AURC

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Y Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Log-Odds: Y Sites / Y Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 S939 Sugiyama POTEF A26C1B VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NKT7 S1482 Sugiyama RGPD3 RGP3 DEAKTAQEKDsLItPHVsRsstPREsPCGKIAVAVLEEtTR
A6NMY6 S164 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGS
O00299 S211 Sugiyama CLIC1 G6 NCC27 CKKYRGFTIPEAFRGVHRYLsNAyAREEFAstCPDDEEIEL
O00458 S14 Sugiyama IFRD1 _______MPKNKKRNtPHRGssAGGGGsGAAAATAATAGGQ
O00469 S597 Sugiyama PLOD2 DELVEEMEHyGKWSGGKHHDsRIsGGyENVPTDDIHMKQVD
O00469 S600 Sugiyama PLOD2 VEEMEHyGKWSGGKHHDsRIsGGyENVPTDDIHMKQVDLEN
O00571 S594 Sugiyama DDX3X DBX DDX3 MAyEHHyKGssRGRSKssRFsGGFGARDYRQssGAssssFs
O00571 S605 Sugiyama DDX3X DBX DDX3 RGRSKssRFsGGFGARDYRQssGAssssFsssRAsSsRSGG
O00571 S71 Sugiyama DDX3X DBX DDX3 GFyDKDSSGWsssKDKDAyssFGsRsDsRGKssFFsDRGsG
O14617 S658 Sugiyama AP3D1 PRO0039 DERPRAVFHEEEQRRPKHRPsEADEEELARRREARKQEQAN
O14618 S267 Sugiyama CCS DGLTIWEERGRPIAGKGRKEsAQPPAHL_____________
O14715 S1481 Sugiyama RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3 DEAKTAQEKDsLItPHVsRsstPREsPCGKIAVAVLEEITR
O14732 S160 Sugiyama IMPA2 IMP.18P RLYTGRRGRGAFCNGQRLRVsGETDLSKALVLTEIGPKRDP
O14907 S61 Sugiyama TAX1BP3 TIP1 PSQNPFSEDKTDKGIYVtRVsEGGPAEIAGLQIGDKIMQVN
O14980 S1055 Sugiyama XPO1 CRM1 LEEREIALRQADEEKHKRQMsVPGIFNPHEIPEEMCD____
O15013 S1232 Sugiyama ARHGEF10 KIAA0294 VKFIVLATALHEKDKDKsRDsLAPGPEPQDEDQKDALPSGG
O15037 S291 Sugiyama KHNYN KIAA0323 GWKELPGEEAWEREVALRPQsVGGGAREsAPLKGKALGKEE
O15037 S299 Sugiyama KHNYN KIAA0323 EAWEREVALRPQsVGGGAREsAPLKGKALGKEEIALGGGGF
O15067 S1053 Sugiyama PFAS KIAA0361 RGLRERMGPSYCLPPTFPKAsVPREPGGPsPRVAILREEGS
O15067 S215 Sugiyama PFAS KIAA0361 LDSWDLDFYTKRFQELQRNPstVEAFDLAQsNsEHSRHWFF
O15143 S328 Sugiyama ARPC1B ARC41 KAssEGGtAAGAGLDsLHKNsVsQIsVLsGGKAKCSQFCTT
O15212 T107 Sugiyama PFDN6 HKE2 PFD6 IKRYESQLRDLERQsEQQREtLAQLQQEFQRAQAAKAGAPG
O15372 S290 Sugiyama EIF3H EIF3S3 QQQQKHQYQQRRQQENMQRQsRGEPPLPEEDLsKLFKPPQP
O15392 S20 EPSD|PSP BIRC5 API4 IAP4 _MGAPTLPPAWQPFLKDHRIstFKNWPFLEGCACtPERMAE
O15523 S592 Sugiyama DDX3Y DBY MAyEHHyKGGSRGRSKSNRFsGGFGARDYRQSSGSSSSGFG
O15523 S71 Sugiyama DDX3Y DBY GFHDKDSSGWSCSKDKDAyssFGsRDSRGKPGYFSERGSGS
O43175 S166 Sugiyama PHGDH PGDH3 KtLGILGLGRIGREVATRMQsFGMKTIGYDPIISPEVSASF
O43237 S383 Sugiyama DYNC1LI2 DNCLI2 LIC2 LMKQQSLLAKQPATPtRAsEsPARGPsGsPRTQGRGGPAsV
O43237 S389 Sugiyama DYNC1LI2 DNCLI2 LIC2 LLAKQPATPtRAsEsPARGPsGsPRTQGRGGPAsVPsssPG
O43237 T378 Sugiyama DYNC1LI2 DNCLI2 LIC2 DEQVFLMKQQSLLAKQPATPtRAsEsPARGPsGsPRTQGRG
O43823 S124 Sugiyama AKAP8 AKAP95 SKEGGRGGsGGGGEGIQDREssFRFQPFESYDSRPCLPEHN
O43847 S94 Sugiyama NRDC NRD1 ENSRVARLGADEsEEEGRRGsLsNAGDPEIVKsPsDPKQYR
O43852 Y263 Sugiyama CALU KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60739 T46 Sugiyama EIF1B GTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKKK
O60814 S37 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
O75116 S762 Sugiyama ROCK2 KIAA0619 EERTLKQKVENLLLEAEKRCsLLDCDLKQSQQKINELLKQK
O75157 S205 Sugiyama TSC22D2 KIAA0669 TILZ4 yYERDSDSSVLTRSGDCIRHssTFDQTAERDSGLGATGGSV
O75369 S458 Sugiyama FLNB FLN1L FLN3 TABP TAP PKsPFVVQVGEACNPNACRAsGRGLQPKGVRIRETTDFKVD
O75396 S137 Sugiyama SEC22B SEC22L1 TFIQKTKKLYIDSRARRNLGsINtELQDVQRIMVANIEEVL
O75410 S228 SIGNOR|EPSD|PSP TACC1 KIAA1103 SAEADLKAGNsCPELVPSRRsKLRKPKPVPLRKKAIGGEFs
O75534 S782 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR LDDAsAPRLMVLRQPRGPDNsMGFGAERKIRQAGVID____
O75665 S899 Sugiyama OFD1 CXorf5 EEKIREQQVKERRQREERRQsNLQEVLERERRELEKLyQER
O95155 S79 Sugiyama UBE4B HDNB1 KIAA0684 UFD2 NMtPAtsPIGASGVAHRsQssEGVssLsssPsNsLEtQsQs
O95263 S428 Sugiyama PDE8B PIG22 FRYKNRRKESIDVKSISSRGsDAPSLQNRRYPSMARIHsMt
O95336 T74 Sugiyama PGLS LARELPAAVAPAGPASLARWtLGFCDERLVPFDHAEStyGL
O95456 S180 Sugiyama PSMG1 C21LRP DSCR2 PAC1 KNMQITILTCRHVTDYKTSEsTGsLPsPFLRALKTQNFKDS
O95456 S183 Sugiyama PSMG1 C21LRP DSCR2 PAC1 QITILTCRHVTDYKTSEsTGsLPsPFLRALKTQNFKDSACC
O95817 S194 Sugiyama BAG3 BIS PAAsDCsssSsSAsLPssGRssLGsHQLPRGyISIPVIHEQ
O95831 S100 Sugiyama AIFM1 AIF PDCD8 AGAYAYKTMKEDEKRyNERIsGLGLtPEQKQKKAALsAsEG
O95881 T159 Sugiyama TXNDC12 TLP19 UNQ713/PRO1376 yFyVsAEQVVQGMKEAQERLtGDAFRKKHLEDEL_______
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00491 S163 Sugiyama PNP NP GQNPLRGPNDERFGDRFPAMsDAyDRtMRQRALstWKQMGE
P00491 S176 Sugiyama PNP NP GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA
P00558 S174 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL
P00558 S175 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN
P00558 S393 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA
P00558 S399 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P00568 S58 Sugiyama AK1 stGDLLRSEVSSGSARGKKLsEIMEKGQLVPLETVLDMLRD
P02545 S437 Sugiyama LMNA LMN1 KKRKLEstEsRssFsQHARtsGRVAVEEVDEEGKFVRLRNK
P02545 S463 Sugiyama LMNA LMN1 EEVDEEGKFVRLRNKsNEDQsMGNWQIKRQNGDDPLLtYRF
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S356 Sugiyama ALDOA ALDA sLACQGKytPsGQAGAAAsEsLFVsNHAy____________
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04083 S173 Sugiyama ANXA1 ANX1 LPC1 NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG
P04083 S182 Sugiyama ANXA1 ANX1 LPC1 RDLAKDItsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsD
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04406 S210 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05783 S177 Sugiyama KRT18 CYK18 PIG46 ARLAADDFRVKyETELAMRQsVENDIHGLRKVIDDTNItRL
P05787 S291 Sugiyama KRT8 CYK8 ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P05787 S330 Sugiyama KRT8 CYK8 MNRNISRLQAEIEGLKGQRAsLEAAIADAEQRGELAIKDAN
P05787 S34 Sugiyama KRT8 CYK8 TSGPRAFSSRsYTSGPGSRIsSSSFSRVGSSNFRGGLGGGY
P06733 S40 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T302 Sugiyama LDHB YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 S393 Sugiyama PGK2 PGKB GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA
P07205 S399 Sugiyama PGK2 PGKB CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 S273 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB IKtHILLFLPKSVSDYDGKLsNFKTAAEsFKGKILFIFIDS
P07237 T340 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB LEEEMTKyKPEsEELtAERItEFCHRFLEGKIKPHLMsQEL
P07355 S164 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGs
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07737 S57 Sugiyama PFN1 GKtFVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDs
P07737 S58 Sugiyama PFN1 KtFVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsL
P07737 S72 Sugiyama PFN1 VGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFsMDLRtKs
P07737 S77 Sugiyama PFN1 ssFyVNGLtLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAP
P07737 T65 Sugiyama PFN1 PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs
P07737 Y60 Sugiyama PFN1 FVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQ
P07814 S1473 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 CEDWIKKtTARDQDLEPGAPsMGAKSLCIPFKPLCELQPGA
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 S739 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV
P07814 Y827 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S164 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGT
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S50 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900 S623 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA tyGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsII
P07900 S63 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN
P07900 T171 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILHLK
P07900 T317 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P07900 Y284 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI
P07900 Y309 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF
P07900 Y313 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG
P08174 S54 Sugiyama CD55 CR DAF GDCGLPPDVPNAQPALEGRTsFPEDtVItyKCEEsFVKIPG
P08238 S159 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB VAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGT
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S45 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238 S452 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AFSKNLKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEy
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S470 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEs
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 S58 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN
P08238 T166 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILHLK
P08238 T309 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238 Y276 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI
P08238 Y301 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF
P08238 Y305 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG
P08670 S325 Sugiyama VIM NNDALRQAKQESTEYRRQVQsLtCEVDALKGtNEsLERQMR
P08708 Y84 Sugiyama RPS17 RPS17L GPVRGISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKE
P08758 S116 Sugiyama ANXA5 ANX5 ENX2 PP4 LKHALKGAGTNEKVLtEIIAsRtPEELRAIKQVyEEEyGss
P08758 T10 Sugiyama ANXA5 ANX5 ENX2 PP4 ___________MAQVLRGtVtDFPGFDERADAEtLRKAMKG
P08758 T8 Sugiyama ANXA5 ANX5 ENX2 PP4 _____________MAQVLRGtVtDFPGFDERADAEtLRKAM
P08865 S75 Sugiyama RPSA LAMBR LAMR1 WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG
P08865 T82 Sugiyama RPSA LAMBR LAMR1 ARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtPIAGR
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09525 S125 Sugiyama ANXA4 ANX4 DEGCLIEILASRTPEEIRRIsQtYQQQYGRSLEDDIRSDTS
P09972 S45 Sugiyama ALDOC ALDC APGKGILAADEsVGsMAKRLsQIGVENtEENRRLYRQVLFs
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DJD0 S1466 Sugiyama RGPD1 RANBP2L6 RGP1 DEAKTAQEKDsLItPHVsRsstPREsPCGKIAVAVLEEtTR
P0DPH7 S48 Sugiyama TUBA3C TUBA2 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P10809 S398 Sugiyama HSPD1 HSP60 LDVttsEyEKEKLNERLAKLsDGVAVLKVGGtsDVEVNEKK
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P10809 T422 Sugiyama HSPD1 HSP60 AVLKVGGtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGC
P10809 Y243 Sugiyama HSPD1 HSP60 yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI
P11047 T332 Sugiyama LAMC1 LAMB2 YGVDCEKCLPFFNDRPWRRAtAEsASECLPCDCNGRsQECy
P11047 Y860 Sugiyama LAMC1 LAMB2 GNCNRLTGECLKCIyNtAGFyCDRCKDGFFGNPLAPNPADK
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11413 S106 Sugiyama G6PD PFFKATPEEKLKLEDFFARNsyVAGQyDDAAsyQRLNsHMN
P11586 S490 Sugiyama MTHFD1 MTHFC MTHFD QTDKALFNRLVPSVNGVRRFsDIQIRRLKRLGIEKTDPTTL
P11586 S870 Sugiyama MTHFD1 MTHFC MTHFD EVYTKQGFGNLPICMAKtHLsLsHNPEQKGVPTGFILPIRD
P11586 T867 Sugiyama MTHFD1 MTHFC MTHFD HKAEVYTKQGFGNLPICMAKtHLsLsHNPEQKGVPTGFILP
P11940 S51 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 FSPAGPILsIRVCRDMITRRsLGyAyVNFQQPADAERALDt
P11940 S96 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 VIKGKPVRIMWSQRDPsLRKsGVGNIFIKNLDKSIDNKALy
P12268 S416 Sugiyama IMPDH2 IMPD2 APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK
P12277 S129 Sugiyama CKB CKBB DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG
P12277 T322 Sugiyama CKB CKBB LGKHEKFsEVLKRLRLQKRGtGGVDtAAVGGVFDVsNADRL
P12277 T327 Sugiyama CKB CKBB KFsEVLKRLRLQKRGtGGVDtAAVGGVFDVsNADRLGFSEV
P12277 Y39 Sugiyama CKB CKBB EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT
P13010 S318 Sugiyama XRCC5 G22P2 NDDDETEVLKEDIIQGFRyGsDIVPFSKVDEEQMKYKSEGK
P13489 S290 Sugiyama RNH1 PRI RNH AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 Y730 Sugiyama EEF2 EF2 HADAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQ
P13667 T449 Sugiyama PDIA4 ERP70 ERP72 AATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLsE
P13667 Y448 Sugiyama PDIA4 ERP70 ERP72 RAATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLs
P13667 Y458 Sugiyama PDIA4 ERP70 ERP72 VLEVAKDFPEytFAIADEEDyAGEVKDLGLsEsGEDVNAAI
P13804 S192 Sugiyama ETFA sFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPEL
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P14314 S126 Sugiyama PRKCSH G19P1 yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14314 T479 Sugiyama PRKCSH G19P1 KFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPSR
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 S346 Sugiyama PKM OIP3 PK2 PK3 PKM2 CAtQMLEsMIKKPRPTRAEGsDVANAVLDGADCIMLSGEtA
P14618 S97 Sugiyama PKM OIP3 PK2 PK3 PKM2 sHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGP
P14618 T45 Sugiyama PKM OIP3 PK2 PK3 PKM2 TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14625 S106 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S172 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 VGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSELI
P14625 S514 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK
P14866 S471 Sugiyama HNRNPL HNRPL P/OKcl.14 VCVSKQPAIMPGQSyGLEDGsCsyKDFSESRNNRFstPEQA
P14866 S539 Sugiyama HNRNPL HNRPL P/OKcl.14 EICDELGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETL
P14866 S542 Sugiyama HNRNPL HNRPL P/OKcl.14 DELGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFL
P14866 S543 Sugiyama HNRNPL HNRPL P/OKcl.14 ELGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLN
P14866 S544 Sugiyama HNRNPL HNRPL P/OKcl.14 LGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLNH
P14868 S190 Sugiyama DARS1 DARS PIG40 GRATVNQDTRLDNRVIDLRTsTsQAVFRLQSGICHLFRETL
P15328 S149 Sugiyama FOLR1 FOLR VLNVPLCKEDCEQWWEDCRTsYTCKSNWHKGWNWTSGFNKC
P15924 S1658 Sugiyama DSP DVLDGHLREKQRTQEELRRLssEVEALRRQLLQEQESVKQA
P16070 S43 Sugiyama CD44 LHR MDU2 MDU3 MIC4 DLNITCRFAGVFHVEKNGRYsIsRtEAADLCKAFNSTLPTM
P16083 S83 Sugiyama NQO2 NMOR2 PEVFNyGVEtHEAyKQRsLAsDITDEQKKVREADLVIFQFP
P16930 S165 Sugiyama FAH ENALMPNWLHLPVGYHGRAssVVVSGTPIRRPMGQMKPDDS
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17066 Y43 Sugiyama HSPA6 HSP70B' FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P17174 S106 Sugiyama GOT1 RLALGDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNG
P17812 S573 Sugiyama CTPS1 CTPS HYLQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD__
P17987 S35 Sugiyama TCP1 CCT1 CCTA EtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTIT
P17987 S374 Sugiyama TCP1 CCT1 CCTA ERICDDELILIKNTKARTsAsIILRGANDFMCDEMERSLHD
P18615 S131 Sugiyama NELFE RD RDBP QRsIsADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGE
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18669 S118 Sugiyama PGAM1 PGAMA CDABP0006 LNKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsK
P18858 S901 Sugiyama LIG1 DKQPEQATTSAQVACLYRKQsQIQNQQGEDsGsDPEDTY__
P19174 S1233 Sugiyama PLCG1 PLC1 PAKENGDLsPFsGtsLRERGsDASGQLFHGRAREGsFEsRy
P19338 S328 Sugiyama NCL NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P20618 S162 Sugiyama PSMB1 PSC5 DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG
P22059 S379 Sugiyama OSBP OSBP1 FFDAPEIITMPENLGHKRtGsNIsGAssDIsLDEQyKHQLE
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P22626 S212 Sugiyama HNRNPA2B1 HNRPA2B1 EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD
P22626 S225 Sugiyama HNRNPA2B1 HNRPA2B1 GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P22626 S231 Sugiyama HNRNPA2B1 HNRPA2B1 DsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyNGyGGGP
P23142 S247 Sugiyama FBLN1 PP213 CRLGESCINTVGSFRCQRDssCGtGYELTEDNSCKDIDECE
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23434 Y139 Sugiyama GCSH EVTEINEALAENPGLVNKSCyEDGWLIKMtLsNPsELDELM
P25205 S447 Sugiyama MCM3 EQGRVTIAKAGIHARLNARCsVLAAANPVyGRyDQyKTPME
P25705 S76 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM EERILGADtsVDLEETGRVLsIGDGIARVHGLRNVQAEEMV
P25786 S211 Sugiyama PSMA1 HC2 NU PROS30 PSC2 GLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDDDDVsP
P25789 T10 Sugiyama PSMA4 HC9 PSC9 ___________MSRRyDsRttIFsPEGRLYQVEYAMEAIGH
P25963 S262 PSP NFKBIA IKBA MAD3 NFKBI DVNRVTYQGYSPYQLTWGRPsTRIQQQLGQLTLENLQMLPE
P25963 S32 EPSD|PSP NFKBIA IKBA MAD3 NFKBI AMEGPRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEI
P25963 S63 PSP NFKBIA IKBA MAD3 NFKBI EQMVKELQEIRLEPQEVPRGsEPWKQQLTEDGDSFLHLAII
P26232 T657 Sugiyama CTNNA2 CAPR EDDsDFEQEDYDVRsRtsVQtEDDQLIAGQsARAIMAQLPQ
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26639 S702 Sugiyama TARS1 TARS ISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAEEE
P26639 T704 Sugiyama TARS1 TARS GTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAEEEF_
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27348 S145 Sugiyama YWHAQ YFRyLAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHP
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27348 T141 Sugiyama YWHAQ MKGDYFRyLAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQ
P27694 S384 Sugiyama RPA1 REPA1 RPA70 DADKFDGSRQPVLAIKGARVsDFGGRsLsVLSsSTIIANPD
P27695 S129 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 QELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDE
P27708 S133 Sugiyama CAD IPGLQGVDTRELTKKLREQGsLLGKLVQNGTEPSSLPFLDP
P27708 S1859 Sugiyama CAD RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP
P28066 S172 Sugiyama PSMA5 QLFHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLK
P28066 S174 Sugiyama PSMA5 FHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEA
P29401 S190 Sugiyama TKT ASIYKLDNLVAILDINRLGQsDPAPLQHQMDIyQKRCEAFG
P29401 S305 Sugiyama TKT LAtPPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQAL
P29401 S473 Sugiyama TKT AtEKAVELAANTKGICFIRTsRPENAIIyNNNEDFQVGQAK
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 S70 Sugiyama EEF1D EF1D IARARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVE
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30086 T51 Sugiyama PEBP1 PBP PEBP GAAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDP
P30153 S146 Sugiyama PPP2R1A AHFVPLVKRLAGGDWFTSRTsACGLFSVCYPRVSSAVKAEL
P30154 S158 Sugiyama PPP2R1B AYFVPLVKRLASGDWFTSRTsACGLFSVCYPRASNAVKAEI
P30533 S242 Sugiyama LRPAP1 A2MRAP TELKEKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWD
P31150 S213 Sugiyama GDI1 GDIL OPHN2 RABGDIA XAP4 RTDDyLDQPCLETVNRIKLYsEsLARYGKsPYLyPLyGLGE
P31327 S898 Sugiyama CPS1 LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS
P31939 S554 Sugiyama ATIC PURH OK/SW-cl.86 VSISSDAFFPFRDNVDRAKRsGVAyIAAPSGsAADKVVIEA
P31943 S54 Sugiyama HNRNPH1 HNRPH HNRPH1 CKIQNGAQGIRFIYTREGRPsGEAFVELEsEDEVKLALKKD
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P32969 S182 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 QQATTVKNKDIRKFLDGIyVsEKGtVQQADE__________
P33316 S120 Sugiyama DUT PsKRARPAEVGGMQLRFARLsEHAtAPTRGsARAAGYDLYS
P33316 Y167 Sugiyama DUT PPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDVGAG
P33993 S409 Sugiyama MCM7 CDC47 MCM2 QLLsyIDRLAPRSQYTTGRGssGVGLTAAVLRDSVSGELTL
P33993 S410 Sugiyama MCM7 CDC47 MCM2 LLsyIDRLAPRSQYTTGRGssGVGLTAAVLRDSVSGELTLE
P33993 S483 Sugiyama MCM7 CDC47 MCM2 EQQTISIAKAGILTTLNARCsILAAANPAyGRYNPRRsLEQ
P33993 S678 Sugiyama MCM7 CDC47 MCM2 ADVIFATVRELVSGGRSVRFsEAEQRCVSRGFTPAQFQAAL
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P34932 S647 Sugiyama HSPA4 APG2 HSPH2 EMRDKLSGEYEKFVSEDDRNsFtLKLEDTENWLyEDGEDQP
P34932 S76 Sugiyama HSPA4 APG2 HSPH2 VISNAKNTVQGFKRFHGRAFsDPFVEAEKSNLAYDIVQLPT
P35221 T658 Sugiyama CTNNA1 LDDsDFEtEDFDVRsRtsVQtEDDQLIAGQsARAIMAQLPQ
P35613 S279 Sugiyama BSG UNQ6505/PRO21383 TDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQy
P35658 S421 Sugiyama NUP214 CAIN CAN KIAA0023 FYMINQNPGVKSLIKTPERLsLEGERQPKsPGstPTTPTSS
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802 S185 Sugiyama TAGLN2 KIAA0120 CDABP0035 NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______
P37837 S13 Sugiyama TALDO1 TAL TALDO TALDOR ________MsssPVKRQRMEsALDQLKQFTTVVADTGDFHA
P38606 S384 Sugiyama ATP6V1A ATP6A1 ATP6V1A1 VPP2 RLAEMPADSGYPAyLGARLAsFYERAGRVKCLGNPEREGSV
P38646 S148 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 YDDPEVQKDIKNVPFKIVRAsNGDAWVEAHGKLYSPSQIGA
P38646 S212 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P39019 Y48 Sugiyama RPS19 LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P40227 T147 Sugiyama CCT6A CCT6 CCTZ KEKALQFLEEVKVSREMDREtLIDVARTSLRTKVHAELADV
P41091 S107 Sugiyama EIF2S3 EIF2G KIYKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLV
P41223 T111 Sugiyama BUD31 EDG2 KWKKQGYENLCCLRCIQTRDtNFGtNCICRVPKSKLEVGRI
P41567 T46 Sugiyama EIF1 SUI1 GTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKKK
P42566 S368 Sugiyama EPS15 AF1P EKNNVEQDLKEKEDTIKQRtsEVQDLQDEVQRENTNLQKLQ
P42677 T74 Sugiyama RPS27 MPS1 VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
P43121 S93 Sugiyama MCAM MUC18 IFRVRQGQGQSEPGEYEQRLsLQDRGAtLALtQVtPQDERI
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P43243 S195 Sugiyama MATR3 KIAA0723 RDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyD
P43243 S211 Sugiyama MATR3 KIAA0723 DRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDDRLRDGERCR
P43243 S234 Sugiyama MATR3 KIAA0723 yDRMDyEDDRLRDGERCRDDsFFGEtsHNyHKFDsEyERMG
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P45974 S783 Sugiyama USP5 ISOT IDDLDAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQL
P45974 Y853 Sugiyama USP5 ISOT NDQKVCASEKPPKDLGyIyFyQRVAS_______________
P46013 S648 Sugiyama MKI67 RVSISRsQHDILQMICSKRRsGAsEANLIVAKSWADVVKLG
P46459 S207 Sugiyama NSF KAENSSLNLIGKAKTKENRQsIINPDWNFEKMGIGGLDKEF
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46779 S115 Sugiyama RPL28 HMIRKNKYRPDLRMAAIRRAsAILRSQKPVMVKRKRTRPTK
P47712 S178 Sugiyama PLA2G4A CPLA2 PLA2G4 RQQRKEHIRESMKKLLGPKNsEGLHSARDVPVVAILGSGGG
P47712 S724 Sugiyama PLA2G4A CPLA2 PLA2G4 NIDVIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFL
P47712 S727 Sugiyama PLA2G4A CPLA2 PLA2G4 VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP
P47712 S729 Sugiyama PLA2G4A CPLA2 PLA2G4 KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P48637 S276 Sugiyama GSS VDGQEIAVVYFRDGYMPRQYsLQNWEARLLLERSHAAKCPD
P48643 S51 Sugiyama CCT5 CCTE KIAA0098 LEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtVT
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P48741 Y43 Sugiyama HSPA7 HSP70B FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P49327 S1997 Sugiyama FASN FAS DGLLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFV
P49327 S519 Sugiyama FASN FAS MGTQWRGMGLSLMRLDRFRDsILRsDEAVKPFGLKVSQLLL
P49589 S312 Sugiyama CARS1 CARS GDQKALQEGEGDLsIsADRLsEKRSPNDFALWKASKPGEPS
P49736 S187 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 MIEsIENLEDLKGHSVREWVsMAGPRLEIHHRFKNFLRTHV
P49736 S229 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 sHGHNVFKERIsDMCKENREsLVVNyEDLAAREHVLAYFLP
P49792 S2457 Sugiyama RANBP2 NUP358 DEAKTAQEKDsLItPHVsRsstPREsPCGKIAVAVLEEtTR
P49792 T1098 Sugiyama RANBP2 NUP358 GDGYsGAKPIPGGQTIGPRNtFNFGSKNVsGIsFtENMGss
P50213 S207 Sugiyama IDH3A ARNNHRSNVTAVHKANIMRMsDGLFLQKCREVAESCKDIKF
P50395 S213 Sugiyama GDI2 RABGDIB RtDDyLDQPCyEtINRIKLYsEsLARYGKsPYLyPLyGLGE
P50395 S396 Sugiyama GDI2 RABGDIB IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD
P50395 S427 Sugiyama GDI2 RABGDIB ttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED__
P50395 T425 Sugiyama GDI2 RABGDIB DAttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED
P50991 S51 Sugiyama CCT4 CCTD SRB AQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtIt
P51116 S601 Sugiyama FXR2 FMR1L2 RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ
P51153 S155 Sugiyama RAB13 GIG4 QADKLAREHGIRFFETSAKSsMNVDEAFSsLARDILLKSGG
P51570 S230 Sugiyama GALK1 GALK LVPLSDPKLAVLITNSNVRHsLASSEYPVRRRQCEEVARAL
P51617 S591 Sugiyama IRAK1 IRAK sAQAAEQLQRGPNQPVEsDEsLGGLsAALRsWHLtPsCPLD
P51813 Y360 Sugiyama BMX NDKKGTVKHYHVHTNAENKLyLAENyCFDsIPKLIHyHQHN
P51813 Y365 Sugiyama BMX TVKHYHVHTNAENKLyLAENyCFDsIPKLIHyHQHNsAGMI
P51813 Y90 Sugiyama BMX EQtPVERQyPFQIVyKDGLLyVyASNEESRSQWLKALQKEI
P51813 Y92 Sugiyama BMX tPVERQyPFQIVyKDGLLyVyASNEESRSQWLKALQKEIRG
P51858 S83 Sugiyama HDGF HMG1L2 LFPyEEsKEKFGKPNKRKGFsEGLWEIENNPtVKASGYQSs
P51991 S350 Sugiyama HNRNPA3 HNRPA3 NDFGNYSGQQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGs
P51991 S355 Sugiyama HNRNPA3 HNRPA3 YSGQQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGs
P51991 S358 Sugiyama HNRNPA3 HNRPA3 QQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF
P52209 S126 Sugiyama PGD PGDH YRDTTRRCRDLKAKGILFVGsGVsGGEEGARyGPSLMPGGN
P52597 S54 Sugiyama HNRNPF HNRPF CtIHDGAAGVHFIYTREGRQsGEAFVELGsEDDVKMALKKD
P52789 S408 Sugiyama HK2 ATLAAVLQRIKENKGEERLRstIGVDGsVyKKHPHFAKRLH
P52789 T409 Sugiyama HK2 TLAAVLQRIKENKGEERLRstIGVDGsVyKKHPHFAKRLHK
P52907 S123 Sugiyama CAPZA1 KEAsDPQPEEADGGLKsWREsCDsALRAYVKDHYSNGFCTV
P53041 S403 Sugiyama PPP5C PPP5 DLLWSDPQPQNGRSISKRGVsCQFGPDVTKAFLEENNLDyI
P53396 S455 Sugiyama ACLY ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP
P53396 S656 Sugiyama ACLY IGNTGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISR
P54578 S431 Sugiyama USP14 TGT GSNNCGYYDLQAVLTHQGRSssSGHyVSWVKRKQDEWIKFD
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55010 S10 Sugiyama EIF5 ___________MSVNVNRsVsDQFyRyKMPRLIAKVEGKGN
P55084 S284 Sugiyama HADHB MSTP029 VVPFKVPGKDTVTKDNGIRPsSLEQMAKLKPAFIKPYGTVT
P56537 S6 Sugiyama EIF6 EIF3A ITGB4BP OK/SW-cl.27 _______________MAVRAsFENNCEIGCFAKLTNTYCLV
P56937 S337 Sugiyama HSD17B7 17HSD7 SDR37C1 UNQ2563/PRO6243 LELEKHIRVTIQKTDNQARLsGsCL________________
P57053 S37 Sugiyama H2BC12L H2BFS H2BS1 KAVTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIss
P57721 S158 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT AsQCGsLIGKGGSKIKEIREstGAQVQVAGDMLPNstERAV
P57721 S59 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT EGGLNVTLTIRLLMHGKEVGsIIGKKGETVKKMREESGARI
P57721 S82 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK
P57721 T159 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT sQCGsLIGKGGSKIKEIREstGAQVQVAGDMLPNstERAVT
P57723 S31 Sugiyama PCBP4 EPELSITLTLRMLMHGKEVGsIIGKKGETVKRIREQSSARI
P58876 S37 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60228 S442 Sugiyama EIF3E EIF3S6 INT6 IEKKLNQNSRSEAPNWAtQDsGFy_________________
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S239 Sugiyama ACTB VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P61081 S175 Sugiyama UBE2M UBC12 NNRRLFEQNVQRSMRGGyIGstyFERCLK____________
P61163 S331 Sugiyama ACTR1A CTRN1 GDRLLSEVKKLAPKDVKIRIsAPQERLYSTWIGGSILASLD
P61353 S86 Sugiyama RPL27 SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL
P61764 S469 Sugiyama STXBP1 UNC18A PIVTDSTLRRRSKPERKERIsEQTyQLSRWTPIIKDIMEDT
P61764 S507 Sugiyama STXBP1 UNC18A EDTIEDKLDTKHYPYISTRssAsFSTTAVsARYGHWHKNKA
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61978 T39 Sugiyama HNRNPK HNRPK FGKRPAEDMEEEQAFKRsRNtDEMVELRILLQSKNAGAVIG
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62701 T247 Sugiyama RPS4X CCG2 RPS4 SCAR VIGKGNKPWIsLPRGKGIRLtIAEERDKRLAAKQSSG____
P62736 S241 Sugiyama ACTA2 ACTSA ACTVS GIG46 VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62753 S53 Sugiyama RPS6 OK/SW-cl.2 AtEVAADALGEEWKGYVVRIsGGNDKQGFPMKQGVLTHGRV
P62807 S37 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI KAVTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIss
P62826 T32 Sugiyama RAN ARA24 OK/SW-cl.81 KLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGVEVHPLVF
P62906 S64 Sugiyama RPL10A NEDD6 QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63146 S142 Sugiyama UBE2B RAD6B UBCH1 ANSQAAQLYQENKREYEKRVsAIVEQsWNDS__________
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S239 Sugiyama ACTG1 ACTG VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63267 S240 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67809 S209 Sugiyama YBX1 NSEP1 YB1 RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ
P67809 Y208 Sugiyama YBX1 NSEP1 YB1 yRRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGE
P68032 S241 Sugiyama ACTC1 ACTC VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S241 Sugiyama ACTA1 ACTA VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 S48 Sugiyama TUBA1B HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363 Y432 Sugiyama TUBA1B GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
P68431 S11 SIGNOR|EPSD H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J __________MARtKQtARKstGGKAPRKQLATKAARKsAP
P68431 S29 EPSD H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J RKstGGKAPRKQLATKAARKsAPATGGVKKPHRyRPGtVAL
P78371 S470 Sugiyama CCT2 99D8.1 CCTB IADNAGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAI
P78371 S60 Sugiyama CCT2 99D8.1 CCTB KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P98082 S723 Sugiyama DAB2 DOC2 DANQLLNKINEPPKPAPRQVsLPVTKstDNAFENPFFKDsF
Q00610 S146 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 AVYHWSMEGESQPVKMFDRHssLAGCQIINYRTDAKQKWLL
Q00610 S147 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 VYHWSMEGESQPVKMFDRHssLAGCQIINYRTDAKQKWLLL
Q00610 S1483 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 VNEsLNNLFITEEDyQALRTsIDAyDNFDNIsLAQRLEKHE
Q00610 S576 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 YNLIQQCTAFLLDALKNNRPsEGPLQTRLLEMNLMHAPQVA
Q00610 S751 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 YIQAACKTGQIKEVERICREsNCyDPERVKNFLKEAKLTDQ
Q01082 S2074 Sugiyama SPTBN1 SPTB2 KLIKRHEAFEKSAATWDERFsALERLTTLELLEVRRQQEEE
Q01082 S825 Sugiyama SPTBN1 SPTB2 EQASALPQEHAEsPDVRGRLsGIEERYKEVAELTRLRKQAL
Q02790 T278 Sugiyama FKBP4 FKBP52 sWEMNsEEKLEQSTIVKERGtVYFKEGKYKQALLQYKKIVS
Q02818 S369 Sugiyama NUCB1 NUC RFEEELAAREAELNAKAQRLsQETEALGRsQGRLEAQKREL
Q04446 S75 Sugiyama GBE1 ILKNIGENEGGIDKFSRGyEsFGVHRCADGGLYCKEWAPGA
Q04637 S1199 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI TPATKRsFsKEVEERsRERPsQPEGLRKAAsLtEDRDRGRD
Q04695 S28 Sugiyama KRT17 FTSSSsIKGSSGLGGGsSRTsCRLsGGLGAGsCRLGSAGGL
Q04695 S32 Sugiyama KRT17 SsIKGSSGLGGGsSRTsCRLsGGLGAGsCRLGSAGGLGSTL
Q04726 S196 Sugiyama TLE3 KIAA1547 AHLTVKDEKNHHELDHREREssANNsVsPsEsLRAsEKHRG
Q04726 S197 Sugiyama TLE3 KIAA1547 HLTVKDEKNHHELDHREREssANNsVsPsEsLRAsEKHRGs
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06210 T263 Sugiyama GFPT1 GFAT GFPT QGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDASA
Q06830 S32 Sugiyama PRDX1 PAGA PAGB TDPX2 APNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTFVC
Q07021 S106 Sugiyama C1QBP GC1QBP HABP1 SF2P32 LsDEIKEERKIQKHKTLPKMsGGWELELNGTEAKLVRKVAG
Q07021 S210 Sugiyama C1QBP GC1QBP HABP1 SF2P32 EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS
Q07666 S20 Sugiyama KHDRBS1 SAM68 _MQRRDDPAARMsRssGRsGsMDPsGAHPsVRQtPsRQPPL
Q07866 S524 Sugiyama KLC1 KLC KNS2 QRVAEVLNDPENMEKRRsREsLNVDVVKYESGPDGGEEVSM
Q08211 S449 Sugiyama DHX9 DDX9 LKP NDH2 FIQNDRAAECNIVVTQPRRIsAVsVAERVAFERGEEPGKSC
Q08211 S452 Sugiyama DHX9 DDX9 LKP NDH2 NDRAAECNIVVTQPRRIsAVsVAERVAFERGEEPGKSCGYS
Q08211 S623 Sugiyama DHX9 DDX9 LKP NDH2 DDDANCNLICGDEyGPETRLsMsQLNEKETPFELIEALLKY
Q08378 S465 Sugiyama GOLGA3 LSTKLQAQVECSHSSQQRQDsLsSEVDTLKQsCWDLERAMT
Q09028 S147 Sugiyama RBBP4 RBAP48 VNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGEC
Q09161 S22 Sugiyama NCBP1 CBP80 NCBP SRRRHsDENDGGQPHKRRKtsDANEtEDHLEsLICKVGEKS
Q13085 S1762 Sugiyama ACACA ACAC ACC1 ACCA EDPYKGYRYLYLTPQDYKRVsALNsVHCEHVEDEGESRYKI
Q13098 S240 Sugiyama GPS1 COPS1 CSN1 SYVSKAESTPEIAEQRGERDsQtQAILTKLKCAAGLAELAA
Q13098 T242 Sugiyama GPS1 COPS1 CSN1 VSKAESTPEIAEQRGERDsQtQAILTKLKCAAGLAELAARK
Q13162 S68 Sugiyama PRDX4 EEECHFyAGGQVyPGEAsRVsVADHsLHLSKAKISKPAPYW
Q13263 S479 Sugiyama TRIM28 KAP1 RNF96 TIF1B ssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLERLDLDLtA
Q13263 T415 Sugiyama TRIM28 KAP1 RNF96 TIF1B LNAWTKSAEAFGKIVAERPGtNstGPAPMAPPRAPGPLSKQ
Q13283 S67 Sugiyama G3BP1 G3BP sNGKPADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLN
Q13310 S51 Sugiyama PABPC4 APP1 PABP4 FSPAGPVLsIRVCRDMITRRsLGyAyVNFQQPADAERALDt
Q13310 S96 Sugiyama PABPC4 APP1 PABP4 VIKGKPIRIMWSQRDPsLRKsGVGNVFIKNLDKSIDNKALy
Q13501 S24 Sugiyama SQSTM1 ORCA OSIL LTVKAYLLGKEDAAREIRRFsFCCsPEPEAEAEAAAGPGPC
Q13547 S434 Sugiyama HDAC1 RPD3L1 IACEEEFsDsEEEGEGGRKNsSNFKKAKRVKTEDEKEKDPE
Q13610 S484 Sugiyama PWP1 SSVNEAFGRRERLVLGSARNssISGPFGsRssDTPMES___
Q13610 S485 Sugiyama PWP1 SVNEAFGRRERLVLGSARNssISGPFGsRssDTPMES____
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S1262 Sugiyama EIF3A EIF3S10 KIAA0139 PRDEGGWRRGPAEEsssWRDssRRDDRDRDDRRRERDDRRD
Q14152 S492 Sugiyama EIF3A EIF3S10 KIAA0139 VDAARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQ
Q14152 S895 Sugiyama EIF3A EIF3S10 KIAA0139 ERRLGDssLSRKDSRWGDRDsEGtWRKGPEADsEWRRGPPE
Q14157 S852 Sugiyama UBAP2L KIAA0144 NICE4 LDyysIPFPtPttPLtGRDGsLAsNPysGDLtKFGRGDASS
Q14204 T1255 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 QVANLQMKIVQEDRAVESRTtDLLTDWEKTKPVTGNLRPEE
Q14498 S333 Sugiyama RBM39 HCC1 RNPC2 GFELAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGt
Q14566 S271 Sugiyama MCM6 VPDVSKLSTPGARAEtNsRVsGVDGyEtEGIRGLRALGVRD
Q14566 S498 Sugiyama MCM6 EQQTISITKAGVKATLNARTsILAAANPIsGHyDRSKSLKQ
Q14568 S164 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGT
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14568 S50 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14568 T171 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 ITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILHLK
Q14568 Y283 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI
Q14669 S1054 Sugiyama TRIP12 KIAA0045 ULF TQsPKSSFLASLNPKTWGRLstQsNSNNIEPARTAGGSGLA
Q14671 S709 Sugiyama PUM1 KIAA0099 PUMH1 LGGFGTAVANSNTGSGSRRDsLtGSsDLYKRTSSSLTPIGH
Q14677 S166 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14677 Y172 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 AKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDEEWDKNK
Q14697 S190 Sugiyama GANAB G2AN KIAA0088 VNARGLLEFEHQRAPRVsQGsKDPAEGDGAQPEEtPRDGDK
Q15021 S585 Sugiyama NCAPD2 CAPD2 CNAP1 KIAA0159 ILGLIFKGPAASTQEKNPREstGNMVTGQTVCKNKPNMsDP
Q15021 T586 Sugiyama NCAPD2 CAPD2 CNAP1 KIAA0159 LGLIFKGPAASTQEKNPREstGNMVTGQTVCKNKPNMsDPE
Q15084 S156 Sugiyama PDIA6 ERP5 P5 TXNDC7 KDRLGGRSGGYSSGKQGRSDsSSKKDVIELtDDsFDKNVLD
Q15084 S389 Sugiyama PDIA6 ERP5 P5 TXNDC7 FALLKGsFsEQGINEFLRELsFGRGstAPVGGGAFPtIVER
Q15084 S394 Sugiyama PDIA6 ERP5 P5 TXNDC7 GsFsEQGINEFLRELsFGRGstAPVGGGAFPtIVEREPWDG
Q15084 S88 Sugiyama PDIA6 ERP5 P5 TXNDC7 AATALKDVVKVGAVDADKHHsLGGQyGVQGFPtIKIFGSNK
Q15084 T395 Sugiyama PDIA6 ERP5 P5 TXNDC7 sFsEQGINEFLRELsFGRGstAPVGGGAFPtIVEREPWDGR
Q15185 S72 Sugiyama PTGES3 P23 TEBP EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE
Q15185 S85 Sugiyama PTGES3 P23 TEBP KHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVDFNN
Q15365 S126 Sugiyama PCBP1 ATQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAI
Q15365 S27 Sugiyama PCBP1 ESGLNVTLTIRLLMHGKEVGsIIGKKGESVKRIREEsGARI
Q15365 S50 Sugiyama PCBP1 GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK
Q15365 T127 Sugiyama PCBP1 TQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT
Q15366 S126 Sugiyama PCBP2 AsQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAI
Q15366 S27 Sugiyama PCBP2 EGGLNVTLTIRLLMHGKEVGsIIGKKGESVKKMREESGARI
Q15366 S50 Sugiyama PCBP2 GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK
Q15366 T127 Sugiyama PCBP2 sQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT
Q16576 S146 Sugiyama RBBP7 RBAP46 VNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGEC
Q16658 S120 Sugiyama FSCN1 FAN1 HSN SNL RWSLQSEAHRRYFGGtEDRLsCFAQtVsPAEKWSVHIAMHP
Q4VXU2 S96 Sugiyama PABPC1L C20orf119 MLKGQPIRIMWSQRDPGLRKsGVGNIFIKNLEDSIDNKALY
Q562R1 S240 Sugiyama ACTBL2 VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF6 S34 Sugiyama HSP90AB4P IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN
Q58FF7 S58 Sugiyama HSP90AB3P HSP90BC IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8 S58 Sugiyama HSP90AB2P HSP90BB IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8 Y198 Sugiyama HSP90AB2P HSP90BB DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI
Q5JQF8 S87 Sugiyama PABPC1L2A PABPC1L2 RBM32A; PABPC1L2B PABPC1L2 RBM32B VIKGRPVRIMWSQRDPsLRKsGVGNVFIKNLGKTIDNKALY
Q5JTD0 S545 Sugiyama TJAP1 PILT TJP4 ssRPQRsPKRMGVHHLHRKDsLtQAQEQGNLLN________
Q5QNW6 S37 Sugiyama H2BC18 HIST2H2BF KAVTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q5T1M5 S1162 Sugiyama FKBP15 KIAA0674 EAGstVAGAALRPsHHsQRssLsGDEEDELFKGATLKALRP
Q5T4S7 S1752 Sugiyama UBR4 KIAA0462 KIAA1307 RBAF600 PssGMsSTMKESAFQsEPRIsESLVRHAstssPADKAKVTI
Q5T4S7 S3846 Sugiyama UBR4 KIAA0462 KIAA1307 RBAF600 KELLEYDLQQREAATKSSRTsVQPTFTASQyRALsVLGCGH
Q5T5C0 S692 Sugiyama STXBP5 LLGL3 YGSNDPYRREPRSPRKsRQPsGAGLCDIsEGtVVPEDRCKS
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q6GYQ0 S797 Sugiyama RALGAPA1 GARNL1 KIAA0884 TULIP1 EtGNEVFGALNEEQPLPRssstsDILEPFTVERAKVNKEDM
Q6GYQ0 S864 Sugiyama RALGAPA1 GARNL1 KIAA0884 TULIP1 AERLRSGNASTMTRRGssPGsLEIPKDLPDILNKQNQMRPI
Q6PEY2 S48 Sugiyama TUBA3E HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PIW4 S616 Sugiyama FIGNL1 IVQQSDAFSGADMTQLCREAsLGPIRSLQTADIATITPDQV
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 S939 Sugiyama POTEE A26C1A POTE2 VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6UVK1 S321 Sugiyama CSPG4 MCSP DQYPTHTSNRGVLSYLEPRGsLLLGGLDAEASRHLQEHRLG
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71U36 S48 Sugiyama TUBA1A TUBA3 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36 Y432 Sugiyama TUBA1A TUBA3 GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
Q71UM5 T74 Sugiyama RPS27L VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
Q7KZF4 S150 Sugiyama SND1 TDRD11 EGLAtRREGMRANNPEQNRLsECEEQAKAAKKGMWSEGNGS
Q7Z3J3 S1482 Sugiyama RGPD4 RGP4 DEAKTAQEKDsLItPHVsRsstPREsPCGKIAVAVLEEtTR
Q7Z417 S652 Sugiyama NUFIP2 KIAA1321 PIG1 NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI
Q7Z460 S253 Sugiyama CLASP1 KIAA0622 MAST1 IQSANDKNFDDEDsVDGNRPssAsStSSKAPPSSRRNVGMG
Q7Z5L9 S457 Sugiyama IRF2BP2 GSHASKDANQVHSTTRRNsNsPPsPssMNQRRLGPREVGGQ
Q86V81 S145 Sugiyama ALYREF ALY BEF THOC4 LFAEFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQ
Q86VQ1 S223 Sugiyama GLCCI1 QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR
Q8IZ83 S427 Sugiyama ALDH16A1 SPFRTAKEALLVANGtPRGGsASVWSERLGQALELGYGLQV
Q8IZ83 S550 Sugiyama ALDH16A1 LFVGGRFQAPGARSSRPIRDssGNLHGYVAEGGAKDIRGAV
Q8N0Y7 S118 Sugiyama PGAM4 PGAM3 LNKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsK
Q8N6H7 S123 Sugiyama ARFGAP2 ZNF289 Nbla10535 NTKYNSRAAQMYREKIRQLGsAALARHGTDLWIDNMssAVP
Q8NBJ5 S607 Sugiyama COLGALT1 GLT25D1 PSEC0241 DRAKSQKMREQQALSREAKNsDVLQsPLDsAARDEL_____
Q8NBJ7 S256 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG
Q8NBP7 S595 Sugiyama PCSK9 NARC1 PSEC0052 KPPVLRPRGQPNQCVGHREAsIHASCCHAPGLECKVKEHGI
Q8NFD5 S1744 Sugiyama ARID1B BAF250B DAN15 KIAA1235 OSA2 ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI
Q8NHP8 S201 Sugiyama PLBD2 QVRLTLLQLKGLEDSYEGRVsFPAGKFTIKPLGFLLLQLSG
Q8TCS8 S768 Sugiyama PNPT1 PNPASE SRKVLQsPAtTVVRTLNDRssIVMGEPIsQSSSNsQ_____
Q8TD19 S332 Sugiyama NEK9 KIAA1995 NEK8 NERCC RREMEEKVTLLNAPTKRPRsstVtEAPIAVVTSRTSEVYVW
Q8TD47 T247 Sugiyama RPS4Y2 RPS4Y2P VIGNGNKPWISLPRGKGIRLtIAEERDKRLAAKQSSG____
Q8TEW0 S962 Sugiyama PARD3 PAR3 PAR3A DEGMEtLEEDTEESSRsGREsVstAsDQPsHsLERQMNGNQ
Q8WW59 S113 Sugiyama SPRYD4 TVKRSQQFRIGVADVDMSRDsCIGVDDRSWVFTYAQRKWYT
Q8WWM7 S273 Sugiyama ATXN2L A2D A2LG A2LP A2RP PNEMFKFNEENyGVKTtyDssLssytVPLEKDNsEEFRQRE
Q8WWM7 S500 Sugiyama ATXN2L A2D A2LG A2LP A2RP VTSSVSDPGVGsIsPAsPKIsLAPTDVKELSTKEPGRTLEP
Q8WX93 S1352 Sugiyama PALLD KIAA0992 CGI-151 QsQstKPKKVRPSASRyAALsDQGLDIKAAFQPEANPSHLT
Q92547 S998 Sugiyama TOPBP1 KIAA0259 AQECKHLPESLYPHTYNPKMsLDIsAVQDGRLCNSRLLSAV
Q92597 S332 Sugiyama NDRG1 CAP43 DRG1 RTP MGYMPsAsMtRLMRsRtAsGssVtsLDGtRsRsHtSEGTRs
Q92609 S732 Sugiyama TBC1D5 KIAA0210 sDDFILISKDDDGssARGsFsGQAQPLRtLRSTSGKSQAPV
Q93079 S37 Sugiyama H2BC9 H2BFJ HIST1H2BH KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q969S3 S38 Sugiyama ZNF622 ZPR9 MQRAHYKTDWHRYNLRRKVAsMAPVTAEGFQERVRAQRAVA
Q96D15 S117 Sugiyama RCN3 UNQ239/PRO272 VsLAELRAWIAHTQQRHIRDsVsAAWDtyDtDRDGRVGWEE
Q96D46 S462 Sugiyama NMD3 CGI-07 FLEDLEEDEAIRKNVNIyRDsAIPVEsDtDDEGAPRISLAE
Q96DU9 S103 Sugiyama PABPC5 PABP5 LINGKPFRLMWSQPDDRLRKsGVGNIFIKNLDKSIDNRALF
Q96G46 T240 Sugiyama DUS3L KREVRFERAEQALRRFsQGPtPAAAVPEGTAAEGAPRQENC
Q96GD4 Y92 Sugiyama AURKB AIK2 AIM1 AIRK2 ARK2 STK1 STK12 STK5 FtIDDFEIGRPLGKGKFGNVyLAREKKSHFIVALKVLFKSQ
Q96HE7 S143 Sugiyama ERO1A ERO1L UNQ434/PRO865 EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD
Q96K76 S917 Sugiyama USP47 sKstEtsDFENIEsPLNERDsSAsVDNRELEQHIQtsDPEN
Q96RS6 S373 Sugiyama NUDCD1 CML66 EGLTWPELVIGDKQGELIRDsAQCAAIAERLMHLtsEELNP
Q99584 S32 Sugiyama S100A13 SIETVVTTFFTFARQEGRKDsLsVNEFKELVTQQLPHLLKD
Q99666 S1481 Sugiyama RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6 DEAKTAQEKDsLItPHVsRsstPREsPCGKIAVAILEETTR
Q99877 S37 Sugiyama H2BC15 H2BFD HIST1H2BN KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q99879 S37 Sugiyama H2BC14 H2BFE HIST1H2BM KAINKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q99880 S37 Sugiyama H2BC13 H2BFC HIST1H2BL KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q9BQE3 S48 Sugiyama TUBA1C TUBA6 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BYX7 S239 Sugiyama POTEKP ACTBL3 FKSG30 VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9C0C2 S1383 Sugiyama TNKS1BP1 KIAA1741 TAB182 REHGVGGVsQCPEPGLRHNGsLsPGLEARDPLEARELGVGE
Q9C0C2 S1533 Sugiyama TNKS1BP1 KIAA1741 TAB182 GEAsQTEDVDGTWGSSAARWsDQGPAQTSRRPsQGPPARsP
Q9C0C2 S1616 Sugiyama TNKS1BP1 KIAA1741 TAB182 LSEAADsDAHLFQDSTEPRAsRVPssDEEVVEEPQsRRTRM
Q9C0C2 S936 Sugiyama TNKS1BP1 KIAA1741 TAB182 GRyssQDADEQDWEFQKRDVsLGTyGSRAAEPQEQEFGKSA
Q9C0C2 S962 Sugiyama TNKS1BP1 KIAA1741 TAB182 SRAAEPQEQEFGKSAWIRDyssGGsSRtLDAQDRsFGtRPL
Q9H0B6 S428 Sugiyama KLC2 NKPIWMHAEEREESKDKRRDsAPyGEyGsWYKACKVDsPtV
Q9H0D6 S678 Sugiyama XRN2 LRAALEEVyPDLTPEEtRRNsLGGDVLFVGKHHPLHDFILE
Q9H2G2 S340 Sugiyama SLK KIAA0204 STK2 EEDEEEEtENsLPIPAsKRAssDLsIAssEEDKLsQNACIL
Q9H3N1 S270 Sugiyama TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 EAEsKEGtNKDFPQNAIRQRsLGPsLAtDKs__________
Q9H3Q1 S309 Sugiyama CDC42EP4 BORG4 CEP4 AAPsPGsARSMGSHTTRDSSsLssCtsGILEERsPAFRGPD
Q9H7D7 S121 Sugiyama WDR26 CDW2 MIP2 PRO0852 ASSSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLN
Q9H814 S149 Sugiyama PHAX RNUXA AVATELGILGMEGTIDRsRQsEtyNyLLAKKLRKESQEHTK
Q9HA65 S366 Sugiyama TBC1D17 EYFRMKLQWKSVSPEQERRNsLLHGYRSLIERDVSRTDRTN
Q9NQS7 S893 EPSD|PSP INCENP LPLDLEDIFKKSKPRYHKRtssAVWNsPPLQGARVPssLAY
Q9NQS7 S894 EPSD|PSP INCENP PLDLEDIFKKSKPRYHKRtssAVWNsPPLQGARVPssLAYs
Q9NQS7 T892 EPSD|PSP INCENP ILPLDLEDIFKKSKPRYHKRtssAVWNsPPLQGARVPssLA
Q9NQX3 S262 Sugiyama GPHN GPH KIAA1385 AKIPDSIISRGVQVLPRDTAsLsttPsEsPRAQAtsRLstA
Q9NQX3 S280 Sugiyama GPHN GPH KIAA1385 TAsLsttPsEsPRAQAtsRLstAsCPtPKVQSRCSsKENIL
Q9NR45 S253 Sugiyama NANS SAS KVLERHITLDKTWKGsDHsAsLEPGELAELVRSVRLVERAL
Q9NRA8 S353 Sugiyama EIF4ENIF1 SASRFSRWFSNPsRsGsRsssLGstPHEELERLAGLEQAIL
Q9NRX4 S80 Sugiyama PHPT1 PHP14 CGI-202 HSPC141 VSGDMQKQGCDCECLGGGRIsHQSQDKKIHVyGysMAyGPA
Q9NXH9 S514 Sugiyama TRMT1 ALWDIMRCWEKECPVKRERLsETsPAFRILsVEPRLQANFT
Q9NZB2 S30 Sugiyama FAM120A C9orf10 KIAA0183 OSSA IEKHCPsAVVPVELQKLARGsLVGGGRQRPPQTPLRLLVDA
Q9NZL9 S9 Sugiyama MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 ____________MVGREKELsIHFVPGsCRLVEEEVNIPNR
Q9NZN8 S242 Sugiyama CNOT2 CDC36 NOT2 HSPC131 MSTP046 VTGLDLSDFPALADRNRREGsGNPtPLINPLAGRAPYVGMV
Q9UBC2 S374 Sugiyama EPS15L1 EPS15R LsPDMVPPsERGtPGPDssGsLGsGEFTGVKELDDISQEIA
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UBU9 S431 Sugiyama NXF1 TAP HDGACCSLSIPFIPQNPARSsLAEyFKDSRNVKKLKDPTLR
Q9UGV2 S331 Sugiyama NDRG3 QGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQ
Q9UGV2 S334 Sugiyama NDRG3 GYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsDG
Q9UGV2 S335 Sugiyama NDRG3 YIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsDGt
Q9UHD1 S200 Sugiyama CHORDC1 CHP1 SGVPIFHEGMKYWSCCRRKtsDFNtFLAQEGCtKGKHMWTK
Q9UI15 S185 Sugiyama TAGLN3 NP25 EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______
Q9ULD2 S1224 Sugiyama MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 tEQAVLQESLEKESKVNKRLsMENEELLWKLHNGDLCsPKR
Q9ULD2 S1259 Sugiyama MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 LCsPKRsPtssAIPLQsPRNsGsFPsPsIsPR_________
Q9ULT8 S1571 Sugiyama HECTD1 KIAA1131 RVANIARTNAtNNMNLsRsssDNNTNtLGRNVMSTATSPLM
Q9ULX3 S390 Sugiyama NOB1 ART4 NOB1P PSMD8BP1 MSTP158 VsPFVENDISSRSATLQVRDsTLGAGRRRLNPNASRKKFVK
Q9UNH7 S55 Sugiyama SNX6 DISDALSERDKVKFTVHTKSsLPNFKQNEFSVVRQHEEFIW
Q9UNN5 S518 Sugiyama FAF1 UBXD12 UBXN3A CGI-03 EDEREARENVKREQDEAyRLsLEADRAKREAHEREMAEQFR
Q9UNZ2 T73 Sugiyama NSFL1C UBXN2C ISQATPssVsRGTAPSDNRVtsFRDLIHDQDEDEEEEEGQR
Q9UPQ0 S190 Sugiyama LIMCH1 KIAA1102 PKRSIRDsGyIDCWDsERsDsLsPPRHGRDDsFDsLDsFGs
Q9UPQ0 S201 Sugiyama LIMCH1 KIAA1102 DCWDsERsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVV
Q9UPQ0 S207 Sugiyama LIMCH1 KIAA1102 RsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVVLRGssD
Q9UPQ0 Y179 Sugiyama LIMCH1 KIAA1102 QMRKDTDDIEsPKRSIRDsGyIDCWDsERsDsLsPPRHGRD
Q9UPU5 S1685 Sugiyama USP24 KIAA1057 QPDPALTKEFDYLPPVDSRSssGFVGLRNGGATCYMNAVFQ
Q9UPU5 S1686 Sugiyama USP24 KIAA1057 PDPALTKEFDYLPPVDSRSssGFVGLRNGGATCYMNAVFQQ
Q9UPU5 S88 Sugiyama USP24 KIAA1057 GGPRGDGGGDGGGGGPsRGGstGGGGGFDPPPAYHEVVDAE
Q9UQB9 Y58 Sugiyama AURKC AIE2 AIK3 AIRK3 ARK3 STK13 LTVDDFEIGRPLGKGKFGNVyLARLKESHFIVALKVLFKSQ
Q9Y230 S43 Sugiyama RUVBL2 INO80J TIP48 TIP49B CGI-46 GAHSHIRGLGLDDALEPRQAsQGMVGQLAARRAAGVVLEMI
Q9Y262 S80 Sugiyama EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 HKTVSDLIDQKVYELQASRVssDVIDQKVyEIQDIyENSWT
Q9Y262 S81 Sugiyama EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 KTVSDLIDQKVYELQASRVssDVIDQKVyEIQDIyENSWTK
Q9Y2I7 S307 Sugiyama PIKFYVE KIAA0981 PIP5K3 TRLVSVQEDAGKsPARNRsAsItNLsLDRsGsPMVPSYEts
Q9Y2U5 S239 Sugiyama MAP3K2 MAPKKK2 MEKK2 SLDSPLDGESYPKSRMPRAQsyPDNHQEFSDyDNPIFEKFG
Q9Y5L4 S57 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW
Q9Y696 S31 Sugiyama CLIC4 KEEDKEPLIELFVKAGsDGEsIGNCPFSQRLFMILWLKGVV
Q9Y6E0 S434 Sugiyama STK24 MST3 STK3 ACPGISDTMVAQLVQRLQRYsLSGGGtSsH___________
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Chromatin modifying enzymes R-HSA-3247509 2.473321e-07 6.607 0 0
Cell Cycle R-HSA-1640170 5.502664e-07 6.259 0 0
Chromatin organization R-HSA-4839726 7.184070e-07 6.144 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 9.084057e-07 6.042 0 0
NRAGE signals death through JNK R-HSA-193648 1.741035e-06 5.759 0 0
G alpha (12/13) signalling events R-HSA-416482 2.826211e-06 5.549 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.446855e-05 4.611 0 0
Cell Cycle Checkpoints R-HSA-69620 5.354599e-05 4.271 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 6.125074e-05 4.213 0 0
HDMs demethylate histones R-HSA-3214842 6.579131e-05 4.182 0 0
mRNA 3'-end processing R-HSA-72187 7.059009e-05 4.151 0 0
Cell Cycle, Mitotic R-HSA-69278 7.652351e-05 4.116 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.203690e-04 3.919 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.483695e-04 3.829 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.750428e-04 3.757 0 0
Apoptotic execution phase R-HSA-75153 1.768750e-04 3.752 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.773269e-04 3.751 0 0
Axon guidance R-HSA-422475 1.963692e-04 3.707 0 0
Signal Transduction R-HSA-162582 3.415908e-04 3.466 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.456479e-04 3.461 0 0
Nervous system development R-HSA-9675108 4.397695e-04 3.357 0 0
Oncogenic MAPK signaling R-HSA-6802957 4.637781e-04 3.334 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 4.988401e-04 3.302 0 0
Gene expression (Transcription) R-HSA-74160 5.681559e-04 3.246 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 6.813101e-04 3.167 0 0
RNA Polymerase II Transcription R-HSA-73857 8.343040e-04 3.079 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.119705e-03 2.951 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.217574e-03 2.915 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.217574e-03 2.915 0 0
Regulation of TP53 Activity R-HSA-5633007 1.238275e-03 2.907 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.292913e-03 2.888 0 0
Cellular Senescence R-HSA-2559583 1.315392e-03 2.881 0 0
Death Receptor Signaling R-HSA-73887 1.322526e-03 2.879 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.457319e-03 2.836 0 0
Mitotic Spindle Checkpoint R-HSA-69618 2.105868e-03 2.677 0 0
Kinesins R-HSA-983189 2.141392e-03 2.669 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 2.250847e-03 2.648 0 0
Epigenetic regulation of gene expression R-HSA-212165 2.469167e-03 2.607 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 2.583019e-03 2.588 0 0
Signaling by ROBO receptors R-HSA-376176 2.748479e-03 2.561 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 2.864670e-03 2.543 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 3.705270e-03 2.431 0 0
HATs acetylate histones R-HSA-3214847 3.829938e-03 2.417 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 4.313185e-03 2.365 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 4.911385e-03 2.309 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 5.229184e-03 2.282 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 6.111265e-03 2.214 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.206623e-03 2.207 0 0
Rap1 signalling R-HSA-392517 6.259835e-03 2.203 0 0
RAF activation R-HSA-5673000 7.383638e-03 2.132 0 0
Signaling by AXIN mutants R-HSA-4839735 7.398816e-03 2.131 0 0
Signaling by GSK3beta mutants R-HSA-5339716 7.398816e-03 2.131 0 0
M Phase R-HSA-68886 8.360434e-03 2.078 0 0
Signaling downstream of RAS mutants R-HSA-9649948 8.971186e-03 2.047 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 8.971186e-03 2.047 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 8.971186e-03 2.047 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 8.728116e-03 2.059 0 0
Signaling by RAS mutants R-HSA-6802949 8.971186e-03 2.047 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 9.940008e-03 2.003 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 9.940008e-03 2.003 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 9.940008e-03 2.003 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 9.940008e-03 2.003 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 9.940008e-03 2.003 0 0
MITF-M-dependent gene expression R-HSA-9856651 9.611099e-03 2.017 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.020859e-02 1.991 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.038277e-02 1.984 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.095768e-02 1.960 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.132398e-02 1.946 0 0
Generic Transcription Pathway R-HSA-212436 1.169865e-02 1.932 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.207859e-02 1.918 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.304726e-02 1.884 0 0
GLI proteins bind promoters of Hh responsive genes to promote transcription R-HSA-5635851 1.305424e-02 1.884 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.319563e-02 1.880 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.451312e-02 1.838 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.399878e-02 1.854 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.522284e-02 1.818 0 0
Polo-like kinase mediated events R-HSA-156711 1.601264e-02 1.796 0 0
Mitotic Prometaphase R-HSA-68877 1.637327e-02 1.786 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.627158e-02 1.789 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.654652e-02 1.781 0 0
G2/M Transition R-HSA-69275 1.675292e-02 1.776 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.677755e-02 1.775 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.856077e-02 1.731 0 0
Mitotic Anaphase R-HSA-68882 1.813249e-02 1.742 0 0
Diseases of Telomere Maintenance R-HSA-9673013 2.146235e-02 1.668 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 2.146235e-02 1.668 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 2.146235e-02 1.668 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 2.146235e-02 1.668 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 2.146235e-02 1.668 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 2.118328e-02 1.674 0 0
Germ layer formation at gastrulation R-HSA-9754189 1.965420e-02 1.707 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 2.113609e-02 1.675 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.041739e-02 1.690 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.075555e-02 1.683 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.895446e-02 1.722 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.919597e-02 1.717 0 0
MAPK family signaling cascades R-HSA-5683057 1.936384e-02 1.713 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.996697e-02 1.700 0 0
mRNA Splicing R-HSA-72172 2.148157e-02 1.668 0 0
ChREBP activates metabolic gene expression R-HSA-163765 2.156286e-02 1.666 0 0
Signaling by APC mutants R-HSA-4839744 2.156286e-02 1.666 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 2.156286e-02 1.666 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 2.156286e-02 1.666 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 2.156286e-02 1.666 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.383750e-02 1.623 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.383750e-02 1.623 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.313909e-02 1.636 0 0
Negative regulation of MAPK pathway R-HSA-5675221 2.407776e-02 1.618 0 0
G2/M DNA damage checkpoint R-HSA-69473 2.468679e-02 1.608 0 0
RET signaling R-HSA-8853659 2.484335e-02 1.605 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 2.684371e-02 1.571 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 2.684371e-02 1.571 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 2.500899e-02 1.602 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 2.500899e-02 1.602 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.500899e-02 1.602 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.631131e-02 1.580 0 0
Activation of RAC1 R-HSA-428540 2.786192e-02 1.555 0 0
Signaling by AMER1 mutants R-HSA-4839748 2.786192e-02 1.555 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 2.840515e-02 1.547 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.851378e-02 1.545 0 0
Diseases of mitotic cell cycle R-HSA-9675126 2.916689e-02 1.535 0 0
Signaling by WNT in cancer R-HSA-4791275 2.916689e-02 1.535 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 3.047253e-02 1.516 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 3.047253e-02 1.516 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 3.198805e-02 1.495 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 3.217724e-02 1.492 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 3.274583e-02 1.485 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.395688e-02 1.469 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 3.418740e-02 1.466 0 0
RMTs methylate histone arginines R-HSA-3214858 3.464555e-02 1.460 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 3.521935e-02 1.453 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 3.521935e-02 1.453 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.525777e-02 1.453 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 3.609051e-02 1.443 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 3.609051e-02 1.443 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 3.609051e-02 1.443 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 3.953600e-02 1.403 0 0
Separation of Sister Chromatids R-HSA-2467813 3.919958e-02 1.407 0 0
Estrogen-dependent gene expression R-HSA-9018519 4.135734e-02 1.383 0 0
AURKA Activation by TPX2 R-HSA-8854518 4.191702e-02 1.378 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 4.216839e-02 1.375 0 0
Intracellular signaling by second messengers R-HSA-9006925 4.237752e-02 1.373 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 4.351296e-02 1.361 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 4.367099e-02 1.360 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 4.367099e-02 1.360 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 4.465421e-02 1.350 0 0
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316 4.491204e-02 1.348 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 4.695703e-02 1.328 0 0
DNA Double Strand Break Response R-HSA-5693606 4.586636e-02 1.339 0 0
DNA Double-Strand Break Repair R-HSA-5693532 4.941920e-02 1.306 0 0
Cardiac conduction R-HSA-5576891 4.519464e-02 1.345 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 4.546421e-02 1.342 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 4.658751e-02 1.332 0 0
TCF dependent signaling in response to WNT R-HSA-201681 5.087150e-02 1.294 0 0
MAP2K and MAPK activation R-HSA-5674135 5.171280e-02 1.286 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 5.226158e-02 1.282 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 5.323787e-02 1.274 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 5.330526e-02 1.273 0 0
Apoptosis R-HSA-109581 5.341933e-02 1.272 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.456610e-02 1.263 0 0
Signaling by MAPK mutants R-HSA-9652817 6.154297e-02 1.211 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.786701e-02 1.238 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 5.944004e-02 1.226 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 6.288000e-02 1.201 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 6.195612e-02 1.208 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 5.955098e-02 1.225 0 0
Protein-protein interactions at synapses R-HSA-6794362 6.234986e-02 1.205 0 0
MTOR signalling R-HSA-165159 5.755816e-02 1.240 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 5.944004e-02 1.226 0 0
Interleukin-7 signaling R-HSA-1266695 6.187744e-02 1.208 0 0
DCC mediated attractive signaling R-HSA-418885 6.392654e-02 1.194 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 6.425326e-02 1.192 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 6.906173e-02 1.161 0 0
Diseases of cellular response to stress R-HSA-9675132 7.431118e-02 1.129 0 0
Diseases of Cellular Senescence R-HSA-9630747 7.431118e-02 1.129 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 7.431118e-02 1.129 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 7.665582e-02 1.115 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 7.507010e-02 1.125 0 0
Processing of DNA double-strand break ends R-HSA-5693607 7.910902e-02 1.102 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 7.788390e-02 1.109 0 0
Netrin-1 signaling R-HSA-373752 7.050255e-02 1.152 0 0
Homology Directed Repair R-HSA-5693538 7.106708e-02 1.148 0 0
TRP channels R-HSA-3295583 7.054540e-02 1.152 0 0
Neurexins and neuroligins R-HSA-6794361 7.771952e-02 1.109 0 0
Cardiogenesis R-HSA-9733709 7.448661e-02 1.128 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 7.448661e-02 1.128 0 0
Post NMDA receptor activation events R-HSA-438064 7.719321e-02 1.112 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 7.665582e-02 1.115 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 7.761171e-02 1.110 0 0
Programmed Cell Death R-HSA-5357801 7.277812e-02 1.138 0 0
Drug resistance of KIT mutants R-HSA-9669937 1.055403e-01 0.977 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.055403e-01 0.977 0 0
KIT mutants bind TKIs R-HSA-9669921 1.055403e-01 0.977 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.055403e-01 0.977 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 1.055403e-01 0.977 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.055403e-01 0.977 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.055403e-01 0.977 0 0
Imatinib-resistant KIT mutants R-HSA-9669917 1.055403e-01 0.977 0 0
Sorafenib-resistant KIT mutants R-HSA-9669936 1.055403e-01 0.977 0 0
Dasatinib-resistant KIT mutants R-HSA-9669914 1.055403e-01 0.977 0 0
Deletions in the AXIN1 gene destabilize the destruction complex R-HSA-5467345 1.055403e-01 0.977 0 0
Nilotinib-resistant KIT mutants R-HSA-9669926 1.055403e-01 0.977 0 0
Sunitinib-resistant KIT mutants R-HSA-9669934 1.055403e-01 0.977 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.055403e-01 0.977 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.055403e-01 0.977 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 1.055403e-01 0.977 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.055403e-01 0.977 0 0
Masitinib-resistant KIT mutants R-HSA-9669924 1.055403e-01 0.977 0 0
Regorafenib-resistant KIT mutants R-HSA-9669929 1.055403e-01 0.977 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.999475e-01 0.699 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.999475e-01 0.699 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.999475e-01 0.699 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 1.999475e-01 0.699 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.999475e-01 0.699 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 1.999475e-01 0.699 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 1.999475e-01 0.699 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.081441e-01 0.966 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.451486e-01 0.838 0 0
PI and PC transport between ER and Golgi membranes R-HSA-1483196 2.843952e-01 0.546 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 2.843952e-01 0.546 0 0
Signaling by extracellular domain mutants of KIT R-HSA-9680187 2.843952e-01 0.546 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 2.843952e-01 0.546 0 0
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935 2.843952e-01 0.546 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.843952e-01 0.546 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.843952e-01 0.546 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 2.843952e-01 0.546 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 2.843952e-01 0.546 0 0
MyD88 deficiency (TLR5) R-HSA-5602680 2.843952e-01 0.546 0 0
Intestinal infectious diseases R-HSA-8942233 2.843952e-01 0.546 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.843952e-01 0.546 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5660686 2.843952e-01 0.546 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.843952e-01 0.546 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5619101 2.843952e-01 0.546 0 0
Signaling by kinase domain mutants of KIT R-HSA-9669933 2.843952e-01 0.546 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 1.026322e-01 0.989 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.026322e-01 0.989 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.026322e-01 0.989 0 0
SOS-mediated signalling R-HSA-112412 1.026322e-01 0.989 0 0
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974 1.026322e-01 0.989 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 1.842792e-01 0.735 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 1.842792e-01 0.735 0 0
IRS activation R-HSA-74713 1.842792e-01 0.735 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.842792e-01 0.735 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 1.263292e-01 0.898 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 1.517584e-01 0.819 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 2.246755e-01 0.648 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.246755e-01 0.648 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 2.246755e-01 0.648 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 3.599337e-01 0.444 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 3.599337e-01 0.444 0 0
Interaction between PHLDA1 and AURKA R-HSA-8854521 3.599337e-01 0.444 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 3.599337e-01 0.444 0 0
Defective DHDDS causes RP59 R-HSA-4755609 3.599337e-01 0.444 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 3.599337e-01 0.444 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 3.599337e-01 0.444 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 3.599337e-01 0.444 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 3.599337e-01 0.444 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 3.599337e-01 0.444 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 3.599337e-01 0.444 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 3.599337e-01 0.444 0 0
Potassium transport channels R-HSA-1296067 3.599337e-01 0.444 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 3.599337e-01 0.444 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 3.599337e-01 0.444 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 3.599337e-01 0.444 0 0
HHAT G278V doesn't palmitoylate Hh-Np R-HSA-5658034 3.599337e-01 0.444 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 3.599337e-01 0.444 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 3.599337e-01 0.444 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) R-HSA-5655799 3.599337e-01 0.444 0 0
Processing of SMDT1 R-HSA-8949664 1.245227e-01 0.905 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.245227e-01 0.905 0 0
PI3K/AKT activation R-HSA-198203 1.786353e-01 0.748 0 0
Regulation of KIT signaling R-HSA-1433559 1.441457e-01 0.841 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 2.656351e-01 0.576 0 0
Ephrin signaling R-HSA-3928664 1.175641e-01 0.930 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 2.066796e-01 0.685 0 0
DNA methylation R-HSA-5334118 1.006493e-01 0.997 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.503605e-01 0.823 0 0
Differentiation of T cells R-HSA-9945266 1.866106e-01 0.729 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 1.866106e-01 0.729 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.866106e-01 0.729 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 2.356217e-01 0.628 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 2.356217e-01 0.628 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 2.356217e-01 0.628 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 2.356217e-01 0.628 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 3.065893e-01 0.513 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 3.065893e-01 0.513 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 3.065893e-01 0.513 0 0
Netrin mediated repulsion signals R-HSA-418886 3.065893e-01 0.513 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 3.065893e-01 0.513 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 3.065893e-01 0.513 0 0
Axonal growth stimulation R-HSA-209563 4.275024e-01 0.369 0 0
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336 4.275024e-01 0.369 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 4.275024e-01 0.369 0 0
Invadopodia formation R-HSA-8941237 4.275024e-01 0.369 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 4.275024e-01 0.369 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 4.275024e-01 0.369 0 0
Tight junction interactions R-HSA-420029 1.366269e-01 0.864 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 8.474063e-02 1.072 0 0
Phase 2 - plateau phase R-HSA-5576893 2.091923e-01 0.679 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.331602e-02 1.030 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 2.652065e-01 0.576 0 0
Polymerase switching R-HSA-69091 2.652065e-01 0.576 0 0
Leading Strand Synthesis R-HSA-69109 2.652065e-01 0.576 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.126569e-01 0.948 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.865099e-01 0.729 0 0
Type I hemidesmosome assembly R-HSA-446107 3.470834e-01 0.460 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 3.470834e-01 0.460 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 3.470834e-01 0.460 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 3.470834e-01 0.460 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 8.476392e-02 1.072 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 8.382472e-02 1.077 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 2.951970e-01 0.530 0 0
HDACs deacetylate histones R-HSA-3214815 9.999526e-02 1.000 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 2.563883e-01 0.591 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.254209e-01 0.647 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 1.998115e-01 0.699 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.056731e-01 0.976 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.056731e-01 0.976 0 0
Centrosome maturation R-HSA-380287 8.700677e-02 1.060 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.392888e-01 0.856 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 2.170692e-01 0.663 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 2.170692e-01 0.663 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.807397e-01 0.552 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 2.807397e-01 0.552 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 4.879417e-01 0.312 0 0
TNFR1-mediated ceramide production R-HSA-5626978 4.879417e-01 0.312 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 4.879417e-01 0.312 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 4.879417e-01 0.312 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 4.879417e-01 0.312 0 0
MPS VI - Maroteaux-Lamy syndrome R-HSA-2206285 4.879417e-01 0.312 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 4.879417e-01 0.312 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 4.879417e-01 0.312 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 1.000774e-01 1.000 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 1.497470e-01 0.825 0 0
Co-inhibition by CTLA4 R-HSA-389513 3.054241e-01 0.515 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 3.054241e-01 0.515 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 3.054241e-01 0.515 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 3.054241e-01 0.515 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 3.054241e-01 0.515 0 0
Erythropoietin activates RAS R-HSA-9027284 3.555446e-01 0.449 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 3.555446e-01 0.449 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 3.555446e-01 0.449 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 3.555446e-01 0.449 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 3.555446e-01 0.449 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 2.875670e-01 0.541 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 2.875670e-01 0.541 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 4.253361e-01 0.371 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 3.089665e-01 0.510 0 0
Phosphorylation of the APC/C R-HSA-176412 3.855286e-01 0.414 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 3.855286e-01 0.414 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 2.738206e-01 0.563 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 2.738206e-01 0.563 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 3.553163e-01 0.449 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 3.305763e-01 0.481 0 0
Formation of the Early Elongation Complex R-HSA-113418 3.305763e-01 0.481 0 0
Translation initiation complex formation R-HSA-72649 2.596241e-01 0.586 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 3.083567e-01 0.511 0 0
Late endosomal microautophagy R-HSA-9615710 3.523205e-01 0.453 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.803033e-01 0.420 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 4.151715e-01 0.382 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 4.151715e-01 0.382 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.626063e-01 0.335 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 4.626063e-01 0.335 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 5.420035e-01 0.266 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 5.420035e-01 0.266 0 0
Defective SLC1A3 causes episodic ataxia 6 (EA6) R-HSA-5619062 5.420035e-01 0.266 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 5.420035e-01 0.266 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 5.420035e-01 0.266 0 0
Defective F9 activation R-HSA-9673221 5.420035e-01 0.266 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 2.888482e-01 0.539 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 3.482252e-01 0.458 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 3.188778e-01 0.496 0 0
Voltage gated Potassium channels R-HSA-1296072 3.677749e-01 0.434 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 4.443378e-01 0.352 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.912424e-01 0.536 0 0
ERKs are inactivated R-HSA-202670 4.984151e-01 0.302 0 0
Regulation of PTEN gene transcription R-HSA-8943724 3.495015e-01 0.457 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 3.719717e-01 0.429 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 4.069528e-01 0.390 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 3.973539e-01 0.401 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 4.542632e-01 0.343 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 3.403316e-01 0.468 0 0
Nuclear Receptor transcription pathway R-HSA-383280 3.658929e-01 0.437 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 4.264841e-01 0.370 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 4.606410e-01 0.337 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 5.326559e-01 0.274 0 0
PDE3B signalling R-HSA-165160 5.903605e-01 0.229 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 5.903605e-01 0.229 0 0
Cam-PDE 1 activation R-HSA-111957 5.903605e-01 0.229 0 0
PKB-mediated events R-HSA-109703 5.903605e-01 0.229 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 5.903605e-01 0.229 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 5.903605e-01 0.229 0 0
Defective CSF2RA causes SMDP4 R-HSA-5688890 5.903605e-01 0.229 0 0
Phase 1 - inactivation of fast Na+ channels R-HSA-5576894 5.903605e-01 0.229 0 0
Signaling by RNF43 mutants R-HSA-5340588 5.903605e-01 0.229 0 0
Defective CSF2RB causes SMDP5 R-HSA-5688849 5.903605e-01 0.229 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 5.019273e-01 0.299 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 5.019273e-01 0.299 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 5.019273e-01 0.299 0 0
Packaging Of Telomere Ends R-HSA-171306 5.019273e-01 0.299 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 4.114779e-01 0.386 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 4.114779e-01 0.386 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.686996e-01 0.329 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 4.843155e-01 0.315 0 0
Telomere Extension By Telomerase R-HSA-171319 5.250668e-01 0.280 0 0
HIV elongation arrest and recovery R-HSA-167287 5.250668e-01 0.280 0 0
Pausing and recovery of HIV elongation R-HSA-167290 5.250668e-01 0.280 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 4.891505e-01 0.311 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 4.692332e-01 0.329 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 5.036528e-01 0.298 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 5.541662e-01 0.256 0 0
Formation of a pool of free 40S subunits R-HSA-72689 5.182623e-01 0.285 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 5.401978e-01 0.267 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 5.401978e-01 0.267 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 5.401978e-01 0.267 0 0
Nucleosome assembly R-HSA-774815 5.401978e-01 0.267 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 5.697057e-01 0.244 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 5.961929e-01 0.225 0 0
Removal of the Flap Intermediate R-HSA-69166 5.961929e-01 0.225 0 0
Erythropoietin activates STAT5 R-HSA-9027283 6.336143e-01 0.198 0 0
STAT5 Activation R-HSA-9645135 6.336143e-01 0.198 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 5.586903e-01 0.253 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 5.759420e-01 0.240 0 0
Trafficking of AMPA receptors R-HSA-399719 5.911250e-01 0.228 0 0
Signaling by KIT in disease R-HSA-9669938 6.039827e-01 0.219 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 6.039827e-01 0.219 0 0
FGFR2 alternative splicing R-HSA-6803529 6.039827e-01 0.219 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.039827e-01 0.219 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 6.232890e-01 0.205 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 6.119021e-01 0.213 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 6.254425e-01 0.204 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 6.254425e-01 0.204 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 6.254425e-01 0.204 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 6.254425e-01 0.204 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 6.223608e-01 0.206 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 6.402712e-01 0.194 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 6.320131e-01 0.199 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 6.320131e-01 0.199 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 6.373644e-01 0.196 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 6.373644e-01 0.196 0 0
Transcription of the HIV genome R-HSA-167172 6.118006e-01 0.213 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 3.045949e-01 0.516 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 3.045949e-01 0.516 0 0
RNA Polymerase III Transcription R-HSA-74158 3.482252e-01 0.458 0 0
Integrin signaling R-HSA-354192 1.499511e-01 0.824 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 6.373644e-01 0.196 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 3.045949e-01 0.516 0 0
EPH-Ephrin signaling R-HSA-2682334 1.133543e-01 0.946 0 0
DAP12 signaling R-HSA-2424491 2.170692e-01 0.663 0 0
Regulation of endogenous retroelements R-HSA-9842860 8.830360e-02 1.054 0 0
Hedgehog 'off' state R-HSA-5610787 1.836564e-01 0.736 0 0
Downstream signal transduction R-HSA-186763 3.959251e-01 0.402 0 0
HIV Transcription Elongation R-HSA-167169 4.264841e-01 0.370 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 1.175641e-01 0.930 0 0
Signaling by SCF-KIT R-HSA-1433557 2.140437e-01 0.669 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 3.741266e-01 0.427 0 0
Chromosome Maintenance R-HSA-73886 3.409597e-01 0.467 0 0
Signaling by PDGFR in disease R-HSA-9671555 3.553163e-01 0.449 0 0
Telomere Maintenance R-HSA-157579 4.292506e-01 0.367 0 0
Lagging Strand Synthesis R-HSA-69186 5.541662e-01 0.256 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.175641e-01 0.930 0 0
Oncogene Induced Senescence R-HSA-2559585 1.022685e-01 0.990 0 0
Extension of Telomeres R-HSA-180786 6.185173e-01 0.209 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.517584e-01 0.819 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 2.091923e-01 0.679 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 2.436436e-01 0.613 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 2.220174e-01 0.654 0 0
Activation of the pre-replicative complex R-HSA-68962 5.697057e-01 0.244 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.324393e-01 0.878 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 4.264841e-01 0.370 0 0
HSF1-dependent transactivation R-HSA-3371571 4.862619e-01 0.313 0 0
FOXO-mediated transcription R-HSA-9614085 3.468302e-01 0.460 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.683423e-01 0.774 0 0
Aggrephagy R-HSA-9646399 6.011991e-01 0.221 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.103774e-01 0.957 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.400107e-01 0.854 0 0
Processive synthesis on the lagging strand R-HSA-69183 6.254425e-01 0.204 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 5.747018e-01 0.241 0 0
Signaling by ERBB2 R-HSA-1227986 4.878356e-01 0.312 0 0
Frs2-mediated activation R-HSA-170968 1.245227e-01 0.905 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 5.311835e-01 0.275 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.175641e-01 0.930 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 1.499511e-01 0.824 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 3.188778e-01 0.496 0 0
ESR-mediated signaling R-HSA-8939211 2.892035e-01 0.539 0 0
Cyclin D associated events in G1 R-HSA-69231 2.286718e-01 0.641 0 0
G1 Phase R-HSA-69236 2.286718e-01 0.641 0 0
Signaling by Nuclear Receptors R-HSA-9006931 4.421575e-01 0.354 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 1.842792e-01 0.735 0 0
Formation of lateral plate mesoderm R-HSA-9758920 2.246755e-01 0.648 0 0
Mitochondrial calcium ion transport R-HSA-8949215 8.489849e-02 1.071 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.065893e-01 0.513 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 2.324958e-01 0.634 0 0
DNA strand elongation R-HSA-69190 2.529726e-01 0.597 0 0
Regulation of CDH11 function R-HSA-9762292 4.253361e-01 0.371 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.903558e-01 0.537 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 3.803033e-01 0.420 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 4.443378e-01 0.352 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 4.069528e-01 0.390 0 0
Peptide chain elongation R-HSA-156902 5.185870e-01 0.285 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.070918e-01 0.970 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.890500e-01 0.723 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 1.781510e-01 0.749 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 1.781510e-01 0.749 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 2.483428e-01 0.605 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 5.326559e-01 0.274 0 0
Formation of definitive endoderm R-HSA-9823730 3.054241e-01 0.515 0 0
Resolution of D-Loop Structures R-HSA-5693537 4.606410e-01 0.337 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 2.108700e-01 0.676 0 0
TNF signaling R-HSA-75893 5.709801e-01 0.243 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 1.517584e-01 0.819 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 1.866106e-01 0.729 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 2.652065e-01 0.576 0 0
Adrenoceptors R-HSA-390696 3.470834e-01 0.460 0 0
p75NTR regulates axonogenesis R-HSA-193697 3.867583e-01 0.413 0 0
Regulation of gap junction activity R-HSA-191650 4.879417e-01 0.312 0 0
TGFBR3 expression R-HSA-9839394 2.664560e-01 0.574 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.906783e-01 0.720 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 5.420035e-01 0.266 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 2.586712e-01 0.587 0 0
Synaptic adhesion-like molecules R-HSA-8849932 4.729108e-01 0.325 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 4.392416e-01 0.357 0 0
DARPP-32 events R-HSA-180024 5.476741e-01 0.261 0 0
Telomere C-strand synthesis initiation R-HSA-174430 6.254425e-01 0.204 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 6.254425e-01 0.204 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 2.017099e-01 0.695 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.053520e-01 0.977 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.053520e-01 0.977 0 0
Prolonged ERK activation events R-HSA-169893 1.866106e-01 0.729 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.998266e-01 0.699 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 6.185637e-01 0.209 0 0
S Phase R-HSA-69242 2.365494e-01 0.626 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 4.459161e-01 0.351 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 1.514489e-01 0.820 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 9.804831e-02 1.009 0 0
Cap-dependent Translation Initiation R-HSA-72737 5.880040e-01 0.231 0 0
Receptor Mediated Mitophagy R-HSA-8934903 1.786353e-01 0.748 0 0
Signal attenuation R-HSA-74749 1.786353e-01 0.748 0 0
Long-term potentiation R-HSA-9620244 1.366269e-01 0.864 0 0
Repression of WNT target genes R-HSA-4641265 2.652065e-01 0.576 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.859369e-01 0.731 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 5.326559e-01 0.274 0 0
Eukaryotic Translation Initiation R-HSA-72613 5.880040e-01 0.231 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.259347e-01 0.487 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 2.214958e-01 0.655 0 0
Signaling by WNT R-HSA-195721 1.531410e-01 0.815 0 0
Generation of second messenger molecules R-HSA-202433 6.011991e-01 0.221 0 0
Molecules associated with elastic fibres R-HSA-2129379 5.911250e-01 0.228 0 0
Calmodulin induced events R-HSA-111933 1.126569e-01 0.948 0 0
Nuclear Envelope Breakdown R-HSA-2980766 4.384950e-01 0.358 0 0
GPVI-mediated activation cascade R-HSA-114604 5.231842e-01 0.281 0 0
DAG and IP3 signaling R-HSA-1489509 1.433848e-01 0.843 0 0
Mitotic Prophase R-HSA-68875 1.208225e-01 0.918 0 0
Calcineurin activates NFAT R-HSA-2025928 1.517584e-01 0.819 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 1.441457e-01 0.841 0 0
Ca2+ activated K+ channels R-HSA-1296052 3.065893e-01 0.513 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.120255e-01 0.951 0 0
CaM pathway R-HSA-111997 1.126569e-01 0.948 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 3.470834e-01 0.460 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 3.470834e-01 0.460 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 3.470834e-01 0.460 0 0
Meiotic synapsis R-HSA-1221632 8.476392e-02 1.072 0 0
Nuclear RNA decay R-HSA-9930044 1.499511e-01 0.824 0 0
Activation of ATR in response to replication stress R-HSA-176187 1.499511e-01 0.824 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 3.867583e-01 0.413 0 0
Formation of the posterior neural plate R-HSA-9832991 4.626063e-01 0.335 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 5.420035e-01 0.266 0 0
Defective pyroptosis R-HSA-9710421 3.436637e-01 0.464 0 0
MET promotes cell motility R-HSA-8875878 3.873673e-01 0.412 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 4.542632e-01 0.343 0 0
Eukaryotic Translation Elongation R-HSA-156842 4.656982e-01 0.332 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 5.652605e-01 0.248 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 4.692332e-01 0.329 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 5.541662e-01 0.256 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 6.011991e-01 0.221 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 6.102434e-01 0.214 0 0
Signaling by Hedgehog R-HSA-5358351 4.637662e-01 0.334 0 0
PLC beta mediated events R-HSA-112043 1.546479e-01 0.811 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 3.489262e-01 0.457 0 0
Ion homeostasis R-HSA-5578775 1.081806e-01 0.966 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 1.499511e-01 0.824 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 4.606410e-01 0.337 0 0
RNA Polymerase I Transcription R-HSA-73864 4.902766e-01 0.310 0 0
Interleukin-2 signaling R-HSA-9020558 4.626063e-01 0.335 0 0
Platelet calcium homeostasis R-HSA-418360 3.523205e-01 0.453 0 0
DNA Replication Pre-Initiation R-HSA-69002 5.907737e-01 0.229 0 0
Cilium Assembly R-HSA-5617833 5.539544e-01 0.257 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 6.337066e-01 0.198 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 6.337066e-01 0.198 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 6.337066e-01 0.198 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 6.337066e-01 0.198 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 1.581651e-01 0.801 0 0
Biotin transport and metabolism R-HSA-196780 3.555446e-01 0.449 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 4.023642e-01 0.395 0 0
Signaling by NOTCH1 R-HSA-1980143 4.611750e-01 0.336 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 5.911250e-01 0.228 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 2.246755e-01 0.648 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 2.066796e-01 0.685 0 0
Specification of the neural plate border R-HSA-9834899 1.335091e-01 0.874 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 3.470834e-01 0.460 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 1.350655e-01 0.869 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 4.879417e-01 0.312 0 0
FGFR1 mutant receptor activation R-HSA-1839124 2.715073e-01 0.566 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 5.903605e-01 0.229 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 5.433341e-01 0.265 0 0
p38MAPK events R-HSA-171007 6.254425e-01 0.204 0 0
Eukaryotic Translation Termination R-HSA-72764 6.345290e-01 0.198 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 6.402712e-01 0.194 0 0
Hedgehog 'on' state R-HSA-5632684 1.785517e-01 0.748 0 0
Signalling to ERKs R-HSA-187687 1.930347e-01 0.714 0 0
Ca-dependent events R-HSA-111996 1.997892e-01 0.699 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.914272e-01 0.718 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.914272e-01 0.718 0 0
Mismatch Repair R-HSA-5358508 4.729108e-01 0.325 0 0
DNA Repair R-HSA-73894 3.627419e-01 0.440 0 0
Neurofascin interactions R-HSA-447043 2.656351e-01 0.576 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 2.656351e-01 0.576 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 2.356217e-01 0.628 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 1.930347e-01 0.714 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.783066e-01 0.320 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 6.195368e-01 0.208 0 0
Formation of the ureteric bud R-HSA-9830674 6.274643e-01 0.202 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.355728e-01 0.868 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.355728e-01 0.868 0 0
Meiosis R-HSA-1500620 1.036777e-01 0.984 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.150487e-01 0.502 0 0
Autophagy R-HSA-9612973 3.880610e-01 0.411 0 0
Ub-specific processing proteases R-HSA-5689880 3.938167e-01 0.405 0 0
Developmental Biology R-HSA-1266738 5.536221e-01 0.257 0 0
Metabolism of RNA R-HSA-8953854 5.345124e-01 0.272 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 3.555446e-01 0.449 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 4.298637e-01 0.367 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 4.707396e-01 0.327 0 0
G2/M Checkpoints R-HSA-69481 8.155637e-02 1.089 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 4.298637e-01 0.367 0 0
Integration of energy metabolism R-HSA-163685 2.681780e-01 0.572 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 1.725140e-01 0.763 0 0
Semaphorin interactions R-HSA-373755 1.056731e-01 0.976 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.202764e-01 0.657 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.083942e-01 0.681 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 4.606779e-01 0.337 0 0
Assembly of the pre-replicative complex R-HSA-68867 4.789456e-01 0.320 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.937204e-01 0.532 0 0
G0 and Early G1 R-HSA-1538133 2.529726e-01 0.597 0 0
Ca2+ pathway R-HSA-4086398 5.491731e-01 0.260 0 0
G-protein mediated events R-HSA-112040 2.214958e-01 0.655 0 0
Muscle contraction R-HSA-397014 1.782739e-01 0.749 0 0
Interleukin-1 signaling R-HSA-9020702 5.938910e-01 0.226 0 0
Inhibition of PKR R-HSA-169131 1.999475e-01 0.699 0 0
MTF1 activates gene expression R-HSA-5660489 1.451486e-01 0.838 0 0
Inhibition of Host mRNA Processing and RNA Silencing R-HSA-168315 2.843952e-01 0.546 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.843952e-01 0.546 0 0
Unwinding of DNA R-HSA-176974 1.517584e-01 0.819 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 2.246755e-01 0.648 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 3.599337e-01 0.444 0 0
Interleukin-33 signaling R-HSA-9014843 3.599337e-01 0.444 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.245227e-01 0.905 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 9.663384e-02 1.015 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 4.275024e-01 0.369 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 4.275024e-01 0.369 0 0
MET interacts with TNS proteins R-HSA-8875513 4.275024e-01 0.369 0 0
Signaling by LTK R-HSA-9842663 2.652065e-01 0.576 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.865099e-01 0.729 0 0
mTORC1-mediated signalling R-HSA-166208 2.056594e-01 0.687 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 1.781510e-01 0.749 0 0
ARMS-mediated activation R-HSA-170984 3.867583e-01 0.413 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 4.879417e-01 0.312 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 4.879417e-01 0.312 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.241922e-01 0.649 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 4.253361e-01 0.371 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 4.253361e-01 0.371 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 3.089665e-01 0.510 0 0
Phase 4 - resting membrane potential R-HSA-5576886 3.855286e-01 0.414 0 0
Disorders of Developmental Biology R-HSA-9675151 4.151715e-01 0.382 0 0
Trafficking of myristoylated proteins to the cilium R-HSA-5624138 5.420035e-01 0.266 0 0
Suppression of autophagy R-HSA-9636569 5.420035e-01 0.266 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 5.420035e-01 0.266 0 0
Meiotic recombination R-HSA-912446 3.389186e-01 0.470 0 0
EGFR downregulation R-HSA-182971 3.959251e-01 0.402 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.072318e-01 0.513 0 0
Sodium/Calcium exchangers R-HSA-425561 4.984151e-01 0.302 0 0
Formation of the Editosome R-HSA-75094 5.903605e-01 0.229 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 5.903605e-01 0.229 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 5.903605e-01 0.229 0 0
Phosphorylation of Emi1 R-HSA-176417 5.903605e-01 0.229 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 4.611750e-01 0.336 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 4.921308e-01 0.308 0 0
Signalling to RAS R-HSA-167044 5.541662e-01 0.256 0 0
cGMP effects R-HSA-418457 5.961929e-01 0.225 0 0
Signaling by VEGF R-HSA-194138 5.964718e-01 0.224 0 0
Notch-HLH transcription pathway R-HSA-350054 6.039827e-01 0.219 0 0
Degradation of CDH1 R-HSA-9766229 6.102434e-01 0.214 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 6.254425e-01 0.204 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 5.027835e-01 0.299 0 0
Cell junction organization R-HSA-446728 1.770658e-01 0.752 0 0
DAP12 interactions R-HSA-2172127 5.218440e-01 0.282 0 0
Macroautophagy R-HSA-1632852 4.022530e-01 0.396 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 4.774597e-01 0.321 0 0
G1/S Transition R-HSA-69206 4.948690e-01 0.306 0 0
Signaling by FGFR in disease R-HSA-1226099 4.318199e-01 0.365 0 0
Opioid Signalling R-HSA-111885 5.179939e-01 0.286 0 0
Cell-cell junction organization R-HSA-421270 3.293926e-01 0.482 0 0
Neuronal System R-HSA-112316 6.027249e-01 0.220 0 0
Adherens junctions interactions R-HSA-418990 4.908046e-01 0.309 0 0
Signaling by FGFR4 in disease R-HSA-5655291 5.961929e-01 0.225 0 0
Stabilization of p53 R-HSA-69541 5.823703e-01 0.235 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.553163e-01 0.449 0 0
FLT3 signaling in disease R-HSA-9682385 3.482252e-01 0.458 0 0
NGF-stimulated transcription R-HSA-9031628 2.903084e-01 0.537 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 6.465283e-01 0.189 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 2.569461e-01 0.590 0 0
Rab regulation of trafficking R-HSA-9007101 3.919365e-01 0.407 0 0
Deubiquitination R-HSA-5688426 2.380570e-01 0.623 0 0
Membrane Trafficking R-HSA-199991 4.051496e-01 0.392 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.609244e-01 0.793 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 6.320131e-01 0.199 0 0
Cell-Cell communication R-HSA-1500931 2.484640e-01 0.605 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 4.264841e-01 0.370 0 0
Interleukin-2 family signaling R-HSA-451927 2.738206e-01 0.563 0 0
Signaling by Hippo R-HSA-2028269 2.324958e-01 0.634 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.832655e-01 0.737 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.648844e-01 0.783 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.865099e-01 0.729 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 3.470834e-01 0.460 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 3.867583e-01 0.413 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 2.336452e-01 0.631 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 4.151715e-01 0.382 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 4.151715e-01 0.382 0 0
TBC/RABGAPs R-HSA-8854214 5.032061e-01 0.298 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 5.566781e-01 0.254 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 5.566781e-01 0.254 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 5.566781e-01 0.254 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 5.311835e-01 0.275 0 0
FLT3 Signaling R-HSA-9607240 9.331602e-02 1.030 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.563883e-01 0.591 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.001556e-01 0.699 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 4.023642e-01 0.395 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.715141e-01 0.566 0 0
Signaling by ERBB4 R-HSA-1236394 4.318199e-01 0.365 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 2.246755e-01 0.648 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.648844e-01 0.783 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 2.951970e-01 0.530 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 3.867583e-01 0.413 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 3.867583e-01 0.413 0 0
Signaling by EGFR R-HSA-177929 1.833835e-01 0.737 0 0
Carnitine shuttle R-HSA-200425 4.051828e-01 0.392 0 0
Heme signaling R-HSA-9707616 3.805084e-01 0.420 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 5.326559e-01 0.274 0 0
Pervasive developmental disorders R-HSA-9005895 5.326559e-01 0.274 0 0
Disorders of Nervous System Development R-HSA-9697154 5.326559e-01 0.274 0 0
Release of Hh-Np from the secreting cell R-HSA-5362798 5.903605e-01 0.229 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 5.903605e-01 0.229 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 5.961929e-01 0.225 0 0
G-protein beta:gamma signalling R-HSA-397795 6.320131e-01 0.199 0 0
Interleukin-1 family signaling R-HSA-446652 4.357680e-01 0.361 0 0
Sensory processing of sound R-HSA-9659379 2.696397e-01 0.569 0 0
Signaling by NTRKs R-HSA-166520 1.741863e-01 0.759 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.089633e-01 0.963 0 0
Diseases of programmed cell death R-HSA-9645723 2.016061e-01 0.695 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 3.867583e-01 0.413 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 5.652605e-01 0.248 0 0
Selective autophagy R-HSA-9663891 6.400992e-01 0.194 0 0
Formation of the nephric duct R-HSA-9830364 1.366269e-01 0.864 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 6.373644e-01 0.196 0 0
Uptake and function of anthrax toxins R-HSA-5210891 4.443378e-01 0.352 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.881977e-01 0.230 0 0
Potassium Channels R-HSA-1296071 6.464892e-01 0.189 0 0
PI Metabolism R-HSA-1483255 2.017099e-01 0.695 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.089665e-01 0.510 0 0
Regulation of insulin secretion R-HSA-422356 5.566781e-01 0.254 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 3.729700e-01 0.428 0 0
Breakdown of the nuclear lamina R-HSA-352238 2.843952e-01 0.546 0 0
DSCAM interactions R-HSA-376172 3.599337e-01 0.444 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.866106e-01 0.729 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 4.275024e-01 0.369 0 0
Alpha-defensins R-HSA-1462054 3.470834e-01 0.460 0 0
Sensory perception of sour taste R-HSA-9729555 4.879417e-01 0.312 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 3.303209e-01 0.481 0 0
Signaling by ALK R-HSA-201556 2.569461e-01 0.590 0 0
Negative regulation of FLT3 R-HSA-9706369 3.855286e-01 0.414 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.094618e-01 0.509 0 0
Synthesis of PI R-HSA-1483226 4.626063e-01 0.335 0 0
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403 5.420035e-01 0.266 0 0
Interleukin-36 pathway R-HSA-9014826 5.420035e-01 0.266 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 5.420035e-01 0.266 0 0
PTK6 Down-Regulation R-HSA-8849472 5.420035e-01 0.266 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 3.973539e-01 0.401 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 4.392416e-01 0.357 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 5.903605e-01 0.229 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 4.843155e-01 0.315 0 0
Creatine metabolism R-HSA-71288 5.278992e-01 0.277 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 5.378122e-01 0.269 0 0
Abacavir transmembrane transport R-HSA-2161517 6.336143e-01 0.198 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 6.195368e-01 0.208 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 6.337066e-01 0.198 0 0
Co-stimulation by CD28 R-HSA-389356 4.331807e-01 0.363 0 0
Activation of BH3-only proteins R-HSA-114452 5.697057e-01 0.244 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 5.795406e-01 0.237 0 0
L1CAM interactions R-HSA-373760 3.805445e-01 0.420 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 2.875670e-01 0.541 0 0
MHC class II antigen presentation R-HSA-2132295 5.632769e-01 0.249 0 0
Signaling by TGFBR3 R-HSA-9839373 5.582391e-01 0.253 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.517584e-01 0.819 0 0
Protein hydroxylation R-HSA-9629569 5.278992e-01 0.277 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 5.652605e-01 0.248 0 0
Kidney development R-HSA-9830369 5.971357e-01 0.224 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 2.325398e-01 0.634 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.669512e-01 0.777 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 5.046874e-01 0.297 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 6.426450e-01 0.192 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 2.656351e-01 0.576 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.499511e-01 0.824 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 2.715073e-01 0.566 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 4.253361e-01 0.371 0 0
PECAM1 interactions R-HSA-210990 4.626063e-01 0.335 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 6.336143e-01 0.198 0 0
Stimuli-sensing channels R-HSA-2672351 2.707352e-01 0.567 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 5.932835e-01 0.227 0 0
Neurodegenerative Diseases R-HSA-8863678 2.457136e-01 0.610 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.457136e-01 0.610 0 0
Reproduction R-HSA-1474165 3.670481e-01 0.435 0 0
Formation of the anterior neural plate R-HSA-9823739 3.555446e-01 0.449 0 0
Diseases of DNA repair R-HSA-9675135 2.589282e-01 0.587 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 4.569754e-01 0.340 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 3.065893e-01 0.513 0 0
Interleukin-18 signaling R-HSA-9012546 3.470834e-01 0.460 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 4.879417e-01 0.312 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 4.879417e-01 0.312 0 0
Dopamine receptors R-HSA-390651 4.879417e-01 0.312 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 3.305763e-01 0.481 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 5.420035e-01 0.266 0 0
NrCAM interactions R-HSA-447038 5.420035e-01 0.266 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 5.420035e-01 0.266 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.888482e-01 0.539 0 0
SARS-CoV-1-host interactions R-HSA-9692914 2.501758e-01 0.602 0 0
Estrogen biosynthesis R-HSA-193144 5.326559e-01 0.274 0 0
Acetylcholine inhibits contraction of outer hair cells R-HSA-9667769 5.903605e-01 0.229 0 0
CREB phosphorylation R-HSA-199920 6.336143e-01 0.198 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 6.336143e-01 0.198 0 0
NADPH regeneration R-HSA-389542 6.336143e-01 0.198 0 0
MAP kinase activation R-HSA-450294 6.485458e-01 0.188 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 5.175853e-01 0.286 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 3.960907e-01 0.402 0 0
Signaling by ALK in cancer R-HSA-9700206 4.569754e-01 0.340 0 0
RUNX2 regulates bone development R-HSA-8941326 3.482252e-01 0.458 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 2.246755e-01 0.648 0 0
Lipophagy R-HSA-9613354 3.867583e-01 0.413 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.626063e-01 0.335 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 5.903605e-01 0.229 0 0
Lipid particle organization R-HSA-8964572 6.336143e-01 0.198 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 6.119021e-01 0.213 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 6.254425e-01 0.204 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 6.254425e-01 0.204 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 2.563883e-01 0.591 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 4.392416e-01 0.357 0 0
G1/S-Specific Transcription R-HSA-69205 5.231842e-01 0.281 0 0
Interleukin-15 signaling R-HSA-8983432 5.326559e-01 0.274 0 0
Tandem pore domain potassium channels R-HSA-1296346 4.253361e-01 0.371 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 6.039827e-01 0.219 0 0
Specification of primordial germ cells R-HSA-9827857 4.443378e-01 0.352 0 0
P2Y receptors R-HSA-417957 5.961929e-01 0.225 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 4.817961e-01 0.317 0 0
Platelet sensitization by LDL R-HSA-432142 4.729108e-01 0.325 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 5.670116e-01 0.246 0 0
Signaling by Leptin R-HSA-2586552 4.253361e-01 0.371 0 0
SARS-CoV-1 Infection R-HSA-9678108 5.841148e-01 0.234 0 0
Interleukin-37 signaling R-HSA-9008059 2.170692e-01 0.663 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 4.729108e-01 0.325 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 6.039827e-01 0.219 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 6.499675e-01 0.187 0 0
Deadenylation of mRNA R-HSA-429947 6.499675e-01 0.187 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 6.499675e-01 0.187 0 0
Effects of PIP2 hydrolysis R-HSA-114508 6.514398e-01 0.186 0 0
Killing mechanisms R-HSA-9664420 6.530200e-01 0.185 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 6.530200e-01 0.185 0 0
Regulation of BACH1 activity R-HSA-9708530 6.530200e-01 0.185 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 6.530200e-01 0.185 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 6.530200e-01 0.185 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 6.530200e-01 0.185 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 6.530200e-01 0.185 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 6.531140e-01 0.185 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 6.540553e-01 0.184 0 0
Regulation of mitotic cell cycle R-HSA-453276 6.540553e-01 0.184 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 6.546665e-01 0.184 0 0
Depyrimidination R-HSA-73928 6.546665e-01 0.184 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.582345e-01 0.182 0 0
Orc1 removal from chromatin R-HSA-68949 6.586688e-01 0.181 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 6.586688e-01 0.181 0 0
Signaling by Interleukins R-HSA-449147 6.596961e-01 0.181 0 0
Signaling by PDGF R-HSA-186797 6.630241e-01 0.178 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 6.675264e-01 0.176 0 0
Dual Incision in GG-NER R-HSA-5696400 6.701694e-01 0.174 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 6.701694e-01 0.174 0 0
NOD1/2 Signaling Pathway R-HSA-168638 6.701694e-01 0.174 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 6.701694e-01 0.174 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 6.714834e-01 0.173 0 0
Regulation of PTEN localization R-HSA-8948747 6.723032e-01 0.172 0 0
IFNG signaling activates MAPKs R-HSA-9732724 6.723032e-01 0.172 0 0
TRIF-mediated programmed cell death R-HSA-2562578 6.723032e-01 0.172 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 6.723032e-01 0.172 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 6.723032e-01 0.172 0 0
mRNA Editing: C to U Conversion R-HSA-72200 6.723032e-01 0.172 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 6.723032e-01 0.172 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 6.723032e-01 0.172 0 0
CHL1 interactions R-HSA-447041 6.723032e-01 0.172 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 6.723032e-01 0.172 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 6.723032e-01 0.172 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 6.746963e-01 0.171 0 0
Signaling by PTK6 R-HSA-8848021 6.771328e-01 0.169 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 6.771328e-01 0.169 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 6.789522e-01 0.168 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 6.789522e-01 0.168 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 6.789522e-01 0.168 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 6.789522e-01 0.168 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 6.789522e-01 0.168 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 6.789522e-01 0.168 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 6.789522e-01 0.168 0 0
Synthesis of PG R-HSA-1483148 6.789522e-01 0.168 0 0
Response to metal ions R-HSA-5660526 6.789522e-01 0.168 0 0
Circadian clock R-HSA-9909396 6.790467e-01 0.168 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.806770e-01 0.167 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 6.854513e-01 0.164 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 6.876493e-01 0.163 0 0
Myogenesis R-HSA-525793 6.920110e-01 0.160 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 6.920110e-01 0.160 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 6.920110e-01 0.160 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 6.959939e-01 0.157 0 0
Selenocysteine synthesis R-HSA-2408557 7.029531e-01 0.153 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 7.032790e-01 0.153 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 7.032790e-01 0.153 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 7.032790e-01 0.153 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 7.032790e-01 0.153 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 7.033152e-01 0.153 0 0
Fanconi Anemia Pathway R-HSA-6783310 7.033152e-01 0.153 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 7.055089e-01 0.151 0 0
ISG15 antiviral mechanism R-HSA-1169408 7.059922e-01 0.151 0 0
TCR signaling R-HSA-202403 7.063203e-01 0.151 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 7.069088e-01 0.151 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 7.069088e-01 0.151 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 7.069088e-01 0.151 0 0
Activation of RAS in B cells R-HSA-1169092 7.069088e-01 0.151 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 7.069088e-01 0.151 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 7.069088e-01 0.151 0 0
Regulation by c-FLIP R-HSA-3371378 7.069088e-01 0.151 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 7.069088e-01 0.151 0 0
TGFBR3 PTM regulation R-HSA-9839383 7.069088e-01 0.151 0 0
Dimerization of procaspase-8 R-HSA-69416 7.069088e-01 0.151 0 0
Sodium/Proton exchangers R-HSA-425986 7.069088e-01 0.151 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 7.069088e-01 0.151 0 0
Cristae formation R-HSA-8949613 7.115560e-01 0.148 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.170964e-01 0.144 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 7.170964e-01 0.144 0 0
Interleukin-12 signaling R-HSA-9020591 7.181478e-01 0.144 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 7.193925e-01 0.143 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 7.193925e-01 0.143 0 0
Degradation of DVL R-HSA-4641258 7.221152e-01 0.141 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 7.221152e-01 0.141 0 0
Cleavage of the damaged purine R-HSA-110331 7.221152e-01 0.141 0 0
Viral mRNA Translation R-HSA-192823 7.238935e-01 0.140 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 7.254439e-01 0.139 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 7.260504e-01 0.139 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 7.260504e-01 0.139 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 7.260504e-01 0.139 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 7.260504e-01 0.139 0 0
PKA activation R-HSA-163615 7.260504e-01 0.139 0 0
Apoptotic factor-mediated response R-HSA-111471 7.260504e-01 0.139 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 7.260504e-01 0.139 0 0
PKA activation in glucagon signalling R-HSA-164378 7.260504e-01 0.139 0 0
Presynaptic function of Kainate receptors R-HSA-500657 7.260504e-01 0.139 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 7.260504e-01 0.139 0 0
Tie2 Signaling R-HSA-210993 7.260504e-01 0.139 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 7.260504e-01 0.139 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 7.260504e-01 0.139 0 0
GAB1 signalosome R-HSA-180292 7.260504e-01 0.139 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.301301e-01 0.137 0 0
Pyroptosis R-HSA-5620971 7.301301e-01 0.137 0 0
Regulation of CDH1 Function R-HSA-9764561 7.305653e-01 0.136 0 0
IRS-mediated signalling R-HSA-112399 7.305653e-01 0.136 0 0
Recycling pathway of L1 R-HSA-437239 7.329795e-01 0.135 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 7.339980e-01 0.134 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 7.359735e-01 0.133 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 7.378617e-01 0.132 0 0
Interleukin-21 signaling R-HSA-9020958 7.378617e-01 0.132 0 0
WNT mediated activation of DVL R-HSA-201688 7.378617e-01 0.132 0 0
CASP8 activity is inhibited R-HSA-5218900 7.378617e-01 0.132 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 7.378617e-01 0.132 0 0
Interleukin-1 processing R-HSA-448706 7.378617e-01 0.132 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 7.378617e-01 0.132 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 7.378617e-01 0.132 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 7.378617e-01 0.132 0 0
mRNA Editing R-HSA-75072 7.378617e-01 0.132 0 0
Regulated proteolysis of p75NTR R-HSA-193692 7.378617e-01 0.132 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 7.378617e-01 0.132 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 7.378617e-01 0.132 0 0
Cellular response to mitochondrial stress R-HSA-9840373 7.378617e-01 0.132 0 0
Elastic fibre formation R-HSA-1566948 7.380163e-01 0.132 0 0
Depurination R-HSA-73927 7.380163e-01 0.132 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 7.423384e-01 0.129 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.471789e-01 0.127 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.471789e-01 0.127 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 7.473234e-01 0.126 0 0
Regulation of signaling by CBL R-HSA-912631 7.473234e-01 0.126 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 7.473234e-01 0.126 0 0
STING mediated induction of host immune responses R-HSA-1834941 7.473234e-01 0.126 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 7.473234e-01 0.126 0 0
Signaling by Erythropoietin R-HSA-9006335 7.477499e-01 0.126 0 0
mRNA Capping R-HSA-72086 7.477499e-01 0.126 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.477499e-01 0.126 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 7.477499e-01 0.126 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 7.477499e-01 0.126 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 7.532189e-01 0.123 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 7.532189e-01 0.123 0 0
Nucleotide Excision Repair R-HSA-5696398 7.534666e-01 0.123 0 0
Metabolism of non-coding RNA R-HSA-194441 7.561268e-01 0.121 0 0
snRNP Assembly R-HSA-191859 7.561268e-01 0.121 0 0
Adipogenesis R-HSA-9843745 7.576243e-01 0.121 0 0
Adaptive Immune System R-HSA-1280218 7.596478e-01 0.119 0 0
Signaling by MET R-HSA-6806834 7.633666e-01 0.117 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 7.635973e-01 0.117 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 7.644364e-01 0.117 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 7.644364e-01 0.117 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.644364e-01 0.117 0 0
Interleukin-17 signaling R-HSA-448424 7.651193e-01 0.116 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 7.655474e-01 0.116 0 0
DNA replication initiation R-HSA-68952 7.655474e-01 0.116 0 0
Regulation of the apoptosome activity R-HSA-9627069 7.655474e-01 0.116 0 0
Formation of apoptosome R-HSA-111458 7.655474e-01 0.116 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 7.655474e-01 0.116 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 7.655474e-01 0.116 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 7.655474e-01 0.116 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 7.655474e-01 0.116 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 7.655474e-01 0.116 0 0
Maturation of spike protein R-HSA-9683686 7.655474e-01 0.116 0 0
Defective factor IX causes hemophilia B R-HSA-9668250 7.655474e-01 0.116 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 7.655474e-01 0.116 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 7.655474e-01 0.116 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 7.671605e-01 0.115 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 7.671605e-01 0.115 0 0
Nephrin family interactions R-HSA-373753 7.671605e-01 0.115 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 7.677327e-01 0.115 0 0
Synthesis of DNA R-HSA-69239 7.719420e-01 0.112 0 0
PI3K Cascade R-HSA-109704 7.733287e-01 0.112 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 7.798664e-01 0.108 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 7.802136e-01 0.108 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 7.808069e-01 0.107 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 7.815694e-01 0.107 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 7.821701e-01 0.107 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 7.856276e-01 0.105 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 7.856276e-01 0.105 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 7.856276e-01 0.105 0 0
ERK/MAPK targets R-HSA-198753 7.856276e-01 0.105 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 7.867539e-01 0.104 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 7.903105e-01 0.102 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 7.903105e-01 0.102 0 0
Bicarbonate transporters R-HSA-425381 7.903105e-01 0.102 0 0
Transport of RCbl within the body R-HSA-9758890 7.903105e-01 0.102 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.903105e-01 0.102 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 7.903105e-01 0.102 0 0
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290 7.903105e-01 0.102 0 0
NCAM signaling for neurite out-growth R-HSA-375165 7.910628e-01 0.102 0 0
DNA Replication R-HSA-69306 7.912443e-01 0.102 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 7.947431e-01 0.100 0 0
HIV Transcription Initiation R-HSA-167161 7.947431e-01 0.100 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 7.947431e-01 0.100 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 7.947431e-01 0.100 0 0
Intra-Golgi traffic R-HSA-6811438 7.947431e-01 0.100 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 7.951088e-01 0.100 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 7.975254e-01 0.098 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 7.975254e-01 0.098 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 7.975254e-01 0.098 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 8.027928e-01 0.095 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 8.027928e-01 0.095 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 8.027928e-01 0.095 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 8.027928e-01 0.095 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 8.072694e-01 0.093 0 0
Smooth Muscle Contraction R-HSA-445355 8.088384e-01 0.092 0 0
Regulation of necroptotic cell death R-HSA-5675482 8.091511e-01 0.092 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 8.091511e-01 0.092 0 0
Insulin receptor signalling cascade R-HSA-74751 8.121389e-01 0.090 0 0
IGF1R signaling cascade R-HSA-2428924 8.121389e-01 0.090 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 8.124594e-01 0.090 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 8.124594e-01 0.090 0 0
Negative regulation of TCF-dependent signaling by WNT ligand antagonists R-HSA-3772470 8.124594e-01 0.090 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 8.124594e-01 0.090 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 8.124594e-01 0.090 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 8.124594e-01 0.090 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 8.124594e-01 0.090 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 8.124594e-01 0.090 0 0
Uptake of dietary cobalamins into enterocytes R-HSA-9758881 8.124594e-01 0.090 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 8.187250e-01 0.087 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 8.187250e-01 0.087 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 8.191655e-01 0.087 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 8.196421e-01 0.086 0 0
Cellular response to heat stress R-HSA-3371556 8.201004e-01 0.086 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 8.220331e-01 0.085 0 0
Cellular response to hypoxia R-HSA-1234174 8.220331e-01 0.085 0 0
Striated Muscle Contraction R-HSA-390522 8.223713e-01 0.085 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 8.223713e-01 0.085 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 8.223713e-01 0.085 0 0
Miscellaneous transport and binding events R-HSA-5223345 8.223713e-01 0.085 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 8.248986e-01 0.084 0 0
PTEN Regulation R-HSA-6807070 8.254538e-01 0.083 0 0
UCH proteinases R-HSA-5689603 8.254769e-01 0.083 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 8.259730e-01 0.083 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 8.295094e-01 0.081 0 0
Proteasome assembly R-HSA-9907900 8.304497e-01 0.081 0 0
Gastrulation R-HSA-9758941 8.314399e-01 0.080 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 8.322699e-01 0.080 0 0
GRB2 events in EGFR signaling R-HSA-179812 8.322699e-01 0.080 0 0
Scavenging by Class F Receptors R-HSA-3000484 8.322699e-01 0.080 0 0
IRAK1 recruits IKK complex R-HSA-937039 8.322699e-01 0.080 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 8.322699e-01 0.080 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 8.322699e-01 0.080 0 0
MET activates RAS signaling R-HSA-8851805 8.322699e-01 0.080 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 8.322699e-01 0.080 0 0
p75NTR recruits signalling complexes R-HSA-209543 8.322699e-01 0.080 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 8.322699e-01 0.080 0 0
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286 8.322699e-01 0.080 0 0
Diseases associated with surfactant metabolism R-HSA-5687613 8.322699e-01 0.080 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 8.322699e-01 0.080 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 8.322699e-01 0.080 0 0
VLDLR internalisation and degradation R-HSA-8866427 8.322699e-01 0.080 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 8.322699e-01 0.080 0 0
OAS antiviral response R-HSA-8983711 8.322699e-01 0.080 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 8.322699e-01 0.080 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 8.334932e-01 0.079 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 8.334932e-01 0.079 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 8.334932e-01 0.079 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 8.334932e-01 0.079 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 8.334932e-01 0.079 0 0
Syndecan interactions R-HSA-3000170 8.334932e-01 0.079 0 0
Growth hormone receptor signaling R-HSA-982772 8.334932e-01 0.079 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.348016e-01 0.078 0 0
Nuclear import of Rev protein R-HSA-180746 8.348016e-01 0.078 0 0
Signal amplification R-HSA-392518 8.348016e-01 0.078 0 0
Mitophagy R-HSA-5205647 8.348016e-01 0.078 0 0
Ion channel transport R-HSA-983712 8.370190e-01 0.077 0 0
Signaling by TGFB family members R-HSA-9006936 8.371813e-01 0.077 0 0
Interleukin-12 family signaling R-HSA-447115 8.376586e-01 0.077 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 8.383761e-01 0.077 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 8.397702e-01 0.076 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 8.411413e-01 0.075 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.411413e-01 0.075 0 0
Platelet homeostasis R-HSA-418346 8.455077e-01 0.073 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 8.464749e-01 0.072 0 0
Regulation of Apoptosis R-HSA-169911 8.464749e-01 0.072 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 8.471653e-01 0.072 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 8.471653e-01 0.072 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 8.471653e-01 0.072 0 0
Synthesis of dolichyl-phosphate R-HSA-446199 8.471653e-01 0.072 0 0
TNFs bind their physiological receptors R-HSA-5669034 8.471653e-01 0.072 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 8.482863e-01 0.071 0 0
Regulated Necrosis R-HSA-5218859 8.492452e-01 0.071 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 8.499889e-01 0.071 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 8.499889e-01 0.071 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 8.499889e-01 0.071 0 0
Chylomicron remodeling R-HSA-8963901 8.499889e-01 0.071 0 0
Mtb iron assimilation by chelation R-HSA-1222449 8.499889e-01 0.071 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 8.499889e-01 0.071 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 8.499889e-01 0.071 0 0
Formation of axial mesoderm R-HSA-9796292 8.499889e-01 0.071 0 0
CD28 dependent Vav1 pathway R-HSA-389359 8.499889e-01 0.071 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 8.499889e-01 0.071 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 8.499889e-01 0.071 0 0
Maturation of nucleoprotein R-HSA-9683610 8.499889e-01 0.071 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 8.512604e-01 0.070 0 0
Regulation of TNFR1 signaling R-HSA-5357905 8.512604e-01 0.070 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 8.537310e-01 0.069 0 0
Organelle biogenesis and maintenance R-HSA-1852241 8.549986e-01 0.068 0 0
Triglyceride catabolism R-HSA-163560 8.574244e-01 0.067 0 0
HSF1 activation R-HSA-3371511 8.574244e-01 0.067 0 0
Glycosphingolipid transport R-HSA-9845576 8.574244e-01 0.067 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 8.584510e-01 0.066 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 8.598081e-01 0.066 0 0
Acyl chain remodelling of PS R-HSA-1482801 8.598081e-01 0.066 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 8.598081e-01 0.066 0 0
Base Excision Repair R-HSA-73884 8.602708e-01 0.065 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 8.608275e-01 0.065 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 8.608275e-01 0.065 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 8.608275e-01 0.065 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 8.658369e-01 0.063 0 0
CRMPs in Sema3A signaling R-HSA-399956 8.658369e-01 0.063 0 0
The activation of arylsulfatases R-HSA-1663150 8.658369e-01 0.063 0 0
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661 8.658369e-01 0.063 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 8.658369e-01 0.063 0 0
Physiological factors R-HSA-5578768 8.658369e-01 0.063 0 0
NRIF signals cell death from the nucleus R-HSA-205043 8.658369e-01 0.063 0 0
Malate-aspartate shuttle R-HSA-9856872 8.658369e-01 0.063 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 8.658369e-01 0.063 0 0
HDL assembly R-HSA-8963896 8.658369e-01 0.063 0 0
Signal regulatory protein family interactions R-HSA-391160 8.658369e-01 0.063 0 0
Amyloid fiber formation R-HSA-977225 8.658514e-01 0.063 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 8.664649e-01 0.062 0 0
Triglyceride metabolism R-HSA-8979227 8.664649e-01 0.062 0 0
Degradation of AXIN R-HSA-4641257 8.676836e-01 0.062 0 0
SLC-mediated transport of organic cations R-HSA-549127 8.676836e-01 0.062 0 0
NCAM1 interactions R-HSA-419037 8.676836e-01 0.062 0 0
Intraflagellar transport R-HSA-5620924 8.698635e-01 0.061 0 0
Metal ion SLC transporters R-HSA-425410 8.698635e-01 0.061 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 8.714865e-01 0.060 0 0
Metalloprotease DUBs R-HSA-5689901 8.714865e-01 0.060 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 8.714865e-01 0.060 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 8.715945e-01 0.060 0 0
MyD88-independent TLR4 cascade R-HSA-166166 8.715945e-01 0.060 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.729603e-01 0.059 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.772857e-01 0.057 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 8.772857e-01 0.057 0 0
DNA Damage Bypass R-HSA-73893 8.783895e-01 0.056 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 8.800115e-01 0.056 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 8.800115e-01 0.056 0 0
G beta:gamma signalling through BTK R-HSA-8964315 8.800115e-01 0.056 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 8.800115e-01 0.056 0 0
Translesion synthesis by REV1 R-HSA-110312 8.800115e-01 0.056 0 0
SHC1 events in EGFR signaling R-HSA-180336 8.800115e-01 0.056 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 8.800115e-01 0.056 0 0
p75NTR signals via NF-kB R-HSA-193639 8.800115e-01 0.056 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 8.800115e-01 0.056 0 0
Spry regulation of FGF signaling R-HSA-1295596 8.800115e-01 0.056 0 0
DNA Damage Reversal R-HSA-73942 8.800115e-01 0.056 0 0
Ribosome-associated quality control R-HSA-9948299 8.800271e-01 0.056 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 8.820971e-01 0.054 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 8.822631e-01 0.054 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 8.822631e-01 0.054 0 0
Signaling by FGFR3 in disease R-HSA-5655332 8.822631e-01 0.054 0 0
Triglyceride biosynthesis R-HSA-75109 8.822631e-01 0.054 0 0
Synthesis of PE R-HSA-1483213 8.822631e-01 0.054 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 8.822631e-01 0.054 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 8.830216e-01 0.054 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 8.862637e-01 0.052 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.863838e-01 0.052 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.864267e-01 0.052 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 8.893086e-01 0.051 0 0
tRNA processing in the nucleus R-HSA-6784531 8.893086e-01 0.051 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 8.893086e-01 0.051 0 0
Hemostasis R-HSA-109582 8.907793e-01 0.050 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 8.921979e-01 0.050 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 8.921979e-01 0.050 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.921979e-01 0.050 0 0
Translesion synthesis by POLI R-HSA-5656121 8.926893e-01 0.049 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 8.926893e-01 0.049 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 8.926893e-01 0.049 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 8.926893e-01 0.049 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 8.926893e-01 0.049 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 8.926893e-01 0.049 0 0
Activation of SMO R-HSA-5635838 8.926893e-01 0.049 0 0
Fructose catabolism R-HSA-70350 8.926893e-01 0.049 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 8.926893e-01 0.049 0 0
Atorvastatin ADME R-HSA-9754706 8.926893e-01 0.049 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 8.928671e-01 0.049 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 8.939963e-01 0.049 0 0
Hedgehog ligand biogenesis R-HSA-5358346 8.939963e-01 0.049 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 8.940079e-01 0.049 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 8.946500e-01 0.048 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 8.946500e-01 0.048 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 8.946500e-01 0.048 0 0
Attenuation phase R-HSA-3371568 8.946500e-01 0.048 0 0
Glycogen metabolism R-HSA-8982491 8.946500e-01 0.048 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 8.946500e-01 0.048 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 8.961372e-01 0.048 0 0
rRNA processing R-HSA-72312 8.993007e-01 0.046 0 0
Protein ubiquitination R-HSA-8852135 8.996506e-01 0.046 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 9.011190e-01 0.045 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.011190e-01 0.045 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 9.013486e-01 0.045 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 9.013486e-01 0.045 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 9.013486e-01 0.045 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 9.013486e-01 0.045 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 9.013486e-01 0.045 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 9.013486e-01 0.045 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.013486e-01 0.045 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.017060e-01 0.045 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 9.024764e-01 0.045 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.024764e-01 0.045 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.024764e-01 0.045 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 9.025980e-01 0.045 0 0
Late Phase of HIV Life Cycle R-HSA-162599 9.036121e-01 0.044 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.039409e-01 0.044 0 0
Translesion synthesis by POLK R-HSA-5655862 9.040282e-01 0.044 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 9.040282e-01 0.044 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.040282e-01 0.044 0 0
Vitamin B6 activation to pyridoxal phosphate R-HSA-964975 9.040282e-01 0.044 0 0
Passive transport by Aquaporins R-HSA-432047 9.040282e-01 0.044 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 9.040282e-01 0.044 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 9.040282e-01 0.044 0 0
Coenzyme A biosynthesis R-HSA-196783 9.040282e-01 0.044 0 0
tRNA modification in the mitochondrion R-HSA-6787450 9.040282e-01 0.044 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 9.040282e-01 0.044 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.043898e-01 0.044 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 9.078156e-01 0.042 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.078156e-01 0.042 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 9.078156e-01 0.042 0 0
Clathrin-mediated endocytosis R-HSA-8856828 9.078384e-01 0.042 0 0
COPI-mediated anterograde transport R-HSA-6807878 9.083061e-01 0.042 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.086082e-01 0.042 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.095039e-01 0.041 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 9.097698e-01 0.041 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 9.097698e-01 0.041 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.097735e-01 0.041 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.115622e-01 0.040 0 0
Gene Silencing by RNA R-HSA-211000 9.128600e-01 0.040 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 9.134213e-01 0.039 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.141063e-01 0.039 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 9.141696e-01 0.039 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 9.141696e-01 0.039 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 9.141696e-01 0.039 0 0
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265 9.141696e-01 0.039 0 0
Glycogen storage diseases R-HSA-3229121 9.141696e-01 0.039 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 9.141696e-01 0.039 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 9.141696e-01 0.039 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 9.141696e-01 0.039 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 9.141696e-01 0.039 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 9.141696e-01 0.039 0 0
PCP/CE pathway R-HSA-4086400 9.163718e-01 0.038 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 9.175136e-01 0.037 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 9.175136e-01 0.037 0 0
Budding and maturation of HIV virion R-HSA-162588 9.175136e-01 0.037 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.175136e-01 0.037 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 9.200110e-01 0.036 0 0
Signaling by FGFR4 R-HSA-5654743 9.228993e-01 0.035 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.228993e-01 0.035 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 9.228993e-01 0.035 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 9.232399e-01 0.035 0 0
Biosynthesis of Lipoxins (LX) R-HSA-2142700 9.232399e-01 0.035 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 9.232399e-01 0.035 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 9.232399e-01 0.035 0 0
Cellular response to starvation R-HSA-9711097 9.242756e-01 0.034 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.246289e-01 0.034 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 9.255492e-01 0.034 0 0
Signaling by FGFR2 R-HSA-5654738 9.261214e-01 0.033 0 0
Influenza Infection R-HSA-168255 9.267499e-01 0.033 0 0
Interferon gamma signaling R-HSA-877300 9.276291e-01 0.033 0 0
Transmission across Chemical Synapses R-HSA-112315 9.282415e-01 0.032 0 0
Amine ligand-binding receptors R-HSA-375280 9.287846e-01 0.032 0 0
Surfactant metabolism R-HSA-5683826 9.287846e-01 0.032 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 9.305536e-01 0.031 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 9.311622e-01 0.031 0 0
Defective B3GALTL causes PpS R-HSA-5083635 9.311622e-01 0.031 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 9.311622e-01 0.031 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 9.313521e-01 0.031 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 9.313521e-01 0.031 0 0
Translesion Synthesis by POLH R-HSA-110320 9.313521e-01 0.031 0 0
Pyrimidine biosynthesis R-HSA-500753 9.313521e-01 0.031 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 9.313521e-01 0.031 0 0
E2F mediated regulation of DNA replication R-HSA-113510 9.313521e-01 0.031 0 0
The NLRP3 inflammasome R-HSA-844456 9.313521e-01 0.031 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 9.313521e-01 0.031 0 0
Other interleukin signaling R-HSA-449836 9.313521e-01 0.031 0 0
Diseases of hemostasis R-HSA-9671793 9.313521e-01 0.031 0 0
Maturation of nucleoprotein R-HSA-9694631 9.313521e-01 0.031 0 0
Inositol phosphate metabolism R-HSA-1483249 9.333126e-01 0.030 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.342543e-01 0.030 0 0
Signaling by FGFR3 R-HSA-5654741 9.342543e-01 0.030 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.342543e-01 0.030 0 0
Somitogenesis R-HSA-9824272 9.342543e-01 0.030 0 0
Dual incision in TC-NER R-HSA-6782135 9.356006e-01 0.029 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 9.368619e-01 0.028 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 9.371570e-01 0.028 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.371570e-01 0.028 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 9.371570e-01 0.028 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.371570e-01 0.028 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 9.386075e-01 0.028 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 9.386075e-01 0.028 0 0
Glycogen synthesis R-HSA-3322077 9.386075e-01 0.028 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 9.386075e-01 0.028 0 0
Signal transduction by L1 R-HSA-445144 9.386075e-01 0.028 0 0
Pregnenolone biosynthesis R-HSA-196108 9.386075e-01 0.028 0 0
Negative regulation of MET activity R-HSA-6807004 9.386075e-01 0.028 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.388705e-01 0.027 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.393341e-01 0.027 0 0
Response of endothelial cells to shear stress R-HSA-9860931 9.415139e-01 0.026 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 9.426540e-01 0.026 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.426540e-01 0.026 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.426540e-01 0.026 0 0
Signaling by NOTCH2 R-HSA-1980145 9.426540e-01 0.026 0 0
Cytokine Signaling in Immune system R-HSA-1280215 9.428862e-01 0.026 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 9.450964e-01 0.025 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 9.450964e-01 0.025 0 0
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896 9.450964e-01 0.025 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 9.450964e-01 0.025 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 9.450964e-01 0.025 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 9.450964e-01 0.025 0 0
Phenylalanine metabolism R-HSA-8964208 9.450964e-01 0.025 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 9.450964e-01 0.025 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 9.450964e-01 0.025 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 9.450964e-01 0.025 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 9.450964e-01 0.025 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 9.450964e-01 0.025 0 0
Basigin interactions R-HSA-210991 9.450964e-01 0.025 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 9.476915e-01 0.023 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.476915e-01 0.023 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.476915e-01 0.023 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.476915e-01 0.023 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.476915e-01 0.023 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 9.476915e-01 0.023 0 0
Vesicle-mediated transport R-HSA-5653656 9.478938e-01 0.023 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.483807e-01 0.023 0 0
Aquaporin-mediated transport R-HSA-445717 9.483807e-01 0.023 0 0
GPER1 signaling R-HSA-9634597 9.484203e-01 0.023 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.496219e-01 0.022 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.499793e-01 0.022 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 9.508998e-01 0.022 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 9.508998e-01 0.022 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 9.508998e-01 0.022 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.523051e-01 0.021 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.523051e-01 0.021 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.525020e-01 0.021 0 0
HIV Life Cycle R-HSA-162587 9.525020e-01 0.021 0 0
Co-inhibition by PD-1 R-HSA-389948 9.534877e-01 0.021 0 0
Mitochondrial biogenesis R-HSA-1592230 9.548854e-01 0.020 0 0
Phospholipid metabolism R-HSA-1483257 9.550427e-01 0.020 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.560901e-01 0.020 0 0
Biosynthesis of D-series resolvins R-HSA-9018676 9.560901e-01 0.020 0 0
Fructose metabolism R-HSA-5652084 9.560901e-01 0.020 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 9.560901e-01 0.020 0 0
Ethanol oxidation R-HSA-71384 9.560901e-01 0.020 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.560901e-01 0.020 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 9.560901e-01 0.020 0 0
O-glycosylation of TSR domain-containing proteins R-HSA-5173214 9.565283e-01 0.019 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.565283e-01 0.019 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 9.565283e-01 0.019 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.565283e-01 0.019 0 0
Ion transport by P-type ATPases R-HSA-936837 9.587950e-01 0.018 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.596993e-01 0.018 0 0
The phototransduction cascade R-HSA-2514856 9.596993e-01 0.018 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.607320e-01 0.017 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 9.607320e-01 0.017 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 9.607320e-01 0.017 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 9.607320e-01 0.017 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.607320e-01 0.017 0 0
Organic anion transport by SLCO transporters R-HSA-879518 9.607320e-01 0.017 0 0
Biosynthesis of maresins R-HSA-9018682 9.607320e-01 0.017 0 0
ER-Phagosome pathway R-HSA-1236974 9.613039e-01 0.017 0 0
Potential therapeutics for SARS R-HSA-9679191 9.615241e-01 0.017 0 0
Glycolysis R-HSA-70171 9.634507e-01 0.016 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 9.634935e-01 0.016 0 0
Downstream TCR signaling R-HSA-202424 9.638102e-01 0.016 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.639247e-01 0.016 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.641321e-01 0.016 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 9.648834e-01 0.016 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.648834e-01 0.016 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 9.648834e-01 0.016 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.648834e-01 0.016 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.648834e-01 0.016 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.648834e-01 0.016 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.648834e-01 0.016 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.658844e-01 0.015 0 0
SARS-CoV-2-host interactions R-HSA-9705683 9.666467e-01 0.015 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 9.671536e-01 0.015 0 0
Diseases of Immune System R-HSA-5260271 9.671536e-01 0.015 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 9.671536e-01 0.015 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.671536e-01 0.015 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.672347e-01 0.014 0 0
Signaling by NOTCH R-HSA-157118 9.683753e-01 0.014 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.685961e-01 0.014 0 0
G protein gated Potassium channels R-HSA-1296059 9.685961e-01 0.014 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 9.685961e-01 0.014 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 9.685961e-01 0.014 0 0
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives R-HSA-9027604 9.685961e-01 0.014 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 9.685961e-01 0.014 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.685961e-01 0.014 0 0
Maturation of spike protein R-HSA-9694548 9.701032e-01 0.013 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 9.701032e-01 0.013 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.701032e-01 0.013 0 0
Signaling by Insulin receptor R-HSA-74752 9.704653e-01 0.013 0 0
PPARA activates gene expression R-HSA-1989781 9.705032e-01 0.013 0 0
MET activates PTK2 signaling R-HSA-8874081 9.719166e-01 0.012 0 0
Signaling by EGFR in Cancer R-HSA-1643713 9.719166e-01 0.012 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 9.719166e-01 0.012 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.719166e-01 0.012 0 0
Abacavir ADME R-HSA-2161522 9.719166e-01 0.012 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 9.719166e-01 0.012 0 0
Sphingolipid catabolism R-HSA-9845614 9.719166e-01 0.012 0 0
Neddylation R-HSA-8951664 9.720815e-01 0.012 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.727965e-01 0.012 0 0
Translation of Structural Proteins R-HSA-9683701 9.727965e-01 0.012 0 0
Signaling by FGFR1 R-HSA-5654736 9.735069e-01 0.012 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.737503e-01 0.012 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 9.748861e-01 0.011 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 9.748861e-01 0.011 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.748861e-01 0.011 0 0
Biosynthesis of DPAn-3 SPMs R-HSA-9025094 9.748861e-01 0.011 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 9.748861e-01 0.011 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 9.748861e-01 0.011 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.748861e-01 0.011 0 0
Signaling by BMP R-HSA-201451 9.748861e-01 0.011 0 0
Insulin processing R-HSA-264876 9.748861e-01 0.011 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.752547e-01 0.011 0 0
Synthesis of PA R-HSA-1483166 9.756666e-01 0.011 0 0
Cellular responses to stress R-HSA-2262752 9.773015e-01 0.010 0 0
Defensins R-HSA-1461973 9.774974e-01 0.010 0 0
Prednisone ADME R-HSA-9757110 9.775418e-01 0.010 0 0
Inflammasomes R-HSA-622312 9.775418e-01 0.010 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 9.775418e-01 0.010 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.776582e-01 0.010 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 9.778138e-01 0.010 0 0
Glucose metabolism R-HSA-70326 9.779079e-01 0.010 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.794939e-01 0.009 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.795427e-01 0.009 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.797008e-01 0.009 0 0
Thyroxine biosynthesis R-HSA-209968 9.799167e-01 0.009 0 0
Regulation of gene expression in beta cells R-HSA-210745 9.799167e-01 0.009 0 0
Biosynthesis of EPA-derived SPMs R-HSA-9018679 9.799167e-01 0.009 0 0
Glucagon-type ligand receptors R-HSA-420092 9.799167e-01 0.009 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.799167e-01 0.009 0 0
Parasite infection R-HSA-9664407 9.804458e-01 0.009 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.804458e-01 0.009 0 0
Leishmania phagocytosis R-HSA-9664417 9.804458e-01 0.009 0 0
Signaling by NOTCH4 R-HSA-9013694 9.810666e-01 0.008 0 0
GABA receptor activation R-HSA-977443 9.811852e-01 0.008 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.811852e-01 0.008 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.811852e-01 0.008 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 9.814072e-01 0.008 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.814072e-01 0.008 0 0
Signaling by FGFR R-HSA-190236 9.818508e-01 0.008 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 9.820407e-01 0.008 0 0
Neurotransmitter clearance R-HSA-112311 9.820407e-01 0.008 0 0
Mucopolysaccharidoses R-HSA-2206281 9.820407e-01 0.008 0 0
Cellular responses to stimuli R-HSA-8953897 9.820697e-01 0.008 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 9.825187e-01 0.008 0 0
Viral Messenger RNA Synthesis R-HSA-168325 9.827427e-01 0.008 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 9.831063e-01 0.007 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.831063e-01 0.007 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.831063e-01 0.007 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 9.831063e-01 0.007 0 0
Cargo concentration in the ER R-HSA-5694530 9.839401e-01 0.007 0 0
Biosynthesis of DPA-derived SPMs R-HSA-9018683 9.839401e-01 0.007 0 0
Synthesis of glycosylphosphatidylinositol (GPI) R-HSA-162710 9.839401e-01 0.007 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.845074e-01 0.007 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 9.846541e-01 0.007 0 0
Synthesis of PC R-HSA-1483191 9.846541e-01 0.007 0 0
Complex I biogenesis R-HSA-6799198 9.854956e-01 0.006 0 0
Inwardly rectifying K+ channels R-HSA-1296065 9.856388e-01 0.006 0 0
Toll-like Receptor Cascades R-HSA-168898 9.862362e-01 0.006 0 0
Interleukin-10 signaling R-HSA-6783783 9.862679e-01 0.006 0 0
Cholesterol biosynthesis R-HSA-191273 9.862679e-01 0.006 0 0
Recycling of bile acids and salts R-HSA-159418 9.871579e-01 0.006 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.871579e-01 0.006 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.873378e-01 0.006 0 0
IRE1alpha activates chaperones R-HSA-381070 9.875721e-01 0.005 0 0
ER to Golgi Anterograde Transport R-HSA-199977 9.879793e-01 0.005 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.884885e-01 0.005 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 9.885163e-01 0.005 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.885163e-01 0.005 0 0
CS/DS degradation R-HSA-2024101 9.885163e-01 0.005 0 0
Glutamate and glutamine metabolism R-HSA-8964539 9.885163e-01 0.005 0 0
Developmental Cell Lineages R-HSA-9734767 9.892274e-01 0.005 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.892441e-01 0.005 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.897312e-01 0.004 0 0
Phosphate bond hydrolysis by NUDT proteins R-HSA-2393930 9.897312e-01 0.004 0 0
Metabolism of steroid hormones R-HSA-196071 9.897912e-01 0.004 0 0
Collagen formation R-HSA-1474290 9.901326e-01 0.004 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 9.906560e-01 0.004 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.906560e-01 0.004 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.908176e-01 0.004 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.908176e-01 0.004 0 0
Selenoamino acid metabolism R-HSA-2408522 9.910914e-01 0.004 0 0
Nucleotide biosynthesis R-HSA-8956320 9.914215e-01 0.004 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 9.917891e-01 0.004 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.917891e-01 0.004 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.921785e-01 0.003 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 9.922600e-01 0.003 0 0
Phenylalanine and tyrosine metabolism R-HSA-8963691 9.926579e-01 0.003 0 0
Collagen chain trimerization R-HSA-8948216 9.926579e-01 0.003 0 0
Metabolism of folate and pterines R-HSA-196757 9.926579e-01 0.003 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.928469e-01 0.003 0 0
Neutrophil degranulation R-HSA-6798695 9.929078e-01 0.003 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 9.929457e-01 0.003 0 0
Signaling by NOTCH3 R-HSA-9012852 9.929457e-01 0.003 0 0
Purine salvage R-HSA-74217 9.934348e-01 0.003 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 9.934348e-01 0.003 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.934539e-01 0.003 0 0
XBP1(S) activates chaperone genes R-HSA-381038 9.934539e-01 0.003 0 0
HIV Infection R-HSA-162906 9.935367e-01 0.003 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.936049e-01 0.003 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.941295e-01 0.003 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.941295e-01 0.003 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.941295e-01 0.003 0 0
Dectin-2 family R-HSA-5621480 9.942037e-01 0.003 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 9.951381e-01 0.002 0 0
Regulation of beta-cell development R-HSA-186712 9.952410e-01 0.002 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.952410e-01 0.002 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.953063e-01 0.002 0 0
Cellular response to chemical stress R-HSA-9711123 9.953601e-01 0.002 0 0
Platelet degranulation R-HSA-114608 9.956706e-01 0.002 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.956750e-01 0.002 0 0
Metabolism of polyamines R-HSA-351202 9.956890e-01 0.002 0 0
Translation of Structural Proteins R-HSA-9694635 9.958365e-01 0.002 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.961706e-01 0.002 0 0
RSV-host interactions R-HSA-9833110 9.961785e-01 0.002 0 0
ABC transporter disorders R-HSA-5619084 9.961987e-01 0.002 0 0
Integrin cell surface interactions R-HSA-216083 9.961987e-01 0.002 0 0
Activation of GABAB receptors R-HSA-991365 9.962473e-01 0.002 0 0
GABA B receptor activation R-HSA-977444 9.962473e-01 0.002 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.966445e-01 0.001 0 0
PKR-mediated signaling R-HSA-9833482 9.968335e-01 0.001 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 9.969145e-01 0.001 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.969997e-01 0.001 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.974233e-01 0.001 0 0
HCMV Early Events R-HSA-9609690 9.975704e-01 0.001 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.976014e-01 0.001 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.976263e-01 0.001 0 0
G alpha (s) signalling events R-HSA-418555 9.976405e-01 0.001 0 0
Nicotinate metabolism R-HSA-196807 9.978522e-01 0.001 0 0
GPCR downstream signalling R-HSA-388396 9.979114e-01 0.001 0 0
Host Interactions of HIV factors R-HSA-162909 9.979398e-01 0.001 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.980824e-01 0.001 0 0
Gluconeogenesis R-HSA-70263 9.980824e-01 0.001 0 0
Gap junction trafficking and regulation R-HSA-157858 9.982854e-01 0.001 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.982854e-01 0.001 0 0
ABC-family proteins mediated transport R-HSA-382556 9.983357e-01 0.001 0 0
Azathioprine ADME R-HSA-9748787 9.984670e-01 0.001 0 0
Chaperonin-mediated protein folding R-HSA-390466 9.984878e-01 0.001 0 0
Retinoid metabolism and transport R-HSA-975634 9.985624e-01 0.001 0 0
Complex IV assembly R-HSA-9864848 9.986294e-01 0.001 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.986867e-01 0.001 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.987002e-01 0.001 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.988249e-01 0.001 0 0
Parasitic Infection Pathways R-HSA-9824443 9.988517e-01 0.000 0 0
Leishmania infection R-HSA-9658195 9.988517e-01 0.000 0 0
Neurotransmitter release cycle R-HSA-112310 9.988575e-01 0.000 0 0
SARS-CoV Infections R-HSA-9679506 9.989051e-01 0.000 0 0
HCMV Late Events R-HSA-9610379 9.989733e-01 0.000 0 0
Iron uptake and transport R-HSA-917937 9.990399e-01 0.000 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.990399e-01 0.000 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.990399e-01 0.000 0 0
G alpha (z) signalling events R-HSA-418597 9.991241e-01 0.000 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.991241e-01 0.000 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.991381e-01 0.000 0 0
Protein folding R-HSA-391251 9.991381e-01 0.000 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 9.992076e-01 0.000 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.992169e-01 0.000 0 0
Digestion R-HSA-8935690 9.992169e-01 0.000 0 0
Interferon Signaling R-HSA-913531 9.992720e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.992864e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.992916e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.993614e-01 0.000 0 0
Formation of the cornified envelope R-HSA-6809371 9.993861e-01 0.000 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.994313e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.994630e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.994779e-01 0.000 0 0
RAB geranylgeranylation R-HSA-8873719 9.994997e-01 0.000 0 0
SLC transporter disorders R-HSA-5619102 9.995195e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.995252e-01 0.000 0 0
Endogenous sterols R-HSA-211976 9.995527e-01 0.000 0 0
Nucleotide salvage R-HSA-8956321 9.995527e-01 0.000 0 0
Collagen degradation R-HSA-1442490 9.995527e-01 0.000 0 0
Mitochondrial protein import R-HSA-1268020 9.996001e-01 0.000 0 0
Digestion and absorption R-HSA-8963743 9.996425e-01 0.000 0 0
tRNA processing R-HSA-72306 9.996472e-01 0.000 0 0
HCMV Infection R-HSA-9609646 9.996504e-01 0.000 0 0
Interferon alpha/beta signaling R-HSA-909733 9.996654e-01 0.000 0 0
G alpha (q) signalling events R-HSA-416476 9.996759e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.996804e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.997067e-01 0.000 0 0
Latent infection - Other responses of Mtb to phagocytosis R-HSA-1222499 9.997142e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.997210e-01 0.000 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.997401e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.997409e-01 0.000 0 0
Pyruvate metabolism R-HSA-70268 9.997448e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.997697e-01 0.000 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.997716e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.997730e-01 0.000 0 0
O-linked glycosylation of mucins R-HSA-913709 9.997958e-01 0.000 0 0
COPII-mediated vesicle transport R-HSA-204005 9.998368e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.998368e-01 0.000 0 0
ECM proteoglycans R-HSA-3000178 9.998541e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.998541e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.998696e-01 0.000 0 0
Unfolded Protein Response (UPR) R-HSA-381119 9.998716e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.998759e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.998819e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.998847e-01 0.000 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.998958e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999037e-01 0.000 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.999068e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999179e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999213e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999333e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999362e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.999399e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999424e-01 0.000 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.999525e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999603e-01 0.000 0 0
Immune System R-HSA-168256 9.999639e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999678e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999707e-01 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.999768e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.999776e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.999776e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999809e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.999828e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.999845e-01 0.000 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.999898e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999946e-01 0.000 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.999950e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999956e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999969e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999971e-01 0.000 0 0
Regulation of Complement cascade R-HSA-977606 9.999971e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999988e-01 0.000 0 0
Protein localization R-HSA-9609507 9.999990e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999994e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999995e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999996e-01 0.000 0 0
Translation R-HSA-72766 9.999997e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999997e-01 0.000 0 0
Complement cascade R-HSA-166658 9.999998e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999998e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999998e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999998e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999999e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999999e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999999e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.999999e-01 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 9.999999e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999999e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 1.000000e+00 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 1.000000e+00 0.000 0 0
Viral Infection Pathways R-HSA-9824446 1.000000e+00 0.000 0 0
Post-translational protein modification R-HSA-597592 1.000000e+00 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 1.000000e+00 0.000 0 0
Arachidonate metabolism R-HSA-2142753 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Disease R-HSA-1643685 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Infectious disease R-HSA-5663205 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Cellular responses to stress R-HSA-2262752 1.043610e-13 12.981 0 0
Cellular responses to stimuli R-HSA-8953897 2.686740e-13 12.571 0 0
M Phase R-HSA-68886 6.202816e-13 12.207 0 0
Cellular response to heat stress R-HSA-3371556 2.906564e-12 11.537 0 0
HSF1-dependent transactivation R-HSA-3371571 7.066125e-12 11.151 0 0
HSF1 activation R-HSA-3371511 8.571699e-12 11.067 0 0
Attenuation phase R-HSA-3371568 8.742229e-12 11.058 0 0
Cell Cycle R-HSA-1640170 1.932967e-10 9.714 0 0
Cell Cycle, Mitotic R-HSA-69278 3.709600e-10 9.431 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 4.870773e-10 9.312 0 0
Signal Transduction R-HSA-162582 2.314328e-09 8.636 0 0
Aggrephagy R-HSA-9646399 7.930507e-09 8.101 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.311580e-08 7.882 0 0
Mitotic Prometaphase R-HSA-68877 1.526227e-08 7.816 0 0
Chromatin modifying enzymes R-HSA-3247509 1.794399e-08 7.746 0 0
Chromatin organization R-HSA-4839726 2.051082e-08 7.688 0 0
Mitotic Anaphase R-HSA-68882 2.540476e-08 7.595 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.897863e-08 7.538 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 2.798089e-08 7.553 0 0
Nervous system development R-HSA-9675108 3.967889e-08 7.401 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.250470e-08 7.372 0 0
Cell junction organization R-HSA-446728 5.065447e-08 7.295 0 0
Cell Cycle Checkpoints R-HSA-69620 6.047250e-08 7.218 0 0
Cell-Cell communication R-HSA-1500931 5.955310e-08 7.225 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 6.397949e-08 7.194 0 0
Separation of Sister Chromatids R-HSA-2467813 6.309613e-08 7.200 0 0
Apoptotic execution phase R-HSA-75153 7.974355e-08 7.098 0 0
Axon guidance R-HSA-422475 9.590926e-08 7.018 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.025537e-07 6.989 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.025537e-07 6.989 0 0
Recycling pathway of L1 R-HSA-437239 1.074946e-07 6.969 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.385228e-07 6.858 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.464075e-07 6.834 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.705705e-07 6.768 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.824171e-07 6.739 0 0
Kinesins R-HSA-983189 2.252699e-07 6.647 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 2.604047e-07 6.584 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.784475e-07 6.555 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 2.792917e-07 6.554 0 0
Metabolism of RNA R-HSA-8953854 2.650600e-07 6.577 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 4.929152e-07 6.307 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 5.185069e-07 6.285 0 0
HDACs deacetylate histones R-HSA-3214815 9.310579e-07 6.031 0 0
Adherens junctions interactions R-HSA-418990 1.021557e-06 5.991 0 0
G2/M Checkpoints R-HSA-69481 1.087976e-06 5.963 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.452144e-06 5.838 0 0
Cell-cell junction organization R-HSA-421270 1.538274e-06 5.813 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.727538e-06 5.763 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.835961e-06 5.736 0 0
Mitotic Prophase R-HSA-68875 2.343854e-06 5.630 0 0
p75NTR signals via NF-kB R-HSA-193639 2.549402e-06 5.594 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.626531e-06 5.581 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.769710e-06 5.558 0 0
Selective autophagy R-HSA-9663891 2.769710e-06 5.558 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 3.065339e-06 5.514 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 3.380474e-06 5.471 0 0
L1CAM interactions R-HSA-373760 3.440941e-06 5.463 0 0
SARS-CoV-1-host interactions R-HSA-9692914 4.000192e-06 5.398 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 4.563484e-06 5.341 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 4.744974e-06 5.324 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.955303e-06 5.305 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 5.875611e-06 5.231 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 6.158402e-06 5.211 0 0
ESR-mediated signaling R-HSA-8939211 7.649971e-06 5.116 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 7.370427e-06 5.133 0 0
Epigenetic regulation of gene expression R-HSA-212165 8.592143e-06 5.066 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 8.313012e-06 5.080 0 0
Cellular Senescence R-HSA-2559583 8.465056e-06 5.072 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 8.783810e-06 5.056 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.025710e-05 4.989 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 1.017175e-05 4.993 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 9.953227e-06 5.002 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 1.025710e-05 4.989 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.105234e-05 4.957 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.062482e-05 4.974 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.056439e-05 4.976 0 0
mRNA Splicing R-HSA-72172 1.182301e-05 4.927 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.184567e-05 4.926 0 0
DNA Double Strand Break Response R-HSA-5693606 1.284672e-05 4.891 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.541730e-05 4.812 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.493117e-05 4.826 0 0
Nucleosome assembly R-HSA-774815 1.581248e-05 4.801 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.581248e-05 4.801 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.755758e-05 4.756 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 2.109330e-05 4.676 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.260141e-05 4.646 0 0
HATs acetylate histones R-HSA-3214847 2.353997e-05 4.628 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 2.470533e-05 4.607 0 0
p75NTR recruits signalling complexes R-HSA-209543 2.556826e-05 4.592 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 2.665481e-05 4.574 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 2.852103e-05 4.545 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.237328e-05 4.490 0 0
G2/M Transition R-HSA-69275 3.561450e-05 4.448 0 0
Regulation of endogenous retroelements R-HSA-9842860 3.652223e-05 4.437 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 4.334585e-05 4.363 0 0
Mitotic G2-G2/M phases R-HSA-453274 4.364769e-05 4.360 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 4.880315e-05 4.312 0 0
Death Receptor Signaling R-HSA-73887 5.329677e-05 4.273 0 0
Protein ubiquitination R-HSA-8852135 5.416769e-05 4.266 0 0
Eukaryotic Translation Initiation R-HSA-72613 5.778019e-05 4.238 0 0
Cap-dependent Translation Initiation R-HSA-72737 5.778019e-05 4.238 0 0
Post NMDA receptor activation events R-HSA-438064 5.541138e-05 4.256 0 0
Macroautophagy R-HSA-1632852 5.611418e-05 4.251 0 0
Signaling by Hippo R-HSA-2028269 5.479041e-05 4.261 0 0
Apoptosis R-HSA-109581 5.744188e-05 4.241 0 0
Regulation of CDH1 Function R-HSA-9764561 5.937679e-05 4.226 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 6.391291e-05 4.194 0 0
Autophagy R-HSA-9612973 6.630643e-05 4.178 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 7.175234e-05 4.144 0 0
PRC2 methylates histones and DNA R-HSA-212300 7.349382e-05 4.134 0 0
Chaperone Mediated Autophagy R-HSA-9613829 7.868844e-05 4.104 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 8.124521e-05 4.090 0 0
Meiotic synapsis R-HSA-1221632 8.716623e-05 4.060 0 0
RNA Polymerase I Transcription R-HSA-73864 8.820057e-05 4.055 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 9.498596e-05 4.022 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 9.498596e-05 4.022 0 0
HCMV Early Events R-HSA-9609690 9.504915e-05 4.022 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.498596e-05 4.022 0 0
Signaling by ROBO receptors R-HSA-376176 8.947948e-05 4.048 0 0
NF-kB is activated and signals survival R-HSA-209560 1.024109e-04 3.990 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.049636e-04 3.979 0 0
Translation initiation complex formation R-HSA-72649 1.055350e-04 3.977 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.109624e-04 3.955 0 0
Membrane Trafficking R-HSA-199991 1.128189e-04 3.948 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.272154e-04 3.895 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.203556e-04 3.920 0 0
Gap junction trafficking and regulation R-HSA-157858 1.279825e-04 3.893 0 0
Eukaryotic Translation Elongation R-HSA-156842 1.331402e-04 3.876 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.392654e-04 3.856 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.400235e-04 3.854 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.526997e-04 3.816 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.536165e-04 3.814 0 0
Gap junction trafficking R-HSA-190828 1.536876e-04 3.813 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.550920e-04 3.809 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.742833e-04 3.759 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.742833e-04 3.759 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.822284e-04 3.739 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.922606e-04 3.716 0 0
Developmental Biology R-HSA-1266738 1.843196e-04 3.734 0 0
Regulation of TP53 Activity R-HSA-5633007 2.155745e-04 3.666 0 0
Programmed Cell Death R-HSA-5357801 2.333595e-04 3.632 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 2.371709e-04 3.625 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 2.422949e-04 3.616 0 0
Meiosis R-HSA-1500620 2.500319e-04 3.602 0 0
DNA Replication Pre-Initiation R-HSA-69002 2.585923e-04 3.587 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.729997e-04 3.564 0 0
AURKA Activation by TPX2 R-HSA-8854518 2.842433e-04 3.546 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 2.932936e-04 3.533 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 3.068268e-04 3.513 0 0
Packaging Of Telomere Ends R-HSA-171306 3.451249e-04 3.462 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 3.451249e-04 3.462 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 3.582428e-04 3.446 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 3.681776e-04 3.434 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 3.681776e-04 3.434 0 0
Chaperonin-mediated protein folding R-HSA-390466 3.765399e-04 3.424 0 0
Assembly of the pre-replicative complex R-HSA-68867 3.802217e-04 3.420 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 3.855787e-04 3.414 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 3.855787e-04 3.414 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.084064e-04 3.389 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 4.206856e-04 3.376 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 4.745648e-04 3.324 0 0
TCF dependent signaling in response to WNT R-HSA-201681 4.767966e-04 3.322 0 0
Cell-extracellular matrix interactions R-HSA-446353 4.915067e-04 3.308 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 4.915067e-04 3.308 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 4.816712e-04 3.317 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.686671e-04 3.329 0 0
Nuclear Envelope Breakdown R-HSA-2980766 5.313552e-04 3.275 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 5.445811e-04 3.264 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 5.445811e-04 3.264 0 0
Formation of a pool of free 40S subunits R-HSA-72689 5.527333e-04 3.257 0 0
DNA methylation R-HSA-5334118 5.588111e-04 3.253 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.588111e-04 3.253 0 0
Signaling by NOTCH R-HSA-157118 5.634804e-04 3.249 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 5.650535e-04 3.248 0 0
Meiotic recombination R-HSA-912446 5.659170e-04 3.247 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 5.950042e-04 3.225 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 6.027409e-04 3.220 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 6.621358e-04 3.179 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 6.656786e-04 3.177 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 6.427114e-04 3.192 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.237020e-04 3.205 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.940465e-04 3.159 0 0
MHC class II antigen presentation R-HSA-2132295 6.844848e-04 3.165 0 0
Signaling downstream of RAS mutants R-HSA-9649948 7.068021e-04 3.151 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 7.068021e-04 3.151 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 7.068021e-04 3.151 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 7.068021e-04 3.151 0 0
Signaling by RAS mutants R-HSA-6802949 7.068021e-04 3.151 0 0
Amplification of signal from the kinetochores R-HSA-141424 7.157799e-04 3.145 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 7.157799e-04 3.145 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 7.299232e-04 3.137 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 7.972553e-04 3.098 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 7.972553e-04 3.098 0 0
Protein folding R-HSA-391251 8.046192e-04 3.094 0 0
Signaling by RAF1 mutants R-HSA-9656223 8.779215e-04 3.057 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.782385e-04 3.056 0 0
Homology Directed Repair R-HSA-5693538 8.818642e-04 3.055 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 8.935196e-04 3.049 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 8.935196e-04 3.049 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 9.321102e-04 3.031 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 9.321102e-04 3.031 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.082474e-03 2.966 0 0
Centrosome maturation R-HSA-380287 1.043565e-03 2.981 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.047520e-03 2.980 0 0
Peptide chain elongation R-HSA-156902 1.038653e-03 2.984 0 0
DNA Double-Strand Break Repair R-HSA-5693532 9.603174e-04 3.018 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 1.021156e-03 2.991 0 0
Cleavage of the damaged purine R-HSA-110331 1.082474e-03 2.966 0 0
Hedgehog 'off' state R-HSA-5610787 9.925576e-04 3.003 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 1.157186e-03 2.937 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.157186e-03 2.937 0 0
Interleukin-12 signaling R-HSA-9020591 1.189296e-03 2.925 0 0
Influenza Infection R-HSA-168255 1.272012e-03 2.896 0 0
Depurination R-HSA-73927 1.304816e-03 2.884 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.394993e-03 2.855 0 0
Ub-specific processing proteases R-HSA-5689880 1.491907e-03 2.826 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.544435e-03 2.811 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.544435e-03 2.811 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 1.607695e-03 2.794 0 0
Signaling by WNT R-HSA-195721 1.676058e-03 2.776 0 0
NRIF signals cell death from the nucleus R-HSA-205043 1.703489e-03 2.769 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.703489e-03 2.769 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 1.869930e-03 2.728 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.913103e-03 2.718 0 0
Signaling by VEGF R-HSA-194138 1.929688e-03 2.715 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 1.942979e-03 2.712 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 1.942979e-03 2.712 0 0
Gap junction assembly R-HSA-190861 1.942979e-03 2.712 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 2.229654e-03 2.652 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 2.298611e-03 2.639 0 0
Mitotic Spindle Checkpoint R-HSA-69618 2.202959e-03 2.657 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 2.185701e-03 2.660 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 2.298611e-03 2.639 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 2.208569e-03 2.656 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 2.223657e-03 2.653 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 2.298611e-03 2.639 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 2.314999e-03 2.635 0 0
Signaling by ALK in cancer R-HSA-9700206 2.314999e-03 2.635 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 2.047587e-03 2.689 0 0
Gene Silencing by RNA R-HSA-211000 2.314999e-03 2.635 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 2.298611e-03 2.639 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 2.333043e-03 2.632 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.391744e-03 2.621 0 0
Chromosome Maintenance R-HSA-73886 2.479110e-03 2.606 0 0
Gene expression (Transcription) R-HSA-74160 2.543658e-03 2.595 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 2.564425e-03 2.591 0 0
MAP2K and MAPK activation R-HSA-5674135 2.604360e-03 2.584 0 0
Regulation of PTEN localization R-HSA-8948747 2.679015e-03 2.572 0 0
Negative regulation of MET activity R-HSA-6807004 2.730383e-03 2.564 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 2.784211e-03 2.555 0 0
EGFR downregulation R-HSA-182971 2.899654e-03 2.538 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 2.983375e-03 2.525 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 3.055980e-03 2.515 0 0
Depyrimidination R-HSA-73928 3.055980e-03 2.515 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 3.122086e-03 2.506 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 3.122086e-03 2.506 0 0
Co-inhibition by PD-1 R-HSA-389948 3.294921e-03 2.482 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.295507e-03 2.482 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 3.303170e-03 2.481 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 3.303170e-03 2.481 0 0
Signaling by EGFR R-HSA-177929 3.306209e-03 2.481 0 0
HCMV Infection R-HSA-9609646 3.403549e-03 2.468 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.418336e-03 2.466 0 0
Signaling by EGFR in Cancer R-HSA-1643713 3.564773e-03 2.448 0 0
Defective pyroptosis R-HSA-9710421 3.568994e-03 2.447 0 0
IRE1alpha activates chaperones R-HSA-381070 3.682769e-03 2.434 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 4.001577e-03 2.398 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 4.001577e-03 2.398 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 4.172233e-03 2.380 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 4.172233e-03 2.380 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 4.955389e-03 2.305 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 4.572949e-03 2.340 0 0
mRNA 3'-end processing R-HSA-72187 4.898338e-03 2.310 0 0
snRNP Assembly R-HSA-191859 4.891643e-03 2.311 0 0
Metabolism of non-coding RNA R-HSA-194441 4.891643e-03 2.311 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.257108e-03 2.371 0 0
Intracellular signaling by second messengers R-HSA-9006925 4.522365e-03 2.345 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 4.572949e-03 2.340 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 4.418803e-03 2.355 0 0
Amyloid fiber formation R-HSA-977225 5.009844e-03 2.300 0 0
PKR-mediated signaling R-HSA-9833482 4.496881e-03 2.347 0 0
Interleukin-12 family signaling R-HSA-447115 4.767961e-03 2.322 0 0
Cilium Assembly R-HSA-5617833 5.178064e-03 2.286 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 5.338800e-03 2.273 0 0
Regulation of PTEN gene transcription R-HSA-8943724 5.539250e-03 2.257 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 5.735253e-03 2.241 0 0
Eukaryotic Translation Termination R-HSA-72764 6.043244e-03 2.219 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 6.359025e-03 2.197 0 0
Base Excision Repair R-HSA-73884 6.443325e-03 2.191 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 6.491684e-03 2.188 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 6.491684e-03 2.188 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 6.491684e-03 2.188 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 6.491684e-03 2.188 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 6.491684e-03 2.188 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 6.491684e-03 2.188 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 6.491684e-03 2.188 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 6.491684e-03 2.188 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 6.491684e-03 2.188 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 6.491684e-03 2.188 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 6.491684e-03 2.188 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 7.067036e-03 2.151 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 7.067036e-03 2.151 0 0
Maturation of protein E R-HSA-9694493 7.067036e-03 2.151 0 0
Maturation of protein E R-HSA-9683683 7.067036e-03 2.151 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 7.097830e-03 2.149 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 7.103208e-03 2.149 0 0
Signaling by NOTCH3 R-HSA-9012852 7.209057e-03 2.142 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 7.281105e-03 2.138 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 7.291054e-03 2.137 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 7.400087e-03 2.131 0 0
Deubiquitination R-HSA-5688426 7.507168e-03 2.125 0 0
Oncogenic MAPK signaling R-HSA-6802957 7.560863e-03 2.121 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 7.940153e-03 2.100 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 7.940153e-03 2.100 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 7.940153e-03 2.100 0 0
Regulation of CDH11 function R-HSA-9762292 7.940153e-03 2.100 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 7.870936e-03 2.104 0 0
Josephin domain DUBs R-HSA-5689877 7.940153e-03 2.100 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 7.940153e-03 2.100 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 8.146555e-03 2.089 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 7.904286e-03 2.102 0 0
Signaling by PTK6 R-HSA-8848021 7.904286e-03 2.102 0 0
Pexophagy R-HSA-9664873 7.940153e-03 2.100 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.453933e-03 2.073 0 0
Regulation of TP53 Degradation R-HSA-6804757 8.010666e-03 2.096 0 0
Interferon Signaling R-HSA-913531 9.225621e-03 2.035 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 9.480587e-03 2.023 0 0
Spry regulation of FGF signaling R-HSA-1295596 9.480587e-03 2.023 0 0
Glycolysis R-HSA-70171 9.516105e-03 2.022 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.067349e-02 1.972 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 1.067349e-02 1.972 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.080153e-02 1.967 0 0
Diseases of programmed cell death R-HSA-9645723 1.106632e-02 1.956 0 0
Myogenesis R-HSA-525793 1.128674e-02 1.947 0 0
Reproduction R-HSA-1474165 1.177030e-02 1.929 0 0
DNA Replication R-HSA-69306 1.177997e-02 1.929 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 1.193886e-02 1.923 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.206412e-02 1.919 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 1.206412e-02 1.919 0 0
DAG and IP3 signaling R-HSA-1489509 1.228038e-02 1.911 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.234356e-02 1.909 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.234356e-02 1.909 0 0
Signaling by ERBB2 R-HSA-1227986 1.289118e-02 1.890 0 0
RNA Polymerase II Transcription R-HSA-73857 1.301753e-02 1.885 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.328773e-02 1.877 0 0
Smooth Muscle Contraction R-HSA-445355 1.347033e-02 1.871 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.435671e-02 1.843 0 0
Telomere Maintenance R-HSA-157579 1.449129e-02 1.839 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.483457e-02 1.829 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.493993e-02 1.826 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.527661e-02 1.816 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.527661e-02 1.816 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.527661e-02 1.816 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.527661e-02 1.816 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.527661e-02 1.816 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.569425e-02 1.804 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.653408e-02 1.782 0 0
G alpha (12/13) signalling events R-HSA-416482 1.690102e-02 1.772 0 0
mTORC1-mediated signalling R-HSA-166208 1.717121e-02 1.765 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 1.717121e-02 1.765 0 0
Intraflagellar transport R-HSA-5620924 1.764678e-02 1.753 0 0
Developmental Cell Lineages R-HSA-9734767 1.786647e-02 1.748 0 0
IRAK1 recruits IKK complex R-HSA-937039 1.793272e-02 1.746 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 1.793272e-02 1.746 0 0
VLDLR internalisation and degradation R-HSA-8866427 1.793272e-02 1.746 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.824266e-02 1.739 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 1.825101e-02 1.739 0 0
Signaling by TGFB family members R-HSA-9006936 1.841160e-02 1.735 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.850955e-02 1.733 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.862817e-02 1.730 0 0
NRAGE signals death through JNK R-HSA-193648 1.876573e-02 1.727 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.912646e-02 1.718 0 0
Formation of annular gap junctions R-HSA-196025 2.036226e-02 1.691 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.254858e-02 1.647 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.199253e-02 1.658 0 0
Ephrin signaling R-HSA-3928664 2.199253e-02 1.658 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 2.113814e-02 1.675 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 2.433448e-02 1.614 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 2.433448e-02 1.614 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 2.400500e-02 1.620 0 0
Viral mRNA Translation R-HSA-192823 2.322584e-02 1.634 0 0
Ribosome-associated quality control R-HSA-9948299 2.173625e-02 1.663 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.977456e-02 1.704 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.433448e-02 1.614 0 0
MTOR signalling R-HSA-165159 2.060651e-02 1.686 0 0
Degradation of CDH1 R-HSA-9766229 1.977456e-02 1.704 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 2.036226e-02 1.691 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.377007e-02 1.624 0 0
Vesicle-mediated transport R-HSA-5653656 2.333460e-02 1.632 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 2.036226e-02 1.691 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.199253e-02 1.658 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.963924e-02 1.707 0 0
Signaling by Hedgehog R-HSA-5358351 2.173625e-02 1.663 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.199253e-02 1.658 0 0
Selenocysteine synthesis R-HSA-2408557 1.995784e-02 1.700 0 0
Viral Infection Pathways R-HSA-9824446 2.571669e-02 1.590 0 0
Modulation by Mtb of host immune system R-HSA-9637628 2.036226e-02 1.691 0 0
Translesion Synthesis by POLH R-HSA-110320 2.631883e-02 1.580 0 0
Gap junction degradation R-HSA-190873 2.685365e-02 1.571 0 0
Cellular response to starvation R-HSA-9711097 2.728651e-02 1.564 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 2.776741e-02 1.556 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 2.776741e-02 1.556 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 2.785462e-02 1.555 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 2.787144e-02 1.555 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.839249e-02 1.547 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.839249e-02 1.547 0 0
Signaling by NOTCH1 R-HSA-1980143 2.849996e-02 1.545 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 2.887042e-02 1.540 0 0
PLC beta mediated events R-HSA-112043 3.083981e-02 1.511 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 3.108426e-02 1.507 0 0
Nephrin family interactions R-HSA-373753 3.117521e-02 1.506 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.137675e-02 1.503 0 0
Muscle contraction R-HSA-397014 3.162949e-02 1.500 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 3.171208e-02 1.499 0 0
Nuclear RNA decay R-HSA-9930044 3.171208e-02 1.499 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.171208e-02 1.499 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 3.210883e-02 1.493 0 0
Manipulation of host energy metabolism R-HSA-9636667 3.234852e-02 1.490 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 3.234852e-02 1.490 0 0
Breakdown of the nuclear lamina R-HSA-352238 3.234852e-02 1.490 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 3.333065e-02 1.477 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 3.363541e-02 1.473 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 3.387055e-02 1.470 0 0
Translesion synthesis by REV1 R-HSA-110312 3.392991e-02 1.469 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.428543e-02 1.465 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.528879e-02 1.452 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 3.591926e-02 1.445 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.591926e-02 1.445 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 3.658137e-02 1.437 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 3.658137e-02 1.437 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.684928e-02 1.434 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 3.688181e-02 1.433 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 3.688181e-02 1.433 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 3.829777e-02 1.417 0 0
PKMTs methylate histone lysines R-HSA-3214841 3.829777e-02 1.417 0 0
PTEN Regulation R-HSA-6807070 3.891916e-02 1.410 0 0
Unfolded Protein Response (UPR) R-HSA-381119 3.891916e-02 1.410 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 3.963345e-02 1.402 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 3.963345e-02 1.402 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 4.046923e-02 1.393 0 0
MyD88-independent TLR4 cascade R-HSA-166166 4.046923e-02 1.393 0 0
Dual Incision in GG-NER R-HSA-5696400 4.048728e-02 1.393 0 0
Nuclear import of Rev protein R-HSA-180746 4.048728e-02 1.393 0 0
Translesion synthesis by POLI R-HSA-5656121 4.074547e-02 1.390 0 0
Negative regulation of FLT3 R-HSA-9706369 4.074547e-02 1.390 0 0
Generic Transcription Pathway R-HSA-212436 4.080200e-02 1.389 0 0
Glucose metabolism R-HSA-70326 4.151691e-02 1.382 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 4.255343e-02 1.371 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 4.255343e-02 1.371 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 4.255343e-02 1.371 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 4.261818e-02 1.370 0 0
SARS-CoV-2 Infection R-HSA-9694516 4.350483e-02 1.361 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 4.476671e-02 1.349 0 0
Oncogene Induced Senescence R-HSA-2559585 4.542597e-02 1.343 0 0
MITF-M-dependent gene expression R-HSA-9856651 4.634474e-02 1.334 0 0
Ca-dependent events R-HSA-111996 4.725450e-02 1.326 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 4.725450e-02 1.326 0 0
PIP3 activates AKT signaling R-HSA-1257604 4.745107e-02 1.324 0 0
Late endosomal microautophagy R-HSA-9615710 4.777293e-02 1.321 0 0
Translesion synthesis by POLK R-HSA-5655862 4.833246e-02 1.316 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 4.833246e-02 1.316 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 4.884606e-02 1.311 0 0
Notch-HLH transcription pathway R-HSA-350054 4.910379e-02 1.309 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.955721e-02 1.305 0 0
Neutrophil degranulation R-HSA-6798695 4.985612e-02 1.302 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 5.279081e-02 1.277 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 6.776854e-02 1.169 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 6.776854e-02 1.169 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 6.776854e-02 1.169 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 6.776854e-02 1.169 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 6.398087e-02 1.194 0 0
Repression of WNT target genes R-HSA-4641265 6.398087e-02 1.194 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 6.398087e-02 1.194 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 5.669810e-02 1.246 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 5.669810e-02 1.246 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 6.584279e-02 1.181 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 5.391082e-02 1.268 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 6.051963e-02 1.218 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.516415e-02 1.124 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 6.036947e-02 1.219 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 5.300513e-02 1.276 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 5.266579e-02 1.278 0 0
TGFBR3 expression R-HSA-9839394 7.229188e-02 1.141 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 6.312226e-02 1.200 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 6.397007e-02 1.194 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 7.229188e-02 1.141 0 0
Orc1 removal from chromatin R-HSA-68949 5.756765e-02 1.240 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 5.696808e-02 1.244 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 5.696808e-02 1.244 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 5.696808e-02 1.244 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 5.696808e-02 1.244 0 0
Interleukin-1 signaling R-HSA-9020702 6.387998e-02 1.195 0 0
DNA Repair R-HSA-73894 6.321740e-02 1.199 0 0
Calmodulin induced events R-HSA-111933 5.074371e-02 1.295 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.374662e-02 1.270 0 0
CaM pathway R-HSA-111997 5.074371e-02 1.295 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 5.844492e-02 1.233 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 5.131941e-02 1.290 0 0
G-protein mediated events R-HSA-112040 5.169087e-02 1.287 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 6.051963e-02 1.218 0 0
Signaling by TGFBR3 R-HSA-9839373 6.908031e-02 1.161 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 5.279081e-02 1.277 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 5.301867e-02 1.276 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 5.669810e-02 1.246 0 0
rRNA processing R-HSA-72312 7.492338e-02 1.125 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 5.696808e-02 1.244 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.516415e-02 1.124 0 0
Signaling by FGFR2 R-HSA-5654738 7.234711e-02 1.141 0 0
MAP kinase activation R-HSA-450294 6.177083e-02 1.209 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 7.537791e-02 1.123 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 6.776854e-02 1.169 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 6.908031e-02 1.161 0 0
Organelle biogenesis and maintenance R-HSA-1852241 5.934411e-02 1.227 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 6.398087e-02 1.194 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 6.398087e-02 1.194 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 5.756765e-02 1.240 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 5.131941e-02 1.290 0 0
FLT3 signaling in disease R-HSA-9682385 5.074371e-02 1.295 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 6.254250e-02 1.204 0 0
SARS-CoV Infections R-HSA-9679506 5.159080e-02 1.287 0 0
Activation of BH3-only proteins R-HSA-114452 5.391082e-02 1.268 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 7.541475e-02 1.123 0 0
Regulation of signaling by CBL R-HSA-912631 7.576031e-02 1.121 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 7.576031e-02 1.121 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 7.576031e-02 1.121 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 7.592050e-02 1.120 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 7.592050e-02 1.120 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 7.603219e-02 1.119 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 7.603219e-02 1.119 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 7.603219e-02 1.119 0 0
Response of endothelial cells to shear stress R-HSA-9860931 7.630313e-02 1.117 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 7.970529e-02 1.099 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 7.970529e-02 1.099 0 0
TNF signaling R-HSA-75893 8.009734e-02 1.096 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.077394e-02 1.093 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.077394e-02 1.093 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 8.117834e-02 1.091 0 0
NGF-stimulated transcription R-HSA-9031628 8.201649e-02 1.086 0 0
Striated Muscle Contraction R-HSA-390522 8.320109e-02 1.080 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 8.320109e-02 1.080 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 8.320637e-02 1.080 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 8.444308e-02 1.073 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 8.444308e-02 1.073 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 8.564978e-02 1.067 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 8.643828e-02 1.063 0 0
Deletions in the AXIN1 gene destabilize the destruction complex R-HSA-5467345 8.877637e-02 1.052 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 8.899633e-02 1.051 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 8.899633e-02 1.051 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 8.913544e-02 1.050 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 8.913544e-02 1.050 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 8.913544e-02 1.050 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 8.985352e-02 1.046 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 8.985352e-02 1.046 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 8.985352e-02 1.046 0 0
Interaction between L1 and Ankyrins R-HSA-445095 9.069989e-02 1.042 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 9.069989e-02 1.042 0 0
Mitophagy R-HSA-5205647 9.171147e-02 1.038 0 0
NOD1/2 Signaling Pathway R-HSA-168638 9.171147e-02 1.038 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.197462e-02 1.036 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 9.785859e-02 1.009 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 9.785859e-02 1.009 0 0
UCH proteinases R-HSA-5689603 9.807127e-02 1.008 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 9.935943e-02 1.003 0 0
EPH-Ephrin signaling R-HSA-2682334 1.000922e-01 1.000 0 0
Regulation of Apoptosis R-HSA-169911 1.006902e-01 0.997 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.007703e-01 0.997 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.007703e-01 0.997 0 0
S Phase R-HSA-69242 1.012116e-01 0.995 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 1.023719e-01 0.990 0 0
ARMS-mediated activation R-HSA-170984 1.026716e-01 0.989 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.026716e-01 0.989 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 1.026716e-01 0.989 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.026716e-01 0.989 0 0
Unwinding of DNA R-HSA-176974 1.026716e-01 0.989 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.032434e-01 0.986 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 1.032434e-01 0.986 0 0
Protein methylation R-HSA-8876725 1.032434e-01 0.986 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 1.032434e-01 0.986 0 0
TBC/RABGAPs R-HSA-8854214 1.074360e-01 0.969 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 1.074360e-01 0.969 0 0
Signaling by FGFR4 R-HSA-5654743 1.074360e-01 0.969 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.074360e-01 0.969 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 1.081794e-01 0.966 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 1.081794e-01 0.966 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 1.081794e-01 0.966 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.082827e-01 0.965 0 0
PCP/CE pathway R-HSA-4086400 1.109768e-01 0.955 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 1.114025e-01 0.953 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 1.114025e-01 0.953 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 1.119690e-01 0.951 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 1.162900e-01 0.934 0 0
Interleukin-17 signaling R-HSA-448424 1.167814e-01 0.933 0 0
Prolonged ERK activation events R-HSA-169893 1.183002e-01 0.927 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 1.183002e-01 0.927 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 1.183002e-01 0.927 0 0
Regulation of BACH1 activity R-HSA-9708530 1.183002e-01 0.927 0 0
Platelet degranulation R-HSA-114608 1.199369e-01 0.921 0 0
Degradation of AXIN R-HSA-4641257 1.200219e-01 0.921 0 0
Degradation of DVL R-HSA-4641258 1.200219e-01 0.921 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.200219e-01 0.921 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 1.225804e-01 0.912 0 0
Activation of the pre-replicative complex R-HSA-68962 1.225804e-01 0.912 0 0
tRNA processing in the nucleus R-HSA-6784531 1.227915e-01 0.911 0 0
FGFR2 alternative splicing R-HSA-6803529 1.228279e-01 0.911 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.228279e-01 0.911 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 1.228279e-01 0.911 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.254260e-01 0.902 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.255223e-01 0.901 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.255223e-01 0.901 0 0
Signaling by FGFR3 R-HSA-5654741 1.255223e-01 0.901 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 1.285792e-01 0.891 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.303543e-01 0.885 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 1.309282e-01 0.883 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.318855e-01 0.880 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.342434e-01 0.872 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 1.351247e-01 0.869 0 0
Regulation of TNFR1 signaling R-HSA-5357905 1.351247e-01 0.869 0 0
Regulation of pyruvate metabolism R-HSA-9861718 1.351247e-01 0.869 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.696763e-01 0.770 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 1.696763e-01 0.770 0 0
PI and PC transport between ER and Golgi membranes R-HSA-1483196 2.433981e-01 0.614 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 2.433981e-01 0.614 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5660724 2.433981e-01 0.614 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.433981e-01 0.614 0 0
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420 2.433981e-01 0.614 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.433981e-01 0.614 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.433981e-01 0.614 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.433981e-01 0.614 0 0
MyD88 deficiency (TLR5) R-HSA-5602680 2.433981e-01 0.614 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5619081 2.433981e-01 0.614 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 1.388527e-01 0.857 0 0
IRS activation R-HSA-74713 1.388527e-01 0.857 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.388527e-01 0.857 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.711108e-01 0.767 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 1.711108e-01 0.767 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 1.711108e-01 0.767 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.044312e-01 0.689 0 0
PECAM1 interactions R-HSA-210990 1.431623e-01 0.844 0 0
SOS-mediated signalling R-HSA-112412 2.383714e-01 0.623 0 0
DAG1 core M1 glycosylations R-HSA-8932506 2.383714e-01 0.623 0 0
Type I hemidesmosome assembly R-HSA-446107 2.725590e-01 0.565 0 0
DAG1 core M2 glycosylations R-HSA-8932504 2.725590e-01 0.565 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 2.725590e-01 0.565 0 0
Formation of axial mesoderm R-HSA-9796292 2.115291e-01 0.675 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 2.115291e-01 0.675 0 0
GAB1 signalosome R-HSA-180292 1.685121e-01 0.773 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.504275e-01 0.823 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.054630e-01 0.687 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.603402e-01 0.584 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.444817e-01 0.612 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.444817e-01 0.612 0 0
Termination of translesion DNA synthesis R-HSA-5656169 2.288746e-01 0.640 0 0
RET signaling R-HSA-8853659 2.142622e-01 0.669 0 0
Trafficking of AMPA receptors R-HSA-399719 2.630944e-01 0.580 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.998899e-01 0.699 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 2.117498e-01 0.674 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 2.405134e-01 0.619 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 2.542958e-01 0.595 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.362415e-01 0.627 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 2.488385e-01 0.604 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 2.488385e-01 0.604 0 0
Nucleotide Excision Repair R-HSA-5696398 1.363428e-01 0.865 0 0
RAF activation R-HSA-5673000 1.859245e-01 0.731 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 1.859245e-01 0.731 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 2.369483e-01 0.625 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 2.369483e-01 0.625 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 1.650971e-01 0.782 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 1.803585e-01 0.744 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 1.954013e-01 0.709 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 2.603402e-01 0.584 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 2.369483e-01 0.625 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 1.510047e-01 0.821 0 0
Diseases of mitotic cell cycle R-HSA-9675126 1.464971e-01 0.834 0 0
Regulation of RAS by GAPs R-HSA-5658442 1.770247e-01 0.752 0 0
Degradation of CRY and PER proteins R-HSA-9932298 1.758036e-01 0.755 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.137208e-01 0.670 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 2.238727e-01 0.650 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 1.638560e-01 0.786 0 0
Cyclin D associated events in G1 R-HSA-69231 2.137208e-01 0.670 0 0
G1 Phase R-HSA-69236 2.137208e-01 0.670 0 0
Switching of origins to a post-replicative state R-HSA-69052 1.398171e-01 0.854 0 0
Late Phase of HIV Life Cycle R-HSA-162599 2.396901e-01 0.620 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 1.711108e-01 0.767 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 1.638560e-01 0.786 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 1.638560e-01 0.786 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 1.450876e-01 0.838 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 1.999076e-01 0.699 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 1.999076e-01 0.699 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 1.999076e-01 0.699 0 0
Signaling by NOTCH4 R-HSA-9013694 1.479960e-01 0.830 0 0
Ion homeostasis R-HSA-5578775 1.471975e-01 0.832 0 0
Platelet calcium homeostasis R-HSA-418360 2.288746e-01 0.640 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 2.669928e-01 0.574 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.490912e-01 0.827 0 0
Toll-like Receptor Cascades R-HSA-168898 1.803372e-01 0.744 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 1.758036e-01 0.755 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 1.758036e-01 0.755 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 1.954013e-01 0.709 0 0
HIV Life Cycle R-HSA-162587 2.059012e-01 0.686 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.822619e-01 0.739 0 0
Signaling by NOTCH2 R-HSA-1980145 1.859245e-01 0.731 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.822619e-01 0.739 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 2.048922e-01 0.688 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.638449e-01 0.786 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 1.723429e-01 0.764 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.758036e-01 0.755 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 2.007568e-01 0.697 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 2.048922e-01 0.688 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 1.717891e-01 0.765 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 1.685121e-01 0.773 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.338599e-01 0.631 0 0
HDMs demethylate histones R-HSA-3214842 1.651221e-01 0.782 0 0
Regulated Necrosis R-HSA-5218859 1.757105e-01 0.755 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 1.857090e-01 0.731 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.019434e-01 0.695 0 0
Translation R-HSA-72766 1.855874e-01 0.731 0 0
Inhibition of Host mRNA Processing and RNA Silencing R-HSA-168315 2.433981e-01 0.614 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 2.433981e-01 0.614 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 1.388527e-01 0.857 0 0
Proton/oligopeptide cotransporters R-HSA-427975 1.711108e-01 0.767 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 2.115291e-01 0.675 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 2.603402e-01 0.584 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 2.603402e-01 0.584 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 1.522869e-01 0.817 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.444817e-01 0.612 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 1.859245e-01 0.731 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 1.859245e-01 0.731 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 2.142622e-01 0.669 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 2.289573e-01 0.640 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 2.269806e-01 0.644 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.979756e-01 0.703 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 2.089294e-01 0.680 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.567137e-01 0.805 0 0
Interleukin-1 family signaling R-HSA-446652 2.406322e-01 0.619 0 0
Formation of the cornified envelope R-HSA-6809371 2.206649e-01 0.656 0 0
MAPK family signaling cascades R-HSA-5683057 1.744912e-01 0.758 0 0
HCMV Late Events R-HSA-9610379 2.059012e-01 0.686 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 1.591913e-01 0.798 0 0
Frs2-mediated activation R-HSA-170968 2.115291e-01 0.675 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 1.638560e-01 0.786 0 0
G1/S Transition R-HSA-69206 2.369483e-01 0.625 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 2.603402e-01 0.584 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 2.269806e-01 0.644 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 2.269806e-01 0.644 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 2.160022e-01 0.666 0 0
Rap1 signalling R-HSA-392517 1.866904e-01 0.729 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 2.592417e-01 0.586 0 0
DCC mediated attractive signaling R-HSA-418885 2.603402e-01 0.584 0 0
Signaling by MET R-HSA-6806834 2.019434e-01 0.695 0 0
TCR signaling R-HSA-202403 1.711419e-01 0.767 0 0
Disorders of Nervous System Development R-HSA-9697154 1.879395e-01 0.726 0 0
Pervasive developmental disorders R-HSA-9005895 1.879395e-01 0.726 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.879395e-01 0.726 0 0
Vpu mediated degradation of CD4 R-HSA-180534 1.723429e-01 0.764 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 1.859245e-01 0.731 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 1.859245e-01 0.731 0 0
Signaling by FGFR1 R-HSA-5654736 1.471975e-01 0.832 0 0
Signaling by FGFR R-HSA-190236 1.446921e-01 0.840 0 0
Signaling by ERBB4 R-HSA-1236394 2.374310e-01 0.624 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 2.383714e-01 0.623 0 0
STING mediated induction of host immune responses R-HSA-1834941 1.866904e-01 0.729 0 0
Semaphorin interactions R-HSA-373755 2.201210e-01 0.657 0 0
Adaptive Immune System R-HSA-1280218 1.929185e-01 0.715 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 2.182024e-01 0.661 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 2.491590e-01 0.604 0 0
SLC-mediated transport of oligopeptides R-HSA-9959399 2.383714e-01 0.623 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.879395e-01 0.726 0 0
Physiological factors R-HSA-5578768 2.357116e-01 0.628 0 0
Stabilization of p53 R-HSA-69541 1.411143e-01 0.850 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 2.630944e-01 0.580 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 2.269806e-01 0.644 0 0
Signaling by NTRKs R-HSA-166520 2.112931e-01 0.675 0 0
Pyruvate metabolism R-HSA-70268 1.891406e-01 0.723 0 0
Cellular response to chemical stress R-HSA-9711123 2.291096e-01 0.640 0 0
Formation of definitive endoderm R-HSA-9823730 2.054630e-01 0.687 0 0
Protein hydroxylation R-HSA-9629569 2.054630e-01 0.687 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 2.044312e-01 0.689 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 2.725590e-01 0.565 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.567841e-01 0.805 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.750077e-01 0.757 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 2.315371e-01 0.635 0 0
Hedgehog 'on' state R-HSA-5632684 2.055929e-01 0.687 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 2.383714e-01 0.623 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 2.383714e-01 0.623 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 2.383714e-01 0.623 0 0
Adrenoceptors R-HSA-390696 2.725590e-01 0.565 0 0
Assembly Of The HIV Virion R-HSA-175474 2.444817e-01 0.612 0 0
Gluconeogenesis R-HSA-70263 2.683039e-01 0.571 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 1.803585e-01 0.744 0 0
Neurodegenerative Diseases R-HSA-8863678 1.504275e-01 0.823 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.504275e-01 0.823 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.363164e-01 0.865 0 0
Plasma lipoprotein clearance R-HSA-8964043 2.592417e-01 0.586 0 0
Host Interactions of HIV factors R-HSA-162909 2.206649e-01 0.656 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.683039e-01 0.571 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.706853e-01 0.768 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.960931e-01 0.708 0 0
Toxicity of botulinum toxin type C (botC) R-HSA-5250971 1.388527e-01 0.857 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 2.383714e-01 0.623 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 2.725590e-01 0.565 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.685121e-01 0.773 0 0
Selenoamino acid metabolism R-HSA-2408522 1.877929e-01 0.726 0 0
Suppression of phagosomal maturation R-HSA-9637687 1.803585e-01 0.744 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.364544e-01 0.865 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.444817e-01 0.612 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 2.725590e-01 0.565 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.488385e-01 0.604 0 0
FLT3 Signaling R-HSA-9607240 1.638560e-01 0.786 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 2.444817e-01 0.612 0 0
Glycogen storage diseases R-HSA-3229121 1.510047e-01 0.821 0 0
Glycogen synthesis R-HSA-3322077 2.054630e-01 0.687 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.488385e-01 0.604 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 2.736740e-01 0.563 0 0
Dual incision in TC-NER R-HSA-6782135 2.746444e-01 0.561 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 2.747662e-01 0.561 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 2.747662e-01 0.561 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 2.747662e-01 0.561 0 0
Opioid Signalling R-HSA-111885 2.775006e-01 0.557 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 2.791655e-01 0.554 0 0
DNA Damage Bypass R-HSA-73893 2.825136e-01 0.549 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 2.852765e-01 0.545 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 2.852765e-01 0.545 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.852765e-01 0.545 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 2.852765e-01 0.545 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 2.878161e-01 0.541 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 2.905021e-01 0.537 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.905021e-01 0.537 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 2.905021e-01 0.537 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.968313e-01 0.527 0 0
FGFR1 mutant receptor activation R-HSA-1839124 2.983760e-01 0.525 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 2.983760e-01 0.525 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 3.055549e-01 0.515 0 0
Deadenylation of mRNA R-HSA-429947 3.055549e-01 0.515 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 3.055549e-01 0.515 0 0
Circadian clock R-HSA-9909396 3.064321e-01 0.514 0 0
Lipophagy R-HSA-9613354 3.066828e-01 0.513 0 0
ALK mutants bind TKIs R-HSA-9700645 3.066828e-01 0.513 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.066828e-01 0.513 0 0
GP1b-IX-V activation signalling R-HSA-430116 3.066828e-01 0.513 0 0
Cellular response to mitochondrial stress R-HSA-9840373 3.066828e-01 0.513 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.066828e-01 0.513 0 0
Regulated proteolysis of p75NTR R-HSA-193692 3.066828e-01 0.513 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.066828e-01 0.513 0 0
Interleukin-1 processing R-HSA-448706 3.066828e-01 0.513 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 3.066828e-01 0.513 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.066828e-01 0.513 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.103917e-01 0.508 0 0
Disorders of Developmental Biology R-HSA-9675151 3.103917e-01 0.508 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 3.105785e-01 0.508 0 0
Defective SLC12A1 causes Bartter syndrome 1 (BS1) R-HSA-5619104 3.105785e-01 0.508 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 3.105785e-01 0.508 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 3.105785e-01 0.508 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 3.105785e-01 0.508 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 3.105785e-01 0.508 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 3.105785e-01 0.508 0 0
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177 3.105785e-01 0.508 0 0
Interleukin-33 signaling R-HSA-9014843 3.105785e-01 0.508 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 3.105785e-01 0.508 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 3.105785e-01 0.508 0 0
Neurophilin interactions with VEGF and VEGFR R-HSA-194306 3.105785e-01 0.508 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 3.114412e-01 0.507 0 0
Hedgehog ligand biogenesis R-HSA-5358346 3.114412e-01 0.507 0 0
Transmission across Chemical Synapses R-HSA-112315 3.120574e-01 0.506 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 3.165353e-01 0.500 0 0
Regulation of mitotic cell cycle R-HSA-453276 3.165353e-01 0.500 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 3.224783e-01 0.491 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.224783e-01 0.491 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 3.261105e-01 0.487 0 0
Long-term potentiation R-HSA-9620244 3.263009e-01 0.486 0 0
Tight junction interactions R-HSA-420029 3.263009e-01 0.486 0 0
Sema4D in semaphorin signaling R-HSA-400685 3.263009e-01 0.486 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 3.355666e-01 0.474 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 3.355666e-01 0.474 0 0
Rab regulation of trafficking R-HSA-9007101 3.370575e-01 0.472 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.404849e-01 0.468 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.404849e-01 0.468 0 0
PI3K/AKT activation R-HSA-198203 3.404849e-01 0.468 0 0
Signal attenuation R-HSA-74749 3.404849e-01 0.468 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 3.404849e-01 0.468 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 3.404849e-01 0.468 0 0
Signaling by Leptin R-HSA-2586552 3.404849e-01 0.468 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 3.408847e-01 0.467 0 0
Regulation of PTEN stability and activity R-HSA-8948751 3.408847e-01 0.467 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 3.408847e-01 0.467 0 0
Ca2+ pathway R-HSA-4086398 3.420053e-01 0.466 0 0
Metalloprotease DUBs R-HSA-5689901 3.471278e-01 0.460 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 3.548613e-01 0.450 0 0
Signaling by FGFR in disease R-HSA-1226099 3.548613e-01 0.450 0 0
RMTs methylate histone arginines R-HSA-3214858 3.549146e-01 0.450 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 3.593112e-01 0.445 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 3.606921e-01 0.443 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 3.677776e-01 0.434 0 0
Iron uptake and transport R-HSA-917937 3.677776e-01 0.434 0 0
Cristae formation R-HSA-8949613 3.679728e-01 0.434 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 3.679728e-01 0.434 0 0
Cellular response to hypoxia R-HSA-1234174 3.694181e-01 0.432 0 0
Inositol phosphate metabolism R-HSA-1483249 3.699632e-01 0.432 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 3.712278e-01 0.430 0 0
PLC-gamma1 signalling R-HSA-167021 3.717973e-01 0.430 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 3.717973e-01 0.430 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 3.717973e-01 0.430 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 3.717973e-01 0.430 0 0
MET activates PTPN11 R-HSA-8865999 3.717973e-01 0.430 0 0
MET interacts with TNS proteins R-HSA-8875513 3.717973e-01 0.430 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 3.717973e-01 0.430 0 0
Histamine receptors R-HSA-390650 3.717973e-01 0.430 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 3.717973e-01 0.430 0 0
Bicarbonate transporters R-HSA-425381 3.737535e-01 0.427 0 0
LGI-ADAM interactions R-HSA-5682910 3.737535e-01 0.427 0 0
ChREBP activates metabolic gene expression R-HSA-163765 3.737535e-01 0.427 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 3.856691e-01 0.414 0 0
Other interleukin signaling R-HSA-449836 3.856691e-01 0.414 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 3.875646e-01 0.412 0 0
Potential therapeutics for SARS R-HSA-9679191 3.959914e-01 0.402 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.063169e-01 0.391 0 0
Signaling by AXIN mutants R-HSA-4839735 4.063169e-01 0.391 0 0
Signaling by GSK3beta mutants R-HSA-5339716 4.063169e-01 0.391 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.063169e-01 0.391 0 0
Activation of RAC1 R-HSA-428540 4.063169e-01 0.391 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 4.069906e-01 0.390 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 4.069906e-01 0.390 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 4.094834e-01 0.388 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 4.094834e-01 0.388 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 4.104087e-01 0.387 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 4.104087e-01 0.387 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 4.104087e-01 0.387 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 4.104087e-01 0.387 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 4.104087e-01 0.387 0 0
Signal transduction by L1 R-HSA-445144 4.104087e-01 0.387 0 0
Signaling by Interleukins R-HSA-449147 4.169241e-01 0.380 0 0
Sensory processing of sound R-HSA-9659379 4.197493e-01 0.377 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.250627e-01 0.372 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 4.250627e-01 0.372 0 0
Signaling by ALK R-HSA-201556 4.250627e-01 0.372 0 0
ER-Phagosome pathway R-HSA-1236974 4.271884e-01 0.369 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 4.275834e-01 0.369 0 0
HCN channels R-HSA-1296061 4.275834e-01 0.369 0 0
ATP sensitive Potassium channels R-HSA-1296025 4.275834e-01 0.369 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 4.275834e-01 0.369 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 4.275834e-01 0.369 0 0
Signaling by MAP2K mutants R-HSA-9652169 4.275834e-01 0.369 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 4.275834e-01 0.369 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 4.275834e-01 0.369 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 4.275834e-01 0.369 0 0
Regulation of gap junction activity R-HSA-191650 4.275834e-01 0.369 0 0
GABA synthesis R-HSA-888568 4.275834e-01 0.369 0 0
TNFR1-mediated ceramide production R-HSA-5626978 4.275834e-01 0.369 0 0
NADE modulates death signalling R-HSA-205025 4.275834e-01 0.369 0 0
Synthesis of DNA R-HSA-69239 4.282476e-01 0.368 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 4.300420e-01 0.366 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 4.300420e-01 0.366 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 4.300420e-01 0.366 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 4.348312e-01 0.362 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 4.348312e-01 0.362 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 4.348312e-01 0.362 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.380383e-01 0.358 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 4.380383e-01 0.358 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 4.380383e-01 0.358 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 4.380383e-01 0.358 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 4.380383e-01 0.358 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 4.380383e-01 0.358 0 0
OAS antiviral response R-HSA-8983711 4.380383e-01 0.358 0 0
Downstream TCR signaling R-HSA-202424 4.394580e-01 0.357 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 4.430275e-01 0.354 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 4.430275e-01 0.354 0 0
Diseases of Immune System R-HSA-5260271 4.430275e-01 0.354 0 0
Glycogen metabolism R-HSA-8982491 4.430275e-01 0.354 0 0
Budding and maturation of HIV virion R-HSA-162588 4.504046e-01 0.346 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 4.588665e-01 0.338 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 4.601135e-01 0.337 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 4.632256e-01 0.334 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 4.662925e-01 0.331 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 4.688105e-01 0.329 0 0
Signaling by WNT in cancer R-HSA-4791275 4.705276e-01 0.327 0 0
DNA strand elongation R-HSA-69190 4.705276e-01 0.327 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 4.784185e-01 0.320 0 0
G2 Phase R-HSA-68911 4.784185e-01 0.320 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 4.784185e-01 0.320 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 4.784185e-01 0.320 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 4.784185e-01 0.320 0 0
Reelin signalling pathway R-HSA-8866376 4.784185e-01 0.320 0 0
Suppression of autophagy R-HSA-9636569 4.784185e-01 0.320 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 4.784185e-01 0.320 0 0
Muscarinic acetylcholine receptors R-HSA-390648 4.784185e-01 0.320 0 0
Pyrophosphate hydrolysis R-HSA-71737 4.784185e-01 0.320 0 0
Interleukin-36 pathway R-HSA-9014826 4.784185e-01 0.320 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 4.785074e-01 0.320 0 0
HIV Transcription Initiation R-HSA-167161 4.785074e-01 0.320 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 4.785074e-01 0.320 0 0
Translation of Structural Proteins R-HSA-9683701 4.785074e-01 0.320 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 4.797869e-01 0.319 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 4.824532e-01 0.317 0 0
Neuronal System R-HSA-112316 4.881334e-01 0.311 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 4.903713e-01 0.309 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 4.903713e-01 0.309 0 0
Cardiogenesis R-HSA-9733709 4.903713e-01 0.309 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 4.903713e-01 0.309 0 0
Protein-protein interactions at synapses R-HSA-6794362 4.970852e-01 0.304 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 4.985519e-01 0.302 0 0
Signaling by FGFR4 in disease R-HSA-5655291 4.985519e-01 0.302 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 4.985519e-01 0.302 0 0
Zinc transporters R-HSA-435354 4.985519e-01 0.302 0 0
Adipogenesis R-HSA-9843745 5.000706e-01 0.301 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 5.002202e-01 0.301 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 5.055385e-01 0.296 0 0
Syndecan interactions R-HSA-3000170 5.055385e-01 0.296 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.079592e-01 0.294 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 5.097366e-01 0.293 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 5.131963e-01 0.290 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 5.141132e-01 0.289 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 5.247419e-01 0.280 0 0
PDE3B signalling R-HSA-165160 5.247419e-01 0.280 0 0
PKB-mediated events R-HSA-109703 5.247419e-01 0.280 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 5.247419e-01 0.280 0 0
Loss-of-function mutations in DBT cause MSUD2 R-HSA-9865113 5.247419e-01 0.280 0 0
Loss-of-function mutations in DLD cause MSUD3/DLDD R-HSA-9907570 5.247419e-01 0.280 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 5.247419e-01 0.280 0 0
Signaling by MST1 R-HSA-8852405 5.247419e-01 0.280 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 5.247419e-01 0.280 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 5.247419e-01 0.280 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 5.247419e-01 0.280 0 0
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399 5.247419e-01 0.280 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.247419e-01 0.280 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 5.247419e-01 0.280 0 0
VEGF ligand-receptor interactions R-HSA-194313 5.247419e-01 0.280 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 5.247419e-01 0.280 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 5.247419e-01 0.280 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 5.247419e-01 0.280 0 0
HIV Infection R-HSA-162906 5.252101e-01 0.280 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.272029e-01 0.278 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 5.272029e-01 0.278 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 5.280772e-01 0.277 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 5.290815e-01 0.276 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 5.290815e-01 0.276 0 0
Calnexin/calreticulin cycle R-HSA-901042 5.290815e-01 0.276 0 0
Interferon alpha/beta signaling R-HSA-909733 5.379858e-01 0.269 0 0
ABC transporter disorders R-HSA-5619084 5.467004e-01 0.262 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 5.468943e-01 0.262 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 5.468943e-01 0.262 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 5.478874e-01 0.261 0 0
Signalling to ERKs R-HSA-187687 5.478874e-01 0.261 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 5.500315e-01 0.260 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 5.500315e-01 0.260 0 0
Formation of the nephric duct R-HSA-9830364 5.500315e-01 0.260 0 0
Interleukin-7 signaling R-HSA-1266695 5.500315e-01 0.260 0 0
Platelet activation, signaling and aggregation R-HSA-76002 5.517207e-01 0.258 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.547227e-01 0.256 0 0
Killing mechanisms R-HSA-9664420 5.547227e-01 0.256 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 5.547227e-01 0.256 0 0
Attachment and Entry R-HSA-9678110 5.547227e-01 0.256 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 5.547227e-01 0.256 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 5.547227e-01 0.256 0 0
Serotonin and melatonin biosynthesis R-HSA-209931 5.547227e-01 0.256 0 0
Signaling by LTK in cancer R-HSA-9842640 5.669536e-01 0.246 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 5.669536e-01 0.246 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.669536e-01 0.246 0 0
Autointegration results in viral DNA circles R-HSA-177539 5.669536e-01 0.246 0 0
Branched-chain ketoacid dehydrogenase kinase deficiency R-HSA-9912481 5.669536e-01 0.246 0 0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD R-HSA-9865125 5.669536e-01 0.246 0 0
H139Hfs13* PPM1K causes a mild variant of MSUD R-HSA-9912529 5.669536e-01 0.246 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 5.669536e-01 0.246 0 0
CREB phosphorylation R-HSA-199920 5.669536e-01 0.246 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 5.669536e-01 0.246 0 0
Abacavir transmembrane transport R-HSA-2161517 5.669536e-01 0.246 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 5.669536e-01 0.246 0 0
Nef and signal transduction R-HSA-164944 5.669536e-01 0.246 0 0
Neurofascin interactions R-HSA-447043 5.669536e-01 0.246 0 0
FOXO-mediated transcription R-HSA-9614085 5.705256e-01 0.244 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 5.713706e-01 0.243 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 5.713706e-01 0.243 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 5.713706e-01 0.243 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 5.713706e-01 0.243 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 5.762176e-01 0.239 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 5.794358e-01 0.237 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 5.810862e-01 0.236 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 5.810862e-01 0.236 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 5.810862e-01 0.236 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.810862e-01 0.236 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 5.810862e-01 0.236 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 5.810862e-01 0.236 0 0
Coenzyme A biosynthesis R-HSA-196783 5.810862e-01 0.236 0 0
Passive transport by Aquaporins R-HSA-432047 5.810862e-01 0.236 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 5.810862e-01 0.236 0 0
Infectious disease R-HSA-5663205 5.839737e-01 0.234 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 5.920698e-01 0.228 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 5.920698e-01 0.228 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 5.930281e-01 0.227 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 5.955436e-01 0.225 0 0
Hemostasis R-HSA-109582 6.027657e-01 0.220 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 6.054184e-01 0.218 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 6.054184e-01 0.218 0 0
Disinhibition of SNARE formation R-HSA-114516 6.054184e-01 0.218 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 6.054184e-01 0.218 0 0
PTK6 Expression R-HSA-8849473 6.054184e-01 0.218 0 0
Cysteine formation from homocysteine R-HSA-1614603 6.054184e-01 0.218 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 6.054184e-01 0.218 0 0
VLDL clearance R-HSA-8964046 6.054184e-01 0.218 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 6.054184e-01 0.218 0 0
CHL1 interactions R-HSA-447041 6.054184e-01 0.218 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 6.062816e-01 0.217 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 6.062816e-01 0.217 0 0
Specification of primordial germ cells R-HSA-9827857 6.062816e-01 0.217 0 0
Uptake and function of anthrax toxins R-HSA-5210891 6.062816e-01 0.217 0 0
Cardiac conduction R-HSA-5576891 6.086693e-01 0.216 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 6.106876e-01 0.214 0 0
Telomere Extension By Telomerase R-HSA-171319 6.121101e-01 0.213 0 0
Pyroptosis R-HSA-5620971 6.121101e-01 0.213 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 6.121101e-01 0.213 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 6.121101e-01 0.213 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 6.189085e-01 0.208 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 6.189085e-01 0.208 0 0
RAS processing R-HSA-9648002 6.189085e-01 0.208 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 6.303086e-01 0.200 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 6.303086e-01 0.200 0 0
PKA activation R-HSA-163615 6.303086e-01 0.200 0 0
Platelet sensitization by LDL R-HSA-432142 6.303086e-01 0.200 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 6.303086e-01 0.200 0 0
Presynaptic function of Kainate receptors R-HSA-500657 6.303086e-01 0.200 0 0
PKA activation in glucagon signalling R-HSA-164378 6.303086e-01 0.200 0 0
Signaling by Erythropoietin R-HSA-9006335 6.314779e-01 0.200 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 6.314779e-01 0.200 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 6.314779e-01 0.200 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 6.325228e-01 0.199 0 0
Generation of second messenger molecules R-HSA-202433 6.355290e-01 0.197 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 6.355290e-01 0.197 0 0
phospho-PLA2 pathway R-HSA-111995 6.404687e-01 0.194 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 6.404687e-01 0.194 0 0
MET receptor recycling R-HSA-8875656 6.404687e-01 0.194 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 6.404687e-01 0.194 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 6.404687e-01 0.194 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 6.404687e-01 0.194 0 0
FGFR1b ligand binding and activation R-HSA-190370 6.404687e-01 0.194 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 6.404687e-01 0.194 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 6.404687e-01 0.194 0 0
TGFBR3 PTM regulation R-HSA-9839383 6.404687e-01 0.194 0 0
Sodium/Proton exchangers R-HSA-425986 6.404687e-01 0.194 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 6.501641e-01 0.187 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 6.531757e-01 0.185 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 6.531757e-01 0.185 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.531757e-01 0.185 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.531757e-01 0.185 0 0
Specification of the neural plate border R-HSA-9834899 6.531757e-01 0.185 0 0
The NLRP3 inflammasome R-HSA-844456 6.531757e-01 0.185 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.531757e-01 0.185 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 6.531757e-01 0.185 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 6.549311e-01 0.184 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 6.549311e-01 0.184 0 0
Neurexins and neuroligins R-HSA-6794361 6.549311e-01 0.184 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.566717e-01 0.183 0 0
Integration of energy metabolism R-HSA-163685 6.641907e-01 0.178 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 6.664775e-01 0.176 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 6.673302e-01 0.176 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 6.689410e-01 0.175 0 0
WNT mediated activation of DVL R-HSA-201688 6.724074e-01 0.172 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 6.724074e-01 0.172 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 6.724074e-01 0.172 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 6.724074e-01 0.172 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.724074e-01 0.172 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 6.724074e-01 0.172 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 6.724074e-01 0.172 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 6.724074e-01 0.172 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 6.724074e-01 0.172 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 6.748996e-01 0.171 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 6.748996e-01 0.171 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 6.748996e-01 0.171 0 0
Translation of Structural Proteins R-HSA-9694635 6.751330e-01 0.171 0 0
Antigen processing-Cross presentation R-HSA-1236975 6.769936e-01 0.169 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 6.797734e-01 0.168 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 6.824989e-01 0.166 0 0
Regulation of insulin secretion R-HSA-422356 6.827580e-01 0.166 0 0
Immune System R-HSA-168256 6.851931e-01 0.164 0 0
G0 and Early G1 R-HSA-1538133 6.854767e-01 0.164 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 6.854767e-01 0.164 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 6.854767e-01 0.164 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 6.955028e-01 0.158 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 6.955028e-01 0.158 0 0
Early Phase of HIV Life Cycle R-HSA-162594 6.955028e-01 0.158 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 6.955028e-01 0.158 0 0
MAPK3 (ERK1) activation R-HSA-110056 7.015105e-01 0.154 0 0
Binding and entry of HIV virion R-HSA-173107 7.015105e-01 0.154 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 7.015105e-01 0.154 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 7.015105e-01 0.154 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 7.015105e-01 0.154 0 0
2-LTR circle formation R-HSA-164843 7.015105e-01 0.154 0 0
Receptor Mediated Mitophagy R-HSA-8934903 7.015105e-01 0.154 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 7.015105e-01 0.154 0 0
Integrin signaling R-HSA-354192 7.021046e-01 0.154 0 0
G-protein beta:gamma signalling R-HSA-397795 7.021046e-01 0.154 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 7.021046e-01 0.154 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 7.021046e-01 0.154 0 0
ABC-family proteins mediated transport R-HSA-382556 7.027770e-01 0.153 0 0
Transcription of the HIV genome R-HSA-167172 7.081619e-01 0.150 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 7.086825e-01 0.150 0 0
Netrin-1 signaling R-HSA-373752 7.113584e-01 0.148 0 0
Amine ligand-binding receptors R-HSA-375280 7.113584e-01 0.148 0 0
Attachment and Entry R-HSA-9694614 7.150128e-01 0.146 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 7.150128e-01 0.146 0 0
Ribavirin ADME R-HSA-9755088 7.150128e-01 0.146 0 0
Serine metabolism R-HSA-977347 7.150128e-01 0.146 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 7.150128e-01 0.146 0 0
Resolution of D-Loop Structures R-HSA-5693537 7.180533e-01 0.144 0 0
Effects of PIP2 hydrolysis R-HSA-114508 7.180533e-01 0.144 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 7.180533e-01 0.144 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 7.180533e-01 0.144 0 0
Protein localization R-HSA-9609507 7.182965e-01 0.144 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 7.280298e-01 0.138 0 0
DAG1 core M3 glycosylations R-HSA-8932505 7.280298e-01 0.138 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 7.280298e-01 0.138 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 7.280298e-01 0.138 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 7.280298e-01 0.138 0 0
vRNA Synthesis R-HSA-192814 7.280298e-01 0.138 0 0
Signaling by APC mutants R-HSA-4839744 7.280298e-01 0.138 0 0
vRNP Assembly R-HSA-192905 7.280298e-01 0.138 0 0
Propionyl-CoA catabolism R-HSA-71032 7.280298e-01 0.138 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 7.280298e-01 0.138 0 0
Vitamin B1 (thiamin) metabolism R-HSA-196819 7.280298e-01 0.138 0 0
Suppression of apoptosis R-HSA-9635465 7.280298e-01 0.138 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.280298e-01 0.138 0 0
Dissolution of Fibrin Clot R-HSA-75205 7.280298e-01 0.138 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 7.303221e-01 0.136 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 7.303221e-01 0.136 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 7.333307e-01 0.135 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 7.333307e-01 0.135 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 7.334614e-01 0.135 0 0
LDL clearance R-HSA-8964038 7.334614e-01 0.135 0 0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy R-HSA-9857377 7.334614e-01 0.135 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 7.334614e-01 0.135 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 7.334614e-01 0.135 0 0
Diseases of DNA repair R-HSA-9675135 7.382508e-01 0.132 0 0
Peroxisomal protein import R-HSA-9033241 7.449515e-01 0.128 0 0
Transferrin endocytosis and recycling R-HSA-917977 7.479472e-01 0.126 0 0
PERK regulates gene expression R-HSA-381042 7.479472e-01 0.126 0 0
RSV-host interactions R-HSA-9833110 7.492000e-01 0.125 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 7.508831e-01 0.124 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.508831e-01 0.124 0 0
Growth hormone receptor signaling R-HSA-982772 7.508831e-01 0.124 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 7.521944e-01 0.124 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 7.521944e-01 0.124 0 0
Integration of provirus R-HSA-162592 7.521944e-01 0.124 0 0
Signaling by AMER1 mutants R-HSA-4839748 7.521944e-01 0.124 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 7.521944e-01 0.124 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 7.521944e-01 0.124 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 7.521944e-01 0.124 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 7.521944e-01 0.124 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 7.521944e-01 0.124 0 0
Proton-coupled monocarboxylate transport R-HSA-433692 7.521944e-01 0.124 0 0
RAB geranylgeranylation R-HSA-8873719 7.562714e-01 0.121 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 7.562714e-01 0.121 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 7.619151e-01 0.118 0 0
RNA Polymerase III Transcription R-HSA-74158 7.619151e-01 0.118 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 7.619151e-01 0.118 0 0
Glycosphingolipid transport R-HSA-9845576 7.619151e-01 0.118 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 7.672105e-01 0.115 0 0
Aquaporin-mediated transport R-HSA-445717 7.672105e-01 0.115 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.673146e-01 0.115 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.673146e-01 0.115 0 0
Mitochondrial RNA degradation R-HSA-9836573 7.673146e-01 0.115 0 0
Complex III assembly R-HSA-9865881 7.673146e-01 0.115 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 7.742132e-01 0.111 0 0
Maple Syrup Urine Disease R-HSA-9865114 7.742132e-01 0.111 0 0
Scavenging by Class F Receptors R-HSA-3000484 7.742132e-01 0.111 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 7.742132e-01 0.111 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 7.742132e-01 0.111 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 7.742132e-01 0.111 0 0
GRB2 events in EGFR signaling R-HSA-179812 7.742132e-01 0.111 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 7.742132e-01 0.111 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 7.742132e-01 0.111 0 0
Signaling by LTK R-HSA-9842663 7.742132e-01 0.111 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 7.742132e-01 0.111 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 7.758799e-01 0.110 0 0
Heme signaling R-HSA-9707616 7.777726e-01 0.109 0 0
Acyl chain remodelling of PS R-HSA-1482801 7.827944e-01 0.106 0 0
Hyaluronan degradation R-HSA-2160916 7.827944e-01 0.106 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 7.827944e-01 0.106 0 0
PI3K Cascade R-HSA-109704 7.862621e-01 0.104 0 0
Signaling by FGFR2 in disease R-HSA-5655253 7.862621e-01 0.104 0 0
MET promotes cell motility R-HSA-8875878 7.879620e-01 0.103 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 7.879621e-01 0.103 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 7.896802e-01 0.103 0 0
Processing of SMDT1 R-HSA-8949664 7.942768e-01 0.100 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 7.942768e-01 0.100 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 7.942768e-01 0.100 0 0
FGFR1c ligand binding and activation R-HSA-190373 7.942768e-01 0.100 0 0
Chylomicron remodeling R-HSA-8963901 7.942768e-01 0.100 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 7.942768e-01 0.100 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 7.942768e-01 0.100 0 0
CD28 dependent Vav1 pathway R-HSA-389359 7.942768e-01 0.100 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 7.942768e-01 0.100 0 0
Maturation of nucleoprotein R-HSA-9683610 7.942768e-01 0.100 0 0
Interleukin-6 signaling R-HSA-1059683 7.942768e-01 0.100 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 7.942768e-01 0.100 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.973618e-01 0.098 0 0
Abacavir ADME R-HSA-2161522 7.973618e-01 0.098 0 0
Sphingolipid catabolism R-HSA-9845614 7.973618e-01 0.098 0 0
IGF1R signaling cascade R-HSA-2428924 7.977842e-01 0.098 0 0
Pentose phosphate pathway R-HSA-71336 8.000728e-01 0.097 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 8.003448e-01 0.097 0 0
Disorders of transmembrane transporters R-HSA-5619115 8.072358e-01 0.093 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 8.072447e-01 0.093 0 0
Integrin cell surface interactions R-HSA-216083 8.090326e-01 0.092 0 0
Signaling by FGFR3 in disease R-HSA-5655332 8.110567e-01 0.091 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 8.110567e-01 0.091 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 8.110567e-01 0.091 0 0
Insulin processing R-HSA-264876 8.110567e-01 0.091 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 8.110567e-01 0.091 0 0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV R-HSA-9859138 8.125585e-01 0.090 0 0
Retrograde neurotrophin signalling R-HSA-177504 8.125585e-01 0.090 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 8.125585e-01 0.090 0 0
Removal of the Flap Intermediate R-HSA-69166 8.125585e-01 0.090 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 8.125585e-01 0.090 0 0
CRMPs in Sema3A signaling R-HSA-399956 8.125585e-01 0.090 0 0
Hydrolysis of LPC R-HSA-1483115 8.125585e-01 0.090 0 0
cGMP effects R-HSA-418457 8.125585e-01 0.090 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 8.125585e-01 0.090 0 0
Regulation of KIT signaling R-HSA-1433559 8.125585e-01 0.090 0 0
Non-canonical inflammasome activation R-HSA-9686114 8.125585e-01 0.090 0 0
HDL assembly R-HSA-8963896 8.125585e-01 0.090 0 0
Acyl chain remodeling of CL R-HSA-1482798 8.125585e-01 0.090 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 8.125585e-01 0.090 0 0
Amino acids regulate mTORC1 R-HSA-9639288 8.174465e-01 0.088 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 8.193108e-01 0.087 0 0
PI Metabolism R-HSA-1483255 8.228152e-01 0.085 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 8.239190e-01 0.084 0 0
Formation of the Early Elongation Complex R-HSA-113418 8.239190e-01 0.084 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 8.239190e-01 0.084 0 0
Insulin receptor recycling R-HSA-77387 8.239190e-01 0.084 0 0
Inflammasomes R-HSA-622312 8.239190e-01 0.084 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.239190e-01 0.084 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 8.292167e-01 0.081 0 0
Erythropoietin activates RAS R-HSA-9027284 8.292167e-01 0.081 0 0
SHC1 events in EGFR signaling R-HSA-180336 8.292167e-01 0.081 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 8.292167e-01 0.081 0 0
G beta:gamma signalling through BTK R-HSA-8964315 8.292167e-01 0.081 0 0
Processive synthesis on the lagging strand R-HSA-69183 8.292167e-01 0.081 0 0
Biotin transport and metabolism R-HSA-196780 8.292167e-01 0.081 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 8.292167e-01 0.081 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 8.292167e-01 0.081 0 0
DNA Damage Reversal R-HSA-73942 8.292167e-01 0.081 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 8.329648e-01 0.079 0 0
mRNA Capping R-HSA-72086 8.359885e-01 0.078 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 8.359885e-01 0.078 0 0
DARPP-32 events R-HSA-180024 8.359885e-01 0.078 0 0
Glucagon-type ligand receptors R-HSA-420092 8.359885e-01 0.078 0 0
Regulation of gene expression in beta cells R-HSA-210745 8.359885e-01 0.078 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 8.428440e-01 0.074 0 0
Phosphorylation of the APC/C R-HSA-176412 8.443953e-01 0.073 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 8.443953e-01 0.073 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 8.443953e-01 0.073 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 8.443953e-01 0.073 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 8.443953e-01 0.073 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 8.443953e-01 0.073 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 8.443953e-01 0.073 0 0
Activation of the phototransduction cascade R-HSA-2485179 8.443953e-01 0.073 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 8.443953e-01 0.073 0 0
Activation of SMO R-HSA-5635838 8.443953e-01 0.073 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 8.443953e-01 0.073 0 0
Atorvastatin ADME R-HSA-9754706 8.443953e-01 0.073 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 8.473046e-01 0.072 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 8.473046e-01 0.072 0 0
DAP12 signaling R-HSA-2424491 8.473046e-01 0.072 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 8.473046e-01 0.072 0 0
Interleukin-37 signaling R-HSA-9008059 8.473046e-01 0.072 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 8.480968e-01 0.072 0 0
IRS-mediated signalling R-HSA-112399 8.530998e-01 0.069 0 0
Platelet homeostasis R-HSA-418346 8.557967e-01 0.068 0 0
Mitochondrial biogenesis R-HSA-1592230 8.573620e-01 0.067 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 8.579058e-01 0.067 0 0
Molecules associated with elastic fibres R-HSA-2129379 8.579058e-01 0.067 0 0
Cargo concentration in the ER R-HSA-5694530 8.579058e-01 0.067 0 0
Aspartate and asparagine metabolism R-HSA-8963693 8.579058e-01 0.067 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 8.582257e-01 0.066 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 8.582257e-01 0.066 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 8.582257e-01 0.066 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 8.582257e-01 0.066 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 8.610307e-01 0.065 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.668231e-01 0.062 0 0
Stimuli-sensing channels R-HSA-2672351 8.675270e-01 0.062 0 0
DAG1 glycosylations R-HSA-8931838 8.678296e-01 0.062 0 0
Inwardly rectifying K+ channels R-HSA-1296065 8.678296e-01 0.062 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 8.684637e-01 0.061 0 0
Extension of Telomeres R-HSA-180786 8.685926e-01 0.061 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 8.694958e-01 0.061 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 8.694958e-01 0.061 0 0
Somitogenesis R-HSA-9824272 8.694958e-01 0.061 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 8.708276e-01 0.060 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 8.708276e-01 0.060 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 8.708276e-01 0.060 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 8.708276e-01 0.060 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 8.708276e-01 0.060 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 8.708276e-01 0.060 0 0
Choline catabolism R-HSA-6798163 8.708276e-01 0.060 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.708276e-01 0.060 0 0
SLC transporter disorders R-HSA-5619102 8.760976e-01 0.057 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.774489e-01 0.057 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.774489e-01 0.057 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 8.823100e-01 0.054 0 0
Polo-like kinase mediated events R-HSA-156711 8.823100e-01 0.054 0 0
FGFR1 ligand binding and activation R-HSA-190242 8.823100e-01 0.054 0 0
Mismatch Repair R-HSA-5358508 8.823100e-01 0.054 0 0
Synaptic adhesion-like molecules R-HSA-8849932 8.823100e-01 0.054 0 0
Apoptotic factor-mediated response R-HSA-111471 8.823100e-01 0.054 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 8.823100e-01 0.054 0 0
Formation of paraxial mesoderm R-HSA-9793380 8.826587e-01 0.054 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.857908e-01 0.053 0 0
Mitochondrial protein import R-HSA-1268020 8.891873e-01 0.051 0 0
Keratinization R-HSA-6805567 8.909826e-01 0.050 0 0
GPER1 signaling R-HSA-9634597 8.920735e-01 0.050 0 0
Metal ion SLC transporters R-HSA-425410 8.920735e-01 0.050 0 0
Co-stimulation by CD28 R-HSA-389356 8.920735e-01 0.050 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 8.927724e-01 0.049 0 0
Germ layer formation at gastrulation R-HSA-9754189 8.927724e-01 0.049 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 8.927724e-01 0.049 0 0
Pyrimidine biosynthesis R-HSA-500753 8.927724e-01 0.049 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 8.927724e-01 0.049 0 0
Maturation of nucleoprotein R-HSA-9694631 8.927724e-01 0.049 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 8.927724e-01 0.049 0 0
Signal amplification R-HSA-392518 8.938978e-01 0.049 0 0
Hyaluronan metabolism R-HSA-2142845 8.938978e-01 0.049 0 0
Insulin receptor signalling cascade R-HSA-74751 9.012965e-01 0.045 0 0
Ion transport by P-type ATPases R-HSA-936837 9.012965e-01 0.045 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.014666e-01 0.045 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.014666e-01 0.045 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 9.023052e-01 0.045 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 9.023052e-01 0.045 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.023052e-01 0.045 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 9.023052e-01 0.045 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 9.023052e-01 0.045 0 0
Signaling by NODAL R-HSA-1181150 9.023052e-01 0.045 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.023052e-01 0.045 0 0
Creatine metabolism R-HSA-71288 9.023052e-01 0.045 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 9.023052e-01 0.045 0 0
Azathioprine ADME R-HSA-9748787 9.051129e-01 0.043 0 0
Gastrulation R-HSA-9758941 9.060675e-01 0.043 0 0
Triglyceride catabolism R-HSA-163560 9.085289e-01 0.042 0 0
GPVI-mediated activation cascade R-HSA-114604 9.085289e-01 0.042 0 0
RUNX2 regulates bone development R-HSA-8941326 9.085289e-01 0.042 0 0
G1/S-Specific Transcription R-HSA-69205 9.085289e-01 0.042 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.085289e-01 0.042 0 0
G-protein activation R-HSA-202040 9.109911e-01 0.040 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 9.109911e-01 0.040 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 9.109911e-01 0.040 0 0
ERK/MAPK targets R-HSA-198753 9.109911e-01 0.040 0 0
Lagging Strand Synthesis R-HSA-69186 9.109911e-01 0.040 0 0
Abacavir metabolism R-HSA-2161541 9.109911e-01 0.040 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 9.109911e-01 0.040 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 9.109911e-01 0.040 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 9.109911e-01 0.040 0 0
Basigin interactions R-HSA-210991 9.109911e-01 0.040 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.109911e-01 0.040 0 0
Signaling by Insulin receptor R-HSA-74752 9.113069e-01 0.040 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.123471e-01 0.040 0 0
Ion channel transport R-HSA-983712 9.150660e-01 0.039 0 0
Voltage gated Potassium channels R-HSA-1296072 9.151150e-01 0.039 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.151150e-01 0.039 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 9.189052e-01 0.037 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.189052e-01 0.037 0 0
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377 9.189052e-01 0.037 0 0
Elastic fibre formation R-HSA-1566948 9.212535e-01 0.036 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 9.212535e-01 0.036 0 0
Nucleotide biosynthesis R-HSA-8956320 9.220102e-01 0.035 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 9.240628e-01 0.034 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.261160e-01 0.033 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 9.261160e-01 0.033 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 9.261160e-01 0.033 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 9.261160e-01 0.033 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.261160e-01 0.033 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 9.261160e-01 0.033 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 9.269720e-01 0.033 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.269720e-01 0.033 0 0
G alpha (z) signalling events R-HSA-418597 9.316954e-01 0.031 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 9.322967e-01 0.030 0 0
HIV Transcription Elongation R-HSA-167169 9.322967e-01 0.030 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 9.322967e-01 0.030 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 9.326860e-01 0.030 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 9.326860e-01 0.030 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.326860e-01 0.030 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 9.326860e-01 0.030 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.326860e-01 0.030 0 0
Formation of the ureteric bud R-HSA-9830674 9.326860e-01 0.030 0 0
Synthesis of UDP-N-acetyl-glucosamine R-HSA-446210 9.326860e-01 0.030 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.326860e-01 0.030 0 0
Carnitine shuttle R-HSA-200425 9.326860e-01 0.030 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 9.326860e-01 0.030 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.327261e-01 0.030 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.330383e-01 0.030 0 0
tRNA processing R-HSA-72306 9.347692e-01 0.029 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.361110e-01 0.029 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.372523e-01 0.028 0 0
Maturation of spike protein R-HSA-9694548 9.372523e-01 0.028 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.383992e-01 0.028 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.386722e-01 0.027 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.386722e-01 0.027 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.386722e-01 0.027 0 0
Interleukin-6 family signaling R-HSA-6783589 9.386722e-01 0.027 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.388078e-01 0.027 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.396093e-01 0.027 0 0
Synthesis of PA R-HSA-1483166 9.402617e-01 0.027 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.416547e-01 0.026 0 0
Intra-Golgi traffic R-HSA-6811438 9.418624e-01 0.026 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.424492e-01 0.026 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.441264e-01 0.025 0 0
G protein gated Potassium channels R-HSA-1296059 9.441264e-01 0.025 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 9.441264e-01 0.025 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 9.441264e-01 0.025 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.441264e-01 0.025 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.441264e-01 0.025 0 0
Laminin interactions R-HSA-3000157 9.441264e-01 0.025 0 0
Triglyceride metabolism R-HSA-8979227 9.478234e-01 0.023 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.478234e-01 0.023 0 0
Regulation of beta-cell development R-HSA-186712 9.478234e-01 0.023 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.490958e-01 0.023 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 9.490958e-01 0.023 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 9.490958e-01 0.023 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.490958e-01 0.023 0 0
TRP channels R-HSA-3295583 9.490958e-01 0.023 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.491450e-01 0.023 0 0
Signaling by SCF-KIT R-HSA-1433557 9.501336e-01 0.022 0 0
tRNA Aminoacylation R-HSA-379724 9.512608e-01 0.022 0 0
Metabolism of polyamines R-HSA-351202 9.512608e-01 0.022 0 0
Neurotransmitter release cycle R-HSA-112310 9.520054e-01 0.021 0 0
Leishmania infection R-HSA-9658195 9.533779e-01 0.021 0 0
Parasitic Infection Pathways R-HSA-9824443 9.533779e-01 0.021 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 9.536234e-01 0.021 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 9.536234e-01 0.021 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 9.536234e-01 0.021 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.536234e-01 0.021 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 9.536234e-01 0.021 0 0
Triglyceride biosynthesis R-HSA-75109 9.536234e-01 0.021 0 0
Synthesis of PE R-HSA-1483213 9.536234e-01 0.021 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.536234e-01 0.021 0 0
Proteasome assembly R-HSA-9907900 9.538356e-01 0.021 0 0
DAP12 interactions R-HSA-2172127 9.538356e-01 0.021 0 0
Parasite infection R-HSA-9664407 9.546550e-01 0.020 0 0
Leishmania phagocytosis R-HSA-9664417 9.546550e-01 0.020 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.546550e-01 0.020 0 0
Signaling by PDGF R-HSA-186797 9.575105e-01 0.019 0 0
HIV elongation arrest and recovery R-HSA-167287 9.577487e-01 0.019 0 0
Pausing and recovery of HIV elongation R-HSA-167290 9.577487e-01 0.019 0 0
Prednisone ADME R-HSA-9757110 9.577487e-01 0.019 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.578567e-01 0.019 0 0
Peptide hormone metabolism R-HSA-2980736 9.591081e-01 0.018 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.604661e-01 0.018 0 0
Thyroxine biosynthesis R-HSA-209968 9.615071e-01 0.017 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.615071e-01 0.017 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.620421e-01 0.017 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.628486e-01 0.016 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.649315e-01 0.016 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.649315e-01 0.016 0 0
Neurotransmitter clearance R-HSA-112311 9.649315e-01 0.016 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.651705e-01 0.015 0 0
Interferon gamma signaling R-HSA-877300 9.661897e-01 0.015 0 0
Disease R-HSA-1643685 9.665913e-01 0.015 0 0
Downstream signal transduction R-HSA-186763 9.680514e-01 0.014 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.687265e-01 0.014 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.693706e-01 0.014 0 0
Kidney development R-HSA-9830369 9.700025e-01 0.013 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.700025e-01 0.013 0 0
Potassium Channels R-HSA-1296071 9.701169e-01 0.013 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.731574e-01 0.012 0 0
The phototransduction cascade R-HSA-2514856 9.732808e-01 0.012 0 0
Post-translational protein modification R-HSA-597592 9.744028e-01 0.011 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.758432e-01 0.011 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.774037e-01 0.010 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.774305e-01 0.010 0 0
Neddylation R-HSA-8951664 9.776838e-01 0.010 0 0
eNOS activation R-HSA-203615 9.779928e-01 0.010 0 0
RA biosynthesis pathway R-HSA-5365859 9.779928e-01 0.010 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 9.779928e-01 0.010 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 9.799513e-01 0.009 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.799513e-01 0.009 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.799513e-01 0.009 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.817356e-01 0.008 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.818744e-01 0.008 0 0
Lysine catabolism R-HSA-71064 9.833612e-01 0.007 0 0
Dectin-2 family R-HSA-5621480 9.834179e-01 0.007 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.848422e-01 0.007 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.858769e-01 0.006 0 0
Innate Immune System R-HSA-168249 9.859668e-01 0.006 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.873237e-01 0.006 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.874207e-01 0.005 0 0
Extracellular matrix organization R-HSA-1474244 9.884659e-01 0.005 0 0
G alpha (q) signalling events R-HSA-416476 9.888000e-01 0.005 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.889131e-01 0.005 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 9.895608e-01 0.005 0 0
Complex I biogenesis R-HSA-6799198 9.897758e-01 0.004 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.897758e-01 0.004 0 0
Activation of GABAB receptors R-HSA-991365 9.904902e-01 0.004 0 0
GABA B receptor activation R-HSA-977444 9.904902e-01 0.004 0 0
PPARA activates gene expression R-HSA-1989781 9.907623e-01 0.004 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.919889e-01 0.003 0 0
Surfactant metabolism R-HSA-5683826 9.921084e-01 0.003 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.925289e-01 0.003 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.928111e-01 0.003 0 0
Synthesis of PC R-HSA-1483191 9.940346e-01 0.003 0 0
COPII-mediated vesicle transport R-HSA-204005 9.942248e-01 0.003 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.944881e-01 0.002 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.945659e-01 0.002 0 0
ECM proteoglycans R-HSA-3000178 9.946803e-01 0.002 0 0
Retinoid metabolism and transport R-HSA-975634 9.946803e-01 0.002 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.954909e-01 0.002 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.958455e-01 0.002 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.958925e-01 0.002 0 0
Metabolism of proteins R-HSA-392499 9.963444e-01 0.002 0 0
Collagen formation R-HSA-1474290 9.964413e-01 0.002 0 0
G alpha (s) signalling events R-HSA-418555 9.965562e-01 0.001 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.966383e-01 0.001 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.976763e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.977528e-01 0.001 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.977582e-01 0.001 0 0
GABA receptor activation R-HSA-977443 9.982267e-01 0.001 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.982267e-01 0.001 0 0
Endogenous sterols R-HSA-211976 9.983848e-01 0.001 0 0
Xenobiotics R-HSA-211981 9.987794e-01 0.001 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.988977e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.988977e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.990777e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.991169e-01 0.000 0 0
O-linked glycosylation of mucins R-HSA-913709 9.991599e-01 0.000 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.991599e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.993031e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.993031e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.993421e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.993652e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.994218e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.994366e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.994614e-01 0.000 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.995632e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.995970e-01 0.000 0 0
Cholesterol biosynthesis R-HSA-191273 9.996700e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.996700e-01 0.000 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.996994e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.997316e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.997576e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.998117e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.998478e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.998506e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.998577e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.998802e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.998895e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.998943e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999234e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999322e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.999442e-01 0.000 0 0
Scavenging of heme from plasma R-HSA-2168880 9.999492e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999502e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.999537e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999665e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.999731e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999763e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999801e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999949e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999970e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999972e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999973e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999975e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999979e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999981e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999986e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999989e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999989e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999989e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999996e-01 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 9.999999e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.999999e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Metabolism of steroids R-HSA-8957322 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways