CK1D

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0A2R8Y4L2 S158 Sugiyama HNRNPA1L3 HNRNPA1P48 TDRGSGKKRGFAFVTFDDHDsVDKIVIQKYHTVNGHNCEVR
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 S939 Sugiyama POTEF A26C1B VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE
A6NMY6 S127 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B AQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEINRVy
A6NMY6 T123 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B LKtPAQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEI
A6NMY6 T31 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B LsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAIKTKGV
A6NMY6 Y30 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B KLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAIKTKG
O00165 S192 Sugiyama HAX1 HS1BP1 VWPMDPHPRtREDNDLDsQVsQEGLGPVLQPQPKSYFKsIS
O00165 T181 Sugiyama HAX1 HS1BP1 GsQRPFHRFDDVWPMDPHPRtREDNDLDsQVsQEGLGPVLQ
O00170 S43 Sugiyama AIP XAP2 GELPDFQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELI
O00170 T48 Sugiyama AIP XAP2 FQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELIIGKKF
O00299 T222 Sugiyama CLIC1 G6 NCC27 AFRGVHRYLsNAyAREEFAstCPDDEEIELAyEQVAKALK_
O00469 S367 Sugiyama PLOD2 FDKAKHEIKTIKIVGPEENLsQAEARNMGMDFCRQDEKCDY
O00566 S171 Sugiyama MPHOSPH10 MPP10 RAENSSKsDLRKsPVFsDEDsDLDFDISKLEQQSKVQNKGQ
O00571 S70 Sugiyama DDX3X DBX DDX3 KGFyDKDSSGWsssKDKDAyssFGsRsDsRGKssFFsDRGs
O14641 S143 SIGNOR|PSP DVL2 ERtsGIGDsRPPsFHPNVsssHENLEPEtEtEsVVsLRRER
O14641 T224 SIGNOR|PSP DVL2 EStSLGDsDEEDTMSRFSSStEQssASRLLKRHRRRRKQRP
O14980 S450 Sugiyama XPO1 CRM1 VLVVENDQGEVVREFMKDTDsINLyKNMRETLVyLTHLDyV
O15055 S480 SIGNOR PER2 KIAA0347 QELTEQIHRLLLQPVPHSGSsGYGSLGSNGSHEHLMSQTSS
O15055 S662 PSP PER2 KIAA0347 NSRTGVGTHLTSLALPGKAEsVAsLTsQCsYSsTIVHVGDK
O15055 S665 PSP PER2 KIAA0347 TGVGTHLTSLALPGKAEsVAsLTsQCsYSsTIVHVGDKKPQ
O15055 S668 PSP PER2 KIAA0347 GTHLTSLALPGKAEsVAsLTsQCsYSsTIVHVGDKKPQPEL
O15055 S977 iPTMNet PER2 KIAA0347 RQPCACPATRATPPSAMGRAsPPLFQSRSSSPLQLNLLQLE
O15143 S311 Sugiyama ARPC1B ARC41 SSQRGLTARERFQNLDKKAssEGGtAAGAGLDsLHKNsVsQ
O15143 T315 Sugiyama ARPC1B ARC41 GLTARERFQNLDKKAssEGGtAAGAGLDsLHKNsVsQIsVL
O15169 S46 SIGNOR AXIN1 AXIN PGEEGELVSTDPRPASYSFCsGKGVGIKGETSTATPRRSDL
O15460 T532 Sugiyama P4HA2 UNQ290/PRO330 WVSNKWFHERGQEFLRPCGstEVD_________________
O15523 S70 Sugiyama DDX3Y DBY KGFHDKDSSGWSCSKDKDAyssFGsRDSRGKPGYFSERGSG
O43242 T48 Sugiyama PSMD3 PPPAPQDVEMKEEAAtGGGstGEADGKtAAAAAEHsQRELD
O43242 T55 Sugiyama PSMD3 VEMKEEAAtGGGstGEADGKtAAAAAEHsQRELDtVtLEDI
O43312 S322 SIGNOR|PSP MTSS1 KIAA0429 MIM RSSNLAQQAPVRLSsVSSHDsGFISQDAFQSKSPSPMPPEA
O43399 T23 Sugiyama TPD52L2 sAGQDINLNsPNKGLLsDsMtDVPVDTGVAARtPAVEGLTE
O43633 S203 Sugiyama CHMP2A BC2 CHMP2 PSTGGSLSVAAGGKKAEAAAsALADADADLEERLKNLRRD_
O43707 S447 Sugiyama ACTN4 AWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAAHQ
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43719 S702 Sugiyama HTATSF1 EDADGKEVEDADEKLFEDDDsNEKLFDEEEDssEKLFDDsD
O43719 S714 Sugiyama HTATSF1 EKLFEDDDsNEKLFDEEEDssEKLFDDsDERGTLGGFGSVE
O43823 S124 Sugiyama AKAP8 AKAP95 SKEGGRGGsGGGGEGIQDREssFRFQPFESYDSRPCLPEHN
O43847 S96 Sugiyama NRDC NRD1 SRVARLGADEsEEEGRRGsLsNAGDPEIVKsPsDPKQYRYI
O43852 S261 Sugiyama CALU RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK
O43852 S300 Sugiyama CALU NKDGKLTKEEIVDKyDLFVGsQAtDFGEALVRHDEF_____
O43852 S44 Sugiyama CALU KKDRVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQL
O43852 T303 Sugiyama CALU GKLTKEEIVDKyDLFVGsQAtDFGEALVRHDEF________
O43896 S674 Sugiyama KIF1C KIAA0706 YRKEKEEADLLLEQQRLyADsDsGDDsDKRsCEESWRLISS
O43896 S684 Sugiyama KIF1C KIAA0706 LLEQQRLyADsDsGDDsDKRsCEESWRLISSLREQLPPTTV
O60231 S112 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 EKNRSYRLLEDsEEssEEtVsRAGsSLQKKRKKRKHLRKKR
O60231 S116 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 SYRLLEDsEEssEEtVsRAGsSLQKKRKKRKHLRKKREEEE
O60264 S825 Sugiyama SMARCA5 SNF2H WCRF135 ELPNAAQAQKEEQLKIDEAEsLNDEELEEKEKLLTQGFTNW
O60664 S148 Sugiyama PLIN3 M6PRBP1 TIP47 KVsGAQEMVssAKDTVAtQLsEAVDATRGAVQSGVDKTKsV
O60664 S225 Sugiyama PLIN3 M6PRBP1 TIP47 PLTDAELARIAtsLDGFDVAsVQQQRQEQSyFVRLGsLSER
O60664 T145 Sugiyama PLIN3 M6PRBP1 TIP47 VssKVsGAQEMVssAKDTVAtQLsEAVDATRGAVQSGVDKT
O60716 S252 Sugiyama CTNND1 KIAA0384 sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL
O60841 S113 Sugiyama EIF5B IF2 KIAA0741 sKDKKKKGQKGKKQsFDDNDsEELEDKDsKSKKTAKPKVEM
O60841 S222 Sugiyama EIF5B IF2 KIAA0741 KNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAEKKERERKK
O75122 S14 Sugiyama CLASP2 KIAA0627 _______MAMGDDKsFDDEEsVDGNRPssAAsAFKVPAPKT
O75122 S974 Sugiyama CLASP2 KIAA0627 RsQEDMNEPLKRDSKKDDGDsMCGGPGMSDPRAGGDATDss
O75581 S1490 PSP LRP6 SSSSssTKGtYFPAILNPPPsPAtERsHYTMEFGYSsNsPs
O75581 T1479 SIGNOR LRP6 PYDRAHVTGASSSSSssTKGtYFPAILNPPPsPAtERsHYT
O75581 T1493 SIGNOR LRP6 SssTKGtYFPAILNPPPsPAtERsHYTMEFGYSsNsPsTHR
O75821 S217 Sugiyama EIF3G EIF3S4 PGELEPVQAtQNKtGKYVPPsLRDGAsRRGESMQPNRRADD
O75821 S223 Sugiyama EIF3G EIF3S4 VQAtQNKtGKYVPPsLRDGAsRRGESMQPNRRADDNAtIRV
O75821 T240 Sugiyama EIF3G EIF3S4 DGAsRRGESMQPNRRADDNAtIRVtNLSEDTRETDLQELFR
O75822 T157 Sugiyama EIF3J EIF3S1 PRO0391 GVNNAVyGIDAMNPSSRDDFtEFGKLLKDKITQYEKSLYYA
O95218 S153 Sugiyama ZRANB2 ZIS ZNF265 KYRGKAVGPAsILKEVEDKEsEGEEEDEDEDLsKyKLDEDE
O95218 S165 Sugiyama ZRANB2 ZIS ZNF265 LKEVEDKEsEGEEEDEDEDLsKyKLDEDEDEDDADLsKyNL
O95218 S181 Sugiyama ZRANB2 ZIS ZNF265 DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR
O95747 S347 Sugiyama OXSR1 KIAA1101 OSR1 RLHKtEDGGWEWsDDEFDEEsEEGKAAIsQLRsPRVKESIS
O95757 S508 Sugiyama HSPA4L APG1 HSPH3 OSP94 GIFSVASASVIEKQNLEGDHsDAPMETEtsFKNENKDNMDK
O95831 S116 Sugiyama AIFM1 AIF PDCD8 NERIsGLGLtPEQKQKKAALsAsEGEEVPQDKAPSHVPFLL
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00491 S176 Sugiyama PNP NP GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA
P00558 S115 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 FLKDCVGPEVEKACANPAAGsVILLENLRFHVEEEGKGKDA
P00558 S415 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GGGAsLELLEGKVLPGVDALsNI__________________
P00558 T378 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA
P02786 S10 Sugiyama TFRC ___________MMDQARsAFsNLFGGEPLsytRFsLARQVD
P02786 S7 Sugiyama TFRC ______________MMDQARsAFsNLFGGEPLsytRFsLAR
P02810 S24 SIGNOR PRH1; PRH2 ILLSVALLAFSSAQDLDEDVsQEDVPLVISDGGDsEQFIDE
P04040 T441 Sugiyama CAT HSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEEQRKRLCE
P04075 S17 Sugiyama ALDOA ALDA ____MPyQyPALtPEQKKELsDIAHRIVAPGKGILAADEst
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04083 S189 Sugiyama ANXA1 ANX1 LPC1 tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04637 S20 SIGNOR|PSP TP53 P53 _MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQAM
P04637 S9 PSP TP53 P53 ____________MEEPQsDPsVEPPLsQEtFsDLWKLLPEN
P04637 T18 SIGNOR|ELM|iPTMNet|PSP TP53 P53 ___MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQ
P04792 S86 Sugiyama HSPB1 HSP27 HSP28 PAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNHFAP
P05023 S217 Sugiyama ATP1A1 DRIPADLRIIsANGCKVDNssLtGESEPQtRsPDFtNENPL
P05187 S114 Sugiyama ALPP PLAP DRFPYVALSKTYNVDKHVPDsGAtATAYLCGVKGNFQTIGL
P05187 S434 Sugiyama ALPP PLAP LYGNGPGYVLKDGARPDVtEsEsGsPEyRQQSAVPLDEETH
P05187 T117 Sugiyama ALPP PLAP PYVALSKTYNVDKHVPDsGAtATAYLCGVKGNFQTIGLSAA
P05187 T185 Sugiyama ALPP PLAP VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC
P05198 T284 Sugiyama EIF2S1 EIF2A EKRGVFNVQMEPKVVtDtDEtELARQMERLERENAEVDGDD
P05386 S101 Sugiyama RPLP1 RRP1 APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S102 Sugiyama RPLP2 D11S2243E RPP2 PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05388 S304 Sugiyama RPLP0 AttAAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD_______
P05388 S307 Sugiyama RPLP0 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05556 S509 Sugiyama ITGB1 FNRB MDF2 MSK12 CRCNEGRVGRHCECstDEVNsEDMDAYCRKENSSEICSNNG
P05787 S280 Sugiyama KRT8 CYK8 IAEVKAQyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDL
P06733 S40 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T18 Sugiyama LDHB ___MATLKEKLIAPVAEEEAtVPNNKITVVGVGQVGMACAI
P07195 T302 Sugiyama LDHB YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD
P07237 S427 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB WDKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFP
P07237 S449 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB ANEVEAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKF
P07237 S88 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNG
P07237 T453 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB EAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKFLESG
P07237 T85 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB KAAGKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFF
P07355 S127 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D AQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEINRVy
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07355 T123 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D LKtPAQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEI
P07355 T31 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D LsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAIKTKGV
P07355 Y188 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT
P07355 Y30 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D KLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAIKTKG
P07737 S30 Sugiyama PFN1 NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P07814 S1473 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 CEDWIKKtTARDQDLEPGAPsMGAKSLCIPFKPLCELQPGA
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07900 S263 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EEKEKEEKEsEDKPEIEDVGsDEEEEKKDGDKKKKKKIKEK
P07900 S476 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA RKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKHIyyItG
P07900 S543 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EPIDEyCVQQLKEFEGKtLVsVTKEGLELPEDEEEKKKQEE
P07900 T195 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DTGEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIG
P07900 T305 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IDQEELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLA
P07900 T317 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P07900 T540 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA yMIEPIDEyCVQQLKEFEGKtLVsVTKEGLELPEDEEEKKK
P07900 T624 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA yGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIE
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S470 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEs
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S532 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yMtEPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK
P08238 S535 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
P08238 T190 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
P08238 T309 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 T537 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK
P08238 Y472 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKE
P08758 S135 Sugiyama ANXA5 ANX5 ENX2 PP4 AsRtPEELRAIKQVyEEEyGssLEDDVVGDTSGYYQRMLVV
P08758 S136 Sugiyama ANXA5 ANX5 ENX2 PP4 sRtPEELRAIKQVyEEEyGssLEDDVVGDTSGYYQRMLVVL
P08758 S37 Sugiyama ANXA5 ANX5 ENX2 PP4 ERADAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAF
P08758 T33 Sugiyama ANXA5 ANX5 ENX2 PP4 PGFDERADAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEI
P08758 T40 Sugiyama ANXA5 ANX5 ENX2 PP4 DAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTL
P08865 S75 Sugiyama RPSA LAMBR LAMR1 WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG
P08865 S78 Sugiyama RPSA LAMBR LAMR1 LLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtP
P08865 S79 Sugiyama RPSA LAMBR LAMR1 LLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtPI
P09104 S40 Sugiyama ENO2 VEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGK
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09382 S63 Sugiyama LGALS1 CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09497 S121 Sugiyama CLTB ESIRKWREEQRKRLQELDAAsKVtEQEWREKAKKDLEEWNQ
P09497 T124 Sugiyama CLTB RKWREEQRKRLQELDAAsKVtEQEWREKAKKDLEEWNQRQs
P09651 S158 Sugiyama HNRNPA1 HNRPA1 TDRGsGKKRGFAFVTFDDHDsVDKIVIQKyHtVNGHNCEVR
P09923 T182 Sugiyama ALPI VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC
P09972 S132 Sugiyama ALDOC ALDC GVVPLAGtDGEtttQGLDGLsERCAQYKKDGADFAKWRCVL
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG47 T55 Sugiyama UBB GIPPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRG
P0CG48 T55 Sugiyama UBC GIPPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRG
P10636 S396 SIGNOR MAPT MAPTL MTBT1 TAU ARMVSKSKDGtGSDDKKAKTsTRSsAKtLKNRPCLsPKHPT
P10636 S519 SIGNOR MAPT MAPTL MTBT1 TAU PPsSGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPtPPTRE
P10636 S721 SIGNOR MAPT MAPTL MTBT1 TAU AKTDHGAEIVyKsPVVsGDtsPRHLsNVsstGsIDMVDsPQ
P10636 T522 SIGNOR MAPT MAPTL MTBT1 TAU SGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPtPPTREPKK
P10696 S111 Sugiyama ALPG ALPPL ALPPL2 DRFPYVALSKTYSVDKHVPDsGAtATAYLCGVKGNFQTIGL
P10696 S431 Sugiyama ALPG ALPPL ALPPL2 LYGNGPGYVLKDGARPDVtEsEsGsPEyRQQSAVPLDGETH
P10696 T114 Sugiyama ALPG ALPPL ALPPL2 PYVALSKTYSVDKHVPDsGAtATAYLCGVKGNFQTIGLSAA
P10809 T422 Sugiyama HSPD1 HSP60 AVLKVGGtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGC
P11047 S942 Sugiyama LAMC1 LAMB2 GFYNLQSGQGCERCDCHALGstNGQCDIRTGQCECQPGITG
P11142 S221 Sugiyama HSPA8 HSC70 HSP73 HSPA10 GGGTFDVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHF
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T37 Sugiyama HSPA8 HSC70 HSP73 HSPA10 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11586 T128 Sugiyama MTHFD1 MTHFC MTHFD SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt
P12277 S163 Sugiyama CKB CKBB PPHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAE
P12830 S844 SIGNOR|ELM|PSP CDH1 CDHE UVO APPYDSLLVFDYEGsGsEAAsLSsLNssEsDKDQDYDYLNE
P13637 S207 Sugiyama ATP1A3 DRVPADLRIISAHGCKVDNssLtGESEPQTRSPDCTHDNPL
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13667 S126 Sugiyama PDIA4 ERP70 ERP72 NILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKILKKG
P13667 S154 Sugiyama PDIA4 ERP70 ERP72 VsGyPtIKILKKGQAVDyEGsRtQEEIVAKVREVSQPDWTP
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13667 S468 Sugiyama PDIA4 ERP70 ERP72 ytFAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAM
P13667 S470 Sugiyama PDIA4 ERP70 ERP72 FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP
P13797 S120 Sugiyama PLS3 KEGICALGGTsELssEGtQHsysEEEKyAFVNWINKALEND
P13797 S339 Sugiyama PLS3 PRIDINMsGFNETDDLKRAEsMLQQADKLGCRQFVTPADVV
P13797 T117 Sugiyama PLS3 INRKEGICALGGTsELssEGtQHsysEEEKyAFVNWINKAL
P13804 S192 Sugiyama ETFA sFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPEL
P13861 S80 Sugiyama PRKAR2A PKR2 PRKAR2 GHPPPEPGPDRVADAKGDsEsEEDEDLEVPVPsRFNRRVsV
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13861 T104 Sugiyama PRKAR2A PKR2 PRKAR2 EDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVIHPKTD
P13861 Y105 Sugiyama PRKAR2A PKR2 PRKAR2 DLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVIHPKTDE
P13929 S40 Sugiyama ENO3 VEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGK
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S100 Sugiyama PKM OIP3 PK2 PK3 PKM2 tHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGPEIR
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 S97 Sugiyama PKM OIP3 PK2 PK3 PKM2 sHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGP
P14618 Y105 Sugiyama PKM OIP3 PK2 PK3 PKM2 AEtIKNVRtAtEsFAsDPILyRPVAVALDTKGPEIRtGLIK
P14625 S172 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 VGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSELI
P14625 S523 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 RtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAG
P14649 S87 Sugiyama MYL6B MLC1SA EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK
P15531 S120 Sugiyama NME1 NDPKA NM23 KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P15531 S122 Sugiyama NME1 NDPKA NM23 GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P15531 S125 Sugiyama NME1 NDPKA NM23 RGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDyTsC
P16070 S71 Sugiyama CD44 LHR MDU2 MDU3 MIC4 DLCKAFNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRI
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P17302 S325 SIGNOR|iPTMNet GJA1 GJAL AsEQNWANysAEQNRMGQAGstIsNsHAQPFDFPDDNQNsK
P17302 S328 SIGNOR|iPTMNet GJA1 GJAL QNWANysAEQNRMGQAGstIsNsHAQPFDFPDDNQNsKKLA
P17302 S330 SIGNOR|iPTMNet GJA1 GJAL WANysAEQNRMGQAGstIsNsHAQPFDFPDDNQNsKKLAAG
P17987 S544 Sugiyama TCP1 CCT1 CCTA ILRIDDLIKLHPESKDDKHGsyEDAVHsGALND________
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18084 S507 Sugiyama ITGB5 CECSPGYLGTRCECQDGENQsVyQNLCREAEGKPLCSGRGD
P18669 S14 Sugiyama PGAM1 PGAMA CDABP0006 _______MAAYKLVLIRHGEsAWNLENRFsGWyDADLsPAG
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P19338 S619 Sugiyama NCL RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK
P19338 T452 Sugiyama NCL AyIEFKTEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQD
P19338 Y462 Sugiyama NCL AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs
P20042 S67 Sugiyama EIF2S2 EIF2B EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK
P20648 S228 Sugiyama ATP4A DRVPADIRILAAQGCKVDNssLtGESEPQTRSPECTHESPL
P20810 S575 Sugiyama CAST APPRDtsQsDKDLDDALDKLsDsLGQRQPDPDENKPMEDKV
P20810 S577 Sugiyama CAST PRDtsQsDKDLDDALDKLsDsLGQRQPDPDENKPMEDKVKE
P21980 T368 Sugiyama TGM2 QPGYEGWQALDPTPQEKsEGtyCCGPVPVRAIKEGDLstKy
P22314 S46 Sugiyama UBA1 A1S9T UBE1 AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA
P22626 S189 Sugiyama HNRNPA2B1 HNRPA2B1 IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF
P22626 S225 Sugiyama HNRNPA2B1 HNRPA2B1 GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P23396 S35 Sugiyama RPS3 OK/SW-cl.26 GIFKAELNEFLtRELAEDGysGVEVRVtPTRTEIIILATRT
P23434 S153 Sugiyama GCSH LVNKSCyEDGWLIKMtLsNPsELDELMsEEAyEKYIKSIEE
P23588 S597 Sugiyama EIF4B KKPEENPASKFssASKyAALsVDGEDENEGEDyAE______
P23921 T774 Sugiyama RRM1 RR1 KEKLKDKEKVSKEEEEKERNtAAMVCsLENRDECLMCGS__
P25054 S1279 ELM APC DP2.5 IQTYCVEDTPICFSRCSSLSsLSSAEDEIGCNQTTQEADSA
P25054 S1392 ELM APC DP2.5 PPEHYVQETPLMFsRCTsVSsLDSFESRSIASSVQSEPCSG
P25054 S1504 PSP APC DP2.5 DADTLLHFATESTPDGFsCsssLsALsLDEPFIQKDVELRI
P25054 S1505 PSP APC DP2.5 ADTLLHFATESTPDGFsCsssLsALsLDEPFIQKDVELRIM
P25054 S1507 PSP APC DP2.5 TLLHFATESTPDGFsCsssLsALsLDEPFIQKDVELRIMPP
P25054 S1510 PSP APC DP2.5 HFATESTPDGFsCsssLsALsLDEPFIQKDVELRIMPPVQE
P25788 S243 Sugiyama PSMA3 HC8 PSC8 GRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM________
P25788 S250 Sugiyama PSMA3 HC8 PSC8 KDIREEAEKyAKEsLKEEDEsDDDNM_______________
P25788 Y239 Sugiyama PSMA3 HC8 PSC8 ELTNGRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM____
P26038 T526 Sugiyama MSN EERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHA
P26641 S304 Sugiyama EEF1G EF1G PRO1608 PKstFVLDEFKRKysNEDtLsVALPyFWEHFDKDGWSLWyS
P26641 T302 Sugiyama EEF1G EF1G PRO1608 HLPKstFVLDEFKRKysNEDtLsVALPyFWEHFDKDGWSLW
P27348 S232 ELM YWHAQ KDstLIMQLLRDNLTLWtsDsAGEECDAAEGAEN_______
P27348 T24 Sugiyama YWHAQ TELIQKAKLAEQAERyDDMAtCMKAVtEQGAELsNEERNLL
P27348 T30 Sugiyama YWHAQ AKLAEQAERyDDMAtCMKAVtEQGAELsNEERNLLsVAyKN
P27695 T19 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 __MPKRGKKGAVAEDGDELRtEPEAKKSKTAAKKNDKEAAG
P27707 S11 PSP DCK __________MAtPPKRsCPsFsAssEGTRIKKISIEGNIA
P27707 S15 PSP DCK ______MAtPPKRsCPsFsAssEGTRIKKISIEGNIAAGKS
P27707 S74 SIGNOR|PSP DCK PVARWCNVQstQDEFEELtMsQKNGGNVLQMMYEKPERWSF
P27707 T72 PSP DCK PEPVARWCNVQstQDEFEELtMsQKNGGNVLQMMYEKPERW
P27797 S189 Sugiyama CALR CRTC THLytLIVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIK
P27797 S193 Sugiyama CALR CRTC tLIVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIKDPDA
P27797 S195 Sugiyama CALR CRTC IVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIKDPDAsK
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P27824 T562 Sugiyama CANX EEGEEKLEEKQKsDAEEDGGtVsQEEEDRKPKAEEDEILNR
P28066 S174 Sugiyama PSMA5 FHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEA
P28066 S179 Sugiyama PSMA5 sGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSL
P29401 S105 Sugiyama TKT VWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGsL
P29401 S295 Sugiyama TKT ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI
P29401 T454 Sugiyama TKT LAMFRsVPtstVFyPsDGVAtEKAVELAANTKGICFIRTsR
P29692 S162 Sugiyama EEF1D EF1D AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 T129 Sugiyama EEF1D EF1D EARLNVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPA
P29692 T147 Sugiyama EEF1D EF1D PQtQHVsPMRQVEPPAKKPAtPAEDDEDDDIDLFGsDNEEE
P30043 S198 Sugiyama BLVRB FLR SCAN KHDLGHFMLRCLttDEyDGHstyPsHQyQ____________
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30085 S180 Sugiyama CMPK1 CMK CMPK UCK UMK UMPK KPIIDLyEEMGKVKKIDASKsVDEVFDEVVQIFDKEG____
P30086 S104 Sugiyama PEBP1 PBP PEBP WHHFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLHRyVWLV
P30101 S155 Sugiyama PDIA3 ERP57 ERP60 GRP58 ASVPLRTEEEFKKFISDKDAsIVGFFDDsFsEAHsEFLKAA
P30101 S163 Sugiyama PDIA3 ERP57 ERP60 GRP58 EEFKKFISDKDAsIVGFFDDsFsEAHsEFLKAASNLRDNYR
P30101 S165 Sugiyama PDIA3 ERP57 ERP60 GRP58 FKKFISDKDAsIVGFFDDsFsEAHsEFLKAASNLRDNYRFA
P30101 S169 Sugiyama PDIA3 ERP57 ERP60 GRP58 ISDKDAsIVGFFDDsFsEAHsEFLKAASNLRDNYRFAHTNV
P30291 S212 SIGNOR|PSP WEE1 KSLLSKARGIDSSSVKLRGssLFMDtEKSGKREFDVRQTPQ
P31153 S38 Sugiyama MAT2A AMS2 MATA2 FLFTSESVGEGHPDKICDQIsDAVLDAHLQQDPDAKVACET
P31327 S1090 Sugiyama CPS1 KNGVKIMGTsPLQIDRAEDRsIFsAVLDELKVAQAPWKAVN
P31327 S1093 Sugiyama CPS1 VKIMGTsPLQIDRAEDRsIFsAVLDELKVAQAPWKAVNTLN
P31327 S1159 Sugiyama CPS1 MNVVFSEDEMKKFLEEAtRVsQEHPVVLTKFVEGAREVEMD
P31327 S863 Sugiyama CPS1 LSEPSsTRIyAIAKAIDDNMsLDEIEKLTYIDKWFLYKMRD
P31327 T1156 Sugiyama CPS1 GSAMNVVFSEDEMKKFLEEAtRVsQEHPVVLTKFVEGAREV
P31943 S281 Sugiyama HNRNPH1 HNRPH HNRPH1 GRDLNyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAt
P31946 T32 Sugiyama YWHAB AKLAEQAERyDDMAAAMKAVtEQGHELsNEERNLLsVAyKN
P31947 S69 Sugiyama SFN HME1 KNVVGGQRAAWRVLSsIEQKsNEEGsEEKGPEVREYREKVE
P31947 S74 Sugiyama SFN HME1 GQRAAWRVLSsIEQKsNEEGsEEKGPEVREYREKVETELQG
P31948 S459 Sugiyama STIP1 EAMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRH
P31948 S460 Sugiyama STIP1 AMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRHD
P32969 S135 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 RNFLGEKYIRRVRMRPGVACsVsQAQKDELILEGNDIELVS
P33993 S314 Sugiyama MCM7 CDC47 MCM2 SETyLEAHRIVKMNKSEDDEsGAGELtREELRQIAEEDFyE
P34897 S417 Sugiyama SHMT2 ERVLELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFR
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931 T39 Sugiyama HSPA1L CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P34932 S415 Sugiyama HSPA4 APG2 HSPH2 TDVVPYPISLRWNsPAEEGssDCEVFSKNHAAPFSKVLTFy
P35222 S45 SIGNOR|ELM|iPTMNet|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 WQQQsyLDsGIHsGATtTAPsLsGKGNPEEEDVDTsQVLyE
P35579 S169 Sugiyama MYH9 HIyAITDtAyRSMMQDREDQsILCTGESGAGKTENTKKVIQ
P35580 S1013 Sugiyama MYH10 QNSKFIKEKKLMEDRIAECssQLAEEEEKAKNLAKIRNKQE
P35637 S163 PSP FUS TLS YGQQQSYNPPQGYGQQNQYNssSGGGGGGGGGGNYGQDQss
P35637 S164 PSP FUS TLS GQQQSYNPPQGYGQQNQYNssSGGGGGGGGGGNYGQDQssM
P35637 S182 PSP FUS TLS NssSGGGGGGGGGGNYGQDQssMSSGGGSGGGYGNQDQSGG
P35637 S183 PSP FUS TLS ssSGGGGGGGGGGNYGQDQssMSSGGGSGGGYGNQDQSGGG
P35637 S221 PSP FUS TLS GGGGSGGYGQQDRGGRGRGGsGGGGGGGGGGYNRSSGGYEP
P35637 S273 PSP FUS TLS GMGGsDRGGFNKFGGPRDQGsRHDsEQDNsDNNtIFVQGLG
P35637 S277 PSP FUS TLS sDRGGFNKFGGPRDQGsRHDsEQDNsDNNtIFVQGLGENVT
P35637 S346 PSP FUS TLS TDRETGKLKGEAtVsFDDPPsAKAAIDWFDGKEFsGNPIKV
P35637 S462 PSP FUS TLS NECNQCKAPKPDGPGGGPGGsHMGGNyGDDRRGGRGGYDRG
P35637 T338 PSP FUS TLS GQPMINLyTDRETGKLKGEAtVsFDDPPsAKAAIDWFDGKE
P35659 S227 Sugiyama DEK ERNsSGMARKAKRTKCPEILsDEsssDEDEKKNKEEssDDE
P36551 S112 Sugiyama CPOX CPO CPX AFGHVQRAEMLPKTSGTRAtsLGRPEEEEDELAHRCSSFMA
P36551 T111 Sugiyama CPOX CPO CPX AAFGHVQRAEMLPKTSGTRAtsLGRPEEEEDELAHRCSSFM
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802 S185 Sugiyama TAGLN2 KIAA0120 CDABP0035 NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37840 S129 iPTMNet SNCA NACP PARK1 QEGILEDMPVDPDNEAyEMPsEEGyQDyEPEA_________
P38646 S212 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P40227 T147 Sugiyama CCT6A CCT6 CCTZ KEKALQFLEEVKVSREMDREtLIDVARTSLRTKVHAELADV
P40925 S326 Sugiyama MDH1 MDHA NDFSREKMDLTAKELtEEKEsAFEFLssA____________
P40925 S332 Sugiyama MDH1 MDHA KMDLTAKELtEEKEsAFEFLssA__________________
P43034 S152 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM
P43243 S234 Sugiyama MATR3 KIAA0723 yDRMDyEDDRLRDGERCRDDsFFGEtsHNyHKFDsEyERMG
P43487 S188 Sugiyama RANBP1 KAGSGKNDHAEKVAEKLEALsVKEETKEDAEEKQ_______
P43629 S385 SIGNOR|PSP KIR3DL1 CD158E NKAT3 NKB1 SNKKNAAVMDQEPAGNRTANsEDsDEQDPEEVTYAQLDHCV
P43629 S388 SIGNOR|PSP KIR3DL1 CD158E NKAT3 NKB1 KNAAVMDQEPAGNRTANsEDsDEQDPEEVTYAQLDHCVFTQ
P45973 S13 Sugiyama CBX5 HP1A ________MGKKTKRtADssssEDEEEyVVEKVLDRRVVKG
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46783 T148 Sugiyama RPS10 RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P46937 S400 SIGNOR YAP1 YAP65 NssDPFLNsGtyHsRDEstDsGLsMssysVPRtPDDFLNsV
P46937 S403 SIGNOR YAP1 YAP65 DPFLNsGtyHsRDEstDsGLsMssysVPRtPDDFLNsVDEM
P47712 S454 Sugiyama PLA2G4A CPLA2 PLA2G4 ssDsDDEsHEPKGtENEDAGsDyQsDNQASWIHRMIMALVS
P47756 S204 Sugiyama CAPZB sGtMNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKI
P47756 S207 Sugiyama CAPZB MNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKIRst
P47756 T202 Sugiyama CAPZB SGsGtMNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMEN
P48730 S181 Sugiyama CSNK1D HCKID tHQHIPYRENKNLtGtARYAsINtHLGIEQsRRDDLESLGY
P48730 T184 Sugiyama CSNK1D HCKID HIPYRENKNLtGtARYAsINtHLGIEQsRRDDLESLGYVLM
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P49327 S2198 Sugiyama FASN FAS EVRQLTLRKLQELSSKADEAsELACPtPKEDGLAQQQtQLN
P49368 S252 Sugiyama CCT3 CCTG TRIC5 YIKNPRIVLLDssLEyKKGEsQtDIEITREEDFTRILQMEE
P49368 T254 Sugiyama CCT3 CCTG TRIC5 KNPRIVLLDssLEyKKGEsQtDIEITREEDFTRILQMEEEY
P49588 S188 Sugiyama AARS1 AARS PGNMKDNFWEMGDtGPCGPCsEIHyDRIGGRDAAHLVNQDD
P49674 S181 Sugiyama CSNK1E THQHIPYRENKNLTGTARYAsINtHLGIEQSRRDDLESLGY
P49674 S323 ELM CSNK1E DVDRERREHEREERMGQLRGsAtRALPPGPPtGAtANRLRs
P49674 S368 ELM CSNK1E VASTPAsRIQPAGNtsPRAIsRVDRERKVSMRLHRGAPANV
P49674 S405 ELM CSNK1E PANVsssDLTGRQEVSRIPAsQtsVPFDHLGK_________
P49674 S408 ELM CSNK1E VsssDLTGRQEVSRIPAsQtsVPFDHLGK____________
P49674 T184 Sugiyama CSNK1E HIPYRENKNLTGTARYAsINtHLGIEQSRRDDLESLGYVLM
P49674 T325 ELM CSNK1E DRERREHEREERMGQLRGsAtRALPPGPPtGAtANRLRsAA
P49674 T334 ELM CSNK1E EERMGQLRGsAtRALPPGPPtGAtANRLRsAAEPVASTPAs
P49674 T337 ELM CSNK1E MGQLRGsAtRALPPGPPtGAtANRLRsAAEPVASTPAsRIQ
P49674 T407 ELM CSNK1E NVsssDLTGRQEVSRIPAsQtsVPFDHLGK___________
P49810 S19 SIGNOR|ELM|iPTMNet PSEN2 AD4 PS2 PSNL2 STM2 __MLTFMAsDsEEEVCDERtsLMsAEsPtPRSCQEGRQGPE
P49810 S327 SIGNOR|ELM|iPTMNet|PSP PSEN2 AD4 PS2 PSNL2 STM2 LDPSSQGALQLPYDPEMEEDsYDsFGEPsYPEVFEPPLTGY
P49810 S330 SIGNOR|ELM|iPTMNet|PSP PSEN2 AD4 PS2 PSNL2 STM2 SSQGALQLPYDPEMEEDsYDsFGEPsYPEVFEPPLTGYPGE
P49810 S335 SIGNOR|iPTMNet PSEN2 AD4 PS2 PSNL2 STM2 LQLPYDPEMEEDsYDsFGEPsYPEVFEPPLTGYPGEELEEE
P49810 S7 SIGNOR|ELM|iPTMNet PSEN2 AD4 PS2 PSNL2 STM2 ______________MLTFMAsDsEEEVCDERtsLMsAEsPt
P49810 S9 SIGNOR|ELM|iPTMNet PSEN2 AD4 PS2 PSNL2 STM2 ____________MLTFMAsDsEEEVCDERtsLMsAEsPtPR
P50395 S427 Sugiyama GDI2 RABGDIB ttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED__
P50395 T425 Sugiyama GDI2 RABGDIB DAttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED
P50416 S371 Sugiyama CPT1A CPT1 GRLLKPREMEQQMQRILDNtsEPQPGEARLAALTAGDRVPW
P50502 S76 Sugiyama ST13 AAG2 FAM10A1 HIP SNC6 KEEKPDSKKVEEDLKADEPssEEsDLEIDKEGVIEPDTDAP
P50502 S79 Sugiyama ST13 AAG2 FAM10A1 HIP SNC6 KPDSKKVEEDLKADEPssEEsDLEIDKEGVIEPDTDAPQEM
P50993 S215 Sugiyama ATP1A2 KIAA0778 DRVPADLRIISSHGCKVDNssLtGESEPQTRSPEFTHENPL
P51116 S601 Sugiyama FXR2 FMR1L2 RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ
P51532 S31 SIGNOR|PSP SMARCA4 BAF190A BRG1 SNF2B SNF2L4 tPRPGPSPGPGPSPGAMLGPsPGPsPGSAHSMMGPSPGPPS
P51532 S35 SIGNOR|PSP SMARCA4 BAF190A BRG1 SNF2B SNF2L4 GPSPGPGPSPGAMLGPsPGPsPGSAHSMMGPSPGPPSAGHP
P51532 S699 Sugiyama SMARCA4 BAF190A BRG1 SNF2B SNF2L4 PPTLPVEEKKKIPDPDsDDVsEVDARHIIENAKQDVDDEyG
P52597 S107 Sugiyama HNRNPF HNRPF KSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPFGCTKEEI
P52597 S63 Sugiyama HNRNPF HNRPF VHFIYTREGRQsGEAFVELGsEDDVKMALKKDRESMGHRyI
P53041 T362 SIGNOR|PSP PPP5C PPP5 QCINGKVLIMHGGLFSEDGVtLDDIRKIERNRQPPDSGPMC
P53618 S474 Sugiyama COPB1 COPB MSTP026 IYRGALWILGEYCSTKEDIQsVMtEIRRSLGEIPIVESEIK
P53618 T477 Sugiyama COPB1 COPB MSTP026 GALWILGEYCSTKEDIQsVMtEIRRSLGEIPIVESEIKKEA
P53985 T231 Sugiyama SLC16A1 MCT1 KAsLEKAGKSGVKKDLHDANtDLIGRHPKQEKRSVFQTINQ
P53999 S19 Sugiyama SUB1 PC4 RPO2TC1 __MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPVKK
P54278 S547 Sugiyama PMS2 PMSL2 RGSQEHVDsQEKAPKTDDSFsDVDCHSNQEDTGCKFRVLPQ
P54577 S386 Sugiyama YARS1 YARS sRLDIRVGKIITVEKHPDADsLyVEKIDVGEAEPRTVVSGL
P54578 S492 Sugiyama USP14 TGT WHIAYVLLYGPRRVEIMEEEsEQ__________________
P54652 S224 Sugiyama HSPA2 GGGTFDVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHL
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T38 Sugiyama HSPA2 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55060 S366 Sugiyama CSE1L CAS XPO2 KVIVPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAA
P55072 S37 Sugiyama VCP HEL-220 HEL-S-70 LKQKNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTV
P55072 S40 Sugiyama VCP HEL-220 HEL-S-70 KNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTVLLK
P55854 S27 Sugiyama SUMO3 SMT3A SMT3H1 KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P55884 S185 Sugiyama EIF3B EIF3S9 EEELLGDVLKDRPQEADGIDsVIVVDNVPQVGPDRLEKLKN
P55957 S64 ELM BID LPVLAPQWEGyDELQtDGNRssHsRLGRIEADsEsQEDIIR
P55957 T59 ELM BID ALGHELPVLAPQWEGyDELQtDGNRssHsRLGRIEADsEsQ
P56817 S498 SIGNOR|ELM|PSP BACE1 BACE KIAA1149 CQWRCLRCLRQQHDDFADDIsLLK_________________
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60660 S30 Sugiyama MYL6 AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60709 S239 Sugiyama ACTB VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61247 S237 Sugiyama RPS3A FTE1 MFTL MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE
P61313 S100 Sugiyama RPL15 EC45 TCBAP0781 tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW
P61604 S21 Sugiyama HSPE1 MAGQAFRKFLPLFDRVLVERsAAETVTKGGIMLPEKSQGKV
P61916 S29 Sugiyama NPC2 HE1 LLLALSTAAQAEPVQFKDCGsVDGVIKEVNVsPCPtQPCQL
P61956 S28 Sugiyama SUMO2 SMT3B SMT3H2 EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P61981 T31 Sugiyama YWHAG ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S156 Sugiyama YWHAE AtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLGLALN
P62258 S210 Sugiyama YWHAE RACRLAKAAFDDAIAELDtLsEEsyKDstLIMQLLRDNLtL
P62258 T161 Sugiyama YWHAE RKEAAENsLVAyKAAsDIAMtELPPTHPIRLGLALNFSVFY
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62495 S295 Sugiyama ETF1 ERF1 RF1 SUP45L1 LSNVKFIQEKKLIGRyFDEIsQDtGKyCFGVEDTLKALEMG
P62736 S241 Sugiyama ACTA2 ACTSA ACTVS GIG46 VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62829 S115 Sugiyama RPL23 FLYFEDNAGVIVNNKGEMKGsAItGPVAKECADLWPRIASN
P62829 T118 Sugiyama RPL23 FEDNAGVIVNNKGEMKGsAItGPVAKECADLWPRIASNAGs
P62857 S61 Sugiyama RPS28 sIIRNVKGPVREGDVLtLLEsEREARRLR____________
P62857 T57 Sugiyama RPS28 DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________
P62917 S138 Sugiyama RPL8 EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62979 T55 Sugiyama RPS27A UBA80 UBCEP1 GIPPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRG
P62987 T55 Sugiyama UBA52 UBCEP2 GIPPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRG
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 T30 Sugiyama YWHAZ AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN
P63151 S409 Sugiyama PPP2R2A RTVLKPRKVCASGKRKKDEIsVDsLDFNKKILHTAWHPKEN
P63151 S412 Sugiyama PPP2R2A LKPRKVCASGKRKKDEIsVDsLDFNKKILHTAWHPKENIIA
P63167 T26 Sugiyama DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF
P63220 S31 Sugiyama RPS21 LYVPRKCSASNRIIGAKDHAsIQMNVAEVDKVTGRFNGQFK
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S239 Sugiyama ACTG1 ACTG VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S240 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 Y72 Sugiyama YBX1 NSEP1 YB1 KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
P67809 Y99 Sugiyama YBX1 NSEP1 YB1 DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P68032 S241 Sugiyama ACTC1 ACTC VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68133 S241 Sugiyama ACTA1 ACTA VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 S439 Sugiyama TUBA1B SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T80 Sugiyama TUBA1B KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68363 Y83 Sugiyama TUBA1B PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P78371 T474 Sugiyama CCT2 99D8.1 CCTB AGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGIT
P78417 S23 Sugiyama GSTO1 GSTTLP28 GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P98082 S193 Sugiyama DAB2 DOC2 KKKEEEKKKIEEASKAVENGsEALMILDDQTNKLKSGVDQM
Q00535 S159 SIGNOR|ELM CDK5 CDKN5 PSSALRE ELKLADFGLARAFGIPVRCYsAEVVTLWYRPPDVLFGAKLY
Q00610 S1494 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 EEDyQALRTsIDAyDNFDNIsLAQRLEKHELIEFRRIAAYL
Q00987 S118 SIGNOR|PSP MDM2 KIYTMIYRNLVVVNQQESSDsGTsVSENRCHLEGGSDQKDL
Q00987 S121 SIGNOR|PSP MDM2 TMIYRNLVVVNQQESSDsGTsVSENRCHLEGGSDQKDLVQE
Q00987 S166 PSP MDM2 KPSSSHLVSRPstSSRRRAIsEtEENsDELsGERQRKRHKs
Q00987 S172 PSP MDM2 LVSRPstSSRRRAIsEtEENsDELsGERQRKRHKsDsISLs
Q00987 S176 PSP MDM2 PstSSRRRAIsEtEENsDELsGERQRKRHKsDsISLsFDES
Q00987 S220 PSP MDM2 CVIREICCERSSSSESTGtPsNPDLDAGVsEHSGDWLDQDs
Q00987 S229 PSP MDM2 RSSSSESTGtPsNPDLDAGVsEHSGDWLDQDsVsDQFsVEF
Q00987 S240 PSP MDM2 sNPDLDAGVsEHSGDWLDQDsVsDQFsVEFEVEsLDsEDYs
Q00987 S246 SIGNOR MDM2 AGVsEHSGDWLDQDsVsDQFsVEFEVEsLDsEDYsLsEEGQ
Q00987 S253 SIGNOR|PSP MDM2 GDWLDQDsVsDQFsVEFEVEsLDsEDYsLsEEGQELsDEDD
Q00987 S260 PSP MDM2 sVsDQFsVEFEVEsLDsEDYsLsEEGQELsDEDDEVyQVtV
Q00987 S262 SIGNOR|PSP MDM2 sDQFsVEFEVEsLDsEDYsLsEEGQELsDEDDEVyQVtVyQ
Q00987 S269 SIGNOR|PSP MDM2 FEVEsLDsEDYsLsEEGQELsDEDDEVyQVtVyQAGESDTD
Q00987 S290 PSP MDM2 DEDDEVyQVtVyQAGESDTDsFEEDPEISLADyWKCTSCNE
Q00987 S342 PSP MDM2 CWALRENWLPEDKGKDKGEIsEKAKLENstQAEEGFDVPDC
Q00987 S350 PSP MDM2 LPEDKGKDKGEIsEKAKLENstQAEEGFDVPDCKKtIVNDS
Q00987 S373 PSP MDM2 AEEGFDVPDCKKtIVNDSREsCVEENDDKITQAsQSQESED
Q00987 S386 PSP MDM2 IVNDSREsCVEENDDKITQAsQSQESEDysQPSTSsSIIyS
Q00987 T279 PSP MDM2 YsLsEEGQELsDEDDEVyQVtVyQAGESDTDsFEEDPEISL
Q00987 T351 PSP MDM2 PEDKGKDKGEIsEKAKLENstQAEEGFDVPDCKKtIVNDSR
Q00987 T365 PSP MDM2 AKLENstQAEEGFDVPDCKKtIVNDSREsCVEENDDKITQA
Q00987 T419 PSP MDM2 TSsSIIySsQEDVKEFEREEtQDKEEsVESsLPLNAIEPCV
Q01105 S168 Sugiyama SET ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01650 S31 Sugiyama SLC7A5 CD98LC LAT1 MPE16 LAAPAAEEKEEAREKMLAAKsADGsAPAGEGEGVtLQRNIT
Q01650 S35 Sugiyama SLC7A5 CD98LC LAT1 MPE16 AAEEKEEAREKMLAAKsADGsAPAGEGEGVtLQRNITLLNG
Q02790 T42 Sugiyama FKBP4 FKBP52 GVDIsPKQDEGVLKVIKREGtGTEMPMIGDRVFVHYTGWLL
Q02880 S1132 SIGNOR TOP2B KEAQEKAAEEDETQNQHDDSsSDsGTPSGPDFNYILNMSLW
Q04637 S1430 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI GQDIGAFVAEQKVEyTLGEEsEAPGQRALPsEELNRQLEKL
Q04726 S622 Sugiyama TLE3 KIAA1547 VWDLHNQTLVRQFQGHTDGAsCIDISHDGTKLWTGGLDNTV
Q04760 S114 Sugiyama GLO1 SRKATLELTHNWGtEDDEtQsyHNGNsDPRGFGHIGIAVPD
Q04760 S120 Sugiyama GLO1 ELTHNWGtEDDEtQsyHNGNsDPRGFGHIGIAVPDVySACK
Q04917 S25 Sugiyama YWHAH YWHA1 EQLLQRARLAEQAERyDDMAsAMKAVtELNEPLsNEDRNLL
Q04917 T31 Sugiyama YWHAH YWHA1 ARLAEQAERyDDMAsAMKAVtELNEPLsNEDRNLLsVAyKN
Q05940 S511 ELM SLC18A2 SVMT VMAT2 KTKMYTQNNIQSYPIGEDEEsEsD_________________
Q05940 S513 ELM SLC18A2 SVMT VMAT2 KMYTQNNIQSYPIGEDEEsEsD___________________
Q07021 S201 Sugiyama C1QBP GC1QBP HABP1 SF2P32 ALVLDCHyPEDEVGQEDEAEsDIFsIREVsFQstGESEWKD
Q07021 S205 Sugiyama C1QBP GC1QBP HABP1 SF2P32 DCHyPEDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYT
Q08211 S125 Sugiyama DHX9 DDX9 LKP NDH2 LPttMGGPLPPHLALKAENNsEVGAsGyGVPGPTWDRGANL
Q12792 T164 Sugiyama TWF1 PTK9 PAPLtAAEEELRQIKINEVQtDVGVDTKHQtLQGVAFPISR
Q12906 S190 Sugiyama ILF3 DRBF MPHOSPH4 NF90 HLTSPVVREEMEKVLAGEtLsVNDPPDVLDRQKCLAALASL
Q12906 S46 Sugiyama ILF3 DRBF MPHOSPH4 NF90 EELEAVQNMVsHtERALKAVsDWIDEQEKGssEQAEsDNMD
Q12959 S733 Sugiyama DLG1 YTRPVIILGPMKDRINDDLIsEFPDKFGSCVPHTTRPKRDY
Q12968 S207 ELM NFATC3 NFAT4 HIYDDVDSELNEAAARFtLGsPLtsPGGsPGGCPGEETWHQ
Q12968 S211 ELM NFATC3 NFAT4 DVDSELNEAAARFtLGsPLtsPGGsPGGCPGEETWHQQYGL
Q12968 S215 ELM NFATC3 NFAT4 ELNEAAARFtLGsPLtsPGGsPGGCPGEETWHQQYGLGHSL
Q12968 T204 ELM NFATC3 NFAT4 sLsHIYDDVDSELNEAAARFtLGsPLtsPGGsPGGCPGEET
Q12968 T210 ELM NFATC3 NFAT4 DDVDSELNEAAARFtLGsPLtsPGGsPGGCPGEETWHQQYG
Q13148 S292 PSP TARDBP TDP43 RsGRFGGNPGGFGNQGGFGNsRGGGAGLGNNQGsNMGGGMN
Q13148 S305 PSP TARDBP TDP43 NQGGFGNsRGGGAGLGNNQGsNMGGGMNFGAFsINPAMMAA
Q13148 S317 PSP TARDBP TDP43 AGLGNNQGsNMGGGMNFGAFsINPAMMAAAQAALQSsWGMM
Q13148 S333 PSP TARDBP TDP43 FGAFsINPAMMAAAQAALQSsWGMMGMLAsQQNQsGPsGNN
Q13148 S389 PSP TARDBP TDP43 sGNNSYsGsNsGAAIGWGsAsNAGsGsGFNGGFGssMDsKs
Q13148 S393 PSP TARDBP TDP43 SYsGsNsGAAIGWGsAsNAGsGsGFNGGFGssMDsKssGWG
Q13148 S395 PSP TARDBP TDP43 sGsNsGAAIGWGsAsNAGsGsGFNGGFGssMDsKssGWGM_
Q13148 S403 PSP TARDBP TDP43 IGWGsAsNAGsGsGFNGGFGssMDsKssGWGM_________
Q13148 S404 PSP TARDBP TDP43 GWGsAsNAGsGsGFNGGFGssMDsKssGWGM__________
Q13148 S409 PSP TARDBP TDP43 sNAGsGsGFNGGFGssMDsKssGWGM_______________
Q13148 S410 PSP TARDBP TDP43 NAGsGsGFNGGFGssMDsKssGWGM________________
Q13148 S92 PSP TARDBP TDP43 VYVVNYPKDNKRKMDEtDAssAVKVKRAVQKTSDLIVLGLP
Q13263 S784 Sugiyama TRIM28 KAP1 RNF96 TIF1B DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK
Q13283 T241 Sugiyama G3BP1 G3BP ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP
Q13428 S341 Sugiyama TCOF1 GKAGAVAsQTKAGKPEEDSEsSSEEssDsEEETPAAKALLQ
Q13547 S85 Sugiyama HDAC1 RPD3L1 TKYHSDDyIKFLRSIRPDNMsEysKQMQRFNVGEDCPVFDG
Q13610 S59 Sugiyama PWP1 AKEKLQEEGGGsDEEEtGsPsEDGMQsARTQARPREPLEDG
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S988 Sugiyama EIF3A EIF3S10 KIAA0139 PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN
Q14152 T1031 Sugiyama EIF3A EIF3S10 KIAA0139 HADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGPRRG
Q14152 T1378 Sugiyama EIF3A EIF3S10 KIAA0139 AEKDREsLRRTKNEtDEDGWttVRR________________
Q14157 S475 Sugiyama UBAP2L KIAA0144 NICE4 PLPsKstsAPQMsPGssDNQsssPQPAQQKLKQQKKKAsLT
Q14203 S417 Sugiyama DCTN1 KKNQELEVVRQQRERLQEELsQAEstIDELKEQVDAALGAE
Q14203 S421 Sugiyama DCTN1 ELEVVRQQRERLQEELsQAEstIDELKEQVDAALGAEEMVE
Q14257 S146 Sugiyama RCN2 ERC55 MyDRVIDFDENtALDDAEEEsFRKLHLKDKKRFEKANQDSG
Q14257 T137 Sugiyama RCN2 ERC55 VTWDEyNIQMyDRVIDFDENtALDDAEEEsFRKLHLKDKKR
Q14444 S97 Sugiyama CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 DYQERMNKGERLNQDQLDAVsKyQEVtNNLEFAKELQRsFM
Q14498 S334 Sugiyama RBM39 HCC1 RNPC2 FELAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtT
Q14498 S337 Sugiyama RBM39 HCC1 RNPC2 AGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGRL
Q14511 S780 PSP NEDD9 CASL GDTLTRQVTAQDIRNKVMNSsNQLCEQLKTIVMATKMAALH
Q14511 T804 PSP NEDD9 CASL CEQLKTIVMATKMAALHYPStTALQEMVHQVTDLSRNAQLF
Q14566 S271 Sugiyama MCM6 VPDVSKLSTPGARAEtNsRVsGVDGyEtEGIRGLRALGVRD
Q14566 S758 Sugiyama MCM6 EDESALKRSELVNWYLKEIEsEIDsEEELINKKRIIEKVIH
Q14566 T266 Sugiyama MCM6 GTLIVVPDVSKLSTPGARAEtNsRVsGVDGyEtEGIRGLRA
Q14677 S166 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14978 S637 Sugiyama NOLC1 KIAA0035 NS5ATP13 GEKRAssPFRRVREEEIEVDsRVADNsFDAKRGAAGDWGER
Q15056 S13 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 ________MADFDtyDDRAyssFGGGRGsRGsAGGHGsRSQ
Q15084 S428 Sugiyama PDIA6 ERP5 P5 TXNDC7 EREPWDGRDGELPVEDDIDLsDVELDDLGKDEL________
Q15181 S127 Sugiyama PPA1 IOPPP PP NDKHTGCCGDNDPIDVCEIGsKVCARGEIIGVKVLGILAMI
Q15185 S72 Sugiyama PTGES3 P23 TEBP EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE
Q15293 S315 Sugiyama RCN1 RCN NKDEKLTKEEILENWNMFVGsQAtNyGEDLtKNHDEL____
Q15293 T318 Sugiyama RCN1 RCN EKLTKEEILENWNMFVGsQAtNyGEDLtKNHDEL_______
Q15293 T71 Sugiyama RCN1 RCN EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI
Q15642 S504 Sugiyama TRIP10 CIP4 STOT STP SRHARPPDPPAsAPPDsssNsAsQDtKESSEEPPSEESQDT
Q15700 S699 Sugiyama DLG2 YTRPVIILGPMKDRINDDLIsEFPDKFGSCVPHTTRPKRDY
Q15758 S535 Sugiyama SLC1A5 ASCT2 M7V1 RDR RDRC EEGNPLLKHyRGPAGDAtVAsEKEsVM______________
Q15758 S539 Sugiyama SLC1A5 ASCT2 M7V1 RDR RDRC PLLKHyRGPAGDAtVAsEKEsVM__________________
Q15758 T532 Sugiyama SLC1A5 ASCT2 M7V1 RDR RDRC VPTEEGNPLLKHyRGPAGDAtVAsEKEsVM___________
Q16643 S255 Sugiyama DBN1 D0S117E HRRKQQTLEAEEAKRRLKEQsIFGDHRDEEEEtHMKKsEsE
Q16665 S247 SIGNOR|PSP HIF1A BHLHE78 MOP1 PASD8 IPHPSNIEIPLDSKTFLSRHsLDMKFSYCDERITELMGYEP
Q16822 T109 Sugiyama PCK2 PEPCK2 yNNCWLARTDPKDVARVESKtVIVTPSQRDTVPLPPGGARG
Q32P51 S158 Sugiyama HNRNPA1L2 HNRNPA1L TDRGsGKKRGFAFVTFDDHDsVDKIVIQKYHTVKGHNCEVR
Q4G0J3 S261 Sugiyama LARP7 HDCMA18P MDtsNtsIsKMKRsRPtsEGsDIEstEPQKQCSKKKKKRDR
Q562R1 S240 Sugiyama ACTBL2 VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE
Q58FF6 T165 Sugiyama HSP90AB4P DHGEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIG
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S405 Sugiyama HSP90AB3P HSP90BC YMTEPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK
Q58FF7 S408 Sugiyama HSP90AB3P HSP90BC EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
Q58FF7 T169 Sugiyama HSP90AB3P HSP90BC DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
Q58FF7 T410 Sugiyama HSP90AB3P HSP90BC IDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK
Q58FF8 S305 Sugiyama HSP90AB2P HSP90BB RVVYMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKR
Q58FF8 S308 Sugiyama HSP90AB2P HSP90BB YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE
Q58FG1 S251 Sugiyama HSP90AA4P HSP90AD HSPCAL2 EPIDEYCVQQLKEFEGKtLVsVTKEDLELPEDEEEKKKQEE
Q58FG1 T248 Sugiyama HSP90AA4P HSP90AD HSPCAL2 YTIEPIDEYCVQQLKEFEGKtLVsVTKEDLELPEDEEEKKK
Q5H9R7 S617 Sugiyama PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 NIALFEACCKERIQQFDDGGsDEEDIWEEKHIAFtPEsQRR
Q5JTH9 S66 Sugiyama RRP12 KIAA0690 SGRSDLTVDAVKLHNELQsGsLRLGKsEAPEtPMEEEAELV
Q66LE6 S415 Sugiyama PPP2R2D KIAA1541 RASLKPRKVCTGGKRRKDEIsVDsLDFNKKILHTAWHPVDN
Q66LE6 S418 Sugiyama PPP2R2D KIAA1541 LKPRKVCTGGKRRKDEIsVDsLDFNKKILHTAWHPVDNVIA
Q68BL8 T505 Sugiyama OLFML2B DDIRNVIGRCKDTLSTITGPttQNtyGRNEGAWMKDPLAKD
Q68BL8 T506 Sugiyama OLFML2B DIRNVIGRCKDTLSTITGPttQNtyGRNEGAWMKDPLAKDE
Q68BL8 T509 Sugiyama OLFML2B NVIGRCKDTLSTITGPttQNtyGRNEGAWMKDPLAKDERIY
Q68BL8 Y510 Sugiyama OLFML2B VIGRCKDTLSTITGPttQNtyGRNEGAWMKDPLAKDERIYV
Q68D20 S161 Sugiyama PMS2CL PMS2P13 RGSQEHVDsQEKAPEtDDsFsDVDCHSNQEDTGCKFQVLPQ
Q6EEV6 S28 Sugiyama SUMO4 SMT3H4 EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC
Q6NZY4 T346 Sugiyama ZCCHC8 AELENsGLALYDGKDGtDGEtEVGEIQQNKSVTYDLSKLVN
Q6P996 S779 Sugiyama PDXDC1 KIAA0251 QHtDQtEAFQKGVPHPEDDHsQVEGPEsLR___________
Q6PCE3 S311 Sugiyama PGM2L1 BM32A QKDPDPDFSTVKCPNPEEGEsVLELsLRLAEKENARVVLAT
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 S939 Sugiyama POTEE A26C1A POTE2 VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
Q6U7Q0 S396 SIGNOR|PSP ZNF322 ZNF322A ZNF388 ZNF489 EKPFVCNVSEKGLELsPPHAsEAsQMS______________
Q6ULP2 S508 Sugiyama AFTPH AFTH SCQEETILTKSDLKQTSDNLsEECQLARKSSGTGTEPVAKL
Q6UN15 S87 Sugiyama FIP1L1 FIP1 RHE EtAENGVPKPKVTETEDDsDsDsDDDEDDVHVTIGDIKTGA
Q6UXH1 S295 Sugiyama CRELD2 UNQ185/PRO211 KECISGYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSY
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q71U36 S439 Sugiyama TUBA1A TUBA3 SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T80 Sugiyama TUBA1A TUBA3 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71U36 Y83 Sugiyama TUBA1A TUBA3 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q7KZ85 S73 Sugiyama SUPT6H KIAA0162 SPT6H NLKGFINDDDDEDEGEEDEGsDSGDsEDDVGHKKRKRtsFD
Q7KZ85 S78 Sugiyama SUPT6H KIAA0162 SPT6H INDDDDEDEGEEDEGsDSGDsEDDVGHKKRKRtsFDDRLED
Q7KZF4 S473 Sugiyama SND1 TDRD11 ALVSKGLATVIRYRQDDDQRssHyDELLAAEARAIKNGKGL
Q7Z460 S1216 Sugiyama CLASP1 KIAA0622 MAST1 sQEDLNEPIKRDGKKECDIVsRDGGAAsPAtEGRGGsEVEG
Q7Z460 S246 Sugiyama CLASP1 KIAA0622 MAST1 VQKSGNMIQSANDKNFDDEDsVDGNRPssAsStSSKAPPSS
Q8IWX8 S823 Sugiyama CHERP DAN26 SCAF6 KSYSPGRRRRsRsRsPtPPssAGLGsNsAPPIPDSRLGEEN
Q8N392 S209 Sugiyama ARHGAP18 TEsQSLRTNENKYQGRDDEAsNLVGEEKLIPPEETPAPETD
Q8N6T3 S270 Sugiyama ARFGAP1 ARF1GAP NVLKPAQEKVKEGKIFDDVSsGVsQLAsKVQGVGSKGWRDV
Q8N6T3 S273 Sugiyama ARFGAP1 ARF1GAP KPAQEKVKEGKIFDDVSsGVsQLAsKVQGVGSKGWRDVttF
Q8N6T3 S348 Sugiyama ARFGAP1 ARF1GAP FWETFGSAEPTKtRKsPssDsWtCADtstERRssDsWEVWG
Q8N6T3 T350 Sugiyama ARFGAP1 ARF1GAP ETFGSAEPTKtRKsPssDsWtCADtstERRssDsWEVWGSA
Q8NBJ7 S283 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 GsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPPGEL__
Q8NBS9 S125 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 KYNSMEDAKVYVAKVDCtAHsDVCsAQGVRGYPTLKLFKPG
Q8NBS9 S129 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 MEDAKVYVAKVDCtAHsDVCsAQGVRGYPTLKLFKPGQEAV
Q8NHW5 S304 Sugiyama RPLP0P6 DTTAAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD_______
Q8NHW5 S307 Sugiyama RPLP0P6 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
Q8TF05 S57 Sugiyama PPP4R1 MEG1 PP4R1 DFVSQDEMLTPLGRLDKyAAsENIFNRQMVARSLLDTLREV
Q8WU90 S231 Sugiyama ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 LPPGFVLKKDKKKEEKEDEIsLEDLIERERSALGPNVTKIT
Q8WU90 S351 Sugiyama ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 DIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLsEAs
Q8WU90 S360 Sugiyama ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 RDVDEtGItVAsLERFSTYTsDKDENKLsEAsGGRAENGER
Q8WU90 T345 Sugiyama ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 DsVsVNDIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDEN
Q8WU90 T348 Sugiyama ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 sVNDIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLs
Q8WWI1 S709 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 VERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEMQKIKS
Q92598 S852 Sugiyama HSPH1 HSP105 HSP110 KIAA0201 NNFGAEPPHQNGECyPNEKNsVNMDLD______________
Q92620 S438 Sugiyama DHX38 DDX38 KIAA0224 PRP16 DGRIVFTKQPEPVIPVKDATsDLAIIARKGSQTVRKHREQK
Q92769 S422 Sugiyama HDAC2 PDKRIsIRAsDKRIACDEEFsDsEDEGEGGRRNVADHKKGA
Q92769 S424 Sugiyama HDAC2 KRIsIRAsDKRIACDEEFsDsEDEGEGGRRNVADHKKGAKK
Q92769 S86 Sugiyama HDAC2 TKYHSDEYIKFLRSIRPDNMsEysKQMQRFNVGEDCPVFDG
Q92973 S339 Sugiyama TNPO1 KPNB2 MIP1 TRN SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE
Q92973 T335 Sugiyama TNPO1 KPNB2 MIP1 TRN GMKySDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQ
Q93062 S14 Sugiyama RBPMS HERMES _______MNNGGKAEKENtPsEANLQEEEVRTLFVSGLPLD
Q96CT7 S122 Sugiyama CCDC124 DtLRRDHQLREAPDTAEKAKsHLEVPLEENVNRRVLEEGsV
Q96FS4 S55 Sugiyama SIPA1 SPA1 PLTPHTFEPRPVRGPLLRsGsDAGEARPPtPAsPRARAHsH
Q96G46 T57 Sugiyama DUS3L TKEQFHQFLEAKGQEKtCREtEVGDPAGNELAEPEAKRIRL
Q96GM8 S420 Sugiyama TOE1 KNDLEMGIKAARPEIADRATsEVPGsQAsPNPVPGDGLHRA
Q96HE7 S143 Sugiyama ERO1A ERO1L UNQ434/PRO865 EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD
Q96HE7 S145 Sugiyama ERO1A ERO1L UNQ434/PRO865 NNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNF
Q96HE7 T148 Sugiyama ERO1A ERO1L UNQ434/PRO865 IEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNFCEA
Q96KB5 S298 Sugiyama PBK TOPK RPPINMEELDESYQKVIELFsVCtNEDPKDRPsAAHIVEAL
Q96KB5 T301 Sugiyama PBK TOPK INMEELDESYQKVIELFsVCtNEDPKDRPsAAHIVEALEtD
Q96RE7 S175 Sugiyama NACC1 BTBD14B NAC1 ACSTPLPLVSRVKTEQQESDsVQCMPVAKRLWDsGQKEAGG
Q96S66 S59 Sugiyama CLCC1 KIAA0761 MCLC MRKSQAKYGISGEKDVSPDLsCADEIsECyHKLDSLTYKID
Q96S66 Y68 Sugiyama CLCC1 KIAA0761 MCLC ISGEKDVSPDLsCADEIsECyHKLDSLTYKIDECEKKKRED
Q96SB4 S334 Sugiyama SRPK1 ERPLKENPPNKMtQEKLEEsstIGQDQtLMERDTEGGAAEI
Q96T88 S95 SIGNOR|PSP UHRF1 ICBP90 NP95 RNF106 QsLVLPHSTKERDsELsDtDsGCCLGQSESDKsstHGEAAA
Q99439 S217 Sugiyama CNN2 ILPPMDHSTISLQMGTNKCAsQVGMTAPGTRRHIyDTKLGT
Q99497 S57 Sugiyama PARK7 GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL
Q99613 S15 Sugiyama EIF3C EIF3S8 ______MSRFFttGsDsEsEssLsGEELVTKPVGGNyGKQP
Q99613 S16 Sugiyama EIF3C EIF3S8 _____MSRFFttGsDsEsEssLsGEELVTKPVGGNyGKQPL
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99733 S121 Sugiyama NAP1L4 NAP2 PLFDKRREFItGDVEPtDAEsEWHsENEEEEKLAGDMKSKV
Q99733 S125 Sugiyama NAP1L4 NAP2 KRREFItGDVEPtDAEsEWHsENEEEEKLAGDMKSKVVVTE
Q99814 S383 PSP EPAS1 BHLHE73 HIF2A MOP2 PASD2 FKPHLMAMNSIFDSSGKGAVsEKSNFLFTKLKEEPEELAQL
Q99814 T528 PSP EPAS1 BHLHE73 HIF2A MOP2 PASD2 DTEAKDQCSTQTDFNELDLEtLAPYIPMDGEDFQLSPICPE
Q99848 S269 Sugiyama EBNA1BP2 EBP2 GFGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPGKKGS
Q99961 S108 Sugiyama SH3GL1 CNSA1 SH3D2B QSEGLLGECMIRHGKELGGEsNFGDALLDAGEsMKRLAEVK
Q9BQ52 S215 Sugiyama ELAC2 HPC2 QPWQsPERPLsRLsPERssDsEsNENEPHLPHGVsQRRGVR
Q9BQ52 S217 Sugiyama ELAC2 HPC2 WQsPERPLsRLsPERssDsEsNENEPHLPHGVsQRRGVRDs
Q9BQE3 S439 Sugiyama TUBA1C TUBA6 SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T80 Sugiyama TUBA1C TUBA6 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BQE3 Y83 Sugiyama TUBA1C TUBA6 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BQK8 S262 Sugiyama LPIN3 LIPN3L SHMQWAWGRLPKVARAERPEsSVVLEGRAGATSPPRGGPST
Q9BRK4 S220 PSP LZTS2 KIAA1813 LAPSER1 DKPLAFSGWASGCPSGTLSDsGRNsLssLPTYSTGGAEPtt
Q9BRK4 S224 PSP LZTS2 KIAA1813 LAPSER1 AFSGWASGCPSGTLSDsGRNsLssLPTYSTGGAEPttssPG
Q9BRK4 S273 PSP LZTS2 KIAA1813 LAPSER1 GRGALPGPARGVPTGPSHSDsGRssSsKSTGSLGGRVAGGL
Q9BRK4 S277 PSP LZTS2 KIAA1813 LAPSER1 LPGPARGVPTGPSHSDsGRssSsKSTGSLGGRVAGGLLGsG
Q9BWU0 S709 Sugiyama SLC4A1AP HLC3 SRGELKKKKTPGPGKLPPTLsSKYPEDDPDYCVWVPPEGQS
Q9BYX7 S239 Sugiyama POTEKP ACTBL3 FKSG30 VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BZL6 S244 PSP PRKD2 PKD2 HSPC187 RsttELLPRRPPsssssssAssYTGRPIELDKMLLSKVKVP
Q9C0C2 S1174 Sugiyama TNKS1BP1 KIAA1741 TAB182 ttAGsVDWTDQLGLRNLEVssCVGsGGssEAREsAVGQMGW
Q9C0C2 S1331 Sugiyama TNKS1BP1 KIAA1741 TAB182 WGNNLGLRDLEVtCDPDsGGsQGLRGCGVGQMDWTQDLAPQ
Q9GZV5 S314 SIGNOR WWTR1 TAZ NssDPFLNGGPyHsREQsTDsGLGLGCySVPTtPEDFLSNV
Q9H1E3 S144 Sugiyama NUCKS1 NUCKS JC7 PFQEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPER
Q9H1I8 S549 Sugiyama ASCC2 ASC1P100 RQT3 PTPLLTSRHNVFQNDEFDVFsRDsVDLSRVHKGKSTRKEEN
Q9H1I8 S552 Sugiyama ASCC2 ASC1P100 RQT3 LLTSRHNVFQNDEFDVFsRDsVDLSRVHKGKSTRKEENTRS
Q9H2U2 S309 Sugiyama PPA2 HSPC124 NCTNVQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVW
Q9H2U2 S313 Sugiyama PPA2 HSPC124 VQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLG
Q9H2U2 S315 Sugiyama PPA2 HSPC124 ISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK_
Q9H3P7 S393 Sugiyama ACBD3 GCP60 GOCAP1 GOLPH1 SMWTRPQIKDFKEKIQQDADsVItVGRGEVVTVRVPTHEEG
Q9H3P7 T396 Sugiyama ACBD3 GCP60 GOCAP1 GOLPH1 TRPQIKDFKEKIQQDADsVItVGRGEVVTVRVPTHEEGSYL
Q9H6Z4 S355 Sugiyama RANBP3 PKLNEVssDANRENAAAEsGsEsssQEAtPEKESLAEsAAA
Q9H6Z4 S357 Sugiyama RANBP3 LNEVssDANRENAAAEsGsEsssQEAtPEKESLAEsAAAyT
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ39 T159 Sugiyama RPS10P5 RPS10L RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9NR28 S230 Sugiyama DIABLO SMAC EAQIEELRQKTQEEGEERAEsEQEAyLRED___________
Q9NR28 Y235 Sugiyama DIABLO SMAC ELRQKTQEEGEERAEsEQEAyLRED________________
Q9NR30 S466 Sugiyama DDX21 ETKKEAQELSQNsAIKQDAQsLHGDIPQKQREITLKGFRNG
Q9NTJ3 S27 Sugiyama SMC4 CAPC SMC4L1 QPSTARRREEGPPPPsPDGAssDAEPEPPsGRtEsPAtAAE
Q9NUQ3 S86 Sugiyama TXLNG CXorf15 ELRG LSR5 HQGSNCGGTSNKHSLEEDEGsDFItENRNLVsPAyCtQEsR
Q9NW13 S200 Sugiyama RBM28 KGRTVAVDWAVAKDKYKDTQsVsAIGEEKSHESKHQESVKK
Q9NW13 S202 Sugiyama RBM28 RTVAVDWAVAKDKYKDTQsVsAIGEEKSHESKHQESVKKKG
Q9NYL9 S25 Sugiyama TMOD3 FRKDLEKyKDLDEDELLGNLsEtELKQLETVLDDLDPENAL
Q9NZL9 S110 Sugiyama MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 IVHCAAERRPDVVENQPDAAsQLNVDASGNLAKEAAAVGAF
Q9P2I0 S419 Sugiyama CPSF2 CPSF100 KIAA1367 EKLKKEAAKKLEQSKEADIDssDEsDIEEDIDQPSAHKTKH
Q9P2I0 S420 Sugiyama CPSF2 CPSF100 KIAA1367 KLKKEAAKKLEQSKEADIDssDEsDIEEDIDQPSAHKTKHD
Q9P2I0 S423 Sugiyama CPSF2 CPSF100 KIAA1367 KEAAKKLEQSKEADIDssDEsDIEEDIDQPSAHKTKHDLMM
Q9UBU9 S62 Sugiyama NXF1 TAP RGGSGIRSSRLEEDDGDVAMsDAQDGPRVRYNPYTTRPNRR
Q9UHD8 S247 Sugiyama SEPTIN9 KIAA0991 MSF SEPT9 PQPPVAEAtPRsQEATEAAPsCVGDMADtPRDAGLKQAPAS
Q9UI15 S185 Sugiyama TAGLN3 NP25 EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______
Q9Y266 S285 Sugiyama NUDC NtKKINPENsKLsDLDsEtRsMVEKMMYDQRQKsMGLPtsD
Q9Y2B0 S116 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 IDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKFA
Q9Y2T7 Y107 Sugiyama YBX2 CSDA3 MSY2 KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
Q9Y2X7 S385 Sugiyama GIT1 DNLELsLRSQSDLDDQHDyDsVAsDEDtDQEPLRSTGATRS
Q9Y2X7 S388 Sugiyama GIT1 ELsLRSQSDLDDQHDyDsVAsDEDtDQEPLRSTGATRSNRA
Q9Y383 S347 Sugiyama LUC7L2 CGI-59 CGI-74 SRERSKRRSSKERFRDQDLAsCDRDRssRDRSPRDRDRKDK
Q9Y3B8 S203 Sugiyama REXO2 SFN SMFN CGI-114 EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK
Q9Y3B9 S266 Sugiyama RRP15 KIAA0507 CGI-115 WTILRDDFMMGAsMKDWDKEsDGPDDSRPEsAsDsDt____
Q9Y3B9 S67 Sugiyama RRP15 KIAA0507 CGI-115 GSCGsEKDHFYsDDDAIEADsEGDAEPCDKENENDGEssVG
Q9Y450 S64 Sugiyama HBS1L HBS1 KIAA1038 RRDKPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsC
Q9Y4K0 S411 Sugiyama LOXL2 NEIQCTGNEKSIIDCKFNAEsQGCNHEEDAGVRCNTPAMGL
Q9Y5J1 S210 Sugiyama UTP18 WDR50 CDABP0061 CGI-48 MGGVPAWAETTKRKtssDDEsEEDEDDLLQRTGNFISTsTS
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y696 S236 Sugiyama CLIC4 GIWRYLtNAysRDEFtNtCPsDKEVEIAysDVAKRLTK___
Q9Y696 S245 Sugiyama CLIC4 ysRDEFtNtCPsDKEVEIAysDVAKRLTK____________
Q9Y696 S27 Sugiyama CLIC4 LNGLKEEDKEPLIELFVKAGsDGEsIGNCPFSQRLFMILWL
Q9Y696 S31 Sugiyama CLIC4 KEEDKEPLIELFVKAGsDGEsIGNCPFSQRLFMILWLKGVV
Q9Y6A5 S583 Sugiyama TACC3 ERIC1 FDPLLRDsPGRPVPVATEtssMHGANEtPSGRPREAKLVEF
Q9Y6Q9 S601 SIGNOR|PSP NCOA3 AIB1 BHLHE42 RAC3 TRAM1 EssMCQsNsRDHLSDKESKEsSVEGAENQRGPLESKGHKKL
Q9Y6W5 S474 Sugiyama WASF2 WAVE2 EEQREQEKRDVVGNDVAtILsRRIAVEYsDsEDDssEFDED
Q9Y6W5 T471 Sugiyama WASF2 WAVE2 RRVEEQREQEKRDVVGNDVAtILsRRIAVEYsDsEDDssEF
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Mitotic Prometaphase R-HSA-68877 1.198106e-09 8.922 1 0
M Phase R-HSA-68886 1.718515e-08 7.765 1 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.006284e-08 7.522 0 0
Signal Transduction R-HSA-162582 4.586208e-08 7.339 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.182307e-07 6.927 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.784538e-07 6.748 0 0
Cell Cycle, Mitotic R-HSA-69278 6.239301e-07 6.205 1 0
Cell Cycle R-HSA-1640170 7.211132e-07 6.142 1 0
Mitotic Anaphase R-HSA-68882 2.580252e-06 5.588 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.870440e-06 5.542 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 8.243721e-06 5.084 0 0
Separation of Sister Chromatids R-HSA-2467813 1.169128e-05 4.932 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.161162e-05 4.935 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 2.334908e-05 4.632 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 2.973638e-05 4.527 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.555927e-05 4.449 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 5.578975e-05 4.253 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 5.488478e-05 4.261 0 0
Amplification of signal from the kinetochores R-HSA-141424 5.488478e-05 4.261 0 0
L1CAM interactions R-HSA-373760 6.267246e-05 4.203 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 6.422562e-05 4.192 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 8.239894e-05 4.084 0 0
Membrane Trafficking R-HSA-199991 8.218124e-05 4.085 1 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.104008e-04 3.957 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.210161e-04 3.917 0 0
Axon guidance R-HSA-422475 1.170799e-04 3.932 0 0
Nervous system development R-HSA-9675108 1.203857e-04 3.919 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.324310e-04 3.878 0 0
Apoptotic execution phase R-HSA-75153 1.357071e-04 3.867 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.552879e-04 3.809 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.552879e-04 3.809 0 0
Recycling pathway of L1 R-HSA-437239 1.648865e-04 3.783 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.685374e-04 3.773 0 0
Signaling by Hippo R-HSA-2028269 1.922592e-04 3.716 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.930269e-04 3.714 0 0
MTOR signalling R-HSA-165159 2.064115e-04 3.685 0 0
Mitotic Spindle Checkpoint R-HSA-69618 2.179157e-04 3.662 0 0
Chromatin organization R-HSA-4839726 2.219854e-04 3.654 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.270930e-04 3.644 1 1
IPs transport between nucleus and cytosol R-HSA-1855170 2.492119e-04 3.603 0 0
Mitotic Prophase R-HSA-68875 2.407802e-04 3.618 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 2.556099e-04 3.592 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.119514e-04 3.506 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 3.140974e-04 3.503 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 3.730779e-04 3.428 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.836224e-04 3.416 0 0
Nuclear import of Rev protein R-HSA-180746 3.875886e-04 3.412 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 4.563457e-04 3.341 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 4.546845e-04 3.342 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 5.924703e-04 3.227 0 0
ISG15 antiviral mechanism R-HSA-1169408 6.020956e-04 3.220 0 0
Repression of WNT target genes R-HSA-4641265 6.581930e-04 3.182 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 7.134053e-04 3.147 0 0
NRAGE signals death through JNK R-HSA-193648 7.774626e-04 3.109 0 0
MAPK family signaling cascades R-HSA-5683057 8.419271e-04 3.075 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 9.154385e-04 3.038 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.044089e-03 2.981 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 9.994711e-04 3.000 0 0
mTORC1-mediated signalling R-HSA-166208 1.058803e-03 2.975 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.109033e-03 2.955 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.135536e-03 2.945 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.210387e-03 2.917 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.189833e-03 2.925 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.212860e-03 2.916 1 1
Post NMDA receptor activation events R-HSA-438064 1.241947e-03 2.906 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.337554e-03 2.874 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.273889e-03 2.895 0 0
Signaling by ALK in cancer R-HSA-9700206 1.273889e-03 2.895 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.478217e-03 2.830 0 0
Chromatin modifying enzymes R-HSA-3247509 1.602065e-03 2.795 0 0
DCC mediated attractive signaling R-HSA-418885 1.748753e-03 2.757 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.748753e-03 2.757 0 0
Cell-Cell communication R-HSA-1500931 1.861302e-03 2.730 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 2.170719e-03 2.663 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 2.170719e-03 2.663 0 0
TGFBR3 expression R-HSA-9839394 2.100360e-03 2.678 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 2.061152e-03 2.686 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.108008e-03 2.676 1 1
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.108008e-03 2.676 1 1
EGFR downregulation R-HSA-182971 2.046109e-03 2.689 0 0
Signaling by EGFR R-HSA-177929 2.141009e-03 2.669 0 0
Gap junction trafficking and regulation R-HSA-157858 2.130303e-03 2.672 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 2.100360e-03 2.678 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 2.100360e-03 2.678 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.726452e-03 2.564 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 2.810369e-03 2.551 0 0
Gap junction trafficking R-HSA-190828 2.819971e-03 2.550 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.940332e-03 2.532 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 2.966398e-03 2.528 0 0
snRNP Assembly R-HSA-191859 3.204456e-03 2.494 0 0
Metabolism of non-coding RNA R-HSA-194441 3.204456e-03 2.494 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.049739e-03 2.516 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 3.220039e-03 2.492 0 0
Formation of annular gap junctions R-HSA-196025 3.253841e-03 2.488 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 3.253841e-03 2.488 0 0
Kinesins R-HSA-983189 3.642621e-03 2.439 0 0
Aggrephagy R-HSA-9646399 3.731936e-03 2.428 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 3.958090e-03 2.403 1 1
Viral Messenger RNA Synthesis R-HSA-168325 4.128403e-03 2.384 0 0
Specification of primordial germ cells R-HSA-9827857 3.897730e-03 2.409 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 4.286860e-03 2.368 1 1
tRNA processing in the nucleus R-HSA-6784531 4.665483e-03 2.331 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 4.679996e-03 2.330 0 0
Gap junction degradation R-HSA-190873 4.679996e-03 2.330 0 0
HIV Life Cycle R-HSA-162587 4.753299e-03 2.323 0 0
Oncogenic MAPK signaling R-HSA-6802957 4.755566e-03 2.323 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 4.937646e-03 2.306 0 0
G alpha (12/13) signalling events R-HSA-416482 5.143852e-03 2.289 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 5.332297e-03 2.273 0 0
Clathrin-mediated endocytosis R-HSA-8856828 5.936212e-03 2.226 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 5.882409e-03 2.230 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 5.965304e-03 2.224 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 6.501906e-03 2.187 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 6.501906e-03 2.187 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 6.869446e-03 2.163 1 1
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.986351e-03 2.156 0 0
Death Receptor Signaling R-HSA-73887 7.070092e-03 2.151 0 0
Cell-extracellular matrix interactions R-HSA-446353 7.563066e-03 2.121 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 7.563066e-03 2.121 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 7.626268e-03 2.118 0 0
Nephrin family interactions R-HSA-373753 7.626268e-03 2.118 0 0
Negative regulation of MET activity R-HSA-6807004 7.626268e-03 2.118 0 0
Centrosome maturation R-HSA-380287 8.453091e-03 2.073 1 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 8.304429e-03 2.081 0 0
Nuclear RNA decay R-HSA-9930044 8.989380e-03 2.046 0 0
Deubiquitination R-HSA-5688426 9.441185e-03 2.025 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.020529e-02 1.991 0 0
Regulation of TP53 Activity R-HSA-5633007 1.058437e-02 1.975 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.126697e-02 1.948 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.126697e-02 1.948 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.126697e-02 1.948 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.222161e-02 1.913 1 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.269594e-02 1.896 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.269594e-02 1.896 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.243548e-02 1.905 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.346008e-02 1.871 0 0
Cellular Senescence R-HSA-2559583 1.294312e-02 1.888 0 0
Cilium Assembly R-HSA-5617833 1.372253e-02 1.863 1 0
XBP1(S) activates chaperone genes R-HSA-381038 1.236604e-02 1.908 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.375447e-02 1.862 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.392349e-02 1.856 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.392349e-02 1.856 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.392349e-02 1.856 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.392349e-02 1.856 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.392349e-02 1.856 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.538502e-02 1.813 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 1.682136e-02 1.774 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 1.682136e-02 1.774 0 0
Inositol phosphate metabolism R-HSA-1483249 1.691496e-02 1.772 0 0
Cell junction organization R-HSA-446728 1.839989e-02 1.735 0 0
IRE1alpha activates chaperones R-HSA-381070 2.049760e-02 1.688 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 2.116074e-02 1.674 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.427817e-02 1.615 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.427817e-02 1.615 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.427817e-02 1.615 0 0
MHC class II antigen presentation R-HSA-2132295 2.283963e-02 1.641 0 0
Signaling by RAS mutants R-HSA-6802949 2.427817e-02 1.615 0 0
Long-term potentiation R-HSA-9620244 2.205676e-02 1.656 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 2.297176e-02 1.639 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 2.336343e-02 1.631 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 2.336343e-02 1.631 0 0
Signaling by TGFBR3 R-HSA-9839373 2.427817e-02 1.615 0 0
Autophagy R-HSA-9612973 2.466407e-02 1.608 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.504924e-02 1.601 0 0
NrCAM interactions R-HSA-447038 2.504924e-02 1.601 0 0
Formation of definitive endoderm R-HSA-9823730 2.539604e-02 1.595 0 0
Myogenesis R-HSA-525793 2.559443e-02 1.592 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 2.644002e-02 1.578 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.812806e-02 1.551 0 0
HCMV Early Events R-HSA-9609690 3.078917e-02 1.512 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.947535e-02 1.531 0 0
Breakdown of the nuclear lamina R-HSA-352238 2.956789e-02 1.529 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.956674e-02 1.529 0 0
Selective autophagy R-HSA-9663891 2.907770e-02 1.536 0 0
Gap junction assembly R-HSA-190861 3.181628e-02 1.497 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.959751e-02 1.529 0 0
Vesicle-mediated transport R-HSA-5653656 2.934257e-02 1.533 1 0
Signaling by TGFB family members R-HSA-9006936 3.084664e-02 1.511 0 0
Signaling by MET R-HSA-6806834 2.792507e-02 1.554 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 2.990213e-02 1.524 0 0
G2/M Transition R-HSA-69275 2.974546e-02 1.527 1 0
Organelle biogenesis and maintenance R-HSA-1852241 3.204707e-02 1.494 1 0
COPI-mediated anterograde transport R-HSA-6807878 3.217263e-02 1.493 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.217263e-02 1.493 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.451542e-02 1.462 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.490224e-02 1.457 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 3.507539e-02 1.455 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 3.507539e-02 1.455 0 0
Oncogene Induced Senescence R-HSA-2559585 3.582169e-02 1.446 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 3.910390e-02 1.408 0 0
HATs acetylate histones R-HSA-3214847 3.957027e-02 1.403 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 4.041112e-02 1.393 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.963422e-02 1.304 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.963422e-02 1.304 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.963422e-02 1.304 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.963422e-02 1.304 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.963422e-02 1.304 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.963422e-02 1.304 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.963422e-02 1.304 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.963422e-02 1.304 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.963422e-02 1.304 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 4.963422e-02 1.304 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.963422e-02 1.304 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.963422e-02 1.304 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 4.686331e-02 1.329 0 0
Signaling by AMER1 mutants R-HSA-4839748 4.579737e-02 1.339 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 4.644053e-02 1.333 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 4.482140e-02 1.349 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 4.864081e-02 1.313 0 0
EPHB-mediated forward signaling R-HSA-3928662 4.487853e-02 1.348 0 0
Regulation of TP53 Expression R-HSA-6804754 4.963422e-02 1.304 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.811969e-02 1.318 0 0
Netrin-1 signaling R-HSA-373752 4.487853e-02 1.348 0 0
Regulation of PTEN gene transcription R-HSA-8943724 4.299678e-02 1.367 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.579737e-02 1.339 0 0
Macroautophagy R-HSA-1632852 4.655268e-02 1.332 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 5.286141e-02 1.277 0 0
Deadenylation of mRNA R-HSA-429947 5.299913e-02 1.276 0 0
HIV Infection R-HSA-162906 5.507020e-02 1.259 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 5.544257e-02 1.256 0 0
Signaling by LTK R-HSA-9842663 5.544257e-02 1.256 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 5.594182e-02 1.252 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 5.739854e-02 1.241 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 6.609356e-02 1.180 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 6.419172e-02 1.193 0 0
IGF1R signaling cascade R-HSA-2428924 5.949535e-02 1.226 0 0
FGFR1 mutant receptor activation R-HSA-1839124 6.136281e-02 1.212 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 6.772292e-02 1.169 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 6.009245e-02 1.221 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 6.136281e-02 1.212 0 0
ER to Golgi Anterograde Transport R-HSA-199977 6.638931e-02 1.178 1 0
TCF dependent signaling in response to WNT R-HSA-201681 6.304218e-02 1.200 0 0
Estrogen-dependent gene expression R-HSA-9018519 5.832055e-02 1.234 0 0
PKMTs methylate histone lysines R-HSA-3214841 6.697343e-02 1.174 0 0
HDMs demethylate histones R-HSA-3214842 6.009245e-02 1.221 0 0
Ub-specific processing proteases R-HSA-5689880 6.185102e-02 1.209 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 6.136281e-02 1.212 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 6.136281e-02 1.212 0 0
Developmental Biology R-HSA-1266738 6.046689e-02 1.218 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 6.034218e-02 1.219 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 6.609356e-02 1.180 0 0
Gene Silencing by RNA R-HSA-211000 6.895095e-02 1.161 0 0
NGF-stimulated transcription R-HSA-9031628 6.489689e-02 1.188 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 6.761994e-02 1.170 0 0
Signaling by NTRKs R-HSA-166520 6.963585e-02 1.157 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 6.232409e-02 1.205 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 6.136281e-02 1.212 0 0
Cellular response to heat stress R-HSA-3371556 6.014412e-02 1.221 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 6.136281e-02 1.212 0 0
Host Interactions of HIV factors R-HSA-162909 7.059431e-02 1.151 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 7.282255e-02 1.138 0 0
Signaling by FGFR1 amplification mutants R-HSA-1839120 7.326231e-02 1.135 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 7.326231e-02 1.135 0 0
MET interacts with TNS proteins R-HSA-8875513 7.326231e-02 1.135 0 0
MAP2K and MAPK activation R-HSA-5674135 7.340325e-02 1.134 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 7.368378e-02 1.133 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 7.368378e-02 1.133 0 0
Signal transduction by L1 R-HSA-445144 7.368378e-02 1.133 0 0
Type I hemidesmosome assembly R-HSA-446107 7.541523e-02 1.123 0 0
Interaction between L1 and Ankyrins R-HSA-445095 7.588992e-02 1.120 0 0
CRMPs in Sema3A signaling R-HSA-399956 7.772616e-02 1.109 0 0
Regulation of KIT signaling R-HSA-1433559 7.772616e-02 1.109 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 7.772616e-02 1.109 0 0
Signaling by WNT R-HSA-195721 8.434596e-02 1.074 0 0
Deletions in the AMER1 gene destabilize the destruction complex R-HSA-5467343 8.469284e-02 1.072 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 8.469284e-02 1.072 0 0
Apoptosis R-HSA-109581 8.503680e-02 1.070 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 8.530917e-02 1.069 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 8.534318e-02 1.069 0 0
TBC/RABGAPs R-HSA-8854214 8.734489e-02 1.059 0 0
HCMV Infection R-HSA-9609646 9.020072e-02 1.045 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 9.059946e-02 1.043 0 0
Regulation of TP53 Degradation R-HSA-6804757 9.110339e-02 1.040 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 9.122918e-02 1.040 0 0
Regulation of gap junction activity R-HSA-191650 9.970576e-02 1.001 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 9.970576e-02 1.001 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 9.970576e-02 1.001 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 9.970576e-02 1.001 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 9.196680e-02 1.036 0 0
ARMS-mediated activation R-HSA-170984 9.196680e-02 1.036 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 9.196680e-02 1.036 0 0
ALK mutants bind TKIs R-HSA-9700645 9.196680e-02 1.036 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.035598e-01 0.985 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.138089e-01 0.944 0 0
Signal attenuation R-HSA-74749 1.098682e-01 0.959 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 1.035598e-01 0.985 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 1.037939e-01 0.984 0 0
Trafficking of AMPA receptors R-HSA-399719 1.138089e-01 0.944 0 0
Developmental Cell Lineages R-HSA-9734767 9.971592e-02 1.001 0 0
PTEN Regulation R-HSA-6807070 1.057725e-01 0.976 0 0
Semaphorin interactions R-HSA-373755 1.043082e-01 0.982 0 0
Negative regulation of FLT3 R-HSA-9706369 1.037939e-01 0.984 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 9.381623e-02 1.028 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 9.357162e-02 1.029 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 9.357162e-02 1.029 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.064092e-01 0.973 0 0
Cell-cell junction organization R-HSA-421270 9.333906e-02 1.030 0 0
Reproduction R-HSA-1474165 1.041926e-01 0.982 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 9.381623e-02 1.028 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 9.750169e-02 1.011 0 0
ESR-mediated signaling R-HSA-8939211 1.142764e-01 0.942 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 9.960906e-02 1.002 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 1.037206e-01 0.984 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.037939e-01 0.984 0 0
Cell Cycle Checkpoints R-HSA-69620 1.173339e-01 0.931 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 1.176735e-01 0.929 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.176735e-01 0.929 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 1.178690e-01 0.929 0 0
Signaling by ALK R-HSA-201556 1.178690e-01 0.929 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.181389e-01 0.928 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 1.181389e-01 0.928 1 1
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.181389e-01 0.928 0 0
Adherens junctions interactions R-HSA-418990 1.185307e-01 0.926 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 1.195045e-01 0.923 0 0
Glycolysis R-HSA-70171 1.221970e-01 0.913 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.228529e-01 0.911 0 0
Diseases of mitotic cell cycle R-HSA-9675126 1.245492e-01 0.905 0 0
Rab regulation of trafficking R-HSA-9007101 1.267192e-01 0.897 0 0
Generation of second messenger molecules R-HSA-202433 1.276062e-01 0.894 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.622174e-01 0.790 0 0
IRS activation R-HSA-74713 1.283189e-01 0.892 0 0
G2 Phase R-HSA-68911 1.283189e-01 0.892 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 1.283189e-01 0.892 0 0
PKB-mediated events R-HSA-109703 1.585452e-01 0.800 0 0
PDE3B signalling R-HSA-165160 1.585452e-01 0.800 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 1.585452e-01 0.800 0 0
Signaling by APC mutants R-HSA-4839744 1.289824e-01 0.889 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 1.289824e-01 0.889 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 1.289824e-01 0.889 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 1.289824e-01 0.889 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 1.491683e-01 0.826 0 0
Activation of RAC1 R-HSA-428540 1.491683e-01 0.826 0 0
Signaling by GSK3beta mutants R-HSA-5339716 1.491683e-01 0.826 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.702834e-01 0.769 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.702834e-01 0.769 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.702834e-01 0.769 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 1.702834e-01 0.769 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.702834e-01 0.769 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 1.702834e-01 0.769 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 1.702834e-01 0.769 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 1.702834e-01 0.769 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 1.702834e-01 0.769 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.332877e-01 0.875 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.491817e-01 0.826 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.302547e-01 0.885 0 0
Striated Muscle Contraction R-HSA-390522 1.474354e-01 0.831 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 1.595425e-01 0.797 0 0
mRNA 3'-end processing R-HSA-72187 1.672698e-01 0.777 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.672698e-01 0.777 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.634645e-01 0.787 0 0
PKR-mediated signaling R-HSA-9833482 1.630142e-01 0.788 0 0
Nucleotide Excision Repair R-HSA-5696398 1.618866e-01 0.791 0 0
Integrin signaling R-HSA-354192 1.357642e-01 0.867 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.482404e-01 0.829 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 1.302547e-01 0.885 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.702834e-01 0.769 0 0
Signaling by ERBB2 R-HSA-1227986 1.541400e-01 0.812 0 0
Neurodegenerative Diseases R-HSA-8863678 1.302547e-01 0.885 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.302547e-01 0.885 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 1.491817e-01 0.826 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.289824e-01 0.889 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.376484e-01 0.861 0 0
MET activates RAS signaling R-HSA-8851805 1.702834e-01 0.769 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.434150e-01 0.843 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 1.283189e-01 0.892 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 1.657588e-01 0.781 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 1.585452e-01 0.800 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 1.571217e-01 0.804 0 0
Inhibition of PKR R-HSA-169131 1.622174e-01 0.790 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.491683e-01 0.826 0 0
Signaling by AXIN mutants R-HSA-4839735 1.491683e-01 0.826 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 1.289824e-01 0.889 0 0
FLT3 Signaling R-HSA-9607240 1.377341e-01 0.861 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.585452e-01 0.800 0 0
MAP kinase activation R-HSA-450294 1.634645e-01 0.787 0 0
Interleukin-15 signaling R-HSA-8983432 1.702834e-01 0.769 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.357642e-01 0.867 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.402602e-01 0.853 0 0
Interleukin-7 signaling R-HSA-1266695 1.434150e-01 0.843 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.347421e-01 0.870 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.491817e-01 0.826 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.701178e-01 0.769 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.422882e-01 0.847 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.713401e-01 0.766 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 1.713401e-01 0.766 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 1.777440e-01 0.750 0 0
Meiotic synapsis R-HSA-1221632 1.777440e-01 0.750 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.829547e-01 0.738 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.829547e-01 0.738 0 0
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) R-HSA-5619045 2.331800e-01 0.632 0 0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) R-HSA-5619111 2.331800e-01 0.632 0 0
Defective SLC34A2 causes PALM R-HSA-5687583 2.331800e-01 0.632 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.331800e-01 0.632 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.331800e-01 0.632 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 2.981358e-01 0.526 0 0
Regulation of cortical dendrite branching R-HSA-8985801 2.981358e-01 0.526 0 0
Interaction between PHLDA1 and AURKA R-HSA-8854521 2.981358e-01 0.526 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 2.981358e-01 0.526 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 2.981358e-01 0.526 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 2.981358e-01 0.526 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 1.899067e-01 0.721 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 1.899067e-01 0.721 0 0
Autointegration results in viral DNA circles R-HSA-177539 1.899067e-01 0.721 0 0
Branched-chain ketoacid dehydrogenase kinase deficiency R-HSA-9912481 1.899067e-01 0.721 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 2.219945e-01 0.654 0 0
Disinhibition of SNARE formation R-HSA-114516 2.219945e-01 0.654 0 0
SOS-mediated signalling R-HSA-112412 2.219945e-01 0.654 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 2.219945e-01 0.654 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 2.219945e-01 0.654 0 0
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336 3.575928e-01 0.447 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 3.575928e-01 0.447 0 0
Defective SLC7A7 causes lysinuric protein intolerance (LPI) R-HSA-5660862 3.575928e-01 0.447 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 2.544611e-01 0.594 0 0
MET receptor recycling R-HSA-8875656 2.544611e-01 0.594 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.921871e-01 0.716 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.921871e-01 0.716 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 2.147420e-01 0.668 0 0
WNT mediated activation of DVL R-HSA-201688 2.870123e-01 0.542 0 0
Calcineurin activates NFAT R-HSA-2025928 2.870123e-01 0.542 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 4.120162e-01 0.385 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 4.120162e-01 0.385 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 4.120162e-01 0.385 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 4.120162e-01 0.385 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 2.378160e-01 0.624 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 2.378160e-01 0.624 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 2.378160e-01 0.624 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 3.194012e-01 0.496 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 3.194012e-01 0.496 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 2.612830e-01 0.583 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 2.612830e-01 0.583 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 2.612830e-01 0.583 0 0
HIV elongation arrest and recovery R-HSA-167287 1.860335e-01 0.730 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.860335e-01 0.730 0 0
Late endosomal microautophagy R-HSA-9615710 2.011636e-01 0.696 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 3.514217e-01 0.454 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 3.514217e-01 0.454 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 4.618320e-01 0.336 0 0
FGFR1c and Klotho ligand binding and activation R-HSA-190374 4.618320e-01 0.336 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 4.618320e-01 0.336 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 4.618320e-01 0.336 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.758951e-01 0.559 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 2.758951e-01 0.559 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 3.829041e-01 0.417 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 3.829041e-01 0.417 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 3.829041e-01 0.417 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 3.328935e-01 0.478 0 0
Ephrin signaling R-HSA-3928664 3.328935e-01 0.478 0 0
Tight junction interactions R-HSA-420029 2.954160e-01 0.530 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 2.400148e-01 0.620 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 2.183782e-01 0.661 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 3.568235e-01 0.448 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 3.568235e-01 0.448 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.137099e-01 0.383 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 5.074299e-01 0.295 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 5.074299e-01 0.295 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 5.074299e-01 0.295 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 5.074299e-01 0.295 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 5.074299e-01 0.295 0 0
Loss-of-function mutations in DBT cause MSUD2 R-HSA-9865113 5.074299e-01 0.295 0 0
Signaling by MAPK mutants R-HSA-9652817 5.074299e-01 0.295 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 5.074299e-01 0.295 0 0
Loss-of-function mutations in DLD cause MSUD3/DLDD R-HSA-9907570 5.074299e-01 0.295 0 0
RAF activation R-HSA-5673000 2.988723e-01 0.525 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 3.348918e-01 0.475 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 3.348918e-01 0.475 0 0
Co-inhibition by CTLA4 R-HSA-389513 3.806322e-01 0.419 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 3.806322e-01 0.419 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 3.806322e-01 0.419 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 3.806322e-01 0.419 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 3.806322e-01 0.419 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 4.437279e-01 0.353 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 4.437279e-01 0.353 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 2.259256e-01 0.646 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.745683e-01 0.426 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.943510e-01 0.404 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 3.943510e-01 0.404 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.728704e-01 0.325 0 0
Retrograde neurotrophin signalling R-HSA-177504 4.728704e-01 0.325 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 4.728704e-01 0.325 0 0
Signaling by LTK in cancer R-HSA-9842640 5.491669e-01 0.260 0 0
STAT5 Activation R-HSA-9645135 5.491669e-01 0.260 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.491669e-01 0.260 0 0
H139Hfs13* PPM1K causes a mild variant of MSUD R-HSA-9912529 5.491669e-01 0.260 0 0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD R-HSA-9865125 5.491669e-01 0.260 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 5.491669e-01 0.260 0 0
FGFR2 alternative splicing R-HSA-6803529 4.505866e-01 0.346 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 4.022713e-01 0.395 0 0
Erythropoietin activates RAS R-HSA-9027284 5.010705e-01 0.300 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.010705e-01 0.300 0 0
SHC1 events in EGFR signaling R-HSA-180336 5.010705e-01 0.300 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 5.010705e-01 0.300 0 0
Nuclear Receptor transcription pathway R-HSA-383280 3.530985e-01 0.452 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 4.732048e-01 0.325 0 0
Interleukin receptor SHC signaling R-HSA-912526 4.732048e-01 0.325 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 5.282786e-01 0.277 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 5.282786e-01 0.277 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 5.170903e-01 0.286 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 5.544604e-01 0.256 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 5.544604e-01 0.256 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 5.037735e-01 0.298 0 0
Nucleosome assembly R-HSA-774815 5.037735e-01 0.298 0 0
G1/S-Specific Transcription R-HSA-69205 5.277967e-01 0.278 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.858447e-01 0.314 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 5.200801e-01 0.284 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 5.286616e-01 0.277 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 5.286616e-01 0.277 0 0
mRNA Splicing R-HSA-72172 5.144149e-01 0.289 0 0
mRNA Splicing - Major Pathway R-HSA-72163 5.172206e-01 0.286 0 0
Transcription of the HIV genome R-HSA-167172 5.088988e-01 0.293 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 5.095213e-01 0.293 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.978397e-01 0.704 0 0
Adipogenesis R-HSA-9843745 4.278874e-01 0.369 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 2.400148e-01 0.620 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 2.400148e-01 0.620 0 0
EPH-Ephrin signaling R-HSA-2682334 1.989346e-01 0.701 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 2.704699e-01 0.568 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 2.189381e-01 0.660 0 0
G0 and Early G1 R-HSA-1538133 2.487764e-01 0.604 0 0
IRS-mediated signalling R-HSA-112399 3.538570e-01 0.451 0 0
Regulation of endogenous retroelements R-HSA-9842860 4.169207e-01 0.380 0 0
Insulin receptor signalling cascade R-HSA-74751 3.083458e-01 0.511 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 4.909319e-01 0.309 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.978494e-01 0.526 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.692794e-01 0.570 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 3.297556e-01 0.482 0 0
Pexophagy R-HSA-9664873 3.194012e-01 0.496 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 3.194012e-01 0.496 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.758951e-01 0.559 0 0
PI3K Cascade R-HSA-109704 2.572141e-01 0.590 0 0
GAB1 signalosome R-HSA-180292 3.328935e-01 0.478 0 0
Germ layer formation at gastrulation R-HSA-9754189 3.568235e-01 0.448 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.544604e-01 0.256 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 2.219945e-01 0.654 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 2.870123e-01 0.542 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 2.870123e-01 0.542 0 0
PI3K/AKT activation R-HSA-198203 3.194012e-01 0.496 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 3.514217e-01 0.454 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 4.335712e-01 0.363 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 4.909319e-01 0.309 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 2.612830e-01 0.583 0 0
Killing mechanisms R-HSA-9664420 2.612830e-01 0.583 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 5.277967e-01 0.278 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.959439e-01 0.708 0 0
RNA Polymerase III Transcription R-HSA-74158 5.277967e-01 0.278 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 2.219945e-01 0.654 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 4.120162e-01 0.385 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 4.618320e-01 0.336 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 4.137099e-01 0.383 1 1
VLDLR internalisation and degradation R-HSA-8866427 4.137099e-01 0.383 0 0
Meiosis R-HSA-1500620 2.070260e-01 0.684 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 3.151012e-01 0.502 0 0
UCH proteinases R-HSA-5689603 4.657511e-01 0.332 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.390152e-01 0.622 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 3.089289e-01 0.510 0 0
Integration of provirus R-HSA-162592 3.829041e-01 0.417 0 0
Signaling by Insulin receptor R-HSA-74752 5.482318e-01 0.261 0 0
Epigenetic regulation of gene expression R-HSA-212165 2.196047e-01 0.658 0 0
Resolution of D-Loop Structures R-HSA-5693537 4.720560e-01 0.326 0 0
Signaling by WNT in cancer R-HSA-4791275 2.487764e-01 0.604 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 2.378160e-01 0.624 0 0
Formation of the posterior neural plate R-HSA-9832991 3.514217e-01 0.454 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.618320e-01 0.336 0 0
Activation of AKT2 R-HSA-165158 4.618320e-01 0.336 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 3.829041e-01 0.417 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 3.829041e-01 0.417 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 3.328935e-01 0.478 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 3.568235e-01 0.448 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 4.042413e-01 0.393 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 3.943510e-01 0.404 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 4.529245e-01 0.344 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 4.529245e-01 0.344 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 5.544604e-01 0.256 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.544604e-01 0.256 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 5.049677e-01 0.297 0 0
Signaling by ROBO receptors R-HSA-376176 2.514109e-01 0.600 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.943510e-01 0.404 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 3.603563e-01 0.443 0 0
Prolonged ERK activation events R-HSA-169893 2.612830e-01 0.583 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.093266e-01 0.679 0 0
Circadian clock R-HSA-9909396 3.343700e-01 0.476 1 0
Beta-catenin independent WNT signaling R-HSA-3858494 2.852756e-01 0.545 0 0
Regulation of CDH1 Function R-HSA-9764561 3.538570e-01 0.451 0 0
Signaling by SCF-KIT R-HSA-1433557 2.991825e-01 0.524 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 5.382804e-01 0.269 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 2.375921e-01 0.624 0 0
Regulation of CDH11 function R-HSA-9762292 3.194012e-01 0.496 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 3.348918e-01 0.475 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 2.460029e-01 0.609 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 4.275803e-01 0.369 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 5.491669e-01 0.260 0 0
Negative regulation of MAPK pathway R-HSA-5675221 4.366384e-01 0.360 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 2.810185e-01 0.551 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 1.899067e-01 0.721 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 1.899067e-01 0.721 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 2.850244e-01 0.545 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 3.159351e-01 0.500 0 0
Signalling to ERKs R-HSA-187687 5.095213e-01 0.293 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.341898e-01 0.476 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 2.991825e-01 0.524 0 0
Interferon Signaling R-HSA-913531 3.132950e-01 0.504 0 0
Metabolism of RNA R-HSA-8953854 3.667767e-01 0.436 1 0
Ca2+ pathway R-HSA-4086398 1.864410e-01 0.729 0 0
Transport of connexins along the secretory pathway R-HSA-190827 2.331800e-01 0.632 0 0
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis R-HSA-9708296 2.981358e-01 0.526 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 2.981358e-01 0.526 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 2.981358e-01 0.526 0 0
Regulation of PTEN localization R-HSA-8948747 2.219945e-01 0.654 0 0
Type II Na+/Pi cotransporters R-HSA-427589 3.575928e-01 0.447 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.921871e-01 0.716 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.921871e-01 0.716 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.921871e-01 0.716 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 2.870123e-01 0.542 0 0
Cellular response to mitochondrial stress R-HSA-9840373 2.870123e-01 0.542 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 3.194012e-01 0.496 0 0
Bicarbonate transporters R-HSA-425381 3.514217e-01 0.454 0 0
Ionotropic activity of kainate receptors R-HSA-451306 3.514217e-01 0.454 0 0
Reelin signalling pathway R-HSA-8866376 4.618320e-01 0.336 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 3.328935e-01 0.478 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 5.074299e-01 0.295 0 0
Budding and maturation of HIV virion R-HSA-162588 4.140332e-01 0.383 0 0
Intraflagellar transport R-HSA-5620924 3.762351e-01 0.425 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 5.010705e-01 0.300 0 0
TCR signaling R-HSA-202403 5.159280e-01 0.287 0 0
Gene expression (Transcription) R-HSA-74160 3.289680e-01 0.483 0 0
Heme signaling R-HSA-9707616 2.829547e-01 0.548 0 0
Protein folding R-HSA-391251 5.482318e-01 0.261 0 0
p75NTR signals via NF-kB R-HSA-193639 5.010705e-01 0.300 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.194987e-01 0.377 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.999316e-01 0.398 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.850244e-01 0.545 0 0
p75NTR recruits signalling complexes R-HSA-209543 4.137099e-01 0.383 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 2.011636e-01 0.696 0 0
Calmodulin induced events R-HSA-111933 3.331148e-01 0.477 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 2.870123e-01 0.542 0 0
ERK/MAPK targets R-HSA-198753 4.042413e-01 0.393 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 4.519239e-01 0.345 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 5.088988e-01 0.293 0 0
Cellular responses to stress R-HSA-2262752 2.373760e-01 0.625 0 0
CaM pathway R-HSA-111997 3.331148e-01 0.477 0 0
Early Phase of HIV Life Cycle R-HSA-162594 4.042413e-01 0.393 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 2.147420e-01 0.668 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 2.870123e-01 0.542 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 4.120162e-01 0.385 0 0
Muscarinic acetylcholine receptors R-HSA-390648 4.618320e-01 0.336 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 4.137099e-01 0.383 0 0
Disorders of Nervous System Development R-HSA-9697154 4.137099e-01 0.383 0 0
Pervasive developmental disorders R-HSA-9005895 4.137099e-01 0.383 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 2.829547e-01 0.548 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 4.728704e-01 0.325 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 3.606946e-01 0.443 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 4.013378e-01 0.396 1 0
Cellular responses to stimuli R-HSA-8953897 3.624454e-01 0.441 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.311679e-01 0.480 0 0
Mitochondrial biogenesis R-HSA-1592230 4.913915e-01 0.309 0 0
Signaling by NOTCH1 R-HSA-1980143 3.287046e-01 0.483 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 5.519761e-01 0.258 0 0
Signaling by PTK6 R-HSA-8848021 2.955854e-01 0.529 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 2.955854e-01 0.529 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.137099e-01 0.383 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 4.437279e-01 0.353 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 2.677165e-01 0.572 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 5.382804e-01 0.269 0 0
RET signaling R-HSA-8853659 5.277967e-01 0.278 0 0
PI Metabolism R-HSA-1483255 5.424720e-01 0.266 0 0
Ca-dependent events R-HSA-111996 4.536617e-01 0.343 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 4.720560e-01 0.326 0 0
Chaperonin-mediated protein folding R-HSA-390466 4.764537e-01 0.322 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 4.140332e-01 0.383 0 0
Protein-protein interactions at synapses R-HSA-6794362 4.395918e-01 0.357 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.965158e-01 0.402 0 0
DAG and IP3 signaling R-HSA-1489509 5.037735e-01 0.298 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 3.203093e-01 0.494 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 4.598721e-01 0.337 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 1.937579e-01 0.713 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 2.259256e-01 0.646 0 0
Gastrulation R-HSA-9758941 4.090937e-01 0.388 0 0
Signaling by FGFR in disease R-HSA-1226099 3.046426e-01 0.516 0 0
Interleukin-17 signaling R-HSA-448424 2.579377e-01 0.588 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 4.536617e-01 0.343 0 0
Oligomerization of connexins into connexons R-HSA-190704 2.331800e-01 0.632 0 0
Inhibition of membrane repair R-HSA-9635644 2.331800e-01 0.632 0 0
DSCAM interactions R-HSA-376172 2.981358e-01 0.526 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 1.899067e-01 0.721 0 0
2-LTR circle formation R-HSA-164843 3.194012e-01 0.496 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 3.829041e-01 0.417 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 5.074299e-01 0.295 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.074299e-01 0.295 0 0
Disorders of Developmental Biology R-HSA-9675151 5.544604e-01 0.256 0 0
DNA Damage Bypass R-HSA-73893 2.440413e-01 0.613 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 3.348918e-01 0.475 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 4.275803e-01 0.369 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 4.505866e-01 0.346 0 0
HCMV Late Events R-HSA-9610379 4.818606e-01 0.317 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 4.249735e-01 0.372 0 0
MyD88-independent TLR4 cascade R-HSA-166166 5.159280e-01 0.287 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 5.159280e-01 0.287 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 2.544611e-01 0.594 0 0
PECAM1 interactions R-HSA-210990 3.514217e-01 0.454 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 3.572528e-01 0.447 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 2.378160e-01 0.624 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 5.382804e-01 0.269 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.348918e-01 0.475 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 4.973212e-01 0.303 0 0
Signaling by VEGF R-HSA-194138 4.686243e-01 0.329 0 0
SARS-CoV-2-host interactions R-HSA-9705683 3.575570e-01 0.447 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 4.973212e-01 0.303 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 4.973212e-01 0.303 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 4.612764e-01 0.336 0 0
Sodium/Proton exchangers R-HSA-425986 2.544611e-01 0.594 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 4.618320e-01 0.336 0 0
Synaptic adhesion-like molecules R-HSA-8849932 3.328935e-01 0.478 0 0
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397 5.074299e-01 0.295 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.849864e-01 0.415 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 4.529245e-01 0.344 0 0
RUNX2 regulates bone development R-HSA-8941326 5.277967e-01 0.278 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 5.018130e-01 0.299 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 2.571690e-01 0.590 0 0
Miscellaneous transport and binding events R-HSA-5223345 4.720560e-01 0.326 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.310893e-01 0.636 0 0
Programmed Cell Death R-HSA-5357801 3.481312e-01 0.458 0 0
Cytokine Signaling in Immune system R-HSA-1280215 3.868258e-01 0.412 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 2.870123e-01 0.542 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 3.514217e-01 0.454 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 4.618320e-01 0.336 0 0
Signal regulatory protein family interactions R-HSA-391160 4.728704e-01 0.325 0 0
Formation of the anterior neural plate R-HSA-9823739 5.010705e-01 0.300 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 5.010705e-01 0.300 0 0
Syndecan interactions R-HSA-3000170 4.732048e-01 0.325 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 3.676761e-01 0.435 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 3.538570e-01 0.451 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.144098e-01 0.503 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 5.282786e-01 0.277 0 0
tRNA processing R-HSA-72306 5.060192e-01 0.296 0 0
TNF signaling R-HSA-75893 3.397216e-01 0.469 0 0
Josephin domain DUBs R-HSA-5689877 3.194012e-01 0.496 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.189381e-01 0.660 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 5.246840e-01 0.280 0 0
ChREBP activates metabolic gene expression R-HSA-163765 3.514217e-01 0.454 0 0
Regulation of TNFR1 signaling R-HSA-5357905 5.200801e-01 0.284 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 5.074299e-01 0.295 0 0
Neurofascin interactions R-HSA-447043 5.491669e-01 0.260 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 5.010705e-01 0.300 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 4.618320e-01 0.336 0 0
Assembly Of The HIV Virion R-HSA-175474 4.275803e-01 0.369 0 0
Glucose metabolism R-HSA-70326 2.756954e-01 0.560 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.282786e-01 0.277 0 0
Signaling by Leptin R-HSA-2586552 3.194012e-01 0.496 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.265347e-01 0.645 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 2.481150e-01 0.605 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 5.574740e-01 0.254 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 5.589274e-01 0.253 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 5.589274e-01 0.253 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 5.589274e-01 0.253 0 0
Insulin processing R-HSA-264876 5.589274e-01 0.253 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 5.663788e-01 0.247 0 0
Degradation of CDH1 R-HSA-9766229 5.675308e-01 0.246 0 0
SLC transporter disorders R-HSA-5619102 5.703759e-01 0.244 0 0
PLC beta mediated events R-HSA-112043 5.715679e-01 0.243 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 5.753315e-01 0.240 0 0
Activation of HOX genes during differentiation R-HSA-5619507 5.753315e-01 0.240 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 5.790070e-01 0.237 0 0
Formation of the Early Elongation Complex R-HSA-113418 5.790070e-01 0.237 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 5.790070e-01 0.237 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 5.790070e-01 0.237 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 5.790070e-01 0.237 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 5.791389e-01 0.237 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 5.795946e-01 0.237 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 5.795946e-01 0.237 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 5.795946e-01 0.237 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 5.795946e-01 0.237 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 5.795946e-01 0.237 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 5.795946e-01 0.237 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 5.795946e-01 0.237 0 0
Uptake and function of anthrax toxins R-HSA-5210891 5.795946e-01 0.237 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 5.805070e-01 0.236 0 0
Stabilization of p53 R-HSA-69541 5.805070e-01 0.236 0 0
Signaling by Interleukins R-HSA-449147 5.812772e-01 0.236 0 0
Influenza Infection R-HSA-168255 5.824718e-01 0.235 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 5.854377e-01 0.233 0 0
Signaling by Nuclear Receptors R-HSA-9006931 5.854570e-01 0.233 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 5.873697e-01 0.231 0 0
IFNG signaling activates MAPKs R-HSA-9732724 5.873697e-01 0.231 0 0
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974 5.873697e-01 0.231 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 5.873697e-01 0.231 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.873697e-01 0.231 0 0
Netrin mediated repulsion signals R-HSA-418886 5.873697e-01 0.231 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 5.873697e-01 0.231 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 5.873697e-01 0.231 0 0
VLDL clearance R-HSA-8964046 5.873697e-01 0.231 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 5.873697e-01 0.231 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 5.873697e-01 0.231 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 5.973085e-01 0.224 0 0
HIV Transcription Elongation R-HSA-167169 5.973085e-01 0.224 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 5.973085e-01 0.224 0 0
Interleukin-2 family signaling R-HSA-451927 5.973085e-01 0.224 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 5.984997e-01 0.223 0 0
Termination of translesion DNA synthesis R-HSA-5656169 5.984997e-01 0.223 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 5.984997e-01 0.223 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 6.008076e-01 0.221 0 0
FGFR1 ligand binding and activation R-HSA-190242 6.036706e-01 0.219 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 6.036706e-01 0.219 0 0
Chaperone Mediated Autophagy R-HSA-9613829 6.036706e-01 0.219 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 6.049224e-01 0.218 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 6.124507e-01 0.213 0 0
Ion transport by P-type ATPases R-HSA-936837 6.124634e-01 0.213 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 6.173910e-01 0.209 0 0
Activation of BH3-only proteins R-HSA-114452 6.173910e-01 0.209 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 6.173910e-01 0.209 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 6.174720e-01 0.209 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 6.223373e-01 0.206 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 6.223373e-01 0.206 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 6.223373e-01 0.206 0 0
FGFR1b ligand binding and activation R-HSA-190370 6.223373e-01 0.206 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 6.223373e-01 0.206 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 6.223373e-01 0.206 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 6.223373e-01 0.206 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 6.223373e-01 0.206 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 6.223373e-01 0.206 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 6.223373e-01 0.206 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 6.223373e-01 0.206 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 6.223373e-01 0.206 0 0
Alpha-defensins R-HSA-1462054 6.223373e-01 0.206 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 6.223373e-01 0.206 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 6.256011e-01 0.204 0 0
Regulation of signaling by CBL R-HSA-912631 6.266872e-01 0.203 0 0
Rap1 signalling R-HSA-392517 6.266872e-01 0.203 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.266872e-01 0.203 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.266872e-01 0.203 0 0
STING mediated induction of host immune responses R-HSA-1834941 6.266872e-01 0.203 0 0
Smooth Muscle Contraction R-HSA-445355 6.268039e-01 0.203 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 6.276721e-01 0.202 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 6.289544e-01 0.201 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 6.289544e-01 0.201 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 6.296720e-01 0.201 0 0
HIV Transcription Initiation R-HSA-167161 6.296720e-01 0.201 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 6.296720e-01 0.201 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 6.296720e-01 0.201 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 6.334877e-01 0.198 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 6.356702e-01 0.197 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 6.356702e-01 0.197 0 0
PCP/CE pathway R-HSA-4086400 6.373446e-01 0.196 0 0
Translation initiation complex formation R-HSA-72649 6.408317e-01 0.193 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 6.419875e-01 0.192 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 6.480075e-01 0.188 0 0
Chromosome Maintenance R-HSA-73886 6.480075e-01 0.188 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 6.486512e-01 0.188 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 6.486512e-01 0.188 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 6.486512e-01 0.188 0 0
Signaling by NODAL R-HSA-1181150 6.486512e-01 0.188 0 0
Protein hydroxylation R-HSA-9629569 6.486512e-01 0.188 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.486512e-01 0.188 0 0
Sensory processing of sound R-HSA-9659379 6.490869e-01 0.188 0 0
G-protein mediated events R-HSA-112040 6.510886e-01 0.186 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 6.533305e-01 0.185 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 6.543435e-01 0.184 0 0
Lipophagy R-HSA-9613354 6.543435e-01 0.184 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 6.543435e-01 0.184 0 0
p75NTR regulates axonogenesis R-HSA-193697 6.543435e-01 0.184 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 6.543435e-01 0.184 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.543435e-01 0.184 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 6.543435e-01 0.184 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 6.573318e-01 0.182 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 6.573318e-01 0.182 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 6.578575e-01 0.182 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 6.603183e-01 0.180 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 6.669997e-01 0.176 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 6.678833e-01 0.175 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 6.678833e-01 0.175 0 0
Signaling by FGFR1 R-HSA-5654736 6.678833e-01 0.175 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 6.678833e-01 0.175 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 6.695756e-01 0.174 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 6.695756e-01 0.174 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 6.695756e-01 0.174 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 6.695756e-01 0.174 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 6.695756e-01 0.174 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 6.695756e-01 0.174 0 0
Basigin interactions R-HSA-210991 6.695756e-01 0.174 0 0
G-protein beta:gamma signalling R-HSA-397795 6.703684e-01 0.174 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 6.703684e-01 0.174 0 0
Cardiogenesis R-HSA-9733709 6.703684e-01 0.174 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 6.703684e-01 0.174 0 0
Cyclin D associated events in G1 R-HSA-69231 6.749811e-01 0.171 0 0
G1 Phase R-HSA-69236 6.749811e-01 0.171 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 6.836390e-01 0.165 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 6.836390e-01 0.165 0 0
DNA replication initiation R-HSA-68952 6.836390e-01 0.165 0 0
Folding of actin by CCT/TriC R-HSA-390450 6.836390e-01 0.165 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 6.836390e-01 0.165 0 0
Binding and entry of HIV virion R-HSA-173107 6.836390e-01 0.165 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 6.836390e-01 0.165 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 6.836390e-01 0.165 0 0
Arachidonate production from DAG R-HSA-426048 6.836390e-01 0.165 0 0
Receptor Mediated Mitophagy R-HSA-8934903 6.836390e-01 0.165 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 6.867837e-01 0.163 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 6.867837e-01 0.163 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 6.891987e-01 0.162 0 0
Fanconi Anemia Pathway R-HSA-6783310 6.891987e-01 0.162 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 6.894788e-01 0.161 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 6.894788e-01 0.161 0 0
Mitochondrial calcium ion transport R-HSA-8949215 6.894788e-01 0.161 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 6.894788e-01 0.161 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 6.912509e-01 0.160 0 0
Transmission across Chemical Synapses R-HSA-112315 6.921332e-01 0.160 0 0
Dual incision in TC-NER R-HSA-6782135 6.935634e-01 0.159 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 6.987592e-01 0.156 0 0
DNA Repair R-HSA-73894 7.005779e-01 0.155 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 7.025788e-01 0.153 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 7.025788e-01 0.153 0 0
NOD1/2 Signaling Pathway R-HSA-168638 7.025788e-01 0.153 0 0
Hyaluronan metabolism R-HSA-2142845 7.025788e-01 0.153 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 7.025788e-01 0.153 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 7.029696e-01 0.153 0 0
S Phase R-HSA-69242 7.071223e-01 0.151 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 7.071223e-01 0.151 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 7.083836e-01 0.150 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 7.083836e-01 0.150 0 0
Notch-HLH transcription pathway R-HSA-350054 7.083836e-01 0.150 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 7.083836e-01 0.150 0 0
Ethanol oxidation R-HSA-71384 7.083836e-01 0.150 0 0
LDL clearance R-HSA-8964038 7.083836e-01 0.150 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 7.083836e-01 0.150 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 7.099668e-01 0.149 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 7.104532e-01 0.148 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 7.104532e-01 0.148 0 0
LGI-ADAM interactions R-HSA-5682910 7.104532e-01 0.148 0 0
Synthesis of PI R-HSA-1483226 7.104532e-01 0.148 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 7.104532e-01 0.148 0 0
Transport of RCbl within the body R-HSA-9758890 7.104532e-01 0.148 0 0
Interleukin-2 signaling R-HSA-9020558 7.104532e-01 0.148 0 0
Dissolution of Fibrin Clot R-HSA-75205 7.104532e-01 0.148 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 7.177584e-01 0.144 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 7.178488e-01 0.144 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 7.178488e-01 0.144 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 7.178488e-01 0.144 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 7.178488e-01 0.144 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 7.178488e-01 0.144 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 7.263162e-01 0.139 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 7.263162e-01 0.139 0 0
Termination of O-glycan biosynthesis R-HSA-977068 7.263162e-01 0.139 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.263162e-01 0.139 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 7.263162e-01 0.139 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 7.263162e-01 0.139 0 0
Carnitine shuttle R-HSA-200425 7.263162e-01 0.139 0 0
Growth hormone receptor signaling R-HSA-982772 7.263162e-01 0.139 0 0
Co-stimulation by CD28 R-HSA-389356 7.291724e-01 0.137 0 0
GPER1 signaling R-HSA-9634597 7.291724e-01 0.137 0 0
RNA Polymerase II Transcription R-HSA-73857 7.313778e-01 0.136 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 7.323296e-01 0.135 0 0
FLT3 signaling in disease R-HSA-9682385 7.323296e-01 0.135 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 7.349962e-01 0.134 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 7.349962e-01 0.134 0 0
NF-kB is activated and signals survival R-HSA-209560 7.349962e-01 0.134 0 0
ERKs are inactivated R-HSA-202670 7.349962e-01 0.134 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 7.349962e-01 0.134 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 7.349962e-01 0.134 0 0
Sodium/Calcium exchangers R-HSA-425561 7.349962e-01 0.134 0 0
NCAM signaling for neurite out-growth R-HSA-375165 7.407329e-01 0.130 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 7.416086e-01 0.130 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 7.416086e-01 0.130 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 7.418573e-01 0.130 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 7.418573e-01 0.130 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.433055e-01 0.129 0 0
Degradation of DVL R-HSA-4641258 7.463011e-01 0.127 0 0
Ovarian tumor domain proteases R-HSA-5689896 7.463011e-01 0.127 0 0
Signaling by FGFR R-HSA-190236 7.470558e-01 0.127 0 0
Interleukin-12 signaling R-HSA-9020591 7.519093e-01 0.124 0 0
Regulation of RAS by GAPs R-HSA-5658442 7.536059e-01 0.123 0 0
FOXO-mediated transcription R-HSA-9614085 7.557899e-01 0.122 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 7.574601e-01 0.121 0 0
Maple Syrup Urine Disease R-HSA-9865114 7.574601e-01 0.121 0 0
Polymerase switching R-HSA-69091 7.574601e-01 0.121 0 0
Leading Strand Synthesis R-HSA-69109 7.574601e-01 0.121 0 0
GRB2 events in EGFR signaling R-HSA-179812 7.574601e-01 0.121 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 7.574601e-01 0.121 0 0
Regulation of IFNG signaling R-HSA-877312 7.574601e-01 0.121 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 7.574601e-01 0.121 0 0
Diseases associated with surfactant metabolism R-HSA-5687613 7.574601e-01 0.121 0 0
OAS antiviral response R-HSA-8983711 7.574601e-01 0.121 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.593827e-01 0.120 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 7.593827e-01 0.120 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 7.593827e-01 0.120 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 7.593827e-01 0.120 0 0
Hyaluronan degradation R-HSA-2160916 7.593827e-01 0.120 0 0
Acyl chain remodelling of PS R-HSA-1482801 7.593827e-01 0.120 0 0
MET promotes cell motility R-HSA-8875878 7.596835e-01 0.119 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 7.596835e-01 0.119 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 7.596835e-01 0.119 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 7.616735e-01 0.118 0 0
HSF1-dependent transactivation R-HSA-3371571 7.651693e-01 0.116 0 0
Plasma lipoprotein clearance R-HSA-8964043 7.724884e-01 0.112 0 0
Signaling by EGFR in Cancer R-HSA-1643713 7.745801e-01 0.111 0 0
Metalloprotease DUBs R-HSA-5689901 7.745801e-01 0.111 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 7.745801e-01 0.111 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 7.745801e-01 0.111 0 0
TRP channels R-HSA-3295583 7.745801e-01 0.111 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 7.745801e-01 0.111 0 0
Formation of axial mesoderm R-HSA-9796292 7.780210e-01 0.109 0 0
FGFR1c ligand binding and activation R-HSA-190373 7.780210e-01 0.109 0 0
Frs2-mediated activation R-HSA-170968 7.780210e-01 0.109 0 0
Processing of SMDT1 R-HSA-8949664 7.780210e-01 0.109 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 7.799927e-01 0.108 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 7.847291e-01 0.105 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 7.847291e-01 0.105 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 7.847291e-01 0.105 0 0
Glycogen metabolism R-HSA-8982491 7.847291e-01 0.105 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 7.870189e-01 0.104 0 0
Regulation of PTEN stability and activity R-HSA-8948751 7.870189e-01 0.104 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 7.889314e-01 0.103 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.889314e-01 0.103 0 0
Signaling by FGFR2 R-HSA-5654738 7.892569e-01 0.103 0 0
Opioid Signalling R-HSA-111885 7.962452e-01 0.099 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 7.964193e-01 0.099 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 7.964193e-01 0.099 0 0
Removal of the Flap Intermediate R-HSA-69166 7.968401e-01 0.099 0 0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV R-HSA-9859138 7.968401e-01 0.099 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 7.968401e-01 0.099 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 7.968401e-01 0.099 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 7.968401e-01 0.099 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 7.968401e-01 0.099 0 0
Processing of DNA double-strand break ends R-HSA-5693607 7.978900e-01 0.098 0 0
Telomere Extension By Telomerase R-HSA-171319 8.024709e-01 0.096 0 0
HDACs deacetylate histones R-HSA-3214815 8.072136e-01 0.093 0 0
Signaling by NOTCH3 R-HSA-9012852 8.072136e-01 0.093 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 8.119930e-01 0.090 0 0
Processive synthesis on the lagging strand R-HSA-69183 8.140647e-01 0.089 0 0
Telomere C-strand synthesis initiation R-HSA-174430 8.140647e-01 0.089 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 8.140647e-01 0.089 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 8.140647e-01 0.089 0 0
Spry regulation of FGF signaling R-HSA-1295596 8.140647e-01 0.089 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 8.140647e-01 0.089 0 0
Other semaphorin interactions R-HSA-416700 8.140647e-01 0.089 0 0
Biotin transport and metabolism R-HSA-196780 8.140647e-01 0.089 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.143334e-01 0.089 0 0
Signaling by Erythropoietin R-HSA-9006335 8.152328e-01 0.089 0 0
mRNA Capping R-HSA-72086 8.152328e-01 0.089 0 0
Regulation of gene expression in beta cells R-HSA-210745 8.152328e-01 0.089 0 0
Platelet calcium homeostasis R-HSA-418360 8.152328e-01 0.089 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 8.152328e-01 0.089 0 0
Ion homeostasis R-HSA-5578775 8.167109e-01 0.088 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 8.182084e-01 0.087 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 8.184453e-01 0.087 0 0
Leishmania phagocytosis R-HSA-9664417 8.184453e-01 0.087 0 0
Parasite infection R-HSA-9664407 8.184453e-01 0.087 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 8.185905e-01 0.087 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 8.185905e-01 0.087 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 8.239682e-01 0.084 0 0
Homology Directed Repair R-HSA-5693538 8.240439e-01 0.084 0 0
DNA Double-Strand Break Repair R-HSA-5693532 8.252718e-01 0.083 0 0
DAP12 signaling R-HSA-2424491 8.272518e-01 0.082 0 0
Activation of the pre-replicative complex R-HSA-68962 8.272518e-01 0.082 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 8.272518e-01 0.082 0 0
Interleukin-37 signaling R-HSA-9008059 8.272518e-01 0.082 0 0
Signaling by NOTCH R-HSA-157118 8.277673e-01 0.082 0 0
Signaling by FGFR4 R-HSA-5654743 8.283387e-01 0.082 0 0
Phosphorylation of the APC/C R-HSA-176412 8.298299e-01 0.081 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 8.298299e-01 0.081 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 8.298299e-01 0.081 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 8.298299e-01 0.081 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 8.298299e-01 0.081 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 8.298299e-01 0.081 0 0
Fructose catabolism R-HSA-70350 8.298299e-01 0.081 0 0
Differentiation of T cells R-HSA-9945266 8.298299e-01 0.081 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 8.298299e-01 0.081 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 8.298299e-01 0.081 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 8.303883e-01 0.081 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 8.348071e-01 0.078 0 0
Surfactant metabolism R-HSA-5683826 8.379810e-01 0.077 0 0
RMTs methylate histone arginines R-HSA-3214858 8.379810e-01 0.077 0 0
Cargo concentration in the ER R-HSA-5694530 8.385620e-01 0.076 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 8.429129e-01 0.074 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 8.442592e-01 0.074 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 8.442592e-01 0.074 0 0
Phase 2 - plateau phase R-HSA-5576893 8.442592e-01 0.074 0 0
Fibronectin matrix formation R-HSA-1566977 8.442592e-01 0.074 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 8.442592e-01 0.074 0 0
tRNA modification in the mitochondrion R-HSA-6787450 8.442592e-01 0.074 0 0
Coenzyme A biosynthesis R-HSA-196783 8.442592e-01 0.074 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 8.442592e-01 0.074 0 0
Signaling by FGFR3 R-HSA-5654741 8.471519e-01 0.072 0 0
Signaling by ERBB4 R-HSA-1236394 8.498185e-01 0.071 0 0
Interleukin-12 family signaling R-HSA-447115 8.508365e-01 0.070 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 8.509163e-01 0.070 0 0
Generic Transcription Pathway R-HSA-212436 8.520440e-01 0.070 0 0
Adaptive Immune System R-HSA-1280218 8.551866e-01 0.068 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 8.558681e-01 0.068 0 0
Diseases of DNA repair R-HSA-9675135 8.558681e-01 0.068 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 8.562272e-01 0.067 0 0
Protein ubiquitination R-HSA-8852135 8.568895e-01 0.067 0 0
Diseases of programmed cell death R-HSA-9645723 8.573853e-01 0.067 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 8.574658e-01 0.067 0 0
Glycogen storage diseases R-HSA-3229121 8.574658e-01 0.067 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 8.574658e-01 0.067 0 0
Hedgehog 'off' state R-HSA-5610787 8.591698e-01 0.066 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 8.614888e-01 0.065 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 8.641462e-01 0.063 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 8.672340e-01 0.062 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 8.672340e-01 0.062 0 0
Effects of PIP2 hydrolysis R-HSA-114508 8.685742e-01 0.061 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.685742e-01 0.061 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 8.695532e-01 0.061 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 8.695532e-01 0.061 0 0
Presynaptic function of Kainate receptors R-HSA-500657 8.695532e-01 0.061 0 0
Polo-like kinase mediated events R-HSA-156711 8.695532e-01 0.061 0 0
Platelet sensitization by LDL R-HSA-432142 8.695532e-01 0.061 0 0
Tie2 Signaling R-HSA-210993 8.695532e-01 0.061 0 0
G1/S Transition R-HSA-69206 8.699418e-01 0.061 0 0
Muscle contraction R-HSA-397014 8.708984e-01 0.060 0 0
Metal ion SLC transporters R-HSA-425410 8.720030e-01 0.059 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 8.728784e-01 0.059 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 8.728784e-01 0.059 0 0
Potential therapeutics for SARS R-HSA-9679191 8.762090e-01 0.057 0 0
Dual Incision in GG-NER R-HSA-5696400 8.773799e-01 0.057 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 8.773799e-01 0.057 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 8.773799e-01 0.057 0 0
Mitophagy R-HSA-5205647 8.773799e-01 0.057 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.773799e-01 0.057 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 8.795515e-01 0.056 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 8.806162e-01 0.055 0 0
Pyrimidine biosynthesis R-HSA-500753 8.806162e-01 0.055 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 8.806162e-01 0.055 0 0
The NLRP3 inflammasome R-HSA-844456 8.806162e-01 0.055 0 0
Other interleukin signaling R-HSA-449836 8.806162e-01 0.055 0 0
Specification of the neural plate border R-HSA-9834899 8.806162e-01 0.055 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 8.806162e-01 0.055 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 8.824446e-01 0.054 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 8.856380e-01 0.053 0 0
Regulation of Apoptosis R-HSA-169911 8.856380e-01 0.053 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 8.856380e-01 0.053 0 0
Toll-like Receptor Cascades R-HSA-168898 8.863487e-01 0.052 0 0
Cellular response to chemical stress R-HSA-9711123 8.876012e-01 0.052 0 0
Glycogen synthesis R-HSA-3322077 8.907416e-01 0.050 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.909069e-01 0.050 0 0
Meiotic recombination R-HSA-912446 8.932099e-01 0.049 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 8.932099e-01 0.049 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 8.933781e-01 0.049 0 0
Glycosphingolipid transport R-HSA-9845576 8.933781e-01 0.049 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.933781e-01 0.049 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.933781e-01 0.049 0 0
DNA Double Strand Break Response R-HSA-5693606 8.977756e-01 0.047 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 8.977756e-01 0.047 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 8.995449e-01 0.046 0 0
Neurexins and neuroligins R-HSA-6794361 8.995449e-01 0.046 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 8.995449e-01 0.046 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 8.995449e-01 0.046 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 9.000088e-01 0.046 0 0
Lagging Strand Synthesis R-HSA-69186 9.000088e-01 0.046 0 0
G-protein activation R-HSA-202040 9.000088e-01 0.046 0 0
Signalling to RAS R-HSA-167044 9.000088e-01 0.046 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 9.000088e-01 0.046 0 0
Abacavir metabolism R-HSA-2161541 9.000088e-01 0.046 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 9.000088e-01 0.046 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 9.000088e-01 0.046 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.006286e-01 0.045 0 0
NCAM1 interactions R-HSA-419037 9.006286e-01 0.045 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.055390e-01 0.043 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 9.055390e-01 0.043 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 9.055390e-01 0.043 0 0
Elastic fibre formation R-HSA-1566948 9.074168e-01 0.042 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.074168e-01 0.042 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.084904e-01 0.042 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 9.084904e-01 0.042 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 9.084904e-01 0.042 0 0
Ribavirin ADME R-HSA-9755088 9.084904e-01 0.042 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 9.084904e-01 0.042 0 0
Glutathione synthesis and recycling R-HSA-174403 9.084904e-01 0.042 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 9.088100e-01 0.042 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.094468e-01 0.041 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 9.112076e-01 0.040 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.135261e-01 0.039 0 0
COPII-mediated vesicle transport R-HSA-204005 9.135261e-01 0.039 1 1
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.137690e-01 0.039 0 0
Telomere Maintenance R-HSA-157579 9.149149e-01 0.039 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 9.162531e-01 0.038 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 9.162531e-01 0.038 0 0
Signaling by KIT in disease R-HSA-9669938 9.162531e-01 0.038 0 0
Fructose metabolism R-HSA-5652084 9.162531e-01 0.038 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 9.162531e-01 0.038 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.162531e-01 0.038 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 9.162531e-01 0.038 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 9.165654e-01 0.038 0 0
Paracetamol ADME R-HSA-9753281 9.165654e-01 0.038 0 0
Co-inhibition by PD-1 R-HSA-389948 9.165923e-01 0.038 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.166590e-01 0.038 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 9.182740e-01 0.037 0 0
Regulation of mitotic cell cycle R-HSA-453276 9.182740e-01 0.037 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 9.197102e-01 0.036 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.197102e-01 0.036 0 0
Formation of the cornified envelope R-HSA-6809371 9.202494e-01 0.036 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 9.216268e-01 0.035 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 9.216268e-01 0.035 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.233577e-01 0.035 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 9.233577e-01 0.035 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.233577e-01 0.035 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 9.246677e-01 0.034 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 9.252645e-01 0.034 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.252645e-01 0.034 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.266377e-01 0.033 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.269082e-01 0.033 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.298599e-01 0.032 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 9.298599e-01 0.032 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 9.298599e-01 0.032 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 9.298599e-01 0.032 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.298599e-01 0.032 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 9.298599e-01 0.032 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.298599e-01 0.032 0 0
Interleukin-1 signaling R-HSA-9020702 9.301546e-01 0.031 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 9.304548e-01 0.031 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.304548e-01 0.031 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.305196e-01 0.031 0 0
G2/M DNA damage checkpoint R-HSA-69473 9.311473e-01 0.031 0 0
Peroxisomal protein import R-HSA-9033241 9.351706e-01 0.029 0 0
Extension of Telomeres R-HSA-180786 9.351706e-01 0.029 0 0
Regulation of beta-cell development R-HSA-186712 9.351706e-01 0.029 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.351706e-01 0.029 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.353027e-01 0.029 0 0
Beta-oxidation of pristanoyl-CoA R-HSA-389887 9.358109e-01 0.029 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 9.358109e-01 0.029 0 0
Laminin interactions R-HSA-3000157 9.358109e-01 0.029 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.358109e-01 0.029 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.366393e-01 0.028 0 0
Neuronal System R-HSA-112316 9.387538e-01 0.027 0 0
tRNA Aminoacylation R-HSA-379724 9.391821e-01 0.027 0 0
Response of endothelial cells to shear stress R-HSA-9860931 9.399498e-01 0.027 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.412573e-01 0.026 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.412573e-01 0.026 0 0
Abacavir ADME R-HSA-2161522 9.412573e-01 0.026 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 9.412573e-01 0.026 0 0
Suppression of phagosomal maturation R-HSA-9637687 9.412573e-01 0.026 0 0
Neutrophil degranulation R-HSA-6798695 9.415113e-01 0.026 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.429628e-01 0.026 0 0
DAP12 interactions R-HSA-2172127 9.440534e-01 0.025 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.453815e-01 0.024 0 0
Integrin cell surface interactions R-HSA-216083 9.454556e-01 0.024 0 0
Interleukin-10 signaling R-HSA-6783783 9.454556e-01 0.024 0 0
Cristae formation R-HSA-8949613 9.462418e-01 0.024 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 9.462418e-01 0.024 0 0
Signaling by BMP R-HSA-201451 9.462418e-01 0.024 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.462418e-01 0.024 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.462418e-01 0.024 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 9.465243e-01 0.024 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.479945e-01 0.023 0 0
SARS-CoV-1-host interactions R-HSA-9692914 9.485013e-01 0.023 0 0
Insulin receptor recycling R-HSA-77387 9.508037e-01 0.022 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 9.508037e-01 0.022 0 0
Inflammasomes R-HSA-622312 9.508037e-01 0.022 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 9.508037e-01 0.022 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 9.508037e-01 0.022 0 0
Iron assimilation using enterobactin R-HSA-9638334 9.508037e-01 0.022 0 0
Pyrimidine salvage R-HSA-73614 9.508037e-01 0.022 0 0
Pyroptosis R-HSA-5620971 9.508037e-01 0.022 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.516699e-01 0.022 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 9.516699e-01 0.022 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.516699e-01 0.022 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.536099e-01 0.021 0 0
Amyloid fiber formation R-HSA-977225 9.543418e-01 0.020 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 9.549787e-01 0.020 0 0
DARPP-32 events R-HSA-180024 9.549787e-01 0.020 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.550963e-01 0.020 0 0
Ion channel transport R-HSA-983712 9.553226e-01 0.020 0 0
Cellular response to hypoxia R-HSA-1234174 9.560051e-01 0.020 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 9.569939e-01 0.019 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.587996e-01 0.018 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.587996e-01 0.018 0 0
Integration of energy metabolism R-HSA-163685 9.600615e-01 0.018 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.612645e-01 0.017 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.622965e-01 0.017 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 9.622965e-01 0.017 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.622965e-01 0.017 0 0
Downstream signal transduction R-HSA-186763 9.622965e-01 0.017 0 0
Regulation of insulin secretion R-HSA-422356 9.637321e-01 0.016 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 9.637567e-01 0.016 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 9.637567e-01 0.016 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 9.637567e-01 0.016 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.640351e-01 0.016 0 0
DNA strand elongation R-HSA-69190 9.654967e-01 0.015 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.654967e-01 0.015 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.666147e-01 0.015 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.666147e-01 0.015 0 0
The phototransduction cascade R-HSA-2514856 9.666147e-01 0.015 0 0
SARS-CoV Infections R-HSA-9679506 9.666702e-01 0.015 0 0
Platelet degranulation R-HSA-114608 9.672647e-01 0.014 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 9.683907e-01 0.014 0 0
Activation of ATR in response to replication stress R-HSA-176187 9.684255e-01 0.014 0 0
Recycling of bile acids and salts R-HSA-159418 9.684255e-01 0.014 0 0
PPARA activates gene expression R-HSA-1989781 9.688085e-01 0.014 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 9.690158e-01 0.014 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.690158e-01 0.014 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 9.704356e-01 0.013 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 9.711059e-01 0.013 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.711059e-01 0.013 0 0
Heme degradation R-HSA-189483 9.711059e-01 0.013 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.723548e-01 0.012 0 0
Cap-dependent Translation Initiation R-HSA-72737 9.727870e-01 0.012 0 0
Eukaryotic Translation Initiation R-HSA-72613 9.727870e-01 0.012 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.733282e-01 0.012 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 9.735588e-01 0.012 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.735588e-01 0.012 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 9.735588e-01 0.012 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.735588e-01 0.012 0 0
Signaling by NOTCH2 R-HSA-1980145 9.735588e-01 0.012 0 0
RA biosynthesis pathway R-HSA-5365859 9.735588e-01 0.012 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.735588e-01 0.012 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.741555e-01 0.011 0 0
Interferon gamma signaling R-HSA-877300 9.742135e-01 0.011 0 0
Neurotransmitter release cycle R-HSA-112310 9.751969e-01 0.011 0 0
G alpha (z) signalling events R-HSA-418597 9.752610e-01 0.011 0 0
RSV-host interactions R-HSA-9833110 9.757455e-01 0.011 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.758037e-01 0.011 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.758037e-01 0.011 0 0
PERK regulates gene expression R-HSA-381042 9.758037e-01 0.011 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.778580e-01 0.010 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.778580e-01 0.010 0 0
GPVI-mediated activation cascade R-HSA-114604 9.778580e-01 0.010 0 0
Dectin-2 family R-HSA-5621480 9.787284e-01 0.009 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 9.789126e-01 0.009 0 0
Voltage gated Potassium channels R-HSA-1296072 9.797381e-01 0.009 0 0
Degradation of AXIN R-HSA-4641257 9.797381e-01 0.009 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.797381e-01 0.009 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.797381e-01 0.009 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 9.808266e-01 0.008 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 9.808266e-01 0.008 0 0
Stimuli-sensing channels R-HSA-2672351 9.808266e-01 0.008 0 0
tRNA processing in the mitochondrion R-HSA-6785470 9.814586e-01 0.008 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.814586e-01 0.008 0 0
Cholesterol biosynthesis R-HSA-191273 9.816070e-01 0.008 0 0
RNA Polymerase I Transcription R-HSA-73864 9.816070e-01 0.008 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.817228e-01 0.008 0 0
Interleukin-1 family signaling R-HSA-446652 9.828750e-01 0.008 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.830332e-01 0.007 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.830332e-01 0.007 0 0
RAS processing R-HSA-9648002 9.830332e-01 0.007 0 0
Pentose phosphate pathway R-HSA-71336 9.830332e-01 0.007 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.830332e-01 0.007 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.830623e-01 0.007 0 0
Signaling by Hedgehog R-HSA-5358351 9.834737e-01 0.007 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 9.839705e-01 0.007 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.843063e-01 0.007 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 9.844741e-01 0.007 0 0
Diseases of Immune System R-HSA-5260271 9.844741e-01 0.007 0 0
Attenuation phase R-HSA-3371568 9.844741e-01 0.007 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.844741e-01 0.007 0 0
rRNA processing in the mitochondrion R-HSA-8868766 9.844741e-01 0.007 0 0
Tryptophan catabolism R-HSA-71240 9.844741e-01 0.007 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 9.848964e-01 0.007 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 9.848964e-01 0.007 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.850365e-01 0.007 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.857927e-01 0.006 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.857927e-01 0.006 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.857927e-01 0.006 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.857927e-01 0.006 0 0
Maturation of spike protein R-HSA-9694548 9.857927e-01 0.006 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.857927e-01 0.006 0 0
G2/M Checkpoints R-HSA-69481 9.860929e-01 0.006 0 0
Peptide ligand-binding receptors R-HSA-375276 9.862011e-01 0.006 0 0
G alpha (s) signalling events R-HSA-418555 9.864104e-01 0.006 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.865894e-01 0.006 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.868406e-01 0.006 0 0
Intra-Golgi traffic R-HSA-6811438 9.869994e-01 0.006 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 9.869994e-01 0.006 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.869994e-01 0.006 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.869994e-01 0.006 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.873909e-01 0.006 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.876631e-01 0.005 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.881037e-01 0.005 0 0
Depyrimidination R-HSA-73928 9.881037e-01 0.005 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 9.881037e-01 0.005 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.881037e-01 0.005 0 0
ABC-family proteins mediated transport R-HSA-382556 9.884365e-01 0.005 0 0
Defective pyroptosis R-HSA-9710421 9.891142e-01 0.005 0 0
Defensins R-HSA-1461973 9.891142e-01 0.005 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.891142e-01 0.005 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.891142e-01 0.005 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.893076e-01 0.005 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.894396e-01 0.005 0 0
Neddylation R-HSA-8951664 9.895438e-01 0.005 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.900390e-01 0.004 0 0
Proteasome assembly R-HSA-9907900 9.900390e-01 0.004 0 0
Amine ligand-binding receptors R-HSA-375280 9.900390e-01 0.004 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.900390e-01 0.004 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.900390e-01 0.004 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.901019e-01 0.004 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.901019e-01 0.004 0 0
O-linked glycosylation of mucins R-HSA-913709 9.908384e-01 0.004 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.908852e-01 0.004 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.908852e-01 0.004 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.908852e-01 0.004 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.908852e-01 0.004 0 0
Somitogenesis R-HSA-9824272 9.908852e-01 0.004 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 9.910918e-01 0.004 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.916596e-01 0.004 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.916596e-01 0.004 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.916596e-01 0.004 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.923682e-01 0.003 0 0
Synthesis of PC R-HSA-1483191 9.923682e-01 0.003 0 0
Downstream TCR signaling R-HSA-202424 9.925786e-01 0.003 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.927411e-01 0.003 0 0
Hedgehog 'on' state R-HSA-5632684 9.927411e-01 0.003 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.928007e-01 0.003 0 0
Gluconeogenesis R-HSA-70263 9.930167e-01 0.003 0 0
Immune System R-HSA-168256 9.931493e-01 0.003 0 0
Synthesis of DNA R-HSA-69239 9.931575e-01 0.003 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.936101e-01 0.003 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.936101e-01 0.003 0 0
Hemostasis R-HSA-109582 9.937789e-01 0.003 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.940063e-01 0.003 0 0
DNA Replication Pre-Initiation R-HSA-69002 9.940095e-01 0.003 0 0
Azathioprine ADME R-HSA-9748787 9.941531e-01 0.003 0 0
Signaling by NOTCH4 R-HSA-9013694 9.942553e-01 0.003 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.943962e-01 0.002 0 0
Assembly of the pre-replicative complex R-HSA-68867 9.944200e-01 0.002 0 0
Complex IV assembly R-HSA-9864848 9.946500e-01 0.002 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.946500e-01 0.002 0 0
Leishmania infection R-HSA-9658195 9.947920e-01 0.002 0 0
Parasitic Infection Pathways R-HSA-9824443 9.947920e-01 0.002 0 0
Collagen formation R-HSA-1474290 9.948060e-01 0.002 0 0
Cellular response to starvation R-HSA-9711097 9.948946e-01 0.002 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.950988e-01 0.002 0 0
Orc1 removal from chromatin R-HSA-68949 9.951047e-01 0.002 0 0
Post-translational protein modification R-HSA-597592 9.952806e-01 0.002 1 0
Nucleotide biosynthesis R-HSA-8956320 9.955208e-01 0.002 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.959015e-01 0.002 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.959959e-01 0.002 0 0
Viral Infection Pathways R-HSA-9824446 9.962934e-01 0.002 0 0
Cardiac conduction R-HSA-5576891 9.963915e-01 0.002 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.965035e-01 0.002 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.965687e-01 0.001 0 0
Synthesis of PA R-HSA-1483166 9.968604e-01 0.001 0 0
Peptide hormone metabolism R-HSA-2980736 9.969487e-01 0.001 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.971702e-01 0.001 0 0
Phospholipid metabolism R-HSA-1483257 9.972882e-01 0.001 0 0
Protein localization R-HSA-9609507 9.975470e-01 0.001 0 0
Glutathione conjugation R-HSA-156590 9.975951e-01 0.001 0 0
Metabolism of polyamines R-HSA-351202 9.975951e-01 0.001 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 9.976232e-01 0.001 1 1
C-type lectin receptors (CLRs) R-HSA-5621481 9.977613e-01 0.001 0 0
Endogenous sterols R-HSA-211976 9.977996e-01 0.001 0 0
Nucleotide salvage R-HSA-8956321 9.977996e-01 0.001 0 0
Collagen degradation R-HSA-1442490 9.977996e-01 0.001 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.979399e-01 0.001 0 0
Mitochondrial protein import R-HSA-1268020 9.979867e-01 0.001 0 0
Signaling by PDGF R-HSA-186797 9.979867e-01 0.001 0 0
Platelet homeostasis R-HSA-418346 9.981243e-01 0.001 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 9.981580e-01 0.001 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.982059e-01 0.001 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.982576e-01 0.001 0 0
ER-Phagosome pathway R-HSA-1236974 9.983779e-01 0.001 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.983817e-01 0.001 0 0
Base Excision Repair R-HSA-73884 9.985024e-01 0.001 0 0
Antimicrobial peptides R-HSA-6803157 9.987042e-01 0.001 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.987239e-01 0.001 0 0
G alpha (q) signalling events R-HSA-416476 9.987834e-01 0.001 0 0
Regulated Necrosis R-HSA-5218859 9.988190e-01 0.001 0 0
GPCR downstream signalling R-HSA-388396 9.989679e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.990114e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.990399e-01 0.000 1 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.990743e-01 0.000 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 9.990743e-01 0.000 0 0
ECM proteoglycans R-HSA-3000178 9.990955e-01 0.000 0 0
Metal ion assimilation from the host R-HSA-9638482 9.990955e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.990955e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.991160e-01 0.000 0 0
Formation of a pool of free 40S subunits R-HSA-72689 9.991458e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.991725e-01 0.000 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 9.992079e-01 0.000 1 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.992119e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.992429e-01 0.000 0 0
DNA Replication R-HSA-69306 9.992588e-01 0.000 0 0
Keratinization R-HSA-6805567 9.992679e-01 0.000 0 0
Transport of vitamins, nucleosides, and related molecules R-HSA-425397 9.993073e-01 0.000 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.993073e-01 0.000 0 0
Iron uptake and transport R-HSA-917937 9.993663e-01 0.000 0 0
SARS-CoV-1 Infection R-HSA-9678108 9.994342e-01 0.000 0 0
Translation of Structural Proteins R-HSA-9694635 9.994696e-01 0.000 0 0
ABC transporter disorders R-HSA-5619084 9.995147e-01 0.000 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.995560e-01 0.000 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 9.995938e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.996544e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.997155e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.997896e-01 0.000 0 0
Pyruvate metabolism R-HSA-70268 9.998007e-01 0.000 0 0
Peptide chain elongation R-HSA-156902 9.998177e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.998474e-01 0.000 0 0
rRNA processing R-HSA-72312 9.998533e-01 0.000 1 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.998604e-01 0.000 0 0
Interferon alpha/beta signaling R-HSA-909733 9.998683e-01 0.000 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.998832e-01 0.000 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.998832e-01 0.000 0 0
Ribosome-associated quality control R-HSA-9948299 9.998856e-01 0.000 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.998931e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.998931e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999167e-01 0.000 0 0
Eukaryotic Translation Termination R-HSA-72764 9.999182e-01 0.000 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.999182e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999244e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999252e-01 0.000 0 0
Potassium Channels R-HSA-1296071 9.999252e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999374e-01 0.000 0 0
Selenocysteine synthesis R-HSA-2408557 9.999521e-01 0.000 0 0
Viral mRNA Translation R-HSA-192823 9.999599e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999599e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.999725e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999785e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999793e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999833e-01 0.000 0 0
Selenoamino acid metabolism R-HSA-2408522 9.999862e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999918e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999933e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999938e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999954e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999956e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.999961e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.999964e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999972e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999972e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999978e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.999987e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.999988e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999989e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999990e-01 0.000 0 0
Translation R-HSA-72766 9.999994e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999996e-01 0.000 0 0
Disease R-HSA-1643685 9.999997e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999997e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999997e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999999e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999999e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.999999e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 1.000000e+00 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 1.000000e+00 0.000 0 0
Respiratory electron transport R-HSA-611105 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 0.000 1 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 2.220446e-16 15.654 0 0
HSF1-dependent transactivation R-HSA-3371571 2.553513e-15 14.593 0 0
Attenuation phase R-HSA-3371568 1.987299e-14 13.702 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 6.283862e-14 13.202 0 0
Metabolism of RNA R-HSA-8953854 1.999512e-13 12.699 1 0
HSF1 activation R-HSA-3371511 9.916512e-13 12.004 0 0
Cell Cycle R-HSA-1640170 4.354517e-12 11.361 1 0
Cellular responses to stimuli R-HSA-8953897 4.603540e-12 11.337 0 0
M Phase R-HSA-68886 6.055645e-11 10.218 1 0
Cellular responses to stress R-HSA-2262752 6.078893e-11 10.216 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.229874e-10 9.652 0 0
Cell Cycle, Mitotic R-HSA-69278 9.350242e-10 9.029 1 0
mRNA Splicing R-HSA-72172 1.155862e-09 8.937 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.848000e-09 8.733 0 0
Mitotic Anaphase R-HSA-68882 2.269932e-09 8.644 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.601542e-09 8.585 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 8.006990e-09 8.097 0 0
Separation of Sister Chromatids R-HSA-2467813 9.714522e-09 8.013 0 0
Mitotic Prometaphase R-HSA-68877 8.548666e-08 7.068 1 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.417194e-07 6.849 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.003728e-07 6.698 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.035923e-07 6.518 0 0
Apoptotic execution phase R-HSA-75153 3.002041e-07 6.523 0 0
Cell Cycle Checkpoints R-HSA-69620 3.450429e-07 6.462 0 0
Apoptosis R-HSA-109581 4.238502e-07 6.373 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 8.906416e-07 6.050 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.955925e-06 5.709 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 2.804940e-06 5.552 0 0
Chaperone Mediated Autophagy R-HSA-9613829 5.688609e-06 5.245 0 0
mRNA 3'-end processing R-HSA-72187 5.420235e-06 5.266 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 5.587979e-06 5.253 0 0
Programmed Cell Death R-HSA-5357801 5.519527e-06 5.258 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.237770e-05 4.907 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.583188e-05 4.800 0 0
Regulation of CDH1 Function R-HSA-9764561 1.556562e-05 4.808 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.510697e-05 4.821 0 0
Signaling by ALK in cancer R-HSA-9700206 1.510697e-05 4.821 0 0
G2/M Checkpoints R-HSA-69481 1.718531e-05 4.765 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.837115e-05 4.736 0 0
Adherens junctions interactions R-HSA-418990 1.978991e-05 4.704 0 0
Signaling by Hippo R-HSA-2028269 2.296256e-05 4.639 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.314220e-05 4.636 1 0
Cap-dependent Translation Initiation R-HSA-72737 2.486137e-05 4.604 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.486137e-05 4.604 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 2.574897e-05 4.589 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 2.574897e-05 4.589 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 2.818792e-05 4.550 0 0
PKR-mediated signaling R-HSA-9833482 2.810308e-05 4.551 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 2.707674e-05 4.567 0 0
Cell-Cell communication R-HSA-1500931 2.867466e-05 4.543 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 3.350731e-05 4.475 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 4.259555e-05 4.371 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 4.302273e-05 4.366 1 1
Cell junction organization R-HSA-446728 4.382350e-05 4.358 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 4.400416e-05 4.357 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 4.643884e-05 4.333 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 4.944671e-05 4.306 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.988018e-05 4.302 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 5.242948e-05 4.280 1 1
Aggrephagy R-HSA-9646399 6.207896e-05 4.207 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 6.368203e-05 4.196 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 8.327816e-05 4.079 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 8.327816e-05 4.079 0 0
Nervous system development R-HSA-9675108 8.934240e-05 4.049 0 0
Translation initiation complex formation R-HSA-72649 1.009970e-04 3.996 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.068736e-04 3.971 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.081939e-04 3.966 1 1
HIV Life Cycle R-HSA-162587 1.196412e-04 3.922 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.262708e-04 3.899 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 1.274250e-04 3.895 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.349949e-04 3.870 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.422936e-04 3.847 1 1
Regulation of MECP2 expression and activity R-HSA-9022692 1.510360e-04 3.821 0 0
Cell-cell junction organization R-HSA-421270 1.568028e-04 3.805 0 0
Axon guidance R-HSA-422475 1.570260e-04 3.804 0 0
Gene expression (Transcription) R-HSA-74160 1.600966e-04 3.796 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.710592e-04 3.767 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.856976e-04 3.731 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 2.061782e-04 3.686 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.066914e-04 3.685 0 0
Influenza Infection R-HSA-168255 2.196135e-04 3.658 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 2.277592e-04 3.643 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.322596e-04 3.634 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 2.470889e-04 3.607 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.384845e-04 3.623 0 0
SARS-CoV-1-host interactions R-HSA-9692914 2.347404e-04 3.629 0 0
Chromatin organization R-HSA-4839726 2.605019e-04 3.584 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 2.819371e-04 3.550 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.970453e-04 3.527 0 0
Selective autophagy R-HSA-9663891 2.896682e-04 3.538 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.959370e-04 3.529 0 0
ISG15 antiviral mechanism R-HSA-1169408 3.177754e-04 3.498 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 3.239564e-04 3.490 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 3.258576e-04 3.487 0 0
Signaling by RAF1 mutants R-HSA-9656223 3.367501e-04 3.473 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 3.525267e-04 3.453 0 0
Regulation of TP53 Degradation R-HSA-6804757 3.611139e-04 3.442 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 3.727117e-04 3.429 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 3.841184e-04 3.416 0 0
G2/M Transition R-HSA-69275 3.995642e-04 3.398 1 0
MITF-M-regulated melanocyte development R-HSA-9730414 4.703088e-04 3.328 0 0
Mitotic G2-G2/M phases R-HSA-453274 4.707358e-04 3.327 1 0
rRNA processing R-HSA-72312 5.215574e-04 3.283 1 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 5.364875e-04 3.270 0 0
Eukaryotic Translation Elongation R-HSA-156842 5.387345e-04 3.269 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 5.564960e-04 3.255 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 5.731326e-04 3.242 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 5.858940e-04 3.232 0 0
Mitotic Spindle Checkpoint R-HSA-69618 6.230849e-04 3.205 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 5.956193e-04 3.225 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 6.480815e-04 3.188 0 0
Late Phase of HIV Life Cycle R-HSA-162599 6.527442e-04 3.185 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 6.571296e-04 3.182 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 6.774589e-04 3.169 0 0
AURKA Activation by TPX2 R-HSA-8854518 6.862559e-04 3.164 1 1
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 7.029693e-04 3.153 0 0
Clathrin-mediated endocytosis R-HSA-8856828 7.145889e-04 3.146 0 0
Signaling downstream of RAS mutants R-HSA-9649948 8.177231e-04 3.087 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 8.177231e-04 3.087 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 8.177231e-04 3.087 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 8.177231e-04 3.087 0 0
DNA Double Strand Break Response R-HSA-5693606 7.884058e-04 3.103 0 0
Signaling by RAS mutants R-HSA-6802949 8.177231e-04 3.087 0 0
Smooth Muscle Contraction R-HSA-445355 8.278540e-04 3.082 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 8.527937e-04 3.069 0 0
Protein ubiquitination R-HSA-8852135 8.541121e-04 3.068 0 0
Nuclear import of Rev protein R-HSA-180746 8.563591e-04 3.067 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 9.194327e-04 3.036 0 0
Recycling pathway of L1 R-HSA-437239 9.629602e-04 3.016 0 0
Pexophagy R-HSA-9664873 9.096737e-04 3.041 0 0
Interleukin-12 signaling R-HSA-9020591 9.701694e-04 3.013 0 0
Cilium Assembly R-HSA-5617833 1.085103e-03 2.965 1 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.105610e-03 2.956 0 0
S Phase R-HSA-69242 1.106780e-03 2.956 0 0
Chromatin modifying enzymes R-HSA-3247509 1.119853e-03 2.951 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.121232e-03 2.950 0 0
Activation of BH3-only proteins R-HSA-114452 1.121232e-03 2.950 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.242706e-03 2.906 1 1
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.242706e-03 2.906 1 1
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.287263e-03 2.890 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.287263e-03 2.890 0 0
HIV Infection R-HSA-162906 1.283821e-03 2.891 0 0
Mitotic Prophase R-HSA-68875 1.269293e-03 2.896 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.175845e-03 2.930 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.279805e-03 2.893 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.279805e-03 2.893 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.309490e-03 2.883 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.323219e-03 2.878 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.323219e-03 2.878 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.370068e-03 2.863 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.370068e-03 2.863 0 0
Regulation of TP53 Activity R-HSA-5633007 1.466512e-03 2.834 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.490860e-03 2.827 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.490860e-03 2.827 0 0
Post NMDA receptor activation events R-HSA-438064 1.614343e-03 2.792 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.673478e-03 2.776 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 1.706906e-03 2.768 0 0
Interleukin-12 family signaling R-HSA-447115 1.614343e-03 2.792 0 0
Membrane Trafficking R-HSA-199991 1.744689e-03 2.758 1 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 1.774483e-03 2.751 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 1.866822e-03 2.729 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.831674e-03 2.737 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.831674e-03 2.737 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 2.002479e-03 2.698 0 0
snRNP Assembly R-HSA-191859 1.959839e-03 2.708 0 0
Metabolism of non-coding RNA R-HSA-194441 1.959839e-03 2.708 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.866822e-03 2.729 0 0
NF-kB is activated and signals survival R-HSA-209560 1.866822e-03 2.729 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.932736e-03 2.714 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.961824e-03 2.707 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 2.002479e-03 2.698 0 0
Death Receptor Signaling R-HSA-73887 1.812734e-03 2.742 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.005207e-03 2.698 0 0
Stabilization of p53 R-HSA-69541 2.096717e-03 2.678 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 2.305307e-03 2.637 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 2.305307e-03 2.637 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.305307e-03 2.637 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 2.396983e-03 2.620 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 2.467137e-03 2.608 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 2.571434e-03 2.590 0 0
Formation of annular gap junctions R-HSA-196025 2.571434e-03 2.590 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 2.571434e-03 2.590 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 2.673768e-03 2.573 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.761827e-03 2.559 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 2.869987e-03 2.542 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.886409e-03 2.540 0 0
tRNA processing in the nucleus R-HSA-6784531 2.888874e-03 2.539 0 0
EPH-Ephrin signaling R-HSA-2682334 3.044423e-03 2.516 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 3.441896e-03 2.463 0 0
Late endosomal microautophagy R-HSA-9615710 3.227776e-03 2.491 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.372375e-03 2.472 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 3.522430e-03 2.453 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 3.407488e-03 2.468 0 0
Signaling by EGFR R-HSA-177929 3.522430e-03 2.453 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 3.371556e-03 2.472 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 3.268947e-03 2.486 0 0
Transport of connexons to the plasma membrane R-HSA-190872 3.670824e-03 2.435 0 0
Gap junction degradation R-HSA-190873 3.712480e-03 2.430 0 0
Unwinding of DNA R-HSA-176974 3.712480e-03 2.430 0 0
Gap junction trafficking and regulation R-HSA-157858 3.744105e-03 2.427 0 0
Chaperonin-mediated protein folding R-HSA-390466 3.774347e-03 2.423 0 0
Host Interactions of HIV factors R-HSA-162909 3.813830e-03 2.419 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.965870e-03 2.402 0 0
DNA Repair R-HSA-73894 3.990623e-03 2.399 0 0
Autophagy R-HSA-9612973 4.107768e-03 2.386 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 4.220546e-03 2.375 1 1
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 4.318172e-03 2.365 0 0
SARS-CoV-2-host interactions R-HSA-9705683 4.373116e-03 2.359 0 0
Formation of a pool of free 40S subunits R-HSA-72689 4.489849e-03 2.348 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.524783e-03 2.344 0 0
EGFR downregulation R-HSA-182971 4.604336e-03 2.337 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 4.607489e-03 2.337 0 0
Translesion Synthesis by POLH R-HSA-110320 4.607489e-03 2.337 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.726460e-03 2.325 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 4.920381e-03 2.308 0 0
Maturation of protein E R-HSA-9683683 4.920381e-03 2.308 0 0
Maturation of protein E R-HSA-9694493 4.920381e-03 2.308 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 5.177139e-03 2.286 0 0
Folding of actin by CCT/TriC R-HSA-390450 5.177139e-03 2.286 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 5.548473e-03 2.256 0 0
Centrosome maturation R-HSA-380287 5.236148e-03 2.281 1 0
Signaling by ERBB2 R-HSA-1227986 5.751072e-03 2.240 0 0
Josephin domain DUBs R-HSA-5689877 5.177139e-03 2.286 0 0
Negative regulation of MET activity R-HSA-6807004 5.713875e-03 2.243 0 0
Gap junction trafficking R-HSA-190828 5.189581e-03 2.285 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 5.839825e-03 2.234 0 0
p75NTR signals via NF-kB R-HSA-193639 5.839825e-03 2.234 0 0
Spry regulation of FGF signaling R-HSA-1295596 5.839825e-03 2.234 0 0
Fanconi Anemia Pathway R-HSA-6783310 5.945806e-03 2.226 0 0
Signaling by EGFR in Cancer R-HSA-1643713 6.272030e-03 2.203 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 6.283542e-03 2.202 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 6.703382e-03 2.174 0 0
Protein folding R-HSA-391251 6.720066e-03 2.173 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 6.786052e-03 2.168 0 0
Epigenetic regulation of gene expression R-HSA-212165 6.988749e-03 2.156 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 7.007735e-03 2.154 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 7.009686e-03 2.154 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 7.477444e-03 2.126 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 7.716397e-03 2.113 0 0
PTEN Regulation R-HSA-6807070 7.721596e-03 2.112 0 0
Signaling by NOTCH3 R-HSA-9012852 7.983414e-03 2.098 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 8.944354e-03 2.048 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 8.944354e-03 2.048 0 0
Disorders of Developmental Biology R-HSA-9675151 9.272557e-03 2.033 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.557535e-03 2.020 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 9.846336e-03 2.007 0 0
Regulation of endogenous retroelements R-HSA-9842860 8.351996e-03 2.078 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 9.272557e-03 2.033 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 9.252759e-03 2.034 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 8.688856e-03 2.061 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 9.872251e-03 2.006 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 9.872251e-03 2.006 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 8.870001e-03 2.052 0 0
Degradation of CDH1 R-HSA-9766229 9.872251e-03 2.006 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.797299e-03 2.009 0 0
Macroautophagy R-HSA-1632852 8.881308e-03 2.052 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 9.846336e-03 2.007 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 8.274600e-03 2.082 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.004347e-02 1.998 0 0
Oncogene Induced Senescence R-HSA-2559585 1.004347e-02 1.998 0 0
mTORC1-mediated signalling R-HSA-166208 1.022931e-02 1.990 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 1.022931e-02 1.990 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.037260e-02 1.984 0 0
Regulation of PTEN localization R-HSA-8948747 1.054790e-02 1.977 0 0
Dual incision in TC-NER R-HSA-6782135 1.118448e-02 1.951 0 0
Nucleotide Excision Repair R-HSA-5696398 1.154683e-02 1.938 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 1.155120e-02 1.937 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.187910e-02 1.925 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.191373e-02 1.924 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.194658e-02 1.923 0 0
VLDLR internalisation and degradation R-HSA-8866427 1.194658e-02 1.923 0 0
p75NTR recruits signalling complexes R-HSA-209543 1.194658e-02 1.923 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 1.210305e-02 1.917 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.219241e-02 1.914 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 1.220191e-02 1.914 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 1.253746e-02 1.902 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.322192e-02 1.879 0 0
Degradation of DVL R-HSA-4641258 1.322192e-02 1.879 0 0
Ribosome-associated quality control R-HSA-9948299 1.339848e-02 1.873 0 0
Synthesis of DNA R-HSA-69239 1.347214e-02 1.871 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 1.364739e-02 1.865 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.381420e-02 1.860 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.393919e-02 1.856 0 0
Orc1 removal from chromatin R-HSA-68949 1.393919e-02 1.856 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.394742e-02 1.856 0 0
Hedgehog 'off' state R-HSA-5610787 1.436381e-02 1.843 0 0
Glycolysis R-HSA-70171 1.436381e-02 1.843 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 1.447562e-02 1.839 0 0
Modulation by Mtb of host immune system R-HSA-9637628 1.447562e-02 1.839 0 0
Signaling by ROBO receptors R-HSA-376176 1.449707e-02 1.839 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.512830e-02 1.820 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.883147e-02 1.725 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 1.739269e-02 1.760 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 1.554265e-02 1.808 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.554265e-02 1.808 0 0
DNA strand elongation R-HSA-69190 1.618603e-02 1.791 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.631714e-02 1.787 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 1.883147e-02 1.725 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.512830e-02 1.820 0 0
Homology Directed Repair R-HSA-5693538 1.799582e-02 1.745 0 0
L1CAM interactions R-HSA-373760 1.565900e-02 1.805 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 1.883147e-02 1.725 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 1.856327e-02 1.731 0 0
Regulation of TNFR1 signaling R-HSA-5357905 1.739269e-02 1.760 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.550904e-02 1.809 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.529381e-02 1.815 0 0
Signal Transduction R-HSA-162582 1.584343e-02 1.800 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 1.709141e-02 1.767 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.512830e-02 1.820 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 1.550904e-02 1.809 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.617747e-02 1.791 0 0
RNA Polymerase II Transcription R-HSA-73857 1.893488e-02 1.723 0 0
Peptide chain elongation R-HSA-156902 1.905347e-02 1.720 0 0
ALK mutants bind TKIs R-HSA-9700645 1.922136e-02 1.716 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 1.922136e-02 1.716 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.922136e-02 1.716 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 1.943994e-02 1.711 0 0
ESR-mediated signaling R-HSA-8939211 1.952254e-02 1.709 0 0
Metalloprotease DUBs R-HSA-5689901 1.969490e-02 1.706 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 2.005646e-02 1.698 0 0
Processing of DNA double-strand break ends R-HSA-5693607 2.022302e-02 1.694 0 0
Translation R-HSA-72766 2.056918e-02 1.687 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 2.118019e-02 1.674 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.118548e-02 1.674 0 0
Estrogen-dependent gene expression R-HSA-9018519 2.124831e-02 1.673 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.165826e-02 1.664 0 0
IRS activation R-HSA-74713 2.172338e-02 1.663 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 2.172338e-02 1.663 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 2.172832e-02 1.663 0 0
PKMTs methylate histone lysines R-HSA-3214841 2.172832e-02 1.663 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 2.225834e-02 1.653 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 2.225834e-02 1.653 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.244068e-02 1.649 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.278631e-02 1.642 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 2.308559e-02 1.637 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 2.308559e-02 1.637 0 0
Translesion synthesis by REV1 R-HSA-110312 2.308559e-02 1.637 0 0
Protein methylation R-HSA-8876725 2.308559e-02 1.637 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 2.308559e-02 1.637 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.308559e-02 1.637 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 2.328285e-02 1.633 0 0
Signaling by NOTCH4 R-HSA-9013694 2.328285e-02 1.633 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.370236e-02 1.625 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.401569e-02 1.620 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 2.404803e-02 1.619 0 0
Dual Incision in GG-NER R-HSA-5696400 2.404803e-02 1.619 0 0
Calnexin/calreticulin cycle R-HSA-901042 2.404803e-02 1.619 0 0
DNA Damage Bypass R-HSA-73893 2.405491e-02 1.619 0 0
MAP2K and MAPK activation R-HSA-5674135 2.435735e-02 1.613 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.482672e-02 1.605 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.522137e-02 1.598 0 0
Manipulation of host energy metabolism R-HSA-9636667 2.670642e-02 1.573 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 3.052002e-02 1.515 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 2.791583e-02 1.554 0 0
Translesion synthesis by POLI R-HSA-5656121 2.791583e-02 1.554 0 0
Translesion synthesis by POLK R-HSA-5655862 3.334278e-02 1.477 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.776737e-02 1.556 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.776737e-02 1.556 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.776737e-02 1.556 0 0
Notch-HLH transcription pathway R-HSA-350054 3.226751e-02 1.491 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 2.994059e-02 1.524 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 3.057847e-02 1.515 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 3.238383e-02 1.490 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 3.238383e-02 1.490 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 3.087949e-02 1.510 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 2.576912e-02 1.589 0 0
RNA Polymerase III Transcription R-HSA-74158 3.057847e-02 1.515 0 0
Ca-dependent events R-HSA-111996 2.720492e-02 1.565 0 0
CaM pathway R-HSA-111997 3.057847e-02 1.515 0 0
Calmodulin induced events R-HSA-111933 3.057847e-02 1.515 0 0
MTOR signalling R-HSA-165159 2.720492e-02 1.565 0 0
EPHB-mediated forward signaling R-HSA-3928662 3.358756e-02 1.474 0 0
PCP/CE pathway R-HSA-4086400 3.224207e-02 1.492 0 0
Breakdown of the nuclear lamina R-HSA-352238 2.670642e-02 1.573 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 2.994059e-02 1.524 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 2.619723e-02 1.582 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 3.027911e-02 1.519 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 2.714428e-02 1.566 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.087949e-02 1.510 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 3.334278e-02 1.477 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 3.426033e-02 1.465 0 0
Hedgehog ligand biogenesis R-HSA-5358346 2.941109e-02 1.531 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 3.226751e-02 1.491 0 0
Interleukin-1 signaling R-HSA-9020702 2.981044e-02 1.526 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.776737e-02 1.556 0 0
Negative regulation of FLT3 R-HSA-9706369 2.791583e-02 1.554 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 3.052002e-02 1.515 0 0
IRE1alpha activates chaperones R-HSA-381070 2.595261e-02 1.586 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 3.449634e-02 1.462 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 3.455795e-02 1.461 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 3.556128e-02 1.449 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 3.556128e-02 1.449 0 0
Meiotic synapsis R-HSA-1221632 3.556128e-02 1.449 0 0
Regulation of PTEN stability and activity R-HSA-8948751 3.556128e-02 1.449 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 3.568722e-02 1.447 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 3.568722e-02 1.447 0 0
Interferon Signaling R-HSA-913531 3.579009e-02 1.446 0 0
Response of endothelial cells to shear stress R-HSA-9860931 3.641271e-02 1.439 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 3.694568e-02 1.432 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 3.713739e-02 1.430 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 3.713739e-02 1.430 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 3.721650e-02 1.429 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.737446e-02 1.427 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 3.847025e-02 1.415 0 0
Budding and maturation of HIV virion R-HSA-162588 3.847025e-02 1.415 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 3.847025e-02 1.415 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 3.894916e-02 1.410 0 0
Glycogen storage diseases R-HSA-3229121 3.938236e-02 1.405 0 0
SARS-CoV Infections R-HSA-9679506 3.950962e-02 1.403 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 3.997476e-02 1.398 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 4.093513e-02 1.388 0 0
Signaling by Hedgehog R-HSA-5358351 4.121983e-02 1.385 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 4.225119e-02 1.374 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 4.255282e-02 1.371 0 0
Vesicle-mediated transport R-HSA-5653656 4.411846e-02 1.355 1 0
SARS-CoV-2 Infection R-HSA-9694516 4.472638e-02 1.349 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.496658e-02 1.347 0 0
Regulation of TP53 Expression R-HSA-6804754 4.496658e-02 1.347 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.496658e-02 1.347 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.496658e-02 1.347 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.496658e-02 1.347 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.496658e-02 1.347 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.496658e-02 1.347 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.496658e-02 1.347 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.496658e-02 1.347 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.496658e-02 1.347 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.496658e-02 1.347 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.496658e-02 1.347 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.498675e-02 1.347 0 0
Cytokine Signaling in Immune system R-HSA-1280215 4.591667e-02 1.338 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 4.637716e-02 1.334 0 0
TNF signaling R-HSA-75893 4.637716e-02 1.334 0 0
NRAGE signals death through JNK R-HSA-193648 4.637716e-02 1.334 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 4.678581e-02 1.330 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.703952e-02 1.328 0 0
Disorders of Nervous System Development R-HSA-9697154 4.703952e-02 1.328 0 0
Pervasive developmental disorders R-HSA-9005895 4.703952e-02 1.328 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 4.703952e-02 1.328 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.703952e-02 1.328 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 4.703952e-02 1.328 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 4.703952e-02 1.328 0 0
IRAK1 recruits IKK complex R-HSA-937039 4.703952e-02 1.328 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 4.703952e-02 1.328 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 4.707116e-02 1.327 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 4.707116e-02 1.327 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 4.845308e-02 1.315 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 4.845308e-02 1.315 0 0
Regulation of necroptotic cell death R-HSA-5675482 4.845308e-02 1.315 0 0
Activation of ATR in response to replication stress R-HSA-176187 4.845308e-02 1.315 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 4.845308e-02 1.315 0 0
Long-term potentiation R-HSA-9620244 4.850396e-02 1.314 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 4.909707e-02 1.309 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 6.657043e-02 1.177 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 6.657043e-02 1.177 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 6.657043e-02 1.177 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 5.285124e-02 1.277 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 5.285124e-02 1.277 0 0
Recycling of eIF2:GDP R-HSA-72731 5.285124e-02 1.277 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 6.626666e-02 1.179 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 5.626704e-02 1.250 0 0
Regulation of signaling by CBL R-HSA-912631 5.333957e-02 1.273 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 5.333957e-02 1.273 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 5.485774e-02 1.261 0 0
HIV elongation arrest and recovery R-HSA-167287 6.900493e-02 1.161 0 0
Pausing and recovery of HIV elongation R-HSA-167290 6.900493e-02 1.161 0 0
Striated Muscle Contraction R-HSA-390522 5.400750e-02 1.268 0 0
RAF activation R-HSA-5673000 5.994392e-02 1.222 0 0
Signaling by NOTCH2 R-HSA-1980145 5.994392e-02 1.222 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 5.195213e-02 1.284 0 0
UCH proteinases R-HSA-5689603 5.431929e-02 1.265 0 0
Deubiquitination R-HSA-5688426 6.292696e-02 1.201 0 0
Cellular response to starvation R-HSA-9711097 7.120527e-02 1.147 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 5.485774e-02 1.261 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 5.195213e-02 1.284 0 0
Myogenesis R-HSA-525793 5.485774e-02 1.261 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 5.387225e-02 1.269 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 6.396289e-02 1.194 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 6.396289e-02 1.194 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 6.396289e-02 1.194 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 6.396289e-02 1.194 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 5.195213e-02 1.284 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 6.626540e-02 1.179 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 6.626540e-02 1.179 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 5.714719e-02 1.243 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 6.266010e-02 1.203 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 5.477937e-02 1.261 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 7.244763e-02 1.140 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 6.169092e-02 1.210 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 5.714719e-02 1.243 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 5.714719e-02 1.243 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 6.626666e-02 1.179 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 5.016502e-02 1.300 0 0
Gap junction assembly R-HSA-190861 5.994392e-02 1.222 0 0
Glycogen synthesis R-HSA-3322077 6.126571e-02 1.213 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 5.195213e-02 1.284 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 6.900493e-02 1.161 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 7.297349e-02 1.137 0 0
Signaling by VEGF R-HSA-194138 5.205731e-02 1.284 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 6.396289e-02 1.194 0 0
Cellular Senescence R-HSA-2559583 5.191612e-02 1.285 0 0
Platelet degranulation R-HSA-114608 5.791054e-02 1.237 0 0
Mitophagy R-HSA-5205647 5.994392e-02 1.222 0 0
Assembly of the pre-replicative complex R-HSA-68867 5.580752e-02 1.253 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 7.417172e-02 1.130 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 5.285124e-02 1.277 0 0
Vpu mediated degradation of CD4 R-HSA-180534 5.400750e-02 1.268 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 5.994392e-02 1.222 0 0
Regulation of Apoptosis R-HSA-169911 6.626540e-02 1.179 0 0
Signaling by FGFR2 R-HSA-5654738 7.112962e-02 1.148 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 5.387225e-02 1.269 0 0
Kinesins R-HSA-983189 6.396289e-02 1.194 0 0
Organelle biogenesis and maintenance R-HSA-1852241 6.825258e-02 1.166 1 0
ABC-family proteins mediated transport R-HSA-382556 5.108988e-02 1.292 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 6.639329e-02 1.178 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 5.388111e-02 1.269 0 0
FLT3 signaling in disease R-HSA-9682385 7.297349e-02 1.137 0 0
Glucose metabolism R-HSA-70326 5.395142e-02 1.268 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 6.169092e-02 1.210 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 6.169092e-02 1.210 0 0
Signaling by Interleukins R-HSA-449147 5.976076e-02 1.224 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 7.511264e-02 1.124 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.679878e-02 1.115 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 7.679878e-02 1.115 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 7.739733e-02 1.111 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 7.739733e-02 1.111 0 0
DCC mediated attractive signaling R-HSA-418885 7.739733e-02 1.111 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 7.789835e-02 1.108 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 7.900105e-02 1.102 0 0
Assembly Of The HIV Virion R-HSA-175474 7.900105e-02 1.102 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 7.900105e-02 1.102 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 7.900105e-02 1.102 0 0
Ovarian tumor domain proteases R-HSA-5689896 8.006818e-02 1.097 0 0
Degradation of AXIN R-HSA-4641257 8.006818e-02 1.097 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 8.006818e-02 1.097 0 0
Defective Base Excision Repair Associated with NEIL1 R-HSA-9616334 8.030548e-02 1.095 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 8.030548e-02 1.095 0 0
Deletions in the AMER1 gene destabilize the destruction complex R-HSA-5467343 8.030548e-02 1.095 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 8.030548e-02 1.095 0 0
Gene Silencing by RNA R-HSA-211000 8.070758e-02 1.093 0 0
ARMS-mediated activation R-HSA-170984 8.106856e-02 1.091 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 8.106856e-02 1.091 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 8.106856e-02 1.091 0 0
Cellular response to mitochondrial stress R-HSA-9840373 8.106856e-02 1.091 0 0
DAG and IP3 signaling R-HSA-1489509 8.112802e-02 1.091 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 8.112802e-02 1.091 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 8.112802e-02 1.091 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 8.157610e-02 1.088 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 8.268944e-02 1.083 0 0
PIP3 activates AKT signaling R-HSA-1257604 8.427034e-02 1.074 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 8.505678e-02 1.070 0 0
Interleukin-1 family signaling R-HSA-446652 8.520953e-02 1.070 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 8.561237e-02 1.067 0 0
Muscle contraction R-HSA-397014 8.668807e-02 1.062 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.754796e-02 1.058 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 8.792923e-02 1.056 0 0
FGFR2 alternative splicing R-HSA-6803529 8.879302e-02 1.052 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 8.879302e-02 1.052 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 8.925077e-02 1.049 0 0
Regulation of BACH1 activity R-HSA-9708530 8.925077e-02 1.049 0 0
DNA Replication Pre-Initiation R-HSA-69002 8.955309e-02 1.048 0 0
Regulation of gap junction activity R-HSA-191650 9.086399e-02 1.042 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 9.086399e-02 1.042 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 9.086399e-02 1.042 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 9.086399e-02 1.042 0 0
MTF1 activates gene expression R-HSA-5660489 9.086399e-02 1.042 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 9.086399e-02 1.042 0 0
Ub-specific processing proteases R-HSA-5689880 9.106524e-02 1.041 0 0
Cellular response to hypoxia R-HSA-1234174 9.129366e-02 1.040 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 9.352631e-02 1.029 0 0
Trafficking of AMPA receptors R-HSA-399719 9.381018e-02 1.028 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 9.381018e-02 1.028 0 0
MyD88-independent TLR4 cascade R-HSA-166166 9.419697e-02 1.026 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 9.419697e-02 1.026 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.432500e-02 1.025 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.540984e-02 1.020 0 0
Viral Infection Pathways R-HSA-9824446 9.635836e-02 1.016 0 0
Protein-protein interactions at synapses R-HSA-6794362 9.642306e-02 1.016 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 9.715428e-02 1.013 0 0
Regulation of CDH11 function R-HSA-9762292 9.715428e-02 1.013 0 0
Signal attenuation R-HSA-74749 9.715428e-02 1.013 0 0
CASP4 inflammasome assembly R-HSA-9948001 9.715428e-02 1.013 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.019187e-01 0.992 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.019187e-01 0.992 0 0
Intraflagellar transport R-HSA-5620924 1.024926e-01 0.989 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 1.030142e-01 0.987 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.036494e-01 0.984 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.101545e-01 0.958 0 0
Neurodegenerative Diseases R-HSA-8863678 1.101545e-01 0.958 0 0
Signaling by NOTCH R-HSA-157118 1.103708e-01 0.957 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 1.122608e-01 0.950 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 1.126712e-01 0.948 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.126712e-01 0.948 0 0
Bicarbonate transporters R-HSA-425381 1.144122e-01 0.942 0 0
Eukaryotic Translation Termination R-HSA-72764 1.144885e-01 0.941 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 1.153606e-01 0.938 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 1.153606e-01 0.938 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.153606e-01 0.938 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 1.153606e-01 0.938 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.172766e-01 0.931 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 1.172766e-01 0.931 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 1.172766e-01 0.931 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 1.172766e-01 0.931 0 0
Signaling by TGFB family members R-HSA-9006936 1.180754e-01 0.928 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.203985e-01 0.919 0 0
Degradation of CRY and PER proteins R-HSA-9932298 1.212368e-01 0.916 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.212368e-01 0.916 0 0
Translation of Structural Proteins R-HSA-9683701 1.212368e-01 0.916 0 0
TGFBR3 expression R-HSA-9839394 1.216856e-01 0.915 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.541664e-01 0.812 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.541664e-01 0.812 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.541664e-01 0.812 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 1.541664e-01 0.812 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.541664e-01 0.812 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.541664e-01 0.812 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.541664e-01 0.812 0 0
TICAM1 deficiency - HSE R-HSA-5602566 1.541664e-01 0.812 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.541664e-01 0.812 0 0
Defective ACTH causes obesity and POMCD R-HSA-5579031 1.541664e-01 0.812 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.541664e-01 0.812 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.220996e-01 0.653 0 0
TRAF3 deficiency - HSE R-HSA-5602571 2.220996e-01 0.653 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.220996e-01 0.653 0 0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) R-HSA-5619111 2.220996e-01 0.653 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 2.220996e-01 0.653 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.220996e-01 0.653 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.453119e-01 0.838 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 1.453119e-01 0.838 0 0
MECP2 regulates transcription factors R-HSA-9022707 2.045870e-01 0.689 0 0
SOS-mediated signalling R-HSA-112412 2.045870e-01 0.689 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 2.045870e-01 0.689 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.519726e-01 0.818 0 0
Type I hemidesmosome assembly R-HSA-446107 2.351350e-01 0.629 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 2.351350e-01 0.629 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 2.351350e-01 0.629 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.295314e-01 0.888 0 0
GAB1 signalosome R-HSA-180292 1.295314e-01 0.888 0 0
Ephrin signaling R-HSA-3928664 1.295314e-01 0.888 0 0
PKA activation R-HSA-163615 1.295314e-01 0.888 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 2.141299e-01 0.669 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.463314e-01 0.835 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.463314e-01 0.835 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.463314e-01 0.835 0 0
Phosphorylation of the APC/C R-HSA-176412 2.359348e-01 0.627 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 2.359348e-01 0.627 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 1.332949e-01 0.875 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 2.447515e-01 0.611 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 2.044665e-01 0.689 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.932262e-01 0.714 0 0
Viral mRNA Translation R-HSA-192823 1.664810e-01 0.779 0 0
Post-translational protein phosphorylation R-HSA-8957275 2.086003e-01 0.681 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 1.550192e-01 0.810 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.868406e-01 0.729 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 1.868406e-01 0.729 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 1.759145e-01 0.755 0 0
Activation of the pre-replicative complex R-HSA-68962 1.868406e-01 0.729 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.396139e-01 0.855 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 1.759145e-01 0.755 0 0
Nephrin family interactions R-HSA-373753 1.598613e-01 0.796 0 0
COPI-mediated anterograde transport R-HSA-6807878 1.921929e-01 0.716 0 0
PERK regulates gene expression R-HSA-381042 1.442326e-01 0.841 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 2.351350e-01 0.629 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.359348e-01 0.627 0 0
Regulation of mitotic cell cycle R-HSA-453276 1.320120e-01 0.879 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 1.320120e-01 0.879 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 1.720348e-01 0.764 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 2.141299e-01 0.669 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 2.095210e-01 0.679 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 1.266886e-01 0.897 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.869903e-01 0.728 0 0
PLC beta mediated events R-HSA-112043 1.300676e-01 0.886 0 0
Repression of WNT target genes R-HSA-4641265 1.519726e-01 0.818 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.918579e-01 0.717 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 1.442326e-01 0.841 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 1.922312e-01 0.716 0 0
Activation and oligomerization of BAK protein R-HSA-111452 1.541664e-01 0.812 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 2.141299e-01 0.669 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 2.044665e-01 0.689 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 2.044665e-01 0.689 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 2.461336e-01 0.609 0 0
ER-Phagosome pathway R-HSA-1236974 2.042621e-01 0.690 0 0
Prolonged ERK activation events R-HSA-169893 2.359348e-01 0.627 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 2.342200e-01 0.630 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.519726e-01 0.818 0 0
Meiosis R-HSA-1500620 1.627719e-01 0.788 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 2.011646e-01 0.696 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.259753e-01 0.900 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.453119e-01 0.838 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 2.351350e-01 0.629 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 2.351350e-01 0.629 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 1.857150e-01 0.731 0 0
Generic Transcription Pathway R-HSA-212436 2.079107e-01 0.682 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.630973e-01 0.788 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.320120e-01 0.879 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 2.304895e-01 0.637 0 0
G-protein mediated events R-HSA-112040 1.823397e-01 0.739 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 2.304895e-01 0.637 0 0
MAPK family signaling cascades R-HSA-5683057 1.462172e-01 0.835 0 0
Signaling by NOTCH1 R-HSA-1980143 1.722092e-01 0.764 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 2.349008e-01 0.629 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.174797e-01 0.663 0 0
Neurexins and neuroligins R-HSA-6794361 1.353605e-01 0.869 0 0
DNA Replication R-HSA-69306 1.343902e-01 0.872 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 1.707131e-01 0.768 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.541664e-01 0.812 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 1.541664e-01 0.812 0 0
Inhibition of PKR R-HSA-169131 1.541664e-01 0.812 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.220996e-01 0.653 0 0
Transport of connexins along the secretory pathway R-HSA-190827 2.220996e-01 0.653 0 0
Inhibition of Host mRNA Processing and RNA Silencing R-HSA-168315 2.220996e-01 0.653 0 0
CREB phosphorylation R-HSA-199920 1.745393e-01 0.758 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 1.295314e-01 0.888 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 1.332949e-01 0.875 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 1.332949e-01 0.875 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 2.447515e-01 0.611 0 0
Early Phase of HIV Life Cycle R-HSA-162594 1.759145e-01 0.755 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.359348e-01 0.627 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 1.246379e-01 0.904 0 0
G alpha (12/13) signalling events R-HSA-416482 1.897433e-01 0.722 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.380458e-01 0.860 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.598613e-01 0.796 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.453119e-01 0.838 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 1.266886e-01 0.897 0 0
HDACs deacetylate histones R-HSA-3214815 1.630973e-01 0.788 0 0
Regulation of RAS by GAPs R-HSA-5658442 2.166780e-01 0.664 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.431131e-01 0.614 0 0
Glycogen metabolism R-HSA-8982491 2.044665e-01 0.689 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.327333e-01 0.877 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 1.337532e-01 0.874 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.327333e-01 0.877 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.327333e-01 0.877 0 0
Developmental Biology R-HSA-1266738 1.639744e-01 0.785 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.443044e-01 0.841 0 0
Iron uptake and transport R-HSA-917937 1.637424e-01 0.786 0 0
Signaling by FGFR4 R-HSA-5654743 1.402479e-01 0.853 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 1.251605e-01 0.903 0 0
Oligomerization of connexins into connexons R-HSA-190704 2.220996e-01 0.653 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 1.759145e-01 0.755 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.269614e-01 0.644 0 0
RAS processing R-HSA-9648002 1.917467e-01 0.717 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.080338e-01 0.682 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 1.708347e-01 0.767 0 0
Signaling by FGFR3 R-HSA-5654741 1.606012e-01 0.794 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 2.408700e-01 0.618 0 0
Formation of definitive endoderm R-HSA-9823730 1.598613e-01 0.796 0 0
Regulated Necrosis R-HSA-5218859 1.918579e-01 0.717 0 0
Basigin interactions R-HSA-210991 1.759145e-01 0.755 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 2.461336e-01 0.609 0 0
Signaling by FGFR R-HSA-190236 2.086003e-01 0.681 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 1.502626e-01 0.823 0 0
Selenocysteine synthesis R-HSA-2408557 1.524946e-01 0.817 0 0
Cellular response to chemical stress R-HSA-9711123 1.815186e-01 0.741 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 2.254602e-01 0.647 0 0
Syndecan interactions R-HSA-3000170 2.269614e-01 0.644 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 2.045870e-01 0.689 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.442948e-01 0.612 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 1.606012e-01 0.794 0 0
Plasma lipoprotein clearance R-HSA-8964043 1.917467e-01 0.717 0 0
ABC transporter disorders R-HSA-5619084 1.897433e-01 0.722 0 0
Hedgehog 'on' state R-HSA-5632684 2.216298e-01 0.654 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 2.045870e-01 0.689 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.141299e-01 0.669 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 1.353605e-01 0.869 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.295314e-01 0.888 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 1.759145e-01 0.755 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 2.216298e-01 0.654 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 2.359348e-01 0.627 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.924866e-01 0.716 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.402479e-01 0.853 0 0
Inositol phosphate metabolism R-HSA-1483249 1.639824e-01 0.785 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.678444e-01 0.775 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 1.759145e-01 0.755 0 0
Non-canonical inflammasome activation R-HSA-9686114 1.927926e-01 0.715 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 1.729057e-01 0.762 0 0
FLT3 Signaling R-HSA-9607240 2.174797e-01 0.663 0 0
Semaphorin interactions R-HSA-373755 2.479584e-01 0.606 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 2.548320e-01 0.594 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 2.548320e-01 0.594 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 2.581003e-01 0.588 0 0
Synthesis of PG R-HSA-1483148 2.581003e-01 0.588 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 2.581003e-01 0.588 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 2.581003e-01 0.588 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 2.616748e-01 0.582 0 0
HDMs demethylate histones R-HSA-3214842 2.628356e-01 0.580 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.628356e-01 0.580 0 0
Interleukin-7 signaling R-HSA-1266695 2.628356e-01 0.580 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.635612e-01 0.579 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 2.658698e-01 0.575 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 2.659094e-01 0.575 0 0
Lipophagy R-HSA-9613354 2.659094e-01 0.575 0 0
WNT mediated activation of DVL R-HSA-201688 2.659094e-01 0.575 0 0
Calcineurin activates NFAT R-HSA-2025928 2.659094e-01 0.575 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 2.659094e-01 0.575 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 2.659094e-01 0.575 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 2.659094e-01 0.575 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 2.659094e-01 0.575 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 2.659094e-01 0.575 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 2.659094e-01 0.575 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 2.659094e-01 0.575 0 0
Protein localization R-HSA-9609507 2.710830e-01 0.567 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 2.711450e-01 0.567 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.720050e-01 0.565 0 0
RMTs methylate histone arginines R-HSA-3214858 2.720050e-01 0.565 0 0
Signaling by WNT R-HSA-195721 2.792300e-01 0.554 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 2.805253e-01 0.552 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 2.805253e-01 0.552 0 0
Suppression of phagosomal maturation R-HSA-9637687 2.811594e-01 0.551 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 2.829580e-01 0.548 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 2.845804e-01 0.546 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 2.845804e-01 0.546 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 2.845804e-01 0.546 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 2.845804e-01 0.546 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 2.845804e-01 0.546 0 0
mRNA Editing: A to I Conversion R-HSA-75064 2.845804e-01 0.546 0 0
C6 deamination of adenosine R-HSA-75102 2.845804e-01 0.546 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 2.845804e-01 0.546 0 0
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis R-HSA-9708296 2.845804e-01 0.546 0 0
Translation of Structural Proteins R-HSA-9694635 2.857687e-01 0.544 0 0
G1/S Transition R-HSA-69206 2.886595e-01 0.540 0 0
Ion homeostasis R-HSA-5578775 2.915376e-01 0.535 0 0
Signaling by FGFR1 R-HSA-5654736 2.915376e-01 0.535 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.915376e-01 0.535 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.925809e-01 0.534 0 0
RET signaling R-HSA-8853659 2.933782e-01 0.533 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 2.933782e-01 0.533 0 0
Co-inhibition by PD-1 R-HSA-389948 2.953531e-01 0.530 0 0
2-LTR circle formation R-HSA-164843 2.966772e-01 0.528 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 2.966772e-01 0.528 0 0
PI3K/AKT activation R-HSA-198203 2.966772e-01 0.528 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 2.966772e-01 0.528 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 2.966772e-01 0.528 0 0
Signaling by Leptin R-HSA-2586552 2.966772e-01 0.528 0 0
RNA Polymerase I Transcription R-HSA-73864 2.969314e-01 0.527 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 2.996698e-01 0.523 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 2.996698e-01 0.523 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 2.996698e-01 0.523 0 0
Signaling by TGFBR3 R-HSA-9839373 3.004201e-01 0.522 0 0
Regulation of pyruvate metabolism R-HSA-9861718 3.004201e-01 0.522 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 3.031146e-01 0.518 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 3.031146e-01 0.518 0 0
Mismatch Repair R-HSA-5358508 3.031146e-01 0.518 0 0
PKA activation in glucagon signalling R-HSA-164378 3.031146e-01 0.518 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 3.031146e-01 0.518 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 3.034461e-01 0.518 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 3.045777e-01 0.516 0 0
Transcription of the HIV genome R-HSA-167172 3.069671e-01 0.513 0 0
Antigen processing-Cross presentation R-HSA-1236975 3.079822e-01 0.511 0 0
Disorders of transmembrane transporters R-HSA-5619115 3.136813e-01 0.504 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 3.148327e-01 0.502 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 3.148886e-01 0.502 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 3.183156e-01 0.497 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 3.191331e-01 0.496 0 0
Downstream TCR signaling R-HSA-202424 3.193323e-01 0.496 0 0
Signaling by MET R-HSA-6806834 3.195626e-01 0.495 0 0
Signaling by NTRKs R-HSA-166520 3.198322e-01 0.495 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 3.256850e-01 0.487 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 3.257794e-01 0.487 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 3.257794e-01 0.487 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 3.257794e-01 0.487 0 0
Rap1 signalling R-HSA-392517 3.257794e-01 0.487 0 0
Maturation of nucleoprotein R-HSA-9694631 3.257794e-01 0.487 0 0
STING mediated induction of host immune responses R-HSA-1834941 3.257794e-01 0.487 0 0
PECAM1 interactions R-HSA-210990 3.272409e-01 0.485 0 0
Formation of the posterior neural plate R-HSA-9832991 3.272409e-01 0.485 0 0
vRNP Assembly R-HSA-192905 3.272409e-01 0.485 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 3.272409e-01 0.485 0 0
TCR signaling R-HSA-202403 3.273128e-01 0.485 0 0
Gluconeogenesis R-HSA-70263 3.293508e-01 0.482 0 0
Peroxisomal protein import R-HSA-9033241 3.309822e-01 0.480 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 3.313881e-01 0.480 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 3.313881e-01 0.480 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 3.342309e-01 0.476 0 0
Potential therapeutics for SARS R-HSA-9679191 3.364422e-01 0.473 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.370474e-01 0.472 0 0
DARPP-32 events R-HSA-180024 3.370474e-01 0.472 0 0
Neutrophil degranulation R-HSA-6798695 3.372284e-01 0.472 0 0
Reproduction R-HSA-1474165 3.417007e-01 0.466 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.419828e-01 0.466 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.419828e-01 0.466 0 0
Axonal growth stimulation R-HSA-209563 3.420462e-01 0.466 0 0
MET activates PTPN11 R-HSA-8865999 3.420462e-01 0.466 0 0
Defective ABCC2 causes DJS R-HSA-5679001 3.420462e-01 0.466 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 3.420462e-01 0.466 0 0
HCMV Early Events R-HSA-9609690 3.482962e-01 0.458 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 3.484376e-01 0.458 0 0
Signal transduction by L1 R-HSA-445144 3.484376e-01 0.458 0 0
Protein hydroxylation R-HSA-9629569 3.484376e-01 0.458 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 3.484376e-01 0.458 0 0
Interleukin-37 signaling R-HSA-9008059 3.558184e-01 0.449 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 3.561104e-01 0.448 0 0
Signaling by AMER1 mutants R-HSA-4839748 3.574351e-01 0.447 0 0
Signaling by GSK3beta mutants R-HSA-5339716 3.574351e-01 0.447 0 0
Integration of provirus R-HSA-162592 3.574351e-01 0.447 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 3.574351e-01 0.447 0 0
HIV Transcription Elongation R-HSA-167169 3.583348e-01 0.446 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.583348e-01 0.446 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 3.583348e-01 0.446 0 0
MHC class II antigen presentation R-HSA-2132295 3.632246e-01 0.440 0 0
Ca2+ pathway R-HSA-4086398 3.685504e-01 0.434 0 0
Opioid Signalling R-HSA-111885 3.702096e-01 0.432 0 0
Lagging Strand Synthesis R-HSA-69186 3.710137e-01 0.431 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 3.710137e-01 0.431 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 3.711374e-01 0.430 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 3.784158e-01 0.422 0 0
Signaling by ERBB4 R-HSA-1236394 3.810251e-01 0.419 0 0
Signaling by PTK6 R-HSA-8848021 3.846007e-01 0.415 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 3.846007e-01 0.415 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 3.848110e-01 0.415 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 3.871220e-01 0.412 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 3.871220e-01 0.412 0 0
Polymerase switching R-HSA-69091 3.871220e-01 0.412 0 0
Leading Strand Synthesis R-HSA-69109 3.871220e-01 0.412 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 3.871220e-01 0.412 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 3.871220e-01 0.412 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 3.871220e-01 0.412 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 3.871220e-01 0.412 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 3.871220e-01 0.412 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 3.871220e-01 0.412 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 3.880238e-01 0.411 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 3.910817e-01 0.408 0 0
Signaling by FGFR1 in disease R-HSA-5655302 3.910817e-01 0.408 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 3.916607e-01 0.407 0 0
Signaling by WNT in cancer R-HSA-4791275 3.933007e-01 0.405 0 0
Diseases of mitotic cell cycle R-HSA-9675126 3.933007e-01 0.405 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 3.948992e-01 0.404 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 3.948992e-01 0.404 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 3.948992e-01 0.404 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 3.948992e-01 0.404 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 3.948992e-01 0.404 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 3.948992e-01 0.404 0 0
GABA synthesis R-HSA-888568 3.948992e-01 0.404 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 3.948992e-01 0.404 0 0
NADE modulates death signalling R-HSA-205025 3.948992e-01 0.404 0 0
Toll-like Receptor Cascades R-HSA-168898 3.981875e-01 0.400 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 4.008103e-01 0.397 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 4.060264e-01 0.391 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 4.060409e-01 0.391 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 4.069188e-01 0.390 0 0
Integrin signaling R-HSA-354192 4.119300e-01 0.385 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 4.119300e-01 0.385 0 0
FGFR1 mutant receptor activation R-HSA-1839124 4.119300e-01 0.385 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 4.119300e-01 0.385 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 4.149717e-01 0.382 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 4.156499e-01 0.381 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 4.156499e-01 0.381 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 4.156499e-01 0.381 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 4.161884e-01 0.381 0 0
Formation of axial mesoderm R-HSA-9796292 4.161884e-01 0.381 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 4.161884e-01 0.381 0 0
Frs2-mediated activation R-HSA-170968 4.161884e-01 0.381 0 0
Maturation of nucleoprotein R-HSA-9683610 4.161884e-01 0.381 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 4.267099e-01 0.370 0 0
Transmission across Chemical Synapses R-HSA-112315 4.294001e-01 0.367 0 0
Resolution of D-Loop Structures R-HSA-5693537 4.304343e-01 0.366 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 4.304343e-01 0.366 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 4.375913e-01 0.359 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 4.375913e-01 0.359 0 0
FOXO-mediated transcription R-HSA-9614085 4.400979e-01 0.356 0 0
HATs acetylate histones R-HSA-3214847 4.400979e-01 0.356 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 4.435095e-01 0.353 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.435095e-01 0.353 0 0
Activation of AKT2 R-HSA-165158 4.435095e-01 0.353 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 4.435095e-01 0.353 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 4.435095e-01 0.353 0 0
Reelin signalling pathway R-HSA-8866376 4.435095e-01 0.353 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 4.435095e-01 0.353 0 0
Muscarinic acetylcholine receptors R-HSA-390648 4.435095e-01 0.353 0 0
Retrograde neurotrophin signalling R-HSA-177504 4.445426e-01 0.352 0 0
Regulation of KIT signaling R-HSA-1433559 4.445426e-01 0.352 0 0
Signal regulatory protein family interactions R-HSA-391160 4.445426e-01 0.352 0 0
Zinc transporters R-HSA-435354 4.445426e-01 0.352 0 0
NOD1/2 Signaling Pathway R-HSA-168638 4.487790e-01 0.348 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 4.487790e-01 0.348 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 4.517810e-01 0.345 0 0
Nucleosome assembly R-HSA-774815 4.559762e-01 0.341 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 4.559762e-01 0.341 0 0
Somitogenesis R-HSA-9824272 4.559762e-01 0.341 0 0
Chromosome Maintenance R-HSA-73886 4.567677e-01 0.340 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 4.592127e-01 0.338 0 0
Deadenylation of mRNA R-HSA-429947 4.592127e-01 0.338 0 0
Complex III assembly R-HSA-9865881 4.592127e-01 0.338 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 4.621298e-01 0.335 0 0
Signalling to ERKs R-HSA-187687 4.669322e-01 0.331 0 0
Diseases of DNA repair R-HSA-9675135 4.719295e-01 0.326 0 0
Processive synthesis on the lagging strand R-HSA-69183 4.721114e-01 0.326 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 4.721114e-01 0.326 0 0
Formation of the anterior neural plate R-HSA-9823739 4.721114e-01 0.326 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 4.721114e-01 0.326 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 4.804697e-01 0.318 0 0
Acyl chain remodelling of PS R-HSA-1482801 4.804697e-01 0.318 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 4.804697e-01 0.318 0 0
Formation of the nephric duct R-HSA-9830364 4.804697e-01 0.318 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 4.805548e-01 0.318 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 4.824221e-01 0.317 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 4.882174e-01 0.311 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 4.882174e-01 0.311 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 4.882174e-01 0.311 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 4.882174e-01 0.311 0 0
Toxicity of botulinum toxin type E (botE) R-HSA-5250992 4.882174e-01 0.311 0 0
Cam-PDE 1 activation R-HSA-111957 4.882174e-01 0.311 0 0
PKB-mediated events R-HSA-109703 4.882174e-01 0.311 0 0
PDE3B signalling R-HSA-165160 4.882174e-01 0.311 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.882174e-01 0.311 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 4.882174e-01 0.311 0 0
Diseases of Base Excision Repair R-HSA-9605308 4.882174e-01 0.311 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 4.882174e-01 0.311 0 0
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397 4.882174e-01 0.311 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 4.882174e-01 0.311 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 4.882174e-01 0.311 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 4.882174e-01 0.311 0 0
Amino acid transport across the plasma membrane R-HSA-352230 4.898205e-01 0.310 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 4.988380e-01 0.302 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 4.988380e-01 0.302 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 4.988380e-01 0.302 0 0
Killing mechanisms R-HSA-9664420 4.988380e-01 0.302 0 0
Virus Assembly and Release R-HSA-168268 4.988380e-01 0.302 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 5.013234e-01 0.300 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 5.013234e-01 0.300 0 0
Developmental Cell Lineages R-HSA-9734767 5.023686e-01 0.299 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 5.033591e-01 0.298 0 0
NGF-stimulated transcription R-HSA-9031628 5.033591e-01 0.298 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 5.044902e-01 0.297 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.159848e-01 0.287 1 0
MAP kinase activation R-HSA-450294 5.179924e-01 0.286 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 5.217401e-01 0.283 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 5.246800e-01 0.280 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.246800e-01 0.280 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.246800e-01 0.280 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 5.246800e-01 0.280 0 0
Response to metal ions R-HSA-5660526 5.246800e-01 0.280 0 0
Signaling by Nuclear Receptors R-HSA-9006931 5.287219e-01 0.277 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 5.293359e-01 0.276 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 5.293359e-01 0.276 0 0
Signaling by LTK in cancer R-HSA-9842640 5.293359e-01 0.276 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 5.293359e-01 0.276 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.293359e-01 0.276 0 0
Autointegration results in viral DNA circles R-HSA-177539 5.293359e-01 0.276 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 5.293359e-01 0.276 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 5.293359e-01 0.276 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 5.293359e-01 0.276 0 0
VLDL assembly R-HSA-8866423 5.293359e-01 0.276 0 0
Nef and signal transduction R-HSA-164944 5.293359e-01 0.276 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 5.293359e-01 0.276 0 0
Signaling by FGFR in disease R-HSA-1226099 5.302163e-01 0.276 0 0
Gastrulation R-HSA-9758941 5.339476e-01 0.273 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 5.370802e-01 0.270 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 5.371449e-01 0.270 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 5.416910e-01 0.266 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 5.416910e-01 0.266 0 0
Formation of the Early Elongation Complex R-HSA-113418 5.416910e-01 0.266 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 5.496069e-01 0.260 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 5.496069e-01 0.260 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 5.496069e-01 0.260 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 5.496069e-01 0.260 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 5.496069e-01 0.260 0 0
Specification of primordial germ cells R-HSA-9827857 5.496069e-01 0.260 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 5.538854e-01 0.257 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 5.538854e-01 0.257 0 0
Diseases of Immune System R-HSA-5260271 5.538854e-01 0.257 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.590474e-01 0.253 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 5.611519e-01 0.251 0 0
mRNA Capping R-HSA-72086 5.611519e-01 0.251 0 0
Regulation of gene expression in beta cells R-HSA-210745 5.611519e-01 0.251 0 0
Platelet calcium homeostasis R-HSA-418360 5.611519e-01 0.251 0 0
Diseases of programmed cell death R-HSA-9645723 5.641223e-01 0.249 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 5.671531e-01 0.246 0 0
TRIF-mediated programmed cell death R-HSA-2562578 5.671531e-01 0.246 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 5.671531e-01 0.246 0 0
Disinhibition of SNARE formation R-HSA-114516 5.671531e-01 0.246 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 5.671531e-01 0.246 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 5.671531e-01 0.246 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 5.671531e-01 0.246 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 5.671531e-01 0.246 0 0
LDL remodeling R-HSA-8964041 5.671531e-01 0.246 0 0
VLDL clearance R-HSA-8964046 5.671531e-01 0.246 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 5.671531e-01 0.246 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 5.671531e-01 0.246 0 0
CHL1 interactions R-HSA-447041 5.671531e-01 0.246 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 5.671531e-01 0.246 0 0
Platelet sensitization by LDL R-HSA-432142 5.735989e-01 0.241 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 5.735989e-01 0.241 0 0
HCMV Infection R-HSA-9609646 5.796572e-01 0.237 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 5.801029e-01 0.236 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 5.801029e-01 0.236 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 5.801029e-01 0.236 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 5.801029e-01 0.236 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 5.805791e-01 0.236 0 0
SLC transporter disorders R-HSA-5619102 5.841167e-01 0.234 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 5.864890e-01 0.232 0 0
HIV Transcription Initiation R-HSA-167161 5.864890e-01 0.232 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 5.864890e-01 0.232 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 5.864890e-01 0.232 0 0
Sensory processing of sound R-HSA-9659379 5.920263e-01 0.228 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 5.966454e-01 0.224 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 5.966454e-01 0.224 0 0
Germ layer formation at gastrulation R-HSA-9754189 5.966454e-01 0.224 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 5.966454e-01 0.224 0 0
The NLRP3 inflammasome R-HSA-844456 5.966454e-01 0.224 0 0
Specification of the neural plate border R-HSA-9834899 5.966454e-01 0.224 0 0
SLC-mediated transport of amino acids R-HSA-9958863 5.983858e-01 0.223 0 0
RSK activation R-HSA-444257 6.019338e-01 0.220 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 6.019338e-01 0.220 0 0
phospho-PLA2 pathway R-HSA-111995 6.019338e-01 0.220 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 6.019338e-01 0.220 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 6.019338e-01 0.220 0 0
MET receptor recycling R-HSA-8875656 6.019338e-01 0.220 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 6.019338e-01 0.220 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 6.019338e-01 0.220 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 6.019338e-01 0.220 0 0
TGFBR3 PTM regulation R-HSA-9839383 6.019338e-01 0.220 0 0
Alpha-defensins R-HSA-1462054 6.019338e-01 0.220 0 0
Sodium/Proton exchangers R-HSA-425986 6.019338e-01 0.220 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 6.019338e-01 0.220 0 0
Interleukin-23 signaling R-HSA-9020933 6.019338e-01 0.220 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 6.022593e-01 0.220 0 0
Amyloid fiber formation R-HSA-977225 6.155704e-01 0.211 0 0
G0 and Early G1 R-HSA-1538133 6.164147e-01 0.210 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 6.164147e-01 0.210 0 0
tRNA processing R-HSA-72306 6.167011e-01 0.210 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 6.176600e-01 0.209 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 6.187434e-01 0.208 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 6.187434e-01 0.208 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 6.187434e-01 0.208 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 6.187434e-01 0.208 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 6.187434e-01 0.208 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 6.200014e-01 0.208 0 0
Proteasome assembly R-HSA-9907900 6.326820e-01 0.199 0 0
Netrin-1 signaling R-HSA-373752 6.326820e-01 0.199 0 0
Cyclin D associated events in G1 R-HSA-69231 6.326820e-01 0.199 0 0
G1 Phase R-HSA-69236 6.326820e-01 0.199 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 6.337540e-01 0.198 0 0
Nuclear RNA decay R-HSA-9930044 6.337540e-01 0.198 0 0
Cardiogenesis R-HSA-9733709 6.337540e-01 0.198 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 6.339216e-01 0.198 0 0
Toxicity of botulinum toxin type A (botA) R-HSA-5250968 6.339216e-01 0.198 0 0
p75NTR regulates axonogenesis R-HSA-193697 6.339216e-01 0.198 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 6.339216e-01 0.198 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 6.339216e-01 0.198 0 0
GP1b-IX-V activation signalling R-HSA-430116 6.339216e-01 0.198 0 0
mRNA Editing R-HSA-75072 6.339216e-01 0.198 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.339216e-01 0.198 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 6.339216e-01 0.198 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 6.339216e-01 0.198 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 6.339216e-01 0.198 0 0
Regulated proteolysis of p75NTR R-HSA-193692 6.339216e-01 0.198 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 6.339216e-01 0.198 0 0
Interleukin-17 signaling R-HSA-448424 6.357645e-01 0.197 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 6.383586e-01 0.195 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 6.398965e-01 0.194 0 0
G-protein activation R-HSA-202040 6.398965e-01 0.194 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.398965e-01 0.194 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 6.398965e-01 0.194 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 6.398965e-01 0.194 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 6.473179e-01 0.189 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 6.473179e-01 0.189 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 6.473179e-01 0.189 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 6.473179e-01 0.189 0 0
Platelet activation, signaling and aggregation R-HSA-76002 6.562969e-01 0.183 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 6.596652e-01 0.181 0 0
Extension of Telomeres R-HSA-180786 6.596652e-01 0.181 0 0
Selenoamino acid metabolism R-HSA-2408522 6.601053e-01 0.180 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 6.601139e-01 0.180 0 0
Serine metabolism R-HSA-977347 6.601139e-01 0.180 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 6.633407e-01 0.178 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 6.633407e-01 0.178 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 6.633407e-01 0.178 0 0
Binding and entry of HIV virion R-HSA-173107 6.633407e-01 0.178 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 6.633407e-01 0.178 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 6.633407e-01 0.178 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 6.633407e-01 0.178 0 0
Sperm Motility And Taxes R-HSA-1300642 6.633407e-01 0.178 0 0
Peptide hormone biosynthesis R-HSA-209952 6.633407e-01 0.178 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 6.633407e-01 0.178 0 0
Interleukin-27 signaling R-HSA-9020956 6.633407e-01 0.178 0 0
Maturation of spike protein R-HSA-9683686 6.633407e-01 0.178 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 6.667692e-01 0.176 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 6.667692e-01 0.176 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 6.747452e-01 0.171 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 6.754105e-01 0.170 0 0
LDL clearance R-HSA-8964038 6.794093e-01 0.168 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 6.824411e-01 0.166 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 6.844008e-01 0.165 0 0
Formation of paraxial mesoderm R-HSA-9793380 6.844008e-01 0.165 0 0
Collagen degradation R-HSA-1442490 6.844008e-01 0.165 0 0
GPER1 signaling R-HSA-9634597 6.888604e-01 0.162 0 0
Metal ion SLC transporters R-HSA-425410 6.888604e-01 0.162 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 6.903973e-01 0.161 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 6.903973e-01 0.161 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 6.903973e-01 0.161 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 6.903973e-01 0.161 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 6.903973e-01 0.161 0 0
Ionotropic activity of kainate receptors R-HSA-451306 6.903973e-01 0.161 0 0
Signaling by APC mutants R-HSA-4839744 6.903973e-01 0.161 0 0
Chylomicron assembly R-HSA-8963888 6.903973e-01 0.161 0 0
Synthesis of PI R-HSA-1483226 6.903973e-01 0.161 0 0
Propionyl-CoA catabolism R-HSA-71032 6.903973e-01 0.161 0 0
Suppression of apoptosis R-HSA-9635465 6.903973e-01 0.161 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 6.903973e-01 0.161 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 6.903973e-01 0.161 0 0
Dissolution of Fibrin Clot R-HSA-75205 6.903973e-01 0.161 0 0
Pyruvate metabolism R-HSA-70268 6.917721e-01 0.160 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 6.932565e-01 0.159 0 0
NCAM signaling for neurite out-growth R-HSA-375165 6.963036e-01 0.157 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.978002e-01 0.156 0 0
Growth hormone receptor signaling R-HSA-982772 6.978002e-01 0.156 0 0
Neuronal System R-HSA-112316 7.010866e-01 0.154 0 0
HCMV Late Events R-HSA-9610379 7.036167e-01 0.153 0 0
NCAM1 interactions R-HSA-419037 7.121206e-01 0.147 0 0
PI3K Cascade R-HSA-109704 7.145606e-01 0.146 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 7.152808e-01 0.146 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 7.152808e-01 0.146 0 0
Plasmalogen biosynthesis R-HSA-75896 7.152808e-01 0.146 0 0
Signaling by AXIN mutants R-HSA-4839735 7.152808e-01 0.146 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 7.152808e-01 0.146 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 7.152808e-01 0.146 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 7.152808e-01 0.146 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 7.152808e-01 0.146 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 7.152808e-01 0.146 0 0
Sodium/Calcium exchangers R-HSA-425561 7.152808e-01 0.146 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.153075e-01 0.146 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.153075e-01 0.146 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.153075e-01 0.146 0 0
Insulin receptor signalling cascade R-HSA-74751 7.191702e-01 0.143 0 0
IGF1R signaling cascade R-HSA-2428924 7.191702e-01 0.143 0 0
Ion transport by P-type ATPases R-HSA-936837 7.191702e-01 0.143 0 0
Integrin cell surface interactions R-HSA-216083 7.247099e-01 0.140 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 7.261371e-01 0.139 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 7.261371e-01 0.139 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 7.301330e-01 0.137 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 7.319543e-01 0.136 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 7.319543e-01 0.136 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 7.381657e-01 0.132 0 0
GRB2 events in EGFR signaling R-HSA-179812 7.381657e-01 0.132 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 7.381657e-01 0.132 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 7.381657e-01 0.132 0 0
Signaling by LTK R-HSA-9842663 7.381657e-01 0.132 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 7.381657e-01 0.132 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 7.381657e-01 0.132 0 0
Interleukin-35 Signalling R-HSA-8984722 7.381657e-01 0.132 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 7.381657e-01 0.132 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 7.396132e-01 0.131 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 7.396132e-01 0.131 0 0
Signaling by ALK R-HSA-201556 7.396132e-01 0.131 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 7.477658e-01 0.126 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 7.525574e-01 0.123 0 0
Infectious disease R-HSA-5663205 7.531148e-01 0.123 0 0
RSV-host interactions R-HSA-9833110 7.535217e-01 0.123 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 7.592125e-01 0.120 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 7.592125e-01 0.120 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 7.592125e-01 0.120 0 0
Interleukin-6 signaling R-HSA-1059683 7.592125e-01 0.120 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 7.592125e-01 0.120 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 7.627687e-01 0.118 0 0
Cristae formation R-HSA-8949613 7.627687e-01 0.118 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 7.627687e-01 0.118 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.627687e-01 0.118 0 0
Insulin processing R-HSA-264876 7.627687e-01 0.118 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 7.627687e-01 0.118 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 7.649789e-01 0.116 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 7.685412e-01 0.114 0 0
Cytoprotection by HMOX1 R-HSA-9707564 7.719657e-01 0.112 0 0
Scavenging by Class A Receptors R-HSA-3000480 7.768884e-01 0.110 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 7.768884e-01 0.110 0 0
Insulin receptor recycling R-HSA-77387 7.769908e-01 0.110 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 7.769908e-01 0.110 0 0
Inflammasomes R-HSA-622312 7.769908e-01 0.110 0 0
Pyroptosis R-HSA-5620971 7.769908e-01 0.110 0 0
Removal of the Flap Intermediate R-HSA-69166 7.785687e-01 0.109 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 7.785687e-01 0.109 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 7.785687e-01 0.109 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 7.785687e-01 0.109 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 7.785687e-01 0.109 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 7.785687e-01 0.109 0 0
Hydrolysis of LPC R-HSA-1483115 7.785687e-01 0.109 0 0
Signaling by FGFR4 in disease R-HSA-5655291 7.785687e-01 0.109 0 0
Physiological factors R-HSA-5578768 7.785687e-01 0.109 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 7.785687e-01 0.109 0 0
HDL assembly R-HSA-8963896 7.785687e-01 0.109 0 0
Acyl chain remodeling of CL R-HSA-1482798 7.785687e-01 0.109 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 7.785687e-01 0.109 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 7.821917e-01 0.107 0 0
Adipogenesis R-HSA-9843745 7.845053e-01 0.105 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 7.882970e-01 0.103 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 7.882970e-01 0.103 0 0
Signaling by Erythropoietin R-HSA-9006335 7.904607e-01 0.102 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 7.904607e-01 0.102 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 7.904607e-01 0.102 0 0
Circadian clock R-HSA-9909396 7.911967e-01 0.102 1 0
Neddylation R-HSA-8951664 7.919482e-01 0.101 0 0
IRS-mediated signalling R-HSA-112399 7.921248e-01 0.101 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 7.963699e-01 0.099 0 0
Erythropoietin activates RAS R-HSA-9027284 7.963699e-01 0.099 0 0
SHC1 events in EGFR signaling R-HSA-180336 7.963699e-01 0.099 0 0
G beta:gamma signalling through BTK R-HSA-8964315 7.963699e-01 0.099 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 7.963699e-01 0.099 0 0
Biotin transport and metabolism R-HSA-196780 7.963699e-01 0.099 0 0
p38MAPK events R-HSA-171007 7.963699e-01 0.099 0 0
DNA Damage Reversal R-HSA-73942 7.963699e-01 0.099 0 0
Telomere Maintenance R-HSA-157579 7.978293e-01 0.098 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 7.983830e-01 0.098 0 0
TBC/RABGAPs R-HSA-8854214 7.992170e-01 0.097 0 0
Signaling by SCF-KIT R-HSA-1433557 7.992170e-01 0.097 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.032072e-01 0.095 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 8.032072e-01 0.095 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 8.067373e-01 0.093 0 0
Regulation of beta-cell development R-HSA-186712 8.108973e-01 0.091 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 8.108973e-01 0.091 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 8.127410e-01 0.090 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 8.127410e-01 0.090 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 8.127410e-01 0.090 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 8.127410e-01 0.090 0 0
Activation of SMO R-HSA-5635838 8.127410e-01 0.090 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 8.127410e-01 0.090 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 8.127410e-01 0.090 0 0
Attachment and Entry R-HSA-9678110 8.127410e-01 0.090 0 0
Atorvastatin ADME R-HSA-9754706 8.127410e-01 0.090 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 8.152598e-01 0.089 0 0
Molecules associated with elastic fibres R-HSA-2129379 8.152598e-01 0.089 0 0
Extracellular matrix organization R-HSA-1474244 8.176572e-01 0.087 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 8.186009e-01 0.087 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 8.197511e-01 0.086 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 8.266474e-01 0.083 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 8.277969e-01 0.082 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 8.277969e-01 0.082 1 1
TRAF3-dependent IRF activation pathway R-HSA-918233 8.277969e-01 0.082 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 8.277969e-01 0.082 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 8.277969e-01 0.082 0 0
Coenzyme A biosynthesis R-HSA-196783 8.277969e-01 0.082 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 8.277969e-01 0.082 0 0
Aquaporin-mediated transport R-HSA-445717 8.282604e-01 0.082 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 8.291740e-01 0.081 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 8.291740e-01 0.081 0 0
Neurotransmitter release cycle R-HSA-112310 8.345264e-01 0.079 0 0
Base Excision Repair R-HSA-73884 8.345264e-01 0.079 0 0
Mitochondrial protein import R-HSA-1268020 8.364332e-01 0.078 0 0
Signaling by PDGF R-HSA-186797 8.364332e-01 0.078 0 0
G-protein beta:gamma signalling R-HSA-397795 8.373991e-01 0.077 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 8.412777e-01 0.075 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 8.416430e-01 0.075 0 0
Choline catabolism R-HSA-6798163 8.416430e-01 0.075 0 0
Uptake and function of anthrax toxins R-HSA-5210891 8.416430e-01 0.075 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.416430e-01 0.075 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.475435e-01 0.072 0 0
Miscellaneous transport and binding events R-HSA-5223345 8.475435e-01 0.072 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 8.475435e-01 0.072 0 0
Heme degradation R-HSA-189483 8.475435e-01 0.072 0 0
Signaling by Insulin receptor R-HSA-74752 8.541103e-01 0.068 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 8.543767e-01 0.068 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 8.543767e-01 0.068 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 8.543767e-01 0.068 0 0
Presynaptic function of Kainate receptors R-HSA-500657 8.543767e-01 0.068 0 0
Synaptic adhesion-like molecules R-HSA-8849932 8.543767e-01 0.068 0 0
Apoptotic factor-mediated response R-HSA-111471 8.543767e-01 0.068 0 0
Rab regulation of trafficking R-HSA-9007101 8.556669e-01 0.068 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 8.571088e-01 0.067 0 0
Signal amplification R-HSA-392518 8.571088e-01 0.067 0 0
eNOS activation R-HSA-203615 8.571088e-01 0.067 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 8.571088e-01 0.067 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 8.571088e-01 0.067 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 8.571088e-01 0.067 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.571088e-01 0.067 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.630870e-01 0.064 0 0
Collagen formation R-HSA-1474290 8.660791e-01 0.062 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 8.660870e-01 0.062 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 8.660870e-01 0.062 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 8.660870e-01 0.062 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 8.660870e-01 0.062 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 8.660870e-01 0.062 0 0
Transferrin endocytosis and recycling R-HSA-917977 8.661223e-01 0.062 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.661223e-01 0.062 0 0
The phototransduction cascade R-HSA-2514856 8.705822e-01 0.060 0 0
Triglyceride catabolism R-HSA-163560 8.746110e-01 0.058 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.746110e-01 0.058 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.746110e-01 0.058 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 8.768564e-01 0.057 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 8.768564e-01 0.057 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 8.768564e-01 0.057 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 8.768564e-01 0.057 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 8.768564e-01 0.057 0 0
Co-inhibition by CTLA4 R-HSA-389513 8.768564e-01 0.057 0 0
Signaling by NODAL R-HSA-1181150 8.768564e-01 0.057 0 0
Creatine metabolism R-HSA-71288 8.768564e-01 0.057 0 0
Acyl chain remodelling of PI R-HSA-1482922 8.768564e-01 0.057 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 8.768564e-01 0.057 0 0
Pregnenolone biosynthesis R-HSA-196108 8.768564e-01 0.057 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.777124e-01 0.057 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 8.788863e-01 0.056 0 0
Collagen chain trimerization R-HSA-8948216 8.826010e-01 0.054 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 8.828177e-01 0.054 1 0
Amino acids regulate mTORC1 R-HSA-9639288 8.844914e-01 0.053 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 8.867602e-01 0.052 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 8.867602e-01 0.052 0 0
ERK/MAPK targets R-HSA-198753 8.867602e-01 0.052 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 8.867602e-01 0.052 0 0
Signalling to RAS R-HSA-167044 8.867602e-01 0.052 0 0
Acyl chain remodelling of PG R-HSA-1482925 8.867602e-01 0.052 0 0
MET promotes cell motility R-HSA-8875878 8.901175e-01 0.051 0 0
Elastic fibre formation R-HSA-1566948 8.901175e-01 0.051 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 8.901175e-01 0.051 0 0
Regulation of insulin secretion R-HSA-422356 8.924670e-01 0.049 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 8.932992e-01 0.049 0 0
Immune System R-HSA-168256 8.942423e-01 0.049 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 8.958681e-01 0.048 0 0
Androgen biosynthesis R-HSA-193048 8.958681e-01 0.048 0 0
Glucocorticoid biosynthesis R-HSA-194002 8.958681e-01 0.048 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 8.958681e-01 0.048 0 0
Mitochondrial calcium ion transport R-HSA-8949215 8.958681e-01 0.048 0 0
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377 8.958681e-01 0.048 0 0
Attachment and Entry R-HSA-9694614 8.958681e-01 0.048 0 0
Ribavirin ADME R-HSA-9755088 8.958681e-01 0.048 0 0
ECM proteoglycans R-HSA-3000178 8.962790e-01 0.048 0 0
Pentose phosphate pathway R-HSA-71336 8.971851e-01 0.047 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 8.971851e-01 0.047 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 8.974057e-01 0.047 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.015680e-01 0.045 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.022942e-01 0.045 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 9.038272e-01 0.044 0 0
Generation of second messenger molecules R-HSA-202433 9.038272e-01 0.044 0 0
Tryptophan catabolism R-HSA-71240 9.038272e-01 0.044 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.042439e-01 0.044 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.076752e-01 0.042 0 0
Parasite infection R-HSA-9664407 9.076752e-01 0.042 0 0
Leishmania phagocytosis R-HSA-9664417 9.076752e-01 0.042 0 0
Synthesis of PA R-HSA-1483166 9.083676e-01 0.042 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 9.093403e-01 0.041 0 0
Maturation of spike protein R-HSA-9694548 9.100665e-01 0.041 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 9.119465e-01 0.040 0 0
Formation of the ureteric bud R-HSA-9830674 9.119465e-01 0.040 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.119465e-01 0.040 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 9.119465e-01 0.040 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 9.119465e-01 0.040 0 0
Intra-Golgi traffic R-HSA-6811438 9.159249e-01 0.038 0 0
Hemostasis R-HSA-109582 9.159994e-01 0.038 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.190299e-01 0.037 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.190299e-01 0.037 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 9.190299e-01 0.037 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.190299e-01 0.037 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 9.190299e-01 0.037 0 0
Interleukin-6 family signaling R-HSA-6783589 9.190299e-01 0.037 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.205433e-01 0.036 0 0
Peptide hormone metabolism R-HSA-2980736 9.208279e-01 0.036 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 9.214232e-01 0.036 0 0
Depyrimidination R-HSA-73928 9.214232e-01 0.036 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.214232e-01 0.036 0 0
tRNA Aminoacylation R-HSA-379724 9.232363e-01 0.035 0 0
Metabolism of polyamines R-HSA-351202 9.232363e-01 0.035 0 0
Cardiac conduction R-HSA-5576891 9.239486e-01 0.034 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.242965e-01 0.034 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.255439e-01 0.034 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 9.255439e-01 0.034 0 0
G protein gated Potassium channels R-HSA-1296059 9.255439e-01 0.034 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 9.255439e-01 0.034 0 0
Tight junction interactions R-HSA-420029 9.255439e-01 0.034 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.255439e-01 0.034 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.255439e-01 0.034 0 0
Fertilization R-HSA-1187000 9.255439e-01 0.034 0 0
Laminin interactions R-HSA-3000157 9.255439e-01 0.034 0 0
Platelet homeostasis R-HSA-418346 9.288706e-01 0.032 0 0
MET activates PTK2 signaling R-HSA-8874081 9.315342e-01 0.031 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 9.315342e-01 0.031 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.315342e-01 0.031 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 9.315342e-01 0.031 0 0
Sphingolipid catabolism R-HSA-9845614 9.315342e-01 0.031 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 9.315342e-01 0.031 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.337331e-01 0.030 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 9.348705e-01 0.029 0 0
Stimuli-sensing channels R-HSA-2672351 9.353054e-01 0.029 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.358646e-01 0.029 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.370429e-01 0.028 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.370429e-01 0.028 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 9.394636e-01 0.027 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.402027e-01 0.027 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.402027e-01 0.027 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 9.421086e-01 0.026 0 0
Telomere Extension By Telomerase R-HSA-171319 9.421086e-01 0.026 0 0
Leishmania infection R-HSA-9658195 9.454993e-01 0.024 0 0
Parasitic Infection Pathways R-HSA-9824443 9.454993e-01 0.024 0 0
Metabolism of proteins R-HSA-392499 9.458726e-01 0.024 1 0
Downstream signaling of activated FGFR3 R-HSA-5654708 9.467670e-01 0.024 0 0
Glucagon-type ligand receptors R-HSA-420092 9.467670e-01 0.024 0 0
Co-stimulation by CD28 R-HSA-389356 9.479105e-01 0.023 0 0
Post-translational protein modification R-HSA-597592 9.491043e-01 0.023 1 0
Kidney development R-HSA-9830369 9.497265e-01 0.022 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.510509e-01 0.022 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 9.510509e-01 0.022 0 0
Neurotransmitter clearance R-HSA-112311 9.510509e-01 0.022 0 0
Cargo concentration in the ER R-HSA-5694530 9.549902e-01 0.020 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.566720e-01 0.019 0 0
Meiotic recombination R-HSA-912446 9.577199e-01 0.019 0 0
Complex IV assembly R-HSA-9864848 9.577199e-01 0.019 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 9.582342e-01 0.019 0 0
Interferon alpha/beta signaling R-HSA-909733 9.582933e-01 0.019 0 0
Inwardly rectifying K+ channels R-HSA-1296065 9.586127e-01 0.018 0 0
Ion channel transport R-HSA-983712 9.605070e-01 0.017 0 0
Disease R-HSA-1643685 9.606001e-01 0.017 0 0
Adaptive Immune System R-HSA-1280218 9.614106e-01 0.017 0 0
Recycling of bile acids and salts R-HSA-159418 9.619439e-01 0.017 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 9.619439e-01 0.017 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.637950e-01 0.016 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.650071e-01 0.015 0 0
Activation of HOX genes during differentiation R-HSA-5619507 9.652314e-01 0.015 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 9.652314e-01 0.015 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.657449e-01 0.015 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.674855e-01 0.014 0 0
G alpha (z) signalling events R-HSA-418597 9.680782e-01 0.014 0 0
Paracetamol ADME R-HSA-9753281 9.680782e-01 0.014 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.704142e-01 0.013 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.704142e-01 0.013 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.704142e-01 0.013 0 0
Integration of energy metabolism R-HSA-163685 9.715874e-01 0.013 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.722078e-01 0.012 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.727960e-01 0.012 0 0
RUNX2 regulates bone development R-HSA-8941326 9.727960e-01 0.012 0 0
G1/S-Specific Transcription R-HSA-69205 9.727960e-01 0.012 0 0
Formation of the cornified envelope R-HSA-6809371 9.736082e-01 0.012 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.741947e-01 0.011 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.741947e-01 0.011 0 0
Mitochondrial protein degradation R-HSA-9837999 9.742405e-01 0.011 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.749863e-01 0.011 0 0
Lysine catabolism R-HSA-71064 9.749863e-01 0.011 0 0
Metabolism of folate and pterines R-HSA-196757 9.749863e-01 0.011 0 0
Triglyceride metabolism R-HSA-8979227 9.759694e-01 0.011 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.763427e-01 0.010 0 0
tRNA processing in the mitochondrion R-HSA-6785470 9.770003e-01 0.010 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.780053e-01 0.010 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.784255e-01 0.009 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.791983e-01 0.009 0 0
rRNA processing in the mitochondrion R-HSA-8868766 9.805552e-01 0.009 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.805552e-01 0.009 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 9.806130e-01 0.009 0 0
Heme signaling R-HSA-9707616 9.806130e-01 0.009 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.821211e-01 0.008 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.821211e-01 0.008 0 0
Mitochondrial biogenesis R-HSA-1592230 9.848408e-01 0.007 0 0
Innate Immune System R-HSA-168249 9.848530e-01 0.007 0 0
Activation of GABAB receptors R-HSA-991365 9.848850e-01 0.007 0 0
GABA B receptor activation R-HSA-977444 9.848850e-01 0.007 0 0
Defective pyroptosis R-HSA-9710421 9.861024e-01 0.006 0 0
Defensins R-HSA-1461973 9.861024e-01 0.006 0 0
Metabolism of steroid hormones R-HSA-196071 9.864865e-01 0.006 0 0
Amine ligand-binding receptors R-HSA-375280 9.872219e-01 0.006 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.872219e-01 0.006 0 0
COPII-mediated vesicle transport R-HSA-204005 9.891359e-01 0.005 1 1
Metabolism of cofactors R-HSA-8978934 9.899008e-01 0.004 0 0
Metabolism of porphyrins R-HSA-189445 9.899008e-01 0.004 0 0
Synthesis of PC R-HSA-1483191 9.900680e-01 0.004 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.908682e-01 0.004 0 0
Aspirin ADME R-HSA-9749641 9.912760e-01 0.004 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.913366e-01 0.004 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.914894e-01 0.004 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.916040e-01 0.004 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.917157e-01 0.004 0 0
Azathioprine ADME R-HSA-9748787 9.922805e-01 0.003 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.922805e-01 0.003 0 0
Cytosolic sulfonation of small molecules R-HSA-156584 9.929026e-01 0.003 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.934995e-01 0.003 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.939622e-01 0.003 0 0
Interleukin-10 signaling R-HSA-6783783 9.939622e-01 0.003 0 0
Nucleotide biosynthesis R-HSA-8956320 9.940005e-01 0.003 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.948325e-01 0.002 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.948675e-01 0.002 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.951675e-01 0.002 1 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.956798e-01 0.002 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.963288e-01 0.002 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.963288e-01 0.002 0 0
RAB geranylgeranylation R-HSA-8873719 9.966688e-01 0.001 0 0
GABA receptor activation R-HSA-977443 9.966688e-01 0.001 0 0
Endogenous sterols R-HSA-211976 9.969374e-01 0.001 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 9.971843e-01 0.001 0 0
Bacterial Infection Pathways R-HSA-9824439 9.971885e-01 0.001 0 0
Complex I biogenesis R-HSA-6799198 9.974114e-01 0.001 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.979885e-01 0.001 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.981154e-01 0.001 0 0
Nicotinate metabolism R-HSA-196807 9.981508e-01 0.001 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.985632e-01 0.001 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.986097e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.986791e-01 0.001 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.989331e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.990742e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.992646e-01 0.000 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 9.993613e-01 0.000 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 9.993613e-01 0.000 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 9.993613e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.994331e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.994821e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.995577e-01 0.000 0 0
G alpha (s) signalling events R-HSA-418555 9.995921e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.996814e-01 0.000 0 0
PPARA activates gene expression R-HSA-1989781 9.996940e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.997547e-01 0.000 0 0
Interferon gamma signaling R-HSA-877300 9.997674e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.998249e-01 0.000 0 0
G alpha (q) signalling events R-HSA-416476 9.998404e-01 0.000 0 0
Keratinization R-HSA-6805567 9.998484e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.998520e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.998626e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.998750e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.998750e-01 0.000 0 0
Potassium Channels R-HSA-1296071 9.998750e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.998944e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.998951e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999227e-01 0.000 0 0
PI Metabolism R-HSA-1483255 9.999246e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999273e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999389e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999441e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999616e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999676e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999693e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.999747e-01 0.000 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.999804e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999953e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999958e-01 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 9.999985e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999987e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999994e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999996e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.999998e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 1.000000e+00 0.000 0 0
Diseases of glycosylation R-HSA-3781865 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways