002e-01 | 0.180 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 6.602002e-01 | 0.180 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 6.602002e-01 | 0.180 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 6.602002e-01 | 0.180 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 6.602002e-01 | 0.180 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 6.623075e-01 | 0.179 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 6.641677e-01 | 0.178 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 6.641677e-01 | 0.178 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 6.641677e-01 | 0.178 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 6.660293e-01 | 0.177 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 6.660293e-01 | 0.177 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 6.698264e-01 | 0.174 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 6.698264e-01 | 0.174 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 6.719747e-01 | 0.173 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 6.721818e-01 | 0.173 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 6.721818e-01 | 0.173 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 6.721818e-01 | 0.173 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 6.721818e-01 | 0.173 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 6.786784e-01 | 0.168 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 6.786784e-01 | 0.168 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 6.787975e-01 | 0.168 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 6.854256e-01 | 0.164 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 6.854256e-01 | 0.164 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 6.854256e-01 | 0.164 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 6.872295e-01 | 0.163 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 6.892372e-01 | 0.162 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 6.894622e-01 | 0.161 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 6.894622e-01 | 0.161 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 6.894622e-01 | 0.161 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 6.894622e-01 | 0.161 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 6.909894e-01 | 0.161 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 6.959690e-01 | 0.157 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 7.015661e-01 | 0.154 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 7.015661e-01 | 0.154 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 7.029614e-01 | 0.153 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 7.029614e-01 | 0.153 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 7.076703e-01 | 0.150 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 7.087797e-01 | 0.149 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 7.087797e-01 | 0.149 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 7.087797e-01 | 0.149 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 7.087797e-01 | 0.149 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 7.087797e-01 | 0.149 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.087797e-01 | 0.149 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 7.087797e-01 | 0.149 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 7.087797e-01 | 0.149 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 7.087797e-01 | 0.149 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 7.087797e-01 | 0.149 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 7.087797e-01 | 0.149 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 7.087797e-01 | 0.149 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 7.145943e-01 | 0.146 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 7.166092e-01 | 0.145 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 7.217679e-01 | 0.142 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 7.217679e-01 | 0.142 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 7.217679e-01 | 0.142 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 7.217679e-01 | 0.142 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 7.258891e-01 | 0.139 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 7.258891e-01 | 0.139 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 7.258891e-01 | 0.139 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 7.272487e-01 | 0.138 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 7.272487e-01 | 0.138 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 7.272487e-01 | 0.138 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 7.276882e-01 | 0.138 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 7.276882e-01 | 0.138 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 7.276882e-01 | 0.138 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 7.276882e-01 | 0.138 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 7.276882e-01 | 0.138 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 7.276882e-01 | 0.138 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 7.276882e-01 | 0.138 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 7.304013e-01 | 0.136 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 7.304013e-01 | 0.136 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 7.304013e-01 | 0.136 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 7.304013e-01 | 0.136 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 7.304013e-01 | 0.136 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 7.304013e-01 | 0.136 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 7.304013e-01 | 0.136 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 7.304013e-01 | 0.136 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 7.368292e-01 | 0.133 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 7.368292e-01 | 0.133 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 7.368292e-01 | 0.133 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 7.392310e-01 | 0.131 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 7.400606e-01 | 0.131 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 7.400606e-01 | 0.131 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 7.400606e-01 | 0.131 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 7.474716e-01 | 0.126 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 7.474716e-01 | 0.126 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 7.504188e-01 | 0.125 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 7.504188e-01 | 0.125 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 7.504188e-01 | 0.125 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 7.504188e-01 | 0.125 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 7.504188e-01 | 0.125 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 7.511891e-01 | 0.124 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 7.511891e-01 | 0.124 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 7.511891e-01 | 0.124 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 7.511891e-01 | 0.124 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 7.517543e-01 | 0.124 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 7.519822e-01 | 0.124 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 7.519822e-01 | 0.124 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 7.519822e-01 | 0.124 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 7.585009e-01 | 0.120 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 7.625635e-01 | 0.118 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 7.648687e-01 | 0.116 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 7.648687e-01 | 0.116 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 7.648687e-01 | 0.116 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 7.663182e-01 | 0.116 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 7.689341e-01 | 0.114 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 7.689511e-01 | 0.114 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 7.689511e-01 | 0.114 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 7.689511e-01 | 0.114 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 7.689511e-01 | 0.114 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 7.689511e-01 | 0.114 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 7.689511e-01 | 0.114 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 7.689511e-01 | 0.114 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 7.739943e-01 | 0.111 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 7.745032e-01 | 0.111 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 7.745032e-01 | 0.111 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 7.773710e-01 | 0.109 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 7.773710e-01 | 0.109 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 7.778899e-01 | 0.109 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 7.778899e-01 | 0.109 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 7.778899e-01 | 0.109 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 7.778899e-01 | 0.109 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 7.851196e-01 | 0.105 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 7.861083e-01 | 0.105 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 7.861083e-01 | 0.105 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 7.861083e-01 | 0.105 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 7.861083e-01 | 0.105 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 7.861083e-01 | 0.105 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 7.861083e-01 | 0.105 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 7.861083e-01 | 0.105 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 7.861083e-01 | 0.105 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 7.866932e-01 | 0.104 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 7.890058e-01 | 0.103 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 7.902750e-01 | 0.102 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 7.910085e-01 | 0.102 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 7.910085e-01 | 0.102 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 7.921454e-01 | 0.101 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 7.927444e-01 | 0.101 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 7.953186e-01 | 0.099 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 7.957012e-01 | 0.099 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 7.965508e-01 | 0.099 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 8.019925e-01 | 0.096 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 8.019925e-01 | 0.096 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 8.019925e-01 | 0.096 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 8.019925e-01 | 0.096 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 8.019925e-01 | 0.096 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 8.019925e-01 | 0.096 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 8.019925e-01 | 0.096 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 8.019925e-01 | 0.096 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 8.020466e-01 | 0.096 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 8.020466e-01 | 0.096 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 8.020466e-01 | 0.096 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 8.020466e-01 | 0.096 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 8.020466e-01 | 0.096 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 8.020466e-01 | 0.096 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 8.029989e-01 | 0.095 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 8.110145e-01 | 0.091 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 8.127958e-01 | 0.090 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 8.132276e-01 | 0.090 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 8.132276e-01 | 0.090 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 8.132276e-01 | 0.090 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 8.135774e-01 | 0.090 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 8.145043e-01 | 0.089 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 8.145104e-01 | 0.089 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 8.145104e-01 | 0.089 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 8.151237e-01 | 0.089 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 8.166979e-01 | 0.088 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 8.166979e-01 | 0.088 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 8.166979e-01 | 0.088 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 8.166979e-01 | 0.088 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 8.166979e-01 | 0.088 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.235116e-01 | 0.084 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 8.238406e-01 | 0.084 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 8.238406e-01 | 0.084 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 8.238406e-01 | 0.084 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 8.287010e-01 | 0.082 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 8.303120e-01 | 0.081 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.303120e-01 | 0.081 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 8.303120e-01 | 0.081 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 8.338356e-01 | 0.079 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 8.339083e-01 | 0.079 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 8.404081e-01 | 0.076 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 8.429157e-01 | 0.074 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 8.429157e-01 | 0.074 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.429157e-01 | 0.074 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 8.429157e-01 | 0.074 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 8.429157e-01 | 0.074 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 8.429157e-01 | 0.074 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 8.434532e-01 | 0.074 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 8.460177e-01 | 0.073 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 8.474616e-01 | 0.072 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 8.489242e-01 | 0.071 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 8.504389e-01 | 0.070 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 8.524974e-01 | 0.069 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 8.524974e-01 | 0.069 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 8.545840e-01 | 0.068 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 8.545840e-01 | 0.068 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 8.545840e-01 | 0.068 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 8.545840e-01 | 0.068 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 8.545840e-01 | 0.068 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 8.545840e-01 | 0.068 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 8.545840e-01 | 0.068 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 8.551321e-01 | 0.068 | 1 | 1 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 8.558868e-01 | 0.068 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 8.571461e-01 | 0.067 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 8.609277e-01 | 0.065 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 8.610625e-01 | 0.065 | 0 | 0 |
| Depurination | R-HSA-73927 | 8.610625e-01 | 0.065 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 8.610625e-01 | 0.065 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 8.610625e-01 | 0.065 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 8.621046e-01 | 0.064 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 8.631221e-01 | 0.064 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 8.653862e-01 | 0.063 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 8.653862e-01 | 0.063 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 8.653862e-01 | 0.063 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 8.653862e-01 | 0.063 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 8.653862e-01 | 0.063 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 8.653862e-01 | 0.063 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 8.653862e-01 | 0.063 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 8.653862e-01 | 0.063 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 8.726328e-01 | 0.059 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 8.753866e-01 | 0.058 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 8.753866e-01 | 0.058 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 8.753866e-01 | 0.058 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 8.753866e-01 | 0.058 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 8.753866e-01 | 0.058 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 8.753866e-01 | 0.058 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 8.753866e-01 | 0.058 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 8.753866e-01 | 0.058 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 8.757478e-01 | 0.058 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 8.768401e-01 | 0.057 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 8.768401e-01 | 0.057 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 8.768401e-01 | 0.057 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 8.768401e-01 | 0.057 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 8.829435e-01 | 0.054 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 8.840934e-01 | 0.054 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 8.846445e-01 | 0.053 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 8.846445e-01 | 0.053 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 8.846445e-01 | 0.053 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 8.846445e-01 | 0.053 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 8.846445e-01 | 0.053 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 8.846445e-01 | 0.053 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 8.846445e-01 | 0.053 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 8.889587e-01 | 0.051 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 8.909494e-01 | 0.050 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 8.909494e-01 | 0.050 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 8.909494e-01 | 0.050 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 8.922162e-01 | 0.050 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 8.927056e-01 | 0.049 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 8.932152e-01 | 0.049 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 8.932152e-01 | 0.049 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 8.932152e-01 | 0.049 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 8.946957e-01 | 0.048 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 8.946957e-01 | 0.048 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 8.946957e-01 | 0.048 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 8.946957e-01 | 0.048 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 8.946957e-01 | 0.048 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 9.001650e-01 | 0.046 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 9.001650e-01 | 0.046 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 9.011496e-01 | 0.045 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 9.011496e-01 | 0.045 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.011496e-01 | 0.045 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 9.021028e-01 | 0.045 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.026655e-01 | 0.044 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 9.074794e-01 | 0.042 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.084949e-01 | 0.042 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.084949e-01 | 0.042 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.084949e-01 | 0.042 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.084949e-01 | 0.042 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.084949e-01 | 0.042 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.093201e-01 | 0.041 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.093201e-01 | 0.041 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 9.103412e-01 | 0.041 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 9.125221e-01 | 0.040 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 9.147703e-01 | 0.039 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 9.147703e-01 | 0.039 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 9.147703e-01 | 0.039 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 9.147703e-01 | 0.039 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 9.150680e-01 | 0.039 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 9.152948e-01 | 0.038 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 9.152948e-01 | 0.038 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 9.152948e-01 | 0.038 | 0 | 0 |
| Attachment of bacteria to epithelial cells | R-HSA-9638630 | 9.152948e-01 | 0.038 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 9.152948e-01 | 0.038 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.152948e-01 | 0.038 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 9.152948e-01 | 0.038 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.215897e-01 | 0.035 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.215897e-01 | 0.035 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 9.215897e-01 | 0.035 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 9.215897e-01 | 0.035 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.215897e-01 | 0.035 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.238467e-01 | 0.034 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.272341e-01 | 0.033 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 9.274172e-01 | 0.033 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.274172e-01 | 0.033 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.274172e-01 | 0.033 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.274172e-01 | 0.033 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.274172e-01 | 0.033 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 9.274172e-01 | 0.033 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.277192e-01 | 0.033 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 9.279172e-01 | 0.032 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.317869e-01 | 0.031 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 9.328119e-01 | 0.030 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.328119e-01 | 0.030 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 9.328119e-01 | 0.030 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.328119e-01 | 0.030 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 9.378059e-01 | 0.028 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 9.378059e-01 | 0.028 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.378059e-01 | 0.028 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.378059e-01 | 0.028 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 9.389583e-01 | 0.027 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.397597e-01 | 0.027 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 9.415167e-01 | 0.026 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 9.424291e-01 | 0.026 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.424291e-01 | 0.026 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 9.424291e-01 | 0.026 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 9.451146e-01 | 0.025 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 9.451146e-01 | 0.025 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 9.451146e-01 | 0.025 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.454265e-01 | 0.024 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.467088e-01 | 0.024 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.485011e-01 | 0.023 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 9.493474e-01 | 0.023 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 9.506706e-01 | 0.022 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.516382e-01 | 0.022 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.539367e-01 | 0.020 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.539367e-01 | 0.020 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.540989e-01 | 0.020 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.543381e-01 | 0.020 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 9.543381e-01 | 0.020 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 9.543381e-01 | 0.020 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.554582e-01 | 0.020 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.577331e-01 | 0.019 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.577331e-01 | 0.019 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.577331e-01 | 0.019 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.577331e-01 | 0.019 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 9.577331e-01 | 0.019 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.577331e-01 | 0.019 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.587908e-01 | 0.018 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.589126e-01 | 0.018 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.590062e-01 | 0.018 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 9.606265e-01 | 0.017 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.608759e-01 | 0.017 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.608759e-01 | 0.017 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.608759e-01 | 0.017 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.612044e-01 | 0.017 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.616682e-01 | 0.017 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.633756e-01 | 0.016 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 9.637852e-01 | 0.016 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 9.637852e-01 | 0.016 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 9.637852e-01 | 0.016 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 9.637852e-01 | 0.016 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 9.637852e-01 | 0.016 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.637852e-01 | 0.016 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.637852e-01 | 0.016 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 9.645737e-01 | 0.016 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.649889e-01 | 0.015 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 9.652684e-01 | 0.015 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.664783e-01 | 0.015 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 9.664783e-01 | 0.015 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 9.664783e-01 | 0.015 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 9.664783e-01 | 0.015 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 9.664783e-01 | 0.015 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.664783e-01 | 0.015 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.671890e-01 | 0.014 | 0 | 0 |
| Biofilm formation | R-HSA-9931953 | 9.689713e-01 | 0.014 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.709670e-01 | 0.013 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.710386e-01 | 0.013 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.711578e-01 | 0.013 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.711968e-01 | 0.013 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.712790e-01 | 0.013 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.712790e-01 | 0.013 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.712790e-01 | 0.013 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.712790e-01 | 0.013 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 9.712790e-01 | 0.013 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 9.712790e-01 | 0.013 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.712790e-01 | 0.013 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.734152e-01 | 0.012 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.734152e-01 | 0.012 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.753927e-01 | 0.011 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.753927e-01 | 0.011 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.753927e-01 | 0.011 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.753927e-01 | 0.011 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.756555e-01 | 0.011 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 9.769600e-01 | 0.010 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 9.772231e-01 | 0.010 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 9.772231e-01 | 0.010 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.772231e-01 | 0.010 | 0 | 0 |
| Translation | R-HSA-72766 | 9.779753e-01 | 0.010 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.781842e-01 | 0.010 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 9.783644e-01 | 0.009 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.789175e-01 | 0.009 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.792566e-01 | 0.009 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.804860e-01 | 0.009 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.804860e-01 | 0.009 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 9.805827e-01 | 0.009 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.807969e-01 | 0.008 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.819100e-01 | 0.008 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.819378e-01 | 0.008 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.819378e-01 | 0.008 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.819378e-01 | 0.008 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.819378e-01 | 0.008 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 9.824940e-01 | 0.008 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 9.829927e-01 | 0.007 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.832818e-01 | 0.007 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.832818e-01 | 0.007 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.832818e-01 | 0.007 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.845258e-01 | 0.007 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 9.845258e-01 | 0.007 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.845258e-01 | 0.007 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.856773e-01 | 0.006 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 9.860717e-01 | 0.006 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.866107e-01 | 0.006 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 9.867431e-01 | 0.006 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.867431e-01 | 0.006 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.877297e-01 | 0.005 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.878153e-01 | 0.005 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.894058e-01 | 0.005 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.894883e-01 | 0.005 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.894883e-01 | 0.005 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.894883e-01 | 0.005 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.900385e-01 | 0.004 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.901260e-01 | 0.004 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 9.902321e-01 | 0.004 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 9.907434e-01 | 0.004 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 9.908144e-01 | 0.004 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 9.909950e-01 | 0.004 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.909950e-01 | 0.004 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.925001e-01 | 0.003 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.927883e-01 | 0.003 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 9.928602e-01 | 0.003 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 9.931789e-01 | 0.003 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.943394e-01 | 0.002 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.943394e-01 | 0.002 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.947609e-01 | 0.002 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.947609e-01 | 0.002 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.950053e-01 | 0.002 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 9.950208e-01 | 0.002 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.951511e-01 | 0.002 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.958465e-01 | 0.002 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.958823e-01 | 0.002 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.967867e-01 | 0.001 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.968719e-01 | 0.001 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.968719e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.969526e-01 | 0.001 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.971699e-01 | 0.001 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.972480e-01 | 0.001 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.973938e-01 | 0.001 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.975843e-01 | 0.001 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.975843e-01 | 0.001 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 9.976076e-01 | 0.001 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.980019e-01 | 0.001 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.980722e-01 | 0.001 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.980852e-01 | 0.001 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.981808e-01 | 0.001 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.982015e-01 | 0.001 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.983600e-01 | 0.001 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.983672e-01 | 0.001 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.983672e-01 | 0.001 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.987001e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.987001e-01 | 0.001 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 9.988867e-01 | 0.000 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 9.991128e-01 | 0.000 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.991177e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.991658e-01 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.991850e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.993529e-01 | 0.000 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.994012e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.994272e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.994903e-01 | 0.000 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.994966e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.995334e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.995575e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.997293e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.997329e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.997448e-01 | 0.000 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.997448e-01 | 0.000 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.997815e-01 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.997823e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.998420e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.998580e-01 | 0.000 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.998913e-01 | 0.000 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.999153e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999263e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.999517e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.999538e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999646e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999686e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999688e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999787e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999809e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.999823e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999936e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.999945e-01 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.999945e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999946e-01 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.999957e-01 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 9.999967e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999972e-01 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.999974e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999979e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999981e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999993e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999998e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999999e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999999e-01 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
