CDK5

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included

S Sites Probabilities

T Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Sites with acceptor types representing >8% and count ≥10 are included

Download Data Table

Motif clusters with count ≥ 10 are shown

Download

substrate_uniprot	site	source	substrate_genes	site_seq
A5A3E0	S1068	Sugiyama	POTEF A26C1B	SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
O00115	S70	Sugiyama	DNASE2 DNASE2A DNL2	QYKyLDEssGGWRDGRALINsPEGAVGRSLQPLyRSNTSQL
O00151	S130	Sugiyama	PDLIM1 CLIM1 CLP36	PQEVLHIGsAHNRsAMPFtAsPAsSTTARVItNQyNNPAGL
O00267	T806	Sugiyama	SUPT5H SPT5 SPT5H	MYGsQtPLQDGsRtPHyGsQtPLHDGsRtPAQsGAWDPNNP
O00429	S616	EPSD\|PSP	DNM1L DLP1 DRP1	SKAEELLAEEKsKPIPIMPAsPQKGHAVNLLDVPVPVARKL
O00499	T348	PSP	BIN1 AMPHL	LPKsPsQLRKGPPVPPPPKHtPSKEVKQEQILSLFEDTFVP
O14497	S366	Sugiyama	ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1	AAAASGGAQQRsHHAPMsPGssGGGGQPLARtPQPssPMDQ
O14745	S280	Sugiyama	NHERF1 NHERF SLC9A3R1	tNGEIQKENsREALAEAALEsPRPALVRsAssDtsEELNsQ
O14827	S737	GPS6\|EPSD	RASGRF2 GRF2	KsPRLCRKFSSPPPLAVSRTsSPVRARKLsLtSPLNSKIGA
O14939	S134	SIGNOR\|EPSD\|PSP	PLD2	LLRHKVLMSLLPLARFAVAYsPARDAGNREMPsLPRAGPEG
O14976	S456	Sugiyama	GAK DNAJC26	EDVRLFLDSKHPGHYAVYNLsPRTYRPSRFHNRVSECGWAA
O15067	S1062	Sugiyama	PFAS KIAA0361	SYCLPPTFPKAsVPREPGGPsPRVAILREEGSNGDREMADA
O15169	T481	EPSD\|PSP	AXIN1 AXIN	DAHEENPEsILDEHVQRVLRtPGRQsPGPGHRsPDSGHVAK
O15230	S422	Sugiyama	LAMA5 KIAA0533 KIAA1907	GVNCERCLPGFYRSPNHPLDsPHVCRRCNCESDFTDGtCED
O15446	S285	Sugiyama	POLR1G ASE1 CAST CD3EAP PAF49	EDKTVKQEQINTEPLEDtVLsPtKKRKRQKGTEGMEPEEGV
O15516	T451	SIGNOR\|EPSD\|PSP	CLOCK BHLHE8 KIAA0334	sASsRSsRKssHtAVsDPsstPTKIPTDtstPPRQHLPAHE
O15516	T461	SIGNOR\|EPSD\|PSP	CLOCK BHLHE8 KIAA0334	sHtAVsDPsstPTKIPTDtstPPRQHLPAHEKMVQRRSSFS
O43151	S1445	GPS6	TET3 KIAA0401	VSQNGGPSHLWGQYSGGPSMsPKRTNGVGGSWGVFSSGESP
O43151	S1514	GPS6	TET3 KIAA0401	PGEGQQAASHSGGRLRGKPWsPCKFGNSTSALAGPSLTEKP
O43237	S194	Sugiyama	DYNC1LI2 DNCLI2 LIC2	ERKFVKDFQDyMEPEEGCQGsPQRRGPLtsGsDEENVALPL
O43464	S400	SIGNOR\|EPSD\|PSP	HTRA2 OMI PRSS25	REPSFPDVQHGVLIHKVILGsPAHRAGLRPGDVILAIGEQM
O43602	S28	SIGNOR\|iPTMNet\|PSP	DCX DBCN LISX	FDERDKTSRNMRGSRMNGLPsPTHSAHCSFYRTRTLQALsN
O43602	S287	SIGNOR\|iPTMNet	DCX DBCN LISX	DENECRVMKGNPSATAGPKAsPtPQKtSAKsPGPMRRsKsP
O43602	S297	SIGNOR\|iPTMNet	DCX DBCN LISX	NPSATAGPKAsPtPQKtSAKsPGPMRRsKsPADsGNDQDAN
O43602	S306	SIGNOR\|iPTMNet	DCX DBCN LISX	AsPtPQKtSAKsPGPMRRsKsPADsGNDQDANGTSSSQLSt
O43602	S332	SIGNOR\|iPTMNet	DCX DBCN LISX	NDQDANGTSSSQLStPKsKQsPIstPtsPGSLRKHKDLYLP
O43602	S339	SIGNOR\|iPTMNet	DCX DBCN LISX	TSSSQLStPKsKQsPIstPtsPGSLRKHKDLYLPLsLDDsD
O43602	T289	SIGNOR\|iPTMNet	DCX DBCN LISX	NECRVMKGNPSATAGPKAsPtPQKtSAKsPGPMRRsKsPAD
O43602	T326	SIGNOR\|iPTMNet	DCX DBCN LISX	sPADsGNDQDANGTSSSQLStPKsKQsPIstPtsPGSLRKH
O43602	T336	SIGNOR\|iPTMNet	DCX DBCN LISX	ANGTSSSQLStPKsKQsPIstPtsPGSLRKHKDLYLPLsLD
O43765	S77	Sugiyama	SGTA SGT SGT1	TLPEIFEAAATGKEMPQDLRsPARtPPsEEDsAEAERLKTE
O43815	S373	Sugiyama	STRN	KLQDMLANLRDVDELPsLQPsVGsPsRPsssRLPEHEINRA
O43852	T65	Sugiyama	CALU	FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD
O60260	S131	SIGNOR\|EPSD\|PSP	PRKN PARK2	VLPGDSVGLAVILHTDsRKDsPPAGsPAGRSIyNSFYVYCK
O60291	S524	Sugiyama	MGRN1 KIAA0544 RNF156	SssPQQGTRAAsIENVLQDssPEHCGRGPPADIYLPALGPD
O60292	S158	Sugiyama	SIPA1L3 KIAA0545 SPAL3	FHRLSRRRsKDVEFQDGWPRsPGRAFLPLRHRsssEItLSE
O60331	S453	PSP	PIP5K1C KIAA0589	ERFFKFMSNTVFRKNsSLKSsPSKKGRGGALLAVKPLGPTA
O60331	S650	GPS6\|SIGNOR\|iPTMNet\|EPSD\|PSP	PIP5K1C KIAA0589	EEDAPATDIyFPTDERSWVysPLHYSAQAPPAsDGEsDT__
O75052	S266	Sugiyama	NOS1AP CAPON KIAA0464	EGGsHTGSKVSHPQEPMLtAsPRMLLPSSSSKPPGLGTETP
O75122	S541	PSP	CLASP2 KIAA0627	RPsVsQGCsREAsRESsRDTsPVRSFQPLASRHHSRSTGAL
O75223	S136	Sugiyama	GGCT C7orf24 CRF21	EGKEITCRSYLMTNYESAPPsPQYKKIICMGAKENGLPLEy
O75369	S1505	Sugiyama	FLNB FLN1L FLN3 TABP TAP	PSQEGPYMVSVKYADEEIPRsPFKVKVLPTYDASKVtAsGP
O75369	S1602	Sugiyama	FLNB FLN1L FLN3 TABP TAP	PDKtGRYMIGVTYGGDDIPLsPyRIRAtQTGDASKCLAtGP
O75369	S2274	Sugiyama	FLNB FLN1L FLN3 TABP TAP	AQEPGNYEVSIKFNDEHIPEsPyLVPVIAPSDDARRLTVMS
O75369	T980	Sugiyama	FLNB FLN1L FLN3 TABP TAP	KDQEFTVDTRGAGGQGKLDVtILsPsRKVVPCLVtPVtGRE
O75781	S116	Sugiyama	PALM KIAA0270	EVLERGDSAPATAKENAAAPsPVRAPAPsPAKEERKTEVVM
O75794	S299	Sugiyama	CDC123 C10orf7 D123	AQEQDSPAFRCTNSEVtVQPsPyLsyRLPKDFVDLsTGEDA
O75821	S189	Sugiyama	EIF3G EIF3S4	CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK
O75821	T206	Sugiyama	EIF3G EIF3S4	LGLstGEKEKLPGELEPVQAtQNKtGKYVPPsLRDGAsRRG
O75828	S56	Sugiyama	CBR3 SDR21C2	TARDVARGQAAVQQLQAEGLsPRFHQLDIDDLQsIRALRDF
O75832	T108	Sugiyama	PSMD10	IVKALLGKGAQVNAVNQNGCtPLHYAAsKNRHEIAVMLLEG
O94776	S435	Sugiyama	MTA2 MTA1L1 PID	RGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQtFL
O94776	Y437	Sugiyama	MTA2 MTA1L1 PID	tTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQtFLLQ
O94811	S160	GPS6\|SIGNOR\|EPSD\|PSP	TPPP TPPP1	VHRLIEGKAPIISGVTKAIssPtVSRLTDTTKFTGSHKERF
O94811	S18	GPS6\|SIGNOR\|EPSD\|PSP	TPPP TPPP1	___MADKAKPAKAANRtPPKsPGDPsKDRAAKRLsLEsEGA
O94811	T14	GPS6\|SIGNOR\|EPSD\|PSP	TPPP TPPP1	_______MADKAKPAKAANRtPPKsPGDPsKDRAAKRLsLE
O94913	S1493	Sugiyama	PCF11 KIAA0824	IYHPSCYEDYQNTSSFDCtPsPsKtPVENPLNIMLNIVKNE
O94916	T135	GPS6\|SIGNOR\|EPSD\|PSP	NFAT5 KIAA0827 TONEBP	SNRGVsEKQLTSNTVQQHPstPKRHTVLyIsPPPEDLLDNs
O94979	S799	Sugiyama	SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334	IMQLRDRLCRAQGEPVAGHEsPKIPyEKQQLPKGRPGPVAG
O95218	S153	Sugiyama	ZRANB2 ZIS ZNF265	KYRGKAVGPAsILKEVEDKEsEGEEEDEDEDLsKyKLDEDE
O95297	S210	Sugiyama	MPZL1 PZR UNQ849/PRO1787	LYRRKNSKRDyTGCstsEsLsPVKQAPRKsPsDtEGLVKSL
O95425	S920	Sugiyama	SVIL	LDHNAsAtDYKFSssIENsDsPVRSILKSQAWQPLVEGsEN
O95817	S291	SIGNOR\|PSP	BAG3 BIS	QGAssREGsPARsstPLHsPsPIRVHtVVDRPQQPMTHRET
P00558	S399	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558	T168	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558	T394	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL
P01106	S77	PSP	MYC BHLHE39	PPAPSEDIWKKFELLPtPPLsPsRRsGLCsPSyVAVTPFsL
P02545	S22	Sugiyama	LMNA LMN1	ETPsQRRAtRsGAQAsstPLsPtRItRLQEKEDLQELNDRL
P02545	S392	PSP	LMNA LMN1	EIHAYRKLLEGEEERLRLsPsPtsQRsRGRAssHssQtQGG
P04075	S354	Sugiyama	ALDOA ALDA	ANsLACQGKytPsGQAGAAAsEsLFVsNHAy__________
P04075	S356	Sugiyama	ALDOA ALDA	sLACQGKytPsGQAGAAAsEsLFVsNHAy____________
P04075	S36	Sugiyama	ALDOA ALDA	LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075	S360	Sugiyama	ALDOA ALDA	QGKytPsGQAGAAAsEsLFVsNHAy________________
P04075	S39	Sugiyama	ALDOA ALDA	IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075	T37	Sugiyama	ALDOA ALDA	sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04075	Y364	Sugiyama	ALDOA ALDA	tPsGQAGAAAsEsLFVsNHAy____________________
P04083	S201	Sugiyama	ANXA1 ANX1 LPC1	LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04150	S203	SIGNOR\|EPSD\|PSP	NR3C1 GRL	LYTTDQSTFDILQDLEFssGsPGKETNEsPWRSDLLIDENC
P04150	S211	SIGNOR\|EPSD\|PSP	NR3C1 GRL	FDILQDLEFssGsPGKETNEsPWRSDLLIDENCLLsPLAGE
P04150	S226	EPSD\|PSP	NR3C1 GRL	KETNEsPWRSDLLIDENCLLsPLAGEDDSFLLEGNSNEDCK
P04156	S43	EPSD\|PSP	PRNP ALTPRP PRIP PRP	KKRPKPGGWNTGGSRYPGQGsPGGNRYPPQGGGGWGQPHGG
P04406	S210	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG
P04406	S241	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406	T211	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406	T237	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406	Y320	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____
P04637	S15	GPS6\|SIGNOR\|EPSD\|PSP	TP53 P53	______MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPL
P04637	S20	SIGNOR\|EPSD\|PSP	TP53 P53	_MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQAM
P04637	S315	SIGNOR\|iPTMNet	TP53 P53	PHHELPPGStKRALPNNTsssPQPKKKPLDGEyFTLQIRGR
P04637	S33	GPS6\|SIGNOR\|iPTMNet\|EPSD\|PSP	TP53 P53	PLsQEtFsDLWKLLPENNVLsPLPsQAMDDLMLsPDDIEQW
P04637	S46	GPS6\|SIGNOR\|EPSD\|PSP	TP53 P53	LPENNVLsPLPsQAMDDLMLsPDDIEQWFtEDPGPDEAPRM
P04792	S82	Sugiyama	HSPB1 HSP27 HSP28	AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05023	S722	Sugiyama	ATP1A1	VEGCQRQGAIVAVTGDGVNDsPALKKADIGVAMGIAGSDVS
P05067	T743	GPS6\|SIGNOR\|EPSD	APP A4 AD1	LKKKQYtsIHHGVVEVDAAVtPEERHLSKMQQNGyENPtyK
P05187	S177	Sugiyama	ALPP PLAP	RAKKAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADVP
P05386	S101	Sugiyama	RPLP1 RRP1	APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386	S104	Sugiyama	RPLP1 RRP1	tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387	S102	Sugiyama	RPLP2 D11S2243E RPP2	PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387	S105	Sugiyama	RPLP2 D11S2243E RPP2	GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05455	S92	Sugiyama	SSB	LSKSKAELMEIsEDKTKIRRsPsKPLPEVTDEyKNDVKNRs
P06400	S795	EPSD\|PSP	RB1	RPPtLsPIPHIPRsPyKFPssPLRIPGGNIyIsPLKsPYKI
P06400	S807	EPSD\|PSP	RB1	RsPyKFPssPLRIPGGNIyIsPLKsPYKIsEGLPtPtKMtP
P06400	S811	SIGNOR\|EPSD\|PSP	RB1	KFPssPLRIPGGNIyIsPLKsPYKIsEGLPtPtKMtPRSRI
P06733	S27	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL
P06733	S310	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	VsIEDPFDQDDWGAWQKFtAsAGIQVVGDDLTVtNPKRIAK
P06733	S40	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK
P06733	T323	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	AWQKFtAsAGIQVVGDDLTVtNPKRIAKAVNEKsCNCLLLK
P06733	Y44	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06744	S455	Sugiyama	GPI	ALMRGKSTEEARKELQAAGKsPEDLERLLPHKVFEGNRPTN
P07195	S303	Sugiyama	LDHB	GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195	S44	Sugiyama	LDHB	ITVVGVGQVGMACAISILGKsLADELALVDVLEDKLKGEMM
P07195	T323	Sugiyama	LDHB	sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07196	T21	EPSD\|PSP	NEFL NF68 NFL	MSSFSYEPYYSTSYKRRYVEtPRVHISSVRSGYSTARSAYS
P07205	S399	Sugiyama	PGK2 PGKB	CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205	T168	Sugiyama	PGK2 PGKB	EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205	T394	Sugiyama	PGK2 PGKB	GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL
P07437	S115	Sugiyama	TUBB TUBB5 OK/SW-cl.56	sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437	S75	Sugiyama	TUBB TUBB5 OK/SW-cl.56	tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07814	S739	Sugiyama	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV
P07814	S886	GPS6\|SIGNOR\|EPSD\|PSP\|Sugiyama	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	EKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPEAKVLFD
P07814	S999	PSP	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	QKQNDGQRKDPsKNQGGGLsssGAGEGQGPKKQTRLGLEAK
P07814	T737	Sugiyama	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	EKTKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRV
P07858	S216	Sugiyama	CTSB CPSB	PPCTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSE
P07900	S595	PSP	HSP90AA1 HSP90A HSPC1 HSPCA	MKDILEKKVEKVVVSNRLVtsPCCIVtstyGWTANMERIMK
P08195	S296	Sugiyama	SLC3A2 MDU1	DLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNYRGEN
P08195	S402	Sugiyama	SLC3A2 MDU1	SSDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQY
P08195	S598	Sugiyama	SLC3A2 MDU1	LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08195	S607	Sugiyama	SLC3A2 MDU1	ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP
P08238	S462	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238	S468	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238	S497	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238	Y457	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08651	S323	Sugiyama	NFIC NFI	PssPtsSSRNWTEDMEGGIssPVKKtEMDKsPFNsPsPQDs
P08670	S56	GPS6\|EPSD\|PSP	VIM	RtYsLGsALRPstsRsLyAssPGGVyAtRssAVRLRssVPG
P08708	S89	Sugiyama	RPS17 RPS17L	ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL
P08865	T97	Sugiyama	RPSA LAMBR LAMR1	IssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQAAFR
P08908	T314	SIGNOR\|PSP	HTR1A ADRB2RL1 ADRBRL1	EVHRVGNSKEHLPLPSEAGPtPCAPASFERKNERNAEAKRK
P09234	S17	Sugiyama	SNRPC	____MPKFyCDyCDtyLtHDsPsVRKTHCSGRKHKENVKDY
P09234	T11	Sugiyama	SNRPC	__________MPKFyCDyCDtyLtHDsPsVRKTHCSGRKHK
P09874	S782	SIGNOR\|PSP	PARP1 ADPRT PPOL	VEMLDNLLDIEVAySLLRGGsDDssKDPIDVNyEKLKTDIK
P09874	S785	SIGNOR\|PSP	PARP1 ADPRT PPOL	LDNLLDIEVAySLLRGGsDDssKDPIDVNyEKLKTDIKVVD
P09874	S786	SIGNOR\|PSP	PARP1 ADPRT PPOL	DNLLDIEVAySLLRGGsDDssKDPIDVNyEKLKTDIKVVDR
P09923	S174	Sugiyama	ALPI	RAKQAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMP
P0CG38	S1068	Sugiyama	POTEI	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39	S1031	Sugiyama	POTEJ	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DPH7	T56	Sugiyama	TUBA3C TUBA2	MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
P10275	S310	EPSD\|PSP	AR DHTR NR3C4	CKGsLLDDSAGKstEDTAEYsPFKGGYTKGLEGESLGCSGS
P10275	S83	SIGNOR\|EPSD\|PSP	AR DHTR NR3C4	QQQQQQQQQQQQQQQQQQETsPRQQQQQQGEDGsPQAHRRG
P10412	T18	Sugiyama	H1-4 H1F4 HIST1H1E	___MsEtAPAAPAAPAPAEKtPVKKKARKsAGAAKRKAsGP
P10636	S214	GPS6	MAPT MAPTL MTBT1 TAU	GDLHQEGPPLKGAGGKERPGsKEEVDEDRDVDESsPQDsPP
P10636	S235	GPS6\|SIGNOR	MAPT MAPTL MTBT1 TAU	KEEVDEDRDVDESsPQDsPPsKAsPAQDGRPPQTAAREATS
P10636	S396	GPS6	MAPT MAPTL MTBT1 TAU	ARMVSKSKDGtGSDDKKAKTsTRSsAKtLKNRPCLsPKHPT
P10636	S516	SIGNOR	MAPT MAPTL MTBT1 TAU	PKtPPsSGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPtPP
P10636	S519	SIGNOR	MAPT MAPTL MTBT1 TAU	PPsSGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPtPPTRE
P10636	S531	SIGNOR	MAPT MAPTL MTBT1 TAU	RsGyssPGsPGtPGsRsRtPsLPtPPTREPKKVAVVRtPPK
P10636	S552	SIGNOR	MAPT MAPTL MTBT1 TAU	LPtPPTREPKKVAVVRtPPKsPssAKSRLQTAPVPMPDLKN
P10636	S713	SIGNOR	MAPT MAPTL MTBT1 TAU	LTFRENAKAKTDHGAEIVyKsPVVsGDtsPRHLsNVsstGs
P10636	S721	SIGNOR	MAPT MAPTL MTBT1 TAU	AKTDHGAEIVyKsPVVsGDtsPRHLsNVsstGsIDMVDsPQ
P10636	T173	iPTMNet	MAPT MAPTL MTBT1 TAU	MPGAPLLPEGPREATRQPsGtGPEDTEGGRHAPELLKHQLL
P10636	T498	SIGNOR	MAPT MAPTL MTBT1 TAU	GQKGQANATRIPAKtPPAPKtPPsSGEPPKsGDRsGyssPG
P10636	T522	SIGNOR	MAPT MAPTL MTBT1 TAU	SGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPtPPTREPKK
P10636	T529	SIGNOR	MAPT MAPTL MTBT1 TAU	GDRsGyssPGsPGtPGsRsRtPsLPtPPTREPKKVAVVRtP
P10636	T534	SIGNOR	MAPT MAPTL MTBT1 TAU	yssPGsPGtPGsRsRtPsLPtPPTREPKKVAVVRtPPKsPs
P10636	T548	SIGNOR	MAPT MAPTL MTBT1 TAU	RtPsLPtPPTREPKKVAVVRtPPKsPssAKSRLQTAPVPMP
P10809	S225	Sugiyama	HSPD1 HSP60	KtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVL
P10809	S70	Sugiyama	HSPD1 HSP60	AVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLKDKY
P11142	S329	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	LFRGtLDPVEKALRDAKLDKsQIHDIVLVGGstRIPKIQKL
P11142	S340	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142	S40	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142	T37	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P11142	T38	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P11142	T45	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11142	T47	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV
P11142	T66	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11274	T385	Sugiyama	BCR BCR1 D22S11	DKsRsPsQNsQQsFDSssPPtPQCHKRHRHCPVVVSEATIV
P12268	S122	Sugiyama	IMPDH2 IMPD2	NEVRKVKKyEQGFITDPVVLsPKDRVRDVFEAKARHGFCGI
P12270	S2155	Sugiyama	TPR	PstPtLVVPHRtDGFAEAIHsPQVAGVPRFRFGPPEDMPQT
P12277	S164	Sugiyama	CKB CKBB	PHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAEQ
P12277	T35	Sugiyama	CKB CKBB	PAEDEFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDD
P12277	Y39	Sugiyama	CKB CKBB	EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT
P12931	S75	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	SRC SRC1	APAAAEPKLFGGFNssDtVtsPQRAGPLAGGVTTFVALyDY
P13489	S178	Sugiyama	RNH1 PRI RNH	SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13637	S712	Sugiyama	ATP1A3	VEGCQRQGAIVAVTGDGVNDsPALKKADIGVAMGIAGSDVS
P13639	S593	Sugiyama	EEF2 EF2	SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13639	S595	Sugiyama	EEF2 EF2	PVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGLAE
P13639	Y579	Sugiyama	EEF2 EF2	KDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKH
P13798	S185	Sugiyama	APEH D3F15S2 D3S48E DNF15S2	VAEKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQ
P14416	S321	SIGNOR\|EPSD\|PSP	DRD2	SHHQLTLPDPSHHGLHSTPDsPAKPEKNGHAKDHPKIAKIF
P14618	S202	Sugiyama	PKM OIP3 PK2 PK3 PKM2	SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618	S205	Sugiyama	PKM OIP3 PK2 PK3 PKM2	VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618	S37	PSP\|Sugiyama	PKM OIP3 PK2 PK3 PKM2	QLHAAMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRs
P14618	S77	Sugiyama	PKM OIP3 PK2 PK3 PKM2	sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs
P14618	T87	Sugiyama	PKM OIP3 PK2 PK3 PKM2	sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P14625	S515	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	GVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQ
P14625	S552	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	KEKQDKIyFMAGsSRKEAEssPFVERLLKKGyEVIyLTEPV
P14625	S64	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14866	S101	Sugiyama	HNRNPL HNRPL P/OKcl.14	GAAGGGGGGENyDDPHKtPAsPVVHIRGLIDGVVEADLVEA
P14868	S249	Sugiyama	DARS1 DARS PIG40	EGGANVFTVSYFKNNAyLAQsPQLyKQMCICADFEKVFSIG
P15311	T235	SIGNOR\|iPTMNet	EZR VIL2	DLWLGVDALGLNIYEKDDKLtPKIGFPWSEIRNIsFNDKKF
P15336	T71	Sugiyama	ATF2 CREB2 CREBP1	MtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELAsP
P15927	S23	EPSD\|PSP	RPA2 REPA2 RPA32 RPA34	NsGFEsYGsssYGGAGGYtQsPGGFGsPAPsQAEKKSRARA
P15927	S29	EPSD\|PSP	RPA2 REPA2 RPA32 RPA34	YGsssYGGAGGYtQsPGGFGsPAPsQAEKKSRARAQHIVPC
P15927	S33	EPSD\|PSP	RPA2 REPA2 RPA32 RPA34	sYGGAGGYtQsPGGFGsPAPsQAEKKSRARAQHIVPCTIsQ
P16152	S56	Sugiyama	CBR1 CBR CRN SDR21C1	TARDVTRGQAAVQQLQAEGLsPRFHQLDIDDLQsIRALRDF
P16278	S434	Sugiyama	GLB1 ELNR1	GFVLYRTTLPQDCSNPAPLssPLNGVHDRAyVAVDGIPQGV
P16949	S38	SIGNOR\|Sugiyama	STMN1 C1orf215 LAP18 OP18	QAFELILsPRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAE
P17544	T53	Sugiyama	ATF7 ATFA	MTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELASS
P17600	S551	SIGNOR\|iPTMNet	SYN1	RQSRPVAGGPGAPPAARPPAsPsPQRQAGPPQATRQTsVSG
P17600	S553	SIGNOR\|iPTMNet	SYN1	SRPVAGGPGAPPAARPPAsPsPQRQAGPPQATRQTsVSGPA
P17600	S62	iPTMNet	SYN1	ATPGPGTATAERSSGVAPAAsPAAPsPGssGGGGFFSSLSN
P17600	S67	iPTMNet	SYN1	GTATAERSSGVAPAAsPAAPsPGssGGGGFFSSLSNAVKQT
P17706	S304	iPTMNet\|Sugiyama	PTPN2 PTPT	SIQKRWKELsKEDLsPAFDHsPNKIMtEKYNGNRIGLEEEK
P18124	T17	Sugiyama	RPL7	____MEGVEEKKKEVPAVPEtLKKKRRNFAELKIKRLRKKF
P18621	T79	Sugiyama	RPL17	PFRRYNGGVGRCAQAKQWGWtQGRWPKKSAEFLLHMLKNAE
P18669	S31	Sugiyama	PGAM1 PGAMA CDABP0006	HGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALRDAGyE
P18858	S51	Sugiyama	LIG1	TEPPPKAALKEWNGVVsEsDsPVKRPGRKAARVLGsEGEEE
P18887	T453	Sugiyama	XRCC1	PQTKtKPtQAAGPssPQKPPtPEEtKAAsPVLQEDIDIEGV
P20700	T575	Sugiyama	LMNB1 LMN2 LMNB	EEEEEAAGVVVEEELFHQQGtPRASNRSCAIM_________
P20810	S295	Sugiyama	CAST	QEKKRKVEKDtMsDQALEALsAsLGTRQAEPELDLRsIKEV
P20810	S297	Sugiyama	CAST	KKRKVEKDtMsDQALEALsAsLGTRQAEPELDLRsIKEVDE
P21333	S1084	Sugiyama	FLNA FLN FLN1	PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV
P21333	S1459	Sugiyama	FLNA FLN FLN1	KVPVHDVTDASKVKCsGPGLsPGMVRANLPQsFQVDTSKAG
P21333	S1533	Sugiyama	FLNA FLN FLN1	PSREGPysIsVLyGDEEVPRsPFKVKVLPTHDASKVKAsGP
P21333	S1630	Sugiyama	FLNA FLN FLN1	PDVTGRYTILIKYGGDEIPFsPyRVRAVPTGDASKCTVTVS
P21333	S2510	Sugiyama	FLNA FLN FLN1	MAPGsYLISIKYGGPYHIGGsPFKAKVTGPRLVsNHsLHEt
P21860	S1123	SIGNOR\|iPTMNet	ERBB3 HER3	GsEAELQEKVSMCRSRSRSRsPRPRGDSAYHSQRHSLLTPV
P21860	T873	SIGNOR\|iPTMNet	ERBB3 HER3	FGVADLLPPDDKQLLYSEAKtPIKWMALESIHFGKYTHQSD
P22102	S106	Sugiyama	GART PGFT PRGS	LRsAGVQCFGPTAEAAQLEssKRFAKEFMDRHGIPTAQWKA
P22234	S27	Sugiyama	PAICS ADE2 AIRC PAIS	LNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAGNAARK
P22626	S225	Sugiyama	HNRNPA2B1 HNRPA2B1	GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P22626	S259	Sugiyama	HNRNPA2B1 HNRPA2B1	GFGDGyNGyGGGPGGGNFGGsPGyGGGRGGYGGGGPGYGNQ
P22681	S900	Sugiyama	CBL CBL2 RNF55	IAQNNIEMAKNILREFVSIssPAHVAT______________
P23396	S224	Sugiyama	RPS3 OK/SW-cl.26	LPDHVsIVEPKDEILPttPIsEQKGGKPEPPAMPQPVPtA_
P23396	T220	Sugiyama	RPS3 OK/SW-cl.26	PKKPLPDHVsIVEPKDEILPttPIsEQKGGKPEPPAMPQPV
P23396	T221	Sugiyama	RPS3 OK/SW-cl.26	KKPLPDHVsIVEPKDEILPttPIsEQKGGKPEPPAMPQPVP
P23526	T185	Sugiyama	AHCY SAHH	yKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGIKR
P23921	S559	Sugiyama	RRM1 RR1	ALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTPTDLW
P23921	S562	Sugiyama	RRM1 RR1	ASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTPTDLWDWK
P24928	S1875	Sugiyama	POLR2A POLR2	PtsPKysPtsPKysPtsPKysPtsPtysPttPKysPtsPty
P24928	Y1909	Sugiyama	POLR2A POLR2	sPtsPtysPtsPVytPtsPKysPtsPtysPtsPKysPtsPt
P25054	S1100	Sugiyama	APC DP2.5	ESTDDKHLKFQPHFGQQECVsPYRSRGANGSETNRVGSNHG
P25054	S2533	Sugiyama	APC DP2.5	PTIEYNDGRPAKRHDIARsHsEsPSRLPINRSGTWKREHSK
P25205	T722	Sugiyama	MCM3	GDsyDPyDFsDtEEEMPQVHtPKTADsQEtKEsQKVELsES
P25398	Y127	Sugiyama	RPS12	sCVVVKDYGKESQAKDVIEEyFKCKK_______________
P25786	S14	Sugiyama	PSMA1 HC2 NU PROS30 PSC2	_______MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQGSA
P26358	S154	SIGNOR\|EPSD\|PSP	DNMT1 AIM CXXC9 DNMT	KPRTPRRsKsDGEAKPEPsPsPRITRKSTRQttITSHFAKG
P27348	S45	Sugiyama	YWHAQ	CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27695	T233	SIGNOR\|PSP	APEX1 APE APE1 APEX APX HAP1 REF1	VAHEEIDLRNPKGNKKNAGFtPQERQGFGELLQAVPLADSF
P27797	T34	Sugiyama	CALR CRTC	LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P27816	S280	Sugiyama	MAP4	LAKDMALATKTEVALAKDMEsPtKLDVtLAKDMQPSMESDM
P27816	T571	Sugiyama	MAP4	ALKTEAPLAKDGVLtLANNVtPAKDVPPLsEtEAtPVPIKD
P27824	S583	Sugiyama	CANX	VsQEEEDRKPKAEEDEILNRsPRNRKPRRE___________
P28072	T69	Sugiyama	PSMB6 LMPY Y	GADSRTTtGsyIANRVTDKLtPIHDRIFCCRSGSAADTQAV
P29474	S114	GPS6\|SIGNOR\|EPSD\|PSP	NOS3	CTPRRCLGSLVFPRKLQGRPsPGPPAPEQLLSQARDFINQY
P29692	S133	Sugiyama	EEF1D EF1D	NVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPAEDDE
P29692	S60	Sugiyama	EEF1D EF1D	ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL
P29692	S64	Sugiyama	EEF1D EF1D	sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI
P29692	T129	Sugiyama	EEF1D EF1D	EARLNVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPA
P29966	S27	Sugiyama	MARCKS MACS PRKCSL	KTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAsP
P30041	T44	Sugiyama	PRDX6 AOP2 KIAA0106	RFHDFLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKR
P30041	T49	Sugiyama	PRDX6 AOP2 KIAA0106	LGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKLI
P30050	S165	Sugiyama	RPL12	GRHPHDIIDDINsGAVECPAs____________________
P30086	T42	SIGNOR\|PSP\|Sugiyama	PEBP1 PBP PEBP	QHPLHVTYAGAAVDELGKVLtPtQVKNRPtsIsWDGLDsGK
P30101	S443	Sugiyama	PDIA3 ERP57 ERP60 GRP58	LsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLN
P30101	S456	Sugiyama	PDIA3 ERP57 ERP60 GRP58	AtANDVPsPyEVRGFPtIyFsPANKKLNPKKyEGGRELsDF
P30101	Y445	Sugiyama	PDIA3 ERP57 ERP60 GRP58	KDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLNPK
P31146	T424	SIGNOR	CORO1A CORO1	LRVNRGLDtGRRRAAPEAsGtPssDAVSRLEEEMRKLQATV
P31943	S104	Sugiyama	HNRNPH1 HNRPH HNRPH1	EVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK
P31943	T100	Sugiyama	HNRNPH1 HNRPH HNRPH1	HRyVEVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPF
P31946	S47	Sugiyama	YWHAB	AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947	S45	Sugiyama	SFN HME1	FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948	S460	Sugiyama	STIP1	AMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRHD
P33316	S99	Sugiyama	DUT	KGELPKAGGsPAPGPEtPAIsPsKRARPAEVGGMQLRFARL
P33316	T95	Sugiyama	DUT	AAGWKGELPKAGGsPAPGPEtPAIsPsKRARPAEVGGMQLR
P34931	S42	Sugiyama	HSPA1L	VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931	T39	Sugiyama	HSPA1L	CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P34931	T40	Sugiyama	HSPA1L	VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P34931	T47	Sugiyama	HSPA1L	KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34931	T49	Sugiyama	HSPA1L	EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV
P34932	T365	Sugiyama	HSPA4 APG2 HSPH2	TRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAILsP
P35222	S191	GPS6\|EPSD\|PSP	CTNNB1 CTNNB OK/SW-cl.35 PRO2286	AAVMVHQLsKKEAsRHAIMRsPQMVSAIVRTMQNTNDVETA
P35222	S246	GPS6\|EPSD\|PSP	CTNNB1 CTNNB OK/SW-cl.35 PRO2286	EGLLAIFKSGGIPALVKMLGsPVDSVLFYAITTLHNLLLHQ
P35579	S1308	Sugiyama	MYH9	LLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLs
P35579	T1313	Sugiyama	MYH9	DSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLstKLKQ
P35579	T1745	Sugiyama	MYH9	RRLEARIAQLEEELEEEQGNtELINDRLKKANLQIDQINtD
P35611	T724	SIGNOR\|PSP	ADD1 ADDA	DPGsDGSPGKSPsKKKKKFRtPsFLKKSKKKSDS_______
P35612	S604	EPSD\|PSP	ADD2 ADDB	ETAPEEPGsPAKsAPAsPVQsPAKEAEtKsPLVsPsKSLEE
P35612	S617	EPSD\|PSP	ADD2 ADDB	APAsPVQsPAKEAEtKsPLVsPsKSLEEGTKKTETSKAATT
P35612	S701	EPSD\|PSP	ADD2 ADDB	KDKTESVTSGPMsPEGsPsKsPsKKKKKFRTPsFLKKSKKK
P35968	S229	EPSD\|PSP	KDR FLK1 VEGFR2	YQSIMYIVVVVGYRIYDVVLsPSHGIELSVGEKLVLNCTAR
P35998	T193	Sugiyama	PSMC2 MSS1	TYSDVGGCKEQIEKLREVVEtPLLHPERFVNLGIEPPKGVL
P36578	S295	Sugiyama	RPL4 RPL1	sNyNLPMHKMINtDLsRILKsPEIQRALRAPRKKIHRRVLK
P36578	T62	Sugiyama	RPL4 RPL1	TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578	T69	Sugiyama	RPL4 RPL1	RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P37231	S273	EPSD\|PSP	PPARG NR1C3	SFPLTKAKARAILTGKTTDKsPFVIYDMNSLMMGEDKIKFK
P37802	T180	Sugiyama	TAGLN2 KIAA0120 CDABP0035	RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P38646	T87	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	VAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKR
P40763	S727	SIGNOR\|EPSD\|PSP	STAT3 APRF	KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS
P41236	T73	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	PPP1R2 IPP2	LAtyHPADKDyGLMKIDEPstPYHsMMGDDEDACsDtEAtE
P41252	S1047	Sugiyama	IARS1 IARS	ESHTEFIFTTIKAPLKPYPVsPsDKVLIQEKTQLKGSELEI
P42677	S11	Sugiyama	RPS27 MPS1	__________MPLAKDLLHPsPEEEKRKHKKKRLVQsPNsy
P42858	S1179	GPS6\|SIGNOR\|EPSD\|PSP	HTT HD IT15	VAPGPAIKAALPSLTNPPsLsPIRRKGKEKEPGEQAsVPLs
P42858	S1199	GPS6\|SIGNOR\|EPSD\|PSP\|Sugiyama	HTT HD IT15	sPIRRKGKEKEPGEQAsVPLsPKKGSEASAASRQSDTSGPV
P42858	S432	EPSD\|PSP	HTT HD IT15	GGRsRsGsIVELIAGGGssCsPVLsRKQKGKVLLGEEEALE
P42892	S733	Sugiyama	ECE1	VWCSVRTPESSHEGLITDPHsPsRFRVIGSLSNSKEFSEHF
P42892	S735	Sugiyama	ECE1	CSVRTPESSHEGLITDPHsPsRFRVIGSLSNSKEFSEHFRC
P46087	S732	Sugiyama	NOP2 NOL1 NSUN1	AFLRQNAPPKGTDtQtPAVLsPsKtQAtLKPKDHHQPLGRA
P46087	S786	Sugiyama	NOP2 NOL1 NSUN1	EKAAFQKQNDtPKGPQPPtVsPIRsSRPPPAKRKKsQsRGN
P46777	S172	Sugiyama	RPL5 MSTP030	RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777	S176	Sugiyama	RPL5 MSTP030	GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46782	S142	Sugiyama	RPS5	REDSTRIGRAGTVRRQAVDVsPLRRVNQAIWLLCTGAREAA
P46937	T119	Sugiyama	YAP1 YAP65	PEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQLGAVsP
P46940	S482	Sugiyama	IQGAP1 KIAA0051	LINRALESGDVNTVWKQLsssVtGLTNIEEENCQRYLDELM
P47756	S192	Sugiyama	CAPZB	TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P47756	S204	Sugiyama	CAPZB	sGtMNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKI
P47756	S207	Sugiyama	CAPZB	MNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKIRst
P47989	T222	EPSD\|PSP	XDH XDHA	TPLDPTQEPIFPPELLRLKDtPRKQLRFEGERVTWIQASTL
P48681	T1299	SIGNOR\|iPTMNet	NES Nbla00170	GEEsREEsEEDELGETLPDStPLGFYLRsPtsPRWDPTGEQ
P48681	T315	SIGNOR\|iPTMNet	NES Nbla00170	LSLEVATYRTLLEAENsRLQtPGGGsKtsLsFQDPKLELQF
P48739	S165	Sugiyama	PITPNB	DRSQVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsP
P49023	S244	GPS6\|EPSD\|PSP	PXN	LEssVPsPVPAItVNQGEMssPQRVTsTQQQtRIsAssAtR
P49023	S85	EPSD\|PSP	PXN	PLDQWQPSSSRFIHQQPQsssPVyGssAKtssVsNPQDsVG
P49368	S244	Sugiyama	CCT3 CCTG TRIC5	VTHPRMRRYIKNPRIVLLDssLEyKKGEsQtDIEITREEDF
P49418	S272	GPS6\|SIGNOR\|iPTMNet\|EPSD\|PSP	AMPH AMPH1	SGPLRIAKtPsPPEEPsPLPsPtAsPNHTLAPAsPAPARPR
P49418	S276	GPS6\|SIGNOR\|iPTMNet\|EPSD\|PSP	AMPH AMPH1	RIAKtPsPPEEPsPLPsPtAsPNHTLAPAsPAPARPRsPsQ
P49418	S285	GPS6\|SIGNOR\|iPTMNet\|EPSD\|PSP	AMPH AMPH1	EEPsPLPsPtAsPNHTLAPAsPAPARPRsPsQTRKGPPVPP
P49454	T144	Sugiyama	CENPF	ELERSQQAAQSADVSLNPCNtPQKIFTTPLtPsQYYSGSKY
P49736	S27	Sugiyama	MCM2 BM28 CCNL1 CDCL1 KIAA0030	sFtMAssPAQRRRGNDPLtssPGRssRRtDALtssPGRDLP
P49768	T354	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	PSEN1 AD3 PS1 PSNL1	GGFsEEWEAQRDsHLGPHRstPEsRAAVQELsssILAGEDP
P49792	S2805	Sugiyama	RANBP2 NUP358	VMVPSFCKSEEPDsITKsIssPsVssETMDKPVDLsTRKEI
P49792	S2810	Sugiyama	RANBP2 NUP358	FCKSEEPDsITKsIssPsVssETMDKPVDLsTRKEIDTDST
P49792	T1144	Sugiyama	RANBP2 NUP358	GFRRsDDMFTFHGPGKsVFGtPtLETANKNHEtDGGsAHGD
P50406	S350	SIGNOR\|PSP	HTR6	ALGRFLPCPRCPRERQASLAsPSLRTSHSGPRPGLSLQQVL
P50914	T43	Sugiyama	RPL14	KLVAIVDVIDQNRALVDGPCtQVRRQAMPFKCMQLTDFILK
P50993	S719	Sugiyama	ATP1A2 KIAA0778	VEGCQRQGAIVAVTGDGVNDsPALKKADIGIAMGISGSDVS
P51858	S165	Sugiyama	HDGF HMG1L2	AKEKNEKGALKRRAGDLLEDsPKRPKEAENPEGEEKEAAtL
P52209	S126	Sugiyama	PGD PGDH	YRDTTRRCRDLKAKGILFVGsGVsGGEEGARyGPSLMPGGN
P52272	S633	Sugiyama	HNRNPM HNRPM NAGR1	GGGGAsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKAC
P52272	S637	Sugiyama	HNRNPM HNRPM NAGR1	AsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKACQIFV
P52701	S292	Sugiyama	MSH6 GTBP	EGssDEIssGVGDsESEGLNsPVKVARKRKRMVTGNGsLKR
P52789	S415	Sugiyama	HK2	QRIKENKGEERLRstIGVDGsVyKKHPHFAKRLHKTVRRLV
P53396	S481	Sugiyama	ACLY	ADEVAPAKKAKPAMPQDsVPsPRSLQGKSTTLFSRHTKAIV
P53779	T131	SIGNOR	MAPK10 JNK3 JNK3A PRKM10 SAPK1B	ELVLMKCVNHKNIISLLNVFtPQKTLEEFQDVYLVMELMDA
P54652	S41	Sugiyama	HSPA2	VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652	T38	Sugiyama	HSPA2	CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P54652	T39	Sugiyama	HSPA2	VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P54652	T46	Sugiyama	HSPA2	KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P54652	T48	Sugiyama	HSPA2	EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI
P55081	T267	Sugiyama	MFAP1	ETKKELEENKRsLAALDALNtDDENDEEEyEAWKVRELKRI
P55795	S104	Sugiyama	HNRNPH2 FTP3 HNRPH2	EVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK
P55795	T100	Sugiyama	HNRNPH2 FTP3 HNRPH2	HRyVEVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPF
P55809	S170	Sugiyama	OXCT1 OXCT SCOT	AGVPAFyTPtGyGTLVQEGGsPIKYNKDGSVAIASKPREVR
P55809	S509	Sugiyama	OXCT1 OXCT SCOT	LWEGLTVDDVQKSTGCDFAVsPKLMPMQQIAN_________
P56817	T252	SIGNOR\|EPSD\|PSP	BACE1 BACE KIAA1149	GGSMIIGGIDHSLYTGSLWYtPIRREWYYEVIIVRVEINGQ
P60709	S300	Sugiyama	ACTB	NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P60709	S323	Sugiyama	ACTB	ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709	S368	Sugiyama	ACTB	sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709	S52	Sugiyama	ACTB	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709	S60	Sugiyama	ACTB	HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709	T324	Sugiyama	ACTB	tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709	Y53	Sugiyama	ACTB	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P61254	S32	Sugiyama	RPL26	sKNRKRHFNAPsHIRRKIMssPLSKELRQKYNVRSMPIRKD
P61254	T8	Sugiyama	RPL26	_____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61604	T45	Sugiyama	HSPE1	TVTKGGIMLPEKSQGKVLQAtVVAVGsGsKGKGGEIQPVsV
P61916	S40	Sugiyama	NPC2 HE1	EPVQFKDCGsVDGVIKEVNVsPCPtQPCQLSKGQSYSVNVT
P61978	S284	Sugiyama	HNRNPK HNRPK	MPPGRGGRPMPPSRRDyDDMsPRRGPPPPPPGRGGRGGsRA
P61978	S75	Sugiyama	HNRNPK HNRPK	GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981	S46	Sugiyama	YWHAG	AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P62136	T320	SIGNOR\|EPSD\|PSP	PPP1CA PPP1A	DKNKGKyGQFSGLNPGGRPItPPRNsAKAKK__________
P62195	T109	Sugiyama	PSMC5 SUG1	VHPEGKFVVDVDKNIDINDVtPNCRVALRNDsytLHKILPN
P62249	S9	Sugiyama	RPS16	____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258	S46	Sugiyama	YWHAE	SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263	S139	Sugiyama	RPS14 PRO2640	LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62263	T133	Sugiyama	RPS14 PRO2640	QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__
P62263	T140	Sugiyama	RPS14 PRO2640	ARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL_________
P62273	Y7	Sugiyama	RPS29	______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277	S14	Sugiyama	RPS13	_______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62736	S325	Sugiyama	ACTA2 ACTSA ACTVS GIG46	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736	S54	Sugiyama	ACTA2 ACTSA ACTVS GIG46	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736	S62	Sugiyama	ACTA2 ACTSA ACTVS GIG46	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736	T326	Sugiyama	ACTA2 ACTSA ACTVS GIG46	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736	Y55	Sugiyama	ACTA2 ACTSA ACTVS GIG46	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62750	S43	Sugiyama	RPL23A	KAKKAVLKGVHSHKKKKIRtsPTFRRPKTLRLRRQPKYPRK
P62750	T42	Sugiyama	RPL23A	LKAKKAVLKGVHSHKKKKIRtsPTFRRPKTLRLRRQPKYPR
P62826	T66	Sugiyama	RAN ARA24 OK/SW-cl.81	EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62942	S9	Sugiyama	FKBP1A FKBP1 FKBP12	____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG
P63104	S45	Sugiyama	YWHAZ	CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63261	S300	Sugiyama	ACTG1 ACTG	NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P63261	S323	Sugiyama	ACTG1 ACTG	ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261	S368	Sugiyama	ACTG1 ACTG	sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261	S52	Sugiyama	ACTG1 ACTG	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261	S60	Sugiyama	ACTG1 ACTG	HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261	T324	Sugiyama	ACTG1 ACTG	tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261	Y53	Sugiyama	ACTG1 ACTG	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267	S324	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267	S53	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267	S61	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267	T325	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267	Y54	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809	S102	Sugiyama	YBX1 NSEP1 YB1	EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P68032	S325	Sugiyama	ACTC1 ACTC	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032	S54	Sugiyama	ACTC1 ACTC	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032	S62	Sugiyama	ACTC1 ACTC	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032	T326	Sugiyama	ACTC1 ACTC	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032	Y55	Sugiyama	ACTC1 ACTC	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104	T432	Sugiyama	EEF1A1 EEF1A EF1A LENG7	VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133	S325	Sugiyama	ACTA1 ACTA	TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133	S54	Sugiyama	ACTA1 ACTA	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133	S62	Sugiyama	ACTA1 ACTA	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133	T326	Sugiyama	ACTA1 ACTA	TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133	Y55	Sugiyama	ACTA1 ACTA	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363	T56	Sugiyama	TUBA1B	MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
P85037	S420	Sugiyama	FOXK1 MNF	RGVSCFRtPFGPLssRsAPAsPtHPGLMsPRsGGLQtPECL
P85037	S428	Sugiyama	FOXK1 MNF	PFGPLssRsAPAsPtHPGLMsPRsGGLQtPECLsREGsPIP
P85037	T422	Sugiyama	FOXK1 MNF	VSCFRtPFGPLssRsAPAsPtHPGLMsPRsGGLQtPECLsR
Q00535	S47	PSP	CDK5 CDKN5 PSSALRE	HEIVALKRVRLDDDDEGVPSsALREICLLKELKHKNIVRLH
Q00535	T17	Sugiyama	CDK5 CDKN5 PSSALRE	____MQKYEKLEKIGEGtyGtVFKAKNRETHEIVALKRVRL
Q01082	S2138	Sugiyama	SPTBN1 SPTB2	QWDtsKGEQVsQNGLPAEQGsPRMAETVDTsEMVNGAtEQR
Q01105	S161	Sugiyama	SET	FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01105	S166	Sugiyama	SET	yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT
Q01105	S168	Sugiyama	SET	ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q02078	S408	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MEF2A MEF2	QGSNLSINTNQNISIKSEPIsPPRDRMTPSGFQQQQQQQQQ
Q02750	T286	SIGNOR	MAP2K1 MEK1 PRKMK1	PDAKELELMFGCQVEGDAAEtPPRPRtPGRPLssyGMDsRP
Q02750	T292	EPSD\|PSP	MAP2K1 MEK1 PRKMK1	ELMFGCQVEGDAAEtPPRPRtPGRPLssyGMDsRPPMAIFE
Q04637	S1231	Sugiyama	EIF4G1 EIF4F EIF4G EIF4GI	tEDRDRGRDAVKREAALPPVsPLKAALsEEELEKKsKAIIE
Q04917	S46	Sugiyama	YWHAH YWHA1	AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05193	S774	SIGNOR\|iPTMNet	DNM1 DNM	MPPPVDDSWLQVQSVPAGRRsPTSsPtPQRRAPAVPPARPG
Q05193	S778	SIGNOR\|iPTMNet	DNM1 DNM	VDDSWLQVQSVPAGRRsPTSsPtPQRRAPAVPPARPGsRGP
Q05193	T780	EPSD\|PSP	DNM1 DNM	DSWLQVQSVPAGRRsPTSsPtPQRRAPAVPPARPGsRGPAP
Q05397	S732	GPS6\|SIGNOR\|EPSD	PTK2 FAK FAK1	PPKPsRPGYPsPRSSEGFYPsPQHMVQTNHyQVSGYPGSHG
Q05397	S910	EPSD\|PSP	PTK2 FAK FAK1	sLssPADsyNEGVKLQPQEIsPPPtANLDRSNDKVyENVTG
Q05639	T432	Sugiyama	EEF1A2 EEF1AL STN	VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q05682	T730	Sugiyama	CALD1 CAD CDM	RNIKsMWEKGNVFssPtAAGtPNKEtAGLKVGVSsRINEWL
Q06413	S396	GPS6\|EPSD	MEF2C	QSSNLSLPSTQsLNIKSEPVsPPRDRTTtPSRYPQHTRHEA
Q06830	T166	Sugiyama	PRDX1 PAGA PAGB TDPX2	DLPVGRsVDEtLRLVQAFQFtDKHGEVCPAGWKPGsDtIKP
Q07666	S35	Sugiyama	KHDRBS1 SAM68	sGRsGsMDPsGAHPsVRQtPsRQPPLPHRSRGGGGGSRGGA
Q07666	T33	Sugiyama	KHDRBS1 SAM68	RssGRsGsMDPsGAHPsVRQtPsRQPPLPHRSRGGGGGSRG
Q07820	T92	EPSD\|PSP	MCL1 BCL2L3	DSRRVARPPPIGAEVPDVTAtPARLLFFAPTRRAAPLEEME
Q08AD1	S1319	Sugiyama	CAMSAP2 CAMSAP1L1 KIAA1078	NEsVHsGKRtPRsEsVEGFLsPsRCGsRNGEKDWENAstts
Q09666	S177	Sugiyama	AHNAK PM227	VtAytVDVTGREGAKDIDIssPEFKIKIPRHELtEISNVDV
Q09666	S41	Sugiyama	AHNAK PM227	HGLTIAQRDDGVFVQEVtQNsPAARTGVVKEGDQIVGATIy
Q12778	S249	EPSD\|PSP	FOXO1 FKHR FOXO1A	EGTGKssWWMLNPEGGKSGKsPRRRAAsMDNNSKFAKSRSR
Q12802	S2728	Sugiyama	AKAP13 BRX HT31 LBC	PsPsAPSIAKsGsLDsELsVsPKRNsISRTHKDKGPFHILS
Q12879	S1232	SIGNOR\|iPTMNet	GRIN2A NMDAR2A	THCRSCLSNMPTYSGHFTMRsPFKCDACLRMGNLyDIDEDQ
Q12931	S511	Sugiyama	TRAP1 HSP75 HSPC5	RAGtRNIyyLCAPNRHLAEHsPyyEAMKKKDTEVLFCFEQF
Q12931	S568	Sugiyama	TRAP1 HSP75 HSPC5	ISVETDIVVDHYKEEKFEDRsPAAECLSEKETEELMAWMRN
Q13033	S229	Sugiyama	STRN3 GS2NA SG2NA	SEPNGsVETKNLEQILNGGEsPKQKGQEIKRSSGDVLETFN
Q13045	S856	Sugiyama	FLII FLIL	KNWDDVLTVDYTRNAEAVLQsPGLsGKVKRDAEKKDQMKAD
Q13136	T701	EPSD\|PSP	PPFIA1 LIP1	IPPYPAssLAsssPPGsGRstPRRIPHsPAREVDRLGVMTL
Q13153	T212	SIGNOR\|iPTMNet	PAK1	PRPEHTKsVytRsVIEPLPVtPtRDVAtsPIsPtENNttPP
Q13200	S16	Sugiyama	PSMD2 TRAP2	_____MEEGGRDKAPVQPQQsPAAAPGGtDEKPsGKERRDA
Q13242	S211	Sugiyama	SRSF9 SFRS9 SRP30C	GYsRsRSGsRGRDsPyQsRGsPHyFsPFRPy__________
Q13283	S231	Sugiyama	G3BP1 G3BP	QEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsW
Q13283	S232	Sugiyama	G3BP1 G3BP	EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA
Q13303	S31	PSP	KCNAB2 KCNA2B KCNK2	ARLsLRQtGsPGMIystRYGsPKRQLQFYRNLGKSGLRVSC
Q13315	S794	SIGNOR\|EPSD\|PSP	ATM	GSLRNMMQLCTRCLSNCTKKsPNKIASGFFLRLLTSKLMND
Q13428	T983	Sugiyama	TCOF1	DPNRsPAGPAAtPAQAQAAstPRKARASESTARssssEsED
Q13439	T31	Sugiyama	GOLGA4	EEQQQLQQALAPAQAssNsstPtRMRsRtssFtEQLDEGtP
Q13509	S115	Sugiyama	TUBB3 TUBB4	SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509	S75	Sugiyama	TUBB3 TUBB4	SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13522	S67	SIGNOR	PPP1R1A IPP1	sPEIDEDRIPNPHLKSTLAMsPRQRKKMtRITPTMKELQMM
Q13573	S224	Sugiyama	SNW1 SKIIP SKIP	KDPMEPPRFKINKKIPRGPPsPPAPVMHsPsRKMTVKEQQE
Q13573	S232	Sugiyama	SNW1 SKIIP SKIP	FKINKKIPRGPPsPPAPVMHsPsRKMTVKEQQEWKIPPCIS
Q13573	S234	Sugiyama	SNW1 SKIIP SKIP	INKKIPRGPPsPPAPVMHsPsRKMTVKEQQEWKIPPCISNW
Q13765	S186	Sugiyama	NACA HSD48	sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI
Q13765	S191	Sugiyama	NACA HSD48	VDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDIVNAIM
Q13794	S13	SIGNOR\|EPSD\|PSP	PMAIP1 NOXA	________MPGKKARKNAQPsPARAPAELEVECATQLRRFG
Q13884	S87	Sugiyama	SNTB1 SNT2B1	SFCRGAGAGHPGAGGAQPPDsPAGVRTAFTDLPEQVPESIS
Q13885	S115	Sugiyama	TUBB2A TUBB2	sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885	S75	Sugiyama	TUBB2A TUBB2	AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q14141	S408	Sugiyama	SEPTIN6 KIAA0128 SEP2 SEPT6	sLDDEVNAFKQRKTAAELLQsQGsQAGGsQtLKRDKEKKNN
Q14141	S416	Sugiyama	SEPTIN6 KIAA0128 SEP2 SEPT6	FKQRKTAAELLQsQGsQAGGsQtLKRDKEKKNNPWLCTE__
Q14157	S416	Sugiyama	UBAP2L KIAA0144 NICE4	tQsPsLVQYDLKNPsDsAVHsPFtKRQAFtPsstMMEVFLQ
Q14157	S609	Sugiyama	UBAP2L KIAA0144 NICE4	GPLYEQRSTQTRRyPssIsssPQKDLtQAKNGFSSVQATQL
Q14157	T256	Sugiyama	UBAP2L KIAA0144 NICE4	AWRtAtEEWGtEDWNEDLsEtKIFtAsNVssVPLPAENVtI
Q14194	S522	SIGNOR\|EPSD\|PSP	CRMP1 DPYSL1 ULIP3	PVyEVPAtPKYAtPAPsAKssPsKHQPPPIRNLHQSNFsLs
Q14194	T509	SIGNOR\|EPSD\|PSP	CRMP1 DPYSL1 ULIP3	FGLQGVSRGMYDGPVyEVPAtPKYAtPAPsAKssPsKHQPP
Q14195	S518	SIGNOR	DPYSL3 CRMP4 DRP3 ULIP ULIP1	MYDGPVFDLtttPKGGtPAGsARGsPTRPNPPVRNLHQSGF
Q14195	S522	EPSD\|PSP	DPYSL3 CRMP4 DRP3 ULIP ULIP1	PVFDLtttPKGGtPAGsARGsPTRPNPPVRNLHQSGFSLSG
Q14195	T509	SIGNOR	DPYSL3 CRMP4 DRP3 ULIP ULIP1	ADLHAVPRGMYDGPVFDLtttPKGGtPAGsARGsPTRPNPP
Q14195	T514	SIGNOR	DPYSL3 CRMP4 DRP3 ULIP ULIP1	VPRGMYDGPVFDLtttPKGGtPAGsARGsPTRPNPPVRNLH
Q14204	S2410	Sugiyama	DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325	GEDEAQRRRKGKEDEGEEAAsPMLQIQRDAATIMQPYFTSN
Q14247	S405	Sugiyama	CTTN EMS1	EEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVyEDAA
Q14247	S418	Sugiyama	CTTN EMS1	KtQtPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVs
Q14247	T145	GPS6	CTTN EMS1	FGVQMDRVDQsAVGFEyQGKtEKHAsQKDyssGFGGKyGVQ
Q14247	T219	GPS6	CTTN EMS1	yGIDKDKVDKsAVGFEyQGKtEKHESQKDyVKGFGGKFGVQ
Q14676	S793	Sugiyama	MDC1 KIAA0170 NFBD1	EAyGPCLsPPRAIPGDQHPEsPVHtEPMGIQGRGRQTVDKV
Q14697	S58	Sugiyama	GANAB G2AN KIAA0088	FKtCEEssFCKRQRsIRPGLsPyRALLDSLQLGPDSLTVHL
Q14814	S444	EPSD\|PSP	MEF2D	VGAALTVTTHPHISIKSEPVsPSRERsPAPPPPAVFPAARP
Q14847	T104	Sugiyama	LASP1 MLN50	VRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsNIKyHE
Q14980	S1757	Sugiyama	NUMA1 NMP22 NUMA	ITSKLPRtQPDGtsVPGEPAsPIsQRLPPKVEsLEsLyFtP
Q14980	T2000	Sugiyama	NUMA1 NMP22 NUMA	GITTRQQRKRVsLEPHQGPGtPEsKKATSCFPRPMtPRDRH
Q14C86	S466	Sugiyama	GAPVD1 GAPEX5 KIAA1521 RAP6	PAKPGKSSSLEMTPyNTPQLsPATTPANKKNRLPIATRSRS
Q14C86	Y460	Sugiyama	GAPVD1 GAPEX5 KIAA1521 RAP6	LLANLPPAKPGKSSSLEMTPyNTPQLsPATTPANKKNRLPI
Q15003	S81	Sugiyama	NCAPH BRRN BRRN1 CAPH KIAA0074	EKERLQRRRsRVFDLQFstDsPRLLAsPsSRsIDIsATIPK
Q15067	S26	Sugiyama	ACOX1 ACOX	RRERDSASFNPELLtHILDGsPEKtRRRREIENMILNDPDF
Q15078	S135	Sugiyama	CDK5R1 CDK5R NCK5A	SGSQTGGSSSVKKAPHPAVtsAGtPKRVIVQASTSELLRCL
Q15078	S8	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CDK5R1 CDK5R NCK5A	_____________MGTVLSLsPSyRKATLFEDGAATVGHYT
Q15078	T134	Sugiyama	CDK5R1 CDK5R NCK5A	LSGSQTGGSSSVKKAPHPAVtsAGtPKRVIVQASTSELLRC
Q15078	T138	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP\|Sugiyama	CDK5R1 CDK5R NCK5A	QTGGSSSVKKAPHPAVtsAGtPKRVIVQASTSELLRCLGEF
Q15154	S69	Sugiyama	PCM1	KKKFGVESDKRVTNDISPESsPGVGRRRTKTPHTFPHSRYM
Q15293	T76	Sugiyama	RCN1 RCN	FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD
Q15642	T302	Sugiyama	TRIP10 CIP4 STOT STP	VEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRTKRWP
Q15717	S202	EPSD\|PSP	ELAVL1 HUR	KFAANPNQNKNVALLsQLyHsPARRFGGPVHHQAQRFRFsP
Q15773	S238	Sugiyama	MLF2	GAGGRRAEGPPRLAIQGPEDsPsRQsRRYDW__________
Q15833	T572	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	STXBP2 UNC18B	EVTRATEGKWEVLIGSSHILtPTRFLDDLKALDKKLEDIAL
Q15853	S155	GPS6\|PSP	USF2 BHLHB12	PGPAAPFPLAVIQNPFSNGGsPAAEAVSGEARFAYFPASSV
Q15853	S222	GPS6\|PSP	USF2 BHLHB12	PQDVLQTGTQRTIAPRTHPYsPKIDGTRtPRDERRRAQHNE
Q16204	S244	Sugiyama	CCDC6 D10S170 TST1	LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF
Q16236	S433	EPSD\|PSP	NFE2L2 NRF2	QSTHVHDAQCENTPEKELPVsPGHRKtPFTKDKHSSRLEAH
Q16236	T395	EPSD\|PSP	NFE2L2 NRF2	DSEVEELDSAPGSVKQNGPKtPVHSSGDMVQPLsPSQGQST
Q16236	T439	EPSD\|PSP	NFE2L2 NRF2	DAQCENTPEKELPVsPGHRKtPFTKDKHSSRLEAHLTRDEL
Q16555	S522	SIGNOR\|EPSD\|PSP	DPYSL2 CRMP2 ULIP2	PVCEVsVtPKtVtPAssAKtsPAKQQAPPVRNLHQsGFsLs
Q16595	S158	Sugiyama	FXN FRDA X25	GDLGTYVINKQTPNKQIWLSsPSSGPKRYDWTGKNWVYSHD
Q16630	T157	Sugiyama	CPSF6 CFIM68	SKKLMDLLPKRELHGQNPVVtPCNKQFLsQFEMQSRKTTQS
Q16643	S142	EPSD\|PSP	DBN1 D0S117E	EDIDAGAIGQRLsNGLARLssPVLHRLRLREDENAEPVGtt
Q16665	S687	EPSD\|PSP	HIF1A BHLHE78 MOP1 PASD8	AsPNRAGKGVIEQTEKSHPRsPNVLsVALsQRTtVPEEELN
Q16762	S38	Sugiyama	TST	ESIRTGKLGPGLRVLDAsWysPGTREARKEYLERHVPGASF
Q16881	T413	Sugiyama	TXNRD1 GRIM12 KDRF	HGIKFIRQFVPIKVEQIEAGtPGRLRVVAQSTNSEEIIEGE
Q3V6T2	S1675	EPSD\|PSP	CCDC88A APE GRDN KIAA1212	VLQHKISETLESRHHKIKtGsPGsEVVTLQQFLEEsNKLTS
Q4KMP7	T152	Sugiyama	TBC1D10B FP2461	sPKtEEARPsPAPGPGtPtGtPtRtPsRtAPGALTAKPPLA
Q4KMP7	T154	Sugiyama	TBC1D10B FP2461	KtEEARPsPAPGPGtPtGtPtRtPsRtAPGALTAKPPLAPK
Q4KMP7	T156	Sugiyama	TBC1D10B FP2461	EEARPsPAPGPGtPtGtPtRtPsRtAPGALTAKPPLAPKPG
Q4V328	S655	Sugiyama	GRIPAP1 KIAA1167	ILTNSKSRSGLEELVLsEMNsPSRtQtGDsssIssFsYREI
Q53EL6	S94	Sugiyama	PDCD4 H731	GDsVsDsGsDALRSGLtVPtsPKGRLLDRRSRSGKGRGLPK
Q58FF7	S370	Sugiyama	HSP90AB3P HSP90BC	KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q5JSH3	S96	Sugiyama	WDR44 RPH11	QLEDDsLDSKGKELsDQAtAsPIVARTDLSNIPGLLAIDQV
Q5S007	S1627	EPSD\|PSP	LRRK2 PARK8	MAQILtVKVEGCPKHPKGIIsRRDVEKFLSKKRKFPKNYMs
Q5T200	S879	Sugiyama	ZC3H13 KIAA0853	EKHRLLsQVVRPQEsRsLsPsHLTEDRQGRWKEEDRKPERK
Q5T4S7	S181	Sugiyama	UBR4 KIAA0462 KIAA1307 RBAF600	PQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLTSVF
Q5VT52	S965	Sugiyama	RPRD2 KIAA0460 HSPC099	NsLsQsttGHLSLPQKQyPDsPHPVPHRsLFsPQNtLAAPT
Q5VTE0	T432	Sugiyama	EEF1A1P5 EEF1AL3	VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q5VV41	S191	Sugiyama	ARHGEF16 EPHEXIN4 NBR	IQLsPKLQALAEEPsQPHtRsPAKNKKTLGRKRGHKGsFKD
Q69YN4	S1579	Sugiyama	VIRMA KIAA1429 MSTP054	CCSDFDLHSELERsFLsEPssPGRtKTTKGFKLGKHKHETF
Q6H8Q1	S296	Sugiyama	ABLIM2 KIAA1808	tRtssEsIIsVPAsstsGsPsRVIYAKLGGEILDYRDLAAL
Q6KC79	S350	Sugiyama	NIPBL IDN3 SCC2	KLGKDEKEQSEKAAMyDIIssPsKDSTKLTLRLSRVRssDM
Q6P1L8	S49	Sugiyama	MRPL14 MRPL32 RPML32	LSAIQKMTRVRVVDNSALGNsPyHRAPRCIHVYKKNGVGKV
Q6PEY2	T56	Sugiyama	TUBA3E	MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
Q6PID6	S197	Sugiyama	TTC33	QQKVAQRIKKSEAPAEVtHFsPKSIPDYDFESDEIVAVCAA
Q6PKG0	S774	Sugiyama	LARP1 KIAA0731 LARP	LFGAPEPstIARsLPttVPEsPNyRNtRtPRtPRtPQLKDS
Q6S8J3	S1068	Sugiyama	POTEE A26C1A POTE2	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6VN20	S365	Sugiyama	RANBP10 KIAA1464	DSEVRSLSSRsPKsQDsyPGsPsLsPRHGPsssHMHNTGAD
Q6VN20	S369	Sugiyama	RANBP10 KIAA1464	RSLSSRsPKsQDsyPGsPsLsPRHGPsssHMHNTGADsPsC
Q6ZN18	S24	Sugiyama	AEBP2	AItDMADLEELsRLsPLPPGsPGsAARGRAEPPEEEEEEEE
Q71RC2	S594	Sugiyama	LARP4 PP13296	GLNQttIPVsPPsttKPsRAstAsPCNNNINAAtAVALQEP
Q71U36	T56	Sugiyama	TUBA1A TUBA3	MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q7KZI7	S619	Sugiyama	MARK2 EMK1	AGQLRQVRDQQNLPyGVtPAsPsGHsQGRRGAsGsIFSKFT
Q7Z5J4	S345	Sugiyama	RAI1 KIAA1820	DAAVRTPEQyyQtFsPsssHsPARSVGRSPSYSSTPSPLMP
Q7Z5K2	S226	Sugiyama	WAPL FOE KIAA0261 WAPAL	ETNDTWNSQFGKRPEsPsEIsPIKGsVRTGLFEWDNDFEDI
Q7Z6M1	S137	Sugiyama	RABEPK RAB9P40	QVLNPETRTWTTPEVtsPPPsPRTFHTSSAAIGNQLYVFGG
Q86TN4	S240	Sugiyama	TRPT1	LRPTRKPLSLAGDEEtECQssPKHssRERRRIQQ_______
Q86VM9	S613	Sugiyama	ZC3H18 NHN1	SGSRSRsRsFsssPsPsPtPsPHRPsIRTKGEPAPPPGKAG
Q86VM9	S618	Sugiyama	ZC3H18 NHN1	RsRsFsssPsPsPtPsPHRPsIRTKGEPAPPPGKAGEKSVK
Q86VM9	T611	Sugiyama	ZC3H18 NHN1	SFSGSRSRsRsFsssPsPsPtPsPHRPsIRTKGEPAPPPGK
Q86VP6	S376	Sugiyama	CAND1 KIAA0829 TIP120 TIP120A	CLDAVVSTRHEMLPEFyKTVsPALISRFKEREENVKADVFH
Q86YP4	S114	Sugiyama	GATAD2A	SERRPPsPDVIVLsDNEQPssPRVNGLttVALKETSTEALM
Q8IV63	S108	SIGNOR\|PSP	VRK3	TLSSSERSKGSGSRPPtPKSsPQKTRKsPQVtRGsPQKTsC
Q8IVD9	S340	Sugiyama	NUDCD3 KIAA1068	PQSHELKVHEMLKKGWDAEGsPFRGQRFDPAMFNIsPGAVQ
Q8IWR1	S308	SIGNOR\|PSP	TRIM59 RNF104 TRIM57 TSBF1	EWSRTEIGQIKNVLIPKMKIsPKRMSCSWPGKDEKEVEFLK
Q8IWU2	S1450	SIGNOR\|EPSD\|PSP	LMTK2 AATYK2 BREK KIAA1079 KPI2 LMR2	SKTTSNLLSSKPSLQTSKYFsPPPPARSTEQSWPHSAPySR
Q8IWW6	S450	Sugiyama	ARHGAP12	NDKESPTASKPCFPENESSPsSPKHQDTASSPKDQEKyGLL
Q8IXQ3	S67	Sugiyama	C9orf40	LGVPEQHRKRKIDAGTMAEPsAsPsKRRDsGDNsAPsGQER
Q8N556	S265	Sugiyama	AFAP1 AFAP	KEAYSGCSGPVDSECPPPPssPVHKAELEKKLssERPssDG
Q8N556	S668	Sugiyama	AFAP1 AFAP	AGGVTLGLAIEPKsGtssPQsPVFRHRtLENsPIssCDtsD
Q8NBJ5	S612	Sugiyama	COLGALT1 GLT25D1 PSEC0241	QKMREQQALSREAKNsDVLQsPLDsAARDEL__________
Q8NBJ7	S264	Sugiyama	SUMF2 PSEC0171 UNQ1968/PRO4500	AAEQDMRVLRGAsWIDtADGsANHRARVttRMGNtPDsAsD
Q8NEB9	T159	SIGNOR\|EPSD\|PSP	PIK3C3 VPS34	GMHDLKVWPNVEADGSEPTKtPGRTsSTLSEDQMSRLAKLT
Q8NEB9	T668	SIGNOR\|EPSD\|PSP	PIK3C3 VPS34	LQIISLMDKLLRKENLDLKLtPYKVLATSTKHGFMQFIQSV
Q8NEL9	S11	PSP	DDHD1 KIAA1705	__________MNyPGRGsPRsPEHNGRGGGGGAWELGSDAR
Q8NEL9	S727	PSP	DDHD1 KIAA1705	KEPtsVSENEGIstIPsPVtsPVLsRRHYGESITNIGKASI
Q8NEN9	S519	Sugiyama	PDZD8 PDZK8	EDLAsDVRAQNEFKDEAQsLsHsPKRVPtTLsIKPLGAIsP
Q8NEN9	S521	Sugiyama	PDZD8 PDZK8	LAsDVRAQNEFKDEAQsLsHsPKRVPtTLsIKPLGAIsPVL
Q8NEN9	S989	Sugiyama	PDZD8 PDZK8	KHtPNtsDNEGsDtEVCGPNsPsKRGNSTGIKLVRKEGGLD
Q8NEZ5	S160	PSP	FBXO22 FBX22	PKQCQVLGIVTPGIVVTPMGsGsNRPQEIEIGESGFALLFP
Q8NEZ5	S162	PSP	FBXO22 FBX22	QCQVLGIVTPGIVVTPMGsGsNRPQEIEIGESGFALLFPQI
Q8NFD5	S1744	Sugiyama	ARID1B BAF250B DAN15 KIAA1235 OSA2	ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI
Q8TBN0	T181	Sugiyama	RAB3IL1	VItstPAsPNRELHPQLLsPtKAGPRKGHSRHKstsstLCP
Q8TCS8	S754	Sugiyama	PNPT1 PNPASE	KYFGRDPADGRMRLSRKVLQsPAtTVVRTLNDRssIVMGEP
Q8TD19	S868	Sugiyama	NEK9 KIAA1995 NEK8 NERCC	LQGLKVAsEAPLEHKPQVEAssPRLNPAVtCAGKGtPLtPP
Q8TDN4	S313	SIGNOR	CABLES1 CABLES	EtLEDIEENAPLRRCRtLSGsPRPKNFKKIHFIKNMRQHDT
Q8TEQ6	S648	Sugiyama	GEMIN5	ITEPYRTLSGHTAKITsVAWsPHHDGRLVSASYDGTAQVWD
Q8TEW0	S728	Sugiyama	PARD3 PAR3 PAR3A	DDRERRIsHsLysGIEGLDEsPsRNAALsRIMGESGKYQLS
Q8WVM8	S303	Sugiyama	SCFD1 C14orf163 KIAA0917 STXBP1L2 FKSG23	DVLDFHLNRVNLEEssGVENsPAGARPKRKNKKsYDLtPVD
Q8WVV9	S75	Sugiyama	HNRNPLL HNRPLL SRRF BLOCK24	GGGRsFsQPEAGGsHHKVsVsPVVHVRGLCEsVVEADLVEA
Q8WWM7	S111	Sugiyama	ATXN2L A2D A2LG A2LP A2RP	PGAAAIGsARGQstGKGPPQsPVFEGVyNNSRMLHFLTAVV
Q8WX93	S484	Sugiyama	PALLD KIAA0992 CGI-151	VRGAPPLQVQWFRQGsEIQDsPDFRILQKKPRSTAEPEEIC
Q8WXG6	S1270	Sugiyama	MADD DENN IG20 KIAA0358	STIFGKAHSLKPSIKEKLAGsPIRTSEDVSQRVYLYEGLLG
Q8WYQ5	S95	Sugiyama	DGCR8 C22orf12 DGCRK6 LP4941	LSKGSFSKGRLLIDPNCsGHsPRTARHAPAVRKFSPDLKLL
Q92530	S153	Sugiyama	PSMF1	RIVSGIITPIHEQWEKANVssPHREFPPAtAREVDPLRIPP
Q92558	S310	iPTMNet	WASF1 KIAA0269 SCAR1 WAVE1	AKPIPTCISsAtGLIENRPQsPAtGRTPVFVsPtPPPPPPP
Q92558	S397	iPTMNet	WASF1 KIAA0269 SCAR1 WAVE1	IAPGVLHPAPPPIAPPLVQPsPPVARAAPVCETVPVHPLPQ
Q92558	S441	iPTMNet	WASF1 KIAA0269 SCAR1 WAVE1	QGLPPPPPPPPLPPPGIRPSsPVTVTALAHPPSGLHPTPST
Q92576	S1614	Sugiyama	PHF3 KIAA0244	KRQLQEDQENNLQDNQtsNssPCRsNVGKGNIDGNVsCsEN
Q969H0	S349	GPS6	FBXW7 FBW7 FBX30 SEL10	GIDEPLHIKRRKVIKPGFIHsPWKSAYIRQHRIDTNWRRGE
Q969H0	S372	GPS6	FBXW7 FBW7 FBX30 SEL10	KSAYIRQHRIDTNWRRGELKsPKVLKGHDDHVITCLQFCGN
Q96AC1	T416	Sugiyama	FERMT2 KIND2 MIG2 PLEKHC1	WCTFKDTSISCYKSKEESsGtPAHQMNLRGCEVTPDVNISG
Q96BY7	S1583	Sugiyama	ATG2B C14orf103	KDFGIVPPTSPAKsYIsPHssPsHtPTRHGRNTVCGGKGRN
Q96BY7	S1585	Sugiyama	ATG2B C14orf103	FGIVPPTSPAKsYIsPHssPsHtPTRHGRNTVCGGKGRNHD
Q96C19	S74	PSP\|Sugiyama	EFHD2 SWS1	ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI
Q96C19	S76	Sugiyama	EFHD2 SWS1	SAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQIKD
Q96DX5	S201	Sugiyama	ASB9	ACVKKLLESGADVNQGKGQDsPLHAVARTASEELACLLMDF
Q96G46	T99	Sugiyama	DUS3L	DGQtADGQtEEAAEPGEQLQtQKRARGQNKGRPHVKPTNYD
Q96KR7	S318	SIGNOR\|EPSD\|PSP	PHACTR3 C20orf101 SCAPIN1	HRALATKHRQDSFQGRESKGsPKKRLDVRLSRTSSVERGKE
Q96MH2	S76	Sugiyama	HEXIM2 L3	EDLAGAVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPS
Q96QB1	S557	SIGNOR\|PSP	DLC1 ARHGAP7 KIAA1723 STARD12	KWTFQRDSKRWsRLEEFDVFsPKQDLVPGsPDDSHPKDGPs
Q96QB1	S642	SIGNOR\|PSP	DLC1 ARHGAP7 KIAA1723 STARD12	ISVCSSSNLAGNDDSFGSLPsPKELSSFSFSMKGHEKTAKS
Q96QB1	S859	SIGNOR\|PSP	DLC1 ARHGAP7 KIAA1723 STARD12	RtGsFHGPGHISLRRENSSDsPKELKRRNsSSSMSSRLSIY
Q96QB1	S946	SIGNOR\|PSP	DLC1 ARHGAP7 KIAA1723 STARD12	KFSDEGDSDSALDSVSPCPssPKQIHLDVDNDRTTPSDLDS
Q96RR4	S129	SIGNOR	CAMKK2 CAMKKB KIAA0787	LAAGGsLDMNGRCICPsLPysPVssPQssPRLPRRPTVESH
Q96RR4	S133	SIGNOR	CAMKK2 CAMKKB KIAA0787	GsLDMNGRCICPsLPysPVssPQssPRLPRRPTVESHHVSI
Q96RR4	S137	SIGNOR	CAMKK2 CAMKKB KIAA0787	MNGRCICPsLPysPVssPQssPRLPRRPTVESHHVSITGMQ
Q99459	T385	Sugiyama	CDC5L KIAA0432 PCDC5RP	EAQNLMALtNVDtPLKGGLNtPLHEsDFsGVtPQRQVVQtP
Q99459	T396	Sugiyama	CDC5L KIAA0432 PCDC5RP	DtPLKGGLNtPLHEsDFsGVtPQRQVVQtPNtVLstPFRtP
Q99460	T311	Sugiyama	PSMD1	EKDsDsMEtEEKTSsAFVGKtPEAsPEPKDQTLKMIKILSG
Q99490	S279	SIGNOR	AGAP2 CENTG1 KIAA0167	GAGARGKLSPRKGKSKTLDNsDLHPGPPAGSPPPLTLPPTP
Q9BQ52	S199	Sugiyama	ELAC2 HPC2	TVyQIPIHSEQRRGKHQPWQsPERPLsRLsPERssDsEsNE
Q9BQE3	S439	Sugiyama	TUBA1C TUBA6	SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BQE3	T56	Sugiyama	TUBA1C TUBA6	MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q9BQE9	S122	Sugiyama	BCL7B	QLKVDsstNssPsPQQsEsLsPAHtsDFRtDDsQPPTLGQE
Q9BQG0	S11	Sugiyama	MYBBP1A P160	__________MEsRDPAQPMsPGEAtQsGARPADRYGLLKH
Q9BQG0	S1166	Sugiyama	MYBBP1A P160	RPKLEKKDAKEIPsAtQsPIsKKRKKKGFLPETKKRKKRKs
Q9BRP1	S20	Sugiyama	PDCD2L	_MAAVLKPVLLGLRDAPVHGsPTGPGAWTASKLGGIPDALP
Q9BTC0	S1030	Sugiyama	DIDO1 C20orf158 DATF1 KIAA0333	KSILAKPsssPDPRYLsVPPsPNIstsEsRsPPEGDtTLFL
Q9BTU6	S51	Sugiyama	PI4K2A	VPGGAVRVAAAAGsGPsPPGsPGHDRERQPLLDRARGAAAQ
Q9BVA1	S115	Sugiyama	TUBB2B	sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1	S75	Sugiyama	TUBB2B	tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BX68	T47	Sugiyama	HINT2	QVRGAAGVTDGNEVAKAQQAtPGGAAPtIFsRILDKsLPAD
Q9BXB4	S181	Sugiyama	OSBPL11 ORP11 OSBP12	IGKNNPPLKsRsFsLAsssNsPIsQRRPsQNAIsFFNVGHS
Q9BYX7	S368	Sugiyama	POTEKP ACTBL3 FKSG30	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9C0C2	S435	Sugiyama	TNKS1BP1 KIAA1741 TAB182	DAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAALPQGQG
Q9GZM8	S198	SIGNOR\|iPTMNet	NDEL1 EOPA MITAP1 NUDEL	RQELAVRERQQEVTRKsAPssPTLDCEKMDSAVQAsLsLPA
Q9GZM8	S231	SIGNOR\|iPTMNet	NDEL1 EOPA MITAP1 NUDEL	QAsLsLPAtPVGKGTENTFPsPKAIPNGFGTsPLtPSARIs
Q9GZM8	S242	SIGNOR\|iPTMNet	NDEL1 EOPA MITAP1 NUDEL	GKGTENTFPsPKAIPNGFGTsPLtPSARIsALNIVGDLLRK
Q9GZM8	T219	SIGNOR\|iPTMNet	NDEL1 EOPA MITAP1 NUDEL	PTLDCEKMDSAVQAsLsLPAtPVGKGTENTFPsPKAIPNGF
Q9GZM8	T245	iPTMNet	NDEL1 EOPA MITAP1 NUDEL	TENTFPsPKAIPNGFGTsPLtPSARIsALNIVGDLLRKVGA
Q9GZT9	S125	Sugiyama	EGLN1 C1orf12 PNAS-118 PNAS-137	GDAAKGKVKAKPPADPAAAAsPCRAAAGGQGsAVAAEAEPG
Q9H0E9	T77	Sugiyama	BRD8 SMAP SMAP2	DWFSQKHCASQYSELLEttEtPKRKRGEKGEVVETVEDVIV
Q9H2C0	S52	Sugiyama	GAN GAN1 KLHL16	AHLVLDGEEIPVQKNILAAAsPYIRTKLNYNPPKDDGSTYK
Q9H2D6	S1955	Sugiyama	TRIOBP KIAA1662 TARA HRIHFB2122	KADGQRQALDyVELsPLtQAsPQRARTPARTPDRLAKQEEL
Q9H2U2	S317	Sugiyama	PPA2 HSPC124	DSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK___
Q9H488	S264	Sugiyama	POFUT1 FUT12 KIAA0180	DWKNACAMLKDGTAGSHFMAsPQCVGySRSTAAPLTMTMCL
Q9H6F5	S102	Sugiyama	CCDC86 CYCLON	QGQPEPGAAsPQRQQDLHLEsPQRQPEysPEsPRCQPKPSE
Q9H6F5	S113	Sugiyama	CCDC86 CYCLON	QRQQDLHLEsPQRQPEysPEsPRCQPKPSEEAPKCsQDQGV
Q9H6F5	S91	Sugiyama	CCDC86 CYCLON	RLQQGAGLEsPQGQPEPGAAsPQRQQDLHLEsPQRQPEysP
Q9H6F5	Y109	Sugiyama	CCDC86 CYCLON	AAsPQRQQDLHLEsPQRQPEysPEsPRCQPKPSEEAPKCsQ
Q9H7L9	S228	SIGNOR	SUDS3 SAP45 SDS3	NYLLTDEQIMEDLRTLNKLKsPKRPAsPssPEHLPAtPAEs
Q9NQR4	S207	Sugiyama	NIT2 CUA002	HWELLQRSRAVDNQVyVAtAsPARDDKASYVAWGHSTVVNP
Q9NQT8	T506	SIGNOR	KIF13B GAKIN KIAA0639	MGILPEHCIIDITSEGQVMLtPQKNTRTFVNGSsVSSPIQL
Q9NQX3	S270	Sugiyama	GPHN GPH KIAA1385	SRGVQVLPRDTAsLsttPsEsPRAQAtsRLstAsCPtPKVQ
Q9NR19	S267	PSP	ACSS2 ACAS2	CIVVKHLGRAELGMGDstsQsPPIKRSCPDVQISWNQGIDL
Q9NR30	S71	Sugiyama	DDX21	VFPKAKQVKKKAEPSEVDMNsPKSKKAKKKEEPSQNDIsPK
Q9NRA8	S115	Sugiyama	EIF4ENIF1	VRRIVDPRERVKEDDLDVVLsPQRRsFGGGCHVTAAVSSRR
Q9NUU7	S85	Sugiyama	DDX19A DDX19L	IRSNLVDNtNQVEVLQRDPNsPLysVKsFEELRLKPQLLQG
Q9NXR1	T191	EPSD\|PSP	NDE1 NUDE	DEARDLRQELAVQQKQEKPRtPMPSsVEAERTDTAVQAtGs
Q9NY27	S226	Sugiyama	PPP4R2 SBBI57	QNEEKNHSDsstsEsEVssVsPLKNKHPDEDAVEAEGHEVK
Q9NYB0	S203	Sugiyama	TERF2IP DRIP5 RAP1 PP8000	RYLKHLRGQEHKyLLGDAPVsPssQKLKRKAEEDPEAADsG
Q9NYF8	S290	Sugiyama	BCLAF1 BTF KIAA0164	ERsGsGsVGNGssRysPsQNsPIHHIPsRRsPAKtIAPQNA
Q9NYV4	S249	Sugiyama	CDK12 CRK7 CRKRS KIAA0904	DSSKQDDsPsGAsYGQDyDLsPsRsHtssNYDsYKKsPGsT
Q9NZ72	S68	SIGNOR\|EPSD\|PSP	STMN3 SCLIP	RAsGQsFEVILKsPSDLsPEsPMLssPPKKKDtsLEELQKR
Q9NZ72	S73	SIGNOR\|EPSD\|PSP	STMN3 SCLIP	sFEVILKsPSDLsPEsPMLssPPKKKDtsLEELQKRLEAAE
Q9NZB2	S990	Sugiyama	FAM120A C9orf10 KIAA0183 OSSA	FPLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKN
Q9NZB2	T991	Sugiyama	FAM120A C9orf10 KIAA0183 OSSA	PLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKNQ
Q9NZJ0	S425	Sugiyama	DTL CDT2 CDW1 DCAF2 L2DTL RAMP	TVGWAsQKKKESRPGLVTVtssQstPAKAPRAKCNPsNssP
Q9NZJ0	T429	Sugiyama	DTL CDT2 CDW1 DCAF2 L2DTL RAMP	AsQKKKESRPGLVTVtssQstPAKAPRAKCNPsNssPssAA
Q9NZT2	S378	Sugiyama	OGFR	LERsQGDEAGGHGEDRPEPLsPKEsKKRKLELSRREQPPTE
Q9P270	S48	Sugiyama	SLAIN2 KIAA1458	NEQLRSRsGAVQGAGsLGPGsPVRAGAsIPssGAAsPRGFP
Q9UBC2	S235	Sugiyama	EPS15L1 EPS15R	KKtVFPGAVPVLPAsPPPKDsLRstPsHGsVssLNstGsLs
Q9UBC2	S255	Sugiyama	EPS15L1 EPS15R	sLRstPsHGsVssLNstGsLsPKHsLKQTQPTVNWVVPVAD
Q9UD71	T75	GPS6\|SIGNOR\|EPSD	PPP1R1B DARPP32	QRASGEGHHLKsKRPNPCAYtPPSLKAVQRIAESHLQSIsN
Q9UEY8	S677	Sugiyama	ADD3 ADDL	NIEITIKsPEKIEEVLsPEGsPsKsPsKKKKKFRTPsFLKK
Q9UEY8	S681	Sugiyama	ADD3 ADDL	TIKsPEKIEEVLsPEGsPsKsPsKKKKKFRTPsFLKKNKKK
Q9UG63	S512	Sugiyama	ABCF2 HUSSY-18	EKEEMRKIIGRYGLTGKQQVsPIRNLSDGQKCRVCLAWLAW
Q9UI10	T86	Sugiyama	EIF2B4 EIF2BD	AAQCQVGPTRELPESGIQLGtPREKVPAGRSKAELRAERRA
Q9UI12	S367	Sugiyama	ATP6V1H CGI-11	QDLSSFDEySSELKSGRLEWsPVHKSEKFWRENAVRLNEKN
Q9UJU6	S232	Sugiyama	DBNL CMAP SH3P7 PP5423	RELREAARREQRyQEQGGEAsPQRtWEQQQEVVSRNRNEQE
Q9UKA9	S434	Sugiyama	PTBP2 NPTB PTB PTBLP	TVQLPREGLDDQGLTKDFGNsPLHRFKKPGSKNFQNIFPPS
Q9UKS6	S344	Sugiyama	PACSIN3	tLtsIVPTRDGTAPPPQsPGsPGtGQDEEWsDEEsPRKAAT
Q9UKS6	T347	Sugiyama	PACSIN3	sIVPTRDGTAPPPQsPGsPGtGQDEEWsDEEsPRKAATGVR
Q9UKV3	S256	Sugiyama	ACIN1 ACINUS KIAA0670	AAKLsEGsQPAEEEEDQEtPsRNLRVRADRNLKTEEEEEEE
Q9UKV3	T254	Sugiyama	ACIN1 ACINUS KIAA0670	ARAAKLsEGsQPAEEEEDQEtPsRNLRVRADRNLKTEEEEE
Q9UKV5	S516	SIGNOR\|EPSD\|PSP	AMFR RNF45	GRIQVPFPTQRsDsIRPALNsPVERPssDQEEGETSAQTER
Q9ULD2	S1255	Sugiyama	MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1	HNGDLCsPKRsPtssAIPLQsPRNsGsFPsPsIsPR_____
Q9ULW0	S486	SIGNOR\|PSP	TPX2 C20orf1 C20orf2 DIL2 HCA519	ILEDVVGVPEKKVLPITVPKsPAFALKNRIRMPtKEDEEED
Q9UM11	S163	EPSD\|PSP	FZR1 CDH1 FYR FZR KIAA1242	NDVsPYsLsPVSNKSQKLLRsPRKPTRKISKIPFKVLDAPE
Q9UM11	S40	EPSD\|PSP	FZR1 CDH1 FYR FZR KIAA1242	TMPRVTEMRRTLtPAssPVssPsKHGDRFIPSRAGANWSVN
Q9UM11	T121	EPSD\|PSP	FZR1 CDH1 FYR FZR KIAA1242	GAGIEKVQDPQTEDRRLQPstPEKKGLFTYSLsTKRssPDD
Q9UMR2	S86	Sugiyama	DDX19B DBP5 DDX19 TDBP	IRSNLVDNtNQVEVLQRDPNsPLysVKsFEELRLKPQLLQG
Q9UNX3	S32	Sugiyama	RPL26L1 RPL26P1	sKNRKRHFNAPSHVRRKIMssPLSKELRQKYNVRSMPIRKD
Q9UNX3	T8	Sugiyama	RPL26L1 RPL26P1	_____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UPQ0	S523	Sugiyama	LIMCH1 KIAA1102	VETTIARASVLDtsMsAGsGsPsKTVtPKAVPMLtPKPYsQ
Q9UPQ3	S521	Sugiyama	AGAP1 CENTG2 KIAA1099	SVCSSPSISSTTSPKLDPPPsPHANRKKHRRKKSTSNFKAD
Q9UQ35	S1657	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	RSGSSSKGRGPsPEGssstEssPEHPPKSRTARRGsRSsPE
Q9UQ35	T866	Sugiyama	SRRM2 KIAA0324 SRL300 SRM300 HSPC075	sGtPPRQGsItsPQANEQsVtPQRRsCFEssPDPELKsRtP
Q9UQL6	S279	EPSD\|PSP	HDAC5 KIAA0600	sEPNLKVRSRLKQKVAERRssPLLRRKDGTVIStFKKRAVE
Q9Y210	S14	EPSD\|PSP	TRPC6 TRP6	_______MsQsPAFGPRRGssPRGAAGAAARRNESQDyLLM
Q9Y266	S139	Sugiyama	NUDC	IDQKKDAENHEAQLKNGsLDsPGKQDtEEDEEEDEKDKGKL
Q9Y2V2	S41	Sugiyama	CARHSP1	LDtPRsRERsPsPLRGNVVPsPLPtRRtRtFsAtVRASQGP
Q9Y2X3	S514	Sugiyama	NOP58 NOL5 NOP5 HSPC120	KHIKEEPLsEEEPCtstAIAsPEKKKKKKKKRENED_____
Q9Y371	T145	GPS6\|EPSD	SH3GLB1 KIAA0491 CGI-61	QKRIGTADRELIQTSALNFLtPLRNFIEGDYKTIAKERKLL
Q9Y490	S425	SIGNOR\|EPSD\|PSP	TLN1 KIAA1027 TLN	sKDHFGLEGDEEstMLEDsVsPKKstVLQQQyNRVGKVEHG
Q9Y4P8	T415	Sugiyama	WIPI2 CGI-50	LVTQTYGAAAGKGTYVPssPtRLAYTDDLGAVGGACLEDEA
Q9Y5S2	S1693	Sugiyama	CDC42BPB KIAA1124	stKHstPsNssNPsGPPsPNsPHRsQLPLEGLEQPACDT__
Q9Y5U2	S146	Sugiyama	TSSC4	LAPsGRsPVEGLGRAHRsPAsPRVPPVPDYVAHPERWTKYS
Q9Y5Z4	S181	Sugiyama	HEBP2 C6orf34 SOUL	ILREDGKVFDEKVYYTAGYNsPVKLLNRNNEVWLIQKNEPT
Q9Y673	S62	Sugiyama	ALG5 HSPC149	EEKFFLNAKGQKETLPSIWDsPtKQLSVVVPSYNEEKRLPV
Q9Y6G9	S207	Sugiyama	DYNC1LI1 DNCLI1	EQKLIRDFQEyVEPGEDFPAsPQRRNtAsQEDKDDsVVLPL

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

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name	reactome_id	p	-log10p	ref_path	ref_path_lowest
Chromatin organization	R-HSA-4839726	8.614498e-11	10.065	0	0
Chromatin modifying enzymes	R-HSA-3247509	4.087117e-10	9.389	0	0
Cell Cycle, Mitotic	R-HSA-69278	1.274703e-09	8.895	0	0
Cell Cycle	R-HSA-1640170	2.458084e-09	8.609	0	0
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	R-HSA-2559584	1.154959e-06	5.937	0	0
Epigenetic regulation of gene expression	R-HSA-212165	2.209796e-06	5.656	1	0
Formation of WDR5-containing histone-modifying complexes	R-HSA-9772755	2.942922e-06	5.531	0	0
PKMTs methylate histone lysines	R-HSA-3214841	6.053342e-06	5.218	0	0
NRAGE signals death through JNK	R-HSA-193648	4.751280e-05	4.323	0	0
HATs acetylate histones	R-HSA-3214847	1.020318e-04	3.991	0	0
G1/S-Specific Transcription	R-HSA-69205	1.475170e-04	3.831	0	0
TP53 Regulates Transcription of Cell Cycle Genes	R-HSA-6791312	1.579254e-04	3.802	0	0
Transport of Mature mRNA derived from an Intron-Containing Transcript	R-HSA-159236	2.357643e-04	3.628	0	0
Formation of the embryonic stem cell BAF (esBAF) complex	R-HSA-9933946	3.919852e-04	3.407	0	0
RUNX3 regulates NOTCH signaling	R-HSA-8941856	4.724299e-04	3.326	0	0
Transport of Mature Transcript to Cytoplasm	R-HSA-72202	4.771478e-04	3.321	0	0
Mitotic Spindle Checkpoint	R-HSA-69618	5.418816e-04	3.266	0	0
Apoptotic execution phase	R-HSA-75153	7.065733e-04	3.151	0	0
Transcription of E2F targets under negative control by DREAM complex	R-HSA-1362277	8.889444e-04	3.051	0	0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	R-HSA-9934037	8.889444e-04	3.051	0	0
RNA Polymerase II Transcription Termination	R-HSA-73856	8.437934e-04	3.074	0	0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	R-HSA-141444	8.847473e-04	3.053	0	0
Amplification of signal from the kinetochores	R-HSA-141424	8.847473e-04	3.053	0	0
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	8.519426e-04	3.070	0	0
G0 and Early G1	R-HSA-1538133	1.058238e-03	2.975	0	0
Mitotic G1 phase and G1/S transition	R-HSA-453279	1.011919e-03	2.995	0	0
Cell Cycle Checkpoints	R-HSA-69620	1.035112e-03	2.985	0	0
Cell death signalling via NRAGE, NRIF and NADE	R-HSA-204998	1.216326e-03	2.915	0	0
ATP-dependent chromatin remodelers	R-HSA-9932444	1.559469e-03	2.807	0	0
SWI/SNF chromatin remodelers	R-HSA-9932451	1.559469e-03	2.807	0	0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	R-HSA-8939243	1.344434e-03	2.871	0	0
Deactivation of the beta-catenin transactivating complex	R-HSA-3769402	1.521137e-03	2.818	0	0
M Phase	R-HSA-68886	1.530678e-03	2.815	0	0
Mitotic Prometaphase	R-HSA-68877	1.381462e-03	2.860	0	0
Signaling by ALK fusions and activated point mutants	R-HSA-9725370	1.560163e-03	2.807	0	0
Signaling by ALK in cancer	R-HSA-9700206	1.560163e-03	2.807	0	0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	R-HSA-1362300	2.175115e-03	2.663	0	0
mRNA 3'-end processing	R-HSA-72187	2.210360e-03	2.656	0	0
Transcriptional regulation by RUNX1	R-HSA-8878171	2.138664e-03	2.670	0	0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	R-HSA-9931510	2.018824e-03	2.695	0	0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	R-HSA-6804116	2.175115e-03	2.663	0	0
S Phase	R-HSA-69242	2.215782e-03	2.654	0	0
Expression of BMAL (ARNTL), CLOCK, and NPAS2	R-HSA-9931509	2.309698e-03	2.636	0	0
DNA Damage/Telomere Stress Induced Senescence	R-HSA-2559586	2.273038e-03	2.643	0	0
G alpha (12/13) signalling events	R-HSA-416482	2.552719e-03	2.593	0	0
G1/S Transition	R-HSA-69206	2.680899e-03	2.572	0	0
Role of ABL in ROBO-SLIT signaling	R-HSA-428890	2.953113e-03	2.530	0	0
Cellular Senescence	R-HSA-2559583	3.358649e-03	2.474	0	0
Deadenylation of mRNA	R-HSA-429947	3.588732e-03	2.445	0	0
Regulation of TP53 Activity through Acetylation	R-HSA-6804758	3.642638e-03	2.439	0	0
Gene expression (Transcription)	R-HSA-74160	3.697781e-03	2.432	1	0
Cyclin A/B1/B2 associated events during G2/M transition	R-HSA-69273	3.642638e-03	2.439	0	0
p75 NTR receptor-mediated signalling	R-HSA-193704	3.674694e-03	2.435	0	0
Epigenetic regulation by WDR5-containing histone modifying complexes	R-HSA-9917777	3.932094e-03	2.405	1	0
Formation of the polybromo-BAF (pBAF) complex	R-HSA-9933939	4.031135e-03	2.395	0	0
NFE2L2 regulating anti-oxidant/detoxification enzymes	R-HSA-9818027	4.476700e-03	2.349	0	0
Activation of the pre-replicative complex	R-HSA-68962	5.084675e-03	2.294	0	0
RUNX1 regulates expression of components of tight junctions	R-HSA-8935964	5.469547e-03	2.262	0	0
Polo-like kinase mediated events	R-HSA-156711	5.345258e-03	2.272	0	0
Formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	5.790349e-03	2.237	0	0
Mitotic G2-G2/M phases	R-HSA-453274	6.488871e-03	2.188	0	0
Death Receptor Signaling	R-HSA-73887	6.566622e-03	2.183	0	0
EML4 and NUDC in mitotic spindle formation	R-HSA-9648025	6.753933e-03	2.170	0	0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	R-HSA-9820865	7.512409e-03	2.124	0	0
Diseases of mitotic cell cycle	R-HSA-9675126	7.623113e-03	2.118	0	0
Apoptotic cleavage of cellular proteins	R-HSA-111465	7.623113e-03	2.118	0	0
M-decay: degradation of maternal mRNAs by maternally stored factors	R-HSA-9820841	8.086656e-03	2.092	0	0
Regulation of NFE2L2 gene expression	R-HSA-9818749	8.819844e-03	2.055	0	0
Cardiogenesis	R-HSA-9733709	9.218585e-03	2.035	0	0
Regulation of endogenous retroelements	R-HSA-9842860	9.390317e-03	2.027	0	0
Mitotic Anaphase	R-HSA-68882	9.450354e-03	2.025	0	0
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	8.833355e-03	2.054	0	0
G2/M Transition	R-HSA-69275	8.783795e-03	2.056	0	0
Activation of ATR in response to replication stress	R-HSA-176187	9.218585e-03	2.035	0	0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	R-HSA-6804114	9.718471e-03	2.012	0	0
Mitotic Metaphase and Anaphase	R-HSA-2555396	1.012783e-02	1.994	0	0
Heme signaling	R-HSA-9707616	1.013216e-02	1.994	0	0
mRNA Splicing - Major Pathway	R-HSA-72163	1.020736e-02	1.991	0	0
Regulation of TP53 Activity	R-HSA-5633007	1.079043e-02	1.967	1	0
Aberrant regulation of mitotic cell cycle due to RB1 defects	R-HSA-9687139	1.290044e-02	1.889	0	0
Transcriptional Regulation by TP53	R-HSA-3700989	1.302771e-02	1.885	1	0
MITF-M-dependent gene expression	R-HSA-9856651	1.246595e-02	1.904	0	0
Nuclear import of Rev protein	R-HSA-180746	1.317787e-02	1.880	0	0
ISG15 antiviral mechanism	R-HSA-1169408	1.337006e-02	1.874	0	0
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	1.359618e-02	1.867	0	0
Separation of Sister Chromatids	R-HSA-2467813	1.469037e-02	1.833	0	0
mRNA Splicing	R-HSA-72172	1.444288e-02	1.840	0	0
Interactions of Rev with host cellular proteins	R-HSA-177243	1.547239e-02	1.810	0	0
Estrogen-dependent gene expression	R-HSA-9018519	1.549259e-02	1.810	0	0
RUNX1 regulates transcription of genes involved in BCR signaling	R-HSA-8939245	1.686897e-02	1.773	0	0
RUNX2 regulates chondrocyte maturation	R-HSA-8941284	1.686897e-02	1.773	0	0
Notch-HLH transcription pathway	R-HSA-350054	1.734703e-02	1.761	0	0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	R-HSA-6804115	1.734703e-02	1.761	0	0
Cell-extracellular matrix interactions	R-HSA-446353	1.769217e-02	1.752	0	0
RUNX2 regulates bone development	R-HSA-8941326	1.832007e-02	1.737	0	0
RNA Polymerase III Abortive And Retractive Initiation	R-HSA-749476	1.832007e-02	1.737	0	0
RNA Polymerase III Transcription	R-HSA-74158	1.832007e-02	1.737	0	0
RUNX3 regulates RUNX1-mediated transcription	R-HSA-8951911	1.855341e-02	1.732	0	0
Activation of HOX genes during differentiation	R-HSA-5619507	2.168739e-02	1.664	0	0
Activation of anterior HOX genes in hindbrain development during early embryogenesis	R-HSA-5617472	2.168739e-02	1.664	0	0
Aberrant regulation of mitotic exit in cancer due to RB1 defects	R-HSA-9687136	2.258695e-02	1.646	0	0
Transport of the SLBP Dependant Mature mRNA	R-HSA-159230	2.543516e-02	1.595	0	0
Regulation of FOXO transcriptional activity by acetylation	R-HSA-9617629	2.507268e-02	1.601	0	0
Rev-mediated nuclear export of HIV RNA	R-HSA-165054	2.483422e-02	1.605	0	0
CDC6 association with the ORC:origin complex	R-HSA-68689	2.588469e-02	1.587	0	0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	R-HSA-2660825	2.588469e-02	1.587	0	0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	R-HSA-2660826	2.588469e-02	1.587	0	0
Nuclear events stimulated by ALK signaling in cancer	R-HSA-9725371	2.628849e-02	1.580	0	0
Maternal to zygotic transition (MZT)	R-HSA-9816359	2.865627e-02	1.543	0	0
Signaling by NTRK1 (TRKA)	R-HSA-187037	2.870435e-02	1.542	1	0
Diseases of signal transduction by growth factor receptors and second messengers	R-HSA-5663202	2.733440e-02	1.563	0	0
Loss of MECP2 binding ability to 5hmC-DNA	R-HSA-9022534	3.166173e-02	1.499	0	0
Regulation of TP53 Activity through Association with Co-factors	R-HSA-6804759	3.224523e-02	1.492	0	0
Formation of the non-canonical BAF (ncBAF) complex	R-HSA-9933947	3.224523e-02	1.492	0	0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	R-HSA-5619107	3.027049e-02	1.519	0	0
Homology Directed Repair	R-HSA-5693538	3.090309e-02	1.510	0	0
Cyclin D associated events in G1	R-HSA-69231	3.139645e-02	1.503	0	0
G1 Phase	R-HSA-69236	3.139645e-02	1.503	0	0
HDR through MMEJ (alt-NHEJ)	R-HSA-5685939	3.224523e-02	1.492	0	0
Zygotic genome activation (ZGA)	R-HSA-9819196	2.994959e-02	1.524	0	0
MET interacts with TNS proteins	R-HSA-8875513	3.279296e-02	1.484	0	0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome	R-HSA-9944997	3.279296e-02	1.484	0	0
Loss of Function of KMT2D in Kabuki Syndrome	R-HSA-9944971	3.279296e-02	1.484	0	0
Regulation of MITF-M dependent genes involved in metabolism	R-HSA-9854907	3.279296e-02	1.484	0	0
Establishment of Sister Chromatid Cohesion	R-HSA-2468052	3.572471e-02	1.447	0	0
IP3 and IP4 transport between cytosol and nucleus	R-HSA-1855196	3.537141e-02	1.451	0	0
IP6 and IP7 transport between cytosol and nucleus	R-HSA-1855229	3.537141e-02	1.451	0	0
Nuclear Pore Complex (NPC) Disassembly	R-HSA-3301854	3.426258e-02	1.465	0	0
Signalling to ERKs	R-HSA-187687	3.426258e-02	1.465	0	0
Apoptosis induced DNA fragmentation	R-HSA-140342	3.572471e-02	1.447	0	0
Postmitotic nuclear pore complex (NPC) reformation	R-HSA-9615933	3.606187e-02	1.443	0	0
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	R-HSA-210746	3.731643e-02	1.428	0	0
DNA Double-Strand Break Repair	R-HSA-5693532	3.735444e-02	1.428	0	0
Transcriptional Regulation by VENTX	R-HSA-8853884	3.756898e-02	1.425	0	0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	R-HSA-8936459	3.846159e-02	1.415	0	0
Signaling by NTRKs	R-HSA-166520	4.029366e-02	1.395	1	0
Formation of the canonical BAF (cBAF) complex	R-HSA-9933937	4.063277e-02	1.391	0	0
Vpr-mediated nuclear import of PICs	R-HSA-180910	4.505560e-02	1.346	0	0
Circadian clock	R-HSA-9909396	4.133370e-02	1.384	1	0
Downregulation of TGF-beta receptor signaling	R-HSA-2173788	4.300148e-02	1.367	0	0
Activation of NOXA and translocation to mitochondria	R-HSA-111448	5.132076e-02	1.290	0	0
Regulation of HMOX1 expression and activity	R-HSA-9707587	5.132076e-02	1.290	0	0
RUNX2 regulates genes involved in differentiation of myeloid cells	R-HSA-8941333	5.132076e-02	1.290	0	0
RUNX3 regulates BCL2L11 (BIM) transcription	R-HSA-8952158	5.132076e-02	1.290	0	0
NFE2L2 regulating ER-stress associated genes	R-HSA-9818035	5.132076e-02	1.290	0	0
GRB7 events in ERBB2 signaling	R-HSA-1306955	5.132076e-02	1.290	0	0
MECP2 regulates transcription factors	R-HSA-9022707	5.122045e-02	1.291	0	0
Activation of PUMA and translocation to mitochondria	R-HSA-139915	5.122045e-02	1.291	0	0
RUNX3 regulates WNT signaling	R-HSA-8951430	5.122045e-02	1.291	0	0
Binding of TCF/LEF:CTNNB1 to target gene promoters	R-HSA-4411364	5.122045e-02	1.291	0	0
NOSTRIN mediated eNOS trafficking	R-HSA-203641	5.122045e-02	1.291	0	0
Cohesin Loading onto Chromatin	R-HSA-2470946	5.122045e-02	1.291	0	0
SHOC2 M1731 mutant abolishes MRAS complex function	R-HSA-9726840	5.122045e-02	1.291	0	0
RUNX2 regulates osteoblast differentiation	R-HSA-8940973	4.927969e-02	1.307	0	0
IPs transport between nucleus and cytosol	R-HSA-1855170	4.730287e-02	1.325	0	0
Transport of the SLBP independent Mature mRNA	R-HSA-159227	4.730287e-02	1.325	0	0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)	R-HSA-9845323	5.434707e-02	1.265	0	0
Transcriptional regulation by RUNX3	R-HSA-8878159	4.909276e-02	1.309	0	0
Mitotic Prophase	R-HSA-68875	5.587045e-02	1.253	0	0
Cyclin A:Cdk2-associated events at S phase entry	R-HSA-69656	5.635173e-02	1.249	0	0
DCC mediated attractive signaling	R-HSA-418885	5.028228e-02	1.299	0	0
RNA Polymerase I Transcription Initiation	R-HSA-73762	4.826626e-02	1.316	0	0
Deadenylation-dependent mRNA decay	R-HSA-429914	4.913138e-02	1.309	0	0
Signaling by NOTCH1 PEST Domain Mutants in Cancer	R-HSA-2644602	5.434707e-02	1.265	0	0
Constitutive Signaling by NOTCH1 PEST Domain Mutants	R-HSA-2644606	5.434707e-02	1.265	0	0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	R-HSA-2894862	5.434707e-02	1.265	0	0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	R-HSA-2894858	5.434707e-02	1.265	0	0
Signaling by NOTCH1 in Cancer	R-HSA-2644603	5.434707e-02	1.265	0	0
NGF-stimulated transcription	R-HSA-9031628	5.081183e-02	1.294	1	1
Regulation of Glucokinase by Glucokinase Regulatory Protein	R-HSA-170822	5.417650e-02	1.266	0	0
NS1 Mediated Effects on Host Pathways	R-HSA-168276	5.796953e-02	1.237	0	0
Mitotic Telophase/Cytokinesis	R-HSA-68884	5.881431e-02	1.231	0	0
Cellular response to heat stress	R-HSA-3371556	5.981242e-02	1.223	0	0
Prolonged ERK activation events	R-HSA-169893	6.122255e-02	1.213	0	0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	6.122255e-02	1.213	0	0
ARL13B-mediated ciliary trafficking of INPP5E	R-HSA-5624958	6.516592e-02	1.186	0	0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	R-HSA-8939246	6.757708e-02	1.170	0	0
Signaling by MRAS-complex mutants	R-HSA-9660537	6.757708e-02	1.170	0	0
Gain-of-function MRAS complexes activate RAF signaling	R-HSA-9726842	6.757708e-02	1.170	0	0
NOTCH4 Intracellular Domain Regulates Transcription	R-HSA-9013695	7.170209e-02	1.144	0	0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	R-HSA-9933387	6.534898e-02	1.185	0	0
Transport of Mature mRNAs Derived from Intronless Transcripts	R-HSA-159234	6.525937e-02	1.185	0	0
RNA Polymerase III Transcription Initiation	R-HSA-76046	6.534898e-02	1.185	0	0
Interleukin-15 signaling	R-HSA-8983432	7.292027e-02	1.137	0	0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex	R-HSA-9931530	7.292027e-02	1.137	1	1
Nuclear Envelope Breakdown	R-HSA-2980766	7.130274e-02	1.147	0	0
Interactions of Vpr with host cellular proteins	R-HSA-176033	6.525937e-02	1.185	0	0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence	R-HSA-9825895	6.757708e-02	1.170	0	0
Signaling by LTK	R-HSA-9842663	7.292027e-02	1.137	0	0
Interleukin-37 signaling	R-HSA-9008059	6.534898e-02	1.185	0	0
Resolution of Abasic Sites (AP sites)	R-HSA-73933	7.311882e-02	1.136	0	0
Disorders of Developmental Biology	R-HSA-9675151	7.346413e-02	1.134	0	0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex	R-HSA-9931521	7.346413e-02	1.134	0	0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	R-HSA-141405	7.346413e-02	1.134	0	0
Inactivation of APC/C via direct inhibition of the APC/C complex	R-HSA-141430	7.346413e-02	1.134	0	0
RUNX1 regulates transcription of genes involved in interleukin signaling	R-HSA-8939247	7.386712e-02	1.132	0	0
NFE2L2 regulating inflammation associated genes	R-HSA-9818026	7.386712e-02	1.132	0	0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	R-HSA-9673768	7.386712e-02	1.132	0	0
RET signaling	R-HSA-8853659	7.861320e-02	1.105	0	0
Signaling by NOTCH1	R-HSA-1980143	7.931820e-02	1.101	0	0
DNA Repair	R-HSA-73894	8.109853e-02	1.091	0	0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	R-HSA-9659787	8.870412e-02	1.052	0	0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	R-HSA-9661069	8.870412e-02	1.052	0	0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	R-HSA-176407	8.699971e-02	1.060	0	0
RNA Polymerase III Transcription Initiation From Type 2 Promoter	R-HSA-76066	8.346603e-02	1.078	0	0
FOXO-mediated transcription of cell cycle genes	R-HSA-9617828	8.346603e-02	1.078	0	0
TP53 Regulates Transcription of DNA Repair Genes	R-HSA-6796648	9.282054e-02	1.032	0	0
AKT phosphorylates targets in the nucleus	R-HSA-198693	8.630115e-02	1.064	0	0
Regulation of PD-L1(CD274) transcription	R-HSA-9909649	9.364373e-02	1.029	0	0
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	9.335892e-02	1.030	1	0
Caspase-mediated cleavage of cytoskeletal proteins	R-HSA-264870	8.630115e-02	1.064	0	0
Uptake and function of anthrax toxins	R-HSA-5210891	8.699971e-02	1.060	0	0
Signaling by Hippo	R-HSA-2028269	8.699971e-02	1.060	0	0
Regulation of MECP2 expression and activity	R-HSA-9022692	9.501984e-02	1.022	0	0
Nuclear RNA decay	R-HSA-9930044	9.501984e-02	1.022	0	0
RNA Polymerase III Transcription Initiation From Type 1 Promoter	R-HSA-76061	9.626876e-02	1.017	0	0
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	9.787011e-02	1.009	0	0
RUNX3 regulates CDKN1A transcription	R-HSA-8941855	1.000232e-01	1.000	0	0
Regulation of CDH19 Expression and Function	R-HSA-9764302	1.000232e-01	1.000	0	0
Negative feedback regulation of MAPK pathway	R-HSA-5674499	1.000232e-01	1.000	0	0
Loss of MECP2 binding ability to the NCoR/SMRT complex	R-HSA-9022537	1.000232e-01	1.000	0	0
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	1.009456e-01	0.996	0	0
Loss of Function of TP53 in Cancer	R-HSA-9723907	1.287312e-01	0.890	0	0
Defective translocation of RB1 mutants to the nucleus	R-HSA-9661070	1.287312e-01	0.890	0	0
Deletions in the AXIN1 gene destabilize the destruction complex	R-HSA-5467345	1.287312e-01	0.890	0	0
Loss of function of TP53 in cancer due to loss of tetramerization ability	R-HSA-9723905	1.287312e-01	0.890	0	0
APC truncation mutants are not K63 polyubiquitinated	R-HSA-5467333	1.287312e-01	0.890	0	0
Regulation of TP53 Expression	R-HSA-6804754	1.060916e-01	0.974	0	0
Defective Inhibition of DNA Recombination at Telomere	R-HSA-9670621	2.408971e-01	0.618	0	0
Alternative Lengthening of Telomeres (ALT)	R-HSA-9006821	2.408971e-01	0.618	0	0
Diseases of Telomere Maintenance	R-HSA-9673013	2.408971e-01	0.618	0	0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	R-HSA-9670613	2.408971e-01	0.618	0	0
Defective Mismatch Repair Associated With MLH1	R-HSA-5545483	2.408971e-01	0.618	0	0
Defective DNA double strand break response due to BRCA1 loss of function	R-HSA-9663199	2.408971e-01	0.618	0	0
Defective Mismatch Repair Associated With PMS2	R-HSA-5632987	2.408971e-01	0.618	0	0
Defective DNA double strand break response due to BARD1 loss of function	R-HSA-9699150	2.408971e-01	0.618	0	0
Impaired BRCA2 translocation to the nucleus	R-HSA-9709275	2.408971e-01	0.618	0	0
Defective Mismatch Repair Associated With MSH6	R-HSA-5632968	2.408971e-01	0.618	0	0
Impaired BRCA2 binding to SEM1 (DSS1)	R-HSA-9763198	2.408971e-01	0.618	0	0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations	R-HSA-9670615	2.408971e-01	0.618	0	0
Loss of MECP2 binding ability to 5mC-DNA	R-HSA-9022538	1.519744e-01	0.818	0	0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	R-HSA-8869496	1.292988e-01	0.888	0	0
RUNX1 regulates transcription of genes involved in WNT signaling	R-HSA-8939256	1.292988e-01	0.888	0	0
E2F-enabled inhibition of pre-replication complex formation	R-HSA-113507	1.292988e-01	0.888	0	0
MECP2 regulates transcription of genes involved in GABA signaling	R-HSA-9022927	2.008613e-01	0.697	0	0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	R-HSA-69200	2.008613e-01	0.697	0	0
Nef mediated downregulation of CD28 cell surface expression	R-HSA-164939	3.386286e-01	0.470	0	0
XAV939 stabilizes AXIN	R-HSA-5545619	3.386286e-01	0.470	0	0
Loss of Function of SMAD4 in Cancer	R-HSA-3304347	3.386286e-01	0.470	0	0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	R-HSA-5619101	3.386286e-01	0.470	0	0
Signaling by TCF7L2 mutants	R-HSA-5339700	3.386286e-01	0.470	0	0
Intestinal infectious diseases	R-HSA-8942233	3.386286e-01	0.470	0	0
Defective SLC9A9 causes autism 16 (AUTS16)	R-HSA-5619052	3.386286e-01	0.470	0	0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	R-HSA-5660686	3.386286e-01	0.470	0	0
SMAD2/3 MH2 Domain Mutants in Cancer	R-HSA-3315487	3.386286e-01	0.470	0	0
Defective VWF binding to collagen type I	R-HSA-9845622	3.386286e-01	0.470	0	0
SMAD4 MH2 Domain Mutants in Cancer	R-HSA-3311021	3.386286e-01	0.470	0	0
RUNX1 regulates estrogen receptor mediated transcription	R-HSA-8931987	1.611658e-01	0.793	0	0
SMAC (DIABLO) binds to IAPs	R-HSA-111463	2.512192e-01	0.600	0	0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	R-HSA-111464	2.512192e-01	0.600	0	0
Loss of phosphorylation of MECP2 at T308	R-HSA-9022535	2.512192e-01	0.600	0	0
Type I hemidesmosome assembly	R-HSA-446107	1.950890e-01	0.710	0	0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	R-HSA-77588	1.950890e-01	0.710	0	0
MET receptor recycling	R-HSA-8875656	1.950890e-01	0.710	0	0
Anchoring fibril formation	R-HSA-2214320	1.550846e-01	0.809	0	0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters	R-HSA-9931512	1.550846e-01	0.809	0	0
FOXO-mediated transcription of cell death genes	R-HSA-9614657	1.018049e-01	0.992	0	0
Signaling by cytosolic FGFR1 fusion mutants	R-HSA-1839117	1.018049e-01	0.992	0	0
RNA Polymerase III Transcription Termination	R-HSA-73980	1.018049e-01	0.992	0	0
E2F mediated regulation of DNA replication	R-HSA-113510	1.178396e-01	0.929	0	0
RUNX3 regulates p14-ARF	R-HSA-8951936	1.815157e-01	0.741	0	0
Repression of WNT target genes	R-HSA-4641265	1.815157e-01	0.741	0	0
SHC-related events triggered by IGF1R	R-HSA-2428933	1.815157e-01	0.741	0	0
Leading Strand Synthesis	R-HSA-69109	1.815157e-01	0.741	0	0
Polymerase switching	R-HSA-69091	1.815157e-01	0.741	0	0
GP1b-IX-V activation signalling	R-HSA-430116	2.305488e-01	0.637	0	0
NFE2L2 regulating MDR associated enzymes	R-HSA-9818032	2.305488e-01	0.637	0	0
ARMS-mediated activation	R-HSA-170984	2.305488e-01	0.637	0	0
ALK mutants bind TKIs	R-HSA-9700645	2.305488e-01	0.637	0	0
SMAC, XIAP-regulated apoptotic response	R-HSA-111469	3.018599e-01	0.520	0	0
Signalling to p38 via RIT and RIN	R-HSA-187706	3.018599e-01	0.520	0	0
Activation of caspases through apoptosome-mediated cleavage	R-HSA-111459	3.018599e-01	0.520	0	0
PTK6 Regulates Cell Cycle	R-HSA-8849470	3.018599e-01	0.520	0	0
Phosphorylation of Emi1	R-HSA-176417	3.018599e-01	0.520	0	0
Defective PAPSS2 causes SEMD-PA	R-HSA-3560796	4.237825e-01	0.373	0	0
Glycogen storage disease type IV (GBE1)	R-HSA-3878781	4.237825e-01	0.373	0	0
Defective OPLAH causes OPLAHD	R-HSA-5578998	4.237825e-01	0.373	0	0
Defective VWF cleavage by ADAMTS13 variant	R-HSA-9845621	4.237825e-01	0.373	0	0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1	R-HSA-5083633	4.237825e-01	0.373	0	0
Enhanced cleavage of VWF variant by ADAMTS13	R-HSA-9845619	4.237825e-01	0.373	0	0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2	R-HSA-5083629	4.237825e-01	0.373	0	0
Interleukin receptor SHC signaling	R-HSA-912526	1.100918e-01	0.958	0	0
Formation of definitive endoderm	R-HSA-9823730	1.350491e-01	0.870	0	0
APC-Cdc20 mediated degradation of Nek2A	R-HSA-179409	1.533661e-01	0.814	0	0
MET activates RAP1 and RAC1	R-HSA-8875555	2.670560e-01	0.573	0	0
DNA replication initiation	R-HSA-68952	2.670560e-01	0.573	0	0
Folding of actin by CCT/TriC	R-HSA-390450	2.670560e-01	0.573	0	0
Gap-filling DNA repair synthesis and ligation in GG-NER	R-HSA-5696397	1.727124e-01	0.763	0	0
Regulation of CDH1 mRNA translation by microRNAs	R-HSA-9764562	2.381821e-01	0.623	0	0
RUNX3 regulates YAP1-mediated transcription	R-HSA-8951671	3.518765e-01	0.454	0	0
G2/M DNA replication checkpoint	R-HSA-69478	3.518765e-01	0.454	0	0
Transport of Mature mRNA Derived from an Intronless Transcript	R-HSA-159231	1.089109e-01	0.963	0	0
RNA Polymerase III Transcription Initiation From Type 3 Promoter	R-HSA-76071	1.930007e-01	0.714	0	0
Activated NTRK3 signals through RAS	R-HSA-9034864	3.041615e-01	0.517	0	0
Erythropoietin activates RAS	R-HSA-9027284	2.679161e-01	0.572	0	0
Processive synthesis on the lagging strand	R-HSA-69183	2.679161e-01	0.572	0	0
APC/C:Cdc20 mediated degradation of Cyclin B	R-HSA-174048	2.386303e-01	0.622	0	0
MET promotes cell motility	R-HSA-8875878	1.739214e-01	0.760	0	0
Late endosomal microautophagy	R-HSA-9615710	2.122418e-01	0.673	0	0
Recognition of DNA damage by PCNA-containing replication complex	R-HSA-110314	2.360197e-01	0.627	0	0
Phosphorylation of the APC/C	R-HSA-176412	2.982580e-01	0.525	0	0
NFE2L2 regulates pentose phosphate pathway genes	R-HSA-9818028	3.414619e-01	0.467	0	0
Activated NTRK2 signals through RAS	R-HSA-9026519	3.414619e-01	0.467	0	0
Inhibition of replication initiation of damaged DNA by RB1/E2F1	R-HSA-113501	3.414619e-01	0.467	0	0
Signaling by AXIN mutants	R-HSA-4839735	3.414619e-01	0.467	0	0
Synthesis of PIPs in the nucleus	R-HSA-8847453	4.005907e-01	0.397	0	0
SOS-mediated signalling	R-HSA-112412	4.005907e-01	0.397	0	0
SLBP independent Processing of Histone Pre-mRNAs	R-HSA-111367	4.005907e-01	0.397	0	0
Defective GSS causes GSS deficiency	R-HSA-5579006	4.979768e-01	0.303	0	0
MET activates PTPN11	R-HSA-8865999	4.979768e-01	0.303	0	0
Invadopodia formation	R-HSA-8941237	4.979768e-01	0.303	0	0
SHC1 events in ERBB2 signaling	R-HSA-1250196	2.319407e-01	0.635	0	0
snRNP Assembly	R-HSA-191859	1.413515e-01	0.850	0	0
Metabolism of non-coding RNA	R-HSA-194441	1.413515e-01	0.850	0	0
Laminin interactions	R-HSA-3000157	2.585468e-01	0.587	0	0
Centrosome maturation	R-HSA-380287	1.172296e-01	0.931	0	0
Lagging Strand Synthesis	R-HSA-69186	2.902133e-01	0.537	0	0
MECP2 regulates neuronal receptors and channels	R-HSA-9022699	2.816122e-01	0.550	0	0
NOTCH2 intracellular domain regulates transcription	R-HSA-2197563	3.786021e-01	0.422	0	0
Disorders of Nervous System Development	R-HSA-9697154	3.786021e-01	0.422	0	0
Loss of function of MECP2 in Rett syndrome	R-HSA-9005891	3.786021e-01	0.422	0	0
Pervasive developmental disorders	R-HSA-9005895	3.786021e-01	0.422	0	0
Specification of primordial germ cells	R-HSA-9827857	3.598543e-01	0.444	0	0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	R-HSA-5358565	3.598543e-01	0.444	0	0
Removal of the Flap Intermediate from the C-strand	R-HSA-174437	3.598543e-01	0.444	0	0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	R-HSA-9828211	4.475090e-01	0.349	0	0
Regulation of NPAS4 mRNA translation	R-HSA-9768778	4.475090e-01	0.349	0	0
Nonhomologous End-Joining (NHEJ)	R-HSA-5693571	2.486535e-01	0.604	0	0
Regulation of HSF1-mediated heat shock response	R-HSA-3371453	1.582585e-01	0.801	0	0
Adenylate cyclase activating pathway	R-HSA-170660	4.152750e-01	0.382	0	0
Formation of axial mesoderm	R-HSA-9796292	4.152750e-01	0.382	0	0
Association of TriC/CCT with target proteins during biosynthesis	R-HSA-390471	3.157574e-01	0.501	0	0
Ephrin signaling	R-HSA-3928664	3.906911e-01	0.408	0	0
PCNA-Dependent Long Patch Base Excision Repair	R-HSA-5651801	3.906911e-01	0.408	0	0
PKA activation in glucagon signalling	R-HSA-164378	3.906911e-01	0.408	0	0
Transcriptional regulation by RUNX2	R-HSA-8878166	1.629820e-01	0.788	0	0
Switching of origins to a post-replicative state	R-HSA-69052	2.334672e-01	0.632	0	0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	R-HSA-9843970	3.375754e-01	0.472	0	0
Regulation of endogenous retroelements by KRAB-ZFP proteins	R-HSA-9843940	2.837908e-01	0.547	0	0
Translesion Synthesis by POLH	R-HSA-110320	4.213046e-01	0.375	0	0
Impaired BRCA2 binding to PALB2	R-HSA-9709603	4.213046e-01	0.375	0	0
Removal of the Flap Intermediate	R-HSA-69166	4.512205e-01	0.346	0	0
Inactivation of CDC42 and RAC1	R-HSA-428543	4.922864e-01	0.308	0	0
HCN channels	R-HSA-1296061	5.626216e-01	0.250	0	0
TNFR1-mediated ceramide production	R-HSA-5626978	5.626216e-01	0.250	0	0
AKT-mediated inactivation of FOXO1A	R-HSA-211163	5.626216e-01	0.250	0	0
TGFBR1 KD Mutants in Cancer	R-HSA-3656532	5.626216e-01	0.250	0	0
Signaling by MAP2K mutants	R-HSA-9652169	5.626216e-01	0.250	0	0
Defective LFNG causes SCDO3	R-HSA-5083630	5.626216e-01	0.250	0	0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	R-HSA-174178	3.346862e-01	0.475	0	0
PRC2 methylates histones and DNA	R-HSA-212300	3.817033e-01	0.418	0	0
AURKA Activation by TPX2	R-HSA-8854518	3.256483e-01	0.487	0	0
Defective homologous recombination repair (HRR) due to PALB2 loss of function	R-HSA-9701193	4.515312e-01	0.345	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	R-HSA-9704646	4.515312e-01	0.345	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	R-HSA-9704331	4.515312e-01	0.345	0	0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	R-HSA-9701192	4.515312e-01	0.345	0	0
Regulation of RUNX2 expression and activity	R-HSA-8939902	3.555572e-01	0.449	0	0
HDACs deacetylate histones	R-HSA-3214815	3.706159e-01	0.431	0	0
Adenylate cyclase inhibitory pathway	R-HSA-170670	4.862230e-01	0.313	0	0
Translesion synthesis by REV1	R-HSA-110312	4.862230e-01	0.313	0	0
RNA Polymerase III Chain Elongation	R-HSA-73780	4.862230e-01	0.313	0	0
ERBB2 Regulates Cell Motility	R-HSA-6785631	4.862230e-01	0.313	0	0
Processing of DNA double-strand break ends	R-HSA-5693607	3.464199e-01	0.460	0	0
Gap-filling DNA repair synthesis and ligation in TC-NER	R-HSA-6782210	3.887408e-01	0.410	0	0
Regulation of RUNX1 Expression and Activity	R-HSA-8934593	4.507366e-01	0.346	0	0
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	3.898765e-01	0.409	0	0
Loss of Nlp from mitotic centrosomes	R-HSA-380259	3.898765e-01	0.409	0	0
Recruitment of NuMA to mitotic centrosomes	R-HSA-380320	3.625601e-01	0.441	0	0
MECP2 regulates transcription of neuronal ligands	R-HSA-9022702	5.346964e-01	0.272	0	0
MAPK3 (ERK1) activation	R-HSA-110056	5.346964e-01	0.272	0	0
Activation of Ca-permeable Kainate Receptor	R-HSA-451308	5.346964e-01	0.272	0	0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	R-HSA-2151209	5.346964e-01	0.272	0	0
Processive synthesis on the C-strand of the telomere	R-HSA-174414	4.769775e-01	0.322	0	0
TNFR1-induced NF-kappa-B signaling pathway	R-HSA-5357956	4.769775e-01	0.322	0	0
Interaction between L1 and Ankyrins	R-HSA-445095	4.769775e-01	0.322	0	0
Translesion synthesis by POLI	R-HSA-5656121	5.201078e-01	0.284	0	0
GRB2:SOS provides linkage to MAPK signaling for Integrins	R-HSA-354194	5.201078e-01	0.284	0	0
Attenuation phase	R-HSA-3371568	4.699009e-01	0.328	0	0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	R-HSA-73779	4.699009e-01	0.328	0	0
Condensation of Prophase Chromosomes	R-HSA-2299718	4.668441e-01	0.331	0	0
mRNA Splicing - Minor Pathway	R-HSA-72165	4.668441e-01	0.331	0	0
activated TAK1 mediates p38 MAPK activation	R-HSA-450302	5.102660e-01	0.292	0	0
B-WICH complex positively regulates rRNA expression	R-HSA-5250924	4.640177e-01	0.333	0	0
Diseases of DNA Double-Strand Break Repair	R-HSA-9675136	4.967102e-01	0.304	0	0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function	R-HSA-9701190	4.967102e-01	0.304	0	0
Dual Incision in GG-NER	R-HSA-5696400	4.967102e-01	0.304	0	0
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	R-HSA-6781827	4.729389e-01	0.325	0	0
RNA Polymerase II HIV Promoter Escape	R-HSA-167162	5.129324e-01	0.290	0	0
HIV Transcription Initiation	R-HSA-167161	5.129324e-01	0.290	0	0
RNA Polymerase II Transcription Initiation	R-HSA-75953	5.129324e-01	0.290	0	0
Signaling by Erythropoietin	R-HSA-9006335	5.280848e-01	0.277	0	0
Impaired BRCA2 binding to RAD51	R-HSA-9709570	5.280848e-01	0.277	0	0
NOTCH3 Activation and Transmission of Signal to the Nucleus	R-HSA-9013507	5.385418e-01	0.269	0	0
SHC1 events in ERBB4 signaling	R-HSA-1250347	5.527381e-01	0.257	0	0
mRNA decay by 5' to 3' exoribonuclease	R-HSA-430039	5.527381e-01	0.257	0	0
Translesion synthesis by POLK	R-HSA-5655862	5.527381e-01	0.257	0	0
RUNX2 regulates genes involved in cell migration	R-HSA-8941332	5.746065e-01	0.241	0	0
Regulation of CDH11 mRNA translation by microRNAs	R-HSA-9759811	5.746065e-01	0.241	0	0
Signaling by APC mutants	R-HSA-4839744	5.746065e-01	0.241	0	0
Truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	5.746065e-01	0.241	0	0
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	5.746065e-01	0.241	0	0
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	5.746065e-01	0.241	0	0
NFE2L2 regulating TCA cycle genes	R-HSA-9818025	6.189454e-01	0.208	0	0
IRS activation	R-HSA-74713	6.189454e-01	0.208	0	0
G2 Phase	R-HSA-68911	6.189454e-01	0.208	0	0
NOSIP mediated eNOS trafficking	R-HSA-203754	6.189454e-01	0.208	0	0
Defective binding of VWF variant to GPIb:IX:V	R-HSA-9846298	6.189454e-01	0.208	0	0
SMAD2/3 Phosphorylation Motif Mutants in Cancer	R-HSA-3304356	6.189454e-01	0.208	0	0
Enhanced binding of GP1BA variant to VWF multimer:collagen	R-HSA-9845620	6.189454e-01	0.208	0	0
APC/C-mediated degradation of cell cycle proteins	R-HSA-174143	5.267247e-01	0.278	0	0
Regulation of mitotic cell cycle	R-HSA-453276	5.267247e-01	0.278	0	0
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	5.527944e-01	0.257	0	0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	R-HSA-167160	5.659650e-01	0.247	0	0
RNA Pol II CTD phosphorylation and interaction with CE	R-HSA-77075	5.659650e-01	0.247	0	0
RNA Polymerase II Promoter Escape	R-HSA-73776	5.546680e-01	0.256	0	0
PI3K events in ERBB2 signaling	R-HSA-1963642	5.840105e-01	0.234	0	0
p130Cas linkage to MAPK signaling for integrins	R-HSA-372708	5.840105e-01	0.234	0	0
HSF1-dependent transactivation	R-HSA-3371571	5.653488e-01	0.248	0	0
Orc1 removal from chromatin	R-HSA-68949	5.841034e-01	0.234	0	0
Condensation of Prometaphase Chromosomes	R-HSA-2514853	6.119571e-01	0.213	0	0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	R-HSA-9824878	6.119571e-01	0.213	0	0
Signaling by GSK3beta mutants	R-HSA-5339716	6.119571e-01	0.213	0	0
RNA Polymerase II Transcription Initiation And Promoter Clearance	R-HSA-76042	5.947584e-01	0.226	0	0
Deposition of new CENPA-containing nucleosomes at the centromere	R-HSA-606279	5.947584e-01	0.226	0	0
Nucleosome assembly	R-HSA-774815	5.947584e-01	0.226	0	0
CDK-mediated phosphorylation and removal of Cdc6	R-HSA-69017	6.204095e-01	0.207	0	0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	R-HSA-5693554	6.179787e-01	0.209	0	0
APC/C:Cdc20 mediated degradation of Securin	R-HSA-174154	6.329265e-01	0.199	0	0
APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176409	6.379115e-01	0.195	0	0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176814	6.549520e-01	0.184	0	0
MET activates PTK2 signaling	R-HSA-8874081	6.424689e-01	0.192	0	0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	R-HSA-9027276	6.467456e-01	0.189	0	0
Signaling by CTNNB1 phospho-site mutants	R-HSA-4839743	6.467456e-01	0.189	0	0
CTNNB1 S33 mutants aren't phosphorylated	R-HSA-5358747	6.467456e-01	0.189	0	0
CTNNB1 T41 mutants aren't phosphorylated	R-HSA-5358752	6.467456e-01	0.189	0	0
CTNNB1 S45 mutants aren't phosphorylated	R-HSA-5358751	6.467456e-01	0.189	0	0
CTNNB1 S37 mutants aren't phosphorylated	R-HSA-5358749	6.467456e-01	0.189	0	0
Defects of platelet adhesion to exposed collagen	R-HSA-9823587	6.680189e-01	0.175	0	0
CDH11 homotypic and heterotypic interactions	R-HSA-9833576	6.680189e-01	0.175	0	0
Loss of Function of SMAD2/3 in Cancer	R-HSA-3304349	6.680189e-01	0.175	0	0
PKB-mediated events	R-HSA-109703	6.680189e-01	0.175	0	0
PDE3B signalling	R-HSA-165160	6.680189e-01	0.175	0	0
Noncanonical activation of NOTCH3	R-HSA-9017802	6.680189e-01	0.175	0	0
Signaling by RNF43 mutants	R-HSA-5340588	6.680189e-01	0.175	0	0
Signaling by MAPK mutants	R-HSA-9652817	6.680189e-01	0.175	0	0
Dual incision in TC-NER	R-HSA-6782135	6.875844e-01	0.163	0	0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	R-HSA-72662	6.875844e-01	0.163	0	0
Packaging Of Telomere Ends	R-HSA-171306	6.659038e-01	0.177	0	0
Golgi Cisternae Pericentriolar Stack Reorganization	R-HSA-162658	6.790125e-01	0.168	0	0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	R-HSA-75035	6.790125e-01	0.168	0	0
HSF1 activation	R-HSA-3371511	7.051895e-01	0.152	0	0
SHC-mediated cascade:FGFR3	R-HSA-5654704	6.944262e-01	0.158	0	0
ERBB2 Activates PTK6 Signaling	R-HSA-8847993	7.088300e-01	0.149	0	0
Transcriptional Regulation by MECP2	R-HSA-8986944	1.568133e-01	0.805	0	0
DNA Damage Bypass	R-HSA-73893	1.013357e-01	0.994	0	0
DNA Replication Pre-Initiation	R-HSA-69002	3.152523e-01	0.501	0	0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	2.219449e-01	0.654	0	0
Regulation of TP53 Activity through Phosphorylation	R-HSA-6804756	1.704875e-01	0.768	1	1
Transcription of the HIV genome	R-HSA-167172	6.000748e-01	0.222	0	0
Assembly of the pre-replicative complex	R-HSA-68867	6.609855e-01	0.180	0	0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	R-HSA-9818564	1.191826e-01	0.924	1	0
Cyclin E associated events during G1/S transition	R-HSA-69202	1.277544e-01	0.894	0	0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	R-HSA-5693565	2.197508e-01	0.658	0	0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	R-HSA-9841922	1.191826e-01	0.924	1	1
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes	R-HSA-9851695	1.191826e-01	0.924	1	0
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	1.622378e-01	0.790	0	0
Signaling by NOTCH3	R-HSA-9012852	3.706159e-01	0.431	0	0
Aggrephagy	R-HSA-9646399	3.237144e-01	0.490	0	0
Synthesis of DNA	R-HSA-69239	2.158737e-01	0.666	0	0
Crosslinking of collagen fibrils	R-HSA-2243919	6.422146e-01	0.192	0	0
Integrin signaling	R-HSA-354192	2.942063e-01	0.531	0	0
NFE2L2 regulating tumorigenic genes	R-HSA-9818030	4.152750e-01	0.382	0	0
NOTCH3 Intracellular Domain Regulates Transcription	R-HSA-9013508	2.319407e-01	0.635	0	0
FOXO-mediated transcription	R-HSA-9614085	6.524230e-01	0.185	0	0
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	1.249064e-01	0.903	0	0
MET activates RAS signaling	R-HSA-8851805	3.786021e-01	0.422	0	0
RNA Polymerase I Promoter Clearance	R-HSA-73854	3.754524e-01	0.425	0	0
Telomere Extension By Telomerase	R-HSA-171319	5.027881e-01	0.299	0	0
VxPx cargo-targeting to cilium	R-HSA-5620916	6.690745e-01	0.175	0	0
Chromosome Maintenance	R-HSA-73886	5.872956e-01	0.231	0	0
Nucleotide Excision Repair	R-HSA-5696398	2.673300e-01	0.573	0	0
Termination of translesion DNA synthesis	R-HSA-5656169	3.529834e-01	0.452	0	0
p75NTR recruits signalling complexes	R-HSA-209543	6.467456e-01	0.189	0	0
PI5P Regulates TP53 Acetylation	R-HSA-6811555	2.092987e-01	0.679	0	0
mTORC1-mediated signalling	R-HSA-166208	1.930007e-01	0.714	0	0
Nuclear Envelope (NE) Reassembly	R-HSA-2995410	1.642925e-01	0.784	0	0
DNA Double Strand Break Response	R-HSA-5693606	2.408204e-01	0.618	0	0
DNA strand elongation	R-HSA-69190	4.254959e-01	0.371	0	0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	R-HSA-8862803	2.360197e-01	0.627	1	1
Neurodegenerative Diseases	R-HSA-8863678	2.360197e-01	0.627	1	0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	R-HSA-3371497	6.000748e-01	0.222	0	0
Signal attenuation	R-HSA-74749	2.670560e-01	0.573	0	0
Positive epigenetic regulation of rRNA expression	R-HSA-5250913	1.372682e-01	0.862	0	0
RNA Polymerase I Transcription	R-HSA-73864	4.069344e-01	0.390	0	0
Extension of Telomeres	R-HSA-180786	4.432750e-01	0.353	0	0
TP53 Regulates Transcription of Death Receptors and Ligands	R-HSA-6803211	7.088300e-01	0.149	0	0
Platelet Aggregation (Plug Formation)	R-HSA-76009	4.464740e-01	0.350	0	0
Frs2-mediated activation	R-HSA-170968	2.092987e-01	0.679	0	0
EPHB-mediated forward signaling	R-HSA-3928662	4.259880e-01	0.371	0	0
Assembly of collagen fibrils and other multimeric structures	R-HSA-2022090	4.432750e-01	0.353	0	0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	R-HSA-6803205	3.435008e-01	0.464	0	0
Regulation of TP53 Activity through Methylation	R-HSA-6804760	2.138557e-01	0.670	0	0
Formation of the posterior neural plate	R-HSA-9832991	3.041615e-01	0.517	0	0
Defective Intrinsic Pathway for Apoptosis	R-HSA-9734009	1.748776e-01	0.757	1	0
Telomere C-strand (Lagging Strand) Synthesis	R-HSA-174417	3.643650e-01	0.438	0	0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	R-HSA-2173796	4.038642e-01	0.394	0	0
G2/M DNA damage checkpoint	R-HSA-69473	3.442933e-01	0.463	0	0
HDR through Single Strand Annealing (SSA)	R-HSA-5685938	6.228179e-01	0.206	0	0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	R-HSA-5693567	1.588387e-01	0.799	0	0
MTOR signalling	R-HSA-165159	2.564651e-01	0.591	0	0
MAPK6/MAPK4 signaling	R-HSA-5687128	4.066146e-01	0.391	0	0
Mismatch Repair	R-HSA-5358508	3.906911e-01	0.408	0	0
IGF1R signaling cascade	R-HSA-2428924	4.071341e-01	0.390	0	0
Negative regulation of MAPK pathway	R-HSA-5675221	6.668994e-01	0.176	0	0
TRAF3-dependent IRF activation pathway	R-HSA-918233	3.289764e-01	0.483	0	0
RNA Polymerase II Transcription	R-HSA-73857	1.332903e-01	0.875	1	0
Signaling by WNT in cancer	R-HSA-4791275	4.254959e-01	0.371	0	0
Generic Transcription Pathway	R-HSA-212436	3.123254e-01	0.505	1	0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	R-HSA-2173793	2.725306e-01	0.565	0	0
POLB-Dependent Long Patch Base Excision Repair	R-HSA-110362	1.550846e-01	0.809	0	0
Formation of lateral plate mesoderm	R-HSA-9758920	3.018599e-01	0.520	0	0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	R-HSA-6803204	1.748776e-01	0.757	0	0
Processing of Intronless Pre-mRNAs	R-HSA-77595	3.289764e-01	0.483	0	0
Global Genome Nucleotide Excision Repair (GG-NER)	R-HSA-5696399	2.080521e-01	0.682	0	0
CRMPs in Sema3A signaling	R-HSA-399956	4.512205e-01	0.346	1	1
Regulation of CDH11 function	R-HSA-9762292	5.346964e-01	0.272	0	0
Transcriptional regulation by small RNAs	R-HSA-5578749	4.236091e-01	0.373	0	0
Regulation of localization of FOXO transcription factors	R-HSA-9614399	5.746065e-01	0.241	0	0
TP53 Regulates Transcription of Cell Death Genes	R-HSA-5633008	7.056465e-01	0.151	0	0
G2/M Checkpoints	R-HSA-69481	1.836099e-01	0.736	0	0
Interleukin-2 signaling	R-HSA-9020558	1.302523e-01	0.885	0	0
Activation of BH3-only proteins	R-HSA-114452	2.319407e-01	0.635	0	0
Adipogenesis	R-HSA-9843745	1.704349e-01	0.768	0	0
Downstream signaling of activated FGFR3	R-HSA-5654708	5.280848e-01	0.277	0	0
Downstream signaling of activated FGFR4	R-HSA-5654716	5.527944e-01	0.257	0	0
Downstream signaling of activated FGFR2	R-HSA-5654696	6.858451e-01	0.164	0	0
Cilium Assembly	R-HSA-5617833	2.388796e-01	0.622	0	0
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	4.971794e-01	0.303	0	0
Downregulation of SMAD2/3:SMAD4 transcriptional activity	R-HSA-2173795	6.002097e-01	0.222	0	0
DNA Replication	R-HSA-69306	4.104638e-01	0.387	0	0
Signaling by ERBB2 KD Mutants	R-HSA-9664565	5.280848e-01	0.277	0	0
Interleukin-2 family signaling	R-HSA-451927	3.237144e-01	0.490	0	0
TCF dependent signaling in response to WNT	R-HSA-201681	2.373009e-01	0.625	0	0
Cargo trafficking to the periciliary membrane	R-HSA-5620920	4.071209e-01	0.390	0	0
SARS-CoV-2 targets PDZ proteins in cell-cell junction	R-HSA-9705677	2.008613e-01	0.697	0	0
Dopamine receptors	R-HSA-390651	2.008613e-01	0.697	0	0
Telomere C-strand synthesis initiation	R-HSA-174430	1.250475e-01	0.903	0	0
Fibronectin matrix formation	R-HSA-1566977	1.671033e-01	0.777	0	0
TGFBR3 expression	R-HSA-9839394	1.406747e-01	0.852	0	0
Activation of RAC1	R-HSA-428540	3.414619e-01	0.467	0	0
Adrenoceptors	R-HSA-390696	4.475090e-01	0.349	0	0
Interleukin-6 signaling	R-HSA-1059683	4.152750e-01	0.382	0	0
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	2.080521e-01	0.682	0	0
PKA activation	R-HSA-163615	3.906911e-01	0.408	0	0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	R-HSA-427389	3.237144e-01	0.490	0	0
Gap junction degradation	R-HSA-190873	4.922864e-01	0.308	0	0
Regulation of gap junction activity	R-HSA-191650	5.626216e-01	0.250	0	0
TFAP2 (AP-2) family regulates transcription of cell cycle factors	R-HSA-8866911	5.626216e-01	0.250	0	0
PINK1-PRKN Mediated Mitophagy	R-HSA-5205685	5.027881e-01	0.299	0	0
Reelin signalling pathway	R-HSA-8866376	6.189454e-01	0.208	0	0
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	6.664827e-01	0.176	0	0
GLI proteins bind promoters of Hh responsive genes to promote transcription	R-HSA-5635851	6.680189e-01	0.175	0	0
RNA Polymerase I Transcription Termination	R-HSA-73863	6.659038e-01	0.177	0	0
Downstream signaling of activated FGFR1	R-HSA-5654687	6.858451e-01	0.164	0	0
Platelet Adhesion to exposed collagen	R-HSA-75892	6.790125e-01	0.168	0	0
Pre-NOTCH Expression and Processing	R-HSA-1912422	6.494291e-01	0.187	0	0
Organelle biogenesis and maintenance	R-HSA-1852241	2.423128e-01	0.616	0	0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	R-HSA-9860927	5.198036e-01	0.284	0	0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	R-HSA-110373	1.573499e-01	0.803	0	0
Neurexins and neuroligins	R-HSA-6794361	3.169636e-01	0.499	0	0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	4.244118e-01	0.372	0	0
TICAM1-dependent activation of IRF3/IRF7	R-HSA-9013973	6.119571e-01	0.213	0	0
p53-Dependent G1/S DNA damage checkpoint	R-HSA-69580	6.689653e-01	0.175	0	0
p53-Dependent G1 DNA Damage Response	R-HSA-69563	6.689653e-01	0.175	0	0
Oxidative Stress Induced Senescence	R-HSA-2559580	4.904431e-01	0.309	0	0
NOTCH1 Intracellular Domain Regulates Transcription	R-HSA-2122947	1.013357e-01	0.994	0	0
Signaling by ERBB2	R-HSA-1227986	3.385649e-01	0.470	0	0
Initiation of Nuclear Envelope (NE) Reformation	R-HSA-2995383	3.167178e-01	0.499	0	0
Activated NTRK2 signals through FRS2 and FRS3	R-HSA-9028731	6.467456e-01	0.189	0	0
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-5693616	6.858451e-01	0.164	0	0
HDR through Homologous Recombination (HRR)	R-HSA-5685942	4.588962e-01	0.338	0	0
RNA Polymerase II Pre-transcription Events	R-HSA-674695	4.565458e-01	0.341	0	0
EGR2 and SOX10-mediated initiation of Schwann cell myelination	R-HSA-9619665	1.917712e-01	0.717	0	0
Signaling by TGF-beta Receptor Complex	R-HSA-170834	1.716017e-01	0.765	0	0
Signalling to RAS	R-HSA-167044	4.812268e-01	0.318	0	0
Homologous DNA Pairing and Strand Exchange	R-HSA-5693579	5.863051e-01	0.232	0	0
Regulation of Expression and Function of Type II Classical Cadherins	R-HSA-9764260	1.750246e-01	0.757	0	0
Mitochondrial biogenesis	R-HSA-1592230	4.426276e-01	0.354	0	0
Resolution of D-Loop Structures	R-HSA-5693537	6.446434e-01	0.191	0	0
Signaling by MET	R-HSA-6806834	1.076997e-01	0.968	0	0
Signaling by FGFR1 in disease	R-HSA-5655302	2.389840e-01	0.622	0	0
Signaling by NOTCH2	R-HSA-1980145	4.967102e-01	0.304	0	0
Signaling by EGFR	R-HSA-177929	1.110383e-01	0.955	0	0
Late Phase of HIV Life Cycle	R-HSA-162599	1.235545e-01	0.908	0	0
Interleukin-6 family signaling	R-HSA-6783589	5.924631e-01	0.227	0	0
Pre-NOTCH Transcription and Translation	R-HSA-1912408	3.086942e-01	0.510	0	0
Diseases of Mismatch Repair (MMR)	R-HSA-5423599	1.519744e-01	0.818	0	0
Resolution of AP sites via the single-nucleotide replacement pathway	R-HSA-110381	2.512192e-01	0.600	0	0
Signaling by NOTCH1 HD Domain Mutants in Cancer	R-HSA-2691230	1.815157e-01	0.741	0	0
Constitutive Signaling by NOTCH1 HD Domain Mutants	R-HSA-2691232	1.815157e-01	0.741	0	0
TNFR1-induced proapoptotic signaling	R-HSA-5357786	1.533661e-01	0.814	0	0
Polymerase switching on the C-strand of the telomere	R-HSA-174411	1.406747e-01	0.852	0	0
CLEC7A (Dectin-1) induces NFAT activation	R-HSA-5607763	4.512205e-01	0.346	0	0
Calcineurin activates NFAT	R-HSA-2025928	4.922864e-01	0.308	0	0
Activated NOTCH1 Transmits Signal to the Nucleus	R-HSA-2122948	4.507366e-01	0.346	0	0
Josephin domain DUBs	R-HSA-5689877	5.346964e-01	0.272	0	0
RAF activation	R-HSA-5673000	4.967102e-01	0.304	0	0
PTK6 Down-Regulation	R-HSA-8849472	6.189454e-01	0.208	0	0
Post-transcriptional silencing by small RNAs	R-HSA-426496	6.189454e-01	0.208	0	0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	R-HSA-5358606	5.840105e-01	0.234	0	0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis	R-HSA-9623433	6.119571e-01	0.213	0	0
Resolution of D-loop Structures through Holliday Junction Intermediates	R-HSA-5693568	6.228179e-01	0.206	0	0
RAB GEFs exchange GTP for GDP on RABs	R-HSA-8876198	6.426573e-01	0.192	0	0
SLC15A4:TASL-dependent IRF5 activation	R-HSA-9860276	6.680189e-01	0.175	0	0
Signaling by NODAL	R-HSA-1181150	6.690745e-01	0.175	0	0
Defective pyroptosis	R-HSA-9710421	7.032383e-01	0.153	0	0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	R-HSA-450321	6.944262e-01	0.158	0	0
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	1.747498e-01	0.758	0	0
TNF signaling	R-HSA-75893	2.725306e-01	0.565	0	0
Mitophagy	R-HSA-5205647	4.967102e-01	0.304	0	0
ESR-mediated signaling	R-HSA-8939211	2.399606e-01	0.620	0	0
Kinesins	R-HSA-983189	1.523638e-01	0.817	0	0
Ovarian tumor domain proteases	R-HSA-5689896	2.645903e-01	0.577	0	0
Regulation of CDH11 Expression and Function	R-HSA-9759475	3.529834e-01	0.452	0	0
UCH proteinases	R-HSA-5689603	6.071856e-01	0.217	0	0
Oncogene Induced Senescence	R-HSA-2559585	3.595826e-01	0.444	0	0
Clathrin-mediated endocytosis	R-HSA-8856828	7.086124e-01	0.150	0	0
Signaling by TGFB family members	R-HSA-9006936	4.094285e-01	0.388	0	0
Signaling by ERBB2 TMD/JMD mutants	R-HSA-9665686	5.924631e-01	0.227	0	0
Signaling by FLT3 fusion proteins	R-HSA-9703465	4.507366e-01	0.346	0	0
Macroautophagy	R-HSA-1632852	5.093113e-01	0.293	0	0
Transcriptional activation of cell cycle inhibitor p21	R-HSA-69895	2.008613e-01	0.697	0	0
Transcriptional activation of p53 responsive genes	R-HSA-69560	2.008613e-01	0.697	0	0
Release of Hh-Np from the secreting cell	R-HSA-5362798	3.018599e-01	0.520	0	0
Formation of intermediate mesoderm	R-HSA-9761174	2.670560e-01	0.573	0	0
Dopamine Neurotransmitter Release Cycle	R-HSA-212676	3.435008e-01	0.464	0	0
DNA Damage Recognition in GG-NER	R-HSA-5696394	3.157574e-01	0.501	0	0
BBSome-mediated cargo-targeting to cilium	R-HSA-5620922	4.515312e-01	0.345	0	0
GPER1 signaling	R-HSA-9634597	5.070437e-01	0.295	0	0
Signaling by ERBB2 ECD mutants	R-HSA-9665348	6.138518e-01	0.212	0	0
Signaling by NOTCH4	R-HSA-9013694	6.917046e-01	0.160	0	0
Diseases of programmed cell death	R-HSA-9645723	5.770181e-01	0.239	1	0
Autophagy	R-HSA-9612973	4.441435e-01	0.352	0	0
Regulation of TNFR1 signaling	R-HSA-5357905	2.166095e-01	0.664	0	0
Deubiquitination	R-HSA-5688426	1.402745e-01	0.853	0	0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	R-HSA-9634638	5.659650e-01	0.247	0	0
Intra-Golgi and retrograde Golgi-to-ER traffic	R-HSA-6811442	6.103959e-01	0.214	0	0
Protein-protein interactions at synapses	R-HSA-6794362	3.058235e-01	0.515	0	0
Ub-specific processing proteases	R-HSA-5689880	5.620894e-01	0.250	0	0
PTK6 Regulates Proteins Involved in RNA Processing	R-HSA-8849468	2.512192e-01	0.600	0	0
Transcriptional regulation of brown and beige adipocyte differentiation	R-HSA-9843743	3.237144e-01	0.490	0	0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	R-HSA-9844594	3.237144e-01	0.490	0	0
Rap1 signalling	R-HSA-392517	4.213046e-01	0.375	0	0
Synthesis of PIPs at the late endosome membrane	R-HSA-1660517	5.840105e-01	0.234	0	0
Regulation of gene expression by Hypoxia-inducible Factor	R-HSA-1234158	6.119571e-01	0.213	0	0
Myogenesis	R-HSA-525793	6.424689e-01	0.192	0	0
Mitochondrial unfolded protein response (UPRmt)	R-HSA-9841251	6.659038e-01	0.177	0	0
IL-6-type cytokine receptor ligand interactions	R-HSA-6788467	6.790125e-01	0.168	0	0
Signaling by FGFR4	R-HSA-5654743	7.032383e-01	0.153	0	0
FGFR1 mutant receptor activation	R-HSA-1839124	4.494862e-01	0.347	0	0
Transcriptional regulation of granulopoiesis	R-HSA-9616222	1.756853e-01	0.755	0	0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	R-HSA-5649702	4.922864e-01	0.308	0	0
Sensing of DNA Double Strand Breaks	R-HSA-5693548	6.119571e-01	0.213	0	0
Response of EIF2AK1 (HRI) to heme deficiency	R-HSA-9648895	5.659650e-01	0.247	0	0
Signaling by ERBB2 in Cancer	R-HSA-1227990	3.771562e-01	0.423	0	0
HIV Life Cycle	R-HSA-162587	1.361639e-01	0.866	0	0
TGF-beta receptor signaling activates SMADs	R-HSA-2173789	2.743410e-01	0.562	0	0
EGFR downregulation	R-HSA-182971	4.013574e-01	0.396	0	0
COPI-dependent Golgi-to-ER retrograde traffic	R-HSA-6811434	5.082409e-01	0.294	0	0
Regulation of Homotypic Cell-Cell Adhesion	R-HSA-9759476	5.712120e-01	0.243	0	0
Cell junction organization	R-HSA-446728	4.626406e-01	0.335	0	0
Rab regulation of trafficking	R-HSA-9007101	6.302572e-01	0.200	0	0
Selective autophagy	R-HSA-9663891	4.673164e-01	0.330	0	0
Apoptotic factor-mediated response	R-HSA-111471	6.138518e-01	0.212	0	0
HDMs demethylate histones	R-HSA-3214842	1.406747e-01	0.852	0	0
Collagen degradation	R-HSA-1442490	3.555572e-01	0.449	0	0
Metabolism of RNA	R-HSA-8953854	2.355525e-01	0.628	0	0
Adherens junctions interactions	R-HSA-418990	6.479788e-01	0.188	0	0
Intrinsic Pathway for Apoptosis	R-HSA-109606	3.887408e-01	0.410	0	0
Signaling by Receptor Tyrosine Kinases	R-HSA-9006934	5.743578e-01	0.241	1	0
Signal Transduction	R-HSA-162582	6.183793e-01	0.209	1	0
Formation of editosomes by ADAR proteins	R-HSA-77042	2.408971e-01	0.618	0	0
Defective Mismatch Repair Associated With MSH2	R-HSA-5632928	3.386286e-01	0.470	0	0
Positive Regulation of CDH1 Gene Transcription	R-HSA-9764790	1.072535e-01	0.970	0	0
mRNA Editing: A to I Conversion	R-HSA-75064	4.237825e-01	0.373	0	0
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis	R-HSA-9708296	4.237825e-01	0.373	0	0
C6 deamination of adenosine	R-HSA-75102	4.237825e-01	0.373	0	0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	R-HSA-446343	4.237825e-01	0.373	0	0
TGFBR3 regulates activin signaling	R-HSA-9839406	4.237825e-01	0.373	0	0
Regulation of PTEN localization	R-HSA-8948747	4.005907e-01	0.397	0	0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	R-HSA-5368598	4.979768e-01	0.303	0	0
NEP/NS2 Interacts with the Cellular Export Machinery	R-HSA-168333	2.012481e-01	0.696	0	0
Constitutive Signaling by Overexpressed ERBB2	R-HSA-9634285	3.786021e-01	0.422	0	0
Sodium/Proton exchangers	R-HSA-425986	4.475090e-01	0.349	0	0
Formation of annular gap junctions	R-HSA-196025	4.475090e-01	0.349	0	0
Membrane binding and targetting of GAG proteins	R-HSA-174490	4.152750e-01	0.382	0	0
Synaptic adhesion-like molecules	R-HSA-8849932	3.906911e-01	0.408	0	0
Serotonin Neurotransmitter Release Cycle	R-HSA-181429	3.906911e-01	0.408	0	0
Alanine metabolism	R-HSA-8964540	5.626216e-01	0.250	0	0
Budding and maturation of HIV virion	R-HSA-162588	4.013574e-01	0.396	0	0
Negative regulation of MET activity	R-HSA-6807004	4.515312e-01	0.345	0	0
Differentiation of T cells	R-HSA-9945266	5.201078e-01	0.284	0	0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)	R-HSA-9942503	5.201078e-01	0.284	0	0
Golgi-to-ER retrograde transport	R-HSA-8856688	3.897200e-01	0.409	0	0
Ionotropic activity of kainate receptors	R-HSA-451306	5.746065e-01	0.241	0	0
Trafficking of myristoylated proteins to the cilium	R-HSA-5624138	6.189454e-01	0.208	0	0
Loss of Function of TGFBR1 in Cancer	R-HSA-3656534	6.189454e-01	0.208	0	0
HIV Infection	R-HSA-162906	5.258600e-01	0.279	0	0
Signaling by EGFRvIII in Cancer	R-HSA-5637812	5.840105e-01	0.234	0	0
Constitutive Signaling by EGFRvIII	R-HSA-5637810	5.840105e-01	0.234	0	0
Signaling by AMER1 mutants	R-HSA-4839748	6.119571e-01	0.213	0	0
Synthesis of PS	R-HSA-1483101	6.680189e-01	0.175	0	0
Sensory perception of salty taste	R-HSA-9730628	6.680189e-01	0.175	0	0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	R-HSA-5676594	6.790125e-01	0.168	0	0
Cell-Cell communication	R-HSA-1500931	5.380165e-01	0.269	0	0
Regulation of Expression and Function of Type I Classical Cadherins	R-HSA-9764274	6.388209e-01	0.195	0	0
Regulation of CDH1 Expression and Function	R-HSA-9764265	6.388209e-01	0.195	0	0
Regulation of CDH1 Gene Transcription	R-HSA-9764560	1.277544e-01	0.894	0	0
Nervous system development	R-HSA-9675108	4.309162e-01	0.366	1	0
Gastrulation	R-HSA-9758941	6.124545e-01	0.213	0	0
Negative Regulation of CDH1 Gene Transcription	R-HSA-9764725	2.339747e-01	0.631	0	0
Chaperone Mediated Autophagy	R-HSA-9613829	6.138518e-01	0.212	0	0
Interleukin-4 and Interleukin-13 signaling	R-HSA-6785807	2.555164e-01	0.593	0	0
Regulation of PTEN gene transcription	R-HSA-8943724	1.523638e-01	0.817	0	0
Signaling by FGFR4 in disease	R-HSA-5655291	4.512205e-01	0.346	0	0
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	1.754066e-01	0.756	1	1
Regulation of beta-cell development	R-HSA-186712	2.197508e-01	0.658	0	0
Signaling by ERBB4	R-HSA-1236394	5.757396e-01	0.240	0	0
NOTCH2 Activation and Transmission of Signal to the Nucleus	R-HSA-2979096	6.944262e-01	0.158	0	0
Axon guidance	R-HSA-422475	5.615588e-01	0.251	1	0
Synthesis of PIPs at the Golgi membrane	R-HSA-1660514	4.507366e-01	0.346	0	0
Cytoprotection by HMOX1	R-HSA-9707564	7.074033e-01	0.150	0	0
MAP kinase activation	R-HSA-450294	4.793852e-01	0.319	0	0
Regulation of CDH11 gene transcription	R-HSA-9762293	4.922864e-01	0.308	0	0
PKA-mediated phosphorylation of CREB	R-HSA-111931	4.812268e-01	0.318	0	0
Receptor Mediated Mitophagy	R-HSA-8934903	5.346964e-01	0.272	0	0
Interleukin-17 signaling	R-HSA-448424	5.099818e-01	0.292	0	0
Long-term potentiation	R-HSA-9620244	6.179787e-01	0.209	0	0
Signaling by CSF1 (M-CSF) in myeloid cells	R-HSA-9680350	6.656589e-01	0.177	0	0
Sema4D induced cell migration and growth-cone collapse	R-HSA-416572	6.690745e-01	0.175	0	0
ERK/MAPK targets	R-HSA-198753	6.944262e-01	0.158	0	0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	R-HSA-9029569	6.875844e-01	0.163	0	0
Interleukin-7 signaling	R-HSA-1266695	6.179787e-01	0.209	0	0
FLT3 signaling in disease	R-HSA-9682385	7.051895e-01	0.152	0	0
FLT3 Signaling	R-HSA-9607240	4.915540e-01	0.308	0	0
Cytochrome c-mediated apoptotic response	R-HSA-111461	3.414619e-01	0.467	0	0
Inhibition of nitric oxide production	R-HSA-9636249	1.519744e-01	0.818	0	0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	R-HSA-111453	1.950890e-01	0.710	0	0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	R-HSA-446388	3.018599e-01	0.520	0	0
SARS-CoV-2 modulates autophagy	R-HSA-9754560	3.041615e-01	0.517	0	0
Uptake and function of diphtheria toxin	R-HSA-5336415	4.005907e-01	0.397	0	0
Synthesis And Processing Of GAG, GAGPOL Polyproteins	R-HSA-174495	4.512205e-01	0.346	0	0
NOTCH4 Activation and Transmission of Signal to the Nucleus	R-HSA-9013700	4.922864e-01	0.308	0	0
Signaling by Ligand-Responsive EGFR Variants in Cancer	R-HSA-5637815	6.944262e-01	0.158	0	0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	R-HSA-1236382	6.944262e-01	0.158	0	0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	R-HSA-8864260	1.863732e-01	0.730	0	0
Synthesis of PIPs at the early endosome membrane	R-HSA-1660516	4.241592e-01	0.372	0	0
Nuclear signaling by ERBB4	R-HSA-1251985	3.237144e-01	0.490	0	0
Diseases of DNA repair	R-HSA-9675135	4.668441e-01	0.331	0	0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	R-HSA-8866652	4.769775e-01	0.322	0	0
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	5.280848e-01	0.277	0	0
Signaling by NTRK2 (TRKB)	R-HSA-9006115	3.051099e-01	0.516	1	0
Base Excision Repair	R-HSA-73884	3.915862e-01	0.407	0	0
STAT3 nuclear events downstream of ALK signaling	R-HSA-9701898	2.679161e-01	0.572	0	0
Formation of the dystrophin-glycoprotein complex (DGC)	R-HSA-9913351	4.013574e-01	0.396	0	0
Apoptosis	R-HSA-109581	2.851918e-01	0.545	0	0
Formation of the ureteric bud	R-HSA-9830674	5.659650e-01	0.247	0	0
TBC/RABGAPs	R-HSA-8854214	7.032383e-01	0.153	0	0
Netrin-1 signaling	R-HSA-373752	4.259880e-01	0.371	0	0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	R-HSA-9825892	3.167178e-01	0.499	0	0
Regulation of MITF-M-dependent genes involved in pigmentation	R-HSA-9824585	1.210930e-01	0.917	0	0
Signaling by TGFBR3	R-HSA-9839373	3.298489e-01	0.482	0	0
Breakdown of the nuclear lamina	R-HSA-352238	3.386286e-01	0.470	0	0
Regulation of MITF-M dependent genes involved in invasion	R-HSA-9854909	2.512192e-01	0.600	0	0
Regulation of MITF-M-dependent genes involved in apoptosis	R-HSA-9824594	1.533661e-01	0.814	0	0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	R-HSA-8866910	3.289764e-01	0.483	0	0
SLC-mediated bile acid transport	R-HSA-9958517	4.475090e-01	0.349	0	0
Retrograde neurotrophin signalling	R-HSA-177504	4.512205e-01	0.346	0	0
Sensory perception of sour taste	R-HSA-9729555	5.626216e-01	0.250	0	0
Regulation of the apoptosome activity	R-HSA-9627069	5.346964e-01	0.272	0	0
Viral Messenger RNA Synthesis	R-HSA-168325	4.793852e-01	0.319	0	0
Utilization of Ketone Bodies	R-HSA-77108	5.746065e-01	0.241	0	0
RHOBTB3 ATPase cycle	R-HSA-9706019	5.746065e-01	0.241	0	0
Depolymerization of the Nuclear Lamina	R-HSA-4419969	6.138518e-01	0.212	0	0
RMTs methylate histone arginines	R-HSA-3214858	1.863732e-01	0.730	0	0
PI Metabolism	R-HSA-1483255	6.900232e-01	0.161	0	0
SARS-CoV-2-host interactions	R-HSA-9705683	6.696127e-01	0.174	0	0
Programmed Cell Death	R-HSA-5357801	5.247577e-01	0.280	0	0
Non-integrin membrane-ECM interactions	R-HSA-3000171	5.915990e-01	0.228	0	0
Apoptotic cleavage of cell adhesion proteins	R-HSA-351906	1.950890e-01	0.710	0	0
MITF-M-regulated melanocyte development	R-HSA-9730414	1.292408e-01	0.889	0	0
Formation of apoptosome	R-HSA-111458	5.346964e-01	0.272	0	0
Basigin interactions	R-HSA-210991	6.944262e-01	0.158	0	0
SARS-CoV-2 activates/modulates innate and adaptive immune responses	R-HSA-9705671	6.177948e-01	0.209	0	0
Sensory processing of sound by inner hair cells of the cochlea	R-HSA-9662360	2.548646e-01	0.594	0	0
tRNA processing in the nucleus	R-HSA-6784531	3.726727e-01	0.429	0	0
Suppression of apoptosis	R-HSA-9635465	5.746065e-01	0.241	0	0
Tie2 Signaling	R-HSA-210993	6.138518e-01	0.212	0	0
Constitutive Signaling by AKT1 E17K in Cancer	R-HSA-5674400	2.141365e-01	0.669	0	0
MHC class II antigen presentation	R-HSA-2132295	3.419429e-01	0.466	0	0
Formation of the anterior neural plate	R-HSA-9823739	4.862230e-01	0.313	0	0
Signaling by PTK6	R-HSA-8848021	5.149711e-01	0.288	0	0
Signaling by Non-Receptor Tyrosine Kinases	R-HSA-9006927	5.149711e-01	0.288	0	0
Interleukin-3, Interleukin-5 and GM-CSF signaling	R-HSA-512988	2.564651e-01	0.591	0	0
Signaling by ALK	R-HSA-201556	1.089109e-01	0.963	0	0
NrCAM interactions	R-HSA-447038	2.512192e-01	0.600	0	0
Transport of Ribonucleoproteins into the Host Nucleus	R-HSA-168271	1.323300e-01	0.878	0	0
Displacement of DNA glycosylase by APEX1	R-HSA-110357	4.005907e-01	0.397	0	0
Activation of the TFAP2 (AP-2) family of transcription factors	R-HSA-8866907	4.922864e-01	0.308	0	0
Collagen chain trimerization	R-HSA-8948216	4.038642e-01	0.394	0	0
Signaling by PDGFR in disease	R-HSA-9671555	5.102660e-01	0.292	0	0
Downregulation of ERBB2:ERBB3 signaling	R-HSA-1358803	6.467456e-01	0.189	0	0
Cleavage of the damaged pyrimidine	R-HSA-110329	6.854126e-01	0.164	0	0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	R-HSA-9029558	6.790125e-01	0.168	0	0
Regulation of KIT signaling	R-HSA-1433559	7.088300e-01	0.149	0	0
Depyrimidination	R-HSA-73928	6.854126e-01	0.164	0	0
L1CAM interactions	R-HSA-373760	7.074874e-01	0.150	0	0
Antiviral mechanism by IFN-stimulated genes	R-HSA-1169410	2.741391e-01	0.562	0	0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	R-HSA-110328	4.967102e-01	0.304	0	0
Sensory processing of sound	R-HSA-9659379	3.169756e-01	0.499	0	0
AKT phosphorylates targets in the cytosol	R-HSA-198323	6.467456e-01	0.189	0	0
NOD1/2 Signaling Pathway	R-HSA-168638	6.656589e-01	0.177	0	0
Calmodulin induced events	R-HSA-111933	7.051895e-01	0.152	0	0
Regulation of cholesterol biosynthesis by SREBP (SREBF)	R-HSA-1655829	3.169756e-01	0.499	0	0
CaM pathway	R-HSA-111997	7.051895e-01	0.152	0	0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	R-HSA-3134973	2.512192e-01	0.600	0	0
Export of Viral Ribonucleoproteins from Nucleus	R-HSA-168274	2.166095e-01	0.664	0	0
Epithelial-Mesenchymal Transition (EMT) during gastrulation	R-HSA-9758919	6.680189e-01	0.175	0	0
Signal regulatory protein family interactions	R-HSA-391160	7.088300e-01	0.149	0	0
Uptake and actions of bacterial toxins	R-HSA-5339562	4.448797e-01	0.352	0	0
Physiological factors	R-HSA-5578768	2.381821e-01	0.623	0	0
Kidney development	R-HSA-9830369	7.041871e-01	0.152	0	0
ChREBP activates metabolic gene expression	R-HSA-163765	5.746065e-01	0.241	0	0
Activation of gene expression by SREBF (SREBP)	R-HSA-2426168	5.149711e-01	0.288	0	0
TYSND1 cleaves peroxisomal proteins	R-HSA-9033500	6.680189e-01	0.175	0	0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	R-HSA-9926550	6.138518e-01	0.212	0	0
Sensory processing of sound by outer hair cells of the cochlea	R-HSA-9662361	3.887408e-01	0.410	0	0
Nectin/Necl trans heterodimerization	R-HSA-420597	6.189454e-01	0.208	0	0
MAP3K8 (TPL2)-dependent MAPK1/3 activation	R-HSA-5684264	7.088300e-01	0.149	0	0
Maturation of nucleoprotein	R-HSA-9683610	6.790125e-01	0.168	0	0
Replication of the SARS-CoV-1 genome	R-HSA-9682706	6.790125e-01	0.168	0	0
SARS-CoV-1 Genome Replication and Transcription	R-HSA-9679514	7.088300e-01	0.149	0	0
BMAL1:CLOCK,NPAS2 activates circadian expression	R-HSA-1368108	4.967102e-01	0.304	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9679504	6.138518e-01	0.212	0	0
DNA methylation	R-HSA-5334118	7.095443e-01	0.149	0	0
Endosomal Sorting Complex Required For Transport (ESCRT)	R-HSA-917729	7.095443e-01	0.149	0	0
mRNA Capping	R-HSA-72086	7.095443e-01	0.149	0	0
Nitric oxide stimulates guanylate cyclase	R-HSA-392154	7.095443e-01	0.149	0	0
Host Interactions of HIV factors	R-HSA-162909	7.102362e-01	0.149	0	0
Activation of NIMA Kinases NEK9, NEK6, NEK7	R-HSA-2980767	7.107750e-01	0.148	0	0
Signaling by LTK in cancer	R-HSA-9842640	7.107750e-01	0.148	0	0
Erythropoietin activates STAT5	R-HSA-9027283	7.107750e-01	0.148	0	0
STAT5 Activation	R-HSA-9645135	7.107750e-01	0.148	0	0
Autointegration results in viral DNA circles	R-HSA-177539	7.107750e-01	0.148	0	0
Metabolism of ingested MeSeO2H into MeSeH	R-HSA-5263617	7.107750e-01	0.148	0	0
Defective CHST14 causes EDS, musculocontractural type	R-HSA-3595174	7.107750e-01	0.148	0	0
Small interfering RNA (siRNA) biogenesis	R-HSA-426486	7.107750e-01	0.148	0	0
Signaling by TGF-beta Receptor Complex in Cancer	R-HSA-3304351	7.107750e-01	0.148	0	0
Intracellular metabolism of fatty acids regulates insulin secretion	R-HSA-434313	7.107750e-01	0.148	0	0
Integration of viral DNA into host genomic DNA	R-HSA-175567	7.107750e-01	0.148	0	0
CREB phosphorylation	R-HSA-199920	7.107750e-01	0.148	0	0
NADPH regeneration	R-HSA-389542	7.107750e-01	0.148	0	0
HDL clearance	R-HSA-8964011	7.107750e-01	0.148	0	0
Neurofascin interactions	R-HSA-447043	7.107750e-01	0.148	0	0
Cellular responses to stress	R-HSA-2262752	7.150925e-01	0.146	0	0
Unblocking of NMDA receptors, glutamate binding and activation	R-HSA-438066	7.182804e-01	0.144	0	0
SHC-mediated cascade:FGFR4	R-HSA-5654719	7.182804e-01	0.144	0	0
Ras activation upon Ca2+ influx through NMDA receptor	R-HSA-442982	7.182804e-01	0.144	0	0
Listeria monocytogenes entry into host cells	R-HSA-8876384	7.182804e-01	0.144	0	0
Glutathione synthesis and recycling	R-HSA-174403	7.182804e-01	0.144	0	0
Negative regulation of NMDA receptor-mediated neuronal transmission	R-HSA-9617324	7.182804e-01	0.144	0	0
Signaling by NTRK3 (TRKC)	R-HSA-9034015	7.182804e-01	0.144	0	0
Assembly Of The HIV Virion	R-HSA-175474	7.182804e-01	0.144	0	0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	R-HSA-174184	7.187367e-01	0.143	0	0
Formation of RNA Pol II elongation complex	R-HSA-112382	7.187367e-01	0.143	0	0
E3 ubiquitin ligases ubiquitinate target proteins	R-HSA-8866654	7.187367e-01	0.143	0	0
TRAF6 mediated IRF7 activation	R-HSA-933541	7.236861e-01	0.140	0	0
Inositol phosphate metabolism	R-HSA-1483249	7.270296e-01	0.138	0	0
Downregulation of ERBB2 signaling	R-HSA-8863795	7.297432e-01	0.137	0	0
NR1H2 and NR1H3-mediated signaling	R-HSA-9024446	7.323113e-01	0.135	0	0
IRS-related events triggered by IGF1R	R-HSA-2428928	7.327466e-01	0.135	0	0
Oncogenic MAPK signaling	R-HSA-6802957	7.328628e-01	0.135	0	0
RNA Polymerase II Transcription Elongation	R-HSA-75955	7.341460e-01	0.134	0	0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	R-HSA-179419	7.341460e-01	0.134	0	0
Meiotic synapsis	R-HSA-1221632	7.341460e-01	0.134	0	0
PTEN Regulation	R-HSA-6807070	7.352782e-01	0.134	0	0
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	7.362617e-01	0.133	0	0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	R-HSA-8948700	7.362940e-01	0.133	0	0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	R-HSA-2173791	7.362940e-01	0.133	0	0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	R-HSA-450385	7.362940e-01	0.133	0	0
SHC1 events in EGFR signaling	R-HSA-180336	7.362940e-01	0.133	0	0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	R-HSA-450513	7.362940e-01	0.133	0	0
Beta-catenin phosphorylation cascade	R-HSA-196299	7.362940e-01	0.133	0	0
Signaling by Activin	R-HSA-1502540	7.362940e-01	0.133	0	0
p75NTR signals via NF-kB	R-HSA-193639	7.362940e-01	0.133	0	0
p38MAPK events	R-HSA-171007	7.362940e-01	0.133	0	0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	R-HSA-9735871	7.362940e-01	0.133	0	0
InlB-mediated entry of Listeria monocytogenes into host cell	R-HSA-8875360	7.362940e-01	0.133	0	0
Protein methylation	R-HSA-8876725	7.362940e-01	0.133	0	0
IRF3-mediated induction of type I IFN	R-HSA-3270619	7.362940e-01	0.133	0	0
Signaling by FGFR3	R-HSA-5654741	7.367985e-01	0.133	0	0
Vasopressin regulates renal water homeostasis via Aquaporins	R-HSA-432040	7.367985e-01	0.133	0	0
DAG and IP3 signaling	R-HSA-1489509	7.367985e-01	0.133	0	0
Signaling by WNT	R-HSA-195721	7.406523e-01	0.130	0	0
RAF-independent MAPK1/3 activation	R-HSA-112409	7.406617e-01	0.130	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9694676	7.406617e-01	0.130	0	0
Nuclear Receptor transcription pathway	R-HSA-383280	7.450250e-01	0.128	0	0
Regulation of APC/C activators between G1/S and early anaphase	R-HSA-176408	7.467655e-01	0.127	0	0
Synthesis of PIPs at the plasma membrane	R-HSA-1660499	7.467655e-01	0.127	0	0
Signaling by PDGF	R-HSA-186797	7.467655e-01	0.127	0	0
RUNX3 Regulates Immune Response and Cell Migration	R-HSA-8949275	7.480267e-01	0.126	0	0
MET activates PI3K/AKT signaling	R-HSA-8851907	7.480267e-01	0.126	0	0
Glycoprotein hormones	R-HSA-209822	7.480267e-01	0.126	0	0
IFNG signaling activates MAPKs	R-HSA-9732724	7.480267e-01	0.126	0	0
Pre-NOTCH Processing in the Endoplasmic Reticulum	R-HSA-1912399	7.480267e-01	0.126	0	0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	R-HSA-2892245	7.480267e-01	0.126	0	0
PTK6 Expression	R-HSA-8849473	7.480267e-01	0.126	0	0
Activated NTRK2 signals through CDK5	R-HSA-9032845	7.480267e-01	0.126	1	1
Cysteine formation from homocysteine	R-HSA-1614603	7.480267e-01	0.126	0	0
DAG1 core M1 glycosylations	R-HSA-8932506	7.480267e-01	0.126	0	0
VLDL clearance	R-HSA-8964046	7.480267e-01	0.126	0	0
Cation-coupled Chloride cotransporters	R-HSA-426117	7.480267e-01	0.126	0	0
CHL1 interactions	R-HSA-447041	7.480267e-01	0.126	0	0
Downstream signal transduction	R-HSA-186763	7.488705e-01	0.126	0	0
Translation initiation complex formation	R-HSA-72649	7.489581e-01	0.126	0	0
Autodegradation of Cdh1 by Cdh1:APC/C	R-HSA-174084	7.525289e-01	0.123	0	0
Glycolysis	R-HSA-70171	7.570616e-01	0.121	0	0
Gene Silencing by RNA	R-HSA-211000	7.576294e-01	0.121	0	0
NoRC negatively regulates rRNA expression	R-HSA-427413	7.584059e-01	0.120	0	0
Membrane Trafficking	R-HSA-199991	7.591392e-01	0.120	0	0
Nuclear events mediated by NFE2L2	R-HSA-9759194	7.593771e-01	0.120	0	0
Semaphorin interactions	R-HSA-373755	7.602630e-01	0.119	1	0
TP53 Regulates Transcription of Caspase Activators and Caspases	R-HSA-6803207	7.615158e-01	0.118	0	0
Regulation of BACH1 activity	R-HSA-9708530	7.615158e-01	0.118	0	0
Regulation of NF-kappa B signaling	R-HSA-9758274	7.615158e-01	0.118	0	0
Negative regulation of FLT3	R-HSA-9706369	7.615158e-01	0.118	0	0
Activation of SMO	R-HSA-5635838	7.615158e-01	0.118	0	0
Induction of Cell-Cell Fusion	R-HSA-9733458	7.615158e-01	0.118	0	0
Receptor-type tyrosine-protein phosphatases	R-HSA-388844	7.615158e-01	0.118	0	0
Prefoldin mediated transfer of substrate to CCT/TriC	R-HSA-389957	7.616052e-01	0.118	0	0
Growth hormone receptor signaling	R-HSA-982772	7.616052e-01	0.118	0	0
Syndecan interactions	R-HSA-3000170	7.616052e-01	0.118	0	0
COPI-independent Golgi-to-ER retrograde traffic	R-HSA-6811436	7.631737e-01	0.117	0	0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells	R-HSA-9937080	7.669423e-01	0.115	0	0
Recognition and association of DNA glycosylase with site containing an affected purine	R-HSA-110330	7.669423e-01	0.115	0	0
Retrograde transport at the Trans-Golgi-Network	R-HSA-6811440	7.675628e-01	0.115	0	0
Regulation of PD-L1(CD274) expression	R-HSA-9909648	7.688864e-01	0.114	0	0
Insulin receptor signalling cascade	R-HSA-74751	7.732402e-01	0.112	0	0
Inhibition of DNA recombination at telomere	R-HSA-9670095	7.741102e-01	0.111	0	0
Formation of Incision Complex in GG-NER	R-HSA-5696395	7.741102e-01	0.111	0	0
Ribosomal scanning and start codon recognition	R-HSA-72702	7.767955e-01	0.110	0	0
Activated NTRK2 signals through PI3K	R-HSA-9028335	7.804823e-01	0.108	0	0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	R-HSA-8939242	7.804823e-01	0.108	0	0
Nef mediated downregulation of MHC class I complex cell surface expression	R-HSA-164940	7.804823e-01	0.108	0	0
Interleukin-9 signaling	R-HSA-8985947	7.804823e-01	0.108	0	0
Axonal growth inhibition (RHOA activation)	R-HSA-193634	7.804823e-01	0.108	0	0
DAG1 core M2 glycosylations	R-HSA-8932504	7.804823e-01	0.108	0	0
TGFBR3 PTM regulation	R-HSA-9839383	7.804823e-01	0.108	0	0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	R-HSA-442729	7.804823e-01	0.108	0	0
SHC-mediated cascade:FGFR1	R-HSA-5654688	7.811549e-01	0.107	0	0
Formation of tubulin folding intermediates by CCT/TriC	R-HSA-389960	7.811549e-01	0.107	0	0
CD209 (DC-SIGN) signaling	R-HSA-5621575	7.811549e-01	0.107	0	0
KEAP1-NFE2L2 pathway	R-HSA-9755511	7.813278e-01	0.107	0	0
Assembly of the ORC complex at the origin of replication	R-HSA-68616	7.839802e-01	0.106	0	0
Synthesis of IP3 and IP4 in the cytosol	R-HSA-1855204	7.839802e-01	0.106	0	0
GRB2 events in ERBB2 signaling	R-HSA-1963640	7.846174e-01	0.105	0	0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	R-HSA-936964	7.846174e-01	0.105	0	0
Transcriptional regulation of testis differentiation	R-HSA-9690406	7.846174e-01	0.105	0	0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	R-HSA-400511	7.846174e-01	0.105	0	0
Cellular response to hypoxia	R-HSA-1234174	7.856999e-01	0.105	0	0
TRIF (TICAM1)-mediated TLR4 signaling	R-HSA-937061	7.874453e-01	0.104	0	0
MyD88-independent TLR4 cascade	R-HSA-166166	7.874453e-01	0.104	0	0
Chromatin modifications during the maternal to zygotic transition (MZT)	R-HSA-9821002	7.892601e-01	0.103	0	0
IRS-mediated signalling	R-HSA-112399	7.898290e-01	0.102	0	0
Senescence-Associated Secretory Phenotype (SASP)	R-HSA-2559582	7.917196e-01	0.101	0	0
Signaling by FGFR in disease	R-HSA-1226099	7.942250e-01	0.100	0	0
Cellular responses to stimuli	R-HSA-8953897	7.967250e-01	0.099	0	0
Response of endothelial cells to shear stress	R-HSA-9860931	7.975163e-01	0.098	0	0
COPI-mediated anterograde transport	R-HSA-6807878	7.986253e-01	0.098	0	0
Sema4D in semaphorin signaling	R-HSA-400685	7.993614e-01	0.097	0	0
Formation of the nephric duct	R-HSA-9830364	7.993614e-01	0.097	0	0
Glucagon signaling in metabolic regulation	R-HSA-163359	8.000108e-01	0.097	0	0
MAPK family signaling cascades	R-HSA-5683057	8.046762e-01	0.094	0	0
Protein ubiquitination	R-HSA-8852135	8.052508e-01	0.094	0	0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se	R-HSA-2408550	8.057264e-01	0.094	0	0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	R-HSA-164938	8.057264e-01	0.094	0	0
Regulation of NPAS4 gene expression	R-HSA-9768759	8.057264e-01	0.094	0	0
Replication of the SARS-CoV-2 genome	R-HSA-9694686	8.057264e-01	0.094	0	0
Nonsense-Mediated Decay (NMD)	R-HSA-927802	8.058318e-01	0.094	0	0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	R-HSA-975957	8.058318e-01	0.094	0	0
Telomere Maintenance	R-HSA-157579	8.082261e-01	0.092	0	0
PI3K Cascade	R-HSA-109704	8.085647e-01	0.092	0	0
Azathioprine ADME	R-HSA-9748787	8.085647e-01	0.092	0	0
IRAK2 mediated activation of TAK1 complex	R-HSA-937042	8.087591e-01	0.092	0	0
Interleukin-21 signaling	R-HSA-9020958	8.087591e-01	0.092	0	0
AMPK inhibits chREBP transcriptional activation activity	R-HSA-163680	8.087591e-01	0.092	0	0
MASTL Facilitates Mitotic Progression	R-HSA-2465910	8.087591e-01	0.092	0	0
Unwinding of DNA	R-HSA-176974	8.087591e-01	0.092	0	0
Activation of the AP-1 family of transcription factors	R-HSA-450341	8.087591e-01	0.092	0	0
p75NTR regulates axonogenesis	R-HSA-193697	8.087591e-01	0.092	0	0
mRNA Editing	R-HSA-75072	8.087591e-01	0.092	0	0
Activation of RAC1 downstream of NMDARs	R-HSA-9619229	8.087591e-01	0.092	0	0
Regulation of signaling by NODAL	R-HSA-1433617	8.087591e-01	0.092	0	0
MAPK1 (ERK2) activation	R-HSA-112411	8.087591e-01	0.092	0	0
Lipophagy	R-HSA-9613354	8.087591e-01	0.092	0	0
Regulated proteolysis of p75NTR	R-HSA-193692	8.087591e-01	0.092	0	0
Butyrophilin (BTN) family interactions	R-HSA-8851680	8.087591e-01	0.092	0	0
RUNX1 regulates transcription of genes involved in differentiation of HSCs	R-HSA-8939236	8.125904e-01	0.090	0	0
PPARA activates gene expression	R-HSA-1989781	8.126586e-01	0.090	0	0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	R-HSA-6814122	8.150644e-01	0.089	0	0
Signaling by EGFR in Cancer	R-HSA-1643713	8.162804e-01	0.088	0	0
Metalloprotease DUBs	R-HSA-5689901	8.162804e-01	0.088	0	0
Attachment of bacteria to epithelial cells	R-HSA-9638630	8.162804e-01	0.088	0	0
Urea cycle	R-HSA-70635	8.162804e-01	0.088	0	0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells	R-HSA-9927418	8.171663e-01	0.088	0	0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	R-HSA-381676	8.171663e-01	0.088	0	0
Ca-dependent events	R-HSA-111996	8.171663e-01	0.088	0	0
MyD88 cascade initiated on plasma membrane	R-HSA-975871	8.174862e-01	0.088	0	0
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	8.174862e-01	0.088	0	0
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	8.174862e-01	0.088	0	0
Collagen biosynthesis and modifying enzymes	R-HSA-1650814	8.200282e-01	0.086	0	0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	R-HSA-1234176	8.209045e-01	0.086	0	0
Cellular responses to mechanical stimuli	R-HSA-9855142	8.230392e-01	0.085	0	0
Vitamin D (calciferol) metabolism	R-HSA-196791	8.249728e-01	0.084	0	0
Nephron development	R-HSA-9831926	8.249728e-01	0.084	0	0
Regulation of lipid metabolism by PPARalpha	R-HSA-400206	8.270665e-01	0.082	0	0
EPH-Ephrin signaling	R-HSA-2682334	8.288176e-01	0.082	0	0
Signaling by SCF-KIT	R-HSA-1433557	8.299640e-01	0.081	0	0
SHC-mediated cascade:FGFR2	R-HSA-5654699	8.319712e-01	0.080	0	0
Disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	8.319712e-01	0.080	0	0
Signaling by FGFR3 in disease	R-HSA-5655332	8.319712e-01	0.080	0	0
Maturation of hRSV A proteins	R-HSA-9828806	8.319712e-01	0.080	0	0
Cell-cell junction organization	R-HSA-421270	8.323491e-01	0.080	0	0
SARS-CoV-1 activates/modulates innate immune responses	R-HSA-9692916	8.326052e-01	0.080	0	0
Erythropoietin activates Phospholipase C gamma (PLCG)	R-HSA-9027277	8.333949e-01	0.079	0	0
Peptide hormone biosynthesis	R-HSA-209952	8.333949e-01	0.079	0	0
PI3K/AKT activation	R-HSA-198203	8.333949e-01	0.079	0	0
Interleukin-27 signaling	R-HSA-9020956	8.333949e-01	0.079	0	0
Metal sequestration by antimicrobial proteins	R-HSA-6799990	8.333949e-01	0.079	0	0
EGFR Transactivation by Gastrin	R-HSA-2179392	8.333949e-01	0.079	0	0
2-LTR circle formation	R-HSA-164843	8.333949e-01	0.079	0	0
Arachidonate production from DAG	R-HSA-426048	8.333949e-01	0.079	0	0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	R-HSA-428359	8.333949e-01	0.079	0	0
Sperm Motility And Taxes	R-HSA-1300642	8.333949e-01	0.079	0	0
CaMK IV-mediated phosphorylation of CREB	R-HSA-111932	8.333949e-01	0.079	0	0
Signaling by Leptin	R-HSA-2586552	8.333949e-01	0.079	0	0
Formation of paraxial mesoderm	R-HSA-9793380	8.362522e-01	0.078	0	0
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	8.390889e-01	0.076	0	0
Degradation of beta-catenin by the destruction complex	R-HSA-195253	8.404498e-01	0.075	0	0
Cytosolic sensors of pathogen-associated DNA	R-HSA-1834949	8.404498e-01	0.075	0	0
XBP1(S) activates chaperone genes	R-HSA-381038	8.408944e-01	0.075	0	0
PI-3K cascade:FGFR3	R-HSA-5654710	8.424860e-01	0.074	0	0
Germ layer formation at gastrulation	R-HSA-9754189	8.424860e-01	0.074	0	0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes	R-HSA-9856532	8.424860e-01	0.074	0	0
Regulation of signaling by CBL	R-HSA-912631	8.424860e-01	0.074	0	0
STING mediated induction of host immune responses	R-HSA-1834941	8.424860e-01	0.074	0	0
SARS-CoV-2 Genome Replication and Transcription	R-HSA-9694682	8.424860e-01	0.074	0	0
Maturation of nucleoprotein	R-HSA-9694631	8.424860e-01	0.074	0	0
Signaling by Nuclear Receptors	R-HSA-9006931	8.450176e-01	0.073	0	0
Collagen formation	R-HSA-1474290	8.460914e-01	0.073	0	0
NCAM signaling for neurite out-growth	R-HSA-375165	8.464873e-01	0.072	0	0
Formation of the Early Elongation Complex	R-HSA-113418	8.464953e-01	0.072	0	0
Activation of AMPK downstream of NMDARs	R-HSA-9619483	8.464953e-01	0.072	0	0
Formation of the HIV-1 Early Elongation Complex	R-HSA-167158	8.464953e-01	0.072	0	0
Pyrimidine salvage	R-HSA-73614	8.464953e-01	0.072	0	0
Post NMDA receptor activation events	R-HSA-438064	8.495540e-01	0.071	0	0
Transcriptional and post-translational regulation of MITF-M expression and activity	R-HSA-9856649	8.499510e-01	0.071	0	0
SARS-CoV-2 modulates host translation machinery	R-HSA-9754678	8.541601e-01	0.068	0	0
Base-Excision Repair, AP Site Formation	R-HSA-73929	8.541601e-01	0.068	0	0
Signaling by high-kinase activity BRAF mutants	R-HSA-6802948	8.547109e-01	0.068	0	0
Voltage gated Potassium channels	R-HSA-1296072	8.547109e-01	0.068	0	0
Cleavage of the damaged purine	R-HSA-110331	8.547109e-01	0.068	0	0
NCAM1 interactions	R-HSA-419037	8.547109e-01	0.068	0	0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	R-HSA-933543	8.548583e-01	0.068	0	0
InlA-mediated entry of Listeria monocytogenes into host cells	R-HSA-8876493	8.548583e-01	0.068	0	0
CD163 mediating an anti-inflammatory response	R-HSA-9662834	8.548583e-01	0.068	0	0
vRNA Synthesis	R-HSA-192814	8.548583e-01	0.068	0	0
Hormone ligand-binding receptors	R-HSA-375281	8.548583e-01	0.068	0	0
Synthesis of PI	R-HSA-1483226	8.548583e-01	0.068	0	0
Bicarbonate transporters	R-HSA-425381	8.548583e-01	0.068	0	0
DAG1 core M3 glycosylations	R-HSA-8932505	8.548583e-01	0.068	0	0
Transport of RCbl within the body	R-HSA-9758890	8.548583e-01	0.068	0	0
Chylomicron assembly	R-HSA-8963888	8.548583e-01	0.068	0	0
Inorganic anion exchange by SLC26 transporters	R-HSA-427601	8.548583e-01	0.068	0	0
PECAM1 interactions	R-HSA-210990	8.548583e-01	0.068	0	0
G1/S DNA Damage Checkpoints	R-HSA-69615	8.562015e-01	0.067	0	0
Regulation of PD-L1(CD274) translation	R-HSA-9909620	8.583931e-01	0.066	0	0
PI-3K cascade:FGFR4	R-HSA-5654720	8.583931e-01	0.066	0	0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	R-HSA-9609523	8.583931e-01	0.066	0	0
Signal transduction by L1	R-HSA-445144	8.583931e-01	0.066	0	0
Nephrin family interactions	R-HSA-373753	8.583931e-01	0.066	0	0
Regulation of gene expression in beta cells	R-HSA-210745	8.599152e-01	0.066	0	0
Signaling by moderate kinase activity BRAF mutants	R-HSA-6802946	8.640259e-01	0.063	0	0
Paradoxical activation of RAF signaling by kinase inactive BRAF	R-HSA-6802955	8.640259e-01	0.063	0	0
Signaling downstream of RAS mutants	R-HSA-9649948	8.640259e-01	0.063	0	0
Signaling by RAS mutants	R-HSA-6802949	8.640259e-01	0.063	0	0
Metabolism of nitric oxide: NOS3 activation and regulation	R-HSA-202131	8.662135e-01	0.062	0	0
Depurination	R-HSA-73927	8.662135e-01	0.062	0	0
PI3K/AKT Signaling in Cancer	R-HSA-2219528	8.678386e-01	0.062	0	0
Signaling by ROBO receptors	R-HSA-376176	8.682121e-01	0.061	0	0
Acetylcholine Neurotransmitter Release Cycle	R-HSA-264642	8.728172e-01	0.059	0	0
Early Phase of HIV Life Cycle	R-HSA-162594	8.728172e-01	0.059	0	0
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	8.733308e-01	0.059	0	0
Signaling by FGFR1	R-HSA-5654736	8.733820e-01	0.059	0	0
ATF6 (ATF6-alpha) activates chaperone genes	R-HSA-381183	8.735577e-01	0.059	0	0
Synthesis of diphthamide-EEF2	R-HSA-5358493	8.735577e-01	0.059	0	0
PI3K events in ERBB4 signaling	R-HSA-1250342	8.735577e-01	0.059	0	0
Integration of provirus	R-HSA-162592	8.735577e-01	0.059	0	0
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	R-HSA-3772470	8.735577e-01	0.059	0	0
Plasmalogen biosynthesis	R-HSA-75896	8.735577e-01	0.059	0	0
NF-kB is activated and signals survival	R-HSA-209560	8.735577e-01	0.059	0	0
ERKs are inactivated	R-HSA-202670	8.735577e-01	0.059	0	0
APOBEC3G mediated resistance to HIV-1 infection	R-HSA-180689	8.735577e-01	0.059	0	0
Proton-coupled monocarboxylate transport	R-HSA-433692	8.735577e-01	0.059	0	0
DS-GAG biosynthesis	R-HSA-2022923	8.735577e-01	0.059	0	0
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	8.740246e-01	0.058	0	0
Recycling pathway of L1	R-HSA-437239	8.740246e-01	0.058	0	0
Signaling by BRAF and RAF1 fusions	R-HSA-6802952	8.741289e-01	0.058	0	0
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	8.768946e-01	0.057	0	0
Formation of HIV-1 elongation complex containing HIV-1 Tat	R-HSA-167200	8.769249e-01	0.057	0	0
Stabilization of p53	R-HSA-69541	8.769249e-01	0.057	0	0
Regulation of TP53 Expression and Degradation	R-HSA-6806003	8.769249e-01	0.057	0	0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	R-HSA-9725554	8.769249e-01	0.057	0	0
Transcriptional Regulation by E2F6	R-HSA-8953750	8.769249e-01	0.057	0	0
Trafficking of AMPA receptors	R-HSA-399719	8.836944e-01	0.054	0	0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	R-HSA-389958	8.836944e-01	0.054	0	0
Negative regulators of DDX58/IFIH1 signaling	R-HSA-936440	8.836944e-01	0.054	0	0
Cargo concentration in the ER	R-HSA-5694530	8.836944e-01	0.054	0	0
Evasion by RSV of host interferon responses	R-HSA-9833109	8.836944e-01	0.054	0	0
FRS-mediated FGFR3 signaling	R-HSA-5654706	8.858763e-01	0.053	0	0
Mitochondrial calcium ion transport	R-HSA-8949215	8.858763e-01	0.053	0	0
SARS-CoV-1-host interactions	R-HSA-9692914	8.862889e-01	0.052	0	0
Regulation of RUNX3 expression and activity	R-HSA-8941858	8.868851e-01	0.052	0	0
Formation of HIV elongation complex in the absence of HIV Tat	R-HSA-167152	8.868851e-01	0.052	0	0
Tat-mediated elongation of the HIV-1 transcript	R-HSA-167246	8.868851e-01	0.052	0	0
HIV Transcription Elongation	R-HSA-167169	8.868851e-01	0.052	0	0
IRE1alpha activates chaperones	R-HSA-381070	8.874065e-01	0.052	0	0
IRAK1 recruits IKK complex	R-HSA-937039	8.898489e-01	0.051	0	0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	R-HSA-975144	8.898489e-01	0.051	0	0
GRB2 events in EGFR signaling	R-HSA-179812	8.898489e-01	0.051	0	0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA	R-HSA-77305	8.898489e-01	0.051	0	0
Beta oxidation of myristoyl-CoA to lauroyl-CoA	R-HSA-77285	8.898489e-01	0.051	0	0
Serotonin clearance from the synaptic cleft	R-HSA-380615	8.898489e-01	0.051	0	0
Interleukin-35 Signalling	R-HSA-8984722	8.898489e-01	0.051	0	0
Advanced glycosylation endproduct receptor signaling	R-HSA-879415	8.898489e-01	0.051	0	0
Regulation of IFNG signaling	R-HSA-877312	8.898489e-01	0.051	0	0
Reversal of alkylation damage by DNA dioxygenases	R-HSA-73943	8.898489e-01	0.051	0	0
OAS antiviral response	R-HSA-8983711	8.898489e-01	0.051	0	0
Early SARS-CoV-2 Infection Events	R-HSA-9772572	8.904367e-01	0.050	0	0
Signaling by NOTCH	R-HSA-157118	8.945927e-01	0.048	0	0
Signaling by Interleukins	R-HSA-449147	8.955109e-01	0.048	0	0
Class I MHC mediated antigen processing & presentation	R-HSA-983169	8.958984e-01	0.048	0	0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	8.961338e-01	0.048	0	0
PI-3K cascade:FGFR1	R-HSA-5654689	8.976826e-01	0.047	0	0
Developmental Lineage of Mammary Stem Cells	R-HSA-9938206	8.976826e-01	0.047	0	0
FRS-mediated FGFR4 signaling	R-HSA-5654712	8.976826e-01	0.047	0	0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	8.983003e-01	0.047	0	0
Stimuli-sensing channels	R-HSA-2672351	8.983003e-01	0.047	0	0
Sealing of the nuclear envelope (NE) by ESCRT-III	R-HSA-9668328	9.038039e-01	0.044	0	0
Glutamate binding, activation of AMPA receptors and synaptic plasticity	R-HSA-399721	9.038039e-01	0.044	0	0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	R-HSA-442742	9.038039e-01	0.044	0	0
Regulation of necroptotic cell death	R-HSA-5675482	9.038039e-01	0.044	0	0
MyD88 dependent cascade initiated on endosome	R-HSA-975155	9.039028e-01	0.044	0	0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	R-HSA-8877330	9.040420e-01	0.044	0	0
ATF6 (ATF6-alpha) activates chaperones	R-HSA-381033	9.040420e-01	0.044	0	0
CD28 dependent Vav1 pathway	R-HSA-389359	9.040420e-01	0.044	0	0
Chylomicron remodeling	R-HSA-8963901	9.040420e-01	0.044	0	0
Acyl chain remodeling of DAG and TAG	R-HSA-1482883	9.040420e-01	0.044	0	0
CREB1 phosphorylation through the activation of Adenylate Cyclase	R-HSA-442720	9.040420e-01	0.044	0	0
Processing of SMDT1	R-HSA-8949664	9.040420e-01	0.044	0	0
MAP2K and MAPK activation	R-HSA-5674135	9.047104e-01	0.043	0	0
Signaling by RAF1 mutants	R-HSA-9656223	9.047104e-01	0.043	0	0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	R-HSA-9615017	9.047104e-01	0.043	0	0
Assembly and cell surface presentation of NMDA receptors	R-HSA-9609736	9.047104e-01	0.043	0	0
RNA polymerase II transcribes snRNA genes	R-HSA-6807505	9.049967e-01	0.043	0	0
Glutathione conjugation	R-HSA-156590	9.054965e-01	0.043	0	0
Activation of NMDA receptors and postsynaptic events	R-HSA-442755	9.075526e-01	0.042	0	0
Regulation of PTEN mRNA translation	R-HSA-8943723	9.083421e-01	0.042	0	0
The role of Nef in HIV-1 replication and disease pathogenesis	R-HSA-164952	9.083421e-01	0.042	0	0
Carnitine shuttle	R-HSA-200425	9.083421e-01	0.042	0	0
Mitochondrial mRNA modification	R-HSA-9937008	9.083421e-01	0.042	0	0
Ketone body metabolism	R-HSA-74182	9.083421e-01	0.042	0	0
Influenza Viral RNA Transcription and Replication	R-HSA-168273	9.089924e-01	0.041	0	0
ER to Golgi Anterograde Transport	R-HSA-199977	9.108187e-01	0.041	0	0
COPII-mediated vesicle transport	R-HSA-204005	9.109687e-01	0.040	0	0
Glucose metabolism	R-HSA-70326	9.111130e-01	0.040	0	0
PLC beta mediated events	R-HSA-112043	9.123326e-01	0.040	0	0
Aquaporin-mediated transport	R-HSA-445717	9.123326e-01	0.040	0	0
Effects of PIP2 hydrolysis	R-HSA-114508	9.126311e-01	0.040	0	0
Miscellaneous transport and binding events	R-HSA-5223345	9.126311e-01	0.040	0	0
Intracellular signaling by second messengers	R-HSA-9006925	9.138585e-01	0.039	0	0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)	R-HSA-9931269	9.151161e-01	0.039	0	0
RNA Polymerase I Promoter Escape	R-HSA-73772	9.151161e-01	0.039	0	0
Transcriptional Regulation by NPAS4	R-HSA-9634815	9.151161e-01	0.039	1	0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	R-HSA-975163	9.164069e-01	0.038	0	0
Synthesis of IPs in the nucleus	R-HSA-1855191	9.164069e-01	0.038	0	0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA	R-HSA-77350	9.164069e-01	0.038	0	0
cGMP effects	R-HSA-418457	9.164069e-01	0.038	0	0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	R-HSA-77310	9.164069e-01	0.038	0	0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	R-HSA-77348	9.164069e-01	0.038	0	0
HDL assembly	R-HSA-8963896	9.164069e-01	0.038	0	0
Acyl chain remodeling of CL	R-HSA-1482798	9.164069e-01	0.038	0	0
P2Y receptors	R-HSA-417957	9.164069e-01	0.038	0	0
PIP3 activates AKT signaling	R-HSA-1257604	9.177305e-01	0.037	0	0
Replacement of protamines by nucleosomes in the male pronucleus	R-HSA-9821993	9.179543e-01	0.037	0	0
Signaling by FLT3 ITD and TKD mutants	R-HSA-9703648	9.179543e-01	0.037	0	0
Norepinephrine Neurotransmitter Release Cycle	R-HSA-181430	9.179543e-01	0.037	0	0
Mitochondrial RNA degradation	R-HSA-9836573	9.179543e-01	0.037	0	0
TNFs bind their physiological receptors	R-HSA-5669034	9.179543e-01	0.037	0	0
Plasma lipoprotein assembly	R-HSA-8963898	9.179543e-01	0.037	0	0
Assembly of active LPL and LIPC lipase complexes	R-HSA-8963889	9.179543e-01	0.037	0	0
Response of EIF2AK4 (GCN2) to amino acid deficiency	R-HSA-9633012	9.179915e-01	0.037	0	0
Response of Mtb to phagocytosis	R-HSA-9637690	9.200007e-01	0.036	0	0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	R-HSA-166058	9.205950e-01	0.036	0	0
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	9.205950e-01	0.036	0	0
Developmental Lineage of Mammary Gland Alveolar Cells	R-HSA-9927426	9.207152e-01	0.036	0	0
SARS-CoV-1 modulates host translation machinery	R-HSA-9735869	9.207152e-01	0.036	0	0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	R-HSA-983170	9.207152e-01	0.036	0	0
NPAS4 regulates expression of target genes	R-HSA-9768919	9.207152e-01	0.036	1	1
Golgi Associated Vesicle Biogenesis	R-HSA-432722	9.217513e-01	0.035	0	0
Smooth Muscle Contraction	R-HSA-445355	9.217513e-01	0.035	0	0
rRNA modification in the nucleus and cytosol	R-HSA-6790901	9.247249e-01	0.034	0	0
Co-inhibition by PD-1	R-HSA-389948	9.253672e-01	0.034	0	0
SARS-CoV-1 Infection	R-HSA-9678108	9.257741e-01	0.033	0	0
PI-3K cascade:FGFR2	R-HSA-5654695	9.266119e-01	0.033	0	0
FRS-mediated FGFR1 signaling	R-HSA-5654693	9.266119e-01	0.033	0	0
MicroRNA (miRNA) biogenesis	R-HSA-203927	9.266119e-01	0.033	0	0
Acyl chain remodelling of PS	R-HSA-1482801	9.266119e-01	0.033	0	0
SCF(Skp2)-mediated degradation of p27/p21	R-HSA-187577	9.267889e-01	0.033	0	0
Amine ligand-binding receptors	R-HSA-375280	9.267889e-01	0.033	0	0
Activation of BAD and translocation to mitochondria	R-HSA-111447	9.271792e-01	0.033	0	0
Sema3A PAK dependent Axon repulsion	R-HSA-399954	9.271792e-01	0.033	0	0
Transport and metabolism of PAPS	R-HSA-174362	9.271792e-01	0.033	0	0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	R-HSA-9673767	9.271792e-01	0.033	0	0
Signaling by PDGFRA extracellular domain mutants	R-HSA-9673770	9.271792e-01	0.033	0	0
FASTK family proteins regulate processing and stability of mitochondrial RNAs	R-HSA-9837092	9.271792e-01	0.033	0	0
Lysosphingolipid and LPA receptors	R-HSA-419408	9.271792e-01	0.033	0	0
Spry regulation of FGF signaling	R-HSA-1295596	9.271792e-01	0.033	0	0
TRAF6-mediated induction of TAK1 complex within TLR4 complex	R-HSA-937072	9.271792e-01	0.033	0	0
Other semaphorin interactions	R-HSA-416700	9.271792e-01	0.033	0	0
DNA Damage Reversal	R-HSA-73942	9.271792e-01	0.033	0	0
SCF-beta-TrCP mediated degradation of Emi1	R-HSA-174113	9.281096e-01	0.032	0	0
Ca2+ pathway	R-HSA-4086398	9.282916e-01	0.032	0	0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	9.303233e-01	0.031	0	0
SARS-CoV-2 Infection	R-HSA-9694516	9.329249e-01	0.030	0	0
Fanconi Anemia Pathway	R-HSA-6783310	9.330533e-01	0.030	0	0
ADORA2B mediated anti-inflammatory cytokines production	R-HSA-9660821	9.330533e-01	0.030	0	0
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	9.332122e-01	0.030	0	0
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	9.332122e-01	0.030	0	0
Glutamate Neurotransmitter Release Cycle	R-HSA-210500	9.344014e-01	0.029	0	0
Suppression of phagosomal maturation	R-HSA-9637687	9.344014e-01	0.029	0	0
Regulation of TP53 Degradation	R-HSA-6804757	9.348653e-01	0.029	0	0
Triglyceride catabolism	R-HSA-163560	9.348653e-01	0.029	0	0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	R-HSA-399955	9.365638e-01	0.028	0	0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	R-HSA-9634600	9.365638e-01	0.028	0	0
Mineralocorticoid biosynthesis	R-HSA-193993	9.365638e-01	0.028	0	0
Attachment and Entry	R-HSA-9678110	9.365638e-01	0.028	0	0
Formation of TC-NER Pre-Incision Complex	R-HSA-6781823	9.388280e-01	0.027	0	0
Formation of the ternary complex, and subsequently, the 43S complex	R-HSA-72695	9.388280e-01	0.027	0	0
Developmental Biology	R-HSA-1266738	9.390933e-01	0.027	1	0
GTP hydrolysis and joining of the 60S ribosomal subunit	R-HSA-72706	9.398089e-01	0.027	0	0
L13a-mediated translational silencing of Ceruloplasmin expression	R-HSA-156827	9.398089e-01	0.027	0	0
Eukaryotic Translation Elongation	R-HSA-156842	9.401883e-01	0.027	0	0
Signaling by Insulin receptor	R-HSA-74752	9.401883e-01	0.027	0	0
Degradation of AXIN	R-HSA-4641257	9.410305e-01	0.026	0	0
SIRT1 negatively regulates rRNA expression	R-HSA-427359	9.410305e-01	0.026	0	0
Metabolism of folate and pterines	R-HSA-196757	9.410305e-01	0.026	0	0
Meiosis	R-HSA-1500620	9.410660e-01	0.026	0	0
Tat-mediated HIV elongation arrest and recovery	R-HSA-167243	9.414026e-01	0.026	0	0
Pausing and recovery of Tat-mediated HIV elongation	R-HSA-167238	9.414026e-01	0.026	0	0
Cristae formation	R-HSA-8949613	9.414026e-01	0.026	0	0
RNA Polymerase I Promoter Opening	R-HSA-73728	9.414026e-01	0.026	0	0
Signaling by BMP	R-HSA-201451	9.414026e-01	0.026	0	0
Synthesis of PE	R-HSA-1483213	9.414026e-01	0.026	0	0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	R-HSA-193807	9.414026e-01	0.026	0	0
Cap-dependent Translation Initiation	R-HSA-72737	9.436773e-01	0.025	0	0
Eukaryotic Translation Initiation	R-HSA-72613	9.436773e-01	0.025	0	0
TAK1-dependent IKK and NF-kappa-B activation	R-HSA-445989	9.441457e-01	0.025	0	0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	R-HSA-2892247	9.447395e-01	0.025	0	0
G beta:gamma signalling through CDC42	R-HSA-8964616	9.447395e-01	0.025	0	0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	R-HSA-975110	9.447395e-01	0.025	0	0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	R-HSA-77288	9.447395e-01	0.025	0	0
STAT5 activation downstream of FLT3 ITD mutants	R-HSA-9702518	9.447395e-01	0.025	0	0
Regulation of innate immune responses to cytosolic DNA	R-HSA-3134975	9.447395e-01	0.025	0	0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	R-HSA-77346	9.447395e-01	0.025	0	0
Synthesis of PG	R-HSA-1483148	9.447395e-01	0.025	0	0
Coenzyme A biosynthesis	R-HSA-196783	9.447395e-01	0.025	0	0
Acetylcholine regulates insulin secretion	R-HSA-399997	9.447395e-01	0.025	0	0
tRNA modification in the mitochondrion	R-HSA-6787450	9.447395e-01	0.025	0	0
G-protein mediated events	R-HSA-112040	9.449707e-01	0.025	0	0
RIPK1-mediated regulated necrosis	R-HSA-5213460	9.466509e-01	0.024	0	0
Biofilm formation	R-HSA-9931953	9.466509e-01	0.024	0	0
SLC-mediated transport of inorganic anions	R-HSA-9958790	9.466509e-01	0.024	0	0
HCMV Late Events	R-HSA-9610379	9.471335e-01	0.024	0	0
HIV elongation arrest and recovery	R-HSA-167287	9.476894e-01	0.023	0	0
Pausing and recovery of HIV elongation	R-HSA-167290	9.476894e-01	0.023	0	0
FRS-mediated FGFR2 signaling	R-HSA-5654700	9.476894e-01	0.023	0	0
Negative regulation of FGFR3 signaling	R-HSA-5654732	9.476894e-01	0.023	0	0
Activation of kainate receptors upon glutamate binding	R-HSA-451326	9.476894e-01	0.023	0	0
ATF4 activates genes in response to endoplasmic reticulum stress	R-HSA-380994	9.476894e-01	0.023	0	0
Pyroptosis	R-HSA-5620971	9.476894e-01	0.023	0	0
Integrin cell surface interactions	R-HSA-216083	9.506607e-01	0.022	0	0
Respiratory syncytial virus (RSV) genome replication, transcription and translation	R-HSA-9820965	9.517694e-01	0.021	0	0
Regulation of FZD by ubiquitination	R-HSA-4641263	9.518619e-01	0.021	0	0
Sulfide oxidation to sulfate	R-HSA-1614517	9.518619e-01	0.021	0	0
Elevation of cytosolic Ca2+ levels	R-HSA-139853	9.518619e-01	0.021	0	0
Catecholamine biosynthesis	R-HSA-209905	9.518619e-01	0.021	0	0
Modulation of host responses by IFN-stimulated genes	R-HSA-9909505	9.518619e-01	0.021	0	0
Glycogen storage diseases	R-HSA-3229121	9.518619e-01	0.021	0	0
Chaperonin-mediated protein folding	R-HSA-390466	9.525506e-01	0.021	0	0
Developmental Lineage of Pancreatic Ductal Cells	R-HSA-9925563	9.531378e-01	0.021	0	0
Developmental Lineage of Mammary Gland Myoepithelial Cells	R-HSA-9927432	9.533295e-01	0.021	0	0
Activation of Matrix Metalloproteinases	R-HSA-1592389	9.533295e-01	0.021	0	0
Negative regulation of FGFR4 signaling	R-HSA-5654733	9.533295e-01	0.021	0	0
DARPP-32 events	R-HSA-180024	9.533295e-01	0.021	1	1
Signaling by CSF3 (G-CSF)	R-HSA-9674555	9.533295e-01	0.021	0	0
Degradation of CDH1	R-HSA-9766229	9.535333e-01	0.021	0	0
Peptide chain elongation	R-HSA-156902	9.559096e-01	0.020	0	0
Interleukin-1 family signaling	R-HSA-446652	9.570808e-01	0.019	0	0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	R-HSA-9856530	9.576995e-01	0.019	0	0
GAB1 signalosome	R-HSA-180292	9.580667e-01	0.019	0	0
Trafficking of GluR2-containing AMPA receptors	R-HSA-416993	9.580667e-01	0.019	0	0
Cytosolic iron-sulfur cluster assembly	R-HSA-2564830	9.580667e-01	0.019	0	0
Organic anion transport by SLC5/17/25 transporters	R-HSA-428643	9.580667e-01	0.019	0	0
Nucleotide-like (purinergic) receptors	R-HSA-418038	9.580667e-01	0.019	0	0
DAP12 signaling	R-HSA-2424491	9.583851e-01	0.018	0	0
ECM proteoglycans	R-HSA-3000178	9.601936e-01	0.018	0	0
HCMV Early Events	R-HSA-9609690	9.603664e-01	0.018	0	0
Major pathway of rRNA processing in the nucleolus and cytosol	R-HSA-6791226	9.604614e-01	0.018	0	0
Influenza Infection	R-HSA-168255	9.610555e-01	0.017	0	0
Hedgehog ligand biogenesis	R-HSA-5358346	9.614474e-01	0.017	0	0
Molecules associated with elastic fibres	R-HSA-2129379	9.629133e-01	0.016	0	0
Pre-NOTCH Processing in Golgi	R-HSA-1912420	9.634720e-01	0.016	0	0
Abortive elongation of HIV-1 transcript in the absence of Tat	R-HSA-167242	9.634720e-01	0.016	0	0
mRNA decay by 3' to 5' exoribonuclease	R-HSA-429958	9.634720e-01	0.016	0	0
Specification of the neural plate border	R-HSA-9834899	9.634720e-01	0.016	0	0
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	9.634720e-01	0.016	0	0
Diseases of hemostasis	R-HSA-9671793	9.634720e-01	0.016	0	0
Other interleukin signaling	R-HSA-449836	9.634720e-01	0.016	0	0
Methionine salvage pathway	R-HSA-1237112	9.634720e-01	0.016	0	0
HDL remodeling	R-HSA-8964058	9.634720e-01	0.016	0	0
Strand-asynchronous mitochondrial DNA replication	R-HSA-9913635	9.634720e-01	0.016	0	0
The NLRP3 inflammasome	R-HSA-844456	9.634720e-01	0.016	0	0
Reproduction	R-HSA-1474165	9.636516e-01	0.016	0	0
Degradation of CRY and PER proteins	R-HSA-9932298	9.645032e-01	0.016	0	0
Intra-Golgi traffic	R-HSA-6811438	9.645032e-01	0.016	0	0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	R-HSA-9954714	9.647458e-01	0.016	0	0
SRP-dependent cotranslational protein targeting to membrane	R-HSA-1799339	9.649713e-01	0.015	0	0
Translocation of SLC2A4 (GLUT4) to the plasma membrane	R-HSA-1445148	9.662692e-01	0.015	0	0
HCMV Infection	R-HSA-9609646	9.669146e-01	0.015	0	0
Interferon Signaling	R-HSA-913531	9.672516e-01	0.014	0	0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	R-HSA-975956	9.673144e-01	0.014	0	0
Toll-like Receptor Cascades	R-HSA-168898	9.674132e-01	0.014	0	0
Activation of GABAB receptors	R-HSA-991365	9.679912e-01	0.014	0	0
GABA B receptor activation	R-HSA-977444	9.679912e-01	0.014	0	0
Incretin synthesis, secretion, and inactivation	R-HSA-400508	9.679912e-01	0.014	0	0
Formation of ATP by chemiosmotic coupling	R-HSA-163210	9.681809e-01	0.014	0	0
Acyl chain remodelling of PI	R-HSA-1482922	9.681809e-01	0.014	0	0
Wax and plasmalogen biosynthesis	R-HSA-8848584	9.681809e-01	0.014	0	0
Creatine metabolism	R-HSA-71288	9.681809e-01	0.014	0	0
Glycogen synthesis	R-HSA-3322077	9.681809e-01	0.014	0	0
Protein hydroxylation	R-HSA-9629569	9.681809e-01	0.014	0	0
Protein folding	R-HSA-391251	9.697122e-01	0.013	0	0
Signaling by VEGF	R-HSA-194138	9.703386e-01	0.013	0	0
Negative regulation of FGFR1 signaling	R-HSA-5654726	9.705902e-01	0.013	0	0
Recycling of bile acids and salts	R-HSA-159418	9.705902e-01	0.013	0	0
MAPK1/MAPK3 signaling	R-HSA-5684996	9.720784e-01	0.012	0	0
MyD88 deficiency (TLR2/4)	R-HSA-5602498	9.722829e-01	0.012	0	0
PD-L1(CD274) glycosylation and translocation to plasma membrane	R-HSA-9931295	9.722829e-01	0.012	0	0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane	R-HSA-9768727	9.738294e-01	0.012	0	0
Heme degradation	R-HSA-189483	9.738294e-01	0.012	0	0
Vitamin B5 (pantothenate) metabolism	R-HSA-199220	9.738294e-01	0.012	0	0
RAF/MAP kinase cascade	R-HSA-5673001	9.739275e-01	0.011	0	0
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	9.740338e-01	0.011	0	0
Neddylation	R-HSA-8951664	9.748701e-01	0.011	0	0
IRAK4 deficiency (TLR2/4)	R-HSA-5603041	9.758563e-01	0.011	0	0
Molybdenum cofactor biosynthesis	R-HSA-947581	9.758563e-01	0.011	0	0
Androgen biosynthesis	R-HSA-193048	9.758563e-01	0.011	0	0
Metabolism of Angiotensinogen to Angiotensins	R-HSA-2022377	9.758563e-01	0.011	0	0
Attachment and Entry	R-HSA-9694614	9.758563e-01	0.011	0	0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	R-HSA-9954716	9.759761e-01	0.011	0	0
Asymmetric localization of PCP proteins	R-HSA-4608870	9.766114e-01	0.010	0	0
Defective CFTR causes cystic fibrosis	R-HSA-5678895	9.766114e-01	0.010	0	0
Autodegradation of the E3 ubiquitin ligase COP1	R-HSA-349425	9.767224e-01	0.010	0	0
Negative regulation of FGFR2 signaling	R-HSA-5654727	9.767224e-01	0.010	0	0
Formation of a pool of free 40S subunits	R-HSA-72689	9.777844e-01	0.010	0	0
RSV-host interactions	R-HSA-9833110	9.781770e-01	0.010	0	0
Regulation of CDH1 Function	R-HSA-9764561	9.783051e-01	0.010	0	0
Respiratory Syncytial Virus Infection Pathway	R-HSA-9820952	9.783739e-01	0.009	0	0
Regulated Necrosis	R-HSA-5218859	9.787406e-01	0.009	0	0
Regulation of IFNA/IFNB signaling	R-HSA-912694	9.789693e-01	0.009	0	0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	R-HSA-9670439	9.789693e-01	0.009	0	0
Reactions specific to the complex N-glycan synthesis pathway	R-HSA-975578	9.789693e-01	0.009	0	0
Signaling by KIT in disease	R-HSA-9669938	9.789693e-01	0.009	0	0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	R-HSA-9857377	9.789693e-01	0.009	0	0
LDL clearance	R-HSA-8964038	9.789693e-01	0.009	0	0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	R-HSA-8854050	9.793047e-01	0.009	0	0
Metabolism of ingested SeMet, Sec, MeSec into H2Se	R-HSA-2408508	9.793047e-01	0.009	0	0
PERK regulates gene expression	R-HSA-381042	9.793047e-01	0.009	0	0
Signaling by Hedgehog	R-HSA-5358351	9.797716e-01	0.009	0	0
Synthesis of PC	R-HSA-1483191	9.810772e-01	0.008	0	0
Signaling by FGFR2	R-HSA-5654738	9.814417e-01	0.008	0	0
PKR-mediated signaling	R-HSA-9833482	9.814417e-01	0.008	0	0
AUF1 (hnRNP D0) binds and destabilizes mRNA	R-HSA-450408	9.816083e-01	0.008	0	0
Lysosome Vesicle Biogenesis	R-HSA-432720	9.816083e-01	0.008	0	0
GPVI-mediated activation cascade	R-HSA-114604	9.816083e-01	0.008	0	0
TP53 Regulates Metabolic Genes	R-HSA-5628897	9.816627e-01	0.008	0	0
Free fatty acids regulate insulin secretion	R-HSA-400451	9.816810e-01	0.008	0	0
Peroxisomal protein import	R-HSA-9033241	9.821696e-01	0.008	0	0
Degradation of the extracellular matrix	R-HSA-1474228	9.828129e-01	0.008	0	0
VEGFA-VEGFR2 Pathway	R-HSA-4420097	9.829745e-01	0.007	0	0
Metal ion SLC transporters	R-HSA-425410	9.829924e-01	0.007	0	0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	R-HSA-9762114	9.836621e-01	0.007	0	0
Degradation of DVL	R-HSA-4641258	9.836621e-01	0.007	0	0
Sphingolipid de novo biosynthesis	R-HSA-1660661	9.838482e-01	0.007	0	0
Hedgehog 'on' state	R-HSA-5632684	9.838780e-01	0.007	0	0
TRAF6 mediated NF-kB activation	R-HSA-933542	9.840432e-01	0.007	0	0
Thromboxane signalling through TP receptor	R-HSA-428930	9.840432e-01	0.007	0	0
Potential therapeutics for SARS	R-HSA-9679191	9.841916e-01	0.007	0	0
Gap junction trafficking and regulation	R-HSA-157858	9.847212e-01	0.007	0	0
Developmental Lineages of the Mammary Gland	R-HSA-9924644	9.853131e-01	0.006	0	0
Regulation of mRNA stability by proteins that bind AU-rich elements	R-HSA-450531	9.853131e-01	0.006	0	0
trans-Golgi Network Vesicle Budding	R-HSA-199992	9.853131e-01	0.006	0	0
Transcriptional regulation of pluripotent stem cells	R-HSA-452723	9.854922e-01	0.006	0	0
Elastic fibre formation	R-HSA-1566948	9.854922e-01	0.006	0	0
Cytokine Signaling in Immune system	R-HSA-1280215	9.856885e-01	0.006	0	0
Tight junction interactions	R-HSA-420029	9.861009e-01	0.006	0	0
VEGFR2 mediated cell proliferation	R-HSA-5218921	9.861009e-01	0.006	0	0
Fertilization	R-HSA-1187000	9.861009e-01	0.006	0	0
Regulation of expression of SLITs and ROBOs	R-HSA-9010553	9.861773e-01	0.006	0	0
rRNA processing in the nucleus and cytosol	R-HSA-8868773	9.862325e-01	0.006	0	0
Extra-nuclear estrogen signaling	R-HSA-9009391	9.862489e-01	0.006	0	0
Regulation of RAS by GAPs	R-HSA-5658442	9.862808e-01	0.006	0	0
Signaling by FGFR2 in disease	R-HSA-5655253	9.862808e-01	0.006	0	0
tRNA processing	R-HSA-72306	9.865324e-01	0.006	0	0
Cellular response to chemical stress	R-HSA-9711123	9.867600e-01	0.006	0	0
Plasma lipoprotein clearance	R-HSA-8964043	9.871221e-01	0.006	0	0
Adrenaline,noradrenaline inhibits insulin secretion	R-HSA-400042	9.878933e-01	0.005	0	0
Sphingolipid catabolism	R-HSA-9845614	9.878933e-01	0.005	0	0
Integration of energy metabolism	R-HSA-163685	9.879445e-01	0.005	0	0
Complex I biogenesis	R-HSA-6799198	9.880297e-01	0.005	0	0
Regulation of PD-L1(CD274) Post-translational modification	R-HSA-9909615	9.891009e-01	0.005	0	0
Cargo recognition for clathrin-mediated endocytosis	R-HSA-8856825	9.892485e-01	0.005	0	0
CD28 dependent PI3K/Akt signaling	R-HSA-389357	9.894547e-01	0.005	0	0
ER Quality Control Compartment (ERQC)	R-HSA-901032	9.894547e-01	0.005	0	0
Insulin processing	R-HSA-264876	9.894547e-01	0.005	0	0
Ribosome-associated quality control	R-HSA-9948299	9.895678e-01	0.005	0	0
Hh mutants are degraded by ERAD	R-HSA-5362768	9.898640e-01	0.004	0	0
VEGFR2 mediated vascular permeability	R-HSA-5218920	9.898640e-01	0.004	0	0
Amino acids regulate mTORC1	R-HSA-9639288	9.900947e-01	0.004	0	0
Regulation of PTEN stability and activity	R-HSA-8948751	9.900947e-01	0.004	0	0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	R-HSA-8950505	9.902202e-01	0.004	0	0
Unfolded Protein Response (UPR)	R-HSA-381119	9.903012e-01	0.004	0	0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide	R-HSA-9954709	9.903964e-01	0.004	0	0
Eukaryotic Translation Termination	R-HSA-72764	9.903964e-01	0.004	0	0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	R-HSA-6811558	9.907422e-01	0.004	0	0
SARS-CoV Infections	R-HSA-9679506	9.907506e-01	0.004	0	0
Insulin receptor recycling	R-HSA-77387	9.908148e-01	0.004	0	0
Inflammasomes	R-HSA-622312	9.908148e-01	0.004	0	0
Cellular response to starvation	R-HSA-9711097	9.908412e-01	0.004	0	0
Degradation of GLI2 by the proteasome	R-HSA-5610783	9.910121e-01	0.004	0	0
SLC-mediated transport of neurotransmitters	R-HSA-442660	9.910121e-01	0.004	0	0
Heme biosynthesis	R-HSA-189451	9.910121e-01	0.004	0	0
Scavenging by Class A Receptors	R-HSA-3000480	9.910121e-01	0.004	0	0
Translation of Structural Proteins	R-HSA-9683701	9.910121e-01	0.004	0	0
Thyroxine biosynthesis	R-HSA-209968	9.919996e-01	0.003	0	0
Platelet calcium homeostasis	R-HSA-418360	9.919996e-01	0.003	0	0
Phospholipid metabolism	R-HSA-1483257	9.920197e-01	0.003	0	0
G alpha (z) signalling events	R-HSA-418597	9.920451e-01	0.003	0	0
Regulation of insulin secretion	R-HSA-422356	9.926108e-01	0.003	0	0
Ion homeostasis	R-HSA-5578775	9.928755e-01	0.003	0	0
Developmental Cell Lineages of the Integumentary System	R-HSA-9734779	9.929268e-01	0.003	0	0
Hh mutants abrogate ligand secretion	R-HSA-5387390	9.929398e-01	0.003	0	0
Neurotransmitter clearance	R-HSA-112311	9.930316e-01	0.003	0	0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	R-HSA-1474151	9.930316e-01	0.003	0	0
DAP12 interactions	R-HSA-2172127	9.937454e-01	0.003	0	0
Gap junction trafficking	R-HSA-190828	9.937454e-01	0.003	0	0
Amyloid fiber formation	R-HSA-977225	9.937865e-01	0.003	0	0
Hedgehog 'off' state	R-HSA-5610787	9.938085e-01	0.003	0	0
Respiratory syncytial virus (RSV) attachment and entry	R-HSA-9820960	9.939305e-01	0.003	0	0
Regulation of activated PAK-2p34 by proteasome mediated degradation	R-HSA-211733	9.939305e-01	0.003	0	0
Fatty acyl-CoA biosynthesis	R-HSA-75105	9.941448e-01	0.003	0	0
Regulation of T cell activation by CD28 family	R-HSA-388841	9.942582e-01	0.003	0	0
Interleukin-1 signaling	R-HSA-9020702	9.943359e-01	0.002	0	0
Selenocysteine synthesis	R-HSA-2408557	9.943359e-01	0.002	0	0
Transport to the Golgi and subsequent modification	R-HSA-948021	9.943832e-01	0.002	0	0
Somitogenesis	R-HSA-9824272	9.944608e-01	0.002	0	0
Degradation of cysteine and homocysteine	R-HSA-1614558	9.944608e-01	0.002	0	0
Diseases associated with glycosaminoglycan metabolism	R-HSA-3560782	9.944608e-01	0.002	0	0
Regulation of ornithine decarboxylase (ODC)	R-HSA-350562	9.947135e-01	0.002	0	0
DAG1 glycosylations	R-HSA-8931838	9.947135e-01	0.002	0	0
Metabolism of porphyrins	R-HSA-189445	9.947223e-01	0.002	0	0
TNFR2 non-canonical NF-kB pathway	R-HSA-5668541	9.948921e-01	0.002	0	0
Amino acid transport across the plasma membrane	R-HSA-352230	9.948937e-01	0.002	0	0
Triglyceride metabolism	R-HSA-8979227	9.948937e-01	0.002	0	0
Negative regulation of the PI3K/AKT network	R-HSA-199418	9.950934e-01	0.002	0	0
Viral mRNA Translation	R-HSA-192823	9.952655e-01	0.002	0	0
G-protein beta:gamma signalling	R-HSA-397795	9.953956e-01	0.002	0	0
RAB geranylgeranylation	R-HSA-8873719	9.954336e-01	0.002	0	0
GABA receptor activation	R-HSA-977443	9.954336e-01	0.002	0	0
Opioid Signalling	R-HSA-111885	9.956739e-01	0.002	1	0
Nucleotide salvage	R-HSA-8956321	9.959179e-01	0.002	0	0
Striated Muscle Contraction	R-HSA-390522	9.959896e-01	0.002	0	0
Acyl chain remodelling of PC	R-HSA-1482788	9.959896e-01	0.002	0	0
Vpu mediated degradation of CD4	R-HSA-180534	9.959896e-01	0.002	0	0
DDX58/IFIH1-mediated induction of interferon-alpha/beta	R-HSA-168928	9.960602e-01	0.002	0	0
Vesicle-mediated transport	R-HSA-5653656	9.960811e-01	0.002	0	0
ROS and RNS production in phagocytes	R-HSA-1222556	9.961439e-01	0.002	0	0
Intraflagellar transport	R-HSA-5620924	9.961587e-01	0.002	0	0
Plasma lipoprotein remodeling	R-HSA-8963899	9.961587e-01	0.002	0	0
eNOS activation	R-HSA-203615	9.965071e-01	0.002	0	0
Ubiquitin-dependent degradation of Cyclin D	R-HSA-75815	9.965071e-01	0.002	0	0
Regulation of TLR by endogenous ligand	R-HSA-5686938	9.965071e-01	0.002	0	0
Calnexin/calreticulin cycle	R-HSA-901042	9.965071e-01	0.002	0	0
Hyaluronan metabolism	R-HSA-2142845	9.965071e-01	0.002	0	0
Signal amplification	R-HSA-392518	9.965071e-01	0.002	0	0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	R-HSA-532668	9.966017e-01	0.001	0	0
Interleukin-12 signaling	R-HSA-9020591	9.968777e-01	0.001	0	0
Interleukin-12 family signaling	R-HSA-447115	9.968917e-01	0.001	0	0
Acyl chain remodelling of PE	R-HSA-1482839	9.969578e-01	0.001	0	0
Regulation of Apoptosis	R-HSA-169911	9.969578e-01	0.001	0	0
Signaling by FGFR	R-HSA-190236	9.973108e-01	0.001	0	0
Meiotic recombination	R-HSA-912446	9.973423e-01	0.001	0	0
Vif-mediated degradation of APOBEC3G	R-HSA-180585	9.973504e-01	0.001	0	0
Beta-catenin independent WNT signaling	R-HSA-3858494	9.974596e-01	0.001	0	0
SLC-mediated transport of organic anions	R-HSA-9955298	9.974755e-01	0.001	0	0
Interleukin-10 signaling	R-HSA-6783783	9.974755e-01	0.001	0	0
tRNA modification in the nucleus and cytosol	R-HSA-6782315	9.976811e-01	0.001	0	0
Beta-oxidation of very long chain fatty acids	R-HSA-390247	9.976923e-01	0.001	0	0
SLC-mediated transport of organic cations	R-HSA-549127	9.976923e-01	0.001	0	0
Neurotransmitter release cycle	R-HSA-112310	9.977030e-01	0.001	0	0
SLC-mediated transport of amino acids	R-HSA-9958863	9.979310e-01	0.001	0	0
tRNA processing in the mitochondrion	R-HSA-6785470	9.979902e-01	0.001	0	0
Purine salvage	R-HSA-74217	9.979902e-01	0.001	0	0
Interferon gamma signaling	R-HSA-877300	9.980669e-01	0.001	0	0
GSK3B-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929356	9.982496e-01	0.001	0	0
Cross-presentation of soluble exogenous antigens (endosomes)	R-HSA-1236978	9.982496e-01	0.001	0	0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	R-HSA-381771	9.982496e-01	0.001	0	0
Plasma lipoprotein assembly, remodeling, and clearance	R-HSA-174824	9.983078e-01	0.001	0	0
Late SARS-CoV-2 Infection Events	R-HSA-9772573	9.983078e-01	0.001	0	0
Regulation of actin dynamics for phagocytic cup formation	R-HSA-2029482	9.983348e-01	0.001	0	0
Paracetamol ADME	R-HSA-9753281	9.983790e-01	0.001	0	0
Diseases associated with the TLR signaling cascade	R-HSA-5602358	9.984755e-01	0.001	0	0
Diseases of Immune System	R-HSA-5260271	9.984755e-01	0.001	0	0
Negative regulation of NOTCH4 signaling	R-HSA-9604323	9.984755e-01	0.001	0	0
rRNA processing in the mitochondrion	R-HSA-8868766	9.984755e-01	0.001	0	0
Glycogen metabolism	R-HSA-8982491	9.984755e-01	0.001	0	0
N-glycan antennae elongation in the medial/trans-Golgi	R-HSA-975576	9.984755e-01	0.001	0	0
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	9.985331e-01	0.001	0	0
Metabolism of amine-derived hormones	R-HSA-209776	9.985683e-01	0.001	0	0
Detoxification of Reactive Oxygen Species	R-HSA-3299685	9.985683e-01	0.001	0	0
Mitochondrial protein degradation	R-HSA-9837999	9.986220e-01	0.001	0	0
SPOP-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929491	9.986723e-01	0.001	0	0
NIK-->noncanonical NF-kB signaling	R-HSA-5676590	9.986723e-01	0.001	0	0
Maturation of spike protein	R-HSA-9694548	9.986723e-01	0.001	0	0
Purine ribonucleoside monophosphate biosynthesis	R-HSA-73817	9.986723e-01	0.001	0	0
Retinoid metabolism and transport	R-HSA-975634	9.986927e-01	0.001	0	0
Selenoamino acid metabolism	R-HSA-2408522	9.987109e-01	0.001	0	0
rRNA processing	R-HSA-72312	9.987125e-01	0.001	0	0
Synthesis of PA	R-HSA-1483166	9.987357e-01	0.001	0	0
Interferon alpha/beta signaling	R-HSA-909733	9.988220e-01	0.001	0	0
Degradation of GLI1 by the proteasome	R-HSA-5610780	9.988437e-01	0.001	0	0
GLI3 is processed to GLI3R by the proteasome	R-HSA-5610785	9.988437e-01	0.001	0	0
CLEC7A (Dectin-1) signaling	R-HSA-5607764	9.989897e-01	0.000	0	0
Potassium Channels	R-HSA-1296071	9.989897e-01	0.000	0	0
SLC transporter disorders	R-HSA-5619102	9.989927e-01	0.000	0	0
Cytosolic tRNA aminoacylation	R-HSA-379716	9.989930e-01	0.000	0	0
Sulfur amino acid metabolism	R-HSA-1614635	9.990453e-01	0.000	0	0
Synthesis of very long-chain fatty acyl-CoAs	R-HSA-75876	9.991230e-01	0.000	0	0
Ion channel transport	R-HSA-983712	9.991659e-01	0.000	0	0
Endogenous sterols	R-HSA-211976	9.992327e-01	0.000	0	0
Proteasome assembly	R-HSA-9907900	9.992362e-01	0.000	0	0
Methylation	R-HSA-156581	9.992362e-01	0.000	0	0
Cobalamin (Cbl, vitamin B12) transport and metabolism	R-HSA-196741	9.992362e-01	0.000	0	0
Synthesis of Leukotrienes (LT) and Eoxins (EX)	R-HSA-2142691	9.992362e-01	0.000	0	0
Surfactant metabolism	R-HSA-5683826	9.992362e-01	0.000	0	0
Parasite infection	R-HSA-9664407	9.992984e-01	0.000	0	0
Leishmania phagocytosis	R-HSA-9664417	9.992984e-01	0.000	0	0
FCGR3A-mediated phagocytosis	R-HSA-9664422	9.992984e-01	0.000	0	0
The role of GTSE1 in G2/M progression after G2 checkpoint	R-HSA-8852276	9.993231e-01	0.000	0	0
Mitochondrial protein import	R-HSA-1268020	9.993231e-01	0.000	0	0
mitochondrial fatty acid beta-oxidation of saturated fatty acids	R-HSA-77286	9.993348e-01	0.000	0	0
Dectin-1 mediated noncanonical NF-kB signaling	R-HSA-5607761	9.993348e-01	0.000	0	0
p53-Independent G1/S DNA Damage Checkpoint	R-HSA-69613	9.993348e-01	0.000	0	0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A	R-HSA-69601	9.993348e-01	0.000	0	0
ABC-family proteins mediated transport	R-HSA-382556	9.993349e-01	0.000	0	0
G alpha (s) signalling events	R-HSA-418555	9.993360e-01	0.000	0	0
Translation of Structural Proteins	R-HSA-9694635	9.993487e-01	0.000	0	0
Neurotransmitter receptors and postsynaptic signal transmission	R-HSA-112314	9.993733e-01	0.000	0	0
Glycerophospholipid biosynthesis	R-HSA-1483206	9.993814e-01	0.000	0	0
PCP/CE pathway	R-HSA-4086400	9.994206e-01	0.000	0	0
ABC transporter disorders	R-HSA-5619084	9.994206e-01	0.000	0	0
Regulation of pyruvate metabolism	R-HSA-9861718	9.994207e-01	0.000	0	0
Inactivation, recovery and regulation of the phototransduction cascade	R-HSA-2514859	9.994207e-01	0.000	0	0
Purinergic signaling in leishmaniasis infection	R-HSA-9660826	9.994207e-01	0.000	0	0
Cell recruitment (pro-inflammatory response)	R-HSA-9664424	9.994207e-01	0.000	0	0
Ion transport by P-type ATPases	R-HSA-936837	9.994734e-01	0.000	0	0
Fcgamma receptor (FCGR) dependent phagocytosis	R-HSA-2029480	9.994846e-01	0.000	0	0
Carboxyterminal post-translational modifications of tubulin	R-HSA-8955332	9.994955e-01	0.000	0	0
Co-stimulation by CD28	R-HSA-389356	9.995607e-01	0.000	0	0
Gluconeogenesis	R-HSA-70263	9.995607e-01	0.000	0	0
Metabolism of fat-soluble vitamins	R-HSA-6806667	9.995926e-01	0.000	0	0
Nicotinate metabolism	R-HSA-196807	9.996391e-01	0.000	0	0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	R-HSA-193368	9.996391e-01	0.000	0	0
Platelet degranulation	R-HSA-114608	9.996670e-01	0.000	0	0
Peptide hormone metabolism	R-HSA-2980736	9.997003e-01	0.000	0	0
Complex IV assembly	R-HSA-9864848	9.997099e-01	0.000	0	0
Activation of NF-kappaB in B cells	R-HSA-1169091	9.997099e-01	0.000	0	0
The phototransduction cascade	R-HSA-2514856	9.997099e-01	0.000	0	0
Platelet activation, signaling and aggregation	R-HSA-76002	9.997454e-01	0.000	0	0
Nucleotide biosynthesis	R-HSA-8956320	9.997800e-01	0.000	0	0
Diseases associated with O-glycosylation of proteins	R-HSA-3906995	9.997825e-01	0.000	0	0
Metabolism of cofactors	R-HSA-8978934	9.997825e-01	0.000	0	0
Cardiac conduction	R-HSA-5576891	9.997977e-01	0.000	0	0
Post-translational protein phosphorylation	R-HSA-8957275	9.997989e-01	0.000	0	0
Interconversion of nucleotide di- and triphosphates	R-HSA-499943	9.998084e-01	0.000	0	0
Synthesis of bile acids and bile salts	R-HSA-192105	9.998204e-01	0.000	0	0
Chondroitin sulfate/dermatan sulfate metabolism	R-HSA-1793185	9.998332e-01	0.000	0	0
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	9.998346e-01	0.000	0	0
Extracellular matrix organization	R-HSA-1474244	9.998555e-01	0.000	0	0
ER-Phagosome pathway	R-HSA-1236974	9.998601e-01	0.000	0	0
Iron uptake and transport	R-HSA-917937	9.998692e-01	0.000	0	0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	R-HSA-381426	9.998803e-01	0.000	0	0
Adaptive Immune System	R-HSA-1280218	9.998959e-01	0.000	0	0
FCERI mediated Ca+2 mobilization	R-HSA-2871809	9.999038e-01	0.000	0	0
Cholesterol biosynthesis	R-HSA-191273	9.999108e-01	0.000	0	0
tRNA Aminoacylation	R-HSA-379724	9.999165e-01	0.000	0	0
Metabolism of polyamines	R-HSA-351202	9.999165e-01	0.000	0	0
Developmental Lineage of Pancreatic Acinar Cells	R-HSA-9925561	9.999215e-01	0.000	0	0
Metabolic disorders of biological oxidation enzymes	R-HSA-5579029	9.999215e-01	0.000	0	0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	R-HSA-983695	9.999232e-01	0.000	0	0
Platelet homeostasis	R-HSA-418346	9.999279e-01	0.000	0	0
Developmental Cell Lineages of the Exocrine Pancreas	R-HSA-9820448	9.999326e-01	0.000	0	0
Protein localization	R-HSA-9609507	9.999390e-01	0.000	0	0
Mitochondrial translation termination	R-HSA-5419276	9.999489e-01	0.000	0	0
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	9.999526e-01	0.000	0	0
Mitochondrial translation elongation	R-HSA-5389840	9.999526e-01	0.000	0	0
Bile acid and bile salt metabolism	R-HSA-194068	9.999545e-01	0.000	0	0
Muscle contraction	R-HSA-397014	9.999559e-01	0.000	0	0
Peroxisomal lipid metabolism	R-HSA-390918	9.999586e-01	0.000	0	0
Mitochondrial translation initiation	R-HSA-5368286	9.999629e-01	0.000	0	0
Metabolism of steroid hormones	R-HSA-196071	9.999683e-01	0.000	0	0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	R-HSA-163841	9.999719e-01	0.000	0	0
FCGR3A-mediated IL10 synthesis	R-HSA-9664323	9.999746e-01	0.000	0	0
Pyruvate metabolism	R-HSA-70268	9.999753e-01	0.000	0	0
Downstream TCR signaling	R-HSA-202424	9.999832e-01	0.000	0	0
Purine catabolism	R-HSA-74259	9.999841e-01	0.000	0	0
Disorders of transmembrane transporters	R-HSA-5619115	9.999860e-01	0.000	0	0
Diseases of carbohydrate metabolism	R-HSA-5663084	9.999862e-01	0.000	0	0
Citric acid cycle (TCA cycle)	R-HSA-71403	9.999895e-01	0.000	0	0
Infection with Mycobacterium tuberculosis	R-HSA-9635486	9.999900e-01	0.000	0	0
Antigen processing-Cross presentation	R-HSA-1236975	9.999903e-01	0.000	0	0
C-type lectin receptors (CLRs)	R-HSA-5621481	9.999912e-01	0.000	0	0
Viral Infection Pathways	R-HSA-9824446	9.999921e-01	0.000	0	0
Mitochondrial Fatty Acid Beta-Oxidation	R-HSA-77289	9.999923e-01	0.000	0	0
Formation of the cornified envelope	R-HSA-6809371	9.999930e-01	0.000	0	0
FCERI mediated MAPK activation	R-HSA-2871796	9.999941e-01	0.000	0	0
Transmission across Chemical Synapses	R-HSA-112315	9.999946e-01	0.000	0	0
Neuronal System	R-HSA-112316	9.999959e-01	0.000	0	0
Developmental Cell Lineages	R-HSA-9734767	9.999967e-01	0.000	0	0
Mitochondrial ribosome-associated quality control	R-HSA-9937383	9.999976e-01	0.000	0	0
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	9.999977e-01	0.000	0	0
Metabolism of steroids	R-HSA-8957322	9.999980e-01	0.000	0	0
Leishmania infection	R-HSA-9658195	9.999982e-01	0.000	0	0
Parasitic Infection Pathways	R-HSA-9824443	9.999982e-01	0.000	0	0
Class B/2 (Secretin family receptors)	R-HSA-373080	9.999989e-01	0.000	0	0
Mitochondrial translation	R-HSA-5368287	9.999991e-01	0.000	0	0
TCR signaling	R-HSA-202403	9.999992e-01	0.000	0	0
Antimicrobial peptides	R-HSA-6803157	9.999993e-01	0.000	0	0
Anti-inflammatory response favouring Leishmania parasite infection	R-HSA-9662851	9.999996e-01	0.000	0	0
Leishmania parasite growth and survival	R-HSA-9664433	9.999996e-01	0.000	0	0
Role of phospholipids in phagocytosis	R-HSA-2029485	9.999997e-01	0.000	0	0
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	9.999997e-01	0.000	0	0
Visual phototransduction	R-HSA-2187338	9.999997e-01	0.000	0	0
Translation	R-HSA-72766	9.999999e-01	0.000	0	0
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	9.999999e-01	0.000	0	0
Nucleotide catabolism	R-HSA-8956319	1.000000e+00	0.000	0	0
Hemostasis	R-HSA-109582	1.000000e+00	0.000	1	0
Respiratory electron transport	R-HSA-611105	1.000000e+00	0.000	0	0
Neutrophil degranulation	R-HSA-6798695	1.000000e+00	0.000	0	0
Sensory perception of taste	R-HSA-9717189	1.000000e+00	0.000	0	0
Metabolism of nucleotides	R-HSA-15869	1.000000e+00	0.000	0	0
G alpha (q) signalling events	R-HSA-416476	1.000000e+00	0.000	0	0
Cell surface interactions at the vascular wall	R-HSA-202733	1.000000e+00	0.000	0	0
Diseases of glycosylation	R-HSA-3781865	1.000000e+00	0.000	0	0
Sphingolipid metabolism	R-HSA-428157	1.000000e+00	0.000	0	0
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	1.000000e+00	0.000	0	0
Drug ADME	R-HSA-9748784	1.000000e+00	0.000	0	0
Bacterial Infection Pathways	R-HSA-9824439	1.000000e+00	0.000	0	0
Phase II - Conjugation of compounds	R-HSA-156580	1.000000e+00	0.000	0	0
O-linked glycosylation	R-HSA-5173105	1.000000e+00	0.000	0	0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	R-HSA-198933	1.000000e+00	0.000	0	0
Asparagine N-linked glycosylation	R-HSA-446203	1.000000e+00	0.000	0	0
Cytochrome P450 - arranged by substrate type	R-HSA-211897	1.000000e+00	0.000	0	0
FCERI mediated NF-kB activation	R-HSA-2871837	1.000000e+00	0.000	0	0
Keratinization	R-HSA-6805567	1.000000e+00	0.000	0	0
Post-translational protein modification	R-HSA-597592	1.000000e+00	0.000	0	0
Glycosaminoglycan metabolism	R-HSA-1630316	1.000000e+00	0.000	0	0
Arachidonate metabolism	R-HSA-2142753	1.000000e+00	0.000	0	0
Infection with Enterobacteria	R-HSA-9640148	1.000000e+00	0.000	0	0
Immune System	R-HSA-168256	1.000000e+00	0.000	0	0
Metabolism of vitamins and cofactors	R-HSA-196854	1.000000e+00	0.000	0	0
SLC-mediated transmembrane transport	R-HSA-425407	1.000000e+00	0.000	0	0
Infectious disease	R-HSA-5663205	1.000000e+00	0.000	0	0
GPCR downstream signalling	R-HSA-388396	1.000000e+00	0.000	1	0
Aerobic respiration and respiratory electron transport	R-HSA-1428517	1.000000e+00	0.000	0	0
Metabolism of carbohydrates and carbohydrate derivatives	R-HSA-71387	1.000000e+00	0.000	0	0
G alpha (i) signalling events	R-HSA-418594	1.000000e+00	0.000	1	0
Signaling by GPCR	R-HSA-372790	1.000000e+00	0.000	1	0
Disease	R-HSA-1643685	1.000000e+00	0.000	1	0
Fatty acid metabolism	R-HSA-8978868	1.000000e+00	0.000	0	0
Metabolism of proteins	R-HSA-392499	1.000000e+00	-0.000	0	0
Innate Immune System	R-HSA-168249	1.000000e+00	-0.000	0	0
Olfactory Signaling Pathway	R-HSA-381753	1.000000e+00	-0.000	0	0
Metabolism of lipids	R-HSA-556833	1.000000e+00	-0.000	0	0
Metabolism	R-HSA-1430728	1.000000e+00	-0.000	0	0
Transport of small molecules	R-HSA-382551	1.000000e+00	-0.000	0	0
Sensory Perception	R-HSA-9709957	1.000000e+00	-0.000	0	0
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	1.000000e+00	-0.000	0	0
Metabolism of amino acids and derivatives	R-HSA-71291	1.000000e+00	-0.000	0	0
GPCR ligand binding	R-HSA-500792	1.000000e+00	-0.000	0	0
Diseases of metabolism	R-HSA-5668914	1.000000e+00	-0.000	0	0
Biological oxidations	R-HSA-211859	1.000000e+00	-0.000	0	0
Phase I - Functionalization of compounds	R-HSA-211945	1.000000e+00	-0.000	0	0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK	R-HSA-9931529	1.000000e+00	0.000	1	1

Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download

name	reactome_id	p	-log10p	ref_path	ref_path_lowest
Cell Cycle	R-HSA-1640170	2.240512e-09	8.650	0	0
Cell Cycle, Mitotic	R-HSA-69278	3.137028e-09	8.503	0	0
Chromatin organization	R-HSA-4839726	2.757042e-07	6.560	0	0
M Phase	R-HSA-68886	4.704734e-07	6.327	0	0
Apoptotic execution phase	R-HSA-75153	1.003328e-06	5.999	0	0
Diseases of signal transduction by growth factor receptors and second messengers	R-HSA-5663202	1.441770e-06	5.841	0	0
Transport of Mature Transcript to Cytoplasm	R-HSA-72202	1.804695e-06	5.744	0	0
Chromatin modifying enzymes	R-HSA-3247509	2.054666e-06	5.687	0	0
Transport of the SLBP Dependant Mature mRNA	R-HSA-159230	2.693589e-06	5.570	0	0
Transport of Mature mRNAs Derived from Intronless Transcripts	R-HSA-159234	3.623499e-06	5.441	0	0
Nuclear import of Rev protein	R-HSA-180746	3.558551e-06	5.449	0	0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	R-HSA-5619107	4.352699e-06	5.361	0	0
Transport of Mature mRNA derived from an Intron-Containing Transcript	R-HSA-159236	4.513049e-06	5.346	0	0
IP3 and IP4 transport between cytosol and nucleus	R-HSA-1855196	5.812948e-06	5.236	0	0
IP6 and IP7 transport between cytosol and nucleus	R-HSA-1855229	5.812948e-06	5.236	0	0
Mitotic Prometaphase	R-HSA-68877	6.122997e-06	5.213	0	0
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	R-HSA-2559584	6.736840e-06	5.172	0	0
Vpr-mediated nuclear import of PICs	R-HSA-180910	7.818522e-06	5.107	0	0
IPs transport between nucleus and cytosol	R-HSA-1855170	1.008200e-05	4.996	0	0
Transport of the SLBP independent Mature mRNA	R-HSA-159227	1.008200e-05	4.996	0	0
Rev-mediated nuclear export of HIV RNA	R-HSA-165054	1.001414e-05	4.999	0	0
Transport of Mature mRNA Derived from an Intronless Transcript	R-HSA-159231	1.273828e-05	4.895	0	0
Regulation of Glucokinase by Glucokinase Regulatory Protein	R-HSA-170822	1.310605e-05	4.883	0	0
Nuclear Envelope (NE) Reassembly	R-HSA-2995410	1.469117e-05	4.833	0	0
Interactions of Vpr with host cellular proteins	R-HSA-176033	1.609700e-05	4.793	0	0
Interactions of Rev with host cellular proteins	R-HSA-177243	1.609700e-05	4.793	0	0
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	2.033308e-05	4.692	0	0
Nuclear Pore Complex (NPC) Disassembly	R-HSA-3301854	2.162423e-05	4.665	0	0
Recycling pathway of L1	R-HSA-437239	2.234051e-05	4.651	0	0
Mitotic Anaphase	R-HSA-68882	2.503849e-05	4.601	0	0
Mitotic Metaphase and Anaphase	R-HSA-2555396	2.731996e-05	4.564	0	0
RUNX3 regulates NOTCH signaling	R-HSA-8941856	3.241661e-05	4.489	0	0
Apoptotic cleavage of cellular proteins	R-HSA-111465	3.660510e-05	4.436	0	0
Nuclear Envelope Breakdown	R-HSA-2980766	4.061883e-05	4.391	0	0
Formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	4.847853e-05	4.314	0	0
Apoptosis	R-HSA-109581	4.896118e-05	4.310	0	0
EML4 and NUDC in mitotic spindle formation	R-HSA-9648025	5.468124e-05	4.262	0	0
NS1 Mediated Effects on Host Pathways	R-HSA-168276	5.404104e-05	4.267	0	0
Antiviral mechanism by IFN-stimulated genes	R-HSA-1169410	5.322339e-05	4.274	0	0
Regulation of NFE2L2 gene expression	R-HSA-9818749	6.692894e-05	4.174	0	0
Transport of Ribonucleoproteins into the Host Nucleus	R-HSA-168271	8.225718e-05	4.085	0	0
Formation of WDR5-containing histone-modifying complexes	R-HSA-9772755	9.332646e-05	4.030	0	0
tRNA processing in the nucleus	R-HSA-6784531	9.493928e-05	4.023	0	0
Cellular response to heat stress	R-HSA-3371556	1.043652e-04	3.981	0	0
NOTCH3 Intracellular Domain Regulates Transcription	R-HSA-9013508	1.014587e-04	3.994	0	0
Activation of BH3-only proteins	R-HSA-114452	1.014587e-04	3.994	0	0
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	1.043652e-04	3.981	0	0
Formation of the embryonic stem cell BAF (esBAF) complex	R-HSA-9933946	1.057351e-04	3.976	0	0
Epigenetic regulation of gene expression	R-HSA-212165	1.152414e-04	3.938	1	0
NOTCH1 Intracellular Domain Regulates Transcription	R-HSA-2122947	1.227464e-04	3.911	0	0
Deactivation of the beta-catenin transactivating complex	R-HSA-3769402	1.428810e-04	3.845	0	0
Diseases of mitotic cell cycle	R-HSA-9675126	1.612367e-04	3.793	0	0
Translocation of SLC2A4 (GLUT4) to the plasma membrane	R-HSA-1445148	1.589851e-04	3.799	0	0
NOTCH4 Intracellular Domain Regulates Transcription	R-HSA-9013695	1.719617e-04	3.765	0	0
Regulation of beta-cell development	R-HSA-186712	1.927687e-04	3.715	0	0
NEP/NS2 Interacts with the Cellular Export Machinery	R-HSA-168333	2.139343e-04	3.670	0	0
Export of Viral Ribonucleoproteins from Nucleus	R-HSA-168274	2.552624e-04	3.593	0	0
Viral Messenger RNA Synthesis	R-HSA-168325	2.621322e-04	3.581	0	0
Signal Transduction	R-HSA-162582	2.880277e-04	3.541	1	0
Regulation of HSF1-mediated heat shock response	R-HSA-3371453	3.991786e-04	3.399	0	0
MITF-M-regulated melanocyte development	R-HSA-9730414	4.058506e-04	3.392	0	0
Recruitment of NuMA to mitotic centrosomes	R-HSA-380320	4.443046e-04	3.352	0	0
Positive Regulation of CDH1 Gene Transcription	R-HSA-9764790	4.743968e-04	3.324	0	0
Activation of BAD and translocation to mitochondria	R-HSA-111447	6.197656e-04	3.208	0	0
SWI/SNF chromatin remodelers	R-HSA-9932451	6.064008e-04	3.217	0	0
ATP-dependent chromatin remodelers	R-HSA-9932444	6.064008e-04	3.217	0	0
Cell-extracellular matrix interactions	R-HSA-446353	6.197656e-04	3.208	0	0
Mitotic Prophase	R-HSA-68875	5.688572e-04	3.245	0	0
Cellular Senescence	R-HSA-2559583	5.714180e-04	3.243	0	0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	R-HSA-9735871	6.197656e-04	3.208	0	0
ISG15 antiviral mechanism	R-HSA-1169408	6.055441e-04	3.218	0	0
Post-chaperonin tubulin folding pathway	R-HSA-389977	6.474469e-04	3.189	0	0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	R-HSA-9934037	6.474469e-04	3.189	0	0
Separation of Sister Chromatids	R-HSA-2467813	6.704851e-04	3.174	0	0
HATs acetylate histones	R-HSA-3214847	7.311056e-04	3.136	0	0
Expression of BMAL (ARNTL), CLOCK, and NPAS2	R-HSA-9931509	7.806124e-04	3.108	0	0
HIV Life Cycle	R-HSA-162587	8.170185e-04	3.088	0	0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	8.334543e-04	3.079	0	0
HCMV Early Events	R-HSA-9609690	9.121513e-04	3.040	0	0
Programmed Cell Death	R-HSA-5357801	9.231184e-04	3.035	0	0
Aggrephagy	R-HSA-9646399	9.263869e-04	3.033	0	0
Transcriptional regulation by RUNX1	R-HSA-8878171	9.957503e-04	3.002	0	0
Activation of AMPK downstream of NMDARs	R-HSA-9619483	1.148172e-03	2.940	0	0
Late Phase of HIV Life Cycle	R-HSA-162599	1.119059e-03	2.951	0	0
Membrane Trafficking	R-HSA-199991	1.162837e-03	2.934	0	0
Transcriptional regulation by small RNAs	R-HSA-5578749	1.156904e-03	2.937	0	0
Developmental Biology	R-HSA-1266738	1.184393e-03	2.927	1	0
Signaling by BRAF and RAF1 fusions	R-HSA-6802952	1.351985e-03	2.869	0	0
Gap junction trafficking and regulation	R-HSA-157858	1.355402e-03	2.868	0	0
Epigenetic regulation by WDR5-containing histone modifying complexes	R-HSA-9917777	1.365653e-03	2.865	1	0
Repression of WNT target genes	R-HSA-4641265	1.370457e-03	2.863	0	0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	R-HSA-190840	1.432756e-03	2.844	0	0
Gene expression (Transcription)	R-HSA-74160	1.466772e-03	2.834	1	0
Aberrant regulation of mitotic cell cycle due to RB1 defects	R-HSA-9687139	1.689173e-03	2.772	0	0
NFE2L2 regulating tumorigenic genes	R-HSA-9818030	1.854143e-03	2.732	0	0
Signaling by high-kinase activity BRAF mutants	R-HSA-6802948	1.918269e-03	2.717	0	0
Oncogenic MAPK signaling	R-HSA-6802957	1.916126e-03	2.718	0	0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	R-HSA-75035	1.854143e-03	2.732	0	0
Signaling by NOTCH1	R-HSA-1980143	1.843259e-03	2.734	0	0
Transport of connexons to the plasma membrane	R-HSA-190872	1.837094e-03	2.736	0	0
Metabolism of non-coding RNA	R-HSA-194441	1.784331e-03	2.749	0	0
snRNP Assembly	R-HSA-191859	1.784331e-03	2.749	0	0
Mitotic Spindle Checkpoint	R-HSA-69618	1.962281e-03	2.707	0	0
Formation of the dystrophin-glycoprotein complex (DGC)	R-HSA-9913351	2.027371e-03	2.693	0	0
Gap junction trafficking	R-HSA-190828	2.032977e-03	2.692	0	0
L1CAM interactions	R-HSA-373760	2.087588e-03	2.680	0	0
MITF-M-dependent gene expression	R-HSA-9856651	2.095541e-03	2.679	0	0
Caspase-mediated cleavage of cytoskeletal proteins	R-HSA-264870	2.172601e-03	2.663	0	0
Formation of the polybromo-BAF (pBAF) complex	R-HSA-9933939	2.457147e-03	2.610	0	0
Clathrin-mediated endocytosis	R-HSA-8856828	2.560892e-03	2.592	0	0
Regulation of CDH1 Gene Transcription	R-HSA-9764560	2.454997e-03	2.610	0	0
Transcriptional regulation of granulopoiesis	R-HSA-9616222	2.588214e-03	2.587	0	0
Signaling downstream of RAS mutants	R-HSA-9649948	2.703469e-03	2.568	0	0
Signaling by moderate kinase activity BRAF mutants	R-HSA-6802946	2.703469e-03	2.568	0	0
Paradoxical activation of RAF signaling by kinase inactive BRAF	R-HSA-6802955	2.703469e-03	2.568	0	0
Signaling by RAS mutants	R-HSA-6802949	2.703469e-03	2.568	0	0
Inositol phosphate metabolism	R-HSA-1483249	2.774932e-03	2.557	0	0
Signaling by NTRK1 (TRKA)	R-HSA-187037	2.810587e-03	2.551	1	0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	R-HSA-8939243	2.864907e-03	2.543	0	0
Apoptosis induced DNA fragmentation	R-HSA-140342	3.053612e-03	2.515	0	0
RUNX1 regulates expression of components of tight junctions	R-HSA-8935964	3.156869e-03	2.501	0	0
Signaling by NOTCH3	R-HSA-9012852	3.040707e-03	2.517	0	0
NRAGE signals death through JNK	R-HSA-193648	3.440854e-03	2.463	0	0
Intrinsic Pathway for Apoptosis	R-HSA-109606	3.440854e-03	2.463	0	0
Mitotic G2-G2/M phases	R-HSA-453274	3.936044e-03	2.405	0	0
Signaling by ALK fusions and activated point mutants	R-HSA-9725370	4.019003e-03	2.396	0	0
Signaling by ALK in cancer	R-HSA-9700206	4.019003e-03	2.396	0	0
MAP2K and MAPK activation	R-HSA-5674135	4.076238e-03	2.390	0	0
Signaling by RAF1 mutants	R-HSA-9656223	4.076238e-03	2.390	0	0
AURKA Activation by TPX2	R-HSA-8854518	4.098335e-03	2.387	0	0
Regulation of PD-L1(CD274) transcription	R-HSA-9909649	4.098335e-03	2.387	0	0
Amplification of signal from the kinetochores	R-HSA-141424	5.133641e-03	2.290	0	0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	R-HSA-141444	5.133641e-03	2.290	0	0
mTORC1-mediated signalling	R-HSA-166208	5.330835e-03	2.273	0	0
Transcriptional Regulation by TP53	R-HSA-3700989	5.887182e-03	2.230	1	0
Signaling by Hippo	R-HSA-2028269	6.414342e-03	2.193	0	0
Heme signaling	R-HSA-9707616	6.820326e-03	2.166	0	0
Activation of PUMA and translocation to mitochondria	R-HSA-139915	6.870293e-03	2.163	0	0
Role of ABL in ROBO-SLIT signaling	R-HSA-428890	6.870293e-03	2.163	0	0
Binding of TCF/LEF:CTNNB1 to target gene promoters	R-HSA-4411364	6.870293e-03	2.163	0	0
SHOC2 M1731 mutant abolishes MRAS complex function	R-HSA-9726840	6.870293e-03	2.163	0	0
RUNX3 regulates WNT signaling	R-HSA-8951430	6.870293e-03	2.163	0	0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	R-HSA-389958	6.973406e-03	2.157	0	0
NOTCH2 intracellular domain regulates transcription	R-HSA-2197563	7.212553e-03	2.142	0	0
Signaling by NTRKs	R-HSA-166520	7.265138e-03	2.139	1	0
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	7.576807e-03	2.121	0	0
Loss of Nlp from mitotic centrosomes	R-HSA-380259	7.576807e-03	2.121	0	0
Formation of tubulin folding intermediates by CCT/TriC	R-HSA-389960	7.632340e-03	2.117	0	0
COPI-independent Golgi-to-ER retrograde traffic	R-HSA-6811436	8.224788e-03	2.085	0	0
Axon guidance	R-HSA-422475	8.823926e-03	2.054	1	0
Cell death signalling via NRAGE, NRIF and NADE	R-HSA-204998	8.391913e-03	2.076	0	0
Formation of the non-canonical BAF (ncBAF) complex	R-HSA-9933947	9.203941e-03	2.036	0	0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	R-HSA-9659787	9.203941e-03	2.036	0	0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	R-HSA-9661069	9.203941e-03	2.036	0	0
Nervous system development	R-HSA-9675108	9.482233e-03	2.023	1	0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	R-HSA-111453	9.499251e-03	2.022	0	0
Signaling by MRAS-complex mutants	R-HSA-9660537	9.499251e-03	2.022	0	0
Formation of annular gap junctions	R-HSA-196025	9.499251e-03	2.022	0	0
Gain-of-function MRAS complexes activate RAF signaling	R-HSA-9726842	9.499251e-03	2.022	0	0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence	R-HSA-9825895	9.499251e-03	2.022	0	0
Alternative Lengthening of Telomeres (ALT)	R-HSA-9006821	9.864995e-03	2.006	0	0
Defective Inhibition of DNA Recombination at Telomere	R-HSA-9670621	9.864995e-03	2.006	0	0
Diseases of Telomere Maintenance	R-HSA-9673013	9.864995e-03	2.006	0	0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	R-HSA-9670613	9.864995e-03	2.006	0	0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations	R-HSA-9670615	9.864995e-03	2.006	0	0
NFE2L2 regulating ER-stress associated genes	R-HSA-9818035	1.039258e-02	1.983	0	0
Transcription of E2F targets under negative control by DREAM complex	R-HSA-1362277	1.151042e-02	1.939	0	0
Postmitotic nuclear pore complex (NPC) reformation	R-HSA-9615933	1.059575e-02	1.975	0	0
Formation of the canonical BAF (cBAF) complex	R-HSA-9933937	1.154483e-02	1.938	0	0
PKMTs methylate histone lysines	R-HSA-3214841	1.046922e-02	1.980	0	0
G2/M Transition	R-HSA-69275	1.173032e-02	1.931	0	0
Cell Cycle Checkpoints	R-HSA-69620	1.061295e-02	1.974	0	0
GP1b-IX-V activation signalling	R-HSA-430116	1.270742e-02	1.896	0	0
Gap junction degradation	R-HSA-190873	1.270742e-02	1.896	0	0
MTOR signalling	R-HSA-165159	1.332004e-02	1.875	0	0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	R-HSA-2894862	1.380700e-02	1.860	0	0
Constitutive Signaling by NOTCH1 PEST Domain Mutants	R-HSA-2644606	1.380700e-02	1.860	0	0
Signaling by NOTCH1 PEST Domain Mutants in Cancer	R-HSA-2644602	1.380700e-02	1.860	0	0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	R-HSA-2894858	1.380700e-02	1.860	0	0
Signaling by NOTCH1 in Cancer	R-HSA-2644603	1.380700e-02	1.860	0	0
Kinesins	R-HSA-983189	1.380700e-02	1.860	0	0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways	R-HSA-9755779	1.426086e-02	1.846	0	0
NFE2L2 regulating inflammation associated genes	R-HSA-9818026	1.563808e-02	1.806	0	0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	R-HSA-9673768	1.563808e-02	1.806	0	0
MET activates RAP1 and RAC1	R-HSA-8875555	1.653450e-02	1.782	0	0
Aberrant regulation of mitotic exit in cancer due to RB1 defects	R-HSA-9687136	1.737550e-02	1.760	0	0
Initiation of Nuclear Envelope (NE) Reformation	R-HSA-2995383	1.618412e-02	1.791	0	0
mRNA 3'-end processing	R-HSA-72187	1.526897e-02	1.816	0	0
Positive epigenetic regulation of rRNA expression	R-HSA-5250913	1.624545e-02	1.789	0	0
RNA Polymerase II Transcription Termination	R-HSA-73856	1.520329e-02	1.818	0	0
Prolonged ERK activation events	R-HSA-169893	1.737550e-02	1.760	0	0
Regulation of gene expression in beta cells	R-HSA-210745	1.649161e-02	1.783	0	0
Selective autophagy	R-HSA-9663891	1.489590e-02	1.827	0	0
Signaling by Receptor Tyrosine Kinases	R-HSA-9006934	1.697239e-02	1.770	1	0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	R-HSA-9825892	1.618412e-02	1.791	0	0
Cell junction organization	R-HSA-446728	1.589429e-02	1.799	0	0
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	1.739496e-02	1.760	0	0
Gene Silencing by RNA	R-HSA-211000	1.766958e-02	1.753	0	0
mRNA Splicing - Major Pathway	R-HSA-72163	1.781434e-02	1.749	0	0
Regulation of Expression and Function of Type I Classical Cadherins	R-HSA-9764274	1.818802e-02	1.740	0	0
Regulation of CDH1 Expression and Function	R-HSA-9764265	1.818802e-02	1.740	0	0
p75 NTR receptor-mediated signalling	R-HSA-193704	1.892357e-02	1.723	0	0
Notch-HLH transcription pathway	R-HSA-350054	1.895195e-02	1.722	0	0
Cell-Cell communication	R-HSA-1500931	1.904240e-02	1.720	0	0
HIV Infection	R-HSA-162906	1.906772e-02	1.720	0	0
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	1.927310e-02	1.715	0	0
HCMV Infection	R-HSA-9609646	1.991102e-02	1.701	0	0
G2/M DNA damage checkpoint	R-HSA-69473	2.093602e-02	1.679	0	0
Regulation of localization of FOXO transcription factors	R-HSA-9614399	2.101297e-02	1.678	0	0
Breakdown of the nuclear lamina	R-HSA-352238	2.114872e-02	1.675	0	0
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	2.147475e-02	1.668	0	0
Estrogen-dependent gene expression	R-HSA-9018519	2.170287e-02	1.663	0	0
Prefoldin mediated transfer of substrate to CCT/TriC	R-HSA-389957	2.202627e-02	1.657	0	0
Negative feedback regulation of MAPK pathway	R-HSA-5674499	2.212450e-02	1.655	0	0
Centrosome maturation	R-HSA-380287	2.270307e-02	1.644	0	0
Non-integrin membrane-ECM interactions	R-HSA-3000171	2.270307e-02	1.644	0	0
TP53 Regulates Transcription of Cell Cycle Genes	R-HSA-6791312	2.474049e-02	1.607	0	0
NGF-stimulated transcription	R-HSA-9031628	2.531049e-02	1.597	1	1
Nuclear events stimulated by ALK signaling in cancer	R-HSA-9725371	2.531049e-02	1.597	0	0
RUNX3 regulates YAP1-mediated transcription	R-HSA-8951671	2.986353e-02	1.525	0	0
DNA Damage Recognition in GG-NER	R-HSA-5696394	3.091710e-02	1.510	0	0
mRNA Splicing	R-HSA-72172	2.995626e-02	1.524	0	0
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	3.067262e-02	1.513	0	0
RUNX1 regulates transcription of genes involved in WNT signaling	R-HSA-8939256	2.986353e-02	1.525	0	0
AKT phosphorylates targets in the cytosol	R-HSA-198323	3.201772e-02	1.495	0	0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	R-HSA-3371497	2.811399e-02	1.551	0	0
TGFBR3 expression	R-HSA-9839394	2.914505e-02	1.535	0	0
Host Interactions of HIV factors	R-HSA-162909	3.058406e-02	1.515	0	0
Sensory processing of sound by inner hair cells of the cochlea	R-HSA-9662360	2.811399e-02	1.551	0	0
G alpha (12/13) signalling events	R-HSA-416482	2.866345e-02	1.543	0	0
Sealing of the nuclear envelope (NE) by ESCRT-III	R-HSA-9668328	2.752636e-02	1.560	0	0
Assembly and cell surface presentation of NMDA receptors	R-HSA-9609736	3.120814e-02	1.506	0	0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)	R-HSA-9845323	3.212870e-02	1.493	0	0
Transcriptional regulation by RUNX3	R-HSA-8878159	3.274399e-02	1.485	0	0
Regulation of Homotypic Cell-Cell Adhesion	R-HSA-9759476	3.282637e-02	1.484	0	0
Cellular responses to stress	R-HSA-2262752	3.342178e-02	1.476	0	0
Organelle biogenesis and maintenance	R-HSA-1852241	3.364776e-02	1.473	0	0
Rap1 signalling	R-HSA-392517	3.420335e-02	1.466	0	0
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	3.438413e-02	1.464	1	1
Interleukin-3, Interleukin-5 and GM-CSF signaling	R-HSA-512988	3.448250e-02	1.462	0	0
RAF activation	R-HSA-5673000	3.457731e-02	1.461	0	0
Developmental Lineage of Mammary Gland Alveolar Cells	R-HSA-9927426	3.457731e-02	1.461	0	0
Gap junction assembly	R-HSA-190861	3.457731e-02	1.461	0	0
Metabolism of RNA	R-HSA-8953854	3.488025e-02	1.457	0	0
Cargo trafficking to the periciliary membrane	R-HSA-5620920	3.555088e-02	1.449	0	0
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	3.568150e-02	1.448	0	0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	R-HSA-446343	3.583438e-02	1.446	0	0
Developmental Cell Lineages of the Integumentary System	R-HSA-9734779	3.632638e-02	1.440	0	0
Neurexins and neuroligins	R-HSA-6794361	3.665781e-02	1.436	0	0
DNA Damage/Telomere Stress Induced Senescence	R-HSA-2559586	3.784007e-02	1.422	0	0
Developmental Lineages of the Mammary Gland	R-HSA-9924644	3.831092e-02	1.417	0	0
Signalling to ERKs	R-HSA-187687	3.851394e-02	1.414	0	0
Formation of axial mesoderm	R-HSA-9796292	3.857319e-02	1.414	0	0
Frs2-mediated activation	R-HSA-170968	3.857319e-02	1.414	0	0
RUNX1 regulates estrogen receptor mediated transcription	R-HSA-8931987	3.884370e-02	1.411	0	0
SOS-mediated signalling	R-HSA-112412	3.884370e-02	1.411	0	0
Displacement of DNA glycosylase by APEX1	R-HSA-110357	3.884370e-02	1.411	0	0
Glycolysis	R-HSA-70171	3.956478e-02	1.403	0	0
Cilium Assembly	R-HSA-5617833	4.108906e-02	1.386	0	0
ER to Golgi Anterograde Transport	R-HSA-199977	4.119613e-02	1.385	0	0
RUNX2 regulates osteoblast differentiation	R-HSA-8940973	4.240401e-02	1.373	0	0
MET interacts with TNS proteins	R-HSA-8875513	5.338181e-02	1.273	0	0
Type I hemidesmosome assembly	R-HSA-446107	4.903473e-02	1.309	0	0
Activation of the pre-replicative complex	R-HSA-68962	5.305162e-02	1.275	0	0
Regulation of endogenous retroelements	R-HSA-9842860	4.463923e-02	1.350	0	0
RNA Polymerase II Pre-transcription Events	R-HSA-674695	4.427194e-02	1.354	0	0
MET promotes cell motility	R-HSA-8875878	5.203939e-02	1.284	0	0
Adipogenesis	R-HSA-9843745	4.963069e-02	1.304	0	0
Golgi-to-ER retrograde transport	R-HSA-8856688	5.217062e-02	1.283	0	0
CRMPs in Sema3A signaling	R-HSA-399956	4.583900e-02	1.339	1	1
Protein folding	R-HSA-391251	4.306243e-02	1.366	0	0
Regulation of MITF-M dependent genes involved in metabolism	R-HSA-9854907	5.338181e-02	1.273	0	0
S Phase	R-HSA-69242	4.325984e-02	1.364	0	0
RET signaling	R-HSA-8853659	4.273314e-02	1.369	0	0
Protein-protein interactions at synapses	R-HSA-6794362	4.682316e-02	1.330	0	0
Macroautophagy	R-HSA-1632852	4.986061e-02	1.302	0	0
MHC class II antigen presentation	R-HSA-2132295	5.179874e-02	1.286	0	0
Apoptotic cleavage of cell adhesion proteins	R-HSA-351906	4.903473e-02	1.309	0	0
Sensory processing of sound by outer hair cells of the cochlea	R-HSA-9662361	5.106947e-02	1.292	0	0
Interleukin-37 signaling	R-HSA-9008059	5.305162e-02	1.275	0	0
Adherens junctions interactions	R-HSA-418990	5.346010e-02	1.272	0	0
Processive synthesis on the lagging strand	R-HSA-69183	5.381351e-02	1.269	0	0
Chaperonin-mediated protein folding	R-HSA-390466	5.660655e-02	1.247	0	0
Transcriptional Regulation by E2F6	R-HSA-8953750	5.713429e-02	1.243	0	0
Signaling by ALK	R-HSA-201556	5.713429e-02	1.243	0	0
COPI-mediated anterograde transport	R-HSA-6807878	5.820397e-02	1.235	0	0
COPI-dependent Golgi-to-ER retrograde traffic	R-HSA-6811434	5.820397e-02	1.235	0	0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	R-HSA-8936459	5.906735e-02	1.229	0	0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes	R-HSA-9851695	6.027507e-02	1.220	1	0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	R-HSA-9841922	6.027507e-02	1.220	1	1
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	R-HSA-9818564	6.027507e-02	1.220	1	0
NFE2L2 regulating MDR associated enzymes	R-HSA-9818032	6.039120e-02	1.219	0	0
ARMS-mediated activation	R-HSA-170984	6.039120e-02	1.219	0	0
Inactivation of CDC42 and RAC1	R-HSA-428543	6.039120e-02	1.219	0	0
Sensory processing of sound	R-HSA-9659379	6.187167e-02	1.209	0	0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	R-HSA-6804116	6.248939e-02	1.204	0	0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	R-HSA-73779	6.252738e-02	1.204	0	0
DNA strand elongation	R-HSA-69190	6.518493e-02	1.186	0	0
G0 and Early G1	R-HSA-1538133	6.518493e-02	1.186	0	0
Mitotic G1 phase and G1/S transition	R-HSA-453279	6.584391e-02	1.181	0	0
PKR-mediated signaling	R-HSA-9833482	6.587148e-02	1.181	0	0
Constitutive Signaling by AKT1 E17K in Cancer	R-HSA-5674400	6.594098e-02	1.181	0	0
M-decay: degradation of maternal mRNAs by maternally stored factors	R-HSA-9820841	6.822030e-02	1.166	0	0
Resolution of Abasic Sites (AP sites)	R-HSA-73933	6.822030e-02	1.166	0	0
Transcriptional Regulation by VENTX	R-HSA-8853884	6.822030e-02	1.166	0	0
Regulation of PTEN gene transcription	R-HSA-8943724	6.877348e-02	1.163	0	0
Vesicle-mediated transport	R-HSA-5653656	7.111359e-02	1.148	0	0
Deletions in the AXIN1 gene destabilize the destruction complex	R-HSA-5467345	7.112153e-02	1.148	0	0
Defective translocation of RB1 mutants to the nucleus	R-HSA-9661070	7.112153e-02	1.148	0	0
APC truncation mutants are not K63 polyubiquitinated	R-HSA-5467333	7.112153e-02	1.148	0	0
Inhibition of TSC complex formation by PKB	R-HSA-165181	7.331035e-02	1.135	0	0
IRS activation	R-HSA-74713	9.519314e-02	1.021	0	0
G2 Phase	R-HSA-68911	9.519314e-02	1.021	0	0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex	R-HSA-9931521	7.185406e-02	1.144	0	0
Inactivation of APC/C via direct inhibition of the APC/C complex	R-HSA-141430	7.185406e-02	1.144	0	0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	R-HSA-176407	8.189019e-02	1.087	0	0
Deadenylation of mRNA	R-HSA-429947	7.375515e-02	1.132	0	0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	R-HSA-9931510	9.081825e-02	1.042	0	0
RNA Polymerase II HIV Promoter Escape	R-HSA-167162	7.421370e-02	1.130	0	0
HIV Transcription Initiation	R-HSA-167161	7.421370e-02	1.130	0	0
RNA Polymerase II Transcription Initiation	R-HSA-75953	7.421370e-02	1.130	0	0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells	R-HSA-9927418	8.050737e-02	1.094	0	0
RNA Polymerase II Promoter Escape	R-HSA-73776	8.710013e-02	1.060	0	0
B-WICH complex positively regulates rRNA expression	R-HSA-5250924	8.621865e-02	1.064	0	0
EPHB-mediated forward signaling	R-HSA-3928662	9.398996e-02	1.027	0	0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	R-HSA-5358565	8.189019e-02	1.087	0	0
Global Genome Nucleotide Excision Repair (GG-NER)	R-HSA-5696399	8.351926e-02	1.078	0	0
Nuclear RNA decay	R-HSA-9930044	7.181168e-02	1.144	0	0
Signal attenuation	R-HSA-74749	7.285583e-02	1.138	0	0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	R-HSA-141405	7.185406e-02	1.144	0	0
Negative regulation of MAPK pathway	R-HSA-5675221	7.421370e-02	1.130	0	0
Myogenesis	R-HSA-525793	9.081825e-02	1.042	0	0
Mismatch Repair	R-HSA-5358508	9.257629e-02	1.034	0	0
PTK6 Regulates Proteins Involved in RNA Processing	R-HSA-8849468	9.519314e-02	1.021	0	0
Signaling by cytosolic FGFR1 fusion mutants	R-HSA-1839117	9.257629e-02	1.034	0	0
CD209 (DC-SIGN) signaling	R-HSA-5621575	7.375515e-02	1.132	0	0
Cargo recognition for clathrin-mediated endocytosis	R-HSA-8856825	8.920531e-02	1.050	0	0
Signaling by NOTCH4	R-HSA-9013694	8.684631e-02	1.061	0	0
Semaphorin interactions	R-HSA-373755	8.428965e-02	1.074	1	0
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	7.683849e-02	1.114	1	0
Signaling by NOTCH	R-HSA-157118	7.772360e-02	1.109	0	0
Deubiquitination	R-HSA-5688426	8.636824e-02	1.064	0	0
HDMs demethylate histones	R-HSA-3214842	8.205031e-02	1.086	0	0
RNA Polymerase II Transcription	R-HSA-73857	8.116907e-02	1.091	1	0
FOXO-mediated transcription of cell death genes	R-HSA-9614657	9.257629e-02	1.034	0	0
Uptake and function of anthrax toxins	R-HSA-5210891	8.189019e-02	1.087	0	0
Transcriptional and post-translational regulation of MITF-M expression and activity	R-HSA-9856649	7.211630e-02	1.142	0	0
Regulation of TP53 Activity	R-HSA-5633007	7.407843e-02	1.130	1	0
SARS-CoV-2 activates/modulates innate and adaptive immune responses	R-HSA-9705671	8.993476e-02	1.046	0	0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	R-HSA-8864260	9.398996e-02	1.027	0	0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	R-HSA-3134973	9.519314e-02	1.021	0	0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	R-HSA-9926550	9.257629e-02	1.034	0	0
Death Receptor Signaling	R-HSA-73887	9.212271e-02	1.036	0	0
UCH proteinases	R-HSA-5689603	9.760605e-02	1.011	0	0
Autophagy	R-HSA-9612973	9.961170e-02	1.002	0	0
NFE2L2 regulates pentose phosphate pathway genes	R-HSA-9818028	1.008374e-01	0.996	0	0
Anchoring fibril formation	R-HSA-2214320	1.008374e-01	0.996	0	0
Inhibition of replication initiation of damaged DNA by RB1/E2F1	R-HSA-113501	1.008374e-01	0.996	0	0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters	R-HSA-9931512	1.008374e-01	0.996	0	0
Signaling by AXIN mutants	R-HSA-4839735	1.008374e-01	0.996	0	0
Activation of RAC1	R-HSA-428540	1.008374e-01	0.996	0	0
RNA Polymerase II Transcription Initiation And Promoter Clearance	R-HSA-76042	1.011739e-01	0.995	0	0
RUNX2 regulates bone development	R-HSA-8941326	1.020044e-01	0.991	0	0
Post NMDA receptor activation events	R-HSA-438064	1.038322e-01	0.984	0	0
Regulation of signaling by CBL	R-HSA-912631	1.038871e-01	0.983	0	0
Signaling by EGFR	R-HSA-177929	1.055351e-01	0.977	0	0
mRNA Splicing - Minor Pathway	R-HSA-72165	1.086483e-01	0.964	0	0
TP53 Regulates Transcription of DNA Repair Genes	R-HSA-6796648	1.091137e-01	0.962	0	0
Glucose metabolism	R-HSA-70326	1.114322e-01	0.953	0	0
Transcription of the HIV genome	R-HSA-167172	1.144320e-01	0.941	0	0
VxPx cargo-targeting to cilium	R-HSA-5620916	1.157942e-01	0.936	0	0
RUNX3 regulates p14-ARF	R-HSA-8951936	1.162035e-01	0.935	0	0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	R-HSA-9820865	1.162035e-01	0.935	0	0
Regulation of FOXO transcriptional activity by acetylation	R-HSA-9617629	1.162035e-01	0.935	0	0
Signaling by LTK	R-HSA-9842663	1.162035e-01	0.935	0	0
Carboxyterminal post-translational modifications of tubulin	R-HSA-8955332	1.164084e-01	0.934	0	0
TCF dependent signaling in response to WNT	R-HSA-201681	1.180152e-01	0.928	0	0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	R-HSA-446388	1.186519e-01	0.926	0	0
FOXO-mediated transcription	R-HSA-9614085	1.196788e-01	0.922	0	0
Signaling by MET	R-HSA-6806834	1.213599e-01	0.916	0	0
Assembly of collagen fibrils and other multimeric structures	R-HSA-2022090	1.270415e-01	0.896	0	0
Degradation of beta-catenin by the destruction complex	R-HSA-195253	1.279567e-01	0.893	0	0
Lagging Strand Synthesis	R-HSA-69186	1.282666e-01	0.892	0	0
APC-Cdc20 mediated degradation of Nek2A	R-HSA-179409	1.282666e-01	0.892	0	0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	R-HSA-9933387	1.303809e-01	0.885	0	0
Negative Regulation of CDH1 Gene Transcription	R-HSA-9764725	1.346806e-01	0.871	0	0
Regulation of PAK-2p34 activity by PS-GAP/RHG10	R-HSA-211728	1.371887e-01	0.863	0	0
Defective Mismatch Repair Associated With MSH6	R-HSA-5632968	1.371887e-01	0.863	0	0
Circadian clock	R-HSA-9909396	1.390948e-01	0.857	1	0
Intra-Golgi and retrograde Golgi-to-ER traffic	R-HSA-6811442	1.392372e-01	0.856	0	0
Gap-filling DNA repair synthesis and ligation in GG-NER	R-HSA-5696397	1.412706e-01	0.850	0	0
Signaling by PDGFR in disease	R-HSA-9671555	1.412706e-01	0.850	0	0
Maternal to zygotic transition (MZT)	R-HSA-9816359	1.425443e-01	0.846	0	0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	R-HSA-8869496	1.433522e-01	0.844	0	0
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	R-HSA-210746	1.433522e-01	0.844	0	0
Cellular responses to stimuli	R-HSA-8953897	1.446737e-01	0.840	0	0
Influenza Viral RNA Transcription and Replication	R-HSA-168273	1.467596e-01	0.833	0	0
Defective VWF binding to collagen type I	R-HSA-9845622	1.985605e-01	0.702	0	0
Defective MMADHC causes MMAHCD	R-HSA-3359473	1.985605e-01	0.702	0	0
NOSTRIN mediated eNOS trafficking	R-HSA-203641	1.689992e-01	0.772	0	0
MET receptor recycling	R-HSA-8875656	1.953336e-01	0.709	0	0
MAP3K8 (TPL2)-dependent MAPK1/3 activation	R-HSA-5684264	1.492842e-01	0.826	0	0
Removal of the Flap Intermediate	R-HSA-69166	1.492842e-01	0.826	0	0
Retrograde neurotrophin signalling	R-HSA-177504	1.492842e-01	0.826	0	0
Calcineurin activates NFAT	R-HSA-2025928	2.221280e-01	0.653	0	0
ALK mutants bind TKIs	R-HSA-9700645	2.221280e-01	0.653	0	0
Erythropoietin activates RAS	R-HSA-9027284	1.668342e-01	0.778	0	0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	R-HSA-1362300	1.849479e-01	0.733	0	0
GRB2:SOS provides linkage to MAPK signaling for Integrins	R-HSA-354194	1.849479e-01	0.733	0	0
Phosphorylation of the APC/C	R-HSA-176412	1.849479e-01	0.733	0	0
Processing of Intronless Pre-mRNAs	R-HSA-77595	2.035453e-01	0.691	0	0
Striated Muscle Contraction	R-HSA-390522	1.763563e-01	0.754	0	0
RNA polymerase II transcribes snRNA genes	R-HSA-6807505	1.697807e-01	0.770	0	0
Developmental Lineage of Pancreatic Ductal Cells	R-HSA-9925563	2.129405e-01	0.672	0	0
Nucleotide Excision Repair	R-HSA-5696398	1.620201e-01	0.790	0	0
Integrin signaling	R-HSA-354192	1.643274e-01	0.784	0	0
Cyclin D associated events in G1	R-HSA-69231	1.895553e-01	0.722	0	0
G1 Phase	R-HSA-69236	1.895553e-01	0.722	0	0
Platelet Aggregation (Plug Formation)	R-HSA-76009	2.007036e-01	0.697	0	0
Recognition of DNA damage by PCNA-containing replication complex	R-HSA-110314	1.831146e-01	0.737	0	0
TRAF3-dependent IRF activation pathway	R-HSA-918233	2.035453e-01	0.691	0	0
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	1.831146e-01	0.737	0	0
RNA Polymerase III Abortive And Retractive Initiation	R-HSA-749476	2.142807e-01	0.669	0	0
RNA Polymerase III Transcription	R-HSA-74158	2.142807e-01	0.669	0	0
Adrenoceptors	R-HSA-390696	1.953336e-01	0.709	0	0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	R-HSA-450513	1.668342e-01	0.778	0	0
Golgi Associated Vesicle Biogenesis	R-HSA-432722	1.686202e-01	0.773	0	0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	R-HSA-450385	1.668342e-01	0.778	0	0
RNA Polymerase I Transcription Initiation	R-HSA-73762	1.680177e-01	0.775	0	0
Chromosome Maintenance	R-HSA-73886	2.038240e-01	0.691	0	0
Signaling by FLT3 fusion proteins	R-HSA-9703465	2.129937e-01	0.672	0	0
STAT3 nuclear events downstream of ALK signaling	R-HSA-9701898	1.668342e-01	0.778	0	0
Defective Mismatch Repair Associated With MSH2	R-HSA-5632928	1.985605e-01	0.702	0	0
Regulation of KIT signaling	R-HSA-1433559	1.492842e-01	0.826	0	0
Activation of RAC1 downstream of NMDARs	R-HSA-9619229	2.221280e-01	0.653	0	0
Unwinding of DNA	R-HSA-176974	2.221280e-01	0.653	0	0
Disorders of Developmental Biology	R-HSA-9675151	2.035453e-01	0.691	0	0
Regulation of TP53 Activity through Acetylation	R-HSA-6804758	1.643274e-01	0.784	0	0
G2/M Checkpoints	R-HSA-69481	1.717321e-01	0.765	0	0
Signaling by FGFR1 in disease	R-HSA-5655302	1.576572e-01	0.802	0	0
DCC mediated attractive signaling	R-HSA-418885	1.668342e-01	0.778	0	0
Signaling by NOTCH2	R-HSA-1980145	1.887065e-01	0.724	0	0
Smooth Muscle Contraction	R-HSA-445355	1.686202e-01	0.773	0	0
TBC/RABGAPs	R-HSA-8854214	1.786551e-01	0.748	0	0
Activation of NMDA receptors and postsynaptic events	R-HSA-442755	2.182390e-01	0.661	0	0
Oncogene Induced Senescence	R-HSA-2559585	2.013556e-01	0.696	0	0
Cyclin A/B1/B2 associated events during G2/M transition	R-HSA-69273	1.643274e-01	0.784	0	0
Generic Transcription Pathway	R-HSA-212436	1.772835e-01	0.751	1	0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	R-HSA-442729	1.953336e-01	0.709	0	0
Cell-cell junction organization	R-HSA-421270	1.544890e-01	0.811	0	0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	R-HSA-2173793	1.979963e-01	0.703	0	0
Activation of the TFAP2 (AP-2) family of transcription factors	R-HSA-8866907	2.221280e-01	0.653	0	0
Fibronectin matrix formation	R-HSA-1566977	2.035453e-01	0.691	0	0
Regulation of CDH1 Function	R-HSA-9764561	2.082092e-01	0.682	0	0
Regulation of TP53 Activity through Phosphorylation	R-HSA-6804756	1.697807e-01	0.770	1	1
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	R-HSA-8862803	1.831146e-01	0.737	1	1
Neurodegenerative Diseases	R-HSA-8863678	1.831146e-01	0.737	1	0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	R-HSA-6804115	1.547712e-01	0.810	0	0
SARS-CoV-2-host interactions	R-HSA-9705683	1.603123e-01	0.795	0	0
Regulation of MITF-M-dependent genes involved in pigmentation	R-HSA-9824585	2.007036e-01	0.697	0	0
Miscellaneous transport and binding events	R-HSA-5223345	1.763563e-01	0.754	0	0
SARS-CoV-1-host interactions	R-HSA-9692914	1.686212e-01	0.773	0	0
Interferon Signaling	R-HSA-913531	1.897722e-01	0.722	0	0
Signaling by TGFBR3	R-HSA-9839373	2.120852e-01	0.673	0	0
Interleukin-4 and Interleukin-13 signaling	R-HSA-6785807	1.572670e-01	0.803	0	0
Cytokine Signaling in Immune system	R-HSA-1280215	2.174637e-01	0.663	0	0
p130Cas linkage to MAPK signaling for integrins	R-HSA-372708	2.225484e-01	0.653	0	0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	R-HSA-5358606	2.225484e-01	0.653	0	0
Senescence-Associated Secretory Phenotype (SASP)	R-HSA-2559582	2.248247e-01	0.648	0	0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	R-HSA-2173796	2.274585e-01	0.643	0	0
Collagen chain trimerization	R-HSA-8948216	2.274585e-01	0.643	0	0
Processive synthesis on the C-strand of the telomere	R-HSA-174414	2.284125e-01	0.641	0	0
Tat-mediated HIV elongation arrest and recovery	R-HSA-167243	2.284125e-01	0.641	0	0
Pausing and recovery of Tat-mediated HIV elongation	R-HSA-167238	2.284125e-01	0.641	0	0
Mitochondrial unfolded protein response (UPRmt)	R-HSA-9841251	2.284125e-01	0.641	0	0
Interaction between L1 and Ankyrins	R-HSA-445095	2.284125e-01	0.641	0	0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	R-HSA-6803204	2.284125e-01	0.641	0	0
Defective Intrinsic Pathway for Apoptosis	R-HSA-9734009	2.284125e-01	0.641	1	0
Deadenylation-dependent mRNA decay	R-HSA-429914	2.292011e-01	0.640	0	0
Intraflagellar transport	R-HSA-5620924	2.354856e-01	0.628	0	0
tRNA processing	R-HSA-72306	2.381650e-01	0.623	0	0
PCNA-Dependent Long Patch Base Excision Repair	R-HSA-5651801	2.418821e-01	0.616	0	0
Serotonin Neurotransmitter Release Cycle	R-HSA-181429	2.418821e-01	0.616	0	0
Depolymerization of the Nuclear Lamina	R-HSA-4419969	2.418821e-01	0.616	0	0
Tie2 Signaling	R-HSA-210993	2.418821e-01	0.616	0	0
trans-Golgi Network Vesicle Budding	R-HSA-199992	2.422717e-01	0.616	0	0
Regulation of mRNA stability by proteins that bind AU-rich elements	R-HSA-450531	2.422717e-01	0.616	0	0
Activation of HOX genes during differentiation	R-HSA-5619507	2.424801e-01	0.615	0	0
Activation of anterior HOX genes in hindbrain development during early embryogenesis	R-HSA-5617472	2.424801e-01	0.615	0	0
RUNX3 regulates RUNX1-mediated transcription	R-HSA-8951911	2.555704e-01	0.592	0	0
Glycogen storage disease type XV (GYG1)	R-HSA-3814836	2.555704e-01	0.592	0	0
Glycogen storage disease type 0 (muscle GYS1)	R-HSA-3828062	2.555704e-01	0.592	0	0
Enhanced cleavage of VWF variant by ADAMTS13	R-HSA-9845619	2.555704e-01	0.592	0	0
Defective VWF cleavage by ADAMTS13 variant	R-HSA-9845621	2.555704e-01	0.592	0	0
TGFBR1 LBD Mutants in Cancer	R-HSA-3656535	2.555704e-01	0.592	0	0
Defective MMACHC causes MAHCC	R-HSA-3359474	3.085280e-01	0.511	0	0
MET activates PTPN11	R-HSA-8865999	3.085280e-01	0.511	0	0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome	R-HSA-9944997	3.085280e-01	0.511	0	0
Loss of Function of KMT2D in Kabuki Syndrome	R-HSA-9944971	3.085280e-01	0.511	0	0
HCN channels	R-HSA-1296061	3.577213e-01	0.446	0	0
Drug-mediated inhibition of CDK4/CDK6 activity	R-HSA-9754119	3.577213e-01	0.446	0	0
RUNX3 regulates BCL2L11 (BIM) transcription	R-HSA-8952158	3.577213e-01	0.446	0	0
Signaling by MAP2K mutants	R-HSA-9652169	3.577213e-01	0.446	0	0
GRB7 events in ERBB2 signaling	R-HSA-1306955	3.577213e-01	0.446	0	0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	R-HSA-69200	3.577213e-01	0.446	0	0
Establishment of Sister Chromatid Cohesion	R-HSA-2468052	2.491842e-01	0.603	0	0
Signaling by APC mutants	R-HSA-4839744	2.763294e-01	0.559	0	0
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	2.763294e-01	0.559	0	0
Truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	2.763294e-01	0.559	0	0
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	2.763294e-01	0.559	0	0
NFE2L2 regulating TCA cycle genes	R-HSA-9818025	4.034175e-01	0.394	0	0
NOSIP mediated eNOS trafficking	R-HSA-203754	4.034175e-01	0.394	0	0
Defective binding of VWF variant to GPIb:IX:V	R-HSA-9846298	4.034175e-01	0.394	0	0
Enhanced binding of GP1BA variant to VWF multimer:collagen	R-HSA-9845620	4.034175e-01	0.394	0	0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis	R-HSA-9623433	3.034143e-01	0.518	0	0
Condensation of Prometaphase Chromosomes	R-HSA-2514853	3.034143e-01	0.518	0	0
Signaling by GSK3beta mutants	R-HSA-5339716	3.034143e-01	0.518	0	0
APC/C:Cdc20 mediated degradation of Cyclin B	R-HSA-174048	2.614744e-01	0.583	0	0
Abortive elongation of HIV-1 transcript in the absence of Tat	R-HSA-167242	2.614744e-01	0.583	0	0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	R-HSA-9027276	3.303103e-01	0.481	0	0
Polymerase switching	R-HSA-69091	3.303103e-01	0.481	0	0
Leading Strand Synthesis	R-HSA-69109	3.303103e-01	0.481	0	0
Signaling by CTNNB1 phospho-site mutants	R-HSA-4839743	3.303103e-01	0.481	0	0
CTNNB1 S33 mutants aren't phosphorylated	R-HSA-5358747	3.303103e-01	0.481	0	0
CTNNB1 T41 mutants aren't phosphorylated	R-HSA-5358752	3.303103e-01	0.481	0	0
CTNNB1 S45 mutants aren't phosphorylated	R-HSA-5358751	3.303103e-01	0.481	0	0
CTNNB1 S37 mutants aren't phosphorylated	R-HSA-5358749	3.303103e-01	0.481	0	0
RUNX3 regulates CDKN1A transcription	R-HSA-8941855	4.458652e-01	0.351	0	0
Defects of platelet adhesion to exposed collagen	R-HSA-9823587	4.458652e-01	0.351	0	0
Nef Mediated CD8 Down-regulation	R-HSA-182218	4.458652e-01	0.351	0	0
Phosphorylation of Emi1	R-HSA-176417	4.458652e-01	0.351	0	0
Noncanonical activation of NOTCH3	R-HSA-9017802	4.458652e-01	0.351	0	0
IkBA variant leads to EDA-ID	R-HSA-5603029	4.458652e-01	0.351	0	0
SLIT2:ROBO1 increases RHOA activity	R-HSA-8985586	4.458652e-01	0.351	0	0
Loss of MECP2 binding ability to the NCoR/SMRT complex	R-HSA-9022537	4.458652e-01	0.351	0	0
HIV elongation arrest and recovery	R-HSA-167287	2.440994e-01	0.612	0	0
Pausing and recovery of HIV elongation	R-HSA-167290	2.440994e-01	0.612	0	0
Signaling by Erythropoietin	R-HSA-9006335	2.600165e-01	0.585	0	0
Developmental Lineage of Mammary Gland Myoepithelial Cells	R-HSA-9927432	2.600165e-01	0.585	0	0
Signaling by LTK in cancer	R-HSA-9842640	4.852950e-01	0.314	0	0
Erythropoietin activates STAT5	R-HSA-9027283	4.852950e-01	0.314	0	0
Autointegration results in viral DNA circles	R-HSA-177539	4.852950e-01	0.314	0	0
RAS signaling downstream of NF1 loss-of-function variants	R-HSA-6802953	4.852950e-01	0.314	0	0
FGFR2 alternative splicing	R-HSA-6803529	3.411163e-01	0.467	0	0
Sema3A PAK dependent Axon repulsion	R-HSA-399954	4.088450e-01	0.388	0	0
Beta-catenin phosphorylation cascade	R-HSA-196299	4.088450e-01	0.388	0	0
RNA Pol II CTD phosphorylation and interaction with CE	R-HSA-77075	3.610507e-01	0.442	0	0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	R-HSA-167160	3.610507e-01	0.442	0	0
HSF1-dependent transactivation	R-HSA-3371571	2.719395e-01	0.566	0	0
Formation of RNA Pol II elongation complex	R-HSA-112382	2.843868e-01	0.546	0	0
RNA Polymerase II Transcription Elongation	R-HSA-75955	2.969549e-01	0.527	0	0
BMAL1:CLOCK,NPAS2 activates circadian expression	R-HSA-1368108	3.583262e-01	0.446	0	0
HDACs deacetylate histones	R-HSA-3214815	3.223889e-01	0.492	0	0
Gap-filling DNA repair synthesis and ligation in TC-NER	R-HSA-6782210	3.352227e-01	0.475	0	0
Nuclear Receptor transcription pathway	R-HSA-383280	3.044223e-01	0.517	0	0
G1/S-Specific Transcription	R-HSA-69205	3.913663e-01	0.407	0	0
AUF1 (hnRNP D0) binds and destabilizes mRNA	R-HSA-450408	3.913663e-01	0.407	0	0
Removal of the Flap Intermediate from the C-strand	R-HSA-174437	4.826195e-01	0.316	0	0
Formation of the HIV-1 Early Elongation Complex	R-HSA-167158	4.584652e-01	0.339	0	0
Formation of the Early Elongation Complex	R-HSA-113418	4.584652e-01	0.339	0	0
Impaired BRCA2 binding to RAD51	R-HSA-9709570	4.772341e-01	0.321	0	0
Attenuation phase	R-HSA-3371568	4.564708e-01	0.341	0	0
Inhibition of DNA recombination at telomere	R-HSA-9670095	4.564708e-01	0.341	0	0
Formation of HIV elongation complex in the absence of HIV Tat	R-HSA-167152	4.564708e-01	0.341	0	0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	R-HSA-174178	4.681296e-01	0.330	0	0
PPARA activates gene expression	R-HSA-1989781	4.007864e-01	0.397	0	0
Nuclear events mediated by NFE2L2	R-HSA-9759194	4.118883e-01	0.385	0	0
Regulation of lipid metabolism by PPARalpha	R-HSA-400206	3.151722e-01	0.501	0	0
HIV Transcription Elongation	R-HSA-167169	4.564708e-01	0.341	0	0
RNA Polymerase III Transcription Initiation	R-HSA-76046	2.761263e-01	0.559	0	0
EPH-Ephrin signaling	R-HSA-2682334	3.412684e-01	0.467	0	0
mRNA Capping	R-HSA-72086	4.772341e-01	0.321	0	0
Termination of translesion DNA synthesis	R-HSA-5656169	4.772341e-01	0.321	0	0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	R-HSA-9843970	3.583262e-01	0.446	0	0
Tat-mediated elongation of the HIV-1 transcript	R-HSA-167246	4.564708e-01	0.341	0	0
DNA Damage Bypass	R-HSA-73893	4.112504e-01	0.386	0	0
Nephrin family interactions	R-HSA-373753	2.812567e-01	0.551	0	0
Meiotic synapsis	R-HSA-1221632	4.681296e-01	0.330	0	0
Developmental Cell Lineages	R-HSA-9734767	3.486811e-01	0.458	0	0
PI3K/AKT activation	R-HSA-198203	2.491842e-01	0.603	0	0
Formation of HIV-1 elongation complex containing HIV-1 Tat	R-HSA-167200	4.403781e-01	0.356	0	0
Formation of Incision Complex in GG-NER	R-HSA-5696395	4.564708e-01	0.341	0	0
Signaling by CSF1 (M-CSF) in myeloid cells	R-HSA-9680350	3.583262e-01	0.446	0	0
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	3.824394e-01	0.417	0	0
TFAP2 (AP-2) family regulates transcription of cell cycle factors	R-HSA-8866911	3.577213e-01	0.446	0	0
Regulation of gap junction activity	R-HSA-191650	3.577213e-01	0.446	0	0
RUNX1 regulates transcription of genes involved in BCR signaling	R-HSA-8939245	4.034175e-01	0.394	0	0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK	R-HSA-9931529	4.034175e-01	0.394	1	1
NF-kB is activated and signals survival	R-HSA-209560	3.034143e-01	0.518	0	0
E2F mediated regulation of DNA replication	R-HSA-113510	2.614744e-01	0.583	0	0
VLDLR internalisation and degradation	R-HSA-8866427	3.303103e-01	0.481	0	0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	R-HSA-427389	2.682733e-01	0.571	0	0
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	4.724611e-01	0.326	0	0
G1/S Transition	R-HSA-69206	3.407894e-01	0.468	0	0
ESR-mediated signaling	R-HSA-8939211	2.701062e-01	0.568	0	0
Telomere C-strand (Lagging Strand) Synthesis	R-HSA-174417	2.963155e-01	0.528	0	0
RNA Polymerase I Transcription	R-HSA-73864	4.490266e-01	0.348	0	0
Synthesis of DNA	R-HSA-69239	2.676540e-01	0.572	0	0
MET activates RAS signaling	R-HSA-8851805	3.303103e-01	0.481	0	0
RNA Polymerase I Promoter Clearance	R-HSA-73854	4.254057e-01	0.371	0	0
Resolution of AP sites via the single-nucleotide replacement pathway	R-HSA-110381	4.034175e-01	0.394	0	0
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	3.831117e-01	0.417	0	0
Activation of ATR in response to replication stress	R-HSA-176187	3.252521e-01	0.488	0	0
mRNA decay by 5' to 3' exoribonuclease	R-HSA-430039	4.586476e-01	0.339	0	0
Chromatin modifications during the maternal to zygotic transition (MZT)	R-HSA-9821002	4.724050e-01	0.326	0	0
Telomere Maintenance	R-HSA-157579	2.789468e-01	0.554	0	0
Signaling by SCF-KIT	R-HSA-1433557	3.248079e-01	0.488	0	0
Collagen formation	R-HSA-1474290	3.617093e-01	0.442	0	0
WNT5A-dependent internalization of FZD4	R-HSA-5099900	4.340415e-01	0.362	0	0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	R-HSA-164938	4.826195e-01	0.316	0	0
Elevation of cytosolic Ca2+ levels	R-HSA-139853	4.826195e-01	0.316	0	0
DNA Replication Pre-Initiation	R-HSA-69002	2.848885e-01	0.545	0	0
Regulation of gene expression by Hypoxia-inducible Factor	R-HSA-1234158	3.034143e-01	0.518	0	0
Sema4D induced cell migration and growth-cone collapse	R-HSA-416572	2.812567e-01	0.551	0	0
p75NTR signals via NF-kB	R-HSA-193639	4.088450e-01	0.388	0	0
Extension of Telomeres	R-HSA-180786	3.740053e-01	0.427	0	0
Activation of gene expression by SREBF (SREBP)	R-HSA-2426168	2.731270e-01	0.564	0	0
Interleukin-33 signaling	R-HSA-9014843	2.555704e-01	0.592	0	0
Signalling to ERK5	R-HSA-198765	2.555704e-01	0.592	0	0
Loss of MECP2 binding ability to 5mC-DNA	R-HSA-9022538	3.085280e-01	0.511	0	0
SARS-CoV-2 targets PDZ proteins in cell-cell junction	R-HSA-9705677	3.577213e-01	0.446	0	0
Loss of Function of TGFBR1 in Cancer	R-HSA-3656534	4.034175e-01	0.394	0	0
Signaling by AMER1 mutants	R-HSA-4839748	3.034143e-01	0.518	0	0
Synthesis of PS	R-HSA-1483101	4.458652e-01	0.351	0	0
Regulation of CDH1 mRNA translation by microRNAs	R-HSA-9764562	3.831117e-01	0.417	0	0
G2/M DNA replication checkpoint	R-HSA-69478	4.852950e-01	0.314	0	0
Nuclear signaling by ERBB4	R-HSA-1251985	2.682733e-01	0.571	0	0
Association of TriC/CCT with target proteins during biosynthesis	R-HSA-390471	3.417784e-01	0.466	0	0
MAP kinase activation	R-HSA-450294	3.999452e-01	0.398	0	0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	R-HSA-110373	4.201119e-01	0.377	0	0
Regulation of cholesterol biosynthesis by SREBP (SREBF)	R-HSA-1655829	3.151242e-01	0.502	0	0
Oxidative Stress Induced Senescence	R-HSA-2559580	3.256161e-01	0.487	0	0
Signaling by WNT	R-HSA-195721	3.254480e-01	0.488	0	0
Differentiation of T cells	R-HSA-9945266	4.340415e-01	0.362	0	0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)	R-HSA-9942503	4.340415e-01	0.362	0	0
Transport to the Golgi and subsequent modification	R-HSA-948021	2.823558e-01	0.549	0	0
Activation of NOXA and translocation to mitochondria	R-HSA-111448	3.577213e-01	0.446	0	0
Loss of function of MECP2 in Rett syndrome	R-HSA-9005891	3.303103e-01	0.481	0	0
Disorders of Nervous System Development	R-HSA-9697154	3.303103e-01	0.481	0	0
Pervasive developmental disorders	R-HSA-9005895	3.303103e-01	0.481	0	0
Dopamine Neurotransmitter Release Cycle	R-HSA-212676	3.411163e-01	0.467	0	0
Switching of origins to a post-replicative state	R-HSA-69052	3.897970e-01	0.409	0	0
Constitutive Signaling by EGFRvIII	R-HSA-5637810	4.826195e-01	0.316	0	0
Signaling by EGFRvIII in Cancer	R-HSA-5637812	4.826195e-01	0.316	0	0
Base Excision Repair	R-HSA-73884	4.465844e-01	0.350	0	0
Constitutive Signaling by Overexpressed ERBB2	R-HSA-9634285	3.303103e-01	0.481	0	0
Acyl chain remodelling of PS	R-HSA-1482801	4.005915e-01	0.397	0	0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	R-HSA-6804114	4.586476e-01	0.339	0	0
Signaling by ERBB2	R-HSA-1227986	3.869764e-01	0.412	0	0
Diseases of Mismatch Repair (MMR)	R-HSA-5423599	3.085280e-01	0.511	0	0
Sensory perception of sour taste	R-HSA-9729555	3.577213e-01	0.446	0	0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	R-HSA-428359	2.491842e-01	0.603	0	0
Interleukin-36 pathway	R-HSA-9014826	4.034175e-01	0.394	0	0
Signalling to p38 via RIT and RIN	R-HSA-187706	4.458652e-01	0.351	0	0
Signaling by FGFR4 in disease	R-HSA-5655291	3.831117e-01	0.417	0	0
Integration of viral DNA into host genomic DNA	R-HSA-175567	4.852950e-01	0.314	0	0
Interleukin receptor SHC signaling	R-HSA-912526	3.610507e-01	0.442	0	0
Receptor-type tyrosine-protein phosphatases	R-HSA-388844	4.340415e-01	0.362	0	0
Laminin interactions	R-HSA-3000157	4.005915e-01	0.397	0	0
Signaling by FGFR in disease	R-HSA-1226099	2.625332e-01	0.581	0	0
FGFR1 mutant receptor activation	R-HSA-1839124	3.252521e-01	0.488	0	0
EGFR downregulation	R-HSA-182971	2.923923e-01	0.534	0	0
HCMV Late Events	R-HSA-9610379	4.170771e-01	0.380	0	0
Downstream signal transduction	R-HSA-186763	2.923923e-01	0.534	0	0
Sema4D in semaphorin signaling	R-HSA-400685	4.005915e-01	0.397	0	0
Mitochondrial biogenesis	R-HSA-1592230	2.651822e-01	0.576	0	0
The role of GTSE1 in G2/M progression after G2 checkpoint	R-HSA-8852276	2.619324e-01	0.582	0	0
Ion homeostasis	R-HSA-5578775	3.352227e-01	0.475	0	0
Collagen degradation	R-HSA-1442490	3.999452e-01	0.398	0	0
PECAM1 interactions	R-HSA-210990	2.763294e-01	0.559	0	0
Suppression of apoptosis	R-HSA-9635465	2.763294e-01	0.559	0	0
Ovarian tumor domain proteases	R-HSA-5689896	4.078024e-01	0.390	0	0
PI3K/AKT Signaling in Cancer	R-HSA-2219528	3.841227e-01	0.416	0	0
Signaling by ROBO receptors	R-HSA-376176	4.717518e-01	0.326	0	0
Muscle contraction	R-HSA-397014	4.472065e-01	0.349	0	0
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis	R-HSA-9708296	2.555704e-01	0.592	0	0
The NLRP1 inflammasome	R-HSA-844455	3.085280e-01	0.511	0	0
Regulation of HMOX1 expression and activity	R-HSA-9707587	3.577213e-01	0.446	0	0
CLEC7A/inflammasome pathway	R-HSA-5660668	4.458652e-01	0.351	0	0
CREB phosphorylation	R-HSA-199920	4.852950e-01	0.314	0	0
NADPH regeneration	R-HSA-389542	4.852950e-01	0.314	0	0
Synthesis of IP3 and IP4 in the cytosol	R-HSA-1855204	3.252521e-01	0.488	0	0
Negative regulation of FLT3	R-HSA-9706369	4.340415e-01	0.362	0	0
FLT3 signaling in disease	R-HSA-9682385	3.913663e-01	0.407	0	0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	R-HSA-9725554	4.403781e-01	0.356	0	0
Potential therapeutics for SARS	R-HSA-9679191	3.603286e-01	0.443	0	0
VEGFA-VEGFR2 Pathway	R-HSA-4420097	3.565288e-01	0.448	0	0
Zygotic genome activation (ZGA)	R-HSA-9819196	3.011644e-01	0.521	0	0
CaMK IV-mediated phosphorylation of CREB	R-HSA-111932	2.491842e-01	0.603	0	0
MECP2 regulates neuronal receptors and channels	R-HSA-9022699	4.201119e-01	0.377	0	0
Signaling by Non-Receptor Tyrosine Kinases	R-HSA-9006927	4.258205e-01	0.371	0	0
Signaling by PTK6	R-HSA-8848021	4.258205e-01	0.371	0	0
Signaling by PDGF	R-HSA-186797	4.128977e-01	0.384	0	0
Signaling by VEGF	R-HSA-194138	4.581657e-01	0.339	0	0
Pre-NOTCH Transcription and Translation	R-HSA-1912408	4.575238e-01	0.340	0	0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	R-HSA-6803205	3.411163e-01	0.467	0	0
Cyclin A:Cdk2-associated events at S phase entry	R-HSA-69656	3.779218e-01	0.423	0	0
Netrin-1 signaling	R-HSA-373752	3.391669e-01	0.470	0	0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	R-HSA-3134963	4.034175e-01	0.394	0	0
Epithelial-Mesenchymal Transition (EMT) during gastrulation	R-HSA-9758919	4.458652e-01	0.351	0	0
Regulation of TP53 Activity through Association with Co-factors	R-HSA-6804759	3.569072e-01	0.447	0	0
Regulation of MITF-M-dependent genes involved in apoptosis	R-HSA-9824594	3.011644e-01	0.521	0	0
Signaling by TGF-beta Receptor Complex	R-HSA-170834	4.029295e-01	0.395	0	0
Josephin domain DUBs	R-HSA-5689877	2.491842e-01	0.603	0	0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	R-HSA-8866910	4.586476e-01	0.339	0	0
Synthesis of PIPs at the plasma membrane	R-HSA-1660499	4.128977e-01	0.384	0	0
Signaling by TGF-beta Receptor Complex in Cancer	R-HSA-3304351	4.852950e-01	0.314	0	0
Influenza Infection	R-HSA-168255	2.979325e-01	0.526	0	0
OAS antiviral response	R-HSA-8983711	3.303103e-01	0.481	0	0
Signaling by Interleukins	R-HSA-449147	2.798598e-01	0.553	0	0
Signaling by Leptin	R-HSA-2586552	2.491842e-01	0.603	0	0
Specification of primordial germ cells	R-HSA-9827857	4.826195e-01	0.316	0	0
SARS-CoV Infections	R-HSA-9679506	3.126693e-01	0.505	0	0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	R-HSA-8950505	4.515260e-01	0.345	0	0
Interleukin-7 signaling	R-HSA-1266695	4.005915e-01	0.397	0	0
Collagen biosynthesis and modifying enzymes	R-HSA-1650814	4.895540e-01	0.310	0	0
Assembly of the pre-replicative complex	R-HSA-68867	4.900677e-01	0.310	0	0
DNA Replication	R-HSA-69306	4.944429e-01	0.306	0	0
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	4.956940e-01	0.305	0	0
Signaling by ERBB2 in Cancer	R-HSA-1227990	4.956940e-01	0.305	0	0
Regulation of actin dynamics for phagocytic cup formation	R-HSA-2029482	4.989853e-01	0.302	0	0
Rab regulation of trafficking	R-HSA-9007101	4.998114e-01	0.301	0	0
GAB1 signalosome	R-HSA-180292	5.059232e-01	0.296	0	0
Ephrin signaling	R-HSA-3928664	5.059232e-01	0.296	0	0
Trafficking of GluR2-containing AMPA receptors	R-HSA-416993	5.059232e-01	0.296	0	0
Chaperone Mediated Autophagy	R-HSA-9613829	5.059232e-01	0.296	0	0
Signaling by ERBB2 ECD mutants	R-HSA-9665348	5.059232e-01	0.296	0	0
Regulation of TP53 Activity through Methylation	R-HSA-6804760	5.059232e-01	0.296	0	0
Polo-like kinase mediated events	R-HSA-156711	5.059232e-01	0.296	0	0
Nephron development	R-HSA-9831926	5.059232e-01	0.296	0	0
Cytoprotection by HMOX1	R-HSA-9707564	5.071063e-01	0.295	0	0
Trafficking of AMPA receptors	R-HSA-399719	5.138213e-01	0.289	0	0
Cargo concentration in the ER	R-HSA-5694530	5.138213e-01	0.289	0	0
Evasion by RSV of host interferon responses	R-HSA-9833109	5.138213e-01	0.289	0	0
Interleukin-17 signaling	R-HSA-448424	5.144252e-01	0.289	0	0
MET activates PI3K/AKT signaling	R-HSA-8851907	5.219213e-01	0.282	0	0
RUNX3 Regulates Immune Response and Cell Migration	R-HSA-8949275	5.219213e-01	0.282	0	0
IFNG signaling activates MAPKs	R-HSA-9732724	5.219213e-01	0.282	0	0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake	R-HSA-9031525	5.219213e-01	0.282	0	0
Cohesin Loading onto Chromatin	R-HSA-2470946	5.219213e-01	0.282	0	0
Recycling of eIF2:GDP	R-HSA-72731	5.219213e-01	0.282	0	0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose	R-HSA-9031528	5.219213e-01	0.282	0	0
Disinhibition of SNARE formation	R-HSA-114516	5.219213e-01	0.282	0	0
PTK6 Expression	R-HSA-8849473	5.219213e-01	0.282	0	0
Nef Mediated CD4 Down-regulation	R-HSA-167590	5.219213e-01	0.282	0	0
Activated NTRK3 signals through PI3K	R-HSA-9603381	5.219213e-01	0.282	0	0
VLDL clearance	R-HSA-8964046	5.219213e-01	0.282	0	0
Regulation of PTEN localization	R-HSA-8948747	5.219213e-01	0.282	0	0
CHL1 interactions	R-HSA-447041	5.219213e-01	0.282	0	0
Regulation of mitotic cell cycle	R-HSA-453276	5.266870e-01	0.278	0	0
APC/C-mediated degradation of cell cycle proteins	R-HSA-174143	5.266870e-01	0.278	0	0
NoRC negatively regulates rRNA expression	R-HSA-427413	5.266870e-01	0.278	0	0
Crosslinking of collagen fibrils	R-HSA-2243919	5.285322e-01	0.277	0	0
Signaling by FGFR2 IIIa TM	R-HSA-8851708	5.285322e-01	0.277	0	0
Meiosis	R-HSA-1500620	5.297700e-01	0.276	0	0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells	R-HSA-9937080	5.315950e-01	0.274	0	0
Signaling by WNT in cancer	R-HSA-4791275	5.315950e-01	0.274	0	0
RMTs methylate histone arginines	R-HSA-3214858	5.341884e-01	0.272	0	0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	R-HSA-72662	5.365765e-01	0.270	0	0
SARS-CoV-2 Infection	R-HSA-9694516	5.436679e-01	0.265	0	0
Regulation of PD-L1(CD274) expression	R-HSA-9909648	5.458553e-01	0.263	0	0
Viral Infection Pathways	R-HSA-9824446	5.472500e-01	0.262	0	0
PIP3 activates AKT signaling	R-HSA-1257604	5.484505e-01	0.261	0	0
HDR through Single Strand Annealing (SSA)	R-HSA-5685938	5.489972e-01	0.260	0	0
Glutamate binding, activation of AMPA receptors and synaptic plasticity	R-HSA-399721	5.489972e-01	0.260	0	0
Regulation of MECP2 expression and activity	R-HSA-9022692	5.489972e-01	0.260	0	0
Deposition of new CENPA-containing nucleosomes at the centromere	R-HSA-606279	5.490674e-01	0.260	0	0
Nucleosome assembly	R-HSA-774815	5.490674e-01	0.260	0	0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	R-HSA-5693565	5.497851e-01	0.260	0	0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	R-HSA-9609523	5.504276e-01	0.259	0	0
Formation of definitive endoderm	R-HSA-9823730	5.504276e-01	0.259	0	0
Signal transduction by L1	R-HSA-445144	5.504276e-01	0.259	0	0
Signaling by TGFB family members	R-HSA-9006936	5.520118e-01	0.258	0	0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	R-HSA-77588	5.559433e-01	0.255	0	0
Activation of RAS in B cells	R-HSA-1169092	5.559433e-01	0.255	0	0
Activated NTRK2 signals through PI3K	R-HSA-9028335	5.559433e-01	0.255	0	0
Myoclonic epilepsy of Lafora	R-HSA-3785653	5.559433e-01	0.255	0	0
Nef mediated downregulation of MHC class I complex cell surface expression	R-HSA-164940	5.559433e-01	0.255	0	0
Formyl peptide receptors bind formyl peptides and many other ligands	R-HSA-444473	5.559433e-01	0.255	0	0
Axonal growth inhibition (RHOA activation)	R-HSA-193634	5.559433e-01	0.255	0	0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	R-HSA-8939246	5.559433e-01	0.255	0	0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	R-HSA-8849469	5.559433e-01	0.255	0	0
Sodium/Proton exchangers	R-HSA-425986	5.559433e-01	0.255	0	0
Signaling by ERBB4	R-HSA-1236394	5.626738e-01	0.250	0	0
Condensation of Prophase Chromosomes	R-HSA-2299718	5.636933e-01	0.249	0	0
Autodegradation of Cdh1 by Cdh1:APC/C	R-HSA-174084	5.636933e-01	0.249	0	0
Diseases of DNA repair	R-HSA-9675135	5.636933e-01	0.249	0	0
NFE2L2 regulating anti-oxidant/detoxification enzymes	R-HSA-9818027	5.660127e-01	0.247	0	0
Effects of PIP2 hydrolysis	R-HSA-114508	5.660127e-01	0.247	0	0
EGR2 and SOX10-mediated initiation of Schwann cell myelination	R-HSA-9619665	5.660127e-01	0.247	0	0
SARS-CoV-1 Infection	R-HSA-9678108	5.690811e-01	0.245	0	0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	R-HSA-450321	5.715962e-01	0.243	0	0
Signaling by Ligand-Responsive EGFR Variants in Cancer	R-HSA-5637815	5.715962e-01	0.243	0	0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	R-HSA-1236382	5.715962e-01	0.243	0	0
Signalling to RAS	R-HSA-167044	5.715962e-01	0.243	0	0
Early Phase of HIV Life Cycle	R-HSA-162594	5.715962e-01	0.243	0	0
Diseases of programmed cell death	R-HSA-9645723	5.738000e-01	0.241	1	0
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	R-HSA-6781827	5.743776e-01	0.241	0	0
TP53 Regulates Transcription of Cell Death Genes	R-HSA-5633008	5.743776e-01	0.241	0	0
Gastrulation	R-HSA-9758941	5.752833e-01	0.240	0	0
IRS-related events triggered by IGF1R	R-HSA-2428928	5.756401e-01	0.240	0	0
Formation of paraxial mesoderm	R-HSA-9793380	5.756401e-01	0.240	0	0
Intracellular signaling by second messengers	R-HSA-9006925	5.817476e-01	0.235	0	0
Dual Incision in GG-NER	R-HSA-5696400	5.826285e-01	0.235	0	0
Diseases of DNA Double-Strand Break Repair	R-HSA-9675136	5.826285e-01	0.235	0	0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function	R-HSA-9701190	5.826285e-01	0.235	0	0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	R-HSA-110328	5.826285e-01	0.235	0	0
Interleukin-12 signaling	R-HSA-9020591	5.859239e-01	0.232	0	0
Lipophagy	R-HSA-9613354	5.875461e-01	0.231	0	0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	R-HSA-5649702	5.875461e-01	0.231	0	0
Activation of the AP-1 family of transcription factors	R-HSA-450341	5.875461e-01	0.231	0	0
p75NTR regulates axonogenesis	R-HSA-193697	5.875461e-01	0.231	0	0
Regulation of signaling by NODAL	R-HSA-1433617	5.875461e-01	0.231	0	0
AKT phosphorylates targets in the nucleus	R-HSA-198693	5.875461e-01	0.231	0	0
Regulation of CDH11 gene transcription	R-HSA-9762293	5.875461e-01	0.231	0	0
Regulated proteolysis of p75NTR	R-HSA-193692	5.875461e-01	0.231	0	0
Interleukin-1 processing	R-HSA-448706	5.875461e-01	0.231	0	0
NOTCH4 Activation and Transmission of Signal to the Nucleus	R-HSA-9013700	5.875461e-01	0.231	0	0
Cellular response to mitochondrial stress	R-HSA-9840373	5.875461e-01	0.231	0	0
Butyrophilin (BTN) family interactions	R-HSA-8851680	5.875461e-01	0.231	0	0
Regulation of APC/C activators between G1/S and early anaphase	R-HSA-176408	5.882698e-01	0.230	0	0
RNA Polymerase III Transcription Initiation From Type 2 Promoter	R-HSA-76066	5.920308e-01	0.228	0	0
Signaling by NTRK3 (TRKC)	R-HSA-9034015	5.920308e-01	0.228	0	0
FOXO-mediated transcription of cell cycle genes	R-HSA-9617828	5.920308e-01	0.228	0	0
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-5693616	5.988343e-01	0.223	0	0
TP53 Regulates Metabolic Genes	R-HSA-5628897	6.018671e-01	0.220	0	0
DNA Repair	R-HSA-73894	6.045662e-01	0.219	0	0
SLC transporter disorders	R-HSA-5619102	6.070815e-01	0.217	0	0
Parasite infection	R-HSA-9664407	6.084244e-01	0.216	0	0
FCGR3A-mediated phagocytosis	R-HSA-9664422	6.084244e-01	0.216	0	0
Leishmania phagocytosis	R-HSA-9664417	6.084244e-01	0.216	0	0
MAPK family signaling cascades	R-HSA-5683057	6.094410e-01	0.215	0	0
RNA Polymerase III Transcription Initiation From Type 3 Promoter	R-HSA-76071	6.117285e-01	0.213	0	0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	R-HSA-9670439	6.117285e-01	0.213	0	0
RNA Polymerase III Transcription Initiation From Type 1 Promoter	R-HSA-76061	6.117285e-01	0.213	0	0
Signaling by KIT in disease	R-HSA-9669938	6.117285e-01	0.213	0	0
LDL clearance	R-HSA-8964038	6.117285e-01	0.213	0	0
IGF1R signaling cascade	R-HSA-2428924	6.128974e-01	0.213	0	0
Calmodulin induced events	R-HSA-111933	6.146217e-01	0.211	0	0
CaM pathway	R-HSA-111997	6.146217e-01	0.211	0	0
MAPK3 (ERK1) activation	R-HSA-110056	6.169016e-01	0.210	0	0
Erythropoietin activates Phospholipase C gamma (PLCG)	R-HSA-9027277	6.169016e-01	0.210	0	0
DNA replication initiation	R-HSA-68952	6.169016e-01	0.210	0	0
Folding of actin by CCT/TriC	R-HSA-390450	6.169016e-01	0.210	0	0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	R-HSA-5140745	6.169016e-01	0.210	0	0
Formation of intermediate mesoderm	R-HSA-9761174	6.169016e-01	0.210	0	0
EGFR Transactivation by Gastrin	R-HSA-2179392	6.169016e-01	0.210	0	0
2-LTR circle formation	R-HSA-164843	6.169016e-01	0.210	0	0
Pexophagy	R-HSA-9664873	6.169016e-01	0.210	0	0
Receptor Mediated Mitophagy	R-HSA-8934903	6.169016e-01	0.210	0	0
MECP2 regulates transcription of neuronal ligands	R-HSA-9022702	6.169016e-01	0.210	0	0
Regulation of CDH11 function	R-HSA-9762292	6.169016e-01	0.210	0	0
Signaling by FGFR2 in disease	R-HSA-5655253	6.194676e-01	0.208	0	0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	6.248832e-01	0.204	0	0
TRAF6 mediated IRF7 activation	R-HSA-933541	6.299844e-01	0.201	0	0
Signaling by FGFR2	R-HSA-5654738	6.304210e-01	0.200	0	0
Response of EIF2AK1 (HRI) to heme deficiency	R-HSA-9648895	6.306908e-01	0.200	0	0
The role of Nef in HIV-1 replication and disease pathogenesis	R-HSA-164952	6.306908e-01	0.200	0	0
Syndecan interactions	R-HSA-3000170	6.306908e-01	0.200	0	0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	R-HSA-9634638	6.306908e-01	0.200	0	0
Growth hormone receptor signaling	R-HSA-982772	6.306908e-01	0.200	0	0
Homology Directed Repair	R-HSA-5693538	6.378048e-01	0.195	0	0
Processing of DNA double-strand break ends	R-HSA-5693607	6.410988e-01	0.193	0	0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	R-HSA-933543	6.441693e-01	0.191	0	0
Activated NTRK3 signals through RAS	R-HSA-9034864	6.441693e-01	0.191	0	0
Homologous DNA Pairing and Strand Exchange	R-HSA-5693579	6.449180e-01	0.190	0	0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	R-HSA-174184	6.456128e-01	0.190	0	0
E3 ubiquitin ligases ubiquitinate target proteins	R-HSA-8866654	6.456128e-01	0.190	0	0
SARS-CoV-1 activates/modulates innate immune responses	R-HSA-9692916	6.456128e-01	0.190	0	0
Uptake and actions of bacterial toxins	R-HSA-5339562	6.456128e-01	0.190	0	0
Transcriptional regulation by RUNX2	R-HSA-8878166	6.465068e-01	0.189	0	0
DNA Double Strand Break Response	R-HSA-5693606	6.481736e-01	0.188	0	0
HDR through Homologous Recombination (HRR)	R-HSA-5685942	6.481736e-01	0.188	0	0
TRAF6 mediated NF-kB activation	R-HSA-933542	6.489224e-01	0.188	0	0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	R-HSA-179419	6.582315e-01	0.182	0	0
Plasma lipoprotein clearance	R-HSA-8964043	6.594198e-01	0.181	0	0
Fcgamma receptor (FCGR) dependent phagocytosis	R-HSA-2029480	6.658972e-01	0.177	0	0
Polymerase switching on the C-strand of the telomere	R-HSA-174411	6.664314e-01	0.176	0	0
Synthesis of PIPs at the early endosome membrane	R-HSA-1660516	6.664314e-01	0.176	0	0
Integration of provirus	R-HSA-162592	6.694978e-01	0.174	0	0
Activated NTRK2 signals through RAS	R-HSA-9026519	6.694978e-01	0.174	0	0
Mitotic Telophase/Cytokinesis	R-HSA-68884	6.694978e-01	0.174	0	0
APOBEC3G mediated resistance to HIV-1 infection	R-HSA-180689	6.694978e-01	0.174	0	0
POLB-Dependent Long Patch Base Excision Repair	R-HSA-110362	6.694978e-01	0.174	0	0
Translation initiation complex formation	R-HSA-72649	6.705434e-01	0.174	0	0
Base-Excision Repair, AP Site Formation	R-HSA-73929	6.705434e-01	0.174	0	0
CDK-mediated phosphorylation and removal of Cdc6	R-HSA-69017	6.705434e-01	0.174	0	0
RUNX1 regulates transcription of genes involved in differentiation of HSCs	R-HSA-8939236	6.720005e-01	0.173	0	0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	R-HSA-9844594	6.734885e-01	0.172	0	0
Transcriptional regulation of brown and beige adipocyte differentiation	R-HSA-9843743	6.734885e-01	0.172	0	0
Generation of second messenger molecules	R-HSA-202433	6.734885e-01	0.172	0	0
Interleukin-2 family signaling	R-HSA-451927	6.734885e-01	0.172	0	0
RAF/MAP kinase cascade	R-HSA-5673001	6.769916e-01	0.169	0	0
Regulation of endogenous retroelements by KRAB-ZFP proteins	R-HSA-9843940	6.813508e-01	0.167	0	0
COPII-mediated vesicle transport	R-HSA-204005	6.813508e-01	0.167	0	0
Cyclin E associated events during G1/S transition	R-HSA-69202	6.813508e-01	0.167	0	0
APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176409	6.825462e-01	0.166	0	0
Signaling by EGFR in Cancer	R-HSA-1643713	6.832282e-01	0.165	0	0
Synthesis of PIPs at the Golgi membrane	R-HSA-1660514	6.832282e-01	0.165	0	0
Regulation of RUNX1 Expression and Activity	R-HSA-8934593	6.832282e-01	0.165	0	0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	6.871245e-01	0.163	0	0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	6.871245e-01	0.163	0	0
FLT3 Signaling	R-HSA-9607240	6.871245e-01	0.163	0	0
GRB2 events in EGFR signaling	R-HSA-179812	6.930247e-01	0.159	0	0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex	R-HSA-9931530	6.930247e-01	0.159	1	1
p75NTR recruits signalling complexes	R-HSA-209543	6.930247e-01	0.159	0	0
SHC-related events triggered by IGF1R	R-HSA-2428933	6.930247e-01	0.159	0	0
Activated NTRK2 signals through FRS2 and FRS3	R-HSA-9028731	6.930247e-01	0.159	0	0
Advanced glycosylation endproduct receptor signaling	R-HSA-879415	6.930247e-01	0.159	0	0
Role of second messengers in netrin-1 signaling	R-HSA-418890	6.930247e-01	0.159	0	0
Reversal of alkylation damage by DNA dioxygenases	R-HSA-73943	6.930247e-01	0.159	0	0
Interleukin-15 signaling	R-HSA-8983432	6.930247e-01	0.159	0	0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176814	6.942386e-01	0.158	0	0
Ribosomal scanning and start codon recognition	R-HSA-72702	6.942386e-01	0.158	0	0
EPHA-mediated growth cone collapse	R-HSA-3928663	6.993255e-01	0.155	0	0
Disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	6.993255e-01	0.155	0	0
RNA Polymerase I Transcription Termination	R-HSA-73863	6.993255e-01	0.155	0	0
Signaling by FGFR3 in disease	R-HSA-5655332	6.993255e-01	0.155	0	0
Signaling by NTRK2 (TRKB)	R-HSA-9006115	6.993255e-01	0.155	1	0
Insulin processing	R-HSA-264876	6.993255e-01	0.155	0	0
KEAP1-NFE2L2 pathway	R-HSA-9755511	7.011076e-01	0.154	0	0
XBP1(S) activates chaperone genes	R-HSA-381038	7.011500e-01	0.154	0	0
Pre-NOTCH Expression and Processing	R-HSA-1912422	7.024049e-01	0.153	0	0
IRS-mediated signalling	R-HSA-112399	7.056203e-01	0.151	0	0
Interleukin-1 family signaling	R-HSA-446652	7.081828e-01	0.150	0	0
Hedgehog 'off' state	R-HSA-5610787	7.100452e-01	0.149	0	0
Interleukin-12 family signaling	R-HSA-447115	7.104688e-01	0.148	0	0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	R-HSA-5693567	7.105611e-01	0.148	0	0
Cleavage of the damaged pyrimidine	R-HSA-110329	7.131054e-01	0.147	0	0
Depyrimidination	R-HSA-73928	7.131054e-01	0.147	0	0
Ca-dependent events	R-HSA-111996	7.131054e-01	0.147	0	0
PTEN Regulation	R-HSA-6807070	7.132772e-01	0.147	0	0
MAPK1/MAPK3 signaling	R-HSA-5684996	7.143622e-01	0.146	0	0
Inflammasomes	R-HSA-622312	7.147377e-01	0.146	0	0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	R-HSA-9029558	7.148782e-01	0.146	0	0
Platelet Adhesion to exposed collagen	R-HSA-75892	7.148782e-01	0.146	0	0
Acyl chain remodeling of DAG and TAG	R-HSA-1482883	7.148782e-01	0.146	0	0
Golgi Cisternae Pericentriolar Stack Reorganization	R-HSA-162658	7.148782e-01	0.146	0	0
PI5P Regulates TP53 Acetylation	R-HSA-6811555	7.148782e-01	0.146	0	0
HDR through MMEJ (alt-NHEJ)	R-HSA-5685939	7.148782e-01	0.146	0	0
CD28 dependent Vav1 pathway	R-HSA-389359	7.148782e-01	0.146	0	0
Maturation of nucleoprotein	R-HSA-9683610	7.148782e-01	0.146	0	0
Replication of the SARS-CoV-1 genome	R-HSA-9682706	7.148782e-01	0.146	0	0
DNA Double-Strand Break Repair	R-HSA-5693532	7.151524e-01	0.146	0	0
Dual incision in TC-NER	R-HSA-6782135	7.166914e-01	0.145	0	0
Defective pyroptosis	R-HSA-9710421	7.254567e-01	0.139	0	0
Signaling by FGFR4	R-HSA-5654743	7.254567e-01	0.139	0	0
PI Metabolism	R-HSA-1483255	7.269055e-01	0.139	0	0
DNA methylation	R-HSA-5334118	7.294807e-01	0.137	0	0
Late endosomal microautophagy	R-HSA-9615710	7.294807e-01	0.137	0	0
Downstream signaling of activated FGFR3	R-HSA-5654708	7.294807e-01	0.137	0	0
Signaling by ERBB2 KD Mutants	R-HSA-9664565	7.294807e-01	0.137	0	0
Platelet calcium homeostasis	R-HSA-418360	7.294807e-01	0.137	0	0
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	7.294807e-01	0.137	0	0
Regulation of CDH11 Expression and Function	R-HSA-9759475	7.294807e-01	0.137	0	0
Synthesis of IPs in the nucleus	R-HSA-1855191	7.351771e-01	0.134	0	0
CLEC7A (Dectin-1) induces NFAT activation	R-HSA-5607763	7.351771e-01	0.134	0	0
NRIF signals cell death from the nucleus	R-HSA-205043	7.351771e-01	0.134	0	0
TP53 Regulates Transcription of Death Receptors and Ligands	R-HSA-6803211	7.351771e-01	0.134	0	0
Respiratory syncytial virus genome transcription	R-HSA-9828642	7.351771e-01	0.134	0	0
HDL assembly	R-HSA-8963896	7.351771e-01	0.134	0	0
P2Y receptors	R-HSA-417957	7.351771e-01	0.134	0	0
SARS-CoV-1 Genome Replication and Transcription	R-HSA-9679514	7.351771e-01	0.134	0	0
Co-inhibition by PD-1	R-HSA-389948	7.397658e-01	0.131	0	0
SHC1 events in ERBB2 signaling	R-HSA-1250196	7.435718e-01	0.129	0	0
Downstream signaling of activated FGFR4	R-HSA-5654716	7.435718e-01	0.129	0	0
Downregulation of ERBB2 signaling	R-HSA-8863795	7.435718e-01	0.129	0	0
Reproduction	R-HSA-1474165	7.482510e-01	0.126	0	0
Signaling by FGFR3	R-HSA-5654741	7.489048e-01	0.126	0	0
DAG and IP3 signaling	R-HSA-1489509	7.489048e-01	0.126	0	0
RSV-host interactions	R-HSA-9833110	7.509101e-01	0.124	0	0
Translesion synthesis by REV1	R-HSA-110312	7.540320e-01	0.123	0	0
Telomere C-strand synthesis initiation	R-HSA-174430	7.540320e-01	0.123	0	0
SHC1 events in EGFR signaling	R-HSA-180336	7.540320e-01	0.123	0	0
RIP-mediated NFkB activation via ZBP1	R-HSA-1810476	7.540320e-01	0.123	0	0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	R-HSA-2173791	7.540320e-01	0.123	0	0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	R-HSA-9673767	7.540320e-01	0.123	0	0
Signaling by PDGFRA extracellular domain mutants	R-HSA-9673770	7.540320e-01	0.123	0	0
IRF3-mediated induction of type I IFN	R-HSA-3270619	7.540320e-01	0.123	0	0
p38MAPK events	R-HSA-171007	7.540320e-01	0.123	0	0
Spry regulation of FGF signaling	R-HSA-1295596	7.540320e-01	0.123	0	0
Protein methylation	R-HSA-8876725	7.540320e-01	0.123	0	0
DNA Damage Reversal	R-HSA-73942	7.540320e-01	0.123	0	0
IRE1alpha activates chaperones	R-HSA-381070	7.540488e-01	0.123	0	0
Negative regulators of DDX58/IFIH1 signaling	R-HSA-936440	7.570289e-01	0.121	0	0
Regulation of TNFR1 signaling	R-HSA-5357905	7.600134e-01	0.119	0	0
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	7.685843e-01	0.114	0	0
Recognition and association of DNA glycosylase with site containing an affected purine	R-HSA-110330	7.698708e-01	0.114	0	0
Downregulation of SMAD2/3:SMAD4 transcriptional activity	R-HSA-2173795	7.698708e-01	0.114	0	0
APC/C:Cdc20 mediated degradation of Securin	R-HSA-174154	7.707206e-01	0.113	0	0
Retrograde transport at the Trans-Golgi-Network	R-HSA-6811440	7.707206e-01	0.113	0	0
Translesion synthesis by POLI	R-HSA-5656121	7.715456e-01	0.113	0	0
Defective GALNT12 causes CRCS1	R-HSA-5083636	7.715456e-01	0.113	0	0
Defective GALNT3 causes HFTC	R-HSA-5083625	7.715456e-01	0.113	0	0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	R-HSA-399955	7.715456e-01	0.113	0	0
Class I peroxisomal membrane protein import	R-HSA-9603798	7.715456e-01	0.113	0	0
Killing mechanisms	R-HSA-9664420	7.715456e-01	0.113	0	0
WNT5:FZD7-mediated leishmania damping	R-HSA-9673324	7.715456e-01	0.113	0	0
KSRP (KHSRP) binds and destabilizes mRNA	R-HSA-450604	7.715456e-01	0.113	0	0
Insulin receptor signalling cascade	R-HSA-74751	7.766869e-01	0.110	0	0
Ion transport by P-type ATPases	R-HSA-936837	7.766869e-01	0.110	0	0
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	7.777943e-01	0.109	0	0
Nonhomologous End-Joining (NHEJ)	R-HSA-5693571	7.810340e-01	0.107	0	0
Resolution of D-loop Structures through Holliday Junction Intermediates	R-HSA-5693568	7.821170e-01	0.107	0	0
Regulation of Expression and Function of Type II Classical Cadherins	R-HSA-9764260	7.821170e-01	0.107	0	0
Cellular response to hypoxia	R-HSA-1234174	7.856405e-01	0.105	0	0
G beta:gamma signalling through CDC42	R-HSA-8964616	7.878131e-01	0.104	0	0
GRB2 events in ERBB2 signaling	R-HSA-1963640	7.878131e-01	0.104	0	0
Translesion synthesis by POLK	R-HSA-5655862	7.878131e-01	0.104	0	0
SHC1 events in ERBB4 signaling	R-HSA-1250347	7.878131e-01	0.104	0	0
Acetylcholine regulates insulin secretion	R-HSA-399997	7.878131e-01	0.104	0	0
Transcriptional regulation of testis differentiation	R-HSA-9690406	7.878131e-01	0.104	0	0
Resolution of D-Loop Structures	R-HSA-5693537	7.937872e-01	0.100	0	0
Respiratory Syncytial Virus Infection Pathway	R-HSA-9820952	7.998221e-01	0.097	0	0
Azathioprine ADME	R-HSA-9748787	8.005117e-01	0.097	0	0
PI3K Cascade	R-HSA-109704	8.005117e-01	0.097	0	0
Kidney development	R-HSA-9830369	8.026867e-01	0.095	0	0
Defective C1GALT1C1 causes TNPS	R-HSA-5083632	8.029231e-01	0.095	0	0
Synthesis of PIPs at the late endosome membrane	R-HSA-1660517	8.029231e-01	0.095	0	0
PI3K events in ERBB2 signaling	R-HSA-1963642	8.029231e-01	0.095	0	0
Glycogen storage diseases	R-HSA-3229121	8.029231e-01	0.095	0	0
Replication of the SARS-CoV-2 genome	R-HSA-9694686	8.029231e-01	0.095	0	0
Mitophagy	R-HSA-5205647	8.049012e-01	0.094	0	0
Hyaluronan metabolism	R-HSA-2142845	8.049012e-01	0.094	0	0
Extracellular matrix organization	R-HSA-1474244	8.068739e-01	0.093	0	0
Neurotransmitter receptors and postsynaptic signal transmission	R-HSA-112314	8.085612e-01	0.092	0	0
Meiotic recombination	R-HSA-912446	8.096932e-01	0.092	0	0
Signaling by FGFR	R-HSA-190236	8.134653e-01	0.090	0	0
MyD88 cascade initiated on plasma membrane	R-HSA-975871	8.134653e-01	0.090	0	0
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	8.134653e-01	0.090	0	0
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	8.134653e-01	0.090	0	0
MAPK6/MAPK4 signaling	R-HSA-5687128	8.147551e-01	0.089	0	0
Downstream signaling of activated FGFR2	R-HSA-5654696	8.154790e-01	0.089	0	0
Downstream signaling of activated FGFR1	R-HSA-5654687	8.154790e-01	0.089	0	0
PERK regulates gene expression	R-HSA-381042	8.154790e-01	0.089	0	0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	R-HSA-9860927	8.154790e-01	0.089	0	0
Signaling by Nuclear Receptors	R-HSA-9006931	8.161770e-01	0.088	0	0
Platelet activation, signaling and aggregation	R-HSA-76002	8.167216e-01	0.088	0	0
RNA Polymerase III Transcription Termination	R-HSA-73980	8.169580e-01	0.088	0	0
ZBP1(DAI) mediated induction of type I IFNs	R-HSA-1606322	8.169580e-01	0.088	0	0
Synaptic adhesion-like molecules	R-HSA-8849932	8.169580e-01	0.088	0	0
Organic anion transport by SLC5/17/25 transporters	R-HSA-428643	8.169580e-01	0.088	0	0
Nucleotide-like (purinergic) receptors	R-HSA-418038	8.169580e-01	0.088	0	0
RNA Polymerase I Promoter Escape	R-HSA-73772	8.185151e-01	0.087	0	0
Orc1 removal from chromatin	R-HSA-68949	8.185151e-01	0.087	0	0
Platelet degranulation	R-HSA-114608	8.208335e-01	0.086	0	0
RAB GEFs exchange GTP for GDP on RABs	R-HSA-8876198	8.217874e-01	0.085	0	0
HSF1 activation	R-HSA-3371511	8.255406e-01	0.083	0	0
PRC2 methylates histones and DNA	R-HSA-212300	8.255406e-01	0.083	0	0
Lysosome Vesicle Biogenesis	R-HSA-432720	8.255406e-01	0.083	0	0
Glycosphingolipid transport	R-HSA-9845576	8.255406e-01	0.083	0	0
FGFR2 mutant receptor activation	R-HSA-1839126	8.255406e-01	0.083	0	0
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	8.261761e-01	0.083	0	0
Cytosolic sensors of pathogen-associated DNA	R-HSA-1834949	8.261761e-01	0.083	0	0
Neuronal System	R-HSA-112316	8.265502e-01	0.083	0	0
PI-3K cascade:FGFR3	R-HSA-5654710	8.299942e-01	0.081	0	0
Impaired BRCA2 binding to PALB2	R-HSA-9709603	8.299942e-01	0.081	0	0
Translesion Synthesis by POLH	R-HSA-110320	8.299942e-01	0.081	0	0
Pyrimidine biosynthesis	R-HSA-500753	8.299942e-01	0.081	0	0
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	8.299942e-01	0.081	0	0
Diseases of hemostasis	R-HSA-9671793	8.299942e-01	0.081	0	0
Other interleukin signaling	R-HSA-449836	8.299942e-01	0.081	0	0
Specification of the neural plate border	R-HSA-9834899	8.299942e-01	0.081	0	0
STING mediated induction of host immune responses	R-HSA-1834941	8.299942e-01	0.081	0	0
Maturation of nucleoprotein	R-HSA-9694631	8.299942e-01	0.081	0	0
The NLRP3 inflammasome	R-HSA-844456	8.299942e-01	0.081	0	0
SARS-CoV-2 Genome Replication and Transcription	R-HSA-9694682	8.299942e-01	0.081	0	0
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	8.317362e-01	0.080	0	0
Extra-nuclear estrogen signaling	R-HSA-9009391	8.326118e-01	0.080	0	0
Voltage gated Potassium channels	R-HSA-1296072	8.351059e-01	0.078	0	0
SIRT1 negatively regulates rRNA expression	R-HSA-427359	8.351059e-01	0.078	0	0
Cleavage of the damaged purine	R-HSA-110331	8.351059e-01	0.078	0	0
Ub-specific processing proteases	R-HSA-5689880	8.365636e-01	0.078	0	0
Negative regulation of the PI3K/AKT network	R-HSA-199418	8.373705e-01	0.077	0	0
PI-3K cascade:FGFR4	R-HSA-5654720	8.421026e-01	0.075	0	0
Defective homologous recombination repair (HRR) due to PALB2 loss of function	R-HSA-9701193	8.421026e-01	0.075	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	R-HSA-9704331	8.421026e-01	0.075	0	0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	R-HSA-9701192	8.421026e-01	0.075	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	R-HSA-9704646	8.421026e-01	0.075	0	0
Glycogen synthesis	R-HSA-3322077	8.421026e-01	0.075	0	0
Co-inhibition by CTLA4	R-HSA-389513	8.421026e-01	0.075	0	0
Negative regulation of MET activity	R-HSA-6807004	8.421026e-01	0.075	0	0
Signaling by NODAL	R-HSA-1181150	8.421026e-01	0.075	0	0
Common Pathway of Fibrin Clot Formation	R-HSA-140875	8.421026e-01	0.075	0	0
Protein hydroxylation	R-HSA-9629569	8.421026e-01	0.075	0	0
Cap-dependent Translation Initiation	R-HSA-72737	8.429454e-01	0.074	0	0
Eukaryotic Translation Initiation	R-HSA-72613	8.429454e-01	0.074	0	0
Metabolism of nitric oxide: NOS3 activation and regulation	R-HSA-202131	8.441945e-01	0.074	0	0
Depurination	R-HSA-73927	8.441945e-01	0.074	0	0
Ca2+ pathway	R-HSA-4086398	8.472988e-01	0.072	0	0
Response of EIF2AK4 (GCN2) to amino acid deficiency	R-HSA-9633012	8.501494e-01	0.071	0	0
Signaling by FGFR1	R-HSA-5654736	8.503937e-01	0.070	0	0
TNF signaling	R-HSA-75893	8.503937e-01	0.070	0	0
MyD88 deficiency (TLR2/4)	R-HSA-5602498	8.533494e-01	0.069	0	0
SHC-mediated cascade:FGFR3	R-HSA-5654704	8.533494e-01	0.069	0	0
Acetylcholine Neurotransmitter Release Cycle	R-HSA-264642	8.533494e-01	0.069	0	0
TNFR1-induced proapoptotic signaling	R-HSA-5357786	8.533494e-01	0.069	0	0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	R-HSA-166058	8.586291e-01	0.066	0	0
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	8.586291e-01	0.066	0	0
Transcriptional Regulation by MECP2	R-HSA-8986944	8.595586e-01	0.066	0	0
Protein ubiquitination	R-HSA-8852135	8.601428e-01	0.065	0	0
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	8.609857e-01	0.065	0	0
Regulation of RUNX3 expression and activity	R-HSA-8941858	8.610187e-01	0.065	0	0
Diseases of Immune System	R-HSA-5260271	8.610187e-01	0.065	0	0
Diseases associated with the TLR signaling cascade	R-HSA-5602358	8.610187e-01	0.065	0	0
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	8.618025e-01	0.065	0	0
Regulation of T cell activation by CD28 family	R-HSA-388841	8.635206e-01	0.064	0	0
Unblocking of NMDA receptors, glutamate binding and activation	R-HSA-438066	8.637956e-01	0.064	0	0
Ras activation upon Ca2+ influx through NMDA receptor	R-HSA-442982	8.637956e-01	0.064	0	0
IRAK4 deficiency (TLR2/4)	R-HSA-5603041	8.637956e-01	0.064	0	0
activated TAK1 mediates p38 MAPK activation	R-HSA-450302	8.637956e-01	0.064	0	0
SHC-mediated cascade:FGFR4	R-HSA-5654719	8.637956e-01	0.064	0	0
Negative regulation of NMDA receptor-mediated neuronal transmission	R-HSA-9617324	8.637956e-01	0.064	0	0
FRS-mediated FGFR3 signaling	R-HSA-5654706	8.637956e-01	0.064	0	0
Molybdenum cofactor biosynthesis	R-HSA-947581	8.637956e-01	0.064	0	0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	R-HSA-9029569	8.644221e-01	0.063	0	0
VEGFR2 mediated vascular permeability	R-HSA-5218920	8.687920e-01	0.061	0	0
Maturation of spike protein	R-HSA-9694548	8.687920e-01	0.061	0	0
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	8.730135e-01	0.059	0	0
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	8.730135e-01	0.059	0	0
PI-3K cascade:FGFR1	R-HSA-5654689	8.734984e-01	0.059	0	0
RAF-independent MAPK1/3 activation	R-HSA-112409	8.734984e-01	0.059	0	0
FRS-mediated FGFR4 signaling	R-HSA-5654712	8.734984e-01	0.059	0	0
NOTCH3 Activation and Transmission of Signal to the Nucleus	R-HSA-9013507	8.734984e-01	0.059	0	0
Ethanol oxidation	R-HSA-71384	8.734984e-01	0.059	0	0
Cholesterol biosynthesis via lathosterol	R-HSA-6807062	8.734984e-01	0.059	0	0
Downregulation of TGF-beta receptor signaling	R-HSA-2173788	8.734984e-01	0.059	0	0
GTP hydrolysis and joining of the 60S ribosomal subunit	R-HSA-72706	8.760192e-01	0.057	0	0
L13a-mediated translational silencing of Ceruloplasmin expression	R-HSA-156827	8.760192e-01	0.057	0	0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	8.760192e-01	0.057	0	0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	R-HSA-6811558	8.775311e-01	0.057	0	0
Integrin cell surface interactions	R-HSA-216083	8.776726e-01	0.057	0	0
Cholesterol biosynthesis	R-HSA-191273	8.776726e-01	0.057	0	0
Developmental Cell Lineages of the Exocrine Pancreas	R-HSA-9820448	8.786722e-01	0.056	0	0
MyD88 dependent cascade initiated on endosome	R-HSA-975155	8.807176e-01	0.055	0	0
Termination of O-glycan biosynthesis	R-HSA-977068	8.825105e-01	0.054	0	0
Carnitine shuttle	R-HSA-200425	8.825105e-01	0.054	0	0
Synthesis of pyrophosphates in the cytosol	R-HSA-1855167	8.825105e-01	0.054	0	0
Organic anion transport by SLCO transporters	R-HSA-879518	8.825105e-01	0.054	0	0
Formation of the ureteric bud	R-HSA-9830674	8.825105e-01	0.054	0	0
Regulation of RUNX2 expression and activity	R-HSA-8939902	8.832932e-01	0.054	0	0
PLC beta mediated events	R-HSA-112043	8.832932e-01	0.054	0	0
TRIF (TICAM1)-mediated TLR4 signaling	R-HSA-937061	8.852652e-01	0.053	0	0
MyD88-independent TLR4 cascade	R-HSA-166166	8.852652e-01	0.053	0	0
DDX58/IFIH1-mediated induction of interferon-alpha/beta	R-HSA-168928	8.856909e-01	0.053	0	0
Unfolded Protein Response (UPR)	R-HSA-381119	8.879076e-01	0.052	0	0
NCAM signaling for neurite out-growth	R-HSA-375165	8.890426e-01	0.051	0	0
Major pathway of rRNA processing in the nucleolus and cytosol	R-HSA-6791226	8.893037e-01	0.051	0	0
TGF-beta receptor signaling activates SMADs	R-HSA-2173789	8.897730e-01	0.051	0	0
Response of Mtb to phagocytosis	R-HSA-9637690	8.897730e-01	0.051	0	0
SHC-mediated cascade:FGFR1	R-HSA-5654688	8.908810e-01	0.050	0	0
Norepinephrine Neurotransmitter Release Cycle	R-HSA-181430	8.908810e-01	0.050	0	0
Signaling by ERBB2 TMD/JMD mutants	R-HSA-9665686	8.908810e-01	0.050	0	0
Replacement of protamines by nucleosomes in the male pronucleus	R-HSA-9821993	8.908810e-01	0.050	0	0
Signaling by FLT3 ITD and TKD mutants	R-HSA-9703648	8.908810e-01	0.050	0	0
Plasma lipoprotein assembly	R-HSA-8963898	8.908810e-01	0.050	0	0
rRNA processing in the nucleus and cytosol	R-HSA-8868773	8.956513e-01	0.048	0	0
Amine ligand-binding receptors	R-HSA-375280	8.960447e-01	0.048	0	0
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	8.980362e-01	0.047	0	0
PI-3K cascade:FGFR2	R-HSA-5654695	8.986557e-01	0.046	0	0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	R-HSA-5693554	8.986557e-01	0.046	0	0
Long-term potentiation	R-HSA-9620244	8.986557e-01	0.046	0	0
FRS-mediated FGFR1 signaling	R-HSA-5654693	8.986557e-01	0.046	0	0
Defects in cobalamin (B12) metabolism	R-HSA-3296469	8.986557e-01	0.046	0	0
Hyaluronan degradation	R-HSA-2160916	8.986557e-01	0.046	0	0
MicroRNA (miRNA) biogenesis	R-HSA-203927	8.986557e-01	0.046	0	0
PIWI-interacting RNA (piRNA) biogenesis	R-HSA-5601884	8.986557e-01	0.046	0	0
Formation of the nephric duct	R-HSA-9830364	8.986557e-01	0.046	0	0
Cellular response to chemical stress	R-HSA-9711123	9.004140e-01	0.046	0	0
Fanconi Anemia Pathway	R-HSA-6783310	9.019827e-01	0.045	0	0
Glutamate Neurotransmitter Release Cycle	R-HSA-210500	9.058768e-01	0.043	0	0
MET activates PTK2 signaling	R-HSA-8874081	9.058768e-01	0.043	0	0
Metalloprotease DUBs	R-HSA-5689901	9.058768e-01	0.043	0	0
Attachment of bacteria to epithelial cells	R-HSA-9638630	9.058768e-01	0.043	0	0
TRP channels	R-HSA-3295583	9.058768e-01	0.043	0	0
Sphingolipid catabolism	R-HSA-9845614	9.058768e-01	0.043	0	0
Activated NOTCH1 Transmits Signal to the Nucleus	R-HSA-2122948	9.058768e-01	0.043	0	0
Formation of TC-NER Pre-Incision Complex	R-HSA-6781823	9.076029e-01	0.042	0	0
Formation of the ternary complex, and subsequently, the 43S complex	R-HSA-72695	9.076029e-01	0.042	0	0
Packaging Of Telomere Ends	R-HSA-171306	9.125839e-01	0.040	0	0
Cobalamin (Cbl) metabolism	R-HSA-9759218	9.125839e-01	0.040	0	0
SHC-mediated cascade:FGFR2	R-HSA-5654699	9.125839e-01	0.040	0	0
RNA Polymerase I Promoter Opening	R-HSA-73728	9.125839e-01	0.040	0	0
TNFR1-induced NF-kappa-B signaling pathway	R-HSA-5357956	9.125839e-01	0.040	0	0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	R-HSA-193807	9.125839e-01	0.040	0	0
G-protein mediated events	R-HSA-112040	9.141482e-01	0.039	0	0
Interleukin-1 signaling	R-HSA-9020702	9.152010e-01	0.038	0	0
Co-stimulation by CD28	R-HSA-389356	9.179494e-01	0.037	0	0
FRS-mediated FGFR2 signaling	R-HSA-5654700	9.188133e-01	0.037	0	0
Telomere Extension By Telomerase	R-HSA-171319	9.188133e-01	0.037	0	0
PINK1-PRKN Mediated Mitophagy	R-HSA-5205685	9.188133e-01	0.037	0	0
Negative regulation of FGFR3 signaling	R-HSA-5654732	9.188133e-01	0.037	0	0
ATF4 activates genes in response to endoplasmic reticulum stress	R-HSA-380994	9.188133e-01	0.037	0	0
Degradation of the extracellular matrix	R-HSA-1474228	9.189477e-01	0.037	0	0
Negative regulation of FGFR4 signaling	R-HSA-5654733	9.245992e-01	0.034	0	0
Nitric oxide stimulates guanylate cyclase	R-HSA-392154	9.245992e-01	0.034	0	0
DAP12 signaling	R-HSA-2424491	9.299731e-01	0.032	0	0
GABA synthesis, release, reuptake and degradation	R-HSA-888590	9.299731e-01	0.032	0	0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	R-HSA-1474151	9.299731e-01	0.032	0	0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	R-HSA-1234176	9.314458e-01	0.031	0	0
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	9.327542e-01	0.030	0	0
Neurotransmitter release cycle	R-HSA-112310	9.333356e-01	0.030	0	0
Beta-catenin independent WNT signaling	R-HSA-3858494	9.333614e-01	0.030	0	0
Respiratory syncytial virus (RSV) attachment and entry	R-HSA-9820960	9.349643e-01	0.029	0	0
Budding and maturation of HIV virion	R-HSA-162588	9.349643e-01	0.029	0	0
Molecules associated with elastic fibres	R-HSA-2129379	9.349643e-01	0.029	0	0
Signaling by Hedgehog	R-HSA-5358351	9.384648e-01	0.028	0	0
Adaptive Immune System	R-HSA-1280218	9.415030e-01	0.026	0	0
Signaling by Insulin receptor	R-HSA-74752	9.423707e-01	0.026	0	0
Plasma lipoprotein assembly, remodeling, and clearance	R-HSA-174824	9.423707e-01	0.026	0	0
G-protein beta:gamma signalling	R-HSA-397795	9.439055e-01	0.025	0	0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	R-HSA-442742	9.439055e-01	0.025	0	0
Assembly of the ORC complex at the origin of replication	R-HSA-68616	9.439055e-01	0.025	0	0
Cardiogenesis	R-HSA-9733709	9.439055e-01	0.025	0	0
Negative regulation of FGFR1 signaling	R-HSA-5654726	9.439055e-01	0.025	0	0
Recycling of bile acids and salts	R-HSA-159418	9.439055e-01	0.025	0	0
Regulation of necroptotic cell death	R-HSA-5675482	9.439055e-01	0.025	0	0
TCR signaling	R-HSA-202403	9.456941e-01	0.024	0	0
Toll-like Receptor Cascades	R-HSA-168898	9.457397e-01	0.024	0	0
Paracetamol ADME	R-HSA-9753281	9.461981e-01	0.024	0	0
Acyl chain remodelling of PC	R-HSA-1482788	9.479044e-01	0.023	0	0
Transmission across Chemical Synapses	R-HSA-112315	9.479455e-01	0.023	0	0
NR1H2 and NR1H3-mediated signaling	R-HSA-9024446	9.495007e-01	0.023	0	0
Translation of Structural Proteins	R-HSA-9694635	9.495007e-01	0.023	0	0
eNOS activation	R-HSA-203615	9.516184e-01	0.022	0	0
SARS-CoV-1 modulates host translation machinery	R-HSA-9735869	9.516184e-01	0.022	0	0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	R-HSA-983170	9.516184e-01	0.022	0	0
Negative regulation of FGFR2 signaling	R-HSA-5654727	9.516184e-01	0.022	0	0
Regulation of TLR by endogenous ligand	R-HSA-5686938	9.516184e-01	0.022	0	0
NPAS4 regulates expression of target genes	R-HSA-9768919	9.516184e-01	0.022	1	1
PCP/CE pathway	R-HSA-4086400	9.521662e-01	0.021	0	0
SCF-beta-TrCP mediated degradation of Emi1	R-HSA-174113	9.550678e-01	0.020	0	0
Regulation of Apoptosis	R-HSA-169911	9.550678e-01	0.020	0	0
Acyl chain remodelling of PE	R-HSA-1482839	9.550678e-01	0.020	0	0
Defects in vitamin and cofactor metabolism	R-HSA-3296482	9.550678e-01	0.020	0	0
Disorders of transmembrane transporters	R-HSA-5619115	9.565984e-01	0.019	0	0
GPVI-mediated activation cascade	R-HSA-114604	9.582715e-01	0.019	0	0
Regulation of TP53 Degradation	R-HSA-6804757	9.582715e-01	0.019	0	0
Formation of Fibrin Clot (Clotting Cascade)	R-HSA-140877	9.582715e-01	0.019	0	0
rRNA processing	R-HSA-72312	9.591915e-01	0.018	0	0
Post-translational protein phosphorylation	R-HSA-8957275	9.592677e-01	0.018	0	0
Cardiac conduction	R-HSA-5576891	9.595037e-01	0.018	0	0
Sphingolipid de novo biosynthesis	R-HSA-1660661	9.604131e-01	0.018	0	0
Hemostasis	R-HSA-109582	9.607929e-01	0.017	1	0
Degradation of AXIN	R-HSA-4641257	9.612470e-01	0.017	0	0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	R-HSA-9762114	9.612470e-01	0.017	0	0
NCAM1 interactions	R-HSA-419037	9.612470e-01	0.017	0	0
SLC-mediated transport of organic cations	R-HSA-549127	9.612470e-01	0.017	0	0
tRNA processing in the mitochondrion	R-HSA-6785470	9.640104e-01	0.016	0	0
Elastic fibre formation	R-HSA-1566948	9.640104e-01	0.016	0	0
Biofilm formation	R-HSA-9931953	9.640104e-01	0.016	0	0
Purine salvage	R-HSA-74217	9.640104e-01	0.016	0	0
RIPK1-mediated regulated necrosis	R-HSA-5213460	9.640104e-01	0.016	0	0
Regulation of TP53 Expression and Degradation	R-HSA-6806003	9.665770e-01	0.015	0	0
Respiratory syncytial virus (RSV) genome replication, transcription and translation	R-HSA-9820965	9.665770e-01	0.015	0	0
rRNA modification in the nucleus and cytosol	R-HSA-6790901	9.671313e-01	0.015	0	0
Glycogen metabolism	R-HSA-8982491	9.689606e-01	0.014	0	0
Negative regulation of NOTCH4 signaling	R-HSA-9604323	9.689606e-01	0.014	0	0
rRNA processing in the mitochondrion	R-HSA-8868766	9.689606e-01	0.014	0	0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	9.691161e-01	0.014	0	0
Response of endothelial cells to shear stress	R-HSA-9860931	9.699702e-01	0.013	0	0
SPOP-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929491	9.711744e-01	0.013	0	0
Degradation of GLI1 by the proteasome	R-HSA-5610780	9.732304e-01	0.012	0	0
Intra-Golgi traffic	R-HSA-6811438	9.732304e-01	0.012	0	0
Scavenging by Class A Receptors	R-HSA-3000480	9.732304e-01	0.012	0	0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	R-HSA-9615017	9.732304e-01	0.012	0	0
Translation of Structural Proteins	R-HSA-9683701	9.732304e-01	0.012	0	0
Formation of the cornified envelope	R-HSA-6809371	9.744387e-01	0.011	0	0
Cellular response to starvation	R-HSA-9711097	9.744576e-01	0.011	0	0
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	9.744576e-01	0.011	0	0
Cytosolic tRNA aminoacylation	R-HSA-379716	9.751399e-01	0.011	0	0
SRP-dependent cotranslational protein targeting to membrane	R-HSA-1799339	9.755783e-01	0.011	0	0
Stimuli-sensing channels	R-HSA-2672351	9.768180e-01	0.010	0	0
DAP12 interactions	R-HSA-2172127	9.785603e-01	0.009	0	0
Cobalamin (Cbl, vitamin B12) transport and metabolism	R-HSA-196741	9.785603e-01	0.009	0	0
Synthesis of Leukotrienes (LT) and Eoxins (EX)	R-HSA-2142691	9.785603e-01	0.009	0	0
Surfactant metabolism	R-HSA-5683826	9.785603e-01	0.009	0	0
Fatty acyl-CoA biosynthesis	R-HSA-75105	9.788073e-01	0.009	0	0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	R-HSA-975956	9.792468e-01	0.009	0	0
Somitogenesis	R-HSA-9824272	9.800899e-01	0.009	0	0
Asymmetric localization of PCP proteins	R-HSA-4608870	9.800899e-01	0.009	0	0
ECM proteoglycans	R-HSA-3000178	9.801054e-01	0.009	0	0
Metabolism of cofactors	R-HSA-8978934	9.801054e-01	0.009	0	0
Eukaryotic Translation Elongation	R-HSA-156842	9.803962e-01	0.009	0	0
Late SARS-CoV-2 Infection Events	R-HSA-9772573	9.803962e-01	0.009	0	0
Nonsense-Mediated Decay (NMD)	R-HSA-927802	9.812085e-01	0.008	0	0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	R-HSA-975957	9.812085e-01	0.008	0	0
FCERI mediated MAPK activation	R-HSA-2871796	9.812085e-01	0.008	0	0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	R-HSA-983695	9.814846e-01	0.008	0	0
Purinergic signaling in leishmaniasis infection	R-HSA-9660826	9.815104e-01	0.008	0	0
Cell recruitment (pro-inflammatory response)	R-HSA-9664424	9.815104e-01	0.008	0	0
TAK1-dependent IKK and NF-kappa-B activation	R-HSA-445989	9.828297e-01	0.008	0	0
Synthesis of PC	R-HSA-1483191	9.828297e-01	0.008	0	0
Cellular responses to mechanical stimuli	R-HSA-9855142	9.830970e-01	0.007	0	0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	R-HSA-381426	9.839724e-01	0.007	0	0
Metal ion SLC transporters	R-HSA-425410	9.840549e-01	0.007	0	0
Formation of a pool of free 40S subunits	R-HSA-72689	9.844142e-01	0.007	0	0
Degradation of CDH1	R-HSA-9766229	9.851928e-01	0.006	0	0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	R-HSA-532668	9.851928e-01	0.006	0	0
Phospholipid metabolism	R-HSA-1483257	9.852009e-01	0.006	0	0
Potassium Channels	R-HSA-1296071	9.852879e-01	0.006	0	0
Ion channel transport	R-HSA-983712	9.857271e-01	0.006	0	0
Regulation of RAS by GAPs	R-HSA-5658442	9.862495e-01	0.006	0	0
C-type lectin receptors (CLRs)	R-HSA-5621481	9.863265e-01	0.006	0	0
Class I MHC mediated antigen processing & presentation	R-HSA-983169	9.868154e-01	0.006	0	0
Leishmania infection	R-HSA-9658195	9.870019e-01	0.006	0	0
Parasitic Infection Pathways	R-HSA-9824443	9.870019e-01	0.006	0	0
Activation of NF-kappaB in B cells	R-HSA-1169091	9.872308e-01	0.006	0	0
Complex IV assembly	R-HSA-9864848	9.872308e-01	0.006	0	0
SLC-mediated transport of organic anions	R-HSA-9955298	9.872606e-01	0.006	0	0
Synthesis of bile acids and bile salts	R-HSA-192105	9.876362e-01	0.005	0	0
Developmental Lineage of Pancreatic Acinar Cells	R-HSA-9925561	9.880518e-01	0.005	0	0
Transcriptional Regulation by NPAS4	R-HSA-9634815	9.881422e-01	0.005	1	0
ABC-family proteins mediated transport	R-HSA-382556	9.883356e-01	0.005	0	0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	R-HSA-9856530	9.887950e-01	0.005	0	0
Amino acids regulate mTORC1	R-HSA-9639288	9.889886e-01	0.005	0	0
Nucleotide biosynthesis	R-HSA-8956320	9.889886e-01	0.005	0	0
Amyloid fiber formation	R-HSA-977225	9.894931e-01	0.005	0	0
Disease	R-HSA-1643685	9.898452e-01	0.004	1	0
Interferon gamma signaling	R-HSA-877300	9.899628e-01	0.004	0	0
G alpha (z) signalling events	R-HSA-418597	9.905046e-01	0.004	0	0
Opioid Signalling	R-HSA-111885	9.907710e-01	0.004	1	0
Dectin-2 family	R-HSA-5621480	9.918120e-01	0.004	0	0
Synthesis of PA	R-HSA-1483166	9.918120e-01	0.004	0	0
Platelet homeostasis	R-HSA-418346	9.922676e-01	0.003	0	0
Early SARS-CoV-2 Infection Events	R-HSA-9772572	9.923966e-01	0.003	0	0
Peroxisomal protein import	R-HSA-9033241	9.929395e-01	0.003	0	0
tRNA Aminoacylation	R-HSA-379724	9.934437e-01	0.003	0	0
Asparagine N-linked glycosylation	R-HSA-446203	9.936866e-01	0.003	0	0
Infectious disease	R-HSA-5663205	9.937178e-01	0.003	0	0
Peptide chain elongation	R-HSA-156902	9.937411e-01	0.003	0	0
Bile acid and bile salt metabolism	R-HSA-194068	9.939024e-01	0.003	0	0
Endogenous sterols	R-HSA-211976	9.939119e-01	0.003	0	0
Nucleotide salvage	R-HSA-8956321	9.939119e-01	0.003	0	0
ER-Phagosome pathway	R-HSA-1236974	9.941359e-01	0.003	0	0
Downstream TCR signaling	R-HSA-202424	9.945063e-01	0.002	0	0
Complex I biogenesis	R-HSA-6799198	9.947504e-01	0.002	0	0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	R-HSA-9954714	9.948537e-01	0.002	0	0
Regulation of expression of SLITs and ROBOs	R-HSA-9010553	9.949754e-01	0.002	0	0
tRNA modification in the nucleus and cytosol	R-HSA-6782315	9.957969e-01	0.002	0	0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	R-HSA-193368	9.960972e-01	0.002	0	0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	R-HSA-9954716	9.962922e-01	0.002	0	0
O-linked glycosylation of mucins	R-HSA-913709	9.963760e-01	0.002	0	0
Regulated Necrosis	R-HSA-5218859	9.963760e-01	0.002	0	0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide	R-HSA-9954709	9.965283e-01	0.002	0	0
Eukaryotic Translation Termination	R-HSA-72764	9.965283e-01	0.002	0	0
CLEC7A (Dectin-1) signaling	R-HSA-5607764	9.967496e-01	0.001	0	0
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	9.970224e-01	0.001	0	0
Glycerophospholipid biosynthesis	R-HSA-1483206	9.970224e-01	0.001	0	0
Diseases associated with O-glycosylation of proteins	R-HSA-3906995	9.970986e-01	0.001	0	0
Hedgehog 'on' state	R-HSA-5632684	9.970986e-01	0.001	0	0
Purine catabolism	R-HSA-74259	9.973060e-01	0.001	0	0
Interconversion of nucleotide di- and triphosphates	R-HSA-499943	9.973060e-01	0.001	0	0
Diseases of carbohydrate metabolism	R-HSA-5663084	9.974985e-01	0.001	0	0
Selenocysteine synthesis	R-HSA-2408557	9.976643e-01	0.001	0	0
ROS and RNS production in phagocytes	R-HSA-1222556	9.976773e-01	0.001	0	0
Citric acid cycle (TCA cycle)	R-HSA-71403	9.978433e-01	0.001	0	0
Viral mRNA Translation	R-HSA-192823	9.979545e-01	0.001	0	0
Post-translational protein modification	R-HSA-597592	9.980770e-01	0.001	0	0
Antigen processing-Cross presentation	R-HSA-1236975	9.986282e-01	0.001	0	0
G alpha (q) signalling events	R-HSA-416476	9.989413e-01	0.000	0	0
Metabolism of steroids	R-HSA-8957322	9.989669e-01	0.000	0	0
Regulation of PD-L1(CD274) Post-translational modification	R-HSA-9909615	9.990463e-01	0.000	0	0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	R-HSA-163841	9.991145e-01	0.000	0	0
FCERI mediated Ca+2 mobilization	R-HSA-2871809	9.992497e-01	0.000	0	0
Immune System	R-HSA-168256	9.992822e-01	0.000	0	0
Peptide hormone metabolism	R-HSA-2980736	9.993443e-01	0.000	0	0
Infection with Mycobacterium tuberculosis	R-HSA-9635486	9.994994e-01	0.000	0	0
Cell surface interactions at the vascular wall	R-HSA-202733	9.995035e-01	0.000	0	0
FCGR activation	R-HSA-2029481	9.995110e-01	0.000	0	0
Mitochondrial protein degradation	R-HSA-9837999	9.995460e-01	0.000	0	0
Neutrophil degranulation	R-HSA-6798695	9.995627e-01	0.000	0	0
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	9.996367e-01	0.000	0	0
Neddylation	R-HSA-8951664	9.996450e-01	0.000	0	0
Regulation of insulin secretion	R-HSA-422356	9.996868e-01	0.000	0	0
Protein localization	R-HSA-9609507	9.997052e-01	0.000	0	0
Keratinization	R-HSA-6805567	9.997779e-01	0.000	0	0
Metabolism of carbohydrates and carbohydrate derivatives	R-HSA-71387	9.997844e-01	0.000	0	0
Selenoamino acid metabolism	R-HSA-2408522	9.998542e-01	0.000	0	0
Ribosome-associated quality control	R-HSA-9948299	9.998717e-01	0.000	0	0
Antimicrobial peptides	R-HSA-6803157	9.998894e-01	0.000	0	0
FCERI mediated NF-kB activation	R-HSA-2871837	9.999206e-01	0.000	0	0
FCGR3A-mediated IL10 synthesis	R-HSA-9664323	9.999710e-01	0.000	0	0
Nucleotide catabolism	R-HSA-8956319	9.999768e-01	0.000	0	0
Sensory perception of taste	R-HSA-9717189	9.999814e-01	0.000	0	0
Sphingolipid metabolism	R-HSA-428157	9.999878e-01	0.000	0	0
Integration of energy metabolism	R-HSA-163685	9.999881e-01	0.000	0	0
O-linked glycosylation	R-HSA-5173105	9.999890e-01	0.000	0	0
Metabolism of nucleotides	R-HSA-15869	9.999926e-01	0.000	0	0
Respiratory electron transport	R-HSA-611105	9.999930e-01	0.000	0	0
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	9.999961e-01	0.000	0	0
Drug ADME	R-HSA-9748784	9.999963e-01	0.000	0	0
Arachidonate metabolism	R-HSA-2142753	9.999967e-01	0.000	0	0
Glycosaminoglycan metabolism	R-HSA-1630316	9.999976e-01	0.000	0	0
Translation	R-HSA-72766	9.999981e-01	0.000	0	0
Cytochrome P450 - arranged by substrate type	R-HSA-211897	9.999989e-01	0.000	0	0
G alpha (s) signalling events	R-HSA-418555	9.999992e-01	0.000	0	0
Leishmania parasite growth and survival	R-HSA-9664433	9.999994e-01	0.000	0	0
Anti-inflammatory response favouring Leishmania parasite infection	R-HSA-9662851	9.999994e-01	0.000	0	0
Diseases of glycosylation	R-HSA-3781865	9.999997e-01	0.000	0	0
Peptide ligand-binding receptors	R-HSA-375276	9.999998e-01	0.000	0	0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	R-HSA-198933	9.999998e-01	0.000	0	0
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	9.999998e-01	0.000	0	0
Innate Immune System	R-HSA-168249	9.999999e-01	0.000	0	0
Bacterial Infection Pathways	R-HSA-9824439	9.999999e-01	0.000	0	0
Infection with Enterobacteria	R-HSA-9640148	9.999999e-01	0.000	0	0
Metabolism of proteins	R-HSA-392499	1.000000e+00	0.000	0	0
GPCR downstream signalling	R-HSA-388396	1.000000e+00	0.000	1	0
Phase I - Functionalization of compounds	R-HSA-211945	1.000000e+00	0.000	0	0
Metabolism of vitamins and cofactors	R-HSA-196854	1.000000e+00	0.000	0	0
Aerobic respiration and respiratory electron transport	R-HSA-1428517	1.000000e+00	0.000	0	0
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	1.000000e+00	0.000	0	0
SLC-mediated transmembrane transport	R-HSA-425407	1.000000e+00	0.000	0	0
Signaling by GPCR	R-HSA-372790	1.000000e+00	0.000	1	0
G alpha (i) signalling events	R-HSA-418594	1.000000e+00	0.000	1	0
Transport of small molecules	R-HSA-382551	1.000000e+00	0.000	0	0
Fatty acid metabolism	R-HSA-8978868	1.000000e+00	0.000	0	0
Diseases of metabolism	R-HSA-5668914	1.000000e+00	0.000	0	0
Metabolism of lipids	R-HSA-556833	1.000000e+00	0.000	0	0
GPCR ligand binding	R-HSA-500792	1.000000e+00	0.000	0	0
Biological oxidations	R-HSA-211859	1.000000e+00	0.000	0	0
Expression and translocation of olfactory receptors	R-HSA-9752946	1.000000e+00	-0.000	0	0
Olfactory Signaling Pathway	R-HSA-381753	1.000000e+00	-0.000	0	0
Metabolism	R-HSA-1430728	1.000000e+00	-0.000	0	0
Sensory Perception	R-HSA-9709957	1.000000e+00	-0.000	0	0
Metabolism of amino acids and derivatives	R-HSA-71291	1.000000e+00	-0.000	0	0
DARPP-32 events	R-HSA-180024	1.000000e+00	0.000	1	1
Activated NTRK2 signals through CDK5	R-HSA-9032845	1.000000e+00	0.000	1	1