CDK8
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| O43852 | T65 | Sugiyama | CALU | FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD |
| O60664 | S175 | Sugiyama | PLIN3 M6PRBP1 TIP47 | RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK |
| O60841 | S186 | Sugiyama | EIF5B IF2 KIAA0741 | EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN |
| O95714 | S2928 | Sugiyama | HERC2 | ILLGRIRAEEEDLAAVPFLAsDNEEEEDEKGNSGsLIRKKA |
| P00558 | S399 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__ |
| P00558 | T394 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T26 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA |
| P06733 | T55 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP |
| P07205 | S399 | Sugiyama | PGK2 PGKB | CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__ |
| P07205 | T394 | Sugiyama | PGK2 PGKB | GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL |
| P07900 | S165 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK |
| P07900 | S50 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL |
| P07900 | T317 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08195 | S607 | Sugiyama | SLC3A2 MDU1 | ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP |
| P08238 | S160 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S470 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEs |
| P08238 | T309 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | Y457 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK |
| P10809 | S70 | Sugiyama | HSPD1 HSP60 | AVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLKDKY |
| P10809 | T105 | Sugiyama | HSPD1 HSP60 | DLKDKYKNIGAKLVQDVANNtNEEAGDGtttAtVLARSIAK |
| P11142 | S340 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN |
| P13489 | S178 | Sugiyama | RNH1 PRI RNH | SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP |
| P13639 | S578 | Sugiyama | EEF2 EF2 | LKDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNK |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13639 | Y579 | Sugiyama | EEF2 EF2 | KDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKH |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S205 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD |
| P14625 | S64 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR |
| P22059 | S193 | Sugiyama | OSBP OSBP1 | VTALELAKAKAVKMLAEsDEsGDEEsVsQtDKTELQNTLRT |
| P22234 | S27 | Sugiyama | PAICS ADE2 AIRC PAIS | LNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAGNAARK |
| P22314 | S820 | Sugiyama | UBA1 A1S9T UBE1 | tPKsGVKIHVsDQELQsANAsVDDsRLEELKATLPsPDKLP |
| P30050 | S165 | Sugiyama | RPL12 | GRHPHDIIDDINsGAVECPAs____________________ |
| P35579 | S1714 | Sugiyama | MYH9 | RAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQL |
| P42224 | S727 | SIGNOR|PSP | STAT1 | IsVsEVHPSRLQttDNLLPMsPEEFDEVSRIVGsVEFDSMM |
| P46531 | S2513 | SIGNOR|PSP | NOTCH1 TAN1 | PVDNTPSHQLQVPEHPFLtPsPEsPDQWssssPHSNVSDWS |
| P46531 | S2516 | SIGNOR|PSP | NOTCH1 TAN1 | NTPSHQLQVPEHPFLtPsPEsPDQWssssPHSNVSDWSEGV |
| P46531 | T2511 | SIGNOR|PSP | NOTCH1 TAN1 | SSPVDNTPSHQLQVPEHPFLtPsPEsPDQWssssPHSNVSD |
| P46937 | S128 | SIGNOR | YAP1 YAP65 | AstDAGtAGALtPQHVRAHssPAsLQLGAVsPGtLtPtGVV |
| P46937 | S289 | SIGNOR | YAP1 YAP65 | MNQRIsQsAPVKQPPPLAPQsPQGGVMGGsNsNQQQQMRLQ |
| P46937 | S367 | SIGNOR | YAP1 YAP65 | ALRSQLPtLEQDGGtQNPVssPGMsQELRTMttNssDPFLN |
| P46937 | T119 | SIGNOR | YAP1 YAP65 | PEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQLGAVsP |
| P49336 | S244 | Sugiyama | CDK8 | FAELLTSEPIFHCRQEDIKtsNPyHHDQLDRIFNVMGFPAD |
| P49336 | T243 | Sugiyama | CDK8 | IFAELLTSEPIFHCRQEDIKtsNPyHHDQLDRIFNVMGFPA |
| P49336 | Y247 | Sugiyama | CDK8 | LLTSEPIFHCRQEDIKtsNPyHHDQLDRIFNVMGFPADKDW |
| P51946 | S304 | GPS6|SIGNOR|iPTMNet|EPSD|PSP | CCNH | ELALNVITKKRKGYEDDDYVsKKSKHEEEEWtDDDLVEsL_ |
| P51946 | S5 | GPS6|SIGNOR|iPTMNet|EPSD|PSP | CCNH | ________________MYHNsSQKRHWtFSsEEQLARLRAD |
| P52907 | T224 | Sugiyama | CAPZA1 | VQLVSHKDVQDsLtVsNEAQtAKEFIKIIENAENEyQTAIs |
| P60174 | S198 | Sugiyama | TPI1 TPI | TPQQAQEVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtC |
| P60174 | S204 | Sugiyama | TPI1 TPI | EVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQ |
| P60174 | T205 | Sugiyama | TPI1 TPI | VHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQP |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | S60 | Sugiyama | ACTB | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P61981 | S38 | Sugiyama | YWHAG | ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | S62 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P62942 | S68 | Sugiyama | FKBP1A FKBP1 FKBP12 | KFMLGKQEVIRGWEEGVAQMsVGQRAKLTISPDYAYGATGH |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63167 | S21 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAH |
| P63167 | T26 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | S60 | Sugiyama | ACTG1 ACTG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | S61 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P67809 | T108 | Sugiyama | YBX1 NSEP1 YB1 | QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP |
| P67809 | Y99 | Sugiyama | YBX1 NSEP1 YB1 | DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | S62 | Sugiyama | ACTC1 ACTC | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | S62 | Sugiyama | ACTA1 ACTA | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68431 | S11 | SIGNOR|EPSD | H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J | __________MARtKQtARKstGGKAPRKQLATKAARKsAP |
| P84022 | S208 | SIGNOR|EPSD|PSP | SMAD3 MADH3 | DGETSDHQMNHSMDAGsPNLsPNPMsPAHNNLDLQPVTYCE |
| P84022 | S213 | SIGNOR|EPSD|PSP | SMAD3 MADH3 | DHQMNHSMDAGsPNLsPNPMsPAHNNLDLQPVTYCEPAFWC |
| P84022 | T179 | SIGNOR|EPSD|PSP | SMAD3 MADH3 | SIPENTNFPAGIEPQSNIPEtPPPGYLSEDGETSDHQMNHS |
| P84243 | S11 | SIGNOR | H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B | __________MARtKQTARKstGGKAPRKQLATKAARKsAP |
| Q00613 | S363 | Sugiyama | HSF1 HSTF1 | AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE |
| Q01094 | S375 | SIGNOR|EPSD|PSP | E2F1 RBBP3 | QEPLLSRMGsLRAPVDEDRLsPLVAADSLLEHVREDFSGLL |
| Q13200 | S16 | Sugiyama | PSMD2 TRAP2 | _____MEEGGRDKAPVQPQQsPAAAPGGtDEKPsGKERRDA |
| Q13283 | S232 | Sugiyama | G3BP1 G3BP | EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA |
| Q14568 | S165 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK |
| Q14568 | S50 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL |
| Q15080 | S67 | Sugiyama | NCF4 SH3PXD4 | TKGGSKYLIYRRYRQFHALQsKLEERFGPDSKSSALACTLP |
| Q15185 | S113 | Sugiyama | PTGES3 P23 TEBP | RAKLNWLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGD |
| Q15185 | S118 | Sugiyama | PTGES3 P23 TEBP | WLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGDEDVDL |
| Q15293 | T76 | Sugiyama | RCN1 RCN | FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD |
| Q15797 | S187 | SIGNOR|EPSD|PSP | SMAD1 BSP1 MADH1 MADR1 | PLNATFPDSFQQPNSHPFPHsPNSSYPNsPGSSSStYPHsP |
| Q15797 | S195 | SIGNOR|EPSD|PSP | SMAD1 BSP1 MADH1 MADR1 | SFQQPNSHPFPHsPNSSYPNsPGSSSStYPHsPTSSDPGsP |
| Q15797 | S206 | SIGNOR|EPSD|PSP | SMAD1 BSP1 MADH1 MADR1 | HsPNSSYPNsPGSSSStYPHsPTSSDPGsPFQMPADTPPPA |
| Q15797 | S214 | SIGNOR|EPSD|PSP | SMAD1 BSP1 MADH1 MADR1 | NsPGSSSStYPHsPTSSDPGsPFQMPADTPPPAYLPPEDPM |
| Q16695 | S11 | SIGNOR | H3-4 H3FT HIST3H3 | __________MARtKQTARKsTGGKAPRKQLATKVARKsAP |
| Q6UVJ0 | S283 | Sugiyama | SASS6 SAS6 | DLTERKYKGDSTIRELKAKLsGVEEELQRTKQEVLSLRREN |
| Q96C19 | S74 | Sugiyama | EFHD2 SWS1 | ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI |
| Q96D15 | T72 | Sugiyama | RCN3 UNQ239/PRO272 | FQYDHEAFLGREVAKEFDQLtPEEsQARLGRIVDRMDRAGD |
| Q9BQE3 | S439 | Sugiyama | TUBA1C TUBA6 | SEAREDMAALEKDyEEVGADsADGEDEGEEy__________ |
| Q9BX95 | S112 | Sugiyama | SGPP1 SPP1 | GLAAELGPAsPRRAGALRRNsLtGEEGQLARVSNWPLYCLF |
| Q9UNE7 | S23 | Sugiyama | STUB1 CHIP PP1131 | GKEEKEGGARLGAGGGsPEKsPsAQELKEQGNRLFVGRKYP |
Site Promiscuity
path