CHK1

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included

S Sites Probabilities

T Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Sites with acceptor types representing >8% and count ≥10 are included

Download Data Table

Motif clusters with count ≥ 10 are shown

Download

substrate_uniprot	site	source	substrate_genes	site_seq
A0A2R8Y4L2	S22	Sugiyama	HNRNPA1L3 HNRNPA1P48	SKSEsPKEPEQLRKLFIGGLsFEtTDESLRSHFEQWGTLTD
A0A2R8Y4L2	T25	Sugiyama	HNRNPA1L3 HNRNPA1P48	EsPKEPEQLRKLFIGGLsFEtTDESLRSHFEQWGTLTDCVV
A5A3E0	S1068	Sugiyama	POTEF A26C1B	SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
O00231	S298	Sugiyama	PSMD11	RYAGRQTEALKCVAQASKNRsLADFEKALTDYRAELRDDPI
O00273	S28	Sugiyama	DFFA DFF1 DFF45 H13	GVPESGEIRTLKPCLLRRNysREQHGVAAsCLEDLRSKACD
O00716	S124	SIGNOR\|EPSD\|PSP	E2F3 KIAA0075	HGPSSRAGLLQQPPALGRGGsGGGGGPPAKRRLELGESGHQ
O14618	S245	Sugiyama	CCS	LACGIIARSAGLFQNPKQICsCDGLTIWEERGRPIAGKGRK
O14757	S147	Sugiyama	CHEK1 CHK1	THRDIKPENLLLDERDNLKIsDFGLAtVFRYNNRERLLNKM
O14757	S280	Sugiyama	CHEK1 CHK1	KKDRWYNKPLKKGAKRPRVtsGGVsEsPsGFsKHIQsNLDF
O14757	S284	Sugiyama	CHEK1 CHK1	WYNKPLKKGAKRPRVtsGGVsEsPsGFsKHIQsNLDFsPVN
O14757	S286	Sugiyama	CHEK1 CHK1	NKPLKKGAKRPRVtsGGVsEsPsGFsKHIQsNLDFsPVNsA
O14757	S288	Sugiyama	CHEK1 CHK1	PLKKGAKRPRVtsGGVsEsPsGFsKHIQsNLDFsPVNsAss
O14757	S291	EPSD\|PSP\|Sugiyama	CHEK1 CHK1	KGAKRPRVtsGGVsEsPsGFsKHIQsNLDFsPVNsAssEEN
O14757	S296	SIGNOR\|EPSD\|PSP\|Sugiyama	CHEK1 CHK1	PRVtsGGVsEsPsGFsKHIQsNLDFsPVNsAssEENVKYss
O14757	S305	Sugiyama	CHEK1 CHK1	EsPsGFsKHIQsNLDFsPVNsAssEENVKYsssQPEPRTGL
O14757	S316	EPSD\|PSP	CHEK1 CHK1	sNLDFsPVNsAssEENVKYsssQPEPRTGLsLWDtsPsYID
O14757	S326	Sugiyama	CHEK1 CHK1	AssEENVKYsssQPEPRTGLsLWDtsPsYIDKLVQGISFsQ
O14757	S331	Sugiyama	CHEK1 CHK1	NVKYsssQPEPRTGLsLWDtsPsYIDKLVQGISFsQPTCPD
O14757	S333	Sugiyama	CHEK1 CHK1	KYsssQPEPRTGLsLWDtsPsYIDKLVQGISFsQPTCPDHM
O14757	S467	Sugiyama	CHEK1 CHK1	DGLEFKRHFLKIKGKLIDIVssQKIWLPAT___________
O14757	T153	Sugiyama	CHEK1 CHK1	PENLLLDERDNLKIsDFGLAtVFRYNNRERLLNKMCGtLPy
O14757	T170	Sugiyama	CHEK1 CHK1	GLAtVFRYNNRERLLNKMCGtLPyVAPELLKRREFHAEPVD
O14757	T279	Sugiyama	CHEK1 CHK1	IKKDRWYNKPLKKGAKRPRVtsGGVsEsPsGFsKHIQsNLD
O14757	T330	Sugiyama	CHEK1 CHK1	ENVKYsssQPEPRTGLsLWDtsPsYIDKLVQGISFsQPTCP
O14757	T378	PSP	CHEK1 CHK1	QLLGTPGSSQNPWQRLVKRMtRFFtKLDADKSyQCLKETCE
O14757	T382	PSP	CHEK1 CHK1	TPGSSQNPWQRLVKRMtRFFtKLDADKSyQCLKETCEKLGy
O14757	T413	Sugiyama	CHEK1 CHK1	LKETCEKLGyQWKKSCMNQVtISTTDRRNNKLIFKVNLLEM
O14757	Y173	Sugiyama	CHEK1 CHK1	tVFRYNNRERLLNKMCGtLPyVAPELLKRREFHAEPVDVWS
O14757	Y402	Sugiyama	CHEK1 CHK1	tKLDADKSyQCLKETCEKLGyQWKKSCMNQVtISTTDRRNN
O14974	S20	SIGNOR	PPP1R12A MBS MYPT1	_MKMADAKQKRNEQLKRWIGsEtDLEPPVVKRQKTKVKFDD
O15067	S215	Sugiyama	PFAS KIAA0361	LDSWDLDFYTKRFQELQRNPstVEAFDLAQsNsEHSRHWFF
O15151	S342	SIGNOR\|iPTMNet\|EPSD\|PSP	MDM4 MDMX	RCWALRKDWYSDCSKLtHsLstsDItAIPEKENEGNDVPDC
O15151	S367	SIGNOR\|iPTMNet\|EPSD\|PSP	MDM4 MDMX	tAIPEKENEGNDVPDCRRtIsAPVVRPKDAYIKKENSKLFD
O15226	S618	Sugiyama	NKRF ITBA4 NRF	VNKIAKRDIEQIIRNYARsEsHtDLtFsRELTNDERKQIHQ
O15294	S20	EPSD\|PSP	OGT	_MAssVGNVADSTEPTKRMLsFQGLAELAHREYQAGDFEAA
O15350	S47	SIGNOR\|ELM\|EPSD\|PSP	TP73 P73	tyFDLPQSSRGNNEVVGGTDssMDVFHLEGMTTSVMAQFNL
O43390	T429	Sugiyama	HNRNPR HNRPR	AKPPDKKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGR
O43390	Y431	Sugiyama	HNRNPR HNRPR	PPDKKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGR
O43395	S161	EPSD\|PSP	PRPF3 HPRP3 PRP3	QIKQMMEAATRQIEERKKQLsFIsPPtPQPKtPsssQPERL
O43660	S119	EPSD\|PSP	PLRG1	PYPPGPGVALTADTKIQRMPsEsAAQSLAVALPLQTKADAN
O43823	S323	Sugiyama	AKAP8 AKAP95	RKRKQFQLyEEPDtKLARVDsEGDFsENDDAAGDFRsGDEE
O43852	S44	Sugiyama	CALU	KKDRVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQL
O43852	S69	Sugiyama	CALU	HDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKDGFVt
O43852	T196	Sugiyama	CALU	FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD
O43852	T65	Sugiyama	CALU	FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD
O60343	S485	EPSD\|PSP	TBC1D4 AS160 KIAA0603	CERIEGLYPPRAKLVIQRHLssLtDNEQADIFERVQKMKPV
O60343	S588	EPSD\|PSP	TBC1D4 AS160 KIAA0603	tssLENIFSRGANRMRGRLGsVDsFERsNsLASEKDYsPGD
O60506	S359	Sugiyama	SYNCRIP HNRPQ NSAP1	VLFVRNLANtVTEEILEKAFsQFGKLERVKKLKDyAFIHFD
O60814	S39	Sugiyama	H2BC12 H2BFT HIRIP1 HIST1H2BK	VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
O60841	S182	Sugiyama	EIF5B IF2 KIAA0741	DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK
O60841	S183	Sugiyama	EIF5B IF2 KIAA0741	GsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKN
O75151	S929	EPSD\|PSP	PHF2 CENP-35 KIAA0662	RVGPSVPRQDRPVREGTRVAsIETGLAAAAAKLsQQEEQKS
O75461	S12	SIGNOR\|EPSD\|PSP	E2F6	_________MSQQRPARKLPsLLLDPTEETVRRRCRDPINV
O75461	S52	SIGNOR\|EPSD\|PSP	E2F6	VEGLLPSKIRINLEDNVQYVsMRKALKVKRPRFDVSLVYLT
O75494	S133	Sugiyama	SRSF10 FUSIP1 FUSIP2 SFRS13A TASR	yDRYRRSRSRSYERRRsRsRsFDyNYRRsYsPRNSRPTGRP
O75592	S3478	PSP	MYCBP2 KIAA0916 PAM	ETSPITDTDLAKRTVFQRSYsVVASEYDKQHSILPARVKAI
O94779	T494	Sugiyama	CNTN5	KILASAPTFALNQLKKTIIVtKDQEVVIECKPQGSPKPTIS
O95218	S181	Sugiyama	ZRANB2 ZIS ZNF265	DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR
O95625	S511	EPSD\|PSP	ZBTB11	TAKTDFGPDDDTYRSRLRQRsVNEGAYIRLHKGMEKKLQKR
O95625	S537	EPSD\|PSP	ZBTB11	YIRLHKGMEKKLQKRKAVPKsAVQQVAQKLVQRGKKMKQPK
O95707	S10	EPSD\|PSP	POP4 RPP29	___________MKSVIyHALsQKEANDsDVQPSGAQRAEAF
O95757	S599	Sugiyama	HSPA4L APG1 HSPH3 OSP94	sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND
O95785	S1129	EPSD\|PSP	WIZ ZNF803	ALAKMMGGAGPGssLEARsPsDLHIsPLAKKLPPPPGsPLG
O95816	S208	Sugiyama	BAG2	IKLLEHSKGAGSKTLQQNAEsRFN_________________
O95817	T124	Sugiyama	BAG3 BIS	ENRQVHPFHVYPQPGMQRFRtEAAAAAPQRsQsPLRGMPEt
P00338	S105	Sugiyama	LDHA PIG19	VTANsKLVIItAGARQQEGEsRLNLVQRNVNIFKFIIPNVV
P00338	S161	Sugiyama	LDHA PIG19	DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338	S167	Sugiyama	LDHA PIG19	AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00338	T322	Sugiyama	LDHA PIG19	DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00338	Y172	Sugiyama	LDHA PIG19	GFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHGWVLGE
P00491	S176	Sugiyama	PNP NP	GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA
P00558	Y161	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P02545	S307	EPSD\|PSP	LMNA LMN1	AAHEELQQsRIRIDsLsAQLsQLQKQLAAKEAKLRDLEDsL
P04075	S17	Sugiyama	ALDOA ALDA	____MPyQyPALtPEQKKELsDIAHRIVAPGKGILAADEst
P04075	S176	Sugiyama	ALDOA ALDA	EHtPsALAIMENANVLARyAsICQQNGIVPIVEPEILPDGD
P04075	S336	Sugiyama	ALDOA ALDA	GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075	S46	Sugiyama	ALDOA ALDA	PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04083	S189	Sugiyama	ANXA1 ANX1 LPC1	tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA
P04181	T33	Sugiyama	OAT	VLSRGVHSSVASATSVATKKtVQGPPtSDDIFEREyKyGAH
P04181	T39	Sugiyama	OAT	HSSVASATSVATKKtVQGPPtSDDIFEREyKyGAHNyHPLP
P04406	S241	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406	S312	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA
P04406	S321	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406	T237	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04637	S15	SIGNOR\|iPTMNet\|EPSD\|PSP	TP53 P53	______MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPL
P04637	S20	SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	TP53 P53	_MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQAM
P04637	S366	SIGNOR	TP53 P53	EALELKDAQAGKEPGGSRAHssHLKsKKGQstsRHKKLMFK
P04637	S37	SIGNOR\|iPTMNet\|EPSD\|PSP	TP53 P53	EtFsDLWKLLPENNVLsPLPsQAMDDLMLsPDDIEQWFtED
P04637	S378	SIGNOR\|EPSD\|PSP	TP53 P53	EPGGSRAHssHLKsKKGQstsRHKKLMFKtEGPDsD_____
P04637	T18	SIGNOR\|EPSD\|PSP	TP53 P53	___MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQ
P04637	T387	SIGNOR\|EPSD\|PSP	TP53 P53	sHLKsKKGQstsRHKKLMFKtEGPDsD______________
P04792	S187	Sugiyama	HSPB1 HSP27 HSP28	APMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAAK__
P04792	S78	Sugiyama	HSPB1 HSP27 HSP28	LPPAAIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVs
P04792	S82	Sugiyama	HSPB1 HSP27 HSP28	AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04792	S83	Sugiyama	HSPB1 HSP27 HSP28	IEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNH
P04792	S86	Sugiyama	HSPB1 HSP27 HSP28	PAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNHFAP
P04792	T174	Sugiyama	HSPB1 HSP27 HSP28	SSsLsPEGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGP
P04792	T184	Sugiyama	HSPB1 HSP27 HSP28	TVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAA
P05198	T279	Sugiyama	EIF2S1 EIF2A	KEKIEEKRGVFNVQMEPKVVtDtDEtELARQMERLERENAE
P05386	S101	Sugiyama	RPLP1 RRP1	APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386	S104	Sugiyama	RPLP1 RRP1	tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387	S102	Sugiyama	RPLP2 D11S2243E RPP2	PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387	S105	Sugiyama	RPLP2 D11S2243E RPP2	GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05388	S307	Sugiyama	RPLP0	AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
P05455	S94	Sugiyama	SSB	KSKAELMEIsEDKTKIRRsPsKPLPEVTDEyKNDVKNRsVY
P05455	T302	Sugiyama	SSB	ALGKAKDANNGNLQLRNKEVtWEVLEGEVEKEALKKIIEDQ
P05783	S93	Sugiyama	KRT18 CYK18 PIG46	GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR
P06400	S612	SIGNOR\|EPSD\|PSP	RB1	LNLPLQNNHtAADMyLsPVRsPKKKGSTTRVNstANAETQA
P06493	S208	EPSD\|PSP	CDK1 CDC2 CDC28A CDKN1 P34CDC2	WSIGTIFAELATKKPLFHGDsEIDQLFRIFRALGtPNNEVW
P06733	S291	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA
P06733	S37	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733	S40	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK
P06733	T205	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733	T41	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P07195	S106	Sugiyama	LDHB	VtANSKIVVVtAGVRQQEGEsRLNLVQRNVNVFKFIIPQIV
P07195	S162	Sugiyama	LDHB	DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195	S168	Sugiyama	LDHB	TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195	T323	Sugiyama	LDHB	sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205	Y161	Sugiyama	PGK2 PGKB	KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237	S427	Sugiyama	P4HB ERBA2L PDI PDIA1 PO4DB	WDKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFP
P07437	S115	Sugiyama	TUBB TUBB5 OK/SW-cl.56	sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437	T107	Sugiyama	TUBB TUBB5 OK/SW-cl.56	PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07602	S29	Sugiyama	PSAP GLBA SAP1	SLLGAALAGPVLGLKECtRGsAVWCQNVKTASDCGAVKHCL
P07814	S910	EPSD\|PSP	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	NsEPAGLEtPEAKVLFDKVAsQGEVVRKLKTEKAPKDQVDI
P07864	S161	Sugiyama	LDHC LDH3 LDHX	DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864	S167	Sugiyama	LDHC LDH3 LDHX	VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900	S53	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900	T317	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P07900	T467	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	LGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKEN
P07900	Y284	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI
P08238	S45	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238	S460	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ
P08238	S462	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238	S48	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238	T309	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238	T459	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	LGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEt
P08238	Y276	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI
P08631	Y411	EPSD\|PSP	HCK	ASLVCKIADFGLARVIEDNEytAREGAKFPIKWTAPEAINF
P08758	S116	Sugiyama	ANXA5 ANX5 ENX2 PP4	LKHALKGAGTNEKVLtEIIAsRtPEELRAIKQVyEEEyGss
P08758	T111	Sugiyama	ANXA5 ANX5 ENX2 PP4	yDAyELKHALKGAGTNEKVLtEIIAsRtPEELRAIKQVyEE
P09104	S37	Sugiyama	ENO2	NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09104	S40	Sugiyama	ENO2	VEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGK
P09104	T41	Sugiyama	ENO2	EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09382	T58	Sugiyama	LGALS1	DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09651	S22	Sugiyama	HNRNPA1 HNRPA1	sKsEsPKEPEQLRKLFIGGLsFEtTDESLRSHFEQWGTLTD
P09651	T25	Sugiyama	HNRNPA1 HNRPA1	EsPKEPEQLRKLFIGGLsFEtTDESLRSHFEQWGTLTDCVV
P09661	S226	Sugiyama	SNRPA1	NAIANAstLAEVERLKGLLQsGQIPGRERRsGPtDDGEEEM
P09972	S176	Sugiyama	ALDOC ALDC	ERTPSALAILENANVLARyAsICQQNGIVPIVEPEILPDGD
P0CG38	S1068	Sugiyama	POTEI	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39	S1031	Sugiyama	POTEJ	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DPH7	S48	Sugiyama	TUBA3C TUBA2	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7	S54	Sugiyama	TUBA3C TUBA2	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P10412	S55	Sugiyama	H1-4 H1F4 HIST1H1E	AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10412	S89	Sugiyama	H1-4 H1F4 HIST1H1E	AGyDVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNK
P10412	T92	Sugiyama	H1-4 H1F4 HIST1H1E	DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P11047	T258	EPSD\|PSP	LAMC1 LAMB2	PVLQEWVTATDIRVTLNRLNtFGDEVFNDPKVLKSYyyAIS
P11142	S85	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	NtVFDAKRLIGRRFDDAVVQsDMKHWPFMVVNDAGRPKVQV
P11142	T64	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11940	T191	Sugiyama	PABPC1 PAB1 PABP PABP1 PABPC2	GRFKSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLF
P11940	T379	Sugiyama	PABPC1 PAB1 PABP PABP1 PABPC2	AtKPLyVALAQRKEERQAHLtNQyMQRMASVRAVPNPVINP
P11940	Y194	Sugiyama	PABPC1 PAB1 PABP PABP1 PABPC2	KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF
P12268	S159	Sugiyama	IMPDH2 IMPD2	FCGIPITDtGRMGSRLVGIIssRDIDFLKEEEHDCFLEEIM
P12268	S416	Sugiyama	IMPDH2 IMPD2	APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK
P12931	S51	PSP	SRC SRC1	AFPAsQtPsKPAsADGHRGPsAAFAPAAAEPKLFGGFNssD
P12931	Y419	EPSD\|PSP	SRC SRC1	ENLVCKVADFGLARLIEDNEytARQGAKFPIKWTAPEAALy
P12931	Y530	EPSD\|PSP	SRC SRC1	PTFEYLQAFLEDyFtstEPQyQPGENL______________
P12956	S477	EPSD\|PSP	XRCC6 G22P1	EQVGKMKAIVEKLRFtYRsDsFENPVLQQHFRNLEALALDL
P13489	S178	Sugiyama	RNH1 PRI RNH	SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13639	S23	Sugiyama	EEF2 EF2	NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13861	S99	Sugiyama	PRKAR2A PKR2 PRKAR2	EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13929	S37	Sugiyama	ENO3	NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P13929	S40	Sugiyama	ENO3	VEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGK
P13929	T41	Sugiyama	ENO3	EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P14314	S126	Sugiyama	PRKCSH G19P1	yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14314	S451	Sugiyama	PRKCSH G19P1	KLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKyEQGtGC
P14314	S478	Sugiyama	PRKCSH G19P1	DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS
P14314	T444	Sugiyama	PRKCSH G19P1	VYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMK
P14618	S97	Sugiyama	PKM OIP3 PK2 PK3 PKM2	sHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGP
P14618	T95	Sugiyama	PKM OIP3 PK2 PK3 PKM2	NFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTK
P14625	S106	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625	S109	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625	S514	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK
P14625	S515	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	GVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQ
P14625	T150	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	EELTVKIKCDKEKNLLHVtDtGVGMtREELVKNLGTIAKsG
P14625	T155	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	KIKCDKEKNLLHVtDtGVGMtREELVKNLGTIAKsGtsEFL
P14625	T519	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	DHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIy
P14649	T101	Sugiyama	MYL6B MLC1SA	DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDELKSRR
P15531	S122	Sugiyama	NME1 NDPKA NM23	GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P15822	S1749	EPSD\|PSP	HIVEP1 ZNF40	ISVGRLsPQQEsSASSKRMLsPANsLDIAMEKHQKRAKDEN
P15880	T232	Sugiyama	RPS2 RPS4	KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P15880	T278	Sugiyama	RPS2 RPS4	EtVFtKsPyQEFtDHLVKtHtRVsVQRtQAPAVATt_____
P15880	T285	Sugiyama	RPS2 RPS4	PyQEFtDHLVKtHtRVsVQRtQAPAVATt____________
P16401	S92	Sugiyama	H1-5 H1F5 HIST1H1B	GGYDVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNK
P16401	T95	Sugiyama	H1-5 H1F5 HIST1H1B	DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16402	S56	Sugiyama	H1-3 H1F3 HIST1H1D	AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16402	S90	Sugiyama	H1-3 H1F3 HIST1H1D	AGyDVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNK
P16402	T93	Sugiyama	H1-3 H1F3 HIST1H1D	DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16403	S55	Sugiyama	H1-2 H1F2 HIST1H1C	AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403	S89	Sugiyama	H1-2 H1F2 HIST1H1C	AGyDVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNK
P16403	T92	Sugiyama	H1-2 H1F2 HIST1H1C	DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16989	T112	EPSD\|PSP	YBX3 CSDA DBPA	LGTVKWFNVRNGYGFINRNDtKEDVFVHQtAIKKNNPRKYL
P18124	T170	Sugiyama	RPL7	VNELIyKRGYGKINKKRIALtDNALIARSLGKyGIICMEDL
P18615	S115	Sugiyama	NELFE RD RDBP	KLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLyEs
P18615	S165	Sugiyama	NELFE RD RDBP	ELGPDGEEAEGPGAGDGPPRsFDWGyEERSGAHSsAsPPRs
P18621	S5	Sugiyama	RPL17	________________MVRysLDPENPtKsCKSRGSNLRVH
P18669	S14	Sugiyama	PGAM1 PGAMA CDABP0006	_______MAAYKLVLIRHGEsAWNLENRFsGWyDADLsPAG
P18669	S152	Sugiyama	PGAM1 PGAMA CDABP0006	FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669	S155	Sugiyama	PGAM1 PGAMA CDABP0006	NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18754	S90	Sugiyama	RCC1 CHC1	VQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsVEGSEM
P18858	S76	EPSD\|PSP	LIG1	PGRKAARVLGsEGEEEDEALsPAKGQKPALDCsQVsPPRPA
P19338	S356	Sugiyama	NCL	LAVVDVRIGMTRKFGyVDFEsAEDLEKALELtGLKVFGNEI
P19338	S532	Sugiyama	NCL	IKVPQNQNGKSKGyAFIEFAsFEDAKEALNSCNKREIEGRA
P19338	Y525	Sugiyama	NCL	VFEKATFIKVPQNQNGKSKGyAFIEFAsFEDAKEALNSCNK
P19838	S328	SIGNOR\|EPSD\|PSP	NFKB1	QFAIVFKTPKYKDINITKPAsVFVQLRRKsDLETSEPKPFL
P20042	S67	Sugiyama	EIF2S2 EIF2B	EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK
P20674	S104	Sugiyama	COX5A	PEPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYP
P21108	S11	Sugiyama	PRPS1L1 PRPS3 PRPSL	__________MPNIKIFsGssHQDLSQKIADRLGLELGKVV
P22090	S204	Sugiyama	RPS4Y1 RPS4Y PRO2646	IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN
P22090	T141	Sugiyama	RPS4Y1 RPS4Y PRO2646	YKLCKVRKITVGVKGIPHLVtHDARTIRYPDPVIKVNDTVQ
P22314	S46	Sugiyama	UBA1 A1S9T UBE1	AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA
P22626	S189	Sugiyama	HNRNPA2B1 HNRPA2B1	IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF
P22626	S225	Sugiyama	HNRNPA2B1 HNRPA2B1	GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P22626	T159	EPSD\|PSP	HNRNPA2B1 HNRPA2B1	DtIEIItDRQsGKKRGFGFVtFDDHDPVDKIVLQKyHtING
P23246	S283	Sugiyama	SFPQ PSF	GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23528	T63	Sugiyama	CFL1 CFL	DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23588	S122	Sugiyama	EIF4B	NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA
P23588	S131	Sugiyama	EIF4B	SIKEFFRGLNIsAVRLPREPsNPERLKGFGyAEFEDLDSLL
P23588	S207	Sugiyama	EIF4B	DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR
P23588	T205	Sugiyama	EIF4B	GRDRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYR
P25205	S160	EPSD\|PSP	MCM3	KVVRSVHYCPATKKTIERRysDLttLVAFPSSSVYPTKDEE
P26038	S527	Sugiyama	MSN	ERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHAE
P26038	S576	Sugiyama	MSN	YKtLRQIRQGNTKQRIDEFEsM___________________
P26038	T526	Sugiyama	MSN	EERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHA
P26373	S181	Sugiyama	RPL13 BBC1 OK/SW-cl.46	YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373	T107	Sugiyama	RPL13 BBC1 OK/SW-cl.46	HKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILF
P26373	T148	Sugiyama	RPL13 BBC1 OK/SW-cl.46	PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373	T151	Sugiyama	RPL13 BBC1 OK/SW-cl.46	PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26373	T170	EPSD\|PSP	RPL13 BBC1 OK/SW-cl.46	LtGPVMPVRNVYKKEKARVItEEEKNFKAFAsLRMARANAR
P26447	S60	Sugiyama	S100A4 CAPL MTS1	RELPSFLGKRTDEAAFQKLMsNLDSNRDNEVDFQEYCVFLS
P27708	S1859	Sugiyama	CAD	RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP
P27797	S35	Sugiyama	CALR CRTC	AVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGK
P27797	S40	Sugiyama	CALR CRTC	AVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGKFyGDE
P27797	S52	Sugiyama	CALR CRTC	GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27816	T521	SIGNOR	MAP4	GLLKDMsPLsEtEMALGKDVtPPPEtEVVLIKNVCLPPEME
P27816	T925	EPSD\|PSP	MAP4	DKKPTSAKPssttPRLSRLAtNtsAPDLKNVRsKVGstENI
P27824	S554	Sugiyama	CANX	EKDKGDEEEEGEEKLEEKQKsDAEEDGGtVsQEEEDRKPKA
P29401	S105	Sugiyama	TKT	VWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGsL
P29401	S332	Sugiyama	TKT	GDKIATRKAYGQALAKLGHAsDRIIALDGDtKNstFsEIFK
P29401	T442	Sugiyama	TKT	GEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAA
P29692	S60	Sugiyama	EEF1D EF1D	ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL
P29692	S64	Sugiyama	EEF1D EF1D	sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI
P29692	S86	Sugiyama	EEF1D EF1D	GPGAssGtsGDHGELVVRIAsLEVENQsLRGVVQELQQAIs
P29692	T129	Sugiyama	EEF1D EF1D	EARLNVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPA
P30043	T190	Sugiyama	BLVRB FLR SCAN	RGPSRVISKHDLGHFMLRCLttDEyDGHstyPsHQyQ____
P30050	S138	Sugiyama	RPL12	HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050	S157	Sugiyama	RPL12	QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P30085	S180	Sugiyama	CMPK1 CMK CMPK UCK UMK UMPK	KPIIDLyEEMGKVKKIDASKsVDEVFDEVVQIFDKEG____
P30086	S139	Sugiyama	PEBP1 PBP PEBP	RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE
P30086	S52	Sugiyama	PEBP1 PBP PEBP	AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30086	T167	Sugiyama	PEBP1 PBP PEBP	GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK
P30101	S474	Sugiyama	PDIA3 ERP57 ERP60 GRP58	yFsPANKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEK
P30101	S478	Sugiyama	PDIA3 ERP57 ERP60 GRP58	ANKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKK
P30101	S98	Sugiyama	PDIA3 ERP57 ERP60 GRP58	VPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGP
P30101	T102	Sugiyama	PDIA3 ERP57 ERP60 GRP58	KVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRtAD
P30101	T485	Sugiyama	PDIA3 ERP57 ERP60 GRP58	KKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKKKKAQEDL
P30101	Y100	Sugiyama	PDIA3 ERP57 ERP60 GRP58	LAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRt
P30304	S124	SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CDC25A	RIHsLPQKLLGCsPALKRSHsDSLDHDIFQLIDPDENKENE
P30304	S178	SIGNOR\|ELM\|EPSD\|PSP	CDC25A	GCLHSHGLQEGKDLFTQRQNsAPARMLsSNERDSSEPGNFI
P30304	S239	iPTMNet	CDC25A	VDLLDGENLKNEEETPSCMAsLWTAPLVMRTTNLDNRCKLF
P30304	S279	SIGNOR\|ELM\|EPSD\|PSP	CDC25A	FDsPsLCssSTRSVLKRPERsQEEsPPGSTKRRKsMsGASP
P30304	S293	SIGNOR\|ELM\|EPSD\|PSP	CDC25A	LKRPERsQEEsPPGSTKRRKsMsGASPKESTNPEKAHETLH
P30304	S76	SIGNOR\|ELM\|EPSD\|PSP	CDC25A	GSDyEQPLEVKNNSNLQRMGsSEstDsGFCLDsPGPLDSKE
P30304	T507	SIGNOR\|ELM\|EPSD\|PSP	CDC25A	RPMHHEDFKEDLKKFRTKSRtWAGEKsKREMYsRLKKL___
P30305	S230	SIGNOR\|ELM\|EPSD\|PSP	CDC25B CDC25HU2	STHALAEWAsRREAFAQRPssAPDLMCLsPDRKMEVEELsP
P30305	S563	EPSD\|PSP	CDC25B CDC25HU2	RPMNHEAFKDELKTFRLKTRsWAGERSRRELCSRLQDQ___
P30307	S216	SIGNOR\|iPTMNet\|EPSD\|PSP	CDC25C	EFsLKDQEAKVSRsGLYRsPsMPENLNRPRLKQVEKFKDNt
P30533	S230	Sugiyama	LRPAP1 A2MRAP	SDIKGSVLHSRHTELKEKLRsINQGLDRLRRVsHQGystEA
P30533	T134	Sugiyama	LRPAP1 A2MRAP	NLNVILAKYGLDGKKDARQVtsNsLsGtQEDGLDDPRLEKL
P30533	T248	Sugiyama	LRPAP1 A2MRAP	LRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWDLAQSAN
P30533	Y246	Sugiyama	LRPAP1 A2MRAP	EKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWDLAQS
P31327	S564	Sugiyama	CPS1	TEDRQLFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPV
P31327	S569	Sugiyama	CPS1	LFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPVMIRSA
P31327	S835	Sugiyama	CPS1	MCHPsIEGFTPRLPMNKEWPsNLDLRKELSEPSsTRIyAIA
P31327	T45	Sugiyama	CPS1	AHQKWKFSRPGIRLLSVKAQtAHIVLEDGtKMKGYSFGHPS
P31948	Y354	Sugiyama	STIP1	DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG
P32119	T142	Sugiyama	PRDX2 NKEFB TDPX1	EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF
P33991	S54	GPS6\|ELM\|EPSD	MCM4 CDC21	sQRRRGEDSTSTGELQPMPtsPGVDLQSPAAQDVLFSsPPQ
P33992	T633	EPSD\|PSP	MCM5 CDC46	LEAIVRIAEALSKMKLQPFAtEADVEEALRLFQVSTLDAAL
P34932	S363	Sugiyama	HSPA4 APG2 HSPH2	GATRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAIL
P34932	S76	Sugiyama	HSPA4 APG2 HSPH2	VISNAKNTVQGFKRFHGRAFsDPFVEAEKSNLAYDIVQLPT
P35269	T154	Sugiyama	GTF2F1 RAP74	AFEAFPVHNWYNFTPLARHRtLtAEEAEEEWERRNKVLNHF
P35579	S1304	Sugiyama	MYH9	NVtGLLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQK
P35579	S1308	Sugiyama	MYH9	LLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLs
P35579	S1915	Sugiyama	MYH9	KLQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMA
P35579	T1906	Sugiyama	MYH9	AQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRGDL
P35611	S726	EPSD\|PSP	ADD1 ADDA	GsDGSPGKSPsKKKKKFRtPsFLKKSKKKSDS_________
P35612	S713	EPSD\|PSP	ADD2 ADDB	sPEGsPsKsPsKKKKKFRTPsFLKKSKKKEKVEs_______
P35637	S462	Sugiyama	FUS TLS	NECNQCKAPKPDGPGGGPGGsHMGGNyGDDRRGGRGGYDRG
P36507	T59	EPSD\|PSP	MAP2K2 MEK2 MKK2 PRKMK2	KKLEELELDEQQKKRLEAFLtQKAKVGELKDDDFERIsELG
P36578	S272	Sugiyama	RPL4 RPL1	WtEsAFRKLDELyGtWRKAAsLKsNyNLPMHKMINtDLsRI
P36578	S275	Sugiyama	RPL4 RPL1	sAFRKLDELyGtWRKAAsLKsNyNLPMHKMINtDLsRILKs
P36578	S365	Sugiyama	RPL4 RPL1	RNHKLRVDKAAAAAAALQAKsDEKAAVAGKKPVVGKKGKKA
P36578	S55	Sugiyama	RPL4 RPL1	DIVNFVHTNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVAR
P36578	S63	Sugiyama	RPL4 RPL1	NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG
P36578	S87	Sugiyama	RPL4 RPL1	WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578	T62	Sugiyama	RPL4 RPL1	TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578	T84	Sugiyama	RPL4 RPL1	AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P36578	Y277	Sugiyama	RPL4 RPL1	FRKLDELyGtWRKAAsLKsNyNLPMHKMINtDLsRILKsPE
P37108	T45	Sugiyama	SRP14	sVyItLKKYDGRTKPIPKKGtVEGFEPADNKCLLRATDGKK
P37802	S163	Sugiyama	TAGLN2 KIAA0120 CDABP0035	LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802	S185	Sugiyama	TAGLN2 KIAA0120 CDABP0035	NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______
P37802	T180	Sugiyama	TAGLN2 KIAA0120 CDABP0035	RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802	T190	Sugiyama	TAGLN2 KIAA0120 CDABP0035	GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P38646	S549	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	IVHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYA
P38646	S554	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	AKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYAEEDRR
P38646	S89	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646	T116	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646	T398	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646	T94	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P39019	S59	Sugiyama	RPS19	LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY
P39019	S93	Sugiyama	RPS19	GsMTKIYGGRQRNGVMPsHFsRGsKsVARRVLQALEGLKMV
P39019	T55	Sugiyama	RPS19	DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM
P39019	Y54	Sugiyama	RPS19	VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023	S13	Sugiyama	RPL3 OK/SW-cl.32	________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023	S265	Sugiyama	RPL3 OK/SW-cl.32	HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P39023	T305	Sugiyama	RPL3 OK/SW-cl.32	YKIGQGyLIKDGKLIKNNAstDyDLSDKSINPLGGFVHYGE
P39748	S255	Sugiyama	FEN1 RAD2	CESIRGIGPKRAVDLIQKHKsIEEIVRRLDPNKYPVPENWL
P39748	T195	EPSD\|PSP	FEN1 RAD2	AATEDMDCLTFGsPVLMRHLtASEAKKLPIQEFHLsRILQE
P40227	S301	Sugiyama	CCT6A CCT6 CCTZ	VCGDSDKGFVVINQKGIDPFsLDALsKEGIVALRRAKRRNM
P40227	S306	Sugiyama	CCT6A CCT6 CCTZ	DKGFVVINQKGIDPFsLDALsKEGIVALRRAKRRNMERLTL
P40429	T153	Sugiyama	RPL13A	RKFAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQ
P40429	T155	Sugiyama	RPL13A	FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P40926	S309	Sugiyama	MDH2	sTPLLLGKKGIEKNLGIGKVssFEEKMIsDAIPELKASIKK
P40926	S310	Sugiyama	MDH2	TPLLLGKKGIEKNLGIGKVssFEEKMIsDAIPELKASIKKG
P41236	T22	Sugiyama	PPP1R2 IPP2	AASTAsHRPIKGILKNKtsttssMVAsAEQPRGNVDEELSK
P43034	S152	Sugiyama	PAFAH1B1 LIS1 MDCR MDS PAFAHA	IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM
P43243	S188	Sugiyama	MATR3 KIAA0723	EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P43243	S195	EPSD\|PSP	MATR3 KIAA0723	RDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyD
P43243	S4	EPSD\|PSP	MATR3 KIAA0723	_________________MsKsFQQssLsRDsQGHGRDLsAA
P43243	T150	EPSD\|PSP	MATR3 KIAA0723	EDKItPENLPQILLQLKRRRtEEGPtLsyGRDGRsAtREPP
P43405	S295	SIGNOR\|EPSD\|PSP	SYK	QLPGSHPATWSAGGIISRIKsysFPKPGHRKssPAQGNRQE
P43487	S60	Sugiyama	RANBP1	TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P43490	S472	Sugiyama	NAMPT PBEF PBEF1	EYGQDLLHTVFKNGKVTKsysFDEIRKNAQLNIELEAAHH_
P46013	T1764	EPSD\|PSP	MKI67	LVDtPtssKPQPKRSLRKADtEEEFLAFRKQTPSAGKAMHt
P46776	S68	Sugiyama	RPL27A	yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46776	Y52	Sugiyama	RPL27A	RGNAGGLHHHRINFDKyHPGyFGKVGMKHYHLKRNQsFCPt
P46777	S172	Sugiyama	RPL5 MSTP030	RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777	S176	Sugiyama	RPL5 MSTP030	GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777	S224	Sugiyama	RPL5 MSTP030	VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46777	Y210	Sugiyama	RPL5 MSTP030	FNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyIKNs
P46783	S146	Sugiyama	RPS10	TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P47914	S142	Sugiyama	RPL29	KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___
P47914	Y98	Sugiyama	RPL29	PKEVKPKIPKGVSRKLDRLAyIAHPKLGKRARARIAKGLRL
P48730	S181	GPS6	CSNK1D HCKID	tHQHIPYRENKNLtGtARYAsINtHLGIEQsRRDDLESLGY
P48730	T161	GPS6	CSNK1D HCKID	KGNLVyIIDFGLAKKyRDARtHQHIPYRENKNLtGtARYAs
P48730	T174	GPS6	CSNK1D HCKID	KKyRDARtHQHIPYRENKNLtGtARYAsINtHLGIEQsRRD
P48730	T176	GPS6	CSNK1D HCKID	yRDARtHQHIPYRENKNLtGtARYAsINtHLGIEQsRRDDL
P49327	S265	Sugiyama	FASN FAS	TILNAGTNTDGFKEQGVtFPsGDIQEQLIRSLyQsAGVAPE
P49327	T2215	Sugiyama	FASN FAS	DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN
P49588	S775	Sugiyama	AARS1 AARS	VTGAEAQKALRKAESLKKCLsVMEAKVKAQTAPNKDVQREI
P49790	S297	EPSD\|PSP	NUP153	KLRNtPYQAPVRRQMKAKQLsAQSYGVTSstARRILQsLEK
P49790	S330	EPSD\|PSP	NUP153	RILQsLEKMSsPLADAKRIPsIVssPLNsPLDRsGIDItDF
P49792	T1098	EPSD\|PSP	RANBP2 NUP358	GDGYsGAKPIPGGQTIGPRNtFNFGSKNVsGIsFtENMGss
P50454	S132	Sugiyama	SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14	GELLRSLSNSTARNVTWKLGsRLyGPssVsFADDFVRssKQ
P50454	S138	Sugiyama	SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14	LSNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEH
P50454	S139	Sugiyama	SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14	SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS
P50454	S141	Sugiyama	SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14	STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI
P50454	Y135	Sugiyama	SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14	LRSLSNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYN
P50914	S16	Sugiyama	RPL14	_____MVFRRFVEVGRVAyVsFGPHAGKLVAIVDVIDQNRA
P50990	S23	Sugiyama	CCT8 C21orf112 CCTQ KIAA0002	LHVPKAPGFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTT
P51587	T3387	GPS6\|EPSD	BRCA2 FACD FANCD1	ESTRTAPTSSEDYLRLKRRCtTSLIKEQESSQASTEECEKN
P51858	S69	Sugiyama	HDGF HMG1L2	FFGTHETAFLGPKDLFPyEEsKEKFGKPNKRKGFsEGLWEI
P52272	S432	EPSD\|PSP	HNRNPM HNRPM NAGR1	GGAGMERMGAGLGHGMDRVGsEIERMGLVMDRMGsVERMGs
P52292	S54	EPSD\|PSP	KPNA2 RCH1 SRP1	VNVELRKAKKDDQMLKRRNVssFPDDAtsPLQENRNNQGtV
P52294	S18	EPSD\|PSP	KPNA1 RCH2	___MttPGKENFRLKSYKNKsLNPDEMRRRREEEGLQLRKQ
P53350	S137	PSP	PLK1 PLK	HGFFEDNDFVFVVLELCRRRsLLELHKRRKALTEPEARYYL
P53350	S529	SIGNOR	PLK1 PLK	PYLRTWFRTRSAIILHLSNGsVQINFFQDHtKLILCPLMAA
P53350	T210	PSP	PLK1 PLK	VKIGDFGLATKVEYDGERKKtLCGtPNyIAPEVLSKKGHSF
P53350	T539	SIGNOR	PLK1 PLK	SAIILHLSNGsVQINFFQDHtKLILCPLMAAVTYIDEKRDF
P53396	S455	Sugiyama	ACLY	ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP
P53396	S656	Sugiyama	ACLY	IGNTGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISR
P53999	S118	Sugiyama	SUB1 PC4 RPO2TC1	PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________
P54132	S502	PSP	BLM RECQ2 RECQL3	TRKNLFERPLFNTHLQKsFVsSNWAEtPRLGKKNEsSYFPG
P54132	S539	EPSD\|PSP	BLM RECQ2 RECQL3	YFPGNVLtstAVKDQNKHTAsINDLERETQPSYDIDNFDID
P54132	S646	SIGNOR\|EPSD\|PSP	BLM RECQ2 RECQL3	YTDKSAQNLASRNLKHERFQsLSFPHTKEMMKIFHKKFGLH
P54132	T182	SIGNOR\|EPSD\|PSP	BLM RECQ2 RECQL3	TSETSKsFVtPPQsHFVRVStAQKSKKGKRNFFKAQLYTTN
P55039	S72	EPSD\|PSP	DRG2	GEGFDVMKSGDARVALIGFPsVGKSTFLSLMTSTASEAASY
P55735	S184	Sugiyama	SEC13 D3S1231E SEC13A SEC13L1 SEC13R	PGsLIDHPSGQKPNYIKRFAsGGCDNLIKLWKEEEDGQWKE
P57053	S39	Sugiyama	H2BC12L H2BFS H2BS1	VTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
P58876	S39	Sugiyama	H2BC5 H2BFB HIRIP2 HIST1H2BD	VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
P60174	S198	Sugiyama	TPI1 TPI	TPQQAQEVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtC
P60174	S212	Sugiyama	TPI1 TPI	WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174	T217	Sugiyama	TPI1 TPI	VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60660	T44	Sugiyama	MYL6	DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDEMNVKV
P60709	S199	Sugiyama	ACTB	DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709	S323	Sugiyama	ACTB	ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709	S368	Sugiyama	ACTB	sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709	S52	Sugiyama	ACTB	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709	S60	Sugiyama	ACTB	HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709	T201	Sugiyama	ACTB	AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709	T202	Sugiyama	ACTB	GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P60709	T318	Sugiyama	ACTB	VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709	T324	Sugiyama	ACTB	tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709	Y53	Sugiyama	ACTB	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P60891	S11	Sugiyama	PRPS1	__________MPNIKIFsGssHQDLSQKIADRLGLELGKVV
P61221	Y594	Sugiyama	ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40	RPRINKLNsIKDVEQKKsGNyFFLDD_______________
P61247	S236	Sugiyama	RPS3A FTE1 MFTL	KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61254	T8	Sugiyama	RPL26	_____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61313	S100	Sugiyama	RPL15 EC45 TCBAP0781	tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW
P61313	S118	Sugiyama	RPL15 EC45 TCBAP0781	LQsVAEERAGRHCGALRVLNsyWVGEDSTyKFFEVILIDPF
P61353	S86	Sugiyama	RPL27	SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL
P61978	S75	Sugiyama	HNRNPK HNRPK	GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61978	Y72	Sugiyama	HNRNPK HNRPK	KNAGAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISA
P62081	S174	Sugiyama	RPS7	IKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEFQL
P62081	T172	Sugiyama	RPS7	RLIKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEF
P62241	S160	Sugiyama	RPS8 OK/SW-cl.83	KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62241	S4	Sugiyama	RPS8 OK/SW-cl.83	_________________MGIsRDNWHKRRKTGGKRKPYHKK
P62249	S9	Sugiyama	RPS16	____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258	S148	Sugiyama	YWHAE	YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62263	S137	Sugiyama	RPS14 PRO2640	RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______
P62266	S45	Sugiyama	RPS23	KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62273	Y7	Sugiyama	RPS29	______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277	S12	Sugiyama	RPS13	_________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62280	T15	Sugiyama	RPS11	______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR
P62280	T54	Sugiyama	RPS11	PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62316	T40	Sugiyama	SNRPD2 SNRPD1	EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD
P62701	S204	Sugiyama	RPS4X CCG2 RPS4 SCAR	tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN
P62701	T141	Sugiyama	RPS4X CCG2 RPS4 SCAR	YKLCKVRKIFVGTKGIPHLVtHDARTIRYPDPLIKVNDtIQ
P62736	S325	Sugiyama	ACTA2 ACTSA ACTVS GIG46	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736	S54	Sugiyama	ACTA2 ACTSA ACTVS GIG46	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736	S62	Sugiyama	ACTA2 ACTSA ACTVS GIG46	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736	T320	Sugiyama	ACTA2 ACTSA ACTVS GIG46	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736	T326	Sugiyama	ACTA2 ACTSA ACTVS GIG46	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736	Y55	Sugiyama	ACTA2 ACTSA ACTVS GIG46	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62753	S53	Sugiyama	RPS6 OK/SW-cl.2	AtEVAADALGEEWKGYVVRIsGGNDKQGFPMKQGVLTHGRV
P62807	S39	Sugiyama	H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI	VTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKA
P62826	T32	Sugiyama	RAN ARA24 OK/SW-cl.81	KLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGVEVHPLVF
P62899	S15	Sugiyama	RPL31	______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG
P62899	T104	Sugiyama	RPL31	IRVRLSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDE
P62899	T107	Sugiyama	RPL31	RLSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN__
P62899	T112	Sugiyama	RPL31	RNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN_______
P62899	T22	Sugiyama	RPL31	APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899	T26	Sugiyama	RPL31	KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62899	Y108	Sugiyama	RPL31	LSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN___
P62906	S113	Sugiyama	RPL10A NEDD6	LNKNKKLVKKLAKKyDAFLAsEsLIKQIPRILGPGLNKAGK
P62906	S115	Sugiyama	RPL10A NEDD6	KNKKLVKKLAKKyDAFLAsEsLIKQIPRILGPGLNKAGKFP
P62917	S130	Sugiyama	RPL8	GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917	S138	Sugiyama	RPL8	EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI
P62917	S14	Sugiyama	RPL8	_______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917	T135	Sugiyama	RPL8	CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917	Y133	Sugiyama	RPL8	VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937	S51	Sugiyama	PPIA CYPA	KtAENFRALSTGEKGFGYKGsCFHRIIPGFMCQGGDFtRHN
P62979	S123	Sugiyama	RPS27A UBA80 UBCEP1	LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK
P62979	S134	Sugiyama	RPS27A UBA80 UBCEP1	IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P63104	S145	Sugiyama	YWHAZ	YYRyLAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHP
P63104	S156	Sugiyama	YWHAZ	DDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLGLALNFSV
P63104	Y149	Sugiyama	YWHAZ	LAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLG
P63173	T14	Sugiyama	RPL38	_______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63220	S65	Sugiyama	RPS21	RFNGQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF__
P63261	S199	Sugiyama	ACTG1 ACTG	DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261	S323	Sugiyama	ACTG1 ACTG	ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261	S368	Sugiyama	ACTG1 ACTG	sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261	S52	Sugiyama	ACTG1 ACTG	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261	S60	Sugiyama	ACTG1 ACTG	HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261	T201	Sugiyama	ACTG1 ACTG	AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261	T202	Sugiyama	ACTG1 ACTG	GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P63261	T318	Sugiyama	ACTG1 ACTG	VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261	T324	Sugiyama	ACTG1 ACTG	tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261	Y53	Sugiyama	ACTG1 ACTG	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267	S324	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267	S53	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267	S61	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267	T319	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267	T325	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267	Y54	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809	S102	Sugiyama	YBX1 NSEP1 YB1	EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809	S209	Sugiyama	YBX1 NSEP1 YB1	RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ
P67809	T108	Sugiyama	YBX1 NSEP1 YB1	QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809	T80	EPSD\|PSP\|Sugiyama	YBX1 NSEP1 YB1	LGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIKKNNPRKyL
P67809	Y99	Sugiyama	YBX1 NSEP1 YB1	DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P67870	T213	EPSD\|PSP	CSNK2B CK2N G5A	HPMAYQLQLQAAsNFKsPVKtIR__________________
P68032	S325	Sugiyama	ACTC1 ACTC	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032	S54	Sugiyama	ACTC1 ACTC	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032	S62	Sugiyama	ACTC1 ACTC	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032	T320	Sugiyama	ACTC1 ACTC	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032	T326	Sugiyama	ACTC1 ACTC	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032	Y55	Sugiyama	ACTC1 ACTC	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104	T23	Sugiyama	EEF1A1 EEF1A EF1A LENG7	KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
P68133	S325	Sugiyama	ACTA1 ACTA	TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133	S54	Sugiyama	ACTA1 ACTA	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133	S62	Sugiyama	ACTA1 ACTA	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133	T320	Sugiyama	ACTA1 ACTA	VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133	T326	Sugiyama	ACTA1 ACTA	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133	Y55	Sugiyama	ACTA1 ACTA	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363	S48	Sugiyama	TUBA1B	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363	S54	Sugiyama	TUBA1B	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P68363	T73	Sugiyama	TUBA1B	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363	T80	Sugiyama	TUBA1B	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363	T82	Sugiyama	TUBA1B	VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68363	Y83	Sugiyama	TUBA1B	PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P68431	T12	GPS6\|EPSD	H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J	_________MARtKQtARKstGGKAPRKQLATKAARKsAPA
P68431	T46	Sugiyama	H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J	ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P83731	S38	Sugiyama	RPL24	GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731	S7	Sugiyama	RPL24	______________MKVELCsFsGyKIYPGHGRRYARTDGK
P83731	S86	Sugiyama	RPL24	EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731	T83	Sugiyama	RPL24	QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
P84098	S12	EPSD\|PSP\|Sugiyama	RPL19	_________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI
P84098	S122	Sugiyama	RPL19	LRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHI
P84098	S13	Sugiyama	RPL19	________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEIA
P84098	S37	Sugiyama	RPL19	CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098	T29	Sugiyama	RPL19	RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P84098	T56	EPSD\|PSP	RPL19	NsRQQIRKLIKDGLIIRKPVtVHsRARCRKNTLARRKGRHM
P84098	Y124	Sugiyama	RPL19	RLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHIHK
P84243	S32	EPSD	H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B	tGGKAPRKQLATKAARKsAPsTGGVKKPHRyRPGtVALREI
P84243	T12	SIGNOR	H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B	_________MARtKQTARKstGGKAPRKQLATKAARKsAPs
P84243	T46	Sugiyama	H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B	ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P85299	S240	EPSD\|PSP	PRR5 PROTOR1 PP610	SEGPFTHSCILEKRLLRRsRsGDVLAKNPVVRsKsYNtPLL
Q00341	T8	EPSD\|PSP	HDLBP HBP VGL	_____________MssVAVLtQEsFAEHRSGLVPQQIKVAt
Q00610	S147	Sugiyama	CLTC CLH17 CLTCL2 KIAA0034	VYHWSMEGESQPVKMFDRHssLAGCQIINYRTDAKQKWLLL
Q01105	S161	Sugiyama	SET	FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01105	S168	Sugiyama	SET	ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01650	S31	Sugiyama	SLC7A5 CD98LC LAT1 MPE16	LAAPAAEEKEEAREKMLAAKsADGsAPAGEGEGVtLQRNIT
Q02539	S92	Sugiyama	H1-1 H1F1 HIST1H1A	AGyDVEKNNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNK
Q02539	T95	Sugiyama	H1-1 H1F1 HIST1H1A	DVEKNNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKAS
Q02543	S123	Sugiyama	RPL18A	AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK
Q02543	T101	Sugiyama	RPL18A	WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA
Q02543	T107	Sugiyama	RPL18A	RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02543	Y97	Sugiyama	RPL18A	NFGIWLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARH
Q02750	T55	EPSD\|PSP	MAP2K1 MEK1 PRKMK1	KKLEELELDEQQRKRLEAFLtQKQKVGELKDDDFEKIsELG
Q02878	T213	Sugiyama	RPL6 TXREB1	FVIAtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIF
Q04206	T505	EPSD\|PSP	RELA NFKB3	APHTTEPMLMEYPEAITRLVtGAQRPPDPAPAPLGAPGLPN
Q04837	S67	EPSD\|PSP	SSBP1 SSBP	QVEGKNPVTIFSLATNEMWRsGDsEVyQLGDVsQKTTWHRI
Q04917	T31	Sugiyama	YWHAH YWHA1	ARLAEQAERyDDMAsAMKAVtELNEPLsNEDRNLLsVAyKN
Q05639	T23	Sugiyama	EEF1A2 EEF1AL STN	KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
Q06609	T309	SIGNOR\|EPSD\|PSP	RAD51 RAD51A RECA	GNIIAHASTTRLYLRKGRGEtRICKIyDSPCLPEAEAMFAI
Q06830	S152	Sugiyama	PRDX1 PAGA PAGB TDPX2	IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV
Q06830	T143	Sugiyama	PRDX1 PAGA PAGB TDPX2	EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF
Q06830	T156	Sugiyama	PRDX1 PAGA PAGB TDPX2	KGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEVCPAG
Q07020	S140	Sugiyama	RPL18	ILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAPGtPH
Q07020	S41	Sugiyama	RPL18	QDIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRPPL
Q07020	T136	Sugiyama	RPL18	AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07020	T42	Sugiyama	RPL18	DIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRPPLs
Q07666	S20	Sugiyama	KHDRBS1 SAM68	_MQRRDDPAARMsRssGRsGsMDPsGAHPsVRQtPsRQPPL
Q07955	S182	Sugiyama	SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3	FVRKEDMTYAVRKLDNTKFRsHEGEtAyIRVKVDGPRsPsy
Q08AD1	S464	EPSD\|PSP	CAMSAP2 CAMSAP1L1 KIAA1078	FDKEDSVQRstPNRGITRsIsNEGLtLNNsHVsKHIRKNLS
Q08J23	S593	Sugiyama	NSUN2 SAKI TRM4	NNSEKMKVINTGIKVWCRNNsGEEFDCAFRLAQEGIYTLYP
Q09028	S146	Sugiyama	RBBP4 RBAP48	EVNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGE
Q12789	S667	EPSD\|PSP	GTF3C1	QEGVSTKCCKKSIVRLVRNLsEEGLLRLYRTTVIQDGIKKK
Q12888	S1678	EPSD\|PSP	TP53BP1	RAsMGVLsGKRKLItsEEERsPAKRGRKSAtVKPGAVGAGE
Q12965	S1002	Sugiyama	MYO1E MYO1C	RSNQKSLyTsMARPPLPRQQstssDRVsQtPEsLDFLKVPD
Q13043	T340	EPSD\|PSP	STK4 KRS2 MST1	sEEDEMDsGtMVRAVGDEMGtVRVASTMTDGANtMIEHDDT
Q13242	S172	Sugiyama	SRSF9 SFRS9 SRP30C	yLRKEDMEYALRKLDDTKFRsHEGEtsYIRVYPERstsYGY
Q13243	S153	Sugiyama	SRSF5 HRS SFRS5 SRP40	EVTFADAHRPKLNEGVVEFAsYGDLKNAIEKLSGKEINGRK
Q13257	S185	EPSD\|PSP	MAD2L1 MAD2	EKWEEsGPQFITNsEEVRLRsFtTTIHKVNsMVAYKIPVND
Q13257	T187	EPSD\|PSP	MAD2L1 MAD2	WEEsGPQFITNsEEVRLRsFtTTIHKVNsMVAYKIPVND__
Q13263	S473	EPSD\|PSP\|Sugiyama	TRIM28 KAP1 RNF96 TIF1B	sGDDPyssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLERL
Q13283	S362	Sugiyama	G3BP1 G3BP	LFIGNLPHEVDKSELKDFFQsyGNVVELRINsGGKLPNFGF
Q13283	S67	Sugiyama	G3BP1 G3BP	sNGKPADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLN
Q13310	T191	Sugiyama	PABPC4 APP1 PABP4	GRFKSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELF
Q13310	Y194	Sugiyama	PABPC4 APP1 PABP4	KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF
Q13439	S71	EPSD\|PSP	GOLGA4	PNRESGDTQSFAQKLQLRVPsVEsLFRsPIKESLFRsssKE
Q13442	S19	Sugiyama	PDAP1 HASPP28	__MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE
Q13442	T18	Sugiyama	PDAP1 HASPP28	___MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEE
Q13470	S502	EPSD\|PSP	TNK1	PPARGQRRNMPLERMKGIsRsLEsVLsLGPRPtGGGssPPE
Q13509	S115	Sugiyama	TUBB3 TUBB4	SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509	T107	Sugiyama	TUBB3 TUBB4	PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13885	S115	Sugiyama	TUBB2A TUBB2	sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885	T107	Sugiyama	TUBB2A TUBB2	PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q13907	S55	EPSD\|PSP	IDI1	TKKNCHLNENIEKGLLHRAFsVFLFNTENKLLLQQRSDAKI
Q14004	S437	EPSD\|PSP	CDK13 CDC2L CDC2L5 CHED KIAA1791	SRHSRSRSRHRLSRSRSRHssIsPsTLTLKSSLAAELNKNK
Q14152	S1256	Sugiyama	EIF3A EIF3S10 KIAA0139	EDRFRRPRDEGGWRRGPAEEsssWRDssRRDDRDRDDRRRE
Q14152	S584	Sugiyama	EIF3A EIF3S10 KIAA0139	EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14186	S23	EPSD\|PSP	TFDP1 DP1	KDAGLIEANGELKVFIDQNLsPGKGVVsLVAVHPSTVNPLG
Q14247	S298	EPSD\|PSP	CTTN EMS1	ERQDsAAVGFDyKEKLAKHEsQQDySKGFGGKyGVQKDRMD
Q14498	S334	Sugiyama	RBM39 HCC1 RNPC2	FELAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtT
Q14498	S337	Sugiyama	RBM39 HCC1 RNPC2	AGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGRL
Q14498	T330	Sugiyama	RBM39 HCC1 RNPC2	QLNGFELAGRPMKVGHVTERtDAssAssFLDsDELERtGID
Q14568	S53	Sugiyama	HSP90AA2P HSP90AA2 HSPC2 HSPCAL3	IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14568	Y283	Sugiyama	HSP90AA2P HSP90AA2 HSPC2 HSPCAL3	sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI
Q14669	S1078	EPSD\|PSP	TRIP12 KIAA0045 ULF	NSNNIEPARTAGGSGLARAAsKDTISNNREKIKGWIKEQAH
Q14676	T523	EPSD\|PSP	MDC1 KIAA0170 NFBD1	KssPGIHLERsQAsttVDINtQVEKEVPPGSAIIHIKKHQV
Q14738	S60	EPSD\|PSP	PPP2R5D	PQPQPQPQAQSQPPSSNKRPsNstPPPTQLSKIKYsGGPQI
Q14966	S375	EPSD\|PSP	ZNF638 NP220 ZFML	PVINSSNVHVGsRGsKKNYQsQADIPIRsPFGIVKASWLPK
Q15084	S389	Sugiyama	PDIA6 ERP5 P5 TXNDC7	FALLKGsFsEQGINEFLRELsFGRGstAPVGGGAFPtIVER
Q15181	S248	Sugiyama	PPA1 IOPPP PP	KALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDALPP
Q15181	T245	Sugiyama	PPA1 IOPPP PP	DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA
Q15185	S72	Sugiyama	PTGES3 P23 TEBP	EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE
Q15185	S82	Sugiyama	PTGES3 P23 TEBP	NDsKHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVD
Q15642	S296	Sugiyama	TRIP10 CIP4 STOT STP	FARPGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRS
Q15648	T704	EPSD\|PSP	MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2	sNKTKKKKSSRLPPEKPKHQtEDDFQRELFSMDVDSQNPIF
Q16143	Y127	SIGNOR\|EPSD\|PSP	SNCB	LIEPLMEPEGEsYEDPPQEEyQEYEPEA_____________
Q16181	T228	EPSD\|PSP	SEPTIN7 CDC10 SEPT7	KKQIMKEIQEHKIKIyEFPEtDDEEENKLVKKIKDRLPLAV
Q16204	S240	EPSD\|PSP	CCDC6 D10S170 TST1	RMDKLEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMR
Q16204	S244	EPSD\|PSP	CCDC6 D10S170 TST1	LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF
Q16576	S145	Sugiyama	RBBP7 RBAP46	EVNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGE
Q16695	T46	Sugiyama	H3-4 H3FT HIST3H3	ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q27J81	S574	EPSD\|PSP	INF2 C14orf151 C14orf173	HRRVNPPtLRMKKLNWQKLPsNVAREHNsMWAsLssPDAEA
Q32P44	S176	EPSD\|PSP	EML3	sSssssPSERPRQKLSRKAIssANLLVRsGstESRGGKDPL
Q32P51	S22	Sugiyama	HNRNPA1L2 HNRNPA1L	SKSASPKEPEQLRKLFIGGLsFEtTDESLRSHFEQWGTLTD
Q32P51	T25	Sugiyama	HNRNPA1L2 HNRNPA1L	ASPKEPEQLRKLFIGGLsFEtTDESLRSHFEQWGTLTDCVV
Q53F19	S100	EPSD\|PSP	NCBP3 C17orf85	VTSKEAIEKKEQRAKRFHFRsEVNLAQRNVALDRDMMKKAI
Q53H47	S508	SIGNOR\|EPSD\|PSP	SETMAR	FLDRIVTCDEKWILYDNRRRsAQWLDQEEAPKHFPKPILHP
Q58FF8	Y198	Sugiyama	HSP90AB2P HSP90BB	DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI
Q5JSZ5	S166	EPSD\|PSP	PRRC2B BAT2L BAT2L1 KIAA0515	QLNGKPVGHEGGLRGSSRLLsFsPEEFPTLKAAGGQDKAGK
Q5JTH9	S1049	EPSD\|PSP	RRP12 KIAA0690	HRVLVNIRKAEARAKRHRALsQAAVEEEEEEEEEEEPAQGK
Q5QNW6	S39	Sugiyama	H2BC18 HIST2H2BF	VTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q5T5Y3	S1398	Sugiyama	CAMSAP1	sCSDsGTKCSSTPDNLSRtQsGssLsLAsAAttEPESVHSG
Q5T8P6	T839	EPSD\|PSP	RBM26 C13orf10 PRO1777	LDLyKKMQAGEEVTELRRKYtELQLEAAKRGILSSGRGRGI
Q5UIP0	S2205	EPSD\|PSP	RIF1	GLKRsQEDEIssPVNKVRRVsFADPIYQAGLADDIDRRCSI
Q5VTE0	T23	Sugiyama	EEF1A1P5 EEF1AL3	KEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFE
Q6NXT2	T45	Sugiyama	H3-5 H3F3C	AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6PD62	S1081	EPSD\|PSP	CTR9 KIAA0155 SH2BP1	ENQNKSGsEAGsPRRPRRQRsDQDsDsDQPSRKRRPsGsEQ
Q6PEY2	S48	Sugiyama	TUBA3E	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2	S54	Sugiyama	TUBA3E	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q6PKG0	T747	Sugiyama	LARP1 KIAA0731 LARP	PPVDPNQEVPPGPPRFQQVPtDALANKLFGAPEPstIARsL
Q6S8J3	S1068	Sugiyama	POTEE A26C1A POTE2	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6T4R5	T401	EPSD\|PSP	NHS	CSLVHSQsVLQRRRKLRRRKtISGIPRRVQQEIDsDEsPVA
Q6UB98	S76	EPSD	ANKRD12 ANCO2 KIAA0874	SSMKRKLPFTISPSRNEERDsDTDSDPGHTSENWGERLISS
Q6ZMR3	S161	Sugiyama	LDHAL6A LDHL2	DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3	S167	Sugiyama	LDHAL6A LDHL2	AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71DI3	T46	Sugiyama	H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D	ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71U36	S48	Sugiyama	TUBA1A TUBA3	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36	S54	Sugiyama	TUBA1A TUBA3	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q71U36	T73	Sugiyama	TUBA1A TUBA3	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36	T80	Sugiyama	TUBA1A TUBA3	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36	T82	Sugiyama	TUBA1A TUBA3	VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71U36	Y83	Sugiyama	TUBA1A TUBA3	PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q7KZF4	S150	Sugiyama	SND1 TDRD11	EGLAtRREGMRANNPEQNRLsECEEQAKAAKKGMWSEGNGS
Q7Z2Z1	S1045	EPSD\|PSP	TICRR C15orf42	HsASFYSVSQPKSRSVQRVHsFQQDKSDQRENsPVQsIRsP
Q7Z2Z1	S1115	PSP	TICRR C15orf42	LDSEVPAAyQtPKKSHQKSLsFSKTTPRRIsHtPQtPLYtP
Q7Z2Z1	S1894	EPSD\|PSP	TICRR C15orf42	LPstVEDsPFSRAFSRRRPIsRTYtRKKLMGTWLEDL____
Q7Z2Z1	S865	EPSD\|PSP	TICRR C15orf42	QELRTRSAKKRRKNALIRHKsIAEVSQNLRQIEIPKVSKRA
Q7Z2Z1	T1898	EPSD\|PSP	TICRR C15orf42	VEDsPFSRAFSRRRPIsRTYtRKKLMGTWLEDL________
Q7Z417	S652	Sugiyama	NUFIP2 KIAA1321 PIG1	NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI
Q7Z4V5	S300	Sugiyama	HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604	AEKPLPKPRGRKPKPERPPSssSSDSDSDEVDRISEWKRRD
Q7Z4V5	S395	Sugiyama	HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604	REDDEPVKKRGRKGRGRGPPsssDsEPEAELEREAKKSAKK
Q7Z4V5	S454	Sugiyama	HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604	VRPEEKQQAKPVKVERTRKRsEGFsMDRKVEKKKEPSVEEK
Q86UE8	S686	EPSD\|PSP	TLK2	SVGVIFYQCLYGRKPFGHNQsQQDILQENtILKATEVQFPP
Q86UE8	S750	SIGNOR	TLK2	IDVQQLACDPYLLPHIRKsVstssPAGAAIAstsGAsNNss
Q86WB0	T84	EPSD\|PSP	ZC3HC1 NIPA HSPC216	QAEQPSLESTSKEAFFSRVEtFSsLKWAGKPFELSPLVCAK
Q86WR7	S43	EPSD\|PSP	PROSER2 C10orf47	LRAFsRGGsLESRSSSSRsRsFtLDDEsLKYLTHEEKDVLL
Q8N201	S495	Sugiyama	INTS1 KIAA1440 UNQ1821/PRO3434	KFLAMVFQDLLTNKDDYLRAsRALLREIIKQTKHEINFQAF
Q8N4C8	T280	EPSD\|PSP	MINK1 B55 MAP4K6 MINK YSK2 ZC3	KKFIDFIDTCLIKTYLSRPPtEQLLKFPFIRDQPTERQVRI
Q8N8S7	S125	Sugiyama	ENAH MENA	MHALEVLNSQETGPTLPRQNsQLPAQVQNGPSQEELEIQRR
Q8NBJ7	S281	Sugiyama	SUMF2 PSEC0171 UNQ1968/PRO4500	ADGsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPPGEL
Q8NBJ7	S283	Sugiyama	SUMF2 PSEC0171 UNQ1968/PRO4500	GsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPPGEL__
Q8NBS9	S426	Sugiyama	TXNDC5 TLP46 UNQ364/PRO700	KKVSEHSGGRDLDSLHRFVLsQAKDEL______________
Q8NG66	S273	SIGNOR\|EPSD\|PSP	NEK11	PERYPKELNAIMESMLNKNPsLRPSAIEILKIPYLDEQLQN
Q8NHW5	S307	Sugiyama	RPLP0P6	AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
Q8TAM6	S280	Sugiyama	ERMN KIAA1189	TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8TD47	T141	Sugiyama	RPS4Y2 RPS4Y2P	YKLCKVRKITVGTKGIPHLVtHDARTIRYPDPLIKVNDTVQ
Q8WWI1	S1510	EPSD\|PSP	LMO7 FBX20 FBXO20 KIAA0858	RsAsVNKEPVSLPGIMRRGEsLDNLDsPRSNSWRQPPWLNQ
Q8WX93	S479	Sugiyama	PALLD KIAA0992 CGI-151	VLECRVRGAPPLQVQWFRQGsEIQDsPDFRILQKKPRSTAE
Q92974	S172	EPSD\|PSP	ARHGEF2 KIAA0651 LFP40	ttNIAGHFNDEsPLGLRRILsQstDsLNMRNRTLsVESLID
Q93079	S39	Sugiyama	H2BC9 H2BFJ HIST1H2BH	VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q96E09	S37	SIGNOR\|PSP	PABIR1 C9orf42 FAM122A	GGsPAEGGGSGGGGGLRRsNsAPLIHGLsDtsPVFQAEAPS
Q96GD4	S331	SIGNOR\|EPSD\|PSP	AURKB AIK2 AIM1 AIRK2 ARK2 STK1 STK12 STK5	NPSERLPLAQVSAHPWVRANsRRVLPPSALQSVA_______
Q96PK6	S618	EPSD\|PSP	RBM14 SIP	MSKRYGSDRRLAELsDYRRLsEsQLsFRRsPtKSSLDYRRL
Q96PK6	S627	EPSD\|PSP	RBM14 SIP	RLAELsDYRRLsEsQLsFRRsPtKSSLDYRRLPDAHsDyAR
Q96PK6	T629	EPSD\|PSP	RBM14 SIP	AELsDYRRLsEsQLsFRRsPtKSSLDYRRLPDAHsDyARYs
Q96QD9	T205	EPSD\|PSP	FYTTD1 UIF	DTRQATFLFRRGLKVQAQLNtEQLLDDVVAKRTRQWRTSTT
Q96RL1	S627	EPSD\|PSP	UIMC1 RAP80 RXRIP110	KWQQRLKNPKEKGHSEGRLLsFLEQSEHKTSDADIKSSETG
Q96ST3	T434	EPSD\|PSP	SIN3A	NNKPQRPsQNGCQIRRHPTGttPPVKKKPKLLNLKDsSMAD
Q96T58	T1059	EPSD\|PSP	SPEN KIAA0929 MINT SHARP	PVRKEILKRESKKIKLDRLNtVAsPKDCQELASISVGsGSR
Q99590	S1127	EPSD\|PSP	SCAF11 CASP11 SFRS2IP SIP1 SRSF2IP	sNssGsEsFKFVEQQSYKRKsEQEFSFDtPADRSGWTSASS
Q99613	S638	Sugiyama	EIF3C EIF3S8	ICAFRQGLTKDAHNALLDIQssGRAKELLGQGLLLRSLQER
Q99613	S865	Sugiyama	EIF3C EIF3S8	HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99848	T182	EPSD\|PSP	EBNA1BP2 EBP2	ERSEKAKQLRALRKYGKKVQtEVLQKRQQEKAHMMNAIKKY
Q99877	S39	Sugiyama	H2BC15 H2BFD HIST1H2BN	VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q99879	S39	Sugiyama	H2BC14 H2BFE HIST1H2BM	INKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q99880	S39	Sugiyama	H2BC13 H2BFC HIST1H2BL	VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q9BQE3	S48	Sugiyama	TUBA1C TUBA6	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3	S54	Sugiyama	TUBA1C TUBA6	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q9BQE3	T73	Sugiyama	TUBA1C TUBA6	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3	T80	Sugiyama	TUBA1C TUBA6	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3	T82	Sugiyama	TUBA1C TUBA6	VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BQE3	Y83	Sugiyama	TUBA1C TUBA6	PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BQG0	S1310	EPSD\|PSP	MYBBP1A P160	sPLsALARKKARLsLVIRSPsLLQSGAKKKAQVRKAGKP__
Q9BRD0	S18	EPSD\|PSP	BUD13	___MAAAPPLSKAEYLKRYLsGADAGVDRGsESGRKRRKKR
Q9BTD8	S406	EPSD\|PSP	RBM42	GDLGNEVNDDILARAFSRFPsFLKAKVIRDKRTGKTKGyGF
Q9BVA1	S115	Sugiyama	TUBB2B	sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1	T107	Sugiyama	TUBB2B	PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BW19	S26	EPSD\|PSP	KIFC1 HSET KNSL2	sPLLEVKGNIELKRPLIKAPsQLPLsGsRLKRRPDQMEDGL
Q9BXB4	S189	EPSD\|PSP	OSBPL11 ORP11 OSBP12	KsRsFsLAsssNsPIsQRRPsQNAIsFFNVGHSKLQSLSKR
Q9BXW9	S331	SIGNOR\|EPSD\|PSP	FANCD2 FACD	VLPSRLQAsQVKLKSKGRAsssGNQEssGQSCIILLFDVIK
Q9BY77	S63	EPSD\|PSP	POLDIP3 KIAA1649 PDIP46	QstRTATFQQRFDARQKIGLsDARLKLGVKDAREKLLQKDA
Q9BYX7	S368	Sugiyama	POTEKP ACTBL3 FKSG30	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BZI7	T169	Sugiyama	UPF3B RENT3B UPF3X	TKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIEAKN
Q9GZR7	S82	EPSD\|PSP	DDX24	AKNPSsLFsKEAPKRKAQAVsEEEEEEEGKsssPKKKIKLK
Q9H0H5	S203	EPSD\|PSP	RACGAP1 KIAA1478 MGCRACGAP	RRstsRQFVDGPPGPVKKtRsIGsAVDQGNEsIVAKTTVTV
Q9H788	S315	Sugiyama	SH2D4A PPP1R38 SH2A	LNSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRA
Q9H788	Y131	Sugiyama	SH2D4A PPP1R38 SH2A	EEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKDIWKKVAE
Q9H8G2	S203	EPSD\|PSP	CAAP1 C9orf82 CAAP	LELLSEKKILKILEGDNGMDsDMEEEADDGSKMGSDLVSQQ
Q9H8N7	S447	EPSD\|PSP	ZNF395 HDBP2 PBF	SVSWAAAPSAACSLSPVRSRsLsFsEPQQPAPAMKSHLIVt
Q9HAW4	T916	SIGNOR\|iPTMNet\|EPSD\|PSP	CLSPN	LASMDENAMDANMDELLDLCtGKFTSQAEKHLPRKSDKKEN
Q9HB96	S374	SIGNOR\|EPSD\|PSP	FANCE FACE	DLSLSNATVLTRSLFLGRILsLTSSASRLLTTALTSFCAKY
Q9HB96	T346	SIGNOR\|EPSD\|PSP	FANCE FACE	LLCAQLQLPQLSDLGLLRLCtWLLALSPDLSLSNATVLTRS
Q9HC62	S344	EPSD\|PSP	SENP2 KIAA1331	EVSARLRLGsGSNGLLRRKVsIIETKEKNCSGKERDRRTDD
Q9NP61	S366	Sugiyama	ARFGAP3 ARFGAP1	DDsyFTSSSSYFDEPVELRsssFssWDDssDSyWKKETSKD
Q9NQ39	S157	Sugiyama	RPS10P5 RPS10L	TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NRL2	S1320	EPSD\|PSP	BAZ1A ACF1 WCRF180 HSPC317	QstPKTTVSSKTGRSLRKINsAPPtETKSLRIASRSTRHsH
Q9NRM7	S408	EPSD\|PSP	LATS2 KPM	APPRAHVAFRPDCPVPSRTNsFNSHQPRPGPPGKAEPSLPA
Q9NRM7	S835	EPSD\|PSP	LATS2 KPM	GFRWTHNSKYYQKGsHVRQDsMEPsDLWDDVsNCRCGDRLK
Q9NS23	S188	SIGNOR	RASSF1 RDA32	IKVQLKLVRPVsVPSSKKPPsLQDARRGPGRGTSVRRRtsF
Q9NS23	T38	PSP	RASSF1 RDA32	RAGKGRTRLERANALRIARGtACNPtRQLVPGRGHRFQPAG
Q9NS23	T43	PSP	RASSF1 RDA32	RTRLERANALRIARGtACNPtRQLVPGRGHRFQPAGPATHT
Q9NUU7	S92	EPSD\|PSP	DDX19A DDX19L	NtNQVEVLQRDPNsPLysVKsFEELRLKPQLLQGVYAMGFN
Q9NVU7	T552	Sugiyama	SDAD1 NUC130	SMPMEERKAKAAAISTSRVLtQEDFQKIRMAQMRKELDAAP
Q9NW13	S122	PSP	RBM28	PKAKKAKVADKKARLIIRNLsFKCSEDDLKTVFAQFGAVLE
Q9NWH9	S748	EPSD\|PSP	SLTM MET	RPRDVDHRRDDPYWsENKKLsLDTDARFGHGSDYSRQQNRF
Q9NWH9	S815	EPSD\|PSP	SLTM MET	RFVGQsEGKKARPTARREDPsFERYPKNFSDSRRNEPPPPR
Q9NXE8	S337	EPSD\|PSP	CWC25 CCDC49	PSPKKEVYQRRHAPGYTRKLsAEELERKRQEMMENAKWREE
Q9NYB9	S22	Sugiyama	ABI2 ARGBPIA	AELQMLLEEEIPGGRRALFDsytNLERVADyCENNyIQSAD
Q9P2D1	T1227	EPSD\|PSP	CHD7 KIAA1416	EVELTNIQKKYYRAILEKNFtFLSKGGGQANVPNLLNTMME
Q9UEY8	S693	EPSD\|PSP	ADD3 ADDL	sPEGsPsKsPsKKKKKFRTPsFLKKNKKKEKVEA_______
Q9UGV2	S331	Sugiyama	NDRG3	QGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQ
Q9UGV2	T329	Sugiyama	NDRG3	FLQGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVts
Q9UGY1	S21	Sugiyama	NOL12	MGRNKKKKRDGDDRRPRLVLsFDEEKRREyLTGFHKRKVER
Q9UI15	S185	Sugiyama	TAGLN3 NP25	EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______
Q9UI15	T190	Sugiyama	TAGLN3 NP25	GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UII2	S63	Sugiyama	ATP5IF1 ATPI ATPIF1	AGGAFGKREQAEEERyFRAQsREQLAALKKHHEEEIVHHKK
Q9UJM3	S251	SIGNOR\|EPSD\|PSP	ERRFI1 MIG6	GVPDPNPPPPQTHRRLRRsHsGPAGsFNKPAIRIsNCCIHR
Q9UJM3	S302	EPSD\|PSP	ERRFI1 MIG6	EVPPRVPIPPRPVKPDYRRWsAEVTSSTYSDEDRPPKVPPR
Q9UKI8	S679	EPSD\|PSP	TLK1 KIAA0137	SVGVIFFQCLYGRKPFGHNQsQQDILQENtILKATEVQFPV
Q9UKI8	S743	SIGNOR\|ELM\|EPSD\|PSP	TLK1 KIAA0137	FDVHQLANDPYLLPHMRRsNssGNLHMAGLtAsPTPPssSI
Q9UKM9	T160	EPSD\|PSP	RALY HNRPCL2 P542	PRAVPVKRPRVTVPLVRRVKtNVPVKLFARSTAVTTssAKI
Q9UMR2	S93	EPSD\|PSP	DDX19B DBP5 DDX19 TDBP	NtNQVEVLQRDPNsPLysVKsFEELRLKPQLLQGVYAMGFN
Q9UNX3	T8	Sugiyama	RPL26L1 RPL26P1	_____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UNZ2	S192	Sugiyama	NSFL1C UBXN2C	KRQHssQDVHVVLKLWKsGFsLDNGELRSyQDPsNAQFLEs
Q9UPP1	S904	EPSD\|PSP	PHF8 KIAA1111 ZNF422	RVTPTLPKQDRPVREGTRVAsIETGLAAAAAKLAQQELQKA
Q9UQ35	S1455	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	PsRRsRsGssPGLRDGsGtPsRHsLsGssPGMKDIPRtPSR
Q9UQ35	S1497	EPSD\|PSP	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	RsECDssPEPKALPQtPRPRsRsPssPELNNKCLtPQRERs
Q9UQ35	S1499	EPSD\|PSP	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	ECDssPEPKALPQtPRPRsRsPssPELNNKCLtPQRERsGs
Q9UQ35	S1539	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	sEssVDQKtVARtPLGQRsRsGssQELDVKPsAsPQERsEs
Q9UQ35	S1541	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	ssVDQKtVARtPLGQRsRsGssQELDVKPsAsPQERsEsDs
Q9UQ35	S2280	EPSD\|PSP	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	RtPAAAAAMNLAsPRtAVAPsAVNLADPRtPtAPAVNLAGA
Q9UQ35	S2388	EPSD\|PSP	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	sARMAPALsGANLtsPRVPLsAyERVsGRtsPPLLDRARsR
Q9UQ35	T2252	EPSD\|PSP	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	IPAAsAAAMNLAsARtPAIPtAVNLADsRtPAAAAAMNLAs
Q9UQ80	S267	Sugiyama	PA2G4 EBP1	YKRDPSKQYGLKMKtSRAFFsEVERRFDAMPFtLRAFEDEK
Q9UQ84	S746	PSP	EXO1 EXOI HEX1	HFSKKDTPLRNKVPGLYKSSsADSLSTTKIKPLGPARASGL
Q9Y294	S166	SIGNOR\|PSP	ASF1A CGI-98 HSPC146	VTRFHINWEDNtEKLEDAEssNPNLQsLLstDALPsAsKGW
Q9Y2B0	S63	Sugiyama	CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426	AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE
Q9Y2T7	S137	Sugiyama	YBX2 CSDA3 MSY2	EDVFVHQtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEA
Q9Y2T7	T115	EPSD\|PSP\|Sugiyama	YBX2 CSDA3 MSY2	LGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIKRNNPRKFL
Q9Y2T7	T143	Sugiyama	YBX2 CSDA3 MSY2	QtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEATNVTGP
Q9Y3U8	S91	Sugiyama	RPL36	KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y3Y2	T212	EPSD\|PSP	CHTOP C1orf77 FOP HT031 PP7704	FGGRGRGRGRGRGALARPVLtKEQLDNQLDAYMSKTKGHLD
Q9Y4F5	S655	EPSD\|PSP	CEP170B FAM68C KIAA0284	ASRPLGAAPQAEHQGLPVPGsPGGQKWVSRWASLADsYsDP
Q9Y520	S661	EPSD\|PSP	PRRC2C BAT2D1 BAT2L2 KIAA1096 XTP2	tPVVHEtEPEsGsQPRPAVLsGYFKQFQKSLPPRFQRQQEQ
Q9Y570	S15	EPSD\|PSP	PPME1 PME1 PP2593 PRO0750	______MSALEKSMHLGRLPsRPPLPGsGGsQsGAKMRMGP
Q9Y5S9	S56	Sugiyama	RBM8A RBM8 HSPC114 MDS014	KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y696	T222	Sugiyama	CLIC4	AKKYRNFDIPKEMTGIWRYLtNAysRDEFtNtCPsDKEVEI
Q9Y696	Y225	Sugiyama	CLIC4	YRNFDIPKEMTGIWRYLtNAysRDEFtNtCPsDKEVEIAys

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download

name	reactome_id	p	-log10p	ref_path	ref_path_lowest
Cellular response to heat stress	R-HSA-3371556	1.712630e-12	11.766	0	0
HSF1-dependent transactivation	R-HSA-3371571	1.032909e-10	9.986	0	0
Regulation of HSF1-mediated heat shock response	R-HSA-3371453	6.454097e-10	9.190	0	0
Cell Cycle	R-HSA-1640170	2.847793e-09	8.545	1	0
Attenuation phase	R-HSA-3371568	5.040232e-09	8.298	0	0
Diseases of signal transduction by growth factor receptors and second messengers	R-HSA-5663202	1.576863e-08	7.802	0	0
Cell Cycle Checkpoints	R-HSA-69620	2.773509e-08	7.557	1	0
HSF1 activation	R-HSA-3371511	4.497597e-08	7.347	0	0
Cell Cycle, Mitotic	R-HSA-69278	1.027074e-07	6.988	0	0
Signal Transduction	R-HSA-162582	2.497894e-07	6.602	1	0
Amplification of signal from the kinetochores	R-HSA-141424	4.948543e-07	6.306	0	0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	R-HSA-141444	4.948543e-07	6.306	0	0
Regulation of TP53 Activity	R-HSA-5633007	2.578614e-06	5.589	1	0
Mitotic Spindle Checkpoint	R-HSA-69618	4.320894e-06	5.364	0	0
Mitotic Prometaphase	R-HSA-68877	4.671614e-06	5.331	0	0
Chromatin modifying enzymes	R-HSA-3247509	6.145750e-06	5.211	0	0
M Phase	R-HSA-68886	6.338121e-06	5.198	0	0
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	9.033809e-06	5.044	0	0
Axon guidance	R-HSA-422475	1.208833e-05	4.918	0	0
Chromatin organization	R-HSA-4839726	1.297097e-05	4.887	0	0
Death Receptor Signaling	R-HSA-73887	2.947909e-05	4.530	0	0
Cell death signalling via NRAGE, NRIF and NADE	R-HSA-204998	3.138379e-05	4.503	0	0
Signaling by ALK fusions and activated point mutants	R-HSA-9725370	4.448817e-05	4.352	0	0
Signaling by ALK in cancer	R-HSA-9700206	4.448817e-05	4.352	0	0
Regulation of TP53 Activity through Phosphorylation	R-HSA-6804756	4.953420e-05	4.305	1	1
Mitotic Anaphase	R-HSA-68882	6.192615e-05	4.208	0	0
EML4 and NUDC in mitotic spindle formation	R-HSA-9648025	6.309471e-05	4.200	0	0
Separation of Sister Chromatids	R-HSA-2467813	6.543422e-05	4.184	0	0
Nervous system development	R-HSA-9675108	6.647991e-05	4.177	0	0
Mitotic Metaphase and Anaphase	R-HSA-2555396	6.975468e-05	4.156	0	0
Apoptotic cleavage of cellular proteins	R-HSA-111465	1.125268e-04	3.949	0	0
NRAGE signals death through JNK	R-HSA-193648	1.276723e-04	3.894	0	0
Cellular responses to stimuli	R-HSA-8953897	1.415623e-04	3.849	0	0
Regulation of MECP2 expression and activity	R-HSA-9022692	1.539508e-04	3.813	0	0
Oncogenic MAPK signaling	R-HSA-6802957	1.620038e-04	3.790	0	0
p75 NTR receptor-mediated signalling	R-HSA-193704	1.714248e-04	3.766	0	0
G alpha (12/13) signalling events	R-HSA-416482	2.029917e-04	3.693	0	0
TP53 Regulates Transcription of DNA Repair Genes	R-HSA-6796648	2.029917e-04	3.693	1	1
VEGFA-VEGFR2 Pathway	R-HSA-4420097	2.299790e-04	3.638	0	0
Membrane Trafficking	R-HSA-199991	2.550542e-04	3.593	0	0
Oxidative Stress Induced Senescence	R-HSA-2559580	2.812429e-04	3.551	0	0
Downregulation of SMAD2/3:SMAD4 transcriptional activity	R-HSA-2173795	3.283674e-04	3.484	0	0
Regulation of TP53 Expression and Degradation	R-HSA-6806003	4.013287e-04	3.396	0	0
Specification of primordial germ cells	R-HSA-9827857	4.424658e-04	3.354	0	0
Apoptotic execution phase	R-HSA-75153	4.468899e-04	3.350	0	0
Semaphorin interactions	R-HSA-373755	5.739594e-04	3.241	0	0
Chaperone Mediated Autophagy	R-HSA-9613829	6.492930e-04	3.188	0	0
Programmed Cell Death	R-HSA-5357801	6.997596e-04	3.155	0	0
FOXO-mediated transcription of cell cycle genes	R-HSA-9617828	8.197766e-04	3.086	0	0
Signaling by RAF1 mutants	R-HSA-9656223	8.401295e-04	3.076	0	0
Transcriptional Regulation by TP53	R-HSA-3700989	8.410518e-04	3.075	1	0
Negative regulation of MAPK pathway	R-HSA-5675221	8.401295e-04	3.076	0	0
Cellular Senescence	R-HSA-2559583	9.080929e-04	3.042	0	0
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-5693616	9.759564e-04	3.011	1	1
Impaired BRCA2 binding to RAD51	R-HSA-9709570	1.087703e-03	2.963	0	0
Signaling by RAS mutants	R-HSA-6802949	1.075255e-03	2.968	0	0
Paradoxical activation of RAF signaling by kinase inactive BRAF	R-HSA-6802955	1.075255e-03	2.968	0	0
Signaling downstream of RAS mutants	R-HSA-9649948	1.075255e-03	2.968	0	0
Signaling by moderate kinase activity BRAF mutants	R-HSA-6802946	1.075255e-03	2.968	0	0
Regulation of TNFR1 signaling	R-HSA-5357905	1.075255e-03	2.968	0	0
Signaling by VEGF	R-HSA-194138	1.067236e-03	2.972	0	0
ISG15 antiviral mechanism	R-HSA-1169408	1.125005e-03	2.949	0	0
Regulation of necroptotic cell death	R-HSA-5675482	1.181399e-03	2.928	0	0
HDR through Single Strand Annealing (SSA)	R-HSA-5685938	1.181399e-03	2.928	0	0
MECP2 regulates neuronal receptors and channels	R-HSA-9022699	1.296971e-03	2.887	0	0
Transport of Mature mRNAs Derived from Intronless Transcripts	R-HSA-159234	1.295544e-03	2.888	0	0
EPH-Ephrin signaling	R-HSA-2682334	1.470050e-03	2.833	0	0
Signaling by Hippo	R-HSA-2028269	1.491584e-03	2.826	0	0
Apoptosis	R-HSA-109581	1.495203e-03	2.825	0	0
Transport of the SLBP Dependant Mature mRNA	R-HSA-159230	1.521539e-03	2.818	0	0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	R-HSA-2173793	1.586701e-03	2.800	0	0
MAPK family signaling cascades	R-HSA-5683057	1.527346e-03	2.816	0	0
Constitutive Signaling by AKT1 E17K in Cancer	R-HSA-5674400	1.536809e-03	2.813	0	0
RUNX3 regulates WNT signaling	R-HSA-8951430	1.703960e-03	2.769	0	0
TNFR1-induced NF-kappa-B signaling pathway	R-HSA-5357956	1.716067e-03	2.765	0	0
Regulation of PTEN localization	R-HSA-8948747	1.703960e-03	2.769	0	0
Signaling by BRAF and RAF1 fusions	R-HSA-6802952	1.787536e-03	2.748	0	0
Diseases of DNA Double-Strand Break Repair	R-HSA-9675136	1.940417e-03	2.712	0	0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function	R-HSA-9701190	1.940417e-03	2.712	0	0
Cellular responses to stress	R-HSA-2262752	1.990236e-03	2.701	0	0
Homologous DNA Pairing and Strand Exchange	R-HSA-5693579	1.995593e-03	2.700	1	0
Transcriptional regulation by RUNX1	R-HSA-8878171	2.069028e-03	2.684	0	0
G2/M Checkpoints	R-HSA-69481	2.397038e-03	2.620	1	0
Transport of Mature mRNA Derived from an Intronless Transcript	R-HSA-159231	2.490167e-03	2.604	0	0
HDR through Homologous Recombination (HRR)	R-HSA-5685942	2.509248e-03	2.600	1	0
RUNX3 regulates CDKN1A transcription	R-HSA-8941855	2.559187e-03	2.592	0	0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	R-HSA-9828211	2.881064e-03	2.540	0	0
Impaired BRCA2 binding to PALB2	R-HSA-9709603	2.888766e-03	2.539	0	0
Late endosomal microautophagy	R-HSA-9615710	2.894393e-03	2.538	0	0
Transport of the SLBP independent Mature mRNA	R-HSA-159227	3.010569e-03	2.521	0	0
Regulation of TP53 Degradation	R-HSA-6804757	3.069889e-03	2.513	0	0
Processing of DNA double-strand break ends	R-HSA-5693607	2.912044e-03	2.536	1	1
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	R-HSA-8849469	2.881064e-03	2.540	0	0
Calmodulin induced events	R-HSA-111933	3.069889e-03	2.513	0	0
CaM pathway	R-HSA-111997	3.069889e-03	2.513	0	0
Intracellular signaling by second messengers	R-HSA-9006925	3.194702e-03	2.496	0	0
Mitotic G2-G2/M phases	R-HSA-453274	3.267983e-03	2.486	0	0
Transcriptional regulation by RUNX3	R-HSA-8878159	3.386679e-03	2.470	0	0
Signaling by TGF-beta Receptor Complex	R-HSA-170834	3.386679e-03	2.470	0	0
TNF signaling	R-HSA-75893	3.390404e-03	2.470	0	0
Rab regulation of trafficking	R-HSA-9007101	3.391194e-03	2.470	0	0
TFAP2 (AP-2) family regulates transcription of cell cycle factors	R-HSA-8866911	3.703828e-03	2.431	0	0
EPHB-mediated forward signaling	R-HSA-3928662	3.725613e-03	2.429	0	0
Deactivation of the beta-catenin transactivating complex	R-HSA-3769402	3.811687e-03	2.419	0	0
Sema4D induced cell migration and growth-cone collapse	R-HSA-416572	3.904748e-03	2.408	0	0
Defective homologous recombination repair (HRR) due to PALB2 loss of function	R-HSA-9701193	3.904748e-03	2.408	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	R-HSA-9704331	3.904748e-03	2.408	0	0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	R-HSA-9701192	3.904748e-03	2.408	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	R-HSA-9704646	3.904748e-03	2.408	0	0
Nuclear Envelope Breakdown	R-HSA-2980766	4.027065e-03	2.395	0	0
Mitotic Telophase/Cytokinesis	R-HSA-68884	4.311135e-03	2.365	0	0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	R-HSA-9824878	4.311135e-03	2.365	0	0
NOTCH1 Intracellular Domain Regulates Transcription	R-HSA-2122947	4.365890e-03	2.360	0	0
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	4.474797e-03	2.349	0	0
Response of endothelial cells to shear stress	R-HSA-9860931	4.599744e-03	2.337	0	0
Regulation of TP53 Expression	R-HSA-6804754	4.908740e-03	2.309	0	0
RAF activation	R-HSA-5673000	4.715226e-03	2.326	0	0
Hedgehog 'off' state	R-HSA-5610787	4.960849e-03	2.304	0	0
RIPK1-mediated regulated necrosis	R-HSA-5213460	4.694580e-03	2.328	0	0
Antiviral mechanism by IFN-stimulated genes	R-HSA-1169410	4.707562e-03	2.327	0	0
Signaling by NOTCH1	R-HSA-1980143	5.114297e-03	2.291	0	0
Signaling by Non-Receptor Tyrosine Kinases	R-HSA-9006927	5.298230e-03	2.276	0	0
Signaling by PTK6	R-HSA-8848021	5.298230e-03	2.276	0	0
snRNP Assembly	R-HSA-191859	5.600379e-03	2.252	0	0
Metabolism of non-coding RNA	R-HSA-194441	5.600379e-03	2.252	0	0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	R-HSA-5693567	5.609685e-03	2.251	1	0
Oncogene Induced Senescence	R-HSA-2559585	5.822905e-03	2.235	0	0
Cellular responses to mechanical stimuli	R-HSA-9855142	5.609685e-03	2.251	0	0
Ca-dependent events	R-HSA-111996	5.598442e-03	2.252	0	0
Diseases of DNA repair	R-HSA-9675135	5.420675e-03	2.266	0	0
Regulation of TP53 Activity through Methylation	R-HSA-6804760	6.247497e-03	2.204	0	0
Downregulation of ERBB2:ERBB3 signaling	R-HSA-1358803	6.260937e-03	2.203	0	0
Unblocking of NMDA receptors, glutamate binding and activation	R-HSA-438066	6.781624e-03	2.169	0	0
Signaling by ERBB2	R-HSA-1227986	6.559006e-03	2.183	0	0
Homology Directed Repair	R-HSA-5693538	6.469984e-03	2.189	1	0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	R-HSA-2894862	6.559006e-03	2.183	0	0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	R-HSA-2894858	6.559006e-03	2.183	0	0
Constitutive Signaling by NOTCH1 PEST Domain Mutants	R-HSA-2644606	6.559006e-03	2.183	0	0
Signaling by NOTCH1 PEST Domain Mutants in Cancer	R-HSA-2644602	6.559006e-03	2.183	0	0
G2/M Transition	R-HSA-69275	6.581427e-03	2.182	0	0
Signaling by NOTCH1 in Cancer	R-HSA-2644603	6.559006e-03	2.183	0	0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	R-HSA-9825892	6.781624e-03	2.169	0	0
FLT3 signaling by CBL mutants	R-HSA-9706377	6.992979e-03	2.155	0	0
Cohesin Loading onto Chromatin	R-HSA-2470946	7.396695e-03	2.131	0	0
Regulation of NF-kappa B signaling	R-HSA-9758274	7.466119e-03	2.127	0	0
Aggrephagy	R-HSA-9646399	6.960463e-03	2.157	0	0
Transcriptional Regulation by MECP2	R-HSA-8986944	7.047300e-03	2.152	0	0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	R-HSA-6804116	7.466119e-03	2.127	0	0
Neurexins and neuroligins	R-HSA-6794361	7.324188e-03	2.135	0	0
G2/M DNA damage checkpoint	R-HSA-69473	7.253364e-03	2.139	1	1
Sema4D in semaphorin signaling	R-HSA-400685	7.091896e-03	2.149	0	0
HDMs demethylate histones	R-HSA-3214842	7.091896e-03	2.149	0	0
Muscle contraction	R-HSA-397014	7.793471e-03	2.108	0	0
RMTs methylate histone arginines	R-HSA-3214858	8.057141e-03	2.094	0	0
FLT3 Signaling	R-HSA-9607240	8.384728e-03	2.077	0	0
Notch-HLH transcription pathway	R-HSA-350054	8.735566e-03	2.059	0	0
Downregulation of ERBB2 signaling	R-HSA-8863795	8.983962e-03	2.047	0	0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	R-HSA-5619107	8.983962e-03	2.047	0	0
Striated Muscle Contraction	R-HSA-390522	8.874460e-03	2.052	0	0
Signaling by high-kinase activity BRAF mutants	R-HSA-6802948	8.664759e-03	2.062	0	0
Metalloprotease DUBs	R-HSA-5689901	8.954358e-03	2.048	0	0
MAPK6/MAPK4 signaling	R-HSA-5687128	9.301938e-03	2.031	0	0
DAG and IP3 signaling	R-HSA-1489509	9.576353e-03	2.019	0	0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	R-HSA-933543	1.020699e-02	1.991	0	0
DNA Double-Strand Break Repair	R-HSA-5693532	1.068519e-02	1.971	1	0
Signaling by CSF1 (M-CSF) in myeloid cells	R-HSA-9680350	1.080172e-02	1.967	0	0
IP3 and IP4 transport between cytosol and nucleus	R-HSA-1855196	1.105885e-02	1.956	0	0
IP6 and IP7 transport between cytosol and nucleus	R-HSA-1855229	1.105885e-02	1.956	0	0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	R-HSA-8939246	1.141525e-02	1.943	0	0
ROBO receptors bind AKAP5	R-HSA-9010642	1.141525e-02	1.943	0	0
Downregulation of ERBB4 signaling	R-HSA-1253288	1.141525e-02	1.943	0	0
Regulation of CDH1 Expression and Function	R-HSA-9764265	1.177066e-02	1.929	0	0
Regulation of Expression and Function of Type I Classical Cadherins	R-HSA-9764274	1.177066e-02	1.929	0	0
GLI proteins bind promoters of Hh responsive genes to promote transcription	R-HSA-5635851	1.191756e-02	1.924	0	0
Loss of MECP2 binding ability to the NCoR/SMRT complex	R-HSA-9022537	1.191756e-02	1.924	0	0
Signaling by Ligand-Responsive EGFR Variants in Cancer	R-HSA-5637815	1.376006e-02	1.861	0	0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	R-HSA-1236382	1.376006e-02	1.861	0	0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	R-HSA-450321	1.376006e-02	1.861	0	0
Nuclear Pore Complex (NPC) Disassembly	R-HSA-3301854	1.304137e-02	1.885	0	0
Mitotic Prophase	R-HSA-68875	1.307280e-02	1.884	0	0
Transcriptional Regulation by E2F6	R-HSA-8953750	1.250982e-02	1.903	1	1
Post NMDA receptor activation events	R-HSA-438064	1.337673e-02	1.874	0	0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	R-HSA-8950505	1.356264e-02	1.868	0	0
Regulation of CDH1 Gene Transcription	R-HSA-9764560	1.435734e-02	1.843	0	0
NFE2L2 regulates pentose phosphate pathway genes	R-HSA-9818028	1.438061e-02	1.842	0	0
Signaling by AMER1 mutants	R-HSA-4839748	1.438061e-02	1.842	0	0
Signaling by AXIN mutants	R-HSA-4839735	1.438061e-02	1.842	0	0
Signaling by GSK3beta mutants	R-HSA-5339716	1.438061e-02	1.842	0	0
TICAM1-dependent activation of IRF3/IRF7	R-HSA-9013973	1.438061e-02	1.842	0	0
p75NTR signals via NF-kB	R-HSA-193639	1.615143e-02	1.792	0	0
TICAM1, RIP1-mediated IKK complex recruitment	R-HSA-168927	1.615143e-02	1.792	0	0
IPs transport between nucleus and cytosol	R-HSA-1855170	1.630615e-02	1.788	0	0
Regulation of PD-L1(CD274) transcription	R-HSA-9909649	1.549884e-02	1.810	0	0
Generic Transcription Pathway	R-HSA-212436	1.617957e-02	1.791	1	0
Resolution of D-loop Structures through Holliday Junction Intermediates	R-HSA-5693568	1.630615e-02	1.788	0	0
Selective autophagy	R-HSA-9663891	1.501603e-02	1.823	0	0
Protein-protein interactions at synapses	R-HSA-6794362	1.629857e-02	1.788	0	0
Late Phase of HIV Life Cycle	R-HSA-162599	1.498436e-02	1.824	0	0
Glycolysis	R-HSA-70171	1.461086e-02	1.835	0	0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	R-HSA-8864260	1.654778e-02	1.781	0	0
Synthesis of PIPs at the plasma membrane	R-HSA-1660499	1.672103e-02	1.777	0	0
Developmental Lineage of Mammary Gland Myoepithelial Cells	R-HSA-9927432	1.687242e-02	1.773	0	0
Polo-like kinase mediated events	R-HSA-156711	1.705817e-02	1.768	0	0
Ephrin signaling	R-HSA-3928664	1.705817e-02	1.768	0	0
PKA activation	R-HSA-163615	1.705817e-02	1.768	0	0
PKA activation in glucagon signalling	R-HSA-164378	1.705817e-02	1.768	0	0
Transcriptional activation of p53 responsive genes	R-HSA-69560	1.917532e-02	1.717	0	0
Transcriptional activation of cell cycle inhibitor p21	R-HSA-69895	1.917532e-02	1.717	0	0
TLR3-mediated TICAM1-dependent programmed cell death	R-HSA-9013957	1.917532e-02	1.717	0	0
Regulation of NFE2L2 gene expression	R-HSA-9818749	1.878501e-02	1.726	0	0
p75NTR recruits signalling complexes	R-HSA-209543	1.964836e-02	1.707	0	0
Regulation of FOXO transcriptional activity by acetylation	R-HSA-9617629	1.964836e-02	1.707	0	0
Loss of function of MECP2 in Rett syndrome	R-HSA-9005891	1.964836e-02	1.707	0	0
Pervasive developmental disorders	R-HSA-9005895	1.964836e-02	1.707	0	0
Disorders of Nervous System Development	R-HSA-9697154	1.964836e-02	1.707	0	0
IRAK1 recruits IKK complex	R-HSA-937039	1.964836e-02	1.707	0	0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	R-HSA-975144	1.964836e-02	1.707	0	0
Signaling by CTNNB1 phospho-site mutants	R-HSA-4839743	1.964836e-02	1.707	0	0
CTNNB1 S37 mutants aren't phosphorylated	R-HSA-5358749	1.964836e-02	1.707	0	0
CTNNB1 T41 mutants aren't phosphorylated	R-HSA-5358752	1.964836e-02	1.707	0	0
CTNNB1 S33 mutants aren't phosphorylated	R-HSA-5358747	1.964836e-02	1.707	0	0
CTNNB1 S45 mutants aren't phosphorylated	R-HSA-5358751	1.964836e-02	1.707	0	0
Ras activation upon Ca2+ influx through NMDA receptor	R-HSA-442982	1.736311e-02	1.760	0	0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	R-HSA-5693554	1.725634e-02	1.763	0	0
G1/S DNA Damage Checkpoints	R-HSA-69615	1.908138e-02	1.719	1	0
Ub-specific processing proteases	R-HSA-5689880	1.760188e-02	1.754	0	0
Resolution of D-Loop Structures	R-HSA-5693537	1.955093e-02	1.709	0	0
Cyclin A:Cdk2-associated events at S phase entry	R-HSA-69656	1.847212e-02	1.733	0	0
Estrogen-dependent gene expression	R-HSA-9018519	1.932980e-02	1.714	0	0
Long-term potentiation	R-HSA-9620244	1.725634e-02	1.763	0	0
Signaling by Receptor Tyrosine Kinases	R-HSA-9006934	1.882016e-02	1.725	1	0
Negative regulation of NMDA receptor-mediated neuronal transmission	R-HSA-9617324	1.736311e-02	1.760	0	0
Regulation of Glucokinase by Glucokinase Regulatory Protein	R-HSA-170822	1.955093e-02	1.709	0	0
Regulated Necrosis	R-HSA-5218859	2.001940e-02	1.699	0	0
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	2.051177e-02	1.688	0	0
MAP2K and MAPK activation	R-HSA-5674135	2.062485e-02	1.686	0	0
TRP channels	R-HSA-3295583	2.115212e-02	1.675	0	0
Developmental Lineage of Mammary Stem Cells	R-HSA-9938206	2.161822e-02	1.665	0	0
IKK complex recruitment mediated by RIP1	R-HSA-937041	2.168330e-02	1.664	0	0
Rev-mediated nuclear export of HIV RNA	R-HSA-165054	2.194589e-02	1.659	0	0
TICAM1,TRAF6-dependent induction of TAK1 complex	R-HSA-9014325	2.364346e-02	1.626	0	0
Establishment of Sister Chromatid Cohesion	R-HSA-2468052	2.364346e-02	1.626	0	0
Folding of actin by CCT/TriC	R-HSA-390450	2.364346e-02	1.626	0	0
Trafficking of AMPA receptors	R-HSA-399719	2.451682e-02	1.611	0	0
HDACs deacetylate histones	R-HSA-3214815	2.227612e-02	1.652	0	0
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	2.550076e-02	1.593	0	0
Pexophagy	R-HSA-9664873	2.364346e-02	1.626	0	0
Defective Intrinsic Pathway for Apoptosis	R-HSA-9734009	2.565826e-02	1.591	0	0
Degradation of beta-catenin by the destruction complex	R-HSA-195253	2.550076e-02	1.593	0	0
Deubiquitination	R-HSA-5688426	2.583389e-02	1.588	0	0
Josephin domain DUBs	R-HSA-5689877	2.364346e-02	1.626	0	0
HIV Life Cycle	R-HSA-162587	2.264052e-02	1.645	0	0
Budding and maturation of HIV virion	R-HSA-162588	2.451682e-02	1.611	0	0
Kinesins	R-HSA-983189	2.349876e-02	1.629	0	0
Reproduction	R-HSA-1474165	2.492313e-02	1.603	0	0
Positive Regulation of CDH1 Gene Transcription	R-HSA-9764790	2.364346e-02	1.626	0	0
CaMK IV-mediated phosphorylation of CREB	R-HSA-111932	2.364346e-02	1.626	0	0
Signaling by ALK	R-HSA-201556	2.574605e-02	1.589	0	0
NS1 Mediated Effects on Host Pathways	R-HSA-168276	2.574605e-02	1.589	0	0
Nuclear import of Rev protein	R-HSA-180746	2.325766e-02	1.633	0	0
Formation of the non-canonical BAF (ncBAF) complex	R-HSA-9933947	2.613325e-02	1.583	0	0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	R-HSA-9659787	2.613325e-02	1.583	0	0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	R-HSA-9661069	2.613325e-02	1.583	0	0
MAP kinase activation	R-HSA-450294	2.667009e-02	1.574	0	0
Drug resistance in ERBB2 KD mutants	R-HSA-9665230	3.045354e-02	1.516	0	0
Drug-mediated inhibition of ERBB2 signaling	R-HSA-9652282	3.045354e-02	1.516	0	0
RUNX3 regulates RUNX1-mediated transcription	R-HSA-8951911	3.045354e-02	1.516	0	0
Resistance of ERBB2 KD mutants to sapitinib	R-HSA-9665244	3.045354e-02	1.516	0	0
Resistance of ERBB2 KD mutants to afatinib	R-HSA-9665249	3.045354e-02	1.516	0	0
Resistance of ERBB2 KD mutants to trastuzumab	R-HSA-9665233	3.045354e-02	1.516	0	0
Resistance of ERBB2 KD mutants to lapatinib	R-HSA-9665251	3.045354e-02	1.516	0	0
Resistance of ERBB2 KD mutants to neratinib	R-HSA-9665246	3.045354e-02	1.516	0	0
Resistance of ERBB2 KD mutants to osimertinib	R-HSA-9665247	3.045354e-02	1.516	0	0
Drug resistance in ERBB2 TMD/JMD mutants	R-HSA-9665737	3.045354e-02	1.516	0	0
Resistance of ERBB2 KD mutants to tesevatinib	R-HSA-9665245	3.045354e-02	1.516	0	0
Resistance of ERBB2 KD mutants to AEE788	R-HSA-9665250	3.045354e-02	1.516	0	0
RUNX2 regulates chondrocyte maturation	R-HSA-8941284	3.124615e-02	1.505	0	0
Binding of TCF/LEF:CTNNB1 to target gene promoters	R-HSA-4411364	2.784606e-02	1.555	0	0
TRIF-mediated programmed cell death	R-HSA-2562578	2.784606e-02	1.555	0	0
Signaling by APC mutants	R-HSA-4839744	3.218567e-02	1.492	0	0
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	3.218567e-02	1.492	0	0
Truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	3.218567e-02	1.492	0	0
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	3.218567e-02	1.492	0	0
Disorders of Developmental Biology	R-HSA-9675151	2.711378e-02	1.567	0	0
Transcription of E2F targets under negative control by DREAM complex	R-HSA-1362277	2.714531e-02	1.566	0	0
Diseases of mitotic cell cycle	R-HSA-9675126	2.917262e-02	1.535	0	0
Neurodegenerative Diseases	R-HSA-8863678	3.231521e-02	1.491	0	0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	R-HSA-8862803	3.231521e-02	1.491	0	0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	R-HSA-8866910	2.711378e-02	1.567	0	0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	R-HSA-936964	2.711378e-02	1.567	0	0
RAB GEFs exchange GTP for GDP on RABs	R-HSA-8876198	3.061135e-02	1.514	0	0
Formation of WDR5-containing histone-modifying complexes	R-HSA-9772755	2.746124e-02	1.561	0	0
UCH proteinases	R-HSA-5689603	2.941266e-02	1.531	0	0
Activation of PUMA and translocation to mitochondria	R-HSA-139915	2.784606e-02	1.555	0	0
RAF/MAP kinase cascade	R-HSA-5673001	2.959302e-02	1.529	0	0
Autophagy	R-HSA-9612973	3.091194e-02	1.510	0	0
Intra-Golgi and retrograde Golgi-to-ER traffic	R-HSA-6811442	2.817555e-02	1.550	0	0
TGF-beta receptor signaling activates SMADs	R-HSA-2173789	2.791656e-02	1.554	0	0
Regulation of Homotypic Cell-Cell Adhesion	R-HSA-9759476	3.049450e-02	1.516	0	0
Cell junction organization	R-HSA-446728	2.892451e-02	1.539	0	0
Cell-Cell communication	R-HSA-1500931	3.024928e-02	1.519	0	0
Smooth Muscle Contraction	R-HSA-445355	3.141333e-02	1.503	0	0
RET signaling	R-HSA-8853659	3.219512e-02	1.492	0	0
Host Interactions of HIV factors	R-HSA-162909	2.953561e-02	1.530	0	0
Interactions of Rev with host cellular proteins	R-HSA-177243	3.001245e-02	1.523	0	0
Interleukin-12 signaling	R-HSA-9020591	2.941266e-02	1.531	0	0
MAPK1/MAPK3 signaling	R-HSA-5684996	3.246056e-02	1.489	0	0
Gene expression (Transcription)	R-HSA-74160	3.295262e-02	1.482	1	0
RNA Polymerase II Transcription	R-HSA-73857	3.319868e-02	1.479	1	0
Transport of Mature Transcript to Cytoplasm	R-HSA-72202	3.339502e-02	1.476	0	0
TNFR1-induced proapoptotic signaling	R-HSA-5357786	3.351023e-02	1.475	0	0
PKA-mediated phosphorylation of CREB	R-HSA-111931	3.351023e-02	1.475	0	0
NRIF signals cell death from the nucleus	R-HSA-205043	3.394259e-02	1.469	0	0
Formation of the polybromo-BAF (pBAF) complex	R-HSA-9933939	3.394259e-02	1.469	0	0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	R-HSA-975163	3.394259e-02	1.469	0	0
MAP3K8 (TPL2)-dependent MAPK1/3 activation	R-HSA-5684264	3.394259e-02	1.469	0	0
Signaling by Hedgehog	R-HSA-5358351	3.433460e-02	1.464	0	0
Glutamate binding, activation of AMPA receptors and synaptic plasticity	R-HSA-399721	3.443540e-02	1.463	0	0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	R-HSA-442742	3.443540e-02	1.463	0	0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	R-HSA-8939243	3.443540e-02	1.463	0	0
Transcriptional Regulation by VENTX	R-HSA-8853884	3.477356e-02	1.459	0	0
HATs acetylate histones	R-HSA-3214847	3.480344e-02	1.458	0	0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	R-HSA-8936459	3.495405e-02	1.457	0	0
Sensory processing of sound by inner hair cells of the cochlea	R-HSA-9662360	3.495405e-02	1.457	0	0
Alternative Lengthening of Telomeres (ALT)	R-HSA-9006821	4.488726e-02	1.348	0	0
Defective Inhibition of DNA Recombination at Telomere	R-HSA-9670621	4.488726e-02	1.348	0	0
Diseases of Telomere Maintenance	R-HSA-9673013	4.488726e-02	1.348	0	0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations	R-HSA-9670615	4.488726e-02	1.348	0	0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	R-HSA-9670613	4.488726e-02	1.348	0	0
Loss of MECP2 binding ability to 5hmC-DNA	R-HSA-9022534	4.488726e-02	1.348	0	0
Myoclonic epilepsy of Lafora	R-HSA-3785653	3.928295e-02	1.406	0	0
NF-kB is activated and signals survival	R-HSA-209560	4.251567e-02	1.371	0	0
Sema3A PAK dependent Axon repulsion	R-HSA-399954	4.316448e-02	1.365	0	0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	R-HSA-2173791	4.316448e-02	1.365	0	0
TRAF6-mediated induction of TAK1 complex within TLR4 complex	R-HSA-937072	4.316448e-02	1.365	0	0
Formation of the embryonic stem cell BAF (esBAF) complex	R-HSA-9933946	4.316448e-02	1.365	0	0
Beta-catenin phosphorylation cascade	R-HSA-196299	4.316448e-02	1.365	0	0
Signaling by cytosolic FGFR1 fusion mutants	R-HSA-1839117	4.239249e-02	1.373	0	0
Degradation of GLI1 by the proteasome	R-HSA-5610780	4.005617e-02	1.397	0	0
Regulation of RAS by GAPs	R-HSA-5658442	3.879698e-02	1.411	0	0
Activation of NF-kappaB in B cells	R-HSA-1169091	4.396718e-02	1.357	0	0
Transcriptional regulation by RUNX2	R-HSA-8878166	4.481444e-02	1.349	0	0
Transcriptional regulation of pluripotent stem cells	R-HSA-452723	4.337770e-02	1.363	0	0
TCR signaling	R-HSA-202403	4.163860e-02	1.381	0	0
MyD88-independent TLR4 cascade	R-HSA-166166	4.163860e-02	1.381	0	0
TRIF (TICAM1)-mediated TLR4 signaling	R-HSA-937061	4.163860e-02	1.381	0	0
Cyclin E associated events during G1/S transition	R-HSA-69202	4.348707e-02	1.362	0	0
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	4.169901e-02	1.380	0	0
PIP3 activates AKT signaling	R-HSA-1257604	4.085277e-02	1.389	0	0
activated TAK1 mediates p38 MAPK activation	R-HSA-450302	4.083663e-02	1.389	0	0
Clathrin-mediated endocytosis	R-HSA-8856828	3.677647e-02	1.434	0	0
HIV Infection	R-HSA-162906	4.372377e-02	1.359	0	0
Macroautophagy	R-HSA-1632852	4.303541e-02	1.366	0	0
STAT3 nuclear events downstream of ALK signaling	R-HSA-9701898	4.316448e-02	1.365	0	0
Signaling by NOTCH3	R-HSA-9012852	4.033314e-02	1.394	0	0
Spry regulation of FGF signaling	R-HSA-1295596	4.316448e-02	1.365	0	0
Cell-extracellular matrix interactions	R-HSA-446353	4.316448e-02	1.365	0	0
Vpr-mediated nuclear import of PICs	R-HSA-180910	3.749087e-02	1.426	0	0
Interleukin-12 family signaling	R-HSA-447115	3.742058e-02	1.427	0	0
Activation of NMDA receptors and postsynaptic events	R-HSA-442755	4.549980e-02	1.342	0	0
PI Metabolism	R-HSA-1483255	4.549980e-02	1.342	0	0
Signaling by EGFR in Cancer	R-HSA-1643713	4.626780e-02	1.335	0	0
Activated NOTCH1 Transmits Signal to the Nucleus	R-HSA-2122948	4.626780e-02	1.335	0	0
PLC beta mediated events	R-HSA-112043	4.659990e-02	1.332	0	0
NOD1/2 Signaling Pathway	R-HSA-168638	4.691897e-02	1.329	0	0
Signaling by MAPK mutants	R-HSA-9652817	4.692664e-02	1.329	0	0
Maturation of protein E	R-HSA-9694493	4.692664e-02	1.329	0	0
Maturation of protein E	R-HSA-9683683	4.692664e-02	1.329	0	0
AURKA Activation by TPX2	R-HSA-8854518	4.754172e-02	1.323	0	0
Adherens junctions interactions	R-HSA-418990	4.793882e-02	1.319	0	0
Downregulation of TGF-beta receptor signaling	R-HSA-2173788	4.917421e-02	1.308	0	0
NOTCH3 Activation and Transmission of Signal to the Nucleus	R-HSA-9013507	4.917421e-02	1.308	0	0
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	4.966030e-02	1.304	0	0
Expression of BMAL (ARNTL), CLOCK, and NPAS2	R-HSA-9931509	4.988198e-02	1.302	0	0
Rap1 signalling	R-HSA-392517	5.181730e-02	1.286	0	0
Signaling by FGFR4	R-HSA-5654743	5.228262e-02	1.282	0	0
Loss of MECP2 binding ability to 5mC-DNA	R-HSA-9022538	5.273744e-02	1.278	0	0
GP1b-IX-V activation signalling	R-HSA-430116	5.320395e-02	1.274	0	0
IRAK2 mediated activation of TAK1 complex	R-HSA-937042	5.320395e-02	1.274	0	0
Caspase-mediated cleavage of cytoskeletal proteins	R-HSA-264870	5.320395e-02	1.274	0	0
Regulation of mRNA stability by proteins that bind AU-rich elements	R-HSA-450531	5.343547e-02	1.272	0	0
Negative regulation of FLT3	R-HSA-9706369	5.386519e-02	1.269	0	0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	R-HSA-9860927	5.419937e-02	1.266	0	0
CD28 dependent PI3K/Akt signaling	R-HSA-389357	5.457027e-02	1.263	0	0
AKT phosphorylates targets in the cytosol	R-HSA-198323	5.471407e-02	1.262	0	0
Constitutive Signaling by Overexpressed ERBB2	R-HSA-9634285	5.471407e-02	1.262	0	0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	R-HSA-9820865	5.471407e-02	1.262	0	0
Signaling by LTK	R-HSA-9842663	5.471407e-02	1.262	0	0
Signaling by NOTCH1 HD Domain Mutants in Cancer	R-HSA-2691230	5.471407e-02	1.262	0	0
Constitutive Signaling by NOTCH1 HD Domain Mutants	R-HSA-2691232	5.471407e-02	1.262	0	0
Signaling by Interleukins	R-HSA-449147	5.540458e-02	1.256	0	0
Golgi Associated Vesicle Biogenesis	R-HSA-432722	5.574060e-02	1.254	0	0
Epigenetic regulation of gene expression	R-HSA-212165	5.601265e-02	1.252	0	0
Formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	5.693438e-02	1.245	0	0
Glucose metabolism	R-HSA-70326	5.702513e-02	1.244	0	0
Interactions of Vpr with host cellular proteins	R-HSA-176033	5.702690e-02	1.244	0	0
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	5.784330e-02	1.238	0	0
Loss of Nlp from mitotic centrosomes	R-HSA-380259	5.784330e-02	1.238	0	0
CREB phosphorylation	R-HSA-199920	6.623441e-02	1.179	0	0
RUNX1 regulates transcription of genes involved in WNT signaling	R-HSA-8939256	6.623441e-02	1.179	0	0
RAS signaling downstream of NF1 loss-of-function variants	R-HSA-6802953	6.623441e-02	1.179	0	0
Regulation of TP53 Activity through Association with Co-factors	R-HSA-6804759	6.882207e-02	1.162	0	0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	R-HSA-9934037	6.249313e-02	1.204	0	0
APC-Cdc20 mediated degradation of Nek2A	R-HSA-179409	7.444578e-02	1.128	0	0
Termination of translesion DNA synthesis	R-HSA-5656169	7.397445e-02	1.131	0	0
Activation of ATR in response to replication stress	R-HSA-176187	6.784655e-02	1.168	1	1
RUNX2 regulates bone development	R-HSA-8941326	6.220497e-02	1.206	0	0
Deposition of new CENPA-containing nucleosomes at the centromere	R-HSA-606279	6.685974e-02	1.175	0	0
Nucleosome assembly	R-HSA-774815	6.685974e-02	1.175	0	0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	R-HSA-5693565	6.338893e-02	1.198	0	0
Transport of Mature mRNA derived from an Intron-Containing Transcript	R-HSA-159236	5.897048e-02	1.229	0	0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	R-HSA-2173796	7.095447e-02	1.149	0	0
p53-Dependent G1/S DNA damage checkpoint	R-HSA-69580	6.102452e-02	1.214	0	0
p53-Dependent G1 DNA Damage Response	R-HSA-69563	6.102452e-02	1.214	0	0
Cyclin D associated events in G1	R-HSA-69231	5.926860e-02	1.227	0	0
G1 Phase	R-HSA-69236	5.926860e-02	1.227	0	0
Mitotic G1 phase and G1/S transition	R-HSA-453279	6.523327e-02	1.186	0	0
Epigenetic regulation by WDR5-containing histone modifying complexes	R-HSA-9917777	7.758794e-02	1.110	0	0
Signaling by TGF-beta Receptor Complex in Cancer	R-HSA-3304351	6.623441e-02	1.179	0	0
G0 and Early G1	R-HSA-1538133	5.884188e-02	1.230	0	0
Interleukin-6 signaling	R-HSA-1059683	6.882207e-02	1.162	0	0
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	7.536937e-02	1.123	0	0
MyD88 cascade initiated on plasma membrane	R-HSA-975871	7.536937e-02	1.123	0	0
Golgi Cisternae Pericentriolar Stack Reorganization	R-HSA-162658	6.882207e-02	1.162	0	0
Golgi-to-ER retrograde transport	R-HSA-8856688	6.368598e-02	1.196	0	0
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	7.536937e-02	1.123	0	0
PKMTs methylate histone lysines	R-HSA-3214841	6.483205e-02	1.188	0	0
Meiosis	R-HSA-1500620	7.091851e-02	1.149	0	0
Membrane binding and targetting of GAG proteins	R-HSA-174490	6.882207e-02	1.162	0	0
Signaling by WNT in cancer	R-HSA-4791275	5.884188e-02	1.230	0	0
AUF1 (hnRNP D0) binds and destabilizes mRNA	R-HSA-450408	6.220497e-02	1.206	0	0
Ovarian tumor domain proteases	R-HSA-5689896	7.095447e-02	1.149	0	0
Signaling by ROBO receptors	R-HSA-376176	6.468439e-02	1.189	0	0
CREB1 phosphorylation through the activation of Adenylate Cyclase	R-HSA-442720	6.882207e-02	1.162	0	0
Negative regulation of MET activity	R-HSA-6807004	6.249313e-02	1.204	0	0
Interleukin-17 signaling	R-HSA-448424	7.112555e-02	1.148	0	0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	R-HSA-9856530	7.113541e-02	1.148	0	0
Negative regulation of FGFR4 signaling	R-HSA-5654733	7.397445e-02	1.131	0	0
Negative Regulation of CDH1 Gene Transcription	R-HSA-9764725	7.032478e-02	1.153	0	0
Cell-cell junction organization	R-HSA-421270	6.721959e-02	1.173	0	0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	6.411774e-02	1.193	0	0
Sensory processing of sound	R-HSA-9659379	6.500773e-02	1.187	0	0
Regulation of PTEN gene transcription	R-HSA-8943724	7.032478e-02	1.153	0	0
Cyclin A/B1/B2 associated events during G2/M transition	R-HSA-69273	6.784655e-02	1.168	0	0
SARS-CoV-2 activates/modulates innate and adaptive immune responses	R-HSA-9705671	7.073286e-02	1.150	0	0
FLT3 signaling in disease	R-HSA-9682385	6.220497e-02	1.206	0	0
Export of Viral Ribonucleoproteins from Nucleus	R-HSA-168274	7.506957e-02	1.125	0	0
Transport of Ribonucleoproteins into the Host Nucleus	R-HSA-168271	6.483205e-02	1.188	0	0
DNA Damage Recognition in GG-NER	R-HSA-5696394	7.769364e-02	1.110	0	0
Association of TriC/CCT with target proteins during biosynthesis	R-HSA-390471	7.769364e-02	1.110	0	0
SWI/SNF chromatin remodelers	R-HSA-9932451	8.059578e-02	1.094	0	0
ATP-dependent chromatin remodelers	R-HSA-9932444	8.059578e-02	1.094	0	0
MTF1 activates gene expression	R-HSA-5660489	8.089644e-02	1.092	0	0
RUNX2 regulates genes involved in differentiation of myeloid cells	R-HSA-8941333	8.089644e-02	1.092	0	0
RUNX3 regulates BCL2L11 (BIM) transcription	R-HSA-8952158	8.089644e-02	1.092	0	0
GRB7 events in ERBB2 signaling	R-HSA-1306955	8.089644e-02	1.092	0	0
p75NTR negatively regulates cell cycle via SC1	R-HSA-193670	8.089644e-02	1.092	0	0
Signaling by TGFB family members	R-HSA-9006936	8.093929e-02	1.092	0	0
Formation of the canonical BAF (cBAF) complex	R-HSA-9933937	8.484155e-02	1.071	0	0
Synthesis And Processing Of GAG, GAGPOL Polyproteins	R-HSA-174495	8.484155e-02	1.071	0	0
SHC1 events in ERBB2 signaling	R-HSA-1250196	8.511008e-02	1.070	0	0
Aberrant regulation of mitotic cell cycle due to RB1 defects	R-HSA-9687139	8.511008e-02	1.070	0	0
Activation of BH3-only proteins	R-HSA-114452	8.511008e-02	1.070	0	0
Transcriptional regulation by small RNAs	R-HSA-5578749	8.545987e-02	1.068	0	0
trans-Golgi Network Vesicle Budding	R-HSA-199992	8.545987e-02	1.068	0	0
G-protein mediated events	R-HSA-112040	8.567370e-02	1.067	0	0
Signaling by NOTCH	R-HSA-157118	8.698647e-02	1.061	0	0
Dual Incision in GG-NER	R-HSA-5696400	8.839307e-02	1.054	0	0
Regulation of localization of FOXO transcription factors	R-HSA-9614399	8.856562e-02	1.053	0	0
InlA-mediated entry of Listeria monocytogenes into host cells	R-HSA-8876493	8.856562e-02	1.053	0	0
RHOBTB3 ATPase cycle	R-HSA-9706019	8.856562e-02	1.053	0	0
Alpha-protein kinase 1 signaling pathway	R-HSA-9645460	8.856562e-02	1.053	0	0
Role of ABL in ROBO-SLIT signaling	R-HSA-428890	8.903827e-02	1.050	0	0
Interactions of Tat with host cellular proteins	R-HSA-176034	9.070825e-02	1.042	0	0
TWIK-releated acid-sensitive K+ channel (TASK)	R-HSA-1299316	9.070825e-02	1.042	0	0
IKBKB deficiency causes SCID	R-HSA-5602636	9.070825e-02	1.042	0	0
Signaling by TCF7L2 mutants	R-HSA-5339700	9.070825e-02	1.042	0	0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	R-HSA-5603027	9.070825e-02	1.042	0	0
Signaling by SCF-KIT	R-HSA-1433557	9.234509e-02	1.035	1	1
TBC/RABGAPs	R-HSA-8854214	9.234509e-02	1.035	0	0
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	9.328729e-02	1.030	0	0
GPER1 signaling	R-HSA-9634597	9.338219e-02	1.030	0	0
Co-stimulation by CD28	R-HSA-389356	9.338219e-02	1.030	0	0
TCF dependent signaling in response to WNT	R-HSA-201681	9.381951e-02	1.028	0	0
Meiotic synapsis	R-HSA-1221632	9.396418e-02	1.027	0	0
Signaling by ERBB2 ECD mutants	R-HSA-9665348	9.514600e-02	1.022	0	0
Synaptic adhesion-like molecules	R-HSA-8849932	9.514600e-02	1.022	0	0
Serotonin Neurotransmitter Release Cycle	R-HSA-181429	9.514600e-02	1.022	0	0
COPI-dependent Golgi-to-ER retrograde traffic	R-HSA-6811434	9.582259e-02	1.019	0	0
EGFR downregulation	R-HSA-182971	9.720935e-02	1.012	0	0
Formation of Incision Complex in GG-NER	R-HSA-5696395	1.017758e-01	0.992	0	0
mTORC1-mediated signalling	R-HSA-166208	1.022024e-01	0.991	0	0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	R-HSA-6803205	1.022024e-01	0.991	0	0
Dopamine Neurotransmitter Release Cycle	R-HSA-212676	1.022024e-01	0.991	0	0
S Phase	R-HSA-69242	1.022483e-01	0.990	0	0
Translesion synthesis by REV1	R-HSA-110312	1.027368e-01	0.988	0	0
InlB-mediated entry of Listeria monocytogenes into host cell	R-HSA-8875360	1.027368e-01	0.988	0	0
Inositol phosphate metabolism	R-HSA-1483249	1.051606e-01	0.978	0	0
DNA Repair	R-HSA-73894	1.051690e-01	0.978	1	0
PTEN Regulation	R-HSA-6807070	1.064105e-01	0.973	0	0
Activation of RAC1	R-HSA-428540	1.098723e-01	0.959	0	0
Centrosome maturation	R-HSA-380287	1.102794e-01	0.958	0	0
Regulation of signaling by CBL	R-HSA-912631	1.119469e-01	0.951	0	0
Germ layer formation at gastrulation	R-HSA-9754189	1.119469e-01	0.951	0	0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A	R-HSA-69601	1.141624e-01	0.942	1	1
p53-Independent G1/S DNA Damage Checkpoint	R-HSA-69613	1.141624e-01	0.942	1	0
Signaling by FGFR3	R-HSA-5654741	1.141624e-01	0.942	0	0
NEP/NS2 Interacts with the Cellular Export Machinery	R-HSA-168333	1.141624e-01	0.942	0	0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	R-HSA-3134973	1.141732e-01	0.942	0	0
Loss of Function of TGFBR1 in Cancer	R-HSA-3656534	1.141732e-01	0.942	0	0
Loss of phosphorylation of MECP2 at T308	R-HSA-9022535	1.141732e-01	0.942	0	0
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	1.143585e-01	0.942	0	0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	1.144203e-01	0.941	0	0
Vesicle-mediated transport	R-HSA-5653656	1.144309e-01	0.941	0	0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	R-HSA-442729	1.150879e-01	0.939	0	0
Co-stimulation by ICOS	R-HSA-9927354	1.150879e-01	0.939	0	0
Apoptotic cleavage of cell adhesion proteins	R-HSA-351906	1.150879e-01	0.939	0	0
Modulation by Mtb of host immune system	R-HSA-9637628	1.150879e-01	0.939	0	0
Hedgehog 'on' state	R-HSA-5632684	1.210017e-01	0.917	0	0
KEAP1-NFE2L2 pathway	R-HSA-9755511	1.210156e-01	0.917	0	0
Phase 0 - rapid depolarisation	R-HSA-5576892	1.218678e-01	0.914	0	0
Negative regulation of FGFR3 signaling	R-HSA-5654732	1.218678e-01	0.914	0	0
MyD88 dependent cascade initiated on endosome	R-HSA-975155	1.221480e-01	0.913	0	0
Translesion synthesis by POLI	R-HSA-5656121	1.224372e-01	0.912	0	0
TP53 Regulates Transcription of Caspase Activators and Caspases	R-HSA-6803207	1.224372e-01	0.912	0	0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	R-HSA-9634600	1.224372e-01	0.912	0	0
ESR-mediated signaling	R-HSA-8939211	1.251560e-01	0.903	0	0
GLI3 is processed to GLI3R by the proteasome	R-HSA-5610785	1.261475e-01	0.899	0	0
Degradation of GLI2 by the proteasome	R-HSA-5610783	1.261475e-01	0.899	0	0
Assembly and cell surface presentation of NMDA receptors	R-HSA-9609736	1.261475e-01	0.899	0	0
Formation of definitive endoderm	R-HSA-9823730	1.302009e-01	0.885	0	0
Nephrin family interactions	R-HSA-373753	1.302009e-01	0.885	0	0
DNA Double Strand Break Response	R-HSA-5693606	1.328928e-01	0.876	0	0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	R-HSA-9027276	1.334113e-01	0.875	0	0
RUNX3 regulates NOTCH signaling	R-HSA-8941856	1.334113e-01	0.875	0	0
VLDLR internalisation and degradation	R-HSA-8866427	1.334113e-01	0.875	0	0
Deadenylation of mRNA	R-HSA-429947	1.349669e-01	0.870	0	0
CD209 (DC-SIGN) signaling	R-HSA-5621575	1.349669e-01	0.870	0	0
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	1.356355e-01	0.868	0	0
Deletions in the AXIN1 gene destabilize the destruction complex	R-HSA-5467345	1.540044e-01	0.812	0	0
APC truncation mutants are not K63 polyubiquitinated	R-HSA-5467333	1.540044e-01	0.812	0	0
Loss of Function of TP53 in Cancer	R-HSA-9723907	1.540044e-01	0.812	0	0
Loss of function of TP53 in cancer due to loss of tetramerization ability	R-HSA-9723905	1.540044e-01	0.812	0	0
Defective translocation of RB1 mutants to the nucleus	R-HSA-9661070	1.540044e-01	0.812	0	0
Deletions in the AMER1 gene destabilize the destruction complex	R-HSA-5467343	1.540044e-01	0.812	0	0
Regulation of cortical dendrite branching	R-HSA-8985801	1.450705e-01	0.838	0	0
TGFBR1 LBD Mutants in Cancer	R-HSA-3656535	1.450705e-01	0.838	0	0
RUNX1 regulates expression of components of tight junctions	R-HSA-8935964	1.516611e-01	0.819	0	0
CLEC7A/inflammasome pathway	R-HSA-5660668	1.516611e-01	0.819	0	0
Negative feedback regulation of MAPK pathway	R-HSA-5674499	1.516611e-01	0.819	0	0
IkBA variant leads to EDA-ID	R-HSA-5603029	1.516611e-01	0.819	0	0
Loss of Function of SMAD2/3 in Cancer	R-HSA-3304349	1.516611e-01	0.819	0	0
NFE2L2 regulating MDR associated enzymes	R-HSA-9818032	1.440442e-01	0.842	0	0
AKT phosphorylates targets in the nucleus	R-HSA-198693	1.440442e-01	0.842	0	0
Calcineurin activates NFAT	R-HSA-2025928	1.440442e-01	0.842	0	0
ALK mutants bind TKIs	R-HSA-9700645	1.440442e-01	0.842	0	0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	R-HSA-8869496	1.924055e-01	0.716	0	0
HDR through MMEJ (alt-NHEJ)	R-HSA-5685939	1.589865e-01	0.799	0	0
Translesion synthesis by POLK	R-HSA-5655862	1.438414e-01	0.842	0	0
Constitutive Signaling by EGFRvIII	R-HSA-5637810	1.668215e-01	0.778	0	0
Signaling by EGFRvIII in Cancer	R-HSA-5637812	1.668215e-01	0.778	0	0
NOTCH2 Activation and Transmission of Signal to the Nucleus	R-HSA-2979096	1.498362e-01	0.824	0	0
Endosomal Sorting Complex Required For Transport (ESCRT)	R-HSA-917729	1.377574e-01	0.861	0	0
Signaling by ERBB2 in Cancer	R-HSA-1227990	1.546554e-01	0.811	0	0
Regulation of RUNX1 Expression and Activity	R-HSA-8934593	1.723760e-01	0.764	0	0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	R-HSA-9843970	1.550070e-01	0.810	0	0
Vif-mediated degradation of APOBEC3G	R-HSA-180585	1.891455e-01	0.723	0	0
Nonhomologous End-Joining (NHEJ)	R-HSA-5693571	1.520189e-01	0.818	0	0
Translation initiation complex formation	R-HSA-72649	1.634596e-01	0.787	0	0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)	R-HSA-9845323	1.739229e-01	0.760	0	0
RUNX1 regulates transcription of genes involved in differentiation of HSCs	R-HSA-8939236	1.467436e-01	0.833	0	0
Regulation of RUNX2 expression and activity	R-HSA-8939902	1.875448e-01	0.727	0	0
Recruitment of NuMA to mitotic centrosomes	R-HSA-380320	1.439082e-01	0.842	0	0
Regulation of endogenous retroelements	R-HSA-9842860	1.445356e-01	0.840	0	0
Nuclear Receptor transcription pathway	R-HSA-383280	2.005975e-01	0.698	0	0
Nuclear events mediated by NFE2L2	R-HSA-9759194	2.002449e-01	0.698	0	0
Regulation of PD-L1(CD274) expression	R-HSA-9909648	1.608244e-01	0.794	0	0
Downstream TCR signaling	R-HSA-202424	1.643993e-01	0.784	0	0
Stabilization of p53	R-HSA-69541	1.545381e-01	0.811	0	0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	1.865412e-01	0.729	0	0
Signaling by EGFR	R-HSA-177929	1.915888e-01	0.718	0	0
G1/S Transition	R-HSA-69206	1.952534e-01	0.709	0	0
Defective RIPK1-mediated regulated necrosis	R-HSA-9693928	1.755075e-01	0.756	0	0
The role of GTSE1 in G2/M progression after G2 checkpoint	R-HSA-8852276	2.016643e-01	0.695	0	0
DNA Damage/Telomere Stress Induced Senescence	R-HSA-2559586	2.016643e-01	0.695	0	0
Netrin-1 signaling	R-HSA-373752	1.682194e-01	0.774	0	0
Fanconi Anemia Pathway	R-HSA-6783310	1.836218e-01	0.736	0	0
Diseases of programmed cell death	R-HSA-9645723	1.439082e-01	0.842	0	0
DARPP-32 events	R-HSA-180024	1.377574e-01	0.861	0	0
Glucagon signaling in metabolic regulation	R-HSA-163359	1.391927e-01	0.856	0	0
Signaling by FGFR1	R-HSA-5654736	1.915888e-01	0.718	0	0
Formation of intermediate mesoderm	R-HSA-9761174	1.755075e-01	0.756	0	0
Interleukin-3, Interleukin-5 and GM-CSF signaling	R-HSA-512988	1.394555e-01	0.856	0	0
Listeria monocytogenes entry into host cells	R-HSA-8876384	1.707631e-01	0.768	0	0
Negative regulators of DDX58/IFIH1 signaling	R-HSA-936440	1.725119e-01	0.763	0	0
Signaling by FGFR1 in disease	R-HSA-5655302	2.035983e-01	0.691	0	0
ZBP1(DAI) mediated induction of type I IFNs	R-HSA-1606322	1.912275e-01	0.718	0	0
Signaling by WNT	R-HSA-195721	1.553303e-01	0.809	0	0
Meiotic recombination	R-HSA-912446	1.956396e-01	0.709	0	0
Regulation of innate immune responses to cytosolic DNA	R-HSA-3134975	1.438414e-01	0.842	0	0
RAF-independent MAPK1/3 activation	R-HSA-112409	1.928767e-01	0.715	0	0
Evasion by RSV of host interferon responses	R-HSA-9833109	1.725119e-01	0.763	0	0
Neuronal System	R-HSA-112316	1.634032e-01	0.787	0	0
L1CAM interactions	R-HSA-373760	1.526643e-01	0.816	0	0
PKA-mediated phosphorylation of key metabolic factors	R-HSA-163358	1.516611e-01	0.819	0	0
Postmitotic nuclear pore complex (NPC) reformation	R-HSA-9615933	1.723760e-01	0.764	0	0
Caspase activation via extrinsic apoptotic signalling pathway	R-HSA-5357769	1.723760e-01	0.764	0	0
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	1.561713e-01	0.806	0	0
Cytosolic sensors of pathogen-associated DNA	R-HSA-1834949	1.671935e-01	0.777	0	0
Mitochondrial unfolded protein response (UPRmt)	R-HSA-9841251	1.926510e-01	0.715	0	0
Cargo recognition for clathrin-mediated endocytosis	R-HSA-8856825	1.634766e-01	0.787	0	0
PI3K/AKT Signaling in Cancer	R-HSA-2219528	1.708580e-01	0.767	0	0
Mitophagy	R-HSA-5205647	1.550070e-01	0.810	0	0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	R-HSA-446343	1.450705e-01	0.838	0	0
Tandem pore domain potassium channels	R-HSA-1296346	1.755075e-01	0.756	0	0
Depolymerization of the Nuclear Lamina	R-HSA-4419969	1.912275e-01	0.718	0	0
Signaling by NTRK2 (TRKB)	R-HSA-9006115	1.926510e-01	0.715	0	0
Heme signaling	R-HSA-9707616	2.016643e-01	0.695	0	0
Regulation of MITF-M-dependent genes involved in pigmentation	R-HSA-9824585	1.836218e-01	0.736	0	0
Intrinsic Pathway for Apoptosis	R-HSA-109606	1.915888e-01	0.718	0	0
Cytokine Signaling in Immune system	R-HSA-1280215	1.530140e-01	0.815	0	0
Transcriptional regulation of granulopoiesis	R-HSA-9616222	2.016643e-01	0.695	0	0
SARS-CoV-2-host interactions	R-HSA-9705683	1.366532e-01	0.864	0	0
Nef and signal transduction	R-HSA-164944	1.924055e-01	0.716	0	0
Sensory processing of sound by outer hair cells of the cochlea	R-HSA-9662361	1.915888e-01	0.718	0	0
SARS-CoV-1-host interactions	R-HSA-9692914	1.415085e-01	0.849	0	0
Regulation of CDH11 gene transcription	R-HSA-9762293	1.440442e-01	0.842	0	0
Zygotic genome activation (ZGA)	R-HSA-9819196	1.498362e-01	0.824	0	0
Interleukin-4 and Interleukin-13 signaling	R-HSA-6785807	1.867054e-01	0.729	0	0
Assembly Of The HIV Virion	R-HSA-175474	1.707631e-01	0.768	0	0
Diseases of Mismatch Repair (MMR)	R-HSA-5423599	2.042585e-01	0.690	0	0
MET interacts with TNS proteins	R-HSA-8875513	2.042585e-01	0.690	0	0
FasL/ CD95L signaling	R-HSA-75157	2.042585e-01	0.690	0	0
Regulation of MITF-M dependent genes involved in metabolism	R-HSA-9854907	2.042585e-01	0.690	0	0
Activation of BIM and translocation to mitochondria	R-HSA-111446	2.042585e-01	0.690	0	0
Regulation of CDH1 Function	R-HSA-9764561	2.064570e-01	0.685	0	0
PECAM1 interactions	R-HSA-210990	2.090428e-01	0.680	0	0
Presynaptic depolarization and calcium channel opening	R-HSA-112308	2.090428e-01	0.680	0	0
Integrin signaling	R-HSA-354192	2.108574e-01	0.676	0	0
FGFR1 mutant receptor activation	R-HSA-1839124	2.108574e-01	0.676	0	0
Negative regulation of FGFR1 signaling	R-HSA-5654726	2.108574e-01	0.676	0	0
Regulation of TP53 Activity through Acetylation	R-HSA-6804758	2.108574e-01	0.676	0	0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	R-HSA-3371497	2.108673e-01	0.676	0	0
Regulation of T cell activation by CD28 family	R-HSA-388841	2.111624e-01	0.675	0	0
Formation of RNA Pol II elongation complex	R-HSA-112382	2.113413e-01	0.675	0	0
SARS-CoV-1 activates/modulates innate immune responses	R-HSA-9692916	2.113413e-01	0.675	0	0
RUNX2 regulates osteoblast differentiation	R-HSA-8940973	2.138604e-01	0.670	0	0
PINK1-PRKN Mediated Mitophagy	R-HSA-5205685	2.138604e-01	0.670	0	0
DCC mediated attractive signaling	R-HSA-418885	2.153027e-01	0.667	0	0
RIP-mediated NFkB activation via ZBP1	R-HSA-1810476	2.153027e-01	0.667	0	0
Protein methylation	R-HSA-8876725	2.153027e-01	0.667	0	0
IRF3-mediated induction of type I IFN	R-HSA-3270619	2.153027e-01	0.667	0	0
Defective Mismatch Repair Associated With MLH1	R-HSA-5545483	2.842989e-01	0.546	0	0
Defective DNA double strand break response due to BRCA1 loss of function	R-HSA-9663199	2.842989e-01	0.546	0	0
Defective Mismatch Repair Associated With MSH3	R-HSA-5632927	2.842989e-01	0.546	0	0
Defective DNA double strand break response due to BARD1 loss of function	R-HSA-9699150	2.842989e-01	0.546	0	0
Defective Mismatch Repair Associated With MSH6	R-HSA-5632968	2.842989e-01	0.546	0	0
TICAM1 deficiency - HSE	R-HSA-5602566	2.842989e-01	0.546	0	0
Defective F8 binding to von Willebrand factor	R-HSA-9672393	2.842989e-01	0.546	0	0
Defective Mismatch Repair Associated With PMS2	R-HSA-5632987	2.842989e-01	0.546	0	0
Impaired BRCA2 translocation to the nucleus	R-HSA-9709275	2.842989e-01	0.546	0	0
Impaired BRCA2 binding to SEM1 (DSS1)	R-HSA-9763198	2.842989e-01	0.546	0	0
TWIK-related spinal cord K+ channel (TRESK)	R-HSA-1299344	2.842989e-01	0.546	0	0
MECP2 regulates transcription of genes involved in GABA signaling	R-HSA-9022927	2.654978e-01	0.576	0	0
TNFR1-mediated ceramide production	R-HSA-5626978	2.654978e-01	0.576	0	0
HCN channels	R-HSA-1296061	2.654978e-01	0.576	0	0
NADE modulates death signalling	R-HSA-205025	2.654978e-01	0.576	0	0
AKT-mediated inactivation of FOXO1A	R-HSA-211163	2.654978e-01	0.576	0	0
NFE2L2 regulating ER-stress associated genes	R-HSA-9818035	2.654978e-01	0.576	0	0
Drug-mediated inhibition of CDK4/CDK6 activity	R-HSA-9754119	2.654978e-01	0.576	0	0
PLCG1 events in ERBB2 signaling	R-HSA-1251932	2.654978e-01	0.576	0	0
TGFBR1 KD Mutants in Cancer	R-HSA-3656532	2.654978e-01	0.576	0	0
FGFR4 mutant receptor activation	R-HSA-1839128	3.945326e-01	0.404	0	0
ARL13B-mediated ciliary trafficking of INPP5E	R-HSA-5624958	3.945326e-01	0.404	0	0
TGFBR3 regulates FGF2 signaling	R-HSA-9839397	3.945326e-01	0.404	0	0
Defective Mismatch Repair Associated With MSH2	R-HSA-5632928	3.945326e-01	0.404	0	0
NFG and proNGF binds to p75NTR	R-HSA-205017	3.945326e-01	0.404	0	0
MyD88 deficiency (TLR5)	R-HSA-5602680	3.945326e-01	0.404	0	0
SMAD2/3 MH2 Domain Mutants in Cancer	R-HSA-3315487	3.945326e-01	0.404	0	0
Defective HK1 causes hexokinase deficiency (HK deficiency)	R-HSA-5619056	3.945326e-01	0.404	0	0
TRAF3 deficiency - HSE	R-HSA-5602571	3.945326e-01	0.404	0	0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)	R-HSA-5619054	3.945326e-01	0.404	0	0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	R-HSA-9630794	3.945326e-01	0.404	0	0
TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P	R-HSA-6791055	3.945326e-01	0.404	0	0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	R-HSA-9632700	3.945326e-01	0.404	0	0
Loss of Function of SMAD4 in Cancer	R-HSA-3304347	3.945326e-01	0.404	0	0
SMAD4 MH2 Domain Mutants in Cancer	R-HSA-3311021	3.945326e-01	0.404	0	0
Defective SLC6A2 causes orthostatic intolerance (OI)	R-HSA-5619109	3.945326e-01	0.404	0	0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1)	R-HSA-5619111	3.945326e-01	0.404	0	0
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome	R-HSA-5678420	3.945326e-01	0.404	0	0
Defective VWF binding to collagen type I	R-HSA-9845622	3.945326e-01	0.404	0	0
TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P	R-HSA-6791462	3.945326e-01	0.404	0	0
RUNX1 regulates estrogen receptor mediated transcription	R-HSA-8931987	2.354719e-01	0.628	0	0
SOS-mediated signalling	R-HSA-112412	2.354719e-01	0.628	0	0
SHOC2 M1731 mutant abolishes MRAS complex function	R-HSA-9726840	2.354719e-01	0.628	0	0
RUNX1 regulates transcription of genes involved in BCR signaling	R-HSA-8939245	3.267537e-01	0.486	0	0
PTK6 Down-Regulation	R-HSA-8849472	3.267537e-01	0.486	0	0
IRS activation	R-HSA-74713	3.267537e-01	0.486	0	0
NFE2L2 regulating inflammation associated genes	R-HSA-9818026	3.267537e-01	0.486	0	0
NOSIP mediated eNOS trafficking	R-HSA-203754	3.267537e-01	0.486	0	0
G2 Phase	R-HSA-68911	3.267537e-01	0.486	0	0
Enhanced binding of GP1BA variant to VWF multimer:collagen	R-HSA-9845620	3.267537e-01	0.486	0	0
Defective binding of VWF variant to GPIb:IX:V	R-HSA-9846298	3.267537e-01	0.486	0	0
SMAD2/3 Phosphorylation Motif Mutants in Cancer	R-HSA-3304356	3.267537e-01	0.486	0	0
Type I hemidesmosome assembly	R-HSA-446107	2.799888e-01	0.553	0	0
Regulation by c-FLIP	R-HSA-3371378	2.799888e-01	0.553	0	0
Dimerization of procaspase-8	R-HSA-69416	2.799888e-01	0.553	0	0
Signaling by MRAS-complex mutants	R-HSA-9660537	2.799888e-01	0.553	0	0
Formation of annular gap junctions	R-HSA-196025	2.799888e-01	0.553	0	0
Regulation of NPAS4 mRNA translation	R-HSA-9768778	2.799888e-01	0.553	0	0
Gain-of-function MRAS complexes activate RAF signaling	R-HSA-9726842	2.799888e-01	0.553	0	0
Condensation of Prometaphase Chromosomes	R-HSA-2514853	2.442016e-01	0.612	0	0
Reduction of cytosolic Ca++ levels	R-HSA-418359	2.442016e-01	0.612	0	0
APC/C:Cdc20 mediated degradation of Cyclin B	R-HSA-174048	2.168931e-01	0.664	0	0
Caspase activation via Death Receptors in the presence of ligand	R-HSA-140534	2.455225e-01	0.610	0	0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	R-HSA-1362300	2.455225e-01	0.610	0	0
RUNX3 regulates p14-ARF	R-HSA-8951936	2.805389e-01	0.552	0	0
SHC-related events triggered by IGF1R	R-HSA-2428933	2.805389e-01	0.552	0	0
HuR (ELAVL1) binds and stabilizes mRNA	R-HSA-450520	3.251732e-01	0.488	0	0
ARMS-mediated activation	R-HSA-170984	3.251732e-01	0.488	0	0
Lipophagy	R-HSA-9613354	3.251732e-01	0.488	0	0
Inactivation of CDC42 and RAC1	R-HSA-428543	3.251732e-01	0.488	0	0
Gap junction degradation	R-HSA-190873	3.251732e-01	0.488	0	0
CASP8 activity is inhibited	R-HSA-5218900	3.251732e-01	0.488	0	0
SMAC, XIAP-regulated apoptotic response	R-HSA-111469	3.865691e-01	0.413	0	0
Epithelial-Mesenchymal Transition (EMT) during gastrulation	R-HSA-9758919	3.865691e-01	0.413	0	0
Defects of platelet adhesion to exposed collagen	R-HSA-9823587	3.865691e-01	0.413	0	0
PTK6 Regulates Cell Cycle	R-HSA-8849470	3.865691e-01	0.413	0	0
Phosphorylation of Emi1	R-HSA-176417	3.865691e-01	0.413	0	0
CDC6 association with the ORC:origin complex	R-HSA-68689	3.865691e-01	0.413	0	0
Loss-of-function mutations in DBT cause MSUD2	R-HSA-9865113	3.865691e-01	0.413	0	0
Loss-of-function mutations in DLD cause MSUD3/DLDD	R-HSA-9907570	3.865691e-01	0.413	0	0
Prefoldin mediated transfer of substrate to CCT/TriC	R-HSA-389957	2.160592e-01	0.665	0	0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex	R-HSA-9931521	2.767538e-01	0.558	0	0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	R-HSA-8877330	3.176268e-01	0.498	0	0
Formation of axial mesoderm	R-HSA-9796292	3.176268e-01	0.498	0	0
Signaling by ERBB2 TMD/JMD mutants	R-HSA-9665686	2.401833e-01	0.619	0	0
PD-L1(CD274) glycosylation and translocation to plasma membrane	R-HSA-9931295	2.712808e-01	0.567	0	0
MECP2 regulates transcription of neuronal ligands	R-HSA-9022702	3.703435e-01	0.431	0	0
Signaling by Erythropoietin	R-HSA-9006335	2.359088e-01	0.627	0	0
Signaling by ERBB2 KD Mutants	R-HSA-9664565	2.359088e-01	0.627	0	0
p130Cas linkage to MAPK signaling for integrins	R-HSA-372708	3.087241e-01	0.510	0	0
NFE2L2 regulating anti-oxidant/detoxification enzymes	R-HSA-9818027	2.312064e-01	0.636	0	0
DAP12 signaling	R-HSA-2424491	2.586949e-01	0.587	0	0
Gap-filling DNA repair synthesis and ligation in GG-NER	R-HSA-5696397	2.996277e-01	0.523	0	0
Signaling by FGFR4 in disease	R-HSA-5655291	3.550650e-01	0.450	0	0
Regulation of CDH1 mRNA translation by microRNAs	R-HSA-9764562	3.550650e-01	0.450	0	0
cGMP effects	R-HSA-418457	3.550650e-01	0.450	0	0
TAK1-dependent IKK and NF-kappa-B activation	R-HSA-445989	2.162986e-01	0.665	0	0
Formation of HIV-1 elongation complex containing HIV-1 Tat	R-HSA-167200	2.458495e-01	0.609	0	0
SCF-beta-TrCP mediated degradation of Emi1	R-HSA-174113	2.738642e-01	0.562	0	0
ChREBP activates metabolic gene expression	R-HSA-163765	4.149226e-01	0.382	0	0
RUNX2 regulates genes involved in cell migration	R-HSA-8941332	4.149226e-01	0.382	0	0
Regulation of CDH11 mRNA translation by microRNAs	R-HSA-9759811	4.149226e-01	0.382	0	0
Activated NTRK3 signals through RAS	R-HSA-9034864	4.149226e-01	0.382	0	0
RNA Polymerase II Transcription Elongation	R-HSA-75955	2.275689e-01	0.643	0	0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	R-HSA-174178	2.275689e-01	0.643	0	0
HIV Transcription Elongation	R-HSA-167169	2.659717e-01	0.575	0	0
Regulation of RUNX3 expression and activity	R-HSA-8941858	2.659717e-01	0.575	0	0
Tat-mediated elongation of the HIV-1 transcript	R-HSA-167246	2.659717e-01	0.575	0	0
Formation of HIV elongation complex in the absence of HIV Tat	R-HSA-167152	2.659717e-01	0.575	0	0
EPHA-mediated growth cone collapse	R-HSA-3928663	3.168402e-01	0.499	0	0
Interaction between L1 and Ankyrins	R-HSA-445095	3.168402e-01	0.499	0	0
Tat-mediated HIV elongation arrest and recovery	R-HSA-167243	3.168402e-01	0.499	0	0
Pausing and recovery of Tat-mediated HIV elongation	R-HSA-167238	3.168402e-01	0.499	0	0
Cristae formation	R-HSA-8949613	3.168402e-01	0.499	0	0
SCF(Skp2)-mediated degradation of p27/p21	R-HSA-187577	2.584231e-01	0.588	0	0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	R-HSA-450385	3.924874e-01	0.406	0	0
VEGFR2 mediated vascular permeability	R-HSA-5218920	2.865908e-01	0.543	0	0
Interleukin receptor SHC signaling	R-HSA-912526	3.576878e-01	0.446	0	0
HIV elongation arrest and recovery	R-HSA-167287	3.433535e-01	0.464	0	0
Pausing and recovery of HIV elongation	R-HSA-167290	3.433535e-01	0.464	0	0
Degradation of AXIN	R-HSA-4641257	3.185658e-01	0.497	0	0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	R-HSA-9762114	3.185658e-01	0.497	0	0
Ribosomal scanning and start codon recognition	R-HSA-72702	2.790208e-01	0.554	0	0
L13a-mediated translational silencing of Ceruloplasmin expression	R-HSA-156827	2.163572e-01	0.665	0	0
Developmental Lineages of the Mammary Gland	R-HSA-9924644	2.704603e-01	0.568	0	0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells	R-HSA-9927418	3.290300e-01	0.483	0	0
Formation of tubulin folding intermediates by CCT/TriC	R-HSA-389960	3.870386e-01	0.412	0	0
Regulation of PD-L1(CD274) translation	R-HSA-9909620	4.064848e-01	0.391	0	0
Co-inhibition by CTLA4	R-HSA-389513	4.064848e-01	0.391	0	0
GRB2:SOS provides linkage to MAPK signaling for Integrins	R-HSA-354194	4.295668e-01	0.367	0	0
Aberrant regulation of mitotic exit in cancer due to RB1 defects	R-HSA-9687136	4.295668e-01	0.367	0	0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	R-HSA-975956	2.543199e-01	0.595	0	0
Global Genome Nucleotide Excision Repair (GG-NER)	R-HSA-5696399	2.842053e-01	0.546	0	0
GSK3B-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929356	3.646036e-01	0.438	0	0
Ubiquitin-dependent degradation of Cyclin D	R-HSA-75815	3.799133e-01	0.420	0	0
SARS-CoV-1 modulates host translation machinery	R-HSA-9735869	3.799133e-01	0.420	0	0
Downstream signaling of activated FGFR4	R-HSA-5654716	3.969925e-01	0.401	0	0
GTP hydrolysis and joining of the 60S ribosomal subunit	R-HSA-72706	2.840997e-01	0.547	0	0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	R-HSA-8854050	4.048531e-01	0.393	0	0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	R-HSA-389958	4.238563e-01	0.373	0	0
Regulation of activated PAK-2p34 by proteasome mediated degradation	R-HSA-211733	4.238563e-01	0.373	0	0
Formation of a pool of free 40S subunits	R-HSA-72689	3.247103e-01	0.489	0	0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176814	3.852672e-01	0.414	0	0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	4.112723e-01	0.386	0	0
Autodegradation of Cdh1 by Cdh1:APC/C	R-HSA-174084	4.166485e-01	0.380	0	0
SRP-dependent cotranslational protein targeting to membrane	R-HSA-1799339	3.476101e-01	0.459	0	0
E3 ubiquitin ligases ubiquitinate target proteins	R-HSA-8866654	4.212412e-01	0.375	0	0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	R-HSA-174184	4.212412e-01	0.375	0	0
Developmental Lineage of Pancreatic Ductal Cells	R-HSA-9925563	4.134211e-01	0.384	0	0
Dual incision in TC-NER	R-HSA-6782135	4.252273e-01	0.371	0	0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	R-HSA-9954716	3.964909e-01	0.402	0	0
COPI-mediated anterograde transport	R-HSA-6807878	4.278241e-01	0.369	0	0
Nonsense-Mediated Decay (NMD)	R-HSA-927802	4.194549e-01	0.377	0	0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	R-HSA-975957	4.194549e-01	0.377	0	0
mRNA Splicing - Major Pathway	R-HSA-72163	4.305533e-01	0.366	0	0
FOXO-mediated transcription	R-HSA-9614085	3.010744e-01	0.521	0	0
APC/C-mediated degradation of cell cycle proteins	R-HSA-174143	2.550116e-01	0.593	0	0
Regulation of mitotic cell cycle	R-HSA-453276	2.550116e-01	0.593	0	0
Co-inhibition by PD-1	R-HSA-389948	3.683366e-01	0.434	0	0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	R-HSA-9841922	2.543231e-01	0.595	0	0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes	R-HSA-9851695	2.543231e-01	0.595	0	0
Mismatch Repair	R-HSA-5358508	3.411684e-01	0.467	0	0
IGF1R signaling cascade	R-HSA-2428924	2.312965e-01	0.636	0	0
Recycling pathway of L1	R-HSA-437239	2.162986e-01	0.665	0	0
Regulation of APC/C activators between G1/S and early anaphase	R-HSA-176408	2.876071e-01	0.541	0	0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	R-HSA-9818564	2.543231e-01	0.595	0	0
DNA Damage Bypass	R-HSA-73893	2.512008e-01	0.600	0	0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	R-HSA-5358565	3.087241e-01	0.510	0	0
Prolonged ERK activation events	R-HSA-169893	2.455225e-01	0.610	0	0
Microbial modulation of RIPK1-mediated regulated necrosis	R-HSA-9686347	2.354719e-01	0.628	0	0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	R-HSA-5358606	3.087241e-01	0.510	0	0
Eukaryotic Translation Elongation	R-HSA-156842	2.679122e-01	0.572	0	0
Translesion Synthesis by POLH	R-HSA-110320	2.168931e-01	0.664	0	0
Platelet calcium homeostasis	R-HSA-418360	3.701155e-01	0.432	0	0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	R-HSA-399955	4.295668e-01	0.367	0	0
ER to Golgi Anterograde Transport	R-HSA-199977	4.193149e-01	0.377	0	0
Signaling by FGFR2	R-HSA-5654738	3.086262e-01	0.511	0	0
Translocation of SLC2A4 (GLUT4) to the plasma membrane	R-HSA-1445148	3.814547e-01	0.419	0	0
Signal attenuation	R-HSA-74749	3.703435e-01	0.431	0	0
TP53 Regulates Transcription of Death Receptors and Ligands	R-HSA-6803211	3.550650e-01	0.450	0	0
Disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	3.168402e-01	0.499	0	0
Degradation of DVL	R-HSA-4641258	3.185658e-01	0.497	0	0
Platelet Aggregation (Plug Formation)	R-HSA-76009	3.945841e-01	0.404	0	0
Frs2-mediated activation	R-HSA-170968	3.176268e-01	0.498	0	0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	2.467535e-01	0.608	0	0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	R-HSA-166058	2.382309e-01	0.623	0	0
Activation of RAC1 downstream of NMDARs	R-HSA-9619229	3.251732e-01	0.488	0	0
Recognition of DNA damage by PCNA-containing replication complex	R-HSA-110314	2.401833e-01	0.619	0	0
Apoptosis induced DNA fragmentation	R-HSA-140342	3.703435e-01	0.431	0	0
EGFR Transactivation by Gastrin	R-HSA-2179392	3.703435e-01	0.431	0	0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	R-HSA-72662	2.218234e-01	0.654	0	0
SPOP-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929491	2.865908e-01	0.543	0	0
Chromatin modifications during the maternal to zygotic transition (MZT)	R-HSA-9821002	4.112723e-01	0.386	0	0
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	2.330441e-01	0.633	0	0
DDX58/IFIH1-mediated induction of interferon-alpha/beta	R-HSA-168928	3.964909e-01	0.402	0	0
MTOR signalling	R-HSA-165159	2.212988e-01	0.655	0	0
Ion homeostasis	R-HSA-5578775	2.790208e-01	0.554	0	0
RNA Polymerase II Pre-transcription Events	R-HSA-674695	3.022833e-01	0.520	0	0
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	2.382309e-01	0.623	0	0
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	2.731732e-01	0.564	0	0
TRAF3-dependent IRF activation pathway	R-HSA-918233	2.767538e-01	0.558	0	0
Signalling to ERKs	R-HSA-187687	2.738642e-01	0.562	0	0
Activation of NOXA and translocation to mitochondria	R-HSA-111448	2.654978e-01	0.576	0	0
Formation of lateral plate mesoderm	R-HSA-9758920	3.865691e-01	0.413	0	0
PI3K/AKT activation	R-HSA-198203	3.703435e-01	0.431	0	0
Autodegradation of the E3 ubiquitin ligase COP1	R-HSA-349425	2.522365e-01	0.598	0	0
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	2.731732e-01	0.564	0	0
Neurotransmitter receptors and postsynaptic signal transmission	R-HSA-112314	3.823830e-01	0.418	0	0
Dectin-1 mediated noncanonical NF-kB signaling	R-HSA-5607761	3.945841e-01	0.404	0	0
Opioid Signalling	R-HSA-111885	2.221493e-01	0.653	0	0
Eukaryotic Translation Initiation	R-HSA-72613	3.412822e-01	0.467	0	0
CLEC7A (Dectin-1) signaling	R-HSA-5607764	2.603359e-01	0.584	0	0
Adrenoceptors	R-HSA-390696	2.799888e-01	0.553	0	0
Growth hormone receptor signaling	R-HSA-982772	3.576878e-01	0.446	0	0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	R-HSA-381676	3.290300e-01	0.483	0	0
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	3.086262e-01	0.511	0	0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	R-HSA-427389	3.879023e-01	0.411	0	0
ADORA2B mediated anti-inflammatory cytokines production	R-HSA-9660821	3.945841e-01	0.404	0	0
Lysosome Vesicle Biogenesis	R-HSA-432720	4.297807e-01	0.367	0	0
Orc1 removal from chromatin	R-HSA-68949	4.212412e-01	0.375	0	0
Formation of the dystrophin-glycoprotein complex (DGC)	R-HSA-9913351	4.238563e-01	0.373	0	0
Signaling by FLT3 fusion proteins	R-HSA-9703465	2.907137e-01	0.537	0	0
Cap-dependent Translation Initiation	R-HSA-72737	3.412822e-01	0.467	0	0
Repression of WNT target genes	R-HSA-4641265	2.805389e-01	0.552	0	0
NoRC negatively regulates rRNA expression	R-HSA-427413	2.550116e-01	0.593	0	0
Pre-NOTCH Transcription and Translation	R-HSA-1912408	3.197737e-01	0.495	0	0
Regulation of PTEN stability and activity	R-HSA-8948751	3.261686e-01	0.487	0	0
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	2.359088e-01	0.627	0	0
Gastrulation	R-HSA-9758941	3.717939e-01	0.430	0	0
Cilium Assembly	R-HSA-5617833	2.671040e-01	0.573	0	0
Post-transcriptional silencing by small RNAs	R-HSA-426496	3.267537e-01	0.486	0	0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	R-HSA-9634638	2.160592e-01	0.665	0	0
Acetylcholine Neurotransmitter Release Cycle	R-HSA-264642	2.712808e-01	0.567	0	0
Modulation of host responses by IFN-stimulated genes	R-HSA-9909505	3.087241e-01	0.510	0	0
Inactivation of CSF3 (G-CSF) signaling	R-HSA-9705462	2.996277e-01	0.523	0	0
NIK-->noncanonical NF-kB signaling	R-HSA-5676590	4.112723e-01	0.386	0	0
Retrograde transport at the Trans-Golgi-Network	R-HSA-6811440	3.175625e-01	0.498	0	0
Interleukin-6 family signaling	R-HSA-6783589	2.401833e-01	0.619	0	0
Negative regulation of FGFR2 signaling	R-HSA-5654727	2.522365e-01	0.598	0	0
Circadian clock	R-HSA-9909396	2.201729e-01	0.657	0	0
GPVI-mediated activation cascade	R-HSA-114604	4.297807e-01	0.367	0	0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes	R-HSA-9856532	3.738341e-01	0.427	0	0
Regulation of KIT signaling	R-HSA-1433559	3.550650e-01	0.450	0	0
Nuclear Envelope (NE) Reassembly	R-HSA-2995410	3.086262e-01	0.511	0	0
Signaling by CSF3 (G-CSF)	R-HSA-9674555	2.359088e-01	0.627	0	0
The NLRP3 inflammasome	R-HSA-844456	3.738341e-01	0.427	0	0
Regulation of CDH11 Expression and Function	R-HSA-9759475	2.359088e-01	0.627	0	0
Aryl hydrocarbon receptor signalling	R-HSA-8937144	3.865691e-01	0.413	0	0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	R-HSA-75035	3.176268e-01	0.498	1	1
SARS-CoV-2 targets host intracellular signalling and regulatory pathways	R-HSA-9755779	3.924874e-01	0.406	0	0
Vasopressin regulates renal water homeostasis via Aquaporins	R-HSA-432040	2.777354e-01	0.556	0	0
Vpu mediated degradation of CD4	R-HSA-180534	3.550626e-01	0.450	0	0
Glycogen synthesis	R-HSA-3322077	2.436396e-01	0.613	0	0
NOTCH3 Intracellular Domain Regulates Transcription	R-HSA-9013508	2.586949e-01	0.587	0	0
Senescence-Associated Secretory Phenotype (SASP)	R-HSA-2559582	2.550305e-01	0.593	0	0
M-decay: degradation of maternal mRNAs by maternally stored factors	R-HSA-9820841	2.865908e-01	0.543	0	0
Organelle biogenesis and maintenance	R-HSA-1852241	2.220508e-01	0.654	0	0
mRNA Editing	R-HSA-75072	3.251732e-01	0.488	0	0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	R-HSA-9933387	2.586949e-01	0.587	0	0
Platelet sensitization by LDL	R-HSA-432142	3.411684e-01	0.467	0	0
Signaling by MET	R-HSA-6806834	3.086262e-01	0.511	0	0
Regulation of Expression and Function of Type II Classical Cadherins	R-HSA-9764260	3.304065e-01	0.481	0	0
Maternal to zygotic transition (MZT)	R-HSA-9816359	2.852392e-01	0.545	0	0
Formation of editosomes by ADAR proteins	R-HSA-77042	2.842989e-01	0.546	0	0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects	R-HSA-9632693	3.945326e-01	0.404	0	0
Manipulation of host energy metabolism	R-HSA-9636667	3.945326e-01	0.404	0	0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects	R-HSA-9630750	3.945326e-01	0.404	0	0
Mitochondrial transcription initiation	R-HSA-163282	3.945326e-01	0.404	0	0
TRAIL signaling	R-HSA-75158	3.865691e-01	0.413	0	0
Formation of the Editosome	R-HSA-75094	3.865691e-01	0.413	0	0
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	R-HSA-2559584	3.176268e-01	0.498	0	0
Regulation of FZD by ubiquitination	R-HSA-4641263	3.087241e-01	0.510	0	0
Downstream signal transduction	R-HSA-186763	2.821127e-01	0.550	0	0
Viral Messenger RNA Synthesis	R-HSA-168325	2.705852e-01	0.568	0	0
Phase 4 - resting membrane potential	R-HSA-5576886	4.295668e-01	0.367	0	0
Negative regulation of NOTCH4 signaling	R-HSA-9604323	3.879023e-01	0.411	0	0
Influenza Viral RNA Transcription and Replication	R-HSA-168273	3.073333e-01	0.512	0	0
Signaling by NTRKs	R-HSA-166520	4.319257e-01	0.365	0	0
Signaling by ERBB4	R-HSA-1236394	2.193145e-01	0.659	0	0
Regulation of pyruvate metabolism	R-HSA-9861718	4.166485e-01	0.380	0	0
Other semaphorin interactions	R-HSA-416700	3.924874e-01	0.406	0	0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	R-HSA-9735871	3.924874e-01	0.406	0	0
Interleukin-2 family signaling	R-HSA-451927	3.879023e-01	0.411	0	0
STING mediated induction of host immune responses	R-HSA-1834941	3.738341e-01	0.427	0	0
Ion transport by P-type ATPases	R-HSA-936837	4.287325e-01	0.368	0	0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	R-HSA-2660825	3.865691e-01	0.413	0	0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	R-HSA-2660826	3.865691e-01	0.413	0	0
Glycogen storage diseases	R-HSA-3229121	3.087241e-01	0.510	0	0
Mitochondrial biogenesis	R-HSA-1592230	3.547664e-01	0.450	0	0
Displacement of DNA glycosylase by APEX1	R-HSA-110357	2.354719e-01	0.628	0	0
Nuclear events stimulated by ALK signaling in cancer	R-HSA-9725371	3.379537e-01	0.471	0	0
Signal transduction by L1	R-HSA-445144	4.064848e-01	0.391	0	0
Ion channel transport	R-HSA-983712	3.752768e-01	0.426	0	0
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	3.244861e-01	0.489	0	0
Breakdown of the nuclear lamina	R-HSA-352238	3.945326e-01	0.404	0	0
Formation of the anterior neural plate	R-HSA-9823739	3.924874e-01	0.406	0	0
Syndecan interactions	R-HSA-3000170	3.576878e-01	0.446	0	0
Synthesis of IP3 and IP4 in the cytosol	R-HSA-1855204	3.304065e-01	0.481	0	0
Regulation of gene expression in beta cells	R-HSA-210745	3.701155e-01	0.432	0	0
Formation of the ternary complex, and subsequently, the 43S complex	R-HSA-72695	4.166485e-01	0.380	0	0
Gene Silencing by RNA	R-HSA-211000	3.476101e-01	0.459	0	0
Stimuli-sensing channels	R-HSA-2672351	2.163572e-01	0.665	0	0
PKR-mediated signaling	R-HSA-9833482	2.271025e-01	0.644	0	0
Interleukin-7 signaling	R-HSA-1266695	4.163754e-01	0.381	0	0
Nectin/Necl trans heterodimerization	R-HSA-420597	3.267537e-01	0.486	0	0
Regulation of BACH1 activity	R-HSA-9708530	2.455225e-01	0.610	0	0
Sodium-coupled phosphate cotransporters	R-HSA-427652	3.865691e-01	0.413	0	0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	R-HSA-110328	3.799133e-01	0.420	0	0
Influenza Infection	R-HSA-168255	3.938648e-01	0.405	0	0
SARS-CoV-1 Infection	R-HSA-9678108	2.876903e-01	0.541	0	0
SLC15A4:TASL-dependent IRF5 activation	R-HSA-9860276	3.865691e-01	0.413	0	0
BMAL1:CLOCK,NPAS2 activates circadian expression	R-HSA-1368108	3.799133e-01	0.420	0	0
Interleukin-37 signaling	R-HSA-9008059	3.969925e-01	0.401	0	0
tRNA processing in the nucleus	R-HSA-6784531	3.904369e-01	0.408	0	0
Caspase activation via Dependence Receptors in the absence of ligand	R-HSA-418889	3.251732e-01	0.488	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9694676	3.284916e-01	0.483	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9679504	3.411684e-01	0.467	0	0
Degradation of CRY and PER proteins	R-HSA-9932298	4.346307e-01	0.362	0	0
MHC class II antigen presentation	R-HSA-2132295	4.374684e-01	0.359	0	0
Signaling by NTRK1 (TRKA)	R-HSA-187037	4.390484e-01	0.357	0	0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	R-HSA-179419	4.421871e-01	0.354	0	0
Neurofascin interactions	R-HSA-447043	4.439350e-01	0.353	0	0
PTK6 promotes HIF1A stabilization	R-HSA-8857538	4.439350e-01	0.353	0	0
RUNX3 regulates YAP1-mediated transcription	R-HSA-8951671	4.439350e-01	0.353	0	0
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	R-HSA-629587	4.439350e-01	0.353	0	0
Branched-chain ketoacid dehydrogenase kinase deficiency	R-HSA-9912481	4.439350e-01	0.353	0	0
H139Hfs13* PPM1K causes a mild variant of MSUD	R-HSA-9912529	4.439350e-01	0.353	0	0
E2F-enabled inhibition of pre-replication complex formation	R-HSA-113507	4.439350e-01	0.353	0	0
Activation of NIMA Kinases NEK9, NEK6, NEK7	R-HSA-2980767	4.439350e-01	0.353	0	0
G2/M DNA replication checkpoint	R-HSA-69478	4.439350e-01	0.353	0	0
CREB3 factors activate genes	R-HSA-8874211	4.439350e-01	0.353	0	0
Deadenylation-dependent mRNA decay	R-HSA-429914	4.452180e-01	0.351	0	0
Adrenaline,noradrenaline inhibits insulin secretion	R-HSA-400042	4.455407e-01	0.351	0	0
Synthesis of PIPs at the Golgi membrane	R-HSA-1660514	4.455407e-01	0.351	0	0
Glutamate Neurotransmitter Release Cycle	R-HSA-210500	4.455407e-01	0.351	0	0
Interferon Signaling	R-HSA-913531	4.464452e-01	0.350	0	0
Developmental Cell Lineages of the Integumentary System	R-HSA-9734779	4.469979e-01	0.350	0	0
Recognition and association of DNA glycosylase with site containing an affected purine	R-HSA-110330	4.505862e-01	0.346	0	0
Peptide chain elongation	R-HSA-156902	4.561074e-01	0.341	0	0
MITF-M-dependent gene expression	R-HSA-9856651	4.571921e-01	0.340	0	0
Assembly of the pre-replicative complex	R-HSA-68867	4.577285e-01	0.339	0	0
Activated NTRK2 signals through RAS	R-HSA-9026519	4.584360e-01	0.339	0	0
APOBEC3G mediated resistance to HIV-1 infection	R-HSA-180689	4.584360e-01	0.339	0	0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters	R-HSA-9931512	4.584360e-01	0.339	0	0
Sensing of DNA Double Strand Breaks	R-HSA-5693548	4.584360e-01	0.339	0	0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis	R-HSA-9623433	4.584360e-01	0.339	0	0
Signaling by FGFR	R-HSA-190236	4.592242e-01	0.338	0	0
Regulation of insulin secretion	R-HSA-422356	4.592242e-01	0.338	0	0
DNA Replication Pre-Initiation	R-HSA-69002	4.619012e-01	0.335	0	0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	R-HSA-2892247	4.660166e-01	0.332	0	0
Processing of Intronless Pre-mRNAs	R-HSA-77595	4.660166e-01	0.332	0	0
mRNA decay by 5' to 3' exoribonuclease	R-HSA-430039	4.660166e-01	0.332	0	0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	R-HSA-141405	4.660166e-01	0.332	0	0
Inactivation of APC/C via direct inhibition of the APC/C complex	R-HSA-141430	4.660166e-01	0.332	0	0
Antigen processing: Ub, ATP-independent proteasomal degradation	R-HSA-9912633	4.660166e-01	0.332	0	0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	R-HSA-975110	4.660166e-01	0.332	0	0
SHC-mediated cascade:FGFR4	R-HSA-5654719	4.708931e-01	0.327	0	0
Signaling by PDGFR in disease	R-HSA-9671555	4.708931e-01	0.327	0	0
Signaling by NTRK3 (TRKC)	R-HSA-9034015	4.708931e-01	0.327	0	0
Initiation of Nuclear Envelope (NE) Reformation	R-HSA-2995383	4.708931e-01	0.327	0	0
Cellular response to chemical stress	R-HSA-9711123	4.712207e-01	0.327	0	0
Platelet activation, signaling and aggregation	R-HSA-76002	4.717119e-01	0.326	0	0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	R-HSA-8866652	4.743894e-01	0.324	0	0
Packaging Of Telomere Ends	R-HSA-171306	4.743894e-01	0.324	0	0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	R-HSA-6803204	4.743894e-01	0.324	0	0
Activation of anterior HOX genes in hindbrain development during early embryogenesis	R-HSA-5617472	4.758647e-01	0.323	0	0
Activation of HOX genes during differentiation	R-HSA-5619507	4.758647e-01	0.323	0	0
G-protein beta:gamma signalling	R-HSA-397795	4.770691e-01	0.321	0	0
Hh mutants abrogate ligand secretion	R-HSA-5387390	4.809988e-01	0.318	0	0
Degradation of CDH1	R-HSA-9766229	4.825110e-01	0.316	0	0
APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176409	4.838204e-01	0.315	0	0
IRS-related events triggered by IGF1R	R-HSA-2428928	4.849718e-01	0.314	0	0
Aquaporin-mediated transport	R-HSA-445717	4.849718e-01	0.314	0	0
Switching of origins to a post-replicative state	R-HSA-69052	4.869202e-01	0.313	0	0
Glycogen storage disease type XV (GYG1)	R-HSA-3814836	4.877932e-01	0.312	0	0
Defective VWF cleavage by ADAMTS13 variant	R-HSA-9845621	4.877932e-01	0.312	0	0
Signaling by RAS GAP mutants	R-HSA-9753510	4.877932e-01	0.312	0	0
Defective F8 cleavage by thrombin	R-HSA-9672391	4.877932e-01	0.312	0	0
TGFBR2 Kinase Domain Mutants in Cancer	R-HSA-3645790	4.877932e-01	0.312	0	0
Mitotic Metaphase/Anaphase Transition	R-HSA-68881	4.877932e-01	0.312	0	0
Enhanced cleavage of VWF variant by ADAMTS13	R-HSA-9845619	4.877932e-01	0.312	0	0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3)	R-HSA-5619089	4.877932e-01	0.312	0	0
TWIK related potassium channel (TREK)	R-HSA-1299503	4.877932e-01	0.312	0	0
Potassium transport channels	R-HSA-1296067	4.877932e-01	0.312	0	0
HHAT G278V doesn't palmitoylate Hh-Np	R-HSA-5658034	4.877932e-01	0.312	0	0
Glycogen storage disease type 0 (muscle GYS1)	R-HSA-3828062	4.877932e-01	0.312	0	0
mRNA Editing: A to I Conversion	R-HSA-75064	4.877932e-01	0.312	0	0
Defective ABCC8 can cause hypo- and hyper-glycemias	R-HSA-5683177	4.877932e-01	0.312	0	0
C6 deamination of adenosine	R-HSA-75102	4.877932e-01	0.312	0	0
Loss of Function of TGFBR2 in Cancer	R-HSA-3642278	4.877932e-01	0.312	0	0
Diseases of cellular response to stress	R-HSA-9675132	4.877932e-01	0.312	0	0
Diseases of Cellular Senescence	R-HSA-9630747	4.877932e-01	0.312	0	0
Transcription from mitochondrial promoters	R-HSA-75944	4.877932e-01	0.312	0	0
DSCAM interactions	R-HSA-376172	4.877932e-01	0.312	0	0
Activation, myristolyation of BID and translocation to mitochondria	R-HSA-75108	4.877932e-01	0.312	0	0
Nucleotide Excision Repair	R-HSA-5696398	4.910669e-01	0.309	0	0
Chromosome Maintenance	R-HSA-73886	4.925859e-01	0.308	0	0
Integration of energy metabolism	R-HSA-163685	4.938816e-01	0.306	0	0
Beta-catenin independent WNT signaling	R-HSA-3858494	4.938816e-01	0.306	0	0
MECP2 regulates transcription factors	R-HSA-9022707	4.981872e-01	0.303	0	0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	R-HSA-2892245	4.981872e-01	0.303	0	0
Activated NTRK2 signals through CDK5	R-HSA-9032845	4.981872e-01	0.303	0	0
PTK6 Expression	R-HSA-8849473	4.981872e-01	0.303	0	0
Insulin effects increased synthesis of Xylulose-5-Phosphate	R-HSA-163754	4.981872e-01	0.303	0	0
Disinhibition of SNARE formation	R-HSA-114516	4.981872e-01	0.303	0	0
mRNA Editing: C to U Conversion	R-HSA-72200	4.981872e-01	0.303	0	0
Activated NTRK3 signals through PI3K	R-HSA-9603381	4.981872e-01	0.303	0	0
CHL1 interactions	R-HSA-447041	4.981872e-01	0.303	0	0
TGFBR3 regulates TGF-beta signaling	R-HSA-9839389	4.981872e-01	0.303	0	0
Uptake and function of diphtheria toxin	R-HSA-5336415	4.981872e-01	0.303	0	0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex	R-HSA-9931530	5.005055e-01	0.301	0	0
MET activates RAS signaling	R-HSA-8851805	5.005055e-01	0.301	0	0
PI3K events in ERBB2 signaling	R-HSA-1963642	5.015921e-01	0.300	0	0
Synthesis of PIPs at the late endosome membrane	R-HSA-1660517	5.015921e-01	0.300	0	0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	R-HSA-9670439	5.022806e-01	0.299	0	0
Signaling by KIT in disease	R-HSA-9669938	5.022806e-01	0.299	0	0
Formation of the HIV-1 Early Elongation Complex	R-HSA-167158	5.027897e-01	0.299	0	0
Formation of the Early Elongation Complex	R-HSA-113418	5.027897e-01	0.299	0	0
Inflammasomes	R-HSA-622312	5.027897e-01	0.299	0	0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane	R-HSA-9768727	5.032012e-01	0.298	0	0
DAP12 interactions	R-HSA-2172127	5.038621e-01	0.298	0	0
PI3K Cascade	R-HSA-109704	5.041426e-01	0.297	0	0
Transcription of the HIV genome	R-HSA-167172	5.048674e-01	0.297	0	0
Signaling by FGFR in disease	R-HSA-1226099	5.050817e-01	0.297	0	0
Non-integrin membrane-ECM interactions	R-HSA-3000171	5.230864e-01	0.281	0	0
IRS-mediated signalling	R-HSA-112399	5.247567e-01	0.280	0	0
TP53 Regulates Transcription of Cell Cycle Genes	R-HSA-6791312	5.247567e-01	0.280	0	0
Hedgehog ligand biogenesis	R-HSA-5358346	5.255154e-01	0.279	0	0
Defective CFTR causes cystic fibrosis	R-HSA-5678895	5.264220e-01	0.279	0	0
Asymmetric localization of PCP proteins	R-HSA-4608870	5.264220e-01	0.279	0	0
Inhibition of DNA recombination at telomere	R-HSA-9670095	5.275231e-01	0.278	0	0
Generation of second messenger molecules	R-HSA-202433	5.275231e-01	0.278	0	0
Signaling by NOTCH2	R-HSA-1980145	5.288877e-01	0.277	0	0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	R-HSA-6814122	5.288877e-01	0.277	0	0
NPAS4 regulates expression of target genes	R-HSA-9768919	5.288877e-01	0.277	0	0
Downstream signaling of activated FGFR3	R-HSA-5654708	5.306242e-01	0.275	0	0
DNA methylation	R-HSA-5334118	5.306242e-01	0.275	0	0
Toll-like Receptor Cascades	R-HSA-168898	5.310021e-01	0.275	0	0
G beta:gamma signalling through PI3Kgamma	R-HSA-392451	5.329139e-01	0.273	0	0
The role of Nef in HIV-1 replication and disease pathogenesis	R-HSA-164952	5.329139e-01	0.273	0	0
FOXO-mediated transcription of cell death genes	R-HSA-9614657	5.360890e-01	0.271	0	0
Trafficking of GluR2-containing AMPA receptors	R-HSA-416993	5.360890e-01	0.271	0	0
Tie2 Signaling	R-HSA-210993	5.360890e-01	0.271	0	0
Nephron development	R-HSA-9831926	5.360890e-01	0.271	0	0
Transmission across Chemical Synapses	R-HSA-112315	5.374140e-01	0.270	0	0
Adenylate cyclase activating pathway	R-HSA-170660	5.408403e-01	0.267	0	0
Acyl chain remodeling of DAG and TAG	R-HSA-1482883	5.408403e-01	0.267	0	0
Platelet Adhesion to exposed collagen	R-HSA-75892	5.408403e-01	0.267	0	0
Replication of the SARS-CoV-1 genome	R-HSA-9682706	5.408403e-01	0.267	0	0
COPII-mediated vesicle transport	R-HSA-204005	5.420462e-01	0.266	0	0
Insulin receptor signalling cascade	R-HSA-74751	5.433480e-01	0.265	0	0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	R-HSA-9029569	5.448422e-01	0.264	0	0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)	R-HSA-9931269	5.465768e-01	0.262	0	0
Transcriptional Regulation by NPAS4	R-HSA-9634815	5.465768e-01	0.262	0	0
Signaling by TGFBR3	R-HSA-9839373	5.486179e-01	0.261	0	0
RSK activation	R-HSA-444257	5.489240e-01	0.260	0	0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	R-HSA-77588	5.489240e-01	0.260	0	0
Formyl peptide receptors bind formyl peptides and many other ligands	R-HSA-444473	5.489240e-01	0.260	0	0
Nef mediated downregulation of MHC class I complex cell surface expression	R-HSA-164940	5.489240e-01	0.260	0	0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors	R-HSA-8866904	5.489240e-01	0.260	0	0
Interleukin-18 signaling	R-HSA-9012546	5.489240e-01	0.260	0	0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence	R-HSA-9825895	5.489240e-01	0.260	0	0
Hh mutants are degraded by ERAD	R-HSA-5362768	5.510601e-01	0.259	0	0
mRNA Splicing	R-HSA-72172	5.524678e-01	0.258	0	0
SARS-CoV-2 Infection	R-HSA-9694516	5.539878e-01	0.256	0	0
Regulation of Apoptosis	R-HSA-169911	5.540438e-01	0.256	0	0
Interleukin-1 family signaling	R-HSA-446652	5.577462e-01	0.254	0	0
Activation of the pre-replicative complex	R-HSA-68962	5.577892e-01	0.254	0	0
GABA synthesis, release, reuptake and degradation	R-HSA-888590	5.577892e-01	0.254	0	0
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	5.626640e-01	0.250	0	0
Thromboxane signalling through TP receptor	R-HSA-428930	5.626640e-01	0.250	0	0
TRAF6 mediated NF-kB activation	R-HSA-933542	5.626640e-01	0.250	0	0
Signaling by FLT3 ITD and TKD mutants	R-HSA-9703648	5.626640e-01	0.250	0	0
Norepinephrine Neurotransmitter Release Cycle	R-HSA-181430	5.626640e-01	0.250	0	0
Axonal growth stimulation	R-HSA-209563	5.666933e-01	0.247	0	0
TFAP2 (AP-2) family regulates transcription of other transcription factors	R-HSA-8866906	5.666933e-01	0.247	0	0
The IPAF inflammasome	R-HSA-844623	5.666933e-01	0.247	0	0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins	R-HSA-9673766	5.666933e-01	0.247	0	0
IRAK4 deficiency (TLR5)	R-HSA-5603037	5.666933e-01	0.247	0	0
Invadopodia formation	R-HSA-8941237	5.666933e-01	0.247	0	0
Phenylketonuria	R-HSA-2160456	5.666933e-01	0.247	0	0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome	R-HSA-9944997	5.666933e-01	0.247	0	0
Defective GCLC causes HAGGSD	R-HSA-5578999	5.666933e-01	0.247	0	0
Loss of Function of KMT2D in Kabuki Syndrome	R-HSA-9944971	5.666933e-01	0.247	0	0
Defective CYP7B1 causes SPG5A and CBAS3	R-HSA-5579013	5.666933e-01	0.247	0	0
Defective HPRT1 disrupts guanine and hypoxanthine salvage	R-HSA-9734281	5.666933e-01	0.247	0	0
Defective CYP1B1 causes Glaucoma	R-HSA-5579000	5.666933e-01	0.247	0	0
Defective ABCC2 causes DJS	R-HSA-5679001	5.666933e-01	0.247	0	0
STAT6-mediated induction of chemokines	R-HSA-3249367	5.666933e-01	0.247	0	0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	R-HSA-5368598	5.666933e-01	0.247	0	0
Activation of BMF and translocation to mitochondria	R-HSA-139910	5.666933e-01	0.247	0	0
Intracellular oxygen transport	R-HSA-8981607	5.666933e-01	0.247	0	0
Histamine receptors	R-HSA-390650	5.666933e-01	0.247	0	0
Abortive elongation of HIV-1 transcript in the absence of Tat	R-HSA-167242	5.693416e-01	0.245	0	0
Specification of the neural plate border	R-HSA-9834899	5.693416e-01	0.245	0	0
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	5.693416e-01	0.245	0	0
E2F mediated regulation of DNA replication	R-HSA-113510	5.693416e-01	0.245	0	0
Other interleukin signaling	R-HSA-449836	5.693416e-01	0.245	0	0
Signaling by Nuclear Receptors	R-HSA-9006931	5.701555e-01	0.244	0	0
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	5.703943e-01	0.244	0	0
APC/C:Cdc20 mediated degradation of Securin	R-HSA-174154	5.703943e-01	0.244	0	0
Intra-Golgi traffic	R-HSA-6811438	5.740989e-01	0.241	0	0
Cardiac conduction	R-HSA-5576891	5.744134e-01	0.241	0	0
PCP/CE pathway	R-HSA-4086400	5.758396e-01	0.240	0	0
Triglyceride catabolism	R-HSA-163560	5.785946e-01	0.238	0	0
CRMPs in Sema3A signaling	R-HSA-399956	5.792278e-01	0.237	0	0
ERBB2 Activates PTK6 Signaling	R-HSA-8847993	5.792278e-01	0.237	0	0
Prolactin receptor signaling	R-HSA-1170546	5.792278e-01	0.237	0	0
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	5.792278e-01	0.237	0	0
SARS-CoV-1 Genome Replication and Transcription	R-HSA-9679514	5.792278e-01	0.237	0	0
HDL assembly	R-HSA-8963896	5.792278e-01	0.237	0	0
MITF-M-regulated melanocyte development	R-HSA-9730414	5.838201e-01	0.234	0	0
RAB geranylgeranylation	R-HSA-8873719	5.840346e-01	0.234	0	0
Cargo concentration in the ER	R-HSA-5694530	5.841957e-01	0.233	0	0
Metabolism of RNA	R-HSA-8953854	5.854191e-01	0.233	0	0
HCMV Early Events	R-HSA-9609690	5.864955e-01	0.232	0	0
CDK-mediated phosphorylation and removal of Cdc6	R-HSA-69017	5.875764e-01	0.231	0	0
SARS-CoV-2 modulates host translation machinery	R-HSA-9754678	5.875764e-01	0.231	0	0
Tight junction interactions	R-HSA-420029	5.914234e-01	0.228	0	0
TGFBR3 expression	R-HSA-9839394	5.914234e-01	0.228	0	0
VEGFR2 mediated cell proliferation	R-HSA-5218921	5.914234e-01	0.228	0	0
Ca2+ pathway	R-HSA-4086398	5.958973e-01	0.225	0	0
Estrogen-stimulated signaling through PRKCZ	R-HSA-9634635	5.959412e-01	0.225	0	0
Interleukin-21 signaling	R-HSA-9020958	5.959412e-01	0.225	0	0
Regulated proteolysis of p75NTR	R-HSA-193692	5.959412e-01	0.225	0	0
MAPK1 (ERK2) activation	R-HSA-112411	5.959412e-01	0.225	0	0
Regulation of commissural axon pathfinding by SLIT and ROBO	R-HSA-428542	5.959412e-01	0.225	0	0
Unwinding of DNA	R-HSA-176974	5.959412e-01	0.225	0	0
WNT mediated activation of DVL	R-HSA-201688	5.959412e-01	0.225	0	0
Activation of the TFAP2 (AP-2) family of transcription factors	R-HSA-8866907	5.959412e-01	0.225	0	0
Activation of the AP-1 family of transcription factors	R-HSA-450341	5.959412e-01	0.225	0	0
Respiratory syncytial virus genome replication	R-HSA-9834752	5.959412e-01	0.225	0	0
Butyrophilin (BTN) family interactions	R-HSA-8851680	5.959412e-01	0.225	0	0
Cleavage of the damaged pyrimidine	R-HSA-110329	5.965830e-01	0.224	0	0
Depyrimidination	R-HSA-73928	5.965830e-01	0.224	0	0
Interleukin-1 signaling	R-HSA-9020702	5.985832e-01	0.223	0	0
Kidney development	R-HSA-9830369	5.992571e-01	0.222	0	0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide	R-HSA-9954709	6.009824e-01	0.221	0	0
PI-3K cascade:FGFR4	R-HSA-5654720	6.012208e-01	0.221	0	0
BBSome-mediated cargo-targeting to cilium	R-HSA-5620922	6.012208e-01	0.221	0	0
Creatine metabolism	R-HSA-71288	6.012208e-01	0.221	0	0
Voltage gated Potassium channels	R-HSA-1296072	6.024748e-01	0.220	0	0
Cleavage of the damaged purine	R-HSA-110331	6.024748e-01	0.220	0	0
NCAM1 interactions	R-HSA-419037	6.024748e-01	0.220	0	0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	R-HSA-9954714	6.036053e-01	0.219	0	0
COPI-independent Golgi-to-ER retrograde traffic	R-HSA-6811436	6.074310e-01	0.217	0	0
Pre-NOTCH Expression and Processing	R-HSA-1912422	6.084332e-01	0.216	0	0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells	R-HSA-9937080	6.097683e-01	0.215	0	0
Signaling by NOTCH4	R-HSA-9013694	6.132160e-01	0.212	0	0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	R-HSA-8948700	6.155233e-01	0.211	0	0
Erythropoietin activates RAS	R-HSA-9027284	6.155233e-01	0.211	0	0
Adenylate cyclase inhibitory pathway	R-HSA-170670	6.155233e-01	0.211	0	0
SHC1 events in EGFR signaling	R-HSA-180336	6.155233e-01	0.211	0	0
ERBB2 Regulates Cell Motility	R-HSA-6785631	6.155233e-01	0.211	0	0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	R-HSA-450513	6.155233e-01	0.211	0	0
Lysosphingolipid and LPA receptors	R-HSA-419408	6.155233e-01	0.211	0	0
p38MAPK events	R-HSA-171007	6.155233e-01	0.211	0	0
Activation of BAD and translocation to mitochondria	R-HSA-111447	6.155233e-01	0.211	0	0
Signaling by PDGFRA extracellular domain mutants	R-HSA-9673770	6.155233e-01	0.211	0	0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	R-HSA-9673767	6.155233e-01	0.211	0	0
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	6.161118e-01	0.210	0	0
Potassium Channels	R-HSA-1296071	6.161118e-01	0.210	0	0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	R-HSA-9931510	6.191055e-01	0.208	0	0
Myogenesis	R-HSA-525793	6.191055e-01	0.208	0	0
Mitochondrial protein import	R-HSA-1268020	6.216778e-01	0.206	0	0
NCAM signaling for neurite out-growth	R-HSA-375165	6.216778e-01	0.206	0	0
Depurination	R-HSA-73927	6.256289e-01	0.204	0	0
Gap-filling DNA repair synthesis and ligation in TC-NER	R-HSA-6782210	6.268069e-01	0.203	0	0
Negative regulation of the PI3K/AKT network	R-HSA-199418	6.282502e-01	0.202	0	0
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	6.299234e-01	0.201	0	0
Protein ubiquitination	R-HSA-8852135	6.301760e-01	0.201	0	0
SHC-mediated cascade:FGFR3	R-HSA-5654704	6.316303e-01	0.200	0	0
Signalling to RAS	R-HSA-167044	6.316303e-01	0.200	0	0
ERK/MAPK targets	R-HSA-198753	6.316303e-01	0.200	0	0
Basigin interactions	R-HSA-210991	6.316303e-01	0.200	0	0
Regulation of MITF-M-dependent genes involved in apoptosis	R-HSA-9824594	6.316303e-01	0.200	0	0
Prevention of phagosomal-lysosomal fusion	R-HSA-9636383	6.316303e-01	0.200	0	0
ATP sensitive Potassium channels	R-HSA-1296025	6.334435e-01	0.198	0	0
betaKlotho-mediated ligand binding	R-HSA-1307965	6.334435e-01	0.198	0	0
Signaling by MAP2K mutants	R-HSA-9652169	6.334435e-01	0.198	0	0
Defective LFNG causes SCDO3	R-HSA-5083630	6.334435e-01	0.198	0	0
FBXW7 Mutants and NOTCH1 in Cancer	R-HSA-2644605	6.334435e-01	0.198	0	0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	R-HSA-69200	6.334435e-01	0.198	0	0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling	R-HSA-2644607	6.334435e-01	0.198	0	0
SARS-CoV-1-mediated effects on programmed cell death	R-HSA-9692913	6.334435e-01	0.198	0	0
Transmission across Electrical Synapses	R-HSA-112307	6.334435e-01	0.198	0	0
Electric Transmission Across Gap Junctions	R-HSA-112303	6.334435e-01	0.198	0	0
Inhibition of TSC complex formation by PKB	R-HSA-165181	6.334435e-01	0.198	0	0
MDK and PTN in ALK signaling	R-HSA-9851151	6.334435e-01	0.198	0	0
FLT3 signaling through SRC family kinases	R-HSA-9706374	6.334435e-01	0.198	0	0
Dopamine receptors	R-HSA-390651	6.334435e-01	0.198	0	0
Regulation of HMOX1 expression and activity	R-HSA-9707587	6.334435e-01	0.198	0	0
SARS-CoV-2 targets PDZ proteins in cell-cell junction	R-HSA-9705677	6.334435e-01	0.198	0	0
Interleukin-38 signaling	R-HSA-9007892	6.334435e-01	0.198	0	0
Assembly of the ORC complex at the origin of replication	R-HSA-68616	6.344453e-01	0.198	0	0
Chaperonin-mediated protein folding	R-HSA-390466	6.381062e-01	0.195	0	0
Binding and entry of HIV virion	R-HSA-173107	6.391807e-01	0.194	0	0
Erythropoietin activates Phospholipase C gamma (PLCG)	R-HSA-9027277	6.391807e-01	0.194	0	0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	R-HSA-5140745	6.391807e-01	0.194	0	0
Interleukin-27 signaling	R-HSA-9020956	6.391807e-01	0.194	0	0
Receptor Mediated Mitophagy	R-HSA-8934903	6.391807e-01	0.194	0	0
Regulation of the apoptosome activity	R-HSA-9627069	6.391807e-01	0.194	0	0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	R-HSA-428359	6.391807e-01	0.194	0	0
Formation of apoptosome	R-HSA-111458	6.391807e-01	0.194	0	0
Assembly and release of respiratory syncytial virus (RSV) virions	R-HSA-9820962	6.391807e-01	0.194	0	0
Signaling by Leptin	R-HSA-2586552	6.391807e-01	0.194	0	0
Proteasome assembly	R-HSA-9907900	6.396961e-01	0.194	0	0
Activation of gene expression by SREBF (SREBP)	R-HSA-2426168	6.398403e-01	0.194	0	0
RNA Polymerase I Promoter Opening	R-HSA-73728	6.456431e-01	0.190	0	0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	R-HSA-9725554	6.480110e-01	0.188	0	0
Phosphorylation of the APC/C	R-HSA-176412	6.496399e-01	0.187	0	0
WNT5A-dependent internalization of FZD4	R-HSA-5099900	6.496399e-01	0.187	0	0
Differentiation of T cells	R-HSA-9945266	6.496399e-01	0.187	0	0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)	R-HSA-9942503	6.496399e-01	0.187	0	0
Receptor-type tyrosine-protein phosphatases	R-HSA-388844	6.496399e-01	0.187	0	0
Activation of SMO	R-HSA-5635838	6.496399e-01	0.187	0	0
Regulation of endogenous retroelements by KRAB-ZFP proteins	R-HSA-9843940	6.518261e-01	0.186	0	0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	R-HSA-1234176	6.523940e-01	0.185	0	0
Effects of PIP2 hydrolysis	R-HSA-114508	6.581775e-01	0.182	0	0
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	6.583888e-01	0.182	0	0
NR1H2 and NR1H3-mediated signaling	R-HSA-9024446	6.629342e-01	0.179	0	0
Early SARS-CoV-2 Infection Events	R-HSA-9772572	6.640039e-01	0.178	0	0
ER-Phagosome pathway	R-HSA-1236974	6.683973e-01	0.175	0	0
Diseases of Immune System	R-HSA-5260271	6.695838e-01	0.174	0	0
Diseases associated with the TLR signaling cascade	R-HSA-5602358	6.695838e-01	0.174	0	0
Glycogen metabolism	R-HSA-8982491	6.695838e-01	0.174	0	0
Pyroptosis	R-HSA-5620971	6.709870e-01	0.173	0	0
mRNA 3'-end processing	R-HSA-72187	6.714377e-01	0.173	0	0
RNA Polymerase I Promoter Escape	R-HSA-73772	6.714377e-01	0.173	0	0
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	6.776527e-01	0.169	0	0
FGFRL1 modulation of FGFR1 signaling	R-HSA-5658623	6.786906e-01	0.168	0	0
Formation of the posterior neural plate	R-HSA-9832991	6.786906e-01	0.168	0	0
Bicarbonate transporters	R-HSA-425381	6.786906e-01	0.168	0	0
Dissolution of Fibrin Clot	R-HSA-75205	6.786906e-01	0.168	0	0
Transport of RCbl within the body	R-HSA-9758890	6.786906e-01	0.168	0	0
Synthesis of PI	R-HSA-1483226	6.786906e-01	0.168	0	0
Interleukin-2 signaling	R-HSA-9020558	6.786906e-01	0.168	0	0
Condensation of Prophase Chromosomes	R-HSA-2299718	6.800876e-01	0.167	0	0
Formation of TC-NER Pre-Incision Complex	R-HSA-6781823	6.800876e-01	0.167	0	0
Signal amplification	R-HSA-392518	6.809277e-01	0.167	0	0
GRB2 events in ERBB2 signaling	R-HSA-1963640	6.815397e-01	0.167	0	0
Phase 2 - plateau phase	R-HSA-5576893	6.815397e-01	0.167	0	0
STAT5 activation downstream of FLT3 ITD mutants	R-HSA-9702518	6.815397e-01	0.167	0	0
Response to metal ions	R-HSA-5660526	6.815397e-01	0.167	0	0
Platelet homeostasis	R-HSA-418346	6.831511e-01	0.165	0	0
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	6.846935e-01	0.165	0	0
Extra-nuclear estrogen signaling	R-HSA-9009391	6.874732e-01	0.163	0	0
Selenocysteine synthesis	R-HSA-2408557	6.874732e-01	0.163	0	0
FRS-mediated FGFR4 signaling	R-HSA-5654712	6.878021e-01	0.163	0	0
FGFR2 alternative splicing	R-HSA-6803529	6.878021e-01	0.163	0	0
Regulation of IFNA/IFNB signaling	R-HSA-912694	6.878021e-01	0.163	0	0
Activation of AMPA receptors	R-HSA-399710	6.899141e-01	0.161	0	0
RUNX1 regulates transcription of genes involved in interleukin signaling	R-HSA-8939247	6.899141e-01	0.161	0	0
NFE2L2 regulating TCA cycle genes	R-HSA-9818025	6.899141e-01	0.161	0	0
SMAC (DIABLO) binds to IAPs	R-HSA-111463	6.899141e-01	0.161	0	0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	R-HSA-111464	6.899141e-01	0.161	0	0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	R-HSA-9673768	6.899141e-01	0.161	0	0
Defective F9 activation	R-HSA-9673221	6.899141e-01	0.161	0	0
IRF3 mediated activation of type 1 IFN	R-HSA-1606341	6.899141e-01	0.161	0	0
Activation of AKT2	R-HSA-165158	6.899141e-01	0.161	0	0
Reelin signalling pathway	R-HSA-8866376	6.899141e-01	0.161	0	0
Suppression of autophagy	R-HSA-9636569	6.899141e-01	0.161	0	0
Muscarinic acetylcholine receptors	R-HSA-390648	6.899141e-01	0.161	0	0
Inositol transporters	R-HSA-429593	6.899141e-01	0.161	0	0
Biosynthesis of DPAn-3-derived 13-series resolvins	R-HSA-9026403	6.899141e-01	0.161	0	0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK	R-HSA-9931529	6.899141e-01	0.161	0	0
NrCAM interactions	R-HSA-447038	6.899141e-01	0.161	0	0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	R-HSA-3134963	6.899141e-01	0.161	0	0
Toxicity of botulinum toxin type C (botC)	R-HSA-5250971	6.899141e-01	0.161	0	0
Zinc efflux and compartmentalization by the SLC30 family	R-HSA-435368	6.899141e-01	0.161	0	0
Resolution of Abasic Sites (AP sites)	R-HSA-73933	6.903187e-01	0.161	0	0
Eukaryotic Translation Termination	R-HSA-72764	6.921536e-01	0.160	0	0
Nitric oxide stimulates guanylate cyclase	R-HSA-392154	6.951046e-01	0.158	0	0
Regulation of expression of SLITs and ROBOs	R-HSA-9010553	7.022216e-01	0.154	0	0
Downstream signaling of activated FGFR1	R-HSA-5654687	7.026701e-01	0.153	0	0
Downstream signaling of activated FGFR2	R-HSA-5654696	7.026701e-01	0.153	0	0
Regulation of PD-L1(CD274) Post-translational modification	R-HSA-9909615	7.028041e-01	0.153	0	0
Base-Excision Repair, AP Site Formation	R-HSA-73929	7.075999e-01	0.150	0	0
Removal of the Flap Intermediate from the C-strand	R-HSA-174437	7.112244e-01	0.148	0	0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	R-HSA-176407	7.112244e-01	0.148	0	0
Elevation of cytosolic Ca2+ levels	R-HSA-139853	7.112244e-01	0.148	0	0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	R-HSA-164938	7.112244e-01	0.148	0	0
Uptake and function of anthrax toxins	R-HSA-5210891	7.112244e-01	0.148	0	0
Regulation of NPAS4 gene expression	R-HSA-9768759	7.112244e-01	0.148	0	0
Replication of the SARS-CoV-2 genome	R-HSA-9694686	7.112244e-01	0.148	0	0
Synthesis of pyrophosphates in the cytosol	R-HSA-1855167	7.135081e-01	0.147	0	0
Formation of the ureteric bud	R-HSA-9830674	7.135081e-01	0.147	0	0
Regulation of gene expression by Hypoxia-inducible Factor	R-HSA-1234158	7.145938e-01	0.146	0	0
Presynaptic nicotinic acetylcholine receptors	R-HSA-622323	7.145938e-01	0.146	0	0
ERKs are inactivated	R-HSA-202670	7.145938e-01	0.146	0	0
Inhibition of replication initiation of damaged DNA by RB1/E2F1	R-HSA-113501	7.145938e-01	0.146	0	0
POLB-Dependent Long Patch Base Excision Repair	R-HSA-110362	7.145938e-01	0.146	0	0
Sodium/Calcium exchangers	R-HSA-425561	7.145938e-01	0.146	0	0
Cytochrome c-mediated apoptotic response	R-HSA-111461	7.145938e-01	0.146	0	0
Integration of provirus	R-HSA-162592	7.145938e-01	0.146	0	0
ATF6 (ATF6-alpha) activates chaperone genes	R-HSA-381183	7.145938e-01	0.146	0	0
RNA Polymerase II Transcription Termination	R-HSA-73856	7.155772e-01	0.145	0	0
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	7.179778e-01	0.144	0	0
PRC2 methylates histones and DNA	R-HSA-212300	7.233887e-01	0.141	0	0
Protein folding	R-HSA-391251	7.245553e-01	0.140	0	0
Response of EIF2AK4 (GCN2) to amino acid deficiency	R-HSA-9633012	7.264261e-01	0.139	0	0
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	R-HSA-6781827	7.304015e-01	0.136	0	0
TP53 Regulates Transcription of Cell Death Genes	R-HSA-5633008	7.304015e-01	0.136	0	0
SHC-mediated cascade:FGFR1	R-HSA-5654688	7.376253e-01	0.132	0	0
Plasma lipoprotein assembly	R-HSA-8963898	7.376253e-01	0.132	0	0
Plus-strand DNA synthesis	R-HSA-164525	7.376878e-01	0.132	0	0
CDH11 homotypic and heterotypic interactions	R-HSA-9833576	7.376878e-01	0.132	0	0
Inhibition of Signaling by Overexpressed EGFR	R-HSA-5638303	7.376878e-01	0.132	0	0
PDE3B signalling	R-HSA-165160	7.376878e-01	0.132	0	0
Noncanonical activation of NOTCH3	R-HSA-9017802	7.376878e-01	0.132	0	0
PKB-mediated events	R-HSA-109703	7.376878e-01	0.132	0	0
Signaling by Overexpressed Wild-Type EGFR in Cancer	R-HSA-5638302	7.376878e-01	0.132	0	0
Activation of caspases through apoptosome-mediated cleavage	R-HSA-111459	7.376878e-01	0.132	0	0
SLIT2:ROBO1 increases RHOA activity	R-HSA-8985586	7.376878e-01	0.132	0	0
Defective CSF2RA causes SMDP4	R-HSA-5688890	7.376878e-01	0.132	0	0
Phase 1 - inactivation of fast Na+ channels	R-HSA-5576894	7.376878e-01	0.132	0	0
Defective CSF2RB causes SMDP5	R-HSA-5688849	7.376878e-01	0.132	0	0
Ligand-receptor interactions	R-HSA-5632681	7.376878e-01	0.132	0	0
NGF-independant TRKA activation	R-HSA-187024	7.376878e-01	0.132	0	0
Pentose phosphate pathway disease	R-HSA-6791465	7.376878e-01	0.132	0	0
Ceramide signalling	R-HSA-193681	7.376878e-01	0.132	0	0
Signalling to p38 via RIT and RIN	R-HSA-187706	7.376878e-01	0.132	0	0
Acetylcholine inhibits contraction of outer hair cells	R-HSA-9667769	7.376878e-01	0.132	0	0
Release of apoptotic factors from the mitochondria	R-HSA-111457	7.376878e-01	0.132	0	0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	R-HSA-446388	7.376878e-01	0.132	0	0
Toxicity of botulinum toxin type E (botE)	R-HSA-5250992	7.376878e-01	0.132	0	0
Regulation of CDH19 Expression and Function	R-HSA-9764302	7.376878e-01	0.132	0	0
Apoptotic factor-mediated response	R-HSA-111471	7.387282e-01	0.132	0	0
Platelet degranulation	R-HSA-114608	7.423598e-01	0.129	0	0
SIRT1 negatively regulates rRNA expression	R-HSA-427359	7.430770e-01	0.129	0	0
Ribosome-associated quality control	R-HSA-9948299	7.446275e-01	0.128	0	0
RNA Polymerase I Promoter Clearance	R-HSA-73854	7.446387e-01	0.128	0	0
Maple Syrup Urine Disease	R-HSA-9865114	7.470636e-01	0.127	0	0
Scavenging by Class F Receptors	R-HSA-3000484	7.470636e-01	0.127	0	0
Regulation of IFNG signaling	R-HSA-877312	7.470636e-01	0.127	0	0
Role of second messengers in netrin-1 signaling	R-HSA-418890	7.470636e-01	0.127	0	0
Activated NTRK2 signals through FRS2 and FRS3	R-HSA-9028731	7.470636e-01	0.127	0	0
GRB2 events in EGFR signaling	R-HSA-179812	7.470636e-01	0.127	0	0
Interleukin-35 Signalling	R-HSA-8984722	7.470636e-01	0.127	0	0
Advanced glycosylation endproduct receptor signaling	R-HSA-879415	7.470636e-01	0.127	0	0
Interleukin-15 signaling	R-HSA-8983432	7.470636e-01	0.127	0	0
OAS antiviral response	R-HSA-8983711	7.470636e-01	0.127	0	0
Potential therapeutics for SARS	R-HSA-9679191	7.470773e-01	0.127	0	0
Cytoprotection by HMOX1	R-HSA-9707564	7.508165e-01	0.124	0	0
HCMV Late Events	R-HSA-9610379	7.531895e-01	0.123	0	0
HCMV Infection	R-HSA-9609646	7.536637e-01	0.123	0	0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	R-HSA-6811558	7.577297e-01	0.120	0	0
Acyl chain remodelling of PS	R-HSA-1482801	7.601737e-01	0.119	0	0
Synthesis of PIPs at the early endosome membrane	R-HSA-1660516	7.601737e-01	0.119	0	0
Formation of the nephric duct	R-HSA-9830364	7.601737e-01	0.119	0	0
PI-3K cascade:FGFR3	R-HSA-5654710	7.641102e-01	0.117	0	0
Signaling by FGFR2 IIIa TM	R-HSA-8851708	7.641102e-01	0.117	0	0
SARS-CoV-2 Genome Replication and Transcription	R-HSA-9694682	7.641102e-01	0.117	0	0
Amine ligand-binding receptors	R-HSA-375280	7.645755e-01	0.117	0	0
Major pathway of rRNA processing in the nucleolus and cytosol	R-HSA-6791226	7.647478e-01	0.116	0	0
Positive epigenetic regulation of rRNA expression	R-HSA-5250913	7.666920e-01	0.115	0	0
Transcriptional and post-translational regulation of MITF-M expression and activity	R-HSA-9856649	7.666920e-01	0.115	0	0
RNA Polymerase I Transcription	R-HSA-73864	7.715841e-01	0.113	0	0
G alpha (s) signalling events	R-HSA-418555	7.736507e-01	0.111	0	0
C-type lectin receptors (CLRs)	R-HSA-5621481	7.736507e-01	0.111	0	0
Regulation of actin dynamics for phagocytic cup formation	R-HSA-2029482	7.746001e-01	0.111	0	0
Cellular response to hypoxia	R-HSA-1234174	7.759294e-01	0.110	0	0
Acetylcholine binding and downstream events	R-HSA-181431	7.763057e-01	0.110	0	0
FGFR4 ligand binding and activation	R-HSA-190322	7.763057e-01	0.110	0	0
Postsynaptic nicotinic acetylcholine receptors	R-HSA-622327	7.763057e-01	0.110	0	0
NFE2L2 regulating tumorigenic genes	R-HSA-9818030	7.763057e-01	0.110	0	0
IL-6-type cytokine receptor ligand interactions	R-HSA-6788467	7.763057e-01	0.110	0	0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	R-HSA-9029558	7.763057e-01	0.110	0	0
ATF6 (ATF6-alpha) activates chaperones	R-HSA-381033	7.763057e-01	0.110	0	0
Erythropoietin activates STAT5	R-HSA-9027283	7.781035e-01	0.109	0	0
STAT5 Activation	R-HSA-9645135	7.781035e-01	0.109	0	0
Uncoating of the HIV Virion	R-HSA-162585	7.781035e-01	0.109	0	0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD	R-HSA-9865125	7.781035e-01	0.109	0	0
Small interfering RNA (siRNA) biogenesis	R-HSA-426486	7.781035e-01	0.109	0	0
Defective factor VIII causes hemophilia A	R-HSA-9662001	7.781035e-01	0.109	0	0
Signaling by LTK in cancer	R-HSA-9842640	7.781035e-01	0.109	0	0
Leukotriene receptors	R-HSA-391906	7.781035e-01	0.109	0	0
VLDL assembly	R-HSA-8866423	7.781035e-01	0.109	0	0
Nuclear RNA decay	R-HSA-9930044	7.791391e-01	0.108	0	0
RAS processing	R-HSA-9648002	7.793764e-01	0.108	0	0
Plasma lipoprotein clearance	R-HSA-8964043	7.793764e-01	0.108	0	0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	R-HSA-110373	7.811871e-01	0.107	0	0
Suppression of phagosomal maturation	R-HSA-9637687	7.811871e-01	0.107	0	0
Regulation of beta-cell development	R-HSA-186712	7.862540e-01	0.104	0	0
VxPx cargo-targeting to cilium	R-HSA-5620916	7.874492e-01	0.104	0	0
SARS-CoV Infections	R-HSA-9679506	7.901317e-01	0.102	0	0
Viral mRNA Translation	R-HSA-192823	7.903247e-01	0.102	0	0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	R-HSA-73779	7.960119e-01	0.099	0	0
mRNA Splicing - Minor Pathway	R-HSA-72165	7.964637e-01	0.099	0	0
Processive synthesis on the C-strand of the telomere	R-HSA-174414	8.007107e-01	0.097	0	0
SHC-mediated cascade:FGFR2	R-HSA-5654699	8.007107e-01	0.097	0	0
Signaling by FGFR3 in disease	R-HSA-5655332	8.007107e-01	0.097	0	0
ER Quality Control Compartment (ERQC)	R-HSA-901032	8.007107e-01	0.097	0	0
Removal of the Flap Intermediate	R-HSA-69166	8.025437e-01	0.096	0	0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV	R-HSA-9859138	8.025437e-01	0.096	0	0
CLEC7A (Dectin-1) induces NFAT activation	R-HSA-5607763	8.025437e-01	0.096	0	0
Zinc transporters	R-HSA-435354	8.025437e-01	0.096	0	0
Signaling by Insulin receptor	R-HSA-74752	8.037613e-01	0.095	0	0
Early Phase of HIV Life Cycle	R-HSA-162594	8.088378e-01	0.092	0	0
Intrinsic Pathway of Fibrin Clot Formation	R-HSA-140837	8.088378e-01	0.092	0	0
NOTCH4 Intracellular Domain Regulates Transcription	R-HSA-9013695	8.088378e-01	0.092	0	0
RSV-host interactions	R-HSA-9833110	8.110416e-01	0.091	0	0
RUNX3 Regulates Immune Response and Cell Migration	R-HSA-8949275	8.122941e-01	0.090	0	0
NOSTRIN mediated eNOS trafficking	R-HSA-203641	8.122941e-01	0.090	0	0
PP2A-mediated dephosphorylation of key metabolic factors	R-HSA-163767	8.122941e-01	0.090	0	0
Netrin mediated repulsion signals	R-HSA-418886	8.122941e-01	0.090	0	0
IFNG signaling activates MAPKs	R-HSA-9732724	8.122941e-01	0.090	0	0
Pre-NOTCH Processing in the Endoplasmic Reticulum	R-HSA-1912399	8.122941e-01	0.090	0	0
SLBP independent Processing of Histone Pre-mRNAs	R-HSA-111367	8.122941e-01	0.090	0	0
MET activates PI3K/AKT signaling	R-HSA-8851907	8.122941e-01	0.090	0	0
VLDL clearance	R-HSA-8964046	8.122941e-01	0.090	0	0
LDL remodeling	R-HSA-8964041	8.122941e-01	0.090	0	0
Ca2+ activated K+ channels	R-HSA-1296052	8.122941e-01	0.090	0	0
Activation of TRKA receptors	R-HSA-187015	8.122941e-01	0.090	0	0
Phase 3 - rapid repolarisation	R-HSA-5576890	8.122941e-01	0.090	0	0
Glycoprotein hormones	R-HSA-209822	8.122941e-01	0.090	0	0
Nef Mediated CD4 Down-regulation	R-HSA-167590	8.122941e-01	0.090	0	0
Maturation of replicase proteins	R-HSA-9694301	8.122941e-01	0.090	0	0
Calnexin/calreticulin cycle	R-HSA-901042	8.138799e-01	0.089	0	0
Activation of AMPK downstream of NMDARs	R-HSA-9619483	8.187985e-01	0.087	0	0
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	8.246406e-01	0.084	0	0
G alpha (z) signalling events	R-HSA-418597	8.247563e-01	0.084	0	0
Intraflagellar transport	R-HSA-5620924	8.249625e-01	0.084	0	0
NGF-stimulated transcription	R-HSA-9031628	8.249625e-01	0.084	0	0
Signaling by PDGF	R-HSA-186797	8.253684e-01	0.083	0	0
G beta:gamma signalling through BTK	R-HSA-8964315	8.260090e-01	0.083	0	0
Phospholipase C-mediated cascade; FGFR4	R-HSA-5654228	8.260090e-01	0.083	0	0
Processive synthesis on the lagging strand	R-HSA-69183	8.260090e-01	0.083	0	0
RNA Polymerase II HIV Promoter Escape	R-HSA-167162	8.263573e-01	0.083	0	0
HIV Transcription Initiation	R-HSA-167161	8.263573e-01	0.083	0	0
RNA Polymerase II Transcription Initiation	R-HSA-75953	8.263573e-01	0.083	0	0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	R-HSA-9615017	8.263573e-01	0.083	0	0
Translation of Structural Proteins	R-HSA-9683701	8.263573e-01	0.083	0	0
FRS-mediated FGFR3 signaling	R-HSA-5654706	8.283786e-01	0.082	0	0
TNFR2 non-canonical NF-kB pathway	R-HSA-5668541	8.300570e-01	0.081	0	0
DNA Replication	R-HSA-69306	8.307026e-01	0.081	0	0
Neutrophil degranulation	R-HSA-6798695	8.307425e-01	0.081	0	0
mRNA Capping	R-HSA-72086	8.355111e-01	0.078	0	0
rRNA modification in the nucleus and cytosol	R-HSA-6790901	8.371090e-01	0.077	0	0
Synthesis of DNA	R-HSA-69239	8.392755e-01	0.076	0	0
Class I MHC mediated antigen processing & presentation	R-HSA-983169	8.398459e-01	0.076	0	0
RNA Polymerase I Transcription Initiation	R-HSA-73762	8.401218e-01	0.076	0	0
Reverse Transcription of HIV RNA	R-HSA-162589	8.412181e-01	0.075	0	0
Minus-strand DNA synthesis	R-HSA-164516	8.412181e-01	0.075	0	0
EGFR interacts with phospholipase C-gamma	R-HSA-212718	8.412181e-01	0.075	0	0
phospho-PLA2 pathway	R-HSA-111995	8.412181e-01	0.075	0	0
Activated NTRK2 signals through PI3K	R-HSA-9028335	8.412181e-01	0.075	0	0
Highly calcium permeable nicotinic acetylcholine receptors	R-HSA-629597	8.412181e-01	0.075	0	0
FGFR1b ligand binding and activation	R-HSA-190370	8.412181e-01	0.075	0	0
MET receptor recycling	R-HSA-8875656	8.412181e-01	0.075	0	0
Axonal growth inhibition (RHOA activation)	R-HSA-193634	8.412181e-01	0.075	0	0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	R-HSA-8939242	8.412181e-01	0.075	0	0
Activation of RAS in B cells	R-HSA-1169092	8.412181e-01	0.075	0	0
Fructose biosynthesis	R-HSA-5652227	8.412181e-01	0.075	0	0
Interleukin-9 signaling	R-HSA-8985947	8.412181e-01	0.075	0	0
TGFBR3 PTM regulation	R-HSA-9839383	8.412181e-01	0.075	0	0
Nucleotide salvage defects	R-HSA-9734207	8.412181e-01	0.075	0	0
Neurotransmitter uptake and metabolism In glial cells	R-HSA-112313	8.412181e-01	0.075	0	0
Astrocytic Glutamate-Glutamine Uptake And Metabolism	R-HSA-210455	8.412181e-01	0.075	0	0
Activated NTRK2 signals through FYN	R-HSA-9032500	8.412181e-01	0.075	0	0
Alpha-defensins	R-HSA-1462054	8.412181e-01	0.075	0	0
Sodium/Proton exchangers	R-HSA-425986	8.412181e-01	0.075	0	0
Interleukin-23 signaling	R-HSA-9020933	8.412181e-01	0.075	0	0
Base Excision Repair	R-HSA-73884	8.419491e-01	0.075	0	0
Adaptive Immune System	R-HSA-1280218	8.420169e-01	0.075	0	0
G1/S-Specific Transcription	R-HSA-69205	8.441005e-01	0.074	0	0
PI-3K cascade:FGFR1	R-HSA-5654689	8.461802e-01	0.073	0	0
WNT5:FZD7-mediated leishmania damping	R-HSA-9673324	8.469330e-01	0.072	0	0
Killing mechanisms	R-HSA-9664420	8.469330e-01	0.072	0	0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	8.469330e-01	0.072	0	0
Fcgamma receptor (FCGR) dependent phagocytosis	R-HSA-2029480	8.474762e-01	0.072	0	0
Antigen processing-Cross presentation	R-HSA-1236975	8.479465e-01	0.072	0	0
Cargo trafficking to the periciliary membrane	R-HSA-5620920	8.483567e-01	0.071	0	0
ABC transporter disorders	R-HSA-5619084	8.489884e-01	0.071	0	0
Adipogenesis	R-HSA-9843745	8.494277e-01	0.071	0	0
Respiratory Syncytial Virus Infection Pathway	R-HSA-9820952	8.519774e-01	0.070	0	0
RNA Polymerase II Promoter Escape	R-HSA-73776	8.529897e-01	0.069	0	0
Defective pyroptosis	R-HSA-9710421	8.529897e-01	0.069	0	0
Response of Mtb to phagocytosis	R-HSA-9637690	8.529897e-01	0.069	0	0
rRNA processing in the nucleus and cytosol	R-HSA-8868773	8.532903e-01	0.069	0	0
TRAF6 mediated IRF7 activation	R-HSA-933541	8.576229e-01	0.067	0	0
Regulation of cholesterol biosynthesis by SREBP (SREBF)	R-HSA-1655829	8.586378e-01	0.066	0	0
Telomere Maintenance	R-HSA-157579	8.613583e-01	0.065	0	0
Regulation of PTEN mRNA translation	R-HSA-8943723	8.623543e-01	0.064	0	0
RNA Pol II CTD phosphorylation and interaction with CE	R-HSA-77075	8.623543e-01	0.064	0	0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	R-HSA-167160	8.623543e-01	0.064	0	0
Response of EIF2AK1 (HRI) to heme deficiency	R-HSA-9648895	8.623543e-01	0.064	0	0
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	8.647880e-01	0.063	0	0
SHC1 events in ERBB4 signaling	R-HSA-1250347	8.655415e-01	0.063	0	0
Acetylcholine regulates insulin secretion	R-HSA-399997	8.655415e-01	0.063	0	0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	R-HSA-6804114	8.655415e-01	0.063	0	0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	R-HSA-9651496	8.655415e-01	0.063	0	0
p75NTR regulates axonogenesis	R-HSA-193697	8.656866e-01	0.063	0	0
MASTL Facilitates Mitotic Progression	R-HSA-2465910	8.656866e-01	0.063	0	0
NOTCH4 Activation and Transmission of Signal to the Nucleus	R-HSA-9013700	8.656866e-01	0.063	0	0
Degradation of GABA	R-HSA-916853	8.656866e-01	0.063	0	0
Toxicity of botulinum toxin type A (botA)	R-HSA-5250968	8.656866e-01	0.063	0	0
Interleukin-1 processing	R-HSA-448706	8.656866e-01	0.063	0	0
Zinc influx into cells by the SLC39 gene family	R-HSA-442380	8.656866e-01	0.063	0	0
RNA polymerase II transcribes snRNA genes	R-HSA-6807505	8.680663e-01	0.061	0	0
XBP1(S) activates chaperone genes	R-HSA-381038	8.680663e-01	0.061	0	0
Triglyceride metabolism	R-HSA-8979227	8.700732e-01	0.060	0	0
Elastic fibre formation	R-HSA-1566948	8.701501e-01	0.060	0	0
RNA Polymerase II Transcription Initiation And Promoter Clearance	R-HSA-76042	8.761759e-01	0.057	0	0
Amyloid fiber formation	R-HSA-977225	8.764696e-01	0.057	0	0
Translocation of ZAP-70 to Immunological synapse	R-HSA-202430	8.770134e-01	0.057	0	0
Complex III assembly	R-HSA-9865881	8.770134e-01	0.057	0	0
DNA strand elongation	R-HSA-69190	8.780671e-01	0.056	0	0
Cross-presentation of soluble exogenous antigens (endosomes)	R-HSA-1236978	8.817316e-01	0.055	0	0
B-WICH complex positively regulates rRNA expression	R-HSA-5250924	8.825174e-01	0.054	0	0
ABC-family proteins mediated transport	R-HSA-382556	8.847319e-01	0.053	0	0
2-LTR circle formation	R-HSA-164843	8.863856e-01	0.052	0	0
OADH complex synthesizes glutaryl-CoA from 2-OA	R-HSA-9858328	8.863856e-01	0.052	0	0
Activation of Ca-permeable Kainate Receptor	R-HSA-451308	8.863856e-01	0.052	0	0
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	R-HSA-629594	8.863856e-01	0.052	0	0
Regulation of CDH11 function	R-HSA-9762292	8.863856e-01	0.052	0	0
TET1,2,3 and TDG demethylate DNA	R-HSA-5221030	8.863856e-01	0.052	0	0
Metabolism of serotonin	R-HSA-380612	8.863856e-01	0.052	0	0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	R-HSA-2151209	8.863856e-01	0.052	0	0
CASP4 inflammasome assembly	R-HSA-9948001	8.863856e-01	0.052	0	0
MET activates RAP1 and RAC1	R-HSA-8875555	8.863856e-01	0.052	0	0
Arachidonate production from DAG	R-HSA-426048	8.863856e-01	0.052	0	0
Cross-presentation of particulate exogenous antigens (phagosomes)	R-HSA-1236973	8.863856e-01	0.052	0	0
Maturation of spike protein	R-HSA-9683686	8.863856e-01	0.052	0	0
Defective factor IX causes hemophilia B	R-HSA-9668250	8.863856e-01	0.052	0	0
Sperm Motility And Taxes	R-HSA-1300642	8.863856e-01	0.052	0	0
MAPK3 (ERK1) activation	R-HSA-110056	8.863856e-01	0.052	0	0
Peptide hormone biosynthesis	R-HSA-209952	8.863856e-01	0.052	0	0
Serotonin receptors	R-HSA-390666	8.863856e-01	0.052	0	0
Sealing of the nuclear envelope (NE) by ESCRT-III	R-HSA-9668328	8.899592e-01	0.051	0	0
FRS-mediated FGFR1 signaling	R-HSA-5654693	8.902686e-01	0.050	0	0
PI-3K cascade:FGFR2	R-HSA-5654695	8.902686e-01	0.050	0	0
Polymerase switching on the C-strand of the telomere	R-HSA-174411	8.902686e-01	0.050	0	0
PCNA-Dependent Long Patch Base Excision Repair	R-HSA-5651801	8.966671e-01	0.047	0	0
G beta:gamma signalling through PLC beta	R-HSA-418217	8.966671e-01	0.047	0	0
GAB1 signalosome	R-HSA-180292	8.966671e-01	0.047	0	0
Presynaptic function of Kainate receptors	R-HSA-500657	8.966671e-01	0.047	0	0
Cytosolic iron-sulfur cluster assembly	R-HSA-2564830	8.966671e-01	0.047	0	0
Neurotransmitter release cycle	R-HSA-112310	8.989908e-01	0.046	0	0
Developmental Biology	R-HSA-1266738	8.991688e-01	0.046	0	0
Vitamin B5 (pantothenate) metabolism	R-HSA-199220	9.008229e-01	0.045	0	0
Phospholipid metabolism	R-HSA-1483257	9.020768e-01	0.045	0	0
Synthesis of IP2, IP, and Ins in the cytosol	R-HSA-1855183	9.022286e-01	0.045	0	0
FGFR2b ligand binding and activation	R-HSA-190377	9.038957e-01	0.044	0	0
Ionotropic activity of kainate receptors	R-HSA-451306	9.038957e-01	0.044	0	0
vRNP Assembly	R-HSA-192905	9.038957e-01	0.044	0	0
vRNA Synthesis	R-HSA-192814	9.038957e-01	0.044	0	0
Chylomicron assembly	R-HSA-8963888	9.038957e-01	0.044	0	0
CD163 mediating an anti-inflammatory response	R-HSA-9662834	9.038957e-01	0.044	0	0
LGI-ADAM interactions	R-HSA-5682910	9.038957e-01	0.044	0	0
Biosynthesis of DPAn-3-derived maresins	R-HSA-9026290	9.038957e-01	0.044	0	0
Prostanoid ligand receptors	R-HSA-391908	9.038957e-01	0.044	0	0
Cellular response to starvation	R-HSA-9711097	9.047097e-01	0.043	0	0
TP53 Regulates Metabolic Genes	R-HSA-5628897	9.049556e-01	0.043	0	0
Gluconeogenesis	R-HSA-70263	9.051454e-01	0.043	0	0
Pre-NOTCH Processing in Golgi	R-HSA-1912420	9.095805e-01	0.041	0	0
Diseases of hemostasis	R-HSA-9671793	9.095805e-01	0.041	0	0
Crosslinking of collagen fibrils	R-HSA-2243919	9.095805e-01	0.041	0	0
Developmental Lineage of Mammary Gland Alveolar Cells	R-HSA-9927426	9.107279e-01	0.041	0	0
Telomere C-strand (Lagging Strand) Synthesis	R-HSA-174417	9.113092e-01	0.040	0	0
IRE1alpha activates chaperones	R-HSA-381070	9.120581e-01	0.040	0	0
RNA Polymerase I Transcription Termination	R-HSA-73863	9.129981e-01	0.040	0	0
Signaling by BMP	R-HSA-201451	9.129981e-01	0.040	0	0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	R-HSA-193807	9.129981e-01	0.040	0	0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	R-HSA-532668	9.134071e-01	0.039	0	0
PI3K events in ERBB4 signaling	R-HSA-1250342	9.187080e-01	0.037	0	0
Signaling by activated point mutants of FGFR1	R-HSA-1839122	9.187080e-01	0.037	0	0
Sema4D mediated inhibition of cell attachment and migration	R-HSA-416550	9.187080e-01	0.037	0	0
Viral RNP Complexes in the Host Cell Nucleus	R-HSA-168330	9.187080e-01	0.037	0	0
Synthesis of diphthamide-EEF2	R-HSA-5358493	9.187080e-01	0.037	0	0
Formation of ATP by chemiosmotic coupling	R-HSA-163210	9.209689e-01	0.036	0	0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	R-HSA-9609523	9.209689e-01	0.036	0	0
Signaling by NODAL	R-HSA-1181150	9.209689e-01	0.036	0	0
Mitochondrial iron-sulfur cluster biogenesis	R-HSA-1362409	9.209689e-01	0.036	0	0
Protein hydroxylation	R-HSA-9629569	9.209689e-01	0.036	0	0
Pregnenolone biosynthesis	R-HSA-196108	9.209689e-01	0.036	0	0
Eicosanoid ligand-binding receptors	R-HSA-391903	9.209689e-01	0.036	0	0
Signaling by FGFR2 in disease	R-HSA-5655253	9.210358e-01	0.036	0	0
FRS-mediated FGFR2 signaling	R-HSA-5654700	9.226770e-01	0.035	0	0
Telomere Extension By Telomerase	R-HSA-171319	9.226770e-01	0.035	0	0
Activation of kainate receptors upon glutamate binding	R-HSA-451326	9.226770e-01	0.035	0	0
Transport to the Golgi and subsequent modification	R-HSA-948021	9.238482e-01	0.034	0	0
Pyruvate metabolism	R-HSA-70268	9.250517e-01	0.034	0	0
Hemostasis	R-HSA-109582	9.251623e-01	0.034	0	0
tRNA modification in the nucleus and cytosol	R-HSA-6782315	9.261215e-01	0.033	0	0
Mitochondrial protein degradation	R-HSA-9837999	9.289854e-01	0.032	0	0
Extension of Telomeres	R-HSA-180786	9.298246e-01	0.032	0	0
MyD88 deficiency (TLR2/4)	R-HSA-5602498	9.309957e-01	0.031	0	0
G-protein activation	R-HSA-202040	9.309957e-01	0.031	0	0
Lagging Strand Synthesis	R-HSA-69186	9.309957e-01	0.031	0	0
Phenylalanine metabolism	R-HSA-8964208	9.309957e-01	0.031	0	0
Synthesis, secretion, and deacylation of Ghrelin	R-HSA-422085	9.309957e-01	0.031	0	0
NOTCH2 intracellular domain regulates transcription	R-HSA-2197563	9.312381e-01	0.031	0	0
Proline catabolism	R-HSA-70688	9.312381e-01	0.031	0	0
Biosynthesis of DPAn-3-derived protectins and resolvins	R-HSA-9026286	9.312381e-01	0.031	0	0
Diseases associated with surfactant metabolism	R-HSA-5687613	9.312381e-01	0.031	0	0
Trafficking and processing of endosomal TLR	R-HSA-1679131	9.312381e-01	0.031	0	0
Synthesis of GDP-mannose	R-HSA-446205	9.312381e-01	0.031	0	0
Polymerase switching	R-HSA-69091	9.312381e-01	0.031	0	0
Leading Strand Synthesis	R-HSA-69109	9.312381e-01	0.031	0	0
Serotonin clearance from the synaptic cleft	R-HSA-380615	9.312381e-01	0.031	0	0
Estrogen biosynthesis	R-HSA-193144	9.312381e-01	0.031	0	0
Glucagon-type ligand receptors	R-HSA-420092	9.313603e-01	0.031	0	0
Regulation of pyruvate dehydrogenase (PDH) complex	R-HSA-204174	9.313603e-01	0.031	0	0
Gap junction trafficking	R-HSA-190828	9.341852e-01	0.030	0	0
Uptake and actions of bacterial toxins	R-HSA-5339562	9.345441e-01	0.029	0	0
Iron uptake and transport	R-HSA-917937	9.347015e-01	0.029	0	0
Thrombin signalling through proteinase activated receptors (PARs)	R-HSA-456926	9.391371e-01	0.027	0	0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	R-HSA-1474151	9.391371e-01	0.027	0	0
IRAK4 deficiency (TLR2/4)	R-HSA-5603041	9.398099e-01	0.027	0	0
Glutathione synthesis and recycling	R-HSA-174403	9.398099e-01	0.027	0	0
Mitochondrial calcium ion transport	R-HSA-8949215	9.398099e-01	0.027	0	0
Amino acids regulate mTORC1	R-HSA-9639288	9.404966e-01	0.027	0	0
OGDH complex synthesizes succinyl-CoA from 2-OG	R-HSA-9853506	9.418374e-01	0.026	0	0
PDH complex synthesizes acetyl-CoA from PYR	R-HSA-9861559	9.418374e-01	0.026	0	0
FGFR2c ligand binding and activation	R-HSA-190375	9.418374e-01	0.026	0	0
CD28 dependent Vav1 pathway	R-HSA-389359	9.418374e-01	0.026	0	0
FGFR1c ligand binding and activation	R-HSA-190373	9.418374e-01	0.026	0	0
Signaling by activated point mutants of FGFR3	R-HSA-1839130	9.418374e-01	0.026	0	0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	R-HSA-5676594	9.418374e-01	0.026	0	0
PI5P Regulates TP53 Acetylation	R-HSA-6811555	9.418374e-01	0.026	0	0
Reversible hydration of carbon dioxide	R-HSA-1475029	9.418374e-01	0.026	0	0
FGFR3 mutant receptor activation	R-HSA-2033514	9.418374e-01	0.026	0	0
Diseases of nucleotide metabolism	R-HSA-9735804	9.418374e-01	0.026	0	0
Processing of SMDT1	R-HSA-8949664	9.418374e-01	0.026	0	0
rRNA modification in the mitochondrion	R-HSA-6793080	9.418374e-01	0.026	0	0
Maturation of nucleoprotein	R-HSA-9683610	9.418374e-01	0.026	0	0
Metabolism of nitric oxide: NOS3 activation and regulation	R-HSA-202131	9.420853e-01	0.026	0	0
MET promotes cell motility	R-HSA-8875878	9.420853e-01	0.026	0	0
SLC-mediated transport of inorganic anions	R-HSA-9958790	9.420853e-01	0.026	0	0
Interferon alpha/beta signaling	R-HSA-909733	9.438329e-01	0.025	0	0
Molecules associated with elastic fibres	R-HSA-2129379	9.460910e-01	0.024	0	0
Purinergic signaling in leishmaniasis infection	R-HSA-9660826	9.463444e-01	0.024	0	0
Cell recruitment (pro-inflammatory response)	R-HSA-9664424	9.463444e-01	0.024	0	0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	R-HSA-6804115	9.475470e-01	0.023	0	0
Fructose metabolism	R-HSA-5652084	9.475470e-01	0.023	0	0
Ethanol oxidation	R-HSA-71384	9.475470e-01	0.023	0	0
LDL clearance	R-HSA-8964038	9.475470e-01	0.023	0	0
Respiratory syncytial virus (RSV) genome replication, transcription and translation	R-HSA-9820965	9.481664e-01	0.023	0	0
Phospholipase C-mediated cascade; FGFR3	R-HSA-5654227	9.508034e-01	0.022	0	0
Retrograde neurotrophin signalling	R-HSA-177504	9.508034e-01	0.022	0	0
Synthesis of IPs in the nucleus	R-HSA-1855191	9.508034e-01	0.022	0	0
FGFR3c ligand binding and activation	R-HSA-190372	9.508034e-01	0.022	0	0
Transport of fatty acids	R-HSA-804914	9.508034e-01	0.022	0	0
Hydrolysis of LPC	R-HSA-1483115	9.508034e-01	0.022	0	0
Biosynthesis of E-series 18(R)-resolvins	R-HSA-9023661	9.508034e-01	0.022	0	0
Formation of the active cofactor, UDP-glucuronate	R-HSA-173599	9.508034e-01	0.022	0	0
Vitamin B2 (riboflavin) metabolism	R-HSA-196843	9.508034e-01	0.022	0	0
Non-canonical inflammasome activation	R-HSA-9686114	9.508034e-01	0.022	0	0
Malate-aspartate shuttle	R-HSA-9856872	9.508034e-01	0.022	0	0
Glycerophospholipid catabolism	R-HSA-6814848	9.508034e-01	0.022	0	0
Respiratory syncytial virus genome transcription	R-HSA-9828642	9.508034e-01	0.022	0	0
Signal regulatory protein family interactions	R-HSA-391160	9.508034e-01	0.022	0	0
Acyl chain remodeling of CL	R-HSA-1482798	9.508034e-01	0.022	0	0
P2Y receptors	R-HSA-417957	9.508034e-01	0.022	0	0
Inwardly rectifying K+ channels	R-HSA-1296065	9.522997e-01	0.021	0	0
Regulation of ornithine decarboxylase (ODC)	R-HSA-350562	9.522997e-01	0.021	0	0
Plasma lipoprotein assembly, remodeling, and clearance	R-HSA-174824	9.526972e-01	0.021	0	0
Transcriptional regulation of brown and beige adipocyte differentiation	R-HSA-9843743	9.536565e-01	0.021	0	0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	R-HSA-9844594	9.536565e-01	0.021	0	0
Nuclear signaling by ERBB4	R-HSA-1251985	9.536565e-01	0.021	0	0
Biosynthesis of maresins	R-HSA-9018682	9.543296e-01	0.020	0	0
Interleukin-20 family signaling	R-HSA-8854691	9.543296e-01	0.020	0	0
Detoxification of Reactive Oxygen Species	R-HSA-3299685	9.555586e-01	0.020	0	0
Metal ion SLC transporters	R-HSA-425410	9.564327e-01	0.019	0	0
Cardiogenesis	R-HSA-9733709	9.578350e-01	0.019	0	0
Telomere C-strand synthesis initiation	R-HSA-174430	9.583877e-01	0.018	0	0
FGFR3 ligand binding and activation	R-HSA-190239	9.583877e-01	0.018	0	0
Signaling by Activin	R-HSA-1502540	9.583877e-01	0.018	0	0
Events associated with phagocytolytic activity of PMN cells	R-HSA-8941413	9.583877e-01	0.018	0	0
Protein repair	R-HSA-5676934	9.583877e-01	0.018	0	0
ADP signalling through P2Y purinoceptor 1	R-HSA-418592	9.602681e-01	0.018	0	0
TNFs bind their physiological receptors	R-HSA-5669034	9.602681e-01	0.018	0	0
Gap junction trafficking and regulation	R-HSA-157858	9.607979e-01	0.017	0	0
Unfolded Protein Response (UPR)	R-HSA-381119	9.610142e-01	0.017	0	0
Acyl chain remodelling of PC	R-HSA-1482788	9.627633e-01	0.016	0	0
EGR2 and SOX10-mediated initiation of Schwann cell myelination	R-HSA-9619665	9.627633e-01	0.016	0	0
Miscellaneous transport and binding events	R-HSA-5223345	9.627633e-01	0.016	0	0
Developmental Cell Lineages	R-HSA-9734767	9.632219e-01	0.016	0	0
Leishmania phagocytosis	R-HSA-9664417	9.635561e-01	0.016	0	0
FCGR3A-mediated phagocytosis	R-HSA-9664422	9.635561e-01	0.016	0	0
Parasite infection	R-HSA-9664407	9.635561e-01	0.016	0	0
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	R-HSA-2142816	9.648031e-01	0.016	0	0
Entry of Influenza Virion into Host Cell via Endocytosis	R-HSA-168275	9.648031e-01	0.016	0	0
Class I peroxisomal membrane protein import	R-HSA-9603798	9.648031e-01	0.016	0	0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	R-HSA-434316	9.648031e-01	0.016	0	0
KSRP (KHSRP) binds and destabilizes mRNA	R-HSA-450604	9.648031e-01	0.016	0	0
Fructose catabolism	R-HSA-70350	9.648031e-01	0.016	0	0
Synthesis of wybutosine at G37 of tRNA(Phe)	R-HSA-6782861	9.648031e-01	0.016	0	0
Attachment and Entry	R-HSA-9678110	9.648031e-01	0.016	0	0
Atorvastatin ADME	R-HSA-9754706	9.648031e-01	0.016	0	0
Laminin interactions	R-HSA-3000157	9.654614e-01	0.015	0	0
Activation of GABAB receptors	R-HSA-991365	9.670699e-01	0.015	0	0
GABA B receptor activation	R-HSA-977444	9.670699e-01	0.015	0	0
Cytosolic tRNA aminoacylation	R-HSA-379716	9.670699e-01	0.015	0	0
eNOS activation	R-HSA-203615	9.671455e-01	0.015	0	0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	R-HSA-983170	9.671455e-01	0.015	0	0
MET activates PTK2 signaling	R-HSA-8874081	9.699982e-01	0.013	0	0
Diseases of branched-chain amino acid catabolism	R-HSA-9865118	9.699982e-01	0.013	0	0
Sphingolipid catabolism	R-HSA-9845614	9.699982e-01	0.013	0	0
G beta:gamma signalling through CDC42	R-HSA-8964616	9.702298e-01	0.013	0	0
Fibronectin matrix formation	R-HSA-1566977	9.702298e-01	0.013	0	0
Biosynthesis of maresin-like SPMs	R-HSA-9027307	9.702298e-01	0.013	0	0
Transcriptional regulation of testis differentiation	R-HSA-9690406	9.702298e-01	0.013	0	0
Vitamin B6 activation to pyridoxal phosphate	R-HSA-964975	9.702298e-01	0.013	0	0
Glycine degradation	R-HSA-6783984	9.702298e-01	0.013	0	0
Passive transport by Aquaporins	R-HSA-432047	9.702298e-01	0.013	0	0
Synthesis of PG	R-HSA-1483148	9.702298e-01	0.013	0	0
Galactose catabolism	R-HSA-70370	9.702298e-01	0.013	0	0
tRNA modification in the mitochondrion	R-HSA-6787450	9.702298e-01	0.013	0	0
Transferrin endocytosis and recycling	R-HSA-917977	9.710373e-01	0.013	0	0
Acyl chain remodelling of PE	R-HSA-1482839	9.710373e-01	0.013	0	0
Translation of Structural Proteins	R-HSA-9694635	9.722223e-01	0.012	0	0
Formation of paraxial mesoderm	R-HSA-9793380	9.731660e-01	0.012	0	0
Phosphorylation of CD3 and TCR zeta chains	R-HSA-202427	9.739574e-01	0.011	0	0
Insulin processing	R-HSA-264876	9.739574e-01	0.011	0	0
FCERI mediated NF-kB activation	R-HSA-2871837	9.741989e-01	0.011	0	0
FGFR2 mutant receptor activation	R-HSA-1839126	9.744895e-01	0.011	0	0
Glycosphingolipid transport	R-HSA-9845576	9.744895e-01	0.011	0	0
Formation of Fibrin Clot (Clotting Cascade)	R-HSA-140877	9.744895e-01	0.011	0	0
Phospholipase C-mediated cascade: FGFR1	R-HSA-5654219	9.748200e-01	0.011	0	0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	R-HSA-190840	9.748200e-01	0.011	0	0
Biosynthesis of aspirin-triggered D-series resolvins	R-HSA-9020265	9.748200e-01	0.011	0	0
Catecholamine biosynthesis	R-HSA-209905	9.748200e-01	0.011	0	0
Sulfide oxidation to sulfate	R-HSA-1614517	9.748200e-01	0.011	0	0
Interferon gamma signaling	R-HSA-877300	9.748851e-01	0.011	0	0
Somitogenesis	R-HSA-9824272	9.767894e-01	0.010	0	0
Protein localization	R-HSA-9609507	9.770411e-01	0.010	0	0
Insulin receptor recycling	R-HSA-77387	9.774093e-01	0.010	0	0
SLC-mediated transport of organic cations	R-HSA-549127	9.775483e-01	0.010	0	0
Activated point mutants of FGFR2	R-HSA-2033519	9.787027e-01	0.009	0	0
FGFR1 ligand binding and activation	R-HSA-190242	9.787027e-01	0.009	0	0
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	R-HSA-2142670	9.787027e-01	0.009	0	0
Biosynthesis of Lipoxins (LX)	R-HSA-2142700	9.787027e-01	0.009	0	0
Transport of connexons to the plasma membrane	R-HSA-190872	9.787027e-01	0.009	0	0
Organic anion transport by SLC5/17/25 transporters	R-HSA-428643	9.787027e-01	0.009	0	0
Nucleotide-like (purinergic) receptors	R-HSA-418038	9.787027e-01	0.009	0	0
Vitamin D (calciferol) metabolism	R-HSA-196791	9.787027e-01	0.009	0	0
Paracetamol ADME	R-HSA-9753281	9.795752e-01	0.009	0	0
Leishmania infection	R-HSA-9658195	9.795875e-01	0.009	0	0
Parasitic Infection Pathways	R-HSA-9824443	9.795875e-01	0.009	0	0
rRNA processing	R-HSA-72312	9.796984e-01	0.009	0	0
Activation of Matrix Metalloproteinases	R-HSA-1592389	9.804160e-01	0.009	0	0
Synthesis of PC	R-HSA-1483191	9.816926e-01	0.008	0	0
tRNA processing	R-HSA-72306	9.817892e-01	0.008	0	0
Prostacyclin signalling through prostacyclin receptor	R-HSA-392851	9.819869e-01	0.008	0	0
Strand-asynchronous mitochondrial DNA replication	R-HSA-9913635	9.819869e-01	0.008	0	0
Pyrimidine biosynthesis	R-HSA-500753	9.819869e-01	0.008	0	0
Synthesis of 5-eicosatetraenoic acids	R-HSA-2142688	9.819869e-01	0.008	0	0
Maturation of nucleoprotein	R-HSA-9694631	9.819869e-01	0.008	0	0
Pentose phosphate pathway	R-HSA-71336	9.826498e-01	0.008	0	0
RNA Polymerase III Transcription Initiation	R-HSA-76046	9.830329e-01	0.007	0	0
Phospholipase C-mediated cascade; FGFR2	R-HSA-5654221	9.847648e-01	0.007	0	0
Post-chaperonin tubulin folding pathway	R-HSA-389977	9.847648e-01	0.007	0	0
Acyl chain remodelling of PI	R-HSA-1482922	9.847648e-01	0.007	0	0
Common Pathway of Fibrin Clot Formation	R-HSA-140875	9.847648e-01	0.007	0	0
Viral Infection Pathways	R-HSA-9824446	9.851628e-01	0.006	0	0
Respiratory syncytial virus (RSV) attachment and entry	R-HSA-9820960	9.853086e-01	0.006	0	0
Synthesis of glycosylphosphatidylinositol (GPI)	R-HSA-162710	9.853086e-01	0.006	0	0
Developmental Cell Lineages of the Exocrine Pancreas	R-HSA-9820448	9.855539e-01	0.006	0	0
Purine ribonucleoside monophosphate biosynthesis	R-HSA-73817	9.866307e-01	0.006	0	0
Maturation of spike protein	R-HSA-9694548	9.866307e-01	0.006	0	0
Peroxisomal protein import	R-HSA-9033241	9.869851e-01	0.006	0	0
Assembly of collagen fibrils and other multimeric structures	R-HSA-2022090	9.869851e-01	0.006	0	0
FGFR2 ligand binding and activation	R-HSA-190241	9.871144e-01	0.006	0	0
ADP signalling through P2Y purinoceptor 12	R-HSA-392170	9.871144e-01	0.006	0	0
Biosynthesis of E-series 18(S)-resolvins	R-HSA-9018896	9.871144e-01	0.006	0	0
Acyl chain remodelling of PG	R-HSA-1482925	9.871144e-01	0.006	0	0
SLC-mediated transport of neurotransmitters	R-HSA-442660	9.882763e-01	0.005	0	0
GABA receptor activation	R-HSA-977443	9.883930e-01	0.005	0	0
Sphingolipid de novo biosynthesis	R-HSA-1660661	9.883930e-01	0.005	0	0
Recycling of bile acids and salts	R-HSA-159418	9.890032e-01	0.005	0	0
RNA Polymerase III Transcription Initiation From Type 2 Promoter	R-HSA-76066	9.891018e-01	0.005	0	0
Molybdenum cofactor biosynthesis	R-HSA-947581	9.891018e-01	0.005	0	0
Serine metabolism	R-HSA-977347	9.891018e-01	0.005	0	0
Attachment and Entry	R-HSA-9694614	9.891018e-01	0.005	0	0
Neddylation	R-HSA-8951664	9.895091e-01	0.005	0	0
Selenoamino acid metabolism	R-HSA-2408522	9.896673e-01	0.005	0	0
Heme degradation	R-HSA-189483	9.904932e-01	0.004	0	0
RNA Polymerase III Transcription Initiation From Type 3 Promoter	R-HSA-76071	9.907828e-01	0.004	0	0
RNA Polymerase III Transcription Initiation From Type 1 Promoter	R-HSA-76061	9.907828e-01	0.004	0	0
Biosynthesis of D-series resolvins	R-HSA-9018676	9.907828e-01	0.004	0	0
WNT ligand biogenesis and trafficking	R-HSA-3238698	9.907828e-01	0.004	0	0
Neurotoxicity of clostridium toxins	R-HSA-168799	9.907828e-01	0.004	0	0
Nucleotide biosynthesis	R-HSA-8956320	9.911744e-01	0.004	0	0
Gap junction assembly	R-HSA-190861	9.917853e-01	0.004	0	0
RA biosynthesis pathway	R-HSA-5365859	9.917853e-01	0.004	0	0
Synthesis of Leukotrienes (LT) and Eoxins (EX)	R-HSA-2142691	9.921243e-01	0.003	0	0
Free fatty acids regulate insulin secretion	R-HSA-400451	9.922045e-01	0.003	0	0
Synthesis of UDP-N-acetyl-glucosamine	R-HSA-446210	9.922045e-01	0.003	0	0
ABC transporters in lipid homeostasis	R-HSA-1369062	9.922045e-01	0.003	0	0
Diseases of carbohydrate metabolism	R-HSA-5663084	9.926122e-01	0.003	0	0
PERK regulates gene expression	R-HSA-381042	9.929051e-01	0.003	0	0
CYP2E1 reactions	R-HSA-211999	9.934071e-01	0.003	0	0
Assembly of active LPL and LIPC lipase complexes	R-HSA-8963889	9.934071e-01	0.003	0	0
Replacement of protamines by nucleosomes in the male pronucleus	R-HSA-9821993	9.934071e-01	0.003	0	0
Synthesis of dolichyl-phosphate	R-HSA-446199	9.934071e-01	0.003	0	0
RNA Polymerase III Transcription	R-HSA-74158	9.938749e-01	0.003	0	0
RNA Polymerase III Abortive And Retractive Initiation	R-HSA-749476	9.938749e-01	0.003	0	0
Post-translational protein phosphorylation	R-HSA-8957275	9.939640e-01	0.003	0	0
Citric acid cycle (TCA cycle)	R-HSA-71403	9.940971e-01	0.003	0	0
G protein gated Potassium channels	R-HSA-1296059	9.944241e-01	0.002	0	0
Activation of G protein gated Potassium channels	R-HSA-1296041	9.944241e-01	0.002	0	0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	R-HSA-997272	9.944241e-01	0.002	0	0
MicroRNA (miRNA) biogenesis	R-HSA-203927	9.944241e-01	0.002	0	0
Hyaluronan degradation	R-HSA-2160916	9.944241e-01	0.002	0	0
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives	R-HSA-9027604	9.944241e-01	0.002	0	0
Glycogen breakdown (glycogenolysis)	R-HSA-70221	9.944241e-01	0.002	0	0
Fertilization	R-HSA-1187000	9.944241e-01	0.002	0	0
PIWI-interacting RNA (piRNA) biogenesis	R-HSA-5601884	9.944241e-01	0.002	0	0
Synthesis of PA	R-HSA-1483166	9.946448e-01	0.002	0	0
Phenylalanine and tyrosine metabolism	R-HSA-8963691	9.947144e-01	0.002	0	0
Late SARS-CoV-2 Infection Events	R-HSA-9772573	9.948626e-01	0.002	0	0
Disorders of transmembrane transporters	R-HSA-5619115	9.951065e-01	0.002	0	0
SLC transporter disorders	R-HSA-5619102	9.955214e-01	0.002	0	0
Collagen formation	R-HSA-1474290	9.958369e-01	0.002	0	0
Chemokine receptors bind chemokines	R-HSA-380108	9.959883e-01	0.002	0	0
Biosynthesis of DPAn-3 SPMs	R-HSA-9025094	9.960119e-01	0.002	0	0
Triglyceride biosynthesis	R-HSA-75109	9.960119e-01	0.002	0	0
Synthesis of PE	R-HSA-1483213	9.960119e-01	0.002	0	0
Maturation of hRSV A proteins	R-HSA-9828806	9.960119e-01	0.002	0	0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	R-HSA-381771	9.960689e-01	0.002	0	0
tRNA Aminoacylation	R-HSA-379724	9.963409e-01	0.002	0	0
Signaling by Retinoic Acid	R-HSA-5362517	9.963409e-01	0.002	0	0
Azathioprine ADME	R-HSA-9748787	9.965001e-01	0.002	0	0
Maturation of TCA enzymes and regulation of TCA cycle	R-HSA-9854311	9.966117e-01	0.001	0	0
ATF4 activates genes in response to endoplasmic reticulum stress	R-HSA-380994	9.966273e-01	0.001	0	0
Iron assimilation using enterobactin	R-HSA-9638334	9.966273e-01	0.001	0	0
Collagen degradation	R-HSA-1442490	9.967806e-01	0.001	0	0
Endogenous sterols	R-HSA-211976	9.967806e-01	0.001	0	0
Thyroxine biosynthesis	R-HSA-209968	9.971477e-01	0.001	0	0
Biosynthesis of EPA-derived SPMs	R-HSA-9018679	9.971477e-01	0.001	0	0
Immune System	R-HSA-168256	9.971557e-01	0.001	0	0
Interconversion of nucleotide di- and triphosphates	R-HSA-499943	9.972037e-01	0.001	0	0
Regulation of lipid metabolism by PPARalpha	R-HSA-400206	9.972570e-01	0.001	0	0
Neurotransmitter clearance	R-HSA-112311	9.975878e-01	0.001	0	0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	R-HSA-381426	9.976743e-01	0.001	0	0
ROS and RNS production in phagocytes	R-HSA-1222556	9.978116e-01	0.001	0	0
Incretin synthesis, secretion, and inactivation	R-HSA-400508	9.978351e-01	0.001	0	0
Biosynthesis of DPA-derived SPMs	R-HSA-9018683	9.979601e-01	0.001	0	0
Aspartate and asparagine metabolism	R-HSA-8963693	9.979601e-01	0.001	0	0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	R-HSA-983695	9.982712e-01	0.001	0	0
Cobalamin (Cbl, vitamin B12) transport and metabolism	R-HSA-196741	9.983967e-01	0.001	0	0
PPARA activates gene expression	R-HSA-1989781	9.984140e-01	0.001	0	0
Defective B3GALTL causes PpS	R-HSA-5083635	9.985412e-01	0.001	0	0
GPCR downstream signalling	R-HSA-388396	9.986379e-01	0.001	0	0
Integrin cell surface interactions	R-HSA-216083	9.986677e-01	0.001	0	0
Inactivation, recovery and regulation of the phototransduction cascade	R-HSA-2514859	9.988141e-01	0.001	0	0
Translation	R-HSA-72766	9.988750e-01	0.000	0	0
Regulation of TLR by endogenous ligand	R-HSA-5686938	9.989568e-01	0.000	0	0
Hyaluronan metabolism	R-HSA-2142845	9.989568e-01	0.000	0	0
Plasma lipoprotein remodeling	R-HSA-8963899	9.991238e-01	0.000	0	0
Metabolism of polyamines	R-HSA-351202	9.991278e-01	0.000	0	0
Synthesis of bile acids and bile salts	R-HSA-192105	9.992300e-01	0.000	0	0
Glyoxylate metabolism and glycine degradation	R-HSA-389661	9.992472e-01	0.000	0	0
O-glycosylation of TSR domain-containing proteins	R-HSA-5173214	9.993692e-01	0.000	0	0
Lysine catabolism	R-HSA-71064	9.993692e-01	0.000	0	0
Collagen chain trimerization	R-HSA-8948216	9.993692e-01	0.000	0	0
Metabolism of folate and pterines	R-HSA-196757	9.993692e-01	0.000	0	0
Branched-chain amino acid catabolism	R-HSA-70895	9.994447e-01	0.000	0	0
The phototransduction cascade	R-HSA-2514856	9.994447e-01	0.000	0	0
FCGR3A-mediated IL10 synthesis	R-HSA-9664323	9.994652e-01	0.000	0	0
Purine salvage	R-HSA-74217	9.994666e-01	0.000	0	0
FCERI mediated MAPK activation	R-HSA-2871796	9.995445e-01	0.000	0	0
G alpha (q) signalling events	R-HSA-416476	9.995586e-01	0.000	0	0
rRNA processing in the mitochondrion	R-HSA-8868766	9.996186e-01	0.000	0	0
Interleukin-10 signaling	R-HSA-6783783	9.996598e-01	0.000	0	0
Aflatoxin activation and detoxification	R-HSA-5423646	9.996775e-01	0.000	0	0
Nicotinate metabolism	R-HSA-196807	9.996776e-01	0.000	0	0
SLC-mediated transport of amino acids	R-HSA-9958863	9.996776e-01	0.000	0	0
Metabolism of steroid hormones	R-HSA-196071	9.996776e-01	0.000	0	0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	R-HSA-193368	9.996776e-01	0.000	0	0
Collagen biosynthesis and modifying enzymes	R-HSA-1650814	9.997207e-01	0.000	0	0
Scavenging by Class A Receptors	R-HSA-3000480	9.997273e-01	0.000	0	0
Mitochondrial translation initiation	R-HSA-5368286	9.997356e-01	0.000	0	0
Metabolism of amine-derived hormones	R-HSA-209776	9.997416e-01	0.000	0	0
Class B/2 (Secretin family receptors)	R-HSA-373080	9.997470e-01	0.000	0	0
Defensins	R-HSA-1461973	9.998050e-01	0.000	0	0
Bile acid and bile salt metabolism	R-HSA-194068	9.998166e-01	0.000	0	0
Metabolism of cofactors	R-HSA-8978934	9.998187e-01	0.000	0	0
Surfactant metabolism	R-HSA-5683826	9.998351e-01	0.000	0	0
Amino acid transport across the plasma membrane	R-HSA-352230	9.998371e-01	0.000	0	0
Glutathione conjugation	R-HSA-156590	9.998604e-01	0.000	0	0
Degradation of cysteine and homocysteine	R-HSA-1614558	9.998606e-01	0.000	0	0
Carboxyterminal post-translational modifications of tubulin	R-HSA-8955332	9.999003e-01	0.000	0	0
Mitochondrial translation elongation	R-HSA-5389840	9.999118e-01	0.000	0	0
Signaling by GPCR	R-HSA-372790	9.999170e-01	0.000	0	0
FCERI mediated Ca+2 mobilization	R-HSA-2871809	9.999225e-01	0.000	0	0
Glycerophospholipid biosynthesis	R-HSA-1483206	9.999268e-01	0.000	0	0
Cholesterol biosynthesis	R-HSA-191273	9.999345e-01	0.000	0	0
Peptide hormone metabolism	R-HSA-2980736	9.999396e-01	0.000	0	0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	R-HSA-2162123	9.999398e-01	0.000	0	0
Metabolic disorders of biological oxidation enzymes	R-HSA-5579029	9.999434e-01	0.000	0	0
Complex IV assembly	R-HSA-9864848	9.999491e-01	0.000	0	0
Cytosolic sulfonation of small molecules	R-HSA-156584	9.999491e-01	0.000	0	0
Mitochondrial ribosome-associated quality control	R-HSA-9937383	9.999655e-01	0.000	0	0
Glucuronidation	R-HSA-156588	9.999692e-01	0.000	0	0
Diseases associated with O-glycosylation of proteins	R-HSA-3906995	9.999747e-01	0.000	0	0
ECM proteoglycans	R-HSA-3000178	9.999747e-01	0.000	0	0
Metabolism of porphyrins	R-HSA-189445	9.999747e-01	0.000	0	0
Retinoid metabolism and transport	R-HSA-975634	9.999747e-01	0.000	0	0
Dectin-2 family	R-HSA-5621480	9.999814e-01	0.000	0	0
Aspirin ADME	R-HSA-9749641	9.999815e-01	0.000	0	0
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	9.999816e-01	0.000	0	0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	R-HSA-163841	9.999826e-01	0.000	0	0
Anti-inflammatory response favouring Leishmania parasite infection	R-HSA-9662851	9.999855e-01	0.000	0	0
Leishmania parasite growth and survival	R-HSA-9664433	9.999855e-01	0.000	0	0
Mitochondrial translation termination	R-HSA-5419276	9.999867e-01	0.000	0	0
Nucleotide salvage	R-HSA-8956321	9.999905e-01	0.000	0	0
Infection with Mycobacterium tuberculosis	R-HSA-9635486	9.999909e-01	0.000	0	0
Innate Immune System	R-HSA-168249	9.999913e-01	0.000	0	0
Developmental Lineage of Pancreatic Acinar Cells	R-HSA-9925561	9.999928e-01	0.000	0	0
Complex I biogenesis	R-HSA-6799198	9.999932e-01	0.000	0	0
Formation of the cornified envelope	R-HSA-6809371	9.999939e-01	0.000	0	0
Xenobiotics	R-HSA-211981	9.999943e-01	0.000	0	0
Extracellular matrix organization	R-HSA-1474244	9.999946e-01	0.000	0	0
Biosynthesis of DHA-derived SPMs	R-HSA-9018677	9.999947e-01	0.000	0	0
Metabolism of fat-soluble vitamins	R-HSA-6806667	9.999947e-01	0.000	0	0
O-linked glycosylation of mucins	R-HSA-913709	9.999971e-01	0.000	0	0
Asparagine N-linked glycosylation	R-HSA-446203	9.999978e-01	0.000	0	0
Fatty acyl-CoA biosynthesis	R-HSA-75105	9.999979e-01	0.000	0	0
Metabolism of carbohydrates and carbohydrate derivatives	R-HSA-71387	9.999979e-01	0.000	0	0
G alpha (i) signalling events	R-HSA-418594	9.999980e-01	0.000	0	0
Post-translational protein modification	R-HSA-597592	9.999981e-01	0.000	0	0
Metal ion assimilation from the host	R-HSA-9638482	9.999982e-01	0.000	0	0
Purine catabolism	R-HSA-74259	9.999985e-01	0.000	0	0
Transport of vitamins, nucleosides, and related molecules	R-HSA-425397	9.999989e-01	0.000	0	0
Role of phospholipids in phagocytosis	R-HSA-2029485	9.999992e-01	0.000	0	0
Post-translational modification: synthesis of GPI-anchored proteins	R-HSA-163125	9.999993e-01	0.000	0	0
Mitochondrial translation	R-HSA-5368287	9.999994e-01	0.000	0	0
SLC-mediated transport of organic anions	R-HSA-9955298	9.999995e-01	0.000	0	0
Mitochondrial Fatty Acid Beta-Oxidation	R-HSA-77289	9.999996e-01	0.000	0	0
Degradation of the extracellular matrix	R-HSA-1474228	9.999997e-01	0.000	0	0
Peroxisomal lipid metabolism	R-HSA-390918	9.999998e-01	0.000	0	0
Sulfur amino acid metabolism	R-HSA-1614635	9.999999e-01	0.000	0	0
Arachidonate metabolism	R-HSA-2142753	9.999999e-01	0.000	0	0
Disease	R-HSA-1643685	1.000000e+00	0.000	0	0
Metabolism of steroids	R-HSA-8957322	1.000000e+00	0.000	0	0
Cell surface interactions at the vascular wall	R-HSA-202733	1.000000e+00	0.000	0	0
Infectious disease	R-HSA-5663205	1.000000e+00	0.000	0	0
Peptide ligand-binding receptors	R-HSA-375276	1.000000e+00	0.000	0	0
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	1.000000e+00	0.000	0	0
Synthesis of substrates in N-glycan biosythesis	R-HSA-446219	1.000000e+00	0.000	0	0
Metabolism of nucleotides	R-HSA-15869	1.000000e+00	0.000	0	0
Visual phototransduction	R-HSA-2187338	1.000000e+00	0.000	0	0
Aerobic respiration and respiratory electron transport	R-HSA-1428517	1.000000e+00	0.000	0	0
Respiratory electron transport	R-HSA-611105	1.000000e+00	0.000	0	0
Cytochrome P450 - arranged by substrate type	R-HSA-211897	1.000000e+00	0.000	0	0
Antimicrobial peptides	R-HSA-6803157	1.000000e+00	0.000	0	0
Nucleotide catabolism	R-HSA-8956319	1.000000e+00	0.000	0	0
Sphingolipid metabolism	R-HSA-428157	1.000000e+00	0.000	0	0
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	1.000000e+00	0.000	0	0
O-linked glycosylation	R-HSA-5173105	1.000000e+00	0.000	0	0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	R-HSA-446193	1.000000e+00	0.000	0	0
Transport of small molecules	R-HSA-382551	1.000000e+00	0.000	0	0
Biosynthesis of specialized proresolving mediators (SPMs)	R-HSA-9018678	1.000000e+00	0.000	0	0
Drug ADME	R-HSA-9748784	1.000000e+00	0.000	0	0
Keratinization	R-HSA-6805567	1.000000e+00	0.000	0	0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	R-HSA-198933	1.000000e+00	0.000	0	0
Metabolism of proteins	R-HSA-392499	1.000000e+00	0.000	0	0
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	1.000000e+00	0.000	0	0
Phase I - Functionalization of compounds	R-HSA-211945	1.000000e+00	0.000	0	0
SLC-mediated transmembrane transport	R-HSA-425407	1.000000e+00	0.000	0	0
Metabolism of vitamins and cofactors	R-HSA-196854	1.000000e+00	0.000	0	0
Diseases of glycosylation	R-HSA-3781865	1.000000e+00	0.000	0	0
Bacterial Infection Pathways	R-HSA-9824439	1.000000e+00	0.000	0	0
Phase II - Conjugation of compounds	R-HSA-156580	1.000000e+00	0.000	0	0
Glycosaminoglycan metabolism	R-HSA-1630316	1.000000e+00	0.000	0	0
Metabolism of amino acids and derivatives	R-HSA-71291	1.000000e+00	0.000	0	0
Infection with Enterobacteria	R-HSA-9640148	1.000000e+00	0.000	0	0
Expression and translocation of olfactory receptors	R-HSA-9752946	1.000000e+00	-0.000	0	0
Metabolism of lipids	R-HSA-556833	1.000000e+00	-0.000	0	0
Metabolism	R-HSA-1430728	1.000000e+00	-0.000	0	0
GPCR ligand binding	R-HSA-500792	1.000000e+00	-0.000	0	0
Biological oxidations	R-HSA-211859	1.000000e+00	-0.000	0	0
Fatty acid metabolism	R-HSA-8978868	1.000000e+00	-0.000	0	0
Diseases of metabolism	R-HSA-5668914	1.000000e+00	-0.000	0	0
Olfactory Signaling Pathway	R-HSA-381753	1.000000e+00	-0.000	0	0
Sensory Perception	R-HSA-9709957	1.000000e+00	-0.000	0	0

Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download

name	reactome_id	p	-log10p	ref_path	ref_path_lowest
Cellular response to heat stress	R-HSA-3371556	1.110223e-16	15.955	0	0
M Phase	R-HSA-68886	1.110223e-16	15.955	0	0
Cell Cycle, Mitotic	R-HSA-69278	1.110223e-16	15.955	0	0
Axon guidance	R-HSA-422475	1.110223e-16	15.955	0	0
Nervous system development	R-HSA-9675108	1.110223e-16	15.955	0	0
Cellular responses to stimuli	R-HSA-8953897	1.110223e-16	15.955	0	0
Cellular responses to stress	R-HSA-2262752	1.110223e-16	15.955	0	0
Cell Cycle	R-HSA-1640170	3.330669e-16	15.477	1	0
Eukaryotic Translation Elongation	R-HSA-156842	4.440892e-16	15.353	0	0
Signaling by ROBO receptors	R-HSA-376176	5.551115e-16	15.256	0	0
L13a-mediated translational silencing of Ceruloplasmin expression	R-HSA-156827	1.554312e-15	14.808	0	0
GTP hydrolysis and joining of the 60S ribosomal subunit	R-HSA-72706	1.554312e-15	14.808	0	0
Eukaryotic Translation Initiation	R-HSA-72613	1.554312e-15	14.808	0	0
Cap-dependent Translation Initiation	R-HSA-72737	1.554312e-15	14.808	0	0
Regulation of HSF1-mediated heat shock response	R-HSA-3371453	3.330669e-15	14.477	0	0
HSF1-dependent transactivation	R-HSA-3371571	1.076916e-14	13.968	0	0
Peptide chain elongation	R-HSA-156902	3.819167e-14	13.418	0	0
Influenza Infection	R-HSA-168255	5.351275e-14	13.272	0	0
Influenza Viral RNA Transcription and Replication	R-HSA-168273	1.064704e-13	12.973	0	0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	R-HSA-975956	1.342260e-13	12.872	0	0
Formation of a pool of free 40S subunits	R-HSA-72689	1.407763e-13	12.851	0	0
Attenuation phase	R-HSA-3371568	3.386180e-13	12.470	0	0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	R-HSA-9954714	4.285461e-13	12.368	0	0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	R-HSA-9954716	4.432010e-13	12.353	0	0
Ribosome-associated quality control	R-HSA-9948299	9.346968e-13	12.029	0	0
Antiviral mechanism by IFN-stimulated genes	R-HSA-1169410	9.827694e-13	12.008	0	0
Mitotic Prophase	R-HSA-68875	1.093792e-12	11.961	0	0
Metabolism of RNA	R-HSA-8953854	1.640466e-12	11.785	0	0
Signal Transduction	R-HSA-162582	2.415845e-12	11.617	1	0
Regulation of PD-L1(CD274) transcription	R-HSA-9909649	3.947953e-12	11.404	0	0
Nonsense-Mediated Decay (NMD)	R-HSA-927802	4.713119e-12	11.327	0	0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	R-HSA-975957	4.713119e-12	11.327	0	0
Cellular Senescence	R-HSA-2559583	6.550316e-12	11.184	0	0
Response of EIF2AK4 (GCN2) to amino acid deficiency	R-HSA-9633012	6.873280e-12	11.163	0	0
Regulation of expression of SLITs and ROBOs	R-HSA-9010553	6.995404e-12	11.155	0	0
Eukaryotic Translation Termination	R-HSA-72764	9.701018e-12	11.013	0	0
HSF1 activation	R-HSA-3371511	1.216582e-11	10.915	0	0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	R-HSA-427389	1.254796e-11	10.901	0	0
Viral Infection Pathways	R-HSA-9824446	2.087330e-11	10.680	0	0
Formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	2.726652e-11	10.564	0	0
Translocation of SLC2A4 (GLUT4) to the plasma membrane	R-HSA-1445148	3.805700e-11	10.420	0	0
Selenocysteine synthesis	R-HSA-2408557	4.589684e-11	10.338	0	0
Recycling pathway of L1	R-HSA-437239	6.131451e-11	10.212	0	0
Cell-Cell communication	R-HSA-1500931	6.507428e-11	10.187	0	0
SRP-dependent cotranslational protein targeting to membrane	R-HSA-1799339	6.886525e-11	10.162	0	0
Viral mRNA Translation	R-HSA-192823	7.516177e-11	10.124	0	0
Positive epigenetic regulation of rRNA expression	R-HSA-5250913	8.976309e-11	10.047	0	0
DNA Damage/Telomere Stress Induced Senescence	R-HSA-2559586	1.050915e-10	9.978	0	0
Transcriptional regulation by small RNAs	R-HSA-5578749	1.212337e-10	9.916	0	0
Diseases of signal transduction by growth factor receptors and second messengers	R-HSA-5663202	1.342541e-10	9.872	0	0
HCMV Early Events	R-HSA-9609690	3.056545e-10	9.515	0	0
Mitotic Prometaphase	R-HSA-68877	5.213623e-10	9.283	0	0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide	R-HSA-9954709	5.280518e-10	9.277	0	0
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	6.421077e-10	9.192	0	0
Major pathway of rRNA processing in the nucleolus and cytosol	R-HSA-6791226	7.316745e-10	9.136	0	0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	R-HSA-9843970	1.025628e-09	8.989	0	0
Mitotic Anaphase	R-HSA-68882	1.075040e-09	8.969	0	0
Apoptotic execution phase	R-HSA-75153	1.083233e-09	8.965	0	0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	R-HSA-8950505	1.168154e-09	8.932	0	0
Mitotic Metaphase and Anaphase	R-HSA-2555396	1.245166e-09	8.905	0	0
rRNA processing in the nucleus and cytosol	R-HSA-8868773	1.768201e-09	8.752	0	0
Separation of Sister Chromatids	R-HSA-2467813	1.823388e-09	8.739	0	0
Senescence-Associated Secretory Phenotype (SASP)	R-HSA-2559582	1.911126e-09	8.719	0	0
PRC2 methylates histones and DNA	R-HSA-212300	2.336388e-09	8.631	0	0
B-WICH complex positively regulates rRNA expression	R-HSA-5250924	2.446008e-09	8.612	0	0
Cell junction organization	R-HSA-446728	3.264502e-09	8.486	0	0
Assembly of the pre-replicative complex	R-HSA-68867	3.343536e-09	8.476	0	0
DNA Replication Pre-Initiation	R-HSA-69002	4.382802e-09	8.358	0	0
HDACs deacetylate histones	R-HSA-3214815	4.587085e-09	8.338	0	0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)	R-HSA-9845323	4.795057e-09	8.319	0	0
Interleukin-12 signaling	R-HSA-9020591	5.961299e-09	8.225	0	0
RNA Polymerase I Promoter Opening	R-HSA-73728	6.065419e-09	8.217	0	0
Interleukin-12 family signaling	R-HSA-447115	8.270033e-09	8.082	0	0
Defective pyroptosis	R-HSA-9710421	8.890325e-09	8.051	0	0
G2/M Transition	R-HSA-69275	9.322805e-09	8.030	0	0
Apoptosis	R-HSA-109581	1.029653e-08	7.987	0	0
Developmental Biology	R-HSA-1266738	9.937430e-09	8.003	0	0
Diseases of programmed cell death	R-HSA-9645723	1.042934e-08	7.982	0	0
Aggrephagy	R-HSA-9646399	1.062214e-08	7.974	0	0
RUNX1 regulates transcription of genes involved in differentiation of HSCs	R-HSA-8939236	1.155087e-08	7.937	0	0
Mitotic G2-G2/M phases	R-HSA-453274	1.253604e-08	7.902	0	0
SARS-CoV-2-host interactions	R-HSA-9705683	1.450955e-08	7.838	0	0
DNA methylation	R-HSA-5334118	1.467304e-08	7.833	0	0
Regulation of CDH1 Gene Transcription	R-HSA-9764560	1.860501e-08	7.730	0	0
Negative Regulation of CDH1 Gene Transcription	R-HSA-9764725	1.985516e-08	7.702	0	0
Cell Cycle Checkpoints	R-HSA-69620	1.999803e-08	7.699	1	0
Post NMDA receptor activation events	R-HSA-438064	2.898690e-08	7.538	0	0
Oxidative Stress Induced Senescence	R-HSA-2559580	2.911218e-08	7.536	0	0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	R-HSA-110328	2.986473e-08	7.525	0	0
Packaging Of Telomere Ends	R-HSA-171306	3.568026e-08	7.448	0	0
Regulation of T cell activation by CD28 family	R-HSA-388841	3.655715e-08	7.437	0	0
HCMV Infection	R-HSA-9609646	4.116028e-08	7.386	0	0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	R-HSA-190840	4.531747e-08	7.344	0	0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	R-HSA-72662	4.612165e-08	7.336	0	0
Recognition and association of DNA glycosylase with site containing an affected purine	R-HSA-110330	4.954585e-08	7.305	0	0
Inhibition of DNA recombination at telomere	R-HSA-9670095	5.129677e-08	7.290	0	0
Translation initiation complex formation	R-HSA-72649	6.146275e-08	7.211	0	0
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	6.449145e-08	7.190	0	0
Chromatin modifications during the maternal to zygotic transition (MZT)	R-HSA-9821002	7.156390e-08	7.145	0	0
Assembly of the ORC complex at the origin of replication	R-HSA-68616	7.243629e-08	7.140	0	0
L1CAM interactions	R-HSA-373760	7.808595e-08	7.107	0	0
Transport of connexons to the plasma membrane	R-HSA-190872	7.742450e-08	7.111	0	0
G2/M Checkpoints	R-HSA-69481	7.503900e-08	7.125	1	0
SARS-CoV-1-host interactions	R-HSA-9692914	7.774525e-08	7.109	0	0
RNA Polymerase I Promoter Clearance	R-HSA-73854	8.070267e-08	7.093	0	0
SIRT1 negatively regulates rRNA expression	R-HSA-427359	8.775688e-08	7.057	0	0
Condensation of Prophase Chromosomes	R-HSA-2299718	1.056875e-07	6.976	0	0
Cellular response to starvation	R-HSA-9711097	1.084678e-07	6.965	0	0
Recruitment of NuMA to mitotic centrosomes	R-HSA-380320	1.215145e-07	6.915	0	0
RNA Polymerase I Transcription	R-HSA-73864	1.275280e-07	6.894	0	0
The role of GTSE1 in G2/M progression after G2 checkpoint	R-HSA-8852276	1.328216e-07	6.877	0	0
EML4 and NUDC in mitotic spindle formation	R-HSA-9648025	1.362000e-07	6.866	0	0
Regulation of PD-L1(CD274) expression	R-HSA-9909648	1.423137e-07	6.847	0	0
Regulation of Expression and Function of Type I Classical Cadherins	R-HSA-9764274	1.637199e-07	6.786	0	0
Regulation of CDH1 Expression and Function	R-HSA-9764265	1.637199e-07	6.786	0	0
Meiotic synapsis	R-HSA-1221632	1.886566e-07	6.724	0	0
Nuclear Envelope (NE) Reassembly	R-HSA-2995410	1.986104e-07	6.702	0	0
ISG15 antiviral mechanism	R-HSA-1169408	2.253257e-07	6.647	0	0
Selenoamino acid metabolism	R-HSA-2408522	2.590127e-07	6.587	0	0
Gene Silencing by RNA	R-HSA-211000	2.833021e-07	6.548	0	0
Regulation of endogenous retroelements	R-HSA-9842860	2.844786e-07	6.546	0	0
Activation of AMPK downstream of NMDARs	R-HSA-9619483	2.931141e-07	6.533	0	0
rRNA processing	R-HSA-72312	3.136259e-07	6.504	0	0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	3.225716e-07	6.491	0	0
Programmed Cell Death	R-HSA-5357801	3.524321e-07	6.453	0	0
Co-inhibition by PD-1	R-HSA-389948	3.947921e-07	6.404	0	0
Cleavage of the damaged purine	R-HSA-110331	4.097913e-07	6.387	0	0
Ribosomal scanning and start codon recognition	R-HSA-72702	4.162386e-07	6.381	0	0
Developmental Lineage of Mammary Gland Myoepithelial Cells	R-HSA-9927432	4.271775e-07	6.369	0	0
Assembly and cell surface presentation of NMDA receptors	R-HSA-9609736	4.371544e-07	6.359	0	0
mRNA Splicing - Major Pathway	R-HSA-72163	4.414275e-07	6.355	0	0
Transcriptional regulation of granulopoiesis	R-HSA-9616222	4.938146e-07	6.306	0	0
RNA Polymerase I Promoter Escape	R-HSA-73772	5.691235e-07	6.245	0	0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	R-HSA-3371497	5.620160e-07	6.250	0	0
Depurination	R-HSA-73927	5.625984e-07	6.250	0	0
Cytokine Signaling in Immune system	R-HSA-1280215	5.596747e-07	6.252	0	0
Cleavage of the damaged pyrimidine	R-HSA-110329	5.877827e-07	6.231	0	0
Depyrimidination	R-HSA-73928	5.877827e-07	6.231	0	0
TCF dependent signaling in response to WNT	R-HSA-201681	6.238869e-07	6.205	0	0
PKR-mediated signaling	R-HSA-9833482	6.617568e-07	6.179	0	0
Activation of NMDA receptors and postsynaptic events	R-HSA-442755	8.488291e-07	6.071	0	0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	R-HSA-389958	8.731341e-07	6.059	0	0
Regulation of endogenous retroelements by KRAB-ZFP proteins	R-HSA-9843940	8.783206e-07	6.056	0	0
Gap junction trafficking	R-HSA-190828	1.039053e-06	5.983	0	0
Cell-cell junction organization	R-HSA-421270	1.167573e-06	5.933	0	0
Estrogen-dependent gene expression	R-HSA-9018519	1.169043e-06	5.932	0	0
Post-chaperonin tubulin folding pathway	R-HSA-389977	1.263708e-06	5.898	0	0
Apoptotic cleavage of cellular proteins	R-HSA-111465	1.226250e-06	5.911	0	0
Regulation of Homotypic Cell-Cell Adhesion	R-HSA-9759476	1.325024e-06	5.878	0	0
Deposition of new CENPA-containing nucleosomes at the centromere	R-HSA-606279	1.366866e-06	5.864	0	0
Nucleosome assembly	R-HSA-774815	1.366866e-06	5.864	0	0
HATs acetylate histones	R-HSA-3214847	1.467110e-06	5.834	0	0
Adherens junctions interactions	R-HSA-418990	1.628229e-06	5.788	0	0
mRNA Splicing	R-HSA-72172	1.669667e-06	5.777	0	0
Meiotic recombination	R-HSA-912446	1.685161e-06	5.773	0	0
Formation of tubulin folding intermediates by CCT/TriC	R-HSA-389960	1.742785e-06	5.759	0	0
Meiosis	R-HSA-1500620	1.787456e-06	5.748	0	0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	R-HSA-8936459	1.926986e-06	5.715	0	0
Nuclear Envelope Breakdown	R-HSA-2980766	1.968002e-06	5.706	0	0
DNA Replication	R-HSA-69306	2.246213e-06	5.649	0	0
Host Interactions of HIV factors	R-HSA-162909	2.290162e-06	5.640	0	0
Nonhomologous End-Joining (NHEJ)	R-HSA-5693571	2.991265e-06	5.524	0	0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	R-HSA-5693565	3.118954e-06	5.506	0	0
SARS-CoV-1 modulates host translation machinery	R-HSA-9735869	3.185928e-06	5.497	0	0
Base-Excision Repair, AP Site Formation	R-HSA-73929	3.491632e-06	5.457	0	0
Gap junction trafficking and regulation	R-HSA-157858	3.835838e-06	5.416	0	0
Chromatin organization	R-HSA-4839726	4.298254e-06	5.367	0	0
DNA Double Strand Break Response	R-HSA-5693606	5.171416e-06	5.286	0	0
Ub-specific processing proteases	R-HSA-5689880	5.567269e-06	5.254	0	0
Prefoldin mediated transfer of substrate to CCT/TriC	R-HSA-389957	6.168991e-06	5.210	0	0
Signaling by ALK fusions and activated point mutants	R-HSA-9725370	6.453875e-06	5.190	0	0
Signaling by ALK in cancer	R-HSA-9700206	6.453875e-06	5.190	0	0
Interferon Signaling	R-HSA-913531	6.454876e-06	5.190	0	0
Formation of the ternary complex, and subsequently, the 43S complex	R-HSA-72695	6.817641e-06	5.166	0	0
E3 ubiquitin ligases ubiquitinate target proteins	R-HSA-8866654	7.817164e-06	5.107	0	0
Replacement of protamines by nucleosomes in the male pronucleus	R-HSA-9821993	8.796733e-06	5.056	0	0
Chromatin modifying enzymes	R-HSA-3247509	8.817721e-06	5.055	0	0
Transport of Mature Transcript to Cytoplasm	R-HSA-72202	9.436613e-06	5.025	0	0
Signaling by Receptor Tyrosine Kinases	R-HSA-9006934	1.179373e-05	4.928	1	0
ESR-mediated signaling	R-HSA-8939211	1.184233e-05	4.927	0	0
Signaling by WNT	R-HSA-195721	1.218263e-05	4.914	0	0
Transport of Mature mRNA Derived from an Intronless Transcript	R-HSA-159231	1.300798e-05	4.886	0	0
Transcriptional Regulation by E2F6	R-HSA-8953750	1.300798e-05	4.886	1	1
Maternal to zygotic transition (MZT)	R-HSA-9816359	1.317009e-05	4.880	0	0
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	1.340564e-05	4.873	0	0
Glycolysis	R-HSA-70171	1.364291e-05	4.865	0	0
Signaling by Interleukins	R-HSA-449147	1.455496e-05	4.837	0	0
SARS-CoV-1 Infection	R-HSA-9678108	1.587585e-05	4.799	0	0
Transport of Mature mRNAs Derived from Intronless Transcripts	R-HSA-159234	1.682579e-05	4.774	0	0
Interactions of Rev with host cellular proteins	R-HSA-177243	1.682579e-05	4.774	0	0
SARS-CoV-2 Infection	R-HSA-9694516	1.711504e-05	4.767	0	0
Ephrin signaling	R-HSA-3928664	1.746085e-05	4.758	0	0
G2/M DNA damage checkpoint	R-HSA-69473	1.989603e-05	4.701	1	1
Cell-extracellular matrix interactions	R-HSA-446353	1.874150e-05	4.727	0	0
HIV Life Cycle	R-HSA-162587	2.070843e-05	4.684	0	0
Processing of DNA double-strand break ends	R-HSA-5693607	2.315001e-05	4.635	1	1
Amyloid fiber formation	R-HSA-977225	2.315001e-05	4.635	0	0
EPH-Ephrin signaling	R-HSA-2682334	2.471711e-05	4.607	0	0
VEGFA-VEGFR2 Pathway	R-HSA-4420097	2.760299e-05	4.559	0	0
Selective autophagy	R-HSA-9663891	3.072659e-05	4.512	0	0
Sealing of the nuclear envelope (NE) by ESCRT-III	R-HSA-9668328	3.158127e-05	4.501	0	0
Transport of the SLBP independent Mature mRNA	R-HSA-159227	3.158127e-05	4.501	0	0
Smooth Muscle Contraction	R-HSA-445355	3.321553e-05	4.479	0	0
NoRC negatively regulates rRNA expression	R-HSA-427413	3.459608e-05	4.461	0	0
Signaling by BRAF and RAF1 fusions	R-HSA-6802952	3.491508e-05	4.457	0	0
Rev-mediated nuclear export of HIV RNA	R-HSA-165054	3.854484e-05	4.414	0	0
HIV Infection	R-HSA-162906	3.891306e-05	4.410	0	0
Muscle contraction	R-HSA-397014	3.907794e-05	4.408	0	0
Regulation of mRNA stability by proteins that bind AU-rich elements	R-HSA-450531	4.127494e-05	4.384	0	0
Transport of the SLBP Dependant Mature mRNA	R-HSA-159230	4.130619e-05	4.384	0	0
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	R-HSA-2559584	4.634341e-05	4.334	0	0
HCMV Late Events	R-HSA-9610379	4.656204e-05	4.332	0	0
Transport of Mature mRNA derived from an Intron-Containing Transcript	R-HSA-159236	4.908312e-05	4.309	0	0
Nuclear import of Rev protein	R-HSA-180746	5.355742e-05	4.271	0	0
Gap junction assembly	R-HSA-190861	5.355742e-05	4.271	0	0
NS1 Mediated Effects on Host Pathways	R-HSA-168276	4.916646e-05	4.308	0	0
RMTs methylate histone arginines	R-HSA-3214858	5.499636e-05	4.260	0	0
Translation	R-HSA-72766	5.513762e-05	4.259	0	0
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	5.554885e-05	4.255	0	0
Intracellular signaling by second messengers	R-HSA-9006925	6.167410e-05	4.210	0	0
Transcriptional Regulation by TP53	R-HSA-3700989	6.601525e-05	4.180	1	0
Protein ubiquitination	R-HSA-8852135	6.875770e-05	4.163	0	0
Nuclear Pore Complex (NPC) Disassembly	R-HSA-3301854	6.886945e-05	4.162	0	0
Signaling by moderate kinase activity BRAF mutants	R-HSA-6802946	8.461492e-05	4.073	0	0
Signaling downstream of RAS mutants	R-HSA-9649948	8.461492e-05	4.073	0	0
Paradoxical activation of RAF signaling by kinase inactive BRAF	R-HSA-6802955	8.461492e-05	4.073	0	0
Signaling by RAS mutants	R-HSA-6802949	8.461492e-05	4.073	0	0
MAPK family signaling cascades	R-HSA-5683057	8.848625e-05	4.053	0	0
Chaperone Mediated Autophagy	R-HSA-9613829	9.047299e-05	4.043	0	0
SARS-CoV Infections	R-HSA-9679506	9.148133e-05	4.039	0	0
Late Phase of HIV Life Cycle	R-HSA-162599	9.615414e-05	4.017	0	0
SARS-CoV-2 activates/modulates innate and adaptive immune responses	R-HSA-9705671	9.615414e-05	4.017	0	0
Signaling by RAF1 mutants	R-HSA-9656223	9.793176e-05	4.009	0	0
mTORC1-mediated signalling	R-HSA-166208	9.953345e-05	4.002	0	0
Vpr-mediated nuclear import of PICs	R-HSA-180910	1.112547e-04	3.954	0	0
Base Excision Repair	R-HSA-73884	1.113074e-04	3.953	0	0
TP53 Regulates Transcription of DNA Repair Genes	R-HSA-6796648	1.114652e-04	3.953	1	1
Signaling by VEGF	R-HSA-194138	1.118754e-04	3.951	0	0
Deubiquitination	R-HSA-5688426	1.165645e-04	3.933	0	0
Developmental Lineages of the Mammary Gland	R-HSA-9924644	1.182226e-04	3.927	0	0
Oncogenic MAPK signaling	R-HSA-6802957	1.208667e-04	3.918	0	0
MAPK6/MAPK4 signaling	R-HSA-5687128	1.208667e-04	3.918	0	0
Constitutive Signaling by AKT1 E17K in Cancer	R-HSA-5674400	1.345641e-04	3.871	0	0
AURKA Activation by TPX2	R-HSA-8854518	1.238173e-04	3.907	0	0
Developmental Cell Lineages of the Integumentary System	R-HSA-9734779	1.242288e-04	3.906	0	0
Chromosome Maintenance	R-HSA-73886	1.424618e-04	3.846	0	0
Kinesins	R-HSA-983189	1.276765e-04	3.894	0	0
Signaling by NOTCH	R-HSA-157118	1.224955e-04	3.912	0	0
Transcriptional regulation by RUNX1	R-HSA-8878171	1.391256e-04	3.857	0	0
Telomere Maintenance	R-HSA-157579	1.537918e-04	3.813	0	0
Signaling by TGF-beta Receptor Complex	R-HSA-170834	1.537918e-04	3.813	0	0
Striated Muscle Contraction	R-HSA-390522	1.573187e-04	3.803	0	0
Glucose metabolism	R-HSA-70326	2.043345e-04	3.690	0	0
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	2.140366e-04	3.670	0	0
Loss of Nlp from mitotic centrosomes	R-HSA-380259	2.140366e-04	3.670	0	0
Semaphorin interactions	R-HSA-373755	2.140366e-04	3.670	0	0
Interactions of Vpr with host cellular proteins	R-HSA-176033	2.166094e-04	3.664	0	0
Downregulation of ERBB2 signaling	R-HSA-8863795	2.211925e-04	3.655	0	0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	R-HSA-5619107	2.211925e-04	3.655	0	0
Reproduction	R-HSA-1474165	2.223290e-04	3.653	0	0
Regulation of CDH1 Function	R-HSA-9764561	2.223601e-04	3.653	0	0
IP3 and IP4 transport between cytosol and nucleus	R-HSA-1855196	2.823192e-04	3.549	0	0
IP6 and IP7 transport between cytosol and nucleus	R-HSA-1855229	2.823192e-04	3.549	0	0
CaMK IV-mediated phosphorylation of CREB	R-HSA-111932	2.875363e-04	3.541	0	0
Apoptosis induced DNA fragmentation	R-HSA-140342	2.875363e-04	3.541	0	0
AUF1 (hnRNP D0) binds and destabilizes mRNA	R-HSA-450408	3.119034e-04	3.506	0	0
snRNP Assembly	R-HSA-191859	3.131015e-04	3.504	0	0
Metabolism of non-coding RNA	R-HSA-194441	3.131015e-04	3.504	0	0
Pre-NOTCH Transcription and Translation	R-HSA-1912408	3.233258e-04	3.490	0	0
TCR signaling	R-HSA-202403	3.736413e-04	3.428	0	0
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	3.751492e-04	3.426	0	0
Deactivation of the beta-catenin transactivating complex	R-HSA-3769402	3.862253e-04	3.413	0	0
SARS-CoV-2 modulates host translation machinery	R-HSA-9754678	3.868954e-04	3.412	0	0
Mitochondrial unfolded protein response (UPRmt)	R-HSA-9841251	3.979112e-04	3.400	0	0
Infectious disease	R-HSA-5663205	4.048406e-04	3.393	0	0
Autophagy	R-HSA-9612973	4.075767e-04	3.390	0	0
Protein folding	R-HSA-391251	4.197020e-04	3.377	0	0
Activation of HOX genes during differentiation	R-HSA-5619507	4.235500e-04	3.373	0	0
Activation of anterior HOX genes in hindbrain development during early embryogenesis	R-HSA-5617472	4.235500e-04	3.373	0	0
Regulation of PTEN localization	R-HSA-8948747	4.420478e-04	3.355	0	0
IPs transport between nucleus and cytosol	R-HSA-1855170	4.482661e-04	3.348	0	0
Adaptive Immune System	R-HSA-1280218	4.550385e-04	3.342	0	0
Spry regulation of FGF signaling	R-HSA-1295596	5.494273e-04	3.260	0	0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	R-HSA-2173791	5.494273e-04	3.260	0	0
Centrosome maturation	R-HSA-380287	5.012642e-04	3.300	0	0
Chaperonin-mediated protein folding	R-HSA-390466	4.689692e-04	3.329	0	0
Homology Directed Repair	R-HSA-5693538	5.151238e-04	3.288	1	0
COPI-independent Golgi-to-ER retrograde traffic	R-HSA-6811436	4.585447e-04	3.339	0	0
Hedgehog 'off' state	R-HSA-5610787	5.404549e-04	3.267	0	0
Regulation of Glucokinase by Glucokinase Regulatory Protein	R-HSA-170822	5.581398e-04	3.253	0	0
FLT3 signaling by CBL mutants	R-HSA-9706377	6.102473e-04	3.214	0	0
DNA Double-Strand Break Repair	R-HSA-5693532	6.254890e-04	3.204	1	0
Membrane Trafficking	R-HSA-199991	6.981371e-04	3.156	0	0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	R-HSA-8849469	7.234501e-04	3.141	0	0
COPI-dependent Golgi-to-ER retrograde traffic	R-HSA-6811434	7.774002e-04	3.109	0	0
S Phase	R-HSA-69242	7.948142e-04	3.100	0	0
Immune System	R-HSA-168256	8.417896e-04	3.075	0	0
VEGFR2 mediated vascular permeability	R-HSA-5218920	8.520191e-04	3.070	0	0
Sema4D in semaphorin signaling	R-HSA-400685	9.171003e-04	3.038	0	0
Downregulation of ERBB2:ERBB3 signaling	R-HSA-1358803	9.655654e-04	3.015	0	0
EGFR downregulation	R-HSA-182971	1.000996e-03	3.000	0	0
Signaling by ERBB2	R-HSA-1227986	1.012517e-03	2.995	0	0
Neurotransmitter receptors and postsynaptic signal transmission	R-HSA-112314	1.065002e-03	2.973	0	0
Gap junction degradation	R-HSA-190873	1.126655e-03	2.948	0	0
IRAK2 mediated activation of TAK1 complex	R-HSA-937042	1.126655e-03	2.948	0	0
Cilium Assembly	R-HSA-5617833	1.139520e-03	2.943	0	0
Metalloprotease DUBs	R-HSA-5689901	1.159191e-03	2.936	0	0
PIP3 activates AKT signaling	R-HSA-1257604	1.160759e-03	2.935	0	0
Regulation of TP53 Activity	R-HSA-5633007	1.169881e-03	2.932	1	0
MAP kinase activation	R-HSA-450294	1.173738e-03	2.930	0	0
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	1.210845e-03	2.917	0	0
Neutrophil degranulation	R-HSA-6798695	1.219856e-03	2.914	0	0
MTOR signalling	R-HSA-165159	1.222528e-03	2.913	0	0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	R-HSA-5693567	1.284557e-03	2.891	1	0
tRNA processing in the nucleus	R-HSA-6784531	1.356130e-03	2.868	0	0
Membrane binding and targetting of GAG proteins	R-HSA-174490	1.361908e-03	2.866	0	0
Gene expression (Transcription)	R-HSA-74160	1.420133e-03	2.848	1	0
UCH proteinases	R-HSA-5689603	1.433532e-03	2.844	0	0
TNFR1-induced NF-kappa-B signaling pathway	R-HSA-5357956	1.451067e-03	2.838	0	0
Signaling by EGFR	R-HSA-177929	1.485286e-03	2.828	0	0
Macroautophagy	R-HSA-1632852	1.538700e-03	2.813	0	0
Signaling by Non-Receptor Tyrosine Kinases	R-HSA-9006927	1.561831e-03	2.806	0	0
Signaling by PTK6	R-HSA-8848021	1.561831e-03	2.806	0	0
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	1.606619e-03	2.794	0	0
TICAM1,TRAF6-dependent induction of TAK1 complex	R-HSA-9014325	1.682998e-03	2.774	0	0
COPI-mediated anterograde transport	R-HSA-6807878	1.757635e-03	2.755	0	0
Cargo trafficking to the periciliary membrane	R-HSA-5620920	1.831875e-03	2.737	0	0
Synthesis And Processing Of GAG, GAGPOL Polyproteins	R-HSA-174495	1.875143e-03	2.727	0	0
PI3K/AKT Signaling in Cancer	R-HSA-2219528	2.323747e-03	2.634	0	0
RNA Polymerase II Transcription	R-HSA-73857	2.140148e-03	2.670	1	0
Alpha-protein kinase 1 signaling pathway	R-HSA-9645460	2.426506e-03	2.615	0	0
Export of Viral Ribonucleoproteins from Nucleus	R-HSA-168274	2.370099e-03	2.625	0	0
Pre-NOTCH Expression and Processing	R-HSA-1912422	2.447912e-03	2.611	0	0
InlB-mediated entry of Listeria monocytogenes into host cell	R-HSA-8875360	2.526867e-03	2.597	0	0
Sema3A PAK dependent Axon repulsion	R-HSA-399954	2.526867e-03	2.597	0	0
Transport of Ribonucleoproteins into the Host Nucleus	R-HSA-168271	2.535551e-03	2.596	0	0
Mitotic Spindle Checkpoint	R-HSA-69618	2.685204e-03	2.571	0	0
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	2.708989e-03	2.567	0	0
Carboxyterminal post-translational modifications of tubulin	R-HSA-8955332	2.764920e-03	2.558	0	0
Cohesin Loading onto Chromatin	R-HSA-2470946	2.882113e-03	2.540	0	0
Platelet degranulation	R-HSA-114608	2.886085e-03	2.540	0	0
Negative regulation of MET activity	R-HSA-6807004	3.027433e-03	2.519	0	0
Signaling by Nuclear Receptors	R-HSA-9006931	3.065546e-03	2.513	0	0
RET signaling	R-HSA-8853659	3.165792e-03	2.500	0	0
CaM pathway	R-HSA-111997	3.165792e-03	2.500	0	0
Calmodulin induced events	R-HSA-111933	3.165792e-03	2.500	0	0
Negative regulation of FLT3	R-HSA-9706369	3.340080e-03	2.476	0	0
TICAM1-dependent activation of IRF3/IRF7	R-HSA-9013973	3.393295e-03	2.469	0	0
Ca-dependent events	R-HSA-111996	3.498753e-03	2.456	0	0
Epigenetic regulation of gene expression	R-HSA-212165	3.635869e-03	2.439	0	0
Signaling by high-kinase activity BRAF mutants	R-HSA-6802948	3.750736e-03	2.426	0	0
Ovarian tumor domain proteases	R-HSA-5689896	3.750736e-03	2.426	0	0
TRIF (TICAM1)-mediated TLR4 signaling	R-HSA-937061	3.780686e-03	2.422	0	0
MyD88-independent TLR4 cascade	R-HSA-166166	3.780686e-03	2.422	0	0
Signaling by Ligand-Responsive EGFR Variants in Cancer	R-HSA-5637815	3.820582e-03	2.418	0	0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	R-HSA-1236382	3.820582e-03	2.418	0	0
APC-Cdc20 mediated degradation of Nek2A	R-HSA-179409	3.820582e-03	2.418	0	0
TNF signaling	R-HSA-75893	3.836892e-03	2.416	0	0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	R-HSA-2173793	3.836892e-03	2.416	0	0
Cyclin E associated events during G1/S transition	R-HSA-69202	3.863654e-03	2.413	0	0
Interleukin-17 signaling	R-HSA-448424	3.863654e-03	2.413	0	0
TGF-beta receptor signaling activates SMADs	R-HSA-2173789	4.080482e-03	2.389	0	0
DNA Repair	R-HSA-73894	4.102830e-03	2.387	1	0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	R-HSA-442729	4.299454e-03	2.367	0	0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	R-HSA-9828211	4.299454e-03	2.367	0	0
Formation of annular gap junctions	R-HSA-196025	4.299454e-03	2.367	0	0
Myoclonic epilepsy of Lafora	R-HSA-3785653	4.299454e-03	2.367	0	0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	R-HSA-936964	4.338925e-03	2.363	0	0
Signaling by Hedgehog	R-HSA-5358351	4.477432e-03	2.349	0	0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	R-HSA-141444	4.592141e-03	2.338	0	0
Amplification of signal from the kinetochores	R-HSA-141424	4.592141e-03	2.338	0	0
VLDLR internalisation and degradation	R-HSA-8866427	4.620903e-03	2.335	0	0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	R-HSA-442742	4.692041e-03	2.329	0	0
G1/S Transition	R-HSA-69206	4.753007e-03	2.323	0	0
Listeria monocytogenes entry into host cells	R-HSA-8876384	4.765335e-03	2.322	0	0
activated TAK1 mediates p38 MAPK activation	R-HSA-450302	4.765335e-03	2.322	0	0
Assembly Of The HIV Virion	R-HSA-175474	4.765335e-03	2.322	0	0
Golgi-to-ER retrograde transport	R-HSA-8856688	4.813800e-03	2.318	0	0
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	4.825758e-03	2.316	0	0
Cyclin A:Cdk2-associated events at S phase entry	R-HSA-69656	4.884699e-03	2.311	0	0
Regulation of TP53 Expression and Degradation	R-HSA-6806003	5.178419e-03	2.286	0	0
Signaling by MET	R-HSA-6806834	5.301822e-03	2.276	0	0
Cellular responses to mechanical stimuli	R-HSA-9855142	5.436200e-03	2.265	0	0
MAPK1/MAPK3 signaling	R-HSA-5684996	5.439158e-03	2.264	0	0
Switching of origins to a post-replicative state	R-HSA-69052	5.472053e-03	2.262	0	0
DAG and IP3 signaling	R-HSA-1489509	5.476091e-03	2.262	0	0
NEP/NS2 Interacts with the Cellular Export Machinery	R-HSA-168333	5.476091e-03	2.262	0	0
Signaling by Hippo	R-HSA-2028269	5.548396e-03	2.256	0	0
DNA Damage Recognition in GG-NER	R-HSA-5696394	5.565239e-03	2.255	0	0
Drug resistance in ERBB2 KD mutants	R-HSA-9665230	6.803671e-03	2.167	0	0
Drug-mediated inhibition of ERBB2 signaling	R-HSA-9652282	6.803671e-03	2.167	0	0
Resistance of ERBB2 KD mutants to afatinib	R-HSA-9665249	6.803671e-03	2.167	0	0
Resistance of ERBB2 KD mutants to AEE788	R-HSA-9665250	6.803671e-03	2.167	0	0
Drug resistance in ERBB2 TMD/JMD mutants	R-HSA-9665737	6.803671e-03	2.167	0	0
Resistance of ERBB2 KD mutants to tesevatinib	R-HSA-9665245	6.803671e-03	2.167	0	0
Resistance of ERBB2 KD mutants to neratinib	R-HSA-9665246	6.803671e-03	2.167	0	0
Resistance of ERBB2 KD mutants to osimertinib	R-HSA-9665247	6.803671e-03	2.167	0	0
Resistance of ERBB2 KD mutants to sapitinib	R-HSA-9665244	6.803671e-03	2.167	0	0
Resistance of ERBB2 KD mutants to lapatinib	R-HSA-9665251	6.803671e-03	2.167	0	0
Resistance of ERBB2 KD mutants to trastuzumab	R-HSA-9665233	6.803671e-03	2.167	0	0
Negative regulation of FGFR3 signaling	R-HSA-5654732	5.833051e-03	2.234	0	0
Negative regulation of FGFR4 signaling	R-HSA-5654733	6.978254e-03	2.156	0	0
Late endosomal microautophagy	R-HSA-9615710	6.978254e-03	2.156	0	0
RAF activation	R-HSA-5673000	6.560428e-03	2.183	0	0
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	7.226659e-03	2.141	0	0
mRNA 3'-end processing	R-HSA-72187	5.623056e-03	2.250	0	0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	R-HSA-174178	6.409027e-03	2.193	0	0
PKMTs methylate histone lysines	R-HSA-3214841	7.004650e-03	2.155	0	0
Regulation of TNFR1 signaling	R-HSA-5357905	6.303487e-03	2.200	0	0
Clathrin-mediated endocytosis	R-HSA-8856828	7.124921e-03	2.147	0	0
Regulation of TP53 Activity through Methylation	R-HSA-6804760	6.994028e-03	2.155	0	0
Orc1 removal from chromatin	R-HSA-68949	5.623056e-03	2.250	0	0
Caspase-mediated cleavage of cytoskeletal proteins	R-HSA-264870	6.154378e-03	2.211	0	0
RAF/MAP kinase cascade	R-HSA-5673001	5.936576e-03	2.226	0	0
Depolymerization of the Nuclear Lamina	R-HSA-4419969	6.994028e-03	2.155	0	0
Viral Messenger RNA Synthesis	R-HSA-168325	7.207979e-03	2.142	0	0
FLT3 Signaling	R-HSA-9607240	7.004650e-03	2.155	0	0
Maturation of protein E	R-HSA-9694493	7.495665e-03	2.125	0	0
Maturation of protein E	R-HSA-9683683	7.495665e-03	2.125	0	0
Signaling by TGFB family members	R-HSA-9006936	7.516581e-03	2.124	0	0
Organelle biogenesis and maintenance	R-HSA-1852241	7.649556e-03	2.116	0	0
Generic Transcription Pathway	R-HSA-212436	7.657354e-03	2.116	1	0
Formation of the polybromo-BAF (pBAF) complex	R-HSA-9933939	8.011771e-03	2.096	0	0
MAP3K8 (TPL2)-dependent MAPK1/3 activation	R-HSA-5684264	8.011771e-03	2.096	0	0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	R-HSA-975163	8.011771e-03	2.096	0	0
Response of endothelial cells to shear stress	R-HSA-9860931	8.077044e-03	2.093	0	0
Cargo recognition for clathrin-mediated endocytosis	R-HSA-8856825	8.077044e-03	2.093	0	0
Degradation of GLI1 by the proteasome	R-HSA-5610780	8.088766e-03	2.092	0	0
MAP2K and MAPK activation	R-HSA-5674135	8.088766e-03	2.092	0	0
Interleukin-37 signaling	R-HSA-9008059	8.288070e-03	2.082	0	0
MET activates RAP1 and RAC1	R-HSA-8875555	8.509684e-03	2.070	0	0
Establishment of Sister Chromatid Cohesion	R-HSA-2468052	8.509684e-03	2.070	0	0
Josephin domain DUBs	R-HSA-5689877	8.509684e-03	2.070	0	0
CD209 (DC-SIGN) signaling	R-HSA-5621575	8.689530e-03	2.061	0	0
Regulation of signaling by CBL	R-HSA-912631	8.701583e-03	2.060	0	0
APC/C:Cdc20 mediated degradation of Cyclin B	R-HSA-174048	8.701583e-03	2.060	0	0
Death Receptor Signaling	R-HSA-73887	8.760802e-03	2.057	0	0
Mitotic G1 phase and G1/S transition	R-HSA-453279	8.869124e-03	2.052	0	0
PTEN Regulation	R-HSA-6807070	8.952692e-03	2.048	0	0
Regulation of TP53 Degradation	R-HSA-6804757	8.960339e-03	2.048	0	0
Regulation of mitotic cell cycle	R-HSA-453276	9.768431e-03	2.010	0	0
APC/C-mediated degradation of cell cycle proteins	R-HSA-174143	9.768431e-03	2.010	0	0
Trafficking of AMPA receptors	R-HSA-399719	9.776678e-03	2.010	0	0
Regulation of activated PAK-2p34 by proteasome mediated degradation	R-HSA-211733	9.776678e-03	2.010	0	0
Signaling by NTRKs	R-HSA-166520	1.021512e-02	1.991	0	0
TICAM1, RIP1-mediated IKK complex recruitment	R-HSA-168927	1.025111e-02	1.989	0	0
TRAF6-mediated induction of TAK1 complex within TLR4 complex	R-HSA-937072	1.025111e-02	1.989	0	0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways	R-HSA-9755779	1.025111e-02	1.989	0	0
Protein methylation	R-HSA-8876725	1.025111e-02	1.989	0	0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	R-HSA-9735871	1.025111e-02	1.989	0	0
p75NTR signals via NF-kB	R-HSA-193639	1.025111e-02	1.989	0	0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	R-HSA-2173796	1.038734e-02	1.983	0	0
Regulation of RAS by GAPs	R-HSA-5658442	1.064433e-02	1.973	0	0
Sema4D induced cell migration and growth-cone collapse	R-HSA-416572	1.069672e-02	1.971	0	0
Nephrin family interactions	R-HSA-373753	1.069672e-02	1.971	0	0
CREB phosphorylation	R-HSA-199920	1.115761e-02	1.952	0	0
Signaling by NTRK1 (TRKA)	R-HSA-187037	1.134129e-02	1.945	0	0
Signaling by FGFR2	R-HSA-5654738	1.136951e-02	1.944	0	0
InlA-mediated entry of Listeria monocytogenes into host cells	R-HSA-8876493	1.142477e-02	1.942	0	0
Downregulation of SMAD2/3:SMAD4 transcriptional activity	R-HSA-2173795	1.145835e-02	1.941	0	0
Cell death signalling via NRAGE, NRIF and NADE	R-HSA-204998	1.200361e-02	1.921	0	0
EPHB-mediated forward signaling	R-HSA-3928662	1.213312e-02	1.916	0	0
Intra-Golgi and retrograde Golgi-to-ER traffic	R-HSA-6811442	1.221271e-02	1.913	0	0
Signaling by EGFR in Cancer	R-HSA-1643713	1.239929e-02	1.907	0	0
Postmitotic nuclear pore complex (NPC) reformation	R-HSA-9615933	1.239929e-02	1.907	0	0
MET interacts with TNS proteins	R-HSA-8875513	1.239931e-02	1.907	0	0
MET activates PTPN11	R-HSA-8865999	1.239931e-02	1.907	0	0
Regulation of NF-kappa B signaling	R-HSA-9758274	1.290215e-02	1.889	0	0
MHC class II antigen presentation	R-HSA-2132295	1.325754e-02	1.878	0	0
Negative regulation of FGFR1 signaling	R-HSA-5654726	1.334734e-02	1.875	0	0
Regulation of necroptotic cell death	R-HSA-5675482	1.334734e-02	1.875	0	0
Regulation of MECP2 expression and activity	R-HSA-9022692	1.334734e-02	1.875	0	0
Activation of ATR in response to replication stress	R-HSA-176187	1.334734e-02	1.875	1	1
Glutamate binding, activation of AMPA receptors and synaptic plasticity	R-HSA-399721	1.334734e-02	1.875	0	0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	R-HSA-174184	1.353859e-02	1.868	0	0
G-protein mediated events	R-HSA-112040	1.397969e-02	1.855	0	0
Defective Intrinsic Pathway for Apoptosis	R-HSA-9734009	1.463790e-02	1.835	0	0
Regulation of PTEN gene transcription	R-HSA-8943724	1.463854e-02	1.835	0	0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	R-HSA-9824878	1.495436e-02	1.825	0	0
NF-kB is activated and signals survival	R-HSA-209560	1.495436e-02	1.825	0	0
Mitotic Telophase/Cytokinesis	R-HSA-68884	1.495436e-02	1.825	0	0
Regulation of PTEN stability and activity	R-HSA-8948751	1.519355e-02	1.818	0	0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	R-HSA-179419	1.519355e-02	1.818	0	0
Epigenetic regulation by WDR5-containing histone modifying complexes	R-HSA-9917777	1.527562e-02	1.816	0	0
Autodegradation of Cdh1 by Cdh1:APC/C	R-HSA-174084	1.558140e-02	1.807	0	0
Unblocking of NMDA receptors, glutamate binding and activation	R-HSA-438066	1.565005e-02	1.805	0	0
Negative regulation of NMDA receptor-mediated neuronal transmission	R-HSA-9617324	1.565005e-02	1.805	0	0
Ras activation upon Ca2+ influx through NMDA receptor	R-HSA-442982	1.565005e-02	1.805	0	0
FOXO-mediated transcription of cell cycle genes	R-HSA-9617828	1.565005e-02	1.805	0	0
Role of ABL in ROBO-SLIT signaling	R-HSA-428890	1.580771e-02	1.801	0	0
Regulation of innate immune responses to cytosolic DNA	R-HSA-3134975	1.599956e-02	1.796	0	0
PLC beta mediated events	R-HSA-112043	1.628086e-02	1.788	0	0
RNA Polymerase II Transcription Termination	R-HSA-73856	1.628086e-02	1.788	0	0
Platelet activation, signaling and aggregation	R-HSA-76002	1.637225e-02	1.786	0	0
CDK-mediated phosphorylation and removal of Cdc6	R-HSA-69017	1.699736e-02	1.770	0	0
APC/C:Cdc20 mediated degradation of Securin	R-HSA-174154	1.755884e-02	1.756	0	0
Negative regulation of FGFR2 signaling	R-HSA-5654727	1.780356e-02	1.749	0	0
Dual Incision in GG-NER	R-HSA-5696400	1.780356e-02	1.749	0	0
Autodegradation of the E3 ubiquitin ligase COP1	R-HSA-349425	1.780356e-02	1.749	0	0
Signaling by CSF1 (M-CSF) in myeloid cells	R-HSA-9680350	1.780356e-02	1.749	0	0
SPOP-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929491	1.787248e-02	1.748	0	0
Regulation of APC/C activators between G1/S and early anaphase	R-HSA-176408	1.805949e-02	1.743	0	0
MyD88 cascade initiated on plasma membrane	R-HSA-975871	1.831411e-02	1.737	0	0
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	1.831411e-02	1.737	0	0
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	1.831411e-02	1.737	0	0
NOTCH3 Activation and Transmission of Signal to the Nucleus	R-HSA-9013507	1.865627e-02	1.729	0	0
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	1.882496e-02	1.725	0	0
Regulation of TP53 Activity through Association with Co-factors	R-HSA-6804759	2.404644e-02	1.619	0	0
Signaling by cytosolic FGFR1 fusion mutants	R-HSA-1839117	2.366017e-02	1.626	0	0
IKK complex recruitment mediated by RIP1	R-HSA-937041	2.827933e-02	1.549	0	0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	R-HSA-9762114	2.638608e-02	1.579	0	0
APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176409	1.895769e-02	1.722	0	0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176814	2.108211e-02	1.676	0	0
Translesion Synthesis by POLH	R-HSA-110320	2.827933e-02	1.549	0	0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	R-HSA-9860927	2.039824e-02	1.690	0	0
Recognition of DNA damage by PCNA-containing replication complex	R-HSA-110314	2.583871e-02	1.588	0	0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	R-HSA-75035	2.404644e-02	1.619	1	1
Regulation of Apoptosis	R-HSA-169911	2.039824e-02	1.690	0	0
Developmental Cell Lineages	R-HSA-9734767	2.251171e-02	1.648	0	0
G1/S DNA Damage Checkpoints	R-HSA-69615	1.998093e-02	1.699	1	0
Activation of NF-kappaB in B cells	R-HSA-1169091	2.736675e-02	1.563	0	0
Signaling by FGFR4	R-HSA-5654743	2.566277e-02	1.591	0	0
Ion homeostasis	R-HSA-5578775	2.108211e-02	1.676	0	0
p53-Dependent G1/S DNA damage checkpoint	R-HSA-69580	2.206565e-02	1.656	0	0
p53-Dependent G1 DNA Damage Response	R-HSA-69563	2.206565e-02	1.656	0	0
Co-stimulation by CD28	R-HSA-389356	1.971728e-02	1.705	0	0
Degradation of GLI2 by the proteasome	R-HSA-5610783	2.024398e-02	1.694	0	0
GLI3 is processed to GLI3R by the proteasome	R-HSA-5610785	2.024398e-02	1.694	0	0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	R-HSA-975144	1.914744e-02	1.718	0	0
IRAK1 recruits IKK complex	R-HSA-937039	1.914744e-02	1.718	0	0
Intraflagellar transport	R-HSA-5620924	1.971728e-02	1.705	0	0
Negative regulation of MAPK pathway	R-HSA-5675221	2.024398e-02	1.694	0	0
Interleukin-6 signaling	R-HSA-1059683	2.404644e-02	1.619	0	0
PCP/CE pathway	R-HSA-4086400	1.934444e-02	1.713	0	0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence	R-HSA-9825895	2.151923e-02	1.667	0	0
Apoptotic cleavage of cell adhesion proteins	R-HSA-351906	2.151923e-02	1.667	0	0
Downregulation of ERBB4 signaling	R-HSA-1253288	2.151923e-02	1.667	0	0
FLT3 signaling in disease	R-HSA-9682385	2.325490e-02	1.633	0	0
Interleukin-3, Interleukin-5 and GM-CSF signaling	R-HSA-512988	2.283730e-02	1.641	0	0
Neurodegenerative Diseases	R-HSA-8863678	2.583871e-02	1.588	0	0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	R-HSA-8862803	2.583871e-02	1.588	0	0
p75NTR recruits signalling complexes	R-HSA-209543	1.914744e-02	1.718	0	0
Modulation by Mtb of host immune system	R-HSA-9637628	2.151923e-02	1.667	0	0
AKT phosphorylates targets in the nucleus	R-HSA-198693	2.834581e-02	1.548	0	0
ALK mutants bind TKIs	R-HSA-9700645	2.834581e-02	1.548	0	0
Unwinding of DNA	R-HSA-176974	2.834581e-02	1.548	0	0
SCF(Skp2)-mediated degradation of p27/p21	R-HSA-187577	2.873030e-02	1.542	0	0
Netrin-1 signaling	R-HSA-373752	2.873030e-02	1.542	0	0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes	R-HSA-9851695	2.896198e-02	1.538	0	0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	R-HSA-9841922	2.896198e-02	1.538	0	0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	R-HSA-9818564	2.896198e-02	1.538	0	0
Non-integrin membrane-ECM interactions	R-HSA-3000171	2.958694e-02	1.529	0	0
NRIF signals cell death from the nucleus	R-HSA-205043	2.968671e-02	1.527	0	0
RIPK1-mediated regulated necrosis	R-HSA-5213460	2.980368e-02	1.526	0	0
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	2.992632e-02	1.524	0	0
Long-term potentiation	R-HSA-9620244	3.005454e-02	1.522	0	0
SWI/SNF chromatin remodelers	R-HSA-9932451	3.005454e-02	1.522	0	0
ATP-dependent chromatin remodelers	R-HSA-9932444	3.005454e-02	1.522	0	0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)	R-HSA-9931269	3.033605e-02	1.518	0	0
Formation of RNA Pol II elongation complex	R-HSA-112382	3.033605e-02	1.518	0	0
Transcriptional regulation by RUNX3	R-HSA-8878159	3.152529e-02	1.501	0	0
Transcriptional Regulation by MECP2	R-HSA-8986944	3.192382e-02	1.496	0	0
Regulated Necrosis	R-HSA-5218859	3.195224e-02	1.495	0	0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A	R-HSA-69601	3.204936e-02	1.494	1	1
p53-Independent G1/S DNA Damage Checkpoint	R-HSA-69613	3.204936e-02	1.494	1	0
Signaling by FGFR3	R-HSA-5654741	3.204936e-02	1.494	0	0
Manipulation of host energy metabolism	R-HSA-9636667	3.337694e-02	1.477	0	0
Interactions of Tat with host cellular proteins	R-HSA-176034	3.337694e-02	1.477	0	0
Transcription of E2F targets under negative control by DREAM complex	R-HSA-1362277	3.345607e-02	1.476	0	0
Signal transduction by L1	R-HSA-445144	3.345607e-02	1.476	0	0
GSK3B-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929356	3.351883e-02	1.475	0	0
Stabilization of p53	R-HSA-69541	3.351883e-02	1.475	0	0
RNA Polymerase II Transcription Elongation	R-HSA-75955	3.352834e-02	1.475	0	0
Signaling by FGFR	R-HSA-190236	3.389143e-02	1.470	0	0
Regulation of TP53 Activity through Acetylation	R-HSA-6804758	3.452612e-02	1.462	0	0
Myogenesis	R-HSA-525793	3.471004e-02	1.460	0	0
KEAP1-NFE2L2 pathway	R-HSA-9755511	3.554914e-02	1.449	0	0
Formation of TC-NER Pre-Incision Complex	R-HSA-6781823	3.562882e-02	1.448	0	0
Formation of the embryonic stem cell BAF (esBAF) complex	R-HSA-9933946	3.609608e-02	1.443	0	0
DCC mediated attractive signaling	R-HSA-418885	3.609608e-02	1.443	0	0
Signaling by Leptin	R-HSA-2586552	3.632185e-02	1.440	0	0
Pexophagy	R-HSA-9664873	3.632185e-02	1.440	0	0
p75 NTR receptor-mediated signalling	R-HSA-193704	3.638542e-02	1.439	0	0
Regulation of RUNX3 expression and activity	R-HSA-8941858	3.754185e-02	1.425	0	0
Formation of Incision Complex in GG-NER	R-HSA-5696395	3.754185e-02	1.425	0	0
Negative regulation of NOTCH4 signaling	R-HSA-9604323	3.754185e-02	1.425	0	0
Generation of second messenger molecules	R-HSA-202433	3.754185e-02	1.425	0	0
Interleukin-1 family signaling	R-HSA-446652	3.758868e-02	1.425	0	0
Synthesis of DNA	R-HSA-69239	3.809304e-02	1.419	0	0
Vpu mediated degradation of CD4	R-HSA-180534	3.905737e-02	1.408	0	0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	R-HSA-450321	3.920955e-02	1.407	0	0
TAK1-dependent IKK and NF-kappa-B activation	R-HSA-445989	3.947698e-02	1.404	0	0
EPHA-mediated growth cone collapse	R-HSA-3928663	3.982007e-02	1.400	0	0
Regulation of TP53 Activity through Phosphorylation	R-HSA-6804756	4.050619e-02	1.392	1	1
Signaling by NOTCH3	R-HSA-9012852	4.061089e-02	1.391	0	0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	4.070009e-02	1.390	0	0
PKA-mediated phosphorylation of key metabolic factors	R-HSA-163358	4.134951e-02	1.384	0	0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	R-HSA-446388	4.134951e-02	1.384	0	0
NIK-->noncanonical NF-kB signaling	R-HSA-5676590	4.188214e-02	1.378	0	0
Hh mutants are degraded by ERAD	R-HSA-5362768	4.188214e-02	1.378	0	0
M-decay: degradation of maternal mRNAs by maternally stored factors	R-HSA-9820841	4.188214e-02	1.378	0	0
MyD88 dependent cascade initiated on endosome	R-HSA-975155	4.343396e-02	1.362	0	0
Nuclear events stimulated by ALK signaling in cancer	R-HSA-9725371	4.360148e-02	1.360	0	0
Ubiquitin-dependent degradation of Cyclin D	R-HSA-75815	4.396931e-02	1.357	0	0
Signaling by FGFR1	R-HSA-5654736	4.451447e-02	1.351	0	0
Intrinsic Pathway for Apoptosis	R-HSA-109606	4.451447e-02	1.351	0	0
Sensory processing of sound by outer hair cells of the cochlea	R-HSA-9662361	4.451447e-02	1.351	0	0
Ion transport by P-type ATPases	R-HSA-936837	4.483546e-02	1.348	0	0
PECAM1 interactions	R-HSA-210990	4.546341e-02	1.342	0	0
Regulation of localization of FOXO transcription factors	R-HSA-9614399	4.546341e-02	1.342	0	0
Gap-filling DNA repair synthesis and ligation in GG-NER	R-HSA-5696397	4.555503e-02	1.341	0	0
Inactivation of CSF3 (G-CSF) signaling	R-HSA-9705462	4.555503e-02	1.341	0	0
Signaling by PDGFR in disease	R-HSA-9671555	4.555503e-02	1.341	0	0
Initiation of Nuclear Envelope (NE) Reformation	R-HSA-2995383	4.555503e-02	1.341	0	0
Degradation of CDH1	R-HSA-9766229	4.800924e-02	1.319	0	0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	R-HSA-8854050	4.927123e-02	1.307	0	0
SCF-beta-TrCP mediated degradation of Emi1	R-HSA-174113	4.927123e-02	1.307	0	0
Oncogene Induced Senescence	R-HSA-2559585	4.927123e-02	1.307	0	0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	R-HSA-8866910	5.129531e-02	1.290	0	0
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	5.145162e-02	1.289	0	0
Signaling by CSF3 (G-CSF)	R-HSA-9674555	5.145162e-02	1.289	0	0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells	R-HSA-9927418	5.154716e-02	1.288	0	0
RNA Polymerase II Pre-transcription Events	R-HSA-674695	5.228094e-02	1.282	0	0
Signaling by NOTCH4	R-HSA-9013694	5.228094e-02	1.282	0	0
FGFR2 alternative splicing	R-HSA-6803529	5.250372e-02	1.280	0	0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	R-HSA-6804115	5.250372e-02	1.280	0	0
Downregulation of TGF-beta receptor signaling	R-HSA-2173788	5.250372e-02	1.280	0	0
Dual incision in TC-NER	R-HSA-6782135	5.307569e-02	1.275	0	0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	R-HSA-166058	5.369743e-02	1.270	0	0
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	5.369743e-02	1.270	0	0
Downstream TCR signaling	R-HSA-202424	5.389208e-02	1.268	0	0
Vesicle-mediated transport	R-HSA-5653656	5.390982e-02	1.268	0	0
Vif-mediated degradation of APOBEC3G	R-HSA-180585	5.497085e-02	1.260	0	0
Regulation of NFE2L2 gene expression	R-HSA-9818749	5.501571e-02	1.260	0	0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	R-HSA-8869496	5.501571e-02	1.260	0	0
RUNX3 regulates YAP1-mediated transcription	R-HSA-8951671	5.501571e-02	1.260	0	0
Nef and signal transduction	R-HSA-164944	5.501571e-02	1.260	0	0
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	5.569181e-02	1.254	0	0
Integration of provirus	R-HSA-162592	5.576948e-02	1.254	0	0
Reduction of cytosolic Ca++ levels	R-HSA-418359	5.576948e-02	1.254	0	0
Activation of RAC1	R-HSA-428540	5.576948e-02	1.254	0	0
Regulation of TP53 Expression	R-HSA-6804754	5.581386e-02	1.253	0	0
TGFBR1 LBD Mutants in Cancer	R-HSA-3656535	5.581386e-02	1.253	0	0
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	R-HSA-6781827	5.637106e-02	1.249	0	0
Hh mutants abrogate ligand secretion	R-HSA-5387390	5.688557e-02	1.245	0	0
Signaling by SCF-KIT	R-HSA-1433557	5.688557e-02	1.245	1	1
Nucleotide Excision Repair	R-HSA-5696398	5.769174e-02	1.239	0	0
Hedgehog ligand biogenesis	R-HSA-5358346	5.769840e-02	1.239	0	0
Signaling by ERBB2 in Cancer	R-HSA-1227990	5.799112e-02	1.237	0	0
SHC1 events in ERBB2 signaling	R-HSA-1250196	5.799112e-02	1.237	0	0
Activation of the pre-replicative complex	R-HSA-68962	5.799112e-02	1.237	0	0
Activation of BH3-only proteins	R-HSA-114452	5.799112e-02	1.237	0	0
Global Genome Nucleotide Excision Repair (GG-NER)	R-HSA-5696399	5.925102e-02	1.227	0	0
Cellular response to chemical stress	R-HSA-9711123	5.981162e-02	1.223	0	0
Syndecan interactions	R-HSA-3000170	6.006279e-02	1.221	0	0
Glycogen storage diseases	R-HSA-3229121	6.010272e-02	1.221	0	0
Nuclear events mediated by NFE2L2	R-HSA-9759194	6.023781e-02	1.220	0	0
Degradation of DVL	R-HSA-4641258	6.107427e-02	1.214	0	0
Degradation of AXIN	R-HSA-4641257	6.107427e-02	1.214	0	0
Beta-catenin independent WNT signaling	R-HSA-3858494	6.184745e-02	1.209	0	0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	R-HSA-8864260	6.256850e-02	1.204	0	0
SARS-CoV-1 activates/modulates innate immune responses	R-HSA-9692916	6.298971e-02	1.201	0	0
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	6.370680e-02	1.196	0	0
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	6.370680e-02	1.196	0	0
Budding and maturation of HIV virion	R-HSA-162588	6.502098e-02	1.187	0	0
Evasion by RSV of host interferon responses	R-HSA-9833109	6.502098e-02	1.187	0	0
Formation of the dystrophin-glycoprotein complex (DGC)	R-HSA-9913351	6.502098e-02	1.187	0	0
Disease	R-HSA-1643685	6.606056e-02	1.180	0	0
TP53 Regulates Metabolic Genes	R-HSA-5628897	6.634084e-02	1.178	0	0
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	6.634084e-02	1.178	0	0
AKT phosphorylates targets in the cytosol	R-HSA-198323	6.722355e-02	1.172	0	0
Constitutive Signaling by Overexpressed ERBB2	R-HSA-9634285	6.722355e-02	1.172	0	0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	R-HSA-9820865	6.722355e-02	1.172	0	0
Constitutive Signaling by NOTCH1 HD Domain Mutants	R-HSA-2691232	6.722355e-02	1.172	0	0
Signaling by NOTCH1 HD Domain Mutants in Cancer	R-HSA-2691230	6.722355e-02	1.172	0	0
MET promotes cell motility	R-HSA-8875878	6.758593e-02	1.170	0	0
Deadenylation of mRNA	R-HSA-429947	6.823535e-02	1.166	0	0
Dectin-1 mediated noncanonical NF-kB signaling	R-HSA-5607761	6.859992e-02	1.164	0	0
Asymmetric localization of PCP proteins	R-HSA-4608870	6.859992e-02	1.164	0	0
Defective CFTR causes cystic fibrosis	R-HSA-5678895	6.859992e-02	1.164	0	0
Signaling by ERBB2 ECD mutants	R-HSA-9665348	6.971476e-02	1.157	0	0
Polo-like kinase mediated events	R-HSA-156711	6.971476e-02	1.157	0	0
Platelet sensitization by LDL	R-HSA-432142	6.971476e-02	1.157	0	0
RUNX3 Regulates Immune Response and Cell Migration	R-HSA-8949275	7.054761e-02	1.152	0	0
SHOC2 M1731 mutant abolishes MRAS complex function	R-HSA-9726840	7.054761e-02	1.152	0	0
Activation of PUMA and translocation to mitochondria	R-HSA-139915	7.054761e-02	1.152	0	0
Uptake and function of diphtheria toxin	R-HSA-5336415	7.054761e-02	1.152	0	0
Displacement of DNA glycosylase by APEX1	R-HSA-110357	7.054761e-02	1.152	0	0
Degradation of beta-catenin by the destruction complex	R-HSA-195253	7.177170e-02	1.144	0	0
Cytosolic sensors of pathogen-associated DNA	R-HSA-1834949	7.177170e-02	1.144	0	0
ER to Golgi Anterograde Transport	R-HSA-199977	7.240773e-02	1.140	0	0
Diseases of mitotic cell cycle	R-HSA-9675126	7.254397e-02	1.139	0	0
G0 and Early G1	R-HSA-1538133	7.254397e-02	1.139	0	0
Interleukin-7 signaling	R-HSA-1266695	7.702050e-02	1.113	0	0
CREB1 phosphorylation through the activation of Adenylate Cyclase	R-HSA-442720	7.979529e-02	1.098	0	0
Frs2-mediated activation	R-HSA-170968	7.979529e-02	1.098	0	0
CD28 dependent Vav1 pathway	R-HSA-389359	7.979529e-02	1.098	0	0
Transmission across Chemical Synapses	R-HSA-112315	8.000957e-02	1.097	0	0
Rap1 signalling	R-HSA-392517	8.012230e-02	1.096	0	0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes	R-HSA-9856532	8.012230e-02	1.096	0	0
G-protein beta:gamma signalling	R-HSA-397795	8.056035e-02	1.094	0	0
MET activates STAT3	R-HSA-8875791	8.207382e-02	1.086	0	0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins	R-HSA-9673766	8.207382e-02	1.086	0	0
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	8.266502e-02	1.083	0	0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	8.509638e-02	1.070	0	0
Opioid Signalling	R-HSA-111885	8.541224e-02	1.068	0	0
APC truncation mutants are not K63 polyubiquitinated	R-HSA-5467333	9.024649e-02	1.045	0	0
Loss of function of TP53 in cancer due to loss of tetramerization ability	R-HSA-9723905	9.024649e-02	1.045	0	0
Defective translocation of RB1 mutants to the nucleus	R-HSA-9661070	9.024649e-02	1.045	0	0
Loss of Function of TP53 in Cancer	R-HSA-9723907	9.024649e-02	1.045	0	0
Drug-mediated inhibition of MET activation	R-HSA-9734091	1.723534e-01	0.764	0	0
Alternative Lengthening of Telomeres (ALT)	R-HSA-9006821	1.723534e-01	0.764	0	0
Defective Inhibition of DNA Recombination at Telomere	R-HSA-9670621	1.723534e-01	0.764	0	0
Diseases of Telomere Maintenance	R-HSA-9673013	1.723534e-01	0.764	0	0
Regulation of PAK-2p34 activity by PS-GAP/RHG10	R-HSA-211728	1.723534e-01	0.764	0	0
RPIA deficiency: failed conversion of RU5P to R5P	R-HSA-6791461	1.723534e-01	0.764	0	0
RPIA deficiency: failed conversion of R5P to RU5P	R-HSA-5659996	1.723534e-01	0.764	0	0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations	R-HSA-9670615	1.723534e-01	0.764	0	0
Defective Mismatch Repair Associated With MSH6	R-HSA-5632968	1.723534e-01	0.764	0	0
Defective Mismatch Repair Associated With MSH3	R-HSA-5632927	1.723534e-01	0.764	0	0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	R-HSA-9670613	1.723534e-01	0.764	0	0
PLCG1 events in ERBB2 signaling	R-HSA-1251932	1.112850e-01	0.954	0	0
AKT-mediated inactivation of FOXO1A	R-HSA-211163	1.112850e-01	0.954	0	0
GRB7 events in ERBB2 signaling	R-HSA-1306955	1.112850e-01	0.954	0	0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	R-HSA-69200	1.112850e-01	0.954	0	0
SMAC (DIABLO) binds to IAPs	R-HSA-111463	1.427015e-01	0.846	0	0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	R-HSA-111464	1.427015e-01	0.846	0	0
IRS activation	R-HSA-74713	1.427015e-01	0.846	0	0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	R-HSA-9673768	1.427015e-01	0.846	0	0
Loss of Function of TGFBR1 in Cancer	R-HSA-3656534	1.427015e-01	0.846	0	0
Loss of phosphorylation of MECP2 at T308	R-HSA-9022535	1.427015e-01	0.846	0	0
Type I hemidesmosome assembly	R-HSA-446107	8.781125e-02	1.056	0	0
Signaling by MRAS-complex mutants	R-HSA-9660537	8.781125e-02	1.056	0	0
Gain-of-function MRAS complexes activate RAF signaling	R-HSA-9726842	8.781125e-02	1.056	0	0
Activation of RAC1 downstream of NMDARs	R-HSA-9619229	1.066534e-01	0.972	0	0
Calcineurin activates NFAT	R-HSA-2025928	1.066534e-01	0.972	0	0
2-LTR circle formation	R-HSA-164843	1.269085e-01	0.897	0	0
Folding of actin by CCT/TriC	R-HSA-390450	1.269085e-01	0.897	0	0
ChREBP activates metabolic gene expression	R-HSA-163765	1.484047e-01	0.829	0	0
IRF3-mediated induction of type I IFN	R-HSA-3270619	1.081120e-01	0.966	0	0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	R-HSA-9934037	9.130978e-02	1.039	0	0
Translesion synthesis by POLI	R-HSA-5656121	1.237432e-01	0.907	0	0
Aberrant regulation of mitotic exit in cancer due to RB1 defects	R-HSA-9687136	1.237432e-01	0.907	0	0
NFE2L2 regulates pentose phosphate pathway genes	R-HSA-9818028	1.709683e-01	0.767	0	0
Sema4D mediated inhibition of cell attachment and migration	R-HSA-416550	1.709683e-01	0.767	0	0
APOBEC3G mediated resistance to HIV-1 infection	R-HSA-180689	1.709683e-01	0.767	0	0
PD-L1(CD274) glycosylation and translocation to plasma membrane	R-HSA-9931295	1.032557e-01	0.986	0	0
Processing of Intronless Pre-mRNAs	R-HSA-77595	1.402677e-01	0.853	0	0
Translesion synthesis by POLK	R-HSA-5655862	1.402677e-01	0.853	0	0
Inactivation of APC/C via direct inhibition of the APC/C complex	R-HSA-141430	1.402677e-01	0.853	0	0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	R-HSA-8866652	9.640587e-02	1.016	0	0
Constitutive Signaling by EGFRvIII	R-HSA-5637810	1.576123e-01	0.802	0	0
Signaling by EGFRvIII in Cancer	R-HSA-5637812	1.576123e-01	0.802	0	0
PI3K events in ERBB2 signaling	R-HSA-1963642	1.576123e-01	0.802	0	0
Developmental Lineage of Mammary Stem Cells	R-HSA-9938206	1.293103e-01	0.888	0	0
HIV elongation arrest and recovery	R-HSA-167287	1.069856e-01	0.971	0	0
Pausing and recovery of HIV elongation	R-HSA-167290	1.069856e-01	0.971	0	0
Signaling by ERBB2 KD Mutants	R-HSA-9664565	1.181373e-01	0.928	0	0
Endosomal Sorting Complex Required For Transport (ESCRT)	R-HSA-917729	1.181373e-01	0.928	0	0
Aberrant regulation of mitotic cell cycle due to RB1 defects	R-HSA-9687139	1.298426e-01	0.887	0	0
Signaling by ERBB2 TMD/JMD mutants	R-HSA-9665686	1.580168e-01	0.801	0	0
Gap-filling DNA repair synthesis and ligation in TC-NER	R-HSA-6782210	8.720850e-02	1.059	0	0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	R-HSA-9725554	1.500131e-01	0.824	0	0
Early Phase of HIV Life Cycle	R-HSA-162594	1.032557e-01	0.986	0	0
CD28 dependent PI3K/Akt signaling	R-HSA-389357	9.640587e-02	1.016	0	0
Golgi Associated Vesicle Biogenesis	R-HSA-432722	1.294762e-01	0.888	0	0
DNA Damage Bypass	R-HSA-73893	9.624801e-02	1.017	0	0
Translesion synthesis by REV1	R-HSA-110312	1.081120e-01	0.966	0	0
Regulation of IFNA/IFNB signaling	R-HSA-912694	1.293103e-01	0.888	0	0
DNA strand elongation	R-HSA-69190	1.548265e-01	0.810	0	0
RUNX1 regulates transcription of genes involved in BCR signaling	R-HSA-8939245	1.427015e-01	0.846	0	0
Inactivation of CDC42 and RAC1	R-HSA-428543	1.066534e-01	0.972	0	0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	R-HSA-9634600	1.237432e-01	0.907	0	0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	R-HSA-9634638	1.433514e-01	0.844	0	0
Retrograde transport at the Trans-Golgi-Network	R-HSA-6811440	1.549373e-01	0.810	0	0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	R-HSA-6803205	1.293103e-01	0.888	0	0
G1 Phase	R-HSA-69236	1.246176e-01	0.904	0	0
Cyclin D associated events in G1	R-HSA-69231	1.246176e-01	0.904	0	0
TP53 Regulates Transcription of Cell Cycle Genes	R-HSA-6791312	9.403374e-02	1.027	0	0
Signaling by FGFR1 in disease	R-HSA-5655302	9.774470e-02	1.010	0	0
Prolonged ERK activation events	R-HSA-169893	1.237432e-01	0.907	0	0
trans-Golgi Network Vesicle Budding	R-HSA-199992	1.429824e-01	0.845	0	0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	R-HSA-9856530	1.360384e-01	0.866	0	0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	R-HSA-141405	1.402677e-01	0.853	0	0
Degradation of CRY and PER proteins	R-HSA-9932298	9.774470e-02	1.010	0	0
RNA Polymerase I Transcription Initiation	R-HSA-73762	1.063051e-01	0.973	0	0
Platelet calcium homeostasis	R-HSA-418360	1.181373e-01	0.928	0	0
Activation of BAD and translocation to mitochondria	R-HSA-111447	1.081120e-01	0.966	0	0
Metabolism of nitric oxide: NOS3 activation and regulation	R-HSA-202131	1.387331e-01	0.858	0	0
Interleukin-1 signaling	R-HSA-9020702	1.172390e-01	0.931	0	0
PTK6 Regulates Proteins Involved in RNA Processing	R-HSA-8849468	1.427015e-01	0.846	0	0
ROBO receptors bind AKAP5	R-HSA-9010642	8.781125e-02	1.056	0	0
FGFR1 mutant receptor activation	R-HSA-1839124	1.680552e-01	0.775	0	0
Glycogen synthesis	R-HSA-3322077	9.130978e-02	1.039	0	0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	R-HSA-6804114	1.402677e-01	0.853	0	0
CLEC7A (Dectin-1) signaling	R-HSA-5607764	8.914755e-02	1.050	0	0
Signalling to ERKs	R-HSA-187687	1.075360e-01	0.968	0	0
Toll-like Receptor Cascades	R-HSA-168898	1.476881e-01	0.831	0	0
Formation of editosomes by ADAR proteins	R-HSA-77042	1.723534e-01	0.764	0	0
Inhibition of PKR	R-HSA-169131	1.723534e-01	0.764	0	0
MTF1 activates gene expression	R-HSA-5660489	1.112850e-01	0.954	0	0
Basigin interactions	R-HSA-210991	1.032557e-01	0.986	0	0
Regulation of FZD by ubiquitination	R-HSA-4641263	1.576123e-01	0.802	0	0
Transcriptional Regulation by VENTX	R-HSA-8853884	8.958945e-02	1.048	0	0
C-type lectin receptors (CLRs)	R-HSA-5621481	1.419024e-01	0.848	0	0
ER-Phagosome pathway	R-HSA-1236974	8.755775e-02	1.058	0	0
NOD1/2 Signaling Pathway	R-HSA-168638	9.806212e-02	1.008	0	0
HuR (ELAVL1) binds and stabilizes mRNA	R-HSA-450520	1.066534e-01	0.972	0	0
Activated NOTCH1 Transmits Signal to the Nucleus	R-HSA-2122948	8.641350e-02	1.063	0	0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	R-HSA-8939243	1.680552e-01	0.775	0	0
Antigen processing-Cross presentation	R-HSA-1236975	1.116113e-01	0.952	0	0
Glycogen metabolism	R-HSA-8982491	1.617068e-01	0.791	0	0
Regulation of pyruvate metabolism	R-HSA-9861718	1.444644e-01	0.840	0	0
Gluconeogenesis	R-HSA-70263	8.880693e-02	1.052	0	0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	R-HSA-9825892	1.159331e-01	0.936	0	0
Regulation of RUNX2 expression and activity	R-HSA-8939902	1.243912e-01	0.905	0	0
NOTCH2 Activation and Transmission of Signal to the Nucleus	R-HSA-2979096	1.032557e-01	0.986	0	0
Signal regulatory protein family interactions	R-HSA-391160	9.344234e-02	1.029	0	0
Sensory processing of sound by inner hair cells of the cochlea	R-HSA-9662360	1.118893e-01	0.951	0	0
NRAGE signals death through JNK	R-HSA-193648	1.578791e-01	0.802	0	0
Hedgehog 'on' state	R-HSA-5632684	1.348167e-01	0.870	0	0
Interleukin-6 family signaling	R-HSA-6783589	1.580168e-01	0.801	0	0
Co-inhibition by BTLA	R-HSA-9927353	1.427015e-01	0.846	0	0
Butyrophilin (BTN) family interactions	R-HSA-8851680	1.066534e-01	0.972	0	0
Detoxification of Reactive Oxygen Species	R-HSA-3299685	1.578791e-01	0.802	0	0
Sensory processing of sound	R-HSA-9659379	1.285204e-01	0.891	0	0
Plasma lipoprotein clearance	R-HSA-8964043	1.500131e-01	0.824	0	0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	R-HSA-975110	1.402677e-01	0.853	0	0
Response of Mtb to phagocytosis	R-HSA-9637690	1.152651e-01	0.938	0	0
Growth hormone receptor signaling	R-HSA-982772	1.433514e-01	0.844	0	0
Regulation of BACH1 activity	R-HSA-9708530	1.237432e-01	0.907	0	0
HDMs demethylate histones	R-HSA-3214842	1.732639e-01	0.761	0	0
Tight junction interactions	R-HSA-420029	1.732639e-01	0.761	0	0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	1.737958e-01	0.760	0	0
SMAC, XIAP-regulated apoptotic response	R-HSA-111469	1.756882e-01	0.755	0	0
RUNX3 regulates CDKN1A transcription	R-HSA-8941855	1.756882e-01	0.755	0	0
PTK6 Regulates Cell Cycle	R-HSA-8849470	1.756882e-01	0.755	0	0
Noncanonical activation of NOTCH3	R-HSA-9017802	1.756882e-01	0.755	0	0
Activation of caspases through apoptosome-mediated cleavage	R-HSA-111459	1.756882e-01	0.755	0	0
IkBA variant leads to EDA-ID	R-HSA-5603029	1.756882e-01	0.755	0	0
Negative feedback regulation of MAPK pathway	R-HSA-5674499	1.756882e-01	0.755	0	0
Sodium-coupled phosphate cotransporters	R-HSA-427652	1.756882e-01	0.755	0	0
GAB1 signalosome	R-HSA-180292	1.756995e-01	0.755	0	0
ZBP1(DAI) mediated induction of type I IFNs	R-HSA-1606322	1.756995e-01	0.755	0	0
NOTCH1 Intracellular Domain Regulates Transcription	R-HSA-2122947	1.769191e-01	0.752	0	0
Association of TriC/CCT with target proteins during biosynthesis	R-HSA-390471	1.817383e-01	0.741	0	0
Regulation of PD-L1(CD274) Post-translational modification	R-HSA-9909615	1.859038e-01	0.731	0	0
MECP2 regulates neuronal receptors and channels	R-HSA-9022699	1.890477e-01	0.723	0	0
Ion channel transport	R-HSA-983712	1.897694e-01	0.722	0	0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	R-HSA-9027276	1.944276e-01	0.711	0	0
Regulation of IFNG signaling	R-HSA-877312	1.944276e-01	0.711	0	0
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	1.944496e-01	0.711	0	0
The NLRP3 inflammasome	R-HSA-844456	1.944496e-01	0.711	0	0
STING mediated induction of host immune responses	R-HSA-1834941	1.944496e-01	0.711	0	0
eNOS activation	R-HSA-203615	1.958461e-01	0.708	0	0
Signaling by NOTCH2	R-HSA-1980145	1.958461e-01	0.708	0	0
G alpha (12/13) signalling events	R-HSA-416482	1.970971e-01	0.705	0	0
Developmental Lineage of Pancreatic Ductal Cells	R-HSA-9925563	1.988222e-01	0.702	0	0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	R-HSA-1234176	2.001855e-01	0.699	0	0
Inositol phosphate metabolism	R-HSA-1483249	2.031614e-01	0.692	0	0
Pyruvate metabolism	R-HSA-70268	2.042094e-01	0.690	0	0
Tat-mediated HIV elongation arrest and recovery	R-HSA-167243	2.053212e-01	0.688	0	0
Pausing and recovery of Tat-mediated HIV elongation	R-HSA-167238	2.053212e-01	0.688	0	0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	R-HSA-6803204	2.053212e-01	0.688	0	0
Interleukin-4 and Interleukin-13 signaling	R-HSA-6785807	2.082431e-01	0.681	0	0
Autointegration results in viral DNA circles	R-HSA-177539	2.097061e-01	0.678	0	0
RAS signaling downstream of NF1 loss-of-function variants	R-HSA-6802953	2.097061e-01	0.678	0	0
Signaling by TGF-beta Receptor Complex in Cancer	R-HSA-3304351	2.097061e-01	0.678	0	0
Activation of NIMA Kinases NEK9, NEK6, NEK7	R-HSA-2980767	2.097061e-01	0.678	0	0
Integration of viral DNA into host genomic DNA	R-HSA-175567	2.097061e-01	0.678	0	0
Co-inhibition by CTLA4	R-HSA-389513	2.137814e-01	0.670	0	0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	R-HSA-9659787	2.186151e-01	0.660	0	0
Formation of the non-canonical BAF (ncBAF) complex	R-HSA-9933947	2.186151e-01	0.660	0	0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	R-HSA-9661069	2.186151e-01	0.660	0	0
Negative regulation of the PI3K/AKT network	R-HSA-199418	2.189865e-01	0.660	0	0
Phase 0 - rapid depolarisation	R-HSA-5576892	2.220360e-01	0.654	0	0
PINK1-PRKN Mediated Mitophagy	R-HSA-5205685	2.220360e-01	0.654	0	0
Hemostasis	R-HSA-109582	2.247734e-01	0.648	0	0
PKA-mediated phosphorylation of CREB	R-HSA-111931	2.336134e-01	0.632	0	0
ERK/MAPK targets	R-HSA-198753	2.336134e-01	0.632	0	0
Prevention of phagosomal-lysosomal fusion	R-HSA-9636383	2.336134e-01	0.632	0	0
rRNA modification in the nucleus and cytosol	R-HSA-6790901	2.342355e-01	0.630	0	0
Termination of translesion DNA synthesis	R-HSA-5656169	2.391430e-01	0.621	0	0
Retrograde neurotrophin signalling	R-HSA-177504	2.433706e-01	0.614	0	0
ERBB2 Activates PTK6 Signaling	R-HSA-8847993	2.433706e-01	0.614	0	0
TP53 Regulates Transcription of Death Receptors and Ligands	R-HSA-6803211	2.433706e-01	0.614	0	0
Formation of the canonical BAF (cBAF) complex	R-HSA-9933937	2.433706e-01	0.614	0	0
Regulation of KIT signaling	R-HSA-1433559	2.433706e-01	0.614	0	0
RUNX3 regulates WNT signaling	R-HSA-8951430	2.443009e-01	0.612	0	0
MET activates PI3K/AKT signaling	R-HSA-8851907	2.443009e-01	0.612	0	0
PP2A-mediated dephosphorylation of key metabolic factors	R-HSA-163767	2.443009e-01	0.612	0	0
NOSTRIN mediated eNOS trafficking	R-HSA-203641	2.443009e-01	0.612	0	0
Binding of TCF/LEF:CTNNB1 to target gene promoters	R-HSA-4411364	2.443009e-01	0.612	0	0
SOS-mediated signalling	R-HSA-112412	2.443009e-01	0.612	0	0
CHL1 interactions	R-HSA-447041	2.443009e-01	0.612	0	0
TGFBR3 regulates TGF-beta signaling	R-HSA-9839389	2.443009e-01	0.612	0	0
MECP2 regulates transcription factors	R-HSA-9022707	2.443009e-01	0.612	0	0
Interferon alpha/beta signaling	R-HSA-909733	2.457492e-01	0.610	0	0
Defective Mismatch Repair Associated With MSH2	R-HSA-5632928	2.470545e-01	0.607	0	0
PTEN Loss of Function in Cancer	R-HSA-5674404	2.470545e-01	0.607	0	0
IKBKB deficiency causes SCID	R-HSA-5602636	2.470545e-01	0.607	0	0
Defective SLC6A2 causes orthostatic intolerance (OI)	R-HSA-5619109	2.470545e-01	0.607	0	0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	R-HSA-5603027	2.470545e-01	0.607	0	0
Signaling by TCF7L2 mutants	R-HSA-5339700	2.470545e-01	0.607	0	0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1)	R-HSA-5619111	2.470545e-01	0.607	0	0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)	R-HSA-5619054	2.470545e-01	0.607	0	0
TGFBR3 regulates FGF2 signaling	R-HSA-9839397	2.470545e-01	0.607	0	0
Transport of connexins along the secretory pathway	R-HSA-190827	2.470545e-01	0.607	0	0
Oligomerization of connexins into connexons	R-HSA-190704	2.470545e-01	0.607	0	0
Breakdown of the nuclear lamina	R-HSA-352238	2.470545e-01	0.607	0	0
Potential therapeutics for SARS	R-HSA-9679191	2.476112e-01	0.606	0	0
Stimuli-sensing channels	R-HSA-2672351	2.514353e-01	0.600	0	0
Signaling by FGFR in disease	R-HSA-1226099	2.531525e-01	0.597	0	0
Signaling by ERBB4	R-HSA-1236394	2.531525e-01	0.597	0	0
mRNA Splicing - Minor Pathway	R-HSA-72165	2.534366e-01	0.596	0	0
Extra-nuclear estrogen signaling	R-HSA-9009391	2.671651e-01	0.573	0	0
STAT3 nuclear events downstream of ALK signaling	R-HSA-9701898	2.685421e-01	0.571	0	0
RIP-mediated NFkB activation via ZBP1	R-HSA-1810476	2.685421e-01	0.571	0	0
ERBB2 Regulates Cell Motility	R-HSA-6785631	2.685421e-01	0.571	0	0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	R-HSA-450385	2.685421e-01	0.571	0	0
p38MAPK events	R-HSA-171007	2.685421e-01	0.571	0	0
Signaling by ALK	R-HSA-201556	2.716294e-01	0.566	0	0
RAS processing	R-HSA-9648002	2.716294e-01	0.566	0	0
Negative regulators of DDX58/IFIH1 signaling	R-HSA-936440	2.743348e-01	0.562	0	0
Signaling by NOTCH1	R-HSA-1980143	2.761862e-01	0.559	0	0
RSK activation	R-HSA-444257	2.790917e-01	0.554	0	0
Formyl peptide receptors bind formyl peptides and many other ligands	R-HSA-444473	2.790917e-01	0.554	0	0
MET receptor recycling	R-HSA-8875656	2.790917e-01	0.554	0	0
Interleukin-23 signaling	R-HSA-9020933	2.790917e-01	0.554	0	0
Interleukin-9 signaling	R-HSA-8985947	2.790917e-01	0.554	0	0
Transcriptional regulation by RUNX2	R-HSA-8878166	2.820988e-01	0.550	0	0
NGF-stimulated transcription	R-HSA-9031628	2.821253e-01	0.550	0	0
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	2.843301e-01	0.546	0	0
Formation of HIV elongation complex in the absence of HIV Tat	R-HSA-167152	2.875994e-01	0.541	0	0
KSRP (KHSRP) binds and destabilizes mRNA	R-HSA-450604	2.939869e-01	0.532	0	0
Phosphorylation of the APC/C	R-HSA-176412	2.939869e-01	0.532	0	0
GRB2:SOS provides linkage to MAPK signaling for Integrins	R-HSA-354194	2.939869e-01	0.532	0	0
WNT5A-dependent internalization of FZD4	R-HSA-5099900	2.939869e-01	0.532	0	0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	R-HSA-6804116	2.939869e-01	0.532	0	0
Receptor-type tyrosine-protein phosphatases	R-HSA-388844	2.939869e-01	0.532	0	0
G beta:gamma signalling through PI3Kgamma	R-HSA-392451	2.953095e-01	0.530	0	0
Interleukin-20 family signaling	R-HSA-8854691	2.953095e-01	0.530	0	0
The role of Nef in HIV-1 replication and disease pathogenesis	R-HSA-164952	2.953095e-01	0.530	0	0
Resolution of Abasic Sites (AP sites)	R-HSA-73933	3.037608e-01	0.517	0	0
Neuronal System	R-HSA-112316	3.073864e-01	0.512	0	0
Integrin signaling	R-HSA-354192	3.105014e-01	0.508	0	0
Cyclin A/B1/B2 associated events during G2/M transition	R-HSA-69273	3.105014e-01	0.508	0	0
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	3.125482e-01	0.505	0	0
Lipophagy	R-HSA-9613354	3.137616e-01	0.503	0	0
5-Phosphoribose 1-diphosphate biosynthesis	R-HSA-73843	3.137616e-01	0.503	0	0
AMPK inhibits chREBP transcriptional activation activity	R-HSA-163680	3.137616e-01	0.503	0	0
Interleukin-21 signaling	R-HSA-9020958	3.137616e-01	0.503	0	0
Regulated proteolysis of p75NTR	R-HSA-193692	3.137616e-01	0.503	0	0
GP1b-IX-V activation signalling	R-HSA-430116	3.137616e-01	0.503	0	0
Zinc influx into cells by the SLC39 gene family	R-HSA-442380	3.137616e-01	0.503	0	0
ARMS-mediated activation	R-HSA-170984	3.137616e-01	0.503	0	0
Respiratory syncytial virus genome replication	R-HSA-9834752	3.137616e-01	0.503	0	0
Stimulation of the cell death response by PAK-2p34	R-HSA-211736	3.150172e-01	0.502	0	0
RUNX3 regulates RUNX1-mediated transcription	R-HSA-8951911	3.150172e-01	0.502	0	0
Defective AHCY causes HMAHCHD	R-HSA-5578997	3.150172e-01	0.502	0	0
TGFBR2 Kinase Domain Mutants in Cancer	R-HSA-3645790	3.150172e-01	0.502	0	0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3)	R-HSA-5619089	3.150172e-01	0.502	0	0
Glycogen storage disease type 0 (muscle GYS1)	R-HSA-3828062	3.150172e-01	0.502	0	0
Glycogen storage disease type XV (GYG1)	R-HSA-3814836	3.150172e-01	0.502	0	0
Potassium transport channels	R-HSA-1296067	3.150172e-01	0.502	0	0
mRNA Editing: A to I Conversion	R-HSA-75064	3.150172e-01	0.502	0	0
C6 deamination of adenosine	R-HSA-75102	3.150172e-01	0.502	0	0
Loss of Function of TGFBR2 in Cancer	R-HSA-3642278	3.150172e-01	0.502	0	0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	R-HSA-446343	3.150172e-01	0.502	0	0
Activation, myristolyation of BID and translocation to mitochondria	R-HSA-75108	3.150172e-01	0.502	0	0
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	3.163509e-01	0.500	0	0
Signaling by NOTCH1 PEST Domain Mutants in Cancer	R-HSA-2644602	3.170554e-01	0.499	0	0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	R-HSA-2894862	3.170554e-01	0.499	0	0
Constitutive Signaling by NOTCH1 PEST Domain Mutants	R-HSA-2644606	3.170554e-01	0.499	0	0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	R-HSA-2894858	3.170554e-01	0.499	0	0
Signaling by NOTCH1 in Cancer	R-HSA-2644603	3.170554e-01	0.499	0	0
G beta:gamma signalling through CDC42	R-HSA-8964616	3.195728e-01	0.495	0	0
Antigen processing: Ub, ATP-independent proteasomal degradation	R-HSA-9912633	3.195728e-01	0.495	0	0
Acetylcholine regulates insulin secretion	R-HSA-399997	3.195728e-01	0.495	0	0
NFE2L2 regulating anti-oxidant/detoxification enzymes	R-HSA-9818027	3.288297e-01	0.483	0	0
Miscellaneous transport and binding events	R-HSA-5223345	3.288297e-01	0.483	0	0
VEGFR2 mediated cell proliferation	R-HSA-5218921	3.375086e-01	0.472	0	0
p130Cas linkage to MAPK signaling for integrins	R-HSA-372708	3.451781e-01	0.462	0	0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	R-HSA-176407	3.451781e-01	0.462	0	0
Calnexin/calreticulin cycle	R-HSA-901042	3.472591e-01	0.459	0	0
Mitophagy	R-HSA-5205647	3.472591e-01	0.459	0	0
Binding and entry of HIV virion	R-HSA-173107	3.480492e-01	0.458	0	0
Cross-presentation of particulate exogenous antigens (phagosomes)	R-HSA-1236973	3.480492e-01	0.458	0	0
EGFR Transactivation by Gastrin	R-HSA-2179392	3.480492e-01	0.458	0	0
Formation of apoptosome	R-HSA-111458	3.480492e-01	0.458	0	0
Regulation of CDH11 function	R-HSA-9762292	3.480492e-01	0.458	0	0
PI3K/AKT activation	R-HSA-198203	3.480492e-01	0.458	0	0
Regulation of the apoptosome activity	R-HSA-9627069	3.480492e-01	0.458	0	0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	R-HSA-5140745	3.480492e-01	0.458	0	0
Signal attenuation	R-HSA-74749	3.480492e-01	0.458	0	0
Positive Regulation of CDH1 Gene Transcription	R-HSA-9764790	3.480492e-01	0.458	0	0
Interleukin-27 signaling	R-HSA-9020956	3.480492e-01	0.458	0	0
Assembly and release of respiratory syncytial virus (RSV) virions	R-HSA-9820962	3.480492e-01	0.458	0	0
TRP channels	R-HSA-3295583	3.587146e-01	0.445	0	0
Suppression of phagosomal maturation	R-HSA-9637687	3.587146e-01	0.445	0	0
ABC-family proteins mediated transport	R-HSA-382556	3.608604e-01	0.443	0	0
Formation of WDR5-containing histone-modifying complexes	R-HSA-9772755	3.657450e-01	0.437	0	0
Proteasome assembly	R-HSA-9907900	3.696466e-01	0.432	0	0
Trafficking of GluR2-containing AMPA receptors	R-HSA-416993	3.706920e-01	0.431	0	0
PKA activation	R-HSA-163615	3.706920e-01	0.431	0	0
Signalling to STAT3	R-HSA-198745	3.768492e-01	0.424	0	0
Diseases of Mismatch Repair (MMR)	R-HSA-5423599	3.768492e-01	0.424	0	0
Intracellular oxygen transport	R-HSA-8981607	3.768492e-01	0.424	0	0
Histamine receptors	R-HSA-390650	3.768492e-01	0.424	0	0
Interaction between L1 and Ankyrins	R-HSA-445095	3.799046e-01	0.420	0	0
Cristae formation	R-HSA-8949613	3.799046e-01	0.420	0	0
Signaling by NTRK2 (TRKB)	R-HSA-9006115	3.799046e-01	0.420	0	0
ER Quality Control Compartment (ERQC)	R-HSA-901032	3.799046e-01	0.420	0	0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	R-HSA-933543	3.817411e-01	0.418	0	0
Signaling by APC mutants	R-HSA-4839744	3.817411e-01	0.418	0	0
Truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	3.817411e-01	0.418	0	0
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	3.817411e-01	0.418	0	0
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	3.817411e-01	0.418	0	0
Suppression of apoptosis	R-HSA-9635465	3.817411e-01	0.418	0	0
G1/S-Specific Transcription	R-HSA-69205	3.842445e-01	0.415	0	0
Regulation of MITF-M-dependent genes involved in pigmentation	R-HSA-9824585	3.862657e-01	0.413	0	0
Cellular response to hypoxia	R-HSA-1234174	3.869883e-01	0.412	0	0
Respiratory Syncytial Virus Infection Pathway	R-HSA-9820952	3.872431e-01	0.412	0	0
PI-3K cascade:FGFR3	R-HSA-5654710	3.960141e-01	0.402	0	0
Inflammasomes	R-HSA-622312	4.010185e-01	0.397	0	0
Pyroptosis	R-HSA-5620971	4.010185e-01	0.397	0	0
Signaling by TGFBR3	R-HSA-9839373	4.028820e-01	0.395	0	0
Inactivation, recovery and regulation of the phototransduction cascade	R-HSA-2514859	4.028820e-01	0.395	0	0
DDX58/IFIH1-mediated induction of interferon-alpha/beta	R-HSA-168928	4.082693e-01	0.389	0	0
Inhibition of replication initiation of damaged DNA by RB1/E2F1	R-HSA-113501	4.146658e-01	0.382	0	0
Signaling by GSK3beta mutants	R-HSA-5339716	4.146658e-01	0.382	0	0
Cytochrome c-mediated apoptotic response	R-HSA-111461	4.146658e-01	0.382	0	0
Sensing of DNA Double Strand Breaks	R-HSA-5693548	4.146658e-01	0.382	0	0
Signaling by AMER1 mutants	R-HSA-4839748	4.146658e-01	0.382	0	0
Signaling by AXIN mutants	R-HSA-4839735	4.146658e-01	0.382	0	0
Sodium/Calcium exchangers	R-HSA-425561	4.146658e-01	0.382	0	0
ATF6 (ATF6-alpha) activates chaperone genes	R-HSA-381183	4.146658e-01	0.382	0	0
PI-3K cascade:FGFR4	R-HSA-5654720	4.210550e-01	0.376	0	0
Creatine metabolism	R-HSA-71288	4.210550e-01	0.376	0	0
Formation of definitive endoderm	R-HSA-9823730	4.210550e-01	0.376	0	0
Protein hydroxylation	R-HSA-9629569	4.210550e-01	0.376	0	0
Signaling by Erythropoietin	R-HSA-9006335	4.220001e-01	0.375	0	0
DARPP-32 events	R-HSA-180024	4.220001e-01	0.375	0	0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	R-HSA-6811558	4.222376e-01	0.374	0	0
MITF-M-dependent gene expression	R-HSA-9856651	4.229883e-01	0.374	0	0
tRNA processing	R-HSA-72306	4.260210e-01	0.371	0	0
ABC transporter disorders	R-HSA-5619084	4.261671e-01	0.370	0	0
Transcription of the HIV genome	R-HSA-167172	4.293380e-01	0.367	0	0
Regulation of gap junction activity	R-HSA-191650	4.331030e-01	0.363	0	0
TLR3-mediated TICAM1-dependent programmed cell death	R-HSA-9013957	4.331030e-01	0.363	0	0
NFE2L2 regulating ER-stress associated genes	R-HSA-9818035	4.331030e-01	0.363	0	0
RUNX3 regulates BCL2L11 (BIM) transcription	R-HSA-8952158	4.331030e-01	0.363	0	0
TGFBR1 KD Mutants in Cancer	R-HSA-3656532	4.331030e-01	0.363	0	0
Transcriptional activation of cell cycle inhibitor p21	R-HSA-69895	4.331030e-01	0.363	0	0
Transcriptional activation of p53 responsive genes	R-HSA-69560	4.331030e-01	0.363	0	0
SARS-CoV-1-mediated effects on programmed cell death	R-HSA-9692913	4.331030e-01	0.363	0	0
Activation of NOXA and translocation to mitochondria	R-HSA-111448	4.331030e-01	0.363	0	0
NADE modulates death signalling	R-HSA-205025	4.331030e-01	0.363	0	0
Regulation of HMOX1 expression and activity	R-HSA-9707587	4.331030e-01	0.363	0	0
SARS-CoV-2 targets PDZ proteins in cell-cell junction	R-HSA-9705677	4.331030e-01	0.363	0	0
Dopamine receptors	R-HSA-390651	4.331030e-01	0.363	0	0
Transport to the Golgi and subsequent modification	R-HSA-948021	4.337463e-01	0.363	0	0
Formation of HIV-1 elongation complex containing HIV-1 Tat	R-HSA-167200	4.394239e-01	0.357	0	0
Platelet homeostasis	R-HSA-418346	4.399297e-01	0.357	0	0
NOTCH3 Intracellular Domain Regulates Transcription	R-HSA-9013508	4.427978e-01	0.354	0	0
TNFR1-induced proapoptotic signaling	R-HSA-5357786	4.457350e-01	0.351	0	0
Signalling to RAS	R-HSA-167044	4.457350e-01	0.351	0	0
NOTCH4 Intracellular Domain Regulates Transcription	R-HSA-9013695	4.457350e-01	0.351	0	0
RUNX3 regulates p14-ARF	R-HSA-8951936	4.466873e-01	0.350	0	0
Repression of WNT target genes	R-HSA-4641265	4.466873e-01	0.350	0	0
RUNX3 regulates NOTCH signaling	R-HSA-8941856	4.466873e-01	0.350	0	0
Polymerase switching	R-HSA-69091	4.466873e-01	0.350	0	0
Leading Strand Synthesis	R-HSA-69109	4.466873e-01	0.350	0	0
Signaling by CTNNB1 phospho-site mutants	R-HSA-4839743	4.466873e-01	0.350	0	0
CTNNB1 S33 mutants aren't phosphorylated	R-HSA-5358747	4.466873e-01	0.350	0	0
CTNNB1 T41 mutants aren't phosphorylated	R-HSA-5358752	4.466873e-01	0.350	0	0
CTNNB1 S37 mutants aren't phosphorylated	R-HSA-5358749	4.466873e-01	0.350	0	0
CTNNB1 S45 mutants aren't phosphorylated	R-HSA-5358751	4.466873e-01	0.350	0	0
Advanced glycosylation endproduct receptor signaling	R-HSA-879415	4.466873e-01	0.350	0	0
Activated NTRK2 signals through FRS2 and FRS3	R-HSA-9028731	4.466873e-01	0.350	0	0
Interleukin-35 Signalling	R-HSA-8984722	4.466873e-01	0.350	0	0
Signaling by LTK	R-HSA-9842663	4.466873e-01	0.350	0	0
Erythrocytes take up oxygen and release carbon dioxide	R-HSA-1247673	4.466873e-01	0.350	0	0
Pervasive developmental disorders	R-HSA-9005895	4.466873e-01	0.350	0	0
Disorders of Nervous System Development	R-HSA-9697154	4.466873e-01	0.350	0	0
Loss of function of MECP2 in Rett syndrome	R-HSA-9005891	4.466873e-01	0.350	0	0
OAS antiviral response	R-HSA-8983711	4.466873e-01	0.350	0	0
MITF-M-regulated melanocyte development	R-HSA-9730414	4.467664e-01	0.350	0	0
Metabolism of proteins	R-HSA-392499	4.490644e-01	0.348	0	0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	R-HSA-532668	4.524289e-01	0.344	0	0
HIV Transcription Elongation	R-HSA-167169	4.575878e-01	0.340	0	0
Tat-mediated elongation of the HIV-1 transcript	R-HSA-167246	4.575878e-01	0.340	0	0
Transcriptional regulation of brown and beige adipocyte differentiation	R-HSA-9843743	4.575878e-01	0.340	0	0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	R-HSA-9844594	4.575878e-01	0.340	0	0
Molecules associated with elastic fibres	R-HSA-2129379	4.633640e-01	0.334	0	0
Downstream signal transduction	R-HSA-186763	4.633640e-01	0.334	0	0
PI3K Cascade	R-HSA-109704	4.687553e-01	0.329	0	0
Azathioprine ADME	R-HSA-9748787	4.687553e-01	0.329	0	0
Purine ribonucleoside monophosphate biosynthesis	R-HSA-73817	4.755812e-01	0.323	0	0
NFE2L2 regulating tumorigenic genes	R-HSA-9818030	4.777004e-01	0.321	0	0
PDH complex synthesizes acetyl-CoA from PYR	R-HSA-9861559	4.777004e-01	0.321	0	0
HDR through MMEJ (alt-NHEJ)	R-HSA-5685939	4.777004e-01	0.321	0	0
Golgi Cisternae Pericentriolar Stack Reorganization	R-HSA-162658	4.777004e-01	0.321	0	0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	R-HSA-9029558	4.777004e-01	0.321	0	0
Reversible hydration of carbon dioxide	R-HSA-1475029	4.777004e-01	0.321	0	0
ATF6 (ATF6-alpha) activates chaperones	R-HSA-381033	4.777004e-01	0.321	0	0
IRS-related events triggered by IGF1R	R-HSA-2428928	4.777327e-01	0.321	0	0
Regulation of ornithine decarboxylase (ODC)	R-HSA-350562	4.836553e-01	0.315	0	0
NFE2L2 regulating TCA cycle genes	R-HSA-9818025	4.842816e-01	0.315	0	0
NFE2L2 regulating inflammation associated genes	R-HSA-9818026	4.842816e-01	0.315	0	0
G2 Phase	R-HSA-68911	4.842816e-01	0.315	0	0
SMAD2/3 Phosphorylation Motif Mutants in Cancer	R-HSA-3304356	4.842816e-01	0.315	0	0
PTK6 Activates STAT3	R-HSA-8849474	4.842816e-01	0.315	0	0
Resolution of AP sites via the single-nucleotide replacement pathway	R-HSA-110381	4.842816e-01	0.315	0	0
IRF3 mediated activation of type 1 IFN	R-HSA-1606341	4.842816e-01	0.315	0	0
Activation of AKT2	R-HSA-165158	4.842816e-01	0.315	0	0
RUNX1 regulates transcription of genes involved in interleukin signaling	R-HSA-8939247	4.842816e-01	0.315	0	0
Reelin signalling pathway	R-HSA-8866376	4.842816e-01	0.315	0	0
NTRK2 activates RAC1	R-HSA-9032759	4.842816e-01	0.315	0	0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	R-HSA-3134973	4.842816e-01	0.315	0	0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	R-HSA-3134963	4.842816e-01	0.315	0	0
The phototransduction cascade	R-HSA-2514856	4.849462e-01	0.314	0	0
TNFR2 non-canonical NF-kB pathway	R-HSA-5668541	4.917469e-01	0.308	0	0
Translation of Structural Proteins	R-HSA-9683701	4.933741e-01	0.307	0	0
PI-3K cascade:FGFR1	R-HSA-5654689	4.937429e-01	0.306	0	0
Notch-HLH transcription pathway	R-HSA-350054	4.937429e-01	0.306	0	0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	R-HSA-9670439	4.937429e-01	0.306	0	0
LDL clearance	R-HSA-8964038	4.937429e-01	0.306	0	0
Signaling by KIT in disease	R-HSA-9669938	4.937429e-01	0.306	0	0
Ethanol oxidation	R-HSA-71384	4.937429e-01	0.306	0	0
Plasma lipoprotein assembly, remodeling, and clearance	R-HSA-174824	4.974716e-01	0.303	0	0
Neurexins and neuroligins	R-HSA-6794361	5.009791e-01	0.300	0	0
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	5.076262e-01	0.294	0	0
Removal of the Flap Intermediate	R-HSA-69166	5.076262e-01	0.294	0	0
Signaling by FGFR4 in disease	R-HSA-5655291	5.076262e-01	0.294	0	0
Physiological factors	R-HSA-5578768	5.076262e-01	0.294	0	0
Zinc transporters	R-HSA-435354	5.076262e-01	0.294	0	0
HDL assembly	R-HSA-8963896	5.076262e-01	0.294	0	0
Nucleotide biosynthesis	R-HSA-8956320	5.168332e-01	0.287	0	0
Protein-protein interactions at synapses	R-HSA-6794362	5.174663e-01	0.286	0	0
IGF1R signaling cascade	R-HSA-2428924	5.218379e-01	0.282	0	0
Effects of PIP2 hydrolysis	R-HSA-114508	5.232609e-01	0.281	0	0
Cardiac conduction	R-HSA-5576891	5.256855e-01	0.279	0	0
RAB GEFs exchange GTP for GDP on RABs	R-HSA-8876198	5.301682e-01	0.276	0	0
Plus-strand DNA synthesis	R-HSA-164525	5.308427e-01	0.275	0	0
CDH11 homotypic and heterotypic interactions	R-HSA-9833576	5.308427e-01	0.275	0	0
Nef Mediated CD8 Down-regulation	R-HSA-182218	5.308427e-01	0.275	0	0
Signaling by Overexpressed Wild-Type EGFR in Cancer	R-HSA-5638302	5.308427e-01	0.275	0	0
Inhibition of Signaling by Overexpressed EGFR	R-HSA-5638303	5.308427e-01	0.275	0	0
Aryl hydrocarbon receptor signalling	R-HSA-8937144	5.308427e-01	0.275	0	0
Pentose phosphate pathway disease	R-HSA-6791465	5.308427e-01	0.275	0	0
Loss of Function of SMAD2/3 in Cancer	R-HSA-3304349	5.308427e-01	0.275	0	0
Cam-PDE 1 activation	R-HSA-111957	5.308427e-01	0.275	0	0
Signalling to p38 via RIT and RIN	R-HSA-187706	5.308427e-01	0.275	0	0
Release of apoptotic factors from the mitochondria	R-HSA-111457	5.308427e-01	0.275	0	0
CLEC7A/inflammasome pathway	R-HSA-5660668	5.308427e-01	0.275	0	0
Regulation of CDH19 Expression and Function	R-HSA-9764302	5.308427e-01	0.275	0	0
SLC15A4:TASL-dependent IRF5 activation	R-HSA-9860276	5.308427e-01	0.275	0	0
Circadian clock	R-HSA-9909396	5.357909e-01	0.271	0	0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	5.362355e-01	0.271	0	0
Erythropoietin activates RAS	R-HSA-9027284	5.364084e-01	0.271	0	0
Beta-catenin phosphorylation cascade	R-HSA-196299	5.364084e-01	0.271	0	0
Processive synthesis on the lagging strand	R-HSA-69183	5.364084e-01	0.271	0	0
Telomere C-strand synthesis initiation	R-HSA-174430	5.364084e-01	0.271	0	0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	R-HSA-450513	5.364084e-01	0.271	0	0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	R-HSA-9673767	5.364084e-01	0.271	0	0
Signaling by PDGFRA extracellular domain mutants	R-HSA-9673770	5.364084e-01	0.271	0	0
RSV-host interactions	R-HSA-9833110	5.370799e-01	0.270	0	0
TRAF6 mediated NF-kB activation	R-HSA-933542	5.395881e-01	0.268	0	0
Plasma lipoprotein assembly	R-HSA-8963898	5.395881e-01	0.268	0	0
Developmental Lineage of Mammary Gland Alveolar Cells	R-HSA-9927426	5.425091e-01	0.266	0	0
NPAS4 regulates expression of target genes	R-HSA-9768919	5.425091e-01	0.266	0	0
RNA polymerase II transcribes snRNA genes	R-HSA-6807505	5.427504e-01	0.265	0	0
XBP1(S) activates chaperone genes	R-HSA-381038	5.427504e-01	0.265	0	0
Disorders of transmembrane transporters	R-HSA-5619115	5.473966e-01	0.262	0	0
G alpha (z) signalling events	R-HSA-418597	5.479282e-01	0.261	0	0
Fcgamma receptor (FCGR) dependent phagocytosis	R-HSA-2029480	5.556136e-01	0.255	0	0
PI-3K cascade:FGFR2	R-HSA-5654695	5.615953e-01	0.251	0	0
Polymerase switching on the C-strand of the telomere	R-HSA-174411	5.615953e-01	0.251	0	0
TGFBR3 expression	R-HSA-9839394	5.615953e-01	0.251	0	0
ADORA2B mediated anti-inflammatory cytokines production	R-HSA-9660821	5.620190e-01	0.250	0	0
Platelet Aggregation (Plug Formation)	R-HSA-76009	5.620190e-01	0.250	0	0
Fanconi Anemia Pathway	R-HSA-6783310	5.620190e-01	0.250	0	0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	R-HSA-1362300	5.640095e-01	0.249	0	0
Induction of Cell-Cell Fusion	R-HSA-9733458	5.640095e-01	0.249	0	0
TP53 Regulates Transcription of Caspase Activators and Caspases	R-HSA-6803207	5.640095e-01	0.249	0	0
Attachment and Entry	R-HSA-9678110	5.640095e-01	0.249	0	0
Differentiation of T cells	R-HSA-9945266	5.640095e-01	0.249	0	0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)	R-HSA-9942503	5.640095e-01	0.249	0	0
HDR through Homologous Recombination (HRR)	R-HSA-5685942	5.644859e-01	0.248	1	0
PTK6 promotes HIF1A stabilization	R-HSA-8857538	5.732026e-01	0.242	0	0
Erythropoietin activates STAT5	R-HSA-9027283	5.732026e-01	0.242	0	0
STAT5 Activation	R-HSA-9645135	5.732026e-01	0.242	0	0
Uncoating of the HIV Virion	R-HSA-162585	5.732026e-01	0.242	0	0
MET Receptor Activation	R-HSA-6806942	5.732026e-01	0.242	0	0
VLDL assembly	R-HSA-8866423	5.732026e-01	0.242	0	0
Neurofascin interactions	R-HSA-447043	5.732026e-01	0.242	0	0
IRS-mediated signalling	R-HSA-112399	5.780927e-01	0.238	0	0
Lysosome Vesicle Biogenesis	R-HSA-432720	5.797599e-01	0.237	0	0
RUNX2 regulates bone development	R-HSA-8941326	5.797599e-01	0.237	0	0
GPVI-mediated activation cascade	R-HSA-114604	5.797599e-01	0.237	0	0
Post-translational protein phosphorylation	R-HSA-8957275	5.806310e-01	0.236	0	0
Mitochondrial biogenesis	R-HSA-1592230	5.828100e-01	0.234	0	0
MET activates PTK2 signaling	R-HSA-8874081	5.829512e-01	0.234	0	0
Signaling by FLT3 fusion proteins	R-HSA-9703465	5.829512e-01	0.234	0	0
Integration of energy metabolism	R-HSA-163685	5.851932e-01	0.233	0	0
GRB2 events in ERBB2 signaling	R-HSA-1963640	5.904082e-01	0.229	0	0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex	R-HSA-9931521	5.904082e-01	0.229	0	0
Synthesis of PG	R-HSA-1483148	5.904082e-01	0.229	0	0
Disorders of Developmental Biology	R-HSA-9675151	5.904082e-01	0.229	0	0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	R-HSA-2892247	5.904082e-01	0.229	0	0
Response to metal ions	R-HSA-5660526	5.904082e-01	0.229	0	0
FOXO-mediated transcription	R-HSA-9614085	5.920226e-01	0.228	0	0
Phosphorylation of CD3 and TCR zeta chains	R-HSA-202427	6.036331e-01	0.219	0	0
Disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	6.036331e-01	0.219	0	0
Insulin processing	R-HSA-264876	6.036331e-01	0.219	0	0
Peroxisomal protein import	R-HSA-9033241	6.072112e-01	0.217	0	0
Deadenylation-dependent mRNA decay	R-HSA-429914	6.072112e-01	0.217	0	0
GPER1 signaling	R-HSA-9634597	6.102624e-01	0.214	0	0
IFNG signaling activates MAPKs	R-HSA-9732724	6.117401e-01	0.213	0	0
TRIF-mediated programmed cell death	R-HSA-2562578	6.117401e-01	0.213	0	0
Disinhibition of SNARE formation	R-HSA-114516	6.117401e-01	0.213	0	0
Recycling of eIF2:GDP	R-HSA-72731	6.117401e-01	0.213	0	0
Insulin effects increased synthesis of Xylulose-5-Phosphate	R-HSA-163754	6.117401e-01	0.213	0	0
Nef Mediated CD4 Down-regulation	R-HSA-167590	6.117401e-01	0.213	0	0
Microbial modulation of RIPK1-mediated regulated necrosis	R-HSA-9686347	6.117401e-01	0.213	0	0
Activated NTRK3 signals through PI3K	R-HSA-9603381	6.117401e-01	0.213	0	0
VLDL clearance	R-HSA-8964046	6.117401e-01	0.213	0	0
LDL remodeling	R-HSA-8964041	6.117401e-01	0.213	0	0
Netrin mediated repulsion signals	R-HSA-418886	6.117401e-01	0.213	0	0
Activated NTRK2 signals through CDK5	R-HSA-9032845	6.117401e-01	0.213	0	0
Unfolded Protein Response (UPR)	R-HSA-381119	6.137566e-01	0.212	0	0
IRE1alpha activates chaperones	R-HSA-381070	6.152053e-01	0.211	0	0
Elastic fibre formation	R-HSA-1566948	6.152098e-01	0.211	0	0
Removal of the Flap Intermediate from the C-strand	R-HSA-174437	6.155966e-01	0.211	0	0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	R-HSA-5358606	6.155966e-01	0.211	0	0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	R-HSA-5358565	6.155966e-01	0.211	0	0
Elevation of cytosolic Ca2+ levels	R-HSA-139853	6.155966e-01	0.211	0	0
Choline catabolism	R-HSA-6798163	6.155966e-01	0.211	0	0
Specification of primordial germ cells	R-HSA-9827857	6.155966e-01	0.211	0	0
Transcriptional and post-translational regulation of MITF-M expression and activity	R-HSA-9856649	6.184648e-01	0.209	0	0
Telomere Extension By Telomerase	R-HSA-171319	6.236244e-01	0.205	0	0
RUNX2 regulates osteoblast differentiation	R-HSA-8940973	6.236244e-01	0.205	0	0
Activation of kainate receptors upon glutamate binding	R-HSA-451326	6.236244e-01	0.205	0	0
Late SARS-CoV-2 Infection Events	R-HSA-9772573	6.266991e-01	0.203	0	0
Interconversion of nucleotide di- and triphosphates	R-HSA-499943	6.313744e-01	0.200	0	0
Pentose phosphate pathway	R-HSA-71336	6.322193e-01	0.199	0	0
Cross-presentation of soluble exogenous antigens (endosomes)	R-HSA-1236978	6.322193e-01	0.199	0	0
Expression of BMAL (ARNTL), CLOCK, and NPAS2	R-HSA-9931509	6.322193e-01	0.199	0	0
Regulation of actin dynamics for phagocytic cup formation	R-HSA-2029482	6.322769e-01	0.199	0	0
G beta:gamma signalling through PLC beta	R-HSA-418217	6.395780e-01	0.194	0	0
Mismatch Repair	R-HSA-5358508	6.395780e-01	0.194	0	0
Apoptotic factor-mediated response	R-HSA-111471	6.395780e-01	0.194	0	0
Presynaptic function of Kainate receptors	R-HSA-500657	6.395780e-01	0.194	0	0
PKA activation in glucagon signalling	R-HSA-164378	6.395780e-01	0.194	0	0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	R-HSA-9926550	6.395780e-01	0.194	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9679504	6.395780e-01	0.194	0	0
Downstream signaling of activated FGFR3	R-HSA-5654708	6.429135e-01	0.192	0	0
Regulation of CDH11 Expression and Function	R-HSA-9759475	6.429135e-01	0.192	0	0
Ca2+ pathway	R-HSA-4086398	6.440333e-01	0.191	0	0
Reverse Transcription of HIV RNA	R-HSA-162589	6.467999e-01	0.189	0	0
Minus-strand DNA synthesis	R-HSA-164516	6.467999e-01	0.189	0	0
EGFR interacts with phospholipase C-gamma	R-HSA-212718	6.467999e-01	0.189	0	0
phospho-PLA2 pathway	R-HSA-111995	6.467999e-01	0.189	0	0
Activated NTRK2 signals through PI3K	R-HSA-9028335	6.467999e-01	0.189	0	0
Regulation by c-FLIP	R-HSA-3371378	6.467999e-01	0.189	0	0
Co-stimulation by ICOS	R-HSA-9927354	6.467999e-01	0.189	0	0
FGFR1b ligand binding and activation	R-HSA-190370	6.467999e-01	0.189	0	0
Fructose biosynthesis	R-HSA-5652227	6.467999e-01	0.189	0	0
TGFBR3 PTM regulation	R-HSA-9839383	6.467999e-01	0.189	0	0
Dimerization of procaspase-8	R-HSA-69416	6.467999e-01	0.189	0	0
SLC-mediated bile acid transport	R-HSA-9958517	6.467999e-01	0.189	0	0
Adrenoceptors	R-HSA-390696	6.467999e-01	0.189	0	0
Alpha-defensins	R-HSA-1462054	6.467999e-01	0.189	0	0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	R-HSA-111453	6.467999e-01	0.189	0	0
Activated NTRK2 signals through FYN	R-HSA-9032500	6.467999e-01	0.189	0	0
Heme signaling	R-HSA-9707616	6.487296e-01	0.188	0	0
Signaling by PDGF	R-HSA-186797	6.487296e-01	0.188	0	0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	R-HSA-73779	6.487363e-01	0.188	0	0
Diseases associated with the TLR signaling cascade	R-HSA-5602358	6.487363e-01	0.188	0	0
Diseases of Immune System	R-HSA-5260271	6.487363e-01	0.188	0	0
Interleukin-2 family signaling	R-HSA-451927	6.487363e-01	0.188	0	0
Nuclear signaling by ERBB4	R-HSA-1251985	6.487363e-01	0.188	0	0
Mitochondrial protein degradation	R-HSA-9837999	6.491273e-01	0.188	0	0
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	6.614938e-01	0.179	0	0
Downstream signaling of activated FGFR4	R-HSA-5654716	6.614938e-01	0.179	0	0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	R-HSA-1474151	6.614938e-01	0.179	0	0
Abortive elongation of HIV-1 transcript in the absence of Tat	R-HSA-167242	6.623649e-01	0.179	0	0
E2F mediated regulation of DNA replication	R-HSA-113510	6.623649e-01	0.179	0	0
Erythrocytes take up carbon dioxide and release oxygen	R-HSA-1237044	6.623649e-01	0.179	0	0
Signaling by FGFR2 IIIa TM	R-HSA-8851708	6.623649e-01	0.179	0	0
O2/CO2 exchange in erythrocytes	R-HSA-1480926	6.623649e-01	0.179	0	0
FCERI mediated NF-kB activation	R-HSA-2871837	6.679359e-01	0.175	0	0
TP53 Regulates Transcription of Cell Death Genes	R-HSA-5633008	6.685730e-01	0.175	0	0
Iron uptake and transport	R-HSA-917937	6.685730e-01	0.175	0	0
SLC transporter disorders	R-HSA-5619102	6.734338e-01	0.172	0	0
Insulin receptor signalling cascade	R-HSA-74751	6.748710e-01	0.171	0	0
Neddylation	R-HSA-8951664	6.763167e-01	0.170	0	0
NFE2L2 regulating MDR associated enzymes	R-HSA-9818032	6.786958e-01	0.168	0	0
Estrogen-stimulated signaling through PRKCZ	R-HSA-9634635	6.786958e-01	0.168	0	0
CASP8 activity is inhibited	R-HSA-5218900	6.786958e-01	0.168	0	0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	R-HSA-5649702	6.786958e-01	0.168	0	0
Activation of the AP-1 family of transcription factors	R-HSA-450341	6.786958e-01	0.168	0	0
mRNA Editing	R-HSA-75072	6.786958e-01	0.168	0	0
MAPK1 (ERK2) activation	R-HSA-112411	6.786958e-01	0.168	0	0
Regulation of signaling by NODAL	R-HSA-1433617	6.786958e-01	0.168	0	0
Regulation of CDH11 gene transcription	R-HSA-9762293	6.786958e-01	0.168	0	0
Interleukin-1 processing	R-HSA-448706	6.786958e-01	0.168	0	0
NOTCH4 Activation and Transmission of Signal to the Nucleus	R-HSA-9013700	6.786958e-01	0.168	0	0
Cellular response to mitochondrial stress	R-HSA-9840373	6.786958e-01	0.168	0	0
Caspase activation via Dependence Receptors in the absence of ligand	R-HSA-418889	6.786958e-01	0.168	0	0
RNA Polymerase II HIV Promoter Escape	R-HSA-167162	6.802635e-01	0.167	0	0
HIV Transcription Initiation	R-HSA-167161	6.802635e-01	0.167	0	0
RNA Polymerase II Transcription Initiation	R-HSA-75953	6.802635e-01	0.167	0	0
Innate Immune System	R-HSA-168249	6.804997e-01	0.167	0	0
Regulation of PD-L1(CD274) translation	R-HSA-9909620	6.839776e-01	0.165	0	0
Formation of ATP by chemiosmotic coupling	R-HSA-163210	6.839776e-01	0.165	0	0
VxPx cargo-targeting to cilium	R-HSA-5620916	6.839776e-01	0.165	0	0
BBSome-mediated cargo-targeting to cilium	R-HSA-5620922	6.839776e-01	0.165	0	0
Translation of Structural Proteins	R-HSA-9694635	6.920410e-01	0.160	0	0
Rab regulation of trafficking	R-HSA-9007101	6.932245e-01	0.159	0	0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	R-HSA-381676	6.952648e-01	0.158	0	0
Signaling by WNT in cancer	R-HSA-4791275	6.965217e-01	0.157	0	0
Integrin cell surface interactions	R-HSA-216083	7.033632e-01	0.153	0	0
MyD88 deficiency (TLR2/4)	R-HSA-5602498	7.044422e-01	0.152	0	0
Lagging Strand Synthesis	R-HSA-69186	7.044422e-01	0.152	0	0
ADP signalling through P2Y purinoceptor 12	R-HSA-392170	7.044422e-01	0.152	0	0
Zygotic genome activation (ZGA)	R-HSA-9819196	7.044422e-01	0.152	0	0
Erythropoietin activates Phospholipase C gamma (PLCG)	R-HSA-9027277	7.077130e-01	0.150	0	0
DNA replication initiation	R-HSA-68952	7.077130e-01	0.150	0	0
Activation of Ca-permeable Kainate Receptor	R-HSA-451308	7.077130e-01	0.150	0	0
Defective RIPK1-mediated regulated necrosis	R-HSA-9693928	7.077130e-01	0.150	0	0
Ion influx/efflux at host-pathogen interface	R-HSA-6803544	7.077130e-01	0.150	0	0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	R-HSA-2151209	7.077130e-01	0.150	0	0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	R-HSA-428359	7.077130e-01	0.150	0	0
CASP4 inflammasome assembly	R-HSA-9948001	7.077130e-01	0.150	0	0
MECP2 regulates transcription of neuronal ligands	R-HSA-9022702	7.077130e-01	0.150	0	0
Sperm Motility And Taxes	R-HSA-1300642	7.077130e-01	0.150	0	0
MAPK3 (ERK1) activation	R-HSA-110056	7.077130e-01	0.150	0	0
Metal sequestration by antimicrobial proteins	R-HSA-6799990	7.077130e-01	0.150	0	0
RNA Polymerase II Promoter Escape	R-HSA-73776	7.097556e-01	0.149	0	0
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	7.116165e-01	0.148	0	0
Regulation of Expression and Function of Type II Classical Cadherins	R-HSA-9764260	7.129753e-01	0.147	0	0
Synthesis of IP3 and IP4 in the cytosol	R-HSA-1855204	7.129753e-01	0.147	0	0
Class I MHC mediated antigen processing & presentation	R-HSA-983169	7.228492e-01	0.141	0	0
IRAK4 deficiency (TLR2/4)	R-HSA-5603041	7.237897e-01	0.140	0	0
FRS-mediated FGFR3 signaling	R-HSA-5654706	7.237897e-01	0.140	0	0
Attachment and Entry	R-HSA-9694614	7.237897e-01	0.140	0	0
Metabolism of Angiotensinogen to Angiotensins	R-HSA-2022377	7.237897e-01	0.140	0	0
Ribavirin ADME	R-HSA-9755088	7.237897e-01	0.140	0	0
Glucagon signaling in metabolic regulation	R-HSA-163359	7.287312e-01	0.137	0	0
EGR2 and SOX10-mediated initiation of Schwann cell myelination	R-HSA-9619665	7.287312e-01	0.137	0	0
LGI-ADAM interactions	R-HSA-5682910	7.341112e-01	0.134	0	0
Ionotropic activity of kainate receptors	R-HSA-451306	7.341112e-01	0.134	0	0
vRNP Assembly	R-HSA-192905	7.341112e-01	0.134	0	0
vRNA Synthesis	R-HSA-192814	7.341112e-01	0.134	0	0
Chylomicron assembly	R-HSA-8963888	7.341112e-01	0.134	0	0
Bicarbonate transporters	R-HSA-425381	7.341112e-01	0.134	0	0
SARS-CoV-2 modulates autophagy	R-HSA-9754560	7.341112e-01	0.134	0	0
RUNX2 regulates genes involved in cell migration	R-HSA-8941332	7.341112e-01	0.134	0	0
CD163 mediating an anti-inflammatory response	R-HSA-9662834	7.341112e-01	0.134	0	0
Dissolution of Fibrin Clot	R-HSA-75205	7.341112e-01	0.134	0	0
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	7.356539e-01	0.133	0	0
RNA Polymerase II Transcription Initiation And Promoter Clearance	R-HSA-76042	7.372112e-01	0.132	0	0
Somitogenesis	R-HSA-9824272	7.372112e-01	0.132	0	0
Metabolism of amino acids and derivatives	R-HSA-71291	7.376607e-01	0.132	0	0
FRS-mediated FGFR4 signaling	R-HSA-5654712	7.420551e-01	0.130	0	0
RAF-independent MAPK1/3 activation	R-HSA-112409	7.420551e-01	0.130	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9694676	7.420551e-01	0.130	0	0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	R-HSA-6814122	7.437996e-01	0.129	0	0
Signal amplification	R-HSA-392518	7.437996e-01	0.129	0	0
Early SARS-CoV-2 Infection Events	R-HSA-9772572	7.466215e-01	0.127	0	0
Cell recruitment (pro-inflammatory response)	R-HSA-9664424	7.501827e-01	0.125	0	0
Purinergic signaling in leishmaniasis infection	R-HSA-9660826	7.501827e-01	0.125	0	0
Cytoprotection by HMOX1	R-HSA-9707564	7.557740e-01	0.122	0	0
Post-translational protein modification	R-HSA-597592	7.573737e-01	0.121	0	0
Extension of Telomeres	R-HSA-180786	7.580776e-01	0.120	0	0
Synthesis of diphthamide-EEF2	R-HSA-5358493	7.581266e-01	0.120	0	0
Condensation of Prometaphase Chromosomes	R-HSA-2514853	7.581266e-01	0.120	0	0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters	R-HSA-9931512	7.581266e-01	0.120	0	0
POLB-Dependent Long Patch Base Excision Repair	R-HSA-110362	7.581266e-01	0.120	0	0
ERKs are inactivated	R-HSA-202670	7.581266e-01	0.120	0	0
Viral RNP Complexes in the Host Cell Nucleus	R-HSA-168330	7.581266e-01	0.120	0	0
Downstream signaling of activated FGFR2	R-HSA-5654696	7.581928e-01	0.120	0	0
Downstream signaling of activated FGFR1	R-HSA-5654687	7.581928e-01	0.120	0	0
PERK regulates gene expression	R-HSA-381042	7.581928e-01	0.120	0	0
RNA Pol II CTD phosphorylation and interaction with CE	R-HSA-77075	7.592758e-01	0.120	0	0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	R-HSA-167160	7.592758e-01	0.120	0	0
Regulation of PTEN mRNA translation	R-HSA-8943723	7.592758e-01	0.120	0	0
Interleukin receptor SHC signaling	R-HSA-912526	7.592758e-01	0.120	0	0
Formation of the ureteric bud	R-HSA-9830674	7.592758e-01	0.120	0	0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	R-HSA-381426	7.596487e-01	0.119	0	0
RAB geranylgeranylation	R-HSA-8873719	7.691401e-01	0.114	0	0
Sphingolipid de novo biosynthesis	R-HSA-1660661	7.691401e-01	0.114	0	0
Triglyceride catabolism	R-HSA-163560	7.719250e-01	0.112	0	0
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	7.745884e-01	0.111	0	0
Metal ion SLC transporters	R-HSA-425410	7.746408e-01	0.111	0	0
Translocation of ZAP-70 to Immunological synapse	R-HSA-202430	7.754916e-01	0.110	0	0
ADP signalling through P2Y purinoceptor 1	R-HSA-418592	7.754916e-01	0.110	0	0
Diseases of carbohydrate metabolism	R-HSA-5663084	7.763834e-01	0.110	0	0
Formation of paraxial mesoderm	R-HSA-9793380	7.798132e-01	0.108	0	0
MET activates RAS signaling	R-HSA-8851805	7.799742e-01	0.108	0	0
Scavenging by Class F Receptors	R-HSA-3000484	7.799742e-01	0.108	0	0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex	R-HSA-9931530	7.799742e-01	0.108	0	0
GRB2 events in EGFR signaling	R-HSA-179812	7.799742e-01	0.108	0	0
Serotonin clearance from the synaptic cleft	R-HSA-380615	7.799742e-01	0.108	0	0
Regulation of FOXO transcriptional activity by acetylation	R-HSA-9617629	7.799742e-01	0.108	0	0
Interleukin-15 signaling	R-HSA-8983432	7.799742e-01	0.108	0	0
Trafficking and processing of endosomal TLR	R-HSA-1679131	7.799742e-01	0.108	0	0
Role of second messengers in netrin-1 signaling	R-HSA-418890	7.799742e-01	0.108	0	0
NOTCH2 intracellular domain regulates transcription	R-HSA-2197563	7.799742e-01	0.108	0	0
Interferon gamma signaling	R-HSA-877300	7.829545e-01	0.106	0	0
FRS-mediated FGFR1 signaling	R-HSA-5654693	7.907434e-01	0.102	0	0
Acyl chain remodelling of PS	R-HSA-1482801	7.907434e-01	0.102	0	0
Laminin interactions	R-HSA-3000157	7.907434e-01	0.102	0	0
Glycogen breakdown (glycogenolysis)	R-HSA-70221	7.907434e-01	0.102	0	0
PIWI-interacting RNA (piRNA) biogenesis	R-HSA-5601884	7.907434e-01	0.102	0	0
Formation of the nephric duct	R-HSA-9830364	7.907434e-01	0.102	0	0
Metabolism of carbohydrates and carbohydrate derivatives	R-HSA-71387	7.962095e-01	0.099	0	0
Signaling by FGFR2 in disease	R-HSA-5655253	7.971706e-01	0.098	0	0
Transcriptional regulation of pluripotent stem cells	R-HSA-452723	7.974709e-01	0.098	0	0
SLC-mediated transport of inorganic anions	R-HSA-9958790	7.974709e-01	0.098	0	0
Microbial factors inhibit CASP4 activity	R-HSA-9956593	7.998496e-01	0.097	0	0
Formation of axial mesoderm	R-HSA-9796292	7.998496e-01	0.097	0	0
FGFR1c ligand binding and activation	R-HSA-190373	7.998496e-01	0.097	0	0
PI5P Regulates TP53 Acetylation	R-HSA-6811555	7.998496e-01	0.097	0	0
Platelet Adhesion to exposed collagen	R-HSA-75892	7.998496e-01	0.097	0	0
Maturation of nucleoprotein	R-HSA-9683610	7.998496e-01	0.097	0	0
Replication of the SARS-CoV-1 genome	R-HSA-9682706	7.998496e-01	0.097	0	0
Activation of gene expression by SREBF (SREBP)	R-HSA-2426168	8.000112e-01	0.097	0	0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	R-HSA-9931510	8.050731e-01	0.094	0	0
Adrenaline,noradrenaline inhibits insulin secretion	R-HSA-400042	8.050731e-01	0.094	0	0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	R-HSA-110373	8.050731e-01	0.094	0	0
Caspase activation via extrinsic apoptotic signalling pathway	R-HSA-5357769	8.050731e-01	0.094	0	0
Synthesis of PIPs at the Golgi membrane	R-HSA-1660514	8.050731e-01	0.094	0	0
Regulation of insulin secretion	R-HSA-422356	8.072593e-01	0.093	0	0
Respiratory syncytial virus (RSV) genome replication, transcription and translation	R-HSA-9820965	8.093197e-01	0.092	0	0
Developmental Cell Lineages of the Exocrine Pancreas	R-HSA-9820448	8.134126e-01	0.090	0	0
Transcriptional Regulation by NPAS4	R-HSA-9634815	8.178469e-01	0.087	0	0
Uptake and actions of bacterial toxins	R-HSA-5339562	8.178469e-01	0.087	0	0
CLEC7A (Dectin-1) induces NFAT activation	R-HSA-5607763	8.179307e-01	0.087	0	0
CRMPs in Sema3A signaling	R-HSA-399956	8.179307e-01	0.087	0	0
Hydrolysis of LPC	R-HSA-1483115	8.179307e-01	0.087	0	0
Prolactin receptor signaling	R-HSA-1170546	8.179307e-01	0.087	0	0
Respiratory syncytial virus genome transcription	R-HSA-9828642	8.179307e-01	0.087	0	0
Malate-aspartate shuttle	R-HSA-9856872	8.179307e-01	0.087	0	0
Non-canonical inflammasome activation	R-HSA-9686114	8.179307e-01	0.087	0	0
Acyl chain remodeling of CL	R-HSA-1482798	8.179307e-01	0.087	0	0
SARS-CoV-1 Genome Replication and Transcription	R-HSA-9679514	8.179307e-01	0.087	0	0
Processive synthesis on the C-strand of the telomere	R-HSA-174414	8.185227e-01	0.087	0	0
RNA Polymerase I Transcription Termination	R-HSA-73863	8.185227e-01	0.087	0	0
Signaling by FGFR3 in disease	R-HSA-5655332	8.185227e-01	0.087	0	0
Formation of the HIV-1 Early Elongation Complex	R-HSA-167158	8.311343e-01	0.080	0	0
Formation of the Early Elongation Complex	R-HSA-113418	8.311343e-01	0.080	0	0
FRS-mediated FGFR2 signaling	R-HSA-5654700	8.311343e-01	0.080	0	0
ATF4 activates genes in response to endoplasmic reticulum stress	R-HSA-380994	8.311343e-01	0.080	0	0
Adenylate cyclase inhibitory pathway	R-HSA-170670	8.343793e-01	0.079	0	0
SHC1 events in EGFR signaling	R-HSA-180336	8.343793e-01	0.079	0	0
G beta:gamma signalling through BTK	R-HSA-8964315	8.343793e-01	0.079	0	0
Protein lipoylation	R-HSA-9857492	8.343793e-01	0.079	0	0
Lysosphingolipid and LPA receptors	R-HSA-419408	8.343793e-01	0.079	0	0
Other semaphorin interactions	R-HSA-416700	8.343793e-01	0.079	0	0
Telomere C-strand (Lagging Strand) Synthesis	R-HSA-174417	8.413979e-01	0.075	0	0
Intra-Golgi traffic	R-HSA-6811438	8.413979e-01	0.075	0	0
SLC-mediated transport of neurotransmitters	R-HSA-442660	8.413979e-01	0.075	0	0
mRNA Capping	R-HSA-72086	8.429494e-01	0.074	0	0
Regulation of pyruvate dehydrogenase (PDH) complex	R-HSA-204174	8.429494e-01	0.074	0	0
Regulation of gene expression in beta cells	R-HSA-210745	8.429494e-01	0.074	0	0
Glucagon-type ligand receptors	R-HSA-420092	8.429494e-01	0.074	0	0
Defective GALNT12 causes CRCS1	R-HSA-5083636	8.493429e-01	0.071	0	0
Entry of Influenza Virion into Host Cell via Endocytosis	R-HSA-168275	8.493429e-01	0.071	0	0
Defective GALNT3 causes HFTC	R-HSA-5083625	8.493429e-01	0.071	0	0
Caspase activation via Death Receptors in the presence of ligand	R-HSA-140534	8.493429e-01	0.071	0	0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	R-HSA-399955	8.493429e-01	0.071	0	0
Class I peroxisomal membrane protein import	R-HSA-9603798	8.493429e-01	0.071	0	0
WNT5:FZD7-mediated leishmania damping	R-HSA-9673324	8.493429e-01	0.071	0	0
Killing mechanisms	R-HSA-9664420	8.493429e-01	0.071	0	0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	R-HSA-434316	8.493429e-01	0.071	0	0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	8.493429e-01	0.071	0	0
Activation of SMO	R-HSA-5635838	8.493429e-01	0.071	0	0
Cytosolic tRNA aminoacylation	R-HSA-379716	8.510010e-01	0.070	0	0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	R-HSA-9933387	8.540090e-01	0.069	0	0
TBC/RABGAPs	R-HSA-8854214	8.600930e-01	0.065	0	0
Glycine degradation	R-HSA-6783984	8.629553e-01	0.064	0	0
TRAF3-dependent IRF activation pathway	R-HSA-918233	8.629553e-01	0.064	0	0
STAT5 activation downstream of FLT3 ITD mutants	R-HSA-9702518	8.629553e-01	0.064	0	0
Fibronectin matrix formation	R-HSA-1566977	8.629553e-01	0.064	0	0
Biosynthesis of maresin-like SPMs	R-HSA-9027307	8.629553e-01	0.064	0	0
Heme assimilation	R-HSA-9927020	8.629553e-01	0.064	0	0
Transcriptional regulation of testis differentiation	R-HSA-9690406	8.629553e-01	0.064	0	0
tRNA modification in the mitochondrion	R-HSA-6787450	8.629553e-01	0.064	0	0
Galactose catabolism	R-HSA-70370	8.629553e-01	0.064	0	0
Coenzyme A biosynthesis	R-HSA-196783	8.629553e-01	0.064	0	0
Respiratory syncytial virus (RSV) attachment and entry	R-HSA-9820960	8.643532e-01	0.063	0	0
Amine ligand-binding receptors	R-HSA-375280	8.686945e-01	0.061	0	0
Inwardly rectifying K+ channels	R-HSA-1296065	8.740208e-01	0.058	0	0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells	R-HSA-9937080	8.740208e-01	0.058	0	0
Defective C1GALT1C1 causes TNPS	R-HSA-5083632	8.753385e-01	0.058	0	0
Synthesis of PIPs at the late endosome membrane	R-HSA-1660517	8.753385e-01	0.058	0	0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	R-HSA-164938	8.753385e-01	0.058	0	0
Catecholamine biosynthesis	R-HSA-209905	8.753385e-01	0.058	0	0
Modulation of host responses by IFN-stimulated genes	R-HSA-9909505	8.753385e-01	0.058	0	0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se	R-HSA-2408550	8.753385e-01	0.058	0	0
Uptake and function of anthrax toxins	R-HSA-5210891	8.753385e-01	0.058	0	0
Replication of the SARS-CoV-2 genome	R-HSA-9694686	8.753385e-01	0.058	0	0
Vasopressin regulates renal water homeostasis via Aquaporins	R-HSA-432040	8.768256e-01	0.057	0	0
Cardiogenesis	R-HSA-9733709	8.830497e-01	0.054	0	0
Signaling by Retinoic Acid	R-HSA-5362517	8.838558e-01	0.054	0	0
Metabolism of polyamines	R-HSA-351202	8.838558e-01	0.054	0	0
PCNA-Dependent Long Patch Base Excision Repair	R-HSA-5651801	8.866034e-01	0.052	0	0
FOXO-mediated transcription of cell death genes	R-HSA-9614657	8.866034e-01	0.052	0	0
Cytosolic iron-sulfur cluster assembly	R-HSA-2564830	8.866034e-01	0.052	0	0
Serotonin Neurotransmitter Release Cycle	R-HSA-181429	8.866034e-01	0.052	0	0
RNA Polymerase III Transcription Termination	R-HSA-73980	8.866034e-01	0.052	0	0
FGFR1 ligand binding and activation	R-HSA-190242	8.866034e-01	0.052	0	0
Tie2 Signaling	R-HSA-210993	8.866034e-01	0.052	0	0
Adipogenesis	R-HSA-9843745	8.870304e-01	0.052	0	0
Acyl chain remodelling of PC	R-HSA-1482788	8.914763e-01	0.050	0	0
Vitamin B5 (pantothenate) metabolism	R-HSA-199220	8.914763e-01	0.050	0	0
NCAM signaling for neurite out-growth	R-HSA-375165	8.966858e-01	0.047	0	0
Synthesis of PIPs at the plasma membrane	R-HSA-1660499	8.966858e-01	0.047	0	0
Impaired BRCA2 binding to PALB2	R-HSA-9709603	8.968510e-01	0.047	0	0
Prostacyclin signalling through prostacyclin receptor	R-HSA-392851	8.968510e-01	0.047	0	0
Germ layer formation at gastrulation	R-HSA-9754189	8.968510e-01	0.047	0	0
Pyrimidine biosynthesis	R-HSA-500753	8.968510e-01	0.047	0	0
Pre-NOTCH Processing in Golgi	R-HSA-1912420	8.968510e-01	0.047	0	0
Maturation of nucleoprotein	R-HSA-9694631	8.968510e-01	0.047	0	0
Strand-asynchronous mitochondrial DNA replication	R-HSA-9913635	8.968510e-01	0.047	0	0
SARS-CoV-2 Genome Replication and Transcription	R-HSA-9694682	8.968510e-01	0.047	0	0
Regulation of TLR by endogenous ligand	R-HSA-5686938	8.993356e-01	0.046	0	0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	R-HSA-983170	8.993356e-01	0.046	0	0
RA biosynthesis pathway	R-HSA-5365859	8.993356e-01	0.046	0	0
BMAL1:CLOCK,NPAS2 activates circadian expression	R-HSA-1368108	8.993356e-01	0.046	0	0
Formation of the cornified envelope	R-HSA-6809371	9.035618e-01	0.044	0	0
Defective homologous recombination repair (HRR) due to PALB2 loss of function	R-HSA-9701193	9.061731e-01	0.043	0	0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	R-HSA-9701192	9.061731e-01	0.043	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	R-HSA-9704646	9.061731e-01	0.043	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	R-HSA-9704331	9.061731e-01	0.043	0	0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	R-HSA-9609523	9.061731e-01	0.043	0	0
Signaling by NODAL	R-HSA-1181150	9.061731e-01	0.043	0	0
Acyl chain remodelling of PI	R-HSA-1482922	9.061731e-01	0.043	0	0
Common Pathway of Fibrin Clot Formation	R-HSA-140875	9.061731e-01	0.043	0	0
Pregnenolone biosynthesis	R-HSA-196108	9.061731e-01	0.043	0	0
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-5693616	9.066615e-01	0.043	1	1
Acyl chain remodelling of PE	R-HSA-1482839	9.066615e-01	0.043	0	0
PI Metabolism	R-HSA-1483255	9.083712e-01	0.042	0	0
Regulation of cholesterol biosynthesis by SREBP (SREBF)	R-HSA-1655829	9.132985e-01	0.039	0	0
FGFR2 mutant receptor activation	R-HSA-1839126	9.134860e-01	0.039	0	0
G-protein activation	R-HSA-202040	9.146532e-01	0.039	0	0
Acetylcholine Neurotransmitter Release Cycle	R-HSA-264642	9.146532e-01	0.039	0	0
Phenylalanine metabolism	R-HSA-8964208	9.146532e-01	0.039	0	0
Abacavir metabolism	R-HSA-2161541	9.146532e-01	0.039	0	0
Acyl chain remodelling of PG	R-HSA-1482925	9.146532e-01	0.039	0	0
Extracellular matrix organization	R-HSA-1474244	9.159097e-01	0.038	0	0
Signaling by Insulin receptor	R-HSA-74752	9.189876e-01	0.037	0	0
Molybdenum cofactor biosynthesis	R-HSA-947581	9.223673e-01	0.035	0	0
Signaling by NTRK3 (TRKC)	R-HSA-9034015	9.223673e-01	0.035	0	0
Mitochondrial calcium ion transport	R-HSA-8949215	9.223673e-01	0.035	0	0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	R-HSA-983695	9.231366e-01	0.035	0	0
Homologous DNA Pairing and Strand Exchange	R-HSA-5693579	9.257526e-01	0.034	1	0
Parasite infection	R-HSA-9664407	9.260799e-01	0.033	0	0
FCGR3A-mediated phagocytosis	R-HSA-9664422	9.260799e-01	0.033	0	0
Leishmania phagocytosis	R-HSA-9664417	9.260799e-01	0.033	0	0
Dopamine Neurotransmitter Release Cycle	R-HSA-212676	9.293846e-01	0.032	0	0
Fructose metabolism	R-HSA-5652084	9.293846e-01	0.032	0	0
Termination of O-glycan biosynthesis	R-HSA-977068	9.357680e-01	0.029	0	0
Response of EIF2AK1 (HRI) to heme deficiency	R-HSA-9648895	9.357680e-01	0.029	0	0
Free fatty acids regulate insulin secretion	R-HSA-400451	9.357680e-01	0.029	0	0
Biosynthesis of maresins	R-HSA-9018682	9.357680e-01	0.029	0	0
Synthesis of UDP-N-acetyl-glucosamine	R-HSA-446210	9.357680e-01	0.029	0	0
Organic anion transport by SLCO transporters	R-HSA-879518	9.357680e-01	0.029	0	0
Carnitine shuttle	R-HSA-200425	9.357680e-01	0.029	0	0
Infection with Mycobacterium tuberculosis	R-HSA-9635486	9.398436e-01	0.027	0	0
Maturation of spike protein	R-HSA-9694548	9.411141e-01	0.026	0	0
CYP2E1 reactions	R-HSA-211999	9.415747e-01	0.026	0	0
Thromboxane signalling through TP receptor	R-HSA-428930	9.415747e-01	0.026	0	0
Signaling by FLT3 ITD and TKD mutants	R-HSA-9703648	9.415747e-01	0.026	0	0
Norepinephrine Neurotransmitter Release Cycle	R-HSA-181430	9.415747e-01	0.026	0	0
Complex III assembly	R-HSA-9865881	9.415747e-01	0.026	0	0
Mitochondrial RNA degradation	R-HSA-9836573	9.415747e-01	0.026	0	0
Synthesis of PA	R-HSA-1483166	9.446406e-01	0.025	0	0
G protein gated Potassium channels	R-HSA-1296059	9.468567e-01	0.024	0	0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	R-HSA-997272	9.468567e-01	0.024	0	0
Activation of G protein gated Potassium channels	R-HSA-1296041	9.468567e-01	0.024	0	0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	R-HSA-5693554	9.468567e-01	0.024	0	0
Synthesis of PIPs at the early endosome membrane	R-HSA-1660516	9.468567e-01	0.024	0	0
MicroRNA (miRNA) biogenesis	R-HSA-203927	9.468567e-01	0.024	0	0
Fertilization	R-HSA-1187000	9.468567e-01	0.024	0	0
Activation of GABAB receptors	R-HSA-991365	9.496216e-01	0.022	0	0
GABA B receptor activation	R-HSA-977444	9.496216e-01	0.022	0	0
Glutamate Neurotransmitter Release Cycle	R-HSA-210500	9.516615e-01	0.022	0	0
Regulation of RUNX1 Expression and Activity	R-HSA-8934593	9.516615e-01	0.022	0	0
Sphingolipid catabolism	R-HSA-9845614	9.516615e-01	0.022	0	0
Abacavir ADME	R-HSA-2161522	9.516615e-01	0.022	0	0
Regulation of beta-cell development	R-HSA-186712	9.517973e-01	0.021	0	0
Triglyceride metabolism	R-HSA-8979227	9.517973e-01	0.021	0	0
Assembly of collagen fibrils and other multimeric structures	R-HSA-2022090	9.517973e-01	0.021	0	0
Gastrulation	R-HSA-9758941	9.529442e-01	0.021	0	0
tRNA Aminoacylation	R-HSA-379724	9.550426e-01	0.020	0	0
Aquaporin-mediated transport	R-HSA-445717	9.580825e-01	0.019	0	0
Mitochondrial protein import	R-HSA-1268020	9.609288e-01	0.017	0	0
Protein localization	R-HSA-9609507	9.610021e-01	0.017	0	0
Parasitic Infection Pathways	R-HSA-9824443	9.612777e-01	0.017	0	0
Leishmania infection	R-HSA-9658195	9.612777e-01	0.017	0	0
Diseases of DNA repair	R-HSA-9675135	9.632473e-01	0.016	0	0
Impaired BRCA2 binding to RAD51	R-HSA-9709570	9.636243e-01	0.016	0	0
Thyroxine biosynthesis	R-HSA-209968	9.636243e-01	0.016	0	0
Thrombin signalling through proteinase activated receptors (PARs)	R-HSA-456926	9.669139e-01	0.015	0	0
GABA synthesis, release, reuptake and degradation	R-HSA-888590	9.669139e-01	0.015	0	0
Neurotransmitter clearance	R-HSA-112311	9.669139e-01	0.015	0	0
DAP12 signaling	R-HSA-2424491	9.669139e-01	0.015	0	0
Collagen formation	R-HSA-1474290	9.678842e-01	0.014	0	0
Kidney development	R-HSA-9830369	9.726298e-01	0.012	0	0
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	9.732931e-01	0.012	0	0
HDR through Single Strand Annealing (SSA)	R-HSA-5685938	9.751038e-01	0.011	0	0
Resolution of D-loop Structures through Holliday Junction Intermediates	R-HSA-5693568	9.751038e-01	0.011	0	0
Nuclear RNA decay	R-HSA-9930044	9.751038e-01	0.011	0	0
Resolution of D-Loop Structures	R-HSA-5693537	9.773558e-01	0.010	0	0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	R-HSA-163841	9.788139e-01	0.009	0	0
Amino acids regulate mTORC1	R-HSA-9639288	9.790291e-01	0.009	0	0
Diseases of DNA Double-Strand Break Repair	R-HSA-9675136	9.794042e-01	0.009	0	0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function	R-HSA-9701190	9.794042e-01	0.009	0	0
Glycosaminoglycan-protein linkage region biosynthesis	R-HSA-1971475	9.794042e-01	0.009	0	0
ECM proteoglycans	R-HSA-3000178	9.795115e-01	0.009	0	0
Metabolism of cofactors	R-HSA-8978934	9.795115e-01	0.009	0	0
Transferrin endocytosis and recycling	R-HSA-917977	9.812674e-01	0.008	0	0
Metabolism of ingested SeMet, Sec, MeSec into H2Se	R-HSA-2408508	9.812674e-01	0.008	0	0
Paracetamol ADME	R-HSA-9753281	9.821692e-01	0.008	0	0
RNA Polymerase III Abortive And Retractive Initiation	R-HSA-749476	9.829622e-01	0.007	0	0
Formation of Fibrin Clot (Clotting Cascade)	R-HSA-140877	9.829622e-01	0.007	0	0
RNA Polymerase III Transcription	R-HSA-74158	9.829622e-01	0.007	0	0
Metabolism of amine-derived hormones	R-HSA-209776	9.835630e-01	0.007	0	0
Class B/2 (Secretin family receptors)	R-HSA-373080	9.838368e-01	0.007	0	0
Peptide hormone metabolism	R-HSA-2980736	9.844008e-01	0.007	0	0
Voltage gated Potassium channels	R-HSA-1296072	9.845037e-01	0.007	0	0
TRAF6 mediated IRF7 activation	R-HSA-933541	9.845037e-01	0.007	0	0
Phenylalanine and tyrosine metabolism	R-HSA-8963691	9.845037e-01	0.007	0	0
Lysine catabolism	R-HSA-71064	9.845037e-01	0.007	0	0
tRNA processing in the mitochondrion	R-HSA-6785470	9.859059e-01	0.006	0	0
Asparagine N-linked glycosylation	R-HSA-446203	9.860652e-01	0.006	0	0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	R-HSA-381771	9.871812e-01	0.006	0	0
Nuclear Receptor transcription pathway	R-HSA-383280	9.877708e-01	0.005	0	0
Interleukin-10 signaling	R-HSA-6783783	9.877708e-01	0.005	0	0
GABA receptor activation	R-HSA-977443	9.881520e-01	0.005	0	0
Maturation of TCA enzymes and regulation of TCA cycle	R-HSA-9854311	9.883412e-01	0.005	0	0
rRNA processing in the mitochondrion	R-HSA-8868766	9.883412e-01	0.005	0	0
Mitochondrial tRNA aminoacylation	R-HSA-379726	9.883412e-01	0.005	0	0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	R-HSA-9615017	9.903560e-01	0.004	0	0
Scavenging by Class A Receptors	R-HSA-3000480	9.903560e-01	0.004	0	0
Metabolism of nucleotides	R-HSA-15869	9.907833e-01	0.004	0	0
Incretin synthesis, secretion, and inactivation	R-HSA-400508	9.912289e-01	0.004	0	0
CD22 mediated BCR regulation	R-HSA-5690714	9.914827e-01	0.004	0	0
Defensins	R-HSA-1461973	9.920228e-01	0.003	0	0
Surfactant metabolism	R-HSA-5683826	9.927449e-01	0.003	0	0
Methylation	R-HSA-156581	9.927449e-01	0.003	0	0
Synthesis of Leukotrienes (LT) and Eoxins (EX)	R-HSA-2142691	9.927449e-01	0.003	0	0
DAP12 interactions	R-HSA-2172127	9.927449e-01	0.003	0	0
tRNA modification in the nucleus and cytosol	R-HSA-6782315	9.927852e-01	0.003	0	0
G alpha (s) signalling events	R-HSA-418555	9.930648e-01	0.003	0	0
Role of phospholipids in phagocytosis	R-HSA-2029485	9.935480e-01	0.003	0	0
Collagen biosynthesis and modifying enzymes	R-HSA-1650814	9.938921e-01	0.003	0	0
Synthesis of PC	R-HSA-1483191	9.945423e-01	0.002	0	0
COPII-mediated vesicle transport	R-HSA-204005	9.948320e-01	0.002	0	0
Plasma lipoprotein remodeling	R-HSA-8963899	9.950365e-01	0.002	0	0
Glyoxylate metabolism and glycine degradation	R-HSA-389661	9.954859e-01	0.002	0	0
Chemokine receptors bind chemokines	R-HSA-380108	9.954859e-01	0.002	0	0
Complex IV assembly	R-HSA-9864848	9.962664e-01	0.002	0	0
Branched-chain amino acid catabolism	R-HSA-70895	9.962664e-01	0.002	0	0
Cytosolic sulfonation of small molecules	R-HSA-156584	9.962664e-01	0.002	0	0
ROS and RNS production in phagocytes	R-HSA-1222556	9.963061e-01	0.002	0	0
Citric acid cycle (TCA cycle)	R-HSA-71403	9.966046e-01	0.001	0	0
NR1H2 and NR1H3-mediated signaling	R-HSA-9024446	9.971322e-01	0.001	0	0
FCGR3A-mediated IL10 synthesis	R-HSA-9664323	9.971513e-01	0.001	0	0
SLC-mediated transport of organic anions	R-HSA-9955298	9.973648e-01	0.001	0	0
Anti-inflammatory response favouring Leishmania parasite infection	R-HSA-9662851	9.974973e-01	0.001	0	0
Leishmania parasite growth and survival	R-HSA-9664433	9.974973e-01	0.001	0	0
Potassium Channels	R-HSA-1296071	9.975454e-01	0.001	0	0
G alpha (q) signalling events	R-HSA-416476	9.977421e-01	0.001	0	0
Dectin-2 family	R-HSA-5621480	9.978879e-01	0.001	0	0
Synthesis of bile acids and bile salts	R-HSA-192105	9.980601e-01	0.001	0	0
Visual phototransduction	R-HSA-2187338	9.982400e-01	0.001	0	0
Aerobic respiration and respiratory electron transport	R-HSA-1428517	9.983158e-01	0.001	0	0
Collagen degradation	R-HSA-1442490	9.985554e-01	0.001	0	0
Complex I biogenesis	R-HSA-6799198	9.988054e-01	0.001	0	0
Xenobiotics	R-HSA-211981	9.989137e-01	0.000	0	0
Neurotransmitter release cycle	R-HSA-112310	9.991312e-01	0.000	0	0
Cell surface interactions at the vascular wall	R-HSA-202733	9.991617e-01	0.000	0	0
Metabolism of steroid hormones	R-HSA-196071	9.991831e-01	0.000	0	0
Keratinization	R-HSA-6805567	9.991838e-01	0.000	0	0
Bile acid and bile salt metabolism	R-HSA-194068	9.992522e-01	0.000	0	0
O-linked glycosylation of mucins	R-HSA-913709	9.992571e-01	0.000	0	0
Antimicrobial peptides	R-HSA-6803157	9.993098e-01	0.000	0	0
FCERI mediated MAPK activation	R-HSA-2871796	9.993631e-01	0.000	0	0
Fatty acyl-CoA biosynthesis	R-HSA-75105	9.993857e-01	0.000	0	0
Diseases associated with O-glycosylation of proteins	R-HSA-3906995	9.994414e-01	0.000	0	0
Metal ion assimilation from the host	R-HSA-9638482	9.994414e-01	0.000	0	0
Purine catabolism	R-HSA-74259	9.994921e-01	0.000	0	0
G alpha (i) signalling events	R-HSA-418594	9.994948e-01	0.000	0	0
Aspirin ADME	R-HSA-9749641	9.995381e-01	0.000	0	0
Degradation of the extracellular matrix	R-HSA-1474228	9.995438e-01	0.000	0	0
PPARA activates gene expression	R-HSA-1989781	9.997122e-01	0.000	0	0
Developmental Lineage of Pancreatic Acinar Cells	R-HSA-9925561	9.997389e-01	0.000	0	0
Metabolic disorders of biological oxidation enzymes	R-HSA-5579029	9.997389e-01	0.000	0	0
Regulation of lipid metabolism by PPARalpha	R-HSA-400206	9.997518e-01	0.000	0	0
Biosynthesis of DHA-derived SPMs	R-HSA-9018677	9.997841e-01	0.000	0	0
GPCR downstream signalling	R-HSA-388396	9.998533e-01	0.000	0	0
Drug ADME	R-HSA-9748784	9.998730e-01	0.000	0	0
Sulfur amino acid metabolism	R-HSA-1614635	9.998780e-01	0.000	0	0
Phospholipid metabolism	R-HSA-1483257	9.999352e-01	0.000	0	0
FCGR activation	R-HSA-2029481	9.999430e-01	0.000	0	0
Transport of small molecules	R-HSA-382551	9.999439e-01	0.000	0	0
Respiratory electron transport	R-HSA-611105	9.999526e-01	0.000	0	0
Mitochondrial Fatty Acid Beta-Oxidation	R-HSA-77289	9.999529e-01	0.000	0	0
Scavenging of heme from plasma	R-HSA-2168880	9.999572e-01	0.000	0	0
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	9.999611e-01	0.000	0	0
Sphingolipid metabolism	R-HSA-428157	9.999645e-01	0.000	0	0
Bacterial Infection Pathways	R-HSA-9824439	9.999764e-01	0.000	0	0
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	9.999831e-01	0.000	0	0
Signaling by GPCR	R-HSA-372790	9.999924e-01	0.000	0	0
Glycerophospholipid biosynthesis	R-HSA-1483206	9.999932e-01	0.000	0	0
FCERI mediated Ca+2 mobilization	R-HSA-2871809	9.999952e-01	0.000	0	0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	R-HSA-198933	9.999960e-01	0.000	0	0
Sensory perception of sweet, bitter, and umami (glutamate) taste	R-HSA-9717207	9.999978e-01	0.000	0	0
Arachidonate metabolism	R-HSA-2142753	9.999984e-01	0.000	0	0
Nucleotide catabolism	R-HSA-8956319	9.999989e-01	0.000	0	0
Sensory perception of taste	R-HSA-9717189	9.999991e-01	0.000	0	0
Synthesis of substrates in N-glycan biosythesis	R-HSA-446219	9.999991e-01	0.000	0	0
Peptide ligand-binding receptors	R-HSA-375276	9.999993e-01	0.000	0	0
O-linked glycosylation	R-HSA-5173105	9.999996e-01	0.000	0	0
Metabolism of steroids	R-HSA-8957322	9.999998e-01	0.000	0	0
Biosynthesis of specialized proresolving mediators (SPMs)	R-HSA-9018678	9.999998e-01	0.000	0	0
SLC-mediated transmembrane transport	R-HSA-425407	9.999999e-01	0.000	0	0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	R-HSA-446193	9.999999e-01	0.000	0	0
Cytochrome P450 - arranged by substrate type	R-HSA-211897	1.000000e+00	0.000	0	0
Infection with Enterobacteria	R-HSA-9640148	1.000000e+00	0.000	0	0
Phase I - Functionalization of compounds	R-HSA-211945	1.000000e+00	0.000	0	0
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	1.000000e+00	0.000	0	0
Diseases of glycosylation	R-HSA-3781865	1.000000e+00	0.000	0	0
Glycosaminoglycan metabolism	R-HSA-1630316	1.000000e+00	0.000	0	0
Phase II - Conjugation of compounds	R-HSA-156580	1.000000e+00	0.000	0	0
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	1.000000e+00	0.000	0	0
Metabolism of vitamins and cofactors	R-HSA-196854	1.000000e+00	0.000	0	0
Diseases of metabolism	R-HSA-5668914	1.000000e+00	0.000	0	0
Fatty acid metabolism	R-HSA-8978868	1.000000e+00	0.000	0	0
GPCR ligand binding	R-HSA-500792	1.000000e+00	0.000	0	0
Biological oxidations	R-HSA-211859	1.000000e+00	0.000	0	0
Expression and translocation of olfactory receptors	R-HSA-9752946	1.000000e+00	-0.000	0	0
Olfactory Signaling Pathway	R-HSA-381753	1.000000e+00	-0.000	0	0
Metabolism	R-HSA-1430728	1.000000e+00	-0.000	0	0
Metabolism of lipids	R-HSA-556833	1.000000e+00	-0.000	0	0
Sensory Perception	R-HSA-9709957	1.000000e+00	-0.000	0	0