CK2A1

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
O00170 S43 GPS6|SIGNOR|PSP|Sugiyama AIP XAP2 GELPDFQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELI
O00264 S181 Sugiyama PGRMC1 HPR6.6 PGRMC TFKYHHVGKLLKEGEEPtVysDEEEPKDEsARKND______
O00264 S57 Sugiyama PGRMC1 HPR6.6 PGRMC LCIFLLYKIVRGDQPAAsGDsDDDEPPPLPRLKRRDFtPAE
O00327 S90 GPS6 BMAL1 ARNTL BHLHE5 MOP3 PASD3 IKNAREAHsQIEKRRRDKMNsFIDELASLVPTCNAMSRKLD
O00505 S60 Sugiyama KPNA3 QIP2 KRDEHLLKKRNVPQEEsLEDsDVDADFKAQNVTLEAILQNA
O14737 S119 SIGNOR|PSP PDCD5 TFAR19 VSQQTEKTTTVKFNRRKVMDsDEDDDy______________
O14950 T135 PSP MYL12B MRLC2 MYLC2B TGTIQEDYLRELLttMGDRFtDEEVDELyREAPIDKKGNFN
O14958 S385 SIGNOR|iPTMNet|PSP CASQ2 VLSGKINTEDDDEDDDDDDNsDEEDNDDsDDDDDE______
O14958 S393 PSP CASQ2 EDDDEDDDDDDNsDEEDNDDsDDDDDE______________
O15055 S696 PSP PER2 KIAA0347 IVHVGDKKPQPELEMVEDAAsGPEsLDCLAGPALACGLSQE
O15055 S700 PSP PER2 KIAA0347 GDKKPQPELEMVEDAAsGPEsLDCLAGPALACGLSQEKEPF
O15259 S121 SIGNOR|PSP NPHP1 NPH1 VTISRENITEVGAPTEEEEEsEsEDsEDSGGEEEDAEEEEE
O15259 S123 SIGNOR|PSP NPHP1 NPH1 ISRENITEVGAPTEEEEEsEsEDsEDSGGEEEDAEEEEEEK
O15259 S126 SIGNOR|PSP NPHP1 NPH1 ENITEVGAPTEEEEEsEsEDsEDSGGEEEDAEEEEEEKEEN
O15266 S106 SIGNOR|iPTMNet|PSP SHOX PHOG GTARVAEGIYECKEKREDVKsEDEDGQTKLKQRRSRTNFTL
O15379 S424 SIGNOR|iPTMNet|PSP HDAC3 YSRPEAPNEFYDGDHDNDKEsDVEI________________
O15392 T48 PSP BIRC5 API4 IAP4 LEGCACtPERMAEAGFIHCPtENEPDLAQCFFCFKELEGWE
O15460 S346 Sugiyama P4HA2 UNQ290/PRO330 PFKEEDEWDSPHIVRYyDVMsDEEIERIKEIAKPKLARATV
O43156 S828 SIGNOR|PSP TTI1 KIAA0406 SMG10 DIEQFLLNYLKEKDVADGNVsDFDNEEEEQSVPPKVDENDT
O43242 S6 PSP PSMD3 _______________MKQEGsARRRGADKAKPPPGGGEQEP
O43395 T494 SIGNOR|PSP PRPF3 HPRP3 PRP3 PKVRISNLMRVLGTEAVQDPtKVEAHVRAQMAKRQKAHEEA
O43719 S642 Sugiyama HTATSF1 EDsDEKEEEEDtyEKVFDDEsDEKEDEEyADEKGLEAADKK
O43719 S748 PSP HTATSF1 GGFGSVEEGPLSTGSSFILssDDDDDDI_____________
O43852 S261 Sugiyama CALU RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK
O43889 S46 SIGNOR|PSP CREB3 LZIP APDEAVRAPLDWALPLSEVPsDWEVDDLLCSLLSPPASLNI
O43896 S1092 SIGNOR|ELM|iPTMNet KIF1C KIAA0706 RPPGPRYPPYttPPRMRRQRsAPDLKESGAAV_________
O60231 S103 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 AEREARALLEKNRSYRLLEDsEEssEEtVsRAGsSLQKKRK
O60231 S106 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 EARALLEKNRSYRLLEDsEEssEEtVsRAGsSLQKKRKKRK
O60341 S131 SIGNOR|PSP KDM1A AOF2 KDM1 KIAA0601 LSD1 sRRKRAKVEyREMDEsLANLsEDEyysEEERNAKAEKEKKL
O60341 S137 SIGNOR|PSP KDM1A AOF2 KDM1 KIAA0601 LSD1 KVEyREMDEsLANLsEDEyysEEERNAKAEKEKKLPPPPPQ
O60671 S280 PSP RAD1 REC1 EDGQICFVEYYCCPDEEVPEsEs__________________
O60671 S282 PSP RAD1 REC1 GQICFVEYYCCPDEEVPEsEs____________________
O60841 S113 Sugiyama EIF5B IF2 KIAA0741 sKDKKKKGQKGKKQsFDDNDsEELEDKDsKSKKTAKPKVEM
O60841 S137 Sugiyama EIF5B IF2 KIAA0741 EDKDsKSKKTAKPKVEMysGsDDDDDFNKLPKKAKGKAQKS
O60841 S214 Sugiyama EIF5B IF2 KIAA0741 LQsRKGQKKNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAE
O60927 S73 Sugiyama PPP1R11 HCGV TCTE5 MGRRssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRG
O60927 T75 Sugiyama PPP1R11 HCGV TCTE5 RRssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRGHR
O60936 T149 SIGNOR|iPTMNet|PSP NOL3 ARC NOP RASDPDEAGGPEGsEAVQsGtPEEPEPELEAEAsKEAEPEP
O75376 S2436 PSP NCOR1 KIAA1047 QNRIWEREPAPLLSAQYEtLsDsDD________________
O75379 S30 SIGNOR|ELM|iPTMNet VAMP4 NDDDVTGsVKsERRNLLEDDsDEEEDFFLRGPSGPRFGPRN
O75496 S184 PSP GMNN DNFESLDNQEFDSEEETVEDsLVEDSEIGTCAEGTVssstD
O75582 S757 PSP RPS6KA5 MSK1 KAPLAKRRKMKKTsTsTETRssssESSHSSSsHSHGKTTPT
O75582 S758 PSP RPS6KA5 MSK1 APLAKRRKMKKTsTsTETRssssESSHSSSsHSHGKTTPTK
O75582 S759 PSP RPS6KA5 MSK1 PLAKRRKMKKTsTsTETRssssESSHSSSsHSHGKTTPTKT
O75582 S760 PSP RPS6KA5 MSK1 LAKRRKMKKTsTsTETRssssESSHSSSsHSHGKTTPTKTL
O75582 T793 PSP RPS6KA5 MSK1 KTTPTKTLQPSNPADsNNPEtLFQFSDsVA___________
O75676 S324 SIGNOR|PSP RPS6KA4 MSK2 LDWVALAARKIPAPFRPQIRsELDVGNFAEEFTRLEPVysP
O75822 S127 SIGNOR|PSP EIF3J EIF3S1 PRO0391 VLtPEEQLADKLRLKKLQEEsDLELAKEtFGVNNAVyGIDA
O75925 S466 SIGNOR|PSP PIAS1 DDXBP1 SHHQSSNKNKKVEVIDLTIDsssDEEEEEPSAKRTCPsLsP
O75925 S467 SIGNOR|PSP PIAS1 DDXBP1 HHQSSNKNKKVEVIDLTIDsssDEEEEEPSAKRTCPsLsPt
O75925 S468 SIGNOR|PSP PIAS1 DDXBP1 HQSSNKNKKVEVIDLTIDsssDEEEEEPSAKRTCPsLsPts
O75943 S678 PSP RAD17 R24L PQPFSAQGDMEENIIIEDyEsDGt_________________
O76021 S361 Sugiyama RSL1D1 CATX11 CSIG PBK1 L12 PEHGKKKRGRGKAQVKAtNEsEDEIPQLVPIGKKtPANEKV
O76061 S288 GPS6|ELM|PSP STC2 PNAHARGRVGGLGAQGPsGssEWEDEQSEYSDIRR______
O95218 S120 Sugiyama ZRANB2 ZIS ZNF265 tGYGGGFNERENVEyIEREEsDGEyDEFGRKKKKYRGKAVG
O95218 S153 Sugiyama ZRANB2 ZIS ZNF265 KYRGKAVGPAsILKEVEDKEsEGEEEDEDEDLsKyKLDEDE
O95218 S188 Sugiyama ZRANB2 ZIS ZNF265 KLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRRSRSKSRS
O95477 S1255 GPS6|ELM|PSP ABCA1 ABC1 CERP SSYGISEttLEEIFLKVAEEsGVDAETSDGTLPARRNRRAF
O95477 T1242 GPS6|ELM|PSP ABCA1 ABC1 CERP FHEIDDRLSDLGISSYGISEttLEEIFLKVAEEsGVDAETS
O95477 T1243 GPS6|ELM|PSP ABCA1 ABC1 CERP HEIDDRLSDLGISSYGISEttLEEIFLKVAEEsGVDAETSD
O95786 S854 GPS6|SIGNOR|PSP RIGI DDX58 LGDAFKECFVSRPHPKPKQFssFEKRAKIFCARQNCSHDWG
O95786 S855 GPS6|SIGNOR|PSP RIGI DDX58 GDAFKECFVSRPHPKPKQFssFEKRAKIFCARQNCSHDWGI
O95786 T770 GPS6|SIGNOR|PSP RIGI DDX58 KEQINMYKEKMMNDsILRLQtWDEAVFREKILHIQTHEKFI
O95816 S73 Sugiyama BAG2 KEILLEMIHSIQNSQDMRQIsDGEREELNLTANRLMGRTLT
O95863 S11 SIGNOR SNAI1 SNAH __________MPRSFLVRKPsDPNRKPNYSELQDSNPEFTF
O95863 S92 SIGNOR|PSP SNAI1 SNAH IAWASLRLQEsPRVAELTSLsDEDsGKGsQPPsPPsPAPsS
O95905 S503 PSP ECD FDADSFLNYFDKILGPRPNEsDsDDLDDEDFECLDsDDDLD
O95905 S505 PSP ECD ADSFLNYFDKILGPRPNEsDsDDLDDEDFECLDsDDDLDFE
O95905 S518 PSP ECD PRPNEsDsDDLDDEDFECLDsDDDLDFETHEPGEEASLKGT
P00374 S145 GPS6|PSP DHFR AMNHPGHLKLFVTRIMQDFEsDTFFPEIDLEKYKLLPEYPG
P00374 S168 GPS6|PSP DHFR FFPEIDLEKYKLLPEYPGVLsDVQEEKGIKYKFEVyEKND_
P00558 S256 PSP PGK1 PGKA MIG10 OK/SW-cl.110 IGGGMAFtFLKVLNNMEIGTsLFDEEGAKIVKDLMSKAEKN
P00736 S206 GPS6|SIGNOR|ELM|iPTMNet|PSP C1R THSCQAECSSELYTEASGYIsSLEYPRSYPPDLRCNYSIRV
P01106 S264 PSP MYC BHLHE39 SSPQGSPEPLVLHEEtPPTtssDsEEEQEDEEEIDVVSVEK
P01106 S265 PSP MYC BHLHE39 SPQGSPEPLVLHEEtPPTtssDsEEEQEDEEEIDVVSVEKR
P01106 S267 SIGNOR|PSP MYC BHLHE39 QGSPEPLVLHEEtPPTtssDsEEEQEDEEEIDVVSVEKRQA
P01106 S362 PSP MYC BHLHE39 LDSVRVLRQISNNRKCtsPRssDTEENVKRRtHNVLERQRR
P01106 S363 PSP MYC BHLHE39 DSVRVLRQISNNRKCtsPRssDTEENVKRRtHNVLERQRRN
P01106 T73 iPTMNet MYC BHLHE39 SELQPPAPSEDIWKKFELLPtPPLsPsRRsGLCsPSyVAVT
P01375 S2 ELM TNF TNFA TNFSF2 ___________________MsTESMIRDVELAEEALPKKTG
P02649 S314 PSP APOE WAGLVEKVQAAVGTSAAPVPsDNH_________________
P02671 S542 PSP FGA tAstGKTFPGFFsPMLGEFVsEtEsRGsEsGIFtNtKEsss
P02671 S609 PSP FGA YNRGDstFESKSYKMADEAGsEADHEGTHsTKRGHAKSRPV
P03372 S167 PSP ESR1 ESR NR3A1 PAFYRPNsDNRRQGGRERLAsTNDKGSMAMESAKETRYCAV
P03372 S282 GPS6|SIGNOR|PSP ESR1 ESR NR3A1 GRMLKHKRQRDDGEGRGEVGsAGDMRAANLWPsPLMIKRSK
P03372 S559 GPS6|SIGNOR|PSP ESR1 ESR NR3A1 LLLEMLDAHRLHAPTsRGGAsVEETDQSHLATAGSTSsHsL
P04004 T69 GPS6|SIGNOR|ELM|iPTMNet|PSP VTN SCCTDYTAECKPQVTRGDVFtMPEDEYtVYDDGEEKNNATV
P04004 T76 GPS6|SIGNOR|ELM|iPTMNet|PSP VTN AECKPQVTRGDVFtMPEDEYtVYDDGEEKNNATVHEQVGGP
P04198 S261 GPS6|SIGNOR|ELM|iPTMNet|PSP MYCN BHLHE37 NMYC GRQTSGGDHKALSTSGEDTLsDsDDEDDEEEDEEEEIDVVT
P04198 S263 GPS6|SIGNOR|ELM|iPTMNet|PSP MYCN BHLHE37 NMYC QTSGGDHKALSTSGEDTLsDsDDEDDEEEDEEEEIDVVTVE
P04637 S149 PSP TP53 P53 ALNKMFCQLAKTCPVQLWVDstPPPGtRVRAMAIYKQSQHM
P04637 S392 SIGNOR|iPTMNet|PSP TP53 P53 KKGQstsRHKKLMFKtEGPDsD___________________
P04637 S46 PSP TP53 P53 LPENNVLsPLPsQAMDDLMLsPDDIEQWFtEDPGPDEAPRM
P04637 S6 PSP TP53 P53 _______________MEEPQsDPsVEPPLsQEtFsDLWKLL
P04637 T150 PSP TP53 P53 LNKMFCQLAKTCPVQLWVDstPPPGtRVRAMAIYKQSQHMT
P04637 T155 SIGNOR|iPTMNet|PSP TP53 P53 CQLAKTCPVQLWVDstPPPGtRVRAMAIYKQSQHMTEVVRR
P04637 T18 iPTMNet TP53 P53 ___MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQ
P04637 T55 PSP TP53 P53 LPsQAMDDLMLsPDDIEQWFtEDPGPDEAPRMPEAAPPVAP
P04818 S124 GPS6|PSP TYMS TS OK/SW-cl.29 KGVKIWDANGsRDFLDsLGFsTREEGDLGPVyGFQWRHFGA
P05114 S7 SIGNOR|PSP HMGN1 HMG14 ______________MPKRKVssAEGAAKEEPKRRsARLsAK
P05114 S8 SIGNOR|PSP HMGN1 HMG14 _____________MPKRKVssAEGAAKEEPKRRsARLsAKP
P05114 S86 PSP HMGN1 HMG14 ANQETKEDLPAENGEtKtEEsPAsDEAGEKEAKsD______
P05114 S89 SIGNOR|PSP HMGN1 HMG14 ETKEDLPAENGEtKtEEsPAsDEAGEKEAKsD_________
P05114 S99 SIGNOR|PSP HMGN1 HMG14 GEtKtEEsPAsDEAGEKEAKsD___________________
P05198 T279 Sugiyama EIF2S1 EIF2A KEKIEEKRGVFNVQMEPKVVtDtDEtELARQMERLERENAE
P05386 S101 Sugiyama RPLP1 RRP1 APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S102 Sugiyama RPLP2 D11S2243E RPP2 PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05388 S304 Sugiyama RPLP0 AttAAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD_______
P05388 S307 Sugiyama RPLP0 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
P05412 S243 ELM|PSP JUN QALKEEPQtVPEMPGEtPPLsPIDMEsQERIKAERKRMRNR
P05412 S249 SIGNOR|ELM|iPTMNet|PSP JUN PQtVPEMPGEtPPLsPIDMEsQERIKAERKRMRNRIAASKC
P05412 T231 GPS6|SIGNOR|ELM|iPTMNet|PSP JUN LPQQMPVQHPRLQALKEEPQtVPEMPGEtPPLsPIDMEsQE
P05455 S366 GPS6|SIGNOR|ELM|PSP|Sugiyama SSB AQPGsGKGKVQFQGKKtKFAsDDEHDEHDENGAtGPVKRAR
P05549 S429 SIGNOR|PSP TFAP2A AP2TF TFAP2 MDKMYLSNNPNSHTDNNAKSsDKEEKHRK____________
P06127 S482 GPS6|SIGNOR|ELM|iPTMNet|PSP CD5 LEU1 LSAyPALEGALHRSSMQPDNssDsDyDLHGAQRL_______
P06127 S483 GPS6|SIGNOR|ELM|iPTMNet|PSP CD5 LEU1 SAyPALEGALHRSSMQPDNssDsDyDLHGAQRL________
P06127 S485 GPS6|SIGNOR|ELM|iPTMNet|PSP CD5 LEU1 yPALEGALHRSSMQPDNssDsDyDLHGAQRL__________
P06401 S81 GPS6|SIGNOR|ELM|iPTMNet|PSP PGR NR3C3 PRPCQGQDPSDEKTQDQQSLsDVEGAYSRAEATRGAGGSSS
P06454 T13 ELM PTMA TMSA ________MsDAAVDtssEIttKDLKEKKEVVEEAENGRDA
P06454 T14 ELM PTMA TMSA _______MsDAAVDtssEIttKDLKEKKEVVEEAENGRDAP
P06454 T8 ELM PTMA TMSA _____________MsDAAVDtssEIttKDLKEKKEVVEEAE
P06493 S39 GPS6|SIGNOR|ELM|PSP CDK1 CDC2 CDC28A CDKN1 P34CDC2 yKGRHKTTGQVVAMKKIRLEsEEEGVPstAIREIsLLKELR
P06744 S185 SIGNOR|ELM|iPTMNet|PSP GPI LMVTEALKPYSsGGPRVWYVsNIDGTHIAKTLAQLNPESSL
P06748 S125 PSP|Sugiyama NPM1 NPM GsGPVHIsGQHLVAVEEDAEsEDEEEEDVKLLsIsGKRsAP
P07900 S231 SIGNOR|ELM HSP90AA1 HSP90A HSPC1 HSPCA SQFIGyPITLFVEKERDKEVsDDEAEEKEDKEEEKEKEEKE
P07900 S263 GPS6|SIGNOR|ELM|PSP|Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EEKEKEEKEsEDKPEIEDVGsDEEEEKKDGDKKKKKKIKEK
P07900 S391 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P07900 S726 PSP HSP90AA1 HSP90A HSPC1 HSPCA DDtsAAVtEEMPPLEGDDDtsRMEEVD______________
P07900 T36 PSP HSP90AA1 HSP90A HSPC1 HSPCA EVETFAFQAEIAQLMSLIINtFySNKEIFLRELIsNssDAL
P07900 T725 PSP HSP90AA1 HSP90A HSPC1 HSPCA ADDtsAAVtEEMPPLEGDDDtsRMEEVD_____________
P07910 S260 SIGNOR|ELM|iPTMNet|PSP HNRNPC HNRPC ssVKKDETNVKMEsEGGADDsAEEGDLLDDDDNEDRGDDQL
P08047 T579 SIGNOR|ELM|iPTMNet SP1 TSFP1 GDHGAQLGLHGAGGDGIHDDtAGGEEGENSPDAQPQAGRRT
P08195 S406 PSP SLC3A2 MDU1 QQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNAT
P08195 S408 PSP SLC3A2 MDU1 ILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNATGN
P08195 S410 PSP SLC3A2 MDU1 SLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNATGNRW
P08195 S527 PSP SLC3A2 MDU1 MTVKGQsEDPGsLLsLFRRLsDQRsKERSLLHGDFHAFSAG
P08195 S531 PSP SLC3A2 MDU1 GQsEDPGsLLsLFRRLsDQRsKERSLLHGDFHAFSAGPGLF
P08235 S111 PSP NR3C2 MCR MLR ELESKELSATVAESMGLYMDsVRDADYSYEQQNQQGSMSPA
P08235 S459 PSP NR3C2 MCR MLR TSFKGNPTVNPFPFMDGSYFsFMDDKDYYSLSGILGPPVPG
P08238 S226 GPS6|SIGNOR|ELM|PSP HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sQFIGyPItLyLEKEREKEIsDDEAEEEKGEKEEEDKDDEE
P08238 S255 GPS6|SIGNOR|ELM|PSP HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GEKEEEDKDDEEKPKIEDVGsDEEDDsGKDKKKKTKKIKEK
P08238 S383 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S718 PSP HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EEPNAAVPDEIPPLEGDEDAsRMEEVD______________
P08473 S6 SIGNOR|PSP MME EPN _______________MGKsEsQMDItDINtPKPKKKQRWTP
P08575 S1001 SIGNOR PTPRC CD45 DYNRVPLKHELEMSKESEHDsDEssDDDsDSEEPSKYINAS
P08575 S1004 SIGNOR PTPRC CD45 RVPLKHELEMSKESEHDsDEssDDDsDSEEPSKYINASFIM
P08575 S1005 SIGNOR PTPRC CD45 VPLKHELEMSKESEHDsDEssDDDsDSEEPSKYINASFIMS
P08575 S1009 SIGNOR PTPRC CD45 HELEMSKESEHDsDEssDDDsDSEEPSKYINASFIMSYWKP
P08758 S136 Sugiyama ANXA5 ANX5 ENX2 PP4 sRtPEELRAIKQVyEEEyGssLEDDVVGDTSGYYQRMLVVL
P08833 S126 PSP IGFBP1 IBP1 QESDASAPHAAEAGSPEsPEsTEITEEELLDNFHLMAPsEE
P08833 S144 PSP IGFBP1 IBP1 PEsTEITEEELLDNFHLMAPsEEDHSILWDAISTYDGSKAL
P08833 S194 PSP IGFBP1 IBP1 EPCRIELYRVVESLAKAQETsGEEIsKFYLPNCNKNGFYHS
P09497 S11 SIGNOR|iPTMNet CLTB __________MADDFGFFSSsEsGAPEAAEEDPAAAFLAQQ
P09497 S13 SIGNOR|iPTMNet CLTB ________MADDFGFFSSsEsGAPEAAEEDPAAAFLAQQES
P09629 S132 PSP HOXB7 HOX2C EQRDSDLAAESNFRIYPWMRssGTDRKRGRQTYTRYQTLEL
P09629 S133 SIGNOR|ELM|iPTMNet|PSP HOXB7 HOX2C QRDSDLAAESNFRIYPWMRssGTDRKRGRQTYTRYQTLELE
P09629 T203 PSP HOXB7 HOX2C IWFQNRRMKWKKENKTAGPGttGQDRAEAEEEEEE______
P09629 T204 SIGNOR|ELM|iPTMNet|PSP HOXB7 HOX2C WFQNRRMKWKKENKTAGPGttGQDRAEAEEEEEE_______
P09651 S199 GPS6|ELM|PSP HNRNPA1 HNRPA1 KALSKQEMAsAsssQRGRsGsGNFGGGRGGGFGGNDNFGRG
P09958 S773 PSP FURIN FUR PACE PCSK3 DRGLISYKGLPPEAWQEECPsDsEEDEGRGERTAFIKDQSA
P09958 S775 PSP FURIN FUR PACE PCSK3 GLISYKGLPPEAWQEECPsDsEEDEGRGERTAFIKDQSAL_
P0DMV8 T636 PSP HSPA1A HSP72 HSPA1 HSX70 GPGPGGFGAQGPKGGsGsGPtIEEVD_______________
P0DP23 S102 SIGNOR|ELM|PSP CALM1 CALM CAM CAM1 sEEEIREAFRVFDKDGNGyIsAAELRHVMTNLGEKLtDEEV
P0DP23 S82 SIGNOR|PSP CALM1 CALM CAM CAM1 GTIDFPEFLTMMARKMKDtDsEEEIREAFRVFDKDGNGyIs
P0DP23 T118 SIGNOR|PSP CALM1 CALM CAM CAM1 NGyIsAAELRHVMTNLGEKLtDEEVDEMIREADIDGDGQVN
P0DP23 T80 SIGNOR|ELM|PSP CALM1 CALM CAM CAM1 GNGTIDFPEFLTMMARKMKDtDsEEEIREAFRVFDKDGNGy
P10242 S11 GPS6|SIGNOR|ELM|iPTMNet|PSP MYB __________MARRPRHSIYssDEDDEDFEMCDHDYDGLLP
P10242 S12 GPS6|SIGNOR|ELM|iPTMNet|PSP MYB _________MARRPRHSIYssDEDDEDFEMCDHDYDGLLPK
P10243 S7 PSP MYBL1 AMYB ______________MAKRsRsEDEDDDLQYADHDYEVPQQK
P10244 T18 PSP MYBL2 BMYB ___MSRRTRCEDLDELHyQDtDsDVPEQRDsKCKVKWTHEE
P10646 S30 GPS6|ELM|PSP TFPI LACI TFPI1 ALWASVCLLLNLAPAPLNADsEEDEEHTIITDTELPPLKLM
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11274 S1264 GPS6|ELM BCR BCR1 D22S11 QVLLYFLQLEAIPAPDSKRQsILFSTEV_____________
P11387 S10 SIGNOR|PSP TOP1 ___________MsGDHLHNDsQIEADFRLNDsHKHKDKHKD
P11387 S506 PSP TOP1 ALRAGNEKEEGETADTVGCCsLRVEHINLHPELDGQEYVVE
P11388 S1365 SIGNOR|PSP TOP2A TOP2 DEDFVPsDAsPPKtKTsPKLsNKELKPQKsVVsDLEADDVK
P11388 S1377 GPS6|SIGNOR|ELM|iPTMNet|PSP TOP2A TOP2 KtKTsPKLsNKELKPQKsVVsDLEADDVKGsVPLsssPPAt
P11388 S1469 iPTMNet|PSP TOP2A TOP2 sGVsQKPDPAKTKNRRKRKPstsDDsDsNFEKIVSKAVTSK
P11388 S1525 GPS6|SIGNOR|ELM|iPTMNet|PSP TOP2A TOP2 AVAPRAKSVRAKKPIKYLEEsDEDDLF______________
P11388 T1343 SIGNOR|ELM|iPTMNet TOP2A TOP2 KTKFTMDLDsDEDFsDFDEKtDDEDFVPsDAsPPKtKTsPK
P11413 T145 SIGNOR G6PD MNALHLGsQANRLFYLALPPtVYEAVTKNIHESCMsQIGWN
P11473 S208 GPS6|SIGNOR|ELM|iPTMNet|PSP VDR NR1I1 DHCITSSDMMDSSSFSNLDLsEEDSDDPSVTLELSQLSMLP
P11717 S2409 GPS6|SIGNOR|ELM|PSP IGF2R MPRI GHITTKSVKALssLHGDDQDsEDEVLtIPEVKVHSGRGAGA
P11717 S2484 GPS6|SIGNOR|ELM|PSP IGF2R MPRI SSSAQQKTVSStKLVsFHDDsDEDLLHI_____________
P11831 S77 GPS6|SIGNOR|ELM|PSP SRF EREAAAAAATTPAPTAGALYsGsEGDsEsGEEEELGAERRG
P11831 S79 GPS6|SIGNOR|ELM|PSP SRF EAAAAAATTPAPTAGALYsGsEGDsEsGEEEELGAERRGLK
P11831 S83 GPS6|SIGNOR|ELM|iPTMNet|PSP SRF AAATTPAPTAGALYsGsEGDsEsGEEEELGAERRGLKRsLs
P11831 S85 SIGNOR|PSP SRF ATTPAPTAGALYsGsEGDsEsGEEEELGAERRGLKRsLsEM
P11836 S231 SIGNOR|ELM|iPTMNet MS4A1 CD20 IVENEWKRTCSRPKsNIVLLsAEEKKEQTIEIKEEVVGLtE
P11836 S289 SIGNOR|ELM|iPTMNet MS4A1 CD20 EEEEEETETNFPEPPQDQESsPIENDSSP____________
P11836 T250 SIGNOR|ELM|iPTMNet MS4A1 CD20 LsAEEKKEQTIEIKEEVVGLtEtssQPKNEEDIEIIPIQEE
P12259 S692 SIGNOR|ELM|iPTMNet F5 SKKLRLKFRDVKCIPDDDEDsyEIFEPPESTVMATRKMHDR
P12259 S720 GPS6|ELM|PSP F5 ESTVMATRKMHDRLEPEDEEsDADYDYQNRLAAALGIRSFR
P12821 S1299 SIGNOR|PSP ACE DCP DCP1 RLFSIRHRSLHRHSHGPQFGsEVELRHS_____________
P12830 S838 SIGNOR|iPTMNet CDH1 CDHE UVO ADTDPTAPPYDSLLVFDYEGsGsEAAsLSsLNssEsDKDQD
P12830 S847 iPTMNet|PSP CDH1 CDHE UVO YDSLLVFDYEGsGsEAAsLSsLNssEsDKDQDYDYLNEWGN
P12830 S850 PSP CDH1 CDHE UVO LLVFDYEGsGsEAAsLSsLNssEsDKDQDYDYLNEWGNRFK
P12830 S851 SIGNOR|ELM|iPTMNet CDH1 CDHE UVO LVFDYEGsGsEAAsLSsLNssEsDKDQDYDYLNEWGNRFKK
P12830 S853 SIGNOR|iPTMNet|PSP CDH1 CDHE UVO FDYEGsGsEAAsLSsLNssEsDKDQDYDYLNEWGNRFKKLA
P13349 S133 SIGNOR|ELM|iPTMNet|PSP MYF5 BHLHC2 NPNQRLPKVEILRNAIRYIEsLQELLREQVENYYSLPGQSC
P13349 S49 SIGNOR|ELM|iPTMNet|PSP MYF5 BHLHC2 GDEFVPRVAAFGAHKAELQGsDEDEHVRAPTGHHQAGHCLM
P13569 S422 SIGNOR|PSP CFTR ABCC7 EEGFGELFEKAKQNNNNRKtsNGDDsLFFSNFSLLGTPVLK
P13569 S427 PSP CFTR ABCC7 ELFEKAKQNNNNRKtsNGDDsLFFSNFSLLGTPVLKDINFK
P13569 S511 SIGNOR|PSP CFTR ABCC7 CSQFSWIMPGTIKENIIFGVsyDEYRYRSVIKACQLEEDIS
P13569 T1471 SIGNOR CFTR ABCC7 PHRNSSKCKSKPQIAALKEEtEEEVQDTRL___________
P13569 T421 PSP CFTR ABCC7 WEEGFGELFEKAKQNNNNRKtsNGDDsLFFSNFSLLGTPVL
P13798 S187 Sugiyama APEH D3F15S2 D3S48E DNF15S2 EKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQFV
P13807 S10 SIGNOR|iPTMNet GYS1 GYS ___________MPLNRTLsMssLPGLEDWEDEFDLENAVLF
P13807 S645 SIGNOR GYS1 GYS PNEADAAQGyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRN
P13807 S647 iPTMNet GYS1 GYS EADAAQGyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRNGP
P13807 S649 SIGNOR GYS1 GYS DAAQGyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRNGPLE
P13807 S652 iPTMNet GYS1 GYS QGyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRNGPLEEDG
P13807 S653 SIGNOR|iPTMNet GYS1 GYS GyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRNGPLEEDGE
P13807 S698 SIGNOR|iPTMNet GYS1 GYS DEEAAKDRRNIRAPEWPRRAsCTsSTSGSKRNsVDtAtsss
P13807 S701 iPTMNet GYS1 GYS AAKDRRNIRAPEWPRRAsCTsSTSGSKRNsVDtAtsssLst
P13807 T713 SIGNOR|iPTMNet GYS1 GYS WPRRAsCTsSTSGSKRNsVDtAtsssLstPsEPLsPtssLG
P13861 S78 Sugiyama PRKAR2A PKR2 PRKAR2 sLGHPPPEPGPDRVADAKGDsEsEEDEDLEVPVPsRFNRRV
P13861 S80 Sugiyama PRKAR2A PKR2 PRKAR2 GHPPPEPGPDRVADAKGDsEsEEDEDLEVPVPsRFNRRVsV
P14317 T16 SIGNOR|iPTMNet|PSP HCLS1 HS1 _____MWKSVVGHDVSVSVEtQGDDWDtDPDFVNDISEKEQ
P14317 T23 SIGNOR|iPTMNet|PSP HCLS1 HS1 KSVVGHDVSVSVEtQGDDWDtDPDFVNDISEKEQRWGAKTI
P14598 S208 ELM|PSP NCF1 NOXO2 SH3PXD1A KSESGWWFCQMKAKRGWIPAsFLEPLDSPDETEDPEPNyAG
P14598 S283 ELM|PSP NCF1 NOXO2 SH3PXD1A WWVIRKDDVTGYFPSMyLQKsGQDVsQAQRQIKRGAPPRRs
P14598 S348 ELM|PSP NCF1 NOXO2 SH3PXD1A sVRFLQQRRRQARPGPQsPGsPLEEERQtQRsKPQPAVPPR
P14625 S306 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 TETVEEPMEEEEAAKEEKEEsDDEAAVEEEEEEKKPKTKKV
P15884 S54 GPS6|ELM TCF4 BHLHB19 ITF2 SEF2 KNGPTSLASGHFTGSNVEDRsssGSWGNGGHPsPSRNYGDG
P15884 S55 GPS6|ELM TCF4 BHLHB19 ITF2 SEF2 NGPTSLASGHFTGSNVEDRsssGSWGNGGHPsPSRNYGDGT
P15884 S56 GPS6|ELM TCF4 BHLHB19 ITF2 SEF2 GPTSLASGHFTGSNVEDRsssGSWGNGGHPsPSRNYGDGTP
P16220 S94 PSP CREB1 QPSVIQSPQVQTVQISTIAEsEDsQEsVDsVTDsQKRREIL
P16220 S97 PSP CREB1 VIQSPQVQTVQISTIAEsEDsQEsVDsVTDsQKRREILsRR
P16949 S16 iPTMNet STMN1 C1orf215 LAP18 OP18 _____MAssDIQVKELEKRAsGQAFELILsPRsKEsVPEFP
P16949 S63 iPTMNet STMN1 C1orf215 LAP18 OP18 KDLsLEEIQKKLEAAEERRKsHEAEVLKQLAEKREHEKEVL
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P17096 S102 SIGNOR|ELM|iPTMNet|PSP HMGA1 HMGIY KPRGRPKKLEKEEEEGIsQEssEEEQ_______________
P17096 S103 SIGNOR|ELM|iPTMNet|PSP HMGA1 HMGIY PRGRPKKLEKEEEEGIsQEssEEEQ________________
P17096 S99 SIGNOR|ELM|iPTMNet HMGA1 HMGIY PGRKPRGRPKKLEKEEEEGIsQEssEEEQ____________
P17677 S202 SIGNOR|iPTMNet GAP43 PAAEDAAAKATAQPPTEtGEssQAEENIEAVDETKPKESAR
P17677 S203 SIGNOR|iPTMNet GAP43 AAEDAAAKATAQPPTEtGEssQAEENIEAVDETKPKESARQ
P17931 S12 iPTMNet LGALS3 MAC2 _________MADNFsLHDALsGSGNPNPQGWPGAWGNQPAG
P17931 S6 iPTMNet LGALS3 MAC2 _______________MADNFsLHDALsGSGNPNPQGWPGAW
P17936 S138 SIGNOR|ELM|iPTMNet|PSP IGFBP3 IBP3 SAVSRLRAYLLPAPPAPGNAsEsEEDRsAGsVEsPSVSsTH
P17936 S140 SIGNOR|ELM|iPTMNet|PSP IGFBP3 IBP3 VSRLRAYLLPAPPAPGNAsEsEEDRsAGsVEsPSVSsTHRV
P17936 S194 PSP IGFBP3 IBP3 IIKKGHAKDsQRYKVDYESQsTDtQNFssEsKRETEYGPCR
P18031 S352 iPTMNet PTPN1 PTP1B QWVKEEtQEDKDCPIKEEKGsPLNAAPYGIEsMsQDtEVRS
P18031 S378 iPTMNet PTPN1 PTP1B PYGIEsMsQDtEVRSRVVGGsLRGAQAAsPAKGEPsLPEKD
P18031 S386 iPTMNet PTPN1 PTP1B QDtEVRSRVVGGsLRGAQAAsPAKGEPsLPEKDEDHALSYW
P18146 S378 SIGNOR|ELM|iPTMNet EGR1 KROX24 ZNF225 HIRIHTGQKPFQCRICMRNFsRSDHLTTHIRTHtGEKPFAC
P18146 T391 SIGNOR|iPTMNet EGR1 KROX24 ZNF225 RICMRNFsRSDHLTTHIRTHtGEKPFACDICGRKFARSDER
P18146 T526 SIGNOR|iPTMNet EGR1 KROX24 ZNF225 FPAQVSSFPSSAVTNSFSAStGLSDMTATFSPRTIEIC___
P18846 S36 SIGNOR|ELM|iPTMNet|PSP ATF1 PGSAVQGAHISHIAQQVSSLsEsEEsQDsSDsIGssQKAHG
P18846 S38 SIGNOR ATF1 SAVQGAHISHIAQQVSSLsEsEEsQDsSDsIGssQKAHGIL
P18846 S41 SIGNOR|PSP ATF1 QGAHISHIAQQVSSLsEsEEsQDsSDsIGssQKAHGILARR
P18846 S44 SIGNOR ATF1 HISHIAQQVSSLsEsEEsQDsSDsIGssQKAHGILARRPsY
P18846 S47 PSP ATF1 HIAQQVSSLsEsEEsQDsSDsIGssQKAHGILARRPsYRKI
P18846 S50 PSP ATF1 QQVSSLsEsEEsQDsSDsIGssQKAHGILARRPsYRKILKD
P18846 S51 PSP ATF1 QVSSLsEsEEsQDsSDsIGssQKAHGILARRPsYRKILKDL
P18846 S63 SIGNOR ATF1 DsSDsIGssQKAHGILARRPsYRKILKDLsSEDTRGRKGDG
P18848 S184 PSP ATF4 CREB2 TXREB PLSPGVLSSTPDHSFSLELGsEVDITEGDRKPDYTAYVAMI
P18848 S215 SIGNOR|PSP ATF4 CREB2 TXREB PDYTAYVAMIPQCIKEEDTPsDNDsGICMsPESYLGSPQHS
P18858 S66 SIGNOR|ELM|iPTMNet|PSP LIG1 VsEsDsPVKRPGRKAARVLGsEGEEEDEALsPAKGQKPALD
P18887 S408 PSP XRCC1 DCHRMRRRLPSQRYLMAGPGsssEEDEAsHsGGsGDEAPKL
P18887 S409 PSP XRCC1 CHRMRRRLPSQRYLMAGPGsssEEDEAsHsGGsGDEAPKLP
P18887 S410 PSP XRCC1 HRMRRRLPSQRYLMAGPGsssEEDEAsHsGGsGDEAPKLPQ
P18887 S416 PSP XRCC1 LPSQRYLMAGPGsssEEDEAsHsGGsGDEAPKLPQKQPQTK
P18887 S418 PSP XRCC1 SQRYLMAGPGsssEEDEAsHsGGsGDEAPKLPQKQPQTKtK
P18887 S421 PSP XRCC1 YLMAGPGsssEEDEAsHsGGsGDEAPKLPQKQPQTKtKPtQ
P18887 S461 iPTMNet XRCC1 QAAGPssPQKPPtPEEtKAAsPVLQEDIDIEGVQsEGQDNG
P18887 S475 GPS6|SIGNOR|ELM|iPTMNet|PSP XRCC1 EEtKAAsPVLQEDIDIEGVQsEGQDNGAEDsGDtEDELRRV
P18887 S485 GPS6|SIGNOR|ELM|iPTMNet|PSP XRCC1 QEDIDIEGVQsEGQDNGAEDsGDtEDELRRVAEQKEHRLPP
P18887 S518 GPS6|SIGNOR|ELM|PSP XRCC1 QKEHRLPPGQEENGEDPyAGstDENtDsEEHQEPPDLPVPE
P18887 S525 GPS6|ELM|PSP XRCC1 PGQEENGEDPyAGstDENtDsEEHQEPPDLPVPELPDFFQG
P18887 S578 PSP XRCC1 ERRKLIRYVTAFNGELEDYMsDRVQFVITAQEWDPSFEEAL
P18887 T488 GPS6|SIGNOR|ELM|PSP XRCC1 IDIEGVQsEGQDNGAEDsGDtEDELRRVAEQKEHRLPPGQE
P18887 T519 GPS6|SIGNOR|ELM|iPTMNet|PSP XRCC1 KEHRLPPGQEENGEDPyAGstDENtDsEEHQEPPDLPVPEL
P18887 T523 GPS6|SIGNOR|ELM|PSP XRCC1 LPPGQEENGEDPyAGstDENtDsEEHQEPPDLPVPELPDFF
P18887 Y515 PSP XRCC1 VAEQKEHRLPPGQEENGEDPyAGstDENtDsEEHQEPPDLP
P19447 S751 GPS6|SIGNOR|ELM|PSP ERCC3 XPB XPBC GEFGSRSSQASRRFGTMSSMsGADDTVYMEYHSSRSKAPSK
P20042 S2 SIGNOR|iPTMNet|PSP EIF2S2 EIF2B ___________________MsGDEMIFDPtMsKKKKKKKKP
P20042 S67 SIGNOR|iPTMNet|PSP EIF2S2 EIF2B EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK
P20810 S655 SIGNOR|PSP CAST TKKSEDSKKPADDQDPIDALsGDLDsCPstTETsQNTAKDK
P21127 S283 Sugiyama CDK11B CDC2L1 CDK11 PITSLREA PK58 AQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSAESGSGS
P21673 S146 SIGNOR|ELM|iPTMNet|PSP SAT1 SAT HFLVAEWNEPSINFYKRRGAsDLsSEEGWRLFKIDKEYLLK
P21673 S149 SIGNOR|ELM|iPTMNet|PSP SAT1 SAT VAEWNEPSINFYKRRGAsDLsSEEGWRLFKIDKEYLLKMAT
P21673 T10 ELM|iPTMNet SAT1 SAT ___________MAKFVIRPAtAADCSDILRLIKELAKYEYM
P22314 S13 ELM UBA1 A1S9T UBE1 ________MSSsPLSKKRRVsGPDPKPGsNCsPAQsVLsEV
P22736 S152 PSP NR4A1 GFRP1 HMR NAK1 YGSPCSAPsPStPSFQPPQLsPWDGSFGHFSPSQTYEGLRA
P23760 S205 PSP PAX3 HUP2 KHSIDGILSERAsAPQsDEGsDIDsEPDLPLKRKQRRSRTT
P24046 S402 iPTMNet GABRR1 KLPCTSGLPPPRtAMLDGNYsDGEVNDLDNYMPENGEKPDR
P24534 S106 SIGNOR|iPTMNet EEF1B2 EEF1B EF1B DttGsGAtDsKDDDDIDLFGsDDEEEsEEAKRLREERLAQY
P24534 S112 SIGNOR|iPTMNet EEF1B2 EEF1B EF1B AtDsKDDDDIDLFGsDDEEEsEEAKRLREERLAQYESKKAK
P25205 S711 Sugiyama MCM3 RRKTRQPDAKDGDsyDPyDFsDtEEEMPQVHtPKTADsQEt
P25490 S118 SIGNOR|PSP YY1 INO80S HHHQEVILVQTREEVVGGDDsDGLRAEDGFEDQILIPVPAP
P25686 S247 PSP DNAJB2 HSJ1 HSPF3 VTSRSGGTQVQQtPAsCPLDsDLsEDEDLQLAMAYSLsEME
P25686 S250 PSP DNAJB2 HSJ1 HSPF3 RSGGTQVQQtPAsCPLDsDLsEDEDLQLAMAYSLsEMEAAG
P25686 S264 PSP DNAJB2 HSJ1 HSPF3 PLDsDLsEDEDLQLAMAYSLsEMEAAGKKPAGGREAQHRRQ
P25788 S243 SIGNOR|ELM|iPTMNet PSMA3 HC8 PSC8 GRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM________
P25788 S250 SIGNOR|ELM|Sugiyama PSMA3 HC8 PSC8 KDIREEAEKyAKEsLKEEDEsDDDNM_______________
P25963 S283 GPS6|SIGNOR|ELM|iPTMNet|PSP NFKBIA IKBA MAD3 NFKBI TRIQQQLGQLTLENLQMLPEsEDEEsyDtEsEFTEFtEDEL
P25963 S288 GPS6|SIGNOR|ELM|iPTMNet|PSP NFKBIA IKBA MAD3 NFKBI QLGQLTLENLQMLPEsEDEEsyDtEsEFTEFtEDELPyDDC
P25963 S293 GPS6|SIGNOR|ELM|iPTMNet|PSP NFKBIA IKBA MAD3 NFKBI TLENLQMLPEsEDEEsyDtEsEFTEFtEDELPyDDCVFGGQ
P25963 S32 SIGNOR|ELM|iPTMNet|PSP NFKBIA IKBA MAD3 NFKBI AMEGPRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEI
P25963 S36 SIGNOR|ELM|iPTMNet|PSP NFKBIA IKBA MAD3 NFKBI PRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEIRLEP
P25963 T291 GPS6|SIGNOR|ELM|iPTMNet|PSP NFKBIA IKBA MAD3 NFKBI QLTLENLQMLPEsEDEEsyDtEsEFTEFtEDELPyDDCVFG
P25963 T299 PSP NFKBIA IKBA MAD3 NFKBI MLPEsEDEEsyDtEsEFTEFtEDELPyDDCVFGGQRLTL__
P27348 S232 SIGNOR|PSP YWHAQ KDstLIMQLLRDNLTLWtsDsAGEECDAAEGAEN_______
P27540 S77 SIGNOR|iPTMNet|PSP ARNT BHLHE2 sKFLRCDDDQMsNDKERFARsDDEQsSADKERLARENHSEI
P27695 S123 SIGNOR|iPTMNet APEX1 APE APE1 APEX APX HAP1 REF1 KLPAELQELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVs
P27695 S290 ELM APEX1 APE APE1 APEX APX HAP1 REF1 MMNARSKNVGWRLDYFLLSHsLLPALCDSKIRSKALGSDHC
P27824 S554 ELM|Sugiyama CANX EKDKGDEEEEGEEKLEEKQKsDAEEDGGtVsQEEEDRKPKA
P27824 S564 ELM CANX GEEKLEEKQKsDAEEDGGtVsQEEEDRKPKAEEDEILNRsP
P27986 S608 SIGNOR|PSP PIK3R1 GRB1 GVRQKKLNEWLGNENtEDQysLVEDDEDLPHHDEKTWNVGS
P28482 S246 PSP MAPK1 ERK2 PRKM1 PRKM2 PIFPGKHYLDQLNHILGILGsPsQEDLNCIINLKARNYLLS
P28482 S248 PSP MAPK1 ERK2 PRKM1 PRKM2 FPGKHYLDQLNHILGILGsPsQEDLNCIINLKARNYLLSLP
P29590 S518 SIGNOR PML MYL PP8675 RNF71 TRIM19 EARLARssPEQPRPstsKAVsPPHLDGPPsPRsPVIGsEVF
P29590 S560 PSP PML MYL PP8675 RNF71 TRIM19 PNSNHVAsGAGEAEERVVVIsssEDsDAENSSSRELDDsss
P29590 S561 PSP PML MYL PP8675 RNF71 TRIM19 NSNHVAsGAGEAEERVVVIsssEDsDAENSSSRELDDsssE
P29590 S562 PSP PML MYL PP8675 RNF71 TRIM19 SNHVAsGAGEAEERVVVIsssEDsDAENSSSRELDDsssEs
P29590 S565 SIGNOR|PSP PML MYL PP8675 RNF71 TRIM19 VAsGAGEAEERVVVIsssEDsDAENSSSRELDDsssEssDL
P29692 S162 SIGNOR|PSP|Sugiyama EEF1D EF1D AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY
P30203 S480 PSP CD6 PKEVFMLPIQVQAPPPEDSDsGsDsDYEHYDFSAQPPVALT
P30203 S482 PSP CD6 EVFMLPIQVQAPPPEDSDsGsDsDYEHYDFSAQPPVALTTF
P30203 S484 PSP CD6 FMLPIQVQAPPPEDSDsGsDsDYEHYDFSAQPPVALTTFYN
P30260 S154 SIGNOR|PSP CDC27 ANAPC3 D0S1430E D17S978E GSECYQKSLSLNPFLWSPFEsLCEIGEKPDPDQTFKFTSLQ
P30291 S121 GPS6|SIGNOR|PSP WEE1 GADEAGGGAEGDSWEEEGFGsSsPVKsPAAPyFLGssFsPV
P30305 S186 GPS6|SIGNOR|ELM|PSP CDC25B CDC25HU2 ItNsQAPDGRRKsEAGSGAAssSGEDKENDGFVFKMPWKPT
P30305 S187 GPS6|SIGNOR|ELM|PSP CDC25B CDC25HU2 tNsQAPDGRRKsEAGSGAAssSGEDKENDGFVFKMPWKPTH
P30307 T236 SIGNOR|PSP CDC25C sMPENLNRPRLKQVEKFKDNtIPDKVKKKYFsGQGKLRKGL
P30519 S79 SIGNOR|iPTMNet HMOX2 HO2 KGNIKKELFKLATTALYFTYsALEEEMERNKDHPAFAPLYF
P30533 T248 Sugiyama LRPAP1 A2MRAP LRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWDLAQSAN
P30622 S1364 SIGNOR|PSP CLIP1 CYLN1 RSN VEMMSEAALNGNGDDLNNYDsDDQEKQsKKKPRLFCDICDC
P30793 S81 PSP GCH1 DYT5 GCH EEDNELNLPNLAAAYSSILSsLGENPQRQGLLKTPWRAASA
P31327 T1022 Sugiyama CPS1 TLRQLGKKTVVVNCNPETVstDFDECDKLyFEELSLERILD
P31749 S129 GPS6|SIGNOR|ELM|PSP AKT1 PKB RAC GLKKQEEEEMDFRsGsPsDNsGAEEMEVsLAKPKHRVtMNE
P31751 S131 PSP AKT2 KQRAPGEDPMDyKCGsPsDssttEEMEVAVSKARAKVTMND
P32004 S1181 SIGNOR|ELM|PSP L1CAM CAML1 MIC5 VDsEARPMKDEtFGEyRsLEsDNEEKAFGssQPsLNGDIKP
P32004 T1172 PSP L1CAM CAML1 MIC5 sVKDKEDtQVDsEARPMKDEtFGEyRsLEsDNEEKAFGssQ
P32121 T382 GPS6|SIGNOR|ELM|iPTMNet|PSP ARRB2 ARB2 ARR2 APETDVPVDTNLIEFDTNYAtDDDIVFEDFARLRLKGMKDD
P33527 T249 SIGNOR|PSP ABCC1 MRP MRP1 VRGYRQPLEGSDLWSLNKEDtSEQVVPVLVKNWKKECAKTR
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34932 S415 Sugiyama HSPA4 APG2 HSPH2 TDVVPYPISLRWNsPAEEGssDCEVFSKNHAAPFSKVLTFy
P35221 S641 GPS6|SIGNOR|PSP CTNNA1 GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35222 S29 SIGNOR|iPTMNet CTNNB1 CTNNB OK/SW-cl.35 PRO2286 ELDMAMEPDRKAAVsHWQQQsyLDsGIHsGATtTAPsLsGK
P35222 T102 SIGNOR|ELM|iPTMNet CTNNB1 CTNNB OK/SW-cl.35 PRO2286 IDGQyAMTRAQRVRAAMFPEtLDEGMQIPStQFDAAHPtNV
P35222 T112 SIGNOR|ELM|iPTMNet CTNNB1 CTNNB OK/SW-cl.35 PRO2286 QRVRAAMFPEtLDEGMQIPStQFDAAHPtNVQRLAEPSQML
P35222 T393 SIGNOR|ELM|iPTMNet CTNNB1 CTNNB OK/SW-cl.35 PRO2286 PsQRLVQNCLWtLRNLSDAAtKQEGMEGLLGTLVQLLGSDD
P35226 S110 SIGNOR|PSP BMI1 PCGF4 RNF51 EMKRRRDFYAAHPSADAANGsNEDRGEVADEDKRIITDDEI
P35568 S24 SIGNOR|ELM IRS1 PPEsDGFSDVRKVGYLRKPKsMHKRFFVLRAAsEAGGPARL
P35568 S330 SIGNOR IRS1 AtsPAsMVGGKPGsFRVRAssDGEGtMsRPAsVDGsPVsPs
P35568 S99 SIGNOR IRS1 KNKHLVALYtRDEHFAIAADsEAEQDSWYQALLQLHNRAKG
P35568 T502 SIGNOR|iPTMNet IRS1 HYILsRGGNGHRCtPGtGLGtsPALAGDEAASAADLDNRFR
P35568 T811 SIGNOR IRS1 LSTsSGRLLYAATADDSSSStSSDSLGGGYCGARLEPSLPH
P35568 T88 SIGNOR IRS1 SCFNINKRADSKNKHLVALYtRDEHFAIAADsEAEQDSWYQ
P35579 S1916 PSP MYH9 LQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMAR
P35579 S1943 SIGNOR|PSP|Sugiyama MYH9 RGDLPFVVPRRMARKGAGDGsDEEVDGKADGAEAKPAE___
P35580 S1952 PSP MYH10 GPIsFsssRSGRRQLHLEGAsLELsDDDtEsKtsDVNEtQP
P35580 S1956 PSP MYH10 FsssRSGRRQLHLEGAsLELsDDDtEsKtsDVNEtQPPQsE
P35580 S1965 PSP MYH10 QLHLEGAsLELsDDDtEsKtsDVNEtQPPQsE_________
P35580 S1975 PSP MYH10 LsDDDtEsKtsDVNEtQPPQsE___________________
P35580 T1960 PSP MYH10 RSGRRQLHLEGAsLELsDDDtEsKtsDVNEtQPPQsE____
P35638 S14 GPS6|SIGNOR|ELM|iPTMNet|PSP DDIT3 CHOP CHOP10 GADD153 _______MAAESLPFSFGTLssWELEAWYEDLQEVLssDEN
P35638 S15 GPS6|SIGNOR|ELM|iPTMNet|PSP DDIT3 CHOP CHOP10 GADD153 ______MAAESLPFSFGTLssWELEAWYEDLQEVLssDENG
P35638 S30 SIGNOR|ELM|iPTMNet|PSP DDIT3 CHOP CHOP10 GADD153 FGTLssWELEAWYEDLQEVLssDENGGTYVSPPGNEEEESK
P35638 S31 GPS6|SIGNOR|ELM|iPTMNet|PSP DDIT3 CHOP CHOP10 GADD153 GTLssWELEAWYEDLQEVLssDENGGTYVSPPGNEEEESKI
P35659 S32 SIGNOR DEK GtPtQPAsEKEPEMPGPREEsEEEEDEDDEEEEEEEKEKsL
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36955 S114 PSP SERPINF1 PEDF PIG35 LGAEQRTESIIHRALYYDLIsSPDIHGTYKELLDTVTAPQK
P36955 S24 PSP SERPINF1 PEDF PIG35 LVLLLCIGALLGHSSCQNPAsPPEEGSPDPDSTGALVEEED
P37840 S129 GPS6|SIGNOR|ELM|iPTMNet|PSP SNCA NACP PARK1 QEGILEDMPVDPDNEAyEMPsEEGyQDyEPEA_________
P37840 S87 SIGNOR SNCA NACP PARK1 GGAVVTGVTAVAQKTVEGAGsIAAATGFVKKDQLGKNEEGA
P38398 S1572 SIGNOR|PSP BRCA1 RNF53 yLPRQDLEGTPYLESGISLFsDDPEsDPSEDRAPESARVGN
P39687 S158 ELM|PSP ANP32A C15orf1 LANP MAPM PHAP1 LLPQLtyLDGyDRDDKEAPDsDAEGYVEGLDDEEEDEDEEE
P39687 S204 ELM|PSP ANP32A C15orf1 LANP MAPM PHAP1 QVVEDEEDEDEEEEGEEEDVsGEEEEDEEGYNDGEVDDEED
P40337 S33 GPS6|PSP VHL VGAEEAGVEEYGPEEDGGEEsGAEEsGPEEsGPEELGAEEE
P40337 S38 GPS6|PSP VHL AGVEEYGPEEDGGEEsGAEEsGPEEsGPEELGAEEEMEAGR
P40337 S43 GPS6|PSP VHL YGPEEDGGEEsGAEEsGPEEsGPEELGAEEEMEAGRPRPVL
P40692 S477 PSP MLH1 COCA2 EMSEKRGPTSSNPRKRHREDsDVEMVEDDSRKEMTAACTPR
P41002 S621 SIGNOR|PSP CCNF FBX1 FBXO1 LGSFLDWSLDCCSGYEGDQEsEGEKEGDVTAPSGILDVTVV
P41208 S158 PSP CETN2 CALT CEN2 tDEELQEMIDEADRDGDGEVsEQEFLRIMKKTsLY______
P41208 T138 PSP CETN2 CALT CEN2 tGKISFKNLKRVAKELGENLtDEELQEMIDEADRDGDGEVs
P41236 S121 SIGNOR|ELM|iPTMNet|PSP|Sugiyama PPP1R2 IPP2 ARKLAAAEGLEPKyRIQEQEssGEEDsDLsPEEREKKRQFE
P41236 S122 SIGNOR|ELM|iPTMNet|PSP PPP1R2 IPP2 RKLAAAEGLEPKyRIQEQEssGEEDsDLsPEEREKKRQFEM
P41236 S87 SIGNOR|ELM|iPTMNet|PSP PPP1R2 IPP2 KIDEPstPYHsMMGDDEDACsDtEAtEAMAPDILARKLAAA
P42166 S67 Sugiyama TMPO LAP2 ARNRPPLPAGTNsKGPPDFssDEEREPtPVLGsGAAAAGRS
P42167 S67 Sugiyama TMPO LAP2 ARNRPPLPAGTNSKGPPDFssDEEREPtPVLGsGAAAAGRS
P42224 S727 PSP STAT1 IsVsEVHPSRLQttDNLLPMsPEEFDEVSRIVGsVEFDSMM
P42575 S157 SIGNOR|PSP CASP2 ICH1 NEDD2 DLsLPFPVCESCPLYKKLRLstDtVEHsLDNKDGPVCLQVK
P42768 S483 SIGNOR|iPTMNet|PSP WAS IMD2 SEGLVGALMHVMQKRSRAIHssDEGEDQAGDEDEDDEWDD_
P42768 S484 GPS6|SIGNOR|ELM|iPTMNet|PSP WAS IMD2 EGLVGALMHVMQKRSRAIHssDEGEDQAGDEDEDDEWDD__
P42858 S13 PSP HTT HD IT15 ________MAtLEKLMKAFEsLKsFQQQQQQQQQQQQQQQQ
P42858 S16 PSP HTT HD IT15 _____MAtLEKLMKAFEsLKsFQQQQQQQQQQQQQQQQQQQ
P43629 S385 SIGNOR|PSP KIR3DL1 CD158E NKAT3 NKB1 SNKKNAAVMDQEPAGNRTANsEDsDEQDPEEVTYAQLDHCV
P43629 S388 SIGNOR|PSP KIR3DL1 CD158E NKAT3 NKB1 KNAAVMDQEPAGNRTANsEDsDEQDPEEVTYAQLDHCVFTQ
P45973 S11 SIGNOR CBX5 HP1A __________MGKKTKRtADssssEDEEEyVVEKVLDRRVV
P45973 S12 SIGNOR CBX5 HP1A _________MGKKTKRtADssssEDEEEyVVEKVLDRRVVK
P45973 S13 SIGNOR CBX5 HP1A ________MGKKTKRtADssssEDEEEyVVEKVLDRRVVKG
P45973 S14 SIGNOR CBX5 HP1A _______MGKKTKRtADssssEDEEEyVVEKVLDRRVVKGQ
P45984 S407 GPS6|SIGNOR|ELM|PSP MAPK9 JNK2 PRKM9 SAPK1A PSQSSSINDISSMSTEQtLAsDTDSSLDASTGPLEGCR___
P45984 T404 GPS6|SIGNOR|ELM|PSP MAPK9 JNK2 PRKM9 SAPK1A NATPSQSSSINDISSMSTEQtLAsDTDSSLDASTGPLEGCR
P46060 S358 SIGNOR|iPTMNet|PSP RANGAP1 KIAA1835 SD CEQLQEVLEGFNMAKVLASLsDDEDEEEEEEGEEEEEEAEE
P46527 S83 PSP CDKN1B KIP1 p27 DFQNHKPLEGKyEWQEVEKGsLPEFyyRPPRPPKGACKVPA
P46531 S1900 GPS6|PSP NOTCH1 TAN1 DGFTPLMIASCSGGGLEtGNsEEEEDAPAVISDFIYQGASL
P46531 T1897 GPS6 NOTCH1 TAN1 RGPDGFTPLMIASCSGGGLEtGNsEEEEDAPAVISDFIYQG
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P48426 S304 GPS6|SIGNOR|ELM|PSP PIP4K2A PI5P4KA PIP5K2 PIP5K2A ERAEQEEVECEENDGEEEGEsDGTHPVGTPPDSPGNTLNSS
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P49321 S497 SIGNOR NASP tEGsEEDDKENDKtEEMPNDsVLENKsLQENEEEEIGNLEL
P49368 S252 Sugiyama CCT3 CCTG TRIC5 YIKNPRIVLLDssLEyKKGEsQtDIEITREEDFTRILQMEE
P49418 T350 SIGNOR|PSP AMPH AMPH1 PEISVTTPSQNEVPEVKKEEtLLDLDFDPFKPEVTPAGSAG
P49418 T387 SIGNOR|PSP AMPH AMPH1 GSAGVTHSPMSQTLPWDLWTtSTDLVQPASGGSFNGFTQPQ
P49427 S203 SIGNOR|ELM|PSP CDC34 UBCH3 UBE2R1 VPTTLAEYCVKTKAPAPDEGsDLFYDDYYEDGEVEEEADsC
P49427 S222 SIGNOR|ELM|PSP CDC34 UBCH3 UBE2R1 GsDLFYDDYYEDGEVEEEADsCFGDDEDDsGtEEs______
P49427 S231 GPS6|SIGNOR|ELM|PSP CDC34 UBCH3 UBE2R1 YEDGEVEEEADsCFGDDEDDsGtEEs_______________
P49427 S236 SIGNOR|ELM|PSP CDC34 UBCH3 UBE2R1 VEEEADsCFGDDEDDsGtEEs____________________
P49427 T233 SIGNOR|ELM|PSP CDC34 UBCH3 UBE2R1 DGEVEEEADsCFGDDEDDsGtEEs_________________
P49716 S57 SIGNOR|PSP CEBPD AEPGALGEPGAAAPAMYDDEsAIDFSAYIDSMAAVPTLELC
P49736 S108 PSP MCM2 BM28 CCNL1 CDCL1 KIAA0030 DAYEAEGLALDDEDVEELtAsQREAAERAMRQRDREAGRGL
P49736 S13 SIGNOR|PSP MCM2 BM28 CCNL1 CDCL1 KIAA0030 ________MAEssEsFtMAssPAQRRRGNDPLtssPGRssR
P49736 S139 PSP|Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 QRDREAGRGLGRMRRGLLyDsDEEDEERPARKRRQVERAtE
P49736 S27 PSP MCM2 BM28 CCNL1 CDCL1 KIAA0030 sFtMAssPAQRRRGNDPLtssPGRssRRtDALtssPGRDLP
P49736 S40 PSP MCM2 BM28 CCNL1 CDCL1 KIAA0030 GNDPLtssPGRssRRtDALtssPGRDLPPFEDEsEGLLGtE
P49736 S41 PSP MCM2 BM28 CCNL1 CDCL1 KIAA0030 NDPLtssPGRssRRtDALtssPGRDLPPFEDEsEGLLGtEG
P49736 S53 PSP MCM2 BM28 CCNL1 CDCL1 KIAA0030 RRtDALtssPGRDLPPFEDEsEGLLGtEGPLEEEEDGEELI
P49736 T457 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 TVILANHVAKKDNKVAVGELtDEDVKMITSLSKDQQIGEKI
P49795 S151 ELM RGS19 GAIP GNAI3IP NQHVVDEKARLIyEDyVSILsPKEVSLDSRVREGINKKMQE
P49795 S24 SIGNOR|ELM|iPTMNet|PSP RGS19 GAIP GNAI3IP PHEAEKQITGPEEADRPPsMssHDTASPAAPSRNPCCLCWC
P49810 S19 SIGNOR|ELM|iPTMNet PSEN2 AD4 PS2 PSNL2 STM2 __MLTFMAsDsEEEVCDERtsLMsAEsPtPRSCQEGRQGPE
P49810 S327 SIGNOR PSEN2 AD4 PS2 PSNL2 STM2 LDPSSQGALQLPYDPEMEEDsYDsFGEPsYPEVFEPPLTGY
P49810 S330 GPS6|SIGNOR|ELM|iPTMNet|PSP PSEN2 AD4 PS2 PSNL2 STM2 SSQGALQLPYDPEMEEDsYDsFGEPsYPEVFEPPLTGYPGE
P49810 S335 GPS6|SIGNOR|ELM|iPTMNet|PSP PSEN2 AD4 PS2 PSNL2 STM2 LQLPYDPEMEEDsYDsFGEPsYPEVFEPPLTGYPGEELEEE
P49810 S7 GPS6|SIGNOR|ELM|iPTMNet|PSP PSEN2 AD4 PS2 PSNL2 STM2 ______________MLTFMAsDsEEEVCDERtsLMsAEsPt
P49810 S9 GPS6|SIGNOR|ELM|iPTMNet|PSP PSEN2 AD4 PS2 PSNL2 STM2 ____________MLTFMAsDsEEEVCDERtsLMsAEsPtPR
P49959 S558 SIGNOR|PSP MRE11 HNGS1 MRE11A SAFSADDLMSIDLAEQMANDsDDsISAATNKGRGRGRGRRG
P49959 S561 SIGNOR|PSP MRE11 HNGS1 MRE11A SADDLMSIDLAEQMANDsDDsISAATNKGRGRGRGRRGGRG
P49959 S649 GPS6|PSP MRE11 HNGS1 MRE11A QQPSRNVTTKNYsEVIEVDEsDVEEDIFPTTSKTDQRWSST
P49959 S688 SIGNOR|PSP MRE11 HNGS1 MRE11A STSSSKIMsQsQVsKGVDFEssEDDDDDPFMNTSSLRRNRR
P49959 S689 SIGNOR|PSP MRE11 HNGS1 MRE11A TSSSKIMsQsQVsKGVDFEssEDDDDDPFMNTSSLRRNRR_
P50895 S598 PSP BCAM LU MSK19 CCRQRREKGAPPPGEPGLsHsGsEQPEQtGLLMGGAsGGAR
P51116 S410 Sugiyama FXR2 FMR1L2 LGFRPPGsGRGsGGsDKAGystDEssSSsLHATRTYGGSYG
P51116 T411 Sugiyama FXR2 FMR1L2 GFRPPGsGRGsGGsDKAGystDEssSSsLHATRTYGGSYGG
P51580 S14 Sugiyama TPMT _______MDGTRTSLDIEEysDtEVQKNQVLTLEEWQDKWV
P51580 T16 Sugiyama TPMT _____MDGTRTSLDIEEysDtEVQKNQVLTLEEWQDKWVNG
P51636 S23 SIGNOR|PSP CAV2 LETEKADVQLFMDDDsysHHsGLEyADPEKFADsDQDRDPH
P51636 S36 SIGNOR|PSP CAV2 DDsysHHsGLEyADPEKFADsDQDRDPHRLNSHLKLGFEDV
P51811 S383 ELM XK XKR1 XRG1 ILFMLVFYQFFHPCKKLFSSsVSEGFQRWLRCFCWACRQQK
P51858 S133 Sugiyama HDGF HMG1L2 EPEPEAAEGDGDKKGNAEGssDEEGKLVIDEPAKEKNEKGA
P51946 T315 ELM|PSP CCNH KGYEDDDYVsKKSKHEEEEWtDDDLVEsL____________
P52597 S63 Sugiyama HNRNPF HNRPF VHFIYTREGRQsGEAFVELGsEDDVKMALKKDRESMGHRyI
P52655 S280 SIGNOR|ELM GTF2A1 TF2A1 AQPAQTQAPLVLQVDGTGDTssEEDEDEEEDYDDDEEEDKE
P52655 S281 SIGNOR|ELM GTF2A1 TF2A1 QPAQTQAPLVLQVDGTGDTssEEDEDEEEDYDDDEEEDKEK
P52655 S316 SIGNOR|ELM GTF2A1 TF2A1 EEDKEKDGAEDGQVEEEPLNsEDDVsDEEGQELFDTENVVV
P52655 S321 SIGNOR|ELM GTF2A1 TF2A1 KDGAEDGQVEEEPLNsEDDVsDEEGQELFDTENVVVCQYDK
P52907 S9 SIGNOR|PSP CAPZA1 ____________MADFDDRVsDEEKVRIAAKFITHAPPGEF
P52952 S164 SIGNOR|iPTMNet NKX2-5 CSX NKX2.5 NKX2E LFSQAQVYELERRFKQQRYLsAPERDQLASVLKLTSTQVKI
P53539 S27 SIGNOR|PSP FOSB G0S3 GDYDSGSRCSSSPSAESQYLsSVDSFGSPPTAAASQECAGL
P53999 S10 iPTMNet SUB1 PC4 RPO2TC1 ___________MPKSKELVsssssGsDsDsEVDKKLKRKKQ
P53999 S11 ELM SUB1 PC4 RPO2TC1 __________MPKSKELVsssssGsDsDsEVDKKLKRKKQV
P53999 S118 Sugiyama SUB1 PC4 RPO2TC1 PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________
P53999 S12 iPTMNet SUB1 PC4 RPO2TC1 _________MPKSKELVsssssGsDsDsEVDKKLKRKKQVA
P53999 S13 ELM|iPTMNet SUB1 PC4 RPO2TC1 ________MPKSKELVsssssGsDsDsEVDKKLKRKKQVAP
P53999 S15 ELM|iPTMNet SUB1 PC4 RPO2TC1 ______MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEK
P53999 S17 ELM|iPTMNet|Sugiyama SUB1 PC4 RPO2TC1 ____MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPV
P53999 S19 ELM|iPTMNet SUB1 PC4 RPO2TC1 __MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPVKK
P53999 S9 iPTMNet SUB1 PC4 RPO2TC1 ____________MPKSKELVsssssGsDsDsEVDKKLKRKK
P54105 S102 Sugiyama CLNS1A CLCI ICLN VNAKFEEEsKEPVADEEEEDsDDDVEPITEFRFVPSDKSAL
P54252 S236 SIGNOR|PSP ATXN3 ATX3 MJD MJD1 SCA3 NDGSGMLDEDEEDLQRALALsRQEIDMEDEEADLRRAIQLs
P54252 S335 SIGNOR|PSP ATXN3 ATX3 MJD MJD1 SCA3 PCERPATSSGALGSDLGDAMsEEDMLQAAVTMsLETVRNDL
P54252 S347 SIGNOR|PSP ATXN3 ATX3 MJD MJD1 SCA3 GSDLGDAMsEEDMLQAAVTMsLETVRNDLKTEGKK______
P54274 T122 SIGNOR|PSP TERF1 PIN2 TRBF1 TRF TRF1 RNSAEAIIHGLSsLTACQLRtIYICQFLTRIAAGKTLDAQF
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P54845 S117 PSP NRL D14S46E ELLQGQGPVPVDGPHGYYPGsPEETGAQHVQLAERFSDAAL
P55010 S174 SIGNOR|iPTMNet EIF5 GKKEKEKKNRKGKDKENGSVsSSETPPPPPPPNEINPPPHT
P55010 S389 GPS6|SIGNOR|ELM|iPTMNet|PSP EIF5 KEIRVKAEPFIKWLKEAEEEssGGEEEDEDENIEVVySKAA
P55010 S390 GPS6|SIGNOR|ELM|iPTMNet|PSP EIF5 EIRVKAEPFIKWLKEAEEEssGGEEEDEDENIEVVySKAAs
P55010 T207 PSP EIF5 EINPPPHTMEEEEDDDWGEDttEEAQRRRMDEISDHAKVLt
P55010 T208 PSP EIF5 INPPPHTMEEEEDDDWGEDttEEAQRRRMDEISDHAKVLtL
P55042 S214 SIGNOR|ELM|iPTMNet|PSP RRAD RAD DDVPIILVGNKSDLVRSREVsVDEGRACAVVFDCKFIETSA
P55042 S257 SIGNOR|iPTMNet|PSP RRAD RAD HHNVQALFEGVVRQIRLRRDsKEANARRQAGTRRREsLGKK
P55042 S273 SIGNOR|iPTMNet|PSP RRAD RAD LRRDsKEANARRQAGTRRREsLGKKAKRFLGRIVARNsRKM
P55042 S290 SIGNOR|iPTMNet|PSP RRAD RAD RREsLGKKAKRFLGRIVARNsRKMAFRAKsKsCHDLSVL__
P55042 S299 SIGNOR|PSP RRAD RAD KRFLGRIVARNsRKMAFRAKsKsCHDLSVL___________
P55087 S276 SIGNOR|ELM AQP4 VEFKRRFKEAFSKAAQQTKGsYMEVEDNRsQVETDDLILKP
P55087 S285 SIGNOR|ELM AQP4 AFSKAAQQTKGsYMEVEDNRsQVETDDLILKPGVVHVIDVD
P55087 S316 SIGNOR|ELM AQP4 PGVVHVIDVDRGEEKKGKDQsGEVLssV_____________
P55957 S64 SIGNOR|ELM|iPTMNet BID LPVLAPQWEGyDELQtDGNRssHsRLGRIEADsEsQEDIIR
P55957 T59 SIGNOR|ELM|iPTMNet BID ALGHELPVLAPQWEGyDELQtDGNRssHsRLGRIEADsEsQ
P56270 S460 SIGNOR|iPTMNet|PSP MAZ ZNF801 AAAAAAAAAVAAPPTAVGSLsGAEGVPVSsQPLPSQPW___
P56270 S469 ELM MAZ ZNF801 VAAPPTAVGSLsGAEGVPVSsQPLPSQPW____________
P60484 S370 GPS6|SIGNOR|ELM|iPTMNet|PSP PTEN MMAC1 TEP1 TVEEPSNPEASSsTSVtPDVsDNEPDHyRYsDttDsDPENE
P60484 S380 GPS6|SIGNOR|ELM|PSP PTEN MMAC1 TEP1 SSsTSVtPDVsDNEPDHyRYsDttDsDPENEPFDEDQHtQI
P60484 S385 GPS6|SIGNOR|ELM|PSP PTEN MMAC1 TEP1 VtPDVsDNEPDHyRYsDttDsDPENEPFDEDQHtQItKV__
P60484 T366 SIGNOR|iPTMNet PTEN MMAC1 TEP1 YFTKTVEEPSNPEASSsTSVtPDVsDNEPDHyRYsDttDsD
P60484 T382 GPS6|SIGNOR|ELM|PSP PTEN MMAC1 TEP1 sTSVtPDVsDNEPDHyRYsDttDsDPENEPFDEDQHtQItK
P60484 T383 SIGNOR|PSP PTEN MMAC1 TEP1 TSVtPDVsDNEPDHyRYsDttDsDPENEPFDEDQHtQItKV
P60983 S53 GPS6|SIGNOR|ELM|iPTMNet|PSP GMFB IMKIDKDKRLVVLDEELEGIsPDELKDELPERQPRFIVYsY
P61218 S2 ELM POLR2F POLRF ___________________MsDNEDNFDGDDFDDVEEDEGL
P61244 S11 GPS6|SIGNOR|ELM|PSP MAX BHLHD4 __________MsDNDDIEVEsDEEQPRFQSAADKRAHHNAL
P61244 S129 iPTMNet MAX BHLHD4 AQLQTNYPssDNsLYTNAKGsTIsAFDGGSDsSSEsEPEEP
P61244 S132 iPTMNet MAX BHLHD4 QTNYPssDNsLYTNAKGsTIsAFDGGSDsSSEsEPEEPQSR
P61244 S2 GPS6|SIGNOR|ELM|iPTMNet|PSP MAX BHLHD4 ___________________MsDNDDIEVEsDEEQPRFQSAA
P62269 T60 Sugiyama RPS18 D6S218E YAHVVLRKADIDLTKRAGELtEDEVERVItIMQNPRQYKIP
P67870 S2 ELM|PSP CSNK2B CK2N G5A ___________________MsssEEVSWISWFCGLRGNEFF
P67870 S3 ELM|PSP CSNK2B CK2N G5A __________________MsssEEVSWISWFCGLRGNEFFC
P68400 Y182 PSP CSNK2A1 CK2A1 VMIDHEHRKLRLIDWGLAEFyHPGQEYNVRVASRYFKGPEL
P78344 S902 SIGNOR|PSP EIF4G2 DAP5 OK/SW-cl.75 KALFQVNQWLTWLEtAEEEEsEEEAD_______________
P83916 T51 SIGNOR|PSP CBX1 CBX VVKGKVEYLLKWKGFSDEDNtWEPEENLDCPDLIAEFLQSQ
P84090 S24 iPTMNet ERH TILLVQPTKRPEGRtyADyEsVNECMEGVCKMYEEHLKRMN
P84090 T18 iPTMNet ERH ___MsHTILLVQPTKRPEGRtyADyEsVNECMEGVCKMYEE
Q00266 S114 PSP MAT1A AMS1 MATA1 DSAKGFDFKTCNVLVALEQQsPDIAQCVHLDRNEEDVGAGD
Q00613 T142 GPS6|SIGNOR|ELM|iPTMNet HSF1 HSTF1 VSTLKSEDIKIRQDSVTKLLtDVQLMKGKQECMDSKLLAMK
Q00987 S260 PSP MDM2 sVsDQFsVEFEVEsLDsEDYsLsEEGQELsDEDDEVyQVtV
Q00987 S269 PSP MDM2 FEVEsLDsEDYsLsEEGQELsDEDDEVyQVtVyQAGESDTD
Q01082 S2110 SIGNOR|iPTMNet|PSP SPTBN1 SPTB2 QQEEEERKRRPPsPEPstKVsEEAEsQQQWDtsKGEQVsQN
Q01082 T2159 SIGNOR|iPTMNet|PSP SPTBN1 SPTB2 PRMAETVDTsEMVNGAtEQRtssKEssPIPsPtsDRKAKTA
Q01534 T300 SIGNOR|iPTMNet|PSP TSPY1 TSPY LWRNPLQYYKRMKPPEEGTEtSGDSQLLS____________
Q01831 S129 PSP XPC XPCC AHHLKRGATMNEDSNEEEEEsENDWEEVEELSEPVLGDVRE
Q01831 S94 SIGNOR|PSP XPC XPCC KVAKVTVKSENLKVIKDEALsDGDDLRDFPsDLKKAHHLKR
Q01892 S129 SIGNOR|ELM|iPTMNet SPIB NFASQTLVPPAYAPYPSPVLsEEEDLPLDSPALEVsDsESD
Q01892 S144 SIGNOR|ELM|iPTMNet SPIB PSPVLsEEEDLPLDSPALEVsDsESDEALVAGPEGKGSEAG
Q01892 S146 SIGNOR|ELM|iPTMNet SPIB PVLsEEEDLPLDSPALEVsDsESDEALVAGPEGKGSEAGTR
Q01892 S37 SIGNOR|ELM|iPTMNet SPIB LYPDGVFYDLDSCKHSSYPDsEGAPDSLWDWTVAPPVPAtP
Q02078 S289 GPS6|ELM|PSP MEF2A MEF2 RKPDLRVVIPPSSKGMMPPLsEEEELELNTQRISSSQATQP
Q02790 T143 SIGNOR|iPTMNet FKBP4 FKBP52 PPNATLVFEVELFEFKGEDLtEEEDGGIIRRIQTRGEGYAK
Q02952 S598 Sugiyama AKAP12 AKAP250 CLEKGLAEVQQDGEAEEGAtsDGEKKREGVtPWAsFKKMVt
Q03014 S163 PSP HHEX HEX PRH PRHX RFSNDQTIELEKKFETQKYLsPPERKRLAKMLQLsERQVKT
Q03014 S177 PSP HHEX HEX PRH PRHX ETQKYLsPPERKRLAKMLQLsERQVKTWFQNRRAKWRRLKQ
Q03112 S1037 SIGNOR MECOM EVI1 MDS1 PRDM3 DKEDAYFTEIRNFIGNSNHGsQsPRNVEERMNGSHFKDEKA
Q03112 S726 SIGNOR MECOM EVI1 MDS1 PRDM3 SMYPFPDRDLRSLPLKMEPQsPGEVKKLQKGSSESPFDLTT
Q03135 S88 SIGNOR|ELM|iPTMNet CAV1 CAV FEDVIAEPEGTHsFDGIWKAsFTTFTVTKYWFYRLLSALFG
Q04206 S529 GPS6|SIGNOR|ELM|PSP RELA NFKB3 RPPDPAPAPLGAPGLPNGLLsGDEDFSsIADMDFsALLSQI
Q04206 S543 SIGNOR|iPTMNet RELA NFKB3 LPNGLLsGDEDFSsIADMDFsALLSQISS____________
Q04724 S239 GPS6|SIGNOR|ELM|PSP TLE1 EFSNDIKKRKVDDKDSSHYDsDGDKsDDNLVVDVsNEDPss
Q04724 S253 SIGNOR|PSP TLE1 DSSHYDsDGDKsDDNLVVDVsNEDPssPRAsPAHsPRENGI
Q05940 S511 SIGNOR|ELM|iPTMNet SLC18A2 SVMT VMAT2 KTKMYTQNNIQSYPIGEDEEsEsD_________________
Q05940 S513 SIGNOR|ELM SLC18A2 SVMT VMAT2 KMYTQNNIQSYPIGEDEEsEsD___________________
Q06265 S392 SIGNOR|PSP EXOSC9 PMSCL1 KMDTGVEVsDIGsQDAPIILsDsEEEEMIILEPDKNPKKIR
Q06265 S394 SIGNOR|PSP EXOSC9 PMSCL1 DTGVEVsDIGsQDAPIILsDsEEEEMIILEPDKNPKKIRTQ
Q06413 S59 SIGNOR|ELM MEF2C CDCEIALIIFNSTNKLFQYAsTDMDKVLLKYTEYNEPHESR
Q06609 T13 PSP RAD51 RAD51A RECA ________MAMQMQLEANADtsVEEESFGPQPISRLEQCGI
Q06787 S500 PSP FMR1 GHGRRGPGYTSGTNSEAsNAsEtEsDHRDELsDWSLAPTEE
Q08945 S510 GPS6|SIGNOR|ELM|iPTMNet|PSP SSRP1 FACT80 DVAEEFDSNASASSSSNEGDsDRDEKKRKQLKKAKMAKDRK
Q08945 S657 SIGNOR|iPTMNet|PSP SSRP1 FACT80 MEKKSTPSRGsSSKSsSRQLsEsFKSKEFVssDEsssGENK
Q08945 S688 GPS6|SIGNOR|ELM|iPTMNet|PSP SSRP1 FACT80 sDEsssGENKSKKKRRRSEDsEEEELASTPPSSEDSASGSD
Q12798 T138 PSP CETN1 CEN1 CETN TGKISFKNLKRVANELGENLtDEELQEMIDEADRDGDGEVN
Q12913 T1318 SIGNOR PTPRJ DEP1 IVRSQKDsKVDLIyQNttAMtIyENLAPVTTFGKTNGYIA_
Q12972 S204 SIGNOR|ELM PPP1R8 ARD1 NIPP1 EGNLDIQRPKRKRKNsRVtFsEDDEIINPEDVDPSVGRFRN
Q12972 T161 SIGNOR|ELM PPP1R8 ARD1 NIPP1 EKMGGEDDELKGLLGLPEEEtELDNLTEFNTAHNKRIsTLT
Q13085 S29 SIGNOR|ELM ACACA ACAC ACC1 ACCA QPLELNQHSRFIIGsVsEDNsEDEISNLVKLDLLEEKEGsL
Q13133 S198 SIGNOR|PSP NR1H3 LXRA KLKRQEEEQAHATSLPPRAssPPQILPQLSPEQLGMIEKLV
Q13144 S717 SIGNOR|iPTMNet EIF2B5 EIF2BE LRKNQQLQRFIQWLKEAEEEssEDD________________
Q13144 S718 SIGNOR|iPTMNet EIF2B5 EIF2BE RKNQQLQRFIQWLKEAEEEssEDD_________________
Q13148 S379 PSP TARDBP TDP43 MQREPNQAFGsGNNSYsGsNsGAAIGWGsAsNAGsGsGFNG
Q13148 S409 PSP TARDBP TDP43 sNAGsGsGFNGGFGssMDsKssGWGM_______________
Q13148 S410 PSP TARDBP TDP43 NAGsGsGFNGGFGssMDsKssGWGM________________
Q13153 S223 PSP PAK1 RsVIEPLPVtPtRDVAtsPIsPtENNttPPDALtRNTEKQK
Q13224 S1479 SIGNOR GRIN2B NMDAR2B NKNPRAFNGSSNGHVyEKLSsIESDV_______________
Q13283 S149 SIGNOR|PSP G3BP1 G3BP DIFRyQDEVFGGFVtEPQEEsEEEVEEPEERQQtPEVVPDD
Q13323 S35 GPS6|ELM|PSP BIK NBK TLLYEQLLEPPTMEVLGMtDsEEDLDPMEDFDSLECMEGSD
Q13323 T33 PSP BIK NBK METLLYEQLLEPPTMEVLGMtDsEEDLDPMEDFDSLECMEG
Q13347 S302 Sugiyama EIF3I EIF3S2 TRIP1 KGHFGPINSVAFHPDGKSYssGGEDGyVRIHYFDPQYFEFE
Q13351 T23 SIGNOR|ELM KLF1 EKLF TAETALPSISTLTALGPFPDtQDDFLKWWRSEEAQDMGPGP
Q13371 S18 SIGNOR|PSP PDCL PHLOP1 PhLP1 ___MTTLDDKLLGEKLQyyysssEDEDsDHEDKDRGRCAPA
Q13371 S19 SIGNOR|PSP PDCL PHLOP1 PhLP1 __MTTLDDKLLGEKLQyyysssEDEDsDHEDKDRGRCAPAs
Q13371 S20 SIGNOR|PSP PDCL PHLOP1 PhLP1 _MTTLDDKLLGEKLQyyysssEDEDsDHEDKDRGRCAPAss
Q13371 S25 SIGNOR|PSP PDCL PHLOP1 PhLP1 DDKLLGEKLQyyysssEDEDsDHEDKDRGRCAPAsssVPAE
Q13371 S296 PSP PDCL PHLOP1 PhLP1 EKEVLVLTSVRNsAtCHsEDsDLEID_______________
Q13393 S610 PSP PLD1 YRSHHNLIHGLKPHFKLFHPssESEQGLTRPHADtGsIRsL
Q13393 S611 PSP PLD1 RSHHNLIHGLKPHFKLFHPssESEQGLTRPHADtGsIRsLQ
Q13422 S101 SIGNOR IKZF1 IK1 IKAROS LYF1 ZNFN1A1 DLRMLDASGEKMNGSHRDQGsSALSGVGGIRLPNGKLKCDI
Q13422 S13 SIGNOR IKZF1 IK1 IKAROS LYF1 ZNFN1A1 ________MDADEGQDMSQVsGKESPPVSDtPDEGDEPMPI
Q13422 S295 SIGNOR IKZF1 IK1 IKAROS LYF1 ZNFN1A1 KSSMPQKFLGDKGLsDtPYDssAsYEKENEMMKSHVMDQAI
Q13422 S63 SIGNOR IKZF1 IK1 IKAROS LYF1 ZNFN1A1 GQQSSKSDRVVASNVKVETQsDEENGRACEMNGEECAEDLR
Q13422 T23 SIGNOR IKZF1 IK1 IKAROS LYF1 ZNFN1A1 ADEGQDMSQVsGKESPPVSDtPDEGDEPMPIPEDLSTTSGG
Q13426 T233 PSP XRCC4 GETAICSEMTADRDPVYDEstDEEsENQTDLSGLASAAVSK
Q13428 S279 Sugiyama TCOF1 PAKRAKKPEEEsEssEEGsEsEEEAPAGTRSQVKASEKILQ
Q13428 T210 SIGNOR|PSP TCOF1 MVSAGQADSSSEDTSSSSDEtDVEGKPSVKPAQVKAssVst
Q13442 S57 Sugiyama PDAP1 HASPP28 EEEQKEGGDGAAGDPKKEKKsLDsDEsEDEEDDyQQKRKGV
Q13442 S60 Sugiyama PDAP1 HASPP28 QKEGGDGAAGDPKKEKKsLDsDEsEDEEDDyQQKRKGVEGL
Q13442 S63 Sugiyama PDAP1 HASPP28 GGDGAAGDPKKEKKsLDsDEsEDEEDDyQQKRKGVEGLIDI
Q13501 S403 PSP SQSTM1 ORCA OSIL yPHLPPEADPRLIESLsQMLsMGFsDEGGWLTRLLQTKNyD
Q13509 S444 PSP TUBB3 TUBB4 QYQDATAEEEGEMYEDDEEEsEAQGPK______________
Q13530 S380 SIGNOR|PSP SERINC3 DIFF33 TDE1 SBBI99 QVDKLtLsGsDsVILGDtttsGAsDEEDGQPRRAVDNEKEG
Q13530 S383 SIGNOR|PSP SERINC3 DIFF33 TDE1 SBBI99 KLtLsGsDsVILGDtttsGAsDEEDGQPRRAVDNEKEGVQY
Q13541 S112 SIGNOR|iPTMNet|PSP|Sugiyama EIF4EBP1 EAsQsHLRNsPEDKRAGGEEsQFEMDI______________
Q13547 S421 GPS6|SIGNOR|ELM|iPTMNet|PSP HDAC1 RPD3L1 PDKRIsICssDKRIACEEEFsDsEEEGEGGRKNsSNFKKAK
Q13547 S423 GPS6|SIGNOR|ELM|iPTMNet|PSP HDAC1 RPD3L1 KRIsICssDKRIACEEEFsDsEEEGEGGRKNsSNFKKAKRV
Q13563 S812 GPS6|SIGNOR|ELM|PSP PKD2 TRPP1 TRPP2 DHssLPRPMssRSFPRSLDDsEEDDDEDSGHSSRRRGsIss
Q13610 S50 Sugiyama PWP1 EEVKRLIAEAKEKLQEEGGGsDEEEtGsPsEDGMQsARTQA
Q13698 S1575 SIGNOR CACNA1S CACH1 CACN1 CACNL1A3 IQAGLRTIEEEAAPEICRtVsGDLAAEEELERAMVEAAMEE
Q13829 S278 PSP TNFAIP1 BACURD2 EDP1 TPRVPDNsLLEATSRSRSQAsPsEDEETFELRDRVRRIHVK
Q13829 S280 SIGNOR|PSP TNFAIP1 BACURD2 EDP1 RVPDNsLLEATSRSRSQAsPsEDEETFELRDRVRRIHVKRY
Q14005 S743 SIGNOR|iPTMNet|PSP IL16 NLFSPIMSENHGHMPLQPNAsLNEEEGTQGHPDGtPPKLDT
Q14204 S1313 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 DREKCAKAKEALELtDtGLLsGSEERVQVALEELQDLKGVW
Q14432 S408 Sugiyama PDE3A QAIHKPRVNPVtsLsENytCsDsEESSEKDKLAIPKRLRRs
Q14449 S358 PSP GRB14 RLLKYGMQLYQNYMHPYQGRsGCSsQSIsPMRsIsENSLVA
Q14449 S362 PSP GRB14 YGMQLYQNYMHPYQGRsGCSsQSIsPMRsIsENSLVAMDFS
Q14449 S366 PSP GRB14 LYQNYMHPYQGRsGCSsQSIsPMRsIsENSLVAMDFSGQKS
Q14449 S370 PSP GRB14 YMHPYQGRsGCSsQSIsPMRsIsENSLVAMDFSGQKSRVIE
Q14493 T61 SIGNOR|PSP SLBP HBP RPEDAEEAEHRGAERRPEsFttPEGPKPRSRCSDWASAVEE
Q14566 S758 Sugiyama MCM6 EDESALKRSELVNWYLKEIEsEIDsEEELINKKRIIEKVIH
Q14566 S762 Sugiyama MCM6 ALKRSELVNWYLKEIEsEIDsEEELINKKRIIEKVIHRLTH
Q14676 S218 PSP MDC1 KIAA0170 NFBD1 EEGHSPVLGGLGPPFAFNLNsDtDVEEGQQPATEEASSAAR
Q14676 S299 SIGNOR|PSP MDC1 KIAA0170 NFBD1 GNGVVPAGVILERsQPPGEDsDtDVDDDsRPPGRPAEVHLE
Q14676 S329 PSP MDC1 KIAA0170 NFBD1 PPGRPAEVHLERAQPFGFIDsDtDAEEERIPAtPVVIPMKK
Q14676 S376 SIGNOR|PSP MDC1 KIAA0170 NFBD1 VGTRGPGAPGLAHLQEsQAGsDtDVEEGKAPQAVPLEKSQA
Q14676 S402 PSP MDC1 KIAA0170 NFBD1 EGKAPQAVPLEKSQAsMVINsDtDDEEEVsAALTLAHLKEs
Q14676 S453 PSP MDC1 KIAA0170 NFBD1 EDMPQRVVLLQRsQtttERDsDtDVEEEELPVENREAVLKD
Q14676 T220 PSP MDC1 KIAA0170 NFBD1 GHSPVLGGLGPPFAFNLNsDtDVEEGQQPATEEASSAARRG
Q14676 T301 SIGNOR|PSP MDC1 KIAA0170 NFBD1 GVVPAGVILERsQPPGEDsDtDVDDDsRPPGRPAEVHLERA
Q14676 T331 PSP MDC1 KIAA0170 NFBD1 GRPAEVHLERAQPFGFIDsDtDAEEERIPAtPVVIPMKKRK
Q14676 T378 SIGNOR|PSP MDC1 KIAA0170 NFBD1 TRGPGAPGLAHLQEsQAGsDtDVEEGKAPQAVPLEKSQAsM
Q14676 T404 PSP MDC1 KIAA0170 NFBD1 KAPQAVPLEKSQAsMVINsDtDDEEEVsAALTLAHLKEsQP
Q14676 T455 SIGNOR|PSP MDC1 KIAA0170 NFBD1 MPQRVVLLQRsQtttERDsDtDVEEEELPVENREAVLKDHT
Q14694 S576 Sugiyama USP10 KIAA0190 sNGPKNHSVNEEEQEEQGEGsEDEWEQVGPRNKTSVTRQAD
Q14761 S153 SIGNOR|PSP PTPRCAP LPAP QCGEASSPEQVPVRAEEARDsDtEGDLVLGsPGPAsAGGsA
Q14839 S308 PSP CHD4 PKKVAPLKIKLGGFGSKRKRsssEDDDLDVEsDFDDAsINS
Q14839 S310 PSP CHD4 KVAPLKIKLGGFGSKRKRsssEDDDLDVEsDFDDAsINSYS
Q14839 S428 PSP CHD4 KWSCPHCEKEGIQWEAKEDNsEGEEILEEVGGDLEEEDDHH
Q14940 S702 SIGNOR|PSP SLC9A5 NHE5 NGKHRGLGFQDTAAVILTVEsEEEEEEsDssEtEKEDDEGI
Q14940 S709 SIGNOR|PSP SLC9A5 NHE5 GFQDTAAVILTVEsEEEEEEsDssEtEKEDDEGIIFVARAT
Q14940 S711 SIGNOR|PSP SLC9A5 NHE5 QDTAAVILTVEsEEEEEEsDssEtEKEDDEGIIFVARATSE
Q14940 S712 SIGNOR|PSP SLC9A5 NHE5 DTAAVILTVEsEEEEEEsDssEtEKEDDEGIIFVARATSEV
Q14940 T714 SIGNOR|PSP SLC9A5 NHE5 AAVILTVEsEEEEEEsDssEtEKEDDEGIIFVARATSEVLQ
Q15003 S570 PSP NCAPH BRRN BRRN1 CAPH KIAA0074 YDYNNPNDTSNFCPGLQAADsDDEDLDDLFVGPVGNSDLsP
Q15019 S218 SIGNOR|PSP|Sugiyama SEPTIN2 DIFF6 KIAA0158 NEDD5 SEPT2 RILDEIEEHNIKIyHLPDAEsDEDEDFKEQtRLLKASIPFS
Q15084 S22 PSP PDIA6 ERP5 P5 TXNDC7 ALLVLGLVSCTFFLAVNGLYsSSDDVIELTPSNFNREVIQS
Q15084 S428 PSP|Sugiyama PDIA6 ERP5 P5 TXNDC7 EREPWDGRDGELPVEDDIDLsDVELDDLGKDEL________
Q15185 S113 GPS6|SIGNOR|ELM|PSP|Sugiyama PTGES3 P23 TEBP RAKLNWLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGD
Q15185 S118 GPS6|SIGNOR|ELM|PSP PTGES3 P23 TEBP WLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGDEDVDL
Q15287 S53 GPS6|ELM|PSP RNPS1 LDC2 DRSDEKSKDRSKDKGATKESsEKDRGRDKTRKRRSASSGSS
Q15555 S236 PSP MAPRE2 RP1 stPsRPssAKRAsssGsAsKsDKDLEtQVIQLNEQVHsLKL
Q15596 S469 PSP NCOA2 BHLHE75 SRC2 TIF2 HVSGMQATtPQGSNYALKMNsPsQSSPGMNPGQPTSMLsPR
Q15596 S487 PSP NCOA2 BHLHE75 SRC2 TIF2 MNsPsQSSPGMNPGQPTSMLsPRHRMsPGVAGsPRIPPSQF
Q15596 S493 PSP NCOA2 BHLHE75 SRC2 TIF2 SSPGMNPGQPTSMLsPRHRMsPGVAGsPRIPPSQFSPAGSL
Q15596 S499 PSP NCOA2 BHLHE75 SRC2 TIF2 PGQPTSMLsPRHRMsPGVAGsPRIPPSQFSPAGSLHSPVGV
Q15653 S313 PSP NFKBIB IKBB TRIP9 LRAHGAPEPEGEDEKSGPCSsSsDSDSGDEGDEYDDIVVHS
Q15653 S315 PSP NFKBIB IKBB TRIP9 AHGAPEPEGEDEKSGPCSsSsDSDSGDEGDEYDDIVVHSSR
Q15672 S18 SIGNOR|PSP TWIST1 BHLHA38 TWIST ___MMQDVSSSPVSPADDSLsNsEEEPDRQQPPSGKRGGRK
Q15672 S20 SIGNOR|PSP TWIST1 BHLHA38 TWIST _MMQDVSSSPVSPADDSLsNsEEEPDRQQPPSGKRGGRKRR
Q15906 S41 ELM VPS72 TCFL1 YL1 LEAEEEDEFYQTTYGGFTEEsGDDEYQGDQsDTEDEVDsDF
Q15906 S51 ELM VPS72 TCFL1 YL1 QTTYGGFTEEsGDDEYQGDQsDTEDEVDsDFDIDEGDEPSs
Q15906 S59 ELM VPS72 TCFL1 YL1 EEsGDDEYQGDQsDTEDEVDsDFDIDEGDEPSsDGEAEEPR
Q15906 S71 ELM VPS72 TCFL1 YL1 sDTEDEVDsDFDIDEGDEPSsDGEAEEPRRKRRVVtKAYKE
Q16181 T228 Sugiyama SEPTIN7 CDC10 SEPT7 KKQIMKEIQEHKIKIyEFPEtDDEEENKLVKKIKDRLPLAV
Q16543 S13 GPS6|SIGNOR|ELM|iPTMNet|PSP CDC37 CDC37A ________MVDysVWDHIEVsDDEDEtHPNIDTASLFRWRH
Q16623 S14 SIGNOR|ELM|iPTMNet|PSP STX1A STX1 _______MKDRTQELRtAKDsDDDDDVAVTVDRDRFMDEFF
Q16625 S408 ELM|PSP OCLN GRSKRTEQDHyEtDyttGGEsCDELEEDWIREYPPItSDQQ
Q16625 T400 PSP OCLN RAPAKGRAGRSKRTEQDHyEtDyttGGEsCDELEEDWIREY
Q16625 T404 ELM|PSP OCLN KGRAGRSKRTEQDHyEtDyttGGEsCDELEEDWIREYPPIt
Q16665 T796 SIGNOR|iPTMNet HIF1A BHLHE78 MOP1 PASD8 SDLACRLLGQSMDESGLPQLtSYDCEVNAPIQGsRNLLQGE
Q16666 S132 GPS6|SIGNOR|ELM|iPTMNet|PSP IFI16 IFNGIP1 sstVKtEGAEAtPGAQKRKKsTKEKAGPKGsKVsEEQtQPP
Q32P28 S479 Sugiyama P3H1 GROS1 LEPRE1 PSEC0109 LTMNSKLLNGSQRVVMDGVIsDHECQELQRLTNVAATSGDG
Q5VZL5 S122 Sugiyama ZMYM4 KIAA0425 ZNF262 VssIHtDDsLEVERRVtQHEsDNENEIQIQNKLKKDFPKQF
Q5VZL5 T118 Sugiyama ZMYM4 KIAA0425 ZNF262 KDNLVssIHtDDsLEVERRVtQHEsDNENEIQIQNKLKKDF
Q6NXS1 S121 PSP PPP1R2B PPP1R2P3 AKKLAAAEGLEPKyRIQEQEssGEEDsDLsPEEREKKRQFE
Q6NXS1 S122 PSP PPP1R2B PPP1R2P3 KKLAAAEGLEPKyRIQEQEssGEEDsDLsPEEREKKRQFEM
Q6NXS1 S127 PSP PPP1R2B PPP1R2P3 AEGLEPKyRIQEQEssGEEDsDLsPEEREKKRQFEMRRKLH
Q6PKG0 S627 Sugiyama LARP1 KIAA0731 LARP FLFDEEMEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVt
Q6PKG0 S631 Sugiyama LARP1 KIAA0731 LARP EEMEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVtQtPH
Q6VY07 S278 SIGNOR|ELM|PSP PACS1 KIAA1175 IDHEGIKSKLSDRSPDIDNYsEEEEESFSSEQEGSDDPLHG
Q6ZMG9 S341 SIGNOR|PSP CERS6 LASS6 LIVKIACKAVSRGKVSKDDRsDIEsssDEEDSEPPGKNPHT
Q6ZMG9 S345 SIGNOR|PSP CERS6 LASS6 IACKAVSRGKVSKDDRsDIEsssDEEDSEPPGKNPHTATTT
Q6ZMG9 S346 SIGNOR|PSP CERS6 LASS6 ACKAVSRGKVSKDDRsDIEsssDEEDSEPPGKNPHTATTTN
Q6ZMG9 S347 SIGNOR|PSP CERS6 LASS6 CKAVSRGKVSKDDRsDIEsssDEEDSEPPGKNPHTATTTNG
Q712K3 S233 GPS6|SIGNOR|ELM|iPTMNet|PSP UBE2R2 CDC34B UBC3B DDIDDEDEEEEDADCYDDDDsGNEES_______________
Q7Z4V5 S369 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 EKERRRERADRGEAERGsGGssGDELREDDEPVKKRGRKGR
Q7Z4V5 S370 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 KERRRERADRGEAERGsGGssGDELREDDEPVKKRGRKGRG
Q86WR0 S204 Sugiyama CCDC25 RSYssLMKVENMSSNQDGNDsDEFM________________
Q8IVP5 S13 SIGNOR|PSP FUNDC1 ________MATRNPPPQDyEsDDDsyEVLDLTEYARRHQWW
Q8N163 T454 SIGNOR CCAR2 DBC1 KIAA1967 PTLEEWEALCQQKAAEAAPPtQEAQGEtEPTEQAPDALEQA
Q8N5B7 S350 SIGNOR|PSP CERS5 LASS5 LIARIALKALIRGKVSKDDRsDVEsssEEEDVTTCTKSPCD
Q8N5B7 S354 SIGNOR|PSP CERS5 LASS5 IALKALIRGKVSKDDRsDVEsssEEEDVTTCTKSPCDSSSS
Q8N5B7 S355 SIGNOR|PSP CERS5 LASS5 ALKALIRGKVSKDDRsDVEsssEEEDVTTCTKSPCDSSSSN
Q8N5B7 S356 SIGNOR|PSP CERS5 LASS5 LKALIRGKVSKDDRsDVEsssEEEDVTTCTKSPCDSSSSNG
Q8N5P1 T32 PSP ZC3H8 ZC3HDC8 NPALGKtAtDsDERIDDEIDtEVEETQEEKIKLECEQIPKK
Q8N6T7 S338 PSP SIRT6 SIR2L6 EPCAQHNGsEPAsPKRERPtsPAPHRPPKRVKAKAVPS___
Q8NE71 S109 SIGNOR|PSP|Sugiyama ABCF1 ABC50 DDDGEEKELMERLKKLsVPtsDEEDEVPAPKPRGGKKTKGG
Q8NE71 S140 SIGNOR|PSP ABCF1 ABC50 PRGGKKTKGGNVFAALIQDQsEEEEEEEKHPPKPAKPEKNR
Q8NE71 T108 Sugiyama ABCF1 ABC50 VDDDGEEKELMERLKKLsVPtsDEEDEVPAPKPRGGKKTKG
Q8NEL9 S104 SIGNOR|PSP DDHD1 KIAA1705 LsDENYDFsSAESGSSLRYYsEGESGGGGSSLSLHPPQQPP
Q8NEL9 S711 SIGNOR DDHD1 KIAA1705 NPLPYEHMKPSFLNPAKEPtsVSENEGIstIPsPVtsPVLs
Q8NEL9 S92 SIGNOR DDHD1 KIAA1705 DDHNHHLALDPCLsDENYDFsSAESGSSLRYYsEGESGGGG
Q8NEY1 S296 Sugiyama NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1 MSSLRGSQVTHSSLEMTCYDsDDANPRsVssLsNRssPLSW
Q8NHW5 S304 Sugiyama RPLP0P6 DTTAAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD_______
Q8NHW5 S307 Sugiyama RPLP0P6 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
Q8TAE8 S221 PSP GADD45GIP1 MRPL59 PLINP1 PRG6 ARAAALAAAVAQDPAASGAPss___________________
Q8TEA8 S179 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 QLSKLEKQQQRKEKTRAKGPsEssKERNtPRKEDRsAssGA
Q8TEA8 S181 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 SKLEKQQQRKEKTRAKGPsEssKERNtPRKEDRsAssGAEG
Q8TEA8 S182 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 KLEKQQQRKEKTRAKGPsEssKERNtPRKEDRsAssGAEGD
Q8TEA8 S194 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 RAKGPsEssKERNtPRKEDRsAssGAEGDVssEREP_____
Q8TEA8 S196 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 KGPsEssKERNtPRKEDRsAssGAEGDVssEREP_______
Q8TEA8 S197 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 GPsEssKERNtPRKEDRsAssGAEGDVssEREP________
Q8TEA8 S204 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 ERNtPRKEDRsAssGAEGDVssEREP_______________
Q8TEA8 S205 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 RNtPRKEDRsAssGAEGDVssEREP________________
Q8TEA8 T187 SIGNOR|PSP DTD1 C20orf88 DUEB HARS2 QQRKEKTRAKGPsEssKERNtPRKEDRsAssGAEGDVssER
Q8TF40 S938 PSP FNIP1 KIAA1961 KESSDKKIAVGTEWDIPRNEssDsALGDsEsEDTGHDMTRQ
Q8TF40 S939 PSP FNIP1 KIAA1961 ESSDKKIAVGTEWDIPRNEssDsALGDsEsEDTGHDMTRQV
Q8TF40 S941 PSP FNIP1 KIAA1961 SDKKIAVGTEWDIPRNEssDsALGDsEsEDTGHDMTRQVSS
Q8TF40 S946 PSP FNIP1 KIAA1961 AVGTEWDIPRNEssDsALGDsEsEDTGHDMTRQVSSYYGGE
Q8TF40 S948 PSP FNIP1 KIAA1961 GTEWDIPRNEssDsALGDsEsEDTGHDMTRQVSSYYGGEQE
Q8WVC0 S66 Sugiyama LEO1 RDL DQDERGDSGQPSNKELFGDDsEDEGAsHHsGSDNHSERSDN
Q8WXI9 S129 Sugiyama GATAD2B KIAA1150 ARRsEPERGRLtPsPDIIVLsDNEAssPRsSsRMEERLKAA
Q92538 S292 SIGNOR|PSP GBF1 KIAA0248 TPISSASSEAASAVVSPSTDsGLEFssQttsKEDLtDLEQP
Q92538 S297 SIGNOR|PSP GBF1 KIAA0248 ASSEAASAVVSPSTDsGLEFssQttsKEDLtDLEQPGsPGy
Q92598 S509 SIGNOR|iPTMNet HSPH1 HSP105 HSP110 KIAA0201 IFTISTASMVEKVPtEENEMssEADMECLNQRPPENPDTDK
Q92626 S1300 Sugiyama PXDN KIAA0230 MG50 PRG2 PXD01 VPO VPO1 NITRVQSDVFRVAEFPHGyGsCDEIPRVDLRVWQDCCEDCR
Q92688 T244 SIGNOR|PSP ANP32B APRIL PHAPI2 DEDEDEEEEEGGKGEKRKREtDDEGEDD_____________
Q92769 S394 GPS6|SIGNOR|ELM|PSP HDAC2 LPHAPGVQMQAIPEDAVHEDsGDEDGEDPDKRIsIRAsDKR
Q92769 S422 SIGNOR|ELM HDAC2 PDKRIsIRAsDKRIACDEEFsDsEDEGEGGRRNVADHKKGA
Q92769 S424 SIGNOR|ELM HDAC2 KRIsIRAsDKRIACDEEFsDsEDEGEGGRRNVADHKKGAKK
Q92882 S213 Sugiyama OSTF1 QGTDAVRtLsNAEDyLDDEDsD___________________
Q92915 S228 SIGNOR|PSP FGF14 FHF4 EPSLHDVGETVPKPGVTPsKsTsASAIMNGGKPVNKSKTT_
Q92915 S230 SIGNOR|PSP FGF14 FHF4 SLHDVGETVPKPGVTPsKsTsASAIMNGGKPVNKSKTT___
Q92973 S339 Sugiyama TNPO1 KPNB2 MIP1 TRN SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE
Q93009 S18 SIGNOR|PSP USP7 HAUSP ___MNHQQQQQQQKAGEQQLsEPEDMEMEAGDTDDPPRITQ
Q96D46 S468 Sugiyama NMD3 CGI-07 EDEAIRKNVNIyRDsAIPVEsDtDDEGAPRISLAEMLEDLH
Q96D46 T470 Sugiyama NMD3 CGI-07 EAIRKNVNIyRDsAIPVEsDtDDEGAPRISLAEMLEDLHIs
Q96EB6 S659 SIGNOR|PSP SIRT1 SIR2L1 GNQYLFLPPNRYIFHGAEVYsDsEDDVLSSsSCGSNSDSGT
Q96EB6 S661 SIGNOR|PSP SIRT1 SIR2L1 QYLFLPPNRYIFHGAEVYsDsEDDVLSSsSCGSNSDSGTCQ
Q96FW1 S16 SIGNOR|PSP OTUB1 OTB1 OTU1 HSPC263 _____MAAEEPQQQKQEPLGsDsEGVNCLAyDEAIMAQQDR
Q96G74 S177 SIGNOR|PSP OTUD5 GVGAVGGGsPEREEVGAGyNsEDEyEAAAARIEAMDPATVE
Q96HZ4 S183 SIGNOR|iPTMNet|PSP HES6 BHLHB41 AGGAPGSPIPSPPGPGDDLCsDLEEAPEAELSQAPAEGPDL
Q96IZ0 S231 PSP PAWR PAR4 SsyLLQEPPRTVSGRyKsttsVsEEDVsSRYsRTDRSGFPR
Q96KQ7 S211 PSP EHMT2 BAT8 C6orf30 G9A KMT1C NG36 GNGQPPVPEKRPPEIQHFRMsDDVHsLGKVTSDLAKRRKLN
Q96NY9 S87 SIGNOR|PSP MUS81 QHFGDGLCRMLDERLQRHRtsGGDHAPDsPsGENsPAPQGR
Q96PX8 S695 SIGNOR|PSP SLITRK1 KIAA1910 LRRC12 UNQ233/PRO266 NGPYNADGAHRVYDCGSHSLsD___________________
Q96QK1 S759 Sugiyama VPS35 MEM3 TCCCTA00141 TIQVLNQLIQKIREDLPNLEssEEtEQINKHFHNtLEHLRL
Q96RL1 S44 PSP UIMC1 RAP80 RXRIP110 TTssVsVKRKRRLEDAFIVIsDsDGEEPKEENGLQKTKTKQ
Q96RL1 S46 PSP UIMC1 RAP80 RXRIP110 ssVsVKRKRRLEDAFIVIsDsDGEEPKEENGLQKTKTKQSN
Q96SB4 S222 ELM SRPK1 YLHTKCRIIHTDIKPENILLsVNEQYIRRLAAEATEWQRSG
Q96SB4 S51 GPS6|PSP SRPK1 RGsAPHSESDLPEQEEEILGsDDDEQEDPNDYCKGGYHLVK
Q96SB4 S555 GPS6|PSP SRPK1 WSTACMAFELATGDYLFEPHsGEEYTRDEDHIALIIELLGK
Q99250 S1112 SIGNOR SCN2A HBA NAC2 SCN2A1 SCN2A2 YMSFINNPSLTVTVPIAVGEsDFENLNTEEFSsEsDMEESK
Q99250 S1124 SIGNOR SCN2A HBA NAC2 SCN2A1 SCN2A2 TVPIAVGEsDFENLNTEEFSsEsDMEESKEKLNATSSSEGS
Q99250 S1126 SIGNOR SCN2A HBA NAC2 SCN2A1 SCN2A2 PIAVGEsDFENLNTEEFSsEsDMEESKEKLNATSSSEGSTV
Q99613 S39 Sugiyama EIF3C EIF3S8 GEELVTKPVGGNyGKQPLLLsEDEEDTKRVVRSAKDKRFEE
Q99638 S341 PSP RAD9A VLPsIsLsPGPQPPKsPGPHsEEEDEAEPStVPGtPPPKKF
Q99638 S387 PSP RAD9A GsILAPVRsPQGPsPVLAEDsEGEG________________
Q99733 S121 Sugiyama NAP1L4 NAP2 PLFDKRREFItGDVEPtDAEsEWHsENEEEEKLAGDMKSKV
Q99733 S125 Sugiyama NAP1L4 NAP2 KRREFItGDVEPtDAEsEWHsENEEEEKLAGDMKSKVVVTE
Q99808 S254 SIGNOR|PSP SLC29A1 ENT1 YYQQLKLEGPGEQEtKLDLIsKGEEPRAGKEEsGVsVsNsQ
Q9BPX3 S674 Sugiyama NCAPG CAPG NYMEL3 IEPFKTKKIKTLHCEGtEINsDDEQEsKEVEETATAKNVLK
Q9BPX3 S973 PSP NCAPG CAPG NYMEL3 QRKVTVsARTNRRCQTAEADsEsDHEVPEPESEMKMRLPRR
Q9BPX3 S975 PSP NCAPG CAPG NYMEL3 KVTVsARTNRRCQTAEADsEsDHEVPEPESEMKMRLPRRAK
Q9BQE3 S439 Sugiyama TUBA1C TUBA6 SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BRS2 T410 SIGNOR|PSP RIOK1 RIO1 ITHENMDAYLSKAMEIASQRtKEERssQDHVDEEVFKRAYI
Q9BSI4 S396 PSP TINF2 TIN2 PVCPPSLCSSVITIGDLVLDsDEEENGQGEGKESLENYQKT
Q9BW27 S617 Sugiyama NUP85 NUP75 PCNT1 TYELMRCLEDLTSRRPVHGEsDtEQLQDDDIETTKVEMLRL
Q9BW27 T619 Sugiyama NUP85 NUP75 PCNT1 ELMRCLEDLTSRRPVHGEsDtEQLQDDDIETTKVEMLRLSL
Q9BXJ9 S855 Sugiyama NAA15 GA19 NARG1 NATH TBDN100 ALAFMPPGYEEDMKItVNGDssAEAEELANEI_________
Q9BXW9 S882 SIGNOR|PSP FANCD2 FACD IRKKGKIERKQKTDGSKTSssDtLsEEKNsECDPtPsHRGQ
Q9BXW9 S886 SIGNOR|PSP FANCD2 FACD GKIERKQKTDGSKTSssDtLsEEKNsECDPtPsHRGQLNKE
Q9BXW9 S891 SIGNOR|PSP FANCD2 FACD KQKTDGSKTSssDtLsEEKNsECDPtPsHRGQLNKEFTGKE
Q9BXW9 S898 SIGNOR|PSP FANCD2 FACD KTSssDtLsEEKNsECDPtPsHRGQLNKEFTGKEEKTSLLL
Q9BXW9 T884 SIGNOR|PSP FANCD2 FACD KKGKIERKQKTDGSKTSssDtLsEEKNsECDPtPsHRGQLN
Q9BXW9 T896 SIGNOR|PSP FANCD2 FACD GSKTSssDtLsEEKNsECDPtPsHRGQLNKEFTGKEEKTSL
Q9BYF1 S787 PSP ACE2 UNQ868/PRO1885 DRKKKNKARsGENPyAsIDIsKGENNPGFQNTDDVQTSF__
Q9C0B1 T150 PSP FTO KIAA1752 AEIAAACETFLKLNDYLQIEtIQALEELAAKEKANEDAVPL
Q9H1E3 S113 Sugiyama NUCKS1 NUCKS JC7 RQAASKAASKQREMLMEDVGsEEEQEEEDEAPFQEKDsGsD
Q9H1E3 S132 Sugiyama NUCKS1 NUCKS JC7 GsEEEQEEEDEAPFQEKDsGsDEDFLMEDDDDsDyGSsKKK
Q9H257 T531 SIGNOR|PSP CARD9 MQKGWRQGEEDRENTTGSDNtDtEGS_______________
Q9H257 T533 SIGNOR|PSP CARD9 KGWRQGEEDRENTTGSDNtDtEGS_________________
Q9H2G2 S347 SIGNOR SLK KIAA0204 STK2 tENsLPIPAsKRAssDLsIAssEEDKLsQNACILEsVSEKt
Q9H2G2 S348 SIGNOR SLK KIAA0204 STK2 ENsLPIPAsKRAssDLsIAssEEDKLsQNACILEsVSEKtE
Q9H3N1 S247 Sugiyama TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 EsAQPLKKVEEEQEADEEDVsEEEAEsKEGtNKDFPQNAIR
Q9H6T3 S116 PSP RPAP3 LDVDRILDELDKDDstHEsLsQEsEsEEDGIHVDSQKALVL
Q9H6T3 S119 PSP RPAP3 DRILDELDKDDstHEsLsQEsEsEEDGIHVDSQKALVLKEK
Q9H6T3 S121 PSP RPAP3 ILDELDKDDstHEsLsQEsEsEEDGIHVDSQKALVLKEKGN
Q9H6Y2 S14 Sugiyama WDR55 _______MDRTCEERPAEDGsDEEDPDsMEAPTRIRDtPED
Q9HA82 S342 SIGNOR|PSP CERS4 LASS4 LILRMLYSFMKKGQMEKDIRsDVEEsDssEEAAAAQEPLQL
Q9HA82 S347 SIGNOR|PSP CERS4 LASS4 LYSFMKKGQMEKDIRsDVEEsDssEEAAAAQEPLQLKNGAA
Q9HA82 S349 SIGNOR|PSP CERS4 LASS4 SFMKKGQMEKDIRsDVEEsDssEEAAAAQEPLQLKNGAAGG
Q9HA82 S350 SIGNOR|PSP CERS4 LASS4 FMKKGQMEKDIRsDVEEsDssEEAAAAQEPLQLKNGAAGGP
Q9HCF6 S1195 GPS6 TRPM3 KIAA1616 LTRPC3 IFSHMTMIFQHLCCRWRKHEsDPDERDYGLKLFITDDELKK
Q9HCN4 S338 Sugiyama GPN1 MBDIN RPAP4 XAB1 HUSSY-23 HPsDLILtRGTLDEEDEEADsDtDDIDHRVTEESHEEPAFQ
Q9HCU9 S30 SIGNOR|PSP BRMS1 TEEMEAEGDsAAEMNGEEEEsEEERSGSQTESEEESSEMDD
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQB0 S58 SIGNOR|ELM TCF7L2 TCF4 ERDLADVKSSLVNESEtNQNsssDSEAERRPPPRSESFRDK
Q9NQB0 S59 SIGNOR|ELM TCF7L2 TCF4 RDLADVKSSLVNESEtNQNsssDSEAERRPPPRSESFRDKS
Q9NQB0 S60 SIGNOR|ELM TCF7L2 TCF4 DLADVKSSLVNESEtNQNsssDSEAERRPPPRSESFRDKSR
Q9NR28 S230 Sugiyama DIABLO SMAC EAQIEELRQKTQEEGEERAEsEQEAyLRED___________
Q9NTJ3 S28 Sugiyama SMC4 CAPC SMC4L1 PSTARRREEGPPPPsPDGAssDAEPEPPsGRtEsPAtAAEt
Q9NY61 S155 PSP AATF CHE1 DED HSPC277 ESKKSRsHsAKtPGFSVQsIsDFEKFTKGMDDLGSSEEEED
Q9NY61 S288 PSP AATF CHE1 DED HSPC277 GPEFSsALKNSHKALKALLRsLVGLQEELLFQYPDTRYLVD
Q9NY61 S320 PSP AATF CHE1 DED HSPC277 YPDTRYLVDGtKPNAGsEEIssEDDELVEEKKQQRRRVPAK
Q9NY61 S321 PSP AATF CHE1 DED HSPC277 PDTRYLVDGtKPNAGsEEIssEDDELVEEKKQQRRRVPAKR
Q9NYV6 S170 SIGNOR|PSP RRN3 TIFIA MIASHFVPPRVIIKEGDVDVsDsDDEDDNLPANFDTCHRAL
Q9NYV6 S172 SIGNOR|PSP RRN3 TIFIA ASHFVPPRVIIKEGDVDVsDsDDEDDNLPANFDTCHRALQI
Q9NZQ7 T285 PSP CD274 B7H1 PDCD1L1 PDCD1LG1 PDL1 RMMDVKKCGIQDtNsKKQsDtHLEEt_______________
Q9NZQ7 T290 PSP CD274 B7H1 PDCD1L1 PDCD1LG1 PDL1 KKCGIQDtNsKKQsDtHLEEt____________________
Q9UBE0 S12 Sugiyama SAE1 AOS1 SUA1 UBLE1A _________MVEKEEAGGGIsEEEAAQyDRQIRLWGLEAQK
Q9UBF6 T10 GPS6|SIGNOR|ELM|PSP RNF7 RBX2 ROC2 SAG ___________MADVEDGEEtCALAsHsGssGsKSGGDKMF
Q9UBN7 S458 PSP HDAC6 KIAA0901 JM21 LVRSTETVERDNMEEDNVEEsEEEGPWEPPVLPILTWPVLQ
Q9UBS4 S78 Sugiyama DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080 PDDPQAQEKFQDLGAAyEVLsDSEKRKQyDTyGEEGLKDGH
Q9UD71 S102 SIGNOR PPP1R1B DARPP32 VQRIAESHLQSIsNLNENQAsEEEDELGELRELGYPREEDE
Q9UD71 S45 SIGNOR PPP1R1B DARPP32 VEMIRRRRPtPAMLFRLsEHssPEEEAsPHQRASGEGHHLK
Q9UD71 S66 iPTMNet PPP1R1B DARPP32 sPEEEAsPHQRASGEGHHLKsKRPNPCAYtPPSLKAVQRIA
Q9UER7 S737 SIGNOR|PSP DAXX BING2 DAP6 PGTCKTSVATQCDPEEIIVLsDsD_________________
Q9UER7 S739 SIGNOR|PSP DAXX BING2 DAP6 TCKTSVATQCDPEEIIVLsDsD___________________
Q9UGP8 S574 SIGNOR|PSP SEC63 DNAJC23 SEC63L GVVGNEAAVKEDEEEVsDKGsDsEEEETNRDsQSEKDDGsD
Q9UGP8 S576 SIGNOR|PSP SEC63 DNAJC23 SEC63L VGNEAAVKEDEEEVsDKGsDsEEEETNRDsQSEKDDGsDRD
Q9UGP8 S748 SIGNOR|PSP SEC63 DNAJC23 SEC63L QWDTAIEGDEDQEDSEGFEDsFEEEEEEEEDDD________
Q9UHC3 S5 iPTMNet ASIC3 ACCN3 SLNAC1 TNAC1 ________________MKPTsGPEEARRPASDIRVFASNCS
Q9UHH9 S347 SIGNOR|PSP IP6K2 IHPK2 TCCCIA00113 YSSSLLVIYDGKERPEVVLDsDAEDLEDLsEEsADESAGAY
Q9UHH9 S356 SIGNOR|PSP IP6K2 IHPK2 TCCCIA00113 DGKERPEVVLDsDAEDLEDLsEEsADESAGAYAYKPIGASS
Q9UJU2 S42 PSP LEF1 EMIPFKDEGDPQKEKIFAEIsHPEEEGDLADIKSSLVNEsE
Q9UJU2 S61 PSP LEF1 IsHPEEEGDLADIKSSLVNEsEIIPASNGHEVARQAQTSQE
Q9UJY5 S355 SIGNOR|PSP GGA1 PAMPTRPGEQASPEQPSASVsLLDDELMSLGLSDPTPPSGP
Q9UKD2 S229 PSP MRTO4 C1orf33 MRT4 DSQSGRFQQMGDDLPESASEsTEEsDsEDDD__________
Q9UKD2 S233 PSP MRTO4 C1orf33 MRT4 GRFQQMGDDLPESASEsTEEsDsEDDD______________
Q9UKD2 S235 PSP MRTO4 C1orf33 MRT4 FQQMGDDLPESASEsTEEsDsEDDD________________
Q9UKS6 S276 Sugiyama PACSIN3 SSSEKFHELHRDLHQGIEAAsDEEDLRWWRSTHGPGMAMNW
Q9UKX2 S1921 PSP MYH2 MYHSA2 KFRKLQHELEEAEERADIAEsQVNKLRVKSREVHTKVISEE
Q9ULV4 S463 SIGNOR|PSP CORO1C CRN2 CRNN4 EILKEIKSIKDTICNQDERIsKLEQQMAKIAA_________
Q9UMD9 S542 GPS6|PSP COL17A1 BP180 BPAG2 DRLQGMAPAAGADLDKIGLHsDsQEELWMFVRKKLMMEQEN
Q9UMD9 S544 GPS6|PSP COL17A1 BP180 BPAG2 LQGMAPAAGADLDKIGLHsDsQEELWMFVRKKLMMEQENGN
Q9UNN4 S356 SIGNOR|ELM|iPTMNet GTF2A1L ALF GTF2A1LF IRVTDDDIGEIIQVDGSGDTssNEEIGSTRDADENEFLGNI
Q9UNN4 S357 SIGNOR|ELM|iPTMNet GTF2A1L ALF GTF2A1LF RVTDDDIGEIIQVDGSGDTssNEEIGSTRDADENEFLGNID
Q9UNN4 S418 SIGNOR|ELM|iPTMNet GTF2A1L ALF GTF2A1LF TNSSDNEDPQVNIVEEDPLNsGDDVsEQDVPDLFDTDNVIV
Q9UNN4 S423 SIGNOR|ELM|iPTMNet GTF2A1L ALF GTF2A1LF NEDPQVNIVEEDPLNsGDDVsEQDVPDLFDTDNVIVCQYDK
Q9UNN5 S289 GPS6|SIGNOR|ELM|iPTMNet|PSP FAF1 UBXD12 UBXN3A CGI-03 ssPAQTREQSEEQITDVHMVsDsDGDDFEDATEFGVDDGEV
Q9UNN5 S291 GPS6|SIGNOR|ELM|iPTMNet|PSP FAF1 UBXD12 UBXN3A CGI-03 PAQTREQSEEQITDVHMVsDsDGDDFEDATEFGVDDGEVFG
Q9UPP1 S854 SIGNOR|PSP PHF8 KIAA1111 ZNF422 sLDEQDSLGACFKDAEYIyPsLEsDDDDPALKSRPKKKKNS
Q9UQ88 S271 Sugiyama CDK11A CDC2L2 CDC2L3 PITSLREB AQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSAESGSGS
Q9UQE7 S1067 SIGNOR|PSP SMC3 BAM BMH CSPG6 SMC3L1 LVPGGKATLVMKKGDVEGsQsQDEGEGsGEsERGsGsQssV
Q9Y237 S19 SIGNOR|ELM|PSP PIN4 __MPPKGKSGSGKAGKGGAAsGSDSADKKAQGPKGGGNAVK
Q9Y365 S284 SIGNOR|PSP STARD10 SDCCAG28 CGI-52 DESAVAESREERMGGAGGEGsDDDtsLt_____________
Q9Y3F4 S254 Sugiyama STRAP MAWD UNRIP EKEFLVAGGEDFKLyKyDyNsGEELEsyKGHFGPIHCVRFS
Q9Y4R8 S485 PSP TELO2 KIAA0683 PAETPAEIVDGGVPQAQLAGsDsDLDsDDEFVPYDMSGDRE
Q9Y4R8 S487 SIGNOR|PSP TELO2 KIAA0683 ETPAEIVDGGVPQAQLAGsDsDLDsDDEFVPYDMSGDRELK
Q9Y4R8 S491 SIGNOR|PSP TELO2 KIAA0683 EIVDGGVPQAQLAGsDsDLDsDDEFVPYDMSGDRELKSSKA
Q9Y5B0 S575 SIGNOR|ELM|iPTMNet|PSP CTDP1 FCP1 ETESQNSELSGVTAGESLDQsMEEEEEEDtDEDDHLIYLEE
Q9Y5B0 S740 SIGNOR|ELM|iPTMNet|PSP CTDP1 FCP1 KVEEQLFPLRDDHTKAQRENsPAAFPDREGVPPTALFHPMP
Q9Y5B0 S942 PSP CTDP1 FCP1 LNEEDAASESSRESSNEDEGsSsEADEMAKALEAELNDLM_
Q9Y5B0 S944 PSP CTDP1 FCP1 EEDAASESSRESSNEDEGsSsEADEMAKALEAELNDLM___
Q9Y5B0 T584 PSP CTDP1 FCP1 SGVTAGESLDQsMEEEEEEDtDEDDHLIYLEEILVRVHTDY
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y618 S2511 PSP NCOR2 CTG26 PHHAWDEEPKPLLCSQYETLsDSE_________________
Q9Y624 S34 iPTMNet F11R JAM1 JCAM UNQ264/PRO301 LFILAILLCSLALGSVTVHSsEPEVRIPENNPVKLSCAYSG
Q9Y696 S236 Sugiyama CLIC4 GIWRYLtNAysRDEFtNtCPsDKEVEIAysDVAKRLTK___
Q9Y6K1 S390 SIGNOR|PSP DNMT3A YEVLQVASSRAGKLFPVCHDsDEsDTAKAVEVQNKPMIEWA
Q9Y6K1 S393 SIGNOR|PSP DNMT3A LQVASSRAGKLFPVCHDsDEsDTAKAVEVQNKPMIEWALGG
Q9Y6W5 S482 SIGNOR|PSP WASF2 WAVE2 RDVVGNDVAtILsRRIAVEYsDsEDDssEFDEDDWsD____
Q9Y6W5 S484 SIGNOR|PSP WASF2 WAVE2 VVGNDVAtILsRRIAVEYsDsEDDssEFDEDDWsD______
Q9Y6W5 S488 SIGNOR|PSP WASF2 WAVE2 DVAtILsRRIAVEYsDsEDDssEFDEDDWsD__________
Q9Y6W5 S489 PSP WASF2 WAVE2 VAtILsRRIAVEYsDsEDDssEFDEDDWsD___________
Q9Y6W5 S497 SIGNOR|PSP WASF2 WAVE2 IAVEYsDsEDDssEFDEDDWsD___________________
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.148460e-09 8.940 0 0
Metabolism of RNA R-HSA-8953854 5.598283e-08 7.252 0 0
mRNA Splicing - Major Pathway R-HSA-72163 6.955623e-08 7.158 0 0
mRNA Splicing R-HSA-72172 1.290525e-07 6.889 0 0
Chromatin organization R-HSA-4839726 4.980744e-06 5.303 0 0
Chromatin modifying enzymes R-HSA-3247509 4.504753e-06 5.346 0 0
DNA Double-Strand Break Repair R-HSA-5693532 8.364037e-06 5.078 0 0
DNA Repair R-HSA-73894 3.657001e-05 4.437 0 0
Cell Cycle R-HSA-1640170 8.223314e-05 4.085 1 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.690528e-04 3.772 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 2.432848e-04 3.614 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 3.133924e-04 3.504 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 4.325922e-04 3.364 0 0
Homology Directed Repair R-HSA-5693538 5.568100e-04 3.254 0 0
Estrogen-dependent gene expression R-HSA-9018519 5.592984e-04 3.252 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 5.832565e-04 3.234 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 7.181564e-04 3.144 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 9.762785e-04 3.010 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.406135e-03 2.852 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.314560e-03 2.881 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.540321e-03 2.812 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 1.645734e-03 2.784 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.709056e-03 2.767 0 0
MTOR signalling R-HSA-165159 2.031652e-03 2.692 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 2.073655e-03 2.683 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 2.366986e-03 2.626 0 0
mTORC1-mediated signalling R-HSA-166208 2.453657e-03 2.610 0 0
Resolution of D-Loop Structures R-HSA-5693537 2.862170e-03 2.543 0 0
Cell Cycle, Mitotic R-HSA-69278 3.037448e-03 2.517 1 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 3.368248e-03 2.473 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 3.861958e-03 2.413 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 3.861958e-03 2.413 0 0
Signaling downstream of RAS mutants R-HSA-9649948 3.861958e-03 2.413 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.663967e-03 2.436 0 0
Signaling by RAS mutants R-HSA-6802949 3.861958e-03 2.413 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.414915e-03 2.467 0 0
Apoptotic execution phase R-HSA-75153 3.861958e-03 2.413 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 4.284638e-03 2.368 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 4.284638e-03 2.368 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 4.284638e-03 2.368 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 4.284638e-03 2.368 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 4.422764e-03 2.354 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 4.420283e-03 2.355 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.494911e-03 2.347 0 0
Nucleotide Excision Repair R-HSA-5696398 4.583169e-03 2.339 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 5.342047e-03 2.272 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 5.480514e-03 2.261 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 7.978387e-03 2.098 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 7.978387e-03 2.098 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 7.978387e-03 2.098 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 7.978387e-03 2.098 0 0
Interaction between L1 and Ankyrins R-HSA-445095 6.973988e-03 2.157 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 7.843876e-03 2.105 0 0
Nuclear RNA decay R-HSA-9930044 6.950453e-03 2.158 0 0
HIV Life Cycle R-HSA-162587 7.214182e-03 2.142 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 6.725651e-03 2.172 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 6.950453e-03 2.158 1 1
Regulation of TP53 Activity through Acetylation R-HSA-6804758 6.950453e-03 2.158 0 0
MITF-M-dependent gene expression R-HSA-9856651 7.613268e-03 2.118 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 9.101482e-03 2.041 0 0
Metabolism of non-coding RNA R-HSA-194441 9.142364e-03 2.039 0 0
snRNP Assembly R-HSA-191859 9.142364e-03 2.039 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 9.142364e-03 2.039 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 9.148611e-03 2.039 0 0
Regulation of TP53 Activity R-HSA-5633007 8.943311e-03 2.049 1 0
HATs acetylate histones R-HSA-3214847 9.329270e-03 2.030 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 9.963794e-03 2.002 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 9.626224e-03 2.017 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 9.626224e-03 2.017 0 0
Nuclear import of Rev protein R-HSA-180746 9.626224e-03 2.017 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.028859e-02 1.988 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 1.033688e-02 1.986 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.046853e-02 1.980 0 0
Cellular response to heat stress R-HSA-3371556 1.149230e-02 1.940 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 1.434318e-02 1.843 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.356235e-02 1.868 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.434318e-02 1.843 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.434318e-02 1.843 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.431524e-02 1.844 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.423096e-02 1.847 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.502759e-02 1.823 0 0
M Phase R-HSA-68886 1.554442e-02 1.808 1 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 1.725193e-02 1.763 0 0
SDK interactions R-HSA-373756 1.761064e-02 1.754 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.870586e-02 1.728 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 1.870586e-02 1.728 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.912939e-02 1.718 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.917463e-02 1.717 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 2.018643e-02 1.695 0 0
Processing of DNA double-strand break ends R-HSA-5693607 2.032251e-02 1.692 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 2.156386e-02 1.666 0 0
DNA Double Strand Break Response R-HSA-5693606 2.175692e-02 1.662 0 0
Epigenetic regulation of gene expression R-HSA-212165 2.239352e-02 1.650 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.229903e-02 1.652 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 2.241544e-02 1.649 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 2.313209e-02 1.636 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 2.326279e-02 1.633 0 0
rRNA processing R-HSA-72312 2.478417e-02 1.606 0 0
Signaling by Hippo R-HSA-2028269 2.512500e-02 1.600 0 0
PKMTs methylate histone lysines R-HSA-3214841 2.537985e-02 1.596 0 0
Cell Cycle Checkpoints R-HSA-69620 2.571154e-02 1.590 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.985376e-02 1.525 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 2.985376e-02 1.525 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 2.819620e-02 1.550 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 3.001153e-02 1.523 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 3.023383e-02 1.520 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 3.099065e-02 1.509 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 3.099065e-02 1.509 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 3.107528e-02 1.508 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 3.401519e-02 1.468 0 0
Unwinding of DNA R-HSA-176974 3.401519e-02 1.468 0 0
G2/M Checkpoints R-HSA-69481 3.309209e-02 1.480 0 0
ESR-mediated signaling R-HSA-8939211 3.161688e-02 1.500 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 3.377912e-02 1.471 1 1
MITF-M-regulated melanocyte development R-HSA-9730414 3.368720e-02 1.473 0 0
Nuclear Envelope Breakdown R-HSA-2980766 3.420684e-02 1.466 0 0
IRS activation R-HSA-74713 3.435616e-02 1.464 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 3.541170e-02 1.451 1 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.556831e-02 1.449 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.556831e-02 1.449 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 3.614319e-02 1.442 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 3.614319e-02 1.442 0 0
Late Phase of HIV Life Cycle R-HSA-162599 3.694221e-02 1.432 0 0
Long-term potentiation R-HSA-9620244 3.915285e-02 1.407 0 0
HDMs demethylate histones R-HSA-3214842 3.915285e-02 1.407 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.087453e-02 1.389 0 0
Mitotic Prometaphase R-HSA-68877 4.156803e-02 1.381 1 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 4.237998e-02 1.373 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 4.340634e-02 1.362 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.435337e-02 1.353 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 4.443215e-02 1.352 0 0
DCC mediated attractive signaling R-HSA-418885 4.443215e-02 1.352 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.579274e-02 1.339 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 4.582359e-02 1.339 0 0
Activation of ATR in response to replication stress R-HSA-176187 4.582359e-02 1.339 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 5.160867e-02 1.287 0 0
Translation initiation complex formation R-HSA-72649 5.194914e-02 1.284 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 4.771598e-02 1.321 0 0
Deubiquitination R-HSA-5688426 4.822211e-02 1.317 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 5.160867e-02 1.287 0 0
Diseases of DNA repair R-HSA-9675135 4.922947e-02 1.308 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.406270e-02 1.267 1 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.406270e-02 1.267 1 0
p75 NTR receptor-mediated signalling R-HSA-193704 5.647791e-02 1.248 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 5.721149e-02 1.243 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 5.721149e-02 1.243 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 5.721149e-02 1.243 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 5.857837e-02 1.232 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 5.857837e-02 1.232 0 0
Mitotic Spindle Checkpoint R-HSA-69618 6.027366e-02 1.220 0 0
NRAGE signals death through JNK R-HSA-193648 6.202180e-02 1.207 0 0
MAP2K and MAPK activation R-HSA-5674135 6.235182e-02 1.205 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 6.323948e-02 1.199 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 6.453593e-02 1.190 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 7.168876e-02 1.145 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 7.329322e-02 1.135 0 0
Dual incision in TC-NER R-HSA-6782135 7.329322e-02 1.135 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 7.329322e-02 1.135 0 0
RNA Polymerase III Transcription R-HSA-74158 7.168876e-02 1.145 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.565793e-02 1.183 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 6.943310e-02 1.158 0 0
AURKA Activation by TPX2 R-HSA-8854518 7.427250e-02 1.129 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.479390e-02 1.126 0 0
Gene expression (Transcription) R-HSA-74160 7.763669e-02 1.110 1 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 9.062339e-02 1.043 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 9.062339e-02 1.043 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 8.078190e-02 1.093 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 8.078190e-02 1.093 0 0
Recycling of eIF2:GDP R-HSA-72731 8.078190e-02 1.093 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 7.936245e-02 1.100 0 0
Ephrin signaling R-HSA-3928664 8.439523e-02 1.074 0 0
Deadenylation of mRNA R-HSA-429947 8.461499e-02 1.073 0 0
mRNA 3'-end processing R-HSA-72187 8.474824e-02 1.072 0 0
Repression of WNT target genes R-HSA-4641265 7.936245e-02 1.100 0 0
DAG and IP3 signaling R-HSA-1489509 9.029938e-02 1.044 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 7.936245e-02 1.100 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 8.525813e-02 1.069 0 0
Membrane Trafficking R-HSA-199991 8.005631e-02 1.097 0 0
HIV Infection R-HSA-162906 9.028429e-02 1.044 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 9.062339e-02 1.043 0 0
Protein ubiquitination R-HSA-8852135 8.014829e-02 1.096 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 7.930461e-02 1.101 0 0
DNA strand elongation R-HSA-69190 9.168980e-02 1.038 0 0
G0 and Early G1 R-HSA-1538133 9.168980e-02 1.038 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 9.187350e-02 1.037 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 9.383033e-02 1.028 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 9.542946e-02 1.020 0 0
PDGFR mutants bind TKIs R-HSA-9674428 9.542946e-02 1.020 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 9.542946e-02 1.020 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 9.542946e-02 1.020 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 9.542946e-02 1.020 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 9.542946e-02 1.020 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 9.542946e-02 1.020 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.013944e-01 0.994 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.059193e-01 0.975 0 0
Amplification of signal from the kinetochores R-HSA-141424 9.681822e-02 1.014 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 9.681822e-02 1.014 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 1.029433e-01 0.987 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.023892e-01 0.990 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.107398e-01 0.956 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.107398e-01 0.956 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.049195e-01 0.979 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.106731e-01 0.956 0 0
Sema4D in semaphorin signaling R-HSA-400685 9.511202e-02 1.022 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.094462e-01 0.961 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.096433e-01 0.960 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 9.698529e-02 1.013 0 0
Signaling by ALK in cancer R-HSA-9700206 9.698529e-02 1.013 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.022912e-01 0.990 1 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 1.013944e-01 0.994 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 1.062713e-01 0.974 0 0
Signaling by ALK R-HSA-201556 9.592317e-02 1.018 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 9.592317e-02 1.018 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.817572e-01 0.741 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.817572e-01 0.741 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.817572e-01 0.741 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.817572e-01 0.741 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.817572e-01 0.741 0 0
UNC93B1 deficiency - HSE R-HSA-5602415 1.817572e-01 0.741 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.817572e-01 0.741 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.817572e-01 0.741 0 0
Impaired BRCA2 translocation to the nucleus R-HSA-9709275 1.817572e-01 0.741 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.817572e-01 0.741 0 0
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198 1.817572e-01 0.741 0 0
Regulation of gap junction activity R-HSA-191650 1.224539e-01 0.912 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 1.224539e-01 0.912 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 1.224539e-01 0.912 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.598509e-01 0.585 0 0
Defective TPMT causes TPMT deficiency R-HSA-5578995 2.598509e-01 0.585 0 0
Defective CD320 causes MMATC R-HSA-3359485 2.598509e-01 0.585 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.598509e-01 0.585 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.598509e-01 0.585 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 2.598509e-01 0.585 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.598509e-01 0.585 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.564929e-01 0.806 0 0
Calcineurin activates NFAT R-HSA-2025928 1.212088e-01 0.916 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 1.920298e-01 0.717 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 1.920298e-01 0.717 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.920298e-01 0.717 0 0
Defective PAPSS2 causes SEMD-PA R-HSA-3560796 3.304955e-01 0.481 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 3.304955e-01 0.481 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 3.304955e-01 0.481 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 3.304955e-01 0.481 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 3.304955e-01 0.481 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.436973e-01 0.843 0 0
2-LTR circle formation R-HSA-164843 1.436973e-01 0.843 0 0
Autointegration results in viral DNA circles R-HSA-177539 2.284690e-01 0.641 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.921949e-01 0.716 1 1
Regulation of PTEN localization R-HSA-8948747 2.653152e-01 0.576 0 0
VLDL clearance R-HSA-8964046 2.653152e-01 0.576 0 0
SOS-mediated signalling R-HSA-112412 2.653152e-01 0.576 0 0
PLC-gamma1 signalling R-HSA-167021 3.944010e-01 0.404 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 3.944010e-01 0.404 0 0
Defective ABCD4 causes MAHCJ R-HSA-5683329 3.944010e-01 0.404 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.944010e-01 0.404 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.944010e-01 0.404 0 0
Defective SLC7A7 causes lysinuric protein intolerance (LPI) R-HSA-5660862 3.944010e-01 0.404 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 1.624066e-01 0.789 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 2.177982e-01 0.662 0 0
Scavenging by Class F Receptors R-HSA-3000484 2.177982e-01 0.662 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.381051e-01 0.860 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 1.381051e-01 0.860 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.180749e-01 0.928 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.180749e-01 0.928 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 3.021590e-01 0.520 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 3.021590e-01 0.520 0 0
Formation of annular gap junctions R-HSA-196025 3.021590e-01 0.520 0 0
Notch-HLH transcription pathway R-HSA-350054 1.534367e-01 0.814 0 0
HIV elongation arrest and recovery R-HSA-167287 1.305011e-01 0.884 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.305011e-01 0.884 0 0
PKA activation R-HSA-163615 2.019181e-01 0.695 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 1.694375e-01 0.771 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 1.694375e-01 0.771 0 0
RAF activation R-HSA-5673000 1.223990e-01 0.912 0 0
Activation of the pre-replicative complex R-HSA-68962 1.571160e-01 0.804 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.226498e-01 0.652 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.386657e-01 0.470 0 0
ARMS-mediated activation R-HSA-170984 3.386657e-01 0.470 0 0
Gap junction degradation R-HSA-190873 3.386657e-01 0.470 0 0
WNT mediated activation of DVL R-HSA-201688 3.386657e-01 0.470 1 1
ALK mutants bind TKIs R-HSA-9700645 3.386657e-01 0.470 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 4.522100e-01 0.345 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 4.522100e-01 0.345 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 4.522100e-01 0.345 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 2.977619e-01 0.526 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.655812e-01 0.576 0 0
Regulation of the apoptosome activity R-HSA-9627069 3.745640e-01 0.426 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.745640e-01 0.426 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 3.249045e-01 0.488 0 0
Phosphorylation of the APC/C R-HSA-176412 3.249045e-01 0.488 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 3.249045e-01 0.488 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 1.970092e-01 0.706 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.205079e-01 0.919 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 1.799158e-01 0.745 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 1.799158e-01 0.745 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 2.575478e-01 0.589 0 0
Formation of the Early Elongation Complex R-HSA-113418 2.575478e-01 0.589 0 0
Centrosome maturation R-HSA-380287 1.361777e-01 0.866 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 3.098441e-01 0.509 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 3.520421e-01 0.453 0 0
NrCAM interactions R-HSA-447038 5.045039e-01 0.297 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 5.045039e-01 0.297 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 3.790453e-01 0.421 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 3.790453e-01 0.421 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 3.790453e-01 0.421 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.828027e-01 0.738 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 3.547316e-01 0.450 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 4.437174e-01 0.353 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.437174e-01 0.353 0 0
Meiotic synapsis R-HSA-1221632 2.721570e-01 0.565 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 4.057986e-01 0.392 0 0
PKA activation in glucagon signalling R-HSA-164378 4.057986e-01 0.392 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 4.057986e-01 0.392 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 3.006291e-01 0.522 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 3.338742e-01 0.476 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 3.338742e-01 0.476 0 0
Separation of Sister Chromatids R-HSA-2467813 1.582117e-01 0.801 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 4.321995e-01 0.364 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 4.321995e-01 0.364 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 4.766732e-01 0.322 0 0
Polymerase switching R-HSA-69091 4.766732e-01 0.322 0 0
Leading Strand Synthesis R-HSA-69109 4.766732e-01 0.322 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 5.518083e-01 0.258 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 5.518083e-01 0.258 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 5.518083e-01 0.258 0 0
Loss-of-function mutations in DBT cause MSUD2 R-HSA-9865113 5.518083e-01 0.258 0 0
Loss-of-function mutations in DLD cause MSUD3/DLDD R-HSA-9907570 5.518083e-01 0.258 0 0
Signaling by MAPK mutants R-HSA-9652817 5.518083e-01 0.258 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 3.689827e-01 0.433 0 0
HIV Transcription Initiation R-HSA-167161 3.689827e-01 0.433 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 3.689827e-01 0.433 0 0
Dual Incision in GG-NER R-HSA-5696400 3.930541e-01 0.406 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.218587e-01 0.375 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 3.547506e-01 0.450 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 3.744069e-01 0.427 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 4.042210e-01 0.393 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 3.686842e-01 0.433 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 4.835969e-01 0.316 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 4.835969e-01 0.316 0 0
Lagging Strand Synthesis R-HSA-69186 4.835969e-01 0.316 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.126478e-01 0.384 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 4.393067e-01 0.357 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.706633e-01 0.431 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 5.084492e-01 0.294 0 0
VLDL assembly R-HSA-8866423 5.945992e-01 0.226 0 0
Chylomicron clearance R-HSA-8964026 5.945992e-01 0.226 0 0
STAT5 Activation R-HSA-9645135 5.945992e-01 0.226 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 5.945992e-01 0.226 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.945992e-01 0.226 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 5.945992e-01 0.226 0 0
H139Hfs13* PPM1K causes a mild variant of MSUD R-HSA-9912529 5.945992e-01 0.226 0 0
Defective CHST3 causes SEDCJD R-HSA-3595172 5.945992e-01 0.226 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 5.945992e-01 0.226 0 0
Branched-chain ketoacid dehydrogenase kinase deficiency R-HSA-9912481 5.945992e-01 0.226 0 0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD R-HSA-9865125 5.945992e-01 0.226 0 0
Recycling pathway of L1 R-HSA-437239 4.739818e-01 0.324 0 0
FGFR2 alternative splicing R-HSA-6803529 5.326594e-01 0.274 0 0
Processive synthesis on the lagging strand R-HSA-69183 5.679764e-01 0.246 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 5.679764e-01 0.246 0 0
Translesion synthesis by REV1 R-HSA-110312 5.679764e-01 0.246 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 5.574333e-01 0.254 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.957405e-01 0.225 0 0
Translesion synthesis by POLI R-HSA-5656121 5.957405e-01 0.225 0 0
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782 6.333070e-01 0.198 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 6.333070e-01 0.198 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 6.333070e-01 0.198 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 6.333070e-01 0.198 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 6.333070e-01 0.198 0 0
Defective CHSY1 causes TPBS R-HSA-3595177 6.333070e-01 0.198 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 6.333070e-01 0.198 0 0
Regulation of PTEN stability and activity R-HSA-8948751 5.733858e-01 0.242 1 1
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 5.733858e-01 0.242 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 6.044065e-01 0.219 0 0
Translesion synthesis by POLK R-HSA-5655862 6.221437e-01 0.206 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 6.194462e-01 0.208 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 6.295851e-01 0.201 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 6.453803e-01 0.190 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 6.427729e-01 0.192 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 6.427729e-01 0.192 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 6.471927e-01 0.189 0 0
ALKBH3 mediated reversal of alkylation damage R-HSA-112126 6.683210e-01 0.175 0 0
Type I hemidesmosome assembly R-HSA-446107 6.683210e-01 0.175 0 0
RSK activation R-HSA-444257 6.683210e-01 0.175 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 6.683210e-01 0.175 0 0
phospho-PLA2 pathway R-HSA-111995 6.683210e-01 0.175 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 6.683210e-01 0.175 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 6.683210e-01 0.175 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 6.683210e-01 0.175 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 6.624567e-01 0.179 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 6.624567e-01 0.179 0 0
Transcription of the HIV genome R-HSA-167172 1.479581e-01 0.830 0 0
Signaling by EGFR in Cancer R-HSA-1643713 6.222923e-01 0.206 0 0
Downstream signal transduction R-HSA-186763 5.082688e-01 0.294 0 0
HIV Transcription Elongation R-HSA-167169 1.970092e-01 0.706 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 1.571160e-01 0.804 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.437174e-01 0.353 0 0
mRNA Capping R-HSA-72086 2.763844e-01 0.558 0 0
Formation of apoptosome R-HSA-111458 3.745640e-01 0.426 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 3.996051e-01 0.398 0 0
Post NMDA receptor activation events R-HSA-438064 1.739410e-01 0.760 0 0
Cellular response to starvation R-HSA-9711097 4.049810e-01 0.393 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.739818e-01 0.324 0 0
HSF1-dependent transactivation R-HSA-3371571 1.439499e-01 0.842 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 1.970092e-01 0.706 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 2.324232e-01 0.634 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.680026e-01 0.775 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.205079e-01 0.919 0 0
Integration of provirus R-HSA-162592 1.921949e-01 0.716 0 0
Receptor Mediated Mitophagy R-HSA-8934903 3.745640e-01 0.426 1 1
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 2.954884e-01 0.529 0 0
EPH-Ephrin signaling R-HSA-2682334 2.301485e-01 0.638 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 4.393067e-01 0.357 0 0
Signaling by PDGF R-HSA-186797 5.536591e-01 0.257 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 2.707570e-01 0.567 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 2.977619e-01 0.526 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.798587e-01 0.745 0 0
COPI-mediated anterograde transport R-HSA-6807878 1.937866e-01 0.713 0 0
PCP/CE pathway R-HSA-4086400 4.942575e-01 0.306 0 0
Insulin receptor recycling R-HSA-77387 6.624567e-01 0.179 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 6.650673e-01 0.177 0 0
Generation of second messenger molecules R-HSA-202433 5.081179e-01 0.294 0 0
PERK regulates gene expression R-HSA-381042 2.486929e-01 0.604 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 2.818321e-01 0.550 0 0
UCH proteinases R-HSA-5689603 6.050582e-01 0.218 0 0
Meiosis R-HSA-1500620 3.331933e-01 0.477 0 0
G-protein mediated events R-HSA-112040 2.257058e-01 0.646 0 0
PTEN Regulation R-HSA-6807070 1.118143e-01 0.952 1 0
Activated NTRK3 signals through PI3K R-HSA-9603381 2.653152e-01 0.576 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 3.021590e-01 0.520 0 0
Regulation of CDH11 function R-HSA-9762292 3.745640e-01 0.426 0 0
PI3K/AKT activation R-HSA-198203 3.745640e-01 0.426 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 1.834868e-01 0.736 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 4.096378e-01 0.388 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 5.326594e-01 0.274 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.957405e-01 0.225 0 0
Integrin signaling R-HSA-354192 5.492488e-01 0.260 0 0
Chaperone Mediated Autophagy R-HSA-9613829 4.057986e-01 0.392 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.151978e-01 0.939 0 0
PIP3 activates AKT signaling R-HSA-1257604 4.950645e-01 0.305 1 0
Clathrin-mediated endocytosis R-HSA-8856828 2.691727e-01 0.570 0 0
EPHB-mediated forward signaling R-HSA-3928662 4.217997e-01 0.375 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 4.522100e-01 0.345 0 0
PLC beta mediated events R-HSA-112043 1.610563e-01 0.793 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 5.045039e-01 0.297 0 0
NF-kB is activated and signals survival R-HSA-209560 4.437174e-01 0.353 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 4.766732e-01 0.322 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 4.766732e-01 0.322 0 0
Signaling by MST1 R-HSA-8852405 5.518083e-01 0.258 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.364689e-01 0.626 1 0
Amino acids regulate mTORC1 R-HSA-9639288 5.733858e-01 0.242 0 0
Ca-dependent events R-HSA-111996 1.345758e-01 0.871 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.437174e-01 0.353 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 3.513937e-01 0.454 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 6.221437e-01 0.206 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.870901e-01 0.231 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 4.043368e-01 0.393 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 2.735501e-01 0.563 0 0
Myogenesis R-HSA-525793 3.996051e-01 0.398 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 4.766732e-01 0.322 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.447970e-01 0.352 0 0
RNA Polymerase I Transcription R-HSA-73864 4.942575e-01 0.306 0 0
Degradation of DVL R-HSA-4641258 6.431217e-01 0.192 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 6.427729e-01 0.192 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 6.471927e-01 0.189 0 0
CaM pathway R-HSA-111997 1.454386e-01 0.837 0 0
Synthesis of DNA R-HSA-69239 4.165424e-01 0.380 0 0
Calmodulin induced events R-HSA-111933 1.454386e-01 0.837 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 2.486929e-01 0.604 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 2.498552e-01 0.602 0 0
L1CAM interactions R-HSA-373760 4.311432e-01 0.365 1 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 2.301752e-01 0.638 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 1.564929e-01 0.806 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 1.624066e-01 0.789 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 2.440460e-01 0.613 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.019181e-01 0.695 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 1.345758e-01 0.871 0 0
Formation of the posterior neural plate R-HSA-9832991 4.096378e-01 0.388 0 0
Activation of AKT2 R-HSA-165158 5.045039e-01 0.297 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 3.790453e-01 0.421 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 4.437174e-01 0.353 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.304837e-01 0.637 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 5.080161e-01 0.294 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 5.957405e-01 0.225 0 0
Killing mechanisms R-HSA-9664420 5.957405e-01 0.225 0 0
PTK6 Expression R-HSA-8849473 6.333070e-01 0.198 0 0
LDL remodeling R-HSA-8964041 6.333070e-01 0.198 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 6.010228e-01 0.221 0 0
MET promotes cell motility R-HSA-8875878 6.602708e-01 0.180 0 0
Mitotic Anaphase R-HSA-68882 1.581764e-01 0.801 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.698476e-01 0.244 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 5.079611e-01 0.294 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.705164e-01 0.768 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.634114e-01 0.787 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 6.388548e-01 0.195 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.130770e-01 0.947 0 0
Prolonged ERK activation events R-HSA-169893 5.957405e-01 0.225 0 0
Acyl chain remodelling of PS R-HSA-1482801 2.032317e-01 0.692 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.541914e-01 0.812 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 5.233803e-01 0.281 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 5.233803e-01 0.281 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 5.233803e-01 0.281 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 5.233803e-01 0.281 0 0
Signaling by VEGF R-HSA-194138 3.342711e-01 0.476 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 3.772070e-01 0.423 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.047747e-01 0.689 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.209123e-01 0.656 0 0
Mitophagy R-HSA-5205647 5.883619e-01 0.230 1 0
Selective autophagy R-HSA-9663891 6.363930e-01 0.196 1 0
Autophagy R-HSA-9612973 5.757521e-01 0.240 1 0
Signaling by WNT R-HSA-195721 6.569786e-01 0.182 1 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.921949e-01 0.716 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 1.534367e-01 0.814 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 5.045039e-01 0.297 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 5.045039e-01 0.297 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 2.859738e-01 0.544 0 0
Switching of origins to a post-replicative state R-HSA-69052 2.985517e-01 0.525 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 3.594919e-01 0.444 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 4.666467e-01 0.331 0 0
Diseases of mitotic cell cycle R-HSA-9675126 5.289772e-01 0.277 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 4.843873e-01 0.315 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 6.471927e-01 0.189 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 6.683210e-01 0.175 0 0
GPER1 signaling R-HSA-9634597 6.607456e-01 0.180 0 0
DNA Replication Pre-Initiation R-HSA-69002 6.676204e-01 0.175 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 3.996051e-01 0.398 0 0
Signal attenuation R-HSA-74749 1.436973e-01 0.843 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.143662e-01 0.942 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 2.655812e-01 0.576 0 0
HSF1 activation R-HSA-3371511 6.254127e-01 0.204 0 0
TCF dependent signaling in response to WNT R-HSA-201681 5.532837e-01 0.257 1 0
Regulation of CDH1 Function R-HSA-9764561 3.298757e-01 0.482 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.191914e-01 0.659 0 0
Macroautophagy R-HSA-1632852 5.183348e-01 0.285 1 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.386657e-01 0.470 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.732968e-01 0.563 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.925917e-01 0.534 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 6.453803e-01 0.190 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 5.214718e-01 0.283 0 0
Cilium Assembly R-HSA-5617833 5.261867e-01 0.279 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 2.177982e-01 0.662 0 0
p75NTR signals via NF-kB R-HSA-193639 5.679764e-01 0.246 0 0
Semaphorin interactions R-HSA-373755 2.865206e-01 0.543 0 0
Apoptotic factor-mediated response R-HSA-111471 4.057986e-01 0.392 0 0
Axon guidance R-HSA-422475 3.491806e-01 0.457 1 0
S Phase R-HSA-69242 1.698533e-01 0.770 0 0
Signaling by Nuclear Receptors R-HSA-9006931 4.838898e-01 0.315 0 0
Vesicle-mediated transport R-HSA-5653656 5.669262e-01 0.246 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.954884e-01 0.529 0 0
Nervous system development R-HSA-9675108 2.939238e-01 0.532 1 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 1.212088e-01 0.916 0 0
Regulation of cortical dendrite branching R-HSA-8985801 3.304955e-01 0.481 0 0
Bicarbonate transporters R-HSA-425381 1.674278e-01 0.776 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 1.438196e-01 0.842 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 3.944010e-01 0.404 0 0
MET interacts with TNS proteins R-HSA-8875513 3.944010e-01 0.404 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 3.944010e-01 0.404 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 2.019181e-01 0.695 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 4.522100e-01 0.345 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 4.522100e-01 0.345 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 2.209123e-01 0.656 0 0
Metalloprotease DUBs R-HSA-5689901 2.209123e-01 0.656 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 2.655812e-01 0.576 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.680026e-01 0.775 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 2.165041e-01 0.665 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.610563e-01 0.793 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.610563e-01 0.793 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 2.763844e-01 0.558 0 0
Disorders of Developmental Biology R-HSA-9675151 3.520421e-01 0.453 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 5.045039e-01 0.297 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.437174e-01 0.353 0 0
Sodium/Calcium exchangers R-HSA-425561 4.437174e-01 0.353 0 0
ERKs are inactivated R-HSA-202670 4.437174e-01 0.353 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.772070e-01 0.423 0 0
Cam-PDE 1 activation R-HSA-111957 5.518083e-01 0.258 0 0
PDE3B signalling R-HSA-165160 5.518083e-01 0.258 0 0
PKB-mediated events R-HSA-109703 5.518083e-01 0.258 0 0
TBC/RABGAPs R-HSA-8854214 4.042210e-01 0.393 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.439057e-01 0.353 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 5.388581e-01 0.269 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.679764e-01 0.246 0 0
Orc1 removal from chromatin R-HSA-68949 5.574333e-01 0.254 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 5.789789e-01 0.237 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 6.333070e-01 0.198 0 0
Disinhibition of SNARE formation R-HSA-114516 6.333070e-01 0.198 0 0
Smooth Muscle Contraction R-HSA-445355 5.733858e-01 0.242 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 6.114978e-01 0.214 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.109088e-01 0.676 0 0
Early Phase of HIV Life Cycle R-HSA-162594 1.234921e-01 0.908 0 0
Signaling by NOTCH1 R-HSA-1980143 4.666467e-01 0.331 0 0
FGFR1 mutant receptor activation R-HSA-1839124 2.009756e-01 0.697 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 6.096678e-01 0.215 0 0
Ub-specific processing proteases R-HSA-5689880 2.939733e-01 0.532 0 0
Response of endothelial cells to shear stress R-HSA-9860931 6.026711e-01 0.220 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.547316e-01 0.450 0 0
Cell junction organization R-HSA-446728 1.947568e-01 0.711 1 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.538349e-01 0.451 0 0
Cell-cell junction organization R-HSA-421270 1.517275e-01 0.819 1 0
Uptake and function of anthrax toxins R-HSA-5210891 1.818047e-01 0.740 0 0
Adherens junctions interactions R-HSA-418990 1.245996e-01 0.904 1 0
Transport of RCbl within the body R-HSA-9758890 1.674278e-01 0.776 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 3.790453e-01 0.421 0 0
Cellular Senescence R-HSA-2559583 3.522100e-01 0.453 0 0
Netrin-1 signaling R-HSA-373752 1.564640e-01 0.806 0 0
Cell-Cell communication R-HSA-1500931 1.199737e-01 0.921 1 0
DNA Damage Reversal R-HSA-73942 2.977619e-01 0.526 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.322264e-01 0.479 0 0
Assembly of the pre-replicative complex R-HSA-68867 5.831401e-01 0.234 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 1.212088e-01 0.916 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 1.674278e-01 0.776 0 0
tRNA processing in the nucleus R-HSA-6784531 1.711416e-01 0.767 0 0
Signaling by FGFR1 in disease R-HSA-5655302 2.251581e-01 0.648 0 0
Kinesins R-HSA-983189 3.744069e-01 0.427 0 0
NRIF signals cell death from the nucleus R-HSA-205043 5.388581e-01 0.269 0 0
Diseases of Immune System R-HSA-5260271 5.081179e-01 0.294 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 5.081179e-01 0.294 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 5.663125e-01 0.247 0 0
Mitotic Prophase R-HSA-68875 1.967808e-01 0.706 0 0
Ion homeostasis R-HSA-5578775 4.607637e-01 0.337 0 0
Signal Transduction R-HSA-162582 6.050173e-01 0.218 1 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.019181e-01 0.695 0 0
Muscarinic acetylcholine receptors R-HSA-390648 5.045039e-01 0.297 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 3.790453e-01 0.421 0 0
HDACs deacetylate histones R-HSA-3214815 3.007007e-01 0.522 0 0
Pervasive developmental disorders R-HSA-9005895 4.766732e-01 0.322 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 4.766732e-01 0.322 0 0
Disorders of Nervous System Development R-HSA-9697154 4.766732e-01 0.322 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.894458e-01 0.310 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 6.427729e-01 0.192 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.763898e-01 0.754 0 0
Nephrin family interactions R-HSA-373753 4.581582e-01 0.339 0 0
FLT3 signaling in disease R-HSA-9682385 4.320673e-01 0.364 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 3.386657e-01 0.470 0 0
TGFBR3 expression R-HSA-9839394 2.032317e-01 0.692 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 5.045039e-01 0.297 0 0
Rab regulation of trafficking R-HSA-9007101 5.525146e-01 0.258 0 0
Neurexins and neuroligins R-HSA-6794361 3.965151e-01 0.402 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 5.084492e-01 0.294 0 0
Signaling by ROBO receptors R-HSA-376176 3.837341e-01 0.416 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.697154e-01 0.569 0 0
Protein-protein interactions at synapses R-HSA-6794362 2.293310e-01 0.640 0 0
RMTs methylate histone arginines R-HSA-3214858 4.217997e-01 0.375 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 5.082688e-01 0.294 0 0
ER to Golgi Anterograde Transport R-HSA-199977 4.885350e-01 0.311 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.436973e-01 0.843 0 0
Ovarian tumor domain proteases R-HSA-5689896 6.431217e-01 0.192 0 0
Mismatch Repair R-HSA-5358508 4.057986e-01 0.392 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 4.656897e-01 0.332 0 0
Elastic fibre formation R-HSA-1566948 4.705236e-01 0.327 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 6.308893e-01 0.200 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.205375e-01 0.919 1 0
Mitotic G1 phase and G1/S transition R-HSA-453279 3.827051e-01 0.417 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.212088e-01 0.916 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 2.284690e-01 0.641 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 3.745640e-01 0.426 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 5.045039e-01 0.297 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 3.547316e-01 0.450 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.437174e-01 0.353 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 5.518083e-01 0.258 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 5.518083e-01 0.258 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.518083e-01 0.258 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 3.744069e-01 0.427 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 5.233803e-01 0.281 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 6.222923e-01 0.206 0 0
TGFBR3 PTM regulation R-HSA-9839383 6.683210e-01 0.175 0 0
G2/M Transition R-HSA-69275 3.228012e-01 0.491 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.391772e-01 0.470 0 0
Heme signaling R-HSA-9707616 5.536591e-01 0.257 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 4.656897e-01 0.332 0 0
Formation of definitive endoderm R-HSA-9823730 4.581582e-01 0.339 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 5.265091e-01 0.279 0 0
Signaling by ERBB2 R-HSA-1227986 5.233803e-01 0.281 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.536591e-01 0.257 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 1.920298e-01 0.717 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 2.440460e-01 0.613 0 0
RNA Polymerase II Transcription R-HSA-73857 4.477422e-01 0.349 1 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 3.734467e-01 0.428 0 0
Host Interactions of HIV factors R-HSA-162909 3.144456e-01 0.502 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 1.153200e-01 0.938 0 0
Other interleukin signaling R-HSA-449836 4.321995e-01 0.364 0 0
RET signaling R-HSA-8853659 6.254127e-01 0.204 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 2.009756e-01 0.697 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.875918e-01 0.541 0 0
PECAM1 interactions R-HSA-210990 4.096378e-01 0.388 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.954884e-01 0.529 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 3.538349e-01 0.451 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 3.547506e-01 0.450 0 0
ERK/MAPK targets R-HSA-198753 4.835969e-01 0.316 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 5.945992e-01 0.226 0 0
Inositol phosphate metabolism R-HSA-1483249 1.258339e-01 0.900 0 0
Spry regulation of FGF signaling R-HSA-1295596 5.679764e-01 0.246 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.026977e-01 0.693 0 0
G alpha (12/13) signalling events R-HSA-416482 2.501805e-01 0.602 0 0
Signaling by TGFBR3 R-HSA-9839373 3.006291e-01 0.522 0 0
Apoptosis R-HSA-109581 2.033400e-01 0.692 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 1.541914e-01 0.812 0 0
Signaling by FGFR in disease R-HSA-1226099 4.387579e-01 0.358 0 0
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis R-HSA-9708296 3.304955e-01 0.481 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 2.653152e-01 0.576 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.143662e-01 0.942 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.386657e-01 0.470 0 0
Dopamine receptors R-HSA-390651 4.522100e-01 0.345 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 3.745640e-01 0.426 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 2.875918e-01 0.541 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 5.045039e-01 0.297 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 5.045039e-01 0.297 0 0
Metal ion SLC transporters R-HSA-425410 3.322264e-01 0.479 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 5.518083e-01 0.258 0 0
CREB phosphorylation R-HSA-199920 5.945992e-01 0.226 0 0
Trafficking of AMPA receptors R-HSA-399719 5.082688e-01 0.294 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.679764e-01 0.246 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 6.333070e-01 0.198 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 6.333070e-01 0.198 0 0
Netrin mediated repulsion signals R-HSA-418886 6.333070e-01 0.198 0 0
Potential therapeutics for SARS R-HSA-9679191 6.156411e-01 0.211 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 6.683210e-01 0.175 0 0
Sodium/Proton exchangers R-HSA-425986 6.683210e-01 0.175 0 0
G1/S Transition R-HSA-69206 5.403575e-01 0.267 0 0
Zinc transporters R-HSA-435354 2.707570e-01 0.567 0 0
Interleukin-7 signaling R-HSA-1266695 2.032317e-01 0.692 0 0
Sensory processing of sound R-HSA-9659379 5.079212e-01 0.294 0 0
Signaling by TGFB family members R-HSA-9006936 3.354498e-01 0.474 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 3.322514e-01 0.479 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 3.689827e-01 0.433 0 0
Death Receptor Signaling R-HSA-73887 1.517566e-01 0.819 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 3.062025e-01 0.514 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 3.338742e-01 0.476 0 0
Programmed Cell Death R-HSA-5357801 4.086461e-01 0.389 0 0
Toxicity of botulinum toxin type C (botC) R-HSA-5250971 1.564929e-01 0.806 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 1.920298e-01 0.717 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 2.653152e-01 0.576 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 2.653152e-01 0.576 0 0
Expression and Processing of Neurotrophins R-HSA-9036866 3.944010e-01 0.404 0 0
NGF processing R-HSA-167060 3.944010e-01 0.404 0 0
Signal regulatory protein family interactions R-HSA-391160 2.707570e-01 0.567 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.386657e-01 0.470 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.977619e-01 0.526 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.977619e-01 0.526 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.799158e-01 0.745 0 0
LGI-ADAM interactions R-HSA-5682910 4.096378e-01 0.388 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 5.045039e-01 0.297 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 5.518083e-01 0.258 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.324776e-01 0.478 0 0
Basigin interactions R-HSA-210991 4.835969e-01 0.316 0 0
HDL clearance R-HSA-8964011 5.945992e-01 0.226 0 0
Signaling by EGFR R-HSA-177929 4.607637e-01 0.337 0 0
Formation of the anterior neural plate R-HSA-9823739 5.679764e-01 0.246 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 6.683210e-01 0.175 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 6.650673e-01 0.177 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 2.390374e-01 0.622 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 6.427729e-01 0.192 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.835356e-01 0.547 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 2.019181e-01 0.695 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.118143e-01 0.952 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 5.326594e-01 0.274 0 0
Gene Silencing by RNA R-HSA-211000 5.313170e-01 0.275 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.438196e-01 0.842 0 0
Josephin domain DUBs R-HSA-5689877 3.745640e-01 0.426 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 4.766269e-01 0.322 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 6.683210e-01 0.175 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.652973e-01 0.782 0 0
Neurofascin interactions R-HSA-447043 5.945992e-01 0.226 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 5.945992e-01 0.226 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 6.683210e-01 0.175 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 6.683210e-01 0.175 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 6.602708e-01 0.180 0 0
Specification of the neural plate border R-HSA-9834899 4.321995e-01 0.364 0 0
Regulation of TP53 Degradation R-HSA-6804757 6.254127e-01 0.204 0 0
IRE1alpha activates chaperones R-HSA-381070 2.202989e-01 0.657 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 6.333070e-01 0.198 0 0
Insulin processing R-HSA-264876 6.427729e-01 0.192 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 4.491548e-01 0.348 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 5.492488e-01 0.260 0 0
Signaling by Leptin R-HSA-2586552 3.745640e-01 0.426 0 0
STING mediated induction of host immune responses R-HSA-1834941 4.321995e-01 0.364 0 0
Specification of primordial germ cells R-HSA-9827857 6.471927e-01 0.189 0 0
Synthesis and processing of ENV and VPU R-HSA-171286 3.304955e-01 0.481 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 5.679764e-01 0.246 0 0
Interleukin-37 signaling R-HSA-9008059 1.571160e-01 0.804 0 0
Interleukin-12 signaling R-HSA-9020591 6.050582e-01 0.218 0 0
Platelet sensitization by LDL R-HSA-432142 6.709054e-01 0.173 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 6.709054e-01 0.173 0 0
GAB1 signalosome R-HSA-180292 6.709054e-01 0.173 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 6.709054e-01 0.173 0 0
DNA Damage Bypass R-HSA-73893 6.756732e-01 0.170 0 0
Degradation of CDH1 R-HSA-9766229 6.756732e-01 0.170 0 0
Plasma lipoprotein clearance R-HSA-8964043 6.768525e-01 0.170 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 6.768525e-01 0.170 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 6.768525e-01 0.170 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 6.777268e-01 0.169 0 0
TCR signaling R-HSA-202403 6.778329e-01 0.169 0 0
Cellular responses to stress R-HSA-2262752 6.790046e-01 0.168 1 0
Platelet calcium homeostasis R-HSA-418360 6.813407e-01 0.167 0 0
DARPP-32 events R-HSA-180024 6.813407e-01 0.167 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 6.895146e-01 0.161 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.900812e-01 0.161 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 6.900812e-01 0.161 0 0
Aggrephagy R-HSA-9646399 6.928623e-01 0.159 0 0
Attenuation phase R-HSA-3371568 6.928623e-01 0.159 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.933085e-01 0.159 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 6.933085e-01 0.159 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.933085e-01 0.159 0 0
The NLRP3 inflammasome R-HSA-844456 6.933085e-01 0.159 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 6.943724e-01 0.158 0 0
PI Metabolism R-HSA-1483255 6.953435e-01 0.158 0 0
Cellular responses to stimuli R-HSA-8953897 6.957917e-01 0.158 1 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 6.994268e-01 0.155 0 0
DAP12 signaling R-HSA-2424491 6.994268e-01 0.155 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 6.994268e-01 0.155 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 6.994268e-01 0.155 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 6.994268e-01 0.155 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 6.999935e-01 0.155 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 6.999935e-01 0.155 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 6.999935e-01 0.155 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 6.999935e-01 0.155 0 0
Lipophagy R-HSA-9613354 6.999935e-01 0.155 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 6.999935e-01 0.155 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 6.999935e-01 0.155 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.999935e-01 0.155 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 6.999935e-01 0.155 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 6.999935e-01 0.155 0 0
GP1b-IX-V activation signalling R-HSA-430116 6.999935e-01 0.155 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 6.999935e-01 0.155 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 6.999935e-01 0.155 0 0
Regulated proteolysis of p75NTR R-HSA-193692 6.999935e-01 0.155 0 0
Interleukin-1 processing R-HSA-448706 6.999935e-01 0.155 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 6.999935e-01 0.155 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 7.001966e-01 0.155 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 7.024523e-01 0.153 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.027028e-01 0.153 0 0
Reproduction R-HSA-1474165 7.027960e-01 0.153 0 0
MAPK family signaling cascades R-HSA-5683057 7.029000e-01 0.153 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 7.144358e-01 0.146 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 7.144358e-01 0.146 0 0
Co-inhibition by CTLA4 R-HSA-389513 7.144358e-01 0.146 0 0
Signal transduction by L1 R-HSA-445144 7.144358e-01 0.146 1 1
Signaling by NODAL R-HSA-1181150 7.144358e-01 0.146 0 0
Opioid Signalling R-HSA-111885 7.153750e-01 0.145 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 7.163532e-01 0.145 1 1
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.167213e-01 0.145 0 0
Molecules associated with elastic fibres R-HSA-2129379 7.167213e-01 0.145 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 7.177818e-01 0.144 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 7.184601e-01 0.144 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 7.231611e-01 0.141 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 7.231611e-01 0.141 0 0
IGF1R signaling cascade R-HSA-2428924 7.272194e-01 0.138 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 7.286432e-01 0.137 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 7.286432e-01 0.137 0 0
Folding of actin by CCT/TriC R-HSA-390450 7.286432e-01 0.137 0 0
Binding and entry of HIV virion R-HSA-173107 7.286432e-01 0.137 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 7.286432e-01 0.137 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 7.286432e-01 0.137 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 7.286432e-01 0.137 0 0
Pexophagy R-HSA-9664873 7.286432e-01 0.137 0 0
CASP4 inflammasome assembly R-HSA-9948001 7.286432e-01 0.137 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 7.286432e-01 0.137 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 7.305010e-01 0.136 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 7.309192e-01 0.136 0 0
DNA Replication R-HSA-69306 7.323039e-01 0.135 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 7.332337e-01 0.135 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 7.343268e-01 0.134 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 7.343268e-01 0.134 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 7.343268e-01 0.134 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 7.343268e-01 0.134 0 0
Formation of a pool of free 40S subunits R-HSA-72689 7.344418e-01 0.134 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 7.345397e-01 0.134 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 7.390463e-01 0.131 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 7.400620e-01 0.131 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 7.436075e-01 0.129 0 0
Chaperonin-mediated protein folding R-HSA-390466 7.451778e-01 0.128 1 0
Interleukin-12 family signaling R-HSA-447115 7.451778e-01 0.128 0 0
G-protein beta:gamma signalling R-HSA-397795 7.489770e-01 0.126 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 7.511813e-01 0.124 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 7.530247e-01 0.123 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 7.530247e-01 0.123 0 0
Serine metabolism R-HSA-977347 7.530247e-01 0.123 0 0
ChREBP activates metabolic gene expression R-HSA-163765 7.545586e-01 0.122 0 0
Chylomicron assembly R-HSA-8963888 7.545586e-01 0.122 0 0
Signaling by APC mutants R-HSA-4839744 7.545586e-01 0.122 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 7.545586e-01 0.122 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 7.545586e-01 0.122 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 7.545586e-01 0.122 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 7.545586e-01 0.122 0 0
Ionotropic activity of kainate receptors R-HSA-451306 7.545586e-01 0.122 0 0
vRNP Assembly R-HSA-192905 7.545586e-01 0.122 0 0
Synthesis of PI R-HSA-1483226 7.545586e-01 0.122 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 7.545586e-01 0.122 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 7.545586e-01 0.122 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.545586e-01 0.122 0 0
Dissolution of Fibrin Clot R-HSA-75205 7.545586e-01 0.122 0 0
Signaling by NOTCH3 R-HSA-9012852 7.558491e-01 0.122 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 7.639667e-01 0.117 0 0
Miscellaneous transport and binding events R-HSA-5223345 7.639667e-01 0.117 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.676474e-01 0.115 0 0
TNF signaling R-HSA-75893 7.676474e-01 0.115 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 7.676474e-01 0.115 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 7.693172e-01 0.114 0 0
LDL clearance R-HSA-8964038 7.705760e-01 0.113 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 7.705760e-01 0.113 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 7.705760e-01 0.113 0 0
Influenza Infection R-HSA-168255 7.711988e-01 0.113 0 0
Base Excision Repair R-HSA-73884 7.741366e-01 0.111 0 0
Signaling by NTRKs R-HSA-166520 7.763644e-01 0.110 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 7.769694e-01 0.110 0 0
Nucleosome assembly R-HSA-774815 7.769694e-01 0.110 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 7.769694e-01 0.110 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 7.780003e-01 0.109 0 0
DS-GAG biosynthesis R-HSA-2022923 7.780003e-01 0.109 0 0
Scavenging by Class H Receptors R-HSA-3000497 7.780003e-01 0.109 0 0
Activation of RAC1 R-HSA-428540 7.780003e-01 0.109 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 7.780003e-01 0.109 0 0
Signaling by GSK3beta mutants R-HSA-5339716 7.780003e-01 0.109 0 0
Signaling by AXIN mutants R-HSA-4839735 7.780003e-01 0.109 0 0
Signaling by AMER1 mutants R-HSA-4839748 7.780003e-01 0.109 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 7.780003e-01 0.109 0 0
Uptake of dietary cobalamins into enterocytes R-HSA-9758881 7.780003e-01 0.109 0 0
Signaling by NOTCH2 R-HSA-1980145 7.782204e-01 0.109 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 7.782204e-01 0.109 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 7.782204e-01 0.109 0 0
NOD1/2 Signaling Pathway R-HSA-168638 7.782204e-01 0.109 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 7.782204e-01 0.109 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.785973e-01 0.109 0 0
MyD88-independent TLR4 cascade R-HSA-166166 7.785973e-01 0.109 0 0
Hedgehog 'off' state R-HSA-5610787 7.804861e-01 0.108 0 0
Gastrulation R-HSA-9758941 7.834540e-01 0.106 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 7.870292e-01 0.104 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 7.870292e-01 0.104 0 0
Mitochondrial mRNA modification R-HSA-9937008 7.870292e-01 0.104 0 0
Syndecan interactions R-HSA-3000170 7.870292e-01 0.104 0 0
Growth hormone receptor signaling R-HSA-982772 7.870292e-01 0.104 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 7.871496e-01 0.104 0 0
Regulation of TNFR1 signaling R-HSA-5357905 7.890481e-01 0.103 0 0
RAF/MAP kinase cascade R-HSA-5673001 7.895928e-01 0.103 0 0
Regulation of Apoptosis R-HSA-169911 7.917577e-01 0.101 0 0
Signalling to ERKs R-HSA-187687 7.917577e-01 0.101 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 7.917577e-01 0.101 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 7.926539e-01 0.101 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 7.926539e-01 0.101 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 7.926539e-01 0.101 0 0
Chromosome Maintenance R-HSA-73886 7.928712e-01 0.101 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.946770e-01 0.100 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.946770e-01 0.100 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 7.992044e-01 0.097 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 7.992044e-01 0.097 0 0
Maple Syrup Urine Disease R-HSA-9865114 7.992044e-01 0.097 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 7.992044e-01 0.097 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 7.992044e-01 0.097 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 7.992044e-01 0.097 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 7.992044e-01 0.097 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 7.992044e-01 0.097 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 7.992044e-01 0.097 0 0
p75NTR recruits signalling complexes R-HSA-209543 7.992044e-01 0.097 0 0
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854 7.992044e-01 0.097 0 0
Signaling by LTK R-HSA-9842663 7.992044e-01 0.097 0 0
VLDLR internalisation and degradation R-HSA-8866427 7.992044e-01 0.097 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 7.992044e-01 0.097 0 0
Regulation of IFNG signaling R-HSA-877312 7.992044e-01 0.097 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 7.992044e-01 0.097 0 0
MET activates RAS signaling R-HSA-8851805 7.992044e-01 0.097 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 7.992044e-01 0.097 0 0
OAS antiviral response R-HSA-8983711 7.992044e-01 0.097 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 7.992044e-01 0.097 0 0
Interleukin-15 signaling R-HSA-8983432 7.992044e-01 0.097 0 0
Extension of Telomeres R-HSA-180786 8.004352e-01 0.097 0 0
Amino acid transport across the plasma membrane R-HSA-352230 8.004352e-01 0.097 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 8.005974e-01 0.097 0 0
Protein folding R-HSA-391251 8.006286e-01 0.097 1 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 8.022909e-01 0.096 0 0
Regulation of mitotic cell cycle R-HSA-453276 8.022909e-01 0.096 0 0
Hedgehog 'on' state R-HSA-5632684 8.022909e-01 0.096 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 8.024338e-01 0.096 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 8.024338e-01 0.096 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 8.045995e-01 0.094 0 0
RUNX2 regulates bone development R-HSA-8941326 8.045995e-01 0.094 0 0
MHC class II antigen presentation R-HSA-2132295 8.075770e-01 0.093 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.084527e-01 0.092 0 0
Degradation of AXIN R-HSA-4641257 8.167680e-01 0.088 0 0
Defects in cobalamin (B12) metabolism R-HSA-3296469 8.168399e-01 0.088 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 8.168399e-01 0.088 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 8.183843e-01 0.087 0 0
Adenylate cyclase activating pathway R-HSA-170660 8.183843e-01 0.087 0 0
Chylomicron remodeling R-HSA-8963901 8.183843e-01 0.087 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 8.183843e-01 0.087 0 0
Formation of axial mesoderm R-HSA-9796292 8.183843e-01 0.087 0 0
Frs2-mediated activation R-HSA-170968 8.183843e-01 0.087 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 8.183843e-01 0.087 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 8.183843e-01 0.087 0 0
rRNA modification in the mitochondrion R-HSA-6793080 8.183843e-01 0.087 0 0
Maturation of nucleoprotein R-HSA-9683610 8.183843e-01 0.087 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 8.183843e-01 0.087 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 8.183843e-01 0.087 0 0
MAP kinase activation R-HSA-450294 8.201889e-01 0.086 0 0
Ca2+ pathway R-HSA-4086398 8.205172e-01 0.086 0 0
Gap junction trafficking and regulation R-HSA-157858 8.221566e-01 0.085 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 8.234416e-01 0.084 0 0
Signaling by ERBB4 R-HSA-1236394 8.291183e-01 0.081 0 0
NCAM signaling for neurite out-growth R-HSA-375165 8.294587e-01 0.081 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 8.294587e-01 0.081 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 8.302177e-01 0.081 0 0
MET activates PTK2 signaling R-HSA-8874081 8.302978e-01 0.081 0 0
Sphingolipid catabolism R-HSA-9845614 8.302978e-01 0.081 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 8.302978e-01 0.081 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 8.302978e-01 0.081 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 8.302978e-01 0.081 0 0
PI3K Cascade R-HSA-109704 8.321929e-01 0.080 0 0
Organelle biogenesis and maintenance R-HSA-1852241 8.335931e-01 0.079 0 0
SARS-CoV-1-host interactions R-HSA-9692914 8.347970e-01 0.078 0 0
Removal of the Flap Intermediate R-HSA-69166 8.357332e-01 0.078 0 0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV R-HSA-9859138 8.357332e-01 0.078 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 8.357332e-01 0.078 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 8.357332e-01 0.078 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 8.357332e-01 0.078 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 8.357332e-01 0.078 0 0
Regulation of KIT signaling R-HSA-1433559 8.357332e-01 0.078 0 0
Hydrolysis of LPC R-HSA-1483115 8.357332e-01 0.078 0 0
Signaling by FGFR4 in disease R-HSA-5655291 8.357332e-01 0.078 0 0
CRMPs in Sema3A signaling R-HSA-399956 8.357332e-01 0.078 0 0
Non-canonical inflammasome activation R-HSA-9686114 8.357332e-01 0.078 0 0
Acyl chain remodeling of CL R-HSA-1482798 8.357332e-01 0.078 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 8.357332e-01 0.078 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 8.373867e-01 0.077 0 0
Stabilization of p53 R-HSA-69541 8.391780e-01 0.076 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 8.391780e-01 0.076 1 0
Meiotic recombination R-HSA-912446 8.417525e-01 0.075 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 8.428570e-01 0.074 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 8.428570e-01 0.074 0 0
Insulin receptor signalling cascade R-HSA-74751 8.468302e-01 0.072 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 8.468302e-01 0.072 0 0
Ion transport by P-type ATPases R-HSA-936837 8.468302e-01 0.072 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 8.470378e-01 0.072 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 8.494673e-01 0.071 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 8.494673e-01 0.071 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 8.494673e-01 0.071 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 8.494673e-01 0.071 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.508498e-01 0.070 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 8.508498e-01 0.070 0 0
Erythropoietin activates RAS R-HSA-9027284 8.514258e-01 0.070 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 8.514258e-01 0.070 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 8.514258e-01 0.070 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 8.514258e-01 0.070 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 8.514258e-01 0.070 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 8.514258e-01 0.070 0 0
G beta:gamma signalling through BTK R-HSA-8964315 8.514258e-01 0.070 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 8.514258e-01 0.070 0 0
Telomere C-strand synthesis initiation R-HSA-174430 8.514258e-01 0.070 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 8.514258e-01 0.070 0 0
Transport and metabolism of PAPS R-HSA-174362 8.514258e-01 0.070 0 0
p38MAPK events R-HSA-171007 8.514258e-01 0.070 0 0
Biotin transport and metabolism R-HSA-196780 8.514258e-01 0.070 0 0
Protein lipoylation R-HSA-9857492 8.514258e-01 0.070 0 0
Other semaphorin interactions R-HSA-416700 8.514258e-01 0.070 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 8.514258e-01 0.070 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 8.514258e-01 0.070 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 8.514258e-01 0.070 0 0
Protein methylation R-HSA-8876725 8.514258e-01 0.070 0 0
Post-translational protein phosphorylation R-HSA-8957275 8.532332e-01 0.069 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 8.532332e-01 0.069 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 8.532332e-01 0.069 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 8.532332e-01 0.069 0 0
Telomere Extension By Telomerase R-HSA-171319 8.545665e-01 0.068 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 8.545665e-01 0.068 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.545665e-01 0.068 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 8.545665e-01 0.068 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 8.545665e-01 0.068 0 0
Inflammasomes R-HSA-622312 8.545665e-01 0.068 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 8.564868e-01 0.067 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 8.564868e-01 0.067 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 8.591783e-01 0.066 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 8.591783e-01 0.066 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 8.591783e-01 0.066 0 0
SARS-CoV-2-host interactions R-HSA-9705683 8.629902e-01 0.064 0 0
Signaling by Erythropoietin R-HSA-9006335 8.654739e-01 0.063 0 0
Termination of translesion DNA synthesis R-HSA-5656169 8.654739e-01 0.063 0 0
Regulation of gene expression in beta cells R-HSA-210745 8.654739e-01 0.063 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 8.654739e-01 0.063 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 8.656201e-01 0.063 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 8.656201e-01 0.063 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 8.656201e-01 0.063 0 0
Activation of SMO R-HSA-5635838 8.656201e-01 0.063 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 8.656201e-01 0.063 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 8.656201e-01 0.063 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 8.656201e-01 0.063 0 0
ABC-family proteins mediated transport R-HSA-382556 8.660323e-01 0.062 0 0
Glycolysis R-HSA-70171 8.660323e-01 0.062 0 0
Neurotransmitter release cycle R-HSA-112310 8.660957e-01 0.062 0 0
Generic Transcription Pathway R-HSA-212436 8.674188e-01 0.062 1 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 8.677180e-01 0.062 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 8.683354e-01 0.061 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 8.683354e-01 0.061 0 0
Scavenging by Class A Receptors R-HSA-3000480 8.683354e-01 0.061 0 0
Negative regulation of MAPK pathway R-HSA-5675221 8.683354e-01 0.061 0 0
Interleukin-1 family signaling R-HSA-446652 8.687834e-01 0.061 0 0
SLC-mediated transport of amino acids R-HSA-9958863 8.701189e-01 0.060 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 8.724694e-01 0.059 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 8.734695e-01 0.059 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 8.734695e-01 0.059 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 8.739929e-01 0.058 0 0
Signaling by MET R-HSA-6806834 8.739929e-01 0.058 0 0
Signaling by FGFR2 R-HSA-5654738 8.739929e-01 0.058 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 8.756255e-01 0.058 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.756255e-01 0.058 0 0
Activation of BH3-only proteins R-HSA-114452 8.756255e-01 0.058 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 8.784590e-01 0.056 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 8.784590e-01 0.056 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 8.784590e-01 0.056 0 0
Scavenging by Class B Receptors R-HSA-3000471 8.784590e-01 0.056 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 8.784590e-01 0.056 0 0
Fibronectin matrix formation R-HSA-1566977 8.784590e-01 0.056 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 8.784590e-01 0.056 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 8.784590e-01 0.056 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 8.784590e-01 0.056 0 0
Synthesis of PG R-HSA-1483148 8.784590e-01 0.056 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 8.784590e-01 0.056 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 8.784590e-01 0.056 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 8.785901e-01 0.056 0 0
Signaling by Insulin receptor R-HSA-74752 8.844645e-01 0.053 0 0
Eukaryotic Translation Elongation R-HSA-156842 8.844645e-01 0.053 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 8.850662e-01 0.053 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 8.850662e-01 0.053 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 8.850844e-01 0.053 0 0
Signaling by SCF-KIT R-HSA-1433557 8.850844e-01 0.053 0 0
Signaling by FGFR4 R-HSA-5654743 8.850844e-01 0.053 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 8.865716e-01 0.052 0 0
IRS-mediated signalling R-HSA-112399 8.899334e-01 0.051 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 8.900720e-01 0.051 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 8.900720e-01 0.051 0 0
Glycogen storage diseases R-HSA-3229121 8.900720e-01 0.051 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 8.900720e-01 0.051 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 8.900720e-01 0.051 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.900720e-01 0.051 0 0
Interleukin-17 signaling R-HSA-448424 8.903402e-01 0.050 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 8.910472e-01 0.050 0 0
DAP12 interactions R-HSA-2172127 8.927239e-01 0.049 0 0
G1 Phase R-HSA-69236 8.927239e-01 0.049 0 0
Cyclin D associated events in G1 R-HSA-69231 8.927239e-01 0.049 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 8.927239e-01 0.049 0 0
Signaling by WNT in cancer R-HSA-4791275 8.938391e-01 0.049 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 8.938391e-01 0.049 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.938391e-01 0.049 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 8.999044e-01 0.046 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 8.999044e-01 0.046 0 0
Somitogenesis R-HSA-9824272 8.999044e-01 0.046 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 8.999044e-01 0.046 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.999044e-01 0.046 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 8.999044e-01 0.046 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 8.999044e-01 0.046 0 0
Signaling by FGFR3 R-HSA-5654741 8.999044e-01 0.046 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 9.005760e-01 0.045 0 0
Synaptic adhesion-like molecules R-HSA-8849932 9.005760e-01 0.045 0 0
Presynaptic function of Kainate receptors R-HSA-500657 9.005760e-01 0.045 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 9.005760e-01 0.045 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.006761e-01 0.045 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 9.006761e-01 0.045 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 9.019855e-01 0.045 0 0
Regulation of necroptotic cell death R-HSA-5675482 9.019855e-01 0.045 0 0
Interferon Signaling R-HSA-913531 9.022178e-01 0.045 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 9.022627e-01 0.045 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 9.032092e-01 0.044 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.056317e-01 0.043 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 9.066485e-01 0.043 0 0
Ribosome-associated quality control R-HSA-9948299 9.067980e-01 0.042 0 0
Signaling by Hedgehog R-HSA-5358351 9.067980e-01 0.042 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.085545e-01 0.042 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.095451e-01 0.041 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 9.095451e-01 0.041 1 1
Vpu mediated degradation of CD4 R-HSA-180534 9.095451e-01 0.041 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 9.095451e-01 0.041 0 0
Translesion Synthesis by POLH R-HSA-110320 9.100769e-01 0.041 0 0
Germ layer formation at gastrulation R-HSA-9754189 9.100769e-01 0.041 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.100769e-01 0.041 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.100769e-01 0.041 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.100769e-01 0.041 0 0
Maturation of nucleoprotein R-HSA-9694631 9.100769e-01 0.041 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 9.100769e-01 0.041 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 9.100769e-01 0.041 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 9.128229e-01 0.040 0 0
Synthesis of PC R-HSA-1483191 9.129783e-01 0.040 1 1
Signaling by NOTCH4 R-HSA-9013694 9.130406e-01 0.040 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 9.148624e-01 0.039 0 0
Telomere Maintenance R-HSA-157579 9.149109e-01 0.039 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.156314e-01 0.038 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 9.156404e-01 0.038 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 9.165556e-01 0.038 0 0
eNOS activation R-HSA-203615 9.165556e-01 0.038 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 9.165556e-01 0.038 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.165556e-01 0.038 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.165556e-01 0.038 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.165556e-01 0.038 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.165556e-01 0.038 0 0
Signal amplification R-HSA-392518 9.165556e-01 0.038 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.165556e-01 0.038 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 9.170392e-01 0.038 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.181964e-01 0.037 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.182406e-01 0.037 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.186704e-01 0.037 0 0
Glycogen synthesis R-HSA-3322077 9.186704e-01 0.037 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 9.186704e-01 0.037 0 0
Negative regulation of MET activity R-HSA-6807004 9.186704e-01 0.037 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.186704e-01 0.037 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 9.186704e-01 0.037 0 0
Pregnenolone biosynthesis R-HSA-196108 9.186704e-01 0.037 0 0
Protein hydroxylation R-HSA-9629569 9.186704e-01 0.037 0 0
Intraflagellar transport R-HSA-5620924 9.189153e-01 0.037 0 0
Co-stimulation by CD28 R-HSA-389356 9.189153e-01 0.037 0 0
Peptide chain elongation R-HSA-156902 9.225278e-01 0.035 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.230529e-01 0.035 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.230529e-01 0.035 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.230529e-01 0.035 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.230529e-01 0.035 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 9.244800e-01 0.034 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 9.244800e-01 0.034 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.244800e-01 0.034 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.247567e-01 0.034 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 9.264431e-01 0.033 0 0
Signalling to RAS R-HSA-167044 9.264431e-01 0.033 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 9.264431e-01 0.033 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 9.264431e-01 0.033 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 9.264431e-01 0.033 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.264431e-01 0.033 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 9.271066e-01 0.033 0 0
SLC transporter disorders R-HSA-5619102 9.280504e-01 0.032 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.290710e-01 0.032 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.290710e-01 0.032 0 0
G1/S-Specific Transcription R-HSA-69205 9.290710e-01 0.032 0 0
Regulation of RAS by GAPs R-HSA-5658442 9.296927e-01 0.032 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.296927e-01 0.032 0 0
Interleukin-1 signaling R-HSA-9020702 9.311279e-01 0.031 0 0
Toll-like Receptor Cascades R-HSA-168898 9.314127e-01 0.031 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 9.321967e-01 0.030 0 0
CS-GAG biosynthesis R-HSA-2022870 9.334734e-01 0.030 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 9.334734e-01 0.030 0 0
Attachment and Entry R-HSA-9694614 9.334734e-01 0.030 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.334734e-01 0.030 0 0
Assembly Of The HIV Virion R-HSA-175474 9.334734e-01 0.030 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.345725e-01 0.029 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.345725e-01 0.029 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.346421e-01 0.029 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.346421e-01 0.029 0 0
Metabolism of folate and pterines R-HSA-196757 9.346421e-01 0.029 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 9.347326e-01 0.029 0 0
Signaling by NOTCH R-HSA-157118 9.386354e-01 0.028 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.388267e-01 0.027 0 0
tRNA processing R-HSA-72306 9.393433e-01 0.027 0 0
PKR-mediated signaling R-HSA-9833482 9.393527e-01 0.027 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.397966e-01 0.027 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 9.397966e-01 0.027 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 9.398321e-01 0.027 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 9.398321e-01 0.027 0 0
Signaling by KIT in disease R-HSA-9669938 9.398321e-01 0.027 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 9.398321e-01 0.027 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 9.398321e-01 0.027 0 0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy R-HSA-9857377 9.398321e-01 0.027 0 0
Cellular hexose transport R-HSA-189200 9.398321e-01 0.027 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 9.419231e-01 0.026 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 9.443941e-01 0.025 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.445634e-01 0.025 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.445634e-01 0.025 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 9.455834e-01 0.024 0 0
Interleukin receptor SHC signaling R-HSA-912526 9.455834e-01 0.024 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.455834e-01 0.024 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 9.455834e-01 0.024 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 9.455834e-01 0.024 0 0
Carnitine shuttle R-HSA-200425 9.455834e-01 0.024 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 9.480748e-01 0.023 0 0
Glycogen metabolism R-HSA-8982491 9.489693e-01 0.023 0 0
rRNA processing in the mitochondrion R-HSA-8868766 9.489693e-01 0.023 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.489693e-01 0.023 0 0
Tryptophan catabolism R-HSA-71240 9.489693e-01 0.023 0 0
Mitochondrial biogenesis R-HSA-1592230 9.503987e-01 0.022 0 0
Glucose metabolism R-HSA-70326 9.503987e-01 0.022 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.507853e-01 0.022 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.507853e-01 0.022 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 9.507853e-01 0.022 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 9.507853e-01 0.022 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.507853e-01 0.022 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.507853e-01 0.022 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.507853e-01 0.022 0 0
Neurodegenerative Diseases R-HSA-8863678 9.507853e-01 0.022 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 9.507853e-01 0.022 0 0
Parasite infection R-HSA-9664407 9.517567e-01 0.021 0 0
Leishmania phagocytosis R-HSA-9664417 9.517567e-01 0.021 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.517567e-01 0.021 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.528436e-01 0.021 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.530399e-01 0.021 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.530399e-01 0.021 0 0
FLT3 Signaling R-HSA-9607240 9.530399e-01 0.021 0 0
Maturation of spike protein R-HSA-9694548 9.530399e-01 0.021 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.530399e-01 0.021 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.530643e-01 0.021 0 0
Eukaryotic Translation Termination R-HSA-72764 9.538317e-01 0.021 0 0
Signaling by FGFR1 R-HSA-5654736 9.546023e-01 0.020 0 0
Tight junction interactions R-HSA-420029 9.554901e-01 0.020 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.554901e-01 0.020 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.554901e-01 0.020 0 0
Laminin interactions R-HSA-3000157 9.554901e-01 0.020 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.556251e-01 0.020 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.567988e-01 0.019 0 0
Intra-Golgi traffic R-HSA-6811438 9.567988e-01 0.019 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.567988e-01 0.019 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.567988e-01 0.019 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 9.597455e-01 0.018 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 9.597455e-01 0.018 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.597455e-01 0.018 0 0
TRP channels R-HSA-3295583 9.597455e-01 0.018 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.602686e-01 0.018 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.602686e-01 0.018 0 0
Depyrimidination R-HSA-73928 9.602686e-01 0.018 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 9.602686e-01 0.018 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.608759e-01 0.017 0 0
Signaling by FGFR R-HSA-190236 9.613897e-01 0.017 0 0
Packaging Of Telomere Ends R-HSA-171306 9.635942e-01 0.016 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.635942e-01 0.016 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.635942e-01 0.016 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.635942e-01 0.016 0 0
Triglyceride biosynthesis R-HSA-75109 9.635942e-01 0.016 0 0
Synthesis of PE R-HSA-1483213 9.635942e-01 0.016 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 9.635942e-01 0.016 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.635942e-01 0.016 1 1
Peroxisomal protein import R-HSA-9033241 9.636981e-01 0.016 0 0
Regulation of beta-cell development R-HSA-186712 9.636981e-01 0.016 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.641197e-01 0.016 0 0
Translation R-HSA-72766 9.651265e-01 0.015 0 0
tRNA Aminoacylation R-HSA-379724 9.663278e-01 0.015 0 0
Iron uptake and transport R-HSA-917937 9.663345e-01 0.015 0 0
Proteasome assembly R-HSA-9907900 9.664228e-01 0.015 0 0
Gap junction trafficking R-HSA-190828 9.664228e-01 0.015 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.664228e-01 0.015 0 0
Amine ligand-binding receptors R-HSA-375280 9.664228e-01 0.015 0 0
HCMV Early Events R-HSA-9609690 9.670169e-01 0.015 0 0
Iron assimilation using enterobactin R-HSA-9638334 9.670752e-01 0.015 0 0
Pyrimidine salvage R-HSA-73614 9.670752e-01 0.015 0 0
ER-Phagosome pathway R-HSA-1236974 9.677044e-01 0.014 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 9.678037e-01 0.014 0 0
Selenocysteine synthesis R-HSA-2408557 9.678037e-01 0.014 0 0
Parasitic Infection Pathways R-HSA-9824443 9.683527e-01 0.014 0 0
Leishmania infection R-HSA-9658195 9.683527e-01 0.014 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.687770e-01 0.014 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.687770e-01 0.014 0 0
Aquaporin-mediated transport R-HSA-445717 9.687770e-01 0.014 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.691451e-01 0.014 0 0
Downstream TCR signaling R-HSA-202424 9.697325e-01 0.013 0 0
Late endosomal microautophagy R-HSA-9615710 9.702235e-01 0.013 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 9.702235e-01 0.013 0 0
DNA methylation R-HSA-5334118 9.702235e-01 0.013 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 9.702235e-01 0.013 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 9.702235e-01 0.013 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 9.702235e-01 0.013 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.702235e-01 0.013 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.715203e-01 0.013 0 0
Viral mRNA Translation R-HSA-192823 9.715203e-01 0.013 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.716540e-01 0.012 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.716540e-01 0.012 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.716540e-01 0.012 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.716540e-01 0.012 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.726814e-01 0.012 0 0
Integrin cell surface interactions R-HSA-216083 9.726814e-01 0.012 0 0
ABC transporter disorders R-HSA-5619084 9.726814e-01 0.012 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 9.730709e-01 0.012 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 9.730709e-01 0.012 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 9.731787e-01 0.012 0 0
Signaling by PTK6 R-HSA-8848021 9.731787e-01 0.012 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 9.731787e-01 0.012 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.745349e-01 0.011 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.751304e-01 0.011 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 9.756462e-01 0.011 0 0
Budding and maturation of HIV virion R-HSA-162588 9.756462e-01 0.011 0 0
Cargo concentration in the ER R-HSA-5694530 9.756462e-01 0.011 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 9.756462e-01 0.011 0 0
EGFR downregulation R-HSA-182971 9.756462e-01 0.011 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.760942e-01 0.011 0 0
NGF-stimulated transcription R-HSA-9031628 9.760942e-01 0.011 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.767207e-01 0.010 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.767710e-01 0.010 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 9.779181e-01 0.010 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 9.779754e-01 0.010 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.786929e-01 0.009 0 0
Adipogenesis R-HSA-9843745 9.795599e-01 0.009 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.798579e-01 0.009 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 9.800819e-01 0.009 0 0
Cardiogenesis R-HSA-9733709 9.800819e-01 0.009 0 0
Circadian clock R-HSA-9909396 9.807069e-01 0.008 1 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.808312e-01 0.008 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.808312e-01 0.008 0 0
HCMV Late Events R-HSA-9610379 9.809141e-01 0.008 0 0
The phototransduction cascade R-HSA-2514856 9.815175e-01 0.008 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.815175e-01 0.008 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.819160e-01 0.008 0 0
Striated Muscle Contraction R-HSA-390522 9.819871e-01 0.008 0 0
CS/DS degradation R-HSA-2024101 9.819871e-01 0.008 0 0
Effects of PIP2 hydrolysis R-HSA-114508 9.819871e-01 0.008 0 0
Heme degradation R-HSA-189483 9.819871e-01 0.008 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.821795e-01 0.008 0 0
Neddylation R-HSA-8951664 9.823144e-01 0.008 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.826867e-01 0.008 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.830217e-01 0.007 0 0
SARS-CoV Infections R-HSA-9679506 9.830789e-01 0.007 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.837101e-01 0.007 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.837101e-01 0.007 1 1
RA biosynthesis pathway R-HSA-5365859 9.837101e-01 0.007 0 0
Signaling by Interleukins R-HSA-449147 9.837487e-01 0.007 0 0
Regulation of insulin secretion R-HSA-422356 9.844343e-01 0.007 0 0
Transmission across Chemical Synapses R-HSA-112315 9.845303e-01 0.007 0 0
Co-inhibition by PD-1 R-HSA-389948 9.851242e-01 0.007 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.852684e-01 0.006 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.852684e-01 0.006 0 0
Oncogene Induced Senescence R-HSA-2559585 9.852684e-01 0.006 0 0
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775 9.852684e-01 0.006 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 9.855607e-01 0.006 0 0
Retinoid metabolism and transport R-HSA-975634 9.855607e-01 0.006 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.855951e-01 0.006 0 0
Integration of energy metabolism R-HSA-163685 9.856009e-01 0.006 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.857384e-01 0.006 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 9.857894e-01 0.006 0 0
SARS-CoV-1 Infection R-HSA-9678108 9.859924e-01 0.006 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.864294e-01 0.006 1 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 9.866520e-01 0.006 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 9.866777e-01 0.006 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.866777e-01 0.006 0 0
GPVI-mediated activation cascade R-HSA-114604 9.866777e-01 0.006 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.872172e-01 0.006 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.872359e-01 0.006 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.879523e-01 0.005 0 0
Cleavage of the damaged purine R-HSA-110331 9.879523e-01 0.005 0 0
Cellular response to chemical stress R-HSA-9711123 9.884491e-01 0.005 1 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.890517e-01 0.005 0 0
tRNA processing in the mitochondrion R-HSA-6785470 9.891050e-01 0.005 0 0
Depurination R-HSA-73927 9.891050e-01 0.005 0 0
Phospholipid metabolism R-HSA-1483257 9.894208e-01 0.005 1 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.899343e-01 0.004 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 9.900438e-01 0.004 0 0
RAS processing R-HSA-9648002 9.901475e-01 0.004 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.901475e-01 0.004 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 9.903848e-01 0.004 0 0
Activation of HOX genes during differentiation R-HSA-5619507 9.903848e-01 0.004 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.910212e-01 0.004 0 0
Translation of Structural Proteins R-HSA-9694635 9.910212e-01 0.004 0 0
Interleukin-2 family signaling R-HSA-451927 9.910903e-01 0.004 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.910903e-01 0.004 0 0
Cardiac conduction R-HSA-5576891 9.912471e-01 0.004 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.914164e-01 0.004 0 0
Metabolism of polyamines R-HSA-351202 9.915529e-01 0.004 0 0
Platelet homeostasis R-HSA-418346 9.916398e-01 0.004 0 0
Developmental Cell Lineages R-HSA-9734767 9.919510e-01 0.004 0 0
Interferon gamma signaling R-HSA-877300 9.920899e-01 0.003 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.922958e-01 0.003 0 0
Muscle contraction R-HSA-397014 9.923893e-01 0.003 0 0
Translation of Structural Proteins R-HSA-9683701 9.927140e-01 0.003 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.927379e-01 0.003 0 0
Stimuli-sensing channels R-HSA-2672351 9.927379e-01 0.003 0 0
Activation of GABAB receptors R-HSA-991365 9.934113e-01 0.003 0 0
GABA B receptor activation R-HSA-977444 9.934113e-01 0.003 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 9.934113e-01 0.003 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.934113e-01 0.003 0 0
Cytokine Signaling in Immune system R-HSA-1280215 9.934315e-01 0.003 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.934879e-01 0.003 0 0
Amyloid fiber formation R-HSA-977225 9.934879e-01 0.003 0 0
Ion channel transport R-HSA-983712 9.935060e-01 0.003 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.939814e-01 0.003 0 0
Mitochondrial translation elongation R-HSA-5389840 9.940998e-01 0.003 0 0
Cellular response to hypoxia R-HSA-1234174 9.945663e-01 0.002 0 0
Surfactant metabolism R-HSA-5683826 9.946122e-01 0.002 0 0
Methylation R-HSA-156581 9.946122e-01 0.002 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.946122e-01 0.002 0 0
Mitochondrial translation initiation R-HSA-5368286 9.949291e-01 0.002 0 0
FOXO-mediated transcription R-HSA-9614085 9.953005e-01 0.002 0 0
Platelet degranulation R-HSA-114608 9.954302e-01 0.002 0 0
PPARA activates gene expression R-HSA-1989781 9.957849e-01 0.002 0 0
HCMV Infection R-HSA-9609646 9.958303e-01 0.002 0 0
Regulated Necrosis R-HSA-5218859 9.958378e-01 0.002 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.962896e-01 0.002 0 0
G alpha (s) signalling events R-HSA-418555 9.964029e-01 0.002 0 0
COPII-mediated vesicle transport R-HSA-204005 9.965179e-01 0.002 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.967424e-01 0.001 0 0
ECM proteoglycans R-HSA-3000178 9.968158e-01 0.001 0 0
Metabolism of cofactors R-HSA-8978934 9.968158e-01 0.001 0 0
Azathioprine ADME R-HSA-9748787 9.970544e-01 0.001 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.973364e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.975669e-01 0.001 0 0
Selenoamino acid metabolism R-HSA-2408522 9.976398e-01 0.001 0 0
Mitochondrial translation termination R-HSA-5419276 9.979903e-01 0.001 0 0
Mitochondrial translation R-HSA-5368287 9.981590e-01 0.001 0 0
Protein localization R-HSA-9609507 9.982095e-01 0.001 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.982194e-01 0.001 0 0
G alpha (z) signalling events R-HSA-418597 9.982194e-01 0.001 0 0
Paracetamol ADME R-HSA-9753281 9.982194e-01 0.001 0 0
Interleukin-10 signaling R-HSA-6783783 9.983033e-01 0.001 0 0
Synthesis of PA R-HSA-1483166 9.985441e-01 0.001 0 0
Sphingolipid metabolism R-HSA-428157 9.986319e-01 0.001 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.987823e-01 0.001 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.987823e-01 0.001 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.987937e-01 0.001 1 0
Triglyceride metabolism R-HSA-8979227 9.988097e-01 0.001 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.988097e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.988513e-01 0.000 0 0
GABA receptor activation R-HSA-977443 9.989238e-01 0.000 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.989238e-01 0.000 0 0
Collagen degradation R-HSA-1442490 9.990269e-01 0.000 0 0
Nucleotide salvage R-HSA-8956321 9.990269e-01 0.000 0 0
Developmental Biology R-HSA-1266738 9.990832e-01 0.000 1 0
Peptide hormone metabolism R-HSA-2980736 9.990886e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.992044e-01 0.000 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.992509e-01 0.000 0 0
Post-translational protein modification R-HSA-597592 9.993018e-01 0.000 0 0
RSV-host interactions R-HSA-9833110 9.993090e-01 0.000 0 0
Pyruvate metabolism R-HSA-70268 9.993163e-01 0.000 0 0
Neuronal System R-HSA-112316 9.993183e-01 0.000 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.994683e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.994683e-01 0.000 0 0
Metabolism of steroid hormones R-HSA-196071 9.994683e-01 0.000 0 0
Formation of the cornified envelope R-HSA-6809371 9.994808e-01 0.000 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.994966e-01 0.000 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 9.995585e-01 0.000 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 9.995585e-01 0.000 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 9.995585e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.995863e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.996070e-01 0.000 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.996447e-01 0.000 0 0
Metal ion assimilation from the host R-HSA-9638482 9.996447e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.996447e-01 0.000 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.996788e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.996844e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.997096e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.997504e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.997512e-01 0.000 0 0
Interferon alpha/beta signaling R-HSA-909733 9.997738e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.998029e-01 0.000 0 0
Cholesterol biosynthesis R-HSA-191273 9.998246e-01 0.000 0 0
Neutrophil degranulation R-HSA-6798695 9.998286e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.998414e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999042e-01 0.000 0 0
Viral Infection Pathways R-HSA-9824446 9.999043e-01 0.000 1 0
Diseases of programmed cell death R-HSA-9645723 9.999422e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.999488e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.999527e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.999572e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999634e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.999679e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.999684e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.999715e-01 0.000 0 0
Collagen formation R-HSA-1474290 9.999715e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999728e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.999742e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999780e-01 0.000 0 0
Adaptive Immune System R-HSA-1280218 9.999787e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999861e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999901e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999915e-01 0.000 0 0
Hemostasis R-HSA-109582 9.999932e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999949e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999958e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999970e-01 0.000 0 0
Regulation of Complement cascade R-HSA-977606 9.999992e-01 0.000 0 0
G alpha (q) signalling events R-HSA-416476 9.999997e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999997e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999997e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999998e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.999998e-01 0.000 1 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999999e-01 0.000 0 0
Complement cascade R-HSA-166658 9.999999e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999999e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
GPCR downstream signalling R-HSA-388396 1.000000e+00 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Infectious disease R-HSA-5663205 1.000000e+00 0.000 1 0
Respiratory electron transport R-HSA-611105 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Immune System R-HSA-168256 1.000000e+00 0.000 0 0
Innate Immune System R-HSA-168249 1.000000e+00 0.000 0 0
Metabolism of nucleotides R-HSA-15869 1.000000e+00 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.000000e+00 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
Disease R-HSA-1643685 1.000000e+00 0.000 1 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 1 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 1 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 1.000000e+00 0.000 1 1
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Attenuation phase R-HSA-3371568 7.807088e-13 12.108 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 3.915868e-12 11.407 0 0
Cellular response to heat stress R-HSA-3371556 1.607292e-11 10.794 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 3.348644e-11 10.475 0 0
HSF1-dependent transactivation R-HSA-3371571 7.805856e-11 10.108 0 0
Metabolism of RNA R-HSA-8953854 7.802692e-11 10.108 0 0
HSF1 activation R-HSA-3371511 3.035886e-10 9.518 0 0
mRNA Splicing - Major Pathway R-HSA-72163 6.796897e-10 9.168 0 0
mRNA Splicing R-HSA-72172 1.092775e-09 8.961 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 4.659698e-06 5.332 0 0
Repression of WNT target genes R-HSA-4641265 5.149294e-06 5.288 0 0
Cell Cycle R-HSA-1640170 6.360408e-06 5.197 1 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.172378e-05 4.663 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.640558e-05 4.578 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.717457e-05 4.566 0 0
Gene expression (Transcription) R-HSA-74160 3.208729e-05 4.494 1 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 4.445842e-05 4.352 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 4.527063e-05 4.344 0 0
DNA Repair R-HSA-73894 5.032352e-05 4.298 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 8.800791e-05 4.055 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.100639e-04 3.958 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.765113e-04 3.753 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 2.269812e-04 3.644 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 2.482233e-04 3.605 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 2.513800e-04 3.600 0 0
Chromatin organization R-HSA-4839726 2.716384e-04 3.566 0 0
Chromatin modifying enzymes R-HSA-3247509 3.655892e-04 3.437 0 0
Estrogen-dependent gene expression R-HSA-9018519 3.931018e-04 3.405 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 4.641060e-04 3.333 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 5.308896e-04 3.275 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.447405e-04 3.264 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 6.201713e-04 3.207 0 0
MITF-M-dependent gene expression R-HSA-9856651 6.693526e-04 3.174 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 6.949867e-04 3.158 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.031217e-03 2.987 1 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.031217e-03 2.987 1 0
Cell-cell junction organization R-HSA-421270 1.130050e-03 2.947 1 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.325170e-03 2.878 0 0
Homology Directed Repair R-HSA-5693538 1.513918e-03 2.820 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.656904e-03 2.781 1 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 1.969049e-03 2.706 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 1.846908e-03 2.734 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.970943e-03 2.705 0 0
RNA Polymerase III Transcription R-HSA-74158 1.969049e-03 2.706 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.982954e-03 2.703 0 0
Cell Cycle, Mitotic R-HSA-69278 1.900333e-03 2.721 1 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.114858e-03 2.675 0 0
HIV Life Cycle R-HSA-162587 2.423623e-03 2.616 0 0
mRNA 3'-end processing R-HSA-72187 2.551402e-03 2.593 0 0
Regulation of PTEN gene transcription R-HSA-8943724 2.538011e-03 2.596 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.623711e-03 2.581 1 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 3.694874e-03 2.432 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 3.694874e-03 2.432 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 3.694874e-03 2.432 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 3.694874e-03 2.432 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 3.694874e-03 2.432 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 3.694874e-03 2.432 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 3.694874e-03 2.432 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 3.694874e-03 2.432 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 3.694874e-03 2.432 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 3.694874e-03 2.432 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 3.694874e-03 2.432 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.167848e-03 2.499 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.676371e-03 2.435 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.289948e-03 2.483 0 0
Adherens junctions interactions R-HSA-418990 3.181839e-03 2.497 1 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.958748e-03 2.529 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 3.467997e-03 2.460 0 0
Regulation of TP53 Activity R-HSA-5633007 3.006764e-03 2.522 1 0
RNA Polymerase II Transcription R-HSA-73857 3.767661e-03 2.424 1 0
Cellular responses to stress R-HSA-2262752 3.770420e-03 2.424 1 0
Processing of DNA double-strand break ends R-HSA-5693607 4.005081e-03 2.397 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 4.304461e-03 2.366 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.231890e-03 2.373 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 4.892891e-03 2.310 0 0
Cell junction organization R-HSA-446728 5.130665e-03 2.290 1 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 5.239180e-03 2.281 0 0
Signaling by ALK in cancer R-HSA-9700206 5.239180e-03 2.281 0 0
Cell Cycle Checkpoints R-HSA-69620 5.358116e-03 2.271 0 0
snRNP Assembly R-HSA-191859 5.998561e-03 2.222 0 0
Metabolism of non-coding RNA R-HSA-194441 5.998561e-03 2.222 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.128584e-03 2.213 0 0
Cellular responses to stimuli R-HSA-8953897 6.556848e-03 2.183 1 0
RUNX3 regulates WNT signaling R-HSA-8951430 7.524598e-03 2.124 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 7.524598e-03 2.124 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 7.524598e-03 2.124 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 7.351595e-03 2.134 0 0
RNA Polymerase I Transcription R-HSA-73864 7.083760e-03 2.150 0 0
Signaling by Hippo R-HSA-2028269 7.257994e-03 2.139 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 7.469555e-03 2.127 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 8.030659e-03 2.095 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 8.498973e-03 2.071 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 8.902811e-03 2.050 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 8.822417e-03 2.054 1 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 9.209779e-03 2.036 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 9.405496e-03 2.027 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 9.517659e-03 2.021 0 0
PTEN Regulation R-HSA-6807070 9.610036e-03 2.017 1 0
SDK interactions R-HSA-373756 1.037664e-02 1.984 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.023211e-02 1.990 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.038835e-02 1.983 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 1.115805e-02 1.952 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 1.085620e-02 1.964 0 0
Cell-Cell communication R-HSA-1500931 1.114114e-02 1.953 1 0
Interactions of Rev with host cellular proteins R-HSA-177243 1.082242e-02 1.966 0 0
Specification of the neural plate border R-HSA-9834899 1.079831e-02 1.967 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.144382e-02 1.941 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.235522e-02 1.908 0 0
Resolution of D-Loop Structures R-HSA-5693537 1.246593e-02 1.904 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.281480e-02 1.892 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.350277e-02 1.870 0 0
Dual incision in TC-NER R-HSA-6782135 1.351532e-02 1.869 0 0
G2/M Checkpoints R-HSA-69481 1.404706e-02 1.852 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 1.557230e-02 1.808 0 0
HIV Infection R-HSA-162906 1.567089e-02 1.805 0 0
ESR-mediated signaling R-HSA-8939211 1.520658e-02 1.818 0 0
S Phase R-HSA-69242 1.781800e-02 1.749 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.787103e-02 1.748 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.802847e-02 1.744 0 0
2-LTR circle formation R-HSA-164843 1.802847e-02 1.744 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 1.816984e-02 1.741 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.816984e-02 1.741 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.922815e-02 1.716 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 2.068083e-02 1.684 0 0
Nucleotide Excision Repair R-HSA-5696398 1.911974e-02 1.719 0 0
rRNA processing R-HSA-72312 1.978964e-02 1.704 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.943666e-02 1.711 0 0
Notch-HLH transcription pathway R-HSA-350054 2.124439e-02 1.673 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 2.124439e-02 1.673 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 2.213012e-02 1.655 0 0
Late Phase of HIV Life Cycle R-HSA-162599 2.272828e-02 1.643 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 2.287793e-02 1.641 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 2.322286e-02 1.634 0 0
Apoptotic execution phase R-HSA-75153 2.398966e-02 1.620 0 0
M Phase R-HSA-68886 2.647973e-02 1.577 1 0
G2/M DNA damage checkpoint R-HSA-69473 2.499174e-02 1.602 0 0
Signaling by ALK R-HSA-201556 2.597680e-02 1.585 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.489830e-02 1.604 0 0
Protein ubiquitination R-HSA-8852135 2.705721e-02 1.568 0 0
G0 and Early G1 R-HSA-1538133 2.760764e-02 1.559 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 2.844896e-02 1.546 1 1
Integration of provirus R-HSA-162592 2.844896e-02 1.546 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 2.844896e-02 1.546 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.192860e-02 1.496 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.252069e-02 1.488 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.252069e-02 1.488 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.110023e-02 1.507 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 3.215026e-02 1.493 0 0
Chaperone Mediated Autophagy R-HSA-9613829 3.228846e-02 1.491 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 3.051347e-02 1.516 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 2.895023e-02 1.538 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.110023e-02 1.507 1 1
PKMTs methylate histone lysines R-HSA-3214841 3.215026e-02 1.493 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.110023e-02 1.507 0 0
Signaling by NOTCH1 R-HSA-1980143 2.924409e-02 1.534 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 3.306326e-02 1.481 0 0
Deubiquitination R-HSA-5688426 3.314272e-02 1.480 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 3.435710e-02 1.464 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.487737e-02 1.457 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 3.762396e-02 1.425 0 0
TCF dependent signaling in response to WNT R-HSA-201681 3.840205e-02 1.416 1 0
Nuclear import of Rev protein R-HSA-180746 3.894657e-02 1.410 0 0
Regulation of PTEN localization R-HSA-8948747 4.147266e-02 1.382 0 0
Recycling of eIF2:GDP R-HSA-72731 4.147266e-02 1.382 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 4.346834e-02 1.362 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 4.346834e-02 1.362 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 4.346834e-02 1.362 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 4.346834e-02 1.362 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 4.346834e-02 1.362 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 4.186015e-02 1.378 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 4.186015e-02 1.378 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 4.186015e-02 1.378 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.582976e-02 1.339 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 4.346834e-02 1.362 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 4.186015e-02 1.378 0 0
HIV elongation arrest and recovery R-HSA-167287 4.710164e-02 1.327 0 0
Pausing and recovery of HIV elongation R-HSA-167290 4.710164e-02 1.327 0 0
Regulation of TP53 Degradation R-HSA-6804757 4.798639e-02 1.319 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 4.809010e-02 1.318 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 4.961991e-02 1.304 0 0
Early Phase of HIV Life Cycle R-HSA-162594 4.982757e-02 1.303 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 5.593765e-02 1.252 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 5.593765e-02 1.252 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 5.816968e-02 1.235 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 5.816968e-02 1.235 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 5.273164e-02 1.278 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 5.875357e-02 1.231 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 5.643715e-02 1.248 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 5.816968e-02 1.235 0 0
Mitotic Prometaphase R-HSA-68877 5.892813e-02 1.230 1 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 5.593765e-02 1.252 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 5.816968e-02 1.235 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 5.593765e-02 1.252 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 5.593765e-02 1.252 0 0
NRAGE signals death through JNK R-HSA-193648 5.829614e-02 1.234 0 0
HDACs deacetylate histones R-HSA-3214815 5.392217e-02 1.268 0 0
Cellular Senescence R-HSA-2559583 5.430200e-02 1.265 0 0
Diseases of DNA repair R-HSA-9675135 5.643715e-02 1.248 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 5.829614e-02 1.234 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 5.296718e-02 1.276 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 6.101397e-02 1.215 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.220973e-02 1.206 1 1
Nuclear Envelope Breakdown R-HSA-2980766 6.289204e-02 1.201 0 0
Mitotic Anaphase R-HSA-68882 6.297283e-02 1.201 0 0
DNA Double Strand Break Response R-HSA-5693606 6.333007e-02 1.198 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 6.386841e-02 1.195 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 6.386841e-02 1.195 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 6.430383e-02 1.192 0 0
ALK mutants bind TKIs R-HSA-9700645 6.430383e-02 1.192 0 0
Unwinding of DNA R-HSA-176974 6.430383e-02 1.192 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 6.516920e-02 1.186 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 6.516920e-02 1.186 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 6.536833e-02 1.185 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 6.780325e-02 1.169 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 6.979290e-02 1.156 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 6.979290e-02 1.156 0 0
HIV Transcription Elongation R-HSA-167169 6.979290e-02 1.156 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 6.979290e-02 1.156 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 7.296563e-02 1.137 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 7.296563e-02 1.137 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 7.747245e-02 1.111 0 0
Diseases of mitotic cell cycle R-HSA-9675126 7.197862e-02 1.143 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 7.918032e-02 1.101 0 0
Post-translational protein phosphorylation R-HSA-8957275 7.633601e-02 1.117 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 7.672584e-02 1.115 0 0
Nuclear RNA decay R-HSA-9930044 7.918032e-02 1.101 0 0
Mitotic Spindle Checkpoint R-HSA-69618 8.483521e-02 1.071 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 7.918032e-02 1.101 0 0
MTF1 activates gene expression R-HSA-5660489 7.672584e-02 1.115 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 7.672584e-02 1.115 0 0
Disorders of Developmental Biology R-HSA-9675151 7.745325e-02 1.111 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.200835e-02 1.143 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.918032e-02 1.101 0 0
PKR-mediated signaling R-HSA-9833482 7.602398e-02 1.119 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 8.677121e-02 1.062 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 8.766673e-02 1.057 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 8.814936e-02 1.055 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 8.814936e-02 1.055 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 8.934473e-02 1.049 0 0
Acyl chain remodelling of PS R-HSA-1482801 8.934473e-02 1.049 0 0
Neurexins and neuroligins R-HSA-6794361 9.001434e-02 1.046 0 0
Mitotic Prophase R-HSA-68875 9.073523e-02 1.042 0 0
Potential therapeutics for SARS R-HSA-9679191 9.408407e-02 1.026 0 0
Inositol phosphate metabolism R-HSA-1483249 9.465554e-02 1.024 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 9.474669e-02 1.023 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 9.474669e-02 1.023 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 9.496733e-02 1.022 0 0
Meiotic synapsis R-HSA-1221632 9.653328e-02 1.015 0 0
Myogenesis R-HSA-525793 9.875268e-02 1.005 0 0
NrCAM interactions R-HSA-447038 9.950734e-02 1.002 0 0
Mismatch Repair R-HSA-5358508 9.951553e-02 1.002 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 9.951553e-02 1.002 0 0
Ub-specific processing proteases R-HSA-5689880 9.972209e-02 1.001 0 0
Meiosis R-HSA-1500620 1.011910e-01 0.995 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.031007e-01 0.987 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 1.031007e-01 0.987 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 1.238811e-01 0.907 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 1.115223e-01 0.953 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.086371e-01 0.964 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 1.189827e-01 0.925 0 0
Formation of the Early Elongation Complex R-HSA-113418 1.189827e-01 0.925 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 1.200382e-01 0.921 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.176426e-01 0.929 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.238949e-01 0.907 0 0
DARPP-32 events R-HSA-180024 1.297726e-01 0.887 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.238949e-01 0.907 0 0
Separation of Sister Chromatids R-HSA-2467813 1.047516e-01 0.980 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.119412e-01 0.951 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.144011e-01 0.942 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.238811e-01 0.907 0 0
Regulation of gene expression in beta cells R-HSA-210745 1.297726e-01 0.887 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.230829e-01 0.910 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.209132e-01 0.918 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 1.238811e-01 0.907 0 0
Pervasive developmental disorders R-HSA-9005895 1.230829e-01 0.910 0 0
Disorders of Nervous System Development R-HSA-9697154 1.230829e-01 0.910 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.230829e-01 0.910 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.200382e-01 0.921 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.248625e-01 0.904 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.046431e-01 0.980 0 0
Death Receptor Signaling R-HSA-73887 1.100705e-01 0.958 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.301675e-01 0.885 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 1.303530e-01 0.885 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.368256e-01 0.864 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.406113e-01 0.852 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.406113e-01 0.852 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.406113e-01 0.852 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.406113e-01 0.852 0 0
Defective Mismatch Repair Associated With PMS2 R-HSA-5632987 1.406113e-01 0.852 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.406113e-01 0.852 0 0
Defective Mismatch Repair Associated With MLH1 R-HSA-5545483 1.406113e-01 0.852 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.406113e-01 0.852 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.406113e-01 0.852 0 0
UNC93B1 deficiency - HSE R-HSA-5602415 1.406113e-01 0.852 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.406113e-01 0.852 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.406113e-01 0.852 0 0
Autointegration results in viral DNA circles R-HSA-177539 1.494940e-01 0.825 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.577200e-01 0.802 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.760413e-01 0.754 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 1.760413e-01 0.754 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 1.510461e-01 0.821 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.409879e-01 0.851 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 1.799366e-01 0.745 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 1.799366e-01 0.745 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 1.769782e-01 0.752 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.492709e-01 0.826 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.844752e-01 0.734 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.814742e-01 0.741 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.814742e-01 0.741 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.659027e-01 0.780 0 0
Activation of the pre-replicative complex R-HSA-68962 1.409879e-01 0.851 0 0
Generation of second messenger molecules R-HSA-202433 1.502442e-01 0.823 0 0
Aggrephagy R-HSA-9646399 1.502442e-01 0.823 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.558531e-01 0.807 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 1.652637e-01 0.782 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.502442e-01 0.823 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.664835e-01 0.779 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 1.400375e-01 0.854 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.666919e-01 0.778 0 0
Neurofascin interactions R-HSA-447043 1.494940e-01 0.825 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.760413e-01 0.754 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.577659e-01 0.802 0 0
Smooth Muscle Contraction R-HSA-445355 1.844752e-01 0.734 0 0
tRNA processing in the nucleus R-HSA-6784531 1.664835e-01 0.779 0 0
CHL1 interactions R-HSA-447041 1.760357e-01 0.754 0 0
DNA strand elongation R-HSA-69190 1.646128e-01 0.784 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.745001e-01 0.758 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.586138e-01 0.800 0 0
Host Interactions of HIV factors R-HSA-162909 1.700300e-01 0.769 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 1.745001e-01 0.758 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 1.494940e-01 0.825 0 0
Protein methylation R-HSA-8876725 1.760413e-01 0.754 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.586138e-01 0.800 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 1.646128e-01 0.784 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 1.760357e-01 0.754 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.760357e-01 0.754 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 1.760357e-01 0.754 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.606703e-01 0.794 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 1.409879e-01 0.851 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 1.760357e-01 0.754 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 1.760357e-01 0.754 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.760413e-01 0.754 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.492709e-01 0.826 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.492709e-01 0.826 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.492709e-01 0.826 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.492709e-01 0.826 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.430473e-01 0.845 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.401340e-01 0.853 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 1.400375e-01 0.854 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 1.577200e-01 0.802 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.492709e-01 0.826 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 1.731976e-01 0.761 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 1.896812e-01 0.722 1 1
Translation initiation complex formation R-HSA-72649 1.946798e-01 0.711 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.949137e-01 0.710 0 0
Phosphorylation of the APC/C R-HSA-176412 1.949137e-01 0.710 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 1.949137e-01 0.710 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.949137e-01 0.710 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 1.950232e-01 0.710 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 1.950232e-01 0.710 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.950232e-01 0.710 0 0
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) R-HSA-5619039 2.033246e-01 0.692 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.033246e-01 0.692 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.033246e-01 0.692 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 2.614650e-01 0.583 0 0
HHAT G278V doesn't palmitoylate Hh-Np R-HSA-5658034 2.614650e-01 0.583 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 2.614650e-01 0.583 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 2.614650e-01 0.583 0 0
PLC-gamma1 signalling R-HSA-167021 3.153655e-01 0.501 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 3.153655e-01 0.501 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.153655e-01 0.501 0 0
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023 3.153655e-01 0.501 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.153655e-01 0.501 0 0
WNT mediated activation of DVL R-HSA-201688 2.308540e-01 0.637 1 1
Activated NTRK2 signals through PLCG1 R-HSA-9026527 3.653353e-01 0.437 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 3.653353e-01 0.437 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 3.653353e-01 0.437 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 3.653353e-01 0.437 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 3.653353e-01 0.437 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 3.653353e-01 0.437 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 2.142515e-01 0.669 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 4.116606e-01 0.385 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 4.116606e-01 0.385 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 4.116606e-01 0.385 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 4.116606e-01 0.385 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.339718e-01 0.631 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.339718e-01 0.631 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 2.539953e-01 0.595 0 0
PKA activation R-HSA-163615 2.539953e-01 0.595 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 2.539953e-01 0.595 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 2.742463e-01 0.562 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.742463e-01 0.562 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 3.418144e-01 0.466 0 0
Scavenging by Class F Receptors R-HSA-3000484 3.418144e-01 0.466 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 4.546071e-01 0.342 0 0
Phosphorylation of Emi1 R-HSA-176417 4.546071e-01 0.342 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 4.546071e-01 0.342 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 2.423473e-01 0.616 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 3.689589e-01 0.433 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 3.151485e-01 0.501 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 3.151485e-01 0.501 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 3.151485e-01 0.501 0 0
Late endosomal microautophagy R-HSA-9615710 2.752018e-01 0.560 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 2.290311e-01 0.640 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 3.356693e-01 0.474 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 3.356693e-01 0.474 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.356693e-01 0.474 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 4.944211e-01 0.306 0 0
Defective CHST3 causes SEDCJD R-HSA-3595172 4.944211e-01 0.306 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 3.047560e-01 0.516 0 0
Deadenylation of mRNA R-HSA-429947 3.968215e-01 0.401 0 0
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782 5.313308e-01 0.275 0 0
Defective CHSY1 causes TPBS R-HSA-3595177 5.313308e-01 0.275 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 5.313308e-01 0.275 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.747448e-01 0.561 0 0
Regulation of PTEN stability and activity R-HSA-8948751 3.178286e-01 0.498 1 1
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 3.178286e-01 0.498 0 0
Dual Incision in GG-NER R-HSA-5696400 3.765889e-01 0.424 0 0
Long-term potentiation R-HSA-9620244 4.169030e-01 0.380 0 0
Centrosome maturation R-HSA-380287 2.963049e-01 0.528 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 3.889969e-01 0.410 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 3.889969e-01 0.410 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 4.965078e-01 0.304 0 0
phospho-PLA2 pathway R-HSA-111995 5.655480e-01 0.248 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 5.655480e-01 0.248 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 5.655480e-01 0.248 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 4.504018e-01 0.346 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 4.504018e-01 0.346 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 4.504018e-01 0.346 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 4.532882e-01 0.344 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 4.765327e-01 0.322 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 5.086478e-01 0.294 0 0
HIV Transcription Initiation R-HSA-167161 5.086478e-01 0.294 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 5.086478e-01 0.294 0 0
AURKA Activation by TPX2 R-HSA-8854518 4.894631e-01 0.310 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 5.647577e-01 0.248 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 5.397707e-01 0.268 0 0
Formation of a pool of free 40S subunits R-HSA-72689 5.518038e-01 0.258 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 5.698587e-01 0.244 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 5.838906e-01 0.234 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 5.957544e-01 0.225 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 5.957544e-01 0.225 0 0
Transcription of the HIV genome R-HSA-167172 2.230322e-01 0.652 0 0
Signaling by EGFR in Cancer R-HSA-1643713 4.367610e-01 0.360 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.523337e-01 0.258 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.523337e-01 0.258 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 5.859788e-01 0.232 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 3.275136e-01 0.485 0 0
mRNA Capping R-HSA-72086 2.752018e-01 0.560 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 5.647577e-01 0.248 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 3.378845e-01 0.471 0 0
Termination of translesion DNA synthesis R-HSA-5656169 4.946414e-01 0.306 0 0
DNA Damage Bypass R-HSA-73893 4.332345e-01 0.363 0 0
Signaling by RAF1 mutants R-HSA-9656223 5.086478e-01 0.294 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 5.698587e-01 0.244 0 0
Signaling downstream of RAS mutants R-HSA-9649948 5.844840e-01 0.233 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 5.844840e-01 0.233 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 5.844840e-01 0.233 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 2.375612e-01 0.624 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 3.150816e-01 0.502 0 0
COPI-mediated anterograde transport R-HSA-6807878 5.623204e-01 0.250 0 0
Extension of Telomeres R-HSA-180786 5.731395e-01 0.242 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 4.367610e-01 0.360 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 5.655480e-01 0.248 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 4.766094e-01 0.322 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.217559e-01 0.654 1 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 3.653353e-01 0.437 0 0
Regulation of gap junction activity R-HSA-191650 3.653353e-01 0.437 0 0
NF-kB is activated and signals survival R-HSA-209560 3.143101e-01 0.503 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 2.539953e-01 0.595 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 4.103937e-01 0.387 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 5.655480e-01 0.248 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.121448e-01 0.673 1 0
Ca-dependent events R-HSA-111996 5.243317e-01 0.280 0 0
Post NMDA receptor activation events R-HSA-438064 5.906936e-01 0.229 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 3.418144e-01 0.466 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 3.442043e-01 0.463 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 4.563583e-01 0.341 0 0
Formation of the posterior neural plate R-HSA-9832991 2.865575e-01 0.543 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.116606e-01 0.385 0 0
Activation of AKT2 R-HSA-165158 4.116606e-01 0.385 0 0
Killing mechanisms R-HSA-9664420 4.473708e-01 0.349 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 4.473708e-01 0.349 0 0
PTK6 Expression R-HSA-8849473 5.313308e-01 0.275 0 0
Tight junction interactions R-HSA-420029 4.169030e-01 0.380 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 3.045039e-01 0.516 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 2.181290e-01 0.661 0 0
Intraflagellar transport R-HSA-5620924 4.185454e-01 0.378 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 4.756616e-01 0.323 0 0
Signaling by RAS mutants R-HSA-6802949 5.844840e-01 0.233 0 0
DAG and IP3 signaling R-HSA-1489509 5.698587e-01 0.244 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 2.032347e-01 0.692 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 4.116606e-01 0.385 0 0
Toxicity of botulinum toxin type E (botE) R-HSA-5250992 4.546071e-01 0.342 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 4.944211e-01 0.306 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 4.944211e-01 0.306 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 2.641321e-01 0.578 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 2.128155e-01 0.672 0 0
Stabilization of p53 R-HSA-69541 4.602911e-01 0.337 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 4.081433e-01 0.389 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.731395e-01 0.242 0 0
Cilium Assembly R-HSA-5617833 3.245626e-01 0.489 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 2.262704e-01 0.645 0 0
Chaperonin-mediated protein folding R-HSA-390466 5.906936e-01 0.229 1 0
PKA-mediated phosphorylation of CREB R-HSA-111931 3.151485e-01 0.501 0 0
Selective autophagy R-HSA-9663891 2.060203e-01 0.686 1 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 5.400296e-01 0.268 0 0
Clathrin-mediated endocytosis R-HSA-8856828 5.614966e-01 0.251 0 0
Signaling by WNT R-HSA-195721 2.363153e-01 0.627 1 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.536390e-01 0.596 0 0
DNA Replication Pre-Initiation R-HSA-69002 4.346972e-01 0.362 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 2.339718e-01 0.631 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 4.563583e-01 0.341 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.742463e-01 0.562 0 0
p75NTR signals via NF-kB R-HSA-193639 4.218085e-01 0.375 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.033246e-01 0.692 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 2.142515e-01 0.669 0 0
Reelin signalling pathway R-HSA-8866376 4.116606e-01 0.385 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 3.143101e-01 0.503 0 0
Sodium/Calcium exchangers R-HSA-425561 3.143101e-01 0.503 0 0
Metalloprotease DUBs R-HSA-5689901 2.262704e-01 0.645 0 0
Cam-PDE 1 activation R-HSA-111957 4.546071e-01 0.342 0 0
PDE3B signalling R-HSA-165160 4.546071e-01 0.342 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 4.546071e-01 0.342 0 0
PKB-mediated events R-HSA-109703 4.546071e-01 0.342 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.170263e-01 0.663 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.918993e-01 0.535 0 0
G2/M DNA replication checkpoint R-HSA-69478 4.944211e-01 0.306 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 3.596075e-01 0.444 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 3.968215e-01 0.401 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 3.968215e-01 0.401 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 5.313308e-01 0.275 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 5.313308e-01 0.275 0 0
Switching of origins to a post-replicative state R-HSA-69052 2.747448e-01 0.561 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 4.965078e-01 0.304 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 4.965078e-01 0.304 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 5.655480e-01 0.248 0 0
PKA activation in glucagon signalling R-HSA-164378 5.200090e-01 0.284 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 4.946414e-01 0.306 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 5.427644e-01 0.265 0 0
Budding and maturation of HIV virion R-HSA-162588 5.315298e-01 0.274 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 5.051335e-01 0.297 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 5.859788e-01 0.232 0 0
Polo-like kinase mediated events R-HSA-156711 5.200090e-01 0.284 0 0
HATs acetylate histones R-HSA-3214847 4.541063e-01 0.343 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 3.004677e-01 0.522 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 5.138079e-01 0.289 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 3.561571e-01 0.448 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 5.523337e-01 0.258 0 0
Synthesis of DNA R-HSA-69239 2.954414e-01 0.530 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 5.659123e-01 0.247 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 4.438006e-01 0.353 0 0
Assembly of the pre-replicative complex R-HSA-68867 5.196609e-01 0.284 0 0
Membrane Trafficking R-HSA-199991 5.590567e-01 0.253 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 2.308540e-01 0.637 0 0
NRIF signals cell death from the nucleus R-HSA-205043 3.956497e-01 0.403 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 4.766094e-01 0.322 0 0
Diseases of Immune System R-HSA-5260271 4.766094e-01 0.322 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 5.492474e-01 0.260 0 0
Oncogene Induced Senescence R-HSA-2559585 3.935274e-01 0.405 0 0
Negative regulation of MET activity R-HSA-6807004 5.647577e-01 0.248 0 0
HDMs demethylate histones R-HSA-3214842 2.104817e-01 0.677 0 0
RMTs methylate histone arginines R-HSA-3214858 2.052439e-01 0.688 0 0
G2/M Transition R-HSA-69275 3.873407e-01 0.412 0 0
NGF-stimulated transcription R-HSA-9031628 4.185454e-01 0.378 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 5.655480e-01 0.248 0 0
Mitotic G2-G2/M phases R-HSA-453274 4.023933e-01 0.395 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 5.917547e-01 0.228 0 0
Post-translational protein modification R-HSA-597592 4.868767e-01 0.313 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 5.647577e-01 0.248 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 4.116606e-01 0.385 0 0
TCR signaling R-HSA-202403 4.446946e-01 0.352 0 0
Lagging Strand Synthesis R-HSA-69186 5.859788e-01 0.232 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.946414e-01 0.306 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 4.766094e-01 0.322 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 4.766094e-01 0.322 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 2.752018e-01 0.560 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 3.791217e-01 0.421 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 2.142515e-01 0.669 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 4.116606e-01 0.385 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 3.143101e-01 0.503 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 2.918993e-01 0.535 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 3.765578e-01 0.424 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 5.313308e-01 0.275 0 0
TGFBR3 PTM regulation R-HSA-9839383 5.655480e-01 0.248 0 0
Transport of connexons to the plasma membrane R-HSA-190872 5.200090e-01 0.284 0 0
L1CAM interactions R-HSA-373760 5.234909e-01 0.281 1 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 5.668544e-01 0.247 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 5.859788e-01 0.232 0 0
Co-stimulation by CD28 R-HSA-389356 4.185454e-01 0.378 0 0
Signaling by NOTCH R-HSA-157118 3.300937e-01 0.481 0 0
Regulation of beta-cell development R-HSA-186712 5.731395e-01 0.242 0 0
Protein-protein interactions at synapses R-HSA-6794362 2.765479e-01 0.558 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.855568e-01 0.314 0 0
G1/S Transition R-HSA-69206 2.684965e-01 0.571 0 0
Interferon Signaling R-HSA-913531 5.693624e-01 0.245 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 3.426143e-01 0.465 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.426143e-01 0.465 0 0
Kinesins R-HSA-983189 4.107173e-01 0.386 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 4.194593e-01 0.377 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 5.668544e-01 0.247 0 0
The NLRP3 inflammasome R-HSA-844456 5.427644e-01 0.265 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.121472e-01 0.506 0 0
Ephrin signaling R-HSA-3928664 2.539953e-01 0.595 0 0
PERK regulates gene expression R-HSA-381042 3.935274e-01 0.405 0 0
Reproduction R-HSA-1474165 5.479817e-01 0.261 0 0
Apoptosis R-HSA-109581 4.970436e-01 0.304 0 0
Activation of BH3-only proteins R-HSA-114452 5.132717e-01 0.290 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 2.170263e-01 0.663 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 3.064412e-01 0.514 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 3.653353e-01 0.437 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 2.586876e-01 0.587 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 2.586876e-01 0.587 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 4.116606e-01 0.385 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 4.116606e-01 0.385 0 0
Activation of RAC1 R-HSA-428540 3.143101e-01 0.503 0 0
TGFBR3 expression R-HSA-9839394 2.104817e-01 0.677 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 3.689589e-01 0.433 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 4.218085e-01 0.375 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 3.765578e-01 0.424 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.563583e-01 0.341 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 5.655480e-01 0.248 0 0
Sodium/Proton exchangers R-HSA-425986 5.655480e-01 0.248 0 0
EPH-Ephrin signaling R-HSA-2682334 3.693894e-01 0.433 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.329706e-01 0.364 0 0
Formation of definitive endoderm R-HSA-9823730 2.946532e-01 0.531 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 3.004677e-01 0.522 0 0
Generic Transcription Pathway R-HSA-212436 2.096694e-01 0.678 1 0
SARS-CoV-2-host interactions R-HSA-9705683 5.117569e-01 0.291 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 2.865575e-01 0.543 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 3.150816e-01 0.502 0 0
Signaling by ERBB2 R-HSA-1227986 4.107173e-01 0.386 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 3.561571e-01 0.448 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 4.380496e-01 0.358 0 0
Programmed Cell Death R-HSA-5357801 5.374417e-01 0.270 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.019800e-01 0.695 0 0
NGF processing R-HSA-167060 3.153655e-01 0.501 0 0
Expression and Processing of Neurotrophins R-HSA-9036866 3.153655e-01 0.501 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 2.308540e-01 0.637 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 2.865575e-01 0.543 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 4.116606e-01 0.385 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 3.143101e-01 0.503 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 4.546071e-01 0.342 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 4.546071e-01 0.342 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.946532e-01 0.531 0 0
Nef and signal transduction R-HSA-164944 4.944211e-01 0.306 0 0
Formation of the anterior neural plate R-HSA-9823739 4.218085e-01 0.375 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 4.218085e-01 0.375 0 0
Uptake and function of anthrax toxins R-HSA-5210891 4.965078e-01 0.304 0 0
Gastrulation R-HSA-9758941 3.885896e-01 0.411 0 0
Influenza Infection R-HSA-168255 5.350765e-01 0.272 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 5.838906e-01 0.234 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.539953e-01 0.595 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 5.132717e-01 0.290 0 0
Signaling by TGFB family members R-HSA-9006936 2.800581e-01 0.553 0 0
Cellular response to mitochondrial stress R-HSA-9840373 2.308540e-01 0.637 0 0
Regulation of gene expression in early pancreatic precursor cells R-HSA-210747 2.865575e-01 0.543 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.539953e-01 0.595 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.539953e-01 0.595 0 0
CD28 dependent Vav1 pathway R-HSA-389359 3.689589e-01 0.433 0 0
Signaling by PDGFR in disease R-HSA-9671555 3.356693e-01 0.474 0 0
Adrenoceptors R-HSA-390696 5.655480e-01 0.248 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 5.655480e-01 0.248 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 4.107173e-01 0.386 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.742463e-01 0.562 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 4.367610e-01 0.360 0 0
Gene Silencing by RNA R-HSA-211000 4.146689e-01 0.382 0 0
Semaphorin interactions R-HSA-373755 2.948718e-01 0.530 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 3.143101e-01 0.503 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.946532e-01 0.531 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 3.356693e-01 0.474 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.563583e-01 0.341 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 5.655480e-01 0.248 0 0
Maturation of nucleoprotein R-HSA-9694631 5.427644e-01 0.265 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 2.339718e-01 0.631 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 4.169030e-01 0.380 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 5.859788e-01 0.232 0 0
Signaling by TGFBR3 R-HSA-9839373 3.889969e-01 0.410 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 3.418144e-01 0.466 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 5.132717e-01 0.290 0 0
SARS-CoV-2 Infection R-HSA-9694516 5.226826e-01 0.282 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 5.465020e-01 0.262 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 3.150816e-01 0.502 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 4.473708e-01 0.349 0 0
Nephron development R-HSA-9831926 5.200090e-01 0.284 0 0
SARS-CoV Infections R-HSA-9679506 4.379614e-01 0.359 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 2.742463e-01 0.562 0 0
Synthesis and processing of ENV and VPU R-HSA-171286 2.614650e-01 0.583 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 3.689589e-01 0.433 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 3.689589e-01 0.433 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 4.326220e-01 0.364 0 0
XBP1(S) activates chaperone genes R-HSA-381038 5.797833e-01 0.237 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 4.765327e-01 0.322 0 0
FOXO-mediated transcription R-HSA-9614085 5.932003e-01 0.227 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 5.599217e-01 0.252 0 0
Unfolded Protein Response (UPR) R-HSA-381119 4.032322e-01 0.394 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 3.418144e-01 0.466 0 0
Sema4D in semaphorin signaling R-HSA-400685 4.169030e-01 0.380 0 0
Interleukin-12 family signaling R-HSA-447115 5.906936e-01 0.229 0 0
G alpha (12/13) signalling events R-HSA-416482 4.761418e-01 0.322 0 0
G-protein beta:gamma signalling R-HSA-397795 5.668544e-01 0.247 0 0
Response to metal ions R-HSA-5660526 4.722844e-01 0.326 0 0
DNA Damage Reversal R-HSA-73942 4.218085e-01 0.375 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 4.116606e-01 0.385 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 4.602911e-01 0.337 1 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 5.972689e-01 0.224 0 0
ARMS-mediated activation R-HSA-170984 5.972689e-01 0.224 0 0
Lipophagy R-HSA-9613354 5.972689e-01 0.224 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 5.972689e-01 0.224 0 0
Calcineurin activates NFAT R-HSA-2025928 5.972689e-01 0.224 0 0
Toxicity of botulinum toxin type A (botA) R-HSA-5250968 5.972689e-01 0.224 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 5.972689e-01 0.224 0 0
p75NTR regulates axonogenesis R-HSA-193697 5.972689e-01 0.224 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 5.972689e-01 0.224 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 5.972689e-01 0.224 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 5.972689e-01 0.224 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 5.972689e-01 0.224 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 5.972689e-01 0.224 0 0
Interleukin-1 processing R-HSA-448706 5.972689e-01 0.224 0 0
Regulated proteolysis of p75NTR R-HSA-193692 5.972689e-01 0.224 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 5.988167e-01 0.223 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 5.988167e-01 0.223 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 6.004936e-01 0.221 0 0
eNOS activation R-HSA-203615 6.004936e-01 0.221 0 0
Mitophagy R-HSA-5205647 6.004936e-01 0.221 1 0
Calnexin/calreticulin cycle R-HSA-901042 6.004936e-01 0.221 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 6.064232e-01 0.217 0 0
Interleukin-12 signaling R-HSA-9020591 6.114225e-01 0.214 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 6.114985e-01 0.214 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 6.114985e-01 0.214 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 6.114985e-01 0.214 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 6.114985e-01 0.214 0 0
Metal ion SLC transporters R-HSA-425410 6.128484e-01 0.213 0 0
Signaling by VEGF R-HSA-194138 6.161467e-01 0.210 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 6.166546e-01 0.210 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.229763e-01 0.206 0 0
FGFR2 alternative splicing R-HSA-6803529 6.260913e-01 0.203 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 6.260913e-01 0.203 0 0
Degradation of CDH1 R-HSA-9766229 6.265721e-01 0.203 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 6.265721e-01 0.203 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 6.265721e-01 0.203 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 6.266756e-01 0.203 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 6.266756e-01 0.203 0 0
Receptor Mediated Mitophagy R-HSA-8934903 6.266756e-01 0.203 1 1
Regulation of the apoptosome activity R-HSA-9627069 6.266756e-01 0.203 0 0
Formation of apoptosome R-HSA-111458 6.266756e-01 0.203 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 6.266756e-01 0.203 0 0
DNA replication initiation R-HSA-68952 6.266756e-01 0.203 0 0
Regulation of CDH11 function R-HSA-9762292 6.266756e-01 0.203 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 6.266756e-01 0.203 0 0
Pexophagy R-HSA-9664873 6.266756e-01 0.203 0 0
CASP4 inflammasome assembly R-HSA-9948001 6.266756e-01 0.203 0 0
Interleukin-27 signaling R-HSA-9020956 6.266756e-01 0.203 0 0
Maturation of spike protein R-HSA-9683686 6.266756e-01 0.203 0 0
CaM pathway R-HSA-111997 6.323670e-01 0.199 0 0
Calmodulin induced events R-HSA-111933 6.323670e-01 0.199 0 0
RUNX2 regulates bone development R-HSA-8941326 6.323670e-01 0.199 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 6.409012e-01 0.193 0 0
IRE1alpha activates chaperones R-HSA-381070 6.429929e-01 0.192 0 0
DNA Replication R-HSA-69306 6.433559e-01 0.192 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 6.447065e-01 0.191 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 6.449873e-01 0.190 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 6.449873e-01 0.190 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 6.449873e-01 0.190 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 6.476264e-01 0.189 0 0
Degradation of DVL R-HSA-4641258 6.476264e-01 0.189 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 6.476264e-01 0.189 0 0
Macroautophagy R-HSA-1632852 6.506883e-01 0.187 1 0
Protein folding R-HSA-391251 6.529728e-01 0.185 1 0
Meiotic recombination R-HSA-912446 6.530727e-01 0.185 0 0
ChREBP activates metabolic gene expression R-HSA-163765 6.539366e-01 0.184 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 6.539366e-01 0.184 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 6.539366e-01 0.184 0 0
Signaling by APC mutants R-HSA-4839744 6.539366e-01 0.184 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 6.539366e-01 0.184 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 6.539366e-01 0.184 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 6.539366e-01 0.184 0 0
Ionotropic activity of kainate receptors R-HSA-451306 6.539366e-01 0.184 0 0
vRNP Assembly R-HSA-192905 6.539366e-01 0.184 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 6.539366e-01 0.184 0 0
Synthesis of PI R-HSA-1483226 6.539366e-01 0.184 0 0
Bicarbonate transporters R-HSA-425381 6.539366e-01 0.184 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 6.539366e-01 0.184 0 0
PECAM1 interactions R-HSA-210990 6.539366e-01 0.184 0 0
Suppression of apoptosis R-HSA-9635465 6.539366e-01 0.184 0 0
Elastic fibre formation R-HSA-1566948 6.624300e-01 0.179 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 6.624300e-01 0.179 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 6.631192e-01 0.178 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 6.631192e-01 0.178 0 0
Complex III assembly R-HSA-9865881 6.631192e-01 0.178 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 6.631192e-01 0.178 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 6.658411e-01 0.177 0 0
Orc1 removal from chromatin R-HSA-68949 6.658411e-01 0.177 0 0
Autophagy R-HSA-9612973 6.662748e-01 0.176 1 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 6.681777e-01 0.175 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 6.767770e-01 0.170 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 6.782844e-01 0.169 0 0
Amino acids regulate mTORC1 R-HSA-9639288 6.782844e-01 0.169 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 6.792085e-01 0.168 0 0
DS-GAG biosynthesis R-HSA-2022923 6.792085e-01 0.168 0 0
Signaling by GSK3beta mutants R-HSA-5339716 6.792085e-01 0.168 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 6.792085e-01 0.168 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 6.792085e-01 0.168 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 6.792085e-01 0.168 0 0
Signaling by AMER1 mutants R-HSA-4839748 6.792085e-01 0.168 0 0
Signaling by AXIN mutants R-HSA-4839735 6.792085e-01 0.168 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 6.792085e-01 0.168 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 6.792085e-01 0.168 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 6.804977e-01 0.167 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 6.804977e-01 0.167 0 0
Interleukin-7 signaling R-HSA-1266695 6.804977e-01 0.167 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 6.906678e-01 0.161 0 0
Chromosome Maintenance R-HSA-73886 6.932568e-01 0.159 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 6.961876e-01 0.157 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 6.961876e-01 0.157 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 6.971362e-01 0.157 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 6.971362e-01 0.157 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 7.003020e-01 0.155 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 7.021898e-01 0.154 0 0
Signaling by NOTCH3 R-HSA-9012852 7.021898e-01 0.154 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 7.026362e-01 0.153 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 7.026362e-01 0.153 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 7.026362e-01 0.153 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 7.026362e-01 0.153 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 7.026362e-01 0.153 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 7.026362e-01 0.153 0 0
Polymerase switching R-HSA-69091 7.026362e-01 0.153 0 0
Leading Strand Synthesis R-HSA-69109 7.026362e-01 0.153 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 7.026362e-01 0.153 0 0
p75NTR recruits signalling complexes R-HSA-209543 7.026362e-01 0.153 0 0
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854 7.026362e-01 0.153 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 7.026362e-01 0.153 0 0
Regulation of IFNG signaling R-HSA-877312 7.026362e-01 0.153 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 7.026362e-01 0.153 0 0
Interleukin-35 Signalling R-HSA-8984722 7.026362e-01 0.153 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 7.041045e-01 0.152 0 0
ER to Golgi Anterograde Transport R-HSA-199977 7.042317e-01 0.152 0 0
Oncogenic MAPK signaling R-HSA-6802957 7.058613e-01 0.151 0 0
Telomere Maintenance R-HSA-157579 7.092395e-01 0.149 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 7.130501e-01 0.147 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 7.130501e-01 0.147 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.130501e-01 0.147 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 7.130501e-01 0.147 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 7.136169e-01 0.147 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 7.136510e-01 0.147 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.136510e-01 0.147 0 0
MAP2K and MAPK activation R-HSA-5674135 7.170903e-01 0.144 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 7.213049e-01 0.142 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 7.236962e-01 0.140 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 7.243543e-01 0.140 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 7.243543e-01 0.140 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 7.243543e-01 0.140 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 7.243543e-01 0.140 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 7.243543e-01 0.140 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 7.243543e-01 0.140 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 7.243543e-01 0.140 0 0
rRNA modification in the mitochondrion R-HSA-6793080 7.243543e-01 0.140 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 7.243543e-01 0.140 0 0
Maturation of nucleoprotein R-HSA-9683610 7.243543e-01 0.140 0 0
Regulation of CDH1 Function R-HSA-9764561 7.247853e-01 0.140 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 7.282563e-01 0.138 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 7.282563e-01 0.138 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 7.282563e-01 0.138 0 0
Inflammasomes R-HSA-622312 7.282563e-01 0.138 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 7.282563e-01 0.138 0 0
MTOR signalling R-HSA-165159 7.296297e-01 0.137 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 7.324198e-01 0.135 1 1
Ca2+ pathway R-HSA-4086398 7.335184e-01 0.135 0 0
Hedgehog 'off' state R-HSA-5610787 7.349724e-01 0.134 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 7.371083e-01 0.132 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 7.417280e-01 0.130 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 7.427734e-01 0.129 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 7.444875e-01 0.128 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 7.444875e-01 0.128 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 7.444875e-01 0.128 0 0
Hydrolysis of LPC R-HSA-1483115 7.444875e-01 0.128 0 0
Signaling by FGFR4 in disease R-HSA-5655291 7.444875e-01 0.128 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 7.444875e-01 0.128 0 0
Non-canonical inflammasome activation R-HSA-9686114 7.444875e-01 0.128 0 0
Signal regulatory protein family interactions R-HSA-391160 7.444875e-01 0.128 0 0
Acyl chain remodeling of CL R-HSA-1482798 7.444875e-01 0.128 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 7.523526e-01 0.124 0 0
Netrin-1 signaling R-HSA-373752 7.533916e-01 0.123 0 0
DAP12 signaling R-HSA-2424491 7.566209e-01 0.121 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 7.566209e-01 0.121 0 0
Interleukin-37 signaling R-HSA-9008059 7.566209e-01 0.121 0 0
Base Excision Repair R-HSA-73884 7.594575e-01 0.119 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 7.631512e-01 0.117 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 7.631512e-01 0.117 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 7.631512e-01 0.117 0 0
Translesion synthesis by REV1 R-HSA-110312 7.631512e-01 0.117 0 0
Telomere C-strand synthesis initiation R-HSA-174430 7.631512e-01 0.117 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 7.631512e-01 0.117 0 0
Processive synthesis on the lagging strand R-HSA-69183 7.631512e-01 0.117 0 0
DCC mediated attractive signaling R-HSA-418885 7.631512e-01 0.117 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 7.646275e-01 0.117 0 0
PLC beta mediated events R-HSA-112043 7.660924e-01 0.116 0 0
Response of endothelial cells to shear stress R-HSA-9860931 7.667514e-01 0.115 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.667514e-01 0.115 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 7.676504e-01 0.115 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 7.698191e-01 0.114 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 7.698191e-01 0.114 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.698191e-01 0.114 0 0
Cargo concentration in the ER R-HSA-5694530 7.698191e-01 0.114 0 0
Trafficking of AMPA receptors R-HSA-399719 7.698191e-01 0.114 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 7.698191e-01 0.114 0 0
Rab regulation of trafficking R-HSA-9007101 7.740344e-01 0.111 0 0
Heme signaling R-HSA-9707616 7.756265e-01 0.110 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 7.756342e-01 0.110 0 0
PCP/CE pathway R-HSA-4086400 7.788109e-01 0.109 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 7.792173e-01 0.108 0 0
Translesion synthesis by POLI R-HSA-5656121 7.804527e-01 0.108 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 7.804527e-01 0.108 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 7.804527e-01 0.108 0 0
Prolonged ERK activation events R-HSA-169893 7.804527e-01 0.108 0 0
Activation of SMO R-HSA-5635838 7.804527e-01 0.108 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 7.804527e-01 0.108 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 7.804527e-01 0.108 0 0
Virus Assembly and Release R-HSA-168268 7.804527e-01 0.108 0 0
Signaling by WNT in cancer R-HSA-4791275 7.823890e-01 0.107 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.823890e-01 0.107 0 0
Eukaryotic Translation Elongation R-HSA-156842 7.834103e-01 0.106 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 7.848514e-01 0.105 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 7.858481e-01 0.105 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 7.877037e-01 0.104 0 0
Integrin signaling R-HSA-354192 7.943518e-01 0.100 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 7.943518e-01 0.100 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.943518e-01 0.100 0 0
Cardiogenesis R-HSA-9733709 7.943518e-01 0.100 0 0
GPER1 signaling R-HSA-9634597 7.958501e-01 0.099 0 0
Translesion synthesis by POLK R-HSA-5655862 7.964912e-01 0.099 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 7.964912e-01 0.099 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 7.964912e-01 0.099 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 7.964912e-01 0.099 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 7.964912e-01 0.099 0 0
Fibronectin matrix formation R-HSA-1566977 7.964912e-01 0.099 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 7.964912e-01 0.099 0 0
Synthesis of PG R-HSA-1483148 7.964912e-01 0.099 0 0
tRNA modification in the mitochondrion R-HSA-6787450 7.964912e-01 0.099 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 7.964912e-01 0.099 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 7.964912e-01 0.099 0 0
Cellular response to hypoxia R-HSA-1234174 8.023917e-01 0.096 0 0
Gap junction trafficking and regulation R-HSA-157858 8.054586e-01 0.094 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 8.054586e-01 0.094 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 8.055104e-01 0.094 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 8.057293e-01 0.094 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.057293e-01 0.094 0 0
Miscellaneous transport and binding events R-HSA-5223345 8.057293e-01 0.094 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 8.057293e-01 0.094 0 0
Neddylation R-HSA-8951664 8.103580e-01 0.091 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 8.113590e-01 0.091 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 8.113590e-01 0.091 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 8.113590e-01 0.091 0 0
Glycogen storage diseases R-HSA-3229121 8.113590e-01 0.091 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 8.113590e-01 0.091 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 8.113590e-01 0.091 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 8.124748e-01 0.090 0 0
MHC class II antigen presentation R-HSA-2132295 8.131871e-01 0.090 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.146835e-01 0.089 0 0
Signaling by NOTCH2 R-HSA-1980145 8.165429e-01 0.088 0 0
RAF activation R-HSA-5673000 8.165429e-01 0.088 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 8.165429e-01 0.088 0 0
Gap junction assembly R-HSA-190861 8.165429e-01 0.088 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 8.165429e-01 0.088 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.165429e-01 0.088 0 0
G-protein mediated events R-HSA-112040 8.187545e-01 0.087 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 8.235346e-01 0.084 0 0
Hedgehog ligand biogenesis R-HSA-5358346 8.235346e-01 0.084 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 8.251415e-01 0.083 0 0
Apoptotic factor-mediated response R-HSA-111471 8.251415e-01 0.083 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 8.251415e-01 0.083 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 8.251415e-01 0.083 0 0
Platelet sensitization by LDL R-HSA-432142 8.251415e-01 0.083 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 8.251415e-01 0.083 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 8.265082e-01 0.083 0 0
Viral Infection Pathways R-HSA-9824446 8.267778e-01 0.083 1 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 8.268144e-01 0.083 0 0
Regulation of Apoptosis R-HSA-169911 8.268144e-01 0.083 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.268144e-01 0.083 0 0
Signaling by Hedgehog R-HSA-5358351 8.287008e-01 0.082 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 8.320220e-01 0.080 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 8.320220e-01 0.080 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 8.346296e-01 0.079 0 0
PRC2 methylates histones and DNA R-HSA-212300 8.365653e-01 0.078 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.365653e-01 0.078 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.365653e-01 0.078 0 0
Translesion Synthesis by POLH R-HSA-110320 8.379177e-01 0.077 0 0
E2F mediated regulation of DNA replication R-HSA-113510 8.379177e-01 0.077 0 0
Germ layer formation at gastrulation R-HSA-9754189 8.379177e-01 0.077 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 8.379177e-01 0.077 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 8.411906e-01 0.075 0 0
ABC-family proteins mediated transport R-HSA-382556 8.443946e-01 0.073 0 0
Glycolysis R-HSA-70171 8.443946e-01 0.073 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 8.458166e-01 0.073 0 0
Degradation of AXIN R-HSA-4641257 8.458166e-01 0.073 0 0
tRNA processing R-HSA-72306 8.460516e-01 0.073 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 8.497611e-01 0.071 0 0
Glycogen synthesis R-HSA-3322077 8.497611e-01 0.071 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 8.497611e-01 0.071 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 8.497611e-01 0.071 0 0
Acyl chain remodelling of PI R-HSA-1482922 8.497611e-01 0.071 0 0
Pregnenolone biosynthesis R-HSA-196108 8.497611e-01 0.071 0 0
Protein hydroxylation R-HSA-9629569 8.497611e-01 0.071 0 0
Signal transduction by L1 R-HSA-445144 8.497611e-01 0.071 1 1
Signaling by NODAL R-HSA-1181150 8.497611e-01 0.071 0 0
Nephrin family interactions R-HSA-373753 8.497611e-01 0.071 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 8.502186e-01 0.070 0 0
Organelle biogenesis and maintenance R-HSA-1852241 8.536791e-01 0.069 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.545895e-01 0.068 0 0
PI Metabolism R-HSA-1483255 8.558633e-01 0.068 0 0
Cellular response to starvation R-HSA-9711097 8.565568e-01 0.067 0 0
Signaling by ROBO receptors R-HSA-376176 8.574003e-01 0.067 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 8.607398e-01 0.065 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 8.607398e-01 0.065 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 8.607398e-01 0.065 0 0
Acyl chain remodelling of PG R-HSA-1482925 8.607398e-01 0.065 0 0
Signaling by EGFR R-HSA-177929 8.625428e-01 0.064 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 8.625428e-01 0.064 0 0
Adipogenesis R-HSA-9843745 8.666034e-01 0.062 0 0
Opioid Signalling R-HSA-111885 8.666280e-01 0.062 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 8.666280e-01 0.062 0 0
Signaling by NOTCH4 R-HSA-9013694 8.674317e-01 0.062 0 0
Signaling by FGFR in disease R-HSA-1226099 8.674317e-01 0.062 0 0
Neurotransmitter release cycle R-HSA-112310 8.687579e-01 0.061 0 0
Glycogen metabolism R-HSA-8982491 8.707810e-01 0.060 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 8.707810e-01 0.060 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 8.707810e-01 0.060 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 8.707810e-01 0.060 0 0
CS-GAG biosynthesis R-HSA-2022870 8.709168e-01 0.060 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 8.709168e-01 0.060 0 0
Attachment and Entry R-HSA-9694614 8.709168e-01 0.060 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 8.709168e-01 0.060 0 0
Serine metabolism R-HSA-977347 8.709168e-01 0.060 0 0
Mitochondrial calcium ion transport R-HSA-8949215 8.709168e-01 0.060 0 0
Assembly Of The HIV Virion R-HSA-175474 8.709168e-01 0.060 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 8.741809e-01 0.058 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 8.782395e-01 0.056 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 8.782395e-01 0.056 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 8.782395e-01 0.056 0 0
Maturation of spike protein R-HSA-9694548 8.782395e-01 0.056 0 0
FLT3 Signaling R-HSA-9607240 8.782395e-01 0.056 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 8.803507e-01 0.055 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 8.803507e-01 0.055 0 0
mTORC1-mediated signalling R-HSA-166208 8.803507e-01 0.055 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 8.803507e-01 0.055 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 8.803507e-01 0.055 0 0
Signaling by NTRKs R-HSA-166520 8.805103e-01 0.055 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 8.844575e-01 0.053 0 0
Translation of Structural Proteins R-HSA-9694635 8.845857e-01 0.053 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 8.846077e-01 0.053 0 0
Signaling by FGFR1 in disease R-HSA-5655302 8.852986e-01 0.053 0 0
Translation of Structural Proteins R-HSA-9683701 8.852986e-01 0.053 0 0
HCMV Early Events R-HSA-9609690 8.883026e-01 0.051 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 8.890956e-01 0.051 0 0
Interleukin receptor SHC signaling R-HSA-912526 8.890956e-01 0.051 0 0
Mitochondrial mRNA modification R-HSA-9937008 8.890956e-01 0.051 0 0
Integrin cell surface interactions R-HSA-216083 8.898577e-01 0.051 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 8.919768e-01 0.050 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.919768e-01 0.050 0 0
Nervous system development R-HSA-9675108 8.940743e-01 0.049 1 0
Sensory processing of sound R-HSA-9659379 8.949178e-01 0.048 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 8.960453e-01 0.048 1 0
TNFs bind their physiological receptors R-HSA-5669034 8.972019e-01 0.047 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 8.972019e-01 0.047 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 8.972019e-01 0.047 0 0
Neurodegenerative Diseases R-HSA-8863678 8.972019e-01 0.047 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 8.972019e-01 0.047 0 0
Defective pyroptosis R-HSA-9710421 8.982922e-01 0.047 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 8.982922e-01 0.047 0 0
Signaling by PDGF R-HSA-186797 8.991840e-01 0.046 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 8.997725e-01 0.046 0 0
Co-inhibition by PD-1 R-HSA-389948 9.013081e-01 0.045 0 0
Eukaryotic Translation Termination R-HSA-72764 9.028663e-01 0.044 0 0
Proteasome assembly R-HSA-9907900 9.042621e-01 0.044 0 0
DAP12 interactions R-HSA-2172127 9.042621e-01 0.044 0 0
EPHB-mediated forward signaling R-HSA-3928662 9.042621e-01 0.044 0 0
Cyclin D associated events in G1 R-HSA-69231 9.042621e-01 0.044 0 0
G1 Phase R-HSA-69236 9.042621e-01 0.044 0 0
Surfactant metabolism R-HSA-5683826 9.042621e-01 0.044 0 0
Gap junction trafficking R-HSA-190828 9.042621e-01 0.044 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.047161e-01 0.043 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.047161e-01 0.043 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 9.047161e-01 0.043 0 0
Axon guidance R-HSA-422475 9.070163e-01 0.042 1 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.070494e-01 0.042 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 9.088915e-01 0.041 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 9.092861e-01 0.041 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.099031e-01 0.041 0 0
Nucleosome assembly R-HSA-774815 9.099031e-01 0.041 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 9.099031e-01 0.041 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.099031e-01 0.041 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.099031e-01 0.041 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.099031e-01 0.041 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.099031e-01 0.041 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 9.099031e-01 0.041 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 9.116814e-01 0.040 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.116814e-01 0.040 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 9.116814e-01 0.040 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 9.116814e-01 0.040 0 0
Sphingolipid catabolism R-HSA-9845614 9.116814e-01 0.040 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 9.116814e-01 0.040 0 0
Platelet degranulation R-HSA-114608 9.118519e-01 0.040 0 0
Vesicle-mediated transport R-HSA-5653656 9.118919e-01 0.040 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.131687e-01 0.039 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.152315e-01 0.038 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.152315e-01 0.038 0 0
Regulation of TNFR1 signaling R-HSA-5357905 9.152315e-01 0.038 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 9.152537e-01 0.038 0 0
Packaging Of Telomere Ends R-HSA-171306 9.181380e-01 0.037 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 9.181380e-01 0.037 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.181380e-01 0.037 0 0
Triglyceride biosynthesis R-HSA-75109 9.181380e-01 0.037 0 0
Signaling by BMP R-HSA-201451 9.181380e-01 0.037 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 9.181380e-01 0.037 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.181380e-01 0.037 1 1
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 9.202629e-01 0.036 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 9.202629e-01 0.036 0 0
Recycling pathway of L1 R-HSA-437239 9.202629e-01 0.036 0 0
SARS-CoV-1 Infection R-HSA-9678108 9.210011e-01 0.036 0 0
Telomere Extension By Telomerase R-HSA-171319 9.241229e-01 0.034 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 9.241229e-01 0.034 0 0
Insulin receptor recycling R-HSA-77387 9.241229e-01 0.034 0 0
Pyroptosis R-HSA-5620971 9.241229e-01 0.034 0 0
Interleukin-1 signaling R-HSA-9020702 9.256824e-01 0.034 0 0
Regulated Necrosis R-HSA-5218859 9.267816e-01 0.033 0 0
DNA methylation R-HSA-5334118 9.296706e-01 0.032 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 9.296706e-01 0.032 0 0
Platelet calcium homeostasis R-HSA-418360 9.296706e-01 0.032 0 0
Signaling by Erythropoietin R-HSA-9006335 9.296706e-01 0.032 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.296706e-01 0.032 0 0
Glucose metabolism R-HSA-70326 9.308046e-01 0.031 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.333732e-01 0.030 0 0
COPII-mediated vesicle transport R-HSA-204005 9.343160e-01 0.030 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 9.348130e-01 0.029 0 0
Peptide chain elongation R-HSA-156902 9.352644e-01 0.029 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.377072e-01 0.028 0 0
Hedgehog 'on' state R-HSA-5632684 9.378090e-01 0.028 0 0
Metabolism of cofactors R-HSA-8978934 9.378090e-01 0.028 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 9.395797e-01 0.027 0 0
EGFR downregulation R-HSA-182971 9.395797e-01 0.027 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.395797e-01 0.027 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 9.395797e-01 0.027 0 0
Downstream signal transduction R-HSA-186763 9.395797e-01 0.027 0 0
Downstream TCR signaling R-HSA-202424 9.414105e-01 0.026 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.414653e-01 0.026 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.434109e-01 0.025 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.439981e-01 0.025 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 9.439981e-01 0.025 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.458369e-01 0.024 0 0
HCMV Infection R-HSA-9609646 9.467251e-01 0.024 0 0
Ribosome-associated quality control R-HSA-9948299 9.479971e-01 0.023 0 0
FGFR1 mutant receptor activation R-HSA-1839124 9.480936e-01 0.023 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 9.483446e-01 0.023 0 0
CS/DS degradation R-HSA-2024101 9.518898e-01 0.021 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.518898e-01 0.021 0 0
Effects of PIP2 hydrolysis R-HSA-114508 9.518898e-01 0.021 0 0
UCH proteinases R-HSA-5689603 9.528334e-01 0.021 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 9.533335e-01 0.021 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 9.533335e-01 0.021 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 9.533335e-01 0.021 0 0
HCMV Late Events R-HSA-9610379 9.536714e-01 0.021 0 0
Adaptive Immune System R-HSA-1280218 9.537339e-01 0.021 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.541760e-01 0.020 0 0
TNF signaling R-HSA-75893 9.544484e-01 0.020 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.553993e-01 0.020 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.554086e-01 0.020 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.554086e-01 0.020 1 1
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 9.554086e-01 0.020 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.554086e-01 0.020 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.554086e-01 0.020 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 9.554086e-01 0.020 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.554086e-01 0.020 0 0
NOD1/2 Signaling Pathway R-HSA-168638 9.554086e-01 0.020 0 0
Signal amplification R-HSA-392518 9.554086e-01 0.020 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.554086e-01 0.020 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.567899e-01 0.019 0 0
Synthesis of PA R-HSA-1483166 9.572355e-01 0.019 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.586702e-01 0.018 0 0
Signalling to ERKs R-HSA-187687 9.586702e-01 0.018 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.586702e-01 0.018 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.586702e-01 0.018 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.586702e-01 0.018 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 9.595242e-01 0.018 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.610247e-01 0.017 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.616935e-01 0.017 0 0
FLT3 signaling in disease R-HSA-9682385 9.616935e-01 0.017 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 9.616935e-01 0.017 0 0
GPVI-mediated activation cascade R-HSA-114604 9.616935e-01 0.017 0 0
RET signaling R-HSA-8853659 9.616935e-01 0.017 0 0
G1/S-Specific Transcription R-HSA-69205 9.616935e-01 0.017 0 0
Peroxisomal protein import R-HSA-9033241 9.623273e-01 0.017 0 0
Signaling by FGFR2 R-HSA-5654738 9.623344e-01 0.017 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 9.627627e-01 0.016 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.644113e-01 0.016 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.644958e-01 0.016 0 0
Cleavage of the damaged purine R-HSA-110331 9.644958e-01 0.016 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.644958e-01 0.016 0 0
Metabolism of folate and pterines R-HSA-196757 9.644958e-01 0.016 0 0
Interferon alpha/beta signaling R-HSA-909733 9.666559e-01 0.015 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.668341e-01 0.015 0 0
Aquaporin-mediated transport R-HSA-445717 9.668341e-01 0.015 0 0
Depurination R-HSA-73927 9.670932e-01 0.015 0 0
Circadian clock R-HSA-9909396 9.675511e-01 0.014 1 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.682455e-01 0.014 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.695007e-01 0.013 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 9.695007e-01 0.013 0 0
RAS processing R-HSA-9648002 9.695007e-01 0.013 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.695007e-01 0.013 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.695007e-01 0.013 0 0
Selenocysteine synthesis R-HSA-2408557 9.699854e-01 0.013 0 0
Signaling by PTK6 R-HSA-8848021 9.708196e-01 0.013 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 9.708196e-01 0.013 0 0
Cellular response to chemical stress R-HSA-9711123 9.709143e-01 0.013 1 0
rRNA processing in the mitochondrion R-HSA-8868766 9.717323e-01 0.012 0 0
Interleukin-2 family signaling R-HSA-451927 9.717323e-01 0.012 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 9.718082e-01 0.012 0 0
IGF1R signaling cascade R-HSA-2428924 9.726350e-01 0.012 0 0
Interleukin-1 family signaling R-HSA-446652 9.728138e-01 0.012 0 0
Viral mRNA Translation R-HSA-192823 9.729985e-01 0.012 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.732724e-01 0.012 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.738006e-01 0.012 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.738006e-01 0.012 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.743411e-01 0.011 0 0
Signal Transduction R-HSA-162582 9.749231e-01 0.011 1 0
Degradation of CRY and PER proteins R-HSA-9932298 9.757178e-01 0.011 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 9.757178e-01 0.011 0 0
Negative regulation of MAPK pathway R-HSA-5675221 9.757178e-01 0.011 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.757178e-01 0.011 0 0
Intra-Golgi traffic R-HSA-6811438 9.757178e-01 0.011 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.757178e-01 0.011 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.757178e-01 0.011 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.757178e-01 0.011 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 9.757264e-01 0.011 0 0
Activation of HOX genes during differentiation R-HSA-5619507 9.757264e-01 0.011 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.759442e-01 0.011 0 0
Kidney development R-HSA-9830369 9.774502e-01 0.010 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.774948e-01 0.010 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.774948e-01 0.010 0 0
Depyrimidination R-HSA-73928 9.774948e-01 0.010 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 9.774948e-01 0.010 0 0
Diseases of programmed cell death R-HSA-9645723 9.775381e-01 0.010 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 9.775675e-01 0.010 0 0
SARS-CoV-1-host interactions R-HSA-9692914 9.781937e-01 0.010 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.782358e-01 0.010 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.782847e-01 0.010 0 0
Signaling by FGFR4 R-HSA-5654743 9.791418e-01 0.009 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.791418e-01 0.009 0 0
Cytokine Signaling in Immune system R-HSA-1280215 9.793049e-01 0.009 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.793369e-01 0.009 0 0
Phospholipid metabolism R-HSA-1483257 9.798346e-01 0.009 1 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 9.801932e-01 0.009 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.806684e-01 0.008 0 0
Amine ligand-binding receptors R-HSA-375280 9.806684e-01 0.008 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 9.811506e-01 0.008 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 9.813299e-01 0.008 0 0
Leishmania infection R-HSA-9658195 9.816995e-01 0.008 0 0
Parasitic Infection Pathways R-HSA-9824443 9.816995e-01 0.008 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.820833e-01 0.008 0 0
Signaling by FGFR3 R-HSA-5654741 9.820833e-01 0.008 0 0
Somitogenesis R-HSA-9824272 9.820833e-01 0.008 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.833948e-01 0.007 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 9.837104e-01 0.007 0 0
Synthesis of PC R-HSA-1483191 9.846103e-01 0.007 1 1
Signaling by ERBB4 R-HSA-1236394 9.857095e-01 0.006 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.857369e-01 0.006 0 0
SLC transporter disorders R-HSA-5619102 9.863055e-01 0.006 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.865218e-01 0.006 1 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.866175e-01 0.006 0 0
PI3K Cascade R-HSA-109704 9.877490e-01 0.005 0 0
Regulation of RAS by GAPs R-HSA-5658442 9.877490e-01 0.005 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.877490e-01 0.005 0 0
The phototransduction cascade R-HSA-2514856 9.886460e-01 0.005 0 0
Signaling by FGFR R-HSA-190236 9.889506e-01 0.005 0 0
Regulation of insulin secretion R-HSA-422356 9.889506e-01 0.005 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 9.889506e-01 0.005 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 9.889506e-01 0.005 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 9.889506e-01 0.005 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.890169e-01 0.005 0 0
ABC transporter disorders R-HSA-5619084 9.890169e-01 0.005 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.891842e-01 0.005 0 0
Translation R-HSA-72766 9.896770e-01 0.005 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.897192e-01 0.004 0 0
Metabolism of proteins R-HSA-392499 9.901080e-01 0.004 1 0
PPARA activates gene expression R-HSA-1989781 9.902729e-01 0.004 0 0
Signaling by MET R-HSA-6806834 9.903776e-01 0.004 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 9.904353e-01 0.004 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 9.904353e-01 0.004 0 0
Signaling by Interleukins R-HSA-449147 9.908870e-01 0.004 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.909621e-01 0.004 0 0
Amyloid fiber formation R-HSA-977225 9.909948e-01 0.004 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.916240e-01 0.004 0 0
G alpha (z) signalling events R-HSA-418597 9.916240e-01 0.004 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 9.919205e-01 0.004 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 9.919205e-01 0.004 0 0
Leishmania phagocytosis R-HSA-9664417 9.920382e-01 0.003 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.920382e-01 0.003 0 0
Parasite infection R-HSA-9664407 9.920382e-01 0.003 0 0
Ion homeostasis R-HSA-5578775 9.922375e-01 0.003 0 0
Signaling by FGFR1 R-HSA-5654736 9.922375e-01 0.003 0 0
RSV-host interactions R-HSA-9833110 9.927619e-01 0.003 0 0
IRS-mediated signalling R-HSA-112399 9.928060e-01 0.003 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 9.931897e-01 0.003 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.933330e-01 0.003 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.937770e-01 0.003 0 0
Triglyceride metabolism R-HSA-8979227 9.938214e-01 0.003 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.938214e-01 0.003 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.939172e-01 0.003 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.939622e-01 0.003 0 0
Metabolism of polyamines R-HSA-351202 9.942740e-01 0.002 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.943314e-01 0.002 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 9.943314e-01 0.002 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 9.946690e-01 0.002 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.946935e-01 0.002 0 0
Collagen degradation R-HSA-1442490 9.946935e-01 0.002 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.946935e-01 0.002 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 9.949870e-01 0.002 0 0
MyD88-independent TLR4 cascade R-HSA-166166 9.949870e-01 0.002 0 0
ER-Phagosome pathway R-HSA-1236974 9.950622e-01 0.002 0 0
Mitochondrial protein import R-HSA-1268020 9.950823e-01 0.002 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.955687e-01 0.002 0 0
Insulin receptor signalling cascade R-HSA-74751 9.957766e-01 0.002 0 0
Ion transport by P-type ATPases R-HSA-936837 9.957766e-01 0.002 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 9.958345e-01 0.002 0 0
Signaling by Insulin receptor R-HSA-74752 9.962282e-01 0.002 0 0
Protein localization R-HSA-9609507 9.962685e-01 0.002 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.963302e-01 0.002 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.963302e-01 0.002 0 0
Muscle contraction R-HSA-397014 9.963936e-01 0.002 0 0
Transmission across Chemical Synapses R-HSA-112315 9.964143e-01 0.002 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.964745e-01 0.002 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 9.965420e-01 0.002 0 0
Nicotinate metabolism R-HSA-196807 9.966388e-01 0.001 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.966388e-01 0.001 0 0
Metabolism of steroid hormones R-HSA-196071 9.966388e-01 0.001 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.967507e-01 0.001 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.968851e-01 0.001 0 0
Integration of energy metabolism R-HSA-163685 9.969603e-01 0.001 0 0
Mitochondrial biogenesis R-HSA-1592230 9.971319e-01 0.001 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.971695e-01 0.001 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.973250e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.975211e-01 0.001 0 0
ECM proteoglycans R-HSA-3000178 9.975211e-01 0.001 0 0
Sphingolipid metabolism R-HSA-428157 9.975468e-01 0.001 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.977861e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.978074e-01 0.001 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.978713e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.980274e-01 0.001 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.980323e-01 0.001 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.981720e-01 0.001 0 0
Iron uptake and transport R-HSA-917937 9.981720e-01 0.001 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.983056e-01 0.001 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.983312e-01 0.001 0 0
Cholesterol biosynthesis R-HSA-191273 9.985454e-01 0.001 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 9.985915e-01 0.001 0 0
Toll-like Receptor Cascades R-HSA-168898 9.985983e-01 0.001 0 0
MAPK family signaling cascades R-HSA-5683057 9.986963e-01 0.001 0 0
Platelet homeostasis R-HSA-418346 9.987312e-01 0.001 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.988941e-01 0.000 0 0
Stimuli-sensing channels R-HSA-2672351 9.988941e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.990220e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.990363e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.990791e-01 0.000 0 0
Selenoamino acid metabolism R-HSA-2408522 9.994653e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.995228e-01 0.000 1 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.995703e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.996038e-01 0.000 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 9.996310e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.996310e-01 0.000 0 0
Collagen formation R-HSA-1474290 9.996310e-01 0.000 0 0
Neuronal System R-HSA-112316 9.996503e-01 0.000 0 0
G alpha (s) signalling events R-HSA-418555 9.996732e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.997065e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.997311e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.997322e-01 0.000 0 0
Neutrophil degranulation R-HSA-6798695 9.997425e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.997480e-01 0.000 0 0
Cardiac conduction R-HSA-5576891 9.998306e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.998433e-01 0.000 0 0
Interferon gamma signaling R-HSA-877300 9.998518e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.998991e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999012e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999035e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.999452e-01 0.000 0 0
Developmental Biology R-HSA-1266738 9.999493e-01 0.000 1 0
Peptide hormone metabolism R-HSA-2980736 9.999530e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999654e-01 0.000 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.999666e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999666e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999703e-01 0.000 0 0
Formation of the cornified envelope R-HSA-6809371 9.999725e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999788e-01 0.000 0 0
Ion channel transport R-HSA-983712 9.999813e-01 0.000 0 0
RAF/MAP kinase cascade R-HSA-5673001 9.999819e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999862e-01 0.000 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 9.999880e-01 0.000 0 0
Hemostasis R-HSA-109582 9.999884e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999952e-01 0.000 0 0
Developmental Cell Lineages R-HSA-9734767 9.999954e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999965e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999969e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999974e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999994e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999995e-01 0.000 0 0
Disease R-HSA-1643685 9.999998e-01 0.000 1 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999999e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.999999e-01 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Keratinization R-HSA-6805567 1.000000e+00 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.000000e+00 0.000 0 0
Immune System R-HSA-168256 1.000000e+00 0.000 0 0
G alpha (i) signalling events R-HSA-418594 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
G alpha (q) signalling events R-HSA-416476 1.000000e+00 0.000 0 0
GPCR downstream signalling R-HSA-388396 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Innate Immune System R-HSA-168249 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 1 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 1 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 -0.000 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 1.000000e+00 0.000 1 1
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways