CK2A2

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0MZ66 S473 Sugiyama SHTN1 KIAA1598 LGtLNKSTSSRsLKsLDPENsEtELERILRRRKVtAEADss
A0MZ66 T475 Sugiyama SHTN1 KIAA1598 tLNKSTSSRsLKsLDPENsEtELERILRRRKVtAEADsssP
O00170 S43 Sugiyama AIP XAP2 GELPDFQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELI
O00203 S276 Sugiyama AP3B1 ADTB3A FVSPWKEGDELEDNGKNFyEsDDDQKEKTDKKKKPYTMDPD
O00264 S181 Sugiyama PGRMC1 HPR6.6 PGRMC TFKYHHVGKLLKEGEEPtVysDEEEPKDEsARKND______
O00264 S57 Sugiyama PGRMC1 HPR6.6 PGRMC LCIFLLYKIVRGDQPAAsGDsDDDEPPPLPRLKRRDFtPAE
O00505 S60 Sugiyama KPNA3 QIP2 KRDEHLLKKRNVPQEEsLEDsDVDADFKAQNVTLEAILQNA
O00566 S167 Sugiyama MPHOSPH10 MPP10 EMGERAENSSKsDLRKsPVFsDEDsDLDFDISKLEQQSKVQ
O00566 S171 Sugiyama MPHOSPH10 MPP10 RAENSSKsDLRKsPVFsDEDsDLDFDISKLEQQSKVQNKGQ
O00567 S520 Sugiyama NOP56 NOL5A sIsFsKPKKKKsFsKEELMssDLEEtAGstsIPKRKKstPK
O00629 S60 Sugiyama KPNA4 QIP1 KRDEHLLKRRNVPHEDICEDsDIDGDYRVQNtsLEAIVQNA
O14950 T135 Sugiyama MYL12B MRLC2 MYLC2B TGTIQEDYLRELLttMGDRFtDEEVDELyREAPIDKKGNFN
O14958 S385 SIGNOR|iPTMNet CASQ2 VLSGKINTEDDDEDDDDDDNsDEEDNDDsDDDDDE______
O15173 T211 Sugiyama PGRMC2 DG6 PMBP KEKYDYVGRLLKPGEEPsEytDEEDtKDHNKQD________
O15350 T27 PSP TP73 P73 TSPDGGTTFEHLWSSLEPDStyFDLPQSSRGNNEVVGGTDs
O15460 S346 Sugiyama P4HA2 UNQ290/PRO330 PFKEEDEWDSPHIVRYyDVMsDEEIERIKEIAKPKLARATV
O43150 S701 Sugiyama ASAP2 DDEF2 KIAA0400 FNSHVHVEYEWRLLHEDLDEsDDDMDEKLQPSPNRREDRPI
O43583 T86 Sugiyama DENR DRP1 H14 AKLtVENsPKQEAGIsEGQGtAGEEEEKKKQKRGGRGQIKQ
O43719 S529 Sugiyama HTATSF1 KNDCEENGLAKEsEDDLNKEsEEEVGPTKESEEDDSEKESD
O43719 S561 Sugiyama HTATSF1 EDDSEKESDEDCSEKQsEDGsEREFEENGLEKDLDEEGsEK
O43719 S597 Sugiyama HTATSF1 EGsEKELHENVLDKELEENDsENsEFEDDGsEKVLDEEGsE
O43719 S600 Sugiyama HTATSF1 EKELHENVLDKELEENDsENsEFEDDGsEKVLDEEGsEREF
O43719 S642 Sugiyama HTATSF1 EDsDEKEEEEDtyEKVFDDEsDEKEDEEyADEKGLEAADKK
O43719 S676 Sugiyama HTATSF1 LEAADKKAEEGDADEKLFEEsDDKEDEDADGKEVEDADEKL
O43852 S261 Sugiyama CALU RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK
O43852 S277 Sugiyama CALU WILPsDyDHAEAEARHLVyEsDQNKDGKLTKEEIVDKyDLF
O43852 Y275 Sugiyama CALU KDWILPsDyDHAEAEARHLVyEsDQNKDGKLTKEEIVDKyD
O43896 S1092 SIGNOR|ELM|iPTMNet KIF1C KIAA0706 RPPGPRYPPYttPPRMRRQRsAPDLKESGAAV_________
O60220 S96 Sugiyama TIMM8A DDP DDP1 TIM8A FILNRLEQTQKSKPVFSEsLsD___________________
O60231 S103 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 AEREARALLEKNRSYRLLEDsEEssEEtVsRAGsSLQKKRK
O60231 S106 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 EARALLEKNRSYRLLEDsEEssEEtVsRAGsSLQKKRKKRK
O60341 S131 Sugiyama KDM1A AOF2 KDM1 KIAA0601 LSD1 sRRKRAKVEyREMDEsLANLsEDEyysEEERNAKAEKEKKL
O60343 S485 Sugiyama TBC1D4 AS160 KIAA0603 CERIEGLYPPRAKLVIQRHLssLtDNEQADIFERVQKMKPV
O60343 T488 Sugiyama TBC1D4 AS160 KIAA0603 IEGLYPPRAKLVIQRHLssLtDNEQADIFERVQKMKPVSDQ
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60832 S485 Sugiyama DKC1 NOLA4 LIKKEKKKSKKDKKAKAGLEsGAEPGDGDsDttKKKKKKKK
O60841 S113 Sugiyama EIF5B IF2 KIAA0741 sKDKKKKGQKGKKQsFDDNDsEELEDKDsKSKKTAKPKVEM
O60841 S135 Sugiyama EIF5B IF2 KIAA0741 ELEDKDsKSKKTAKPKVEMysGsDDDDDFNKLPKKAKGKAQ
O60841 S137 Sugiyama EIF5B IF2 KIAA0741 EDKDsKSKKTAKPKVEMysGsDDDDDFNKLPKKAKGKAQKS
O60841 S164 Sugiyama EIF5B IF2 KIAA0741 NKLPKKAKGKAQKSNKKWDGsEEDEDNsKKIKERsRINssG
O60841 S182 Sugiyama EIF5B IF2 KIAA0741 DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK
O60841 S186 Sugiyama EIF5B IF2 KIAA0741 EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN
O60841 S190 Sugiyama EIF5B IF2 KIAA0741 NsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGP
O60841 S214 Sugiyama EIF5B IF2 KIAA0741 LQsRKGQKKNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAE
O60885 S601 Sugiyama BRD4 HUNK1 SNVSKKEPAPMKsKPPPtYEsEEEDKCKPMSYEEKRQLSLD
O60927 S77 Sugiyama PPP1R11 HCGV TCTE5 ssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRGHRKG
O60936 T149 SIGNOR NOL3 ARC NOP RASDPDEAGGPEGsEAVQsGtPEEPEPELEAEAsKEAEPEP
O75116 S937 Sugiyama ROCK2 KIAA0619 ITLTKADSEQLARsIAEEQysDLEKEKIMKELEIKEMMARH
O75379 S30 ELM VAMP4 NDDDVTGsVKsERRNLLEDDsDEEEDFFLRGPSGPRFGPRN
O75391 S114 Sugiyama SPAG7 sFGEDDDCRYVMIFKKEFAPsDEELDSYRRGEEWDPQKAEE
O75400 S938 Sugiyama PRPF40A FBP11 FLAF1 FNBP3 HIP10 HYPA HSPC225 SPKKKtGKDsGNWDtsGsELsEGELEKRRRtLLEQLDDDQ_
O75822 S127 Sugiyama EIF3J EIF3S1 PRO0391 VLtPEEQLADKLRLKKLQEEsDLELAKEtFGVNNAVyGIDA
O76094 S610 Sugiyama SRP72 KKGKKKDQIGKGtQGAtAGAssELDAsKtVssPPtsPRPGs
O95218 S120 Sugiyama ZRANB2 ZIS ZNF265 tGYGGGFNERENVEyIEREEsDGEyDEFGRKKKKYRGKAVG
O95218 S188 Sugiyama ZRANB2 ZIS ZNF265 KLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRRSRSKSRS
O95340 S180 Sugiyama PAPSS2 ATPSK2 VKGLYKRARAGEIKGFTGIDsDyEKPEtPERVLKTNLSTVS
O95456 T18 Sugiyama PSMG1 C21LRP DSCR2 PAC1 ___MAAtFFGEVVKAPCRAGtEDEEEEEEGRREtPEDREVR
O95671 S239 Sugiyama ASMTL DLRRsVKHDsIPAADtFEDLsDVEGGGsEPTQRDAGsRDEK
O95747 S339 Sugiyama OXSR1 KIAA1101 OSR1 RRVPGssGRLHKtEDGGWEWsDDEFDEEsEEGKAAIsQLRs
O95786 T770 SIGNOR RIGI DDX58 KEQINMYKEKMMNDsILRLQtWDEAVFREKILHIQTHEKFI
O95816 S73 Sugiyama BAG2 KEILLEMIHSIQNSQDMRQIsDGEREELNLTANRLMGRTLT
O95831 S116 Sugiyama AIFM1 AIF PDCD8 NERIsGLGLtPEQKQKKAALsAsEGEEVPQDKAPSHVPFLL
O95831 S118 Sugiyama AIFM1 AIF PDCD8 RIsGLGLtPEQKQKKAALsAsEGEEVPQDKAPSHVPFLLIG
P00338 S310 Sugiyama LDHA PIG19 SVPCILGQNGISDLVKVTLtsEEEARLKKsADtLWGIQKEL
P00338 T220 Sugiyama LDHA PIG19 VWSGMNVAGVSLKtLHPDLGtDKDKEQWKEVHKQVVEsAyE
P00338 T309 Sugiyama LDHA PIG19 LSVPCILGQNGISDLVKVTLtsEEEARLKKsADtLWGIQKE
P00736 S206 ELM C1R THSCQAECSSELYTEASGYIsSLEYPRSYPPDLRCNYSIRV
P01106 T73 iPTMNet MYC BHLHE39 SELQPPAPSEDIWKKFELLPtPPLsPsRRsGLCsPSyVAVT
P01375 S2 ELM TNF TNFA TNFSF2 ___________________MsTESMIRDVELAEEALPKKTG
P04004 T69 ELM VTN SCCTDYTAECKPQVTRGDVFtMPEDEYtVYDDGEEKNNATV
P04004 T76 ELM VTN AECKPQVTRGDVFtMPEDEYtVYDDGEEKNNATVHEQVGGP
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04198 S261 SIGNOR|ELM|iPTMNet MYCN BHLHE37 NMYC GRQTSGGDHKALSTSGEDTLsDsDDEDDEEEDEEEEIDVVT
P04198 S263 SIGNOR|ELM|iPTMNet MYCN BHLHE37 NMYC QTSGGDHKALSTSGEDTLsDsDDEDDEEEDEEEEIDVVTVE
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04818 S124 GPS6|PSP TYMS TS OK/SW-cl.29 KGVKIWDANGsRDFLDsLGFsTREEGDLGPVyGFQWRHFGA
P05187 S192 Sugiyama ALPP PLAP RVQHAsPAGtyAHtVNRNWysDADVPASARQEGCQDIATQL
P05198 T279 Sugiyama EIF2S1 EIF2A KEKIEEKRGVFNVQMEPKVVtDtDEtELARQMERLERENAE
P05198 T281 Sugiyama EIF2S1 EIF2A KIEEKRGVFNVQMEPKVVtDtDEtELARQMERLERENAEVD
P05386 S101 Sugiyama RPLP1 RRP1 APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S102 Sugiyama RPLP2 D11S2243E RPP2 PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05388 S304 Sugiyama RPLP0 AttAAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD_______
P05388 S307 Sugiyama RPLP0 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
P05412 S243 ELM JUN QALKEEPQtVPEMPGEtPPLsPIDMEsQERIKAERKRMRNR
P05412 S249 ELM JUN PQtVPEMPGEtPPLsPIDMEsQERIKAERKRMRNRIAASKC
P05412 T231 ELM JUN LPQQMPVQHPRLQALKEEPQtVPEMPGEtPPLsPIDMEsQE
P05455 S366 ELM|Sugiyama SSB AQPGsGKGKVQFQGKKtKFAsDDEHDEHDENGAtGPVKRAR
P06127 S482 ELM CD5 LEU1 LSAyPALEGALHRSSMQPDNssDsDyDLHGAQRL_______
P06127 S483 ELM CD5 LEU1 SAyPALEGALHRSSMQPDNssDsDyDLHGAQRL________
P06127 S485 ELM CD5 LEU1 yPALEGALHRSSMQPDNssDsDyDLHGAQRL__________
P06401 S81 ELM PGR NR3C3 PRPCQGQDPSDEKTQDQQSLsDVEGAYSRAEATRGAGGSSS
P06454 T13 ELM PTMA TMSA ________MsDAAVDtssEIttKDLKEKKEVVEEAENGRDA
P06454 T14 ELM PTMA TMSA _______MsDAAVDtssEIttKDLKEKKEVVEEAENGRDAP
P06454 T8 ELM PTMA TMSA _____________MsDAAVDtssEIttKDLKEKKEVVEEAE
P06493 S39 ELM CDK1 CDC2 CDC28A CDKN1 P34CDC2 yKGRHKTTGQVVAMKKIRLEsEEEGVPstAIREIsLLKELR
P06744 S185 ELM GPI LMVTEALKPYSsGGPRVWYVsNIDGTHIAKTLAQLNPESSL
P06748 S125 Sugiyama NPM1 NPM GsGPVHIsGQHLVAVEEDAEsEDEEEEDVKLLsIsGKRsAP
P07237 S88 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNG
P07237 T85 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB KAAGKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFF
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S231 ELM|Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA SQFIGyPITLFVEKERDKEVsDDEAEEKEDKEEEKEKEEKE
P07900 S263 ELM|Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EEKEKEEKEsEDKPEIEDVGsDEEEEKKDGDKKKKKKIKEK
P07900 S391 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P07900 S470 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA HEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKH
P07900 T467 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKEN
P07910 S260 SIGNOR|ELM|iPTMNet HNRNPC HNRPC ssVKKDETNVKMEsEGGADDsAEEGDLLDDDDNEDRGDDQL
P08047 T579 ELM SP1 TSFP1 GDHGAQLGLHGAGGDGIHDDtAGGEEGENSPDAQPQAGRRT
P08195 S406 Sugiyama SLC3A2 MDU1 QQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNAT
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S226 ELM|Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sQFIGyPItLyLEKEREKEIsDDEAEEEKGEKEEEDKDDEE
P08238 S255 ELM|Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GEKEEEDKDDEEKPKIEDVGsDEEDDsGKDKKKKTKKIKEK
P08238 S383 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P08238 S460 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 T459 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEt
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08575 S1001 SIGNOR PTPRC CD45 DYNRVPLKHELEMSKESEHDsDEssDDDsDSEEPSKYINAS
P08575 S1004 SIGNOR PTPRC CD45 RVPLKHELEMSKESEHDsDEssDDDsDSEEPSKYINASFIM
P08575 S1005 SIGNOR PTPRC CD45 VPLKHELEMSKESEHDsDEssDDDsDSEEPSKYINASFIMS
P08575 S1009 SIGNOR PTPRC CD45 HELEMSKESEHDsDEssDDDsDSEEPSKYINASFIMSYWKP
P09497 S11 SIGNOR|iPTMNet CLTB __________MADDFGFFSSsEsGAPEAAEEDPAAAFLAQQ
P09497 S13 SIGNOR|iPTMNet CLTB ________MADDFGFFSSsEsGAPEAAEEDPAAAFLAQQES
P09629 S133 ELM HOXB7 HOX2C QRDSDLAAESNFRIYPWMRssGTDRKRGRQTYTRYQTLELE
P09629 T204 ELM HOXB7 HOX2C WFQNRRMKWKKENKTAGPGttGQDRAEAEEEEEE_______
P09960 S236 Sugiyama LTA4H LTA4 GPRTLVWSEKEQVEKSAyEFsETEsMLKIAEDLGGPYVWGQ
P0CAP2 S364 Sugiyama POLR2M GRINL1A NPEGESSGRYREVRDEDDDWssDEF________________
P0DP23 S102 ELM CALM1 CALM CAM CAM1 sEEEIREAFRVFDKDGNGyIsAAELRHVMTNLGEKLtDEEV
P0DP23 T80 ELM CALM1 CALM CAM CAM1 GNGTIDFPEFLTMMARKMKDtDsEEEIREAFRVFDKDGNGy
P10242 S11 ELM MYB __________MARRPRHSIYssDEDDEDFEMCDHDYDGLLP
P10242 S12 ELM MYB _________MARRPRHSIYssDEDDEDFEMCDHDYDGLLPK
P10696 S189 Sugiyama ALPG ALPPL ALPPL2 RVQHASPAGAYAHTVNRNWysDADVPASARQEGCQDIATQL
P10809 S398 Sugiyama HSPD1 HSP60 LDVttsEyEKEKLNERLAKLsDGVAVLKVGGtsDVEVNEKK
P10809 S410 Sugiyama HSPD1 HSP60 LNERLAKLsDGVAVLKVGGtsDVEVNEKKDRVtDALNAtRA
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11388 S1106 Sugiyama TOP2A TOP2 PVKAWKEAQQKVPDEEENEEsDNEKEtEKsDsVTDSGPTFN
P11388 S1377 ELM|Sugiyama TOP2A TOP2 KtKTsPKLsNKELKPQKsVVsDLEADDVKGsVPLsssPPAt
P11388 S1525 ELM TOP2A TOP2 AVAPRAKSVRAKKPIKYLEEsDEDDLF______________
P11388 T1343 ELM TOP2A TOP2 KTKFTMDLDsDEDFsDFDEKtDDEDFVPsDAsPPKtKTsPK
P11473 S208 ELM VDR NR1I1 DHCITSSDMMDSSSFSNLDLsEEDSDDPSVTLELSQLSMLP
P11586 S318 Sugiyama MTHFD1 MTHFC MTHFD FKPGKWMIQYNNLNLKTPVPsDIDIsRSCKPKPIGKLAREI
P11586 T511 Sugiyama MTHFD1 MTHFC MTHFD DIQIRRLKRLGIEKTDPTTLtDEEINRFARLDIDPEtITWQ
P11836 S231 SIGNOR|ELM|iPTMNet MS4A1 CD20 IVENEWKRTCSRPKsNIVLLsAEEKKEQTIEIKEEVVGLtE
P11836 S289 SIGNOR|ELM|iPTMNet MS4A1 CD20 EEEEEETETNFPEPPQDQESsPIENDSSP____________
P11836 T250 SIGNOR|ELM|iPTMNet MS4A1 CD20 LsAEEKKEQTIEIKEEVVGLtEtssQPKNEEDIEIIPIQEE
P12259 S692 ELM F5 SKKLRLKFRDVKCIPDDDEDsyEIFEPPESTVMATRKMHDR
P12830 S851 ELM CDH1 CDHE UVO LVFDYEGsGsEAAsLSsLNssEsDKDQDYDYLNEWGNRFKK
P13349 S133 SIGNOR|ELM|iPTMNet MYF5 BHLHC2 NPNQRLPKVEILRNAIRYIEsLQELLREQVENYYSLPGQSC
P13349 S49 SIGNOR|ELM|iPTMNet MYF5 BHLHC2 GDEFVPRVAAFGAHKAELQGsDEDEHVRAPTGHHQAGHCLM
P13667 S468 Sugiyama PDIA4 ERP70 ERP72 ytFAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAM
P13667 S470 Sugiyama PDIA4 ERP70 ERP72 FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP
P13798 S185 Sugiyama APEH D3F15S2 D3S48E DNF15S2 VAEKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQ
P13798 S187 Sugiyama APEH D3F15S2 D3S48E DNF15S2 EKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQFV
P13798 S8 Sugiyama APEH D3F15S2 D3S48E DNF15S2 _____________MERQVLLsEPEEAAALyRGLSRQPALsA
P13861 S78 Sugiyama PRKAR2A PKR2 PRKAR2 sLGHPPPEPGPDRVADAKGDsEsEEDEDLEVPVPsRFNRRV
P13861 S80 Sugiyama PRKAR2A PKR2 PRKAR2 GHPPPEPGPDRVADAKGDsEsEEDEDLEVPVPsRFNRRVsV
P14598 S208 ELM NCF1 NOXO2 SH3PXD1A KSESGWWFCQMKAKRGWIPAsFLEPLDSPDETEDPEPNyAG
P14598 S283 ELM NCF1 NOXO2 SH3PXD1A WWVIRKDDVTGYFPSMyLQKsGQDVsQAQRQIKRGAPPRRs
P14598 S348 ELM NCF1 NOXO2 SH3PXD1A sVRFLQQRRRQARPGPQsPGsPLEEERQtQRsKPQPAVPPR
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S306 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 TETVEEPMEEEEAAKEEKEEsDDEAAVEEEEEEKKPKTKKV
P14625 S439 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 TDDFHDMMPKyLNFVKGVVDsDDLPLNVsREtLQQHKLLKV
P15531 S120 Sugiyama NME1 NDPKA NM23 KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P17096 S102 SIGNOR|ELM|iPTMNet HMGA1 HMGIY KPRGRPKKLEKEEEEGIsQEssEEEQ_______________
P17096 S103 SIGNOR|ELM|iPTMNet HMGA1 HMGIY PRGRPKKLEKEEEEGIsQEssEEEQ________________
P17096 S99 SIGNOR|ELM|iPTMNet HMGA1 HMGIY PGRKPRGRPKKLEKEEEEGIsQEssEEEQ____________
P17931 S12 iPTMNet LGALS3 MAC2 _________MADNFsLHDALsGSGNPNPQGWPGAWGNQPAG
P17931 S6 iPTMNet LGALS3 MAC2 _______________MADNFsLHDALsGSGNPNPQGWPGAW
P17936 S138 ELM IGFBP3 IBP3 SAVSRLRAYLLPAPPAPGNAsEsEEDRsAGsVEsPSVSsTH
P17936 S140 ELM IGFBP3 IBP3 VSRLRAYLLPAPPAPGNAsEsEEDRsAGsVEsPSVSsTHRV
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18031 S352 iPTMNet PTPN1 PTP1B QWVKEEtQEDKDCPIKEEKGsPLNAAPYGIEsMsQDtEVRS
P18031 S378 iPTMNet PTPN1 PTP1B PYGIEsMsQDtEVRSRVVGGsLRGAQAAsPAKGEPsLPEKD
P18031 S386 iPTMNet PTPN1 PTP1B QDtEVRSRVVGGsLRGAQAAsPAKGEPsLPEKDEDHALSYW
P18146 S378 ELM EGR1 KROX24 ZNF225 HIRIHTGQKPFQCRICMRNFsRSDHLTTHIRTHtGEKPFAC
P18846 S36 ELM ATF1 PGSAVQGAHISHIAQQVSSLsEsEEsQDsSDsIGssQKAHG
P18858 S66 ELM LIG1 VsEsDsPVKRPGRKAARVLGsEGEEEDEALsPAKGQKPALD
P18887 S485 PSP XRCC1 QEDIDIEGVQsEGQDNGAEDsGDtEDELRRVAEQKEHRLPP
P18887 S518 SIGNOR|iPTMNet|PSP XRCC1 QKEHRLPPGQEENGEDPyAGstDENtDsEEHQEPPDLPVPE
P18887 T488 PSP XRCC1 IDIEGVQsEGQDNGAEDsGDtEDELRRVAEQKEHRLPPGQE
P18887 T519 SIGNOR|iPTMNet|PSP XRCC1 KEHRLPPGQEENGEDPyAGstDENtDsEEHQEPPDLPVPEL
P18887 T523 SIGNOR|iPTMNet|PSP XRCC1 LPPGQEENGEDPyAGstDENtDsEEHQEPPDLPVPELPDFF
P19105 T134 Sugiyama MYL12A MLCB MRLC3 RLC TGTIQEDYLRELLttMGDRFtDEEVDELyREAPIDKKGNFN
P19338 S619 Sugiyama NCL RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK
P19784 S333 Sugiyama CSNK2A2 CK2A2 RLTAKEAMEHPyFyPVVKEQsQPCADNAVLssGLtAAR___
P19784 S343 Sugiyama CSNK2A2 CK2A2 PyFyPVVKEQsQPCADNAVLssGLtAAR_____________
P19784 S344 Sugiyama CSNK2A2 CK2A2 yFyPVVKEQsQPCADNAVLssGLtAAR______________
P19784 T347 Sugiyama CSNK2A2 CK2A2 PVVKEQsQPCADNAVLssGLtAAR_________________
P20042 S67 Sugiyama EIF2S2 EIF2B EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK
P21127 S277 Sugiyama CDK11B CDC2L1 CDK11 PITSLREA PK58 APAQKPAQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSA
P21127 S283 Sugiyama CDK11B CDC2L1 CDK11 PITSLREA PK58 AQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSAESGSGS
P21291 S192 Sugiyama CSRP1 CSRP CYRP AKNFGPKGFGFGQGAGALVHsE___________________
P21673 S146 SIGNOR|ELM|iPTMNet SAT1 SAT HFLVAEWNEPSINFYKRRGAsDLsSEEGWRLFKIDKEYLLK
P21673 S149 SIGNOR|ELM|iPTMNet SAT1 SAT VAEWNEPSINFYKRRGAsDLsSEEGWRLFKIDKEYLLKMAT
P21673 T10 ELM|iPTMNet SAT1 SAT ___________MAKFVIRPAtAADCSDILRLIKELAKYEYM
P22059 S190 Sugiyama OSBP OSBP1 QRWVTALELAKAKAVKMLAEsDEsGDEEsVsQtDKTELQNT
P22059 S193 Sugiyama OSBP OSBP1 VTALELAKAKAVKMLAEsDEsGDEEsVsQtDKTELQNTLRT
P22314 S13 ELM UBA1 A1S9T UBE1 ________MSSsPLSKKRRVsGPDPKPGsNCsPAQsVLsEV
P22314 S46 Sugiyama UBA1 A1S9T UBE1 AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P24534 S106 SIGNOR|iPTMNet EEF1B2 EEF1B EF1B DttGsGAtDsKDDDDIDLFGsDDEEEsEEAKRLREERLAQY
P24534 S112 SIGNOR|iPTMNet EEF1B2 EEF1B EF1B AtDsKDDDDIDLFGsDDEEEsEEAKRLREERLAQYESKKAK
P25205 S711 Sugiyama MCM3 RRKTRQPDAKDGDsyDPyDFsDtEEEMPQVHtPKTADsQEt
P25205 T713 Sugiyama MCM3 KTRQPDAKDGDsyDPyDFsDtEEEMPQVHtPKTADsQEtKE
P25788 S243 ELM PSMA3 HC8 PSC8 GRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM________
P25788 S250 ELM|Sugiyama PSMA3 HC8 PSC8 KDIREEAEKyAKEsLKEEDEsDDDNM_______________
P25963 S283 ELM NFKBIA IKBA MAD3 NFKBI TRIQQQLGQLTLENLQMLPEsEDEEsyDtEsEFTEFtEDEL
P25963 S32 ELM NFKBIA IKBA MAD3 NFKBI AMEGPRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEI
P25963 S36 ELM NFKBIA IKBA MAD3 NFKBI PRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEIRLEP
P25963 T291 ELM NFKBIA IKBA MAD3 NFKBI QLTLENLQMLPEsEDEEsyDtEsEFTEFtEDELPyDDCVFG
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26196 S475 Sugiyama DDX6 HLR2 RCK TEIKPIPsNIDKSLyVAEyHsEPVEDEKP____________
P27348 S37 Sugiyama YWHAQ ERyDDMAtCMKAVtEQGAELsNEERNLLsVAyKNVVGGRRS
P27695 S290 ELM APEX1 APE APE1 APEX APX HAP1 REF1 MMNARSKNVGWRLDYFLLSHsLLPALCDSKIRSKALGSDHC
P27708 S1069 Sugiyama CAD FKFSRLLDTIGISQPQWRELsDLESARQFCQTVGYPCVVRP
P27824 S554 ELM|Sugiyama CANX EKDKGDEEEEGEEKLEEKQKsDAEEDGGtVsQEEEDRKPKA
P27824 S564 ELM|Sugiyama CANX GEEKLEEKQKsDAEEDGGtVsQEEEDRKPKAEEDEILNRsP
P29401 S105 Sugiyama TKT VWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGsL
P29401 S449 Sugiyama TKT MALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANTKGICF
P29692 S162 Sugiyama EEF1D EF1D AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY
P30305 S186 ELM CDC25B CDC25HU2 ItNsQAPDGRRKsEAGSGAAssSGEDKENDGFVFKMPWKPT
P30305 S187 ELM CDC25B CDC25HU2 tNsQAPDGRRKsEAGSGAAssSGEDKENDGFVFKMPWKPTH
P30533 S247 Sugiyama LRPAP1 A2MRAP KLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWDLAQSA
P30533 T248 Sugiyama LRPAP1 A2MRAP LRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWDLAQSAN
P31327 T1022 Sugiyama CPS1 TLRQLGKKTVVVNCNPETVstDFDECDKLyFEELSLERILD
P32004 S1181 ELM L1CAM CAML1 MIC5 VDsEARPMKDEtFGEyRsLEsDNEEKAFGssQPsLNGDIKP
P32121 T382 SIGNOR|ELM|iPTMNet ARRB2 ARB2 ARR2 APETDVPVDTNLIEFDTNYAtDDDIVFEDFARLRLKGMKDD
P34897 S52 Sugiyama SHMT2 AQTQTGEANRGWtGQEsLsDsDPEMWELLQREKDRQCRGLE
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34932 S415 Sugiyama HSPA4 APG2 HSPH2 TDVVPYPISLRWNsPAEEGssDCEVFSKNHAAPFSKVLTFy
P35221 S641 Sugiyama CTNNA1 GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35222 S29 SIGNOR|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 ELDMAMEPDRKAAVsHWQQQsyLDsGIHsGATtTAPsLsGK
P35222 T102 SIGNOR|ELM|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 IDGQyAMTRAQRVRAAMFPEtLDEGMQIPStQFDAAHPtNV
P35222 T112 SIGNOR|ELM|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 QRVRAAMFPEtLDEGMQIPStQFDAAHPtNVQRLAEPSQML
P35222 T393 ELM CTNNB1 CTNNB OK/SW-cl.35 PRO2286 PsQRLVQNCLWtLRNLSDAAtKQEGMEGLLGTLVQLLGSDD
P35244 S44 Sugiyama RPA3 REPA3 RPA14 PVCFVGRLEKIHPTGKMFILsDGEGKNGTIELMEPLDEEIS
P35568 S24 ELM IRS1 PPEsDGFSDVRKVGYLRKPKsMHKRFFVLRAAsEAGGPARL
P35579 S1943 Sugiyama MYH9 RGDLPFVVPRRMARKGAGDGsDEEVDGKADGAEAKPAE___
P35638 S14 ELM DDIT3 CHOP CHOP10 GADD153 _______MAAESLPFSFGTLssWELEAWYEDLQEVLssDEN
P35638 S15 ELM DDIT3 CHOP CHOP10 GADD153 ______MAAESLPFSFGTLssWELEAWYEDLQEVLssDENG
P35638 S30 ELM DDIT3 CHOP CHOP10 GADD153 FGTLssWELEAWYEDLQEVLssDENGGTYVSPPGNEEEESK
P35638 S31 ELM DDIT3 CHOP CHOP10 GADD153 GTLssWELEAWYEDLQEVLssDENGGTYVSPPGNEEEESKI
P35659 S306 Sugiyama DEK DSSTTKKNQNSSKKEsEsEDssDDEPLIKKLKKPPTDEELK
P35659 S307 Sugiyama DEK SSTTKKNQNSSKKEsEsEDssDDEPLIKKLKKPPTDEELKE
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36915 S51 Sugiyama GNL1 HSR1 RsssNsRSGSRERREEQtDtsDGEsVTHHIRRLNQQPsQGL
P36915 T48 Sugiyama GNL1 HSR1 DGLRsssNsRSGSRERREEQtDtsDGEsVTHHIRRLNQQPs
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37840 S129 iPTMNet SNCA NACP PARK1 QEGILEDMPVDPDNEAyEMPsEEGyQDyEPEA_________
P39023 T305 Sugiyama RPL3 OK/SW-cl.32 YKIGQGyLIKDGKLIKNNAstDyDLSDKSINPLGGFVHYGE
P39687 S158 ELM ANP32A C15orf1 LANP MAPM PHAP1 LLPQLtyLDGyDRDDKEAPDsDAEGYVEGLDDEEEDEDEEE
P39687 S204 ELM ANP32A C15orf1 LANP MAPM PHAP1 QVVEDEEDEDEEEEGEEEDVsGEEEEDEEGYNDGEVDDEED
P41236 S121 SIGNOR|ELM|iPTMNet|Sugiyama PPP1R2 IPP2 ARKLAAAEGLEPKyRIQEQEssGEEDsDLsPEEREKKRQFE
P41236 S122 SIGNOR|ELM|iPTMNet PPP1R2 IPP2 RKLAAAEGLEPKyRIQEQEssGEEDsDLsPEEREKKRQFEM
P41236 S87 SIGNOR|ELM|iPTMNet PPP1R2 IPP2 KIDEPstPYHsMMGDDEDACsDtEAtEAMAPDILARKLAAA
P42166 S66 Sugiyama TMPO LAP2 TARNRPPLPAGTNsKGPPDFssDEEREPtPVLGsGAAAAGR
P42166 S67 Sugiyama TMPO LAP2 ARNRPPLPAGTNsKGPPDFssDEEREPtPVLGsGAAAAGRS
P42166 T74 Sugiyama TMPO LAP2 PAGTNsKGPPDFssDEEREPtPVLGsGAAAAGRSRAAVGRK
P42167 S66 Sugiyama TMPO LAP2 TARNRPPLPAGTNSKGPPDFssDEEREPtPVLGsGAAAAGR
P42167 S67 Sugiyama TMPO LAP2 ARNRPPLPAGTNSKGPPDFssDEEREPtPVLGsGAAAAGRS
P42167 T74 Sugiyama TMPO LAP2 PAGTNSKGPPDFssDEEREPtPVLGsGAAAAGRSRAAVGRK
P42574 S176 Sugiyama CASP3 CPP32 KLFIIQACRGTELDCGIEtDsGVDDDMACHKIPVEADFLYA
P42574 T174 Sugiyama CASP3 CPP32 KPKLFIIQACRGTELDCGIEtDsGVDDDMACHKIPVEADFL
P42768 S483 SIGNOR|iPTMNet WAS IMD2 SEGLVGALMHVMQKRSRAIHssDEGEDQAGDEDEDDEWDD_
P42768 S484 SIGNOR|iPTMNet WAS IMD2 EGLVGALMHVMQKRSRAIHssDEGEDQAGDEDEDDEWDD__
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P45973 S14 Sugiyama CBX5 HP1A _______MGKKTKRtADssssEDEEEyVVEKVLDRRVVKGQ
P46777 S185 Sugiyama RPL5 MSTP030 GAVDGGLsIPHstKRFPGyDsEsKEFNAEVHRKHIMGQNVA
P46777 S187 Sugiyama RPL5 MSTP030 VDGGLsIPHstKRFPGyDsEsKEFNAEVHRKHIMGQNVADy
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46783 T148 Sugiyama RPS10 RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P47712 S437 Sugiyama PLA2G4A CPLA2 PLA2G4 MEEELENIttKHIVsNDssDsDDEsHEPKGtENEDAGsDyQ
P48506 S291 Sugiyama GCLC GLCL GLCLC TICPIVMALSAASPFYRGYVsDIDCRWGVISASVDDRTREE
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P49368 T254 Sugiyama CCT3 CCTG TRIC5 KNPRIVLLDssLEyKKGEsQtDIEITREEDFTRILQMEEEY
P49427 S203 ELM CDC34 UBCH3 UBE2R1 VPTTLAEYCVKTKAPAPDEGsDLFYDDYYEDGEVEEEADsC
P49427 S222 ELM CDC34 UBCH3 UBE2R1 GsDLFYDDYYEDGEVEEEADsCFGDDEDDsGtEEs______
P49427 S231 ELM CDC34 UBCH3 UBE2R1 YEDGEVEEEADsCFGDDEDDsGtEEs_______________
P49427 S236 ELM CDC34 UBCH3 UBE2R1 VEEEADsCFGDDEDDsGtEEs____________________
P49427 T233 ELM CDC34 UBCH3 UBE2R1 DGEVEEEADsCFGDDEDDsGtEEs_________________
P49736 S139 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 QRDREAGRGLGRMRRGLLyDsDEEDEERPARKRRQVERAtE
P49736 T457 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 TVILANHVAKKDNKVAVGELtDEDVKMITSLSKDQQIGEKI
P49795 S151 ELM RGS19 GAIP GNAI3IP NQHVVDEKARLIyEDyVSILsPKEVSLDSRVREGINKKMQE
P49795 S24 SIGNOR|ELM|iPTMNet RGS19 GAIP GNAI3IP PHEAEKQITGPEEADRPPsMssHDTASPAAPSRNPCCLCWC
P49810 S19 ELM PSEN2 AD4 PS2 PSNL2 STM2 __MLTFMAsDsEEEVCDERtsLMsAEsPtPRSCQEGRQGPE
P49810 S335 ELM PSEN2 AD4 PS2 PSNL2 STM2 LQLPYDPEMEEDsYDsFGEPsYPEVFEPPLTGYPGEELEEE
P49810 S7 ELM PSEN2 AD4 PS2 PSNL2 STM2 ______________MLTFMAsDsEEEVCDERtsLMsAEsPt
P49810 S9 ELM PSEN2 AD4 PS2 PSNL2 STM2 ____________MLTFMAsDsEEEVCDERtsLMsAEsPtPR
P50502 S76 Sugiyama ST13 AAG2 FAM10A1 HIP SNC6 KEEKPDSKKVEEDLKADEPssEEsDLEIDKEGVIEPDTDAP
P50502 S79 Sugiyama ST13 AAG2 FAM10A1 HIP SNC6 KPDSKKVEEDLKADEPssEEsDLEIDKEGVIEPDTDAPQEM
P51116 S410 Sugiyama FXR2 FMR1L2 LGFRPPGsGRGsGGsDKAGystDEssSSsLHATRTYGGSYG
P51116 T411 Sugiyama FXR2 FMR1L2 GFRPPGsGRGsGGsDKAGystDEssSSsLHATRTYGGSYGG
P51580 S14 Sugiyama TPMT _______MDGTRTSLDIEEysDtEVQKNQVLTLEEWQDKWV
P51811 S383 ELM XK XKR1 XRG1 ILFMLVFYQFFHPCKKLFSSsVSEGFQRWLRCFCWACRQQK
P51858 S132 Sugiyama HDGF HMG1L2 PEPEPEAAEGDGDKKGNAEGssDEEGKLVIDEPAKEKNEKG
P51858 S133 Sugiyama HDGF HMG1L2 EPEPEAAEGDGDKKGNAEGssDEEGKLVIDEPAKEKNEKGA
P51946 T315 ELM|PSP|Sugiyama CCNH KGYEDDDYVsKKSKHEEEEWtDDDLVEsL____________
P52655 S280 SIGNOR|ELM GTF2A1 TF2A1 AQPAQTQAPLVLQVDGTGDTssEEDEDEEEDYDDDEEEDKE
P52655 S281 SIGNOR|ELM GTF2A1 TF2A1 QPAQTQAPLVLQVDGTGDTssEEDEDEEEDYDDDEEEDKEK
P52655 S316 SIGNOR|ELM GTF2A1 TF2A1 EEDKEKDGAEDGQVEEEPLNsEDDVsDEEGQELFDTENVVV
P52655 S321 SIGNOR|ELM GTF2A1 TF2A1 KDGAEDGQVEEEPLNsEDDVsDEEGQELFDTENVVVCQYDK
P52789 S340 Sugiyama HK2 FGGKLSPELLNTGRFETKDIsDIEGEKDGIRKAREVLMRLG
P53999 S11 ELM SUB1 PC4 RPO2TC1 __________MPKSKELVsssssGsDsDsEVDKKLKRKKQV
P53999 S118 Sugiyama SUB1 PC4 RPO2TC1 PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________
P53999 S13 ELM SUB1 PC4 RPO2TC1 ________MPKSKELVsssssGsDsDsEVDKKLKRKKQVAP
P53999 S15 ELM|Sugiyama SUB1 PC4 RPO2TC1 ______MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEK
P53999 S17 ELM|Sugiyama SUB1 PC4 RPO2TC1 ____MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPV
P53999 S19 ELM SUB1 PC4 RPO2TC1 __MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPVKK
P54105 S102 Sugiyama CLNS1A CLCI ICLN VNAKFEEEsKEPVADEEEEDsDDDVEPITEFRFVPSDKSAL
P54278 S547 Sugiyama PMS2 PMSL2 RGSQEHVDsQEKAPKTDDSFsDVDCHSNQEDTGCKFRVLPQ
P54578 S492 Sugiyama USP14 TGT WHIAYVLLYGPRRVEIMEEEsEQ__________________
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P55042 S214 ELM RRAD RAD DDVPIILVGNKSDLVRSREVsVDEGRACAVVFDCKFIETSA
P55060 S377 Sugiyama CSE1L CAS XPO2 ADEEAFEDNsEEyIRRDLEGsDIDTRRRAACDLVRGLCKFF
P55060 T255 Sugiyama CSE1L CAS XPO2 METWMNNFHTLLTLDNKLLQtDDEEEAGLLELLKSQICDNA
P55081 S116 Sugiyama MFAP1 DVEERLARHRKIVEPEVVGEsDsEVEGDAWRMEREDssEEE
P55081 S118 Sugiyama MFAP1 EERLARHRKIVEPEVVGEsDsEVEGDAWRMEREDssEEEEE
P55081 S132 Sugiyama MFAP1 VVGEsDsEVEGDAWRMEREDssEEEEEEIDDEEIERRRGMM
P55081 S133 Sugiyama MFAP1 VGEsDsEVEGDAWRMEREDssEEEEEEIDDEEIERRRGMMR
P55081 T267 Sugiyama MFAP1 ETKKELEENKRsLAALDALNtDDENDEEEyEAWKVRELKRI
P55087 S276 SIGNOR|ELM AQP4 VEFKRRFKEAFSKAAQQTKGsYMEVEDNRsQVETDDLILKP
P55087 S285 SIGNOR|ELM AQP4 AFSKAAQQTKGsYMEVEDNRsQVETDDLILKPGVVHVIDVD
P55087 S316 SIGNOR|ELM AQP4 PGVVHVIDVDRGEEKKGKDQsGEVLssV_____________
P55957 S64 SIGNOR|ELM|iPTMNet BID LPVLAPQWEGyDELQtDGNRssHsRLGRIEADsEsQEDIIR
P55957 T59 SIGNOR|ELM|iPTMNet BID ALGHELPVLAPQWEGyDELQtDGNRssHsRLGRIEADsEsQ
P56270 S469 ELM MAZ ZNF801 VAAPPTAVGSLsGAEGVPVSsQPLPSQPW____________
P60484 S370 SIGNOR|iPTMNet PTEN MMAC1 TEP1 TVEEPSNPEASSsTSVtPDVsDNEPDHyRYsDttDsDPENE
P60484 S385 SIGNOR|ELM PTEN MMAC1 TEP1 VtPDVsDNEPDHyRYsDttDsDPENEPFDEDQHtQItKV__
P60484 T366 SIGNOR|iPTMNet PTEN MMAC1 TEP1 YFTKTVEEPSNPEASSsTSVtPDVsDNEPDHyRYsDttDsD
P61201 S178 Sugiyama COPS2 CSN2 TRIP15 LYLEREEYGKLQKILRQLHQsCQTDDGEDDLKKGTQLLEIY
P61218 S2 ELM POLR2F POLRF ___________________MsDNEDNFDGDDFDDVEEDEGL
P61244 S11 ELM MAX BHLHD4 __________MsDNDDIEVEsDEEQPRFQSAADKRAHHNAL
P61244 S2 ELM MAX BHLHD4 ___________________MsDNDDIEVEsDEEQPRFQSAA
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P62263 S137 Sugiyama RPS14 PRO2640 RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______
P62269 T60 Sugiyama RPS18 D6S218E YAHVVLRKADIDLTKRAGELtEDEVERVItIMQNPRQYKIP
P62633 S121 Sugiyama CNBP RNF163 ZNF9 CGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRCG
P63104 S37 Sugiyama YWHAZ ERyDDMAACMKsVtEQGAELsNEERNLLsVAyKNVVGARRs
P67870 S2 ELM|PSP CSNK2B CK2N G5A ___________________MsssEEVSWISWFCGLRGNEFF
P67870 S3 ELM|PSP CSNK2B CK2N G5A __________________MsssEEVSWISWFCGLRGNEFFC
P68363 Y451 Sugiyama TUBA1B DyEEVGVDsVEGEGEEEGEEy____________________
P84090 S24 iPTMNet ERH TILLVQPTKRPEGRtyADyEsVNECMEGVCKMYEEHLKRMN
P84090 T18 iPTMNet ERH ___MsHTILLVQPTKRPEGRtyADyEsVNECMEGVCKMYEE
Q00341 S31 Sugiyama HDLBP HBP VGL sFAEHRSGLVPQQIKVAtLNsEEEsDPPtyKDAFPPLPEKA
Q00613 T142 SIGNOR|ELM|PSP HSF1 HSTF1 VSTLKSEDIKIRQDSVTKLLtDVQLMKGKQECMDSKLLAMK
Q01105 S161 Sugiyama SET FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01892 S129 SIGNOR|ELM|iPTMNet SPIB NFASQTLVPPAYAPYPSPVLsEEEDLPLDSPALEVsDsESD
Q01892 S144 SIGNOR|ELM|iPTMNet SPIB PSPVLsEEEDLPLDSPALEVsDsESDEALVAGPEGKGSEAG
Q01892 S146 SIGNOR|ELM|iPTMNet SPIB PVLsEEEDLPLDSPALEVsDsESDEALVAGPEGKGSEAGTR
Q01892 S37 SIGNOR|ELM|iPTMNet SPIB LYPDGVFYDLDSCKHSSYPDsEGAPDSLWDWTVAPPVPAtP
Q02790 T436 Sugiyama FKBP4 FKBP52 ERLAEEENKAKAEAssGDHPtDTEMKEEQKsNtAGsQsQVE
Q02878 T235 Sugiyama RPL6 TXREB1 AyFKKKKLRKPRHQEGEIFDtEKEKYEITEQRKIDQKAVDs
Q02880 S1522 Sugiyama TOP2B DTVPKPKRAPKQKKVVEAVNsDsDsEFGIPKKTTtPKGKGR
Q02880 S1524 Sugiyama TOP2B VPKPKRAPKQKKVVEAVNsDsDsEFGIPKKTTtPKGKGRGA
Q02952 S598 Sugiyama AKAP12 AKAP250 CLEKGLAEVQQDGEAEEGAtsDGEKKREGVtPWAsFKKMVt
Q03135 S88 SIGNOR|ELM|iPTMNet CAV1 CAV FEDVIAEPEGTHsFDGIWKAsFTTFTVTKYWFYRLLSALFG
Q04206 S529 ELM RELA NFKB3 RPPDPAPAPLGAPGLPNGLLsGDEDFSsIADMDFsALLSQI
Q04637 S1430 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI GQDIGAFVAEQKVEyTLGEEsEAPGQRALPsEELNRQLEKL
Q05519 S434 Sugiyama SRSF11 SFRS11 sDKDVKQVtRDyDEEEQGYDsEKEKKEEKKPIEtGsPKtKE
Q05940 S511 SIGNOR|ELM|iPTMNet SLC18A2 SVMT VMAT2 KTKMYTQNNIQSYPIGEDEEsEsD_________________
Q05940 S513 SIGNOR|ELM SLC18A2 SVMT VMAT2 KMYTQNNIQSYPIGEDEEsEsD___________________
Q06413 S59 ELM MEF2C CDCEIALIIFNSTNKLFQYAsTDMDKVLLKYTEYNEPHESR
Q07020 T87 Sugiyama RPL18 IRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRVTS
Q07021 S213 Sugiyama C1QBP GC1QBP HABP1 SF2P32 VGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDSLDW
Q07954 S3642 Sugiyama LRP1 A2MR APR SGHCIPLRWRCDADADCMDGsDEEACGTGVRTCPLDEFQCN
Q08945 S444 Sugiyama SSRP1 FACT80 NIKNRGLKEGMNPsyDEyADsDEDQHDAYLERMKEEGKIRE
Q08AD1 S1148 Sugiyama CAMSAP2 CAMSAP1L1 KIAA1078 LSDLKPPEKADVPVEKYDGEsDKEQFDDDQKVCCGFFFKDD
Q12874 T131 Sugiyama SF3A3 SAP61 EELLKARENPSEEAQNLVEFtDEEGyGRYLDLHDCYLKYIN
Q12972 S204 SIGNOR|ELM PPP1R8 ARD1 NIPP1 EGNLDIQRPKRKRKNsRVtFsEDDEIINPEDVDPSVGRFRN
Q12972 T161 SIGNOR|ELM PPP1R8 ARD1 NIPP1 EKMGGEDDELKGLLGLPEEEtELDNLTEFNTAHNKRIsTLT
Q13017 T1217 Sugiyama ARHGAP5 RHOGAP5 EDPLLsPVETWKGGIDNPAItsDQELDDKKMKKKTHKVKED
Q13033 T293 Sugiyama STRN3 GS2NA SG2NA KDKHRMNKHKIGNEGLAADLtDDPDtEEALKEFDFLVTAED
Q13085 S29 SIGNOR|ELM ACACA ACAC ACC1 ACCA QPLELNQHSRFIIGsVsEDNsEDEISNLVKLDLLEEKEGsL
Q13144 S717 SIGNOR|iPTMNet EIF2B5 EIF2BE LRKNQQLQRFIQWLKEAEEEssEDD________________
Q13144 S718 SIGNOR|iPTMNet EIF2B5 EIF2BE RKNQQLQRFIQWLKEAEEEssEDD_________________
Q13164 S562 Sugiyama MAPK7 BMK1 ERK5 PRKM7 ERGAGASGGPStDPLAGLVLsDNDRsLLERWTRMARPAAPA
Q13347 S302 Sugiyama EIF3I EIF3S2 TRIP1 KGHFGPINSVAFHPDGKSYssGGEDGyVRIHYFDPQYFEFE
Q13351 T23 SIGNOR|ELM KLF1 EKLF TAETALPSISTLTALGPFPDtQDDFLKWWRSEEAQDMGPGP
Q13409 S51 Sugiyama DYNC1I2 DNCI2 DNCIC2 ERKKKETDQKKEAVAPVQEEsDLEKKRREAEALLQSMGLTP
Q13428 S347 Sugiyama TCOF1 AsQTKAGKPEEDSEsSSEEssDsEEETPAAKALLQAKASGK
Q13428 S417 Sugiyama TCOF1 AVAKAQAGKREEDSQSSSEEsDsEEEAPAQAKPSGKAPQVR
Q13428 S87 Sugiyama TCOF1 EDAALQAKKTRVsDPIstsEssEEEEEAEAETAKAtPRLAs
Q13428 S88 Sugiyama TCOF1 DAALQAKKTRVsDPIstsEssEEEEEAEAETAKAtPRLAst
Q13435 S302 Sugiyama SF3B2 SAP145 SRQEEMNsQQEEEEMETDARssLGQsAsEtEEDtVsVsKKE
Q13435 S303 Sugiyama SF3B2 SAP145 RQEEMNsQQEEEEMETDARssLGQsAsEtEEDtVsVsKKEK
Q13435 S309 Sugiyama SF3B2 SAP145 sQQEEEEMETDARssLGQsAsEtEEDtVsVsKKEKNRKRRN
Q13435 T311 Sugiyama SF3B2 SAP145 QEEEEMETDARssLGQsAsEtEEDtVsVsKKEKNRKRRNRK
Q13442 S60 Sugiyama PDAP1 HASPP28 QKEGGDGAAGDPKKEKKsLDsDEsEDEEDDyQQKRKGVEGL
Q13442 S63 Sugiyama PDAP1 HASPP28 GGDGAAGDPKKEKKsLDsDEsEDEEDDyQQKRKGVEGLIDI
Q13541 S112 SIGNOR|iPTMNet|Sugiyama EIF4EBP1 EAsQsHLRNsPEDKRAGGEEsQFEMDI______________
Q13547 S421 SIGNOR|ELM|iPTMNet|Sugiyama HDAC1 RPD3L1 PDKRIsICssDKRIACEEEFsDsEEEGEGGRKNsSNFKKAK
Q13547 S423 SIGNOR|ELM|iPTMNet|Sugiyama HDAC1 RPD3L1 KRIsICssDKRIACEEEFsDsEEEGEGGRKNsSNFKKAKRV
Q13561 Y86 Sugiyama DCTN2 DCTN50 GLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKYQRL
Q13610 S50 Sugiyama PWP1 EEVKRLIAEAKEKLQEEGGGsDEEEtGsPsEDGMQsARTQA
Q13769 S312 Sugiyama THOC5 C22orf19 KIAA0983 GSVDEAKALFKPPEDsQDDEsDsDAEEEQttKRRRPtLGVQ
Q13769 S314 Sugiyama THOC5 C22orf19 KIAA0983 VDEAKALFKPPEDsQDDEsDsDAEEEQttKRRRPtLGVQLD
Q13895 S98 Sugiyama BYSL ENP1 KPAAPRERTTRLGPRMPQDGsDDEDEEWPTLEKAATMTAAG
Q14005 S743 SIGNOR|iPTMNet IL16 NLFSPIMSENHGHMPLQPNAsLNEEEGTQGHPDGtPPKLDT
Q14204 S1313 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 DREKCAKAKEALELtDtGLLsGSEERVQVALEELQDLKGVW
Q14432 S408 Sugiyama PDE3A QAIHKPRVNPVtsLsENytCsDsEESSEKDKLAIPKRLRRs
Q14566 S758 Sugiyama MCM6 EDESALKRSELVNWYLKEIEsEIDsEEELINKKRIIEKVIH
Q14566 S762 Sugiyama MCM6 ALKRSELVNWYLKEIEsEIDsEEELINKKRIIEKVIHRLTH
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14676 S168 Sugiyama MDC1 KIAA0170 NFBD1 EEtPRVQGEtQPQRLLLAEDsEEEVDFLsERRMVKKSRTTS
Q14676 T455 Sugiyama MDC1 KIAA0170 NFBD1 MPQRVVLLQRsQtttERDsDtDVEEEELPVENREAVLKDHT
Q14684 S245 Sugiyama RRP1B KIAA0179 PFVPEETMEEQKtKVGDGDLsAEEIPENEVsLRRAVSKKKT
Q14684 T451 Sugiyama RRP1B KIAA0179 PEASGLKALKARVAEPGAEAtsstGEEsGsEHPPAVPMHNK
Q14694 S576 Sugiyama USP10 KIAA0190 sNGPKNHSVNEEEQEEQGEGsEDEWEQVGPRNKTSVTRQAD
Q15019 S218 Sugiyama SEPTIN2 DIFF6 KIAA0158 NEDD5 SEPT2 RILDEIEEHNIKIyHLPDAEsDEDEDFKEQtRLLKASIPFS
Q15022 S583 SIGNOR SUZ12 CHET9 JJAZ1 KIAA0160 RLYFHsDtCLPLRPQEMEVDsEDEKDPEWLREKTITQIEEF
Q15084 S428 Sugiyama PDIA6 ERP5 P5 TXNDC7 EREPWDGRDGELPVEDDIDLsDVELDDLGKDEL________
Q15084 T166 Sugiyama PDIA6 ERP5 P5 TXNDC7 YSSGKQGRSDsSSKKDVIELtDDsFDKNVLDSEDVWMVEFY
Q15185 S113 Sugiyama PTGES3 P23 TEBP RAKLNWLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGD
Q15293 T100 Sugiyama RCN1 RCN sKERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNV
Q15459 S451 Sugiyama SF3A1 SAP114 IGLLDPRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAE
Q15751 S1521 Sugiyama HERC1 tsPNYRLIKsRsEsDLsQPEsDEEGYALsGRRNVDLDLAAs
Q15785 S45 Sugiyama TOMM34 URCC3 yAEASALyGRALRVLQAQGssDPEEEsVLysNRAACHLKDG
Q15906 S41 ELM VPS72 TCFL1 YL1 LEAEEEDEFYQTTYGGFTEEsGDDEYQGDQsDTEDEVDsDF
Q15906 S51 ELM VPS72 TCFL1 YL1 QTTYGGFTEEsGDDEYQGDQsDTEDEVDsDFDIDEGDEPSs
Q15906 S59 ELM VPS72 TCFL1 YL1 EEsGDDEYQGDQsDTEDEVDsDFDIDEGDEPSsDGEAEEPR
Q15906 S71 ELM VPS72 TCFL1 YL1 sDTEDEVDsDFDIDEGDEPSsDGEAEEPRRKRRVVtKAYKE
Q16543 S13 SIGNOR|ELM|iPTMNet|PSP CDC37 CDC37A ________MVDysVWDHIEVsDDEDEtHPNIDTASLFRWRH
Q16623 S14 SIGNOR|ELM|iPTMNet STX1A STX1 _______MKDRTQELRtAKDsDDDDDVAVTVDRDRFMDEFF
Q16625 S408 ELM OCLN GRSKRTEQDHyEtDyttGGEsCDELEEDWIREYPPItSDQQ
Q16625 T404 ELM OCLN KGRAGRSKRTEQDHyEtDyttGGEsCDELEEDWIREYPPIt
Q16666 S132 ELM IFI16 IFNGIP1 sstVKtEGAEAtPGAQKRKKsTKEKAGPKGsKVsEEQtQPP
Q2T9J0 S171 Sugiyama TYSND1 FGDEAAEQWRFSSAARDDEVsEDEEADQLRALGWFALLGVR
Q32P28 S479 Sugiyama P3H1 GROS1 LEPRE1 PSEC0109 LTMNSKLLNGSQRVVMDGVIsDHECQELQRLTNVAATSGDG
Q4G0J3 S261 Sugiyama LARP7 HDCMA18P MDtsNtsIsKMKRsRPtsEGsDIEstEPQKQCSKKKKKRDR
Q53EL6 S345 Sugiyama PDCD4 H731 NHLVKEIDMLLKEyLLSGDIsEAEHCLKELEVPHFHHELVY
Q53EL6 S80 Sugiyama PDCD4 H731 KRRLRKNssRDsGRGDsVsDsGsDALRSGLtVPtsPKGRLL
Q56P03 S109 Sugiyama EAPP C14orf11 BM-036 sGNGKVATAPTRyYDDIyFDsDsEDEDRAVQVtKKKKKKQH
Q56P03 S111 Sugiyama EAPP C14orf11 BM-036 NGKVATAPTRyYDDIyFDsDsEDEDRAVQVtKKKKKKQHKI
Q58FF7 S205 Sugiyama HSP90AB3P HSP90BC sQFIGyPItLyLEKEQDKEIsDDEAEEEKGEKEEEDKDDEE
Q58FF8 S177 Sugiyama HSP90AB2P HSP90BB GEKEEENKDDEEKPKIEDVGsDEEDDsGKDKKKKTKKIKEK
Q5H9R7 S617 Sugiyama PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 NIALFEACCKERIQQFDDGGsDEEDIWEEKHIAFtPEsQRR
Q5JSH3 S403 Sugiyama WDR44 RPH11 PLTLHIMRRtKEyVsNDAAQsDDEEKLQsQPTDTDGGRLKQ
Q5M775 S241 Sugiyama SPECC1 CYTSB NSP5 DTEPMIRALEEKNKNFQKELsDLEEENRVLKEKLIYLEHSP
Q5T1M5 S1164 Sugiyama FKBP15 KIAA0674 GstVAGAALRPsHHsQRssLsGDEEDELFKGATLKALRPKA
Q5VT52 S374 Sugiyama RPRD2 KIAA0460 HSPC099 EKsAtPEPVtDNRDVEDMELsDVEDDGsKIIVEDRKEKPAE
Q5VZL5 S122 Sugiyama ZMYM4 KIAA0425 ZNF262 VssIHtDDsLEVERRVtQHEsDNENEIQIQNKLKKDFPKQF
Q5VZL5 T118 Sugiyama ZMYM4 KIAA0425 ZNF262 KDNLVssIHtDDsLEVERRVtQHEsDNENEIQIQNKLKKDF
Q68D20 S161 Sugiyama PMS2CL PMS2P13 RGSQEHVDsQEKAPEtDDsFsDVDCHSNQEDTGCKFQVLPQ
Q6FI81 S305 Sugiyama CIAPIN1 CUA001 PRO0915 CAsCPyLGMPAFKPGEKVLLsDsNLHDA_____________
Q6NZY4 T342 Sugiyama ZCCHC8 WLKEAELENsGLALYDGKDGtDGEtEVGEIQQNKSVTYDLS
Q6PD62 T925 Sugiyama CTR9 KIAA0155 SH2BP1 GGGGRRSKKGGEFDEFVNDDtDDDLPIsKKKKRRKGsGsEQ
Q6PKG0 S627 Sugiyama LARP1 KIAA0731 LARP FLFDEEMEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVt
Q6PKG0 S631 Sugiyama LARP1 KIAA0731 LARP EEMEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVtQtPH
Q6PKG0 Y633 Sugiyama LARP1 KIAA0731 LARP MEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVtQtPHyM
Q6VY07 S278 ELM PACS1 KIAA1175 IDHEGIKSKLSDRSPDIDNYsEEEEESFSSEQEGSDDPLHG
Q712K3 S233 SIGNOR|iPTMNet UBE2R2 CDC34B UBC3B DDIDDEDEEEEDADCYDDDDsGNEES_______________
Q71U36 Y451 Sugiyama TUBA1A TUBA3 DyEEVGVDsVEGEGEEEGEEy____________________
Q76FK4 S838 Sugiyama NOL8 C9orf34 NOP132 PGEEWVKESMGKTSGKLFDssDDDEsDsEDDSNRFKIKPQF
Q76FK4 S843 Sugiyama NOL8 C9orf34 NOP132 VKESMGKTSGKLFDssDDDEsDsEDDSNRFKIKPQFEGRAG
Q7Z4V5 S366 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 EKEEKERRRERADRGEAERGsGGssGDELREDDEPVKKRGR
Q7Z4V5 S369 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 EKERRRERADRGEAERGsGGssGDELREDDEPVKKRGRKGR
Q7Z4V5 S370 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 KERRRERADRGEAERGsGGssGDELREDDEPVKKRGRKGRG
Q7Z4V5 S396 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 EDDEPVKKRGRKGRGRGPPsssDsEPEAELEREAKKSAKKP
Q7Z4V5 S399 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 EPVKKRGRKGRGRGPPsssDsEPEAELEREAKKSAKKPQSS
Q7Z6Z7 S1907 Sugiyama HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272 EVANCCIRIALPAPRGsGtAsDDEFENLRIKGPNAVQLVKt
Q86UP2 S77 Sugiyama KTN1 CG1 KIAA0004 AEKKKNKKKEIQNGNLHEsDsEsVPRDFKLSDALAVEDDQV
Q86V81 S239 Sugiyama ALYREF ALY BEF THOC4 tRGGARGRGRGAGRNSKQQLsAEELDAQLDAyNARMDts__
Q86VM9 S34 Sugiyama ZC3H18 NHN1 PEDEEQPQGLsDDDILRDsGsDQDLDGAGVRAsDLEDEEsA
Q86VM9 S46 Sugiyama ZC3H18 NHN1 DDILRDsGsDQDLDGAGVRAsDLEDEEsAARGPsQEEEDNH
Q86WR0 S204 Sugiyama CCDC25 RSYssLMKVENMSSNQDGNDsDEFM________________
Q8IV38 S422 Sugiyama ANKMY2 IsQKDSNPEDSGEGKKEsLEsEAELEGLQDAPAGPQVSEE_
Q8IWA0 S782 Sugiyama WDR75 UTP17 KSAKEIPEDVDMEEEKEsEDsDEENDFTEKVQDtsNtGLGE
Q8IWW6 S215 Sugiyama ARHGAP12 QEQSCDSAGEGSERIHQDSEsGDELSSSsTEQIRAttPPNQ
Q8IYB3 S802 Sugiyama SRRM1 SRM160 PAVPVKKAKsPtPsPsPPRNsDQEGGGKKKKKKKDKKHKKD
Q8IYB3 S874 Sugiyama SRRM1 SRM160 tttLAQEEPVAAPEPKKEtEsEAEDNLDDLEKHLREKALRS
Q8IYB3 T872 Sugiyama SRRM1 SRM160 AAtttLAQEEPVAAPEPKKEtEsEAEDNLDDLEKHLREKAL
Q8IYB7 S875 Sugiyama DIS3L2 FAM6A AILKRPGTQGHLGPEKEEEEsDGEPEDssTS__________
Q8N163 T454 SIGNOR CCAR2 DBC1 KIAA1967 PTLEEWEALCQQKAAEAAPPtQEAQGEtEPTEQAPDALEQA
Q8N6N3 S158 Sugiyama C1orf52 BAG GM117 DAPQNAKKARLLPEGEEtLEsDDEKDEHtsKKRKVEPGEPA
Q8ND56 S374 Sugiyama LSM14A C19orf13 FAM61A RAP55 RAP55A EDPLGPNCYYDKTKsFFDNIsCDDNRERRPtWAEERRLNAE
Q8NE71 S109 Sugiyama ABCF1 ABC50 DDDGEEKELMERLKKLsVPtsDEEDEVPAPKPRGGKKTKGG
Q8NE71 S140 Sugiyama ABCF1 ABC50 PRGGKKTKGGNVFAALIQDQsEEEEEEEKHPPKPAKPEKNR
Q8NE71 T108 Sugiyama ABCF1 ABC50 VDDDGEEKELMERLKKLsVPtsDEEDEVPAPKPRGGKKTKG
Q8NEN9 S496 Sugiyama PDZD8 PDZK8 SGYEEEAAGLTVDTESRELDsEFEDLAsDVRAQNEFKDEAQ
Q8NHW5 S304 Sugiyama RPLP0P6 DTTAAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD_______
Q8NHW5 S307 Sugiyama RPLP0P6 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8WVC0 S66 Sugiyama LEO1 RDL DQDERGDSGQPSNKELFGDDsEDEGAsHHsGSDNHSERSDN
Q8WXI9 S129 Sugiyama GATAD2B KIAA1150 ARRsEPERGRLtPsPDIIVLsDNEAssPRsSsRMEERLKAA
Q92478 S127 Sugiyama CLEC2B AICL CLECSF2 IFNRG1 DGATFTKSFGMRGSEGCAYLsDDGAATARCYTERKWICRKR
Q92598 S509 SIGNOR|iPTMNet HSPH1 HSP105 HSP110 KIAA0201 IFTISTASMVEKVPtEENEMssEADMECLNQRPPENPDTDK
Q92614 S1970 Sugiyama MYO18A CD245 KIAA0216 MYSPDZ TIAF1 NSLQDMVTKYQKRKNKLEGDsDVDsELEDRVDGVKSWLSKN
Q92614 S1974 Sugiyama MYO18A CD245 KIAA0216 MYSPDZ TIAF1 DMVTKYQKRKNKLEGDsDVDsELEDRVDGVKSWLSKNKGPS
Q92626 S1300 Sugiyama PXDN KIAA0230 MG50 PRG2 PXD01 VPO VPO1 NITRVQSDVFRVAEFPHGyGsCDEIPRVDLRVWQDCCEDCR
Q92769 S394 SIGNOR|ELM|Sugiyama HDAC2 LPHAPGVQMQAIPEDAVHEDsGDEDGEDPDKRIsIRAsDKR
Q92769 S422 SIGNOR|ELM|Sugiyama HDAC2 PDKRIsIRAsDKRIACDEEFsDsEDEGEGGRRNVADHKKGA
Q92769 S424 SIGNOR|ELM|Sugiyama HDAC2 KRIsIRAsDKRIACDEEFsDsEDEGEGGRRNVADHKKGAKK
Q92915 S228 SIGNOR FGF14 FHF4 EPSLHDVGETVPKPGVTPsKsTsASAIMNGGKPVNKSKTT_
Q92915 S230 SIGNOR FGF14 FHF4 SLHDVGETVPKPGVTPsKsTsASAIMNGGKPVNKSKTT___
Q92973 S339 Sugiyama TNPO1 KPNB2 MIP1 TRN SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE
Q96B36 S202 Sugiyama AKT1S1 PRAS40 KsLPVSVPVWGFKEKRtEARssDEENGPPssPDLDRIAAsM
Q96B36 S203 Sugiyama AKT1S1 PRAS40 sLPVSVPVWGFKEKRtEARssDEENGPPssPDLDRIAAsMR
Q96C86 T25 Sugiyama DCPS DCS1 HINT5 HSPC015 APQLGKRKRELDVEEAHAAstEEKEAGVGNGTCAPVRLPFS
Q96CW6 S302 Sugiyama SLC7A6OS SRQRMWSKYPLDVQKEFGyDsPHDLDsD_____________
Q96CW6 S308 Sugiyama SLC7A6OS SKYPLDVQKEFGyDsPHDLDsD___________________
Q96D15 T127 Sugiyama RCN3 UNQ239/PRO272 AHTQQRHIRDsVsAAWDtyDtDRDGRVGWEELRNATYGHYA
Q96D46 S468 Sugiyama NMD3 CGI-07 EDEAIRKNVNIyRDsAIPVEsDtDDEGAPRISLAEMLEDLH
Q96D46 T470 Sugiyama NMD3 CGI-07 EAIRKNVNIyRDsAIPVEsDtDDEGAPRISLAEMLEDLHIs
Q96EV2 S205 Sugiyama RBM33 PRR8 LDEFTGGMETLELQKDIKEEsDEEEEDDEEsGRLRFKTERK
Q96I25 S155 Sugiyama RBM17 SPF45 EKRRKDRHEASGFARRPDPDsDEDEDYERERRKRsMGGAAI
Q96KC8 S479 Sugiyama DNAJC1 HTJ1 PEEKSRAKRQKDFDIAEQNEssDEEsLRKERARsAEEPWTQ
Q96KC8 S480 Sugiyama DNAJC1 HTJ1 EEKSRAKRQKDFDIAEQNEssDEEsLRKERARsAEEPWTQN
Q96MW1 T139 Sugiyama CCDC43 MVSEEEKQRKAALLAQyADVtDEEDEADEKDDsGAttMNIG
Q96NB3 S351 Sugiyama ZNF830 CCDC16 KLKEILTIKELQKKEEENADsDDEGELQDLLSQDWRVKGAL
Q96QK1 S759 Sugiyama VPS35 MEM3 TCCCTA00141 TIQVLNQLIQKIREDLPNLEssEEtEQINKHFHNtLEHLRL
Q96S55 S436 Sugiyama WRNIP1 WHIP SSSEPAMFIEDKAVDTLAYLsDGDARAGLNGLQLAVLARLS
Q96S59 T596 Sugiyama RANBP9 RANBPM SSNGFLNGSSKHDHEMEDCDtEMEVDSsQLRRQLCGGsQAA
Q96S90 S99 Sugiyama LYSMD1 SB145 KKTLYIPILTEPRDLFNGLDsEEEKDGEEKVHPSNSEVWPH
Q96SB4 S51 PSP SRPK1 RGsAPHSESDLPEQEEEILGsDDDEQEDPNDYCKGGYHLVK
Q96SB4 S555 PSP SRPK1 WSTACMAFELATGDYLFEPHsGEEYTRDEDHIALIIELLGK
Q96ST2 S398 Sugiyama IWS1 IWS1L DEDEKEGEEEKVAKRKAAVLsDsEDEEKAsAKKSRVVsDAD
Q96ST2 S415 Sugiyama IWS1 IWS1L AVLsDsEDEEKAsAKKSRVVsDADDsDsDAVsDKsGKREKt
Q96ST2 S420 Sugiyama IWS1 IWS1L sEDEEKAsAKKSRVVsDADDsDsDAVsDKsGKREKtIAsDs
Q96ST2 S422 Sugiyama IWS1 IWS1L DEEKAsAKKSRVVsDADDsDsDAVsDKsGKREKtIAsDsEE
Q96T88 S91 Sugiyama UHRF1 ICBP90 NP95 RNF106 LLVRQsLVLPHSTKERDsELsDtDsGCCLGQSESDKsstHG
Q99250 S1112 SIGNOR SCN2A HBA NAC2 SCN2A1 SCN2A2 YMSFINNPSLTVTVPIAVGEsDFENLNTEEFSsEsDMEESK
Q99250 S1124 SIGNOR SCN2A HBA NAC2 SCN2A1 SCN2A2 TVPIAVGEsDFENLNTEEFSsEsDMEESKEKLNATSSSEGS
Q99250 S1126 SIGNOR SCN2A HBA NAC2 SCN2A1 SCN2A2 PIAVGEsDFENLNTEEFSsEsDMEESKEKLNATSSSEGSTV
Q99523 S825 Sugiyama SORT1 DGVDALDtAsHtNKsGYHDDsDEDLLE______________
Q99543 S60 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 KRRNRNAsAsFQELEDKKELsEEsEDEELQLEEFPMLKTLD
Q99543 S63 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 NRNAsAsFQELEDKKELsEEsEDEELQLEEFPMLKTLDPKD
Q99613 S39 Sugiyama EIF3C EIF3S8 GEELVTKPVGGNyGKQPLLLsEDEEDTKRVVRSAKDKRFEE
Q99614 S90 Sugiyama TTC1 TPR1 FEEEPGADKVENKsNEDVNssELDEEyLIELEKNMSDEEKQ
Q99733 S121 Sugiyama NAP1L4 NAP2 PLFDKRREFItGDVEPtDAEsEWHsENEEEEKLAGDMKSKV
Q99733 S125 Sugiyama NAP1L4 NAP2 KRREFItGDVEPtDAEsEWHsENEEEEKLAGDMKSKVVVTE
Q99733 T117 Sugiyama NAP1L4 NAP2 ALyQPLFDKRREFItGDVEPtDAEsEWHsENEEEEKLAGDM
Q99801 T89 SIGNOR|PSP NKX3-1 NKX3.1 NKX3A AGAQNDQLSTGPRAAPEEAEtLAEtEPERHLGSYLLDSENT
Q99801 T93 SIGNOR|PSP NKX3-1 NKX3.1 NKX3A NDQLSTGPRAAPEEAEtLAEtEPERHLGSYLLDSENTSGAL
Q9BPX3 S674 Sugiyama NCAPG CAPG NYMEL3 IEPFKTKKIKTLHCEGtEINsDDEQEsKEVEETATAKNVLK
Q9BQA1 S185 Sugiyama WDR77 MEP50 WD45 HKMT1069 Nbla10071 AHAAQVTCVAAsPHKDSVFLsCSEDNRILLWDTRCPKPASQ
Q9BQE3 S439 Sugiyama TUBA1C TUBA6 SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BRS2 S21 Sugiyama RIOK1 RIO1 MDYRRLLMSRVVPGQFDDADssDsENRDLKTVKEKDDILFE
Q9BRS2 S22 Sugiyama RIOK1 RIO1 DYRRLLMSRVVPGQFDDADssDsENRDLKTVKEKDDILFED
Q9BTC0 S154 Sugiyama DIDO1 C20orf158 DATF1 KIAA0333 ERPASSEKVKGGDDHDDtsDsDsDGLTLKELQNRLRRKREQ
Q9BUJ2 T534 Sugiyama HNRNPUL1 E1BAP5 HNRPUL1 QRRKMRPFEGFQRKAIVICPtDEDLKDRTIKRTDEEGKDVP
Q9BUL5 S315 Sugiyama PHF23 PADSESKEVGsTETSQDGDAsssEGEMRVMDEDIMVESGDD
Q9BVJ6 S29 Sugiyama UTP14A SDCCAG16 sLLALsQQEELADLPKDyLLsEsEDEGDNDGERKHQKLLEA
Q9BVJ6 S31 Sugiyama UTP14A SDCCAG16 LALsQQEELADLPKDyLLsEsEDEGDNDGERKHQKLLEAIs
Q9BW91 S343 Sugiyama NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771 SHSQFIKLVAEKRDAHWSEDsEADCHAL_____________
Q9BYW2 S1413 Sugiyama SETD2 HIF1 HYPB KIAA1732 KMT3A SET2 HSPC069 LEKNDIKDRGPLKKRRQEIEsDsEsDGELQDRKKVRVEVEQ
Q9BYW2 S1417 Sugiyama SETD2 HIF1 HYPB KIAA1732 KMT3A SET2 HSPC069 DIKDRGPLKKRRQEIEsDsEsDGELQDRKKVRVEVEQGETS
Q9BYX2 S920 Sugiyama TBC1D2 PARIS1 PP8997 TBC1D2A KAEyLERRASRRRAVsEGCAsEDEVEGEA____________
Q9BZI7 T169 Sugiyama UPF3B RENT3B UPF3X TKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIEAKN
Q9GZL7 T221 Sugiyama WDR12 GTKFCsGSWDKMLKIWStVPtDEEDEMEEsTNRPRKKQKTE
Q9H0D6 S499 Sugiyama XRN2 sFtsDGsPsPLGGIKRKAEDsDsEPEPEDNVRLWEAGWKQR
Q9H0D6 S501 Sugiyama XRN2 tsDGsPsPLGGIKRKAEDsDsEPEPEDNVRLWEAGWKQRYY
Q9H1E3 S113 Sugiyama NUCKS1 NUCKS JC7 RQAASKAASKQREMLMEDVGsEEEQEEEDEAPFQEKDsGsD
Q9H1E3 S132 Sugiyama NUCKS1 NUCKS JC7 GsEEEQEEEDEAPFQEKDsGsDEDFLMEDDDDsDyGSsKKK
Q9H1E3 S144 Sugiyama NUCKS1 NUCKS JC7 PFQEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPER
Q9H2G2 S347 Sugiyama SLK KIAA0204 STK2 tENsLPIPAsKRAssDLsIAssEEDKLsQNACILEsVSEKt
Q9H2P0 S953 Sugiyama ADNP ADNP1 KIAA0784 GSKYETIHLTEEPTKLMHNAsDsEVDQDDVVEWKDGAsPsE
Q9H2P0 S955 Sugiyama ADNP ADNP1 KIAA0784 KYETIHLTEEPTKLMHNAsDsEVDQDDVVEWKDGAsPsESG
Q9H307 S347 Sugiyama PNN DRS MEMA NDVEIEEAGEEEEKEIAIVHsDAEKEQEEEEQKQEMEVKME
Q9H501 S75 Sugiyama ESF1 ABTAP C20orf6 HDCMC28P KRGRPISHSTTEDLKRFyDLsDsDsNLsGEDSKALSQKKIK
Q9H6Y2 S14 Sugiyama WDR55 _______MDRTCEERPAEDGsDEEDPDsMEAPTRIRDtPED
Q9H6Z4 S108 Sugiyama RANBP3 FPRELAGRsAGGssPEGGEDsDREDGNyCPPVKRERtssLt
Q9HCN4 S338 Sugiyama GPN1 MBDIN RPAP4 XAB1 HUSSY-23 HPsDLILtRGTLDEEDEEADsDtDDIDHRVTEESHEEPAFQ
Q9NPQ8 S436 Sugiyama RIC8A AAGLLAARGLMAGGRPEGQysEDEDtDtDEyKEAKAsINPV
Q9NPQ8 T441 Sugiyama RIC8A AARGLMAGGRPEGQysEDEDtDtDEyKEAKAsINPVTGRVE
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ39 T159 Sugiyama RPS10P5 RPS10L RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9NQ55 S359 Sugiyama PPAN BXDC3 SSF1 QREAHRKKSLEGMKKARVGGsDEEAsGIPsRTASLELGEDD
Q9NQB0 S58 SIGNOR|ELM TCF7L2 TCF4 ERDLADVKSSLVNESEtNQNsssDSEAERRPPPRSESFRDK
Q9NQB0 S59 SIGNOR|ELM TCF7L2 TCF4 RDLADVKSSLVNESEtNQNsssDSEAERRPPPRSESFRDKS
Q9NQB0 S60 SIGNOR|ELM TCF7L2 TCF4 DLADVKSSLVNESEtNQNsssDSEAERRPPPRSESFRDKSR
Q9NR28 S230 Sugiyama DIABLO SMAC EAQIEELRQKTQEEGEERAEsEQEAyLRED___________
Q9NTJ3 S27 Sugiyama SMC4 CAPC SMC4L1 QPSTARRREEGPPPPsPDGAssDAEPEPPsGRtEsPAtAAE
Q9NVU7 S585 Sugiyama SDAD1 NUC130 RKELDAAPGKSQKRKyIEIDsDEEPRGELLsLRDIERLHKK
Q9NXG2 S86 Sugiyama THUMPD1 NEYGDDMYGPEKFtDKDQQPsGsEGEDDDAEAALKKEVGDI
Q9NXG2 S88 Sugiyama THUMPD1 YGDDMYGPEKFtDKDQQPsGsEGEDDDAEAALKKEVGDIKA
Q9NYF8 S385 Sugiyama BCLAF1 BTF KIAA0164 GSEKGRAEGEWEDQEALDyFsDKEsGKQKFNDsEGDDtEEt
Q9NZV7 S155 Sugiyama ZIM2 ZNF656 LAQDSVPAEKRNTEMLDNLPsAGsQFPDFKHLGTFLVFEEL
Q9NZV7 S158 Sugiyama ZIM2 ZNF656 DSVPAEKRNTEMLDNLPsAGsQFPDFKHLGTFLVFEELVTF
Q9P258 S50 Sugiyama RCC2 KIAA1470 TD60 GPAGRKRERPERCssssGGGssGDEDGLELDGAPGGGKRAA
Q9P258 S51 Sugiyama RCC2 KIAA1470 TD60 PAGRKRERPERCssssGGGssGDEDGLELDGAPGGGKRAAR
Q9P2I0 S419 Sugiyama CPSF2 CPSF100 KIAA1367 EKLKKEAAKKLEQSKEADIDssDEsDIEEDIDQPSAHKTKH
Q9P2I0 S420 Sugiyama CPSF2 CPSF100 KIAA1367 KLKKEAAKKLEQSKEADIDssDEsDIEEDIDQPSAHKTKHD
Q9P2I0 S423 Sugiyama CPSF2 CPSF100 KIAA1367 KEAAKKLEQSKEADIDssDEsDIEEDIDQPSAHKTKHDLMM
Q9UBE0 S12 Sugiyama SAE1 AOS1 SUA1 UBLE1A _________MVEKEEAGGGIsEEEAAQyDRQIRLWGLEAQK
Q9UBF6 T10 ELM RNF7 RBX2 ROC2 SAG ___________MADVEDGEEtCALAsHsGssGsKSGGDKMF
Q9UBS4 S78 Sugiyama DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080 PDDPQAQEKFQDLGAAyEVLsDSEKRKQyDTyGEEGLKDGH
Q9UD71 S102 SIGNOR PPP1R1B DARPP32 VQRIAESHLQSIsNLNENQAsEEEDELGELRELGYPREEDE
Q9UD71 S45 SIGNOR PPP1R1B DARPP32 VEMIRRRRPtPAMLFRLsEHssPEEEAsPHQRASGEGHHLK
Q9UD71 S66 iPTMNet PPP1R1B DARPP32 sPEEEAsPHQRASGEGHHLKsKRPNPCAYtPPSLKAVQRIA
Q9UDY2 S430 Sugiyama TJP2 X104 ZO2 sNRsFsPEERRHQysDyDyHsssEKLKERPssREDtPSRLS
Q9UH62 S61 Sugiyama ARMCX3 ALEX3 BM-017 UNQ2517/PRO6007 GGsGDVDDAGDCsGARyNDWsDDDDDsNESKsIVWYPPWAR
Q9UHI6 S652 Sugiyama DDX20 DP103 GEMIN3 RNKVIEQRVPVLASSsQsGDsEsDSDSySSRTSSQSKGNKs
Q9UHI6 S654 Sugiyama DDX20 DP103 GEMIN3 KVIEQRVPVLASSsQsGDsEsDSDSySSRTSSQSKGNKsyL
Q9UHX1 S238 Sugiyama PUF60 FIR ROBPI SIAHBP1 LAEEARAFNRIyVAsVHQDLsDDDIKSVFEAFGKIKSCTLA
Q9UKS6 S276 Sugiyama PACSIN3 SSSEKFHELHRDLHQGIEAAsDEEDLRWWRSTHGPGMAMNW
Q9UKX7 S52 Sugiyama NUP50 NPAP60L PRO1146 EEVLKNRAIKKAKRRNVGFEsDtGGAFKGFKGLVVPSGGGR
Q9UKY7 S107 Sugiyama CDV3 H41 ELEQKEVDysGLRVQAMQIssEKEEDDNEKRQDPGDNWEEG
Q9UNN4 S356 SIGNOR|ELM|iPTMNet GTF2A1L ALF GTF2A1LF IRVTDDDIGEIIQVDGSGDTssNEEIGSTRDADENEFLGNI
Q9UNN4 S357 SIGNOR|ELM|iPTMNet GTF2A1L ALF GTF2A1LF RVTDDDIGEIIQVDGSGDTssNEEIGSTRDADENEFLGNID
Q9UNN4 S418 SIGNOR|ELM|iPTMNet GTF2A1L ALF GTF2A1LF TNSSDNEDPQVNIVEEDPLNsGDDVsEQDVPDLFDTDNVIV
Q9UNN4 S423 SIGNOR|ELM|iPTMNet GTF2A1L ALF GTF2A1LF NEDPQVNIVEEDPLNsGDDVsEQDVPDLFDTDNVIVCQYDK
Q9UNN5 S289 ELM FAF1 UBXD12 UBXN3A CGI-03 ssPAQTREQSEEQITDVHMVsDsDGDDFEDATEFGVDDGEV
Q9UNN5 S291 ELM FAF1 UBXD12 UBXN3A CGI-03 PAQTREQSEEQITDVHMVsDsDGDDFEDATEFGVDDGEVFG
Q9UPR3 S480 Sugiyama SMG5 EST1B KIAA1089 RRRRHPPKVGDDSDLsEGFEsDSSHDSARASEGSDSGSDKS
Q9UQ88 S265 Sugiyama CDK11A CDC2L2 CDC2L3 PITSLREB APAQKPAQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSA
Q9UQ88 S271 Sugiyama CDK11A CDC2L2 CDC2L3 PITSLREB AQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSAESGSGS
Q9UQE7 S1067 SIGNOR|PSP SMC3 BAM BMH CSPG6 SMC3L1 LVPGGKATLVMKKGDVEGsQsQDEGEGsGEsERGsGsQssV
Q9Y237 S19 ELM PIN4 __MPPKGKSGSGKAGKGGAAsGSDSADKKAQGPKGGGNAVK
Q9Y266 S277 Sugiyama NUDC LVssDPEINtKKINPENsKLsDLDsEtRsMVEKMMYDQRQK
Q9Y2B0 S116 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 IDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKFA
Q9Y2X3 S502 Sugiyama NOP58 NOL5 NOP5 HSPC120 TsVKKKKKRGKKKHIKEEPLsEEEPCtstAIAsPEKKKKKK
Q9Y3F4 S254 Sugiyama STRAP MAWD UNRIP EKEFLVAGGEDFKLyKyDyNsGEELEsyKGHFGPIHCVRFS
Q9Y3P9 T996 Sugiyama RABGAP1 HSPC094 FNKEGRVKGISSTKEVLDEDtDEEKETLKNQLREMELELAQ
Q9Y3T9 S672 Sugiyama NOC2L NIR KMADRKDEDRKQFKDLFDLNssEEDDtEGFsERGILRPLSt
Q9Y3T9 S673 Sugiyama NOC2L NIR MADRKDEDRKQFKDLFDLNssEEDDtEGFsERGILRPLStR
Q9Y5B0 S575 SIGNOR|ELM|iPTMNet CTDP1 FCP1 ETESQNSELSGVTAGESLDQsMEEEEEEDtDEDDHLIYLEE
Q9Y5B0 S740 SIGNOR|ELM|iPTMNet CTDP1 FCP1 KVEEQLFPLRDDHTKAQRENsPAAFPDREGVPPTALFHPMP
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y696 S236 Sugiyama CLIC4 GIWRYLtNAysRDEFtNtCPsDKEVEIAysDVAKRLTK___
Q9Y696 S27 Sugiyama CLIC4 LNGLKEEDKEPLIELFVKAGsDGEsIGNCPFSQRLFMILWL
Q9Y6X9 S743 Sugiyama MORC2 KIAA0852 ZCWCC1 tEsPIKLsPAtPsRKRsVAVsDEEEVEEEAERRKERCKRGR
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.994125e-10 9.700 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.124462e-08 7.949 0 0
Chromatin organization R-HSA-4839726 9.040058e-09 8.044 0 0
Chromatin modifying enzymes R-HSA-3247509 6.883298e-09 8.162 0 0
mRNA Splicing R-HSA-72172 2.218657e-08 7.654 0 0
Metabolism of RNA R-HSA-8953854 2.601576e-07 6.585 0 0
DNA Repair R-HSA-73894 6.052227e-06 5.218 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.913120e-05 4.718 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 2.618933e-05 4.582 0 0
Cell Cycle R-HSA-1640170 3.450798e-05 4.462 1 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.261280e-04 3.899 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.709437e-04 3.767 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.744934e-04 3.758 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.690528e-04 3.772 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.108327e-04 3.676 0 0
Epigenetic regulation of gene expression R-HSA-212165 2.199055e-04 3.658 0 0
Regulation of PTEN gene transcription R-HSA-8943724 2.574878e-04 3.589 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.489679e-04 3.604 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 3.423549e-04 3.466 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 5.993420e-04 3.222 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 9.762785e-04 3.010 0 0
Homology Directed Repair R-HSA-5693538 1.179369e-03 2.928 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.314560e-03 2.881 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.992209e-03 2.701 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 2.363751e-03 2.626 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 2.250071e-03 2.648 0 0
Notch-HLH transcription pathway R-HSA-350054 2.453657e-03 2.610 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.429495e-03 2.614 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 2.366986e-03 2.626 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.515524e-03 2.599 0 0
Resolution of D-Loop Structures R-HSA-5693537 2.862170e-03 2.543 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.911856e-03 2.536 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 3.383903e-03 2.471 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 3.368248e-03 2.473 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 3.342826e-03 2.476 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 3.437545e-03 2.464 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 3.437545e-03 2.464 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 3.603185e-03 2.443 0 0
Deubiquitination R-HSA-5688426 3.628123e-03 2.440 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 3.392410e-03 2.469 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.663967e-03 2.436 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 4.284638e-03 2.368 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 4.284638e-03 2.368 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 4.284638e-03 2.368 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 4.284638e-03 2.368 0 0
PKMTs methylate histone lysines R-HSA-3214841 4.022373e-03 2.396 0 0
MITF-M-dependent gene expression R-HSA-9856651 4.229662e-03 2.374 0 0
Apoptotic execution phase R-HSA-75153 3.861958e-03 2.413 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 4.460403e-03 2.351 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 4.633264e-03 2.334 0 0
Regulation of TP53 Activity R-HSA-5633007 5.085502e-03 2.294 1 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 5.480514e-03 2.261 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 5.765120e-03 2.239 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 7.978387e-03 2.098 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 7.978387e-03 2.098 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 7.978387e-03 2.098 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 6.725651e-03 2.172 0 0
Oncogenic MAPK signaling R-HSA-6802957 7.338972e-03 2.134 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 6.506104e-03 2.187 0 0
Cell Cycle, Mitotic R-HSA-69278 6.160025e-03 2.210 1 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 6.950453e-03 2.158 1 1
Signaling by ALK R-HSA-201556 7.843876e-03 2.105 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 6.950453e-03 2.158 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 6.950453e-03 2.158 0 0
mRNA 3'-end processing R-HSA-72187 8.899012e-03 2.051 0 0
Nucleotide Excision Repair R-HSA-5696398 9.001461e-03 2.046 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 9.148611e-03 2.039 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 9.235776e-03 2.035 0 0
HATs acetylate histones R-HSA-3214847 9.329270e-03 2.030 0 0
PTEN Regulation R-HSA-6807070 9.831405e-03 2.007 1 0
Diseases of DNA repair R-HSA-9675135 9.713962e-03 2.013 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.011885e-02 1.995 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.046853e-02 1.980 0 0
Gene expression (Transcription) R-HSA-74160 1.076911e-02 1.968 1 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 1.122816e-02 1.950 0 0
Cellular response to heat stress R-HSA-3371556 1.149230e-02 1.940 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.207833e-02 1.918 0 0
HIV Life Cycle R-HSA-162587 1.249806e-02 1.903 0 0
HDACs deacetylate histones R-HSA-3214815 1.285667e-02 1.891 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.434318e-02 1.843 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.434318e-02 1.843 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 1.434318e-02 1.843 0 0
HDMs demethylate histones R-HSA-3214842 1.434318e-02 1.843 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.431524e-02 1.844 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.392017e-02 1.856 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.395610e-02 1.855 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.437267e-02 1.842 0 0
rRNA processing R-HSA-72312 1.610596e-02 1.793 0 0
G0 and Early G1 R-HSA-1538133 1.613306e-02 1.792 0 0
SDK interactions R-HSA-373756 1.761064e-02 1.754 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.786222e-02 1.748 1 1
DNA Damage Recognition in GG-NER R-HSA-5696394 2.156386e-02 1.666 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.971027e-02 1.705 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 2.241544e-02 1.649 0 0
snRNP Assembly R-HSA-191859 2.008956e-02 1.697 0 0
Metabolism of non-coding RNA R-HSA-194441 2.008956e-02 1.697 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.008956e-02 1.697 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.272571e-02 1.643 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.272571e-02 1.643 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.272571e-02 1.643 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 2.241544e-02 1.649 0 0
Disorders of Developmental Biology R-HSA-9675151 2.062630e-02 1.686 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 1.870586e-02 1.728 0 0
Signaling by RAS mutants R-HSA-6802949 2.272571e-02 1.643 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.984169e-02 1.702 0 0
Signaling by ALK in cancer R-HSA-9700206 1.984169e-02 1.702 0 0
G2/M DNA damage checkpoint R-HSA-69473 2.108329e-02 1.676 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 2.203983e-02 1.657 1 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 2.203983e-02 1.657 1 0
G2/M Checkpoints R-HSA-69481 1.937567e-02 1.713 0 0
Activation of ATR in response to replication stress R-HSA-176187 1.870586e-02 1.728 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 2.018643e-02 1.695 0 0
Disorders of Nervous System Development R-HSA-9697154 2.387456e-02 1.622 0 0
Pervasive developmental disorders R-HSA-9005895 2.387456e-02 1.622 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 2.387456e-02 1.622 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 2.468429e-02 1.608 0 0
Nuclear import of Rev protein R-HSA-180746 2.472244e-02 1.607 0 0
Signaling by Hippo R-HSA-2028269 2.512500e-02 1.600 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 2.641568e-02 1.578 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 2.985376e-02 1.525 0 0
Ephrin signaling R-HSA-3928664 3.023383e-02 1.520 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 3.023383e-02 1.520 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 3.099065e-02 1.509 0 0
M Phase R-HSA-68886 3.105759e-02 1.508 1 0
IRS activation R-HSA-74713 3.435616e-02 1.464 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 3.401519e-02 1.468 0 0
Unwinding of DNA R-HSA-176974 3.401519e-02 1.468 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 3.246682e-02 1.489 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 3.614319e-02 1.442 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 3.669844e-02 1.435 0 0
Cell Cycle Checkpoints R-HSA-69620 3.789541e-02 1.421 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 4.443215e-02 1.352 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 4.237998e-02 1.373 0 0
Regulation of endogenous retroelements R-HSA-9842860 4.027142e-02 1.395 0 0
DNA Double Strand Break Response R-HSA-5693606 4.308499e-02 1.366 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 4.340634e-02 1.362 0 0
Mitotic Prometaphase R-HSA-68877 4.156803e-02 1.381 1 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 4.064075e-02 1.391 0 0
Protein ubiquitination R-HSA-8852135 4.435337e-02 1.353 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.435337e-02 1.353 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.735127e-02 1.325 0 0
Intracellular signaling by second messengers R-HSA-9006925 4.779804e-02 1.321 1 0
Interactions of Vpr with host cellular proteins R-HSA-176033 5.073597e-02 1.295 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 5.073597e-02 1.295 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 5.092966e-02 1.293 0 0
Interaction between L1 and Ankyrins R-HSA-445095 5.142141e-02 1.289 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 5.160867e-02 1.287 0 0
Ub-specific processing proteases R-HSA-5689880 5.406270e-02 1.267 0 0
ChREBP activates metabolic gene expression R-HSA-163765 5.410851e-02 1.267 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 6.202180e-02 1.207 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 5.857837e-02 1.232 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 5.857837e-02 1.232 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 5.970159e-02 1.224 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.876563e-02 1.231 0 0
Membrane Trafficking R-HSA-199991 6.388023e-02 1.195 0 0
Cell-cell junction organization R-HSA-421270 5.848601e-02 1.233 1 0
NRAGE signals death through JNK R-HSA-193648 6.202180e-02 1.207 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 6.102963e-02 1.214 1 0
trans-Golgi Network Vesicle Budding R-HSA-199992 6.444569e-02 1.191 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 6.487637e-02 1.188 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 6.545238e-02 1.184 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 6.565793e-02 1.183 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 6.610528e-02 1.180 1 1
Nuclear Envelope Breakdown R-HSA-2980766 6.750586e-02 1.171 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 6.874482e-02 1.163 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 6.943310e-02 1.158 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 8.078190e-02 1.093 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 8.078190e-02 1.093 0 0
Regulation of PTEN localization R-HSA-8948747 8.078190e-02 1.093 0 0
Recycling of eIF2:GDP R-HSA-72731 8.078190e-02 1.093 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 7.936245e-02 1.100 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 7.392200e-02 1.131 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 7.168876e-02 1.145 0 0
AURKA Activation by TPX2 R-HSA-8854518 7.427250e-02 1.129 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 8.014829e-02 1.096 0 0
RNA Polymerase III Transcription R-HSA-74158 7.168876e-02 1.145 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 7.917327e-02 1.101 0 0
Repression of WNT target genes R-HSA-4641265 7.936245e-02 1.100 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 7.936245e-02 1.100 0 0
S Phase R-HSA-69242 7.977028e-02 1.098 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 7.116436e-02 1.148 1 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 7.930461e-02 1.101 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 7.930461e-02 1.101 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 9.542946e-02 1.020 0 0
PDGFR mutants bind TKIs R-HSA-9674428 9.542946e-02 1.020 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 9.542946e-02 1.020 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 9.542946e-02 1.020 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 9.542946e-02 1.020 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 9.542946e-02 1.020 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 9.542946e-02 1.020 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 9.062339e-02 1.043 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 9.062339e-02 1.043 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 9.383033e-02 1.028 0 0
Long-term potentiation R-HSA-9620244 9.511202e-02 1.022 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 8.253027e-02 1.083 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 8.253027e-02 1.083 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 8.578700e-02 1.067 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 8.578700e-02 1.067 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 8.578700e-02 1.067 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 8.578700e-02 1.067 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 8.578700e-02 1.067 0 0
Signaling by NOTCH1 R-HSA-1980143 8.587988e-02 1.066 0 0
DNA strand elongation R-HSA-69190 9.168980e-02 1.038 0 0
Clathrin-mediated endocytosis R-HSA-8856828 9.454720e-02 1.024 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 8.439523e-02 1.074 0 0
HIV Infection R-HSA-162906 9.028429e-02 1.044 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 9.062339e-02 1.043 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 9.062339e-02 1.043 0 0
Cell junction organization R-HSA-446728 8.362289e-02 1.078 1 0
Adherens junctions interactions R-HSA-418990 8.959069e-02 1.048 1 0
Cell-Cell communication R-HSA-1500931 9.041114e-02 1.044 1 0
ESR-mediated signaling R-HSA-8939211 9.433798e-02 1.025 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 8.271758e-02 1.082 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 8.318786e-02 1.080 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 9.592317e-02 1.018 0 0
Specification of the neural plate border R-HSA-9834899 9.659939e-02 1.015 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 9.827690e-02 1.008 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.013944e-01 0.994 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.013944e-01 0.994 0 0
Nuclear RNA decay R-HSA-9930044 1.013944e-01 0.994 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 1.029433e-01 0.987 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.035519e-01 0.985 1 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.059193e-01 0.975 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.096487e-01 0.960 1 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.817572e-01 0.741 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.817572e-01 0.741 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.817572e-01 0.741 0 0
Impaired BRCA2 translocation to the nucleus R-HSA-9709275 1.817572e-01 0.741 0 0
UNC93B1 deficiency - HSE R-HSA-5602415 1.817572e-01 0.741 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.817572e-01 0.741 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 1.817572e-01 0.741 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.817572e-01 0.741 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.817572e-01 0.741 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.817572e-01 0.741 0 0
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198 1.817572e-01 0.741 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.817572e-01 0.741 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 1.224539e-01 0.912 0 0
Regulation of gap junction activity R-HSA-191650 1.224539e-01 0.912 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 1.224539e-01 0.912 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 1.224539e-01 0.912 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.598509e-01 0.585 0 0
Defective TPMT causes TPMT deficiency R-HSA-5578995 2.598509e-01 0.585 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.598509e-01 0.585 0 0
Defective CD320 causes MMATC R-HSA-3359485 2.598509e-01 0.585 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.598509e-01 0.585 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.598509e-01 0.585 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.564929e-01 0.806 0 0
Calcineurin activates NFAT R-HSA-2025928 1.212088e-01 0.916 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 1.920298e-01 0.717 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 1.920298e-01 0.717 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 1.920298e-01 0.717 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 3.304955e-01 0.481 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 3.304955e-01 0.481 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 3.304955e-01 0.481 0 0
HHAT G278V doesn't palmitoylate Hh-Np R-HSA-5658034 3.304955e-01 0.481 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 3.304955e-01 0.481 0 0
2-LTR circle formation R-HSA-164843 1.436973e-01 0.843 0 0
Autointegration results in viral DNA circles R-HSA-177539 2.284690e-01 0.641 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.674278e-01 0.776 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.438196e-01 0.842 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 2.653152e-01 0.576 0 0
SOS-mediated signalling R-HSA-112412 2.653152e-01 0.576 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 2.653152e-01 0.576 0 0
PLC-gamma1 signalling R-HSA-167021 3.944010e-01 0.404 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 3.944010e-01 0.404 0 0
Defective ABCD4 causes MAHCJ R-HSA-5683329 3.944010e-01 0.404 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.944010e-01 0.404 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.944010e-01 0.404 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.624066e-01 0.789 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 1.624066e-01 0.789 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.177982e-01 0.662 0 0
Scavenging by Class F Receptors R-HSA-3000484 2.177982e-01 0.662 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.381051e-01 0.860 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.381051e-01 0.860 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.381051e-01 0.860 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.381051e-01 0.860 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.180749e-01 0.928 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.180749e-01 0.928 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 3.021590e-01 0.520 0 0
Formation of annular gap junctions R-HSA-196025 3.021590e-01 0.520 0 0
HIV elongation arrest and recovery R-HSA-167287 1.305011e-01 0.884 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.305011e-01 0.884 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 2.440460e-01 0.613 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 1.116347e-01 0.952 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.223990e-01 0.912 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.336727e-01 0.874 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 2.226498e-01 0.652 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.226498e-01 0.652 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.386657e-01 0.470 0 0
Gap junction degradation R-HSA-190873 3.386657e-01 0.470 0 0
WNT mediated activation of DVL R-HSA-201688 3.386657e-01 0.470 1 1
ALK mutants bind TKIs R-HSA-9700645 3.386657e-01 0.470 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 4.522100e-01 0.345 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 4.522100e-01 0.345 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 4.522100e-01 0.345 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 4.522100e-01 0.345 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 4.522100e-01 0.345 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 2.977619e-01 0.526 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.655812e-01 0.576 0 0
Regulation of the apoptosome activity R-HSA-9627069 3.745640e-01 0.426 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.745640e-01 0.426 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.326443e-01 0.877 0 0
Dual incision in TC-NER R-HSA-6782135 1.326443e-01 0.877 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 3.249045e-01 0.488 0 0
Phosphorylation of the APC/C R-HSA-176412 3.249045e-01 0.488 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 3.249045e-01 0.488 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.970092e-01 0.706 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 1.970092e-01 0.706 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.205079e-01 0.919 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 1.799158e-01 0.745 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 2.875918e-01 0.541 0 0
Telomere Extension By Telomerase R-HSA-171319 2.575478e-01 0.589 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 2.575478e-01 0.589 0 0
Formation of the Early Elongation Complex R-HSA-113418 2.575478e-01 0.589 0 0
Centrosome maturation R-HSA-380287 1.361777e-01 0.866 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 3.098441e-01 0.509 0 0
NrCAM interactions R-HSA-447038 5.045039e-01 0.297 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 5.045039e-01 0.297 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 3.322514e-01 0.479 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 3.322514e-01 0.479 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 3.790453e-01 0.421 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 3.790453e-01 0.421 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 3.790453e-01 0.421 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 3.547316e-01 0.450 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 4.437174e-01 0.353 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.474242e-01 0.607 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 4.057986e-01 0.392 0 0
PKA activation R-HSA-163615 4.057986e-01 0.392 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 4.057986e-01 0.392 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.398295e-01 0.620 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.398295e-01 0.620 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 3.338742e-01 0.476 0 0
Separation of Sister Chromatids R-HSA-2467813 1.582117e-01 0.801 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 3.152212e-01 0.501 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 4.321995e-01 0.364 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 4.766732e-01 0.322 0 0
Polymerase switching R-HSA-69091 4.766732e-01 0.322 0 0
Leading Strand Synthesis R-HSA-69109 4.766732e-01 0.322 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 5.518083e-01 0.258 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 5.518083e-01 0.258 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 5.518083e-01 0.258 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 5.518083e-01 0.258 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 5.518083e-01 0.258 0 0
Loss-of-function mutations in DLD cause MSUD3/DLDD R-HSA-9907570 5.518083e-01 0.258 0 0
Signaling by MAPK mutants R-HSA-9652817 5.518083e-01 0.258 0 0
Loss-of-function mutations in DBT cause MSUD2 R-HSA-9865113 5.518083e-01 0.258 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.723560e-01 0.565 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 3.689827e-01 0.433 0 0
HIV Transcription Initiation R-HSA-167161 3.689827e-01 0.433 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 3.689827e-01 0.433 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 4.218587e-01 0.375 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.218587e-01 0.375 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 3.547506e-01 0.450 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 4.042210e-01 0.393 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 4.835969e-01 0.316 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 4.835969e-01 0.316 0 0
Lagging Strand Synthesis R-HSA-69186 4.835969e-01 0.316 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.126478e-01 0.384 1 1
Meiotic synapsis R-HSA-1221632 4.126478e-01 0.384 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.126478e-01 0.384 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 4.393067e-01 0.357 0 0
Translation initiation complex formation R-HSA-72649 4.287503e-01 0.368 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 5.084492e-01 0.294 0 0
VLDL assembly R-HSA-8866423 5.945992e-01 0.226 0 0
Chylomicron clearance R-HSA-8964026 5.945992e-01 0.226 0 0
STAT5 Activation R-HSA-9645135 5.945992e-01 0.226 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.945992e-01 0.226 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 5.945992e-01 0.226 0 0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD R-HSA-9865125 5.945992e-01 0.226 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 5.945992e-01 0.226 0 0
H139Hfs13* PPM1K causes a mild variant of MSUD R-HSA-9912529 5.945992e-01 0.226 0 0
Defective CHST3 causes SEDCJD R-HSA-3595172 5.945992e-01 0.226 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 5.945992e-01 0.226 0 0
Branched-chain ketoacid dehydrogenase kinase deficiency R-HSA-9912481 5.945992e-01 0.226 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 4.280548e-01 0.369 0 0
FGFR2 alternative splicing R-HSA-6803529 5.326594e-01 0.274 0 0
Processive synthesis on the lagging strand R-HSA-69183 5.679764e-01 0.246 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 5.679764e-01 0.246 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 5.679764e-01 0.246 0 0
Translesion synthesis by REV1 R-HSA-110312 5.679764e-01 0.246 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 4.843873e-01 0.315 0 0
Post-translational protein phosphorylation R-HSA-8957275 5.323268e-01 0.274 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 5.574333e-01 0.254 0 0
Deadenylation of mRNA R-HSA-429947 5.789789e-01 0.237 0 0
Translesion synthesis by POLI R-HSA-5656121 5.957405e-01 0.225 0 0
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782 6.333070e-01 0.198 0 0
VLDL clearance R-HSA-8964046 6.333070e-01 0.198 0 0
Defective CHSY1 causes TPBS R-HSA-3595177 6.333070e-01 0.198 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 5.733858e-01 0.242 0 0
Dual Incision in GG-NER R-HSA-5696400 5.883619e-01 0.230 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 6.044065e-01 0.219 0 0
Translesion synthesis by POLK R-HSA-5655862 6.221437e-01 0.206 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 6.194462e-01 0.208 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 6.295851e-01 0.201 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 6.295851e-01 0.201 0 0
Recycling pathway of L1 R-HSA-437239 6.453803e-01 0.190 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 6.453803e-01 0.190 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 6.427729e-01 0.192 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 6.471927e-01 0.189 0 0
Type I hemidesmosome assembly R-HSA-446107 6.683210e-01 0.175 0 0
ALKBH3 mediated reversal of alkylation damage R-HSA-112126 6.683210e-01 0.175 0 0
phospho-PLA2 pathway R-HSA-111995 6.683210e-01 0.175 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 6.683210e-01 0.175 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 6.683210e-01 0.175 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 6.683210e-01 0.175 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 6.624567e-01 0.179 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 6.624567e-01 0.179 0 0
Transcription of the HIV genome R-HSA-167172 2.373592e-01 0.625 0 0
Signaling by EGFR in Cancer R-HSA-1643713 6.222923e-01 0.206 0 0
Cap-dependent Translation Initiation R-HSA-72737 4.311432e-01 0.365 0 0
Downstream signal transduction R-HSA-186763 5.082688e-01 0.294 0 0
HIV Transcription Elongation R-HSA-167169 1.970092e-01 0.706 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 1.571160e-01 0.804 0 0
Chromosome Maintenance R-HSA-73886 3.806651e-01 0.419 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.437174e-01 0.353 0 0
DNA Damage Bypass R-HSA-73893 3.482059e-01 0.458 0 0
Telomere Maintenance R-HSA-157579 5.201908e-01 0.284 0 0
mRNA Capping R-HSA-72086 4.656897e-01 0.332 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 3.996051e-01 0.398 0 0
Eukaryotic Translation Initiation R-HSA-72613 4.311432e-01 0.365 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 1.818047e-01 0.740 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 1.694375e-01 0.771 0 0
Formation of apoptosome R-HSA-111458 3.745640e-01 0.426 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.096378e-01 0.388 0 0
Extension of Telomeres R-HSA-180786 2.348125e-01 0.629 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 5.265091e-01 0.279 0 0
Cellular response to starvation R-HSA-9711097 5.943912e-01 0.226 0 0
Activation of the pre-replicative complex R-HSA-68962 2.954884e-01 0.529 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 4.835969e-01 0.316 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.739818e-01 0.324 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 3.675745e-01 0.435 0 0
HSF1-dependent transactivation R-HSA-3371571 1.439499e-01 0.842 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 1.970092e-01 0.706 0 0
Fanconi Anemia Pathway R-HSA-6783310 4.393067e-01 0.357 0 0
Integration of provirus R-HSA-162592 1.921949e-01 0.716 0 0
Receptor Mediated Mitophagy R-HSA-8934903 3.745640e-01 0.426 1 1
EPH-Ephrin signaling R-HSA-2682334 1.521728e-01 0.818 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.550129e-01 0.810 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 4.393067e-01 0.357 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 5.223228e-01 0.282 0 0
DCC mediated attractive signaling R-HSA-418885 1.261366e-01 0.899 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.261366e-01 0.899 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 2.707570e-01 0.567 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 4.923645e-01 0.308 0 0
PCP/CE pathway R-HSA-4086400 4.942575e-01 0.306 0 0
COPI-mediated anterograde transport R-HSA-6807878 5.079611e-01 0.294 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 5.445914e-01 0.264 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 5.386206e-01 0.269 0 0
Insulin receptor recycling R-HSA-77387 6.624567e-01 0.179 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 6.650673e-01 0.177 0 0
Generation of second messenger molecules R-HSA-202433 5.081179e-01 0.294 0 0
PERK regulates gene expression R-HSA-381042 2.486929e-01 0.604 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.885763e-01 0.411 0 0
UCH proteinases R-HSA-5689603 4.666467e-01 0.331 0 0
Regulation of CDH1 Function R-HSA-9764561 3.298757e-01 0.482 0 0
Meiosis R-HSA-1500620 3.331933e-01 0.477 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 2.653152e-01 0.576 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 3.021590e-01 0.520 0 0
Regulation of CDH11 function R-HSA-9762292 3.745640e-01 0.426 0 0
PI3K/AKT activation R-HSA-198203 3.745640e-01 0.426 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 1.834868e-01 0.736 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.970092e-01 0.706 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.109088e-01 0.676 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.960893e-01 0.708 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 5.326594e-01 0.274 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.957405e-01 0.225 0 0
Integrin signaling R-HSA-354192 5.492488e-01 0.260 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.019181e-01 0.695 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 5.974120e-01 0.224 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 5.883619e-01 0.230 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.686335e-01 0.773 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.591836e-01 0.798 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.032317e-01 0.692 0 0
EPHB-mediated forward signaling R-HSA-3928662 4.217997e-01 0.375 0 0
Post NMDA receptor activation events R-HSA-438064 3.703922e-01 0.431 0 0
IGF1R signaling cascade R-HSA-2428924 5.830687e-01 0.234 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 4.522100e-01 0.345 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.541914e-01 0.812 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 5.045039e-01 0.297 0 0
NF-kB is activated and signals survival R-HSA-209560 4.437174e-01 0.353 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 4.766732e-01 0.322 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 4.766732e-01 0.322 0 0
Signaling by MST1 R-HSA-8852405 5.518083e-01 0.258 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 3.331933e-01 0.477 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 6.683210e-01 0.175 0 0
Ca-dependent events R-HSA-111996 2.397286e-01 0.620 0 0
Signaling by VEGF R-HSA-194138 2.468829e-01 0.608 0 0
Myogenesis R-HSA-525793 3.996051e-01 0.398 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 4.766732e-01 0.322 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.766732e-01 0.322 0 0
RNA Polymerase I Transcription R-HSA-73864 3.631960e-01 0.440 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.447970e-01 0.352 0 0
Degradation of DVL R-HSA-4641258 6.431217e-01 0.192 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 6.427729e-01 0.192 0 0
CaM pathway R-HSA-111997 2.652725e-01 0.576 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 1.834868e-01 0.736 0 0
Degradation of CDH1 R-HSA-9766229 5.080161e-01 0.294 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 6.222923e-01 0.206 0 0
Calmodulin induced events R-HSA-111933 2.652725e-01 0.576 0 0
DAG and IP3 signaling R-HSA-1489509 1.680026e-01 0.775 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 1.624066e-01 0.789 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 2.440460e-01 0.613 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.019181e-01 0.695 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 3.386657e-01 0.470 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.576774e-01 0.802 0 0
MAP2K and MAPK activation R-HSA-5674135 2.251581e-01 0.648 0 0
Formation of the posterior neural plate R-HSA-9832991 4.096378e-01 0.388 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 5.045039e-01 0.297 0 0
Activation of AKT2 R-HSA-165158 5.045039e-01 0.297 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 3.790453e-01 0.421 0 0
Signaling by FGFR4 in disease R-HSA-5655291 5.388581e-01 0.269 0 0
Aggrephagy R-HSA-9646399 5.081179e-01 0.294 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 4.727648e-01 0.325 0 0
Synthesis of DNA R-HSA-69239 5.313170e-01 0.275 0 0
Killing mechanisms R-HSA-9664420 5.957405e-01 0.225 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 5.957405e-01 0.225 0 0
LDL remodeling R-HSA-8964041 6.333070e-01 0.198 0 0
PTK6 Expression R-HSA-8849473 6.333070e-01 0.198 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 6.010228e-01 0.221 0 0
Tight junction interactions R-HSA-420029 6.010228e-01 0.221 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 6.572254e-01 0.182 0 0
PLC beta mediated events R-HSA-112043 3.893627e-01 0.410 0 0
MTOR signalling R-HSA-165159 1.345758e-01 0.871 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 2.486929e-01 0.604 0 0
Mismatch Repair R-HSA-5358508 2.019181e-01 0.695 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 5.079611e-01 0.294 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 2.498552e-01 0.602 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.873271e-01 0.231 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 3.547506e-01 0.450 0 0
G-protein mediated events R-HSA-112040 3.408873e-01 0.467 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.242550e-01 0.906 0 0
mTORC1-mediated signalling R-HSA-166208 1.534367e-01 0.814 0 0
Acyl chain remodelling of PS R-HSA-1482801 2.032317e-01 0.692 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.047747e-01 0.689 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 3.996051e-01 0.398 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.271134e-01 0.485 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.920298e-01 0.717 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.921949e-01 0.716 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 3.021590e-01 0.520 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 5.045039e-01 0.297 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 5.045039e-01 0.297 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 3.370513e-01 0.472 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 3.706633e-01 0.431 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 4.107198e-01 0.386 0 0
Diseases of mitotic cell cycle R-HSA-9675126 5.289772e-01 0.277 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 6.471927e-01 0.189 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 6.683210e-01 0.175 0 0
Mitotic Anaphase R-HSA-68882 1.581764e-01 0.801 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 4.605573e-01 0.337 0 0
RAF activation R-HSA-5673000 2.324232e-01 0.634 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 3.996051e-01 0.398 0 0
Chaperonin-mediated protein folding R-HSA-390466 4.949987e-01 0.305 1 0
Prolonged ERK activation events R-HSA-169893 5.957405e-01 0.225 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.634114e-01 0.787 0 0
Signal attenuation R-HSA-74749 1.436973e-01 0.843 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.439028e-01 0.613 0 0
HSF1 activation R-HSA-3371511 4.320673e-01 0.364 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 4.835969e-01 0.316 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 5.081179e-01 0.294 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 5.081179e-01 0.294 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 5.265091e-01 0.279 0 0
TCF dependent signaling in response to WNT R-HSA-201681 6.413136e-01 0.193 1 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.845678e-01 0.546 0 0
Heme signaling R-HSA-9707616 2.732968e-01 0.563 0 0
Cilium Assembly R-HSA-5617833 6.135740e-01 0.212 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 2.954884e-01 0.529 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.732968e-01 0.563 0 0
Vesicle-mediated transport R-HSA-5653656 5.221271e-01 0.282 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 6.453803e-01 0.190 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 2.177982e-01 0.662 0 0
p75NTR signals via NF-kB R-HSA-193639 5.679764e-01 0.246 0 0
Semaphorin interactions R-HSA-373755 2.865206e-01 0.543 0 0
Apoptotic factor-mediated response R-HSA-111471 4.057986e-01 0.392 0 0
Signaling by FGFR in disease R-HSA-1226099 3.112679e-01 0.507 0 0
Axon guidance R-HSA-422475 5.598176e-01 0.252 1 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.005612e-01 0.397 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 5.684800e-01 0.245 0 0
Cellular Senescence R-HSA-2559583 1.530554e-01 0.815 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.954884e-01 0.529 0 0
Nervous system development R-HSA-9675108 5.429805e-01 0.265 1 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.598509e-01 0.585 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 1.212088e-01 0.916 0 0
Neurophilin interactions with VEGF and VEGFR R-HSA-194306 3.304955e-01 0.481 0 0
Regulation of cortical dendrite branching R-HSA-8985801 3.304955e-01 0.481 0 0
Bicarbonate transporters R-HSA-425381 1.674278e-01 0.776 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 3.944010e-01 0.404 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 1.860543e-01 0.730 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 4.522100e-01 0.345 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.032317e-01 0.692 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.154063e-01 0.938 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 2.209123e-01 0.656 0 0
Metalloprotease DUBs R-HSA-5689901 2.209123e-01 0.656 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 2.655812e-01 0.576 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 3.249045e-01 0.488 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 2.575478e-01 0.589 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 5.045039e-01 0.297 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 3.547316e-01 0.450 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.437174e-01 0.353 0 0
Sodium/Calcium exchangers R-HSA-425561 4.437174e-01 0.353 0 0
ERKs are inactivated R-HSA-202670 4.437174e-01 0.353 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.850716e-01 0.545 0 0
Viral Messenger RNA Synthesis R-HSA-168325 2.602584e-01 0.585 0 0
PKB-mediated events R-HSA-109703 5.518083e-01 0.258 0 0
Cam-PDE 1 activation R-HSA-111957 5.518083e-01 0.258 0 0
PDE3B signalling R-HSA-165160 5.518083e-01 0.258 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 5.518083e-01 0.258 0 0
Mitotic Prophase R-HSA-68875 3.700949e-01 0.432 0 0
Switching of origins to a post-replicative state R-HSA-69052 4.247491e-01 0.372 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 5.388581e-01 0.269 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.679764e-01 0.246 0 0
Orc1 removal from chromatin R-HSA-68949 5.574333e-01 0.254 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 6.333070e-01 0.198 0 0
Disinhibition of SNARE formation R-HSA-114516 6.333070e-01 0.198 0 0
GPER1 signaling R-HSA-9634597 6.607456e-01 0.180 0 0
Response of endothelial cells to shear stress R-HSA-9860931 6.026711e-01 0.220 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 3.513937e-01 0.454 0 0
Early Phase of HIV Life Cycle R-HSA-162594 1.234921e-01 0.908 0 0
FGFR1 mutant receptor activation R-HSA-1839124 2.009756e-01 0.697 0 0
Neurexins and neuroligins R-HSA-6794361 2.581812e-01 0.588 0 0
Somitogenesis R-HSA-9824272 6.133701e-01 0.212 0 0
Selective autophagy R-HSA-9663891 6.363930e-01 0.196 1 0
Biotin transport and metabolism R-HSA-196780 2.977619e-01 0.526 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.547316e-01 0.450 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 6.559050e-01 0.183 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 1.261366e-01 0.899 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 5.475480e-01 0.262 0 0
Uptake and function of anthrax toxins R-HSA-5210891 1.818047e-01 0.740 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 3.790453e-01 0.421 0 0
Netrin-1 signaling R-HSA-373752 2.697154e-01 0.569 0 0
DNA Damage Reversal R-HSA-73942 2.977619e-01 0.526 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 2.284690e-01 0.641 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 1.674278e-01 0.776 0 0
tRNA processing in the nucleus R-HSA-6784531 2.732968e-01 0.563 0 0
NRIF signals cell death from the nucleus R-HSA-205043 5.388581e-01 0.269 0 0
Protein-protein interactions at synapses R-HSA-6794362 1.486868e-01 0.828 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.407300e-01 0.852 0 0
DARPP-32 events R-HSA-180024 4.656897e-01 0.332 0 0
Ion homeostasis R-HSA-5578775 6.194462e-01 0.208 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 6.453803e-01 0.190 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 5.365683e-01 0.270 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.116347e-01 0.952 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.019181e-01 0.695 0 0
Interleukin-1 processing R-HSA-448706 3.386657e-01 0.470 0 0
Muscarinic acetylcholine receptors R-HSA-390648 5.045039e-01 0.297 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 5.797495e-01 0.237 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 6.683210e-01 0.175 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.656897e-01 0.332 0 0
Protein folding R-HSA-391251 5.709439e-01 0.243 1 0
Listeria monocytogenes entry into host cells R-HSA-8876384 5.084492e-01 0.294 0 0
FLT3 signaling in disease R-HSA-9682385 6.254127e-01 0.204 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 3.386657e-01 0.470 0 0
TGFBR3 expression R-HSA-9839394 2.032317e-01 0.692 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 5.045039e-01 0.297 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 5.084492e-01 0.294 0 0
Signaling by ROBO receptors R-HSA-376176 4.662046e-01 0.331 0 0
Cellular responses to stress R-HSA-2262752 5.628452e-01 0.250 1 0
Intrinsic Pathway for Apoptosis R-HSA-109606 6.194462e-01 0.208 0 0
RMTs methylate histone arginines R-HSA-3214858 4.217997e-01 0.375 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 5.082688e-01 0.294 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 5.492488e-01 0.260 0 0
G2/M Transition R-HSA-69275 4.908286e-01 0.309 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 6.222923e-01 0.206 0 0
Cellular responses to stimuli R-HSA-8953897 6.247783e-01 0.204 1 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.436973e-01 0.843 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 1.534367e-01 0.814 0 0
Ovarian tumor domain proteases R-HSA-5689896 6.431217e-01 0.192 0 0
Mitotic G2-G2/M phases R-HSA-453274 5.085723e-01 0.294 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 4.656897e-01 0.332 0 0
Elastic fibre formation R-HSA-1566948 4.705236e-01 0.327 0 0
Host Interactions of HIV factors R-HSA-162909 4.125661e-01 0.385 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.377036e-01 0.624 0 0
Signaling by ERBB4 R-HSA-1236394 3.112679e-01 0.507 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 2.284690e-01 0.641 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 3.944010e-01 0.404 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 2.440460e-01 0.613 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 1.858765e-01 0.731 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 2.009756e-01 0.697 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 3.745640e-01 0.426 0 0
Transport of RCbl within the body R-HSA-9758890 4.096378e-01 0.388 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 5.045039e-01 0.297 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.437174e-01 0.353 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 5.518083e-01 0.258 0 0
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399 5.518083e-01 0.258 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 4.439057e-01 0.353 0 0
RET signaling R-HSA-8853659 4.320673e-01 0.364 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 5.561816e-01 0.255 0 0
Ca2+ activated K+ channels R-HSA-1296052 6.333070e-01 0.198 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 5.634120e-01 0.249 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 6.683210e-01 0.175 0 0
TGFBR3 PTM regulation R-HSA-9839383 6.683210e-01 0.175 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 6.683210e-01 0.175 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.951019e-01 0.530 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 4.218587e-01 0.375 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 4.028123e-01 0.395 0 0
RNA Polymerase II Transcription R-HSA-73857 1.566618e-01 0.805 1 0
Formation of definitive endoderm R-HSA-9823730 4.581582e-01 0.339 0 0
Gastrulation R-HSA-9758941 4.116729e-01 0.385 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 5.265091e-01 0.279 0 0
Signaling by ERBB2 R-HSA-1227986 5.233803e-01 0.281 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 1.920298e-01 0.717 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 2.440460e-01 0.613 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 6.071546e-01 0.217 0 0
Signaling by Nuclear Receptors R-HSA-9006931 6.135340e-01 0.212 0 0
Other interleukin signaling R-HSA-449836 4.321995e-01 0.364 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 6.248791e-01 0.204 1 1
Signaling by TGFB family members R-HSA-9006936 1.897065e-01 0.722 0 0
Apoptosis R-HSA-109581 2.033400e-01 0.692 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.875918e-01 0.541 0 0
PECAM1 interactions R-HSA-210990 4.096378e-01 0.388 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.954884e-01 0.529 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 3.538349e-01 0.451 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 5.326594e-01 0.274 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 4.933947e-01 0.307 0 0
Kinesins R-HSA-983189 5.233803e-01 0.281 0 0
RUNX2 regulates bone development R-HSA-8941326 4.320673e-01 0.364 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.694375e-01 0.771 0 0
Signaling by TGFBR3 R-HSA-9839373 3.006291e-01 0.522 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 5.690525e-01 0.245 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 1.541914e-01 0.812 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 5.492488e-01 0.260 0 0
Inositol phosphate metabolism R-HSA-1483249 3.649902e-01 0.438 0 0
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis R-HSA-9708296 3.304955e-01 0.481 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 2.653152e-01 0.576 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.381051e-01 0.860 0 0
Sodium/Proton exchangers R-HSA-425986 3.021590e-01 0.520 0 0
Dopamine receptors R-HSA-390651 4.522100e-01 0.345 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 3.745640e-01 0.426 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 3.745640e-01 0.426 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 2.109088e-01 0.676 0 0
Metal ion SLC transporters R-HSA-425410 2.047931e-01 0.689 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 5.045039e-01 0.297 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 5.045039e-01 0.297 0 0
VEGF ligand-receptor interactions R-HSA-194313 5.518083e-01 0.258 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 5.518083e-01 0.258 0 0
Trafficking of AMPA receptors R-HSA-399719 5.082688e-01 0.294 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.679764e-01 0.246 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.957405e-01 0.225 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 6.333070e-01 0.198 0 0
Netrin mediated repulsion signals R-HSA-418886 6.333070e-01 0.198 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 6.333070e-01 0.198 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 6.683210e-01 0.175 0 0
Zinc transporters R-HSA-435354 2.707570e-01 0.567 0 0
Interleukin-7 signaling R-HSA-1266695 2.032317e-01 0.692 0 0
Sensory processing of sound R-HSA-9659379 6.435577e-01 0.191 0 0
G1/S Transition R-HSA-69206 6.464239e-01 0.189 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 5.797316e-01 0.237 0 0
Programmed Cell Death R-HSA-5357801 3.305056e-01 0.481 0 0
Potential therapeutics for SARS R-HSA-9679191 4.213674e-01 0.375 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.386657e-01 0.470 0 0
Toxicity of botulinum toxin type C (botC) R-HSA-5250971 1.564929e-01 0.806 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 1.920298e-01 0.717 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 2.653152e-01 0.576 0 0
Expression and Processing of Neurotrophins R-HSA-9036866 3.944010e-01 0.404 0 0
NGF processing R-HSA-167060 3.944010e-01 0.404 0 0
Signal regulatory protein family interactions R-HSA-391160 2.707570e-01 0.567 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.386657e-01 0.470 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.977619e-01 0.526 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.977619e-01 0.526 0 0
LGI-ADAM interactions R-HSA-5682910 4.096378e-01 0.388 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 5.045039e-01 0.297 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.006291e-01 0.522 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 5.518083e-01 0.258 0 0
HDL clearance R-HSA-8964011 5.945992e-01 0.226 0 0
Formation of the anterior neural plate R-HSA-9823739 5.679764e-01 0.246 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 5.542722e-01 0.256 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 6.650673e-01 0.177 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 1.180749e-01 0.928 0 0
Death Receptor Signaling R-HSA-73887 1.517566e-01 0.819 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 2.019181e-01 0.695 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 5.326594e-01 0.274 0 0
Gene Silencing by RNA R-HSA-211000 6.466520e-01 0.189 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.627524e-01 0.788 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 3.675745e-01 0.435 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.438196e-01 0.842 0 0
Cellular response to mitochondrial stress R-HSA-9840373 3.386657e-01 0.470 0 0
Josephin domain DUBs R-HSA-5689877 3.745640e-01 0.426 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 6.341559e-01 0.198 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 6.683210e-01 0.175 0 0
Signaling by EGFR R-HSA-177929 6.194462e-01 0.208 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 5.945992e-01 0.226 0 0
Neurofascin interactions R-HSA-447043 5.945992e-01 0.226 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 6.683210e-01 0.175 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 6.683210e-01 0.175 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 6.602708e-01 0.180 0 0
Regulation of TP53 Degradation R-HSA-6804757 6.254127e-01 0.204 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 5.445914e-01 0.264 0 0
XBP1(S) activates chaperone genes R-HSA-381038 2.505068e-01 0.601 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 6.333070e-01 0.198 0 0
Insulin processing R-HSA-264876 6.427729e-01 0.192 0 0
IRE1alpha activates chaperones R-HSA-381070 3.177254e-01 0.498 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 5.492488e-01 0.260 0 0
Signaling by Leptin R-HSA-2586552 3.745640e-01 0.426 0 0
STING mediated induction of host immune responses R-HSA-1834941 4.321995e-01 0.364 0 0
Specification of primordial germ cells R-HSA-9827857 6.471927e-01 0.189 0 0
Synthesis and processing of ENV and VPU R-HSA-171286 3.304955e-01 0.481 0 0
Interleukin-37 signaling R-HSA-9008059 4.871593e-01 0.312 0 0
G alpha (12/13) signalling events R-HSA-416482 4.942575e-01 0.306 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 6.699714e-01 0.174 0 0
Platelet sensitization by LDL R-HSA-432142 6.709054e-01 0.173 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 6.709054e-01 0.173 0 0
PKA activation in glucagon signalling R-HSA-164378 6.709054e-01 0.173 0 0
GAB1 signalosome R-HSA-180292 6.709054e-01 0.173 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 6.709054e-01 0.173 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 6.762111e-01 0.170 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 6.768525e-01 0.170 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 6.768525e-01 0.170 0 0
TCR signaling R-HSA-202403 6.778329e-01 0.169 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 6.812294e-01 0.167 0 0
Termination of translesion DNA synthesis R-HSA-5656169 6.813407e-01 0.167 0 0
Platelet calcium homeostasis R-HSA-418360 6.813407e-01 0.167 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 6.813407e-01 0.167 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.900812e-01 0.161 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 6.900812e-01 0.161 0 0
PI3K Cascade R-HSA-109704 6.901575e-01 0.161 0 0
Attenuation phase R-HSA-3371568 6.928623e-01 0.159 0 0
Diseases of Immune System R-HSA-5260271 6.928623e-01 0.159 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 6.928623e-01 0.159 0 0
Translesion Synthesis by POLH R-HSA-110320 6.933085e-01 0.159 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.933085e-01 0.159 0 0
The NLRP3 inflammasome R-HSA-844456 6.933085e-01 0.159 0 0
Generic Transcription Pathway R-HSA-212436 6.972168e-01 0.157 1 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 6.994268e-01 0.155 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 6.994268e-01 0.155 0 0
Activation of BH3-only proteins R-HSA-114452 6.994268e-01 0.155 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 6.994268e-01 0.155 0 0
ARMS-mediated activation R-HSA-170984 6.999935e-01 0.155 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 6.999935e-01 0.155 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 6.999935e-01 0.155 0 0
Lipophagy R-HSA-9613354 6.999935e-01 0.155 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 6.999935e-01 0.155 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 6.999935e-01 0.155 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 6.999935e-01 0.155 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 6.999935e-01 0.155 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 6.999935e-01 0.155 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 6.999935e-01 0.155 0 0
GP1b-IX-V activation signalling R-HSA-430116 6.999935e-01 0.155 0 0
Regulated proteolysis of p75NTR R-HSA-193692 6.999935e-01 0.155 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 6.999935e-01 0.155 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 6.999935e-01 0.155 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 6.999935e-01 0.155 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 7.001966e-01 0.155 0 0
Signaling by PDGF R-HSA-186797 7.024523e-01 0.153 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 7.024523e-01 0.153 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 7.024523e-01 0.153 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.027028e-01 0.153 0 0
Reproduction R-HSA-1474165 7.027960e-01 0.153 0 0
Assembly of the pre-replicative complex R-HSA-68867 7.038793e-01 0.153 0 0
Meiotic recombination R-HSA-912446 7.041944e-01 0.152 0 0
Macroautophagy R-HSA-1632852 7.139601e-01 0.146 1 0
VxPx cargo-targeting to cilium R-HSA-5620916 7.144358e-01 0.146 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 7.144358e-01 0.146 0 0
Co-inhibition by CTLA4 R-HSA-389513 7.144358e-01 0.146 0 0
Signal transduction by L1 R-HSA-445144 7.144358e-01 0.146 1 1
Common Pathway of Fibrin Clot Formation R-HSA-140875 7.144358e-01 0.146 0 0
Opioid Signalling R-HSA-111885 7.153750e-01 0.145 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.167213e-01 0.145 0 0
Budding and maturation of HIV virion R-HSA-162588 7.167213e-01 0.145 0 0
Molecules associated with elastic fibres R-HSA-2129379 7.167213e-01 0.145 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 7.167907e-01 0.145 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 7.177818e-01 0.144 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 7.231611e-01 0.141 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 7.244006e-01 0.140 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.244902e-01 0.140 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 7.260441e-01 0.139 0 0
Insulin receptor signalling cascade R-HSA-74751 7.272194e-01 0.138 0 0
Organelle biogenesis and maintenance R-HSA-1852241 7.277193e-01 0.138 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 7.286432e-01 0.137 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 7.286432e-01 0.137 0 0
Folding of actin by CCT/TriC R-HSA-390450 7.286432e-01 0.137 0 0
Binding and entry of HIV virion R-HSA-173107 7.286432e-01 0.137 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 7.286432e-01 0.137 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 7.286432e-01 0.137 0 0
Pexophagy R-HSA-9664873 7.286432e-01 0.137 0 0
CASP4 inflammasome assembly R-HSA-9948001 7.286432e-01 0.137 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 7.305010e-01 0.136 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 7.309192e-01 0.136 0 0
Amino acids regulate mTORC1 R-HSA-9639288 7.309192e-01 0.136 0 0
Smooth Muscle Contraction R-HSA-445355 7.309192e-01 0.136 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 7.343268e-01 0.134 0 0
Basigin interactions R-HSA-210991 7.343268e-01 0.134 0 0
ERK/MAPK targets R-HSA-198753 7.343268e-01 0.134 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 7.343268e-01 0.134 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 7.344418e-01 0.134 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 7.390463e-01 0.131 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 7.436075e-01 0.129 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 7.476737e-01 0.126 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 7.511813e-01 0.124 0 0
L1CAM interactions R-HSA-373760 7.526100e-01 0.123 1 0
Serine metabolism R-HSA-977347 7.530247e-01 0.123 0 0
Chylomicron assembly R-HSA-8963888 7.545586e-01 0.122 0 0
Signaling by APC mutants R-HSA-4839744 7.545586e-01 0.122 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 7.545586e-01 0.122 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 7.545586e-01 0.122 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 7.545586e-01 0.122 0 0
Ionotropic activity of kainate receptors R-HSA-451306 7.545586e-01 0.122 0 0
vRNP Assembly R-HSA-192905 7.545586e-01 0.122 0 0
Synthesis of PI R-HSA-1483226 7.545586e-01 0.122 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 7.545586e-01 0.122 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 7.545586e-01 0.122 0 0
Suppression of apoptosis R-HSA-9635465 7.545586e-01 0.122 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.545586e-01 0.122 0 0
Dissolution of Fibrin Clot R-HSA-75205 7.545586e-01 0.122 0 0
Autophagy R-HSA-9612973 7.551384e-01 0.122 1 0
Rab regulation of trafficking R-HSA-9007101 7.610642e-01 0.119 0 0
Mitochondrial biogenesis R-HSA-1592230 7.610642e-01 0.119 0 0
Miscellaneous transport and binding events R-HSA-5223345 7.639667e-01 0.117 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 7.677845e-01 0.115 0 0
DNA Replication Pre-Initiation R-HSA-69002 7.702277e-01 0.113 0 0
Neurotransmitter release cycle R-HSA-112310 7.741366e-01 0.111 0 0
Signaling by NTRKs R-HSA-166520 7.763644e-01 0.110 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 7.769694e-01 0.110 0 0
Nucleosome assembly R-HSA-774815 7.769694e-01 0.110 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 7.769694e-01 0.110 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 7.769694e-01 0.110 0 0
DS-GAG biosynthesis R-HSA-2022923 7.780003e-01 0.109 0 0
Scavenging by Class H Receptors R-HSA-3000497 7.780003e-01 0.109 0 0
Activation of RAC1 R-HSA-428540 7.780003e-01 0.109 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 7.780003e-01 0.109 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 7.780003e-01 0.109 0 0
Signaling by GSK3beta mutants R-HSA-5339716 7.780003e-01 0.109 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 7.780003e-01 0.109 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 7.780003e-01 0.109 0 0
Signaling by AXIN mutants R-HSA-4839735 7.780003e-01 0.109 0 0
Signaling by AMER1 mutants R-HSA-4839748 7.780003e-01 0.109 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 7.780003e-01 0.109 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 7.780003e-01 0.109 0 0
Uptake of dietary cobalamins into enterocytes R-HSA-9758881 7.780003e-01 0.109 0 0
Signaling by NOTCH2 R-HSA-1980145 7.782204e-01 0.109 0 0
Mitophagy R-HSA-5205647 7.782204e-01 0.109 1 0
NOD1/2 Signaling Pathway R-HSA-168638 7.782204e-01 0.109 0 0
Signal amplification R-HSA-392518 7.782204e-01 0.109 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 7.782204e-01 0.109 0 0
IRS-mediated signalling R-HSA-112399 7.790072e-01 0.108 0 0
Signaling by WNT R-HSA-195721 7.808106e-01 0.107 1 0
Interleukin receptor SHC signaling R-HSA-912526 7.870292e-01 0.104 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 7.870292e-01 0.104 0 0
Carnitine shuttle R-HSA-200425 7.870292e-01 0.104 0 0
Syndecan interactions R-HSA-3000170 7.870292e-01 0.104 0 0
Growth hormone receptor signaling R-HSA-982772 7.870292e-01 0.104 0 0
Interleukin-1 signaling R-HSA-9020702 7.889608e-01 0.103 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 7.890481e-01 0.103 0 0
Signalling to ERKs R-HSA-187687 7.917577e-01 0.101 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 7.926539e-01 0.101 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 7.926539e-01 0.101 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 7.963669e-01 0.099 0 0
PI Metabolism R-HSA-1483255 7.971933e-01 0.098 0 0
Adipogenesis R-HSA-9843745 7.988339e-01 0.098 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 7.992044e-01 0.097 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 7.992044e-01 0.097 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 7.992044e-01 0.097 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 7.992044e-01 0.097 0 0
Maple Syrup Urine Disease R-HSA-9865114 7.992044e-01 0.097 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 7.992044e-01 0.097 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 7.992044e-01 0.097 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 7.992044e-01 0.097 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 7.992044e-01 0.097 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 7.992044e-01 0.097 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 7.992044e-01 0.097 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 7.992044e-01 0.097 0 0
p75NTR recruits signalling complexes R-HSA-209543 7.992044e-01 0.097 0 0
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854 7.992044e-01 0.097 0 0
Signaling by LTK R-HSA-9842663 7.992044e-01 0.097 0 0
Regulation of IFNG signaling R-HSA-877312 7.992044e-01 0.097 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 7.992044e-01 0.097 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 7.992044e-01 0.097 0 0
MET activates RAS signaling R-HSA-8851805 7.992044e-01 0.097 0 0
OAS antiviral response R-HSA-8983711 7.992044e-01 0.097 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 7.992044e-01 0.097 0 0
Interleukin-15 signaling R-HSA-8983432 7.992044e-01 0.097 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 8.004352e-01 0.097 0 0
Amino acid transport across the plasma membrane R-HSA-352230 8.004352e-01 0.097 0 0
Signaling by Insulin receptor R-HSA-74752 8.006286e-01 0.097 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 8.022909e-01 0.096 0 0
Regulation of mitotic cell cycle R-HSA-453276 8.022909e-01 0.096 0 0
Hedgehog 'on' state R-HSA-5632684 8.022909e-01 0.096 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 8.024338e-01 0.096 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 8.024338e-01 0.096 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 8.045995e-01 0.094 0 0
Signaling by NOTCH R-HSA-157118 8.155281e-01 0.089 0 0
Degradation of AXIN R-HSA-4641257 8.167680e-01 0.088 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 8.168399e-01 0.088 0 0
Defects in cobalamin (B12) metabolism R-HSA-3296469 8.168399e-01 0.088 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 8.168399e-01 0.088 0 0
Chylomicron remodeling R-HSA-8963901 8.183843e-01 0.087 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 8.183843e-01 0.087 0 0
Formation of axial mesoderm R-HSA-9796292 8.183843e-01 0.087 0 0
Frs2-mediated activation R-HSA-170968 8.183843e-01 0.087 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 8.183843e-01 0.087 0 0
rRNA modification in the mitochondrion R-HSA-6793080 8.183843e-01 0.087 0 0
Maturation of nucleoprotein R-HSA-9683610 8.183843e-01 0.087 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 8.183843e-01 0.087 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 8.183843e-01 0.087 0 0
Formation of paraxial mesoderm R-HSA-9793380 8.201889e-01 0.086 0 0
Gap junction trafficking and regulation R-HSA-157858 8.221566e-01 0.085 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 8.242362e-01 0.084 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 8.277420e-01 0.082 0 0
Signaling by NOTCH4 R-HSA-9013694 8.291183e-01 0.081 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 8.294587e-01 0.081 0 0
MET activates PTK2 signaling R-HSA-8874081 8.302978e-01 0.081 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 8.302978e-01 0.081 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 8.302978e-01 0.081 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.321929e-01 0.080 0 0
Removal of the Flap Intermediate R-HSA-69166 8.357332e-01 0.078 0 0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV R-HSA-9859138 8.357332e-01 0.078 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 8.357332e-01 0.078 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 8.357332e-01 0.078 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 8.357332e-01 0.078 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 8.357332e-01 0.078 0 0
Regulation of KIT signaling R-HSA-1433559 8.357332e-01 0.078 0 0
Hydrolysis of LPC R-HSA-1483115 8.357332e-01 0.078 0 0
cGMP effects R-HSA-418457 8.357332e-01 0.078 0 0
CRMPs in Sema3A signaling R-HSA-399956 8.357332e-01 0.078 0 0
Non-canonical inflammasome activation R-HSA-9686114 8.357332e-01 0.078 0 0
Acyl chain remodeling of CL R-HSA-1482798 8.357332e-01 0.078 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 8.357332e-01 0.078 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 8.373867e-01 0.077 0 0
Influenza Infection R-HSA-168255 8.376165e-01 0.077 0 0
Stabilization of p53 R-HSA-69541 8.391780e-01 0.076 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 8.391780e-01 0.076 1 0
Hedgehog ligand biogenesis R-HSA-5358346 8.417525e-01 0.075 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 8.428570e-01 0.074 0 0
Signaling by FGFR3 in disease R-HSA-5655332 8.428570e-01 0.074 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 8.428570e-01 0.074 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 8.428570e-01 0.074 0 0
Interleukin-12 signaling R-HSA-9020591 8.453294e-01 0.073 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 8.468302e-01 0.072 0 0
Ion transport by P-type ATPases R-HSA-936837 8.468302e-01 0.072 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 8.470378e-01 0.072 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 8.494673e-01 0.071 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 8.494673e-01 0.071 0 0
Ribosome-associated quality control R-HSA-9948299 8.500585e-01 0.071 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.508498e-01 0.070 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 8.508498e-01 0.070 0 0
Erythropoietin activates RAS R-HSA-9027284 8.514258e-01 0.070 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 8.514258e-01 0.070 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 8.514258e-01 0.070 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 8.514258e-01 0.070 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 8.514258e-01 0.070 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 8.514258e-01 0.070 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 8.514258e-01 0.070 0 0
Telomere C-strand synthesis initiation R-HSA-174430 8.514258e-01 0.070 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 8.514258e-01 0.070 0 0
p38MAPK events R-HSA-171007 8.514258e-01 0.070 0 0
Protein lipoylation R-HSA-9857492 8.514258e-01 0.070 0 0
Other semaphorin interactions R-HSA-416700 8.514258e-01 0.070 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 8.514258e-01 0.070 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 8.514258e-01 0.070 0 0
Protein methylation R-HSA-8876725 8.514258e-01 0.070 0 0
Spry regulation of FGF signaling R-HSA-1295596 8.514258e-01 0.070 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 8.532332e-01 0.069 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 8.532332e-01 0.069 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 8.532332e-01 0.069 0 0
MAPK family signaling cascades R-HSA-5683057 8.544750e-01 0.068 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 8.545665e-01 0.068 0 0
Inflammasomes R-HSA-622312 8.545665e-01 0.068 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 8.586960e-01 0.066 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 8.591783e-01 0.066 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 8.591783e-01 0.066 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 8.595981e-01 0.066 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 8.607848e-01 0.065 0 0
MyD88-independent TLR4 cascade R-HSA-166166 8.607848e-01 0.065 0 0
SARS-CoV-2-host interactions R-HSA-9705683 8.629902e-01 0.064 0 0
Signal Transduction R-HSA-162582 8.642503e-01 0.063 1 0
Signaling by Erythropoietin R-HSA-9006335 8.654739e-01 0.063 0 0
Late endosomal microautophagy R-HSA-9615710 8.654739e-01 0.063 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 8.654739e-01 0.063 0 0
Regulation of gene expression in beta cells R-HSA-210745 8.654739e-01 0.063 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 8.654739e-01 0.063 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 8.654739e-01 0.063 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 8.656201e-01 0.063 0 0
Activation of SMO R-HSA-5635838 8.656201e-01 0.063 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 8.656201e-01 0.063 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 8.656201e-01 0.063 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 8.656201e-01 0.063 0 0
HCMV Early Events R-HSA-9609690 8.660187e-01 0.062 0 0
Hedgehog 'off' state R-HSA-5610787 8.660323e-01 0.062 0 0
ABC-family proteins mediated transport R-HSA-382556 8.660323e-01 0.062 0 0
Base Excision Repair R-HSA-73884 8.660957e-01 0.062 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 8.683354e-01 0.061 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 8.683354e-01 0.061 0 0
Scavenging by Class A Receptors R-HSA-3000480 8.683354e-01 0.061 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 8.683354e-01 0.061 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 8.683354e-01 0.061 0 0
Interleukin-1 family signaling R-HSA-446652 8.687834e-01 0.061 0 0
SLC-mediated transport of amino acids R-HSA-9958863 8.701189e-01 0.060 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 8.720833e-01 0.059 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 8.724694e-01 0.059 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 8.724930e-01 0.059 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 8.724930e-01 0.059 0 0
DNA Replication R-HSA-69306 8.736807e-01 0.059 0 0
Signaling by FGFR2 R-HSA-5654738 8.739929e-01 0.058 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 8.756255e-01 0.058 0 0
DAP12 signaling R-HSA-2424491 8.756255e-01 0.058 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 8.756255e-01 0.058 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 8.756255e-01 0.058 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.756255e-01 0.058 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 8.780400e-01 0.056 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 8.784590e-01 0.056 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 8.784590e-01 0.056 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 8.784590e-01 0.056 0 0
Scavenging by Class B Receptors R-HSA-3000471 8.784590e-01 0.056 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 8.784590e-01 0.056 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 8.784590e-01 0.056 0 0
Fibronectin matrix formation R-HSA-1566977 8.784590e-01 0.056 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 8.784590e-01 0.056 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 8.784590e-01 0.056 0 0
Synthesis of PG R-HSA-1483148 8.784590e-01 0.056 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 8.784590e-01 0.056 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 8.784590e-01 0.056 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 8.787561e-01 0.056 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 8.829193e-01 0.054 0 0
TNF signaling R-HSA-75893 8.829193e-01 0.054 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 8.850662e-01 0.053 0 0
Cargo concentration in the ER R-HSA-5694530 8.850662e-01 0.053 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 8.850662e-01 0.053 0 0
Signaling by SCF-KIT R-HSA-1433557 8.850844e-01 0.053 0 0
Signaling by FGFR4 R-HSA-5654743 8.850844e-01 0.053 0 0
TBC/RABGAPs R-HSA-8854214 8.850844e-01 0.053 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 8.900720e-01 0.051 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 8.900720e-01 0.051 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 8.900720e-01 0.051 0 0
Glycogen storage diseases R-HSA-3229121 8.900720e-01 0.051 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 8.900720e-01 0.051 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 8.900720e-01 0.051 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 8.900720e-01 0.051 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.900720e-01 0.051 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.924516e-01 0.049 0 0
Proteasome assembly R-HSA-9907900 8.927239e-01 0.049 0 0
G1 Phase R-HSA-69236 8.927239e-01 0.049 0 0
Cyclin D associated events in G1 R-HSA-69231 8.927239e-01 0.049 0 0
Signaling by WNT in cancer R-HSA-4791275 8.938391e-01 0.049 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 8.938391e-01 0.049 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.938391e-01 0.049 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.940847e-01 0.049 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.940847e-01 0.049 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 8.955008e-01 0.048 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 8.965768e-01 0.047 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 8.999044e-01 0.046 0 0
Signaling by FGFR3 R-HSA-5654741 8.999044e-01 0.046 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 8.999044e-01 0.046 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 8.999044e-01 0.046 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 8.999044e-01 0.046 0 0
Synaptic adhesion-like molecules R-HSA-8849932 9.005760e-01 0.045 0 0
Polo-like kinase mediated events R-HSA-156711 9.005760e-01 0.045 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 9.005760e-01 0.045 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 9.006761e-01 0.045 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 9.019855e-01 0.045 0 0
Regulation of necroptotic cell death R-HSA-5675482 9.019855e-01 0.045 0 0
Cardiogenesis R-HSA-9733709 9.019855e-01 0.045 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.022178e-01 0.045 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 9.022627e-01 0.045 0 0
Regulation of beta-cell development R-HSA-186712 9.028648e-01 0.044 0 0
SARS-CoV-1-host interactions R-HSA-9692914 9.038396e-01 0.044 0 0
Formation of a pool of free 40S subunits R-HSA-72689 9.056317e-01 0.043 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.066485e-01 0.043 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.066485e-01 0.043 0 0
Regulation of TNFR1 signaling R-HSA-5357905 9.066485e-01 0.043 0 0
Signaling by Hedgehog R-HSA-5358351 9.067980e-01 0.042 0 0
Ca2+ pathway R-HSA-4086398 9.077893e-01 0.042 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.085545e-01 0.042 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.095451e-01 0.041 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 9.095451e-01 0.041 1 1
Vpu mediated degradation of CD4 R-HSA-180534 9.095451e-01 0.041 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 9.095451e-01 0.041 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 9.095451e-01 0.041 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 9.100769e-01 0.041 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 9.100769e-01 0.041 0 0
Germ layer formation at gastrulation R-HSA-9754189 9.100769e-01 0.041 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.100769e-01 0.041 0 0
Maturation of nucleoprotein R-HSA-9694631 9.100769e-01 0.041 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 9.100769e-01 0.041 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.103744e-01 0.041 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 9.128229e-01 0.040 0 0
Synthesis of PC R-HSA-1483191 9.129783e-01 0.040 1 1
Regulation of RUNX2 expression and activity R-HSA-8939902 9.144337e-01 0.039 0 0
MAP kinase activation R-HSA-450294 9.144337e-01 0.039 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 9.156404e-01 0.038 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 9.156404e-01 0.038 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 9.165556e-01 0.038 0 0
eNOS activation R-HSA-203615 9.165556e-01 0.038 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 9.165556e-01 0.038 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.165556e-01 0.038 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.165556e-01 0.038 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.165556e-01 0.038 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.165556e-01 0.038 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.165556e-01 0.038 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 9.170392e-01 0.038 0 0
Interleukin-12 family signaling R-HSA-447115 9.180929e-01 0.037 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.186704e-01 0.037 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 9.186704e-01 0.037 0 0
Glycogen synthesis R-HSA-3322077 9.186704e-01 0.037 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 9.186704e-01 0.037 0 0
Negative regulation of MET activity R-HSA-6807004 9.186704e-01 0.037 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.186704e-01 0.037 0 0
Nephrin family interactions R-HSA-373753 9.186704e-01 0.037 0 0
Pregnenolone biosynthesis R-HSA-196108 9.186704e-01 0.037 0 0
Signaling by NODAL R-HSA-1181150 9.186704e-01 0.037 0 0
Co-stimulation by CD28 R-HSA-389356 9.189153e-01 0.037 0 0
NGF-stimulated transcription R-HSA-9031628 9.189153e-01 0.037 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 9.197439e-01 0.036 0 0
Cellular response to chemical stress R-HSA-9711123 9.221635e-01 0.035 1 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.230529e-01 0.035 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.230529e-01 0.035 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.230529e-01 0.035 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.230529e-01 0.035 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.230529e-01 0.035 0 0
Regulation of Apoptosis R-HSA-169911 9.230529e-01 0.035 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.230529e-01 0.035 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 9.244800e-01 0.034 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 9.244800e-01 0.034 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.244800e-01 0.034 0 0
Circadian clock R-HSA-9909396 9.258300e-01 0.033 1 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 9.264431e-01 0.033 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 9.264431e-01 0.033 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 9.264431e-01 0.033 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 9.264431e-01 0.033 0 0
Signalling to RAS R-HSA-167044 9.264431e-01 0.033 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 9.264431e-01 0.033 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 9.264431e-01 0.033 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.264431e-01 0.033 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 9.269421e-01 0.033 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 9.269421e-01 0.033 0 0
Glycolysis R-HSA-70171 9.273499e-01 0.033 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.290710e-01 0.032 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.290710e-01 0.032 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.290710e-01 0.032 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.290710e-01 0.032 0 0
G1/S-Specific Transcription R-HSA-69205 9.290710e-01 0.032 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.291516e-01 0.032 0 0
Regulation of RAS by GAPs R-HSA-5658442 9.296927e-01 0.032 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.304077e-01 0.031 0 0
MHC class II antigen presentation R-HSA-2132295 9.304077e-01 0.031 0 0
ABC transporter disorders R-HSA-5619084 9.315037e-01 0.031 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 9.321967e-01 0.030 0 0
CS-GAG biosynthesis R-HSA-2022870 9.334734e-01 0.030 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.334734e-01 0.030 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 9.334734e-01 0.030 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 9.334734e-01 0.030 0 0
Attachment and Entry R-HSA-9694614 9.334734e-01 0.030 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.334734e-01 0.030 0 0
Assembly Of The HIV Virion R-HSA-175474 9.334734e-01 0.030 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.345725e-01 0.029 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.345927e-01 0.029 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.346421e-01 0.029 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.346421e-01 0.029 0 0
Metabolism of folate and pterines R-HSA-196757 9.346421e-01 0.029 0 0
Developmental Cell Lineages R-HSA-9734767 9.379363e-01 0.028 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.382272e-01 0.028 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 9.393527e-01 0.027 0 0
MET promotes cell motility R-HSA-8875878 9.397966e-01 0.027 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.397966e-01 0.027 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 9.397966e-01 0.027 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 9.398321e-01 0.027 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.398321e-01 0.027 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 9.398321e-01 0.027 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 9.398321e-01 0.027 0 0
LDL clearance R-HSA-8964038 9.398321e-01 0.027 0 0
Signaling by KIT in disease R-HSA-9669938 9.398321e-01 0.027 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 9.398321e-01 0.027 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 9.398321e-01 0.027 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 9.398321e-01 0.027 0 0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy R-HSA-9857377 9.398321e-01 0.027 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.416808e-01 0.026 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 9.419231e-01 0.026 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.445634e-01 0.025 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.445634e-01 0.025 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.445634e-01 0.025 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 9.455834e-01 0.024 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 9.455834e-01 0.024 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 9.455834e-01 0.024 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 9.455834e-01 0.024 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.455834e-01 0.024 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 9.473968e-01 0.023 0 0
Neddylation R-HSA-8951664 9.486202e-01 0.023 0 0
Glycogen metabolism R-HSA-8982491 9.489693e-01 0.023 0 0
rRNA processing in the mitochondrion R-HSA-8868766 9.489693e-01 0.023 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.489693e-01 0.023 0 0
Interleukin-2 family signaling R-HSA-451927 9.489693e-01 0.023 0 0
Interferon Signaling R-HSA-913531 9.494056e-01 0.023 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.507853e-01 0.022 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.507853e-01 0.022 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 9.507853e-01 0.022 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 9.507853e-01 0.022 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.507853e-01 0.022 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.507853e-01 0.022 0 0
Neurodegenerative Diseases R-HSA-8863678 9.507853e-01 0.022 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 9.507853e-01 0.022 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.510295e-01 0.022 0 0
Signaling by NOTCH3 R-HSA-9012852 9.511233e-01 0.022 0 0
COPII-mediated vesicle transport R-HSA-204005 9.526292e-01 0.021 0 0
Interleukin-17 signaling R-HSA-448424 9.526292e-01 0.021 0 0
Co-inhibition by PD-1 R-HSA-389948 9.526760e-01 0.021 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.528436e-01 0.021 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.530399e-01 0.021 0 0
FLT3 Signaling R-HSA-9607240 9.530399e-01 0.021 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.530399e-01 0.021 0 0
Eukaryotic Translation Termination R-HSA-72764 9.538317e-01 0.021 0 0
Signaling by FGFR1 R-HSA-5654736 9.546023e-01 0.020 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.554901e-01 0.020 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 9.554901e-01 0.020 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.554901e-01 0.020 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.554901e-01 0.020 0 0
Laminin interactions R-HSA-3000157 9.554901e-01 0.020 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.556251e-01 0.020 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 9.557261e-01 0.020 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.567988e-01 0.019 0 0
Intra-Golgi traffic R-HSA-6811438 9.567988e-01 0.019 0 0
Negative regulation of MAPK pathway R-HSA-5675221 9.567988e-01 0.019 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 9.597455e-01 0.018 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 9.597455e-01 0.018 0 0
TRP channels R-HSA-3295583 9.597455e-01 0.018 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.602686e-01 0.018 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.602686e-01 0.018 0 0
Depyrimidination R-HSA-73928 9.602686e-01 0.018 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 9.602686e-01 0.018 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 9.602686e-01 0.018 0 0
Signaling by FGFR R-HSA-190236 9.613897e-01 0.017 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.629440e-01 0.016 0 0
RAF/MAP kinase cascade R-HSA-5673001 9.632590e-01 0.016 0 0
Defective pyroptosis R-HSA-9710421 9.634700e-01 0.016 0 0
Packaging Of Telomere Ends R-HSA-171306 9.635942e-01 0.016 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.635942e-01 0.016 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.635942e-01 0.016 0 0
Triglyceride biosynthesis R-HSA-75109 9.635942e-01 0.016 0 0
Synthesis of PE R-HSA-1483213 9.635942e-01 0.016 0 0
Signaling by BMP R-HSA-201451 9.635942e-01 0.016 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 9.635942e-01 0.016 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.635942e-01 0.016 1 1
tRNA processing R-HSA-72306 9.653639e-01 0.015 0 0
Peptide chain elongation R-HSA-156902 9.655514e-01 0.015 0 0
tRNA Aminoacylation R-HSA-379724 9.663278e-01 0.015 0 0
Iron uptake and transport R-HSA-917937 9.663345e-01 0.015 0 0
DAP12 interactions R-HSA-2172127 9.664228e-01 0.015 0 0
Gap junction trafficking R-HSA-190828 9.664228e-01 0.015 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.664228e-01 0.015 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.664228e-01 0.015 0 0
Amine ligand-binding receptors R-HSA-375280 9.664228e-01 0.015 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 9.670752e-01 0.015 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 9.670752e-01 0.015 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 9.670752e-01 0.015 0 0
Iron assimilation using enterobactin R-HSA-9638334 9.670752e-01 0.015 0 0
Pyrimidine salvage R-HSA-73614 9.670752e-01 0.015 0 0
Pyroptosis R-HSA-5620971 9.670752e-01 0.015 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 9.691451e-01 0.014 0 0
Integration of energy metabolism R-HSA-163685 9.693153e-01 0.014 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 9.693335e-01 0.014 0 0
Downstream TCR signaling R-HSA-202424 9.697325e-01 0.013 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 9.702235e-01 0.013 0 0
DNA methylation R-HSA-5334118 9.702235e-01 0.013 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.702235e-01 0.013 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 9.702235e-01 0.013 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.702235e-01 0.013 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.707020e-01 0.013 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.714360e-01 0.013 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.716540e-01 0.012 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 9.719083e-01 0.012 0 0
Integrin cell surface interactions R-HSA-216083 9.726814e-01 0.012 0 0
Interleukin-10 signaling R-HSA-6783783 9.726814e-01 0.012 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 9.730709e-01 0.012 0 0
Neurotransmitter clearance R-HSA-112311 9.730709e-01 0.012 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 9.731787e-01 0.012 0 0
Signaling by PTK6 R-HSA-8848021 9.731787e-01 0.012 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 9.731787e-01 0.012 0 0
HCMV Infection R-HSA-9609646 9.744243e-01 0.011 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 9.756462e-01 0.011 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 9.756462e-01 0.011 0 0
EGFR downregulation R-HSA-182971 9.756462e-01 0.011 0 0
Intraflagellar transport R-HSA-5620924 9.760942e-01 0.011 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.760942e-01 0.011 0 0
Signaling by MET R-HSA-6806834 9.762699e-01 0.010 0 0
PKR-mediated signaling R-HSA-9833482 9.762699e-01 0.010 0 0
Glucose metabolism R-HSA-70326 9.765388e-01 0.010 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.765923e-01 0.010 0 0
Toll-like Receptor Cascades R-HSA-168898 9.768231e-01 0.010 0 0
Platelet homeostasis R-HSA-418346 9.777952e-01 0.010 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 9.779754e-01 0.010 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.786929e-01 0.009 0 0
PPARA activates gene expression R-HSA-1989781 9.787561e-01 0.009 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.791497e-01 0.009 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.798579e-01 0.009 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 9.800819e-01 0.009 0 0
G-protein beta:gamma signalling R-HSA-397795 9.800819e-01 0.009 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.802457e-01 0.009 0 0
Leishmania infection R-HSA-9658195 9.806162e-01 0.009 0 0
Parasitic Infection Pathways R-HSA-9824443 9.806162e-01 0.009 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.808312e-01 0.008 0 0
The phototransduction cascade R-HSA-2514856 9.815175e-01 0.008 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.815175e-01 0.008 0 0
Regulated Necrosis R-HSA-5218859 9.817494e-01 0.008 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.817943e-01 0.008 0 0
Striated Muscle Contraction R-HSA-390522 9.819871e-01 0.008 0 0
CS/DS degradation R-HSA-2024101 9.819871e-01 0.008 0 0
Effects of PIP2 hydrolysis R-HSA-114508 9.819871e-01 0.008 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.826867e-01 0.008 0 0
SARS-CoV Infections R-HSA-9679506 9.830789e-01 0.007 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.837101e-01 0.007 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.837101e-01 0.007 1 1
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 9.837101e-01 0.007 0 0
RA biosynthesis pathway R-HSA-5365859 9.837101e-01 0.007 0 0
Translation R-HSA-72766 9.841726e-01 0.007 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.843840e-01 0.007 0 0
Transmission across Chemical Synapses R-HSA-112315 9.845303e-01 0.007 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 9.852134e-01 0.006 0 0
Oncogene Induced Senescence R-HSA-2559585 9.852684e-01 0.006 0 0
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775 9.852684e-01 0.006 0 0
FOXO-mediated transcription R-HSA-9614085 9.854582e-01 0.006 0 0
Retinoid metabolism and transport R-HSA-975634 9.855607e-01 0.006 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.857384e-01 0.006 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 9.864190e-01 0.006 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 9.864190e-01 0.006 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 9.864190e-01 0.006 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.864294e-01 0.006 1 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 9.866520e-01 0.006 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 9.866777e-01 0.006 0 0
GPVI-mediated activation cascade R-HSA-114604 9.866777e-01 0.006 0 0
Selenocysteine synthesis R-HSA-2408557 9.873185e-01 0.006 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.879523e-01 0.005 0 0
Cleavage of the damaged purine R-HSA-110331 9.879523e-01 0.005 0 0
Platelet degranulation R-HSA-114608 9.880065e-01 0.005 0 0
ER-Phagosome pathway R-HSA-1236974 9.884629e-01 0.005 0 0
Leishmania phagocytosis R-HSA-9664417 9.886560e-01 0.005 0 0
Parasite infection R-HSA-9664407 9.886560e-01 0.005 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.886560e-01 0.005 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.889521e-01 0.005 0 0
Viral mRNA Translation R-HSA-192823 9.889521e-01 0.005 0 0
SLC transporter disorders R-HSA-5619102 9.889849e-01 0.005 0 0
tRNA processing in the mitochondrion R-HSA-6785470 9.891050e-01 0.005 0 0
Depurination R-HSA-73927 9.891050e-01 0.005 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.899343e-01 0.004 0 0
Post-translational protein modification R-HSA-597592 9.900307e-01 0.004 0 0
RAS processing R-HSA-9648002 9.901475e-01 0.004 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.901475e-01 0.004 0 0
Peroxisomal protein import R-HSA-9033241 9.907782e-01 0.004 0 0
Tryptophan catabolism R-HSA-71240 9.910903e-01 0.004 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.910903e-01 0.004 0 0
HCMV Late Events R-HSA-9610379 9.910983e-01 0.004 0 0
Cardiac conduction R-HSA-5576891 9.912471e-01 0.004 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.912718e-01 0.004 0 0
Metabolism of polyamines R-HSA-351202 9.915529e-01 0.004 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.916078e-01 0.004 0 0
G alpha (s) signalling events R-HSA-418555 9.917016e-01 0.004 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.917114e-01 0.004 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.919429e-01 0.004 0 0
Maturation of spike protein R-HSA-9694548 9.919429e-01 0.004 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.920328e-01 0.003 0 0
Aquaporin-mediated transport R-HSA-445717 9.922638e-01 0.003 0 0
Translation of Structural Proteins R-HSA-9683701 9.927140e-01 0.003 0 0
Stimuli-sensing channels R-HSA-2672351 9.927379e-01 0.003 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.929161e-01 0.003 0 0
SARS-CoV-1 Infection R-HSA-9678108 9.934091e-01 0.003 0 0
Activation of GABAB receptors R-HSA-991365 9.934113e-01 0.003 0 0
GABA B receptor activation R-HSA-977444 9.934113e-01 0.003 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.934113e-01 0.003 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.934879e-01 0.003 0 0
Amyloid fiber formation R-HSA-977225 9.934879e-01 0.003 0 0
Ion channel transport R-HSA-983712 9.935060e-01 0.003 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.936573e-01 0.003 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 9.940419e-01 0.003 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.940419e-01 0.003 0 0
Phospholipid metabolism R-HSA-1483257 9.940717e-01 0.003 1 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 9.945208e-01 0.002 0 0
Cellular response to hypoxia R-HSA-1234174 9.945663e-01 0.002 0 0
Surfactant metabolism R-HSA-5683826 9.946122e-01 0.002 0 0
Methylation R-HSA-156581 9.946122e-01 0.002 0 0
Developmental Biology R-HSA-1266738 9.946464e-01 0.002 1 0
Regulation of insulin secretion R-HSA-422356 9.949291e-01 0.002 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.951060e-01 0.002 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.951239e-01 0.002 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.951279e-01 0.002 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.955943e-01 0.002 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.961883e-01 0.002 0 0
Muscle contraction R-HSA-397014 9.963705e-01 0.002 0 0
Diseases of programmed cell death R-HSA-9645723 9.966072e-01 0.001 0 0
Interferon gamma signaling R-HSA-877300 9.967364e-01 0.001 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.967424e-01 0.001 0 0
ECM proteoglycans R-HSA-3000178 9.968158e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.968158e-01 0.001 0 0
Metabolism of cofactors R-HSA-8978934 9.968158e-01 0.001 0 0
Azathioprine ADME R-HSA-9748787 9.970544e-01 0.001 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.973364e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.975669e-01 0.001 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 9.975915e-01 0.001 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.976227e-01 0.001 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.977559e-01 0.001 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.977559e-01 0.001 0 0
Signaling by Interleukins R-HSA-449147 9.977757e-01 0.001 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.978270e-01 0.001 0 0
Neuronal System R-HSA-112316 9.978934e-01 0.001 0 0
Translation of Structural Proteins R-HSA-9694635 9.981429e-01 0.001 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.982194e-01 0.001 0 0
G alpha (z) signalling events R-HSA-418597 9.982194e-01 0.001 0 0
Mitochondrial translation elongation R-HSA-5389840 9.985217e-01 0.001 0 0
Synthesis of PA R-HSA-1483166 9.985441e-01 0.001 0 0
Mitochondrial translation initiation R-HSA-5368286 9.987503e-01 0.001 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.987823e-01 0.001 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.987823e-01 0.001 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.987937e-01 0.001 1 0
Triglyceride metabolism R-HSA-8979227 9.988097e-01 0.001 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.988097e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.988513e-01 0.000 0 0
GABA receptor activation R-HSA-977443 9.989238e-01 0.000 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.989238e-01 0.000 0 0
Viral Infection Pathways R-HSA-9824446 9.989838e-01 0.000 1 0
Collagen degradation R-HSA-1442490 9.990269e-01 0.000 0 0
Nucleotide salvage R-HSA-8956321 9.990269e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.990886e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.992044e-01 0.000 0 0
RSV-host interactions R-HSA-9833110 9.993090e-01 0.000 0 0
Cytokine Signaling in Immune system R-HSA-1280215 9.993956e-01 0.000 0 0
Protein localization R-HSA-9609507 9.994231e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.994568e-01 0.000 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.994683e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.994683e-01 0.000 0 0
Metabolism of steroid hormones R-HSA-196071 9.994683e-01 0.000 0 0
Formation of the cornified envelope R-HSA-6809371 9.994808e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.995492e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.995863e-01 0.000 0 0
Metal ion assimilation from the host R-HSA-9638482 9.996447e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.996718e-01 0.000 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.996788e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.996844e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.997096e-01 0.000 0 0
Selenoamino acid metabolism R-HSA-2408522 9.997461e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.997504e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.997512e-01 0.000 0 0
Interferon alpha/beta signaling R-HSA-909733 9.997738e-01 0.000 0 0
Adaptive Immune System R-HSA-1280218 9.997890e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.998029e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.998414e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999042e-01 0.000 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.999292e-01 0.000 0 0
Pyruvate metabolism R-HSA-70268 9.999360e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.999488e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999488e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.999679e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.999684e-01 0.000 0 0
Collagen formation R-HSA-1474290 9.999715e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.999742e-01 0.000 0 0
Hemostasis R-HSA-109582 9.999774e-01 0.000 0 0
Potassium Channels R-HSA-1296071 9.999789e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999804e-01 0.000 0 0
Neutrophil degranulation R-HSA-6798695 9.999817e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999861e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999868e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999884e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999901e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999915e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999940e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.999947e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.999949e-01 0.000 1 0
Antimicrobial peptides R-HSA-6803157 9.999958e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999970e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999982e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999988e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999990e-01 0.000 0 0
Regulation of Complement cascade R-HSA-977606 9.999992e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999992e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999995e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999996e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999997e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999997e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999998e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.999998e-01 0.000 1 0
Complement cascade R-HSA-166658 9.999999e-01 0.000 0 0
Disease R-HSA-1643685 1.000000e+00 0.000 1 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Respiratory electron transport R-HSA-611105 1.000000e+00 0.000 0 0
GPCR downstream signalling R-HSA-388396 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Metabolism of nucleotides R-HSA-15869 1.000000e+00 0.000 0 0
G alpha (q) signalling events R-HSA-416476 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Immune System R-HSA-168256 1.000000e+00 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Innate Immune System R-HSA-168249 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 1 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 1 0
GPCR ligand binding R-HSA-500792 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
mRNA Splicing - Major Pathway R-HSA-72163 1.110223e-16 15.955 0 0
mRNA Splicing R-HSA-72172 1.110223e-16 15.955 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.110223e-16 15.955 0 0
Metabolism of RNA R-HSA-8953854 1.110223e-16 15.955 0 0
Attenuation phase R-HSA-3371568 9.936496e-14 13.003 0 0
HSF1-dependent transactivation R-HSA-3371571 2.087663e-12 11.680 0 0
Cellular response to heat stress R-HSA-3371556 7.516234e-10 9.124 0 0
HSF1 activation R-HSA-3371511 1.783512e-09 8.749 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 7.125993e-09 8.147 0 0
Chromatin organization R-HSA-4839726 2.122621e-07 6.673 0 0
Chromatin modifying enzymes R-HSA-3247509 2.636254e-07 6.579 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 3.736737e-07 6.428 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 8.091078e-07 6.092 0 0
Cell Cycle R-HSA-1640170 1.789753e-06 5.747 1 0
rRNA processing R-HSA-72312 3.286789e-05 4.483 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 4.372964e-05 4.359 0 0
Epigenetic regulation of gene expression R-HSA-212165 5.195984e-05 4.284 0 0
Estrogen-dependent gene expression R-HSA-9018519 6.536037e-05 4.185 0 0
mRNA 3'-end processing R-HSA-72187 7.534864e-05 4.123 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 8.350042e-05 4.078 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.335693e-04 3.874 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.059990e-04 3.686 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 2.220845e-04 3.653 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.578898e-04 3.589 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 3.036224e-04 3.518 0 0
Regulation of PTEN gene transcription R-HSA-8943724 2.846729e-04 3.546 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.846729e-04 3.546 0 0
Cell Cycle, Mitotic R-HSA-69278 2.693823e-04 3.570 1 0
RNA Polymerase II Transcription Termination R-HSA-73856 3.309349e-04 3.480 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 4.566840e-04 3.340 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 5.420128e-04 3.266 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 6.823990e-04 3.166 0 0
DNA Double-Strand Break Repair R-HSA-5693532 8.109050e-04 3.091 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 9.386297e-04 3.028 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.109046e-03 2.955 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.126311e-03 2.948 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.100145e-03 2.959 0 0
Repression of WNT target genes R-HSA-4641265 1.533872e-03 2.814 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.614396e-03 2.792 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.816520e-03 2.741 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 3.652943e-03 2.437 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 3.652943e-03 2.437 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 3.652943e-03 2.437 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 3.652943e-03 2.437 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 3.652943e-03 2.437 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 3.652943e-03 2.437 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 3.652943e-03 2.437 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 3.652943e-03 2.437 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 3.652943e-03 2.437 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 3.652943e-03 2.437 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 3.652943e-03 2.437 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 3.357376e-03 2.474 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 2.742655e-03 2.562 0 0
Homology Directed Repair R-HSA-5693538 3.174376e-03 2.498 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 3.418068e-03 2.466 0 0
M Phase R-HSA-68886 2.781619e-03 2.556 1 0
Transcriptional Regulation by E2F6 R-HSA-8953750 3.078382e-03 2.512 0 0
Gene expression (Transcription) R-HSA-74160 2.970851e-03 2.527 1 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 4.162636e-03 2.381 0 0
Cell Cycle Checkpoints R-HSA-69620 5.047088e-03 2.297 0 0
ESR-mediated signaling R-HSA-8939211 4.972485e-03 2.303 0 0
RNA Polymerase I Transcription R-HSA-73864 6.848372e-03 2.164 0 0
DNA Repair R-HSA-73894 6.766504e-03 2.170 0 0
G2/M Checkpoints R-HSA-69481 6.880780e-03 2.162 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 7.419770e-03 2.130 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 7.419770e-03 2.130 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 7.086745e-03 2.150 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 8.737139e-03 2.059 0 0
PTEN Regulation R-HSA-6807070 9.211560e-03 2.036 1 0
HDACs deacetylate histones R-HSA-3214815 9.605366e-03 2.017 0 0
S Phase R-HSA-69242 9.249946e-03 2.034 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.006652e-02 1.997 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.011428e-02 1.995 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.011428e-02 1.995 0 0
Nuclear RNA decay R-HSA-9930044 1.061349e-02 1.974 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 1.061349e-02 1.974 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 1.056076e-02 1.976 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.061349e-02 1.974 1 1
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 1.103636e-02 1.957 0 0
Cellular responses to stress R-HSA-2262752 1.131864e-02 1.946 1 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.141496e-02 1.943 0 0
Resolution of D-Loop Structures R-HSA-5693537 1.219030e-02 1.914 0 0
Mitotic Prometaphase R-HSA-68877 1.253917e-02 1.902 1 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.309790e-02 1.883 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.272800e-02 1.895 0 0
Unwinding of DNA R-HSA-176974 1.368918e-02 1.864 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.302424e-02 1.885 1 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.302424e-02 1.885 1 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.422077e-02 1.847 1 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.452009e-02 1.838 0 0
HIV Life Cycle R-HSA-162587 1.593404e-02 1.798 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 1.784913e-02 1.748 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 1.795054e-02 1.746 0 0
RNA Polymerase III Transcription R-HSA-74158 1.795054e-02 1.746 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.837957e-02 1.736 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.895158e-02 1.722 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.937942e-02 1.713 0 0
Smooth Muscle Contraction R-HSA-445355 1.937942e-02 1.713 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.992081e-02 1.701 0 0
Notch-HLH transcription pathway R-HSA-350054 2.087445e-02 1.680 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 2.102808e-02 1.677 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 2.087445e-02 1.680 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 2.063252e-02 1.685 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.189755e-02 1.660 0 0
Semaphorin interactions R-HSA-373755 2.114906e-02 1.675 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 2.273763e-02 1.643 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 2.345084e-02 1.630 0 0
G2/M DNA damage checkpoint R-HSA-69473 2.432292e-02 1.614 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.485833e-02 1.605 1 0
Signaling by Hippo R-HSA-2028269 2.704048e-02 1.568 0 0
G0 and Early G1 R-HSA-1538133 2.708813e-02 1.567 0 0
Adherens junctions interactions R-HSA-418990 2.659125e-02 1.575 1 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 2.808504e-02 1.552 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 2.708813e-02 1.567 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 2.821372e-02 1.550 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.052236e-02 1.515 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.052236e-02 1.515 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 3.080795e-02 1.511 0 0
Deubiquitination R-HSA-5688426 3.167891e-02 1.499 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 3.181103e-02 1.497 0 0
HDMs demethylate histones R-HSA-3214842 3.197729e-02 1.495 0 0
Sema4D in semaphorin signaling R-HSA-400685 3.197729e-02 1.495 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 3.356597e-02 1.474 0 0
Cellular responses to stimuli R-HSA-8953897 3.629614e-02 1.440 1 0
MITF-M-dependent gene expression R-HSA-9856651 3.373985e-02 1.472 0 0
Recycling of eIF2:GDP R-HSA-72731 4.105611e-02 1.387 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 3.707623e-02 1.431 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 4.118013e-02 1.385 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 4.118013e-02 1.385 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 4.118013e-02 1.385 0 0
Separation of Sister Chromatids R-HSA-2467813 3.978180e-02 1.400 0 0
Late Phase of HIV Life Cycle R-HSA-162599 3.851628e-02 1.414 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 4.018818e-02 1.396 0 0
Signaling by ALK in cancer R-HSA-9700206 4.018818e-02 1.396 0 0
Ub-specific processing proteases R-HSA-5689880 3.837033e-02 1.416 0 0
HIV Infection R-HSA-162906 3.900406e-02 1.409 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 3.887699e-02 1.410 1 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.118013e-02 1.385 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 4.120031e-02 1.385 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 4.129820e-02 1.384 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 4.129820e-02 1.384 0 0
Cap-dependent Translation Initiation R-HSA-72737 4.175313e-02 1.379 0 0
Eukaryotic Translation Initiation R-HSA-72613 4.175313e-02 1.379 0 0
Cell-cell junction organization R-HSA-421270 4.183135e-02 1.378 1 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 4.284539e-02 1.368 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 4.284539e-02 1.368 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 4.284539e-02 1.368 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 4.284539e-02 1.368 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 4.284539e-02 1.368 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 4.284539e-02 1.368 0 0
HATs acetylate histones R-HSA-3214847 4.334287e-02 1.363 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.334287e-02 1.363 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.487741e-02 1.348 0 0
HIV elongation arrest and recovery R-HSA-167287 4.634732e-02 1.334 0 0
Pausing and recovery of HIV elongation R-HSA-167290 4.634732e-02 1.334 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 4.642926e-02 1.333 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 5.176801e-02 1.286 0 0
EPH-Ephrin signaling R-HSA-2682334 4.970654e-02 1.304 0 0
Regulation of endogenous retroelements R-HSA-9842860 5.181751e-02 1.286 0 0
Mitotic Prophase R-HSA-68875 5.193761e-02 1.285 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 5.204500e-02 1.284 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 5.553551e-02 1.255 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 5.747696e-02 1.241 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 5.747696e-02 1.241 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 5.747696e-02 1.241 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 5.591745e-02 1.252 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 5.591745e-02 1.252 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 5.591745e-02 1.252 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 5.712597e-02 1.243 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 5.712597e-02 1.243 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.074064e-02 1.217 0 0
Activation of the pre-replicative complex R-HSA-68962 5.783950e-02 1.238 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 5.747696e-02 1.241 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 5.473284e-02 1.262 0 0
Mitotic Anaphase R-HSA-68882 6.070944e-02 1.217 0 0
Nuclear Envelope Breakdown R-HSA-2980766 6.164433e-02 1.210 0 0
Regulation of TP53 Activity R-HSA-5633007 5.454433e-02 1.263 1 0
Protein ubiquitination R-HSA-8852135 5.396061e-02 1.268 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 5.591745e-02 1.252 0 0
Signaling by NOTCH1 R-HSA-1980143 5.770451e-02 1.239 0 0
Apoptotic execution phase R-HSA-75153 5.537839e-02 1.257 0 0
Unfolded Protein Response (UPR) R-HSA-381119 5.370438e-02 1.270 0 0
DNA Double Strand Break Response R-HSA-5693606 6.199249e-02 1.208 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 6.199249e-02 1.208 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 6.278586e-02 1.202 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 6.278586e-02 1.202 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 6.278586e-02 1.202 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 6.303480e-02 1.200 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.322370e-02 1.199 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 6.322370e-02 1.199 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.322370e-02 1.199 0 0
ALK mutants bind TKIs R-HSA-9700645 6.368493e-02 1.196 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 7.267773e-02 1.139 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 7.104082e-02 1.148 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 7.104082e-02 1.148 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 6.862589e-02 1.164 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 6.862589e-02 1.164 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 6.638429e-02 1.178 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 7.653481e-02 1.116 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 7.585390e-02 1.120 0 0
Nucleotide Excision Repair R-HSA-5696398 6.480154e-02 1.188 0 0
HIV Transcription Elongation R-HSA-167169 6.862589e-02 1.164 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 7.478023e-02 1.126 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 6.862589e-02 1.164 0 0
snRNP Assembly R-HSA-191859 7.134742e-02 1.147 0 0
Metabolism of non-coding RNA R-HSA-194441 7.134742e-02 1.147 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 7.618888e-02 1.118 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 6.862589e-02 1.164 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 6.862589e-02 1.164 0 0
DNA strand elongation R-HSA-69190 7.089134e-02 1.149 0 0
Cell junction organization R-HSA-446728 7.237389e-02 1.140 1 0
PKMTs methylate histone lysines R-HSA-3214841 7.478023e-02 1.126 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 7.073635e-02 1.150 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 7.653481e-02 1.116 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 7.653481e-02 1.116 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 7.653481e-02 1.116 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 7.653481e-02 1.116 0 0
PKR-mediated signaling R-HSA-9833482 7.437632e-02 1.129 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 7.653481e-02 1.116 0 0
Disorders of Developmental Biology R-HSA-9675151 7.656436e-02 1.116 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 7.656436e-02 1.116 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 7.674280e-02 1.115 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 7.685437e-02 1.114 0 0
FGFR1 mutant receptor activation R-HSA-1839124 7.800201e-02 1.108 0 0
Mitotic Spindle Checkpoint R-HSA-69618 8.284879e-02 1.082 0 0
Striated Muscle Contraction R-HSA-390522 8.549928e-02 1.068 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 8.591720e-02 1.066 0 0
Long-term potentiation R-HSA-9620244 8.818347e-02 1.055 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 8.818347e-02 1.055 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 8.844990e-02 1.053 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 9.086836e-02 1.042 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 9.129085e-02 1.040 0 0
Nuclear import of Rev protein R-HSA-180746 9.337884e-02 1.030 0 0
Meiotic synapsis R-HSA-1221632 9.487739e-02 1.023 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.059817e-01 0.975 1 1
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 1.103132e-01 0.957 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.072721e-01 0.970 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 1.175132e-01 0.930 0 0
Formation of the Early Elongation Complex R-HSA-113418 1.175132e-01 0.930 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 1.182194e-01 0.927 0 0
Translation initiation complex formation R-HSA-72649 1.015639e-01 0.993 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.058394e-01 0.975 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.026267e-01 0.989 0 0
Chaperone Mediated Autophagy R-HSA-9613829 9.841573e-02 1.007 0 0
Myogenesis R-HSA-525793 9.749058e-02 1.011 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 9.841573e-02 1.007 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.182194e-01 0.927 0 0
RMTs methylate histone arginines R-HSA-3214858 1.025191e-01 0.989 0 0
Specification of the neural plate border R-HSA-9834899 1.103132e-01 0.957 0 0
Host Interactions of HIV factors R-HSA-162909 1.057730e-01 0.976 0 0
Cell-Cell communication R-HSA-1500931 1.111323e-01 0.954 1 0
RNA Polymerase II Transcription R-HSA-73857 1.125780e-01 0.949 1 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.217320e-01 0.915 0 0
Signaling by TGFBR3 R-HSA-9839373 1.182194e-01 0.927 0 0
Toxicity of botulinum toxin type C (botC) R-HSA-5250971 9.882966e-02 1.005 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 9.841573e-02 1.007 0 0
Death Receptor Signaling R-HSA-73887 1.071344e-01 0.970 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 9.882966e-02 1.005 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.219983e-01 0.914 0 0
Disorders of Nervous System Development R-HSA-9697154 1.219983e-01 0.914 0 0
Pervasive developmental disorders R-HSA-9005895 1.219983e-01 0.914 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 1.219983e-01 0.914 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.219983e-01 0.914 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 1.230604e-01 0.910 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 1.230604e-01 0.910 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.230604e-01 0.910 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.230604e-01 0.910 0 0
Transcription of the HIV genome R-HSA-167172 1.260758e-01 0.899 0 0
DARPP-32 events R-HSA-180024 1.281974e-01 0.892 0 0
mRNA Capping R-HSA-72086 1.281974e-01 0.892 0 0
Dual incision in TC-NER R-HSA-6782135 1.308421e-01 0.883 0 0
Signaling by ALK R-HSA-201556 1.382634e-01 0.859 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 1.388313e-01 0.858 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 1.388313e-01 0.858 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.393063e-01 0.856 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.400774e-01 0.854 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.400774e-01 0.854 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.400774e-01 0.854 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.400774e-01 0.854 0 0
UNC93B1 deficiency - HSE R-HSA-5602415 1.400774e-01 0.854 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.400774e-01 0.854 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.400774e-01 0.854 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.400774e-01 0.854 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.400774e-01 0.854 0 0
Autointegration results in viral DNA circles R-HSA-177539 1.485309e-01 0.828 0 0
Regulation of PTEN localization R-HSA-8948747 1.749332e-01 0.757 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.563923e-01 0.806 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 1.495019e-01 0.825 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.781696e-01 0.749 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.508202e-01 0.822 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.508202e-01 0.822 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.749776e-01 0.757 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.749776e-01 0.757 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 1.720822e-01 0.764 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.727935e-01 0.762 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.727935e-01 0.762 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.784213e-01 0.749 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.784213e-01 0.749 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.406320e-01 0.852 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.630395e-01 0.788 0 0
Ca-dependent events R-HSA-111996 1.801327e-01 0.744 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.639868e-01 0.785 0 0
Switching of origins to a post-replicative state R-HSA-69052 1.639868e-01 0.785 0 0
DNA Damage Reversal R-HSA-73942 1.745934e-01 0.758 0 0
NRIF signals cell death from the nucleus R-HSA-205043 1.563923e-01 0.806 0 0
Neurexins and neuroligins R-HSA-6794361 1.720822e-01 0.764 0 0
CHL1 interactions R-HSA-447041 1.749332e-01 0.757 0 0
Cellular Senescence R-HSA-2559583 1.802648e-01 0.744 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.720822e-01 0.764 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 1.485309e-01 0.828 0 0
Protein methylation R-HSA-8876725 1.745934e-01 0.758 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.692193e-01 0.772 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.482706e-01 0.829 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 1.749776e-01 0.757 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 1.749776e-01 0.757 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.749776e-01 0.757 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 1.745934e-01 0.758 0 0
Inositol phosphate metabolism R-HSA-1483249 1.508148e-01 0.822 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 1.749332e-01 0.757 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 1.749332e-01 0.757 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 1.749332e-01 0.757 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.716147e-01 0.765 0 0
Potential therapeutics for SARS R-HSA-9679191 1.409370e-01 0.851 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.805136e-01 0.743 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.863558e-01 0.730 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 1.875757e-01 0.727 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.875757e-01 0.727 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.933478e-01 0.714 0 0
Phosphorylation of the APC/C R-HSA-176412 1.933478e-01 0.714 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.933478e-01 0.714 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 1.933478e-01 0.714 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.933478e-01 0.714 0 0
Synthesis of DNA R-HSA-69239 1.942108e-01 0.712 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.025821e-01 0.693 0 0
Defective TPMT causes TPMT deficiency R-HSA-5578995 2.025821e-01 0.693 0 0
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) R-HSA-5619039 2.025821e-01 0.693 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.025821e-01 0.693 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.025821e-01 0.693 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 2.605470e-01 0.584 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.143017e-01 0.503 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.143017e-01 0.503 0 0
Defective ABCC2 causes DJS R-HSA-5679001 3.143017e-01 0.503 0 0
Invadopodia formation R-HSA-8941237 3.143017e-01 0.503 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 2.294890e-01 0.639 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 3.641516e-01 0.439 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 2.125707e-01 0.672 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 4.103802e-01 0.387 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 4.103802e-01 0.387 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 4.103802e-01 0.387 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 2.520968e-01 0.598 0 0
PKA activation R-HSA-163615 2.520968e-01 0.598 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.722462e-01 0.565 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 3.400209e-01 0.468 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 3.400209e-01 0.468 0 0
Scavenging by Class F Receptors R-HSA-3000484 3.400209e-01 0.468 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 4.532503e-01 0.344 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 4.532503e-01 0.344 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 4.532503e-01 0.344 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 4.532503e-01 0.344 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 4.532503e-01 0.344 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.136919e-01 0.670 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 3.670816e-01 0.435 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 3.129623e-01 0.505 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 2.728191e-01 0.564 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.144464e-01 0.669 0 0
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) R-HSA-5619070 4.930059e-01 0.307 0 0
AURKA Activation by TPX2 R-HSA-8854518 2.005173e-01 0.698 0 0
Deadenylation of mRNA R-HSA-429947 3.943393e-01 0.404 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 5.298729e-01 0.276 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.712072e-01 0.567 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 3.737377e-01 0.427 0 0
Centrosome maturation R-HSA-380287 2.926079e-01 0.534 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 3.130417e-01 0.504 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 3.857185e-01 0.414 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 3.857185e-01 0.414 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.004613e-01 0.397 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 4.943535e-01 0.306 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 4.943535e-01 0.306 0 0
ALKBH3 mediated reversal of alkylation damage R-HSA-112126 5.640611e-01 0.249 0 0
phospho-PLA2 pathway R-HSA-111995 5.640611e-01 0.249 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 5.178259e-01 0.286 0 0
Formation of a pool of free 40S subunits R-HSA-72689 4.071565e-01 0.390 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 4.732198e-01 0.325 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 5.405605e-01 0.267 0 0
ARMS-mediated activation R-HSA-170984 5.957650e-01 0.225 0 0
Lipophagy R-HSA-9613354 5.957650e-01 0.225 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.874601e-01 0.312 1 1
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.874601e-01 0.312 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.874601e-01 0.312 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 5.054709e-01 0.296 0 0
HIV Transcription Initiation R-HSA-167161 5.054709e-01 0.296 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 5.054709e-01 0.296 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 5.287868e-01 0.277 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 4.595715e-01 0.338 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 4.595715e-01 0.338 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 5.155085e-01 0.288 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 5.365658e-01 0.270 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 5.292906e-01 0.276 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 5.837553e-01 0.234 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 5.837553e-01 0.234 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 5.666454e-01 0.247 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 5.666454e-01 0.247 0 0
Nucleosome assembly R-HSA-774815 5.666454e-01 0.247 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 5.811283e-01 0.236 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 5.812735e-01 0.236 0 0
Dual Incision in GG-NER R-HSA-5696400 5.977356e-01 0.223 0 0
Signaling by NOTCH2 R-HSA-1980145 5.977356e-01 0.223 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 3.129623e-01 0.505 0 0
Telomere Extension By Telomerase R-HSA-171319 4.729912e-01 0.325 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 4.244902e-01 0.372 0 0
Aggrephagy R-HSA-9646399 2.831862e-01 0.548 0 0
Signaling by RAF1 mutants R-HSA-9656223 3.121387e-01 0.506 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 3.407851e-01 0.468 0 0
Signaling downstream of RAS mutants R-HSA-9649948 3.857185e-01 0.414 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 3.857185e-01 0.414 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 3.857185e-01 0.414 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 5.472047e-01 0.262 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 5.957650e-01 0.225 0 0
COPI-mediated anterograde transport R-HSA-6807878 5.577237e-01 0.254 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 2.831862e-01 0.548 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 5.640611e-01 0.249 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 4.734812e-01 0.325 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 2.004887e-01 0.698 0 0
Regulation of TP53 Degradation R-HSA-6804757 4.074281e-01 0.390 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 2.294890e-01 0.639 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 3.641516e-01 0.439 0 0
Regulation of gap junction activity R-HSA-191650 3.641516e-01 0.439 0 0
NF-kB is activated and signals survival R-HSA-209560 3.126100e-01 0.505 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 3.400209e-01 0.468 0 0
Signaling by MST1 R-HSA-8852405 4.532503e-01 0.344 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 2.271605e-01 0.644 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 5.640611e-01 0.249 0 0
PIP3 activates AKT signaling R-HSA-1257604 3.491148e-01 0.457 1 0
Post NMDA receptor activation events R-HSA-438064 4.376066e-01 0.359 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.727569e-01 0.564 0 0
Integration of provirus R-HSA-162592 3.126100e-01 0.505 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 3.400209e-01 0.468 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 5.625405e-01 0.250 0 0
CaM pathway R-HSA-111997 2.271605e-01 0.644 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.624460e-01 0.581 1 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.571954e-01 0.340 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 3.510100e-01 0.455 0 0
Calmodulin induced events R-HSA-111933 2.271605e-01 0.644 0 0
Formation of the posterior neural plate R-HSA-9832991 2.849602e-01 0.545 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.103802e-01 0.387 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 2.321799e-01 0.634 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 3.398991e-01 0.469 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.015670e-01 0.696 0 0
PTK6 Expression R-HSA-8849473 5.298729e-01 0.276 0 0
Fanconi Anemia Pathway R-HSA-6783310 3.709563e-01 0.431 0 0
Signaling by RAS mutants R-HSA-6802949 3.857185e-01 0.414 0 0
Intraflagellar transport R-HSA-5620924 4.151648e-01 0.382 0 0
Calcineurin activates NFAT R-HSA-2025928 5.957650e-01 0.225 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 4.269842e-01 0.370 0 0
RAF activation R-HSA-5673000 5.977356e-01 0.223 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 4.571954e-01 0.340 0 0
Generation of second messenger molecules R-HSA-202433 4.734812e-01 0.325 0 0
Meiosis R-HSA-1500620 2.727569e-01 0.564 0 0
Acyl chain remodelling of PS R-HSA-1482801 4.143636e-01 0.383 0 0
PLC beta mediated events R-HSA-112043 4.202429e-01 0.376 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 4.341712e-01 0.362 0 0
DAG and IP3 signaling R-HSA-1489509 3.709563e-01 0.431 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 2.019977e-01 0.695 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 4.103802e-01 0.387 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 4.103802e-01 0.387 0 0
Toxicity of botulinum toxin type E (botE) R-HSA-5250992 4.532503e-01 0.344 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 4.930059e-01 0.307 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 4.930059e-01 0.307 0 0
Diseases of mitotic cell cycle R-HSA-9675126 3.230027e-01 0.491 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 4.197926e-01 0.377 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.090976e-01 0.510 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.995164e-01 0.398 0 0
Stabilization of p53 R-HSA-69541 4.571954e-01 0.340 0 0
Heme signaling R-HSA-9707616 4.334351e-01 0.363 0 0
Toxicity of botulinum toxin type A (botA) R-HSA-5250968 5.957650e-01 0.225 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.695322e-01 0.244 0 0
Regulation of gene expression in beta cells R-HSA-210745 2.728191e-01 0.564 0 0
Adipogenesis R-HSA-9843745 5.515701e-01 0.258 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 3.129623e-01 0.505 0 0
Selective autophagy R-HSA-9663891 3.130417e-01 0.504 1 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 3.752256e-01 0.426 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 5.666454e-01 0.247 0 0
ER to Golgi Anterograde Transport R-HSA-199977 4.755691e-01 0.323 0 0
DNA Replication Pre-Initiation R-HSA-69002 3.090976e-01 0.510 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 4.151648e-01 0.382 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 5.977356e-01 0.223 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 2.894264e-01 0.538 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 5.957650e-01 0.225 0 0
Chromosome Maintenance R-HSA-73886 4.403135e-01 0.356 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 5.405605e-01 0.267 0 0
Signal transduction by L1 R-HSA-445144 5.625405e-01 0.250 1 1
Nuclear Envelope (NE) Reassembly R-HSA-2995410 4.956305e-01 0.305 0 0
p75NTR signals via NF-kB R-HSA-193639 4.197926e-01 0.377 0 0
Cilium Assembly R-HSA-5617833 3.185495e-01 0.497 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 3.143017e-01 0.503 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 3.641516e-01 0.439 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 2.125707e-01 0.672 0 0
Cam-PDE 1 activation R-HSA-111957 4.532503e-01 0.344 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 2.004887e-01 0.698 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 3.936983e-01 0.405 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 2.005173e-01 0.698 0 0
mTORC1-mediated signalling R-HSA-166208 3.538096e-01 0.451 0 0
Viral Messenger RNA Synthesis R-HSA-168325 2.682832e-01 0.571 0 0
Orc1 removal from chromatin R-HSA-68949 3.015554e-01 0.521 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 3.568217e-01 0.448 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 3.943393e-01 0.404 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 5.298729e-01 0.276 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 5.298729e-01 0.276 0 0
Disinhibition of SNARE formation R-HSA-114516 5.298729e-01 0.276 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.729912e-01 0.325 0 0
Apoptotic factor-mediated response R-HSA-111471 5.178259e-01 0.286 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 5.178259e-01 0.286 0 0
PKA activation in glucagon signalling R-HSA-164378 5.178259e-01 0.286 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 5.405605e-01 0.267 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 4.407359e-01 0.356 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 5.015608e-01 0.300 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 5.837553e-01 0.234 0 0
G-protein mediated events R-HSA-112040 4.983591e-01 0.302 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 4.341712e-01 0.362 0 0
eNOS activation R-HSA-203615 5.977356e-01 0.223 0 0
Polo-like kinase mediated events R-HSA-156711 5.178259e-01 0.286 0 0
Extension of Telomeres R-HSA-180786 5.695322e-01 0.244 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.976047e-01 0.526 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 4.407427e-01 0.356 0 0
Assembly of the pre-replicative complex R-HSA-68867 3.754943e-01 0.425 0 0
Mitophagy R-HSA-5205647 5.977356e-01 0.223 1 0
Regulation of CDH11 gene transcription R-HSA-9762293 2.294890e-01 0.639 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.408695e-01 0.618 0 0
Neurofascin interactions R-HSA-447043 4.930059e-01 0.307 0 0
TCF dependent signaling in response to WNT R-HSA-201681 3.587479e-01 0.445 1 0
G2/M Transition R-HSA-69275 2.137890e-01 0.670 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 3.741395e-01 0.427 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 2.629295e-01 0.580 0 0
Membrane Trafficking R-HSA-199991 5.472955e-01 0.262 0 0
Mitotic G2-G2/M phases R-HSA-453274 2.255647e-01 0.647 0 0
DNA Replication R-HSA-69306 5.266435e-01 0.278 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 5.105467e-01 0.292 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 2.849602e-01 0.545 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 2.547936e-01 0.594 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 4.197926e-01 0.377 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 4.103802e-01 0.387 0 0
Lagging Strand Synthesis R-HSA-69186 5.837553e-01 0.234 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 2.831862e-01 0.548 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 2.831862e-01 0.548 0 0
Kinesins R-HSA-983189 4.070120e-01 0.390 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.919405e-01 0.308 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 5.811283e-01 0.236 1 1
Oxidative Stress Induced Senescence R-HSA-2559580 3.501941e-01 0.456 0 0
TGFBR3 PTM regulation R-HSA-9839383 2.019977e-01 0.695 0 0
2-LTR circle formation R-HSA-164843 2.572023e-01 0.590 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 2.125707e-01 0.672 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 3.126100e-01 0.505 0 0
Metalloprotease DUBs R-HSA-5689901 4.341712e-01 0.362 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 4.943535e-01 0.306 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 5.105467e-01 0.292 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 5.640930e-01 0.249 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 5.837553e-01 0.234 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.943393e-01 0.404 0 0
Calnexin/calreticulin cycle R-HSA-901042 3.737377e-01 0.427 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 2.927205e-01 0.534 1 1
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.200627e-01 0.657 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 4.943535e-01 0.306 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.282819e-01 0.368 0 0
Mismatch Repair R-HSA-5358508 5.178259e-01 0.286 0 0
TCR signaling R-HSA-202403 5.716382e-01 0.243 0 0
Signaling by Nuclear Receptors R-HSA-9006931 2.436961e-01 0.613 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 2.294890e-01 0.639 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 3.333992e-01 0.477 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 4.930059e-01 0.307 0 0
NRAGE signals death through JNK R-HSA-193648 2.129232e-01 0.672 0 0
tRNA processing in the nucleus R-HSA-6784531 2.798057e-01 0.553 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 3.906163e-01 0.408 0 0
Triglyceride biosynthesis R-HSA-75109 4.537249e-01 0.343 0 0
Early Phase of HIV Life Cycle R-HSA-162594 3.129623e-01 0.505 0 0
Ephrin signaling R-HSA-3928664 2.520968e-01 0.598 0 0
PERK regulates gene expression R-HSA-381042 3.906163e-01 0.408 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.520968e-01 0.598 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.419513e-01 0.266 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 3.995164e-01 0.398 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 2.572023e-01 0.590 0 0
NrCAM interactions R-HSA-447038 4.103802e-01 0.387 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 4.103802e-01 0.387 0 0
TGFBR3 expression R-HSA-9839394 2.084980e-01 0.681 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 4.197926e-01 0.377 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 2.976047e-01 0.526 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 5.298729e-01 0.276 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 5.640611e-01 0.249 0 0
Sodium/Proton exchangers R-HSA-425986 5.640611e-01 0.249 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 4.038284e-01 0.394 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 5.957650e-01 0.225 0 0
Trafficking of AMPA receptors R-HSA-399719 5.287868e-01 0.277 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 5.360670e-01 0.271 0 0
Protein-protein interactions at synapses R-HSA-6794362 5.532591e-01 0.257 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.341712e-01 0.362 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 4.919405e-01 0.308 0 0
Apoptosis R-HSA-109581 4.909504e-01 0.309 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.895794e-01 0.310 0 0
MHC class II antigen presentation R-HSA-2132295 5.841362e-01 0.233 0 0
G1/S Transition R-HSA-69206 2.639396e-01 0.578 0 0
Neurodegenerative Diseases R-HSA-8863678 3.943393e-01 0.404 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 3.943393e-01 0.404 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 3.230027e-01 0.491 0 0
Activation of SMO R-HSA-5635838 4.452997e-01 0.351 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 5.957650e-01 0.225 0 0
Influenza Infection R-HSA-168255 2.449566e-01 0.611 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 3.121387e-01 0.506 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 3.709563e-01 0.431 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.894264e-01 0.538 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 3.538096e-01 0.451 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 4.537249e-01 0.343 0 0
Diseases of DNA repair R-HSA-9675135 3.857185e-01 0.414 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 2.294890e-01 0.639 0 0
Regulated proteolysis of p75NTR R-HSA-193692 2.294890e-01 0.639 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 2.294890e-01 0.639 0 0
LGI-ADAM interactions R-HSA-5682910 2.849602e-01 0.545 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 4.532503e-01 0.344 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 4.532503e-01 0.344 0 0
Nef and signal transduction R-HSA-164944 4.930059e-01 0.307 0 0
Formation of the anterior neural plate R-HSA-9823739 4.197926e-01 0.377 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 4.197926e-01 0.377 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 2.400113e-01 0.620 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 5.105467e-01 0.292 0 0
G alpha (12/13) signalling events R-HSA-416482 4.719264e-01 0.326 0 0
Protein hydroxylation R-HSA-9629569 5.625405e-01 0.250 0 0
Co-inhibition by CTLA4 R-HSA-389513 5.625405e-01 0.250 0 0
Basigin interactions R-HSA-210991 5.837553e-01 0.234 0 0
Signaling by NOTCH4 R-HSA-9013694 5.843482e-01 0.233 0 0
Interleukin-7 signaling R-HSA-1266695 4.143636e-01 0.383 0 0
Signaling by ERBB4 R-HSA-1236394 5.843482e-01 0.233 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 2.401572e-01 0.620 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 5.811283e-01 0.236 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 3.539892e-01 0.451 0 0
MTOR signalling R-HSA-165159 5.211383e-01 0.283 0 0
Cellular response to mitochondrial stress R-HSA-9840373 2.294890e-01 0.639 0 0
Regulation of gene expression in early pancreatic precursor cells R-HSA-210747 2.849602e-01 0.545 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 5.640611e-01 0.249 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 5.178259e-01 0.286 0 0
STING mediated induction of host immune responses R-HSA-1834941 5.405605e-01 0.267 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 4.282819e-01 0.368 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 3.126100e-01 0.505 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.537249e-01 0.343 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 5.640611e-01 0.249 0 0
Maturation of nucleoprotein R-HSA-9694631 5.405605e-01 0.267 0 0
Signaling by TGFB family members R-HSA-9006936 2.748348e-01 0.561 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 5.298729e-01 0.276 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 4.241455e-01 0.372 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 5.105467e-01 0.292 0 0
Signaling by FGFR in disease R-HSA-1226099 2.818539e-01 0.550 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 4.452997e-01 0.351 0 0
Nephron development R-HSA-9831926 5.178259e-01 0.286 0 0
Other interleukin signaling R-HSA-449836 5.405605e-01 0.267 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 5.640930e-01 0.249 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 3.670816e-01 0.435 0 0
IRE1alpha activates chaperones R-HSA-381070 2.370505e-01 0.625 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 4.943535e-01 0.306 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 5.977356e-01 0.223 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 4.726462e-01 0.325 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 3.936983e-01 0.405 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 5.405605e-01 0.267 0 0
Interleukin-12 family signaling R-HSA-447115 5.864201e-01 0.232 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 5.977356e-01 0.223 0 0
Regulation of TNFR1 signaling R-HSA-5357905 5.812735e-01 0.236 0 0
Virus Assembly and Release R-HSA-168268 4.452997e-01 0.351 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 4.571954e-01 0.340 1 0
ABC-family proteins mediated transport R-HSA-382556 5.986985e-01 0.223 0 0
Signaling by PDGFR in disease R-HSA-9671555 6.042001e-01 0.219 0 0
Interleukin-12 signaling R-HSA-9020591 6.074962e-01 0.216 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 6.079197e-01 0.216 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 6.079197e-01 0.216 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 6.079197e-01 0.216 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 6.079197e-01 0.216 0 0
Regulation of Apoptosis R-HSA-169911 6.139059e-01 0.212 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 6.139059e-01 0.212 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.184592e-01 0.209 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 6.202677e-01 0.207 0 0
Degradation of CDH1 R-HSA-9766229 6.233958e-01 0.205 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 6.233958e-01 0.205 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 6.233958e-01 0.205 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 6.233958e-01 0.205 0 0
FGFR2 alternative splicing R-HSA-6803529 6.238746e-01 0.205 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 6.238746e-01 0.205 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 6.238746e-01 0.205 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 6.251650e-01 0.204 0 0
Receptor Mediated Mitophagy R-HSA-8934903 6.251650e-01 0.204 1 1
DNA replication initiation R-HSA-68952 6.251650e-01 0.204 0 0
Regulation of CDH11 function R-HSA-9762292 6.251650e-01 0.204 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 6.251650e-01 0.204 0 0
Pexophagy R-HSA-9664873 6.251650e-01 0.204 0 0
CASP4 inflammasome assembly R-HSA-9948001 6.251650e-01 0.204 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 6.251650e-01 0.204 0 0
Regulation of the apoptosome activity R-HSA-9627069 6.251650e-01 0.204 0 0
Interleukin-27 signaling R-HSA-9020956 6.251650e-01 0.204 0 0
Maturation of spike protein R-HSA-9683686 6.251650e-01 0.204 0 0
Formation of apoptosome R-HSA-111458 6.251650e-01 0.204 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 6.251650e-01 0.204 0 0
Programmed Cell Death R-HSA-5357801 6.276931e-01 0.202 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 6.286462e-01 0.202 0 0
PRC2 methylates histones and DNA R-HSA-212300 6.296322e-01 0.201 0 0
FLT3 signaling in disease R-HSA-9682385 6.296322e-01 0.201 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 6.371884e-01 0.196 0 0
Opioid Signalling R-HSA-111885 6.376923e-01 0.195 0 0
Response of endothelial cells to shear stress R-HSA-9860931 6.376923e-01 0.195 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 6.427827e-01 0.192 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 6.427827e-01 0.192 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.427827e-01 0.192 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 6.427827e-01 0.192 0 0
Cellular response to hypoxia R-HSA-1234174 6.442568e-01 0.191 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 6.449098e-01 0.191 0 0
Macroautophagy R-HSA-1632852 6.454816e-01 0.190 1 0
L1CAM interactions R-HSA-373760 6.460942e-01 0.190 1 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 6.524283e-01 0.185 0 0
Signaling by APC mutants R-HSA-4839744 6.524283e-01 0.185 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 6.524283e-01 0.185 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 6.524283e-01 0.185 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 6.524283e-01 0.185 0 0
Ionotropic activity of kainate receptors R-HSA-451306 6.524283e-01 0.185 0 0
vRNP Assembly R-HSA-192905 6.524283e-01 0.185 0 0
Synthesis of PI R-HSA-1483226 6.524283e-01 0.185 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 6.524283e-01 0.185 0 0
Bicarbonate transporters R-HSA-425381 6.524283e-01 0.185 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 6.524283e-01 0.185 0 0
Suppression of apoptosis R-HSA-9635465 6.524283e-01 0.185 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 6.524283e-01 0.185 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 6.533246e-01 0.185 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 6.597358e-01 0.181 0 0
Autophagy R-HSA-9612973 6.609071e-01 0.180 1 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 6.609319e-01 0.180 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 6.609319e-01 0.180 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 6.609319e-01 0.180 0 0
Complex III assembly R-HSA-9865881 6.609319e-01 0.180 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 6.609319e-01 0.180 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 6.613752e-01 0.180 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 6.627333e-01 0.179 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 6.627333e-01 0.179 0 0
Muscle contraction R-HSA-397014 6.744102e-01 0.171 0 0
Gene Silencing by RNA R-HSA-211000 6.744737e-01 0.171 0 0
Signaling by NOTCH R-HSA-157118 6.748091e-01 0.171 0 0
Signaling by GSK3beta mutants R-HSA-5339716 6.777102e-01 0.169 0 0
Proton-coupled monocarboxylate transport R-HSA-433692 6.777102e-01 0.169 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 6.777102e-01 0.169 0 0
ERKs are inactivated R-HSA-202670 6.777102e-01 0.169 0 0
Signaling by AXIN mutants R-HSA-4839735 6.777102e-01 0.169 0 0
Signaling by AMER1 mutants R-HSA-4839748 6.777102e-01 0.169 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 6.777102e-01 0.169 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 6.777102e-01 0.169 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 6.777102e-01 0.169 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 6.777102e-01 0.169 0 0
Sodium/Calcium exchangers R-HSA-425561 6.777102e-01 0.169 0 0
Activation of RAC1 R-HSA-428540 6.777102e-01 0.169 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 6.777102e-01 0.169 0 0
Tight junction interactions R-HSA-420029 6.783323e-01 0.169 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 6.783323e-01 0.169 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 6.784099e-01 0.169 0 0
Signaling by WNT R-HSA-195721 6.877544e-01 0.163 1 0
Regulation of RUNX3 expression and activity R-HSA-8941858 6.880292e-01 0.162 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 6.880292e-01 0.162 0 0
Signaling by EGFR in Cancer R-HSA-1643713 6.949970e-01 0.158 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 6.949970e-01 0.158 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 6.949970e-01 0.158 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 6.949970e-01 0.158 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 6.949970e-01 0.158 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 6.963298e-01 0.157 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.007257e-01 0.154 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 7.011545e-01 0.154 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 7.011545e-01 0.154 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 7.011545e-01 0.154 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 7.011545e-01 0.154 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 7.011545e-01 0.154 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 7.011545e-01 0.154 0 0
Polymerase switching R-HSA-69091 7.011545e-01 0.154 0 0
Leading Strand Synthesis R-HSA-69109 7.011545e-01 0.154 0 0
p75NTR recruits signalling complexes R-HSA-209543 7.011545e-01 0.154 0 0
Regulation of IFNG signaling R-HSA-877312 7.011545e-01 0.154 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 7.011545e-01 0.154 0 0
Interleukin-35 Signalling R-HSA-8984722 7.011545e-01 0.154 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 7.014987e-01 0.154 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 7.014987e-01 0.154 0 0
Telomere Maintenance R-HSA-157579 7.053091e-01 0.152 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 7.103012e-01 0.149 0 0
Regulation of mitotic cell cycle R-HSA-453276 7.103012e-01 0.149 0 0
Hedgehog 'on' state R-HSA-5632684 7.103012e-01 0.149 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.106787e-01 0.148 0 0
TNF signaling R-HSA-75893 7.106787e-01 0.148 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.109408e-01 0.148 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 7.109408e-01 0.148 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.109408e-01 0.148 0 0
Synthesis of PE R-HSA-1483213 7.109408e-01 0.148 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 7.109408e-01 0.148 0 0
Gastrulation R-HSA-9758941 7.137064e-01 0.146 0 0
Post-translational protein phosphorylation R-HSA-8957275 7.141110e-01 0.146 0 0
MAP2K and MAPK activation R-HSA-5674135 7.145203e-01 0.146 0 0
Scavenging by Class A Receptors R-HSA-3000480 7.145203e-01 0.146 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 7.166992e-01 0.145 0 0
Regulation of CDH1 Function R-HSA-9764561 7.218533e-01 0.142 0 0
Nervous system development R-HSA-9675108 7.221131e-01 0.141 1 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 7.228947e-01 0.141 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 7.228947e-01 0.141 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 7.228947e-01 0.141 0 0
CD28 dependent Vav1 pathway R-HSA-389359 7.228947e-01 0.141 0 0
Maturation of nucleoprotein R-HSA-9683610 7.228947e-01 0.141 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 7.228947e-01 0.141 0 0
SARS-CoV Infections R-HSA-9679506 7.246405e-01 0.140 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.261805e-01 0.139 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 7.261805e-01 0.139 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 7.261805e-01 0.139 0 0
Signaling by VEGF R-HSA-194138 7.280332e-01 0.138 0 0
Organelle biogenesis and maintenance R-HSA-1852241 7.290278e-01 0.137 0 0
Chaperonin-mediated protein folding R-HSA-390466 7.300857e-01 0.137 1 0
Ca2+ pathway R-HSA-4086398 7.302891e-01 0.137 0 0
Ribosome-associated quality control R-HSA-9948299 7.311752e-01 0.136 0 0
Hedgehog 'off' state R-HSA-5610787 7.311786e-01 0.136 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 7.330738e-01 0.135 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 7.344887e-01 0.134 0 0
Diseases of programmed cell death R-HSA-9645723 7.389596e-01 0.131 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 7.392373e-01 0.131 0 0
Defective pyroptosis R-HSA-9710421 7.392373e-01 0.131 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 7.392373e-01 0.131 0 0
Axon guidance R-HSA-422475 7.393493e-01 0.131 1 0
Late endosomal microautophagy R-HSA-9615710 7.407340e-01 0.130 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.407340e-01 0.130 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 7.407340e-01 0.130 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 7.430546e-01 0.129 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 7.430546e-01 0.129 0 0
Hydrolysis of LPC R-HSA-1483115 7.430546e-01 0.129 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 7.430546e-01 0.129 0 0
Non-canonical inflammasome activation R-HSA-9686114 7.430546e-01 0.129 0 0
Signal regulatory protein family interactions R-HSA-391160 7.430546e-01 0.129 0 0
Acyl chain remodeling of CL R-HSA-1482798 7.430546e-01 0.129 0 0
Regulation of beta-cell development R-HSA-186712 7.432349e-01 0.129 0 0
Viral Infection Pathways R-HSA-9824446 7.497359e-01 0.125 1 0
Proteasome assembly R-HSA-9907900 7.509440e-01 0.124 0 0
EPHB-mediated forward signaling R-HSA-3928662 7.509440e-01 0.124 0 0
Signaling by ERBB2 R-HSA-1227986 7.534463e-01 0.123 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 7.534463e-01 0.123 0 0
Activation of BH3-only proteins R-HSA-114452 7.546206e-01 0.122 0 0
UCH proteinases R-HSA-5689603 7.583652e-01 0.120 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 7.617489e-01 0.118 0 0
Translesion synthesis by REV1 R-HSA-110312 7.617489e-01 0.118 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 7.617489e-01 0.118 0 0
Processive synthesis on the lagging strand R-HSA-69183 7.617489e-01 0.118 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 7.617489e-01 0.118 0 0
Cell-extracellular matrix interactions R-HSA-446353 7.617489e-01 0.118 0 0
DCC mediated attractive signaling R-HSA-418885 7.617489e-01 0.118 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 7.622249e-01 0.118 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 7.622249e-01 0.118 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 7.622249e-01 0.118 0 0
Interferon Signaling R-HSA-913531 7.633379e-01 0.117 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 7.677821e-01 0.115 0 0
Budding and maturation of HIV virion R-HSA-162588 7.678601e-01 0.115 0 0
Cargo concentration in the ER R-HSA-5694530 7.678601e-01 0.115 0 0
Reproduction R-HSA-1474165 7.706429e-01 0.113 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 7.723583e-01 0.112 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 7.729257e-01 0.112 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 7.746849e-01 0.111 0 0
PCP/CE pathway R-HSA-4086400 7.758271e-01 0.110 0 0
Translesion synthesis by POLI R-HSA-5656121 7.790842e-01 0.108 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 7.790842e-01 0.108 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 7.790842e-01 0.108 0 0
Prolonged ERK activation events R-HSA-169893 7.790842e-01 0.108 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 7.790842e-01 0.108 0 0
Atorvastatin ADME R-HSA-9754706 7.790842e-01 0.108 0 0
Eukaryotic Translation Elongation R-HSA-156842 7.801884e-01 0.108 0 0
Protein folding R-HSA-391251 7.801884e-01 0.108 1 0
Signaling by WNT in cancer R-HSA-4791275 7.804733e-01 0.108 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.804733e-01 0.108 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 7.804733e-01 0.108 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 7.822013e-01 0.107 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 7.835404e-01 0.106 0 0
Synthesis of PC R-HSA-1483191 7.835404e-01 0.106 1 1
Signaling by ROBO receptors R-HSA-376176 7.840143e-01 0.106 0 0
Generic Transcription Pathway R-HSA-212436 7.841216e-01 0.106 1 0
Sensory processing of sound R-HSA-9659379 7.841875e-01 0.106 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 7.841875e-01 0.106 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 7.923043e-01 0.101 0 0
Integrin signaling R-HSA-354192 7.924811e-01 0.101 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 7.924811e-01 0.101 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.924811e-01 0.101 0 0
Cardiogenesis R-HSA-9733709 7.924811e-01 0.101 0 0
G-protein beta:gamma signalling R-HSA-397795 7.924811e-01 0.101 0 0
NGF-stimulated transcription R-HSA-9031628 7.935917e-01 0.100 0 0
Co-stimulation by CD28 R-HSA-389356 7.935917e-01 0.100 0 0
GPER1 signaling R-HSA-9634597 7.935917e-01 0.100 0 0
Translesion synthesis by POLK R-HSA-5655862 7.951590e-01 0.100 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 7.951590e-01 0.100 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 7.951590e-01 0.100 0 0
Fibronectin matrix formation R-HSA-1566977 7.951590e-01 0.100 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 7.951590e-01 0.100 0 0
Synthesis of PG R-HSA-1483148 7.951590e-01 0.100 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 7.951590e-01 0.100 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 8.001804e-01 0.097 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 8.032999e-01 0.095 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.039048e-01 0.095 0 0
Vpu mediated degradation of CD4 R-HSA-180534 8.039048e-01 0.095 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 8.039048e-01 0.095 0 0
Eukaryotic Translation Termination R-HSA-72764 8.094774e-01 0.092 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 8.100651e-01 0.091 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 8.100651e-01 0.091 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 8.100651e-01 0.091 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 8.100651e-01 0.091 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 8.100651e-01 0.091 0 0
Uptake and function of anthrax toxins R-HSA-5210891 8.100651e-01 0.091 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 8.147659e-01 0.089 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 8.147659e-01 0.089 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 8.147659e-01 0.089 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 8.163023e-01 0.088 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 8.214302e-01 0.085 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 8.214302e-01 0.085 0 0
Hedgehog ligand biogenesis R-HSA-5358346 8.214302e-01 0.085 0 0
HCMV Early Events R-HSA-9609690 8.229333e-01 0.085 0 0
Transport of connexons to the plasma membrane R-HSA-190872 8.238874e-01 0.084 0 0
Platelet sensitization by LDL R-HSA-432142 8.238874e-01 0.084 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 8.238874e-01 0.084 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.250856e-01 0.084 0 0
Oncogene Induced Senescence R-HSA-2559585 8.250856e-01 0.084 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 8.250856e-01 0.084 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 8.250856e-01 0.084 0 0
Signaling by Hedgehog R-HSA-5358351 8.252486e-01 0.083 0 0
Translation R-HSA-72766 8.282806e-01 0.082 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 8.299702e-01 0.081 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 8.316577e-01 0.080 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 8.348853e-01 0.078 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.348853e-01 0.078 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 8.360707e-01 0.078 0 0
Translesion Synthesis by POLH R-HSA-110320 8.367044e-01 0.077 0 0
Germ layer formation at gastrulation R-HSA-9754189 8.367044e-01 0.077 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 8.367044e-01 0.077 0 0
The NLRP3 inflammasome R-HSA-844456 8.367044e-01 0.077 0 0
SARS-CoV-2-host interactions R-HSA-9705683 8.369166e-01 0.077 0 0
Amino acids regulate mTORC1 R-HSA-9639288 8.381573e-01 0.077 0 0
COPII-mediated vesicle transport R-HSA-204005 8.389189e-01 0.076 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 8.389189e-01 0.076 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 8.423010e-01 0.075 0 0
Degradation of DVL R-HSA-4641258 8.441859e-01 0.074 0 0
Degradation of AXIN R-HSA-4641257 8.441859e-01 0.074 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 8.441859e-01 0.074 0 0
Metabolism of folate and pterines R-HSA-196757 8.441859e-01 0.074 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 8.475716e-01 0.072 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 8.485894e-01 0.071 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 8.485894e-01 0.071 0 0
Negative regulation of MET activity R-HSA-6807004 8.485894e-01 0.071 0 0
Acyl chain remodelling of PI R-HSA-1482922 8.485894e-01 0.071 0 0
Formation of definitive endoderm R-HSA-9823730 8.485894e-01 0.071 0 0
Pregnenolone biosynthesis R-HSA-196108 8.485894e-01 0.071 0 0
Nephrin family interactions R-HSA-373753 8.485894e-01 0.071 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 8.495896e-01 0.071 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 8.526541e-01 0.069 0 0
Elastic fibre formation R-HSA-1566948 8.530081e-01 0.069 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.530081e-01 0.069 0 0
Post-translational protein modification R-HSA-597592 8.550648e-01 0.068 0 0
ERK/MAPK targets R-HSA-198753 8.596101e-01 0.066 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 8.596101e-01 0.066 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 8.596101e-01 0.066 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 8.596101e-01 0.066 0 0
Acyl chain remodelling of PG R-HSA-1482925 8.596101e-01 0.066 0 0
Ion homeostasis R-HSA-5578775 8.607036e-01 0.065 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 8.607036e-01 0.065 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 8.613724e-01 0.065 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 8.613724e-01 0.065 0 0
Rab regulation of trafficking R-HSA-9007101 8.634306e-01 0.064 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 8.641570e-01 0.063 0 0
Base Excision Repair R-HSA-73884 8.665052e-01 0.062 0 0
Downstream TCR signaling R-HSA-202424 8.665052e-01 0.062 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 8.683352e-01 0.061 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 8.692985e-01 0.061 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.692985e-01 0.061 0 0
Diseases of Immune System R-HSA-5260271 8.692985e-01 0.061 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.693422e-01 0.061 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.693422e-01 0.061 0 0
Serine metabolism R-HSA-977347 8.698292e-01 0.061 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 8.719850e-01 0.059 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 8.768059e-01 0.057 0 0
Maturation of spike protein R-HSA-9694548 8.768059e-01 0.057 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 8.768059e-01 0.057 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 8.768059e-01 0.057 0 0
SARS-CoV-1-host interactions R-HSA-9692914 8.792185e-01 0.056 0 0
Cellular hexose transport R-HSA-189200 8.793050e-01 0.056 0 0
Peroxisomal protein import R-HSA-9033241 8.804447e-01 0.055 0 0
Triglyceride metabolism R-HSA-8979227 8.804447e-01 0.055 0 0
Translation of Structural Proteins R-HSA-9694635 8.827008e-01 0.054 0 0
Degradation of CRY and PER proteins R-HSA-9932298 8.839136e-01 0.054 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 8.839136e-01 0.054 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.839136e-01 0.054 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 8.839136e-01 0.054 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 8.839136e-01 0.054 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 8.839136e-01 0.054 0 0
Translation of Structural Proteins R-HSA-9683701 8.839136e-01 0.054 0 0
ABC transporter disorders R-HSA-5619084 8.880267e-01 0.052 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 8.880916e-01 0.052 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 8.880916e-01 0.052 0 0
Interleukin receptor SHC signaling R-HSA-912526 8.880916e-01 0.052 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.906400e-01 0.050 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 8.907263e-01 0.050 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 8.936396e-01 0.049 1 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 8.962389e-01 0.048 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 8.962389e-01 0.048 0 0
Mitochondrial RNA degradation R-HSA-9836573 8.962389e-01 0.048 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 8.962389e-01 0.048 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 8.966019e-01 0.047 0 0
TBC/RABGAPs R-HSA-8854214 8.970028e-01 0.047 0 0
Co-inhibition by PD-1 R-HSA-389948 8.985104e-01 0.046 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.030194e-01 0.044 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 9.037936e-01 0.044 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.037936e-01 0.044 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.037936e-01 0.044 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 9.037936e-01 0.044 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 9.037936e-01 0.044 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.052379e-01 0.043 0 0
Vesicle-mediated transport R-HSA-5653656 9.066032e-01 0.043 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.080962e-01 0.042 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 9.087064e-01 0.042 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.087064e-01 0.042 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 9.087064e-01 0.042 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.087064e-01 0.042 0 0
Somitogenesis R-HSA-9824272 9.087064e-01 0.042 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 9.107987e-01 0.041 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.115974e-01 0.040 0 0
Cellular response to starvation R-HSA-9711097 9.135388e-01 0.039 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.140799e-01 0.039 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 9.172940e-01 0.037 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 9.172940e-01 0.037 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 9.172940e-01 0.037 0 0
Insulin processing R-HSA-264876 9.172940e-01 0.037 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.172940e-01 0.037 1 1
SARS-CoV-1 Infection R-HSA-9678108 9.187926e-01 0.037 0 0
Recycling pathway of L1 R-HSA-437239 9.191554e-01 0.037 0 0
Glycolysis R-HSA-70171 9.206380e-01 0.036 0 0
Insulin receptor recycling R-HSA-77387 9.233168e-01 0.035 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 9.233168e-01 0.035 0 0
Inflammasomes R-HSA-622312 9.233168e-01 0.035 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.235201e-01 0.035 0 0
Metal ion SLC transporters R-HSA-425410 9.239477e-01 0.034 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.250864e-01 0.034 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.255735e-01 0.034 0 0
PI Metabolism R-HSA-1483255 9.274746e-01 0.033 0 0
DNA Damage Bypass R-HSA-73893 9.284712e-01 0.032 0 0
Gap junction trafficking and regulation R-HSA-157858 9.284712e-01 0.032 0 0
DNA methylation R-HSA-5334118 9.289013e-01 0.032 0 0
Platelet calcium homeostasis R-HSA-418360 9.289013e-01 0.032 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 9.289013e-01 0.032 0 0
Regulation of RAS by GAPs R-HSA-5658442 9.327395e-01 0.030 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.327395e-01 0.030 0 0
Peptide chain elongation R-HSA-156902 9.339774e-01 0.030 0 0
DAP12 signaling R-HSA-2424491 9.340794e-01 0.030 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.340794e-01 0.030 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 9.350032e-01 0.029 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 9.366992e-01 0.028 0 0
Metabolism of cofactors R-HSA-8978934 9.366992e-01 0.028 0 0
Meiotic recombination R-HSA-912446 9.367660e-01 0.028 0 0
The phototransduction cascade R-HSA-2514856 9.367660e-01 0.028 0 0
ER-Phagosome pathway R-HSA-1236974 9.371642e-01 0.028 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 9.388807e-01 0.027 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.388807e-01 0.027 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 9.388807e-01 0.027 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.388807e-01 0.027 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 9.388807e-01 0.027 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 9.388807e-01 0.027 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 9.395122e-01 0.027 1 1
Nuclear events mediated by NFE2L2 R-HSA-9759194 9.403805e-01 0.027 0 0
HCMV Infection R-HSA-9609646 9.447919e-01 0.025 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.485596e-01 0.023 0 0
Iron uptake and transport R-HSA-917937 9.491798e-01 0.023 0 0
Signaling by NOTCH3 R-HSA-9012852 9.506957e-01 0.022 0 0
Miscellaneous transport and binding events R-HSA-5223345 9.512878e-01 0.022 0 0
Effects of PIP2 hydrolysis R-HSA-114508 9.512878e-01 0.022 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 9.512878e-01 0.022 0 0
Heme degradation R-HSA-189483 9.512878e-01 0.022 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 9.521264e-01 0.021 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 9.521264e-01 0.021 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 9.521264e-01 0.021 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.548366e-01 0.020 1 1
Gap junction assembly R-HSA-190861 9.548366e-01 0.020 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.548366e-01 0.020 0 0
Signal amplification R-HSA-392518 9.548366e-01 0.020 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 9.558269e-01 0.020 0 0
Synthesis of PA R-HSA-1483166 9.565106e-01 0.019 0 0
Signalling to ERKs R-HSA-187687 9.581270e-01 0.019 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.581270e-01 0.019 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.591660e-01 0.018 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.591660e-01 0.018 0 0
RET signaling R-HSA-8853659 9.611779e-01 0.017 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 9.611779e-01 0.017 0 0
GPVI-mediated activation cascade R-HSA-114604 9.611779e-01 0.017 0 0
G1/S-Specific Transcription R-HSA-69205 9.611779e-01 0.017 0 0
RUNX2 regulates bone development R-HSA-8941326 9.611779e-01 0.017 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.640067e-01 0.016 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.640067e-01 0.016 0 0
Metabolism of polyamines R-HSA-351202 9.640178e-01 0.016 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.640887e-01 0.016 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 9.656675e-01 0.015 0 0
FOXO-mediated transcription R-HSA-9614085 9.658666e-01 0.015 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.662310e-01 0.015 0 0
Aquaporin-mediated transport R-HSA-445717 9.662310e-01 0.015 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.662310e-01 0.015 0 0
Circadian clock R-HSA-9909396 9.666334e-01 0.015 1 0
SLC transporter disorders R-HSA-5619102 9.683608e-01 0.014 0 0
Mitochondrial biogenesis R-HSA-1592230 9.689632e-01 0.014 0 0
Glucose metabolism R-HSA-70326 9.689632e-01 0.014 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 9.690613e-01 0.014 0 0
RAS processing R-HSA-9648002 9.690613e-01 0.014 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.690613e-01 0.014 0 0
Selenocysteine synthesis R-HSA-2408557 9.692525e-01 0.014 0 0
Interleukin-1 signaling R-HSA-9020702 9.692525e-01 0.014 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 9.702709e-01 0.013 0 0
Signaling by PTK6 R-HSA-8848021 9.702709e-01 0.013 0 0
Glycogen metabolism R-HSA-8982491 9.713161e-01 0.013 0 0
Interleukin-2 family signaling R-HSA-451927 9.713161e-01 0.013 0 0
Ion transport by P-type ATPases R-HSA-936837 9.721119e-01 0.012 0 0
Viral mRNA Translation R-HSA-192823 9.723227e-01 0.012 0 0
Protein localization R-HSA-9609507 9.731762e-01 0.012 0 0
tRNA processing R-HSA-72306 9.732729e-01 0.012 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.734066e-01 0.012 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.734066e-01 0.012 0 0
FLT3 Signaling R-HSA-9607240 9.734066e-01 0.012 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 9.737479e-01 0.012 0 0
Negative regulation of MAPK pathway R-HSA-5675221 9.753450e-01 0.011 0 0
Intra-Golgi traffic R-HSA-6811438 9.753450e-01 0.011 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.753450e-01 0.011 0 0
PPARA activates gene expression R-HSA-1989781 9.754635e-01 0.011 0 0
Kidney development R-HSA-9830369 9.769982e-01 0.010 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.771421e-01 0.010 0 0
Depyrimidination R-HSA-73928 9.771421e-01 0.010 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.771421e-01 0.010 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 9.771421e-01 0.010 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.774790e-01 0.010 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.775701e-01 0.010 0 0
Parasite infection R-HSA-9664407 9.780690e-01 0.010 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.780690e-01 0.010 0 0
Leishmania phagocytosis R-HSA-9664417 9.780690e-01 0.010 0 0
Regulated Necrosis R-HSA-5218859 9.784345e-01 0.009 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.787880e-01 0.009 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 9.788083e-01 0.009 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.788083e-01 0.009 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 9.794839e-01 0.009 0 0
Neurotransmitter release cycle R-HSA-112310 9.795340e-01 0.009 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.798973e-01 0.009 0 0
DAP12 interactions R-HSA-2172127 9.803532e-01 0.009 0 0
Gap junction trafficking R-HSA-190828 9.803532e-01 0.009 0 0
Methylation R-HSA-156581 9.803532e-01 0.009 0 0
Cyclin D associated events in G1 R-HSA-69231 9.803532e-01 0.009 0 0
G1 Phase R-HSA-69236 9.803532e-01 0.009 0 0
Netrin-1 signaling R-HSA-373752 9.803532e-01 0.009 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 9.805948e-01 0.009 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 9.806931e-01 0.008 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.808502e-01 0.008 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.810511e-01 0.008 0 0
Clathrin-mediated endocytosis R-HSA-8856828 9.818782e-01 0.008 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 9.822411e-01 0.008 0 0
Signal Transduction R-HSA-162582 9.829193e-01 0.007 1 0
Signaling by NTRK1 (TRKA) R-HSA-187037 9.829519e-01 0.007 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.831135e-01 0.007 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.831135e-01 0.007 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 9.843448e-01 0.007 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.843448e-01 0.007 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.843448e-01 0.007 0 0
Aspirin ADME R-HSA-9749641 9.844073e-01 0.007 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 9.846071e-01 0.007 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 9.846688e-01 0.007 0 0
Signaling by NTRKs R-HSA-166520 9.857727e-01 0.006 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.859825e-01 0.006 1 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.863158e-01 0.006 0 0
Neddylation R-HSA-8951664 9.865992e-01 0.006 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.874737e-01 0.005 0 0
Azathioprine ADME R-HSA-9748787 9.875259e-01 0.005 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.875259e-01 0.005 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.879960e-01 0.005 0 0
Phospholipid metabolism R-HSA-1483257 9.885952e-01 0.005 1 0
Regulation of insulin secretion R-HSA-422356 9.886515e-01 0.005 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.887590e-01 0.005 0 0
MAPK family signaling cascades R-HSA-5683057 9.890063e-01 0.005 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.894745e-01 0.005 0 0
Signaling by FGFR2 R-HSA-5654738 9.901456e-01 0.004 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.907861e-01 0.004 0 0
HCMV Late Events R-HSA-9610379 9.908801e-01 0.004 0 0
Paracetamol ADME R-HSA-9753281 9.914582e-01 0.004 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.915928e-01 0.004 0 0
Cellular response to chemical stress R-HSA-9711123 9.916336e-01 0.004 1 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.919177e-01 0.004 0 0
Signaling by EGFR R-HSA-177929 9.920814e-01 0.003 0 0
RSV-host interactions R-HSA-9833110 9.925501e-01 0.003 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.936912e-01 0.003 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.938033e-01 0.003 0 0
Platelet degranulation R-HSA-114608 9.940614e-01 0.003 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.945784e-01 0.002 0 0
MAP kinase activation R-HSA-450294 9.945784e-01 0.002 0 0
Mitochondrial protein import R-HSA-1268020 9.949740e-01 0.002 0 0
Cardiac conduction R-HSA-5576891 9.955389e-01 0.002 0 0
IGF1R signaling cascade R-HSA-2428924 9.956809e-01 0.002 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 9.956809e-01 0.002 0 0
Neutrophil degranulation R-HSA-6798695 9.957238e-01 0.002 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.957567e-01 0.002 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.959962e-01 0.002 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.962884e-01 0.002 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.963728e-01 0.002 0 0
Metabolism of proteins R-HSA-392499 9.964625e-01 0.002 1 0
Nicotinate metabolism R-HSA-196807 9.965594e-01 0.001 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.965594e-01 0.001 0 0
Metabolism of steroid hormones R-HSA-196071 9.965594e-01 0.001 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 9.966089e-01 0.001 0 0
Mitochondrial protein degradation R-HSA-9837999 9.966089e-01 0.001 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.968106e-01 0.001 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.970544e-01 0.001 0 0
Mitochondrial translation elongation R-HSA-5389840 9.972303e-01 0.001 0 0
Interleukin-17 signaling R-HSA-448424 9.972593e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.974594e-01 0.001 0 0
Metabolism of porphyrins R-HSA-189445 9.974594e-01 0.001 0 0
Mitochondrial translation initiation R-HSA-5368286 9.975808e-01 0.001 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 9.975808e-01 0.001 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 9.975808e-01 0.001 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 9.975808e-01 0.001 0 0
Signaling by FGFR R-HSA-190236 9.975808e-01 0.001 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.976806e-01 0.001 0 0
Signaling by Interleukins R-HSA-449147 9.977014e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.977393e-01 0.001 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.979616e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.979764e-01 0.001 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.981241e-01 0.001 0 0
Adaptive Immune System R-HSA-1280218 9.981251e-01 0.001 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.981405e-01 0.001 0 0
Transmission across Chemical Synapses R-HSA-112315 9.982301e-01 0.001 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.984153e-01 0.001 0 0
RAF/MAP kinase cascade R-HSA-5673001 9.984823e-01 0.001 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.985059e-01 0.001 0 0
Integrin cell surface interactions R-HSA-216083 9.985059e-01 0.001 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 9.985958e-01 0.001 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.986151e-01 0.001 0 0
Cytokine Signaling in Immune system R-HSA-1280215 9.986527e-01 0.001 0 0
G alpha (s) signalling events R-HSA-418555 9.986549e-01 0.001 0 0
Platelet homeostasis R-HSA-418346 9.986885e-01 0.001 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.986981e-01 0.001 0 0
Signaling by MET R-HSA-6806834 9.987162e-01 0.001 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.987538e-01 0.001 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.988075e-01 0.001 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.988448e-01 0.001 0 0
Interleukin-1 family signaling R-HSA-446652 9.988448e-01 0.001 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 9.988562e-01 0.000 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 9.989020e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.989319e-01 0.000 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 9.989319e-01 0.000 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 9.990027e-01 0.000 0 0
MyD88-independent TLR4 cascade R-HSA-166166 9.990027e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.990027e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.990523e-01 0.000 0 0
Parasitic Infection Pathways R-HSA-9824443 9.991088e-01 0.000 0 0
Leishmania infection R-HSA-9658195 9.991088e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.991306e-01 0.000 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 9.991883e-01 0.000 0 0
Interferon gamma signaling R-HSA-877300 9.992420e-01 0.000 0 0
Integration of energy metabolism R-HSA-163685 9.992615e-01 0.000 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 9.993397e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.993504e-01 0.000 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.993837e-01 0.000 0 0
Interferon alpha/beta signaling R-HSA-909733 9.993837e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.994370e-01 0.000 1 0
Selenoamino acid metabolism R-HSA-2408522 9.994404e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.994632e-01 0.000 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 9.995325e-01 0.000 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 9.995325e-01 0.000 0 0
Signaling by Insulin receptor R-HSA-74752 9.995564e-01 0.000 0 0
Developmental Biology R-HSA-1266738 9.996085e-01 0.000 1 0
Collagen formation R-HSA-1474290 9.996189e-01 0.000 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 9.996202e-01 0.000 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 9.996202e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.996969e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.996969e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.998353e-01 0.000 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.998870e-01 0.000 0 0
Stimuli-sensing channels R-HSA-2672351 9.998870e-01 0.000 0 0
Toll-like Receptor Cascades R-HSA-168898 9.999013e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999100e-01 0.000 0 0
Neuronal System R-HSA-112316 9.999245e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999475e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999501e-01 0.000 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 9.999535e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999639e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999649e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999690e-01 0.000 0 0
Ion channel transport R-HSA-983712 9.999802e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999855e-01 0.000 0 0
Hemostasis R-HSA-109582 9.999868e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999903e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999949e-01 0.000 0 0
Developmental Cell Lineages R-HSA-9734767 9.999951e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999952e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999974e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999984e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999989e-01 0.000 0 0
Disease R-HSA-1643685 9.999990e-01 0.000 1 0
Bacterial Infection Pathways R-HSA-9824439 9.999992e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999997e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999998e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999998e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999999e-01 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
GPCR downstream signalling R-HSA-388396 1.000000e+00 0.000 0 0
Immune System R-HSA-168256 1.000000e+00 0.000 0 0
G alpha (q) signalling events R-HSA-416476 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.000000e+00 0.000 0 0
Innate Immune System R-HSA-168249 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 1 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 1 0
GPCR ligand binding R-HSA-500792 1.000000e+00 -0.000 0 0
WNT mediated activation of DVL R-HSA-201688 1.000000e+00 0.000 1 1
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways